-- dump date 20140619_113537 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 85963000001 SEQ_END SEQ_END NC_000921.1 1643831 1643831 DR NC_000921.1; contig end 1643831..1643831 Helicobacter pylori J99 NP_222723.1 CDS nusB NC_000921.1 51 467 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(51..467) Helicobacter pylori J99 889080 NP_222724.1 CDS ribH NC_000921.1 469 939 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(469..939) Helicobacter pylori J99 888968 NP_222725.1 CDS kdsA NC_000921.1 949 1779 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(949..1779) Helicobacter pylori J99 889344 NP_222726.1 CDS icfA NC_000921.1 1766 2431 R similar to H. pylori 26695 gene HP0004; carbonic anhydrase complement(1766..2431) Helicobacter pylori J99 889283 NP_222727.1 CDS pyrF NC_000921.1 2552 3235 D OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2552..3235 Helicobacter pylori J99 889292 NP_222728.1 CDS panC NC_000921.1 3235 4065 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3235..4065 Helicobacter pylori J99 889294 NP_222729.1 CDS jhp0007 NC_000921.1 5436 7443 R similar to TIGR HP0009; expression of this protein is predicted to be regulated by slipped-strand repair at the (CT) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein complement(join(5436..7413,7415..7443)) Helicobacter pylori J99 889297 NP_222730.1 CDS groEL NC_000921.1 7758 9398 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL complement(7758..9398) Helicobacter pylori J99 889244 NP_222731.1 CDS groES NC_000921.1 9423 9779 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(9423..9779) Helicobacter pylori J99 889260 NP_222732.1 CDS dnaG NC_000921.1 10067 11746 D synthesizes RNA primers at the replication forks; DNA primase 10067..11746 Helicobacter pylori J99 889025 NP_222733.1 CDS jhp0011 NC_000921.1 11743 12795 D similar to H. pylori 26695 gene HP0013; hypothetical protein 11743..12795 Helicobacter pylori J99 889084 NP_222734.1 CDS jhp0012 NC_000921.1 12885 13712 D similar to H. pylori 26695 gene HP0014; hypothetical protein 12885..13712 Helicobacter pylori J99 889033 NP_222735.1 CDS jhp0013 NC_000921.1 13859 14140 D similar to H. pylori 26695 gene HP0015; hypothetical protein 13859..14140 Helicobacter pylori J99 889209 NP_222736.1 CDS jhp0014 NC_000921.1 14140 14403 D similar to H. pylori 26695 gene HP0016; hypothetical protein 14140..14403 Helicobacter pylori J99 889227 NP_222737.1 CDS virB4_1 NC_000921.1 14405 16768 D similar to H. pylori 26695 gene HP0017; DNA transfer protein 14405..16768 Helicobacter pylori J99 889231 NP_222738.1 CDS jhp0016 NC_000921.1 17008 18417 D similar to H. pylori 26695 gene HP0018; hypothetical protein 17008..18417 Helicobacter pylori J99 889054 NP_222739.1 CDS cheV_1 NC_000921.1 18524 19489 D similar to H. pylori 26695 gene HP0019; chemotaxis protein 18524..19489 Helicobacter pylori J99 889258 NP_222740.1 CDS nspC NC_000921.1 19486 20703 D similar to H. pylori 26695 gene HP0020; carboxynorspermidine decarboxylase 19486..20703 Helicobacter pylori J99 889151 NP_222741.1 CDS jhp0019 NC_000921.1 20764 21339 R inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase complement(20764..21339) Helicobacter pylori J99 889105 NP_222742.1 CDS jhp0020 NC_000921.1 21350 22921 R attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase complement(21350..22921) Helicobacter pylori J99 889071 NP_222743.1 CDS jhp0021 NC_000921.1 23538 25610 R similar to H. pylori 26695 gene HP0025; hypothetical protein complement(23538..25610) Helicobacter pylori J99 889066 NP_222744.1 CDS gltA NC_000921.1 26315 27595 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(26315..27595) Helicobacter pylori J99 889056 NP_222745.1 CDS icd NC_000921.1 27796 29073 D similar to H. pylori 26695 gene HP0027; isocitrate dehydrogenase 27796..29073 Helicobacter pylori J99 889267 NP_222746.1 CDS jhp0024 NC_000921.1 29138 29665 D similar to H. pylori 26695 gene HP0028; hypothetical protein 29138..29665 Helicobacter pylori J99 889075 NP_222747.1 CDS bioD NC_000921.1 29642 30298 R similar to H. pylori 26695 gene HP0029; dethiobiotin synthetase complement(29642..30298) Helicobacter pylori J99 889076 NP_222748.1 CDS jhp0026 NC_000921.1 30302 31999 R similar to H. pylori 26695 gene HP0030; hypothetical protein complement(30302..31999) Helicobacter pylori J99 888999 NP_222749.1 CDS jhp0027 NC_000921.1 32111 32524 D similar to H. pylori 26695 gene HP0031; hypothetical protein 32111..32524 Helicobacter pylori J99 889139 NP_222750.1 CDS jhp0028 NC_000921.1 32526 32798 D similar to H. pylori 26695 gene HP0032; hypothetical protein 32526..32798 Helicobacter pylori J99 889155 NP_222751.1 CDS clpA NC_000921.1 32798 35026 D similar to H. pylori 26695 gene HP0033; ATP-dependent protease ATP-binding protein 32798..35026 Helicobacter pylori J99 889269 NP_222752.1 CDS panD NC_000921.1 35016 35369 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 35016..35369 Helicobacter pylori J99 889064 NP_222753.1 CDS jhp0031 NC_000921.1 35372 35674 D similar to H. pylori 26695 gene HP0035; hypothetical protein 35372..35674 Helicobacter pylori J99 888974 NP_222754.1 CDS jhp0032 NC_000921.1 35671 36678 D similar to H. pylori 26695 gene HP0036; hypothetical protein 35671..36678 Helicobacter pylori J99 889165 NP_222755.1 CDS jhp0033 NC_000921.1 36686 37741 D similar to H. pylori 26695 gene HP0037; hypothetical protein 36686..37741 Helicobacter pylori J99 889202 NP_222756.1 CDS comB1 NC_000921.1 37867 38610 D similar to H. pylori 26695 gene HP0038; DNA transformation competancy 37867..38610 Helicobacter pylori J99 889161 NP_222757.1 CDS comB2 NC_000921.1 38610 39596 D similar to H. pylori 26695 gene HP0039 and HP0040; DNA transformation compentancy 38610..39596 Helicobacter pylori J99 889184 NP_222758.1 CDS comB3 NC_000921.1 39589 40719 D similar to H. pylori 26695 gene HP0041 and HP0042; DNA transformation compentancy 39589..40719 Helicobacter pylori J99 889038 NP_222759.1 CDS manC NC_000921.1 40789 42201 D similar to H. pylori 26695 gene HP0043; phosphomannose isomerase/GDP-mannose pyrophosphorylase 40789..42201 Helicobacter pylori J99 889003 NP_222760.1 CDS gmd NC_000921.1 42242 43387 D similar to H. pylori 26695 gene HP0044; GDP-D-mannose dehydratase 42242..43387 Helicobacter pylori J99 889028 NP_222761.1 CDS jhp0039 NC_000921.1 43380 44312 D similar to H. pylori 26695 gene HP0045; sugar nucleotide biosynthesis 43380..44312 Helicobacter pylori J99 888984 NP_222762.1 CDS hypE NC_000921.1 45190 46188 R similar to H. pylori 26695 gene HP0047; hydrogenase expression/formation protein complement(45190..46188) Helicobacter pylori J99 889280 NP_222763.1 CDS jhp0041 NC_000921.1 46191 48464 R similar to H. pylori 26695 gene HP0048; transcriptional regulator complement(46191..48464) Helicobacter pylori J99 890251 NP_222764.1 CDS jhp0042 NC_000921.1 48440 49432 R similar to H. pylori 26695 gene HP0049; hypothetical protein complement(48440..49432) Helicobacter pylori J99 890068 NP_222765.1 CDS jhp0043 NC_000921.1 49491 50183 R similar to H. pylori 26695 gene HP0050; type II DNA modification enzyme complement(49491..50183) Helicobacter pylori J99 889366 NP_222766.1 CDS jhp0044 NC_000921.1 50161 50718 R type II DNA modification enzyme complement(50161..50718) Helicobacter pylori J99 889369 NP_222767.1 CDS jhp0045 NC_000921.1 51152 52183 R type II DNA modification enzyme complement(51152..52183) Helicobacter pylori J99 889340 NP_222768.1 CDS jhp0046 NC_000921.1 52193 52975 R type II restriction enzyme complement(52193..52975) Helicobacter pylori J99 889327 NP_222769.1 CDS putP NC_000921.1 53403 54893 R similar to H. pylori 26695 gene HP0055; sodium/proline symporter complement(53403..54893) Helicobacter pylori J99 890457 NP_222770.1 CDS putA NC_000921.1 54920 58477 R similar to H. pylori 26695 gene HP0056; proline/pyrroline-5-carboxylate dehydrogenase complement(54920..58477) Helicobacter pylori J99 890440 NP_222771.1 CDS jhp0049 NC_000921.1 58798 59007 D similar to H. pylori 26695 gene HP0057; hypothetical protein 58798..59007 Helicobacter pylori J99 890461 NP_222772.1 CDS jhp0050 NC_000921.1 59335 59997 D similar to H. pylori 26695 gene HP0058; hypothetical protein 59335..59997 Helicobacter pylori J99 890430 NP_222773.1 CDS jhp0051 NC_000921.1 60127 60489 D similar to H. pylori 26695 gene HP0058; hypothetical protein 60127..60489 Helicobacter pylori J99 890443 NP_222774.1 CDS jhp0052 NC_000921.1 60490 61473 D similar to H. pylori 26695 gene HP0059; hypothetical protein 60490..61473 Helicobacter pylori J99 890447 NP_222775.1 CDS jhp0053 NC_000921.1 61484 61915 D similar to H. pylori 26695 gene HP0060; hypothetical protein 61484..61915 Helicobacter pylori J99 890453 NP_222776.1 CDS jhp0054 NC_000921.1 62096 63664 D similar to H. pylori 26695 gene HP0060; hypothetical protein 62096..63664 Helicobacter pylori J99 890444 NP_222777.1 CDS jhp0055 NC_000921.1 63665 63901 D similar to H. pylori 26695 gene HP0060; hypothetical protein 63665..63901 Helicobacter pylori J99 890449 NP_222778.1 CDS jhp0056 NC_000921.1 63898 64467 D similar to H. pylori 26695 gene HP0061; hypothetical protein 63898..64467 Helicobacter pylori J99 890441 NP_222779.1 CDS jhp0057 NC_000921.1 64483 64743 D similar to H. pylori 26695 gene HP0062; hypothetical protein 64483..64743 Helicobacter pylori J99 890429 NP_222780.1 CDS jhp0058 NC_000921.1 64754 66256 D similar to H. pylori 26695 gene HP0063; hypothetical protein 64754..66256 Helicobacter pylori J99 890432 NP_222781.1 CDS jhp0059 NC_000921.1 66226 66645 D similar to H. pylori 26695 gene HP0064; hypothetical protein 66226..66645 Helicobacter pylori J99 890437 NP_222782.1 CDS jhp0060 NC_000921.1 66647 67000 D similar to H. pylori 26695 gene HP0065; hypothetical protein 66647..67000 Helicobacter pylori J99 890425 NP_222783.1 CDS jhp0061 NC_000921.1 66993 69413 D similar to H. pylori 26695 gene HP0066; hypothetical protein 66993..69413 Helicobacter pylori J99 890428 NP_222784.1 CDS ureH NC_000921.1 69487 70284 R similar to H. pylori 26695 gene HP0067; urease accessory protein complement(69487..70284) Helicobacter pylori J99 890427 NP_222785.1 CDS ureG NC_000921.1 70284 70883 R similar to H. pylori 26695 gene HP0068; urease accessory protein complement(70284..70883) Helicobacter pylori J99 890411 NP_222786.1 CDS ureF NC_000921.1 70912 71682 R similar to H. pylori 26695 gene HP0069; urease accessory protein complement(70912..71682) Helicobacter pylori J99 890419 NP_222787.1 CDS ureE NC_000921.1 71706 72218 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(71706..72218) Helicobacter pylori J99 890417 NP_222788.1 CDS ureI NC_000921.1 72220 72807 R similar to H. pylori 26695 gene HP0071; urea transporter complement(72220..72807) Helicobacter pylori J99 890415 NP_222789.1 CDS ureB NC_000921.1 73031 74740 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta complement(73031..74740) Helicobacter pylori J99 890410 NP_222790.1 CDS ureA NC_000921.1 74744 75460 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha complement(74744..75460) Helicobacter pylori J99 890414 NP_222791.1 CDS lspA NC_000921.1 75814 76305 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(75814..76305) Helicobacter pylori J99 890403 NP_222792.1 CDS glmM NC_000921.1 76299 77636 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(76299..77636) Helicobacter pylori J99 890406 NP_222793.1 CDS rpsT NC_000921.1 77726 77995 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 77726..77995 Helicobacter pylori J99 890395 NP_222794.1 CDS prfA NC_000921.1 78114 79172 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 78114..79172 Helicobacter pylori J99 890378 NP_222795.1 CDS jhp0073 NC_000921.1 79586 80353 D similar to H. pylori 26695 gene HP0078 and HP0079; hypothetical protein 79586..80353 Helicobacter pylori J99 890384 NP_222796.1 CDS jhp0074 NC_000921.1 80604 82376 D similar to H. pylori 26695 gene HP0080; hypothetical protein 80604..82376 Helicobacter pylori J99 890392 NP_222797.1 CDS jhp0075 NC_000921.1 82800 84821 R similar to H. pylori 26695 gene HP0082; methyl-accepting chemotaxis protein (MCP) complement(82800..84821) Helicobacter pylori J99 890393 NP_222798.1 CDS rpsI NC_000921.1 84971 85360 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(84971..85360) Helicobacter pylori J99 890396 NP_222799.1 CDS rplM NC_000921.1 85357 85782 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(85357..85782) Helicobacter pylori J99 890381 NP_222800.1 CDS jhp0078 NC_000921.1 86134 86322 R similar to H. pylori 26695 gene HP0085; hypothetical protein complement(86134..86322) Helicobacter pylori J99 890388 NP_222801.1 CDS jhp0079 NC_000921.1 86329 87681 R similar to H. pylori 26695 gene HP0086; hypothetical protein complement(86329..87681) Helicobacter pylori J99 890383 NP_222802.1 CDS jhp0080 NC_000921.1 87735 89108 R similar to H. pylori 26695 gene HP0087; hypothetical protein complement(87735..89108) Helicobacter pylori J99 890385 NP_222803.1 CDS rpoD NC_000921.1 89128 91173 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(89128..91173) Helicobacter pylori J99 890377 NP_222804.1 CDS jhp0082 NC_000921.1 91396 92088 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(91396..92088) Helicobacter pylori J99 889391 NP_222805.1 CDS fabD NC_000921.1 92102 93031 R similar to H. pylori 26695 gene HP0090; ACP S-malonyltransferase complement(92102..93031) Helicobacter pylori J99 890372 NP_222806.1 CDS jhp0085 NC_000921.1 94286 95119 D similar to H. pylori 26695 gene HP0092; type II DNA modification (methyltransferase 94286..95119 Helicobacter pylori J99 890368 NP_222807.1 CDS jhp0086 NC_000921.1 95139 96039 R similar to TIGR HP0094; expression of this protein is predicted to be regulated by slipped-strand repair at the (C) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; alpha(1,2)fucosyltransferase complement(join(95139..95642,95644..96039)) Helicobacter pylori J99 890370 NP_222808.1 CDS jhp0087 NC_000921.1 96135 96665 R similar to H. pylori 26695 gene HP0095; hypothetical protein complement(96135..96665) Helicobacter pylori J99 890362 NP_222809.1 CDS jhp0088 NC_000921.1 96738 97682 D Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 96738..97682 Helicobacter pylori J99 890365 NP_222810.1 CDS jhp0089 NC_000921.1 97806 98519 R similar to H. pylori 26695 gene HP0097; hypothetical protein complement(97806..98519) Helicobacter pylori J99 889352 NP_222811.1 CDS thrC NC_000921.1 98623 100083 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(98623..100083) Helicobacter pylori J99 889337 NP_222812.1 CDS jhp0091 NC_000921.1 100277 102304 D similar to H. pylori 26695 gene HP0099; methyl-accepting chemotaxis protein (MCP) 100277..102304 Helicobacter pylori J99 889512 NP_222813.1 CDS jhp0092 NC_000921.1 102304 103410 D similar to H. pylori 26695 gene HP0100; hypothetical protein 102304..103410 Helicobacter pylori J99 889190 NP_222814.1 CDS jhp0093 NC_000921.1 103627 104388 D similar to H. pylori 26695 gene HP0101; hypothetical protein 103627..104388 Helicobacter pylori J99 889370 NP_222815.1 CDS jhp0094 NC_000921.1 104371 105153 R similar to H. pylori 26695 gene HP0102; hypothetical protein complement(104371..105153) Helicobacter pylori J99 889376 NP_222816.1 CDS jhp0095 NC_000921.1 105185 106879 R similar to H. pylori 26695 gene HP0103; methyl-accepting chemotaxis protein (MCP) complement(105185..106879) Helicobacter pylori J99 889481 NP_222817.1 CDS cpdB NC_000921.1 107095 108840 R similar to H. pylori 26695 gene HP0104; 2',3'-cyclic-nucleotide 2'-phosphodiesterase complement(107095..108840) Helicobacter pylori J99 889266 NP_222818.1 CDS jhp0097 NC_000921.1 108981 109439 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(108981..109439) Helicobacter pylori J99 889399 NP_222819.1 CDS metB NC_000921.1 109477 110619 R catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase complement(109477..110619) Helicobacter pylori J99 889500 NP_222820.1 CDS cysK NC_000921.1 110644 111561 R similar to H. pylori 26695 gene HP0107; cysteine synthase complement(110644..111561) Helicobacter pylori J99 889513 NP_222821.1 CDS jhp0100 NC_000921.1 111680 112138 D similar to H. pylori 26695 gene HP0108; hypothetical protein 111680..112138 Helicobacter pylori J99 889502 NP_222822.1 CDS dnaK NC_000921.1 112512 114374 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(112512..114374) Helicobacter pylori J99 889499 NP_222823.1 CDS grpE NC_000921.1 114404 114979 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(114404..114979) Helicobacter pylori J99 889489 NP_222824.1 CDS jhp0103 NC_000921.1 114979 115779 R Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor complement(114979..115779) Helicobacter pylori J99 889507 NP_222825.1 CDS jhp0104 NC_000921.1 116018 116656 D similar to H. pylori 26695 gene HP0112; hypothetical protein 116018..116656 Helicobacter pylori J99 889465 NP_222826.1 CDS jhp0105 NC_000921.1 116694 116990 D similar to H. pylori 26695 gene HP0113; hypothetical protein 116694..116990 Helicobacter pylori J99 889490 NP_222827.1 CDS jhp0106 NC_000921.1 117000 118883 R similar to H. pylori 26695 gene HP0114; hypothetical protein complement(117000..118883) Helicobacter pylori J99 889494 NP_222828.1 CDS flaB NC_000921.1 118931 120475 R FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B complement(118931..120475) Helicobacter pylori J99 889505 NP_222829.1 CDS topA_1 NC_000921.1 120641 122851 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 120641..122851 Helicobacter pylori J99 889464 NP_222830.1 CDS jhp0109 NC_000921.1 122844 123770 D similar to H. pylori 26695 gene HP0117; hypothetical protein 122844..123770 Helicobacter pylori J99 889487 NP_222831.1 CDS jhp0110 NC_000921.1 123915 125153 R similar to H. pylori 26695 gene HP0118; hypothetical protein complement(123915..125153) Helicobacter pylori J99 889480 NP_222832.1 CDS ppsA NC_000921.1 125252 127690 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(125252..127690) Helicobacter pylori J99 889485 NP_222833.1 CDS jhp0112 NC_000921.1 127876 128007 D similar to H. pylori 26695 gene HP0122; hypothetical protein 127876..128007 Helicobacter pylori J99 889466 NP_222834.1 CDS thrS NC_000921.1 128047 129885 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 128047..129885 Helicobacter pylori J99 889475 NP_222835.1 CDS infC NC_000921.1 129882 130493 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 129882..130493 Helicobacter pylori J99 889474 NP_222836.1 CDS rpmI NC_000921.1 130474 130668 D similar to H. pylori 26695 gene HP0125; 50S ribosomal protein L35 130474..130668 Helicobacter pylori J99 889467 NP_222837.1 CDS rplT NC_000921.1 130763 131113 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 130763..131113 Helicobacter pylori J99 889457 NP_222838.1 CDS jhp0117 NC_000921.1 131313 132173 D similar to H. pylori 26695 gene HP0127; hypothetical protein 131313..132173 Helicobacter pylori J99 889460 NP_222839.1 CDS jhp0118 NC_000921.1 132653 133084 D similar to H. pylori 26695 gene HP0129; hypothetical protein 132653..133084 Helicobacter pylori J99 889453 NP_222840.1 CDS jhp0119 NC_000921.1 133496 134353 D similar to H. pylori 26695 gene HP0130; hypothetical protein 133496..134353 Helicobacter pylori J99 889437 NP_222841.1 CDS sdaB NC_000921.1 134985 136352 R similar to H. pylori 26695 gene HP0132; L-serine/L-threoninedeaminase complement(134985..136352) Helicobacter pylori J99 889452 NP_222842.1 CDS sdaC NC_000921.1 136352 137593 R similar to H. pylori 26695 gene HP0133; L-serine transporter complement(136352..137593) Helicobacter pylori J99 889459 NP_222843.1 CDS aroF NC_000921.1 137774 139123 D similar to H. pylori 26695 gene HP0134; phospho-2-dehydro-3-deoxyheptonate aldolase 137774..139123 Helicobacter pylori J99 889424 NP_222844.1 CDS jhp0123 NC_000921.1 139412 139546 D similar to H. pylori 26695 gene HP0135; hypothetical protein 139412..139546 Helicobacter pylori J99 889446 NP_222845.1 CDS bcp NC_000921.1 139771 140229 R similar to H. pylori 26695 gene HP0136; bacterioferritin comigratory protein complement(139771..140229) Helicobacter pylori J99 889445 NP_222846.1 CDS jhp0125 NC_000921.1 140239 140874 R similar to H. pylori 26695 gene HP0137; hypothetical protein complement(140239..140874) Helicobacter pylori J99 889436 NP_222847.1 CDS jhp0126 NC_000921.1 140867 142312 R similar to H. pylori 26695 gene HP0138; iron-sulfur protein complement(140867..142312) Helicobacter pylori J99 889431 NP_222848.1 CDS jhp0127 NC_000921.1 142341 143069 R similar to H. pylori 26695 gene HP0139; hypothetical protein complement(142341..143069) Helicobacter pylori J99 889418 NP_222849.1 CDS lldP_1 NC_000921.1 143291 144940 D similar to H. pylori 26695 gene HP0140; L-lactate permease 143291..144940 Helicobacter pylori J99 889425 NP_222850.1 CDS lldP_2 NC_000921.1 144989 146644 D similar to H. pylori 26695 gene HP0141; L-lactate permease 144989..146644 Helicobacter pylori J99 889422 NP_222851.1 CDS mutY NC_000921.1 146668 147654 R similar to H. pylori 26695 gene HP0142; DNA glycosylase MutY complement(146668..147654) Helicobacter pylori J99 889408 NP_222852.1 CDS jhp0131 NC_000921.1 147655 149103 R similar to H. pylori 26695 gene HP0143; hypothetical protein complement(147655..149103) Helicobacter pylori J99 889427 NP_222853.1 CDS fixN NC_000921.1 149273 150739 D CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 149273..150739 Helicobacter pylori J99 889396 NP_222854.1 CDS fixO NC_000921.1 150752 151450 D CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 150752..151450 Helicobacter pylori J99 889394 NP_222855.1 CDS fixQ NC_000921.1 151461 151679 D similar to H. pylori 26695 gene HP0146; cytochrome oxidase (CBB3-type) 151461..151679 Helicobacter pylori J99 889412 NP_222856.1 CDS fixP NC_000921.1 151681 152559 D similar to H. pylori 26695 gene HP0147; cytochrome oxidase (CBB3-type) 151681..152559 Helicobacter pylori J99 889413 NP_222857.1 CDS jhp0136 NC_000921.1 152570 152776 D similar to H. pylori 26695 gene HP0148; hypothetical protein 152570..152776 Helicobacter pylori J99 889395 NP_222858.1 CDS jhp0137 NC_000921.1 152877 153470 D similar to H. pylori 26695 gene HP0149; hypothetical protein 152877..153470 Helicobacter pylori J99 889390 NP_222859.1 CDS jhp0138 NC_000921.1 153483 154064 D similar to H. pylori 26695 gene HP0150; hypothetical protein 153483..154064 Helicobacter pylori J99 889333 NP_222860.1 CDS jhp0139 NC_000921.1 154676 155443 D similar to H. pylori 26695 gene HP0151; hypothetical protein 154676..155443 Helicobacter pylori J99 889384 NP_222861.1 CDS jhp0140 NC_000921.1 155440 156303 R similar to H. pylori 26695 gene HP0152; hypothetical protein complement(155440..156303) Helicobacter pylori J99 889328 NP_222862.1 CDS recA NC_000921.1 156402 157445 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 156402..157445 Helicobacter pylori J99 889380 NP_222863.1 CDS eno NC_000921.1 157457 158737 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 157457..158737 Helicobacter pylori J99 889368 NP_222864.1 CDS jhp0143 NC_000921.1 158730 159005 D similar to H. pylori 26695 gene HP0155; hypothetical protein 158730..159005 Helicobacter pylori J99 889323 NP_222865.1 CDS jhp0144 NC_000921.1 159022 159618 D similar to H. pylori 26695 gene HP0156; hypothetical protein 159022..159618 Helicobacter pylori J99 889324 NP_222866.1 CDS aroK NC_000921.1 159623 160111 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 159623..160111 Helicobacter pylori J99 889302 NP_222867.1 CDS jhp0146 NC_000921.1 160133 161089 D similar to H. pylori 26695 gene HP0158; hypothetical protein 160133..161089 Helicobacter pylori J99 889319 NP_222868.1 CDS jhp0147 NC_000921.1 161086 162219 R similar to H. pylori 26695 gene HP0159; lipopolysaccharide biosynthesis protein complement(161086..162219) Helicobacter pylori J99 889315 NP_222869.1 CDS jhp0148 NC_000921.1 162372 163289 D similar to H. pylori 26695 gene HP0160; hypothetical protein 162372..163289 Helicobacter pylori J99 889026 NP_222870.1 CDS jhp0149 NC_000921.1 163970 164692 R similar to H. pylori 26695 gene HP0162; hypothetical protein complement(163970..164692) Helicobacter pylori J99 889158 NP_222871.1 CDS hemB NC_000921.1 164693 165664 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(164693..165664) Helicobacter pylori J99 889168 NP_222872.1 CDS jhp0151 NC_000921.1 165686 167014 R similar to H. pylori 26695 gene HP0164 and HP0165; histidine kinase sensor protein complement(165686..167014) Helicobacter pylori J99 889195 NP_222873.1 CDS jhp0152 NC_000921.1 167040 167717 R similar to H. pylori 26695 gene HP0166; transcriptional regulator complement(167040..167717) Helicobacter pylori J99 889237 NP_222874.1 CDS jhp0153 NC_000921.1 168125 168598 R similar to H. pylori 26695 gene HP0167; hypothetical protein complement(168125..168598) Helicobacter pylori J99 889277 NP_222875.1 CDS jhp0154 NC_000921.1 168577 168840 R similar to H. pylori 26695 gene HP0168; hypothetical protein complement(168577..168840) Helicobacter pylori J99 888981 NP_222876.1 CDS jhp0155 NC_000921.1 168887 170155 R similar to H. pylori 26695 gene HP0169; protease complement(168887..170155) Helicobacter pylori J99 889162 NP_222877.1 CDS jhp0156 NC_000921.1 170158 170889 R similar to H. pylori 26695 gene HP0170; hypothetical protein complement(170158..170889) Helicobacter pylori J99 889318 NP_222878.1 CDS prfB NC_000921.1 170959 172050 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(170959..172050) Helicobacter pylori J99 889002 NP_222879.1 CDS moeA NC_000921.1 172111 173283 R similar to H. pylori 26695 gene HP0172; molybdopterin biosynthesis protein complement(172111..173283) Helicobacter pylori J99 888998 NP_222880.1 CDS fliR NC_000921.1 173293 174060 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(173293..174060) Helicobacter pylori J99 889004 NP_222881.1 CDS jhp0160 NC_000921.1 174054 174782 R similar to H. pylori 26695 gene HP0174; hypothetical protein complement(174054..174782) Helicobacter pylori J99 888983 NP_222882.1 CDS jhp0161 NC_000921.1 175251 176150 D similar to H. pylori 26695 gene HP0175; peptidyl-prolyl cis-trans isomerase 175251..176150 Helicobacter pylori J99 890358 NP_222883.1 CDS fba NC_000921.1 176164 177087 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 176164..177087 Helicobacter pylori J99 889011 NP_222884.1 CDS efp NC_000921.1 177109 177672 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 177109..177672 Helicobacter pylori J99 889300 NP_222885.1 CDS jhp0164 NC_000921.1 178219 179565 D restriction enzyme 178219..179565 Helicobacter pylori J99 890357 NP_222886.1 CDS jhp0165 NC_000921.1 179558 180778 D hypothetical protein 179558..180778 Helicobacter pylori J99 889243 NP_222887.1 CDS neuB NC_000921.1 180850 181872 R similar to H. pylori 26695 gene HP0178; sialic acid synthase complement(180850..181872) Helicobacter pylori J99 890359 NP_222888.1 CDS jhp0167 NC_000921.1 181875 182516 R similar to H. pylori 26695 gene HP0179; ABC transporter ATP-binding protein complement(181875..182516) Helicobacter pylori J99 889252 NP_222889.1 CDS lnt NC_000921.1 182513 183790 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(182513..183790) Helicobacter pylori J99 889290 NP_222890.1 CDS jhp0169 NC_000921.1 184026 184736 D similar to H. pylori 26695 gene HP0181; hypothetical protein 184026..184736 Helicobacter pylori J99 889255 NP_222891.1 CDS lysS NC_000921.1 184746 186251 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 184746..186251 Helicobacter pylori J99 889288 NP_222892.1 CDS glyA NC_000921.1 186251 187501 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 186251..187501 Helicobacter pylori J99 889253 NP_222893.1 CDS jhp0172 NC_000921.1 187511 188053 D similar to H. pylori 26695 gene HP0184; hypothetical protein 187511..188053 Helicobacter pylori J99 889316 NP_222894.1 CDS jhp0173 NC_000921.1 188075 188881 D similar to H. pylori 26695 gene HP0185; hypothetical protein 188075..188881 Helicobacter pylori J99 889317 NP_222895.1 CDS jhp0174 NC_000921.1 189273 190976 R similar to H. pylori 26695 gene HP0186, HP0187, and HP0188; hypothetical protein complement(189273..190976) Helicobacter pylori J99 889291 NP_222896.1 CDS jhp0175 NC_000921.1 191132 191665 D similar to H. pylori 26695 gene HP0189; hypothetical protein 191132..191665 Helicobacter pylori J99 889241 NP_222897.1 CDS jhp0176 NC_000921.1 191672 193180 R similar to H. pylori 26695 gene HP0190; cardiolipin synthase complement(191672..193180) Helicobacter pylori J99 889240 NP_222898.1 CDS frdB NC_000921.1 193202 193939 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(193202..193939) Helicobacter pylori J99 889211 NP_222899.1 CDS frdA NC_000921.1 193932 196076 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(193932..196076) Helicobacter pylori J99 889257 NP_222900.1 CDS frdC NC_000921.1 196086 196853 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit complement(196086..196853) Helicobacter pylori J99 890355 NP_222901.1 CDS tpiA NC_000921.1 197063 197767 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 197063..197767 Helicobacter pylori J99 889254 NP_222902.1 CDS fabI NC_000921.1 197777 198604 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 197777..198604 Helicobacter pylori J99 889293 NP_222903.1 CDS lpxD NC_000921.1 198614 199624 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 198614..199624 Helicobacter pylori J99 889285 NP_222904.1 CDS metK NC_000921.1 199690 200847 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 199690..200847 Helicobacter pylori J99 889174 NP_222905.1 CDS ndk NC_000921.1 200914 201327 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 200914..201327 Helicobacter pylori J99 889157 NP_222906.1 CDS jhp0185 NC_000921.1 201352 201708 D similar to H. pylori 26695 gene HP0199; hypothetical protein 201352..201708 Helicobacter pylori J99 890023 NP_222907.1 CDS rpmF NC_000921.1 201724 201870 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 201724..201870 Helicobacter pylori J99 890231 NP_222908.1 CDS plsX NC_000921.1 201948 202967 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 201948..202967 Helicobacter pylori J99 889154 NP_222909.1 CDS fabH NC_000921.1 202991 203986 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 202991..203986 Helicobacter pylori J99 889248 NP_222910.1 CDS jhp0189 NC_000921.1 204010 204312 D similar to H. pylori 26695 gene HP0203; hypothetical protein 204010..204312 Helicobacter pylori J99 889247 NP_222911.1 CDS jhp0190 NC_000921.1 205002 205385 R similar to H. pylori 26695 gene HP0204; hypothetical protein complement(205002..205385) Helicobacter pylori J99 889301 NP_222912.1 CDS jhp0191 NC_000921.1 205463 208213 R similar to H. pylori 26695 gene HP0205; hypothetical protein complement(205463..208213) Helicobacter pylori J99 889309 NP_222913.1 CDS jhp0192 NC_000921.1 208250 208507 R similar to H. pylori 26695 gene HP0206; hypothetical protein complement(208250..208507) Helicobacter pylori J99 889308 NP_222914.1 CDS jhp0193 NC_000921.1 208604 209710 D similar to H. pylori 26695 gene HP0207; hypothetical protein 208604..209710 Helicobacter pylori J99 889295 NP_222915.1 CDS jhp0194 NC_000921.1 209770 210956 R similar to TIGR HP0208; expression of this protein is predicted to be regulated by slipped-strand repair at the (AG) dinucleotide repeat; length of the repeat has been artificially adjusted (removal of one dinucleotide) to give the full length protein; lipopolysaccharide biosynthesis protein complement(join(209770..210853,210856..210956)) Helicobacter pylori J99 889249 NP_222916.1 CDS jhp0195 NC_000921.1 211139 212455 D similar to H. pylori 26695 gene HP0209; hypothetical protein 211139..212455 Helicobacter pylori J99 889281 NP_222917.1 CDS htpG NC_000921.1 212559 214424 D molecular chaperone; heat shock protein 90 212559..214424 Helicobacter pylori J99 889307 NP_222918.1 CDS jhp0197 NC_000921.1 214621 215373 R similar to H. pylori 26695 gene HP0211; hypothetical protein complement(214621..215373) Helicobacter pylori J99 889172 NP_222919.1 CDS dapE NC_000921.1 215821 216987 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(215821..216987) Helicobacter pylori J99 889256 NP_222920.1 CDS gidA NC_000921.1 216997 218862 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(216997..218862) Helicobacter pylori J99 889262 NP_222921.1 CDS jhp0200 NC_000921.1 218958 220604 D similar to H. pylori 26695 gene HP0214; transporter 218958..220604 Helicobacter pylori J99 889217 NP_222922.1 CDS cdsA NC_000921.1 220617 221417 D similar to H. pylori 26695 gene HP0215; CDP-diacylglycerol synthase 220617..221417 Helicobacter pylori J99 889289 NP_222923.1 CDS jhp0202 NC_000921.1 221418 222524 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 221418..222524 Helicobacter pylori J99 889284 NP_222924.1 CDS jhp0203 NC_000921.1 222575 223733 D similar to TIGR HP0217; expression of this protein is predicted to be regulated by slipped-strand repair at the two (G) polynucleotide repeats; length of the second repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; hypothetical protein join(222575..223076,223078..223733) Helicobacter pylori J99 889199 NP_222925.1 CDS jhp0204 NC_000921.1 223802 224353 R similar to H. pylori 26695 gene HP0218; hypothetical protein complement(223802..224353) Helicobacter pylori J99 889092 NP_222926.1 CDS jhp0205 NC_000921.1 224473 224958 D similar to H. pylori 26695 gene HP0219; hypothetical protein 224473..224958 Helicobacter pylori J99 889091 NP_222927.1 CDS jhp0206 NC_000921.1 225126 226289 D catalyzes the removal of sulfur from cysteine to form alanine; cysteine desulfurase 225126..226289 Helicobacter pylori J99 889005 NP_222928.1 CDS jhp0207 NC_000921.1 226311 227291 D similar to H. pylori 26695 gene HP0221; nifU-like protein 226311..227291 Helicobacter pylori J99 889068 NP_222929.1 CDS jhp0208 NC_000921.1 227455 227715 D similar to H. pylori 26695 gene HP0222; hypothetical protein 227455..227715 Helicobacter pylori J99 889213 NP_222930.1 CDS radA NC_000921.1 227794 229140 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 227794..229140 Helicobacter pylori J99 889982 NP_222931.1 CDS jhp0210 NC_000921.1 229264 230343 D this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein 229264..230343 Helicobacter pylori J99 889429 NP_222932.1 CDS jhp0211 NC_000921.1 230748 231581 R similar to H. pylori 26695 gene HP0226; hypothetical protein complement(230748..231581) Helicobacter pylori J99 889985 NP_222933.1 CDS jhp0212 NC_000921.1 231799 233889 R similar to H. pylori 26695 gene HP0227; hypothetical protein complement(231799..233889) Helicobacter pylori J99 889419 NP_222934.1 CDS jhp0213 NC_000921.1 234143 235300 D similar to H. pylori 26695 gene HP0228; hypothetical protein 234143..235300 Helicobacter pylori J99 889984 NP_222935.1 CDS hopA NC_000921.1 235542 236993 R similar to H. pylori 26695 gene HP0229; Outer membrane protein/porin complement(235542..236993) Helicobacter pylori J99 889426 NP_222936.1 CDS kdsB NC_000921.1 237187 237918 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(237187..237918) Helicobacter pylori J99 889986 NP_222937.1 CDS jhp0216 NC_000921.1 238027 238824 D similar to H. pylori 26695 gene HP0231; hypothetical protein 238027..238824 Helicobacter pylori J99 889417 NP_222938.1 CDS jhp0217 NC_000921.1 238840 239487 D similar to H. pylori 26695 gene HP0232; hypothetical protein 238840..239487 Helicobacter pylori J99 889993 NP_222939.1 CDS jhp0218 NC_000921.1 239509 240681 D similar to H. pylori 26695 gene HP0233; hypothetical protein 239509..240681 Helicobacter pylori J99 889388 NP_222940.1 CDS jhp0219 NC_000921.1 240681 241211 D similar to H. pylori 26695 gene HP0234; hypothetical protein 240681..241211 Helicobacter pylori J99 889987 NP_222941.1 CDS jhp0220 NC_000921.1 241987 243054 R similar to H. pylori 26695 gene HP0235; hypothetical protein complement(241987..243054) Helicobacter pylori J99 889420 NP_222942.1 CDS jhp0221 NC_000921.1 243165 243536 R similar to H. pylori 26695 gene HP0236; hypothetical protein complement(243165..243536) Helicobacter pylori J99 889988 NP_222943.1 CDS hemC NC_000921.1 243536 244456 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(243536..244456) Helicobacter pylori J99 889411 NP_222944.1 CDS proS NC_000921.1 244467 246197 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(244467..246197) Helicobacter pylori J99 889989 NP_222945.1 CDS hemA NC_000921.1 246201 247550 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(246201..247550) Helicobacter pylori J99 889414 NP_222946.1 CDS ispB NC_000921.1 247550 248473 R similar to H. pylori 26695 gene HP0240; octaprenyl-diphosphate synthase complement(247550..248473) Helicobacter pylori J99 889990 NP_222947.1 CDS jhp0226 NC_000921.1 248483 248878 R similar to H. pylori 26695 gene HP0241; hypothetical protein complement(248483..248878) Helicobacter pylori J99 889416 NP_222948.1 CDS jhp0227 NC_000921.1 248871 249155 R similar to H. pylori 26695 gene HP0242; hypothetical protein complement(248871..249155) Helicobacter pylori J99 890000 NP_222949.1 CDS napA NC_000921.1 249176 249610 R similar to H. pylori 26695 gene HP0243; neutrophil-activating protein A complement(249176..249610) Helicobacter pylori J99 889403 NP_222950.1 CDS jhp0229 NC_000921.1 249818 250963 R similar to H. pylori 26695 gene HP0244; histidine kinase sensor protein complement(249818..250963) Helicobacter pylori J99 889991 NP_222951.1 CDS jhp0230 NC_000921.1 250960 251277 R similar to H. pylori 26695 gene HP0245; hypothetical protein complement(250960..251277) Helicobacter pylori J99 889415 NP_222952.1 CDS flgI NC_000921.1 251274 252302 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA complement(251274..252302) Helicobacter pylori J99 889996 NP_222953.1 CDS deaD NC_000921.1 252488 253963 D similar to H. pylori 26695 gene HP0247; ATP-dependent RNA helicase DeaD 252488..253963 Helicobacter pylori J99 889407 NP_222954.1 CDS jhp0233 NC_000921.1 253984 255072 D similar to H. pylori 26695 gene HP0248; hypothetical protein 253984..255072 Helicobacter pylori J99 889994 NP_222955.1 CDS jhp0234 NC_000921.1 255079 255618 D similar to H. pylori 26695 gene HP0249; hypothetical protein 255079..255618 Helicobacter pylori J99 889410 NP_222956.1 CDS jhp0235 NC_000921.1 255701 257251 R similar to H. pylori 26695 gene HP0250; ABC transporter ATP-binding protein complement(255701..257251) Helicobacter pylori J99 889997 NP_222957.1 CDS jhp0236 NC_000921.1 257261 258277 R similar to H. pylori 26695 gene HP0251; ABC transporter permease complement(257261..258277) Helicobacter pylori J99 889405 NP_222958.1 CDS jhp0237 NC_000921.1 258627 260066 D similar to H. pylori 26695 gene HP0252; hypothetical protein 258627..260066 Helicobacter pylori J99 889995 NP_222959.1 CDS jhp0238 NC_000921.1 260079 261494 D similar to H. pylori 26695 gene HP0253 and HP0254; hypothetical protein 260079..261494 Helicobacter pylori J99 889406 NP_222960.1 CDS purA NC_000921.1 261593 262828 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 261593..262828 Helicobacter pylori J99 889998 NP_222961.1 CDS jhp0240 NC_000921.1 262825 263253 D similar to H. pylori 26695 gene HP0256; hypothetical protein 262825..263253 Helicobacter pylori J99 889398 NP_222962.1 CDS jhp0241 NC_000921.1 263246 263914 D similar to H. pylori 26695 gene HP0257; hypothetical protein 263246..263914 Helicobacter pylori J99 890012 NP_222963.1 CDS jhp0242 NC_000921.1 263911 264966 D similar to H. pylori 26695 gene HP0258; hypothetical protein 263911..264966 Helicobacter pylori J99 889382 NP_222964.1 CDS xseA NC_000921.1 264979 266241 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 264979..266241 Helicobacter pylori J99 889999 NP_222965.1 CDS jhp0244 NC_000921.1 266260 267432 R similar to H. pylori 26695 gene HP0260; type II DNA modification (methyltransferase complement(266260..267432) Helicobacter pylori J99 889401 NP_222966.1 CDS jhp0245 NC_000921.1 267425 267883 R similar to H. pylori 26695 gene HP0261; hypothetical protein complement(267425..267883) Helicobacter pylori J99 890001 NP_222967.1 CDS jhp0246 NC_000921.1 267960 268478 D similar to H. pylori 26695 gene HP0262; hypothetical protein 267960..268478 Helicobacter pylori J99 889400 NP_222968.1 CDS jhp0247 NC_000921.1 268450 268659 D similar to H. pylori 26695 gene HP0262; hypothetical protein 268450..268659 Helicobacter pylori J99 890002 NP_222969.1 CDS jhp0248 NC_000921.1 268656 269414 D similar to H. pylori 26695 gene HP0263; type II DNA modification (methyltransferase 268656..269414 Helicobacter pylori J99 889402 NP_222970.1 CDS clpB NC_000921.1 269487 272057 D similar to H. pylori 26695 gene HP0264; heat shock protein 269487..272057 Helicobacter pylori J99 890003 NP_222971.1 CDS ccdA NC_000921.1 272114 272833 D similar to H. pylori 26695 gene HP0265; cytochrome C-type biogenesis protein 272114..272833 Helicobacter pylori J99 889397 NP_222972.1 CDS pyrC_1 NC_000921.1 272843 273979 D similar to H. pylori 26695 gene HP0266; dihydroorotase 272843..273979 Helicobacter pylori J99 890005 NP_222973.1 CDS orf1 NC_000921.1 273964 275193 D Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 273964..275193 Helicobacter pylori J99 889393 NP_222974.1 CDS jhp0253 NC_000921.1 275440 275682 D similar to H. pylori 26695 gene HP0268; hypothetical protein 275440..275682 Helicobacter pylori J99 890004 NP_222975.1 CDS jhp0254 NC_000921.1 275692 277005 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 275692..277005 Helicobacter pylori J99 889392 NP_222976.1 CDS jhp0255 NC_000921.1 277039 277692 D similar to H. pylori 26695 gene HP0270; hypothetical protein 277039..277692 Helicobacter pylori J99 890008 NP_222977.1 CDS jhp0256 NC_000921.1 277685 278668 D similar to H. pylori 26695 gene HP0271; hypothetical protein 277685..278668 Helicobacter pylori J99 889389 NP_222978.1 CDS jhp0257 NC_000921.1 278658 279191 D similar to H. pylori 26695 gene HP0272; hypothetical protein 278658..279191 Helicobacter pylori J99 890006 NP_222979.1 CDS jhp0258 NC_000921.1 279188 279727 D similar to H. pylori 26695 gene HP0273; hypothetical protein 279188..279727 Helicobacter pylori J99 889386 NP_222980.1 CDS jhp0259 NC_000921.1 279744 280142 D similar to H. pylori 26695 gene HP0274; hypothetical protein 279744..280142 Helicobacter pylori J99 890007 NP_222981.1 CDS jhp0260 NC_000921.1 280179 281474 D similar to H. pylori 26695 gene HP0275; hypothetical protein 280179..281474 Helicobacter pylori J99 889385 NP_222982.1 CDS jhp0261 NC_000921.1 281462 282019 D similar to H. pylori 26695 gene HP0276; hypothetical protein 281462..282019 Helicobacter pylori J99 890009 NP_222983.1 CDS jhp0262 NC_000921.1 282076 282330 D similar to H. pylori 26695 gene HP0277; ferredoxin 282076..282330 Helicobacter pylori J99 889387 NP_222984.1 CDS gppA NC_000921.1 282340 283794 D similar to H. pylori 26695 gene HP0278; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 282340..283794 Helicobacter pylori J99 890010 NP_222985.1 CDS waaC NC_000921.1 283791 284801 D similar to H. pylori 26695 gene HP0279; lipopolysaccharide heptosyltransferase-1 283791..284801 Helicobacter pylori J99 889379 NP_222986.1 CDS waaM NC_000921.1 284798 285784 D acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 284798..285784 Helicobacter pylori J99 890016 NP_222987.1 CDS tgt NC_000921.1 286040 287155 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(286040..287155) Helicobacter pylori J99 889378 NP_222988.1 CDS jhp0267 NC_000921.1 287212 288648 D similar to H. pylori 26695 gene HP0282; hypothetical protein 287212..288648 Helicobacter pylori J99 890011 NP_222989.1 CDS aroB NC_000921.1 288653 289684 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 288653..289684 Helicobacter pylori J99 889383 NP_222990.1 CDS jhp0269 NC_000921.1 289675 291246 D similar to H. pylori 26695 gene HP0284; hypothetical protein 289675..291246 Helicobacter pylori J99 889312 NP_222991.1 CDS jhp0270 NC_000921.1 291243 292499 D similar to H. pylori 26695 gene HP0285; hypothetical protein 291243..292499 Helicobacter pylori J99 890013 NP_222992.1 CDS ftsH_1 NC_000921.1 292486 294138 D similar to H. pylori 26695 gene HP0286; ATP-dependent zinc metallopeptidase 292486..294138 Helicobacter pylori J99 889381 NP_222993.1 CDS jhp0272 NC_000921.1 294141 294659 D similar to H. pylori 26695 gene HP0287; hypothetical protein 294141..294659 Helicobacter pylori J99 890015 NP_222994.1 CDS jhp0273 NC_000921.1 294672 295145 D similar to H. pylori 26695 gene HP0288; hypothetical protein 294672..295145 Helicobacter pylori J99 889304 NP_222995.1 CDS jhp0274 NC_000921.1 295213 303921 D similar to H. pylori 26695 gene HP0289; vacuolating cytotoxin (VacA) paralog 295213..303921 Helicobacter pylori J99 890022 NP_222996.1 CDS lysA NC_000921.1 303969 305186 D similar to H. pylori 26695 gene HP0290; diaminopimelate decarboxylase 303969..305186 Helicobacter pylori J99 889338 NP_222997.1 CDS jhp0276 NC_000921.1 305191 305493 D similar to H. pylori 26695 gene HP0291; hypothetical protein 305191..305493 Helicobacter pylori J99 890014 NP_222998.1 CDS jhp0277 NC_000921.1 305506 306378 D similar to H. pylori 26695 gene HP0292; hypothetical protein 305506..306378 Helicobacter pylori J99 890017 NP_222999.1 CDS pabB NC_000921.1 306379 308082 D similar to H. pylori 26695 gene HP0293; p-aminobenzoate synthetase 306379..308082 Helicobacter pylori J99 889377 NP_223000.1 CDS amiE NC_000921.1 308210 309229 D aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 308210..309229 Helicobacter pylori J99 890018 NP_223001.1 CDS flgL NC_000921.1 309554 312040 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL complement(309554..312040) Helicobacter pylori J99 890250 NP_223002.1 CDS rplU NC_000921.1 312283 312597 D similar to H. pylori 26695 gene HP0296; 50S ribosomal protein L21 312283..312597 Helicobacter pylori J99 890019 NP_223003.1 CDS rpmA NC_000921.1 312611 312877 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 312611..312877 Helicobacter pylori J99 889314 NP_223004.1 CDS dppA NC_000921.1 312996 314636 D similar to H. pylori 26695 gene HP0298; periplasmic dipeptide transport substrate-binding protein 312996..314636 Helicobacter pylori J99 890285 NP_223005.1 CDS dppB NC_000921.1 314647 315651 D similar to H. pylori 26695 gene HP0299; peptide ABC transporter permease 314647..315651 Helicobacter pylori J99 890020 NP_223006.1 CDS dppD NC_000921.1 316516 317379 D similar to H. pylori 26695 gene HP0301; peptide ABC transporter ATP-binding protein 316516..317379 Helicobacter pylori J99 890021 NP_223007.1 CDS dppF NC_000921.1 317376 318182 D similar to H. pylori 26695 gene HP0302; peptide ABC transporter ATP-binding protein 317376..318182 Helicobacter pylori J99 889335 NP_223008.1 CDS obgE NC_000921.1 318202 319284 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 318202..319284 Helicobacter pylori J99 889375 NP_223009.1 CDS jhp0289 NC_000921.1 319480 320475 D similar to H. pylori 26695 gene HP0304; hypothetical protein 319480..320475 Helicobacter pylori J99 889081 NP_223010.1 CDS jhp0290 NC_000921.1 320741 321295 D similar to H. pylori 26695 gene HP0305; hypothetical protein 320741..321295 Helicobacter pylori J99 889357 NP_223011.1 CDS hemL NC_000921.1 321305 322597 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 321305..322597 Helicobacter pylori J99 889367 NP_223012.1 CDS jhp0292 NC_000921.1 322587 322865 D similar to H. pylori 26695 gene HP0307; hypothetical protein 322587..322865 Helicobacter pylori J99 890334 NP_223013.1 CDS jhp0293 NC_000921.1 322881 323285 D similar to H. pylori 26695 gene HP0308; hypothetical protein 322881..323285 Helicobacter pylori J99 890328 NP_223014.1 CDS jhp0294 NC_000921.1 323369 324253 D similar to H. pylori 26695 gene HP0309; hypothetical protein 323369..324253 Helicobacter pylori J99 890311 NP_223015.1 CDS jhp0295 NC_000921.1 324266 325147 D similar to H. pylori 26695 gene HP0310; hypothetical protein 324266..325147 Helicobacter pylori J99 890305 NP_223016.1 CDS jhp0296 NC_000921.1 325193 325561 D similar to H. pylori 26695 gene HP0311; hypothetical protein 325193..325561 Helicobacter pylori J99 890294 NP_223017.1 CDS jhp0297 NC_000921.1 325561 326526 D similar to H. pylori 26695 gene HP0312; hypothetical protein 325561..326526 Helicobacter pylori J99 890292 NP_223018.1 CDS jhp0298 NC_000921.1 326532 327677 R similar to H. pylori 26695 gene HP0313; hypothetical protein complement(326532..327677) Helicobacter pylori J99 890289 NP_223019.1 CDS jhp0299 NC_000921.1 327878 328633 R similar to H. pylori 26695 gene HP0611 and HP0612; hypothetical protein complement(327878..328633) Helicobacter pylori J99 890272 NP_223020.1 CDS jhp0300 NC_000921.1 328633 329334 R similar to H. pylori 26695 gene HP0613; ABC transporter ATP-binding protein complement(328633..329334) Helicobacter pylori J99 890254 NP_223021.1 CDS jhp0301 NC_000921.1 329907 330662 R similar to H. pylori 26695 gene HP0318; hypothetical protein complement(329907..330662) Helicobacter pylori J99 890234 NP_223022.1 CDS argS NC_000921.1 330939 332564 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(330939..332564) Helicobacter pylori J99 890230 NP_223023.1 CDS jhp0303 NC_000921.1 332567 332806 R similar to H. pylori 26695 gene HP0320; hypothetical protein complement(332567..332806) Helicobacter pylori J99 889311 NP_223024.1 CDS gmk NC_000921.1 332878 333498 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(332878..333498) Helicobacter pylori J99 890174 NP_223025.1 CDS jhp0305 NC_000921.1 333491 334996 R similar to H. pylori 26695 gene HP0322; poly E-rich protein complement(333491..334996) Helicobacter pylori J99 890140 NP_223026.1 CDS jhp0306 NC_000921.1 335138 335680 D membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 335138..335680 Helicobacter pylori J99 889310 NP_223027.1 CDS jhp0307 NC_000921.1 335688 336425 R similar to H. pylori 26695 gene HP0324; hypothetical protein complement(335688..336425) Helicobacter pylori J99 890067 NP_223028.1 CDS flgH NC_000921.1 336559 337272 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 336559..337272 Helicobacter pylori J99 890080 NP_223029.1 CDS flaG NC_000921.1 338845 339387 D similar to H. pylori 26695 gene HP0327; flagellar biosynthesis protein 338845..339387 Helicobacter pylori J99 889345 NP_223030.1 CDS lpxK NC_000921.1 339320 340258 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(339320..340258) Helicobacter pylori J99 889374 NP_223031.1 CDS nadE NC_000921.1 340255 341037 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(340255..341037) Helicobacter pylori J99 889334 NP_223032.1 CDS ilvC NC_000921.1 341286 342278 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 341286..342278 Helicobacter pylori J99 889356 NP_223033.1 CDS minD NC_000921.1 342303 343109 D similar to H. pylori 26695 gene HP0331; cell division inhibitor 342303..343109 Helicobacter pylori J99 889358 NP_223034.1 CDS minE NC_000921.1 343106 343339 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 343106..343339 Helicobacter pylori J99 889371 NP_223035.1 CDS jhp0316 NC_000921.1 343351 344151 D similar to H. pylori 26695 gene HP0333; hypothetical protein 343351..344151 Helicobacter pylori J99 889353 NP_223036.1 CDS jhp0317 NC_000921.1 344148 344552 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 344148..344552 Helicobacter pylori J99 889372 NP_223037.1 CDS jhp0318 NC_000921.1 344811 345566 D hypothetical protein 344811..345566 Helicobacter pylori J99 889354 NP_223038.1 CDS jhp0319 NC_000921.1 345751 346089 D similar to H. pylori 26695 gene HP0337; hypothetical protein 345751..346089 Helicobacter pylori J99 889359 NP_223039.1 CDS jhp0320 NC_000921.1 346073 346633 D similar to H. pylori 26695 gene HP0338; hypothetical protein 346073..346633 Helicobacter pylori J99 889363 NP_223040.1 CDS jhp0321 NC_000921.1 346804 347685 R similar to H. pylori 26695 gene HP0347; hypothetical protein complement(346804..347685) Helicobacter pylori J99 889306 NP_223041.1 CDS recJ NC_000921.1 347685 349235 R similar to H. pylori 26695 gene HP0348; single-stranded-DNA-specific exonuclease RECJ complement(347685..349235) Helicobacter pylori J99 889361 NP_223042.1 CDS pyrG NC_000921.1 349245 350861 R CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(349245..350861) Helicobacter pylori J99 889305 NP_223043.1 CDS jhp0324 NC_000921.1 351122 351784 D similar to H. pylori 26695 gene HP0350; hypothetical protein 351122..351784 Helicobacter pylori J99 889330 NP_223044.1 CDS fliF NC_000921.1 351828 353531 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 351828..353531 Helicobacter pylori J99 889326 NP_223045.1 CDS fliG NC_000921.1 353548 354579 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 353548..354579 Helicobacter pylori J99 889342 NP_223046.1 CDS fliH NC_000921.1 354566 355342 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 354566..355342 Helicobacter pylori J99 889325 NP_223047.1 CDS dxs NC_000921.1 355339 357195 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 355339..357195 Helicobacter pylori J99 890336 NP_223048.1 CDS lepA NC_000921.1 357192 359006 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 357192..359006 Helicobacter pylori J99 889348 NP_223049.1 CDS jhp0330 NC_000921.1 359021 359779 D similar to H. pylori 26695 gene HP0356; hypothetical protein 359021..359779 Helicobacter pylori J99 889346 NP_223050.1 CDS jhp0331 NC_000921.1 359722 360018 D hypothetical protein 359722..360018 Helicobacter pylori J99 889351 NP_223051.1 CDS jhp0332 NC_000921.1 360050 360310 D hypothetical protein 360050..360310 Helicobacter pylori J99 890238 NP_223052.1 CDS flgG_1 NC_000921.1 360338 361147 R similar to H. pylori 26695 gene HP1092; flagellar basal-body rod protein complement(360338..361147) Helicobacter pylori J99 890229 NP_223053.1 CDS kgtP NC_000921.1 361203 362516 R similar to H. pylori 26695 gene HP1091; alpha-ketoglutarate permease complement(361203..362516) Helicobacter pylori J99 889332 NP_223054.1 CDS ftsK NC_000921.1 362902 365436 R similar to H. pylori 26695 gene HP1090; septum formation protein complement(362902..365436) Helicobacter pylori J99 890169 NP_223055.1 CDS jhp0336 NC_000921.1 365433 367769 R similar to H. pylori 26695 gene HP1089; hypothetical protein complement(365433..367769) Helicobacter pylori J99 890154 NP_223056.1 CDS tktA NC_000921.1 367766 369691 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(367766..369691) Helicobacter pylori J99 890258 NP_223057.1 CDS ribF NC_000921.1 369738 370580 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(369738..370580) Helicobacter pylori J99 889365 NP_223058.1 CDS hlyA NC_000921.1 370546 371253 R similar to H. pylori 26695 gene HP1086; hemolysin complement(370546..371253) Helicobacter pylori J99 889339 NP_223059.1 CDS jhp0340 NC_000921.1 371253 371762 R similar to H. pylori 26695 gene HP1085; hypothetical protein complement(371253..371762) Helicobacter pylori J99 889117 NP_223060.1 CDS pyrB NC_000921.1 371835 372758 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 371835..372758 Helicobacter pylori J99 889118 NP_223061.1 CDS jhp0342 NC_000921.1 373015 374454 D similar to H. pylori 26695 gene HP1083; hypothetical protein 373015..374454 Helicobacter pylori J99 889122 NP_223062.1 CDS msbA NC_000921.1 374545 376200 D similar to H. pylori 26695 gene HP1082; multi-drug resistance protein 374545..376200 Helicobacter pylori J99 889123 NP_223063.1 CDS jhp0344 NC_000921.1 376194 376817 D similar to H. pylori 26695 gene HP1081; hypothetical protein 376194..376817 Helicobacter pylori J99 889126 NP_223064.1 CDS jhp0345 NC_000921.1 376821 377390 D similar to H. pylori 26695 gene HP1080; hypothetical protein 376821..377390 Helicobacter pylori J99 889129 NP_223065.1 CDS jhp0346 NC_000921.1 377523 378668 D similar to H. pylori 26695 gene HP1079; hypothetical protein 377523..378668 Helicobacter pylori J99 889093 NP_223066.1 CDS jhp0347 NC_000921.1 378854 379357 D similar to H. pylori 26695 gene HP1078; hypothetical protein 378854..379357 Helicobacter pylori J99 889090 NP_223067.1 CDS nixA NC_000921.1 379415 380410 D similar to H. pylori 26695 gene HP1077; high-affinity nickel-transport protein 379415..380410 Helicobacter pylori J99 889097 NP_223068.1 CDS jhp0349 NC_000921.1 380414 380935 R similar to H. pylori 26695 gene HP1076; hypothetical protein complement(380414..380935) Helicobacter pylori J99 889094 NP_223069.1 CDS jhp0350 NC_000921.1 381071 382387 D similar to H. pylori 26695 gene HP1075; hypothetical protein 381071..382387 Helicobacter pylori J99 889100 NP_223070.1 CDS jhp0351 NC_000921.1 382409 383227 R similar to H. pylori 26695 gene HP1074; hypothetical protein complement(382409..383227) Helicobacter pylori J99 889098 NP_223071.1 CDS copP NC_000921.1 383426 383626 R similar to H. pylori 26695 gene HP1073; copper-associated protein complement(383426..383626) Helicobacter pylori J99 889104 NP_223072.1 CDS copA NC_000921.1 383627 385864 R similar to H. pylori 26695 gene HP1072; copper-transporting P-type ATPase complement(383627..385864) Helicobacter pylori J99 889106 NP_223073.1 CDS pssA NC_000921.1 385861 386574 R similar to H. pylori 26695 gene HP1071; phosphatidylserine synthase complement(385861..386574) Helicobacter pylori J99 889108 NP_223074.1 CDS jhp0355 NC_000921.1 386564 386824 R similar to H. pylori 26695 gene HP1070; hypothetical protein complement(386564..386824) Helicobacter pylori J99 889114 NP_223075.1 CDS ftsH_2 NC_000921.1 386827 388725 R similar to H. pylori 26695 gene HP1069; ATP-dependent zinc metallopeptidase complement(386827..388725) Helicobacter pylori J99 889116 NP_223076.1 CDS prmA NC_000921.1 388734 389723 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(388734..389723) Helicobacter pylori J99 888979 NP_223077.1 CDS cheY NC_000921.1 389724 390098 R similar to H. pylori 26695 gene HP1067; response regulator complement(389724..390098) Helicobacter pylori J99 889086 NP_223078.1 CDS jhp0359 NC_000921.1 390392 390994 D similar to H. pylori 26695 gene HP1066; hypothetical protein 390392..390994 Helicobacter pylori J99 888980 NP_223079.1 CDS jhp0360 NC_000921.1 391140 391547 R similar to H. pylori 26695 gene HP1065; hypothetical protein complement(391140..391547) Helicobacter pylori J99 888987 NP_223080.1 CDS jhp0361 NC_000921.1 391550 391843 R similar to H. pylori 26695 gene HP1064; hypothetical protein complement(391550..391843) Helicobacter pylori J99 889069 NP_223081.1 CDS gidB NC_000921.1 391786 392322 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(391786..392322) Helicobacter pylori J99 889261 NP_223082.1 CDS queA NC_000921.1 392319 393356 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(392319..393356) Helicobacter pylori J99 889259 NP_223083.1 CDS jhp0364 NC_000921.1 393357 394106 R similar to H. pylori 26695 gene HP1061; hypothetical protein complement(393357..394106) Helicobacter pylori J99 889360 NP_223084.1 CDS jhp0365 NC_000921.1 394099 394581 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(394099..394581) Helicobacter pylori J99 889275 NP_223085.1 CDS ruvB NC_000921.1 394648 395658 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(394648..395658) Helicobacter pylori J99 889058 NP_223086.1 CDS panB NC_000921.1 395659 396471 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(395659..396471) Helicobacter pylori J99 889082 NP_223087.1 CDS jhp0368 NC_000921.1 396622 397344 D similar to H. pylori 26695 gene HP1057; hypothetical protein 396622..397344 Helicobacter pylori J99 889059 NP_223088.1 CDS jhp0369 NC_000921.1 397322 398191 D similar to H. pylori 26695 gene HP1056; hypothetical protein 397322..398191 Helicobacter pylori J99 889065 NP_223089.1 CDS jhp0370 NC_000921.1 398203 399144 D similar to H. pylori 26695 gene HP1055; hypothetical protein 398203..399144 Helicobacter pylori J99 888977 NP_223090.1 CDS jhp0371 NC_000921.1 399154 400476 D similar to H. pylori 26695 gene HP1054; hypothetical protein 399154..400476 Helicobacter pylori J99 889083 NP_223091.1 CDS minC NC_000921.1 400479 401063 D blocks the formation of polar Z-ring septums; septum formation inhibitor 400479..401063 Helicobacter pylori J99 888971 NP_223092.1 CDS lpxC NC_000921.1 401060 401947 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 401060..401947 Helicobacter pylori J99 889055 NP_223093.1 CDS jhp0374 NC_000921.1 401969 402466 D similar to H. pylori 26695 gene HP1051; hypothetical protein 401969..402466 Helicobacter pylori J99 889036 NP_223094.1 CDS thrB NC_000921.1 402520 403401 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 402520..403401 Helicobacter pylori J99 889035 NP_223095.1 CDS jhp0376 NC_000921.1 403373 403642 D similar to H. pylori 26695 gene HP1049; hypothetical protein 403373..403642 Helicobacter pylori J99 889031 NP_223096.1 CDS infB NC_000921.1 403639 406488 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 403639..406488 Helicobacter pylori J99 889030 NP_223097.1 CDS rbfA NC_000921.1 406488 406823 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 406488..406823 Helicobacter pylori J99 889024 NP_223098.1 CDS jhp0379 NC_000921.1 406816 407256 D similar to H. pylori 26695 gene HP1046; hypothetical protein 406816..407256 Helicobacter pylori J99 889087 NP_223099.1 CDS jhp0380 NC_000921.1 407417 408529 D similar to H. pylori 26695 gene HP1044; hypothetical protein 407417..408529 Helicobacter pylori J99 889130 NP_223100.1 CDS jhp0381 NC_000921.1 408882 409553 D similar to H. pylori 26695 gene HP1043; transcriptional regulator 408882..409553 Helicobacter pylori J99 889131 NP_223101.1 CDS jhp0382 NC_000921.1 410346 411389 R similar to H. pylori 26695 gene HP1042; hypothetical protein complement(410346..411389) Helicobacter pylori J99 889132 NP_223102.1 CDS flhA NC_000921.1 411423 413624 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(411423..413624) Helicobacter pylori J99 889133 NP_223103.1 CDS rpsO NC_000921.1 413760 414032 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 413760..414032 Helicobacter pylori J99 889136 NP_223104.1 CDS jhp0385 NC_000921.1 414088 415377 D similar to H. pylori 26695 gene HP1039; hypothetical protein 414088..415377 Helicobacter pylori J99 889141 NP_223105.1 CDS aroD NC_000921.1 415490 416002 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 415490..416002 Helicobacter pylori J99 889144 NP_223106.1 CDS pepQ NC_000921.1 416015 417088 D similar to H. pylori 26695 gene HP1037; proline peptidase 416015..417088 Helicobacter pylori J99 889146 NP_223107.1 CDS folK NC_000921.1 417085 417576 D similar to H. pylori 26695 gene HP1036; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 417085..417576 Helicobacter pylori J99 889149 NP_223108.1 CDS flhF NC_000921.1 417573 418940 D positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 417573..418940 Helicobacter pylori J99 889152 NP_223109.1 CDS jhp0390 NC_000921.1 418937 419821 D similar to H. pylori 26695 gene HP1034; hypothetical protein 418937..419821 Helicobacter pylori J99 889173 NP_223110.1 CDS jhp0391 NC_000921.1 419834 420109 R similar to H. pylori 26695 gene HP1033; hypothetical protein complement(419834..420109) Helicobacter pylori J99 889176 NP_223111.1 CDS fliA NC_000921.1 420118 420885 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 420118..420885 Helicobacter pylori J99 889178 NP_223112.1 CDS fliM NC_000921.1 420878 421942 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 420878..421942 Helicobacter pylori J99 889210 NP_223113.1 CDS jhp0394 NC_000921.1 421946 422803 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 421946..422803 Helicobacter pylori J99 889271 NP_223114.1 CDS jhp0395 NC_000921.1 422833 423369 D similar to H. pylori 26695 gene HP1029; hypothetical protein 422833..423369 Helicobacter pylori J99 889272 NP_223115.1 CDS jhp0396 NC_000921.1 423366 423869 D similar to H. pylori 26695 gene HP1028; hypothetical protein 423366..423869 Helicobacter pylori J99 889273 NP_223116.1 CDS fur NC_000921.1 423889 424341 R similar to H. pylori 26695 gene HP1027; ferric uptake regulation protein complement(423889..424341) Helicobacter pylori J99 889274 NP_223117.1 CDS jhp0398 NC_000921.1 424501 425676 R similar to H. pylori 26695 gene HP1026; recombination factor protein RarA complement(424501..425676) Helicobacter pylori J99 889137 NP_223118.1 CDS jhp0399 NC_000921.1 425673 426044 R similar to H. pylori 26695 gene HP1025; transcriptional regulator complement(425673..426044) Helicobacter pylori J99 889186 NP_223119.1 CDS dnaJ_1 NC_000921.1 426054 426920 R similar to H. pylori 26695 gene HP1024; co-chaperone with DnaK complement(426054..426920) Helicobacter pylori J99 889187 NP_223120.1 CDS jhp0401 NC_000921.1 427088 428338 D similar to H. pylori 26695 gene HP1023; hypothetical protein 427088..428338 Helicobacter pylori J99 888975 NP_223121.1 CDS jhp0402 NC_000921.1 428582 429448 R similar to H. pylori 26695 gene HP1022; hypothetical protein complement(428582..429448) Helicobacter pylori J99 889229 NP_223122.1 CDS jhp0403 NC_000921.1 429669 430565 R similar to H. pylori 26695 gene HP1021; response regulator complement(429669..430565) Helicobacter pylori J99 889215 NP_223123.1 CDS ispDF NC_000921.1 430587 431816 R bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(430587..431816) Helicobacter pylori J99 889224 NP_223124.1 CDS htrA NC_000921.1 431838 433268 R similar to H. pylori 26695 gene HP1019; protease Do complement(431838..433268) Helicobacter pylori J99 889218 NP_223125.1 CDS jhp0406 NC_000921.1 433313 434740 R similar to H. pylori 26695 gene HP1017; amino acid permease complement(433313..434740) Helicobacter pylori J99 889205 NP_223126.1 CDS pgsA NC_000921.1 434936 435538 R similar to H. pylori 26695 gene HP1016; phosphatidylglycerophosphate synthase complement(434936..435538) Helicobacter pylori J99 889203 NP_223127.1 CDS jhp0408 NC_000921.1 435472 436080 R similar to H. pylori 26695 gene HP1015; hypothetical protein complement(435472..436080) Helicobacter pylori J99 889198 NP_223128.1 CDS jhp0409 NC_000921.1 436090 436878 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(436090..436878) Helicobacter pylori J99 889197 NP_223129.1 CDS dapA NC_000921.1 436875 437777 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(436875..437777) Helicobacter pylori J99 889107 NP_223130.1 CDS jhp0411 NC_000921.1 437791 439122 R similar to H. pylori 26695 gene HP1012; zinc protease complement(437791..439122) Helicobacter pylori J99 889194 NP_223131.1 CDS pyrD NC_000921.1 439119 440174 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(439119..440174) Helicobacter pylori J99 889119 NP_223132.1 CDS ppk NC_000921.1 440213 442240 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(440213..442240) Helicobacter pylori J99 889193 NP_223133.1 CDS hsdS_1a NC_000921.1 442888 444117 R type I restriction enzyme specificity subunit complement(442888..444117) Helicobacter pylori J99 889192 NP_223134.1 CDS hsdM_1 NC_000921.1 444110 445741 R similar to H. pylori 26695 gene HP0463; type I restriction enzyme modification subunit complement(444110..445741) Helicobacter pylori J99 889191 NP_223135.1 CDS jhp0417 NC_000921.1 448924 450819 R similar to H. pylori 26695 gene HP0465; hypothetical protein complement(448924..450819) Helicobacter pylori J99 889185 NP_223136.1 CDS jhp0418 NC_000921.1 450844 451611 R similar to H. pylori 26695 gene HP0466; hypothetical protein complement(450844..451611) Helicobacter pylori J99 889181 NP_223137.1 CDS jhp0419 NC_000921.1 451621 451968 R similar to H. pylori 26695 gene HP0467; hypothetical protein complement(451621..451968) Helicobacter pylori J99 889051 NP_223138.1 CDS jhp0420 NC_000921.1 451937 453424 R similar to H. pylori 26695 gene HP0468; hypothetical protein complement(451937..453424) Helicobacter pylori J99 889050 NP_223139.1 CDS jhp0421 NC_000921.1 453436 453924 R similar to H. pylori 26695 gene HP0469; hypothetical protein complement(453436..453924) Helicobacter pylori J99 889040 NP_223140.1 CDS pepF NC_000921.1 453909 455645 R similar to H. pylori 26695 gene HP0470; oligopeptidase complement(453909..455645) Helicobacter pylori J99 889029 NP_223141.1 CDS kefB NC_000921.1 455743 456993 R similar to H. pylori 26695 gene HP0471; glutathione-regulated potassium-efflux system protein complement(455743..456993) Helicobacter pylori J99 889027 NP_223142.1 CDS jhp0424 NC_000921.1 457312 457872 R similar to H. pylori 26695 gene HP0472; hypothetical protein complement(457312..457872) Helicobacter pylori J99 888982 NP_223143.1 CDS modA NC_000921.1 458097 458837 D similar to H. pylori 26695 gene HP0473; molybdate ABC transporter periplasmic-binding protein 458097..458837 Helicobacter pylori J99 888973 NP_223144.1 CDS modB NC_000921.1 458859 459533 D similar to H. pylori 26695 gene HP0474; molybdate ABC transporter permease 458859..459533 Helicobacter pylori J99 888970 NP_223145.1 CDS modC NC_000921.1 459530 460327 D similar to H. pylori 26695 gene HP0475; molybdate ABC transporter ATP-binding protein 459530..460327 Helicobacter pylori J99 888996 NP_223146.1 CDS gltX NC_000921.1 460444 461835 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(460444..461835) Helicobacter pylori J99 888993 NP_223147.1 CDS jhp0429 NC_000921.1 461953 463068 D similar to H. pylori 26695 gene HP0477; hypothetical protein 461953..463068 Helicobacter pylori J99 889014 NP_223148.1 CDS jhp0430 NC_000921.1 463077 464714 D similar to H. pylori 26695 gene HP0478; type II DNA modification (methyltransferase 463077..464714 Helicobacter pylori J99 889039 NP_223149.1 CDS jhp0431 NC_000921.1 464680 465528 D similar to H. pylori 26695 gene HP0479; hypothetical protein 464680..465528 Helicobacter pylori J99 889219 NP_223150.1 CDS jhp0432 NC_000921.1 465574 467373 D similar to H. pylori 26695 gene HP0480; hypothetical protein 465574..467373 Helicobacter pylori J99 889019 NP_223151.1 CDS jhp0433 NC_000921.1 467389 468318 D similar to H. pylori 26695 gene HP0481; type II DNA modification enzyme 467389..468318 Helicobacter pylori J99 889021 NP_223152.1 CDS jhp0434 NC_000921.1 468321 468848 D similar to H. pylori 26695 gene HP0482; hypothetical protein 468321..468848 Helicobacter pylori J99 889245 NP_223153.1 CDS jhp0435 NC_000921.1 469030 470085 D similar to H. pylori 26695 gene HP0483; type II DNA modification (methyltransferase 469030..470085 Helicobacter pylori J99 889077 NP_223154.1 CDS jhp0436 NC_000921.1 470276 470830 D similar to H. pylori 26695 gene HP0484; hypothetical protein 470276..470830 Helicobacter pylori J99 889047 NP_223155.1 CDS jhp0437 NC_000921.1 471069 472013 R similar to H. pylori 26695 gene HP0485; hypothetical protein complement(471069..472013) Helicobacter pylori J99 889216 NP_223156.1 CDS jhp0438 NC_000921.1 472290 473876 D similar to H. pylori 26695 gene HP0486; hypothetical protein 472290..473876 Helicobacter pylori J99 889042 NP_223157.1 CDS jhp0439 NC_000921.1 473948 475345 D similar to H. pylori 26695 gene HP0487; hypothetical protein 473948..475345 Helicobacter pylori J99 889032 NP_223158.1 CDS jhp0440 NC_000921.1 475860 478598 D similar to H. pylori 26695 gene HP0488; hypothetical protein 475860..478598 Helicobacter pylori J99 889079 NP_223159.1 CDS jhp0441 NC_000921.1 478667 479212 D similar to H. pylori 26695 gene HP0489; hypothetical protein 478667..479212 Helicobacter pylori J99 889044 NP_223160.1 CDS jhp0442 NC_000921.1 479452 480588 R similar to H. pylori 26695 gene HP0490; potassium channel protein complement(479452..480588) Helicobacter pylori J99 889214 NP_223161.1 CDS rpmB NC_000921.1 480775 480963 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(480775..480963) Helicobacter pylori J99 889046 NP_223162.1 CDS jhp0444 NC_000921.1 481063 481911 R similar to H. pylori 26695 gene HP0492; paralog of HpaA complement(481063..481911) Helicobacter pylori J99 889171 NP_223163.1 CDS mraY NC_000921.1 482029 483090 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 482029..483090 Helicobacter pylori J99 889041 NP_223164.1 CDS murD NC_000921.1 483092 484360 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 483092..484360 Helicobacter pylori J99 889170 NP_223165.1 CDS jhp0447 NC_000921.1 484357 484617 R similar to H. pylori 26695 gene HP0495; hypothetical protein complement(484357..484617) Helicobacter pylori J99 889052 NP_223166.1 CDS jhp0448 NC_000921.1 484607 485008 R similar to H. pylori 26695 gene HP0496; hypothetical protein complement(484607..485008) Helicobacter pylori J99 889175 NP_223167.1 CDS jhp0449 NC_000921.1 485240 486568 D similar to H. pylori 26695 gene HP0497; transporter 485240..486568 Helicobacter pylori J99 889053 NP_223168.1 CDS jhp0450 NC_000921.1 486579 487907 D similar to H. pylori 26695 gene HP0498; transporter 486579..487907 Helicobacter pylori J99 889166 NP_223169.1 CDS pldA NC_000921.1 487922 488989 D similar to H. pylori 26695 gene HP0499; phospholipase A1 487922..488989 Helicobacter pylori J99 889048 NP_223170.1 CDS dnaN NC_000921.1 489047 490171 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 489047..490171 Helicobacter pylori J99 889001 NP_223171.1 CDS gyrB NC_000921.1 490184 492505 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 490184..492505 Helicobacter pylori J99 889037 NP_223172.1 CDS jhp0454 NC_000921.1 492512 493543 D similar to H. pylori 26695 gene HP0502 and HP0503; hypothetical protein 492512..493543 Helicobacter pylori J99 889078 NP_223173.1 CDS jhp0455 NC_000921.1 493530 494285 D similar to H. pylori 26695 gene HP0504 and HP0505; hypothetical protein 493530..494285 Helicobacter pylori J99 889016 NP_223174.1 CDS jhp0456 NC_000921.1 494500 495720 D similar to H. pylori 26695 gene HP0506; hypothetical protein 494500..495720 Helicobacter pylori J99 889015 NP_223175.1 CDS jhp0457 NC_000921.1 495720 496358 D similar to H. pylori 26695 gene HP0507; hypothetical protein 495720..496358 Helicobacter pylori J99 889061 NP_223176.1 CDS jhp0458 NC_000921.1 496369 497721 D similar to H. pylori 26695 gene HP0508; hypothetical protein 496369..497721 Helicobacter pylori J99 889006 NP_223177.1 CDS glcD NC_000921.1 497726 499105 D similar to H. pylori 26695 gene HP0509; glycolate oxidase 497726..499105 Helicobacter pylori J99 889043 NP_223178.1 CDS dapB NC_000921.1 499128 499892 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 499128..499892 Helicobacter pylori J99 888994 NP_223179.1 CDS glnA NC_000921.1 501230 502675 R similar to H. pylori 26695 gene HP0512; glutamine synthetase complement(501230..502675) Helicobacter pylori J99 889208 NP_223180.1 CDS jhp0462 NC_000921.1 502813 504933 D similar to H. pylori 26695 gene HP0513; hypothetical protein 502813..504933 Helicobacter pylori J99 889200 NP_223181.1 CDS rplI NC_000921.1 504996 505445 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 504996..505445 Helicobacter pylori J99 889188 NP_223182.1 CDS hslV NC_000921.1 505449 505991 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 505449..505991 Helicobacter pylori J99 889221 NP_223183.1 CDS hslU NC_000921.1 505991 507322 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 505991..507322 Helicobacter pylori J99 889220 NP_223184.1 CDS era NC_000921.1 507322 508227 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 507322..508227 Helicobacter pylori J99 889212 NP_223185.1 CDS jhp0467 NC_000921.1 508224 509216 D similar to H. pylori 26695 gene HP0518; hypothetical protein 508224..509216 Helicobacter pylori J99 889226 NP_223186.1 CDS jhp0468 NC_000921.1 509304 510155 R similar to H. pylori 26695 gene HP0519; hypothetical protein complement(509304..510155) Helicobacter pylori J99 889225 NP_223187.1 CDS orf6 NC_000921.1 510500 510847 D similar to H. pylori 26695 gene HP0520; cag island protein 510500..510847 Helicobacter pylori J99 889223 NP_223188.1 CDS orf7 NC_000921.1 510990 511649 D similar to H. pylori 26695 gene HP0521; cag island protein 510990..511649 Helicobacter pylori J99 889232 NP_223189.1 CDS orf8 NC_000921.1 511642 513087 D similar to H. pylori 26695 gene HP0522; cag island protein 511642..513087 Helicobacter pylori J99 889230 NP_223190.1 CDS orf9 NC_000921.1 513097 513606 D similar to H. pylori 26695 gene HP0523; cag island protein 513097..513606 Helicobacter pylori J99 889228 NP_223191.1 CDS virD4 NC_000921.1 514088 516334 R similar to H. pylori 26695 gene HP0524; cag island protein, DNA transfer protein complement(514088..516334) Helicobacter pylori J99 889145 NP_223192.1 CDS virB11_1 NC_000921.1 516343 517335 R similar to H. pylori 26695 gene HP0525; cag island protein, DNA transfer protein complement(516343..517335) Helicobacter pylori J99 889095 NP_223193.1 CDS orf12 NC_000921.1 517340 517939 R similar to H. pylori 26695 gene HP0526; cag island protein complement(517340..517939) Helicobacter pylori J99 889246 NP_223194.1 CDS orf13/14 NC_000921.1 518074 523533 R similar to H. pylori 26695 gene HP0527; cag island protein complement(518074..523533) Helicobacter pylori J99 889142 NP_223195.1 CDS orf15 NC_000921.1 523548 525116 R similar to H. pylori 26695 gene HP0528; cag island protein complement(523548..525116) Helicobacter pylori J99 889138 NP_223196.1 CDS orf16 NC_000921.1 525169 526776 R similar to H. pylori 26695 gene HP0529; cag island protein complement(525169..526776) Helicobacter pylori J99 889143 NP_223197.1 CDS orf17 NC_000921.1 526781 527539 R similar to H. pylori 26695 gene HP0530; cag island protein complement(526781..527539) Helicobacter pylori J99 889238 NP_223198.1 CDS orf18 NC_000921.1 527921 528577 D similar to H. pylori 26695 gene HP0531; cag island protein 527921..528577 Helicobacter pylori J99 889233 NP_223199.1 CDS cagT NC_000921.1 528613 529455 D similar to H. pylori 26695 gene HP0532; cag island protein 528613..529455 Helicobacter pylori J99 889235 NP_223200.1 CDS cagS NC_000921.1 529660 530259 R similar to H. pylori 26695 gene HP0534; cag island protein complement(529660..530259) Helicobacter pylori J99 888988 NP_223201.1 CDS cagQ NC_000921.1 530698 531078 R similar to H. pylori 26695 gene HP0535; cag island protein complement(530698..531078) Helicobacter pylori J99 889234 NP_223202.1 CDS cagP NC_000921.1 531505 531849 R similar to H. pylori 26695 gene HP0536; cag island protein complement(531505..531849) Helicobacter pylori J99 889236 NP_223203.1 CDS cagM NC_000921.1 532464 533594 D similar to H. pylori 26695 gene HP0537; cag island protein 532464..533594 Helicobacter pylori J99 889009 NP_223204.1 CDS cagN NC_000921.1 533609 534529 D similar to H. pylori 26695 gene HP0538; cag island protein 533609..534529 Helicobacter pylori J99 889196 NP_223205.1 CDS cagL NC_000921.1 534611 535324 R similar to H. pylori 26695 gene HP0539; cag island protein complement(534611..535324) Helicobacter pylori J99 888972 NP_223206.1 CDS cagI NC_000921.1 535321 536466 R similar to H. pylori 26695 gene HP0540; cag island protein complement(535321..536466) Helicobacter pylori J99 889182 NP_223207.1 CDS cagH NC_000921.1 536477 537589 R similar to H. pylori 26695 gene HP0541; cag island protein complement(536477..537589) Helicobacter pylori J99 888978 NP_223208.1 CDS cagG NC_000921.1 537606 538034 R similar to H. pylori 26695 gene HP0542; cag island protein complement(537606..538034) Helicobacter pylori J99 889000 NP_223209.1 CDS cagF NC_000921.1 538089 538895 R similar to H. pylori 26695 gene HP0543; cag island protein complement(538089..538895) Helicobacter pylori J99 889180 NP_223210.1 CDS cagE NC_000921.1 538897 541848 R similar to H. pylori 26695 gene HP0544; DNA transfer protein complement(538897..541848) Helicobacter pylori J99 888976 NP_223211.1 CDS cagD NC_000921.1 541857 542483 R similar to H. pylori 26695 gene HP0545; cag island protein complement(541857..542483) Helicobacter pylori J99 889045 NP_223212.1 CDS cagC NC_000921.1 542485 542832 R similar to H. pylori 26695 gene HP0546; cag island protein complement(542485..542832) Helicobacter pylori J99 889049 NP_223213.1 CDS cagA NC_000921.1 543605 547108 D similar to H. pylori 26695 gene HP0547; cag island protein, cytotoxicity associated immunodominant antigen 543605..547108 Helicobacter pylori J99 889201 NP_223214.1 CDS murI NC_000921.1 547927 548694 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(547927..548694) Helicobacter pylori J99 889183 NP_223215.1 CDS rho NC_000921.1 548734 550050 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(548734..550050) Helicobacter pylori J99 889207 NP_223216.1 CDS rpmE NC_000921.1 550315 550518 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 550315..550518 Helicobacter pylori J99 889159 NP_223217.1 CDS jhp0499 NC_000921.1 550542 551411 D similar to H. pylori 26695 gene HP0552; hypothetical protein 550542..551411 Helicobacter pylori J99 889204 NP_223218.1 CDS jhp0500 NC_000921.1 551425 552108 D similar to H. pylori 26695 gene HP0553; hypothetical protein 551425..552108 Helicobacter pylori J99 889067 NP_223219.1 CDS jhp0501 NC_000921.1 552121 553086 D similar to H. pylori 26695 gene HP0554; hypothetical protein 552121..553086 Helicobacter pylori J99 889140 NP_223220.1 CDS jhp0502 NC_000921.1 553083 553904 D similar to H. pylori 26695 gene HP0555; hypothetical protein 553083..553904 Helicobacter pylori J99 888997 NP_223221.1 CDS jhp0503 NC_000921.1 553975 554412 R similar to H. pylori 26695 gene HP0556; hypothetical protein complement(553975..554412) Helicobacter pylori J99 889101 NP_223222.1 CDS accA NC_000921.1 554894 555832 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(554894..555832) Helicobacter pylori J99 889268 NP_223223.1 CDS fabB NC_000921.1 555854 557092 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(555854..557092) Helicobacter pylori J99 889109 NP_223224.1 CDS acpP NC_000921.1 557195 557431 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(557195..557431) Helicobacter pylori J99 889121 NP_223226.1 CDS fabG NC_000921.1 557662 558405 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(557662..558405) Helicobacter pylori J99 889148 NP_223227.1 CDS rpsU NC_000921.1 558444 558656 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(558444..558656) Helicobacter pylori J99 889020 NP_223228.1 CDS jhp0510 NC_000921.1 558757 560007 R similar to H. pylori 26695 gene HP0563; hypothetical protein complement(558757..560007) Helicobacter pylori J99 889135 NP_223229.1 CDS jhp0511 NC_000921.1 560181 560426 D similar to H. pylori 26695 gene HP0564; hypothetical protein 560181..560426 Helicobacter pylori J99 889113 NP_223230.1 CDS jhp0512 NC_000921.1 560450 561097 R similar to H. pylori 26695 gene HP0565; hypothetical protein complement(560450..561097) Helicobacter pylori J99 889096 NP_223231.1 CDS dapF NC_000921.1 561210 562031 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(561210..562031) Helicobacter pylori J99 889270 NP_223232.1 CDS jhp0514 NC_000921.1 562146 563195 D similar to H. pylori 26695 gene HP0567; hypothetical protein 562146..563195 Helicobacter pylori J99 889128 NP_223233.1 CDS jhp0515 NC_000921.1 563901 564668 R similar to H. pylori 26695 gene HP0568; hypothetical protein complement(563901..564668) Helicobacter pylori J99 889070 NP_223234.1 CDS jhp0516 NC_000921.1 564812 565912 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(564812..565912) Helicobacter pylori J99 889111 NP_223235.1 CDS pepA NC_000921.1 565914 567404 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(565914..567404) Helicobacter pylori J99 889103 NP_223236.1 CDS jhp0518 NC_000921.1 567452 568030 R similar to H. pylori 26695 gene HP0571; hypothetical protein complement(567452..568030) Helicobacter pylori J99 889099 NP_223237.1 CDS apt NC_000921.1 568045 568584 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(568045..568584) Helicobacter pylori J99 889153 NP_223238.1 CDS jhp0520 NC_000921.1 568645 568977 R similar to H. pylori 26695 gene HP0573; hypothetical protein complement(568645..568977) Helicobacter pylori J99 889115 NP_223239.1 CDS rpi NC_000921.1 569028 569483 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(569028..569483) Helicobacter pylori J99 889110 NP_223240.1 CDS jhp0522 NC_000921.1 569502 570200 R similar to H. pylori 26695 gene HP0575; hypothetical protein complement(569502..570200) Helicobacter pylori J99 889072 NP_223241.1 CDS lepB NC_000921.1 570209 571081 R similar to H. pylori 26695 gene HP0576; signal peptidase I complement(570209..571081) Helicobacter pylori J99 889013 NP_223242.1 CDS folD NC_000921.1 571081 571953 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(571081..571953) Helicobacter pylori J99 889062 NP_223243.1 CDS jhp0525 NC_000921.1 572039 574075 R similar to H. pylori 26695 gene HP0578; hypothetical protein complement(572039..574075) Helicobacter pylori J99 889018 NP_223244.1 CDS jhp0526 NC_000921.1 574084 574635 R similar to H. pylori 26695 gene HP0579; hypothetical protein complement(574084..574635) Helicobacter pylori J99 889150 NP_223245.1 CDS jhp0527 NC_000921.1 574642 575760 R similar to H. pylori 26695 gene HP0580; hypothetical protein complement(574642..575760) Helicobacter pylori J99 888992 NP_223246.1 CDS pyrC_2 NC_000921.1 575736 576755 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(575736..576755) Helicobacter pylori J99 889156 NP_223247.1 CDS tonB_1 NC_000921.1 576760 577713 R similar to H. pylori 26695 gene HP0582; siderophore-mediated IRON transport protein complement(576760..577713) Helicobacter pylori J99 889147 NP_223248.1 CDS jhp0530 NC_000921.1 577697 578578 R similar to H. pylori 26695 gene HP0583; hypothetical protein complement(577697..578578) Helicobacter pylori J99 889124 NP_223249.1 CDS fliN NC_000921.1 578575 578946 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein complement(578575..578946) Helicobacter pylori J99 889125 NP_223250.1 CDS nth NC_000921.1 579028 579672 R similar to H. pylori 26695 gene HP0585; endonuclease III complement(579028..579672) Helicobacter pylori J99 889127 NP_223251.1 CDS jhp0533 NC_000921.1 579669 579905 R hypothetical protein complement(579669..579905) Helicobacter pylori J99 889134 NP_223252.1 CDS jhp0534 NC_000921.1 579902 582838 R similar to H. pylori 26695 gene HP0586; hypothetical protein complement(579902..582838) Helicobacter pylori J99 889012 NP_223253.1 CDS jhp0535 NC_000921.1 582756 583745 D similar to H. pylori 26695 gene HP0587; hypothetical protein 582756..583745 Helicobacter pylori J99 888990 NP_223254.1 CDS oorD NC_000921.1 583930 584271 D similar to H. pylori 26695 gene HP0588; 2-oxoglutarate-acceptor oxidoreductase subunit OorD 583930..584271 Helicobacter pylori J99 889073 NP_223255.1 CDS oorA NC_000921.1 584271 585398 D Couples the complete acetyl-CoA oxidation to aromatic ring reduction by the use of the low-potential electron shuttle ferredoxin; 2-oxoglutarate-acceptor oxidoreductase subunit OorA 584271..585398 Helicobacter pylori J99 889060 NP_223256.1 CDS oorB NC_000921.1 585400 586221 D Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin; 2-oxoglutarate-acceptor oxidoreductase subunit OorB 585400..586221 Helicobacter pylori J99 889085 NP_223257.1 CDS oorC NC_000921.1 586221 586775 D Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; 2-oxoglutarate-acceptor oxidoreductase subunit OorC 586221..586775 Helicobacter pylori J99 889088 NP_223258.1 CDS jhp0540 NC_000921.1 586889 588664 D hypothetical protein 586889..588664 Helicobacter pylori J99 889102 NP_223259.1 CDS jhp0541 NC_000921.1 588823 588987 D similar to H. pylori 26695 gene HP0594; hypothetical protein 588823..588987 Helicobacter pylori J99 889089 NP_223260.1 CDS jhp0542 NC_000921.1 588997 590469 D similar to H. pylori 26695 gene HP0595; hypothetical protein 588997..590469 Helicobacter pylori J99 889112 NP_223261.1 CDS jhp0543 NC_000921.1 590938 591516 D Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein 590938..591516 Helicobacter pylori J99 889164 NP_223262.1 CDS jhp0544 NC_000921.1 591519 593501 R similar to H. pylori 26695 gene HP0597; penicillin-binding protein complement(591519..593501) Helicobacter pylori J99 889120 NP_223263.1 CDS bioF NC_000921.1 593501 594622 R similar to H. pylori 26695 gene HP0598; 8-amino-7-oxononanoate synthase complement(593501..594622) Helicobacter pylori J99 889163 NP_223264.1 CDS jhp0546 NC_000921.1 594645 595946 R similar to H. pylori 26695 gene HP0599; methyl-accepting chemotaxis protein (MCP) complement(594645..595946) Helicobacter pylori J99 889169 NP_223265.1 CDS jhp0547 NC_000921.1 596018 597787 R similar to H. pylori 26695 gene HP0600; secretion/efflux ABC transporter ATP-binding protein complement(596018..597787) Helicobacter pylori J99 888995 NP_223266.1 CDS flaA NC_000921.1 597954 599486 D FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A 597954..599486 Helicobacter pylori J99 889160 NP_223267.1 CDS jhp0549 NC_000921.1 599604 600260 D similar to H. pylori 26695 gene HP0602; 3-methyladenine DNA glycosylase 599604..600260 Helicobacter pylori J99 888986 NP_223268.1 CDS jhp0550 NC_000921.1 600257 600874 D similar to H. pylori 26695 gene HP0603; hypothetical protein 600257..600874 Helicobacter pylori J99 889177 NP_223269.1 CDS hemE NC_000921.1 600943 601962 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 600943..601962 Helicobacter pylori J99 889017 NP_223270.1 CDS jhp0552 NC_000921.1 601972 603405 D similar to H. pylori 26695 gene HP0605; hypothetical protein 601972..603405 Helicobacter pylori J99 889074 NP_223271.1 CDS jhp0553 NC_000921.1 603416 604120 D similar to H. pylori 26695 gene HP0606; efflux transporter 603416..604120 Helicobacter pylori J99 889063 NP_223272.1 CDS jhp0554 NC_000921.1 604133 607219 D similar to H. pylori 26695 gene HP0607; efflux transporter 604133..607219 Helicobacter pylori J99 889022 NP_223273.1 CDS jhp0555 NC_000921.1 607216 607785 D similar to H. pylori 26695 gene HP0608; hypothetical protein 607216..607785 Helicobacter pylori J99 889034 NP_223274.1 CDS jhp0556 NC_000921.1 607948 617532 D similar to H. pylori 26695 gene HP0609 and HP0610; vacuolating cytotoxin (VacA) paralog 607948..617532 Helicobacter pylori J99 889167 NP_223275.1 CDS jhp0557 NC_000921.1 618350 618682 R similar to H. pylori 26695 gene HP0614; hypothetical protein complement(618350..618682) Helicobacter pylori J99 889206 NP_223276.1 CDS ligA NC_000921.1 618855 620825 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(618855..620825) Helicobacter pylori J99 889265 NP_223277.1 CDS cheV_2 NC_000921.1 620896 621837 D similar to H. pylori 26695 gene HP0616; chemotaxis protein 620896..621837 Helicobacter pylori J99 889264 NP_223278.1 CDS aspS NC_000921.1 621872 623611 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 621872..623611 Helicobacter pylori J99 889250 NP_223279.1 CDS adk NC_000921.1 623623 624198 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 623623..624198 Helicobacter pylori J99 889263 NP_223280.1 CDS jhp0562 NC_000921.1 624223 625221 D lipopolysaccharide biosynthesis protein 624223..625221 Helicobacter pylori J99 889251 NP_223281.1 CDS jhp0563 NC_000921.1 625240 626575 D similar to TIGR HP0619; expression of this protein is predicted to be regulated by slipped-strand repair at the (C) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; lipopolysaccharide biosynthesis protein join(625240..625777,625779..626575) Helicobacter pylori J99 890353 NP_223282.1 CDS ppa NC_000921.1 626631 627152 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 626631..627152 Helicobacter pylori J99 890356 NP_223283.1 CDS mutS NC_000921.1 627301 629589 R MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein complement(627301..629589) Helicobacter pylori J99 890351 NP_223284.1 CDS jhp0566 NC_000921.1 629550 629912 R similar to H. pylori 26695 gene HP0622; hypothetical protein complement(629550..629912) Helicobacter pylori J99 890354 NP_223285.1 CDS murC NC_000921.1 629912 631261 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(629912..631261) Helicobacter pylori J99 890352 NP_223286.1 CDS jhp0568 NC_000921.1 631254 632381 R similar to H. pylori 26695 gene HP0624; hypothetical protein complement(631254..632381) Helicobacter pylori J99 890350 NP_223287.1 CDS ispG NC_000921.1 632534 633613 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 632534..633613 Helicobacter pylori J99 890349 NP_223288.1 CDS dapD NC_000921.1 633616 634821 D similar to H. pylori 26695 gene HP0626; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 633616..634821 Helicobacter pylori J99 890348 NP_223289.1 CDS jhp0571 NC_000921.1 634833 635891 D similar to H. pylori 26695 gene HP0627 and HP0628; hypothetical protein 634833..635891 Helicobacter pylori J99 890347 NP_223290.1 CDS jhp0572 NC_000921.1 636104 638155 D similar to H. pylori 26695 gene HP0629; hypothetical protein 636104..638155 Helicobacter pylori J99 890346 NP_223291.1 CDS jhp0573 NC_000921.1 638201 638785 R similar to H. pylori 26695 gene HP0630; hypothetical protein complement(638201..638785) Helicobacter pylori J99 890345 NP_223292.1 CDS hyaA NC_000921.1 638943 640097 D similar to H. pylori 26695 gene HP0631; hydrogenase, small subunit 638943..640097 Helicobacter pylori J99 890344 NP_223293.1 CDS hyaB NC_000921.1 640107 641843 D similar to H. pylori 26695 gene HP0632; hydrogenase, large subunit 640107..641843 Helicobacter pylori J99 890341 NP_223294.1 CDS hyaC NC_000921.1 641856 642530 D similar to H. pylori 26695 gene HP0633; hydrogenase, cytochrome subunit 641856..642530 Helicobacter pylori J99 890342 NP_223295.1 CDS hyaD NC_000921.1 642527 643063 D similar to H. pylori 26695 gene HP0634; hydrogenase expression/formation protein 642527..643063 Helicobacter pylori J99 890343 NP_223296.1 CDS jhp0578 NC_000921.1 643065 644603 D similar to H. pylori 26695 gene HP0635; hypothetical protein 643065..644603 Helicobacter pylori J99 890337 NP_223297.1 CDS jhp0579 NC_000921.1 644608 645021 R similar to H. pylori 26695 gene HP0636; hypothetical protein complement(644608..645021) Helicobacter pylori J99 890340 NP_223298.1 CDS jhp0580 NC_000921.1 645140 645592 R similar to H. pylori 26695 gene HP0637; hypothetical protein complement(645140..645592) Helicobacter pylori J99 890339 NP_223299.1 CDS jhp0581 NC_000921.1 645773 646696 D similar to H. pylori 26695 gene HP0638; hypothetical protein 645773..646696 Helicobacter pylori J99 890338 NP_223300.1 CDS jhp0582 NC_000921.1 646935 647612 R similar to H. pylori 26695 gene HP0639; hypothetical protein complement(646935..647612) Helicobacter pylori J99 890330 NP_223301.1 CDS pcnB NC_000921.1 647674 648882 D similar to H. pylori 26695 gene HP0640; polynucleotide adenylyltransferase 647674..648882 Helicobacter pylori J99 890335 NP_223302.1 CDS jhp0584 NC_000921.1 648903 649406 D similar to H. pylori 26695 gene HP0641; hypothetical protein 648903..649406 Helicobacter pylori J99 890333 NP_223303.1 CDS jhp0585 NC_000921.1 649421 650278 D 3-hydroxyacid dehydrogenase 649421..650278 Helicobacter pylori J99 890332 NP_223304.1 CDS jhp0586 NC_000921.1 650280 650933 D similar to H. pylori 26695 gene HP0642; NAD(P)H-flavin oxidoreductase 650280..650933 Helicobacter pylori J99 890331 NP_223305.1 CDS jhp0587 NC_000921.1 650990 651229 R hypothetical protein complement(650990..651229) Helicobacter pylori J99 890329 NP_223306.1 CDS gltX NC_000921.1 651258 652577 D charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase 651258..652577 Helicobacter pylori J99 890324 NP_223307.1 CDS jhp0589 NC_000921.1 652574 652867 D similar to H. pylori 26695 gene HP0644; hypothetical protein 652574..652867 Helicobacter pylori J99 890327 NP_223308.1 CDS jhp0590 NC_000921.1 652876 654558 D similar to H. pylori 26695 gene HP0645; lytic murein transglycosylase 652876..654558 Helicobacter pylori J99 890325 NP_223309.1 CDS galU NC_000921.1 654555 655376 D similar to H. pylori 26695 gene HP0646; UTP-glucose-1-phosphate uridylyltransferase 654555..655376 Helicobacter pylori J99 890326 NP_223310.1 CDS jhp0592 NC_000921.1 655388 655795 D similar to H. pylori 26695 gene HP0647; hypothetical protein 655388..655795 Helicobacter pylori J99 890322 NP_223311.1 CDS murA NC_000921.1 655798 657066 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 655798..657066 Helicobacter pylori J99 890317 NP_223312.1 CDS aspA NC_000921.1 657124 658530 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 657124..658530 Helicobacter pylori J99 890323 NP_223313.1 CDS jhp0595 NC_000921.1 658536 659165 D similar to H. pylori 26695 gene HP0650; hypothetical protein 658536..659165 Helicobacter pylori J99 890320 NP_223314.1 CDS fucT NC_000921.1 659174 660538 R similar to H. pylori 26695 gene HP0651; alpha (1,3)-fucosyltransferase complement(659174..660538) Helicobacter pylori J99 890321 NP_223315.1 CDS serB NC_000921.1 660576 661199 R similar to H. pylori 26695 gene HP0652; phosphoserine phosphatase complement(660576..661199) Helicobacter pylori J99 890318 NP_223316.1 CDS pfr NC_000921.1 661214 661717 R similar to H. pylori 26695 gene HP0653; nonheme iron-containing ferritin complement(661214..661717) Helicobacter pylori J99 890319 NP_223317.1 CDS jhp0599 NC_000921.1 662016 663098 D similar to H. pylori 26695 gene HP0654; hypothetical protein 662016..663098 Helicobacter pylori J99 890304 NP_223318.1 CDS jhp0600 NC_000921.1 663181 665901 D similar to H. pylori 26695 gene HP0655; protective surface antigen D15 663181..665901 Helicobacter pylori J99 890316 NP_223319.1 CDS jhp0601 NC_000921.1 665903 666964 D similar to H. pylori 26695 gene HP0656; hypothetical protein 665903..666964 Helicobacter pylori J99 890313 NP_223320.1 CDS jhp0602 NC_000921.1 666970 668277 D similar to H. pylori 26695 gene HP0657; processing protease 666970..668277 Helicobacter pylori J99 890315 NP_223321.1 CDS gatB NC_000921.1 668277 669701 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 668277..669701 Helicobacter pylori J99 890314 NP_223322.1 CDS jhp0604 NC_000921.1 669701 670942 D similar to H. pylori 26695 gene HP0659; hypothetical protein 669701..670942 Helicobacter pylori J99 890312 NP_223323.1 CDS jhp0605 NC_000921.1 670952 671959 D similar to H. pylori 26695 gene HP0660; hypothetical protein 670952..671959 Helicobacter pylori J99 890310 NP_223324.1 CDS rnhA NC_000921.1 671961 672392 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 671961..672392 Helicobacter pylori J99 890309 NP_223325.1 CDS rnc NC_000921.1 672404 673123 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 672404..673123 Helicobacter pylori J99 890308 NP_223326.1 CDS aroC NC_000921.1 673120 674217 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 673120..674217 Helicobacter pylori J99 890307 NP_223327.1 CDS jhp0609 NC_000921.1 674254 674769 D similar to H. pylori 26695 gene HP0664; hypothetical protein 674254..674769 Helicobacter pylori J99 890306 NP_223328.1 CDS hemN_1 NC_000921.1 674769 676142 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 674769..676142 Helicobacter pylori J99 890302 NP_223329.1 CDS glpC NC_000921.1 676139 677440 D similar to H. pylori 26695 gene HP0666; glycerol-3-phosphate dehydrogenase 676139..677440 Helicobacter pylori J99 890303 NP_223330.1 CDS jhp0612 NC_000921.1 677518 678870 D similar to H. pylori 26695 gene HP0667 and HP0668; hypothetical protein 677518..678870 Helicobacter pylori J99 890301 NP_223331.1 CDS jhp0613 NC_000921.1 678872 682375 D similar to H. pylori 26695 gene HP0669; hypothetical protein 678872..682375 Helicobacter pylori J99 890299 NP_223332.1 CDS jhp0614 NC_000921.1 682624 683436 D similar to H. pylori 26695 gene HP0671; hypothetical protein 682624..683436 Helicobacter pylori J99 890300 NP_223333.1 CDS aspB NC_000921.1 683596 684768 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 683596..684768 Helicobacter pylori J99 890295 NP_223334.1 CDS jhp0616 NC_000921.1 684935 685726 D hypothetical protein 684935..685726 Helicobacter pylori J99 890298 NP_223335.1 CDS jhp0617 NC_000921.1 685741 686811 D similar to H. pylori 26695 gene HP0675; integrase-recombinase (XERCD family) 685741..686811 Helicobacter pylori J99 890296 NP_223336.1 CDS ogt NC_000921.1 686875 687381 R similar to H. pylori 26695 gene HP0676; methylated-DNA--protein-cysteine methyltransferase complement(686875..687381) Helicobacter pylori J99 890297 NP_223337.1 CDS jhp0619 NC_000921.1 687381 688148 R similar to H. pylori 26695 gene HP0677; hypothetical protein complement(687381..688148) Helicobacter pylori J99 890286 NP_223338.1 CDS jhp0620 NC_000921.1 688273 689220 R similar to H. pylori 26695 gene HP0679; lipopolysaccharide biosynthesis protein complement(688273..689220) Helicobacter pylori J99 890293 NP_223339.1 CDS nrdA NC_000921.1 689282 691648 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(689282..691648) Helicobacter pylori J99 890291 NP_223340.1 CDS jhp0622 NC_000921.1 691820 692326 R similar to H. pylori 26695 gene HP0681; hypothetical protein complement(691820..692326) Helicobacter pylori J99 890290 NP_223341.1 CDS jhp0623 NC_000921.1 692366 692716 R similar to H. pylori 26695 gene HP0682; hypothetical protein complement(692366..692716) Helicobacter pylori J99 890288 NP_223342.1 CDS glmU NC_000921.1 692908 694209 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(692908..694209) Helicobacter pylori J99 890287 NP_223343.1 CDS fliP NC_000921.1 694306 695052 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 694306..695052 Helicobacter pylori J99 890284 NP_223344.1 CDS fecA_1 NC_000921.1 695096 697399 R similar to H. pylori 26695 gene HP0686; iron(III) dicitrate transport protein complement(695096..697399) Helicobacter pylori J99 890282 NP_223345.1 CDS feoB NC_000921.1 697655 699583 R similar to H. pylori 26695 gene HP0687; ferrous iron transport protein B complement(697655..699583) Helicobacter pylori J99 890280 NP_223346.1 CDS jhp0628 NC_000921.1 699704 700534 D similar to H. pylori 26695 gene HP0688 and HP0689; hypothetical protein 699704..700534 Helicobacter pylori J99 890277 NP_223347.1 CDS jhp0629 NC_000921.1 700587 701801 D type II DNA modification enzyme 700587..701801 Helicobacter pylori J99 890281 NP_223348.1 CDS jhp0630 NC_000921.1 701804 702676 D type II restriction enzyme 701804..702676 Helicobacter pylori J99 890279 NP_223349.1 CDS jhp0631 NC_000921.1 702854 703354 R similar to H. pylori 26695 gene HP0697; hypothetical protein complement(702854..703354) Helicobacter pylori J99 890278 NP_223350.1 CDS jhp0632 NC_000921.1 703378 705675 R similar to H. pylori 26695 gene HP0696; N-methylhydantoinase complement(703378..705675) Helicobacter pylori J99 890267 NP_223351.1 CDS jhp0633 NC_000921.1 705687 707825 R similar to H. pylori 26695 gene HP0695; hydantoin utilization complement(705687..707825) Helicobacter pylori J99 890276 NP_223352.1 CDS jhp0634 NC_000921.1 708056 709066 R similar to H. pylori 26695 gene HP0694; hypothetical protein complement(708056..709066) Helicobacter pylori J99 890275 NP_223353.1 CDS atoE NC_000921.1 709195 710559 R similar to H. pylori 26695 gene HP0693; short-chain fatty acids transporter complement(709195..710559) Helicobacter pylori J99 890273 NP_223354.1 CDS scoB NC_000921.1 710579 711202 R similar to H. pylori 26695 gene HP0692; 3-oxoacid CoA-transferase subunit B complement(710579..711202) Helicobacter pylori J99 890274 NP_223355.1 CDS scoA NC_000921.1 711199 711897 R similar to H. pylori 26695 gene HP0691; 3-oxoacid CoA-transferase subunit A complement(711199..711897) Helicobacter pylori J99 890270 NP_223356.1 CDS thl NC_000921.1 711908 713083 R similar to H. pylori 26695 gene HP0690; acetyl-COA acetyltransferase complement(711908..713083) Helicobacter pylori J99 890271 NP_223357.1 CDS jhp0639 NC_000921.1 713348 714376 D similar to H. pylori 26695 gene HP0699; hypothetical protein 713348..714376 Helicobacter pylori J99 890269 NP_223358.1 CDS dgkA NC_000921.1 714369 714755 D similar to H. pylori 26695 gene HP0700; diacylglycerol kinase 714369..714755 Helicobacter pylori J99 890264 NP_223359.1 CDS gyrA NC_000921.1 714771 717257 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 714771..717257 Helicobacter pylori J99 890268 NP_223360.1 CDS jhp0642 NC_000921.1 717257 717730 D similar to H. pylori 26695 gene HP0702; hypothetical protein 717257..717730 Helicobacter pylori J99 890266 NP_223361.1 CDS jhp0643 NC_000921.1 717727 718872 D similar to H. pylori 26695 gene HP0703; transcriptional regulator 717727..718872 Helicobacter pylori J99 890265 NP_223362.1 CDS uvrA NC_000921.1 719545 722370 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(719545..722370) Helicobacter pylori J99 890262 NP_223363.1 CDS hopE NC_000921.1 722544 723356 D similar to H. pylori 26695 gene HP0706; Outer membrane protein/porin 722544..723356 Helicobacter pylori J99 890263 NP_223364.1 CDS mraW NC_000921.1 723528 724454 D similar to H. pylori 26695 gene HP0707; S-adenosyl-methyltransferase MraW 723528..724454 Helicobacter pylori J99 890261 NP_223365.1 CDS jhp0647 NC_000921.1 724475 724819 D similar to H. pylori 26695 gene HP0708; hypothetical protein 724475..724819 Helicobacter pylori J99 890260 NP_223366.1 CDS jhp0648 NC_000921.1 725292 726194 D similar to H. pylori 26695 gene HP0709; hypothetical protein 725292..726194 Helicobacter pylori J99 890256 NP_223367.1 CDS jhp0649 NC_000921.1 726428 728401 D similar to H. pylori 26695 gene HP0710; hypothetical protein 726428..728401 Helicobacter pylori J99 890259 NP_223368.1 CDS jhp0650 NC_000921.1 728591 729811 D similar to H. pylori 26695 gene HP0711; hypothetical protein 728591..729811 Helicobacter pylori J99 890257 NP_223369.1 CDS jhp0651 NC_000921.1 729811 730515 D similar to H. pylori 26695 gene HP0712 and HP0713; hypothetical protein 729811..730515 Helicobacter pylori J99 890255 NP_223370.1 CDS rpoN NC_000921.1 730527 731771 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 complement(730527..731771) Helicobacter pylori J99 890249 NP_223371.1 CDS jhp0653 NC_000921.1 731774 732496 R similar to H. pylori 26695 gene HP0715; ABC transporter ATP-binding protein complement(731774..732496) Helicobacter pylori J99 890253 NP_223372.1 CDS jhp0654 NC_000921.1 732509 732910 R similar to H. pylori 26695 gene HP0716; hypothetical protein complement(732509..732910) Helicobacter pylori J99 890252 NP_223373.1 CDS dnaX NC_000921.1 732907 734655 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau complement(732907..734655) Helicobacter pylori J99 890248 NP_223374.1 CDS jhp0656 NC_000921.1 734722 735354 R similar to H. pylori 26695 gene HP0718; hypothetical protein complement(734722..735354) Helicobacter pylori J99 890247 NP_223375.1 CDS jhp0657 NC_000921.1 735622 736044 D similar to H. pylori 26695 gene HP0719 and HP0720; hypothetical protein 735622..736044 Helicobacter pylori J99 890246 NP_223376.1 CDS jhp0658 NC_000921.1 736072 736530 D similar to H. pylori 26695 gene HP0721; hypothetical protein 736072..736530 Helicobacter pylori J99 890245 NP_223377.1 CDS jhp0659 NC_000921.1 736846 738760 D similar to TIGR HP0722; expression of this protein is predicted to be regulated by slipped-strand repair at the (CT) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein join(736846..736882,736881..738760) Helicobacter pylori J99 890244 NP_223378.1 CDS dcuA NC_000921.1 738830 740161 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(738830..740161) Helicobacter pylori J99 890241 NP_223379.1 CDS ansB NC_000921.1 740291 741289 D similar to H. pylori 26695 gene HP0723; L-asparaginase II 740291..741289 Helicobacter pylori J99 890242 NP_223380.1 CDS jhp0662 NC_000921.1 741428 743381 R similar to TIGR HP0725; expression of this protein is predicted to be regulated by slipped-strand repair at the (CT) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein complement(join(741428..743346,743345..743381)) Helicobacter pylori J99 890243 NP_223381.1 CDS jhp0663 NC_000921.1 743602 744519 R similar to H. pylori 26695 gene HP0726; hypothetical protein complement(743602..744519) Helicobacter pylori J99 890240 NP_223382.1 CDS jhp0664 NC_000921.1 744489 745475 R similar to H. pylori 26695 gene HP0727; transcriptional regulator complement(744489..745475) Helicobacter pylori J99 890235 NP_223383.1 CDS jhp0665 NC_000921.1 745569 746585 R similar to H. pylori 26695 gene HP0728; hypothetical protein complement(745569..746585) Helicobacter pylori J99 890236 NP_223384.1 CDS jhp0666 NC_000921.1 746621 747688 R similar to H. pylori 26695 gene HP0729; hypothetical protein complement(746621..747688) Helicobacter pylori J99 890239 NP_223385.1 CDS jhp0667 NC_000921.1 747697 748002 R similar to H. pylori 26695 gene HP0730; hypothetical protein complement(747697..748002) Helicobacter pylori J99 890237 NP_223386.1 CDS jhp0668 NC_000921.1 748118 749827 R similar to H. pylori 26695 gene HP0731; hypothetical protein complement(748118..749827) Helicobacter pylori J99 890232 NP_223387.1 CDS jhp0669 NC_000921.1 749817 750932 R similar to H. pylori 26695 gene HP0732; hypothetical protein complement(749817..750932) Helicobacter pylori J99 890233 NP_223388.1 CDS jhp0670 NC_000921.1 750989 751567 R similar to H. pylori 26695 gene HP0733; hypothetical protein complement(750989..751567) Helicobacter pylori J99 890228 NP_223389.1 CDS jhp0671 NC_000921.1 751670 752989 R similar to H. pylori 26695 gene HP0734; hypothetical protein complement(751670..752989) Helicobacter pylori J99 890222 NP_223390.1 CDS gpt NC_000921.1 752991 753452 R similar to H. pylori 26695 gene HP0735; xanthine-guanine phosphoribosyltransferase complement(752991..753452) Helicobacter pylori J99 890227 NP_223391.1 CDS jhp0673 NC_000921.1 753461 754570 R similar to H. pylori 26695 gene HP0736; aminotransferase complement(753461..754570) Helicobacter pylori J99 890226 NP_223392.1 CDS pgpA NC_000921.1 754717 755193 D similar to H. pylori 26695 gene HP0737; phosphatidylglycerophosphatase A 754717..755193 Helicobacter pylori J99 890225 NP_223393.1 CDS ddl NC_000921.1 755270 756313 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 755270..756313 Helicobacter pylori J99 890224 NP_223394.1 CDS jhp0676 NC_000921.1 756314 757039 D similar to H. pylori 26695 gene HP0739; 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase 756314..757039 Helicobacter pylori J99 890223 NP_223395.1 CDS murF NC_000921.1 757026 758507 D similar to H. pylori 26695 gene HP0740; D-alanyl-D-alanine-adding enzyme 757026..758507 Helicobacter pylori J99 890221 NP_223396.1 CDS jhp0678 NC_000921.1 758517 759002 D similar to H. pylori 26695 gene HP0741; HIT family protein 758517..759002 Helicobacter pylori J99 890220 NP_223397.1 CDS prsA NC_000921.1 759067 760023 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 759067..760023 Helicobacter pylori J99 890219 NP_223398.1 CDS rodA_1 NC_000921.1 760074 761219 R similar to H. pylori 26695 gene HP0743; rod shape-determining protein complement(760074..761219) Helicobacter pylori J99 890218 NP_223399.1 CDS jhp0681 NC_000921.1 761242 762454 R similar to TIGR HP0744; expression of this protein is predicted to be regulated by slipped-strand repair at the (AG) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein complement(join(761242..762008,762007..762454)) Helicobacter pylori J99 890217 NP_223400.1 CDS jhp0682 NC_000921.1 762588 763571 D similar to H. pylori 26695 gene HP0745; hypothetical protein 762588..763571 Helicobacter pylori J99 890213 NP_223401.1 CDS jhp0683 NC_000921.1 763522 764781 D similar to H. pylori 26695 gene HP0746; hypothetical protein 763522..764781 Helicobacter pylori J99 890216 NP_223402.1 CDS trmB NC_000921.1 764792 765994 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 764792..765994 Helicobacter pylori J99 890215 NP_223403.1 CDS jhp0685 NC_000921.1 765969 766640 D similar to H. pylori 26695 gene HP0748; ABC transporter ATP-binding protein 765969..766640 Helicobacter pylori J99 890214 NP_223404.1 CDS jhp0686 NC_000921.1 766627 767433 D similar to H. pylori 26695 gene HP0749; hypothetical protein 766627..767433 Helicobacter pylori J99 890211 NP_223405.1 CDS jhp0687 NC_000921.1 767426 768628 D similar to H. pylori 26695 gene HP0750; hypothetical protein 767426..768628 Helicobacter pylori J99 890204 NP_223406.1 CDS jhp0688 NC_000921.1 768725 769084 D possibly involved in flagella export; flagellar protein FlaG 768725..769084 Helicobacter pylori J99 890212 NP_223407.1 CDS fliD NC_000921.1 769101 771158 D involved in flagellin assembly; flagellar capping protein 769101..771158 Helicobacter pylori J99 890207 NP_223408.1 CDS fliS NC_000921.1 771200 771580 D flagellin specific chaperone; flagellar protein FliS 771200..771580 Helicobacter pylori J99 890210 NP_223409.1 CDS jhp0691 NC_000921.1 771567 771806 D similar to H. pylori 26695 gene HP0754; hypothetical protein 771567..771806 Helicobacter pylori J99 890209 NP_223410.1 CDS jhp0692 NC_000921.1 771859 772566 D similar to H. pylori 26695 gene HP0755; hypothetical protein 771859..772566 Helicobacter pylori J99 890205 NP_223411.1 CDS jhp0693 NC_000921.1 772532 772678 D similar to H. pylori 26695 gene HP0756; hypothetical protein 772532..772678 Helicobacter pylori J99 890197 NP_223412.1 CDS jhp0694 NC_000921.1 772682 773560 D similar to H. pylori 26695 gene HP0757; hypothetical protein 772682..773560 Helicobacter pylori J99 890208 NP_223413.1 CDS jhp0695 NC_000921.1 773687 775000 D similar to H. pylori 26695 gene HP0758; hypothetical protein 773687..775000 Helicobacter pylori J99 890206 NP_223414.1 CDS jhp0696 NC_000921.1 775063 776316 D similar to H. pylori 26695 gene HP0759; hypothetical protein 775063..776316 Helicobacter pylori J99 890196 NP_223415.1 CDS jhp0697 NC_000921.1 776317 777906 R protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase complement(776317..777906) Helicobacter pylori J99 890203 NP_223416.1 CDS jhp0698 NC_000921.1 777806 778408 R similar to H. pylori 26695 gene HP0761; hypothetical protein complement(777806..778408) Helicobacter pylori J99 890202 NP_223417.1 CDS jhp0699 NC_000921.1 778572 779129 D similar to H. pylori 26695 gene HP0762; hypothetical protein 778572..779129 Helicobacter pylori J99 890200 NP_223418.1 CDS ftsY NC_000921.1 779135 780016 D similar to H. pylori 26695 gene HP0763; hypothetical protein 779135..780016 Helicobacter pylori J99 890201 NP_223419.1 CDS jhp0701 NC_000921.1 780303 780656 R similar to H. pylori 26695 gene HP0764; hypothetical protein complement(780303..780656) Helicobacter pylori J99 890199 NP_223420.1 CDS jhp0702 NC_000921.1 780684 781190 R similar to H. pylori 26695 gene HP0764; hypothetical protein complement(780684..781190) Helicobacter pylori J99 890198 NP_223421.1 CDS jhp0703 NC_000921.1 781141 782001 R similar to H. pylori 26695 gene HP0765; hypothetical protein complement(781141..782001) Helicobacter pylori J99 890194 NP_223422.1 CDS jhp0704 NC_000921.1 782013 782561 R similar to H. pylori 26695 gene HP0766; hypothetical protein complement(782013..782561) Helicobacter pylori J99 890195 NP_223423.1 CDS moaA NC_000921.1 782926 783891 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(782926..783891) Helicobacter pylori J99 890191 NP_223424.1 CDS mobA NC_000921.1 783977 784606 D MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 783977..784606 Helicobacter pylori J99 890193 NP_223425.1 CDS flhB NC_000921.1 784575 785651 D membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 784575..785651 Helicobacter pylori J99 890192 NP_223426.1 CDS jhp0708 NC_000921.1 785746 786483 R similar to H. pylori 26695 gene HP0771; hypothetical protein complement(785746..786483) Helicobacter pylori J99 890186 NP_223427.1 CDS amiA NC_000921.1 786502 787911 R similar to H. pylori 26695 gene HP0772; N-acetylmuramoyl-L-alanine amidase complement(786502..787911) Helicobacter pylori J99 890188 NP_223428.1 CDS jhp0710 NC_000921.1 787918 789009 R similar to H. pylori 26695 gene HP0773; hypothetical protein complement(787918..789009) Helicobacter pylori J99 890189 NP_223429.1 CDS tyrS NC_000921.1 789026 790234 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(789026..790234) Helicobacter pylori J99 890190 NP_223430.1 CDS spoT NC_000921.1 790254 792584 R similar to H. pylori 26695 gene HP0775; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase complement(790254..792584) Helicobacter pylori J99 890187 NP_223431.1 CDS jhp0713 NC_000921.1 792571 792795 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(792571..792795) Helicobacter pylori J99 890185 NP_223432.1 CDS pyrH NC_000921.1 792837 793559 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(792837..793559) Helicobacter pylori J99 890181 NP_223433.1 CDS jhp0715 NC_000921.1 793650 794333 R similar to H. pylori 26695 gene HP0778; hypothetical protein complement(793650..794333) Helicobacter pylori J99 890184 NP_223434.1 CDS acnB NC_000921.1 794464 797022 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 794464..797022 Helicobacter pylori J99 890183 NP_223435.1 CDS jhp0717 NC_000921.1 797103 797369 D similar to H. pylori 26695 gene HP0780; hypothetical protein 797103..797369 Helicobacter pylori J99 890182 NP_223436.1 CDS jhp0718 NC_000921.1 797664 798953 D similar to H. pylori 26695 gene HP0781; hypothetical protein 797664..798953 Helicobacter pylori J99 890180 NP_223437.1 CDS jhp0719 NC_000921.1 799047 800414 D similar to H. pylori 26695 gene HP0782; hypothetical protein 799047..800414 Helicobacter pylori J99 890177 NP_223438.1 CDS jhp0720 NC_000921.1 800421 800948 R similar to H. pylori 26695 gene HP0783; hypothetical protein complement(800421..800948) Helicobacter pylori J99 890178 NP_223439.1 CDS jhp0721 NC_000921.1 801287 801418 D similar to H. pylori 26695 gene HP0784; hypothetical protein 801287..801418 Helicobacter pylori J99 890179 NP_223440.1 CDS lolA NC_000921.1 801433 801987 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(801433..801987) Helicobacter pylori J99 890175 NP_223441.1 CDS secA NC_000921.1 802134 804731 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 802134..804731 Helicobacter pylori J99 890173 NP_223442.1 CDS jhp0724 NC_000921.1 804721 805953 D similar to H. pylori 26695 gene HP0787; hypothetical protein 804721..805953 Helicobacter pylori J99 890176 NP_223443.1 CDS jhp0725 NC_000921.1 806232 807731 D similar to H. pylori 26695 gene HP0788; hypothetical protein 806232..807731 Helicobacter pylori J99 890171 NP_223444.1 CDS hsdS_4 NC_000921.1 807943 809307 R type I restriction enzyme (specificity subunit) complement(807943..809307) Helicobacter pylori J99 890160 NP_223445.1 CDS hmcT NC_000921.1 809351 811411 R similar to H. pylori 26695 gene HP0791; heavy-metal cation-transporting P-type ATPase complement(809351..811411) Helicobacter pylori J99 890170 NP_223446.1 CDS jhp0728 NC_000921.1 811436 812956 R similar to H. pylori 26695 gene HP0792; hypothetical protein complement(811436..812956) Helicobacter pylori J99 890172 NP_223447.1 CDS def NC_000921.1 812962 813486 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(812962..813486) Helicobacter pylori J99 890168 NP_223448.1 CDS clpP NC_000921.1 813491 814078 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(813491..814078) Helicobacter pylori J99 890167 NP_223449.1 CDS tig NC_000921.1 814099 815454 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(814099..815454) Helicobacter pylori J99 890166 NP_223450.1 CDS jhp0732 NC_000921.1 815567 816403 R similar to H. pylori 26695 gene HP0796; hypothetical protein complement(815567..816403) Helicobacter pylori J99 890165 NP_223451.1 CDS hpaA NC_000921.1 816425 817207 R similar to H. pylori 26695 gene HP0797; neuraminyllactose-binding hemagglutinin precursor complement(816425..817207) Helicobacter pylori J99 890164 NP_223452.1 CDS moaC NC_000921.1 817326 817802 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(817326..817802) Helicobacter pylori J99 890163 NP_223453.1 CDS mogA NC_000921.1 817811 818341 R forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA complement(817811..818341) Helicobacter pylori J99 890162 NP_223454.1 CDS moaE NC_000921.1 818354 818791 R similar to H. pylori 26695 gene HP0800; molybdopterin converting factor, subunit 2 complement(818354..818791) Helicobacter pylori J99 890161 NP_223455.1 CDS moaD NC_000921.1 818792 819013 R similar to H. pylori 26695 gene HP0801; molybdopterin converting factor, subunit 1 complement(818792..819013) Helicobacter pylori J99 890157 NP_223456.1 CDS ribA NC_000921.1 819062 819640 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(819062..819640) Helicobacter pylori J99 890159 NP_223457.1 CDS jhp0739 NC_000921.1 819730 820569 R similar to H. pylori 26695 gene HP0803; hypothetical protein complement(819730..820569) Helicobacter pylori J99 890158 NP_223458.1 CDS ribBA NC_000921.1 820656 821690 R bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein complement(820656..821690) Helicobacter pylori J99 890155 NP_223459.1 CDS jhp0741 NC_000921.1 821788 822666 R similar to H. pylori 26695 gene HP0805; lipopolysaccharide biosynthesis protein complement(821788..822666) Helicobacter pylori J99 890156 NP_223460.1 CDS jhp0742 NC_000921.1 822715 823335 D similar to H. pylori 26695 gene HP0806; hypothetical protein 822715..823335 Helicobacter pylori J99 890152 NP_223461.1 CDS fecA_2 NC_000921.1 823346 825724 R similar to H. pylori 26695 gene HP0807; iron(III) dicitrate transport protein complement(823346..825724) Helicobacter pylori J99 890153 NP_223462.1 CDS acpS NC_000921.1 825922 826281 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(825922..826281) Helicobacter pylori J99 890149 NP_223463.1 CDS fliL NC_000921.1 826288 826839 R interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL complement(826288..826839) Helicobacter pylori J99 890151 NP_223464.1 CDS jhp0746 NC_000921.1 826848 827450 R similar to H. pylori 26695 gene HP0810; hypothetical protein complement(826848..827450) Helicobacter pylori J99 890150 NP_223465.1 CDS jhp0747 NC_000921.1 827429 827755 R similar to H. pylori 26695 gene HP0811; hypothetical protein complement(827429..827755) Helicobacter pylori J99 890145 NP_223466.1 CDS jhp0748 NC_000921.1 828209 829219 R similar to H. pylori 26695 gene HP0812; hypothetical protein complement(828209..829219) Helicobacter pylori J99 890147 NP_223467.1 CDS jhp0749 NC_000921.1 829352 829969 D similar to H. pylori 26695 gene HP0813; hypothetical protein 829352..829969 Helicobacter pylori J99 890148 NP_223468.1 CDS moeB NC_000921.1 829970 830737 D similar to H. pylori 26695 gene HP0814; molybdopterin-synthase sulfurylase 829970..830737 Helicobacter pylori J99 890146 NP_223469.1 CDS motA NC_000921.1 830753 831526 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 830753..831526 Helicobacter pylori J99 890144 NP_223470.1 CDS motB NC_000921.1 831529 832302 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 831529..832302 Helicobacter pylori J99 890143 NP_223471.1 CDS jhp0753 NC_000921.1 832299 832745 D similar to H. pylori 26695 gene HP0817; hypothetical protein 832299..832745 Helicobacter pylori J99 890141 NP_223472.1 CDS jhp0754 NC_000921.1 832859 833344 D similar to H. pylori 26695 gene HP0818; osmoprotection binding protein 832859..833344 Helicobacter pylori J99 890142 NP_223473.1 CDS jhp0755 NC_000921.1 833221 833793 R hypothetical protein complement(833221..833793) Helicobacter pylori J99 890139 NP_223474.1 CDS jhp0756 NC_000921.1 833787 834605 R type II DNA modification enzyme complement(833787..834605) Helicobacter pylori J99 890137 NP_223475.1 CDS jhp0757 NC_000921.1 834901 836562 D similar to H. pylori 26695 gene HP0818; osmoprotection binding protein 834901..836562 Helicobacter pylori J99 890138 NP_223476.1 CDS jhp0758 NC_000921.1 836565 837215 D similar to H. pylori 26695 gene HP0819; osmoprotection ATP-binding protein 836565..837215 Helicobacter pylori J99 890130 NP_223477.1 CDS jhp0759 NC_000921.1 837390 837851 D similar to H. pylori 26695 gene HP0820; hypothetical protein 837390..837851 Helicobacter pylori J99 890136 NP_223478.1 CDS uvrC NC_000921.1 837852 839636 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 837852..839636 Helicobacter pylori J99 890135 NP_223479.1 CDS hom NC_000921.1 839646 840911 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 839646..840911 Helicobacter pylori J99 890134 NP_223480.1 CDS jhp0762 NC_000921.1 840912 841256 D similar to H. pylori 26695 gene HP0823; hypothetical protein 840912..841256 Helicobacter pylori J99 890133 NP_223481.1 CDS trxA NC_000921.1 841348 841668 D similar to H. pylori 26695 gene HP0824; thioredoxin 841348..841668 Helicobacter pylori J99 890132 NP_223482.1 CDS trxB_1 NC_000921.1 841674 842609 D similar to H. pylori 26695 gene HP0825; thioredoxin reductase 841674..842609 Helicobacter pylori J99 890127 NP_223483.1 CDS jhp0765 NC_000921.1 842976 843797 D similar to H. pylori 26695 gene HP0826; lipopolysaccharide biosynthesis protein 842976..843797 Helicobacter pylori J99 890131 NP_223484.1 CDS jhp0766 NC_000921.1 844007 844255 R similar to H. pylori 26695 gene HP0827; hypothetical protein complement(844007..844255) Helicobacter pylori J99 890129 NP_223485.1 CDS atpB NC_000921.1 844583 845263 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(844583..845263) Helicobacter pylori J99 890120 NP_223486.1 CDS guaB NC_000921.1 845385 846830 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(845385..846830) Helicobacter pylori J99 890128 NP_223487.1 CDS gatA NC_000921.1 846840 848201 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(846840..848201) Helicobacter pylori J99 890125 NP_223488.1 CDS coaE NC_000921.1 848260 848850 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(848260..848850) Helicobacter pylori J99 890126 NP_223489.1 CDS speE NC_000921.1 848852 849640 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(848852..849640) Helicobacter pylori J99 890122 NP_223490.1 CDS jhp0772 NC_000921.1 849733 850623 R similar to H. pylori 26695 gene HP0833; hypothetical protein complement(849733..850623) Helicobacter pylori J99 890123 NP_223491.1 CDS engA NC_000921.1 850700 852088 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 850700..852088 Helicobacter pylori J99 890124 NP_223492.1 CDS jhp0774 NC_000921.1 852229 852513 D similar to H. pylori 26695 gene HP0835; DNA-binding protein HU 852229..852513 Helicobacter pylori J99 890121 NP_223493.1 CDS jhp0775 NC_000921.1 853193 853798 D similar to H. pylori 26695 gene HP0836 and HP0837; hypothetical protein 853193..853798 Helicobacter pylori J99 890118 NP_223494.1 CDS jhp0776 NC_000921.1 853818 854435 D similar to H. pylori 26695 gene HP0838; hypothetical protein 853818..854435 Helicobacter pylori J99 890119 NP_223495.1 CDS jhp0777 NC_000921.1 854432 856195 D similar to H. pylori 26695 gene HP0839; hypothetical protein 854432..856195 Helicobacter pylori J99 890115 NP_223496.1 CDS jhp0778 NC_000921.1 856199 857200 D similar to H. pylori 26695 gene HP0840; sugar nucleotide biosynthesis protein 856199..857200 Helicobacter pylori J99 890117 NP_223497.1 CDS dfp NC_000921.1 857197 858474 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 857197..858474 Helicobacter pylori J99 890112 NP_223498.1 CDS jhp0780 NC_000921.1 858474 859211 D similar to H. pylori 26695 gene HP0842; hypothetical protein 858474..859211 Helicobacter pylori J99 890116 NP_223499.1 CDS thiE NC_000921.1 859321 859974 R Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase complement(859321..859974) Helicobacter pylori J99 890113 NP_223500.1 CDS thiD NC_000921.1 859967 860776 R similar to H. pylori 26695 gene HP0844; phosphomethylpyrimidine kinase complement(859967..860776) Helicobacter pylori J99 890106 NP_223501.1 CDS thiM NC_000921.1 860773 861552 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(860773..861552) Helicobacter pylori J99 890114 NP_223502.1 CDS hsdR_2 NC_000921.1 861645 864272 R similar to H. pylori 26695 gene HP0846; type I restriction enzyme restriction subunit complement(861645..864272) Helicobacter pylori J99 890111 NP_223503.1 CDS hsdS_2 NC_000921.1 864828 865451 R similar to H. pylori 26695 gene HP0848 and HP0849; type I restrictionenzyme (specificity subunit) complement(864828..865451) Helicobacter pylori J99 890110 NP_223504.1 CDS hsdM_2 NC_000921.1 865462 867048 R similar to H. pylori 26695 gene HP0850; type I restriction enzyme modification subunit complement(865462..867048) Helicobacter pylori J99 890109 NP_223505.1 CDS jhp0787 NC_000921.1 867227 867913 D similar to H. pylori 26695 gene HP0851; hypothetical protein 867227..867913 Helicobacter pylori J99 890108 NP_223506.1 CDS jhp0788 NC_000921.1 867956 868897 R similar to H. pylori 26695 gene HP0852; hypothetical protein complement(867956..868897) Helicobacter pylori J99 890107 NP_223507.1 CDS jhp0789 NC_000921.1 868894 870495 R similar to H. pylori 26695 gene HP0853; ABC transporter ATP-binding protein complement(868894..870495) Helicobacter pylori J99 890103 NP_223508.1 CDS guaC NC_000921.1 870697 871674 D similar to H. pylori 26695 gene HP0854; guanosine 5'-monophosphate oxidoreductase 870697..871674 Helicobacter pylori J99 890104 NP_223509.1 CDS gmhA NC_000921.1 871698 872276 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(871698..872276) Helicobacter pylori J99 890105 NP_223510.1 CDS waaE NC_000921.1 872269 873660 R similar to H. pylori 26695 gene HP0858; ADP-D-glycero-D-mannoheptose synthase complement(872269..873660) Helicobacter pylori J99 890101 NP_223511.1 CDS gmhD NC_000921.1 873657 874646 R similar to H. pylori 26695 gene HP0859; ADP-L-glycero-D-manno-heptose-6-epimerase complement(873657..874646) Helicobacter pylori J99 890102 NP_223512.1 CDS jhp0794 NC_000921.1 874656 875180 R similar to H. pylori 26695 gene HP0860; hypothetical protein complement(874656..875180) Helicobacter pylori J99 890098 NP_223513.1 CDS jhp0795 NC_000921.1 875167 875904 R similar to H. pylori 26695 gene HP0861; hypothetical protein complement(875167..875904) Helicobacter pylori J99 890100 NP_223514.1 CDS jhp0796 NC_000921.1 875895 876566 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(875895..876566) Helicobacter pylori J99 890099 NP_223515.1 CDS jhp0797 NC_000921.1 876571 878196 R similar to H. pylori 26695 gene HP0863; hypothetical protein complement(876571..878196) Helicobacter pylori J99 890094 NP_223516.1 CDS jhp0798 NC_000921.1 878201 878857 R similar to H. pylori 26695 gene HP0864; hypothetical protein complement(878201..878857) Helicobacter pylori J99 890092 NP_223517.1 CDS dut NC_000921.1 878854 879291 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(878854..879291) Helicobacter pylori J99 890097 NP_223518.1 CDS greA NC_000921.1 879281 879775 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(879281..879775) Helicobacter pylori J99 890096 NP_223519.1 CDS lpxB NC_000921.1 879816 880898 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase complement(879816..880898) Helicobacter pylori J99 890095 NP_223520.1 CDS jhp0802 NC_000921.1 880898 881359 R similar to H. pylori 26695 gene HP0868; hypothetical protein complement(880898..881359) Helicobacter pylori J99 890090 NP_223521.1 CDS hypA NC_000921.1 881366 881719 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein complement(881366..881719) Helicobacter pylori J99 890093 NP_223522.1 CDS flgE NC_000921.1 881778 883934 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(881778..883934) Helicobacter pylori J99 890091 NP_223523.1 CDS cdh NC_000921.1 884143 884877 R similar to H. pylori 26695 gene HP0871; CDP-diacylglycerol pyrophosphatase complement(884143..884877) Helicobacter pylori J99 890088 NP_223524.1 CDS phnA NC_000921.1 885154 885483 D similar to H. pylori 26695 gene HP0872; alkylphosphonate uptake protein 885154..885483 Helicobacter pylori J99 890089 NP_223525.1 CDS jhp0807 NC_000921.1 885541 885756 R similar to H. pylori 26695 gene HP0873; hypothetical protein complement(885541..885756) Helicobacter pylori J99 890081 NP_223526.1 CDS jhp0808 NC_000921.1 885841 886719 R similar to H. pylori 26695 gene HP0874; hypothetical protein complement(885841..886719) Helicobacter pylori J99 890087 NP_223527.1 CDS katA NC_000921.1 886867 888384 R similar to H. pylori 26695 gene HP0875; catalase complement(886867..888384) Helicobacter pylori J99 890086 NP_223528.1 CDS frpB_1 NC_000921.1 888708 891083 D similar to H. pylori 26695 gene HP0876; IRON-regulated outer membrane protein 888708..891083 Helicobacter pylori J99 890085 NP_223529.1 CDS ruvC NC_000921.1 891084 891557 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(891084..891557) Helicobacter pylori J99 890084 NP_223530.1 CDS jhp0812 NC_000921.1 891689 892420 D similar to H. pylori 26695 gene HP0878 and HP0879; hypothetical protein 891689..892420 Helicobacter pylori J99 890083 NP_223531.1 CDS jhp0813 NC_000921.1 893499 893966 R hypothetical protein complement(893499..893966) Helicobacter pylori J99 890082 NP_223532.1 CDS jhp0814 NC_000921.1 893875 894228 R hypothetical protein complement(893875..894228) Helicobacter pylori J99 890079 NP_223533.1 CDS ruvA NC_000921.1 894351 894902 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(894351..894902) Helicobacter pylori J99 890076 NP_223534.1 CDS jhp0816 NC_000921.1 894929 896773 R similar to H. pylori 26695 gene HP0884; hypothetical protein complement(894929..896773) Helicobacter pylori J99 890078 NP_223535.1 CDS jhp0817 NC_000921.1 896944 898326 D similar to H. pylori 26695 gene HP0885; hypothetical protein 896944..898326 Helicobacter pylori J99 890074 NP_223536.1 CDS cysS NC_000921.1 898327 899724 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 898327..899724 Helicobacter pylori J99 890077 NP_223537.1 CDS vacA NC_000921.1 900011 903877 D similar to H. pylori 26695 gene HP0887; vacuolating cytotoxin 900011..903877 Helicobacter pylori J99 890075 NP_223538.1 CDS jhp0820 NC_000921.1 903994 905115 R lipopolysaccharide biosynthesis protein complement(903994..905115) Helicobacter pylori J99 890073 NP_223539.1 CDS fecE NC_000921.1 905179 905946 R similar to H. pylori 26695 gene HP0888; IRON(III) dicitrate transport system ATP-binding protein complement(905179..905946) Helicobacter pylori J99 890072 NP_223540.1 CDS fecD NC_000921.1 905946 906926 R similar to H. pylori 26695 gene HP0889; iron ABC transporter permease complement(905946..906926) Helicobacter pylori J99 890065 NP_223541.1 CDS jhp0823 NC_000921.1 906919 907734 R similar to H. pylori 26695 gene HP0890; hypothetical protein complement(906919..907734) Helicobacter pylori J99 890071 NP_223542.1 CDS jhp0824 NC_000921.1 907916 908440 D similar to H. pylori 26695 gene HP0891; hypothetical protein 907916..908440 Helicobacter pylori J99 890070 NP_223543.1 CDS jhp0825 NC_000921.1 908515 908817 R hypothetical protein complement(908515..908817) Helicobacter pylori J99 890066 NP_223544.1 CDS tnpB NC_000921.1 908966 910294 R IS606 transposase complement(908966..910294) Helicobacter pylori J99 890069 NP_223545.1 CDS tnpA NC_000921.1 910322 910516 D IS606 transposase 910322..910516 Helicobacter pylori J99 890063 NP_223546.1 CDS jhp0828 NC_000921.1 910638 910844 R hypothetical protein complement(910638..910844) Helicobacter pylori J99 890064 NP_223547.1 CDS jhp0829 NC_000921.1 910912 911058 R hypothetical protein complement(910912..911058) Helicobacter pylori J99 890059 NP_223548.1 CDS jhp0830 NC_000921.1 911422 911673 R hypothetical protein complement(911422..911673) Helicobacter pylori J99 890061 NP_223549.1 CDS jhp0831 NC_000921.1 911721 911993 R similar to H. pylori 26695 gene HP0892; hypothetical protein complement(911721..911993) Helicobacter pylori J99 890062 NP_223550.1 CDS jhp0832 NC_000921.1 912007 912294 R similar to H. pylori 26695 gene HP0893; hypothetical protein complement(912007..912294) Helicobacter pylori J99 890060 NP_223551.1 CDS babA NC_000921.1 912790 915024 R similar to H. pylori 26695 gene HP1243; hypothetical protein complement(912790..915024) Helicobacter pylori J99 890058 NP_223552.1 CDS jhp0834 NC_000921.1 916021 916431 R hypothetical protein complement(916021..916431) Helicobacter pylori J99 890056 NP_223553.1 CDS hypD NC_000921.1 916398 917510 R similar to H. pylori 26695 gene HP0898; hydrogenase expression/formation protein complement(916398..917510) Helicobacter pylori J99 890057 NP_223554.1 CDS hypC NC_000921.1 917525 917761 R similar to H. pylori 26695 gene HP0899; hydrogenase expression/formation protein complement(917525..917761) Helicobacter pylori J99 890052 NP_223555.1 CDS hypB NC_000921.1 917761 918489 R similar to H. pylori 26695 gene HP0900; hydrogenase expression/formation protein complement(917761..918489) Helicobacter pylori J99 890055 NP_223556.1 CDS jhp0838 NC_000921.1 918602 918730 R similar to H. pylori 26695 gene HP0901; hypothetical protein complement(918602..918730) Helicobacter pylori J99 890053 NP_223557.1 CDS jhp0839 NC_000921.1 918741 919040 R similar to H. pylori 26695 gene HP0902; hypothetical protein complement(918741..919040) Helicobacter pylori J99 890054 NP_223558.1 CDS ackA NC_000921.1 919040 920251 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(919040..920251) Helicobacter pylori J99 890045 NP_223559.1 CDS pta NC_000921.1 920263 921822 R similar to H. pylori 26695 gene HP0904 and HP0905; phosphotransacetylase complement(920263..921822) Helicobacter pylori J99 890051 NP_223560.1 CDS jhp0842 NC_000921.1 922003 923577 D similar to H. pylori 26695 gene HP0906; hypothetical protein 922003..923577 Helicobacter pylori J99 890050 NP_223561.1 CDS flgD NC_000921.1 923628 924719 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 923628..924719 Helicobacter pylori J99 890049 NP_223562.1 CDS flgE NC_000921.1 924716 926533 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 924716..926533 Helicobacter pylori J99 890048 NP_223563.1 CDS jhp0845 NC_000921.1 926585 927166 D similar to H. pylori 26695 gene HP0909; hypothetical protein 926585..927166 Helicobacter pylori J99 890047 NP_223564.1 CDS jhp0846 NC_000921.1 927176 928321 D similar to H. pylori 26695 gene HP0910; type II DNA modification (methyltransferase 927176..928321 Helicobacter pylori J99 890040 NP_223565.1 CDS jhp0847 NC_000921.1 928330 930360 D similar to H. pylori 26695 gene HP0911; ATP-dependent helicase 928330..930360 Helicobacter pylori J99 890046 NP_223566.1 CDS hopC NC_000921.1 931524 933086 D similar to H. pylori 26695 gene HP0912; Outer membrane protein/porin 931524..933086 Helicobacter pylori J99 890044 NP_223567.1 CDS hopB NC_000921.1 933108 934691 D similar to H. pylori 26695 gene HP0913; Outer membrane protein/porin 933108..934691 Helicobacter pylori J99 890042 NP_223568.1 CDS jhp0850 NC_000921.1 935476 937020 R similar to H. pylori 26695 gene HP0914; hypothetical protein complement(935476..937020) Helicobacter pylori J99 890043 NP_223569.1 CDS frpB_2 NC_000921.1 937358 939805 R similar to H. pylori 26695 gene HP0915 and HP0916; IRON-regulated outer membrane protein complement(937358..939805) Helicobacter pylori J99 890041 NP_223570.1 CDS jhp0852 NC_000921.1 939981 940412 R similar to H. pylori 26695 gene HP0918; hypothetical protein complement(939981..940412) Helicobacter pylori J99 890037 NP_223571.1 CDS carB NC_000921.1 940417 943674 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(940417..943674) Helicobacter pylori J99 890029 NP_223572.1 CDS jhp0854 NC_000921.1 943774 944466 R similar to H. pylori 26695 gene HP0920; hypothetical protein complement(943774..944466) Helicobacter pylori J99 890039 NP_223573.1 CDS gap_1 NC_000921.1 944612 945610 D similar to H. pylori 26695 gene HP0921; glyceraldehyde 3-phosphate dehydrogenase 944612..945610 Helicobacter pylori J99 890038 NP_223574.1 CDS jhp0856 NC_000921.1 945691 952890 D similar to H. pylori 26695 gene HP0922; vacuolating cytotoxin (VacA) paralog 945691..952890 Helicobacter pylori J99 890036 NP_223575.1 CDS jhp0857 NC_000921.1 952943 954043 D similar to H. pylori 26695 gene HP0923; hypothetical protein 952943..954043 Helicobacter pylori J99 890035 NP_223576.1 CDS jhp0858 NC_000921.1 954113 954319 R similar to H. pylori 26695 gene HP0924; hypothetical protein complement(954113..954319) Helicobacter pylori J99 890034 NP_223577.1 CDS recR NC_000921.1 954488 955069 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 954488..955069 Helicobacter pylori J99 890033 NP_223578.1 CDS truD NC_000921.1 955066 956211 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 955066..956211 Helicobacter pylori J99 890027 NP_223579.1 CDS htpX NC_000921.1 956198 957130 D metalloprotease; heat shock protein HtpX 956198..957130 Helicobacter pylori J99 890025 NP_223580.1 CDS folE_1 NC_000921.1 957131 957343 D similar to H. pylori 26695 gene HP0928; GTP cyclohydrolase I 957131..957343 Helicobacter pylori J99 890032 NP_223581.1 CDS folE NC_000921.1 957598 958140 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 957598..958140 Helicobacter pylori J99 890024 NP_223582.1 CDS ispA NC_000921.1 958156 959067 D similar to H. pylori 26695 gene HP0929; geranyltranstransferase 958156..959067 Helicobacter pylori J99 890030 NP_223583.1 CDS surE NC_000921.1 959064 959867 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 959064..959867 Helicobacter pylori J99 890031 NP_223584.1 CDS jhp0866 NC_000921.1 959864 960523 D similar to H. pylori 26695 gene HP0931 and HP0932; hypothetical protein 959864..960523 Helicobacter pylori J99 890026 NP_223585.1 CDS jhp0867 NC_000921.1 960525 961127 D similar to H. pylori 26695 gene HP0933; hypothetical protein 960525..961127 Helicobacter pylori J99 890028 NP_223586.1 CDS jhp0868 NC_000921.1 961124 961879 D similar to H. pylori 26695 gene HP0934; hypothetical protein 961124..961879 Helicobacter pylori J99 889179 NP_223587.1 CDS jhp0869 NC_000921.1 961971 962456 D similar to H. pylori 26695 gene HP0935; hypothetical protein 961971..962456 Helicobacter pylori J99 890283 NP_223588.1 CDS jhp0870 NC_000921.1 962682 964688 D hypothetical protein 962682..964688 Helicobacter pylori J99 889515 NP_223589.1 CDS proP NC_000921.1 965126 966484 R similar to H. pylori 26695 gene HP0936; proline/betaine transporter complement(965126..966484) Helicobacter pylori J99 889519 NP_223590.1 CDS jhp0872 NC_000921.1 966767 967591 R similar to H. pylori 26695 gene HP0937; hypothetical protein complement(966767..967591) Helicobacter pylori J99 889514 NP_223591.1 CDS jhp0873 NC_000921.1 967598 968473 R similar to H. pylori 26695 gene HP0938; hypothetical protein complement(967598..968473) Helicobacter pylori J99 889516 NP_223592.1 CDS jhp0874 NC_000921.1 968545 969258 R similar to H. pylori 26695 gene HP0939; amino acid ABC transporter permease complement(968545..969258) Helicobacter pylori J99 889517 NP_223593.1 CDS jhp0875 NC_000921.1 969242 970015 R similar to H. pylori 26695 gene HP0940; amino acid ABC transporter complement(969242..970015) Helicobacter pylori J99 889531 NP_223594.1 CDS alr NC_000921.1 970081 971214 R similar to H. pylori 26695 gene HP0941; alanine racemase complement(970081..971214) Helicobacter pylori J99 889518 NP_223595.1 CDS jhp0877 NC_000921.1 971221 972573 R similar to H. pylori 26695 gene HP0942; sodium/alanine symporter complement(971221..972573) Helicobacter pylori J99 889520 NP_223596.1 CDS dadA NC_000921.1 972614 973846 R similar to H. pylori 26695 gene HP0943; D-amino acid dehydrogenase complement(972614..973846) Helicobacter pylori J99 889521 NP_223597.1 CDS jhp0879 NC_000921.1 973869 974246 R similar to H. pylori 26695 gene HP0944; hypothetical protein complement(973869..974246) Helicobacter pylori J99 889522 NP_223598.1 CDS jhp0880 NC_000921.1 975154 976635 D similar to H. pylori 26695 gene HP0946; hypothetical protein 975154..976635 Helicobacter pylori J99 889523 NP_223599.1 CDS jhp0881 NC_000921.1 976960 977322 D similar to H. pylori 26695 gene HP0947; hypothetical protein 976960..977322 Helicobacter pylori J99 889524 NP_223600.1 CDS jhp0882 NC_000921.1 977734 978747 R similar to H. pylori 26695 gene HP0948; hypothetical protein complement(977734..978747) Helicobacter pylori J99 889537 NP_223601.1 CDS jhp0883 NC_000921.1 978757 979209 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(978757..979209) Helicobacter pylori J99 889525 NP_223602.1 CDS accD NC_000921.1 979223 980092 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(979223..980092) Helicobacter pylori J99 889526 NP_223603.1 CDS jhp0885 NC_000921.1 980173 980787 D similar to H. pylori 26695 gene HP0951; recombination protein RecO 980173..980787 Helicobacter pylori J99 889527 NP_223604.1 CDS jhp0886 NC_000921.1 980798 981454 D similar to H. pylori 26695 gene HP0952; hypothetical protein 980798..981454 Helicobacter pylori J99 889528 NP_223605.1 CDS jhp0887 NC_000921.1 981457 982023 R similar to H. pylori 26695 gene HP0953; hypothetical protein complement(981457..982023) Helicobacter pylori J99 889529 NP_223606.1 CDS jhp0888 NC_000921.1 982088 982720 R similar to H. pylori 26695 gene HP0954; aldehyde dehydrogenase complement(982088..982720) Helicobacter pylori J99 889563 NP_223607.1 CDS lgt NC_000921.1 982720 983571 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(982720..983571) Helicobacter pylori J99 889530 NP_223608.1 CDS jhp0890 NC_000921.1 983580 984308 R similar to H. pylori 26695 gene HP0956; hypothetical protein complement(983580..984308) Helicobacter pylori J99 889532 NP_223609.1 CDS waaA NC_000921.1 984326 985507 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(984326..985507) Helicobacter pylori J99 889533 NP_223610.1 CDS jhp0892 NC_000921.1 985508 986311 R similar to H. pylori 26695 gene HP0958; hypothetical protein complement(985508..986311) Helicobacter pylori J99 889534 NP_223611.1 CDS jhp0893 NC_000921.1 986321 987052 R similar to H. pylori 26695 gene HP0959; hypothetical protein complement(986321..987052) Helicobacter pylori J99 889546 NP_223612.1 CDS glyQ NC_000921.1 987054 987950 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(987054..987950) Helicobacter pylori J99 889535 NP_223613.1 CDS gpsA NC_000921.1 987964 988902 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(987964..988902) Helicobacter pylori J99 889536 NP_223614.1 CDS jhp0896 NC_000921.1 989179 989871 R hypothetical protein complement(989179..989871) Helicobacter pylori J99 889538 NP_223615.1 CDS jhp0897 NC_000921.1 990227 990907 R similar to H. pylori 26695 gene HP0963; hypothetical protein complement(990227..990907) Helicobacter pylori J99 889539 NP_223616.1 CDS jhp0898 NC_000921.1 990904 991638 R similar to H. pylori 26695 gene HP0964; hypothetical protein complement(990904..991638) Helicobacter pylori J99 889540 NP_223617.1 CDS jhp0899 NC_000921.1 991704 993206 R similar to H. pylori 26695 gene HP0964 and HP0965; hypothetical protein complement(991704..993206) Helicobacter pylori J99 889541 NP_223618.1 CDS jhp0900 NC_000921.1 993206 994228 R similar to H. pylori 26695 gene HP0966; hypothetical protein complement(993206..994228) Helicobacter pylori J99 889542 NP_223619.1 CDS jhp0901 NC_000921.1 994288 994788 R similar to H. pylori 26695 gene HP0966; hypothetical protein complement(994288..994788) Helicobacter pylori J99 889543 NP_223620.1 CDS jhp0902 NC_000921.1 995162 995443 R similar to H. pylori 26695 gene HP0968; hypothetical protein complement(995162..995443) Helicobacter pylori J99 889544 NP_223621.1 CDS czcA_1 NC_000921.1 995459 998518 R similar to H. pylori 26695 gene HP0969; cation efflux system protein complement(995459..998518) Helicobacter pylori J99 889550 NP_223622.1 CDS czcB_1 NC_000921.1 998518 999597 R similar to H. pylori 26695 gene HP0970; cation efflux system protein complement(998518..999597) Helicobacter pylori J99 889545 NP_223623.1 CDS jhp0905 NC_000921.1 999594 1000889 R similar to H. pylori 26695 gene HP0971; hypothetical protein complement(999594..1000889) Helicobacter pylori J99 889547 NP_223624.1 CDS glyS NC_000921.1 1000879 1002984 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1000879..1002984) Helicobacter pylori J99 889549 NP_223625.1 CDS jhp0907 NC_000921.1 1003101 1004189 D similar to H. pylori 26695 gene HP0973; hypothetical protein 1003101..1004189 Helicobacter pylori J99 889554 NP_223626.1 CDS pgm NC_000921.1 1004202 1005677 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1004202..1005677 Helicobacter pylori J99 889548 NP_223627.1 CDS gatC NC_000921.1 1005692 1005973 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1005692..1005973 Helicobacter pylori J99 889551 NP_223628.1 CDS bioA NC_000921.1 1006070 1007389 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(1006070..1007389) Helicobacter pylori J99 889552 NP_223629.1 CDS jhp0911 NC_000921.1 1007519 1008982 D similar to H. pylori 26695 gene HP0977; hypothetical protein 1007519..1008982 Helicobacter pylori J99 889571 NP_223630.1 CDS ftsA NC_000921.1 1008998 1010479 D similar to H. pylori 26695 gene HP0978; septum formation protein 1008998..1010479 Helicobacter pylori J99 889553 NP_223631.1 CDS ftsZ NC_000921.1 1010607 1011764 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1010607..1011764 Helicobacter pylori J99 889557 NP_223632.1 CDS jhp0914 NC_000921.1 1012090 1013325 R hypothetical protein complement(1012090..1013325) Helicobacter pylori J99 889555 NP_223633.1 CDS jhp0915 NC_000921.1 1013672 1014496 R similar to H. pylori 26695 gene HP0983; hypothetical protein complement(1013672..1014496) Helicobacter pylori J99 889556 NP_223634.1 CDS jhp0916 NC_000921.1 1014636 1014830 R hypothetical protein complement(1014636..1014830) Helicobacter pylori J99 889558 NP_223635.1 CDS virB4_2 NC_000921.1 1015042 1016469 D DNA transfer protein 1015042..1016469 Helicobacter pylori J99 889559 NP_223636.1 CDS virB4_3 NC_000921.1 1016457 1016879 D DNA transfer protein 1016457..1016879 Helicobacter pylori J99 889560 NP_223637.1 CDS topA_2 NC_000921.1 1016916 1018193 D topoisomerase I 1016916..1018193 Helicobacter pylori J99 889561 NP_223638.1 CDS jhp0920 NC_000921.1 1018568 1018849 D hypothetical protein 1018568..1018849 Helicobacter pylori J99 889562 NP_223639.1 CDS jhp0921 NC_000921.1 1018979 1019965 D hypothetical protein 1018979..1019965 Helicobacter pylori J99 889572 NP_223640.1 CDS jhp0922m NC_000921.1 1019965 1021501 D conjugal plasmid transfer system protein join(1019965..1020471,1020473..1021501) Helicobacter pylori J99 889322 NP_223641.1 CDS jhp0924 NC_000921.1 1021498 1022304 D hypothetical protein 1021498..1022304 Helicobacter pylori J99 889564 NP_223642.1 CDS jhp0925 NC_000921.1 1021962 1022549 R hypothetical protein complement(1021962..1022549) Helicobacter pylori J99 889565 NP_223643.1 CDS jhp0926 NC_000921.1 1022556 1023572 R hypothetical protein complement(1022556..1023572) Helicobacter pylori J99 889568 NP_223644.1 CDS jhp0927 NC_000921.1 1023777 1025174 D hypothetical protein 1023777..1025174 Helicobacter pylori J99 889566 NP_223645.1 CDS jhp0928 NC_000921.1 1025324 1032019 D hypothetical protein 1025324..1032019 Helicobacter pylori J99 889567 NP_223646.1 CDS jhp0929 NC_000921.1 1032025 1032477 D hypothetical protein 1032025..1032477 Helicobacter pylori J99 889570 NP_223647.1 CDS jhp0930 NC_000921.1 1032591 1032833 D hypothetical protein 1032591..1032833 Helicobacter pylori J99 889573 NP_223648.1 CDS topA_3 NC_000921.1 1032846 1034906 D topoisomerase I 1032846..1034906 Helicobacter pylori J99 889569 NP_223649.1 CDS jhp0932 NC_000921.1 1034961 1035431 D hypothetical protein 1034961..1035431 Helicobacter pylori J99 889579 NP_223650.1 CDS jhp0933 NC_000921.1 1035401 1036204 D hypothetical protein 1035401..1036204 Helicobacter pylori J99 889577 NP_223651.1 CDS jhp0934 NC_000921.1 1036277 1037296 R hypothetical protein complement(1036277..1037296) Helicobacter pylori J99 889574 NP_223652.1 CDS jhp0935 NC_000921.1 1037343 1037885 R hypothetical protein complement(1037343..1037885) Helicobacter pylori J99 889575 NP_223653.1 CDS jhp0936 NC_000921.1 1038083 1038616 D hypothetical protein 1038083..1038616 Helicobacter pylori J99 889584 NP_223654.1 CDS jhp0937 NC_000921.1 1038613 1039878 D hypothetical protein 1038613..1039878 Helicobacter pylori J99 889589 NP_223655.1 CDS jhp0938 NC_000921.1 1039890 1041140 D similar to H. pylori 26695 gene HP0990; hypothetical protein 1039890..1041140 Helicobacter pylori J99 889576 NP_223656.1 CDS jhp0939 NC_000921.1 1041145 1042158 R similar to H. pylori 26695 gene HP0991; hypothetical protein complement(1041145..1042158) Helicobacter pylori J99 889580 NP_223657.1 CDS jhp0940 NC_000921.1 1042390 1043367 D hypothetical protein 1042390..1043367 Helicobacter pylori J99 889581 NP_223658.1 CDS jhp0941 NC_000921.1 1043684 1044679 R similar to H. pylori 26695 gene HP0995; integrase/recombinase (XERCD family) complement(1043684..1044679) Helicobacter pylori J99 889582 NP_223659.1 CDS jhp0942 NC_000921.1 1045778 1047811 D similar to H. pylori 26695 gene HP0996; hypothetical protein 1045778..1047811 Helicobacter pylori J99 889591 NP_223660.1 CDS jhp0943 NC_000921.1 1048376 1048561 R hypothetical protein complement(1048376..1048561) Helicobacter pylori J99 889583 NP_223661.1 CDS jhp0944 NC_000921.1 1049107 1049874 D hypothetical protein 1049107..1049874 Helicobacter pylori J99 889585 NP_223662.1 CDS jhp0945 NC_000921.1 1049874 1051880 D hypothetical protein 1049874..1051880 Helicobacter pylori J99 889586 NP_223663.1 CDS jhp0946 NC_000921.1 1051673 1052110 D hypothetical protein 1051673..1052110 Helicobacter pylori J99 889587 NP_223664.1 CDS jhp0947 NC_000921.1 1052137 1053537 D hypothetical protein 1052137..1053537 Helicobacter pylori J99 889588 NP_223665.1 CDS jhp0948 NC_000921.1 1053588 1053866 D hypothetical protein 1053588..1053866 Helicobacter pylori J99 889603 NP_223666.1 CDS jhp0949 NC_000921.1 1053868 1055130 D hypothetical protein 1053868..1055130 Helicobacter pylori J99 889596 NP_223667.1 CDS jhp0950 NC_000921.1 1055202 1055885 D hypothetical protein 1055202..1055885 Helicobacter pylori J99 889590 NP_223668.1 CDS jhp0951 NC_000921.1 1055965 1057038 R integrase/recombinase (XERCD family) complement(1055965..1057038) Helicobacter pylori J99 889592 NP_223669.1 CDS jhp0952 NC_000921.1 1061075 1061266 D similar to H. pylori 26695 gene HP0427; hypothetical protein 1061075..1061266 Helicobacter pylori J99 889593 NP_223670.1 CDS jhp0953 NC_000921.1 1061274 1061498 R hypothetical protein complement(1061274..1061498) Helicobacter pylori J99 889594 NP_223671.1 CDS jhp0954 NC_000921.1 1061542 1061982 D hypothetical protein 1061542..1061982 Helicobacter pylori J99 889595 NP_223672.1 CDS jhp0955 NC_000921.1 1062036 1062689 D hypothetical protein 1062036..1062689 Helicobacter pylori J99 889601 NP_223673.1 CDS jhp0956 NC_000921.1 1062798 1063283 D hypothetical protein 1062798..1063283 Helicobacter pylori J99 889597 NP_223674.1 CDS jhp0957 NC_000921.1 1063271 1063873 D hypothetical protein 1063271..1063873 Helicobacter pylori J99 889598 NP_223675.1 CDS jhp0958 NC_000921.1 1064021 1064176 D hypothetical protein 1064021..1064176 Helicobacter pylori J99 889599 NP_223676.1 CDS jhp0959 NC_000921.1 1064262 1064918 D hypothetical protein 1064262..1064918 Helicobacter pylori J99 889600 NP_223677.1 CDS jhp0960 NC_000921.1 1065063 1065281 D hypothetical protein 1065063..1065281 Helicobacter pylori J99 889321 NP_223678.1 CDS jhp0961 NC_000921.1 1065283 1065468 D hypothetical protein 1065283..1065468 Helicobacter pylori J99 889604 NP_223679.1 CDS speA NC_000921.1 1065542 1067389 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(1065542..1067389) Helicobacter pylori J99 889602 NP_223680.1 CDS jhp0963 NC_000921.1 1067403 1068572 R similar to H. pylori 26695 gene HP0421; polysaccharide biosynthesis protein complement(1067403..1068572) Helicobacter pylori J99 889320 NP_223681.1 CDS jhp0964 NC_000921.1 1068577 1069005 R similar to H. pylori 26695 gene HP0420; hypothetical protein complement(1068577..1069005) Helicobacter pylori J99 889606 NP_223682.1 CDS jhp0965 NC_000921.1 1069022 1069807 R similar to H. pylori 26695 gene HP0419; hypothetical protein complement(1069022..1069807) Helicobacter pylori J99 889605 NP_223683.1 CDS jhp0966 NC_000921.1 1069811 1070818 R similar to H. pylori 26695 gene HP0418; hypothetical protein complement(1069811..1070818) Helicobacter pylori J99 889615 NP_223684.1 CDS metG NC_000921.1 1070819 1072789 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1070819..1072789) Helicobacter pylori J99 889607 NP_223685.1 CDS cfa NC_000921.1 1072958 1074127 D similar to H. pylori 26695 gene HP0416; cyclopocyclopropane fatty acid synthase 1072958..1074127 Helicobacter pylori J99 889608 NP_223686.1 CDS jhp0969 NC_000921.1 1074137 1076008 R similar to H. pylori 26695 gene HP0415; hypothetical protein complement(1074137..1076008) Helicobacter pylori J99 889609 NP_223687.1 CDS jhp0970 NC_000921.1 1076573 1076671 R similar to H. pylori 26695 gene HP0412; hypothetical protein complement(1076573..1076671) Helicobacter pylori J99 889610 NP_223688.1 CDS jhp0971 NC_000921.1 1077336 1078085 R similar to H. pylori 26695 gene HP0410; paralog of HpaA complement(1077336..1078085) Helicobacter pylori J99 889611 NP_223689.1 CDS guaA NC_000921.1 1078169 1079695 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1078169..1079695) Helicobacter pylori J99 889612 NP_223690.1 CDS jhp0973 NC_000921.1 1079692 1080186 R similar to H. pylori 26695 gene HP0408; hypothetical protein complement(1079692..1080186) Helicobacter pylori J99 889613 NP_223691.1 CDS jhp0974 NC_000921.1 1080366 1082756 R similar to H. pylori 26695 gene HP0407; S/N-oxide reductase complement(1080366..1082756) Helicobacter pylori J99 889614 NP_223692.1 CDS jhp0975 NC_000921.1 1082860 1083450 R similar to H. pylori 26695 gene HP0406; hypothetical protein complement(1082860..1083450) Helicobacter pylori J99 889617 NP_223693.1 CDS jhp0976 NC_000921.1 1083476 1084798 R similar to H. pylori 26695 gene HP0405; nifS-like protein complement(1083476..1084798) Helicobacter pylori J99 889623 NP_223694.1 CDS jhp0977 NC_000921.1 1084817 1085131 R similar to H. pylori 26695 gene HP0404; HIT family protein complement(1084817..1085131) Helicobacter pylori J99 889616 NP_223695.1 CDS pheS NC_000921.1 1085213 1086199 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1085213..1086199 Helicobacter pylori J99 889618 NP_223696.1 CDS pheT NC_000921.1 1086199 1088493 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1086199..1088493 Helicobacter pylori J99 889619 NP_223697.1 CDS aroA NC_000921.1 1088513 1089802 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1088513..1089802 Helicobacter pylori J99 889631 NP_223698.1 CDS ispH NC_000921.1 1089792 1090616 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1089792..1090616 Helicobacter pylori J99 889621 NP_223699.1 CDS rpsA NC_000921.1 1090738 1092396 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1090738..1092396 Helicobacter pylori J99 889620 NP_223700.1 CDS jhp0983 NC_000921.1 1092425 1092937 D similar to H. pylori 26695 gene HP0398; hypothetical protein 1092425..1092937 Helicobacter pylori J99 889622 NP_223701.1 CDS serA NC_000921.1 1092953 1094527 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1092953..1094527 Helicobacter pylori J99 889632 NP_223702.1 CDS jhp0985 NC_000921.1 1094537 1096387 D similar to H. pylori 26695 gene HP0396; hypothetical protein 1094537..1096387 Helicobacter pylori J99 889624 NP_223703.1 CDS jhp0986 NC_000921.1 1096410 1097078 D similar to H. pylori 26695 gene HP0395; hypothetical protein 1096410..1097078 Helicobacter pylori J99 889625 NP_223704.1 CDS jhp0987 NC_000921.1 1097080 1097838 D similar to H. pylori 26695 gene HP0394; hypothetical protein 1097080..1097838 Helicobacter pylori J99 889626 NP_223705.1 CDS cheV_3 NC_000921.1 1097840 1098778 D similar to H. pylori 26695 gene HP0393; chemotaxis protein 1097840..1098778 Helicobacter pylori J99 889627 NP_223706.1 CDS cheA NC_000921.1 1098835 1101282 D similar to H. pylori 26695 gene HP0392; histidine kinase 1098835..1101282 Helicobacter pylori J99 889628 NP_223707.1 CDS cheW NC_000921.1 1101279 1101776 D similar to H. pylori 26695 gene HP0391; histidine kinase - MCP coupling protein 1101279..1101776 Helicobacter pylori J99 889629 NP_223708.1 CDS tpx NC_000921.1 1102036 1102536 R similar to H. pylori 26695 gene HP0390; thiol peroxidase complement(1102036..1102536) Helicobacter pylori J99 889635 NP_223709.1 CDS sodF NC_000921.1 1102758 1103399 D similar to H. pylori 26695 gene HP0389; iron-dependent superoxide dismutase 1102758..1103399 Helicobacter pylori J99 889630 NP_223710.1 CDS jhp0993 NC_000921.1 1103453 1104184 D similar to H. pylori 26695 gene HP0388; hypothetical protein 1103453..1104184 Helicobacter pylori J99 889633 NP_223711.1 CDS priA NC_000921.1 1104218 1106077 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1104218..1106077) Helicobacter pylori J99 889634 NP_223712.1 CDS jhp0995 NC_000921.1 1106062 1106298 R similar to H. pylori 26695 gene HP0386; hypothetical protein complement(1106062..1106298) Helicobacter pylori J99 889638 NP_223713.1 CDS jhp0996 NC_000921.1 1106311 1106538 R similar to H. pylori 26695 gene HP0385; hypothetical protein complement(1106311..1106538) Helicobacter pylori J99 889276 NP_223714.1 CDS jhp0997 NC_000921.1 1106739 1107485 D similar to H. pylori 26695 gene HP0384; hypothetical protein 1106739..1107485 Helicobacter pylori J99 889636 NP_223715.1 CDS jhp0998 NC_000921.1 1107761 1108285 R similar to H. pylori 26695 gene HP0383; hypothetical protein complement(1107761..1108285) Helicobacter pylori J99 889637 NP_223716.1 CDS jhp0999 NC_000921.1 1108465 1109688 D similar to H. pylori 26695 gene HP0382; zinc-metallo protease 1108465..1109688 Helicobacter pylori J99 889282 NP_223717.1 CDS hemG NC_000921.1 1109685 1110515 D similar to H. pylori 26695 gene HP0381; protoporphyrinogen oxidase 1109685..1110515 Helicobacter pylori J99 889642 NP_223718.1 CDS gdhA NC_000921.1 1110582 1111928 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1110582..1111928 Helicobacter pylori J99 889639 NP_223719.1 CDS fucU NC_000921.1 1111942 1113251 R similar to TIGR HP0379; expression of this protein is predicted to be regulated by slipped-strand repair at both the (C) and the (A) polynucleotide repeats; length of the (A) polynucleotide repeat has been artificially adjusted (addition of one nucleotide) to give the full length protein; alpha-(1,3)-fucosyltransferase complement(join(1111942..1113199,1113199..1113251)) Helicobacter pylori J99 889640 NP_223720.1 CDS jhp1003 NC_000921.1 1113261 1116071 R similar to H. pylori 26695 gene HP0378; cytochrome C-type biogenesis protein complement(1113261..1116071) Helicobacter pylori J99 889654 NP_223721.1 CDS jhp1004 NC_000921.1 1116081 1116752 R similar to H. pylori 26695 gene HP0377; hypothetical protein complement(1116081..1116752) Helicobacter pylori J99 889641 NP_223722.1 CDS hemH NC_000921.1 1116826 1117833 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1116826..1117833) Helicobacter pylori J99 889645 NP_223723.1 CDS jhp1006 NC_000921.1 1117889 1118320 D similar to H. pylori 26695 gene HP0375; hypothetical protein 1117889..1118320 Helicobacter pylori J99 889643 NP_223724.1 CDS jhp1007 NC_000921.1 1118321 1119001 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1118321..1119001 Helicobacter pylori J99 889644 NP_223725.1 CDS jhp1008 NC_000921.1 1119085 1121340 R similar to H. pylori 26695 gene HP0373; hypothetical protein complement(1119085..1121340) Helicobacter pylori J99 889648 NP_223726.1 CDS dcd NC_000921.1 1121509 1122075 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(1121509..1122075) Helicobacter pylori J99 889646 NP_223727.1 CDS accB NC_000921.1 1122205 1122690 D similar to H. pylori 26695 gene HP0371; biotin carboxyl carrier protein 1122205..1122690 Helicobacter pylori J99 889647 NP_223728.1 CDS accC NC_000921.1 1122696 1124063 D biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1122696..1124063 Helicobacter pylori J99 889649 NP_223729.1 CDS jhp1012 NC_000921.1 1124156 1125118 D similar to H. pylori 26695 gene HP0369; type II DNA modification enzyme 1124156..1125118 Helicobacter pylori J99 889650 NP_223730.1 CDS jhp1013 NC_000921.1 1125118 1125666 D similar to H. pylori 26695 gene HP0368; hypothetical protein 1125118..1125666 Helicobacter pylori J99 889651 NP_223731.1 CDS jhp1014 NC_000921.1 1125760 1126365 D similar to H. pylori 26695 gene HP0367; hypothetical protein 1125760..1126365 Helicobacter pylori J99 889652 NP_223732.1 CDS jhp1015 NC_000921.1 1126362 1127498 D similar to H. pylori 26695 gene HP0366; spore coat polysaccharide biosynthesis protein C 1126362..1127498 Helicobacter pylori J99 889675 NP_223733.1 CDS nrdF NC_000921.1 1127804 1128829 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1127804..1128829 Helicobacter pylori J99 889653 NP_223734.1 CDS pcm NC_000921.1 1128839 1129468 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1128839..1129468 Helicobacter pylori J99 889655 NP_223735.1 CDS jhp1018 NC_000921.1 1129490 1130527 D similar to H. pylori 26695 gene HP0362; hypothetical protein 1129490..1130527 Helicobacter pylori J99 889656 NP_223736.1 CDS truA NC_000921.1 1130529 1131257 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1130529..1131257 Helicobacter pylori J99 889659 NP_223737.1 CDS galE NC_000921.1 1131251 1132285 R similar to H. pylori 26695 gene HP0360; UDP-glucose 4-epimerase complement(1131251..1132285) Helicobacter pylori J99 889657 NP_223739.1 CDS jhp1022 NC_000921.1 1133200 1134735 D similar to H. pylori 26695 gene HP0358; hypothetical protein 1133200..1134735 Helicobacter pylori J99 889658 NP_223740.1 CDS jhp1023 NC_000921.1 1134753 1135505 D similar to H. pylori 26695 gene HP0357; short chain alcohol dehydrogenase 1134753..1135505 Helicobacter pylori J99 889661 NP_223741.1 CDS jhp1024 NC_000921.1 1135716 1136588 R similar to H. pylori 26695 gene HP1098; hypothetical protein complement(1135716..1136588) Helicobacter pylori J99 889662 NP_223742.1 CDS eda NC_000921.1 1136658 1137284 R similar to H. pylori 26695 gene HP1099; 2-keto-3-deoxy-6-phosphogluconate aldolase complement(1136658..1137284) Helicobacter pylori J99 889663 NP_223743.1 CDS edd NC_000921.1 1137303 1139129 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1137303..1139129) Helicobacter pylori J99 889668 NP_223744.1 CDS zwf NC_000921.1 1139195 1140472 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1139195..1140472 Helicobacter pylori J99 889664 NP_223745.1 CDS jhp1028 NC_000921.1 1140483 1141166 D similar to H. pylori 26695 gene HP1102; dehydrogenase 1140483..1141166 Helicobacter pylori J99 889665 NP_223746.1 CDS glk NC_000921.1 1141153 1142163 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1141153..1142163 Helicobacter pylori J99 889666 NP_223747.1 CDS jhp1030 NC_000921.1 1142333 1143385 D similar to H. pylori 26695 gene HP1104; zinc-dependent alcohol dehydrogenase 1142333..1143385 Helicobacter pylori J99 889667 NP_223748.1 CDS jhp1031 NC_000921.1 1143388 1144569 R similar to H. pylori 26695 gene HP1105; lipopolysaccharide biosynthesis protein complement(1143388..1144569) Helicobacter pylori J99 889679 NP_223749.1 CDS jhp1032 NC_000921.1 1144709 1145905 R lipopolysaccharide biosynthesis protein complement(1144709..1145905) Helicobacter pylori J99 889669 NP_223750.1 CDS jhp1033 NC_000921.1 1146080 1147387 D similar to H. pylori 26695 gene HP1106; hypothetical protein 1146080..1147387 Helicobacter pylori J99 889670 NP_223751.1 CDS jhp1034 NC_000921.1 1147394 1148056 R similar to H. pylori 26695 gene HP1107; hypothetical protein complement(1147394..1148056) Helicobacter pylori J99 889671 NP_223752.1 CDS porG NC_000921.1 1148339 1148899 D Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; pyruvate flavodoxin oxidoreductase subunit gamma 1148339..1148899 Helicobacter pylori J99 889672 NP_223753.1 CDS porD NC_000921.1 1148915 1149307 D similar to H. pylori 26695 gene HP1109; pyruvate flavodoxin oxidoreductase subunit delta 1148915..1149307 Helicobacter pylori J99 889673 NP_223754.1 CDS porA NC_000921.1 1149317 1150540 D Couples the complete acetyl-CoA oxidation to aromatic ring reduction by the use of the low-potential electron shuttle ferredoxin; pyruvate flavodoxin oxidoreductase subunit alpha 1149317..1150540 Helicobacter pylori J99 889677 NP_223755.1 CDS porB NC_000921.1 1150553 1151497 D Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin; ferrodoxin oxidoreductase subunit beta 1150553..1151497 Helicobacter pylori J99 889674 NP_223756.1 CDS purB NC_000921.1 1151605 1152927 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1151605..1152927 Helicobacter pylori J99 889681 NP_223757.1 CDS jhp1040 NC_000921.1 1153226 1154059 D similar to H. pylori 26695 gene HP1113; hypothetical protein 1153226..1154059 Helicobacter pylori J99 889676 NP_223758.1 CDS uvrB NC_000921.1 1154084 1156060 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1154084..1156060) Helicobacter pylori J99 889678 NP_223759.1 CDS jhp1042 NC_000921.1 1156109 1156912 R similar to H. pylori 26695 gene HP1115; hypothetical protein complement(1156109..1156912) Helicobacter pylori J99 889684 NP_223760.1 CDS jhp1043 NC_000921.1 1156909 1157292 R hypothetical protein complement(1156909..1157292) Helicobacter pylori J99 889682 NP_223761.1 CDS jhp1044 NC_000921.1 1157436 1160900 R similar to H. pylori 26695 gene HP1116; hypothetical protein complement(1157436..1160900) Helicobacter pylori J99 889680 NP_223762.1 CDS jhp1045 NC_000921.1 1161319 1162089 R similar to H. pylori 26695 gene HP1117; hypothetical protein complement(1161319..1162089) Helicobacter pylori J99 889296 NP_223763.1 CDS ggt NC_000921.1 1162333 1164036 R similar to H. pylori 26695 gene HP1118; gamma-glutamyltranspeptidase complement(1162333..1164036) Helicobacter pylori J99 889689 NP_223764.1 CDS flgK NC_000921.1 1164224 1166044 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1164224..1166044) Helicobacter pylori J99 889683 NP_223765.1 CDS jhp1048 NC_000921.1 1166046 1166480 R similar to H. pylori 26695 gene HP1120; hypothetical protein complement(1166046..1166480) Helicobacter pylori J99 889685 NP_223766.1 CDS jhp1049 NC_000921.1 1166559 1167311 R hypothetical protein complement(1166559..1167311) Helicobacter pylori J99 889686 NP_223767.1 CDS jhp1050 NC_000921.1 1167304 1168269 R similar to H. pylori 26695 gene HP1121; type II DNA modification (methyltransferase complement(1167304..1168269) Helicobacter pylori J99 889687 NP_223768.1 CDS jhp1051 NC_000921.1 1168412 1168615 R similar to H. pylori 26695 gene HP1122; hypothetical protein complement(1168412..1168615) Helicobacter pylori J99 889693 NP_223769.1 CDS slyD NC_000921.1 1168925 1169482 R similar to H. pylori 26695 gene HP1123; FKBP-type peptidylprolyl isomerase complement(1168925..1169482) Helicobacter pylori J99 889688 NP_223770.1 CDS jhp1053 NC_000921.1 1169469 1170464 R similar to H. pylori 26695 gene HP1124; hypothetical protein complement(1169469..1170464) Helicobacter pylori J99 889298 NP_223771.1 CDS jhp1054 NC_000921.1 1170472 1171011 R similar to H. pylori 26695 gene HP1125; hypothetical protein complement(1170472..1171011) Helicobacter pylori J99 889695 NP_223772.1 CDS tolB NC_000921.1 1171078 1172331 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1171078..1172331) Helicobacter pylori J99 889692 NP_223773.1 CDS jhp1056 NC_000921.1 1172328 1173119 R similar to H. pylori 26695 gene HP1127 and HP1128; hypothetical protein complement(1172328..1173119) Helicobacter pylori J99 889690 NP_223774.1 CDS exbD_1 NC_000921.1 1173138 1173539 R similar to H. pylori 26695 gene HP1129; biopolymer transport protein complement(1173138..1173539) Helicobacter pylori J99 889691 NP_223775.1 CDS exbB_1 NC_000921.1 1173591 1174160 R similar to H. pylori 26695 gene HP1130; biopolymer transport protein complement(1173591..1174160) Helicobacter pylori J99 889696 NP_223776.1 CDS atpC NC_000921.1 1174171 1174542 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(1174171..1174542) Helicobacter pylori J99 889704 NP_223777.1 CDS atpD NC_000921.1 1174553 1175962 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(1174553..1175962) Helicobacter pylori J99 889694 NP_223778.1 CDS atpG NC_000921.1 1175987 1176892 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(1175987..1176892) Helicobacter pylori J99 889697 NP_223779.1 CDS atpA NC_000921.1 1176907 1178418 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(1176907..1178418) Helicobacter pylori J99 889698 NP_223780.1 CDS atpH NC_000921.1 1178441 1178983 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(1178441..1178983) Helicobacter pylori J99 889699 NP_223781.1 CDS atpF NC_000921.1 1178984 1179499 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(1178984..1179499) Helicobacter pylori J99 889700 NP_223782.1 CDS atpX NC_000921.1 1179503 1179937 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; ATP synthase F0F1 subunit B' complement(1179503..1179937) Helicobacter pylori J99 889701 NP_223783.1 CDS jhp1066 NC_000921.1 1180042 1180914 R similar to H. pylori 26695 gene HP1138; plasmid replication-partition related protein complement(1180042..1180914) Helicobacter pylori J99 889702 NP_223784.1 CDS jhp1067 NC_000921.1 1180917 1181711 R similar to H. pylori 26695 gene HP1139; hypothetical protein complement(1180917..1181711) Helicobacter pylori J99 889720 NP_223785.1 CDS jhp1068 NC_000921.1 1181714 1182352 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(1181714..1182352) Helicobacter pylori J99 889703 NP_223786.1 CDS fmt NC_000921.1 1182349 1183266 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1182349..1183266) Helicobacter pylori J99 889705 NP_223787.1 CDS jhp1070 NC_000921.1 1183290 1185569 R similar to H. pylori 26695 gene HP1142; hypothetical protein complement(1183290..1185569) Helicobacter pylori J99 889706 NP_223788.1 CDS jhp1071 NC_000921.1 1185604 1186905 R similar to H. pylori 26695 gene HP1143; hypothetical protein complement(1185604..1186905) Helicobacter pylori J99 889707 NP_223789.1 CDS jhp1072 NC_000921.1 1187115 1187408 D similar to H. pylori 26695 gene HP1144; hypothetical protein 1187115..1187408 Helicobacter pylori J99 889708 NP_223790.1 CDS jhp1073 NC_000921.1 1190266 1191123 R similar to H. pylori 26695 gene HP1145 and HP1146; hypothetical protein complement(1190266..1191123) Helicobacter pylori J99 889709 NP_223791.1 CDS rplS NC_000921.1 1191976 1192332 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1191976..1192332) Helicobacter pylori J99 889710 NP_223792.1 CDS trmD NC_000921.1 1192354 1193043 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1192354..1193043) Helicobacter pylori J99 889711 NP_223793.1 CDS rimM NC_000921.1 1193044 1193589 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1193044..1193589) Helicobacter pylori J99 889712 NP_223794.1 CDS jhp1077 NC_000921.1 1193599 1193952 R similar to H. pylori 26695 gene HP1150; hypothetical protein complement(1193599..1193952) Helicobacter pylori J99 889713 NP_223795.1 CDS rpsP NC_000921.1 1193969 1194199 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1193969..1194199) Helicobacter pylori J99 889714 NP_223796.1 CDS ffh NC_000921.1 1194273 1195619 R similar to H. pylori 26695 gene HP1152; signal recognition particle protein complement(1194273..1195619) Helicobacter pylori J99 889717 NP_223797.1 CDS valS NC_000921.1 1195634 1198252 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1195634..1198252) Helicobacter pylori J99 889715 NP_223798.1 CDS jhp1081 NC_000921.1 1198390 1198797 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1198390..1198797 Helicobacter pylori J99 889716 NP_223799.1 CDS murG NC_000921.1 1198809 1199870 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1198809..1199870 Helicobacter pylori J99 889722 NP_223800.1 CDS jhp1083 NC_000921.1 1199979 1202072 D similar to H. pylori 26695 gene HP1156; hypothetical protein 1199979..1202072 Helicobacter pylori J99 889719 NP_223801.1 CDS jhp1084 NC_000921.1 1202095 1205808 D similar to H. pylori 26695 gene HP1157; hypothetical protein 1202095..1205808 Helicobacter pylori J99 889718 NP_223802.1 CDS proC NC_000921.1 1205822 1206595 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1205822..1206595 Helicobacter pylori J99 889724 NP_223803.1 CDS fic NC_000921.1 1206622 1207149 D similar to H. pylori 26695 gene HP1159; cAMP-induced cell filamentation protein 1206622..1207149 Helicobacter pylori J99 889721 NP_223804.1 CDS jhp1087 NC_000921.1 1207235 1207660 R similar to H. pylori 26695 gene HP1160; metalloprotease complement(1207235..1207660) Helicobacter pylori J99 889729 NP_223805.1 CDS fldA NC_000921.1 1207715 1208209 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(1207715..1208209) Helicobacter pylori J99 889723 NP_223806.1 CDS jhp1089 NC_000921.1 1208301 1208882 R similar to H. pylori 26695 gene HP1162; hypothetical protein complement(1208301..1208882) Helicobacter pylori J99 889731 NP_223807.1 CDS fixS NC_000921.1 1209007 1209198 D similar to H. pylori 26695 gene HP1163; component of cation transport for cbb3-type oxidase 1209007..1209198 Helicobacter pylori J99 889725 NP_223808.1 CDS trxB_2 NC_000921.1 1209224 1210198 D similar to H. pylori 26695 gene HP1164; thioredoxin reductase 1209224..1210198 Helicobacter pylori J99 889728 NP_223809.1 CDS jhp1092 NC_000921.1 1210206 1211366 R similar to H. pylori 26695 gene HP1165; hypothetical protein complement(1210206..1211366) Helicobacter pylori J99 889726 NP_223810.1 CDS pgi NC_000921.1 1211430 1213067 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1211430..1213067 Helicobacter pylori J99 889727 NP_223811.1 CDS jhp1094 NC_000921.1 1213371 1214786 D similar to H. pylori 26695 gene HP1167; hypothetical protein 1213371..1214786 Helicobacter pylori J99 889743 NP_223812.1 CDS jhp1095 NC_000921.1 1215246 1217309 R similar to H. pylori 26695 gene HP1168; hypothetical protein complement(1215246..1217309) Helicobacter pylori J99 889737 NP_223813.1 CDS jhp1096 NC_000921.1 1217517 1218170 D similar to H. pylori 26695 gene HP1169; amino acid ABC transporter permease 1217517..1218170 Helicobacter pylori J99 889730 NP_223814.1 CDS jhp1097 NC_000921.1 1218172 1218843 D similar to H. pylori 26695 gene HP1170; amino acid ABC transporter permease 1218172..1218843 Helicobacter pylori J99 889732 NP_223815.1 CDS jhp1098 NC_000921.1 1218845 1219591 D similar to H. pylori 26695 gene HP1171; amino acid ABC transporter ATP-binding protein 1218845..1219591 Helicobacter pylori J99 889733 NP_223816.1 CDS jhp1099 NC_000921.1 1219640 1220473 D similar to H. pylori 26695 gene HP1172; amino acid ABC transporter 1219640..1220473 Helicobacter pylori J99 889734 NP_223817.1 CDS jhp1100 NC_000921.1 1220595 1221152 D similar to H. pylori 26695 gene HP1173; hypothetical protein 1220595..1221152 Helicobacter pylori J99 889735 NP_223818.1 CDS gluP NC_000921.1 1221423 1222646 R similar to H. pylori 26695 gene HP1174; glucose/galactose transporter complement(1221423..1222646) Helicobacter pylori J99 889736 NP_223819.1 CDS jhp1102 NC_000921.1 1222775 1224082 R similar to H. pylori 26695 gene HP1175; hypothetical protein complement(1222775..1224082) Helicobacter pylori J99 889738 NP_223820.1 CDS jhp1103 NC_000921.1 1224524 1226455 R similar to H. pylori 26695 gene HP1177; Outer membrane function complement(1224524..1226455) Helicobacter pylori J99 889739 NP_223821.1 CDS deoD NC_000921.1 1226918 1227619 R similar to H. pylori 26695 gene HP1178; purine nucleoside phosphorylase complement(1226918..1227619) Helicobacter pylori J99 889740 NP_223822.1 CDS deoB NC_000921.1 1227616 1228857 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1227616..1228857) Helicobacter pylori J99 889741 NP_223823.1 CDS jhp1106 NC_000921.1 1228869 1230125 R similar to H. pylori 26695 gene HP1180; nucleoside transporter complement(1228869..1230125) Helicobacter pylori J99 889751 NP_223824.1 CDS jhp1107 NC_000921.1 1230455 1231786 D similar to H. pylori 26695 gene HP1181; multidrug ABC transporter 1230455..1231786 Helicobacter pylori J99 889742 NP_223825.1 CDS jhp1108 NC_000921.1 1231802 1232563 D similar to H. pylori 26695 gene HP1182; hypothetical protein 1231802..1232563 Helicobacter pylori J99 889750 NP_223826.1 CDS jhp1109 NC_000921.1 1232568 1233719 R similar to H. pylori 26695 gene HP1183; Na+/H+ antiporter complement(1232568..1233719) Helicobacter pylori J99 889744 NP_223827.1 CDS jhp1110 NC_000921.1 1233745 1235124 R similar to H. pylori 26695 gene HP1184; hypothetical protein complement(1233745..1235124) Helicobacter pylori J99 889745 NP_223828.1 CDS jhp1111 NC_000921.1 1235294 1236469 R similar to H. pylori 26695 gene HP1185; sugar efflux transporter complement(1235294..1236469) Helicobacter pylori J99 889746 NP_223829.1 CDS jhp1112 NC_000921.1 1236741 1237484 D similar to H. pylori 26695 gene HP1186; carbonic anhydrase 1236741..1237484 Helicobacter pylori J99 889747 NP_223830.1 CDS jhp1113 NC_000921.1 1237715 1238866 R similar to H. pylori 26695 gene HP1187; hypothetical protein complement(1237715..1238866) Helicobacter pylori J99 889748 NP_223831.1 CDS asd NC_000921.1 1239301 1240341 R similar to H. pylori 26695 gene HP1189; aspartate-semialdehyde dehydrogenase complement(1239301..1240341) Helicobacter pylori J99 889756 NP_223832.1 CDS hisS NC_000921.1 1240328 1241656 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1240328..1241656) Helicobacter pylori J99 889749 NP_223833.1 CDS waaF NC_000921.1 1241718 1242767 D similar to H. pylori 26695 gene HP1191; ADP-heptose--LPS heptosyltransferase II 1241718..1242767 Helicobacter pylori J99 889772 NP_223834.1 CDS jhp1117 NC_000921.1 1242951 1243115 R similar to H. pylori 26695 gene HP1192; motility protein complement(1242951..1243115) Helicobacter pylori J99 889752 NP_223835.1 CDS fusA NC_000921.1 1243658 1245736 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1243658..1245736) Helicobacter pylori J99 889753 NP_223836.1 CDS rpsG NC_000921.1 1245748 1246215 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1245748..1246215) Helicobacter pylori J99 889754 NP_223837.1 CDS rpsL NC_000921.1 1246231 1246638 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1246231..1246638) Helicobacter pylori J99 889755 NP_223838.1 CDS rpoB NC_000921.1 1246726 1255398 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' complement(1246726..1255398) Helicobacter pylori J99 889766 NP_223839.1 CDS rplL NC_000921.1 1255620 1255997 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1255620..1255997) Helicobacter pylori J99 889757 NP_223840.1 CDS rplJ NC_000921.1 1256040 1256534 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1256040..1256534) Helicobacter pylori J99 889758 NP_223841.1 CDS rplA NC_000921.1 1256643 1257347 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1256643..1257347) Helicobacter pylori J99 889759 NP_223842.1 CDS rplK NC_000921.1 1257392 1257817 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1257392..1257817) Helicobacter pylori J99 889760 NP_223843.1 CDS nusG NC_000921.1 1257835 1258365 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1257835..1258365) Helicobacter pylori J99 889761 NP_223844.1 CDS secE NC_000921.1 1258392 1258571 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1258392..1258571) Helicobacter pylori J99 889336 NP_223845.1 CDS rpmG NC_000921.1 1258818 1258976 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1258818..1258976) Helicobacter pylori J99 889762 NP_223846.1 CDS tuf NC_000921.1 1259023 1260222 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1259023..1260222) Helicobacter pylori J99 889765 NP_223847.1 CDS jhp1129 NC_000921.1 1260926 1262662 D similar to H. pylori 26695 gene HP1206; ABC transporter ATP-binding protein 1260926..1262662 Helicobacter pylori J99 889763 NP_223848.1 CDS jhp1130 NC_000921.1 1262671 1263339 R similar to H. pylori 26695 gene HP1207; hypothetical protein complement(1262671..1263339) Helicobacter pylori J99 889764 NP_223849.1 CDS M.HpyI NC_000921.1 1263527 1264516 R similar to H. pylori 26695 gene HP1208; type II DNA modification (methyltransferase complement(1263527..1264516) Helicobacter pylori J99 889767 NP_223850.1 CDS jhp1132 NC_000921.1 1264845 1265024 R hypothetical protein complement(1264845..1265024) Helicobacter pylori J99 889769 NP_223851.1 CDS cysE NC_000921.1 1265253 1265768 R similar to H. pylori 26695 gene HP1210; O-serine acetyltransferase complement(1265253..1265768) Helicobacter pylori J99 889768 NP_223853.1 CDS atpE NC_000921.1 1266365 1266682 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(1266365..1266682) Helicobacter pylori J99 889771 NP_223854.1 CDS pnp NC_000921.1 1266815 1268881 R similar to H. pylori 26695 gene HP1213; polynucleotide phosphorylase complement(1266815..1268881) Helicobacter pylori J99 889775 NP_223855.1 CDS jhp1137 NC_000921.1 1268884 1269588 R similar to H. pylori 26695 gene HP1214; hypothetical protein complement(1268884..1269588) Helicobacter pylori J99 889780 NP_223856.1 CDS imp NC_000921.1 1269602 1271902 R similar to H. pylori 26695 gene HP1215 and HP1216; role in outermembrane permeability complement(1269602..1271902) Helicobacter pylori J99 889773 NP_223857.1 CDS jhp1139 NC_000921.1 1271865 1272344 R similar to H. pylori 26695 gene HP1217; hypothetical protein complement(1271865..1272344) Helicobacter pylori J99 889779 NP_223858.1 CDS purD NC_000921.1 1272393 1273667 R similar to H. pylori 26695 gene HP1218; glycinamide ribonucleotide synthetase complement(1272393..1273667) Helicobacter pylori J99 889774 NP_223859.1 CDS jhp1141 NC_000921.1 1273981 1274667 R similar to H. pylori 26695 gene HP1220; ABC transporter ATP-binding protein complement(1273981..1274667) Helicobacter pylori J99 889776 NP_223860.1 CDS jhp1142 NC_000921.1 1274661 1275365 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1274661..1275365) Helicobacter pylori J99 889777 NP_223861.1 CDS dld NC_000921.1 1275405 1278245 R similar to H. pylori 26695 gene HP1222; D-lactate dehydrogenase complement(1275405..1278245) Helicobacter pylori J99 889778 NP_223862.1 CDS jhp1144 NC_000921.1 1278317 1278655 D similar to H. pylori 26695 gene HP1223; hypothetical protein 1278317..1278655 Helicobacter pylori J99 889784 NP_223863.1 CDS hemD NC_000921.1 1278658 1279329 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1278658..1279329 Helicobacter pylori J99 889792 NP_223864.1 CDS jhp1146 NC_000921.1 1279386 1279778 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1279386..1279778 Helicobacter pylori J99 889781 NP_223865.1 CDS hemN_2 NC_000921.1 1279829 1280866 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1279829..1280866) Helicobacter pylori J99 889782 NP_223866.1 CDS jhp1148 NC_000921.1 1280962 1281252 D similar to H. pylori 26695 gene HP1227; periplasmic cytochrome C-553 1280962..1281252 Helicobacter pylori J99 889783 NP_223867.1 CDS mutT NC_000921.1 1281413 1281886 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1281413..1281886 Helicobacter pylori J99 889787 NP_223868.1 CDS lysC NC_000921.1 1281880 1283097 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1281880..1283097 Helicobacter pylori J99 889810 NP_223869.1 CDS jhp1151 NC_000921.1 1283094 1283636 D similar to H. pylori 26695 gene HP1230; hypothetical protein 1283094..1283636 Helicobacter pylori J99 889785 NP_223870.1 CDS holB NC_000921.1 1283633 1284289 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1283633..1284289 Helicobacter pylori J99 889786 NP_223871.1 CDS folP NC_000921.1 1284286 1285428 D similar to H. pylori 26695 gene HP1232; dihydropteroate synthase 1284286..1285428 Helicobacter pylori J99 889788 NP_223872.1 CDS jhp1154 NC_000921.1 1285523 1285984 R similar to H. pylori 26695 gene HP1233; hypothetical protein complement(1285523..1285984) Helicobacter pylori J99 889789 NP_223873.1 CDS jhp1155 NC_000921.1 1286335 1287231 D similar to H. pylori 26695 gene HP1234; hypothetical protein 1286335..1287231 Helicobacter pylori J99 889790 NP_223874.1 CDS jhp1156 NC_000921.1 1287235 1288482 D similar to H. pylori 26695 gene HP1235; hypothetical protein 1287235..1288482 Helicobacter pylori J99 889804 NP_223875.1 CDS jhp1157 NC_000921.1 1288561 1289112 D similar to H. pylori 26695 gene HP1236; hypothetical protein 1288561..1289112 Helicobacter pylori J99 889791 NP_223876.1 CDS carA NC_000921.1 1289112 1290239 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1289112..1290239 Helicobacter pylori J99 889793 NP_223877.1 CDS amiF NC_000921.1 1290408 1291412 D formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1290408..1291412 Helicobacter pylori J99 889794 NP_223878.1 CDS jhp1160 NC_000921.1 1291895 1292305 R hypothetical protein complement(1291895..1292305) Helicobacter pylori J99 889795 NP_223879.1 CDS maf NC_000921.1 1292482 1293054 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1292482..1293054) Helicobacter pylori J99 889796 NP_223880.1 CDS alaS NC_000921.1 1293056 1295599 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1293056..1295599) Helicobacter pylori J99 889797 NP_223881.1 CDS jhp1163 NC_000921.1 1295719 1295949 D similar to H. pylori 26695 gene HP1242; hypothetical protein 1295719..1295949 Helicobacter pylori J99 889798 NP_223882.1 CDS babB NC_000921.1 1296915 1299026 R similar to H. pylori 26695 gene HP0896; hypothetical protein complement(1296915..1299026) Helicobacter pylori J99 889799 NP_223883.1 CDS rpsR NC_000921.1 1299303 1299560 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1299303..1299560) Helicobacter pylori J99 889800 NP_223884.1 CDS ssb NC_000921.1 1299583 1300128 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1299583..1300128) Helicobacter pylori J99 889812 NP_223885.1 CDS rpsF NC_000921.1 1300143 1300571 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1300143..1300571) Helicobacter pylori J99 889801 NP_223886.1 CDS jhp1168 NC_000921.1 1300700 1301722 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(1300700..1301722) Helicobacter pylori J99 889802 NP_223887.1 CDS vacB NC_000921.1 1301712 1303646 R similar to H. pylori 26695 gene HP1248; ribonuclease II family protein complement(1301712..1303646) Helicobacter pylori J99 889803 NP_223888.1 CDS aroE NC_000921.1 1303646 1304446 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1303646..1304446) Helicobacter pylori J99 889805 NP_223889.1 CDS jhp1171 NC_000921.1 1304454 1305113 R similar to H. pylori 26695 gene HP1250; hypothetical protein complement(1304454..1305113) Helicobacter pylori J99 889807 NP_223890.1 CDS jhp1172 NC_000921.1 1305122 1306168 R similar to H. pylori 26695 gene HP1251; peptide ABC transporter ATP-binding protein complement(1305122..1306168) Helicobacter pylori J99 889817 NP_223891.1 CDS jhp1173 NC_000921.1 1306165 1307952 R similar to H. pylori 26695 gene HP1252; hypothetical protein complement(1306165..1307952) Helicobacter pylori J99 889806 NP_223892.1 CDS trpS NC_000921.1 1307953 1308933 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1307953..1308933) Helicobacter pylori J99 889808 NP_223893.1 CDS jhp1175 NC_000921.1 1309005 1309742 R similar to H. pylori 26695 gene HP1254; hypothetical protein complement(1309005..1309742) Helicobacter pylori J99 889809 NP_223894.1 CDS secG NC_000921.1 1309875 1310471 D similar to H. pylori 26695 gene HP1255; preprotein translocase subunit SecG 1309875..1310471 Helicobacter pylori J99 889820 NP_223895.1 CDS frr NC_000921.1 1310471 1311028 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1310471..1311028 Helicobacter pylori J99 890458 NP_223896.1 CDS pyrE NC_000921.1 1311032 1311637 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1311032..1311637 Helicobacter pylori J99 889811 NP_223897.1 CDS jhp1179 NC_000921.1 1311627 1312085 D similar to H. pylori 26695 gene HP1258; hypothetical protein 1311627..1312085 Helicobacter pylori J99 889813 NP_223898.1 CDS jhp1180 NC_000921.1 1312082 1312786 D similar to H. pylori 26695 gene HP1259; hypothetical protein 1312082..1312786 Helicobacter pylori J99 889814 NP_223899.1 CDS nuoA NC_000921.1 1312879 1313280 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1312879..1313280 Helicobacter pylori J99 889815 NP_223900.1 CDS nuoB NC_000921.1 1313280 1313759 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1313280..1313759 Helicobacter pylori J99 889823 NP_223901.1 CDS nuoC NC_000921.1 1313759 1314556 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1313759..1314556 Helicobacter pylori J99 890452 NP_223902.1 CDS nuoD NC_000921.1 1314558 1315787 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1314558..1315787 Helicobacter pylori J99 889816 NP_223903.1 CDS nuoE NC_000921.1 1315784 1316014 D similar to H. pylori 26695 gene HP1264; NADH oxidoreductase I 1315784..1316014 Helicobacter pylori J99 889818 NP_223904.1 CDS nuoF NC_000921.1 1316017 1317003 D similar to H. pylori 26695 gene HP1265; NADH oxidoreductase I 1316017..1317003 Helicobacter pylori J99 890462 NP_223905.1 CDS nuoG NC_000921.1 1317000 1319549 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1317000..1319549 Helicobacter pylori J99 889822 NP_223906.1 CDS nuoH NC_000921.1 1319546 1320535 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1319546..1320535 Helicobacter pylori J99 890456 NP_223907.1 CDS nuoI NC_000921.1 1320545 1321207 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1320545..1321207 Helicobacter pylori J99 889819 NP_223908.1 CDS nuoJ NC_000921.1 1321200 1321748 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1321200..1321748 Helicobacter pylori J99 890460 NP_223909.1 CDS nuoK NC_000921.1 1321745 1322047 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1321745..1322047 Helicobacter pylori J99 889821 NP_223910.1 CDS nuoL NC_000921.1 1322050 1323888 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1322050..1323888 Helicobacter pylori J99 890459 NP_223911.1 CDS nuoM NC_000921.1 1323892 1325430 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1323892..1325430 Helicobacter pylori J99 889824 NP_223912.1 CDS nuoN NC_000921.1 1325417 1326895 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1325417..1326895 Helicobacter pylori J99 890455 NP_223913.1 CDS pflA NC_000921.1 1326885 1329296 D similar to H. pylori 26695 gene HP1274; flagellar functional protein 1326885..1329296 Helicobacter pylori J99 889830 NP_223914.1 CDS jhp1196 NC_000921.1 1329298 1330677 D similar to H. pylori 26695 gene HP1275; phosphomannomutase 1329298..1330677 Helicobacter pylori J99 890445 NP_223915.1 CDS jhp1197 NC_000921.1 1330858 1331229 D similar to H. pylori 26695 gene HP1276; hypothetical protein 1330858..1331229 Helicobacter pylori J99 889825 NP_223916.1 CDS trpA NC_000921.1 1331406 1332194 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1331406..1332194) Helicobacter pylori J99 890451 NP_223917.1 CDS trpB NC_000921.1 1332191 1333372 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1332191..1333372) Helicobacter pylori J99 889826 NP_223918.1 CDS trpC NC_000921.1 1333374 1334732 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1333374..1334732) Helicobacter pylori J99 890448 NP_223919.1 CDS trpD NC_000921.1 1334725 1335732 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1334725..1335732) Helicobacter pylori J99 889827 NP_223920.1 CDS trpG NC_000921.1 1335729 1336313 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1335729..1336313) Helicobacter pylori J99 890454 NP_223921.1 CDS trpE NC_000921.1 1336310 1337812 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1336310..1337812) Helicobacter pylori J99 889828 NP_223922.1 CDS jhp1204 NC_000921.1 1338041 1339099 R similar to H. pylori 26695 gene HP1284; hypothetical protein complement(1338041..1339099) Helicobacter pylori J99 890450 NP_223923.1 CDS jhp1205 NC_000921.1 1339167 1339904 R similar to H. pylori 26695 gene HP1285; hypothetical protein complement(1339167..1339904) Helicobacter pylori J99 889863 NP_223924.1 CDS jhp1206 NC_000921.1 1340027 1340575 D similar to H. pylori 26695 gene HP1286; hypothetical protein 1340027..1340575 Helicobacter pylori J99 890389 NP_223925.1 CDS jhp1207 NC_000921.1 1340639 1341292 R similar to H. pylori 26695 gene HP1287; transcriptional regulator complement(1340639..1341292) Helicobacter pylori J99 889829 NP_223926.1 CDS jhp1208 NC_000921.1 1342003 1342356 D similar to H. pylori 26695 gene HP1288; hypothetical protein 1342003..1342356 Helicobacter pylori J99 890446 NP_223927.1 CDS jhp1209 NC_000921.1 1342380 1342865 D similar to H. pylori 26695 gene HP1289; hypothetical protein 1342380..1342865 Helicobacter pylori J99 889831 NP_223928.1 CDS pnuC NC_000921.1 1343051 1343713 D similar to H. pylori 26695 gene HP1290; nicotinamide mononucleotide transporter 1343051..1343713 Helicobacter pylori J99 890442 NP_223929.1 CDS jhp1211 NC_000921.1 1343701 1344315 D similar to H. pylori 26695 gene HP1291; hypothetical protein 1343701..1344315 Helicobacter pylori J99 889834 NP_223930.1 CDS rplQ NC_000921.1 1345094 1345444 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1345094..1345444) Helicobacter pylori J99 890439 NP_223931.1 CDS rpoA NC_000921.1 1345444 1346478 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1345444..1346478) Helicobacter pylori J99 889832 NP_223932.1 CDS rpsD NC_000921.1 1346490 1347116 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1346490..1347116) Helicobacter pylori J99 890434 NP_223933.1 CDS rpsK NC_000921.1 1347126 1347521 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1347126..1347521) Helicobacter pylori J99 889842 NP_223934.1 CDS rpsM NC_000921.1 1347544 1347906 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1347544..1347906) Helicobacter pylori J99 890423 NP_223935.1 CDS rpmJ NC_000921.1 1347910 1348023 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(1347910..1348023) Helicobacter pylori J99 889833 NP_223936.1 CDS infA NC_000921.1 1348102 1348320 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1348102..1348320) Helicobacter pylori J99 890438 NP_223937.1 CDS map NC_000921.1 1348320 1349081 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1348320..1349081) Helicobacter pylori J99 889835 NP_223938.1 CDS secY NC_000921.1 1349081 1350343 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1349081..1350343) Helicobacter pylori J99 890436 NP_223939.1 CDS rplO NC_000921.1 1350378 1350779 R late assembly protein; 50S ribosomal protein L15 complement(1350378..1350779) Helicobacter pylori J99 889836 NP_223940.2 CDS rpsE NC_000921.1 1350797 1351240 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1350797..1351240) Helicobacter pylori J99 890433 NP_223941.1 CDS rplR NC_000921.1 1351255 1351611 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1351255..1351611) Helicobacter pylori J99 889837 NP_223942.1 CDS rplF NC_000921.1 1351625 1352161 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1351625..1352161) Helicobacter pylori J99 890435 NP_223943.1 CDS rpsH NC_000921.1 1352173 1352568 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1352173..1352568) Helicobacter pylori J99 889838 NP_223944.1 CDS rpsN NC_000921.1 1352578 1352763 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 complement(1352578..1352763) Helicobacter pylori J99 890431 NP_223945.1 CDS rplE NC_000921.1 1352773 1353318 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1352773..1353318) Helicobacter pylori J99 889839 NP_223946.1 CDS rplX NC_000921.1 1353332 1353553 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1353332..1353553) Helicobacter pylori J99 890426 NP_223947.1 CDS rplN NC_000921.1 1353553 1353921 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1353553..1353921) Helicobacter pylori J99 889840 NP_223948.1 CDS rpsQ NC_000921.1 1353924 1354184 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1353924..1354184) Helicobacter pylori J99 890420 NP_223949.1 CDS rpmC NC_000921.1 1354198 1354398 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1354198..1354398) Helicobacter pylori J99 889841 NP_223950.1 CDS rplP NC_000921.1 1354385 1354810 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1354385..1354810) Helicobacter pylori J99 890424 NP_223951.1 CDS rpsC NC_000921.1 1354813 1355517 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1354813..1355517) Helicobacter pylori J99 889843 NP_223952.1 CDS rplV NC_000921.1 1355521 1355889 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1355521..1355889) Helicobacter pylori J99 890421 NP_223953.1 CDS rpsS NC_000921.1 1355899 1356180 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1355899..1356180) Helicobacter pylori J99 889851 NP_223954.1 CDS rplB NC_000921.1 1356192 1357022 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1356192..1357022) Helicobacter pylori J99 889844 NP_223955.1 CDS rplW NC_000921.1 1357038 1357319 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1357038..1357319) Helicobacter pylori J99 890422 NP_223956.1 CDS rplD NC_000921.1 1357323 1357970 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1357323..1357970) Helicobacter pylori J99 889845 NP_223957.1 CDS rplC NC_000921.1 1358005 1358580 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1358005..1358580) Helicobacter pylori J99 890418 NP_223958.1 CDS rpsJ NC_000921.1 1358617 1358931 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1358617..1358931) Helicobacter pylori J99 889846 NP_223959.1 CDS jhp1241 NC_000921.1 1359097 1360227 D similar to H. pylori 26695 gene HP1321; hypothetical protein 1359097..1360227 Helicobacter pylori J99 890416 NP_223960.1 CDS jhp1242 NC_000921.1 1360492 1361070 D similar to H. pylori 26695 gene HP1322; hypothetical protein 1360492..1361070 Helicobacter pylori J99 889847 NP_223961.1 CDS rnhB NC_000921.1 1361044 1361673 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1361044..1361673) Helicobacter pylori J99 890412 NP_223962.1 CDS jhp1244 NC_000921.1 1361689 1361883 R similar to H. pylori 26695 gene HP1324; hypothetical protein complement(1361689..1361883) Helicobacter pylori J99 889848 NP_223963.1 CDS fumC NC_000921.1 1361964 1363355 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1361964..1363355) Helicobacter pylori J99 890413 NP_223964.1 CDS jhp1246 NC_000921.1 1363530 1363907 D similar to H. pylori 26695 gene HP1326; hypothetical protein 1363530..1363907 Helicobacter pylori J99 889849 NP_223965.1 CDS jhp1247 NC_000921.1 1363912 1365150 D similar to H. pylori 26695 gene HP1327; hypothetical protein 1363912..1365150 Helicobacter pylori J99 890399 NP_223966.1 CDS czcB_2 NC_000921.1 1365147 1366172 D similar to H. pylori 26695 gene HP1328; cation efflux system protein 1365147..1366172 Helicobacter pylori J99 889850 NP_223967.1 CDS czcA_2 NC_000921.1 1366173 1369280 D similar to H. pylori 26695 gene HP1329; cation efflux system protein 1366173..1369280 Helicobacter pylori J99 890409 NP_223968.1 CDS jhp1250 NC_000921.1 1369261 1369617 R similar to H. pylori 26695 gene HP1330; hypothetical protein complement(1369261..1369617) Helicobacter pylori J99 889852 NP_223969.1 CDS jhp1251 NC_000921.1 1369611 1370297 R similar to H. pylori 26695 gene HP1331; hypothetical protein complement(1369611..1370297) Helicobacter pylori J99 890407 NP_223970.1 CDS dnaJ_2 NC_000921.1 1370308 1371417 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ complement(1370308..1371417) Helicobacter pylori J99 889855 NP_223971.1 CDS jhp1253 NC_000921.1 1371542 1372672 D similar to H. pylori 26695 gene HP1333; hypothetical protein 1371542..1372672 Helicobacter pylori J99 890402 NP_223972.2 CDS mnmA NC_000921.1 1372714 1373742 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1372714..1373742) Helicobacter pylori J99 889853 NP_223973.1 CDS jhp1255 NC_000921.1 1373882 1374643 D similar to H. pylori 26695 gene HP1336; hypothetical protein 1373882..1374643 Helicobacter pylori J99 890408 NP_223974.1 CDS jhp1256 NC_000921.1 1374640 1375164 R similar to H. pylori 26695 gene HP1337; hypothetical protein complement(1374640..1375164) Helicobacter pylori J99 889854 NP_223975.1 CDS jhp1257 NC_000921.1 1375148 1375594 R Inhibits transcription at high concentrations of nickel; nickel responsive regulator complement(1375148..1375594) Helicobacter pylori J99 890405 NP_223976.1 CDS exbB_2 NC_000921.1 1375917 1376354 D similar to H. pylori 26695 gene HP1339; biopolymer transport protein 1375917..1376354 Helicobacter pylori J99 889860 NP_223977.1 CDS exbD_2 NC_000921.1 1376351 1376740 D similar to H. pylori 26695 gene HP1340; biopolymer transport EXBD protein 1376351..1376740 Helicobacter pylori J99 890397 NP_223978.1 CDS tonB_2 NC_000921.1 1376706 1377548 D similar to H. pylori 26695 gene HP1341; siderophore-mediated iron transport protein 1376706..1377548 Helicobacter pylori J99 889856 NP_223979.1 CDS jhp1261 NC_000921.1 1377733 1379823 D similar to H. pylori 26695 gene HP1342; hypothetical protein 1377733..1379823 Helicobacter pylori J99 890404 NP_223980.1 CDS jhp1262 NC_000921.1 1379941 1380669 R similar to H. pylori 26695 gene HP1343; hypothetical protein complement(1379941..1380669) Helicobacter pylori J99 889857 NP_223981.1 CDS corA NC_000921.1 1380676 1381632 R similar to H. pylori 26695 gene HP1344; magnesium/cobalt transporter CorA complement(1380676..1381632) Helicobacter pylori J99 890398 NP_223982.1 CDS pgk NC_000921.1 1381648 1382856 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1381648..1382856) Helicobacter pylori J99 889858 NP_223983.1 CDS gap_2 NC_000921.1 1382871 1383863 R catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase complement(1382871..1383863) Helicobacter pylori J99 890401 NP_223984.1 CDS ung NC_000921.1 1383952 1384653 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1383952..1384653) Helicobacter pylori J99 889882 NP_223985.1 CDS plsC NC_000921.1 1384650 1385363 R similar to H. pylori 26695 gene HP1348; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1384650..1385363) Helicobacter pylori J99 889510 NP_223986.1 CDS jhp1268 NC_000921.1 1385350 1386513 R similar to H. pylori 26695 gene HP1349; hypothetical protein complement(1385350..1386513) Helicobacter pylori J99 889859 NP_223987.1 CDS prc NC_000921.1 1386520 1387899 R similar to H. pylori 26695 gene HP1350; carboxyl-terminal protease complement(1386520..1387899) Helicobacter pylori J99 890400 NP_223988.1 CDS jhp1270 NC_000921.1 1388109 1388981 R similar to H. pylori 26695 gene HP1351; hypothetical protein complement(1388109..1388981) Helicobacter pylori J99 889861 NP_223989.1 CDS jhp1271 NC_000921.1 1388981 1390060 R similar to H. pylori 26695 gene HP1352; type II DNA modification (methyltransferase complement(1388981..1390060) Helicobacter pylori J99 890394 NP_223990.1 CDS jhp1272 NC_000921.1 1390189 1393681 R similar to TIGR HP1354; expression of this protein is predicted to be regulated by slipped-strand repair at the two (C) polynucleotide repeats; length of both repeats has been artificially adjusted (addition of one nucleotide in both cases) to give the full length protein; hypothetical protein complement(join(1390189..1390483,1390483..1391310,1391310..1393681)) Helicobacter pylori J99 889862 NP_223991.1 CDS nadC NC_000921.1 1393792 1394613 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1393792..1394613) Helicobacter pylori J99 890391 NP_223992.1 CDS nadA NC_000921.1 1394613 1395623 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(1394613..1395623) Helicobacter pylori J99 889864 NP_223993.1 CDS psd NC_000921.1 1395613 1396416 R catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(1395613..1396416) Helicobacter pylori J99 890390 NP_223994.1 CDS jhp1276 NC_000921.1 1396410 1396916 R similar to H. pylori 26695 gene HP1358; hypothetical protein complement(1396410..1396916) Helicobacter pylori J99 889865 NP_223995.1 CDS jhp1277 NC_000921.1 1396929 1397480 R similar to H. pylori 26695 gene HP1359; hypothetical protein complement(1396929..1397480) Helicobacter pylori J99 890387 NP_223996.1 CDS ubiA NC_000921.1 1397416 1398300 R UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase complement(1397416..1398300) Helicobacter pylori J99 889866 NP_223997.1 CDS comEC NC_000921.1 1398329 1399558 R similar to H. pylori 26695 gene HP1361; DNA transfer protein complement(1398329..1399558) Helicobacter pylori J99 890386 NP_223998.1 CDS dnaB NC_000921.1 1399639 1401099 R unwinds double stranded DNA; replicative DNA helicase complement(1399639..1401099) Helicobacter pylori J99 889867 NP_223999.1 CDS jhp1281 NC_000921.1 1401110 1402504 R similar to H. pylori 26695 gene HP1363; hypothetical protein complement(1401110..1402504) Helicobacter pylori J99 890380 NP_224000.1 CDS jhp1282 NC_000921.1 1402507 1403541 R similar to H. pylori 26695 gene HP1364; histidine kinase sensor protein complement(1402507..1403541) Helicobacter pylori J99 889875 NP_224001.1 CDS jhp1283 NC_000921.1 1403675 1404316 R similar to H. pylori 26695 gene HP1365; transcriptional regulator complement(1403675..1404316) Helicobacter pylori J99 890366 NP_224002.1 CDS jhp1284 NC_000921.1 1404425 1406374 D type II DNA modification (methyltransferase 1404425..1406374 Helicobacter pylori J99 889868 NP_224003.1 CDS jhp1285 NC_000921.1 1406384 1409302 D similar to H. pylori 26695 gene HP1371; type III restriction enzyme R protein 1406384..1409302 Helicobacter pylori J99 890382 NP_224004.1 CDS jhp1286 NC_000921.1 1409352 1410098 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(1409352..1410098) Helicobacter pylori J99 889869 NP_224005.1 CDS mreB NC_000921.1 1410102 1411145 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(1410102..1411145) Helicobacter pylori J99 890379 NP_224006.1 CDS clpX NC_000921.1 1411198 1412556 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1411198..1412556) Helicobacter pylori J99 889870 NP_224007.1 CDS lpxA NC_000921.1 1412558 1413370 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1412558..1413370) Helicobacter pylori J99 890374 NP_224008.1 CDS fabZ NC_000921.1 1413373 1413852 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1413373..1413852) Helicobacter pylori J99 889871 NP_224009.1 CDS jhp1291 NC_000921.1 1414034 1414423 R binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW complement(1414034..1414423) Helicobacter pylori J99 890371 NP_224010.1 CDS jhp1292 NC_000921.1 1414826 1415488 D similar to H. pylori 26695 gene HP1378; hypothetical protein 1414826..1415488 Helicobacter pylori J99 889872 NP_224011.1 CDS lon NC_000921.1 1415531 1418026 D similar to H. pylori 26695 gene HP1379; ATP-dependent protease LA 1415531..1418026 Helicobacter pylori J99 890375 NP_224012.1 CDS tyrA NC_000921.1 1418035 1418862 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1418035..1418862 Helicobacter pylori J99 889873 NP_224013.1 CDS jhp1295 NC_000921.1 1419313 1420176 R similar to H. pylori 26695 gene HP1382; endonuclease complement(1419313..1420176) Helicobacter pylori J99 890373 NP_224014.1 CDS mod_1 NC_000921.1 1420437 1422299 R type III DNA modification enzyme complement(1420437..1422299) Helicobacter pylori J99 889877 NP_224015.1 CDS res_1 NC_000921.1 1422293 1424632 R type III restriction enzyme complement(1422293..1424632) Helicobacter pylori J99 890364 NP_224016.1 CDS bioB NC_000921.1 1425041 1425889 D catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1425041..1425889 Helicobacter pylori J99 889874 NP_224017.1 CDS rbn NC_000921.1 1425889 1426767 D similar to H. pylori 26695 gene HP1407; ribonuclease N 1425889..1426767 Helicobacter pylori J99 890369 NP_224018.1 CDS jhp1300 NC_000921.1 1430913 1431449 D similar to H. pylori 26695 gene HP1408; hypothetical protein 1430913..1431449 Helicobacter pylori J99 889878 NP_224019.1 CDS jhp1301 NC_000921.1 1431394 1432338 D similar to H. pylori 26695 gene HP1409; hypothetical protein 1431394..1432338 Helicobacter pylori J99 890360 NP_224020.1 CDS jhp1302 NC_000921.1 1432520 1433125 D similar to H. pylori 26695 gene HP1409; hypothetical protein 1432520..1433125 Helicobacter pylori J99 889876 NP_224021.1 CDS jhp1303 NC_000921.1 1433171 1434403 D similar to H. pylori 26695 gene HP1410; hypothetical protein 1433171..1434403 Helicobacter pylori J99 890367 NP_224022.1 CDS jhp1304 NC_000921.1 1434471 1435400 D similar to H. pylori 26695 gene HP1411; hypothetical protein 1434471..1435400 Helicobacter pylori J99 889879 NP_224023.1 CDS jhp1305 NC_000921.1 1435587 1436318 D similar to H. pylori 26695 gene HP1411; hypothetical protein 1435587..1436318 Helicobacter pylori J99 890363 NP_224024.1 CDS jhp1306 NC_000921.1 1436452 1436607 D hypothetical protein 1436452..1436607 Helicobacter pylori J99 889880 NP_224025.1 CDS jhp1307 NC_000921.1 1436642 1437364 D similar to H. pylori 26695 gene HP1412; hypothetical protein 1436642..1437364 Helicobacter pylori J99 890361 NP_224026.1 CDS jhp1308 NC_000921.1 1437494 1437940 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(1437494..1437940) Helicobacter pylori J99 889881 NP_224027.1 CDS jhp1309 NC_000921.1 1437999 1438340 D similar to H. pylori 26695 gene HP1414; hypothetical protein 1437999..1438340 Helicobacter pylori J99 889451 NP_224028.1 CDS miaA NC_000921.1 1438411 1439244 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1438411..1439244 Helicobacter pylori J99 889884 NP_224029.1 CDS jhp1311 NC_000921.1 1439245 1440348 D similar to H. pylori 26695 gene HP1416; lipopolysaccharide biosynthesis protein 1439245..1440348 Helicobacter pylori J99 889355 NP_224030.1 CDS jhp1312 NC_000921.1 1440365 1442024 D similar to TIGR HP1417; expression of this protein is predicted to be regulated by slipped-strand repair at the (AG) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein join(1440365..1441149,1441148..1442024) Helicobacter pylori J99 889883 NP_224031.1 CDS murB NC_000921.1 1442085 1442864 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1442085..1442864) Helicobacter pylori J99 889470 NP_224032.1 CDS fliQ NC_000921.1 1442868 1443134 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(1442868..1443134) Helicobacter pylori J99 889895 NP_224033.1 CDS fliI NC_000921.1 1443145 1444449 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(1443145..1444449) Helicobacter pylori J99 889885 NP_224034.1 CDS virB11_2 NC_000921.1 1444450 1445364 R similar to H. pylori 26695 gene HP1421; DNA transfer protein complement(1444450..1445364) Helicobacter pylori J99 889350 NP_224035.1 CDS ileS NC_000921.1 1445381 1448143 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1445381..1448143) Helicobacter pylori J99 889886 NP_224036.1 CDS jhp1318 NC_000921.1 1448163 1448417 R similar to H. pylori 26695 gene HP1423; hypothetical protein complement(1448163..1448417) Helicobacter pylori J99 889404 NP_224037.1 CDS jhp1319 NC_000921.1 1448519 1449139 D similar to H. pylori 26695 gene HP1424; hypothetical protein 1448519..1449139 Helicobacter pylori J99 889887 NP_224038.1 CDS jhp1320 NC_000921.1 1449374 1449556 R similar to H. pylori 26695 gene HP1427; histidine-rich metal-binding protein complement(1449374..1449556) Helicobacter pylori J99 889511 NP_224039.1 CDS jhp1321 NC_000921.1 1449828 1450061 R similar to H. pylori 26695 gene HP1432; histidine and glutamine-rich metal-binding protein complement(1449828..1450061) Helicobacter pylori J99 889890 NP_224040.1 CDS ksgA NC_000921.1 1450314 1451129 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1450314..1451129 Helicobacter pylori J99 889463 NP_224041.1 CDS jhp1323 NC_000921.1 1451180 1453258 D similar to H. pylori 26695 gene HP1430; hypothetical protein 1451180..1453258 Helicobacter pylori J99 889888 NP_224042.1 CDS jhp1324 NC_000921.1 1453242 1454231 D similar to H. pylori 26695 gene HP1429; hypothetical protein 1453242..1454231 Helicobacter pylori J99 889434 NP_224043.1 CDS jhp1325 NC_000921.1 1454228 1455301 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1454228..1455301 Helicobacter pylori J99 889889 NP_224044.1 CDS jhp1326 NC_000921.1 1456084 1458462 R similar to H. pylori 26695 gene HP1433; hypothetical protein complement(1456084..1458462) Helicobacter pylori J99 889421 NP_224045.1 CDS purU NC_000921.1 1458571 1459452 R similar to H. pylori 26695 gene HP1434; formyltetrahydrofolate hydrolase complement(1458571..1459452) Helicobacter pylori J99 889891 NP_224046.1 CDS sppA NC_000921.1 1459455 1460333 R similar to H. pylori 26695 gene HP1435; endopeptidase IV complement(1459455..1460333) Helicobacter pylori J99 889493 NP_224047.1 CDS jhp1329 NC_000921.1 1460404 1460664 D similar to H. pylori 26695 gene HP1436; hypothetical protein 1460404..1460664 Helicobacter pylori J99 889892 NP_224048.1 CDS jhp1330 NC_000921.1 1460871 1461434 D similar to H. pylori 26695 gene HP1437; hypothetical protein 1460871..1461434 Helicobacter pylori J99 889578 NP_224049.1 CDS jhp1331 NC_000921.1 1461570 1462055 D similar to H. pylori 26695 gene HP1438; hypothetical protein 1461570..1462055 Helicobacter pylori J99 889893 NP_224050.1 CDS jhp1332 NC_000921.1 1462065 1462490 D similar to H. pylori 26695 gene HP1439; hypothetical protein 1462065..1462490 Helicobacter pylori J99 889896 NP_224051.1 CDS jhp1333 NC_000921.1 1465043 1465822 R similar to H. pylori 26695 gene HP1440; hypothetical protein complement(1465043..1465822) Helicobacter pylori J99 889900 NP_224052.1 CDS ppiA NC_000921.1 1465946 1466434 D similar to H. pylori 26695 gene HP1441; peptidyl-prolyl cis-trans isomerase 1465946..1466434 Helicobacter pylori J99 889894 NP_224053.1 CDS csrA NC_000921.1 1466452 1466682 D affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1466452..1466682 Helicobacter pylori J99 889897 NP_224054.1 CDS jhp1336 NC_000921.1 1466679 1467503 D catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1466679..1467503 Helicobacter pylori J99 889898 NP_224055.1 CDS smpB NC_000921.1 1467481 1467939 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1467481..1467939 Helicobacter pylori J99 889901 NP_224056.1 CDS exbB_3 NC_000921.1 1467942 1468394 D similar to H. pylori 26695 gene HP1445; biopolymer transport protein 1467942..1468394 Helicobacter pylori J99 889906 NP_224057.1 CDS exbD_3 NC_000921.1 1468405 1468806 D similar to H. pylori 26695 gene HP1446; biopolymer transport protein 1468405..1468806 Helicobacter pylori J99 889899 NP_224058.1 CDS rpmH NC_000921.1 1468878 1469012 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1468878..1469012 Helicobacter pylori J99 889902 NP_224059.1 CDS rnpA NC_000921.1 1468972 1469457 D similar to H. pylori 26695 gene HP1448; ribonuclease P protein component 1468972..1469457 Helicobacter pylori J99 889904 NP_224060.1 CDS jhp1342 NC_000921.1 1469444 1469800 D similar to H. pylori 26695 gene HP1449; hypothetical protein 1469444..1469800 Helicobacter pylori J99 889929 NP_224061.1 CDS jhp1343 NC_000921.1 1469806 1471455 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1469806..1471455 Helicobacter pylori J99 889903 NP_224062.1 CDS jhp1344 NC_000921.1 1471469 1472245 D similar to H. pylori 26695 gene HP1451; hypothetical protein 1471469..1472245 Helicobacter pylori J99 889919 NP_224063.1 CDS trmE NC_000921.1 1472205 1473590 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1472205..1473590 Helicobacter pylori J99 889915 NP_224064.1 CDS jhp1346 NC_000921.1 1473792 1476026 D similar to H. pylori 26695 gene HP1453; hypothetical protein 1473792..1476026 Helicobacter pylori J99 889905 NP_224065.1 CDS jhp1347 NC_000921.1 1476622 1477533 R similar to H. pylori 26695 gene HP1454; hypothetical protein complement(1476622..1477533) Helicobacter pylori J99 889917 NP_224066.1 CDS jhp1348 NC_000921.1 1477543 1477884 R similar to H. pylori 26695 gene HP1455; hypothetical protein complement(1477543..1477884) Helicobacter pylori J99 889909 NP_224067.1 CDS lpp20 NC_000921.1 1477892 1478419 R similar to H. pylori 26695 gene HP1456; lipoprotein complement(1477892..1478419) Helicobacter pylori J99 889907 NP_224068.1 CDS jhp1350 NC_000921.1 1478443 1479075 R similar to H. pylori 26695 gene HP1457; hypothetical protein complement(1478443..1479075) Helicobacter pylori J99 889908 NP_224069.1 CDS jhp1351 NC_000921.1 1479434 1479748 R similar to H. pylori 26695 gene HP1458; thioredoxin complement(1479434..1479748) Helicobacter pylori J99 889911 NP_224070.1 CDS jhp1352 NC_000921.1 1479804 1480592 R similar to H. pylori 26695 gene HP1459; hypothetical protein complement(1479804..1480592) Helicobacter pylori J99 889913 NP_224071.1 CDS dnaE NC_000921.1 1480574 1484209 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1480574..1484209) Helicobacter pylori J99 889910 NP_224072.1 CDS jhp1354 NC_000921.1 1484358 1485410 D similar to H. pylori 26695 gene HP1461; cytochrome c551 peroxidase 1484358..1485410 Helicobacter pylori J99 889912 NP_224073.1 CDS jhp1355 NC_000921.1 1485705 1486292 R similar to H. pylori 26695 gene HP1462; motility protein complement(1485705..1486292) Helicobacter pylori J99 889914 NP_224074.1 CDS jhp1356 NC_000921.1 1486311 1486988 R similar to H. pylori 26695 gene HP1463; hypothetical protein complement(1486311..1486988) Helicobacter pylori J99 889916 NP_224075.1 CDS jhp1357 NC_000921.1 1486991 1487806 R similar to H. pylori 26695 gene HP1464; hypothetical protein complement(1486991..1487806) Helicobacter pylori J99 889932 NP_224076.1 CDS jhp1358 NC_000921.1 1487791 1488576 R similar to H. pylori 26695 gene HP1465; ABC transporter ATP-binding protein complement(1487791..1488576) Helicobacter pylori J99 889506 NP_224077.1 CDS jhp1359 NC_000921.1 1488576 1489709 R similar to H. pylori 26695 gene HP1466; hypothetical protein complement(1488576..1489709) Helicobacter pylori J99 889918 NP_224078.1 CDS jhp1360 NC_000921.1 1489843 1490538 D similar to H. pylori 26695 gene HP1467; hypothetical protein 1489843..1490538 Helicobacter pylori J99 889920 NP_224079.1 CDS ilvE NC_000921.1 1490543 1491565 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1490543..1491565) Helicobacter pylori J99 889921 NP_224080.1 CDS jhp1362 NC_000921.1 1491616 1492362 R similar to H. pylori 26695 gene HP1469; hypothetical protein complement(1491616..1492362) Helicobacter pylori J99 889925 NP_224081.1 CDS polA NC_000921.1 1492476 1495169 R similar to H. pylori 26695 gene HP1470; DNA polymerase I complement(1492476..1495169) Helicobacter pylori J99 889922 NP_224082.1 CDS jhp1364 NC_000921.1 1495233 1496453 R similar to H. pylori 26695 gene HP1471; type II restriction enzyme complement(1495233..1496453) Helicobacter pylori J99 889923 NP_224083.1 CDS jhp1365 NC_000921.1 1496450 1498486 R similar to H. pylori 26695 gene HP1472; type II DNA modification enzyme complement(1496450..1498486) Helicobacter pylori J99 889924 NP_224084.1 CDS jhp1366 NC_000921.1 1498518 1499093 R similar to H. pylori 26695 gene HP1473; hypothetical protein complement(1498518..1499093) Helicobacter pylori J99 889927 NP_224085.1 CDS tmk NC_000921.1 1499081 1499656 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1499081..1499656) Helicobacter pylori J99 889509 NP_224086.1 CDS coaD NC_000921.1 1499660 1500133 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1499660..1500133) Helicobacter pylori J99 889926 NP_224087.1 CDS ubiD NC_000921.1 1500133 1500696 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1500133..1500696) Helicobacter pylori J99 889928 NP_224088.1 CDS flgA NC_000921.1 1500706 1501362 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1500706..1501362) Helicobacter pylori J99 889935 NP_224089.1 CDS rep NC_000921.1 1501359 1503404 R similar to H. pylori 26695 gene HP1478; ATP-dependent DNA helicase complement(1501359..1503404) Helicobacter pylori J99 889497 NP_224090.1 CDS jhp1372 NC_000921.1 1503404 1505929 R similar to H. pylori 26695 gene HP1479; hypothetical protein complement(1503404..1505929) Helicobacter pylori J99 889930 NP_224091.1 CDS serS NC_000921.1 1505939 1507186 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(1505939..1507186) Helicobacter pylori J99 889934 NP_224092.1 CDS jhp1374 NC_000921.1 1507187 1507984 R similar to H. pylori 26695 gene HP1481; hypothetical protein complement(1507187..1507984) Helicobacter pylori J99 889503 NP_224093.1 CDS jhp1375 NC_000921.1 1507988 1508248 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1507988..1508248) Helicobacter pylori J99 889931 NP_224094.1 CDS ubiE NC_000921.1 1508258 1508998 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1508258..1508998) Helicobacter pylori J99 889508 NP_224095.1 CDS jhp1377 NC_000921.1 1509007 1509453 R similar to H. pylori 26695 gene HP1484; hypothetical protein complement(1509007..1509453) Helicobacter pylori J99 889933 NP_224096.1 CDS jhp1378 NC_000921.1 1509463 1510035 R similar to H. pylori 26695 gene HP1485; hypothetical protein complement(1509463..1510035) Helicobacter pylori J99 889504 NP_224097.1 CDS jhp1379 NC_000921.1 1510022 1511152 R similar to H. pylori 26695 gene HP1486; hypothetical protein complement(1510022..1511152) Helicobacter pylori J99 889963 NP_224098.1 CDS jhp1380 NC_000921.1 1511149 1512246 R similar to H. pylori 26695 gene HP1487; hypothetical protein complement(1511149..1512246) Helicobacter pylori J99 889454 NP_224099.1 CDS jhp1381 NC_000921.1 1512258 1513247 R similar to H. pylori 26695 gene HP1488; hypothetical protein complement(1512258..1513247) Helicobacter pylori J99 889936 NP_224100.1 CDS jhp1382 NC_000921.1 1513259 1514791 R similar to H. pylori 26695 gene HP1489; lipase-like protein complement(1513259..1514791) Helicobacter pylori J99 889501 NP_224101.1 CDS jhp1383 NC_000921.1 1514788 1516113 R similar to H. pylori 26695 gene HP1490; hypothetical protein complement(1514788..1516113) Helicobacter pylori J99 889937 NP_224102.1 CDS jhp1384 NC_000921.1 1516243 1517844 R similar to H. pylori 26695 gene HP1491; phosphate permease complement(1516243..1517844) Helicobacter pylori J99 889498 NP_224103.1 CDS jhp1385 NC_000921.1 1517985 1518254 D similar to H. pylori 26695 gene HP1492; NifU-like protein 1517985..1518254 Helicobacter pylori J99 889941 NP_224104.1 CDS jhp1386 NC_000921.1 1518267 1518878 D similar to H. pylori 26695 gene HP1493; hypothetical protein 1518267..1518878 Helicobacter pylori J99 889496 NP_224105.1 CDS murE NC_000921.1 1518882 1520225 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1518882..1520225 Helicobacter pylori J99 889938 NP_224106.1 CDS tal NC_000921.1 1520228 1521178 D Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1520228..1521178 Helicobacter pylori J99 889492 NP_224107.1 CDS rplY NC_000921.1 1521233 1521769 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1521233..1521769 Helicobacter pylori J99 889939 NP_224108.1 CDS pth NC_000921.1 1521779 1522339 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1521779..1522339 Helicobacter pylori J99 889488 NP_224109.1 CDS jhp1391 NC_000921.1 1522349 1523416 D similar to H. pylori 26695 gene HP1498; hypothetical protein 1522349..1523416 Helicobacter pylori J99 889940 NP_224110.1 CDS jhp1392 NC_000921.1 1523537 1524457 D similar to H. pylori 26695 gene HP1499; hypothetical protein 1523537..1524457 Helicobacter pylori J99 889495 NP_224111.1 CDS jhp1393 NC_000921.1 1524624 1524704 D similar to H. pylori 26695 gene HP1500; hypothetical protein 1524624..1524704 Helicobacter pylori J99 889942 NP_224112.1 CDS jhp1394 NC_000921.1 1524768 1525934 R similar to H. pylori 26695 gene HP1501; hypothetical protein complement(1524768..1525934) Helicobacter pylori J99 889491 NP_224113.1 CDS jhp1395 NC_000921.1 1526113 1526550 D similar to H. pylori 26695 gene HP1502; hypothetical protein 1526113..1526550 Helicobacter pylori J99 889943 NP_224114.1 CDS fixI NC_000921.1 1526547 1528913 R similar to H. pylori 26695 gene HP1503; component of cation transport for cbb3-type oxidase complement(1526547..1528913) Helicobacter pylori J99 889482 NP_224115.1 CDS jhp1397 NC_000921.1 1528923 1529639 R similar to H. pylori 26695 gene HP1504; hypothetical protein complement(1528923..1529639) Helicobacter pylori J99 889946 NP_224116.1 CDS ribD NC_000921.1 1529621 1530655 R similar to H. pylori 26695 gene HP1505; riboflavin-specific deaminase complement(1529621..1530655) Helicobacter pylori J99 889484 NP_224117.1 CDS gltS NC_000921.1 1530659 1531885 R similar to H. pylori 26695 gene HP1506; sodium/glutamate symporter complement(1530659..1531885) Helicobacter pylori J99 889944 NP_224118.1 CDS jhp1400 NC_000921.1 1531971 1533170 D similar to H. pylori 26695 gene HP1507; hypothetical protein 1531971..1533170 Helicobacter pylori J99 889483 NP_224119.1 CDS jhp1401 NC_000921.1 1533180 1534556 R similar to H. pylori 26695 gene HP1508; ferrodoxin complement(1533180..1534556) Helicobacter pylori J99 889945 NP_224120.1 CDS jhp1402 NC_000921.1 1534662 1535324 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1534662..1535324 Helicobacter pylori J99 889486 NP_224121.1 CDS folB NC_000921.1 1535321 1535674 D similar to H. pylori 26695 gene HP1510; dihydroneopterin aldolase 1535321..1535674 Helicobacter pylori J99 889949 NP_224122.1 CDS jhp1404 NC_000921.1 1535658 1535984 D similar to H. pylori 26695 gene HP1511; hypothetical protein 1535658..1535984 Helicobacter pylori J99 889477 NP_224123.1 CDS frpB_3 NC_000921.1 1536153 1538792 D similar to H. pylori 26695 gene HP1512; IRON-regulated outer membrane protein 1536153..1538792 Helicobacter pylori J99 889947 NP_224124.1 CDS selA NC_000921.1 1539018 1540190 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1539018..1540190 Helicobacter pylori J99 889478 NP_224125.1 CDS nusA NC_000921.1 1540286 1541473 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1540286..1541473 Helicobacter pylori J99 889948 NP_224126.1 CDS jhp1408 NC_000921.1 1541530 1542213 D hypothetical protein 1541530..1542213 Helicobacter pylori J99 889479 NP_224127.1 CDS jhp1409 NC_000921.1 1543496 1547254 R type II DNA modification enzyme complement(1543496..1547254) Helicobacter pylori J99 889951 NP_224128.1 CDS res_2 NC_000921.1 1547376 1550285 R similar to H. pylori 26695 gene HP1521; type III restriction enzyme complement(1547376..1550285) Helicobacter pylori J99 889471 NP_224129.1 CDS mod_2 NC_000921.1 1550288 1552214 R similar to TIGR HP1522; expression of this protein is predicted to be regulated by slipped-strand repair at the (G) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; type III DNA modification enzyme complement(join(1550288..1550881,1550883..1552214)) Helicobacter pylori J99 889950 NP_224130.1 CDS recG NC_000921.1 1552266 1554137 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1552266..1554137) Helicobacter pylori J99 889476 NP_224131.1 CDS jhp1413 NC_000921.1 1554214 1554561 D similar to H. pylori 26695 gene HP1524; hypothetical protein 1554214..1554561 Helicobacter pylori J99 889955 NP_224132.1 CDS jhp1414 NC_000921.1 1554565 1555200 D similar to H. pylori 26695 gene HP1525; hypothetical protein 1554565..1555200 Helicobacter pylori J99 889468 NP_224133.1 CDS exoA NC_000921.1 1555197 1555949 R AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III complement(1555197..1555949) Helicobacter pylori J99 889953 NP_224134.1 CDS jhp1416 NC_000921.1 1556129 1557568 R similar to H. pylori 26695 gene HP1527; hypothetical protein complement(1556129..1557568) Helicobacter pylori J99 889472 NP_224135.1 CDS dnaA NC_000921.1 1557789 1559162 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA complement(1557789..1559162) Helicobacter pylori J99 889952 NP_224136.1 CDS jhp1418 NC_000921.1 1559315 1559857 D similar to H. pylori 26695 gene HP1530; hypothetical protein 1559315..1559857 Helicobacter pylori J99 889473 NP_224137.1 CDS jhp1419 NC_000921.1 1559902 1560141 D similar to H. pylori 26695 gene HP1531; hypothetical protein 1559902..1560141 Helicobacter pylori J99 889954 NP_224138.1 CDS glmS NC_000921.1 1560142 1561935 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1560142..1561935 Helicobacter pylori J99 889462 NP_224139.1 CDS thyX NC_000921.1 1561959 1562585 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1561959..1562585 Helicobacter pylori J99 889956 NP_224140.1 CDS hsdS_3a NC_000921.1 1562916 1564790 R type I restriction enzyme (specificity subunit) complement(1562916..1564790) Helicobacter pylori J99 889469 NP_224141.1 CDS hsdM_3 NC_000921.1 1564787 1567234 R similar to H. pylori 26695 gene HP1403; type I restriction enzyme modification subunit complement(1564787..1567234) Helicobacter pylori J99 889239 NP_224142.1 CDS hsdR_3 NC_000921.1 1567305 1570280 D similar to H. pylori 26695 gene HP1402; type I restriction enzyme restriction subunit 1567305..1570280 Helicobacter pylori J99 889957 NP_224143.1 CDS jhp1425 NC_000921.1 1570280 1570987 D similar to H. pylori 26695 gene HP1401; hypothetical protein 1570280..1570987 Helicobacter pylori J99 889458 NP_224144.1 CDS fecA_3 NC_000921.1 1571081 1573606 R similar to H. pylori 26695 gene HP1400; IRON(III) dicitrate transport protein complement(1571081..1573606) Helicobacter pylori J99 889958 NP_224145.1 CDS rocF NC_000921.1 1574136 1575104 R similar to H. pylori 26695 gene HP1399; arginase complement(1574136..1575104) Helicobacter pylori J99 889313 NP_224146.1 CDS ald NC_000921.1 1575308 1576450 D similar to H. pylori 26695 gene HP1398; L-alanine dehydrogenase 1575308..1576450 Helicobacter pylori J99 889959 NP_224147.1 CDS jhp1429 NC_000921.1 1576698 1577795 D zinc-dependent alcohol dehydrogenase 1576698..1577795 Helicobacter pylori J99 889443 NP_224148.1 CDS jhp1430 NC_000921.1 1577928 1578776 D similar to H. pylori 26695 gene HP1397; hypothetical protein 1577928..1578776 Helicobacter pylori J99 889960 NP_224149.1 CDS jhp1431 NC_000921.1 1578809 1579690 D similar to H. pylori 26695 gene HP1396; hypothetical protein 1578809..1579690 Helicobacter pylori J99 889461 NP_224150.1 CDS jhp1432 NC_000921.1 1579701 1580429 R similar to H. pylori 26695 gene HP1395; hypothetical protein complement(1579701..1580429) Helicobacter pylori J99 889961 NP_224151.1 CDS jhp1433 NC_000921.1 1580545 1581468 D similar to H. pylori 26695 gene HP1394; hypothetical protein 1580545..1581468 Helicobacter pylori J99 889455 NP_224152.1 CDS recN NC_000921.1 1581506 1583074 D similar to H. pylori 26695 gene HP1393; DNA repair protein(recombination protein N) 1581506..1583074 Helicobacter pylori J99 889967 NP_224153.1 CDS jhp1435 NC_000921.1 1583077 1584384 D similar to H. pylori 26695 gene HP1392; fibronectin/fibrinogen-binding protein 1583077..1584384 Helicobacter pylori J99 889448 NP_224154.1 CDS jhp1436 NC_000921.1 1584403 1584699 D similar to H. pylori 26695 gene HP1391; hypothetical protein 1584403..1584699 Helicobacter pylori J99 889964 NP_224155.1 CDS jhp1437 NC_000921.1 1584853 1585623 D hypothetical protein 1584853..1585623 Helicobacter pylori J99 889449 NP_224156.1 CDS jhp1438 NC_000921.1 1585662 1586633 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1585662..1586633) Helicobacter pylori J99 889962 NP_224157.1 CDS rpe NC_000921.1 1586503 1587156 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1586503..1587156) Helicobacter pylori J99 889965 NP_224158.1 CDS fbp NC_000921.1 1587227 1588099 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1587227..1588099 Helicobacter pylori J99 889456 NP_224159.1 CDS jhp1441 NC_000921.1 1588099 1588302 D similar to H. pylori 26695 gene HP1384; hypothetical protein 1588099..1588302 Helicobacter pylori J99 889972 NP_224160.1 CDS jhp1442 NC_000921.1 1588369 1589350 D similar to TIGR HP1366; expression of this protein is predicted to be regulated by slipped-strand repair at the (A) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; type II restriction enzyme join(1588369..1589034,1589036..1589350) Helicobacter pylori J99 889439 NP_224161.1 CDS jhp1443 NC_000921.1 1589437 1590078 D similar to H. pylori 26695 gene HP1365; transcriptional regulator 1589437..1590078 Helicobacter pylori J99 889966 NP_224162.1 CDS tsf NC_000921.1 1590257 1591324 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1590257..1591324) Helicobacter pylori J99 889447 NP_224163.1 CDS rpsB NC_000921.1 1591324 1592118 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1591324..1592118) Helicobacter pylori J99 889970 NP_224164.1 CDS pcrA NC_000921.1 1592367 1595207 D similar to H. pylori 26695 gene HP1553; recombination protein RecB 1592367..1595207 Helicobacter pylori J99 889442 NP_224165.1 CDS nhaA NC_000921.1 1595231 1596547 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1595231..1596547 Helicobacter pylori J99 889971 NP_224166.1 CDS yajC NC_000921.1 1596595 1596888 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1596595..1596888 Helicobacter pylori J99 889440 NP_224167.1 CDS secD NC_000921.1 1596889 1598469 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1596889..1598469 Helicobacter pylori J99 889286 NP_224168.1 CDS secF NC_000921.1 1598478 1599449 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1598478..1599449 Helicobacter pylori J99 889968 NP_224169.1 CDS jhp1451 NC_000921.1 1599459 1599797 D similar to H. pylori 26695 gene HP1548; hypothetical protein 1599459..1599797 Helicobacter pylori J99 889450 NP_224170.1 CDS leuS NC_000921.1 1599807 1602227 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1599807..1602227 Helicobacter pylori J99 889287 NP_224171.1 CDS jhp1453 NC_000921.1 1602224 1602736 D similar to H. pylori 26695 gene HP1546; hypothetical protein 1602224..1602736 Helicobacter pylori J99 889976 NP_224172.1 CDS folC NC_000921.1 1602726 1603895 D similar to H. pylori 26695 gene HP1545; folylpolyglutamate synthase 1602726..1603895 Helicobacter pylori J99 889430 NP_224173.1 CDS jhp1455 NC_000921.1 1603895 1604821 D similar to H. pylori 26695 gene HP1544; hypothetical protein 1603895..1604821 Helicobacter pylori J99 889969 NP_224174.1 CDS jhp1456 NC_000921.1 1604831 1605769 D similar to H. pylori 26695 gene HP1543; hypothetical protein 1604831..1605769 Helicobacter pylori J99 889444 NP_224175.1 CDS jhp1457 NC_000921.1 1605688 1606098 D similar to H. pylori 26695 gene HP1542; hypothetical protein 1605688..1606098 Helicobacter pylori J99 889975 NP_224176.1 CDS mfd NC_000921.1 1606102 1609107 D similar to H. pylori 26695 gene HP1541; transcription-repair coupling factor 1606102..1609107 Helicobacter pylori J99 889438 NP_224177.1 CDS petA NC_000921.1 1609232 1609735 D similar to H. pylori 26695 gene HP1540; ubiquinol cytochrome c oxidoreductase, 2Fe-2S subunit 1609232..1609735 Helicobacter pylori J99 889978 NP_224178.1 CDS petB NC_000921.1 1609746 1610984 D similar to H. pylori 26695 gene HP1539; ubiquinol cytochrome c oxidoreductase, cytochrome b subunit 1609746..1610984 Helicobacter pylori J99 889433 NP_224179.1 CDS petC NC_000921.1 1610981 1611838 D similar to H. pylori 26695 gene HP1538; ubiquinol cytochrome c oxidoreductase, cytochrome c1 1610981..1611838 Helicobacter pylori J99 889977 NP_224180.1 CDS jhp1462 NC_000921.1 1612166 1612696 R hypothetical protein complement(1612166..1612696) Helicobacter pylori J99 889435 NP_224181.1 CDS jhp1463 NC_000921.1 1612696 1613799 R hypothetical protein complement(1612696..1613799) Helicobacter pylori J99 889981 NP_224182.1 CDS jhp1464 NC_000921.1 1614129 1615970 R similar to H. pylori 26695 gene HP1556; penicillin-binding protein complement(1614129..1615970) Helicobacter pylori J99 889973 NP_224183.1 CDS fliE NC_000921.1 1616126 1616455 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1616126..1616455) Helicobacter pylori J99 889299 NP_224184.1 CDS flgC NC_000921.1 1616583 1617068 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(1616583..1617068) Helicobacter pylori J99 889992 NP_224185.1 CDS flgB NC_000921.1 1617081 1617503 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB complement(1617081..1617503) Helicobacter pylori J99 889409 NP_224186.1 CDS rodA_2 NC_000921.1 1617708 1618874 D similar to H. pylori 26695 gene HP1560; rod shape-determining protein 1617708..1618874 Helicobacter pylori J99 889974 NP_224187.1 CDS jhp1469 NC_000921.1 1618897 1619904 R similar to H. pylori 26695 gene HP1561; hypothetical protein complement(1618897..1619904) Helicobacter pylori J99 889441 NP_224188.1 CDS jhp1470 NC_000921.1 1620112 1621113 R similar to H. pylori 26695 gene HP1562; hypothetical protein complement(1620112..1621113) Helicobacter pylori J99 889979 NP_224189.1 CDS tsaA NC_000921.1 1621351 1621947 D similar to H. pylori 26695 gene HP1563; peroxidase 1621351..1621947 Helicobacter pylori J99 889432 NP_224190.1 CDS jhp1472 NC_000921.1 1622093 1622908 D similar to H. pylori 26695 gene HP1564; hypothetical protein 1622093..1622908 Helicobacter pylori J99 889980 NP_224191.1 CDS jhp1473 NC_000921.1 1623355 1625121 R similar to H. pylori 26695 gene HP1565; penicillin-binding protein complement(1623355..1625121) Helicobacter pylori J99 889423 NP_224192.1 CDS jhp1474 NC_000921.1 1625102 1625545 R similar to H. pylori 26695 gene HP1566; hypothetical protein complement(1625102..1625545) Helicobacter pylori J99 889983 NP_224193.1 CDS engB NC_000921.1 1625555 1626181 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1625555..1626181) Helicobacter pylori J99 889428 NP_224194.1 CDS jhp1476 NC_000921.1 1626178 1626735 R similar to H. pylori 26695 gene HP1568; hypothetical protein complement(1626178..1626735) Helicobacter pylori J99 888969 NP_224195.1 CDS jhp1477 NC_000921.1 1626735 1627328 R similar to H. pylori 26695 gene HP1569; hypothetical protein complement(1626735..1627328) Helicobacter pylori J99 889331 NP_224196.1 CDS jhp1478 NC_000921.1 1627303 1627797 R similar to H. pylori 26695 gene HP1570; hypothetical protein complement(1627303..1627797) Helicobacter pylori J99 889242 NP_224197.1 CDS jhp1479 NC_000921.1 1627794 1628738 R similar to H. pylori 26695 gene HP1571; hypothetical protein complement(1627794..1628738) Helicobacter pylori J99 889303 NP_224198.1 CDS dniR NC_000921.1 1628738 1629862 R similar to H. pylori 26695 gene HP1572; regulatory protein DniR complement(1628738..1629862) Helicobacter pylori J99 889341 NP_224199.1 CDS jhp1481 NC_000921.1 1629946 1630710 R similar to H. pylori 26695 gene HP1573; hypothetical protein complement(1629946..1630710) Helicobacter pylori J99 889362 NP_224200.1 CDS ribC NC_000921.1 1630785 1631405 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1630785..1631405 Helicobacter pylori J99 888985 NP_224201.1 CDS flhB_2 NC_000921.1 1631406 1631678 D similar to H. pylori 26695 gene HP1575; flagellar biosynthesis protein 1631406..1631678 Helicobacter pylori J99 889278 NP_224202.1 CDS metN NC_000921.1 1631697 1632680 D part of the metNIQ transport system for methionine; methionine ABC transporter ATP-binding protein 1631697..1632680 Helicobacter pylori J99 889222 NP_224203.1 CDS jhp1485 NC_000921.1 1632682 1633329 D similar to H. pylori 26695 gene HP1577; ABC transporter permease 1632682..1633329 Helicobacter pylori J99 888989 NP_224204.1 CDS jhp1486 NC_000921.1 1633520 1633942 R similar to H. pylori 26695 gene HP1579; hypothetical protein complement(1633520..1633942) Helicobacter pylori J99 889010 NP_224205.1 CDS jhp1487 NC_000921.1 1633952 1634548 R similar to H. pylori 26695 gene HP1580; hypothetical protein complement(1633952..1634548) Helicobacter pylori J99 889279 NP_224206.1 CDS wecA NC_000921.1 1634548 1635555 R similar to H. pylori 26695 gene HP1581; undecaprenyl-phosphate-alpha-N- acetylglucosaminyltransferase complement(1634548..1635555) Helicobacter pylori J99 889007 NP_224207.1 CDS pdxJ NC_000921.1 1635691 1636479 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1635691..1636479 Helicobacter pylori J99 889349 NP_224208.1 CDS pdxA NC_000921.1 1636481 1637404 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1636481..1637404 Helicobacter pylori J99 889008 NP_224209.1 CDS ydiE NC_000921.1 1637754 1638776 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1637754..1638776 Helicobacter pylori J99 889023 NP_224210.1 CDS flgG NC_000921.1 1639654 1640442 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1639654..1640442 Helicobacter pylori J99 888991 NP_224211.1 CDS jhp1493 NC_000921.1 1640766 1641395 R similar to H. pylori 26695 gene HP1587; hypothetical protein complement(1640766..1641395) Helicobacter pylori J99 889364 NP_224212.1 CDS jhp1494 NC_000921.1 1642226 1642987 R similar to H. pylori 26695 gene HP1588; hypothetical protein complement(1642226..1642987) Helicobacter pylori J99 889343 NP_224213.1 CDS jhp1495 NC_000921.1 1643353 1643586 R hypothetical protein complement(1643353..1643586) Helicobacter pylori J99 889347 jhp_t01 tRNA jhp_t01 NC_000921.1 4079 4154 R tRNA-Glu complement(4079..4154) Helicobacter pylori J99 5183259 jhp_t02 tRNA jhp_t02 NC_000921.1 4214 4290 R tRNA-Asp complement(4214..4290) Helicobacter pylori J99 5183265 jhp_t03 tRNA jhp_t03 NC_000921.1 4341 4416 R tRNA-Val complement(4341..4416) Helicobacter pylori J99 5183266 jhp_t04 tRNA jhp_t04 NC_000921.1 4454 4528 R tRNA-Glu complement(4454..4528) Helicobacter pylori J99 5183267 jhp_t05 tRNA jhp_t05 NC_000921.1 4541 4616 R tRNA-Lys complement(4541..4616) Helicobacter pylori J99 5183269 jhp_t06 tRNA jhp_t06 NC_000921.1 75728 75803 R tRNA-Val complement(75728..75803) Helicobacter pylori J99 5183264 jhp_t07 tRNA jhp_t07 NC_000921.1 93161 93252 D tRNA-Ser 93161..93252 Helicobacter pylori J99 5183262 jhp_t08 tRNA jhp_t08 NC_000921.1 235335 235409 R tRNA-Asn complement(235335..235409) Helicobacter pylori J99 5183248 jhp_t09 tRNA jhp_t09 NC_000921.1 258389 258464 R tRNA-Ala complement(258389..258464) Helicobacter pylori J99 5183251 jhp_t10 tRNA jhp_t10 NC_000921.1 341122 341198 D tRNA-Arg 341122..341198 Helicobacter pylori J99 5183272 jhp_t11 tRNA jhp_t11 NC_000921.1 391010 391097 R tRNA-Ser complement(391010..391097) Helicobacter pylori J99 5183275 jhp_t12 tRNA jhp_t12 NC_000921.1 442334 442411 R tRNA-Pro complement(442334..442411) Helicobacter pylori J99 5183268 jhp_t13 tRNA jhp_t13 NC_000921.1 760036 760112 R tRNA-Met complement(760036..760112) Helicobacter pylori J99 5183257 jhp_t14 tRNA jhp_t14 NC_000921.1 852570 852646 D tRNA-Arg 852570..852646 Helicobacter pylori J99 5183263 jhp_t15 tRNA jhp_t15 NC_000921.1 915399 915475 R tRNA-Met complement(915399..915475) Helicobacter pylori J99 5183246 jhp_t16 tRNA jhp_t16 NC_000921.1 915508 915582 R tRNA-Gln complement(915508..915582) Helicobacter pylori J99 5183252 jhp_t17 tRNA jhp_t17 NC_000921.1 974561 974636 D tRNA-Gly 974561..974636 Helicobacter pylori J99 5183273 jhp_t18 tRNA jhp_t18 NC_000921.1 974676 974762 D tRNA-Leu 974676..974762 Helicobacter pylori J99 5183271 jhp_t19 tRNA jhp_t19 NC_000921.1 974816 974890 D tRNA-Cys 974816..974890 Helicobacter pylori J99 5183260 jhp_t20 tRNA jhp_t20 NC_000921.1 974940 975027 D tRNA-Ser 974940..975027 Helicobacter pylori J99 5183261 jhp_t21 tRNA jhp_t21 NC_000921.1 1076698 1076774 R tRNA-Arg complement(1076698..1076774) Helicobacter pylori J99 5183278 jhp_t22 tRNA jhp_t22 NC_000921.1 1076796 1076872 R tRNA-Arg complement(1076796..1076872) Helicobacter pylori J99 5183250 jhp_t23 tRNA jhp_t23 NC_000921.1 1076932 1077008 R tRNA-His complement(1076932..1077008) Helicobacter pylori J99 5183254 jhp_t24 tRNA jhp_t24 NC_000921.1 1077075 1077152 R tRNA-Pro complement(1077075..1077152) Helicobacter pylori J99 5183255 jhp_t25 tRNA jhp_t25 NC_000921.1 1127524 1127608 R tRNA-Leu complement(1127524..1127608) Helicobacter pylori J99 5183258 jhp_t26 tRNA jhp_t26 NC_000921.1 1132400 1132476 D tRNA-Ile 1132400..1132476 Helicobacter pylori J99 5183253 jhp_t27 tRNA jhp_t27 NC_000921.1 1132494 1132569 D tRNA-Ala 1132494..1132569 Helicobacter pylori J99 5183247 jhp_t28 tRNA jhp_t28 NC_000921.1 1230231 1230308 R tRNA-Met complement(1230231..1230308) Helicobacter pylori J99 5183270 jhp_t29 tRNA jhp_t29 NC_000921.1 1258703 1258778 R tRNA-Trp complement(1258703..1258778) Helicobacter pylori J99 5183249 jhp_t30 tRNA jhp_t30 NC_000921.1 1260350 1260424 R tRNA-Thr complement(1260350..1260424) Helicobacter pylori J99 5183274 jhp_t31 tRNA jhp_t31 NC_000921.1 1260455 1260531 R tRNA-Gly complement(1260455..1260531) Helicobacter pylori J99 5183243 jhp_t32 tRNA jhp_t32 NC_000921.1 1260548 1260632 R tRNA-Tyr complement(1260548..1260632) Helicobacter pylori J99 5183244 jhp_t33 tRNA jhp_t33 NC_000921.1 1260660 1260735 R tRNA-Thr complement(1260660..1260735) Helicobacter pylori J99 5183276 jhp_t34 tRNA jhp_t34 NC_000921.1 1266069 1266155 R tRNA-Leu complement(1266069..1266155) Helicobacter pylori J99 5183277 jhp_t35 tRNA jhp_t35 NC_000921.1 1266209 1266295 R tRNA-Leu complement(1266209..1266295) Helicobacter pylori J99 5183256 jhp_t36 tRNA jhp_t36 NC_000921.1 1556051 1556126 D tRNA-Phe 1556051..1556126 Helicobacter pylori J99 5183245 jhpr1 rRNA jhpr1 NC_000921.1 1057194 1057327 R 5S ribosomal RNA complement(1057194..1057327) Helicobacter pylori J99 4794246 jhpr2 rRNA jhpr2 NC_000921.1 1057558 1060441 R 23S ribosomal RNA complement(1057558..1060441) Helicobacter pylori J99 4794247 jhpr3 rRNA jhpr3 NC_000921.1 1188029 1189529 R 16S ribosomal RNA complement(1188029..1189529) Helicobacter pylori J99 4794248 jhpr4 rRNA jhpr4 NC_000921.1 1427032 1427165 R 5S ribosomal RNA complement(1427032..1427165) Helicobacter pylori J99 4794243 jhpr5 rRNA jhpr5 NC_000921.1 1427396 1430279 R 23S ribosomal RNA complement(1427396..1430279) Helicobacter pylori J99 4794244 jhpr6 rRNA jhpr6 NC_000921.1 1463047 1464547 R 16S ribosomal RNA complement(1463047..1464547) Helicobacter pylori J99 4794245