-- dump date 20140619_113538 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_222723.1 15611072 889080 complement(51..467) 1 NC_000921.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 467 nusB 889080 nusB Helicobacter pylori J99 transcription antitermination protein NusB NP_222723.1 51 R 85963 CDS NP_222724.1 15611073 888968 complement(469..939) 1 NC_000921.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 939 ribH 888968 ribH Helicobacter pylori J99 6,7-dimethyl-8-ribityllumazine synthase NP_222724.1 469 R 85963 CDS NP_222725.1 15611074 889344 complement(949..1779) 1 NC_000921.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1779 kdsA 889344 kdsA Helicobacter pylori J99 2-dehydro-3-deoxyphosphooctonate aldolase NP_222725.1 949 R 85963 CDS NP_222726.1 15611075 889283 complement(1766..2431) 1 NC_000921.1 similar to H. pylori 26695 gene HP0004; carbonic anhydrase 2431 icfA 889283 icfA Helicobacter pylori J99 carbonic anhydrase NP_222726.1 1766 R 85963 CDS NP_222727.1 15611076 889292 2552..3235 1 NC_000921.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 3235 pyrF 889292 pyrF Helicobacter pylori J99 orotidine 5'-phosphate decarboxylase NP_222727.1 2552 D 85963 CDS NP_222728.1 15611077 889294 3235..4065 1 NC_000921.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 4065 panC 889294 panC Helicobacter pylori J99 pantoate--beta-alanine ligase NP_222728.1 3235 D 85963 CDS NP_222729.1 15611078 889297 complement(join(5436..7413,7415..7443)) 1 NC_000921.1 similar to TIGR HP0009; expression of this protein is predicted to be regulated by slipped-strand repair at the (CT) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein 7443 889297 jhp0007 Helicobacter pylori J99 hypothetical protein NP_222729.1 5436 R 85963 CDS NP_222730.1 15611079 889244 complement(7758..9398) 1 NC_000921.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 9398 groEL 889244 groEL Helicobacter pylori J99 molecular chaperone GroEL NP_222730.1 7758 R 85963 CDS NP_222731.1 15611080 889260 complement(9423..9779) 1 NC_000921.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 9779 groES 889260 groES Helicobacter pylori J99 co-chaperonin GroES NP_222731.1 9423 R 85963 CDS NP_222732.1 15611081 889025 10067..11746 1 NC_000921.1 synthesizes RNA primers at the replication forks; DNA primase 11746 dnaG 889025 dnaG Helicobacter pylori J99 DNA primase NP_222732.1 10067 D 85963 CDS NP_222733.1 15611082 889084 11743..12795 1 NC_000921.1 similar to H. pylori 26695 gene HP0013; hypothetical protein 12795 889084 jhp0011 Helicobacter pylori J99 hypothetical protein NP_222733.1 11743 D 85963 CDS NP_222734.1 15611083 889033 12885..13712 1 NC_000921.1 similar to H. pylori 26695 gene HP0014; hypothetical protein 13712 889033 jhp0012 Helicobacter pylori J99 hypothetical protein NP_222734.1 12885 D 85963 CDS NP_222735.1 15611084 889209 13859..14140 1 NC_000921.1 similar to H. pylori 26695 gene HP0015; hypothetical protein 14140 889209 jhp0013 Helicobacter pylori J99 hypothetical protein NP_222735.1 13859 D 85963 CDS NP_222736.1 15611085 889227 14140..14403 1 NC_000921.1 similar to H. pylori 26695 gene HP0016; hypothetical protein 14403 889227 jhp0014 Helicobacter pylori J99 hypothetical protein NP_222736.1 14140 D 85963 CDS NP_222737.1 15611086 889231 14405..16768 1 NC_000921.1 similar to H. pylori 26695 gene HP0017; DNA transfer protein 16768 virB4_1 889231 virB4_1 Helicobacter pylori J99 DNA transfer protein NP_222737.1 14405 D 85963 CDS NP_222738.1 15611087 889054 17008..18417 1 NC_000921.1 similar to H. pylori 26695 gene HP0018; hypothetical protein 18417 889054 jhp0016 Helicobacter pylori J99 hypothetical protein NP_222738.1 17008 D 85963 CDS NP_222739.1 15611088 889258 18524..19489 1 NC_000921.1 similar to H. pylori 26695 gene HP0019; chemotaxis protein 19489 cheV_1 889258 cheV_1 Helicobacter pylori J99 chemotaxis protein NP_222739.1 18524 D 85963 CDS NP_222740.1 15611089 889151 19486..20703 1 NC_000921.1 similar to H. pylori 26695 gene HP0020; carboxynorspermidine decarboxylase 20703 nspC 889151 nspC Helicobacter pylori J99 carboxynorspermidine decarboxylase NP_222740.1 19486 D 85963 CDS NP_222741.1 15611090 889105 complement(20764..21339) 1 NC_000921.1 inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase 21339 889105 jhp0019 Helicobacter pylori J99 lipid A 1-phosphatase NP_222741.1 20764 R 85963 CDS NP_222742.1 15611091 889071 complement(21350..22921) 1 NC_000921.1 attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase 22921 889071 jhp0020 Helicobacter pylori J99 lipid A phosphoethanolamine transferase NP_222742.1 21350 R 85963 CDS NP_222743.1 15611092 889066 complement(23538..25610) 1 NC_000921.1 similar to H. pylori 26695 gene HP0025; hypothetical protein 25610 889066 jhp0021 Helicobacter pylori J99 hypothetical protein NP_222743.1 23538 R 85963 CDS NP_222744.1 15611093 889056 complement(26315..27595) 1 NC_000921.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 27595 gltA 889056 gltA Helicobacter pylori J99 type II citrate synthase NP_222744.1 26315 R 85963 CDS NP_222745.1 15611094 889267 27796..29073 1 NC_000921.1 similar to H. pylori 26695 gene HP0027; isocitrate dehydrogenase 29073 icd 889267 icd Helicobacter pylori J99 isocitrate dehydrogenase NP_222745.1 27796 D 85963 CDS NP_222746.1 15611095 889075 29138..29665 1 NC_000921.1 similar to H. pylori 26695 gene HP0028; hypothetical protein 29665 889075 jhp0024 Helicobacter pylori J99 hypothetical protein NP_222746.1 29138 D 85963 CDS NP_222747.1 15611096 889076 complement(29642..30298) 1 NC_000921.1 similar to H. pylori 26695 gene HP0029; dethiobiotin synthetase 30298 bioD 889076 bioD Helicobacter pylori J99 dethiobiotin synthetase NP_222747.1 29642 R 85963 CDS NP_222748.1 15611097 888999 complement(30302..31999) 1 NC_000921.1 similar to H. pylori 26695 gene HP0030; hypothetical protein 31999 888999 jhp0026 Helicobacter pylori J99 hypothetical protein NP_222748.1 30302 R 85963 CDS NP_222749.1 15611098 889139 32111..32524 1 NC_000921.1 similar to H. pylori 26695 gene HP0031; hypothetical protein 32524 889139 jhp0027 Helicobacter pylori J99 hypothetical protein NP_222749.1 32111 D 85963 CDS NP_222750.1 15611099 889155 32526..32798 1 NC_000921.1 similar to H. pylori 26695 gene HP0032; hypothetical protein 32798 889155 jhp0028 Helicobacter pylori J99 hypothetical protein NP_222750.1 32526 D 85963 CDS NP_222751.1 15611100 889269 32798..35026 1 NC_000921.1 similar to H. pylori 26695 gene HP0033; ATP-dependent protease ATP-binding protein 35026 clpA 889269 clpA Helicobacter pylori J99 ATP-dependent protease ATP-binding protein NP_222751.1 32798 D 85963 CDS NP_222752.1 15611101 889064 35016..35369 1 NC_000921.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 35369 panD 889064 panD Helicobacter pylori J99 aspartate alpha-decarboxylase NP_222752.1 35016 D 85963 CDS NP_222753.1 15611102 888974 35372..35674 1 NC_000921.1 similar to H. pylori 26695 gene HP0035; hypothetical protein 35674 888974 jhp0031 Helicobacter pylori J99 hypothetical protein NP_222753.1 35372 D 85963 CDS NP_222754.1 15611103 889165 35671..36678 1 NC_000921.1 similar to H. pylori 26695 gene HP0036; hypothetical protein 36678 889165 jhp0032 Helicobacter pylori J99 hypothetical protein NP_222754.1 35671 D 85963 CDS NP_222755.1 15611104 889202 36686..37741 1 NC_000921.1 similar to H. pylori 26695 gene HP0037; hypothetical protein 37741 889202 jhp0033 Helicobacter pylori J99 hypothetical protein NP_222755.1 36686 D 85963 CDS NP_222756.1 15611105 889161 37867..38610 1 NC_000921.1 similar to H. pylori 26695 gene HP0038; DNA transformation competancy 38610 comB1 889161 comB1 Helicobacter pylori J99 DNA transformation competancy NP_222756.1 37867 D 85963 CDS NP_222757.1 15611106 889184 38610..39596 1 NC_000921.1 similar to H. pylori 26695 gene HP0039 and HP0040; DNA transformation compentancy 39596 comB2 889184 comB2 Helicobacter pylori J99 DNA transformation compentancy NP_222757.1 38610 D 85963 CDS NP_222758.1 15611107 889038 39589..40719 1 NC_000921.1 similar to H. pylori 26695 gene HP0041 and HP0042; DNA transformation compentancy 40719 comB3 889038 comB3 Helicobacter pylori J99 DNA transformation compentancy NP_222758.1 39589 D 85963 CDS NP_222759.1 15611108 889003 40789..42201 1 NC_000921.1 similar to H. pylori 26695 gene HP0043; phosphomannose isomerase/GDP-mannose pyrophosphorylase 42201 manC 889003 manC Helicobacter pylori J99 phosphomannose isomerase/GDP-mannose pyrophosphorylase NP_222759.1 40789 D 85963 CDS NP_222760.1 15611109 889028 42242..43387 1 NC_000921.1 similar to H. pylori 26695 gene HP0044; GDP-D-mannose dehydratase 43387 gmd 889028 gmd Helicobacter pylori J99 GDP-D-mannose dehydratase NP_222760.1 42242 D 85963 CDS NP_222761.1 15611110 888984 43380..44312 1 NC_000921.1 similar to H. pylori 26695 gene HP0045; sugar nucleotide biosynthesis 44312 888984 jhp0039 Helicobacter pylori J99 sugar nucleotide biosynthesis NP_222761.1 43380 D 85963 CDS NP_222762.1 15611111 889280 complement(45190..46188) 1 NC_000921.1 similar to H. pylori 26695 gene HP0047; hydrogenase expression/formation protein 46188 hypE 889280 hypE Helicobacter pylori J99 hydrogenase expression/formation protein NP_222762.1 45190 R 85963 CDS NP_222763.1 15611112 890251 complement(46191..48464) 1 NC_000921.1 similar to H. pylori 26695 gene HP0048; transcriptional regulator 48464 890251 jhp0041 Helicobacter pylori J99 transcriptional regulator NP_222763.1 46191 R 85963 CDS NP_222764.1 15611113 890068 complement(48440..49432) 1 NC_000921.1 similar to H. pylori 26695 gene HP0049; hypothetical protein 49432 890068 jhp0042 Helicobacter pylori J99 hypothetical protein NP_222764.1 48440 R 85963 CDS NP_222765.1 15611114 889366 complement(49491..50183) 1 NC_000921.1 similar to H. pylori 26695 gene HP0050; type II DNA modification enzyme 50183 889366 jhp0043 Helicobacter pylori J99 type II DNA modification enzyme NP_222765.1 49491 R 85963 CDS NP_222766.1 15611115 889369 complement(50161..50718) 1 NC_000921.1 type II DNA modification enzyme 50718 889369 jhp0044 Helicobacter pylori J99 type II DNA modification enzyme NP_222766.1 50161 R 85963 CDS NP_222767.1 15611116 889340 complement(51152..52183) 1 NC_000921.1 type II DNA modification enzyme 52183 889340 jhp0045 Helicobacter pylori J99 type II DNA modification enzyme NP_222767.1 51152 R 85963 CDS NP_222768.1 15611117 889327 complement(52193..52975) 1 NC_000921.1 type II restriction enzyme 52975 889327 jhp0046 Helicobacter pylori J99 type II restriction enzyme NP_222768.1 52193 R 85963 CDS NP_222769.1 15611118 890457 complement(53403..54893) 1 NC_000921.1 similar to H. pylori 26695 gene HP0055; sodium/proline symporter 54893 putP 890457 putP Helicobacter pylori J99 sodium/proline symporter NP_222769.1 53403 R 85963 CDS NP_222770.1 15611119 890440 complement(54920..58477) 1 NC_000921.1 similar to H. pylori 26695 gene HP0056; proline/pyrroline-5-carboxylate dehydrogenase 58477 putA 890440 putA Helicobacter pylori J99 proline/pyrroline-5-carboxylate dehydrogenase NP_222770.1 54920 R 85963 CDS NP_222771.1 15611120 890461 58798..59007 1 NC_000921.1 similar to H. pylori 26695 gene HP0057; hypothetical protein 59007 890461 jhp0049 Helicobacter pylori J99 hypothetical protein NP_222771.1 58798 D 85963 CDS NP_222772.1 15611121 890430 59335..59997 1 NC_000921.1 similar to H. pylori 26695 gene HP0058; hypothetical protein 59997 890430 jhp0050 Helicobacter pylori J99 hypothetical protein NP_222772.1 59335 D 85963 CDS NP_222773.1 15611122 890443 60127..60489 1 NC_000921.1 similar to H. pylori 26695 gene HP0058; hypothetical protein 60489 890443 jhp0051 Helicobacter pylori J99 hypothetical protein NP_222773.1 60127 D 85963 CDS NP_222774.1 15611123 890447 60490..61473 1 NC_000921.1 similar to H. pylori 26695 gene HP0059; hypothetical protein 61473 890447 jhp0052 Helicobacter pylori J99 hypothetical protein NP_222774.1 60490 D 85963 CDS NP_222775.1 15611124 890453 61484..61915 1 NC_000921.1 similar to H. pylori 26695 gene HP0060; hypothetical protein 61915 890453 jhp0053 Helicobacter pylori J99 hypothetical protein NP_222775.1 61484 D 85963 CDS NP_222776.1 15611125 890444 62096..63664 1 NC_000921.1 similar to H. pylori 26695 gene HP0060; hypothetical protein 63664 890444 jhp0054 Helicobacter pylori J99 hypothetical protein NP_222776.1 62096 D 85963 CDS NP_222777.1 15611126 890449 63665..63901 1 NC_000921.1 similar to H. pylori 26695 gene HP0060; hypothetical protein 63901 890449 jhp0055 Helicobacter pylori J99 hypothetical protein NP_222777.1 63665 D 85963 CDS NP_222778.1 15611127 890441 63898..64467 1 NC_000921.1 similar to H. pylori 26695 gene HP0061; hypothetical protein 64467 890441 jhp0056 Helicobacter pylori J99 hypothetical protein NP_222778.1 63898 D 85963 CDS NP_222779.1 15611128 890429 64483..64743 1 NC_000921.1 similar to H. pylori 26695 gene HP0062; hypothetical protein 64743 890429 jhp0057 Helicobacter pylori J99 hypothetical protein NP_222779.1 64483 D 85963 CDS NP_222780.1 15611129 890432 64754..66256 1 NC_000921.1 similar to H. pylori 26695 gene HP0063; hypothetical protein 66256 890432 jhp0058 Helicobacter pylori J99 hypothetical protein NP_222780.1 64754 D 85963 CDS NP_222781.1 15611130 890437 66226..66645 1 NC_000921.1 similar to H. pylori 26695 gene HP0064; hypothetical protein 66645 890437 jhp0059 Helicobacter pylori J99 hypothetical protein NP_222781.1 66226 D 85963 CDS NP_222782.1 15611131 890425 66647..67000 1 NC_000921.1 similar to H. pylori 26695 gene HP0065; hypothetical protein 67000 890425 jhp0060 Helicobacter pylori J99 hypothetical protein NP_222782.1 66647 D 85963 CDS NP_222783.1 15611132 890428 66993..69413 1 NC_000921.1 similar to H. pylori 26695 gene HP0066; hypothetical protein 69413 890428 jhp0061 Helicobacter pylori J99 hypothetical protein NP_222783.1 66993 D 85963 CDS NP_222784.1 15611133 890427 complement(69487..70284) 1 NC_000921.1 similar to H. pylori 26695 gene HP0067; urease accessory protein 70284 ureH 890427 ureH Helicobacter pylori J99 urease accessory protein NP_222784.1 69487 R 85963 CDS NP_222785.1 15611134 890411 complement(70284..70883) 1 NC_000921.1 similar to H. pylori 26695 gene HP0068; urease accessory protein 70883 ureG 890411 ureG Helicobacter pylori J99 urease accessory protein NP_222785.1 70284 R 85963 CDS NP_222786.1 15611135 890419 complement(70912..71682) 1 NC_000921.1 similar to H. pylori 26695 gene HP0069; urease accessory protein 71682 ureF 890419 ureF Helicobacter pylori J99 urease accessory protein NP_222786.1 70912 R 85963 CDS NP_222787.1 15611136 890417 complement(71706..72218) 1 NC_000921.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 72218 ureE 890417 ureE Helicobacter pylori J99 urease accessory protein UreE NP_222787.1 71706 R 85963 CDS NP_222788.1 15611137 890415 complement(72220..72807) 1 NC_000921.1 similar to H. pylori 26695 gene HP0071; urea transporter 72807 ureI 890415 ureI Helicobacter pylori J99 urea transporter NP_222788.1 72220 R 85963 CDS NP_222789.1 15611138 890410 complement(73031..74740) 1 NC_000921.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta 74740 ureB 890410 ureB Helicobacter pylori J99 urease subunit beta NP_222789.1 73031 R 85963 CDS NP_222790.1 15611139 890414 complement(74744..75460) 1 NC_000921.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha 75460 ureA 890414 ureA Helicobacter pylori J99 urease subunit alpha NP_222790.1 74744 R 85963 CDS NP_222791.1 15611140 890403 complement(75814..76305) 1 NC_000921.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 76305 lspA 890403 lspA Helicobacter pylori J99 lipoprotein signal peptidase NP_222791.1 75814 R 85963 CDS NP_222792.1 15611141 890406 complement(76299..77636) 1 NC_000921.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 77636 glmM 890406 glmM Helicobacter pylori J99 phosphoglucosamine mutase NP_222792.1 76299 R 85963 CDS NP_222793.1 15611142 890395 77726..77995 1 NC_000921.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 77995 rpsT 890395 rpsT Helicobacter pylori J99 30S ribosomal protein S20 NP_222793.1 77726 D 85963 CDS NP_222794.1 15611143 890378 78114..79172 1 NC_000921.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 79172 prfA 890378 prfA Helicobacter pylori J99 peptide chain release factor 1 NP_222794.1 78114 D 85963 CDS NP_222795.1 15611144 890384 79586..80353 1 NC_000921.1 similar to H. pylori 26695 gene HP0078 and HP0079; hypothetical protein 80353 890384 jhp0073 Helicobacter pylori J99 hypothetical protein NP_222795.1 79586 D 85963 CDS NP_222796.1 15611145 890392 80604..82376 1 NC_000921.1 similar to H. pylori 26695 gene HP0080; hypothetical protein 82376 890392 jhp0074 Helicobacter pylori J99 hypothetical protein NP_222796.1 80604 D 85963 CDS NP_222797.1 15611146 890393 complement(82800..84821) 1 NC_000921.1 similar to H. pylori 26695 gene HP0082; methyl-accepting chemotaxis protein (MCP) 84821 890393 jhp0075 Helicobacter pylori J99 methyl-accepting chemotaxis protein (MCP) NP_222797.1 82800 R 85963 CDS NP_222798.1 15611147 890396 complement(84971..85360) 1 NC_000921.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 85360 rpsI 890396 rpsI Helicobacter pylori J99 30S ribosomal protein S9 NP_222798.1 84971 R 85963 CDS NP_222799.1 15611148 890381 complement(85357..85782) 1 NC_000921.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 85782 rplM 890381 rplM Helicobacter pylori J99 50S ribosomal protein L13 NP_222799.1 85357 R 85963 CDS NP_222800.1 15611149 890388 complement(86134..86322) 1 NC_000921.1 similar to H. pylori 26695 gene HP0085; hypothetical protein 86322 890388 jhp0078 Helicobacter pylori J99 hypothetical protein NP_222800.1 86134 R 85963 CDS NP_222801.1 15611150 890383 complement(86329..87681) 1 NC_000921.1 similar to H. pylori 26695 gene HP0086; hypothetical protein 87681 890383 jhp0079 Helicobacter pylori J99 hypothetical protein NP_222801.1 86329 R 85963 CDS NP_222802.1 15611151 890385 complement(87735..89108) 1 NC_000921.1 similar to H. pylori 26695 gene HP0087; hypothetical protein 89108 890385 jhp0080 Helicobacter pylori J99 hypothetical protein NP_222802.1 87735 R 85963 CDS NP_222803.1 15611152 890377 complement(89128..91173) 1 NC_000921.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 91173 rpoD 890377 rpoD Helicobacter pylori J99 RNA polymerase sigma factor RpoD NP_222803.1 89128 R 85963 CDS NP_222804.1 15611153 889391 complement(91396..92088) 1 NC_000921.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 92088 889391 jhp0082 Helicobacter pylori J99 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NP_222804.1 91396 R 85963 CDS NP_222805.1 15611154 890372 complement(92102..93031) 1 NC_000921.1 similar to H. pylori 26695 gene HP0090; ACP S-malonyltransferase 93031 fabD 890372 fabD Helicobacter pylori J99 ACP S-malonyltransferase NP_222805.1 92102 R 85963 CDS NP_222806.1 15611155 890368 94286..95119 1 NC_000921.1 similar to H. pylori 26695 gene HP0092; type II DNA modification (methyltransferase 95119 890368 jhp0085 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_222806.1 94286 D 85963 CDS NP_222807.1 15611156 890370 complement(join(95139..95642,95644..96039)) 1 NC_000921.1 similar to TIGR HP0094; expression of this protein is predicted to be regulated by slipped-strand repair at the (C) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; alpha(1,2)fucosyltransferase 96039 890370 jhp0086 Helicobacter pylori J99 alpha(1,2)fucosyltransferase NP_222807.1 95139 R 85963 CDS NP_222808.1 15611157 890362 complement(96135..96665) 1 NC_000921.1 similar to H. pylori 26695 gene HP0095; hypothetical protein 96665 890362 jhp0087 Helicobacter pylori J99 hypothetical protein NP_222808.1 96135 R 85963 CDS NP_222809.1 15611158 890365 96738..97682 1 NC_000921.1 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 97682 890365 jhp0088 Helicobacter pylori J99 2-hydroxyacid dehydrogenase NP_222809.1 96738 D 85963 CDS NP_222810.1 15611159 889352 complement(97806..98519) 1 NC_000921.1 similar to H. pylori 26695 gene HP0097; hypothetical protein 98519 889352 jhp0089 Helicobacter pylori J99 hypothetical protein NP_222810.1 97806 R 85963 CDS NP_222811.1 15611160 889337 complement(98623..100083) 1 NC_000921.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 100083 thrC 889337 thrC Helicobacter pylori J99 threonine synthase NP_222811.1 98623 R 85963 CDS NP_222812.1 15611161 889512 100277..102304 1 NC_000921.1 similar to H. pylori 26695 gene HP0099; methyl-accepting chemotaxis protein (MCP) 102304 889512 jhp0091 Helicobacter pylori J99 methyl-accepting chemotaxis protein (MCP) NP_222812.1 100277 D 85963 CDS NP_222813.1 15611162 889190 102304..103410 1 NC_000921.1 similar to H. pylori 26695 gene HP0100; hypothetical protein 103410 889190 jhp0092 Helicobacter pylori J99 hypothetical protein NP_222813.1 102304 D 85963 CDS NP_222814.1 15611163 889370 103627..104388 1 NC_000921.1 similar to H. pylori 26695 gene HP0101; hypothetical protein 104388 889370 jhp0093 Helicobacter pylori J99 hypothetical protein NP_222814.1 103627 D 85963 CDS NP_222815.1 15611164 889376 complement(104371..105153) 1 NC_000921.1 similar to H. pylori 26695 gene HP0102; hypothetical protein 105153 889376 jhp0094 Helicobacter pylori J99 hypothetical protein NP_222815.1 104371 R 85963 CDS NP_222816.1 15611165 889481 complement(105185..106879) 1 NC_000921.1 similar to H. pylori 26695 gene HP0103; methyl-accepting chemotaxis protein (MCP) 106879 889481 jhp0095 Helicobacter pylori J99 methyl-accepting chemotaxis protein (MCP) NP_222816.1 105185 R 85963 CDS NP_222817.1 15611166 889266 complement(107095..108840) 1 NC_000921.1 similar to H. pylori 26695 gene HP0104; 2',3'-cyclic-nucleotide 2'-phosphodiesterase 108840 cpdB 889266 cpdB Helicobacter pylori J99 2',3'-cyclic-nucleotide 2'-phosphodiesterase NP_222817.1 107095 R 85963 CDS NP_222818.1 15611167 889399 complement(108981..109439) 1 NC_000921.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 109439 889399 jhp0097 Helicobacter pylori J99 S-ribosylhomocysteinase NP_222818.1 108981 R 85963 CDS NP_222819.1 15611168 889500 complement(109477..110619) 1 NC_000921.1 catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase 110619 metB 889500 metB Helicobacter pylori J99 cystathionine gamma-synthase NP_222819.1 109477 R 85963 CDS NP_222820.1 15611169 889513 complement(110644..111561) 1 NC_000921.1 similar to H. pylori 26695 gene HP0107; cysteine synthase 111561 cysK 889513 cysK Helicobacter pylori J99 cysteine synthase NP_222820.1 110644 R 85963 CDS NP_222821.1 15611170 889502 111680..112138 1 NC_000921.1 similar to H. pylori 26695 gene HP0108; hypothetical protein 112138 889502 jhp0100 Helicobacter pylori J99 hypothetical protein NP_222821.1 111680 D 85963 CDS NP_222822.1 15611171 889499 complement(112512..114374) 1 NC_000921.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 114374 dnaK 889499 dnaK Helicobacter pylori J99 molecular chaperone DnaK NP_222822.1 112512 R 85963 CDS NP_222823.1 15611172 889489 complement(114404..114979) 1 NC_000921.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 114979 grpE 889489 grpE Helicobacter pylori J99 heat shock protein GrpE NP_222823.1 114404 R 85963 CDS NP_222824.1 15611173 889507 complement(114979..115779) 1 NC_000921.1 Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor 115779 889507 jhp0103 Helicobacter pylori J99 heat-inducible transcription repressor NP_222824.1 114979 R 85963 CDS NP_222825.1 15611174 889465 116018..116656 1 NC_000921.1 similar to H. pylori 26695 gene HP0112; hypothetical protein 116656 889465 jhp0104 Helicobacter pylori J99 hypothetical protein NP_222825.1 116018 D 85963 CDS NP_222826.1 15611175 889490 116694..116990 1 NC_000921.1 similar to H. pylori 26695 gene HP0113; hypothetical protein 116990 889490 jhp0105 Helicobacter pylori J99 hypothetical protein NP_222826.1 116694 D 85963 CDS NP_222827.1 15611176 889494 complement(117000..118883) 1 NC_000921.1 similar to H. pylori 26695 gene HP0114; hypothetical protein 118883 889494 jhp0106 Helicobacter pylori J99 hypothetical protein NP_222827.1 117000 R 85963 CDS NP_222828.1 15611177 889505 complement(118931..120475) 1 NC_000921.1 FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B 120475 flaB 889505 flaB Helicobacter pylori J99 flagellin B NP_222828.1 118931 R 85963 CDS NP_222829.1 15611178 889464 120641..122851 1 NC_000921.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 122851 topA_1 889464 topA_1 Helicobacter pylori J99 DNA topoisomerase I NP_222829.1 120641 D 85963 CDS NP_222830.1 15611179 889487 122844..123770 1 NC_000921.1 similar to H. pylori 26695 gene HP0117; hypothetical protein 123770 889487 jhp0109 Helicobacter pylori J99 hypothetical protein NP_222830.1 122844 D 85963 CDS NP_222831.1 15611180 889480 complement(123915..125153) 1 NC_000921.1 similar to H. pylori 26695 gene HP0118; hypothetical protein 125153 889480 jhp0110 Helicobacter pylori J99 hypothetical protein NP_222831.1 123915 R 85963 CDS NP_222832.1 15611181 889485 complement(125252..127690) 1 NC_000921.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 127690 ppsA 889485 ppsA Helicobacter pylori J99 phosphoenolpyruvate synthase NP_222832.1 125252 R 85963 CDS NP_222833.1 15611182 889466 127876..128007 1 NC_000921.1 similar to H. pylori 26695 gene HP0122; hypothetical protein 128007 889466 jhp0112 Helicobacter pylori J99 hypothetical protein NP_222833.1 127876 D 85963 CDS NP_222834.1 15611183 889475 128047..129885 1 NC_000921.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 129885 thrS 889475 thrS Helicobacter pylori J99 threonyl-tRNA synthetase NP_222834.1 128047 D 85963 CDS NP_222835.1 15611184 889474 129882..130493 1 NC_000921.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 130493 infC 889474 infC Helicobacter pylori J99 translation initiation factor IF-3 NP_222835.1 129882 D 85963 CDS NP_222836.1 15611185 889467 130474..130668 1 NC_000921.1 similar to H. pylori 26695 gene HP0125; 50S ribosomal protein L35 130668 rpmI 889467 rpmI Helicobacter pylori J99 50S ribosomal protein L35 NP_222836.1 130474 D 85963 CDS NP_222837.1 15611186 889457 130763..131113 1 NC_000921.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 131113 rplT 889457 rplT Helicobacter pylori J99 50S ribosomal protein L20 NP_222837.1 130763 D 85963 CDS NP_222838.1 15611187 889460 131313..132173 1 NC_000921.1 similar to H. pylori 26695 gene HP0127; hypothetical protein 132173 889460 jhp0117 Helicobacter pylori J99 hypothetical protein NP_222838.1 131313 D 85963 CDS NP_222839.1 15611188 889453 132653..133084 1 NC_000921.1 similar to H. pylori 26695 gene HP0129; hypothetical protein 133084 889453 jhp0118 Helicobacter pylori J99 hypothetical protein NP_222839.1 132653 D 85963 CDS NP_222840.1 15611189 889437 133496..134353 1 NC_000921.1 similar to H. pylori 26695 gene HP0130; hypothetical protein 134353 889437 jhp0119 Helicobacter pylori J99 hypothetical protein NP_222840.1 133496 D 85963 CDS NP_222841.1 15611190 889452 complement(134985..136352) 1 NC_000921.1 similar to H. pylori 26695 gene HP0132; L-serine/L-threoninedeaminase 136352 sdaB 889452 sdaB Helicobacter pylori J99 L-serine/L-threoninedeaminase NP_222841.1 134985 R 85963 CDS NP_222842.1 15611191 889459 complement(136352..137593) 1 NC_000921.1 similar to H. pylori 26695 gene HP0133; L-serine transporter 137593 sdaC 889459 sdaC Helicobacter pylori J99 L-serine transporter NP_222842.1 136352 R 85963 CDS NP_222843.1 15611192 889424 137774..139123 1 NC_000921.1 similar to H. pylori 26695 gene HP0134; phospho-2-dehydro-3-deoxyheptonate aldolase 139123 aroF 889424 aroF Helicobacter pylori J99 phospho-2-dehydro-3-deoxyheptonate aldolase NP_222843.1 137774 D 85963 CDS NP_222844.1 15611193 889446 139412..139546 1 NC_000921.1 similar to H. pylori 26695 gene HP0135; hypothetical protein 139546 889446 jhp0123 Helicobacter pylori J99 hypothetical protein NP_222844.1 139412 D 85963 CDS NP_222845.1 15611194 889445 complement(139771..140229) 1 NC_000921.1 similar to H. pylori 26695 gene HP0136; bacterioferritin comigratory protein 140229 bcp 889445 bcp Helicobacter pylori J99 bacterioferritin comigratory protein NP_222845.1 139771 R 85963 CDS NP_222846.1 15611195 889436 complement(140239..140874) 1 NC_000921.1 similar to H. pylori 26695 gene HP0137; hypothetical protein 140874 889436 jhp0125 Helicobacter pylori J99 hypothetical protein NP_222846.1 140239 R 85963 CDS NP_222847.1 15611196 889431 complement(140867..142312) 1 NC_000921.1 similar to H. pylori 26695 gene HP0138; iron-sulfur protein 142312 889431 jhp0126 Helicobacter pylori J99 iron-sulfur protein NP_222847.1 140867 R 85963 CDS NP_222848.1 15611197 889418 complement(142341..143069) 1 NC_000921.1 similar to H. pylori 26695 gene HP0139; hypothetical protein 143069 889418 jhp0127 Helicobacter pylori J99 hypothetical protein NP_222848.1 142341 R 85963 CDS NP_222849.1 15611198 889425 143291..144940 1 NC_000921.1 similar to H. pylori 26695 gene HP0140; L-lactate permease 144940 lldP_1 889425 lldP_1 Helicobacter pylori J99 L-lactate permease NP_222849.1 143291 D 85963 CDS NP_222850.1 15611199 889422 144989..146644 1 NC_000921.1 similar to H. pylori 26695 gene HP0141; L-lactate permease 146644 lldP_2 889422 lldP_2 Helicobacter pylori J99 L-lactate permease NP_222850.1 144989 D 85963 CDS NP_222851.1 15611200 889408 complement(146668..147654) 1 NC_000921.1 similar to H. pylori 26695 gene HP0142; DNA glycosylase MutY 147654 mutY 889408 mutY Helicobacter pylori J99 DNA glycosylase MutY NP_222851.1 146668 R 85963 CDS NP_222852.1 15611201 889427 complement(147655..149103) 1 NC_000921.1 similar to H. pylori 26695 gene HP0143; hypothetical protein 149103 889427 jhp0131 Helicobacter pylori J99 hypothetical protein NP_222852.1 147655 R 85963 CDS NP_222853.1 15611202 889396 149273..150739 1 NC_000921.1 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 150739 fixN 889396 fixN Helicobacter pylori J99 cbb3-type cytochrome c oxidase subunit I NP_222853.1 149273 D 85963 CDS NP_222854.1 15611203 889394 150752..151450 1 NC_000921.1 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 151450 fixO 889394 fixO Helicobacter pylori J99 cbb3-type cytochrome c oxidase subunit II NP_222854.1 150752 D 85963 CDS NP_222855.1 15611204 889412 151461..151679 1 NC_000921.1 similar to H. pylori 26695 gene HP0146; cytochrome oxidase (CBB3-type) 151679 fixQ 889412 fixQ Helicobacter pylori J99 cytochrome oxidase (CBB3-type) NP_222855.1 151461 D 85963 CDS NP_222856.1 15611205 889413 151681..152559 1 NC_000921.1 similar to H. pylori 26695 gene HP0147; cytochrome oxidase (CBB3-type) 152559 fixP 889413 fixP Helicobacter pylori J99 cytochrome oxidase (CBB3-type) NP_222856.1 151681 D 85963 CDS NP_222857.1 15611206 889395 152570..152776 1 NC_000921.1 similar to H. pylori 26695 gene HP0148; hypothetical protein 152776 889395 jhp0136 Helicobacter pylori J99 hypothetical protein NP_222857.1 152570 D 85963 CDS NP_222858.1 15611207 889390 152877..153470 1 NC_000921.1 similar to H. pylori 26695 gene HP0149; hypothetical protein 153470 889390 jhp0137 Helicobacter pylori J99 hypothetical protein NP_222858.1 152877 D 85963 CDS NP_222859.1 15611208 889333 153483..154064 1 NC_000921.1 similar to H. pylori 26695 gene HP0150; hypothetical protein 154064 889333 jhp0138 Helicobacter pylori J99 hypothetical protein NP_222859.1 153483 D 85963 CDS NP_222860.1 15611209 889384 154676..155443 1 NC_000921.1 similar to H. pylori 26695 gene HP0151; hypothetical protein 155443 889384 jhp0139 Helicobacter pylori J99 hypothetical protein NP_222860.1 154676 D 85963 CDS NP_222861.1 15611210 889328 complement(155440..156303) 1 NC_000921.1 similar to H. pylori 26695 gene HP0152; hypothetical protein 156303 889328 jhp0140 Helicobacter pylori J99 hypothetical protein NP_222861.1 155440 R 85963 CDS NP_222862.1 15611211 889380 156402..157445 1 NC_000921.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 157445 recA 889380 recA Helicobacter pylori J99 recombinase A NP_222862.1 156402 D 85963 CDS NP_222863.1 15611212 889368 157457..158737 1 NC_000921.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 158737 eno 889368 eno Helicobacter pylori J99 phosphopyruvate hydratase NP_222863.1 157457 D 85963 CDS NP_222864.1 15611213 889323 158730..159005 1 NC_000921.1 similar to H. pylori 26695 gene HP0155; hypothetical protein 159005 889323 jhp0143 Helicobacter pylori J99 hypothetical protein NP_222864.1 158730 D 85963 CDS NP_222865.1 15611214 889324 159022..159618 1 NC_000921.1 similar to H. pylori 26695 gene HP0156; hypothetical protein 159618 889324 jhp0144 Helicobacter pylori J99 hypothetical protein NP_222865.1 159022 D 85963 CDS NP_222866.1 15611215 889302 159623..160111 1 NC_000921.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 160111 aroK 889302 aroK Helicobacter pylori J99 shikimate kinase NP_222866.1 159623 D 85963 CDS NP_222867.1 15611216 889319 160133..161089 1 NC_000921.1 similar to H. pylori 26695 gene HP0158; hypothetical protein 161089 889319 jhp0146 Helicobacter pylori J99 hypothetical protein NP_222867.1 160133 D 85963 CDS NP_222868.1 15611217 889315 complement(161086..162219) 1 NC_000921.1 similar to H. pylori 26695 gene HP0159; lipopolysaccharide biosynthesis protein 162219 889315 jhp0147 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_222868.1 161086 R 85963 CDS NP_222869.1 15611218 889026 162372..163289 1 NC_000921.1 similar to H. pylori 26695 gene HP0160; hypothetical protein 163289 889026 jhp0148 Helicobacter pylori J99 hypothetical protein NP_222869.1 162372 D 85963 CDS NP_222870.1 15611219 889158 complement(163970..164692) 1 NC_000921.1 similar to H. pylori 26695 gene HP0162; hypothetical protein 164692 889158 jhp0149 Helicobacter pylori J99 hypothetical protein NP_222870.1 163970 R 85963 CDS NP_222871.1 15611220 889168 complement(164693..165664) 1 NC_000921.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 165664 hemB 889168 hemB Helicobacter pylori J99 delta-aminolevulinic acid dehydratase NP_222871.1 164693 R 85963 CDS NP_222872.1 15611221 889195 complement(165686..167014) 1 NC_000921.1 similar to H. pylori 26695 gene HP0164 and HP0165; histidine kinase sensor protein 167014 889195 jhp0151 Helicobacter pylori J99 histidine kinase sensor protein NP_222872.1 165686 R 85963 CDS NP_222873.1 15611222 889237 complement(167040..167717) 1 NC_000921.1 similar to H. pylori 26695 gene HP0166; transcriptional regulator 167717 889237 jhp0152 Helicobacter pylori J99 transcriptional regulator NP_222873.1 167040 R 85963 CDS NP_222874.1 15611223 889277 complement(168125..168598) 1 NC_000921.1 similar to H. pylori 26695 gene HP0167; hypothetical protein 168598 889277 jhp0153 Helicobacter pylori J99 hypothetical protein NP_222874.1 168125 R 85963 CDS NP_222875.1 15611224 888981 complement(168577..168840) 1 NC_000921.1 similar to H. pylori 26695 gene HP0168; hypothetical protein 168840 888981 jhp0154 Helicobacter pylori J99 hypothetical protein NP_222875.1 168577 R 85963 CDS NP_222876.1 15611225 889162 complement(168887..170155) 1 NC_000921.1 similar to H. pylori 26695 gene HP0169; protease 170155 889162 jhp0155 Helicobacter pylori J99 protease NP_222876.1 168887 R 85963 CDS NP_222877.1 15611226 889318 complement(170158..170889) 1 NC_000921.1 similar to H. pylori 26695 gene HP0170; hypothetical protein 170889 889318 jhp0156 Helicobacter pylori J99 hypothetical protein NP_222877.1 170158 R 85963 CDS NP_222878.1 15611227 889002 complement(170959..172050) 1 NC_000921.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 172050 prfB 889002 prfB Helicobacter pylori J99 peptide chain release factor 2 NP_222878.1 170959 R 85963 CDS NP_222879.1 15611228 888998 complement(172111..173283) 1 NC_000921.1 similar to H. pylori 26695 gene HP0172; molybdopterin biosynthesis protein 173283 moeA 888998 moeA Helicobacter pylori J99 molybdopterin biosynthesis protein NP_222879.1 172111 R 85963 CDS NP_222880.1 15611229 889004 complement(173293..174060) 1 NC_000921.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 174060 fliR 889004 fliR Helicobacter pylori J99 flagellar biosynthesis protein FliR NP_222880.1 173293 R 85963 CDS NP_222881.1 15611230 888983 complement(174054..174782) 1 NC_000921.1 similar to H. pylori 26695 gene HP0174; hypothetical protein 174782 888983 jhp0160 Helicobacter pylori J99 hypothetical protein NP_222881.1 174054 R 85963 CDS NP_222882.1 15611231 890358 175251..176150 1 NC_000921.1 similar to H. pylori 26695 gene HP0175; peptidyl-prolyl cis-trans isomerase 176150 890358 jhp0161 Helicobacter pylori J99 peptidyl-prolyl cis-trans isomerase NP_222882.1 175251 D 85963 CDS NP_222883.1 15611232 889011 176164..177087 1 NC_000921.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 177087 fba 889011 fba Helicobacter pylori J99 fructose-bisphosphate aldolase NP_222883.1 176164 D 85963 CDS NP_222884.1 15611233 889300 177109..177672 1 NC_000921.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 177672 efp 889300 efp Helicobacter pylori J99 elongation factor P NP_222884.1 177109 D 85963 CDS NP_222885.1 15611234 890357 178219..179565 1 NC_000921.1 restriction enzyme 179565 890357 jhp0164 Helicobacter pylori J99 restriction enzyme NP_222885.1 178219 D 85963 CDS NP_222886.1 15611235 889243 179558..180778 1 NC_000921.1 hypothetical protein 180778 889243 jhp0165 Helicobacter pylori J99 hypothetical protein NP_222886.1 179558 D 85963 CDS NP_222887.1 15611236 890359 complement(180850..181872) 1 NC_000921.1 similar to H. pylori 26695 gene HP0178; sialic acid synthase 181872 neuB 890359 neuB Helicobacter pylori J99 sialic acid synthase NP_222887.1 180850 R 85963 CDS NP_222888.1 15611237 889252 complement(181875..182516) 1 NC_000921.1 similar to H. pylori 26695 gene HP0179; ABC transporter ATP-binding protein 182516 889252 jhp0167 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_222888.1 181875 R 85963 CDS NP_222889.1 15611238 889290 complement(182513..183790) 1 NC_000921.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 183790 lnt 889290 lnt Helicobacter pylori J99 apolipoprotein N-acyltransferase NP_222889.1 182513 R 85963 CDS NP_222890.1 15611239 889255 184026..184736 1 NC_000921.1 similar to H. pylori 26695 gene HP0181; hypothetical protein 184736 889255 jhp0169 Helicobacter pylori J99 hypothetical protein NP_222890.1 184026 D 85963 CDS NP_222891.1 15611240 889288 184746..186251 1 NC_000921.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 186251 lysS 889288 lysS Helicobacter pylori J99 lysyl-tRNA synthetase NP_222891.1 184746 D 85963 CDS NP_222892.1 15611241 889253 186251..187501 1 NC_000921.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 187501 glyA 889253 glyA Helicobacter pylori J99 serine hydroxymethyltransferase NP_222892.1 186251 D 85963 CDS NP_222893.1 15611242 889316 187511..188053 1 NC_000921.1 similar to H. pylori 26695 gene HP0184; hypothetical protein 188053 889316 jhp0172 Helicobacter pylori J99 hypothetical protein NP_222893.1 187511 D 85963 CDS NP_222894.1 15611243 889317 188075..188881 1 NC_000921.1 similar to H. pylori 26695 gene HP0185; hypothetical protein 188881 889317 jhp0173 Helicobacter pylori J99 hypothetical protein NP_222894.1 188075 D 85963 CDS NP_222895.1 15611244 889291 complement(189273..190976) 1 NC_000921.1 similar to H. pylori 26695 gene HP0186, HP0187, and HP0188; hypothetical protein 190976 889291 jhp0174 Helicobacter pylori J99 hypothetical protein NP_222895.1 189273 R 85963 CDS NP_222896.1 15611245 889241 191132..191665 1 NC_000921.1 similar to H. pylori 26695 gene HP0189; hypothetical protein 191665 889241 jhp0175 Helicobacter pylori J99 hypothetical protein NP_222896.1 191132 D 85963 CDS NP_222897.1 15611246 889240 complement(191672..193180) 1 NC_000921.1 similar to H. pylori 26695 gene HP0190; cardiolipin synthase 193180 889240 jhp0176 Helicobacter pylori J99 cardiolipin synthase NP_222897.1 191672 R 85963 CDS NP_222898.1 15611247 889211 complement(193202..193939) 1 NC_000921.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 193939 frdB 889211 frdB Helicobacter pylori J99 fumarate reductase iron-sulfur subunit NP_222898.1 193202 R 85963 CDS NP_222899.1 15611248 889257 complement(193932..196076) 1 NC_000921.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 196076 frdA 889257 frdA Helicobacter pylori J99 fumarate reductase flavoprotein subunit NP_222899.1 193932 R 85963 CDS NP_222900.1 15611249 890355 complement(196086..196853) 1 NC_000921.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit 196853 frdC 890355 frdC Helicobacter pylori J99 fumarate reductase cytochrome b-556 subunit NP_222900.1 196086 R 85963 CDS NP_222901.1 15611250 889254 197063..197767 1 NC_000921.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 197767 tpiA 889254 tpiA Helicobacter pylori J99 triosephosphate isomerase NP_222901.1 197063 D 85963 CDS NP_222902.1 15611251 889293 197777..198604 1 NC_000921.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 198604 fabI 889293 fabI Helicobacter pylori J99 enoyl-ACP reductase NP_222902.1 197777 D 85963 CDS NP_222903.1 15611252 889285 198614..199624 1 NC_000921.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 199624 lpxD 889285 lpxD Helicobacter pylori J99 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_222903.1 198614 D 85963 CDS NP_222904.1 15611253 889174 199690..200847 1 NC_000921.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 200847 metK 889174 metK Helicobacter pylori J99 S-adenosylmethionine synthetase NP_222904.1 199690 D 85963 CDS NP_222905.1 15611254 889157 200914..201327 1 NC_000921.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 201327 ndk 889157 ndk Helicobacter pylori J99 nucleoside diphosphate kinase NP_222905.1 200914 D 85963 CDS NP_222906.1 15611255 890023 201352..201708 1 NC_000921.1 similar to H. pylori 26695 gene HP0199; hypothetical protein 201708 890023 jhp0185 Helicobacter pylori J99 hypothetical protein NP_222906.1 201352 D 85963 CDS NP_222907.1 15611256 890231 201724..201870 1 NC_000921.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 201870 rpmF 890231 rpmF Helicobacter pylori J99 50S ribosomal protein L32 NP_222907.1 201724 D 85963 CDS NP_222908.1 15611257 889154 201948..202967 1 NC_000921.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 202967 plsX 889154 plsX Helicobacter pylori J99 glycerol-3-phosphate acyltransferase PlsX NP_222908.1 201948 D 85963 CDS NP_222909.1 15611258 889248 202991..203986 1 NC_000921.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 203986 fabH 889248 fabH Helicobacter pylori J99 3-oxoacyl-ACP synthase NP_222909.1 202991 D 85963 CDS NP_222910.1 15611259 889247 204010..204312 1 NC_000921.1 similar to H. pylori 26695 gene HP0203; hypothetical protein 204312 889247 jhp0189 Helicobacter pylori J99 hypothetical protein NP_222910.1 204010 D 85963 CDS NP_222911.1 15611260 889301 complement(205002..205385) 1 NC_000921.1 similar to H. pylori 26695 gene HP0204; hypothetical protein 205385 889301 jhp0190 Helicobacter pylori J99 hypothetical protein NP_222911.1 205002 R 85963 CDS NP_222912.1 15611261 889309 complement(205463..208213) 1 NC_000921.1 similar to H. pylori 26695 gene HP0205; hypothetical protein 208213 889309 jhp0191 Helicobacter pylori J99 hypothetical protein NP_222912.1 205463 R 85963 CDS NP_222913.1 15611262 889308 complement(208250..208507) 1 NC_000921.1 similar to H. pylori 26695 gene HP0206; hypothetical protein 208507 889308 jhp0192 Helicobacter pylori J99 hypothetical protein NP_222913.1 208250 R 85963 CDS NP_222914.1 15611263 889295 208604..209710 1 NC_000921.1 similar to H. pylori 26695 gene HP0207; hypothetical protein 209710 889295 jhp0193 Helicobacter pylori J99 hypothetical protein NP_222914.1 208604 D 85963 CDS NP_222915.1 15611264 889249 complement(join(209770..210853,210856..210956)) 1 NC_000921.1 similar to TIGR HP0208; expression of this protein is predicted to be regulated by slipped-strand repair at the (AG) dinucleotide repeat; length of the repeat has been artificially adjusted (removal of one dinucleotide) to give the full length protein; lipopolysaccharide biosynthesis protein 210956 889249 jhp0194 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_222915.1 209770 R 85963 CDS NP_222916.1 15611265 889281 211139..212455 1 NC_000921.1 similar to H. pylori 26695 gene HP0209; hypothetical protein 212455 889281 jhp0195 Helicobacter pylori J99 hypothetical protein NP_222916.1 211139 D 85963 CDS NP_222917.1 15611266 889307 212559..214424 1 NC_000921.1 molecular chaperone; heat shock protein 90 214424 htpG 889307 htpG Helicobacter pylori J99 heat shock protein 90 NP_222917.1 212559 D 85963 CDS NP_222918.1 15611267 889172 complement(214621..215373) 1 NC_000921.1 similar to H. pylori 26695 gene HP0211; hypothetical protein 215373 889172 jhp0197 Helicobacter pylori J99 hypothetical protein NP_222918.1 214621 R 85963 CDS NP_222919.1 15611268 889256 complement(215821..216987) 1 NC_000921.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 216987 dapE 889256 dapE Helicobacter pylori J99 succinyl-diaminopimelate desuccinylase NP_222919.1 215821 R 85963 CDS NP_222920.1 15611269 889262 complement(216997..218862) 1 NC_000921.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 218862 gidA 889262 gidA Helicobacter pylori J99 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_222920.1 216997 R 85963 CDS NP_222921.1 15611270 889217 218958..220604 1 NC_000921.1 similar to H. pylori 26695 gene HP0214; transporter 220604 889217 jhp0200 Helicobacter pylori J99 transporter NP_222921.1 218958 D 85963 CDS NP_222922.1 15611271 889289 220617..221417 1 NC_000921.1 similar to H. pylori 26695 gene HP0215; CDP-diacylglycerol synthase 221417 cdsA 889289 cdsA Helicobacter pylori J99 CDP-diacylglycerol synthase NP_222922.1 220617 D 85963 CDS NP_222923.1 15611272 889284 221418..222524 1 NC_000921.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 222524 889284 jhp0202 Helicobacter pylori J99 1-deoxy-D-xylulose 5-phosphate reductoisomerase NP_222923.1 221418 D 85963 CDS NP_222924.1 15611273 889199 join(222575..223076,223078..223733) 1 NC_000921.1 similar to TIGR HP0217; expression of this protein is predicted to be regulated by slipped-strand repair at the two (G) polynucleotide repeats; length of the second repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; hypothetical protein 223733 889199 jhp0203 Helicobacter pylori J99 hypothetical protein NP_222924.1 222575 D 85963 CDS NP_222925.1 15611274 889092 complement(223802..224353) 1 NC_000921.1 similar to H. pylori 26695 gene HP0218; hypothetical protein 224353 889092 jhp0204 Helicobacter pylori J99 hypothetical protein NP_222925.1 223802 R 85963 CDS NP_222926.1 15611275 889091 224473..224958 1 NC_000921.1 similar to H. pylori 26695 gene HP0219; hypothetical protein 224958 889091 jhp0205 Helicobacter pylori J99 hypothetical protein NP_222926.1 224473 D 85963 CDS NP_222927.1 15611276 889005 225126..226289 1 NC_000921.1 catalyzes the removal of sulfur from cysteine to form alanine; cysteine desulfurase 226289 889005 jhp0206 Helicobacter pylori J99 cysteine desulfurase NP_222927.1 225126 D 85963 CDS NP_222928.1 15611277 889068 226311..227291 1 NC_000921.1 similar to H. pylori 26695 gene HP0221; nifU-like protein 227291 889068 jhp0207 Helicobacter pylori J99 nifU-like protein NP_222928.1 226311 D 85963 CDS NP_222929.1 15611278 889213 227455..227715 1 NC_000921.1 similar to H. pylori 26695 gene HP0222; hypothetical protein 227715 889213 jhp0208 Helicobacter pylori J99 hypothetical protein NP_222929.1 227455 D 85963 CDS NP_222930.1 15611279 889982 227794..229140 1 NC_000921.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 229140 radA 889982 radA Helicobacter pylori J99 DNA repair protein RadA NP_222930.1 227794 D 85963 CDS NP_222931.1 15611280 889429 229264..230343 1 NC_000921.1 this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein 230343 889429 jhp0210 Helicobacter pylori J99 bifunctional methionine sulfoxide reductase A/B protein NP_222931.1 229264 D 85963 CDS NP_222932.1 15611281 889985 complement(230748..231581) 1 NC_000921.1 similar to H. pylori 26695 gene HP0226; hypothetical protein 231581 889985 jhp0211 Helicobacter pylori J99 hypothetical protein NP_222932.1 230748 R 85963 CDS NP_222933.1 15611282 889419 complement(231799..233889) 1 NC_000921.1 similar to H. pylori 26695 gene HP0227; hypothetical protein 233889 889419 jhp0212 Helicobacter pylori J99 hypothetical protein NP_222933.1 231799 R 85963 CDS NP_222934.1 15611283 889984 234143..235300 1 NC_000921.1 similar to H. pylori 26695 gene HP0228; hypothetical protein 235300 889984 jhp0213 Helicobacter pylori J99 hypothetical protein NP_222934.1 234143 D 85963 CDS NP_222935.1 15611284 889426 complement(235542..236993) 1 NC_000921.1 similar to H. pylori 26695 gene HP0229; Outer membrane protein/porin 236993 hopA 889426 hopA Helicobacter pylori J99 Outer membrane protein/porin NP_222935.1 235542 R 85963 CDS NP_222936.1 15611285 889986 complement(237187..237918) 1 NC_000921.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 237918 kdsB 889986 kdsB Helicobacter pylori J99 3-deoxy-manno-octulosonate cytidylyltransferase NP_222936.1 237187 R 85963 CDS NP_222937.1 15611286 889417 238027..238824 1 NC_000921.1 similar to H. pylori 26695 gene HP0231; hypothetical protein 238824 889417 jhp0216 Helicobacter pylori J99 hypothetical protein NP_222937.1 238027 D 85963 CDS NP_222938.1 15611287 889993 238840..239487 1 NC_000921.1 similar to H. pylori 26695 gene HP0232; hypothetical protein 239487 889993 jhp0217 Helicobacter pylori J99 hypothetical protein NP_222938.1 238840 D 85963 CDS NP_222939.1 15611288 889388 239509..240681 1 NC_000921.1 similar to H. pylori 26695 gene HP0233; hypothetical protein 240681 889388 jhp0218 Helicobacter pylori J99 hypothetical protein NP_222939.1 239509 D 85963 CDS NP_222940.1 15611289 889987 240681..241211 1 NC_000921.1 similar to H. pylori 26695 gene HP0234; hypothetical protein 241211 889987 jhp0219 Helicobacter pylori J99 hypothetical protein NP_222940.1 240681 D 85963 CDS NP_222941.1 15611290 889420 complement(241987..243054) 1 NC_000921.1 similar to H. pylori 26695 gene HP0235; hypothetical protein 243054 889420 jhp0220 Helicobacter pylori J99 hypothetical protein NP_222941.1 241987 R 85963 CDS NP_222942.1 15611291 889988 complement(243165..243536) 1 NC_000921.1 similar to H. pylori 26695 gene HP0236; hypothetical protein 243536 889988 jhp0221 Helicobacter pylori J99 hypothetical protein NP_222942.1 243165 R 85963 CDS NP_222943.1 15611292 889411 complement(243536..244456) 1 NC_000921.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 244456 hemC 889411 hemC Helicobacter pylori J99 porphobilinogen deaminase NP_222943.1 243536 R 85963 CDS NP_222944.1 15611293 889989 complement(244467..246197) 1 NC_000921.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 246197 proS 889989 proS Helicobacter pylori J99 prolyl-tRNA synthetase NP_222944.1 244467 R 85963 CDS NP_222945.1 15611294 889414 complement(246201..247550) 1 NC_000921.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 247550 hemA 889414 hemA Helicobacter pylori J99 glutamyl-tRNA reductase NP_222945.1 246201 R 85963 CDS NP_222946.1 15611295 889990 complement(247550..248473) 1 NC_000921.1 similar to H. pylori 26695 gene HP0240; octaprenyl-diphosphate synthase 248473 ispB 889990 ispB Helicobacter pylori J99 octaprenyl-diphosphate synthase NP_222946.1 247550 R 85963 CDS NP_222947.1 15611296 889416 complement(248483..248878) 1 NC_000921.1 similar to H. pylori 26695 gene HP0241; hypothetical protein 248878 889416 jhp0226 Helicobacter pylori J99 hypothetical protein NP_222947.1 248483 R 85963 CDS NP_222948.1 15611297 890000 complement(248871..249155) 1 NC_000921.1 similar to H. pylori 26695 gene HP0242; hypothetical protein 249155 890000 jhp0227 Helicobacter pylori J99 hypothetical protein NP_222948.1 248871 R 85963 CDS NP_222949.1 15611298 889403 complement(249176..249610) 1 NC_000921.1 similar to H. pylori 26695 gene HP0243; neutrophil-activating protein A 249610 napA 889403 napA Helicobacter pylori J99 neutrophil-activating protein A NP_222949.1 249176 R 85963 CDS NP_222950.1 15611299 889991 complement(249818..250963) 1 NC_000921.1 similar to H. pylori 26695 gene HP0244; histidine kinase sensor protein 250963 889991 jhp0229 Helicobacter pylori J99 histidine kinase sensor protein NP_222950.1 249818 R 85963 CDS NP_222951.1 15611300 889415 complement(250960..251277) 1 NC_000921.1 similar to H. pylori 26695 gene HP0245; hypothetical protein 251277 889415 jhp0230 Helicobacter pylori J99 hypothetical protein NP_222951.1 250960 R 85963 CDS NP_222952.1 15611301 889996 complement(251274..252302) 1 NC_000921.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 252302 flgI 889996 flgI Helicobacter pylori J99 flagellar basal body P-ring biosynthesis protein FlgA NP_222952.1 251274 R 85963 CDS NP_222953.1 15611302 889407 252488..253963 1 NC_000921.1 similar to H. pylori 26695 gene HP0247; ATP-dependent RNA helicase DeaD 253963 deaD 889407 deaD Helicobacter pylori J99 ATP-dependent RNA helicase DeaD NP_222953.1 252488 D 85963 CDS NP_222954.1 15611303 889994 253984..255072 1 NC_000921.1 similar to H. pylori 26695 gene HP0248; hypothetical protein 255072 889994 jhp0233 Helicobacter pylori J99 hypothetical protein NP_222954.1 253984 D 85963 CDS NP_222955.1 15611304 889410 255079..255618 1 NC_000921.1 similar to H. pylori 26695 gene HP0249; hypothetical protein 255618 889410 jhp0234 Helicobacter pylori J99 hypothetical protein NP_222955.1 255079 D 85963 CDS NP_222956.1 15611305 889997 complement(255701..257251) 1 NC_000921.1 similar to H. pylori 26695 gene HP0250; ABC transporter ATP-binding protein 257251 889997 jhp0235 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_222956.1 255701 R 85963 CDS NP_222957.1 15611306 889405 complement(257261..258277) 1 NC_000921.1 similar to H. pylori 26695 gene HP0251; ABC transporter permease 258277 889405 jhp0236 Helicobacter pylori J99 ABC transporter permease NP_222957.1 257261 R 85963 CDS NP_222958.1 15611307 889995 258627..260066 1 NC_000921.1 similar to H. pylori 26695 gene HP0252; hypothetical protein 260066 889995 jhp0237 Helicobacter pylori J99 hypothetical protein NP_222958.1 258627 D 85963 CDS NP_222959.1 15611308 889406 260079..261494 1 NC_000921.1 similar to H. pylori 26695 gene HP0253 and HP0254; hypothetical protein 261494 889406 jhp0238 Helicobacter pylori J99 hypothetical protein NP_222959.1 260079 D 85963 CDS NP_222960.1 15611309 889998 261593..262828 1 NC_000921.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 262828 purA 889998 purA Helicobacter pylori J99 adenylosuccinate synthetase NP_222960.1 261593 D 85963 CDS NP_222961.1 15611310 889398 262825..263253 1 NC_000921.1 similar to H. pylori 26695 gene HP0256; hypothetical protein 263253 889398 jhp0240 Helicobacter pylori J99 hypothetical protein NP_222961.1 262825 D 85963 CDS NP_222962.1 15611311 890012 263246..263914 1 NC_000921.1 similar to H. pylori 26695 gene HP0257; hypothetical protein 263914 890012 jhp0241 Helicobacter pylori J99 hypothetical protein NP_222962.1 263246 D 85963 CDS NP_222963.1 15611312 889382 263911..264966 1 NC_000921.1 similar to H. pylori 26695 gene HP0258; hypothetical protein 264966 889382 jhp0242 Helicobacter pylori J99 hypothetical protein NP_222963.1 263911 D 85963 CDS NP_222964.1 15611313 889999 264979..266241 1 NC_000921.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 266241 xseA 889999 xseA Helicobacter pylori J99 exodeoxyribonuclease VII large subunit NP_222964.1 264979 D 85963 CDS NP_222965.1 15611314 889401 complement(266260..267432) 1 NC_000921.1 similar to H. pylori 26695 gene HP0260; type II DNA modification (methyltransferase 267432 889401 jhp0244 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_222965.1 266260 R 85963 CDS NP_222966.1 15611315 890001 complement(267425..267883) 1 NC_000921.1 similar to H. pylori 26695 gene HP0261; hypothetical protein 267883 890001 jhp0245 Helicobacter pylori J99 hypothetical protein NP_222966.1 267425 R 85963 CDS NP_222967.1 15611316 889400 267960..268478 1 NC_000921.1 similar to H. pylori 26695 gene HP0262; hypothetical protein 268478 889400 jhp0246 Helicobacter pylori J99 hypothetical protein NP_222967.1 267960 D 85963 CDS NP_222968.1 15611317 890002 268450..268659 1 NC_000921.1 similar to H. pylori 26695 gene HP0262; hypothetical protein 268659 890002 jhp0247 Helicobacter pylori J99 hypothetical protein NP_222968.1 268450 D 85963 CDS NP_222969.1 15611318 889402 268656..269414 1 NC_000921.1 similar to H. pylori 26695 gene HP0263; type II DNA modification (methyltransferase 269414 889402 jhp0248 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_222969.1 268656 D 85963 CDS NP_222970.1 15611319 890003 269487..272057 1 NC_000921.1 similar to H. pylori 26695 gene HP0264; heat shock protein 272057 clpB 890003 clpB Helicobacter pylori J99 heat shock protein NP_222970.1 269487 D 85963 CDS NP_222971.1 15611320 889397 272114..272833 1 NC_000921.1 similar to H. pylori 26695 gene HP0265; cytochrome C-type biogenesis protein 272833 ccdA 889397 ccdA Helicobacter pylori J99 cytochrome C-type biogenesis protein NP_222971.1 272114 D 85963 CDS NP_222972.1 15611321 890005 272843..273979 1 NC_000921.1 similar to H. pylori 26695 gene HP0266; dihydroorotase 273979 pyrC_1 890005 pyrC_1 Helicobacter pylori J99 dihydroorotase NP_222972.1 272843 D 85963 CDS NP_222973.1 15611322 889393 273964..275193 1 NC_000921.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 275193 orf1 889393 orf1 Helicobacter pylori J99 chlorohydrolase NP_222973.1 273964 D 85963 CDS NP_222974.1 15611323 890004 275440..275682 1 NC_000921.1 similar to H. pylori 26695 gene HP0268; hypothetical protein 275682 890004 jhp0253 Helicobacter pylori J99 hypothetical protein NP_222974.1 275440 D 85963 CDS NP_222975.1 15611324 889392 275692..277005 1 NC_000921.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 277005 889392 jhp0254 Helicobacter pylori J99 (dimethylallyl)adenosine tRNA methylthiotransferase NP_222975.1 275692 D 85963 CDS NP_222976.1 15611325 890008 277039..277692 1 NC_000921.1 similar to H. pylori 26695 gene HP0270; hypothetical protein 277692 890008 jhp0255 Helicobacter pylori J99 hypothetical protein NP_222976.1 277039 D 85963 CDS NP_222977.1 15611326 889389 277685..278668 1 NC_000921.1 similar to H. pylori 26695 gene HP0271; hypothetical protein 278668 889389 jhp0256 Helicobacter pylori J99 hypothetical protein NP_222977.1 277685 D 85963 CDS NP_222978.1 15611327 890006 278658..279191 1 NC_000921.1 similar to H. pylori 26695 gene HP0272; hypothetical protein 279191 890006 jhp0257 Helicobacter pylori J99 hypothetical protein NP_222978.1 278658 D 85963 CDS NP_222979.1 15611328 889386 279188..279727 1 NC_000921.1 similar to H. pylori 26695 gene HP0273; hypothetical protein 279727 889386 jhp0258 Helicobacter pylori J99 hypothetical protein NP_222979.1 279188 D 85963 CDS NP_222980.1 15611329 890007 279744..280142 1 NC_000921.1 similar to H. pylori 26695 gene HP0274; hypothetical protein 280142 890007 jhp0259 Helicobacter pylori J99 hypothetical protein NP_222980.1 279744 D 85963 CDS NP_222981.1 15611330 889385 280179..281474 1 NC_000921.1 similar to H. pylori 26695 gene HP0275; hypothetical protein 281474 889385 jhp0260 Helicobacter pylori J99 hypothetical protein NP_222981.1 280179 D 85963 CDS NP_222982.1 15611331 890009 281462..282019 1 NC_000921.1 similar to H. pylori 26695 gene HP0276; hypothetical protein 282019 890009 jhp0261 Helicobacter pylori J99 hypothetical protein NP_222982.1 281462 D 85963 CDS NP_222983.1 15611332 889387 282076..282330 1 NC_000921.1 similar to H. pylori 26695 gene HP0277; ferredoxin 282330 889387 jhp0262 Helicobacter pylori J99 ferredoxin NP_222983.1 282076 D 85963 CDS NP_222984.1 15611333 890010 282340..283794 1 NC_000921.1 similar to H. pylori 26695 gene HP0278; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 283794 gppA 890010 gppA Helicobacter pylori J99 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase NP_222984.1 282340 D 85963 CDS NP_222985.1 15611334 889379 283791..284801 1 NC_000921.1 similar to H. pylori 26695 gene HP0279; lipopolysaccharide heptosyltransferase-1 284801 waaC 889379 waaC Helicobacter pylori J99 lipopolysaccharide heptosyltransferase-1 NP_222985.1 283791 D 85963 CDS NP_222986.1 15611335 890016 284798..285784 1 NC_000921.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 285784 waaM 890016 waaM Helicobacter pylori J99 lipid A biosynthesis lauroyl acyltransferase NP_222986.1 284798 D 85963 CDS NP_222987.1 15611336 889378 complement(286040..287155) 1 NC_000921.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 287155 tgt 889378 tgt Helicobacter pylori J99 queuine tRNA-ribosyltransferase NP_222987.1 286040 R 85963 CDS NP_222988.1 15611337 890011 287212..288648 1 NC_000921.1 similar to H. pylori 26695 gene HP0282; hypothetical protein 288648 890011 jhp0267 Helicobacter pylori J99 hypothetical protein NP_222988.1 287212 D 85963 CDS NP_222989.1 15611338 889383 288653..289684 1 NC_000921.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 289684 aroB 889383 aroB Helicobacter pylori J99 3-dehydroquinate synthase NP_222989.1 288653 D 85963 CDS NP_222990.1 15611339 889312 289675..291246 1 NC_000921.1 similar to H. pylori 26695 gene HP0284; hypothetical protein 291246 889312 jhp0269 Helicobacter pylori J99 hypothetical protein NP_222990.1 289675 D 85963 CDS NP_222991.1 15611340 890013 291243..292499 1 NC_000921.1 similar to H. pylori 26695 gene HP0285; hypothetical protein 292499 890013 jhp0270 Helicobacter pylori J99 hypothetical protein NP_222991.1 291243 D 85963 CDS NP_222992.1 15611341 889381 292486..294138 1 NC_000921.1 similar to H. pylori 26695 gene HP0286; ATP-dependent zinc metallopeptidase 294138 ftsH_1 889381 ftsH_1 Helicobacter pylori J99 ATP-dependent zinc metallopeptidase NP_222992.1 292486 D 85963 CDS NP_222993.1 15611342 890015 294141..294659 1 NC_000921.1 similar to H. pylori 26695 gene HP0287; hypothetical protein 294659 890015 jhp0272 Helicobacter pylori J99 hypothetical protein NP_222993.1 294141 D 85963 CDS NP_222994.1 15611343 889304 294672..295145 1 NC_000921.1 similar to H. pylori 26695 gene HP0288; hypothetical protein 295145 889304 jhp0273 Helicobacter pylori J99 hypothetical protein NP_222994.1 294672 D 85963 CDS NP_222995.1 15611344 890022 295213..303921 1 NC_000921.1 similar to H. pylori 26695 gene HP0289; vacuolating cytotoxin (VacA) paralog 303921 890022 jhp0274 Helicobacter pylori J99 vacuolating cytotoxin (VacA) paralog NP_222995.1 295213 D 85963 CDS NP_222996.1 15611345 889338 303969..305186 1 NC_000921.1 similar to H. pylori 26695 gene HP0290; diaminopimelate decarboxylase 305186 lysA 889338 lysA Helicobacter pylori J99 diaminopimelate decarboxylase NP_222996.1 303969 D 85963 CDS NP_222997.1 15611346 890014 305191..305493 1 NC_000921.1 similar to H. pylori 26695 gene HP0291; hypothetical protein 305493 890014 jhp0276 Helicobacter pylori J99 hypothetical protein NP_222997.1 305191 D 85963 CDS NP_222998.1 15611347 890017 305506..306378 1 NC_000921.1 similar to H. pylori 26695 gene HP0292; hypothetical protein 306378 890017 jhp0277 Helicobacter pylori J99 hypothetical protein NP_222998.1 305506 D 85963 CDS NP_222999.1 15611348 889377 306379..308082 1 NC_000921.1 similar to H. pylori 26695 gene HP0293; p-aminobenzoate synthetase 308082 pabB 889377 pabB Helicobacter pylori J99 p-aminobenzoate synthetase NP_222999.1 306379 D 85963 CDS NP_223000.1 15611349 890018 308210..309229 1 NC_000921.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 309229 amiE 890018 amiE Helicobacter pylori J99 acylamide amidohydrolase NP_223000.1 308210 D 85963 CDS NP_223001.1 15611350 890250 complement(309554..312040) 1 NC_000921.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL 312040 flgL 890250 flgL Helicobacter pylori J99 flagellar hook-associated protein FlgL NP_223001.1 309554 R 85963 CDS NP_223002.1 15611351 890019 312283..312597 1 NC_000921.1 similar to H. pylori 26695 gene HP0296; 50S ribosomal protein L21 312597 rplU 890019 rplU Helicobacter pylori J99 50S ribosomal protein L21 NP_223002.1 312283 D 85963 CDS NP_223003.1 15611352 889314 312611..312877 1 NC_000921.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 312877 rpmA 889314 rpmA Helicobacter pylori J99 50S ribosomal protein L27 NP_223003.1 312611 D 85963 CDS NP_223004.1 15611353 890285 312996..314636 1 NC_000921.1 similar to H. pylori 26695 gene HP0298; periplasmic dipeptide transport substrate-binding protein 314636 dppA 890285 dppA Helicobacter pylori J99 periplasmic dipeptide transport substrate-binding protein NP_223004.1 312996 D 85963 CDS NP_223005.1 15611354 890020 314647..315651 1 NC_000921.1 similar to H. pylori 26695 gene HP0299; peptide ABC transporter permease 315651 dppB 890020 dppB Helicobacter pylori J99 peptide ABC transporter permease NP_223005.1 314647 D 85963 CDS NP_223006.1 15611355 890021 316516..317379 1 NC_000921.1 similar to H. pylori 26695 gene HP0301; peptide ABC transporter ATP-binding protein 317379 dppD 890021 dppD Helicobacter pylori J99 peptide ABC transporter ATP-binding protein NP_223006.1 316516 D 85963 CDS NP_223007.1 15611356 889335 317376..318182 1 NC_000921.1 similar to H. pylori 26695 gene HP0302; peptide ABC transporter ATP-binding protein 318182 dppF 889335 dppF Helicobacter pylori J99 peptide ABC transporter ATP-binding protein NP_223007.1 317376 D 85963 CDS NP_223008.1 15611357 889375 318202..319284 1 NC_000921.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 319284 obgE 889375 obgE Helicobacter pylori J99 GTPase ObgE NP_223008.1 318202 D 85963 CDS NP_223009.1 15611358 889081 319480..320475 1 NC_000921.1 similar to H. pylori 26695 gene HP0304; hypothetical protein 320475 889081 jhp0289 Helicobacter pylori J99 hypothetical protein NP_223009.1 319480 D 85963 CDS NP_223010.1 15611359 889357 320741..321295 1 NC_000921.1 similar to H. pylori 26695 gene HP0305; hypothetical protein 321295 889357 jhp0290 Helicobacter pylori J99 hypothetical protein NP_223010.1 320741 D 85963 CDS NP_223011.1 15611360 889367 321305..322597 1 NC_000921.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 322597 hemL 889367 hemL Helicobacter pylori J99 glutamate-1-semialdehyde aminotransferase NP_223011.1 321305 D 85963 CDS NP_223012.1 15611361 890334 322587..322865 1 NC_000921.1 similar to H. pylori 26695 gene HP0307; hypothetical protein 322865 890334 jhp0292 Helicobacter pylori J99 hypothetical protein NP_223012.1 322587 D 85963 CDS NP_223013.1 15611362 890328 322881..323285 1 NC_000921.1 similar to H. pylori 26695 gene HP0308; hypothetical protein 323285 890328 jhp0293 Helicobacter pylori J99 hypothetical protein NP_223013.1 322881 D 85963 CDS NP_223014.1 15611363 890311 323369..324253 1 NC_000921.1 similar to H. pylori 26695 gene HP0309; hypothetical protein 324253 890311 jhp0294 Helicobacter pylori J99 hypothetical protein NP_223014.1 323369 D 85963 CDS NP_223015.1 15611364 890305 324266..325147 1 NC_000921.1 similar to H. pylori 26695 gene HP0310; hypothetical protein 325147 890305 jhp0295 Helicobacter pylori J99 hypothetical protein NP_223015.1 324266 D 85963 CDS NP_223016.1 15611365 890294 325193..325561 1 NC_000921.1 similar to H. pylori 26695 gene HP0311; hypothetical protein 325561 890294 jhp0296 Helicobacter pylori J99 hypothetical protein NP_223016.1 325193 D 85963 CDS NP_223017.1 15611366 890292 325561..326526 1 NC_000921.1 similar to H. pylori 26695 gene HP0312; hypothetical protein 326526 890292 jhp0297 Helicobacter pylori J99 hypothetical protein NP_223017.1 325561 D 85963 CDS NP_223018.1 15611367 890289 complement(326532..327677) 1 NC_000921.1 similar to H. pylori 26695 gene HP0313; hypothetical protein 327677 890289 jhp0298 Helicobacter pylori J99 hypothetical protein NP_223018.1 326532 R 85963 CDS NP_223019.1 15611368 890272 complement(327878..328633) 1 NC_000921.1 similar to H. pylori 26695 gene HP0611 and HP0612; hypothetical protein 328633 890272 jhp0299 Helicobacter pylori J99 hypothetical protein NP_223019.1 327878 R 85963 CDS NP_223020.1 15611369 890254 complement(328633..329334) 1 NC_000921.1 similar to H. pylori 26695 gene HP0613; ABC transporter ATP-binding protein 329334 890254 jhp0300 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_223020.1 328633 R 85963 CDS NP_223021.1 15611370 890234 complement(329907..330662) 1 NC_000921.1 similar to H. pylori 26695 gene HP0318; hypothetical protein 330662 890234 jhp0301 Helicobacter pylori J99 hypothetical protein NP_223021.1 329907 R 85963 CDS NP_223022.1 15611371 890230 complement(330939..332564) 1 NC_000921.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 332564 argS 890230 argS Helicobacter pylori J99 arginyl-tRNA synthetase NP_223022.1 330939 R 85963 CDS NP_223023.1 15611372 889311 complement(332567..332806) 1 NC_000921.1 similar to H. pylori 26695 gene HP0320; hypothetical protein 332806 889311 jhp0303 Helicobacter pylori J99 hypothetical protein NP_223023.1 332567 R 85963 CDS NP_223024.1 15611373 890174 complement(332878..333498) 1 NC_000921.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 333498 gmk 890174 gmk Helicobacter pylori J99 guanylate kinase NP_223024.1 332878 R 85963 CDS NP_223025.1 15611374 890140 complement(333491..334996) 1 NC_000921.1 similar to H. pylori 26695 gene HP0322; poly E-rich protein 334996 890140 jhp0305 Helicobacter pylori J99 poly E-rich protein NP_223025.1 333491 R 85963 CDS NP_223026.1 15611375 889310 335138..335680 1 NC_000921.1 membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 335680 889310 jhp0306 Helicobacter pylori J99 nuclease NucT NP_223026.1 335138 D 85963 CDS NP_223027.1 15611376 890067 complement(335688..336425) 1 NC_000921.1 similar to H. pylori 26695 gene HP0324; hypothetical protein 336425 890067 jhp0307 Helicobacter pylori J99 hypothetical protein NP_223027.1 335688 R 85963 CDS NP_223028.1 15611377 890080 336559..337272 1 NC_000921.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 337272 flgH 890080 flgH Helicobacter pylori J99 flagellar basal body L-ring protein NP_223028.1 336559 D 85963 CDS NP_223029.1 15611378 889345 338845..339387 1 NC_000921.1 similar to H. pylori 26695 gene HP0327; flagellar biosynthesis protein 339387 flaG 889345 flaG Helicobacter pylori J99 flagellar biosynthesis protein NP_223029.1 338845 D 85963 CDS NP_223030.1 15611379 889374 complement(339320..340258) 1 NC_000921.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 340258 lpxK 889374 lpxK Helicobacter pylori J99 tetraacyldisaccharide 4'-kinase NP_223030.1 339320 R 85963 CDS NP_223031.1 15611380 889334 complement(340255..341037) 1 NC_000921.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 341037 nadE 889334 nadE Helicobacter pylori J99 NAD synthetase NP_223031.1 340255 R 85963 CDS NP_223032.1 15611381 889356 341286..342278 1 NC_000921.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 342278 ilvC 889356 ilvC Helicobacter pylori J99 ketol-acid reductoisomerase NP_223032.1 341286 D 85963 CDS NP_223033.1 15611382 889358 342303..343109 1 NC_000921.1 similar to H. pylori 26695 gene HP0331; cell division inhibitor 343109 minD 889358 minD Helicobacter pylori J99 cell division inhibitor NP_223033.1 342303 D 85963 CDS NP_223034.1 15611383 889371 343106..343339 1 NC_000921.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 343339 minE 889371 minE Helicobacter pylori J99 cell division topological specificity factor MinE NP_223034.1 343106 D 85963 CDS NP_223035.1 15611384 889353 343351..344151 1 NC_000921.1 similar to H. pylori 26695 gene HP0333; hypothetical protein 344151 889353 jhp0316 Helicobacter pylori J99 hypothetical protein NP_223035.1 343351 D 85963 CDS NP_223036.1 15611385 889372 344148..344552 1 NC_000921.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 344552 889372 jhp0317 Helicobacter pylori J99 Holliday junction resolvase-like protein NP_223036.1 344148 D 85963 CDS NP_223037.1 15611386 889354 344811..345566 1 NC_000921.1 hypothetical protein 345566 889354 jhp0318 Helicobacter pylori J99 hypothetical protein NP_223037.1 344811 D 85963 CDS NP_223038.1 15611387 889359 345751..346089 1 NC_000921.1 similar to H. pylori 26695 gene HP0337; hypothetical protein 346089 889359 jhp0319 Helicobacter pylori J99 hypothetical protein NP_223038.1 345751 D 85963 CDS NP_223039.1 15611388 889363 346073..346633 1 NC_000921.1 similar to H. pylori 26695 gene HP0338; hypothetical protein 346633 889363 jhp0320 Helicobacter pylori J99 hypothetical protein NP_223039.1 346073 D 85963 CDS NP_223040.1 15611389 889306 complement(346804..347685) 1 NC_000921.1 similar to H. pylori 26695 gene HP0347; hypothetical protein 347685 889306 jhp0321 Helicobacter pylori J99 hypothetical protein NP_223040.1 346804 R 85963 CDS NP_223041.1 15611390 889361 complement(347685..349235) 1 NC_000921.1 similar to H. pylori 26695 gene HP0348; single-stranded-DNA-specific exonuclease RECJ 349235 recJ 889361 recJ Helicobacter pylori J99 single-stranded-DNA-specific exonuclease RECJ NP_223041.1 347685 R 85963 CDS NP_223042.1 15611391 889305 complement(349245..350861) 1 NC_000921.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 350861 pyrG 889305 pyrG Helicobacter pylori J99 CTP synthetase NP_223042.1 349245 R 85963 CDS NP_223043.1 15611392 889330 351122..351784 1 NC_000921.1 similar to H. pylori 26695 gene HP0350; hypothetical protein 351784 889330 jhp0324 Helicobacter pylori J99 hypothetical protein NP_223043.1 351122 D 85963 CDS NP_223044.1 15611393 889326 351828..353531 1 NC_000921.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 353531 fliF 889326 fliF Helicobacter pylori J99 flagellar MS-ring protein NP_223044.1 351828 D 85963 CDS NP_223045.1 15611394 889342 353548..354579 1 NC_000921.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 354579 fliG 889342 fliG Helicobacter pylori J99 flagellar motor switch protein G NP_223045.1 353548 D 85963 CDS NP_223046.1 15611395 889325 354566..355342 1 NC_000921.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 355342 fliH 889325 fliH Helicobacter pylori J99 flagellar assembly protein H NP_223046.1 354566 D 85963 CDS NP_223047.1 15611396 890336 355339..357195 1 NC_000921.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 357195 dxs 890336 dxs Helicobacter pylori J99 1-deoxy-D-xylulose-5-phosphate synthase NP_223047.1 355339 D 85963 CDS NP_223048.1 15611397 889348 357192..359006 1 NC_000921.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 359006 lepA 889348 lepA Helicobacter pylori J99 GTP-binding protein LepA NP_223048.1 357192 D 85963 CDS NP_223049.1 15611398 889346 359021..359779 1 NC_000921.1 similar to H. pylori 26695 gene HP0356; hypothetical protein 359779 889346 jhp0330 Helicobacter pylori J99 hypothetical protein NP_223049.1 359021 D 85963 CDS NP_223050.1 15611399 889351 359722..360018 1 NC_000921.1 hypothetical protein 360018 889351 jhp0331 Helicobacter pylori J99 hypothetical protein NP_223050.1 359722 D 85963 CDS NP_223051.1 15611400 890238 360050..360310 1 NC_000921.1 hypothetical protein 360310 890238 jhp0332 Helicobacter pylori J99 hypothetical protein NP_223051.1 360050 D 85963 CDS NP_223052.1 15611401 890229 complement(360338..361147) 1 NC_000921.1 similar to H. pylori 26695 gene HP1092; flagellar basal-body rod protein 361147 flgG_1 890229 flgG_1 Helicobacter pylori J99 flagellar basal-body rod protein NP_223052.1 360338 R 85963 CDS NP_223053.1 15611402 889332 complement(361203..362516) 1 NC_000921.1 similar to H. pylori 26695 gene HP1091; alpha-ketoglutarate permease 362516 kgtP 889332 kgtP Helicobacter pylori J99 alpha-ketoglutarate permease NP_223053.1 361203 R 85963 CDS NP_223054.1 15611403 890169 complement(362902..365436) 1 NC_000921.1 similar to H. pylori 26695 gene HP1090; septum formation protein 365436 ftsK 890169 ftsK Helicobacter pylori J99 septum formation protein NP_223054.1 362902 R 85963 CDS NP_223055.1 15611404 890154 complement(365433..367769) 1 NC_000921.1 similar to H. pylori 26695 gene HP1089; hypothetical protein 367769 890154 jhp0336 Helicobacter pylori J99 hypothetical protein NP_223055.1 365433 R 85963 CDS NP_223056.1 15611405 890258 complement(367766..369691) 1 NC_000921.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 369691 tktA 890258 tktA Helicobacter pylori J99 transketolase NP_223056.1 367766 R 85963 CDS NP_223057.1 15611406 889365 complement(369738..370580) 1 NC_000921.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 370580 ribF 889365 ribF Helicobacter pylori J99 bifunctional riboflavin kinase/FMN adenylyltransferase NP_223057.1 369738 R 85963 CDS NP_223058.1 15611407 889339 complement(370546..371253) 1 NC_000921.1 similar to H. pylori 26695 gene HP1086; hemolysin 371253 hlyA 889339 hlyA Helicobacter pylori J99 hemolysin NP_223058.1 370546 R 85963 CDS NP_223059.1 15611408 889117 complement(371253..371762) 1 NC_000921.1 similar to H. pylori 26695 gene HP1085; hypothetical protein 371762 889117 jhp0340 Helicobacter pylori J99 hypothetical protein NP_223059.1 371253 R 85963 CDS NP_223060.1 15611409 889118 371835..372758 1 NC_000921.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 372758 pyrB 889118 pyrB Helicobacter pylori J99 aspartate carbamoyltransferase NP_223060.1 371835 D 85963 CDS NP_223061.1 15611410 889122 373015..374454 1 NC_000921.1 similar to H. pylori 26695 gene HP1083; hypothetical protein 374454 889122 jhp0342 Helicobacter pylori J99 hypothetical protein NP_223061.1 373015 D 85963 CDS NP_223062.1 15611411 889123 374545..376200 1 NC_000921.1 similar to H. pylori 26695 gene HP1082; multi-drug resistance protein 376200 msbA 889123 msbA Helicobacter pylori J99 multi-drug resistance protein NP_223062.1 374545 D 85963 CDS NP_223063.1 15611412 889126 376194..376817 1 NC_000921.1 similar to H. pylori 26695 gene HP1081; hypothetical protein 376817 889126 jhp0344 Helicobacter pylori J99 hypothetical protein NP_223063.1 376194 D 85963 CDS NP_223064.1 15611413 889129 376821..377390 1 NC_000921.1 similar to H. pylori 26695 gene HP1080; hypothetical protein 377390 889129 jhp0345 Helicobacter pylori J99 hypothetical protein NP_223064.1 376821 D 85963 CDS NP_223065.1 15611414 889093 377523..378668 1 NC_000921.1 similar to H. pylori 26695 gene HP1079; hypothetical protein 378668 889093 jhp0346 Helicobacter pylori J99 hypothetical protein NP_223065.1 377523 D 85963 CDS NP_223066.1 15611415 889090 378854..379357 1 NC_000921.1 similar to H. pylori 26695 gene HP1078; hypothetical protein 379357 889090 jhp0347 Helicobacter pylori J99 hypothetical protein NP_223066.1 378854 D 85963 CDS NP_223067.1 15611416 889097 379415..380410 1 NC_000921.1 similar to H. pylori 26695 gene HP1077; high-affinity nickel-transport protein 380410 nixA 889097 nixA Helicobacter pylori J99 high-affinity nickel-transport protein NP_223067.1 379415 D 85963 CDS NP_223068.1 15611417 889094 complement(380414..380935) 1 NC_000921.1 similar to H. pylori 26695 gene HP1076; hypothetical protein 380935 889094 jhp0349 Helicobacter pylori J99 hypothetical protein NP_223068.1 380414 R 85963 CDS NP_223069.1 15611418 889100 381071..382387 1 NC_000921.1 similar to H. pylori 26695 gene HP1075; hypothetical protein 382387 889100 jhp0350 Helicobacter pylori J99 hypothetical protein NP_223069.1 381071 D 85963 CDS NP_223070.1 15611419 889098 complement(382409..383227) 1 NC_000921.1 similar to H. pylori 26695 gene HP1074; hypothetical protein 383227 889098 jhp0351 Helicobacter pylori J99 hypothetical protein NP_223070.1 382409 R 85963 CDS NP_223071.1 15611420 889104 complement(383426..383626) 1 NC_000921.1 similar to H. pylori 26695 gene HP1073; copper-associated protein 383626 copP 889104 copP Helicobacter pylori J99 copper-associated protein NP_223071.1 383426 R 85963 CDS NP_223072.1 15611421 889106 complement(383627..385864) 1 NC_000921.1 similar to H. pylori 26695 gene HP1072; copper-transporting P-type ATPase 385864 copA 889106 copA Helicobacter pylori J99 copper-transporting P-type ATPase NP_223072.1 383627 R 85963 CDS NP_223073.1 15611422 889108 complement(385861..386574) 1 NC_000921.1 similar to H. pylori 26695 gene HP1071; phosphatidylserine synthase 386574 pssA 889108 pssA Helicobacter pylori J99 phosphatidylserine synthase NP_223073.1 385861 R 85963 CDS NP_223074.1 15611423 889114 complement(386564..386824) 1 NC_000921.1 similar to H. pylori 26695 gene HP1070; hypothetical protein 386824 889114 jhp0355 Helicobacter pylori J99 hypothetical protein NP_223074.1 386564 R 85963 CDS NP_223075.1 15611424 889116 complement(386827..388725) 1 NC_000921.1 similar to H. pylori 26695 gene HP1069; ATP-dependent zinc metallopeptidase 388725 ftsH_2 889116 ftsH_2 Helicobacter pylori J99 ATP-dependent zinc metallopeptidase NP_223075.1 386827 R 85963 CDS NP_223076.1 15611425 888979 complement(388734..389723) 1 NC_000921.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 389723 prmA 888979 prmA Helicobacter pylori J99 ribosomal protein L11 methyltransferase NP_223076.1 388734 R 85963 CDS NP_223077.1 15611426 889086 complement(389724..390098) 1 NC_000921.1 similar to H. pylori 26695 gene HP1067; response regulator 390098 cheY 889086 cheY Helicobacter pylori J99 response regulator NP_223077.1 389724 R 85963 CDS NP_223078.1 15611427 888980 390392..390994 1 NC_000921.1 similar to H. pylori 26695 gene HP1066; hypothetical protein 390994 888980 jhp0359 Helicobacter pylori J99 hypothetical protein NP_223078.1 390392 D 85963 CDS NP_223079.1 15611428 888987 complement(391140..391547) 1 NC_000921.1 similar to H. pylori 26695 gene HP1065; hypothetical protein 391547 888987 jhp0360 Helicobacter pylori J99 hypothetical protein NP_223079.1 391140 R 85963 CDS NP_223080.1 15611429 889069 complement(391550..391843) 1 NC_000921.1 similar to H. pylori 26695 gene HP1064; hypothetical protein 391843 889069 jhp0361 Helicobacter pylori J99 hypothetical protein NP_223080.1 391550 R 85963 CDS NP_223081.1 15611430 889261 complement(391786..392322) 1 NC_000921.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 392322 gidB 889261 gidB Helicobacter pylori J99 16S rRNA methyltransferase GidB NP_223081.1 391786 R 85963 CDS NP_223082.1 15611431 889259 complement(392319..393356) 1 NC_000921.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 393356 queA 889259 queA Helicobacter pylori J99 S-adenosylmethionine:tRNA ribosyltransferase-isomerase NP_223082.1 392319 R 85963 CDS NP_223083.1 15611432 889360 complement(393357..394106) 1 NC_000921.1 similar to H. pylori 26695 gene HP1061; hypothetical protein 394106 889360 jhp0364 Helicobacter pylori J99 hypothetical protein NP_223083.1 393357 R 85963 CDS NP_223084.1 15611433 889275 complement(394099..394581) 1 NC_000921.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 394581 889275 jhp0365 Helicobacter pylori J99 sec-independent translocase NP_223084.1 394099 R 85963 CDS NP_223085.1 15611434 889058 complement(394648..395658) 1 NC_000921.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 395658 ruvB 889058 ruvB Helicobacter pylori J99 Holliday junction DNA helicase RuvB NP_223085.1 394648 R 85963 CDS NP_223086.1 15611435 889082 complement(395659..396471) 1 NC_000921.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 396471 panB 889082 panB Helicobacter pylori J99 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_223086.1 395659 R 85963 CDS NP_223087.1 15611436 889059 396622..397344 1 NC_000921.1 similar to H. pylori 26695 gene HP1057; hypothetical protein 397344 889059 jhp0368 Helicobacter pylori J99 hypothetical protein NP_223087.1 396622 D 85963 CDS NP_223088.1 15611437 889065 397322..398191 1 NC_000921.1 similar to H. pylori 26695 gene HP1056; hypothetical protein 398191 889065 jhp0369 Helicobacter pylori J99 hypothetical protein NP_223088.1 397322 D 85963 CDS NP_223089.1 15611438 888977 398203..399144 1 NC_000921.1 similar to H. pylori 26695 gene HP1055; hypothetical protein 399144 888977 jhp0370 Helicobacter pylori J99 hypothetical protein NP_223089.1 398203 D 85963 CDS NP_223090.1 15611439 889083 399154..400476 1 NC_000921.1 similar to H. pylori 26695 gene HP1054; hypothetical protein 400476 889083 jhp0371 Helicobacter pylori J99 hypothetical protein NP_223090.1 399154 D 85963 CDS NP_223091.1 15611440 888971 400479..401063 1 NC_000921.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 401063 minC 888971 minC Helicobacter pylori J99 septum formation inhibitor NP_223091.1 400479 D 85963 CDS NP_223092.1 15611441 889055 401060..401947 1 NC_000921.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 401947 lpxC 889055 lpxC Helicobacter pylori J99 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_223092.1 401060 D 85963 CDS NP_223093.1 15611442 889036 401969..402466 1 NC_000921.1 similar to H. pylori 26695 gene HP1051; hypothetical protein 402466 889036 jhp0374 Helicobacter pylori J99 hypothetical protein NP_223093.1 401969 D 85963 CDS NP_223094.1 15611443 889035 402520..403401 1 NC_000921.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 403401 thrB 889035 thrB Helicobacter pylori J99 homoserine kinase NP_223094.1 402520 D 85963 CDS NP_223095.1 15611444 889031 403373..403642 1 NC_000921.1 similar to H. pylori 26695 gene HP1049; hypothetical protein 403642 889031 jhp0376 Helicobacter pylori J99 hypothetical protein NP_223095.1 403373 D 85963 CDS NP_223096.1 15611445 889030 403639..406488 1 NC_000921.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 406488 infB 889030 infB Helicobacter pylori J99 translation initiation factor IF-2 NP_223096.1 403639 D 85963 CDS NP_223097.1 15611446 889024 406488..406823 1 NC_000921.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 406823 rbfA 889024 rbfA Helicobacter pylori J99 ribosome-binding factor A NP_223097.1 406488 D 85963 CDS NP_223098.1 15611447 889087 406816..407256 1 NC_000921.1 similar to H. pylori 26695 gene HP1046; hypothetical protein 407256 889087 jhp0379 Helicobacter pylori J99 hypothetical protein NP_223098.1 406816 D 85963 CDS NP_223099.1 15611448 889130 407417..408529 1 NC_000921.1 similar to H. pylori 26695 gene HP1044; hypothetical protein 408529 889130 jhp0380 Helicobacter pylori J99 hypothetical protein NP_223099.1 407417 D 85963 CDS NP_223100.1 15611449 889131 408882..409553 1 NC_000921.1 similar to H. pylori 26695 gene HP1043; transcriptional regulator 409553 889131 jhp0381 Helicobacter pylori J99 transcriptional regulator NP_223100.1 408882 D 85963 CDS NP_223101.1 15611450 889132 complement(410346..411389) 1 NC_000921.1 similar to H. pylori 26695 gene HP1042; hypothetical protein 411389 889132 jhp0382 Helicobacter pylori J99 hypothetical protein NP_223101.1 410346 R 85963 CDS NP_223102.1 15611451 889133 complement(411423..413624) 1 NC_000921.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 413624 flhA 889133 flhA Helicobacter pylori J99 flagellar biosynthesis protein FlhA NP_223102.1 411423 R 85963 CDS NP_223103.1 15611452 889136 413760..414032 1 NC_000921.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 414032 rpsO 889136 rpsO Helicobacter pylori J99 30S ribosomal protein S15 NP_223103.1 413760 D 85963 CDS NP_223104.1 15611453 889141 414088..415377 1 NC_000921.1 similar to H. pylori 26695 gene HP1039; hypothetical protein 415377 889141 jhp0385 Helicobacter pylori J99 hypothetical protein NP_223104.1 414088 D 85963 CDS NP_223105.1 15611454 889144 415490..416002 1 NC_000921.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 416002 aroD 889144 aroD Helicobacter pylori J99 3-dehydroquinate dehydratase NP_223105.1 415490 D 85963 CDS NP_223106.1 15611455 889146 416015..417088 1 NC_000921.1 similar to H. pylori 26695 gene HP1037; proline peptidase 417088 pepQ 889146 pepQ Helicobacter pylori J99 proline peptidase NP_223106.1 416015 D 85963 CDS NP_223107.1 15611456 889149 417085..417576 1 NC_000921.1 similar to H. pylori 26695 gene HP1036; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 417576 folK 889149 folK Helicobacter pylori J99 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase NP_223107.1 417085 D 85963 CDS NP_223108.1 15611457 889152 417573..418940 1 NC_000921.1 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 418940 flhF 889152 flhF Helicobacter pylori J99 flagellar biosynthesis regulator FlhF NP_223108.1 417573 D 85963 CDS NP_223109.1 15611458 889173 418937..419821 1 NC_000921.1 similar to H. pylori 26695 gene HP1034; hypothetical protein 419821 889173 jhp0390 Helicobacter pylori J99 hypothetical protein NP_223109.1 418937 D 85963 CDS NP_223110.1 15611459 889176 complement(419834..420109) 1 NC_000921.1 similar to H. pylori 26695 gene HP1033; hypothetical protein 420109 889176 jhp0391 Helicobacter pylori J99 hypothetical protein NP_223110.1 419834 R 85963 CDS NP_223111.1 15611460 889178 420118..420885 1 NC_000921.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 420885 fliA 889178 fliA Helicobacter pylori J99 flagellar biosynthesis sigma factor NP_223111.1 420118 D 85963 CDS NP_223112.1 15611461 889210 420878..421942 1 NC_000921.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 421942 fliM 889210 fliM Helicobacter pylori J99 flagellar motor switch protein FliM NP_223112.1 420878 D 85963 CDS NP_223113.1 15611462 889271 421946..422803 1 NC_000921.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 422803 889271 jhp0394 Helicobacter pylori J99 flagellar motor switch protein FliY NP_223113.1 421946 D 85963 CDS NP_223114.1 15611463 889272 422833..423369 1 NC_000921.1 similar to H. pylori 26695 gene HP1029; hypothetical protein 423369 889272 jhp0395 Helicobacter pylori J99 hypothetical protein NP_223114.1 422833 D 85963 CDS NP_223115.1 15611464 889273 423366..423869 1 NC_000921.1 similar to H. pylori 26695 gene HP1028; hypothetical protein 423869 889273 jhp0396 Helicobacter pylori J99 hypothetical protein NP_223115.1 423366 D 85963 CDS NP_223116.1 15611465 889274 complement(423889..424341) 1 NC_000921.1 similar to H. pylori 26695 gene HP1027; ferric uptake regulation protein 424341 fur 889274 fur Helicobacter pylori J99 ferric uptake regulation protein NP_223116.1 423889 R 85963 CDS NP_223117.1 15611466 889137 complement(424501..425676) 1 NC_000921.1 similar to H. pylori 26695 gene HP1026; recombination factor protein RarA 425676 889137 jhp0398 Helicobacter pylori J99 recombination factor protein RarA NP_223117.1 424501 R 85963 CDS NP_223118.1 15611467 889186 complement(425673..426044) 1 NC_000921.1 similar to H. pylori 26695 gene HP1025; transcriptional regulator 426044 889186 jhp0399 Helicobacter pylori J99 transcriptional regulator NP_223118.1 425673 R 85963 CDS NP_223119.1 15611468 889187 complement(426054..426920) 1 NC_000921.1 similar to H. pylori 26695 gene HP1024; co-chaperone with DnaK 426920 dnaJ_1 889187 dnaJ_1 Helicobacter pylori J99 co-chaperone with DnaK NP_223119.1 426054 R 85963 CDS NP_223120.1 15611469 888975 427088..428338 1 NC_000921.1 similar to H. pylori 26695 gene HP1023; hypothetical protein 428338 888975 jhp0401 Helicobacter pylori J99 hypothetical protein NP_223120.1 427088 D 85963 CDS NP_223121.1 15611470 889229 complement(428582..429448) 1 NC_000921.1 similar to H. pylori 26695 gene HP1022; hypothetical protein 429448 889229 jhp0402 Helicobacter pylori J99 hypothetical protein NP_223121.1 428582 R 85963 CDS NP_223122.1 15611471 889215 complement(429669..430565) 1 NC_000921.1 similar to H. pylori 26695 gene HP1021; response regulator 430565 889215 jhp0403 Helicobacter pylori J99 response regulator NP_223122.1 429669 R 85963 CDS NP_223123.1 15611472 889224 complement(430587..431816) 1 NC_000921.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 431816 ispDF 889224 ispDF Helicobacter pylori J99 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_223123.1 430587 R 85963 CDS NP_223124.1 15611473 889218 complement(431838..433268) 1 NC_000921.1 similar to H. pylori 26695 gene HP1019; protease Do 433268 htrA 889218 htrA Helicobacter pylori J99 protease Do NP_223124.1 431838 R 85963 CDS NP_223125.1 15611474 889205 complement(433313..434740) 1 NC_000921.1 similar to H. pylori 26695 gene HP1017; amino acid permease 434740 889205 jhp0406 Helicobacter pylori J99 amino acid permease NP_223125.1 433313 R 85963 CDS NP_223126.1 15611475 889203 complement(434936..435538) 1 NC_000921.1 similar to H. pylori 26695 gene HP1016; phosphatidylglycerophosphate synthase 435538 pgsA 889203 pgsA Helicobacter pylori J99 phosphatidylglycerophosphate synthase NP_223126.1 434936 R 85963 CDS NP_223127.1 15611476 889198 complement(435472..436080) 1 NC_000921.1 similar to H. pylori 26695 gene HP1015; hypothetical protein 436080 889198 jhp0408 Helicobacter pylori J99 hypothetical protein NP_223127.1 435472 R 85963 CDS NP_223128.1 15611477 889197 complement(436090..436878) 1 NC_000921.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 436878 889197 jhp0409 Helicobacter pylori J99 7-alpha-hydroxysteroid dehydrogenase NP_223128.1 436090 R 85963 CDS NP_223129.1 15611478 889107 complement(436875..437777) 1 NC_000921.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 437777 dapA 889107 dapA Helicobacter pylori J99 dihydrodipicolinate synthase NP_223129.1 436875 R 85963 CDS NP_223130.1 15611479 889194 complement(437791..439122) 1 NC_000921.1 similar to H. pylori 26695 gene HP1012; zinc protease 439122 889194 jhp0411 Helicobacter pylori J99 zinc protease NP_223130.1 437791 R 85963 CDS NP_223131.1 15611480 889119 complement(439119..440174) 1 NC_000921.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 440174 pyrD 889119 pyrD Helicobacter pylori J99 dihydroorotate dehydrogenase 2 NP_223131.1 439119 R 85963 CDS NP_223132.1 15611481 889193 complement(440213..442240) 1 NC_000921.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 442240 ppk 889193 ppk Helicobacter pylori J99 polyphosphate kinase NP_223132.1 440213 R 85963 CDS NP_223133.1 15611482 889192 complement(442888..444117) 1 NC_000921.1 type I restriction enzyme specificity subunit 444117 hsdS_1a 889192 hsdS_1a Helicobacter pylori J99 type I restriction enzyme specificity subunit NP_223133.1 442888 R 85963 CDS NP_223134.1 15611483 889191 complement(444110..445741) 1 NC_000921.1 similar to H. pylori 26695 gene HP0463; type I restriction enzyme modification subunit 445741 hsdM_1 889191 hsdM_1 Helicobacter pylori J99 type I restriction enzyme modification subunit NP_223134.1 444110 R 85963 CDS NP_223135.1 15611484 889185 complement(448924..450819) 1 NC_000921.1 similar to H. pylori 26695 gene HP0465; hypothetical protein 450819 889185 jhp0417 Helicobacter pylori J99 hypothetical protein NP_223135.1 448924 R 85963 CDS NP_223136.1 15611485 889181 complement(450844..451611) 1 NC_000921.1 similar to H. pylori 26695 gene HP0466; hypothetical protein 451611 889181 jhp0418 Helicobacter pylori J99 hypothetical protein NP_223136.1 450844 R 85963 CDS NP_223137.1 15611486 889051 complement(451621..451968) 1 NC_000921.1 similar to H. pylori 26695 gene HP0467; hypothetical protein 451968 889051 jhp0419 Helicobacter pylori J99 hypothetical protein NP_223137.1 451621 R 85963 CDS NP_223138.1 15611487 889050 complement(451937..453424) 1 NC_000921.1 similar to H. pylori 26695 gene HP0468; hypothetical protein 453424 889050 jhp0420 Helicobacter pylori J99 hypothetical protein NP_223138.1 451937 R 85963 CDS NP_223139.1 15611488 889040 complement(453436..453924) 1 NC_000921.1 similar to H. pylori 26695 gene HP0469; hypothetical protein 453924 889040 jhp0421 Helicobacter pylori J99 hypothetical protein NP_223139.1 453436 R 85963 CDS NP_223140.1 15611489 889029 complement(453909..455645) 1 NC_000921.1 similar to H. pylori 26695 gene HP0470; oligopeptidase 455645 pepF 889029 pepF Helicobacter pylori J99 oligopeptidase NP_223140.1 453909 R 85963 CDS NP_223141.1 15611490 889027 complement(455743..456993) 1 NC_000921.1 similar to H. pylori 26695 gene HP0471; glutathione-regulated potassium-efflux system protein 456993 kefB 889027 kefB Helicobacter pylori J99 glutathione-regulated potassium-efflux system protein NP_223141.1 455743 R 85963 CDS NP_223142.1 15611491 888982 complement(457312..457872) 1 NC_000921.1 similar to H. pylori 26695 gene HP0472; hypothetical protein 457872 888982 jhp0424 Helicobacter pylori J99 hypothetical protein NP_223142.1 457312 R 85963 CDS NP_223143.1 15611492 888973 458097..458837 1 NC_000921.1 similar to H. pylori 26695 gene HP0473; molybdate ABC transporter periplasmic-binding protein 458837 modA 888973 modA Helicobacter pylori J99 molybdate ABC transporter periplasmic-binding protein NP_223143.1 458097 D 85963 CDS NP_223144.1 15611493 888970 458859..459533 1 NC_000921.1 similar to H. pylori 26695 gene HP0474; molybdate ABC transporter permease 459533 modB 888970 modB Helicobacter pylori J99 molybdate ABC transporter permease NP_223144.1 458859 D 85963 CDS NP_223145.1 15611494 888996 459530..460327 1 NC_000921.1 similar to H. pylori 26695 gene HP0475; molybdate ABC transporter ATP-binding protein 460327 modC 888996 modC Helicobacter pylori J99 molybdate ABC transporter ATP-binding protein NP_223145.1 459530 D 85963 CDS NP_223146.1 15611495 888993 complement(460444..461835) 1 NC_000921.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 461835 gltX 888993 gltX Helicobacter pylori J99 glutamyl-tRNA synthetase NP_223146.1 460444 R 85963 CDS NP_223147.1 15611496 889014 461953..463068 1 NC_000921.1 similar to H. pylori 26695 gene HP0477; hypothetical protein 463068 889014 jhp0429 Helicobacter pylori J99 hypothetical protein NP_223147.1 461953 D 85963 CDS NP_223148.1 15611497 889039 463077..464714 1 NC_000921.1 similar to H. pylori 26695 gene HP0478; type II DNA modification (methyltransferase 464714 889039 jhp0430 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_223148.1 463077 D 85963 CDS NP_223149.1 15611498 889219 464680..465528 1 NC_000921.1 similar to H. pylori 26695 gene HP0479; hypothetical protein 465528 889219 jhp0431 Helicobacter pylori J99 hypothetical protein NP_223149.1 464680 D 85963 CDS NP_223150.1 15611499 889019 465574..467373 1 NC_000921.1 similar to H. pylori 26695 gene HP0480; hypothetical protein 467373 889019 jhp0432 Helicobacter pylori J99 hypothetical protein NP_223150.1 465574 D 85963 CDS NP_223151.1 15611500 889021 467389..468318 1 NC_000921.1 similar to H. pylori 26695 gene HP0481; type II DNA modification enzyme 468318 889021 jhp0433 Helicobacter pylori J99 type II DNA modification enzyme NP_223151.1 467389 D 85963 CDS NP_223152.1 15611501 889245 468321..468848 1 NC_000921.1 similar to H. pylori 26695 gene HP0482; hypothetical protein 468848 889245 jhp0434 Helicobacter pylori J99 hypothetical protein NP_223152.1 468321 D 85963 CDS NP_223153.1 15611502 889077 469030..470085 1 NC_000921.1 similar to H. pylori 26695 gene HP0483; type II DNA modification (methyltransferase 470085 889077 jhp0435 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_223153.1 469030 D 85963 CDS NP_223154.1 15611503 889047 470276..470830 1 NC_000921.1 similar to H. pylori 26695 gene HP0484; hypothetical protein 470830 889047 jhp0436 Helicobacter pylori J99 hypothetical protein NP_223154.1 470276 D 85963 CDS NP_223155.1 15611504 889216 complement(471069..472013) 1 NC_000921.1 similar to H. pylori 26695 gene HP0485; hypothetical protein 472013 889216 jhp0437 Helicobacter pylori J99 hypothetical protein NP_223155.1 471069 R 85963 CDS NP_223156.1 15611505 889042 472290..473876 1 NC_000921.1 similar to H. pylori 26695 gene HP0486; hypothetical protein 473876 889042 jhp0438 Helicobacter pylori J99 hypothetical protein NP_223156.1 472290 D 85963 CDS NP_223157.1 15611506 889032 473948..475345 1 NC_000921.1 similar to H. pylori 26695 gene HP0487; hypothetical protein 475345 889032 jhp0439 Helicobacter pylori J99 hypothetical protein NP_223157.1 473948 D 85963 CDS NP_223158.1 15611507 889079 475860..478598 1 NC_000921.1 similar to H. pylori 26695 gene HP0488; hypothetical protein 478598 889079 jhp0440 Helicobacter pylori J99 hypothetical protein NP_223158.1 475860 D 85963 CDS NP_223159.1 15611508 889044 478667..479212 1 NC_000921.1 similar to H. pylori 26695 gene HP0489; hypothetical protein 479212 889044 jhp0441 Helicobacter pylori J99 hypothetical protein NP_223159.1 478667 D 85963 CDS NP_223160.1 15611509 889214 complement(479452..480588) 1 NC_000921.1 similar to H. pylori 26695 gene HP0490; potassium channel protein 480588 889214 jhp0442 Helicobacter pylori J99 potassium channel protein NP_223160.1 479452 R 85963 CDS NP_223161.1 15611510 889046 complement(480775..480963) 1 NC_000921.1 required for 70S ribosome assembly; 50S ribosomal protein L28 480963 rpmB 889046 rpmB Helicobacter pylori J99 50S ribosomal protein L28 NP_223161.1 480775 R 85963 CDS NP_223162.1 15611511 889171 complement(481063..481911) 1 NC_000921.1 similar to H. pylori 26695 gene HP0492; paralog of HpaA 481911 889171 jhp0444 Helicobacter pylori J99 paralog of HpaA NP_223162.1 481063 R 85963 CDS NP_223163.1 15611512 889041 482029..483090 1 NC_000921.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 483090 mraY 889041 mraY Helicobacter pylori J99 phospho-N-acetylmuramoyl-pentapeptide- transferase NP_223163.1 482029 D 85963 CDS NP_223164.1 15611513 889170 483092..484360 1 NC_000921.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 484360 murD 889170 murD Helicobacter pylori J99 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_223164.1 483092 D 85963 CDS NP_223165.1 15611514 889052 complement(484357..484617) 1 NC_000921.1 similar to H. pylori 26695 gene HP0495; hypothetical protein 484617 889052 jhp0447 Helicobacter pylori J99 hypothetical protein NP_223165.1 484357 R 85963 CDS NP_223166.1 15611515 889175 complement(484607..485008) 1 NC_000921.1 similar to H. pylori 26695 gene HP0496; hypothetical protein 485008 889175 jhp0448 Helicobacter pylori J99 hypothetical protein NP_223166.1 484607 R 85963 CDS NP_223167.1 15611516 889053 485240..486568 1 NC_000921.1 similar to H. pylori 26695 gene HP0497; transporter 486568 889053 jhp0449 Helicobacter pylori J99 transporter NP_223167.1 485240 D 85963 CDS NP_223168.1 15611517 889166 486579..487907 1 NC_000921.1 similar to H. pylori 26695 gene HP0498; transporter 487907 889166 jhp0450 Helicobacter pylori J99 transporter NP_223168.1 486579 D 85963 CDS NP_223169.1 15611518 889048 487922..488989 1 NC_000921.1 similar to H. pylori 26695 gene HP0499; phospholipase A1 488989 pldA 889048 pldA Helicobacter pylori J99 phospholipase A1 NP_223169.1 487922 D 85963 CDS NP_223170.1 15611519 889001 489047..490171 1 NC_000921.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 490171 dnaN 889001 dnaN Helicobacter pylori J99 DNA polymerase III subunit beta NP_223170.1 489047 D 85963 CDS NP_223171.1 15611520 889037 490184..492505 1 NC_000921.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 492505 gyrB 889037 gyrB Helicobacter pylori J99 DNA gyrase subunit B NP_223171.1 490184 D 85963 CDS NP_223172.1 15611521 889078 492512..493543 1 NC_000921.1 similar to H. pylori 26695 gene HP0502 and HP0503; hypothetical protein 493543 889078 jhp0454 Helicobacter pylori J99 hypothetical protein NP_223172.1 492512 D 85963 CDS NP_223173.1 15611522 889016 493530..494285 1 NC_000921.1 similar to H. pylori 26695 gene HP0504 and HP0505; hypothetical protein 494285 889016 jhp0455 Helicobacter pylori J99 hypothetical protein NP_223173.1 493530 D 85963 CDS NP_223174.1 15611523 889015 494500..495720 1 NC_000921.1 similar to H. pylori 26695 gene HP0506; hypothetical protein 495720 889015 jhp0456 Helicobacter pylori J99 hypothetical protein NP_223174.1 494500 D 85963 CDS NP_223175.1 15611524 889061 495720..496358 1 NC_000921.1 similar to H. pylori 26695 gene HP0507; hypothetical protein 496358 889061 jhp0457 Helicobacter pylori J99 hypothetical protein NP_223175.1 495720 D 85963 CDS NP_223176.1 15611525 889006 496369..497721 1 NC_000921.1 similar to H. pylori 26695 gene HP0508; hypothetical protein 497721 889006 jhp0458 Helicobacter pylori J99 hypothetical protein NP_223176.1 496369 D 85963 CDS NP_223177.1 15611526 889043 497726..499105 1 NC_000921.1 similar to H. pylori 26695 gene HP0509; glycolate oxidase 499105 glcD 889043 glcD Helicobacter pylori J99 glycolate oxidase NP_223177.1 497726 D 85963 CDS NP_223178.1 15611527 888994 499128..499892 1 NC_000921.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 499892 dapB 888994 dapB Helicobacter pylori J99 dihydrodipicolinate reductase NP_223178.1 499128 D 85963 CDS NP_223179.1 15611528 889208 complement(501230..502675) 1 NC_000921.1 similar to H. pylori 26695 gene HP0512; glutamine synthetase 502675 glnA 889208 glnA Helicobacter pylori J99 glutamine synthetase NP_223179.1 501230 R 85963 CDS NP_223180.1 15611529 889200 502813..504933 1 NC_000921.1 similar to H. pylori 26695 gene HP0513; hypothetical protein 504933 889200 jhp0462 Helicobacter pylori J99 hypothetical protein NP_223180.1 502813 D 85963 CDS NP_223181.1 15611530 889188 504996..505445 1 NC_000921.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 505445 rplI 889188 rplI Helicobacter pylori J99 50S ribosomal protein L9 NP_223181.1 504996 D 85963 CDS NP_223182.1 15611531 889221 505449..505991 1 NC_000921.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 505991 hslV 889221 hslV Helicobacter pylori J99 ATP-dependent protease peptidase subunit NP_223182.1 505449 D 85963 CDS NP_223183.1 15611532 889220 505991..507322 1 NC_000921.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 507322 hslU 889220 hslU Helicobacter pylori J99 ATP-dependent protease ATP-binding subunit HslU NP_223183.1 505991 D 85963 CDS NP_223184.1 15611533 889212 507322..508227 1 NC_000921.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 508227 era 889212 era Helicobacter pylori J99 GTP-binding protein Era NP_223184.1 507322 D 85963 CDS NP_223185.1 15611534 889226 508224..509216 1 NC_000921.1 similar to H. pylori 26695 gene HP0518; hypothetical protein 509216 889226 jhp0467 Helicobacter pylori J99 hypothetical protein NP_223185.1 508224 D 85963 CDS NP_223186.1 15611535 889225 complement(509304..510155) 1 NC_000921.1 similar to H. pylori 26695 gene HP0519; hypothetical protein 510155 889225 jhp0468 Helicobacter pylori J99 hypothetical protein NP_223186.1 509304 R 85963 CDS NP_223187.1 15611536 889223 510500..510847 1 NC_000921.1 similar to H. pylori 26695 gene HP0520; cag island protein 510847 orf6 889223 orf6 Helicobacter pylori J99 cag island protein NP_223187.1 510500 D 85963 CDS NP_223188.1 15611537 889232 510990..511649 1 NC_000921.1 similar to H. pylori 26695 gene HP0521; cag island protein 511649 orf7 889232 orf7 Helicobacter pylori J99 cag island protein NP_223188.1 510990 D 85963 CDS NP_223189.1 15611538 889230 511642..513087 1 NC_000921.1 similar to H. pylori 26695 gene HP0522; cag island protein 513087 orf8 889230 orf8 Helicobacter pylori J99 cag island protein NP_223189.1 511642 D 85963 CDS NP_223190.1 15611539 889228 513097..513606 1 NC_000921.1 similar to H. pylori 26695 gene HP0523; cag island protein 513606 orf9 889228 orf9 Helicobacter pylori J99 cag island protein NP_223190.1 513097 D 85963 CDS NP_223191.1 15611540 889145 complement(514088..516334) 1 NC_000921.1 similar to H. pylori 26695 gene HP0524; cag island protein, DNA transfer protein 516334 virD4 889145 virD4 Helicobacter pylori J99 cag island protein, DNA transfer protein NP_223191.1 514088 R 85963 CDS NP_223192.1 15611541 889095 complement(516343..517335) 1 NC_000921.1 similar to H. pylori 26695 gene HP0525; cag island protein, DNA transfer protein 517335 virB11_1 889095 virB11_1 Helicobacter pylori J99 cag island protein, DNA transfer protein NP_223192.1 516343 R 85963 CDS NP_223193.1 15611542 889246 complement(517340..517939) 1 NC_000921.1 similar to H. pylori 26695 gene HP0526; cag island protein 517939 orf12 889246 orf12 Helicobacter pylori J99 cag island protein NP_223193.1 517340 R 85963 CDS NP_223194.1 15611543 889142 complement(518074..523533) 1 NC_000921.1 similar to H. pylori 26695 gene HP0527; cag island protein 523533 orf13/14 889142 orf13/14 Helicobacter pylori J99 cag island protein NP_223194.1 518074 R 85963 CDS NP_223195.1 15611544 889138 complement(523548..525116) 1 NC_000921.1 similar to H. pylori 26695 gene HP0528; cag island protein 525116 orf15 889138 orf15 Helicobacter pylori J99 cag island protein NP_223195.1 523548 R 85963 CDS NP_223196.1 15611545 889143 complement(525169..526776) 1 NC_000921.1 similar to H. pylori 26695 gene HP0529; cag island protein 526776 orf16 889143 orf16 Helicobacter pylori J99 cag island protein NP_223196.1 525169 R 85963 CDS NP_223197.1 15611546 889238 complement(526781..527539) 1 NC_000921.1 similar to H. pylori 26695 gene HP0530; cag island protein 527539 orf17 889238 orf17 Helicobacter pylori J99 cag island protein NP_223197.1 526781 R 85963 CDS NP_223198.1 15611547 889233 527921..528577 1 NC_000921.1 similar to H. pylori 26695 gene HP0531; cag island protein 528577 orf18 889233 orf18 Helicobacter pylori J99 cag island protein NP_223198.1 527921 D 85963 CDS NP_223199.1 15611548 889235 528613..529455 1 NC_000921.1 similar to H. pylori 26695 gene HP0532; cag island protein 529455 cagT 889235 cagT Helicobacter pylori J99 cag island protein NP_223199.1 528613 D 85963 CDS NP_223200.1 15611549 888988 complement(529660..530259) 1 NC_000921.1 similar to H. pylori 26695 gene HP0534; cag island protein 530259 cagS 888988 cagS Helicobacter pylori J99 cag island protein NP_223200.1 529660 R 85963 CDS NP_223201.1 15611550 889234 complement(530698..531078) 1 NC_000921.1 similar to H. pylori 26695 gene HP0535; cag island protein 531078 cagQ 889234 cagQ Helicobacter pylori J99 cag island protein NP_223201.1 530698 R 85963 CDS NP_223202.1 15611551 889236 complement(531505..531849) 1 NC_000921.1 similar to H. pylori 26695 gene HP0536; cag island protein 531849 cagP 889236 cagP Helicobacter pylori J99 cag island protein NP_223202.1 531505 R 85963 CDS NP_223203.1 15611552 889009 532464..533594 1 NC_000921.1 similar to H. pylori 26695 gene HP0537; cag island protein 533594 cagM 889009 cagM Helicobacter pylori J99 cag island protein NP_223203.1 532464 D 85963 CDS NP_223204.1 15611553 889196 533609..534529 1 NC_000921.1 similar to H. pylori 26695 gene HP0538; cag island protein 534529 cagN 889196 cagN Helicobacter pylori J99 cag island protein NP_223204.1 533609 D 85963 CDS NP_223205.1 15611554 888972 complement(534611..535324) 1 NC_000921.1 similar to H. pylori 26695 gene HP0539; cag island protein 535324 cagL 888972 cagL Helicobacter pylori J99 cag island protein NP_223205.1 534611 R 85963 CDS NP_223206.1 15611555 889182 complement(535321..536466) 1 NC_000921.1 similar to H. pylori 26695 gene HP0540; cag island protein 536466 cagI 889182 cagI Helicobacter pylori J99 cag island protein NP_223206.1 535321 R 85963 CDS NP_223207.1 15611556 888978 complement(536477..537589) 1 NC_000921.1 similar to H. pylori 26695 gene HP0541; cag island protein 537589 cagH 888978 cagH Helicobacter pylori J99 cag island protein NP_223207.1 536477 R 85963 CDS NP_223208.1 15611557 889000 complement(537606..538034) 1 NC_000921.1 similar to H. pylori 26695 gene HP0542; cag island protein 538034 cagG 889000 cagG Helicobacter pylori J99 cag island protein NP_223208.1 537606 R 85963 CDS NP_223209.1 15611558 889180 complement(538089..538895) 1 NC_000921.1 similar to H. pylori 26695 gene HP0543; cag island protein 538895 cagF 889180 cagF Helicobacter pylori J99 cag island protein NP_223209.1 538089 R 85963 CDS NP_223210.1 15611559 888976 complement(538897..541848) 1 NC_000921.1 similar to H. pylori 26695 gene HP0544; DNA transfer protein 541848 cagE 888976 cagE Helicobacter pylori J99 DNA transfer protein NP_223210.1 538897 R 85963 CDS NP_223211.1 15611560 889045 complement(541857..542483) 1 NC_000921.1 similar to H. pylori 26695 gene HP0545; cag island protein 542483 cagD 889045 cagD Helicobacter pylori J99 cag island protein NP_223211.1 541857 R 85963 CDS NP_223212.1 15611561 889049 complement(542485..542832) 1 NC_000921.1 similar to H. pylori 26695 gene HP0546; cag island protein 542832 cagC 889049 cagC Helicobacter pylori J99 cag island protein NP_223212.1 542485 R 85963 CDS NP_223213.1 15611562 889201 543605..547108 1 NC_000921.1 similar to H. pylori 26695 gene HP0547; cag island protein, cytotoxicity associated immunodominant antigen 547108 cagA 889201 cagA Helicobacter pylori J99 cag island protein, cytotoxicity associated immunodominant antigen NP_223213.1 543605 D 85963 CDS NP_223214.1 15611563 889183 complement(547927..548694) 1 NC_000921.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 548694 murI 889183 murI Helicobacter pylori J99 glutamate racemase NP_223214.1 547927 R 85963 CDS NP_223215.1 15611564 889207 complement(548734..550050) 1 NC_000921.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 550050 rho 889207 rho Helicobacter pylori J99 transcription termination factor Rho NP_223215.1 548734 R 85963 CDS NP_223216.1 15611565 889159 550315..550518 1 NC_000921.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 550518 rpmE 889159 rpmE Helicobacter pylori J99 50S ribosomal protein L31 NP_223216.1 550315 D 85963 CDS NP_223217.1 15611566 889204 550542..551411 1 NC_000921.1 similar to H. pylori 26695 gene HP0552; hypothetical protein 551411 889204 jhp0499 Helicobacter pylori J99 hypothetical protein NP_223217.1 550542 D 85963 CDS NP_223218.1 15611567 889067 551425..552108 1 NC_000921.1 similar to H. pylori 26695 gene HP0553; hypothetical protein 552108 889067 jhp0500 Helicobacter pylori J99 hypothetical protein NP_223218.1 551425 D 85963 CDS NP_223219.1 15611568 889140 552121..553086 1 NC_000921.1 similar to H. pylori 26695 gene HP0554; hypothetical protein 553086 889140 jhp0501 Helicobacter pylori J99 hypothetical protein NP_223219.1 552121 D 85963 CDS NP_223220.1 15611569 888997 553083..553904 1 NC_000921.1 similar to H. pylori 26695 gene HP0555; hypothetical protein 553904 888997 jhp0502 Helicobacter pylori J99 hypothetical protein NP_223220.1 553083 D 85963 CDS NP_223221.1 15611570 889101 complement(553975..554412) 1 NC_000921.1 similar to H. pylori 26695 gene HP0556; hypothetical protein 554412 889101 jhp0503 Helicobacter pylori J99 hypothetical protein NP_223221.1 553975 R 85963 CDS NP_223222.1 15611571 889268 complement(554894..555832) 1 NC_000921.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 555832 accA 889268 accA Helicobacter pylori J99 acetyl-CoA carboxylase carboxyltransferase subunit alpha NP_223222.1 554894 R 85963 CDS NP_223223.1 15611572 889109 complement(555854..557092) 1 NC_000921.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 557092 fabB 889109 fabB Helicobacter pylori J99 3-oxoacyl-ACP synthase NP_223223.1 555854 R 85963 CDS NP_223224.1 15611573 889121 complement(557195..557431) 1 NC_000921.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 557431 acpP 889121 acpP Helicobacter pylori J99 acyl carrier protein NP_223224.1 557195 R 85963 CDS NP_223226.1 15611575 889148 complement(557662..558405) 1 NC_000921.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 558405 fabG 889148 fabG Helicobacter pylori J99 3-ketoacyl-ACP reductase NP_223226.1 557662 R 85963 CDS NP_223227.1 15611576 889020 complement(558444..558656) 1 NC_000921.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 558656 rpsU 889020 rpsU Helicobacter pylori J99 30S ribosomal protein S21 NP_223227.1 558444 R 85963 CDS NP_223228.1 15611577 889135 complement(558757..560007) 1 NC_000921.1 similar to H. pylori 26695 gene HP0563; hypothetical protein 560007 889135 jhp0510 Helicobacter pylori J99 hypothetical protein NP_223228.1 558757 R 85963 CDS NP_223229.1 15611578 889113 560181..560426 1 NC_000921.1 similar to H. pylori 26695 gene HP0564; hypothetical protein 560426 889113 jhp0511 Helicobacter pylori J99 hypothetical protein NP_223229.1 560181 D 85963 CDS NP_223230.1 15611579 889096 complement(560450..561097) 1 NC_000921.1 similar to H. pylori 26695 gene HP0565; hypothetical protein 561097 889096 jhp0512 Helicobacter pylori J99 hypothetical protein NP_223230.1 560450 R 85963 CDS NP_223231.1 15611580 889270 complement(561210..562031) 1 NC_000921.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 562031 dapF 889270 dapF Helicobacter pylori J99 diaminopimelate epimerase NP_223231.1 561210 R 85963 CDS NP_223232.1 15611581 889128 562146..563195 1 NC_000921.1 similar to H. pylori 26695 gene HP0567; hypothetical protein 563195 889128 jhp0514 Helicobacter pylori J99 hypothetical protein NP_223232.1 562146 D 85963 CDS NP_223233.1 15611582 889070 complement(563901..564668) 1 NC_000921.1 similar to H. pylori 26695 gene HP0568; hypothetical protein 564668 889070 jhp0515 Helicobacter pylori J99 hypothetical protein NP_223233.1 563901 R 85963 CDS NP_223234.1 15611583 889111 complement(564812..565912) 1 NC_000921.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 565912 889111 jhp0516 Helicobacter pylori J99 GTP-dependent nucleic acid-binding protein EngD NP_223234.1 564812 R 85963 CDS NP_223235.1 15611584 889103 complement(565914..567404) 1 NC_000921.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 567404 pepA 889103 pepA Helicobacter pylori J99 leucyl aminopeptidase NP_223235.1 565914 R 85963 CDS NP_223236.1 15611585 889099 complement(567452..568030) 1 NC_000921.1 similar to H. pylori 26695 gene HP0571; hypothetical protein 568030 889099 jhp0518 Helicobacter pylori J99 hypothetical protein NP_223236.1 567452 R 85963 CDS NP_223237.1 15611586 889153 complement(568045..568584) 1 NC_000921.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 568584 apt 889153 apt Helicobacter pylori J99 adenine phosphoribosyltransferase NP_223237.1 568045 R 85963 CDS NP_223238.1 15611587 889115 complement(568645..568977) 1 NC_000921.1 similar to H. pylori 26695 gene HP0573; hypothetical protein 568977 889115 jhp0520 Helicobacter pylori J99 hypothetical protein NP_223238.1 568645 R 85963 CDS NP_223239.1 15611588 889110 complement(569028..569483) 1 NC_000921.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 569483 rpi 889110 rpi Helicobacter pylori J99 ribose-5-phosphate isomerase B NP_223239.1 569028 R 85963 CDS NP_223240.1 15611589 889072 complement(569502..570200) 1 NC_000921.1 similar to H. pylori 26695 gene HP0575; hypothetical protein 570200 889072 jhp0522 Helicobacter pylori J99 hypothetical protein NP_223240.1 569502 R 85963 CDS NP_223241.1 15611590 889013 complement(570209..571081) 1 NC_000921.1 similar to H. pylori 26695 gene HP0576; signal peptidase I 571081 lepB 889013 lepB Helicobacter pylori J99 signal peptidase I NP_223241.1 570209 R 85963 CDS NP_223242.1 15611591 889062 complement(571081..571953) 1 NC_000921.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 571953 folD 889062 folD Helicobacter pylori J99 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_223242.1 571081 R 85963 CDS NP_223243.1 15611592 889018 complement(572039..574075) 1 NC_000921.1 similar to H. pylori 26695 gene HP0578; hypothetical protein 574075 889018 jhp0525 Helicobacter pylori J99 hypothetical protein NP_223243.1 572039 R 85963 CDS NP_223244.1 15611593 889150 complement(574084..574635) 1 NC_000921.1 similar to H. pylori 26695 gene HP0579; hypothetical protein 574635 889150 jhp0526 Helicobacter pylori J99 hypothetical protein NP_223244.1 574084 R 85963 CDS NP_223245.1 15611594 888992 complement(574642..575760) 1 NC_000921.1 similar to H. pylori 26695 gene HP0580; hypothetical protein 575760 888992 jhp0527 Helicobacter pylori J99 hypothetical protein NP_223245.1 574642 R 85963 CDS NP_223246.1 15611595 889156 complement(575736..576755) 1 NC_000921.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 576755 pyrC_2 889156 pyrC_2 Helicobacter pylori J99 dihydroorotase NP_223246.1 575736 R 85963 CDS NP_223247.1 15611596 889147 complement(576760..577713) 1 NC_000921.1 similar to H. pylori 26695 gene HP0582; siderophore-mediated IRON transport protein 577713 tonB_1 889147 tonB_1 Helicobacter pylori J99 siderophore-mediated IRON transport protein NP_223247.1 576760 R 85963 CDS NP_223248.1 15611597 889124 complement(577697..578578) 1 NC_000921.1 similar to H. pylori 26695 gene HP0583; hypothetical protein 578578 889124 jhp0530 Helicobacter pylori J99 hypothetical protein NP_223248.1 577697 R 85963 CDS NP_223249.1 15611598 889125 complement(578575..578946) 1 NC_000921.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 578946 fliN 889125 fliN Helicobacter pylori J99 flagellar motor switch protein NP_223249.1 578575 R 85963 CDS NP_223250.1 15611599 889127 complement(579028..579672) 1 NC_000921.1 similar to H. pylori 26695 gene HP0585; endonuclease III 579672 nth 889127 nth Helicobacter pylori J99 endonuclease III NP_223250.1 579028 R 85963 CDS NP_223251.1 15611600 889134 complement(579669..579905) 1 NC_000921.1 hypothetical protein 579905 889134 jhp0533 Helicobacter pylori J99 hypothetical protein NP_223251.1 579669 R 85963 CDS NP_223252.1 15611601 889012 complement(579902..582838) 1 NC_000921.1 similar to H. pylori 26695 gene HP0586; hypothetical protein 582838 889012 jhp0534 Helicobacter pylori J99 hypothetical protein NP_223252.1 579902 R 85963 CDS NP_223253.1 15611602 888990 582756..583745 1 NC_000921.1 similar to H. pylori 26695 gene HP0587; hypothetical protein 583745 888990 jhp0535 Helicobacter pylori J99 hypothetical protein NP_223253.1 582756 D 85963 CDS NP_223254.1 15611603 889073 583930..584271 1 NC_000921.1 similar to H. pylori 26695 gene HP0588; 2-oxoglutarate-acceptor oxidoreductase subunit OorD 584271 oorD 889073 oorD Helicobacter pylori J99 2-oxoglutarate-acceptor oxidoreductase subunit OorD NP_223254.1 583930 D 85963 CDS NP_223255.1 15611604 889060 584271..585398 1 NC_000921.1 Couples the complete acetyl-CoA oxidation to aromatic ring reduction by the use of the low-potential electron shuttle ferredoxin; 2-oxoglutarate-acceptor oxidoreductase subunit OorA 585398 oorA 889060 oorA Helicobacter pylori J99 2-oxoglutarate-acceptor oxidoreductase subunit OorA NP_223255.1 584271 D 85963 CDS NP_223256.1 15611605 889085 585400..586221 1 NC_000921.1 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin; 2-oxoglutarate-acceptor oxidoreductase subunit OorB 586221 oorB 889085 oorB Helicobacter pylori J99 2-oxoglutarate-acceptor oxidoreductase subunit OorB NP_223256.1 585400 D 85963 CDS NP_223257.1 15611606 889088 586221..586775 1 NC_000921.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; 2-oxoglutarate-acceptor oxidoreductase subunit OorC 586775 oorC 889088 oorC Helicobacter pylori J99 2-oxoglutarate-acceptor oxidoreductase subunit OorC NP_223257.1 586221 D 85963 CDS NP_223258.1 15611607 889102 586889..588664 1 NC_000921.1 hypothetical protein 588664 889102 jhp0540 Helicobacter pylori J99 hypothetical protein NP_223258.1 586889 D 85963 CDS NP_223259.1 15611608 889089 588823..588987 1 NC_000921.1 similar to H. pylori 26695 gene HP0594; hypothetical protein 588987 889089 jhp0541 Helicobacter pylori J99 hypothetical protein NP_223259.1 588823 D 85963 CDS NP_223260.1 15611609 889112 588997..590469 1 NC_000921.1 similar to H. pylori 26695 gene HP0595; hypothetical protein 590469 889112 jhp0542 Helicobacter pylori J99 hypothetical protein NP_223260.1 588997 D 85963 CDS NP_223261.1 15611610 889164 590938..591516 1 NC_000921.1 Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein 591516 889164 jhp0543 Helicobacter pylori J99 tumor necrosis factor alpha-inducing protein NP_223261.1 590938 D 85963 CDS NP_223262.1 15611611 889120 complement(591519..593501) 1 NC_000921.1 similar to H. pylori 26695 gene HP0597; penicillin-binding protein 593501 889120 jhp0544 Helicobacter pylori J99 penicillin-binding protein NP_223262.1 591519 R 85963 CDS NP_223263.1 15611612 889163 complement(593501..594622) 1 NC_000921.1 similar to H. pylori 26695 gene HP0598; 8-amino-7-oxononanoate synthase 594622 bioF 889163 bioF Helicobacter pylori J99 8-amino-7-oxononanoate synthase NP_223263.1 593501 R 85963 CDS NP_223264.1 15611613 889169 complement(594645..595946) 1 NC_000921.1 similar to H. pylori 26695 gene HP0599; methyl-accepting chemotaxis protein (MCP) 595946 889169 jhp0546 Helicobacter pylori J99 methyl-accepting chemotaxis protein (MCP) NP_223264.1 594645 R 85963 CDS NP_223265.1 15611614 888995 complement(596018..597787) 1 NC_000921.1 similar to H. pylori 26695 gene HP0600; secretion/efflux ABC transporter ATP-binding protein 597787 888995 jhp0547 Helicobacter pylori J99 secretion/efflux ABC transporter ATP-binding protein NP_223265.1 596018 R 85963 CDS NP_223266.1 15611615 889160 597954..599486 1 NC_000921.1 FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A 599486 flaA 889160 flaA Helicobacter pylori J99 flagellin A NP_223266.1 597954 D 85963 CDS NP_223267.1 15611616 888986 599604..600260 1 NC_000921.1 similar to H. pylori 26695 gene HP0602; 3-methyladenine DNA glycosylase 600260 888986 jhp0549 Helicobacter pylori J99 3-methyladenine DNA glycosylase NP_223267.1 599604 D 85963 CDS NP_223268.1 15611617 889177 600257..600874 1 NC_000921.1 similar to H. pylori 26695 gene HP0603; hypothetical protein 600874 889177 jhp0550 Helicobacter pylori J99 hypothetical protein NP_223268.1 600257 D 85963 CDS NP_223269.1 15611618 889017 600943..601962 1 NC_000921.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 601962 hemE 889017 hemE Helicobacter pylori J99 uroporphyrinogen decarboxylase NP_223269.1 600943 D 85963 CDS NP_223270.1 15611619 889074 601972..603405 1 NC_000921.1 similar to H. pylori 26695 gene HP0605; hypothetical protein 603405 889074 jhp0552 Helicobacter pylori J99 hypothetical protein NP_223270.1 601972 D 85963 CDS NP_223271.1 15611620 889063 603416..604120 1 NC_000921.1 similar to H. pylori 26695 gene HP0606; efflux transporter 604120 889063 jhp0553 Helicobacter pylori J99 efflux transporter NP_223271.1 603416 D 85963 CDS NP_223272.1 15611621 889022 604133..607219 1 NC_000921.1 similar to H. pylori 26695 gene HP0607; efflux transporter 607219 889022 jhp0554 Helicobacter pylori J99 efflux transporter NP_223272.1 604133 D 85963 CDS NP_223273.1 15611622 889034 607216..607785 1 NC_000921.1 similar to H. pylori 26695 gene HP0608; hypothetical protein 607785 889034 jhp0555 Helicobacter pylori J99 hypothetical protein NP_223273.1 607216 D 85963 CDS NP_223274.1 15611623 889167 607948..617532 1 NC_000921.1 similar to H. pylori 26695 gene HP0609 and HP0610; vacuolating cytotoxin (VacA) paralog 617532 889167 jhp0556 Helicobacter pylori J99 vacuolating cytotoxin (VacA) paralog NP_223274.1 607948 D 85963 CDS NP_223275.1 15611624 889206 complement(618350..618682) 1 NC_000921.1 similar to H. pylori 26695 gene HP0614; hypothetical protein 618682 889206 jhp0557 Helicobacter pylori J99 hypothetical protein NP_223275.1 618350 R 85963 CDS NP_223276.1 15611625 889265 complement(618855..620825) 1 NC_000921.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 620825 ligA 889265 ligA Helicobacter pylori J99 NAD-dependent DNA ligase LigA NP_223276.1 618855 R 85963 CDS NP_223277.1 15611626 889264 620896..621837 1 NC_000921.1 similar to H. pylori 26695 gene HP0616; chemotaxis protein 621837 cheV_2 889264 cheV_2 Helicobacter pylori J99 chemotaxis protein NP_223277.1 620896 D 85963 CDS NP_223278.1 15611627 889250 621872..623611 1 NC_000921.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 623611 aspS 889250 aspS Helicobacter pylori J99 aspartyl-tRNA synthetase NP_223278.1 621872 D 85963 CDS NP_223279.1 15611628 889263 623623..624198 1 NC_000921.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 624198 adk 889263 adk Helicobacter pylori J99 adenylate kinase NP_223279.1 623623 D 85963 CDS NP_223280.1 15611629 889251 624223..625221 1 NC_000921.1 lipopolysaccharide biosynthesis protein 625221 889251 jhp0562 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223280.1 624223 D 85963 CDS NP_223281.1 15611630 890353 join(625240..625777,625779..626575) 1 NC_000921.1 similar to TIGR HP0619; expression of this protein is predicted to be regulated by slipped-strand repair at the (C) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; lipopolysaccharide biosynthesis protein 626575 890353 jhp0563 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223281.1 625240 D 85963 CDS NP_223282.1 15611631 890356 626631..627152 1 NC_000921.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 627152 ppa 890356 ppa Helicobacter pylori J99 inorganic pyrophosphatase NP_223282.1 626631 D 85963 CDS NP_223283.1 15611632 890351 complement(627301..629589) 1 NC_000921.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 629589 mutS 890351 mutS Helicobacter pylori J99 recombination and DNA strand exchange inhibitor protein NP_223283.1 627301 R 85963 CDS NP_223284.1 15611633 890354 complement(629550..629912) 1 NC_000921.1 similar to H. pylori 26695 gene HP0622; hypothetical protein 629912 890354 jhp0566 Helicobacter pylori J99 hypothetical protein NP_223284.1 629550 R 85963 CDS NP_223285.1 15611634 890352 complement(629912..631261) 1 NC_000921.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 631261 murC 890352 murC Helicobacter pylori J99 UDP-N-acetylmuramate--L-alanine ligase NP_223285.1 629912 R 85963 CDS NP_223286.1 15611635 890350 complement(631254..632381) 1 NC_000921.1 similar to H. pylori 26695 gene HP0624; hypothetical protein 632381 890350 jhp0568 Helicobacter pylori J99 hypothetical protein NP_223286.1 631254 R 85963 CDS NP_223287.1 15611636 890349 632534..633613 1 NC_000921.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 633613 ispG 890349 ispG Helicobacter pylori J99 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_223287.1 632534 D 85963 CDS NP_223288.1 15611637 890348 633616..634821 1 NC_000921.1 similar to H. pylori 26695 gene HP0626; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 634821 dapD 890348 dapD Helicobacter pylori J99 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase NP_223288.1 633616 D 85963 CDS NP_223289.1 15611638 890347 634833..635891 1 NC_000921.1 similar to H. pylori 26695 gene HP0627 and HP0628; hypothetical protein 635891 890347 jhp0571 Helicobacter pylori J99 hypothetical protein NP_223289.1 634833 D 85963 CDS NP_223290.1 15611639 890346 636104..638155 1 NC_000921.1 similar to H. pylori 26695 gene HP0629; hypothetical protein 638155 890346 jhp0572 Helicobacter pylori J99 hypothetical protein NP_223290.1 636104 D 85963 CDS NP_223291.1 15611640 890345 complement(638201..638785) 1 NC_000921.1 similar to H. pylori 26695 gene HP0630; hypothetical protein 638785 890345 jhp0573 Helicobacter pylori J99 hypothetical protein NP_223291.1 638201 R 85963 CDS NP_223292.1 15611641 890344 638943..640097 1 NC_000921.1 similar to H. pylori 26695 gene HP0631; hydrogenase, small subunit 640097 hyaA 890344 hyaA Helicobacter pylori J99 hydrogenase, small subunit NP_223292.1 638943 D 85963 CDS NP_223293.1 15611642 890341 640107..641843 1 NC_000921.1 similar to H. pylori 26695 gene HP0632; hydrogenase, large subunit 641843 hyaB 890341 hyaB Helicobacter pylori J99 hydrogenase, large subunit NP_223293.1 640107 D 85963 CDS NP_223294.1 15611643 890342 641856..642530 1 NC_000921.1 similar to H. pylori 26695 gene HP0633; hydrogenase, cytochrome subunit 642530 hyaC 890342 hyaC Helicobacter pylori J99 hydrogenase, cytochrome subunit NP_223294.1 641856 D 85963 CDS NP_223295.1 15611644 890343 642527..643063 1 NC_000921.1 similar to H. pylori 26695 gene HP0634; hydrogenase expression/formation protein 643063 hyaD 890343 hyaD Helicobacter pylori J99 hydrogenase expression/formation protein NP_223295.1 642527 D 85963 CDS NP_223296.1 15611645 890337 643065..644603 1 NC_000921.1 similar to H. pylori 26695 gene HP0635; hypothetical protein 644603 890337 jhp0578 Helicobacter pylori J99 hypothetical protein NP_223296.1 643065 D 85963 CDS NP_223297.1 15611646 890340 complement(644608..645021) 1 NC_000921.1 similar to H. pylori 26695 gene HP0636; hypothetical protein 645021 890340 jhp0579 Helicobacter pylori J99 hypothetical protein NP_223297.1 644608 R 85963 CDS NP_223298.1 15611647 890339 complement(645140..645592) 1 NC_000921.1 similar to H. pylori 26695 gene HP0637; hypothetical protein 645592 890339 jhp0580 Helicobacter pylori J99 hypothetical protein NP_223298.1 645140 R 85963 CDS NP_223299.1 15611648 890338 645773..646696 1 NC_000921.1 similar to H. pylori 26695 gene HP0638; hypothetical protein 646696 890338 jhp0581 Helicobacter pylori J99 hypothetical protein NP_223299.1 645773 D 85963 CDS NP_223300.1 15611649 890330 complement(646935..647612) 1 NC_000921.1 similar to H. pylori 26695 gene HP0639; hypothetical protein 647612 890330 jhp0582 Helicobacter pylori J99 hypothetical protein NP_223300.1 646935 R 85963 CDS NP_223301.1 15611650 890335 647674..648882 1 NC_000921.1 similar to H. pylori 26695 gene HP0640; polynucleotide adenylyltransferase 648882 pcnB 890335 pcnB Helicobacter pylori J99 polynucleotide adenylyltransferase NP_223301.1 647674 D 85963 CDS NP_223302.1 15611651 890333 648903..649406 1 NC_000921.1 similar to H. pylori 26695 gene HP0641; hypothetical protein 649406 890333 jhp0584 Helicobacter pylori J99 hypothetical protein NP_223302.1 648903 D 85963 CDS NP_223303.1 15611652 890332 649421..650278 1 NC_000921.1 3-hydroxyacid dehydrogenase 650278 890332 jhp0585 Helicobacter pylori J99 3-hydroxyacid dehydrogenase NP_223303.1 649421 D 85963 CDS NP_223304.1 15611653 890331 650280..650933 1 NC_000921.1 similar to H. pylori 26695 gene HP0642; NAD(P)H-flavin oxidoreductase 650933 890331 jhp0586 Helicobacter pylori J99 NAD(P)H-flavin oxidoreductase NP_223304.1 650280 D 85963 CDS NP_223305.1 15611654 890329 complement(650990..651229) 1 NC_000921.1 hypothetical protein 651229 890329 jhp0587 Helicobacter pylori J99 hypothetical protein NP_223305.1 650990 R 85963 CDS NP_223306.1 15611655 890324 651258..652577 1 NC_000921.1 charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase 652577 gltX 890324 gltX Helicobacter pylori J99 glutamylglutaminyl-tRNA synthetase NP_223306.1 651258 D 85963 CDS NP_223307.1 15611656 890327 652574..652867 1 NC_000921.1 similar to H. pylori 26695 gene HP0644; hypothetical protein 652867 890327 jhp0589 Helicobacter pylori J99 hypothetical protein NP_223307.1 652574 D 85963 CDS NP_223308.1 15611657 890325 652876..654558 1 NC_000921.1 similar to H. pylori 26695 gene HP0645; lytic murein transglycosylase 654558 890325 jhp0590 Helicobacter pylori J99 lytic murein transglycosylase NP_223308.1 652876 D 85963 CDS NP_223309.1 15611658 890326 654555..655376 1 NC_000921.1 similar to H. pylori 26695 gene HP0646; UTP-glucose-1-phosphate uridylyltransferase 655376 galU 890326 galU Helicobacter pylori J99 UTP-glucose-1-phosphate uridylyltransferase NP_223309.1 654555 D 85963 CDS NP_223310.1 15611659 890322 655388..655795 1 NC_000921.1 similar to H. pylori 26695 gene HP0647; hypothetical protein 655795 890322 jhp0592 Helicobacter pylori J99 hypothetical protein NP_223310.1 655388 D 85963 CDS NP_223311.1 15611660 890317 655798..657066 1 NC_000921.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 657066 murA 890317 murA Helicobacter pylori J99 UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_223311.1 655798 D 85963 CDS NP_223312.1 15611661 890323 657124..658530 1 NC_000921.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 658530 aspA 890323 aspA Helicobacter pylori J99 aspartate ammonia-lyase NP_223312.1 657124 D 85963 CDS NP_223313.1 15611662 890320 658536..659165 1 NC_000921.1 similar to H. pylori 26695 gene HP0650; hypothetical protein 659165 890320 jhp0595 Helicobacter pylori J99 hypothetical protein NP_223313.1 658536 D 85963 CDS NP_223314.1 15611663 890321 complement(659174..660538) 1 NC_000921.1 similar to H. pylori 26695 gene HP0651; alpha (1,3)-fucosyltransferase 660538 fucT 890321 fucT Helicobacter pylori J99 alpha (1,3)-fucosyltransferase NP_223314.1 659174 R 85963 CDS NP_223315.1 15611664 890318 complement(660576..661199) 1 NC_000921.1 similar to H. pylori 26695 gene HP0652; phosphoserine phosphatase 661199 serB 890318 serB Helicobacter pylori J99 phosphoserine phosphatase NP_223315.1 660576 R 85963 CDS NP_223316.1 15611665 890319 complement(661214..661717) 1 NC_000921.1 similar to H. pylori 26695 gene HP0653; nonheme iron-containing ferritin 661717 pfr 890319 pfr Helicobacter pylori J99 nonheme iron-containing ferritin NP_223316.1 661214 R 85963 CDS NP_223317.1 15611666 890304 662016..663098 1 NC_000921.1 similar to H. pylori 26695 gene HP0654; hypothetical protein 663098 890304 jhp0599 Helicobacter pylori J99 hypothetical protein NP_223317.1 662016 D 85963 CDS NP_223318.1 15611667 890316 663181..665901 1 NC_000921.1 similar to H. pylori 26695 gene HP0655; protective surface antigen D15 665901 890316 jhp0600 Helicobacter pylori J99 protective surface antigen D15 NP_223318.1 663181 D 85963 CDS NP_223319.1 15611668 890313 665903..666964 1 NC_000921.1 similar to H. pylori 26695 gene HP0656; hypothetical protein 666964 890313 jhp0601 Helicobacter pylori J99 hypothetical protein NP_223319.1 665903 D 85963 CDS NP_223320.1 15611669 890315 666970..668277 1 NC_000921.1 similar to H. pylori 26695 gene HP0657; processing protease 668277 890315 jhp0602 Helicobacter pylori J99 processing protease NP_223320.1 666970 D 85963 CDS NP_223321.1 15611670 890314 668277..669701 1 NC_000921.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 669701 gatB 890314 gatB Helicobacter pylori J99 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_223321.1 668277 D 85963 CDS NP_223322.1 15611671 890312 669701..670942 1 NC_000921.1 similar to H. pylori 26695 gene HP0659; hypothetical protein 670942 890312 jhp0604 Helicobacter pylori J99 hypothetical protein NP_223322.1 669701 D 85963 CDS NP_223323.1 15611672 890310 670952..671959 1 NC_000921.1 similar to H. pylori 26695 gene HP0660; hypothetical protein 671959 890310 jhp0605 Helicobacter pylori J99 hypothetical protein NP_223323.1 670952 D 85963 CDS NP_223324.1 15611673 890309 671961..672392 1 NC_000921.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 672392 rnhA 890309 rnhA Helicobacter pylori J99 ribonuclease H NP_223324.1 671961 D 85963 CDS NP_223325.1 15611674 890308 672404..673123 1 NC_000921.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 673123 rnc 890308 rnc Helicobacter pylori J99 ribonuclease III NP_223325.1 672404 D 85963 CDS NP_223326.1 15611675 890307 673120..674217 1 NC_000921.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 674217 aroC 890307 aroC Helicobacter pylori J99 chorismate synthase NP_223326.1 673120 D 85963 CDS NP_223327.1 15611676 890306 674254..674769 1 NC_000921.1 similar to H. pylori 26695 gene HP0664; hypothetical protein 674769 890306 jhp0609 Helicobacter pylori J99 hypothetical protein NP_223327.1 674254 D 85963 CDS NP_223328.1 15611677 890302 674769..676142 1 NC_000921.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 676142 hemN_1 890302 hemN_1 Helicobacter pylori J99 coproporphyrinogen III oxidase NP_223328.1 674769 D 85963 CDS NP_223329.1 15611678 890303 676139..677440 1 NC_000921.1 similar to H. pylori 26695 gene HP0666; glycerol-3-phosphate dehydrogenase 677440 glpC 890303 glpC Helicobacter pylori J99 glycerol-3-phosphate dehydrogenase NP_223329.1 676139 D 85963 CDS NP_223330.1 15611679 890301 677518..678870 1 NC_000921.1 similar to H. pylori 26695 gene HP0667 and HP0668; hypothetical protein 678870 890301 jhp0612 Helicobacter pylori J99 hypothetical protein NP_223330.1 677518 D 85963 CDS NP_223331.1 15611680 890299 678872..682375 1 NC_000921.1 similar to H. pylori 26695 gene HP0669; hypothetical protein 682375 890299 jhp0613 Helicobacter pylori J99 hypothetical protein NP_223331.1 678872 D 85963 CDS NP_223332.1 15611681 890300 682624..683436 1 NC_000921.1 similar to H. pylori 26695 gene HP0671; hypothetical protein 683436 890300 jhp0614 Helicobacter pylori J99 hypothetical protein NP_223332.1 682624 D 85963 CDS NP_223333.1 15611682 890295 683596..684768 1 NC_000921.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 684768 aspB 890295 aspB Helicobacter pylori J99 aspartate aminotransferase NP_223333.1 683596 D 85963 CDS NP_223334.1 15611683 890298 684935..685726 1 NC_000921.1 hypothetical protein 685726 890298 jhp0616 Helicobacter pylori J99 hypothetical protein NP_223334.1 684935 D 85963 CDS NP_223335.1 15611684 890296 685741..686811 1 NC_000921.1 similar to H. pylori 26695 gene HP0675; integrase-recombinase (XERCD family) 686811 890296 jhp0617 Helicobacter pylori J99 integrase-recombinase (XERCD family) NP_223335.1 685741 D 85963 CDS NP_223336.1 15611685 890297 complement(686875..687381) 1 NC_000921.1 similar to H. pylori 26695 gene HP0676; methylated-DNA--protein-cysteine methyltransferase 687381 ogt 890297 ogt Helicobacter pylori J99 methylated-DNA--protein-cysteine methyltransferase NP_223336.1 686875 R 85963 CDS NP_223337.1 15611686 890286 complement(687381..688148) 1 NC_000921.1 similar to H. pylori 26695 gene HP0677; hypothetical protein 688148 890286 jhp0619 Helicobacter pylori J99 hypothetical protein NP_223337.1 687381 R 85963 CDS NP_223338.1 15611687 890293 complement(688273..689220) 1 NC_000921.1 similar to H. pylori 26695 gene HP0679; lipopolysaccharide biosynthesis protein 689220 890293 jhp0620 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223338.1 688273 R 85963 CDS NP_223339.1 15611688 890291 complement(689282..691648) 1 NC_000921.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 691648 nrdA 890291 nrdA Helicobacter pylori J99 ribonucleotide-diphosphate reductase subunit alpha NP_223339.1 689282 R 85963 CDS NP_223340.1 15611689 890290 complement(691820..692326) 1 NC_000921.1 similar to H. pylori 26695 gene HP0681; hypothetical protein 692326 890290 jhp0622 Helicobacter pylori J99 hypothetical protein NP_223340.1 691820 R 85963 CDS NP_223341.1 15611690 890288 complement(692366..692716) 1 NC_000921.1 similar to H. pylori 26695 gene HP0682; hypothetical protein 692716 890288 jhp0623 Helicobacter pylori J99 hypothetical protein NP_223341.1 692366 R 85963 CDS NP_223342.1 15611691 890287 complement(692908..694209) 1 NC_000921.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 694209 glmU 890287 glmU Helicobacter pylori J99 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase NP_223342.1 692908 R 85963 CDS NP_223343.1 15611692 890284 694306..695052 1 NC_000921.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 695052 fliP 890284 fliP Helicobacter pylori J99 flagellar biosynthesis protein FliP NP_223343.1 694306 D 85963 CDS NP_223344.1 15611693 890282 complement(695096..697399) 1 NC_000921.1 similar to H. pylori 26695 gene HP0686; iron(III) dicitrate transport protein 697399 fecA_1 890282 fecA_1 Helicobacter pylori J99 iron(III) dicitrate transport protein NP_223344.1 695096 R 85963 CDS NP_223345.1 15611694 890280 complement(697655..699583) 1 NC_000921.1 similar to H. pylori 26695 gene HP0687; ferrous iron transport protein B 699583 feoB 890280 feoB Helicobacter pylori J99 ferrous iron transport protein B NP_223345.1 697655 R 85963 CDS NP_223346.1 15611695 890277 699704..700534 1 NC_000921.1 similar to H. pylori 26695 gene HP0688 and HP0689; hypothetical protein 700534 890277 jhp0628 Helicobacter pylori J99 hypothetical protein NP_223346.1 699704 D 85963 CDS NP_223347.1 15611696 890281 700587..701801 1 NC_000921.1 type II DNA modification enzyme 701801 890281 jhp0629 Helicobacter pylori J99 type II DNA modification enzyme NP_223347.1 700587 D 85963 CDS NP_223348.1 15611697 890279 701804..702676 1 NC_000921.1 type II restriction enzyme 702676 890279 jhp0630 Helicobacter pylori J99 type II restriction enzyme NP_223348.1 701804 D 85963 CDS NP_223349.1 15611698 890278 complement(702854..703354) 1 NC_000921.1 similar to H. pylori 26695 gene HP0697; hypothetical protein 703354 890278 jhp0631 Helicobacter pylori J99 hypothetical protein NP_223349.1 702854 R 85963 CDS NP_223350.1 15611699 890267 complement(703378..705675) 1 NC_000921.1 similar to H. pylori 26695 gene HP0696; N-methylhydantoinase 705675 890267 jhp0632 Helicobacter pylori J99 N-methylhydantoinase NP_223350.1 703378 R 85963 CDS NP_223351.1 15611700 890276 complement(705687..707825) 1 NC_000921.1 similar to H. pylori 26695 gene HP0695; hydantoin utilization 707825 890276 jhp0633 Helicobacter pylori J99 hydantoin utilization NP_223351.1 705687 R 85963 CDS NP_223352.1 15611701 890275 complement(708056..709066) 1 NC_000921.1 similar to H. pylori 26695 gene HP0694; hypothetical protein 709066 890275 jhp0634 Helicobacter pylori J99 hypothetical protein NP_223352.1 708056 R 85963 CDS NP_223353.1 15611702 890273 complement(709195..710559) 1 NC_000921.1 similar to H. pylori 26695 gene HP0693; short-chain fatty acids transporter 710559 atoE 890273 atoE Helicobacter pylori J99 short-chain fatty acids transporter NP_223353.1 709195 R 85963 CDS NP_223354.1 15611703 890274 complement(710579..711202) 1 NC_000921.1 similar to H. pylori 26695 gene HP0692; 3-oxoacid CoA-transferase subunit B 711202 scoB 890274 scoB Helicobacter pylori J99 3-oxoacid CoA-transferase subunit B NP_223354.1 710579 R 85963 CDS NP_223355.1 15611704 890270 complement(711199..711897) 1 NC_000921.1 similar to H. pylori 26695 gene HP0691; 3-oxoacid CoA-transferase subunit A 711897 scoA 890270 scoA Helicobacter pylori J99 3-oxoacid CoA-transferase subunit A NP_223355.1 711199 R 85963 CDS NP_223356.1 15611705 890271 complement(711908..713083) 1 NC_000921.1 similar to H. pylori 26695 gene HP0690; acetyl-COA acetyltransferase 713083 thl 890271 thl Helicobacter pylori J99 acetyl-COA acetyltransferase NP_223356.1 711908 R 85963 CDS NP_223357.1 15611706 890269 713348..714376 1 NC_000921.1 similar to H. pylori 26695 gene HP0699; hypothetical protein 714376 890269 jhp0639 Helicobacter pylori J99 hypothetical protein NP_223357.1 713348 D 85963 CDS NP_223358.1 15611707 890264 714369..714755 1 NC_000921.1 similar to H. pylori 26695 gene HP0700; diacylglycerol kinase 714755 dgkA 890264 dgkA Helicobacter pylori J99 diacylglycerol kinase NP_223358.1 714369 D 85963 CDS NP_223359.1 15611708 890268 714771..717257 1 NC_000921.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 717257 gyrA 890268 gyrA Helicobacter pylori J99 DNA gyrase subunit A NP_223359.1 714771 D 85963 CDS NP_223360.1 15611709 890266 717257..717730 1 NC_000921.1 similar to H. pylori 26695 gene HP0702; hypothetical protein 717730 890266 jhp0642 Helicobacter pylori J99 hypothetical protein NP_223360.1 717257 D 85963 CDS NP_223361.1 15611710 890265 717727..718872 1 NC_000921.1 similar to H. pylori 26695 gene HP0703; transcriptional regulator 718872 890265 jhp0643 Helicobacter pylori J99 transcriptional regulator NP_223361.1 717727 D 85963 CDS NP_223362.1 15611711 890262 complement(719545..722370) 1 NC_000921.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 722370 uvrA 890262 uvrA Helicobacter pylori J99 excinuclease ABC subunit A NP_223362.1 719545 R 85963 CDS NP_223363.1 15611712 890263 722544..723356 1 NC_000921.1 similar to H. pylori 26695 gene HP0706; Outer membrane protein/porin 723356 hopE 890263 hopE Helicobacter pylori J99 Outer membrane protein/porin NP_223363.1 722544 D 85963 CDS NP_223364.1 15611713 890261 723528..724454 1 NC_000921.1 similar to H. pylori 26695 gene HP0707; S-adenosyl-methyltransferase MraW 724454 mraW 890261 mraW Helicobacter pylori J99 S-adenosyl-methyltransferase MraW NP_223364.1 723528 D 85963 CDS NP_223365.1 15611714 890260 724475..724819 1 NC_000921.1 similar to H. pylori 26695 gene HP0708; hypothetical protein 724819 890260 jhp0647 Helicobacter pylori J99 hypothetical protein NP_223365.1 724475 D 85963 CDS NP_223366.1 15611715 890256 725292..726194 1 NC_000921.1 similar to H. pylori 26695 gene HP0709; hypothetical protein 726194 890256 jhp0648 Helicobacter pylori J99 hypothetical protein NP_223366.1 725292 D 85963 CDS NP_223367.1 15611716 890259 726428..728401 1 NC_000921.1 similar to H. pylori 26695 gene HP0710; hypothetical protein 728401 890259 jhp0649 Helicobacter pylori J99 hypothetical protein NP_223367.1 726428 D 85963 CDS NP_223368.1 15611717 890257 728591..729811 1 NC_000921.1 similar to H. pylori 26695 gene HP0711; hypothetical protein 729811 890257 jhp0650 Helicobacter pylori J99 hypothetical protein NP_223368.1 728591 D 85963 CDS NP_223369.1 15611718 890255 729811..730515 1 NC_000921.1 similar to H. pylori 26695 gene HP0712 and HP0713; hypothetical protein 730515 890255 jhp0651 Helicobacter pylori J99 hypothetical protein NP_223369.1 729811 D 85963 CDS NP_223370.1 15611719 890249 complement(730527..731771) 1 NC_000921.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 731771 rpoN 890249 rpoN Helicobacter pylori J99 RNA polymerase factor sigma-54 NP_223370.1 730527 R 85963 CDS NP_223371.1 15611720 890253 complement(731774..732496) 1 NC_000921.1 similar to H. pylori 26695 gene HP0715; ABC transporter ATP-binding protein 732496 890253 jhp0653 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_223371.1 731774 R 85963 CDS NP_223372.1 15611721 890252 complement(732509..732910) 1 NC_000921.1 similar to H. pylori 26695 gene HP0716; hypothetical protein 732910 890252 jhp0654 Helicobacter pylori J99 hypothetical protein NP_223372.1 732509 R 85963 CDS NP_223373.1 15611722 890248 complement(732907..734655) 1 NC_000921.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau 734655 dnaX 890248 dnaX Helicobacter pylori J99 DNA polymerase III subunits gamma/tau NP_223373.1 732907 R 85963 CDS NP_223374.1 15611723 890247 complement(734722..735354) 1 NC_000921.1 similar to H. pylori 26695 gene HP0718; hypothetical protein 735354 890247 jhp0656 Helicobacter pylori J99 hypothetical protein NP_223374.1 734722 R 85963 CDS NP_223375.1 15611724 890246 735622..736044 1 NC_000921.1 similar to H. pylori 26695 gene HP0719 and HP0720; hypothetical protein 736044 890246 jhp0657 Helicobacter pylori J99 hypothetical protein NP_223375.1 735622 D 85963 CDS NP_223376.1 15611725 890245 736072..736530 1 NC_000921.1 similar to H. pylori 26695 gene HP0721; hypothetical protein 736530 890245 jhp0658 Helicobacter pylori J99 hypothetical protein NP_223376.1 736072 D 85963 CDS NP_223377.1 15611726 890244 join(736846..736882,736881..738760) 1 NC_000921.1 similar to TIGR HP0722; expression of this protein is predicted to be regulated by slipped-strand repair at the (CT) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein 738760 890244 jhp0659 Helicobacter pylori J99 hypothetical protein NP_223377.1 736846 D 85963 CDS NP_223378.1 15611727 890241 complement(738830..740161) 1 NC_000921.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 740161 dcuA 890241 dcuA Helicobacter pylori J99 anaerobic C4-dicarboxylate transporter NP_223378.1 738830 R 85963 CDS NP_223379.1 15611728 890242 740291..741289 1 NC_000921.1 similar to H. pylori 26695 gene HP0723; L-asparaginase II 741289 ansB 890242 ansB Helicobacter pylori J99 L-asparaginase II NP_223379.1 740291 D 85963 CDS NP_223380.1 15611729 890243 complement(join(741428..743346,743345..743381)) 1 NC_000921.1 similar to TIGR HP0725; expression of this protein is predicted to be regulated by slipped-strand repair at the (CT) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein 743381 890243 jhp0662 Helicobacter pylori J99 hypothetical protein NP_223380.1 741428 R 85963 CDS NP_223381.1 15611730 890240 complement(743602..744519) 1 NC_000921.1 similar to H. pylori 26695 gene HP0726; hypothetical protein 744519 890240 jhp0663 Helicobacter pylori J99 hypothetical protein NP_223381.1 743602 R 85963 CDS NP_223382.1 15611731 890235 complement(744489..745475) 1 NC_000921.1 similar to H. pylori 26695 gene HP0727; transcriptional regulator 745475 890235 jhp0664 Helicobacter pylori J99 transcriptional regulator NP_223382.1 744489 R 85963 CDS NP_223383.1 15611732 890236 complement(745569..746585) 1 NC_000921.1 similar to H. pylori 26695 gene HP0728; hypothetical protein 746585 890236 jhp0665 Helicobacter pylori J99 hypothetical protein NP_223383.1 745569 R 85963 CDS NP_223384.1 15611733 890239 complement(746621..747688) 1 NC_000921.1 similar to H. pylori 26695 gene HP0729; hypothetical protein 747688 890239 jhp0666 Helicobacter pylori J99 hypothetical protein NP_223384.1 746621 R 85963 CDS NP_223385.1 15611734 890237 complement(747697..748002) 1 NC_000921.1 similar to H. pylori 26695 gene HP0730; hypothetical protein 748002 890237 jhp0667 Helicobacter pylori J99 hypothetical protein NP_223385.1 747697 R 85963 CDS NP_223386.1 15611735 890232 complement(748118..749827) 1 NC_000921.1 similar to H. pylori 26695 gene HP0731; hypothetical protein 749827 890232 jhp0668 Helicobacter pylori J99 hypothetical protein NP_223386.1 748118 R 85963 CDS NP_223387.1 15611736 890233 complement(749817..750932) 1 NC_000921.1 similar to H. pylori 26695 gene HP0732; hypothetical protein 750932 890233 jhp0669 Helicobacter pylori J99 hypothetical protein NP_223387.1 749817 R 85963 CDS NP_223388.1 15611737 890228 complement(750989..751567) 1 NC_000921.1 similar to H. pylori 26695 gene HP0733; hypothetical protein 751567 890228 jhp0670 Helicobacter pylori J99 hypothetical protein NP_223388.1 750989 R 85963 CDS NP_223389.1 15611738 890222 complement(751670..752989) 1 NC_000921.1 similar to H. pylori 26695 gene HP0734; hypothetical protein 752989 890222 jhp0671 Helicobacter pylori J99 hypothetical protein NP_223389.1 751670 R 85963 CDS NP_223390.1 15611739 890227 complement(752991..753452) 1 NC_000921.1 similar to H. pylori 26695 gene HP0735; xanthine-guanine phosphoribosyltransferase 753452 gpt 890227 gpt Helicobacter pylori J99 xanthine-guanine phosphoribosyltransferase NP_223390.1 752991 R 85963 CDS NP_223391.1 15611740 890226 complement(753461..754570) 1 NC_000921.1 similar to H. pylori 26695 gene HP0736; aminotransferase 754570 890226 jhp0673 Helicobacter pylori J99 aminotransferase NP_223391.1 753461 R 85963 CDS NP_223392.1 15611741 890225 754717..755193 1 NC_000921.1 similar to H. pylori 26695 gene HP0737; phosphatidylglycerophosphatase A 755193 pgpA 890225 pgpA Helicobacter pylori J99 phosphatidylglycerophosphatase A NP_223392.1 754717 D 85963 CDS NP_223393.1 15611742 890224 755270..756313 1 NC_000921.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 756313 ddl 890224 ddl Helicobacter pylori J99 D-alanyl-alanine synthetase A NP_223393.1 755270 D 85963 CDS NP_223394.1 15611743 890223 756314..757039 1 NC_000921.1 similar to H. pylori 26695 gene HP0739; 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase 757039 890223 jhp0676 Helicobacter pylori J99 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase NP_223394.1 756314 D 85963 CDS NP_223395.1 15611744 890221 757026..758507 1 NC_000921.1 similar to H. pylori 26695 gene HP0740; D-alanyl-D-alanine-adding enzyme 758507 murF 890221 murF Helicobacter pylori J99 D-alanyl-D-alanine-adding enzyme NP_223395.1 757026 D 85963 CDS NP_223396.1 15611745 890220 758517..759002 1 NC_000921.1 similar to H. pylori 26695 gene HP0741; HIT family protein 759002 890220 jhp0678 Helicobacter pylori J99 HIT family protein NP_223396.1 758517 D 85963 CDS NP_223397.1 15611746 890219 759067..760023 1 NC_000921.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 760023 prsA 890219 prsA Helicobacter pylori J99 ribose-phosphate pyrophosphokinase NP_223397.1 759067 D 85963 CDS NP_223398.1 15611747 890218 complement(760074..761219) 1 NC_000921.1 similar to H. pylori 26695 gene HP0743; rod shape-determining protein 761219 rodA_1 890218 rodA_1 Helicobacter pylori J99 rod shape-determining protein NP_223398.1 760074 R 85963 CDS NP_223399.1 15611748 890217 complement(join(761242..762008,762007..762454)) 1 NC_000921.1 similar to TIGR HP0744; expression of this protein is predicted to be regulated by slipped-strand repair at the (AG) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein 762454 890217 jhp0681 Helicobacter pylori J99 hypothetical protein NP_223399.1 761242 R 85963 CDS NP_223400.1 15611749 890213 762588..763571 1 NC_000921.1 similar to H. pylori 26695 gene HP0745; hypothetical protein 763571 890213 jhp0682 Helicobacter pylori J99 hypothetical protein NP_223400.1 762588 D 85963 CDS NP_223401.1 15611750 890216 763522..764781 1 NC_000921.1 similar to H. pylori 26695 gene HP0746; hypothetical protein 764781 890216 jhp0683 Helicobacter pylori J99 hypothetical protein NP_223401.1 763522 D 85963 CDS NP_223402.1 15611751 890215 764792..765994 1 NC_000921.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 765994 trmB 890215 trmB Helicobacter pylori J99 tRNA (guanine-N(7)-)-methyltransferase NP_223402.1 764792 D 85963 CDS NP_223403.1 15611752 890214 765969..766640 1 NC_000921.1 similar to H. pylori 26695 gene HP0748; ABC transporter ATP-binding protein 766640 890214 jhp0685 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_223403.1 765969 D 85963 CDS NP_223404.1 15611753 890211 766627..767433 1 NC_000921.1 similar to H. pylori 26695 gene HP0749; hypothetical protein 767433 890211 jhp0686 Helicobacter pylori J99 hypothetical protein NP_223404.1 766627 D 85963 CDS NP_223405.1 15611754 890204 767426..768628 1 NC_000921.1 similar to H. pylori 26695 gene HP0750; hypothetical protein 768628 890204 jhp0687 Helicobacter pylori J99 hypothetical protein NP_223405.1 767426 D 85963 CDS NP_223406.1 15611755 890212 768725..769084 1 NC_000921.1 possibly involved in flagella export; flagellar protein FlaG 769084 890212 jhp0688 Helicobacter pylori J99 flagellar protein FlaG NP_223406.1 768725 D 85963 CDS NP_223407.1 15611756 890207 769101..771158 1 NC_000921.1 involved in flagellin assembly; flagellar capping protein 771158 fliD 890207 fliD Helicobacter pylori J99 flagellar capping protein NP_223407.1 769101 D 85963 CDS NP_223408.1 15611757 890210 771200..771580 1 NC_000921.1 flagellin specific chaperone; flagellar protein FliS 771580 fliS 890210 fliS Helicobacter pylori J99 flagellar protein FliS NP_223408.1 771200 D 85963 CDS NP_223409.1 15611758 890209 771567..771806 1 NC_000921.1 similar to H. pylori 26695 gene HP0754; hypothetical protein 771806 890209 jhp0691 Helicobacter pylori J99 hypothetical protein NP_223409.1 771567 D 85963 CDS NP_223410.1 15611759 890205 771859..772566 1 NC_000921.1 similar to H. pylori 26695 gene HP0755; hypothetical protein 772566 890205 jhp0692 Helicobacter pylori J99 hypothetical protein NP_223410.1 771859 D 85963 CDS NP_223411.1 15611760 890197 772532..772678 1 NC_000921.1 similar to H. pylori 26695 gene HP0756; hypothetical protein 772678 890197 jhp0693 Helicobacter pylori J99 hypothetical protein NP_223411.1 772532 D 85963 CDS NP_223412.1 15611761 890208 772682..773560 1 NC_000921.1 similar to H. pylori 26695 gene HP0757; hypothetical protein 773560 890208 jhp0694 Helicobacter pylori J99 hypothetical protein NP_223412.1 772682 D 85963 CDS NP_223413.1 15611762 890206 773687..775000 1 NC_000921.1 similar to H. pylori 26695 gene HP0758; hypothetical protein 775000 890206 jhp0695 Helicobacter pylori J99 hypothetical protein NP_223413.1 773687 D 85963 CDS NP_223414.1 15611763 890196 775063..776316 1 NC_000921.1 similar to H. pylori 26695 gene HP0759; hypothetical protein 776316 890196 jhp0696 Helicobacter pylori J99 hypothetical protein NP_223414.1 775063 D 85963 CDS NP_223415.1 15611764 890203 complement(776317..777906) 1 NC_000921.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 777906 890203 jhp0697 Helicobacter pylori J99 phosphodiesterase NP_223415.1 776317 R 85963 CDS NP_223416.1 15611765 890202 complement(777806..778408) 1 NC_000921.1 similar to H. pylori 26695 gene HP0761; hypothetical protein 778408 890202 jhp0698 Helicobacter pylori J99 hypothetical protein NP_223416.1 777806 R 85963 CDS NP_223417.1 15611766 890200 778572..779129 1 NC_000921.1 similar to H. pylori 26695 gene HP0762; hypothetical protein 779129 890200 jhp0699 Helicobacter pylori J99 hypothetical protein NP_223417.1 778572 D 85963 CDS NP_223418.1 15611767 890201 779135..780016 1 NC_000921.1 similar to H. pylori 26695 gene HP0763; hypothetical protein 780016 ftsY 890201 ftsY Helicobacter pylori J99 hypothetical protein NP_223418.1 779135 D 85963 CDS NP_223419.1 15611768 890199 complement(780303..780656) 1 NC_000921.1 similar to H. pylori 26695 gene HP0764; hypothetical protein 780656 890199 jhp0701 Helicobacter pylori J99 hypothetical protein NP_223419.1 780303 R 85963 CDS NP_223420.1 15611769 890198 complement(780684..781190) 1 NC_000921.1 similar to H. pylori 26695 gene HP0764; hypothetical protein 781190 890198 jhp0702 Helicobacter pylori J99 hypothetical protein NP_223420.1 780684 R 85963 CDS NP_223421.1 15611770 890194 complement(781141..782001) 1 NC_000921.1 similar to H. pylori 26695 gene HP0765; hypothetical protein 782001 890194 jhp0703 Helicobacter pylori J99 hypothetical protein NP_223421.1 781141 R 85963 CDS NP_223422.1 15611771 890195 complement(782013..782561) 1 NC_000921.1 similar to H. pylori 26695 gene HP0766; hypothetical protein 782561 890195 jhp0704 Helicobacter pylori J99 hypothetical protein NP_223422.1 782013 R 85963 CDS NP_223423.1 15611772 890191 complement(782926..783891) 1 NC_000921.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 783891 moaA 890191 moaA Helicobacter pylori J99 molybdenum cofactor biosynthesis protein A NP_223423.1 782926 R 85963 CDS NP_223424.1 15611773 890193 783977..784606 1 NC_000921.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 784606 mobA 890193 mobA Helicobacter pylori J99 molybdopterin-guanine dinucleotide biosynthesis protein A NP_223424.1 783977 D 85963 CDS NP_223425.1 15611774 890192 784575..785651 1 NC_000921.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 785651 flhB 890192 flhB Helicobacter pylori J99 flagellar biosynthesis protein FlhB NP_223425.1 784575 D 85963 CDS NP_223426.1 15611775 890186 complement(785746..786483) 1 NC_000921.1 similar to H. pylori 26695 gene HP0771; hypothetical protein 786483 890186 jhp0708 Helicobacter pylori J99 hypothetical protein NP_223426.1 785746 R 85963 CDS NP_223427.1 15611776 890188 complement(786502..787911) 1 NC_000921.1 similar to H. pylori 26695 gene HP0772; N-acetylmuramoyl-L-alanine amidase 787911 amiA 890188 amiA Helicobacter pylori J99 N-acetylmuramoyl-L-alanine amidase NP_223427.1 786502 R 85963 CDS NP_223428.1 15611777 890189 complement(787918..789009) 1 NC_000921.1 similar to H. pylori 26695 gene HP0773; hypothetical protein 789009 890189 jhp0710 Helicobacter pylori J99 hypothetical protein NP_223428.1 787918 R 85963 CDS NP_223429.1 15611778 890190 complement(789026..790234) 1 NC_000921.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 790234 tyrS 890190 tyrS Helicobacter pylori J99 tyrosyl-tRNA synthetase NP_223429.1 789026 R 85963 CDS NP_223430.1 15611779 890187 complement(790254..792584) 1 NC_000921.1 similar to H. pylori 26695 gene HP0775; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 792584 spoT 890187 spoT Helicobacter pylori J99 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase NP_223430.1 790254 R 85963 CDS NP_223431.1 15611780 890185 complement(792571..792795) 1 NC_000921.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 792795 890185 jhp0713 Helicobacter pylori J99 DNA-directed RNA polymerase subunit omega NP_223431.1 792571 R 85963 CDS NP_223432.1 15611781 890181 complement(792837..793559) 1 NC_000921.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 793559 pyrH 890181 pyrH Helicobacter pylori J99 uridylate kinase NP_223432.1 792837 R 85963 CDS NP_223433.1 15611782 890184 complement(793650..794333) 1 NC_000921.1 similar to H. pylori 26695 gene HP0778; hypothetical protein 794333 890184 jhp0715 Helicobacter pylori J99 hypothetical protein NP_223433.1 793650 R 85963 CDS NP_223434.1 15611783 890183 794464..797022 1 NC_000921.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 797022 acnB 890183 acnB Helicobacter pylori J99 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase NP_223434.1 794464 D 85963 CDS NP_223435.1 15611784 890182 797103..797369 1 NC_000921.1 similar to H. pylori 26695 gene HP0780; hypothetical protein 797369 890182 jhp0717 Helicobacter pylori J99 hypothetical protein NP_223435.1 797103 D 85963 CDS NP_223436.1 15611785 890180 797664..798953 1 NC_000921.1 similar to H. pylori 26695 gene HP0781; hypothetical protein 798953 890180 jhp0718 Helicobacter pylori J99 hypothetical protein NP_223436.1 797664 D 85963 CDS NP_223437.1 15611786 890177 799047..800414 1 NC_000921.1 similar to H. pylori 26695 gene HP0782; hypothetical protein 800414 890177 jhp0719 Helicobacter pylori J99 hypothetical protein NP_223437.1 799047 D 85963 CDS NP_223438.1 15611787 890178 complement(800421..800948) 1 NC_000921.1 similar to H. pylori 26695 gene HP0783; hypothetical protein 800948 890178 jhp0720 Helicobacter pylori J99 hypothetical protein NP_223438.1 800421 R 85963 CDS NP_223439.1 15611788 890179 801287..801418 1 NC_000921.1 similar to H. pylori 26695 gene HP0784; hypothetical protein 801418 890179 jhp0721 Helicobacter pylori J99 hypothetical protein NP_223439.1 801287 D 85963 CDS NP_223440.1 15611789 890175 complement(801433..801987) 1 NC_000921.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 801987 lolA 890175 lolA Helicobacter pylori J99 outer-membrane lipoprotein carrier protein NP_223440.1 801433 R 85963 CDS NP_223441.1 15611790 890173 802134..804731 1 NC_000921.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 804731 secA 890173 secA Helicobacter pylori J99 preprotein translocase subunit SecA NP_223441.1 802134 D 85963 CDS NP_223442.1 15611791 890176 804721..805953 1 NC_000921.1 similar to H. pylori 26695 gene HP0787; hypothetical protein 805953 890176 jhp0724 Helicobacter pylori J99 hypothetical protein NP_223442.1 804721 D 85963 CDS NP_223443.1 15611792 890171 806232..807731 1 NC_000921.1 similar to H. pylori 26695 gene HP0788; hypothetical protein 807731 890171 jhp0725 Helicobacter pylori J99 hypothetical protein NP_223443.1 806232 D 85963 CDS NP_223444.1 15611793 890160 complement(807943..809307) 1 NC_000921.1 type I restriction enzyme (specificity subunit) 809307 hsdS_4 890160 hsdS_4 Helicobacter pylori J99 type I restriction enzyme (specificity subunit) NP_223444.1 807943 R 85963 CDS NP_223445.1 15611794 890170 complement(809351..811411) 1 NC_000921.1 similar to H. pylori 26695 gene HP0791; heavy-metal cation-transporting P-type ATPase 811411 hmcT 890170 hmcT Helicobacter pylori J99 heavy-metal cation-transporting P-type ATPase NP_223445.1 809351 R 85963 CDS NP_223446.1 15611795 890172 complement(811436..812956) 1 NC_000921.1 similar to H. pylori 26695 gene HP0792; hypothetical protein 812956 890172 jhp0728 Helicobacter pylori J99 hypothetical protein NP_223446.1 811436 R 85963 CDS NP_223447.1 15611796 890168 complement(812962..813486) 1 NC_000921.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 813486 def 890168 def Helicobacter pylori J99 peptide deformylase NP_223447.1 812962 R 85963 CDS NP_223448.1 15611797 890167 complement(813491..814078) 1 NC_000921.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 814078 clpP 890167 clpP Helicobacter pylori J99 ATP-dependent Clp protease proteolytic subunit NP_223448.1 813491 R 85963 CDS NP_223449.1 15611798 890166 complement(814099..815454) 1 NC_000921.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 815454 tig 890166 tig Helicobacter pylori J99 trigger factor NP_223449.1 814099 R 85963 CDS NP_223450.1 15611799 890165 complement(815567..816403) 1 NC_000921.1 similar to H. pylori 26695 gene HP0796; hypothetical protein 816403 890165 jhp0732 Helicobacter pylori J99 hypothetical protein NP_223450.1 815567 R 85963 CDS NP_223451.1 15611800 890164 complement(816425..817207) 1 NC_000921.1 similar to H. pylori 26695 gene HP0797; neuraminyllactose-binding hemagglutinin precursor 817207 hpaA 890164 hpaA Helicobacter pylori J99 neuraminyllactose-binding hemagglutinin precursor NP_223451.1 816425 R 85963 CDS NP_223452.1 15611801 890163 complement(817326..817802) 1 NC_000921.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 817802 moaC 890163 moaC Helicobacter pylori J99 molybdenum cofactor biosynthesis protein MoaC NP_223452.1 817326 R 85963 CDS NP_223453.1 15611802 890162 complement(817811..818341) 1 NC_000921.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 818341 mogA 890162 mogA Helicobacter pylori J99 molybdenum cofactor biosynthesis protein MogA NP_223453.1 817811 R 85963 CDS NP_223454.1 15611803 890161 complement(818354..818791) 1 NC_000921.1 similar to H. pylori 26695 gene HP0800; molybdopterin converting factor, subunit 2 818791 moaE 890161 moaE Helicobacter pylori J99 molybdopterin converting factor, subunit 2 NP_223454.1 818354 R 85963 CDS NP_223455.1 15611804 890157 complement(818792..819013) 1 NC_000921.1 similar to H. pylori 26695 gene HP0801; molybdopterin converting factor, subunit 1 819013 moaD 890157 moaD Helicobacter pylori J99 molybdopterin converting factor, subunit 1 NP_223455.1 818792 R 85963 CDS NP_223456.1 15611805 890159 complement(819062..819640) 1 NC_000921.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 819640 ribA 890159 ribA Helicobacter pylori J99 GTP cyclohydrolase II NP_223456.1 819062 R 85963 CDS NP_223457.1 15611806 890158 complement(819730..820569) 1 NC_000921.1 similar to H. pylori 26695 gene HP0803; hypothetical protein 820569 890158 jhp0739 Helicobacter pylori J99 hypothetical protein NP_223457.1 819730 R 85963 CDS NP_223458.1 15611807 890155 complement(820656..821690) 1 NC_000921.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 821690 ribBA 890155 ribBA Helicobacter pylori J99 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein NP_223458.1 820656 R 85963 CDS NP_223459.1 15611808 890156 complement(821788..822666) 1 NC_000921.1 similar to H. pylori 26695 gene HP0805; lipopolysaccharide biosynthesis protein 822666 890156 jhp0741 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223459.1 821788 R 85963 CDS NP_223460.1 15611809 890152 822715..823335 1 NC_000921.1 similar to H. pylori 26695 gene HP0806; hypothetical protein 823335 890152 jhp0742 Helicobacter pylori J99 hypothetical protein NP_223460.1 822715 D 85963 CDS NP_223461.1 15611810 890153 complement(823346..825724) 1 NC_000921.1 similar to H. pylori 26695 gene HP0807; iron(III) dicitrate transport protein 825724 fecA_2 890153 fecA_2 Helicobacter pylori J99 iron(III) dicitrate transport protein NP_223461.1 823346 R 85963 CDS NP_223462.1 15611811 890149 complement(825922..826281) 1 NC_000921.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 826281 acpS 890149 acpS Helicobacter pylori J99 4'-phosphopantetheinyl transferase NP_223462.1 825922 R 85963 CDS NP_223463.1 15611812 890151 complement(826288..826839) 1 NC_000921.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 826839 fliL 890151 fliL Helicobacter pylori J99 flagellar basal body protein FliL NP_223463.1 826288 R 85963 CDS NP_223464.1 15611813 890150 complement(826848..827450) 1 NC_000921.1 similar to H. pylori 26695 gene HP0810; hypothetical protein 827450 890150 jhp0746 Helicobacter pylori J99 hypothetical protein NP_223464.1 826848 R 85963 CDS NP_223465.1 15611814 890145 complement(827429..827755) 1 NC_000921.1 similar to H. pylori 26695 gene HP0811; hypothetical protein 827755 890145 jhp0747 Helicobacter pylori J99 hypothetical protein NP_223465.1 827429 R 85963 CDS NP_223466.1 15611815 890147 complement(828209..829219) 1 NC_000921.1 similar to H. pylori 26695 gene HP0812; hypothetical protein 829219 890147 jhp0748 Helicobacter pylori J99 hypothetical protein NP_223466.1 828209 R 85963 CDS NP_223467.1 15611816 890148 829352..829969 1 NC_000921.1 similar to H. pylori 26695 gene HP0813; hypothetical protein 829969 890148 jhp0749 Helicobacter pylori J99 hypothetical protein NP_223467.1 829352 D 85963 CDS NP_223468.1 15611817 890146 829970..830737 1 NC_000921.1 similar to H. pylori 26695 gene HP0814; molybdopterin-synthase sulfurylase 830737 moeB 890146 moeB Helicobacter pylori J99 molybdopterin-synthase sulfurylase NP_223468.1 829970 D 85963 CDS NP_223469.1 15611818 890144 830753..831526 1 NC_000921.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 831526 motA 890144 motA Helicobacter pylori J99 flagellar motor protein MotA NP_223469.1 830753 D 85963 CDS NP_223470.1 15611819 890143 831529..832302 1 NC_000921.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 832302 motB 890143 motB Helicobacter pylori J99 flagellar motor protein MotB NP_223470.1 831529 D 85963 CDS NP_223471.1 15611820 890141 832299..832745 1 NC_000921.1 similar to H. pylori 26695 gene HP0817; hypothetical protein 832745 890141 jhp0753 Helicobacter pylori J99 hypothetical protein NP_223471.1 832299 D 85963 CDS NP_223472.1 15611821 890142 832859..833344 1 NC_000921.1 similar to H. pylori 26695 gene HP0818; osmoprotection binding protein 833344 890142 jhp0754 Helicobacter pylori J99 osmoprotection binding protein NP_223472.1 832859 D 85963 CDS NP_223473.1 15611822 890139 complement(833221..833793) 1 NC_000921.1 hypothetical protein 833793 890139 jhp0755 Helicobacter pylori J99 hypothetical protein NP_223473.1 833221 R 85963 CDS NP_223474.1 15611823 890137 complement(833787..834605) 1 NC_000921.1 type II DNA modification enzyme 834605 890137 jhp0756 Helicobacter pylori J99 type II DNA modification enzyme NP_223474.1 833787 R 85963 CDS NP_223475.1 15611824 890138 834901..836562 1 NC_000921.1 similar to H. pylori 26695 gene HP0818; osmoprotection binding protein 836562 890138 jhp0757 Helicobacter pylori J99 osmoprotection binding protein NP_223475.1 834901 D 85963 CDS NP_223476.1 15611825 890130 836565..837215 1 NC_000921.1 similar to H. pylori 26695 gene HP0819; osmoprotection ATP-binding protein 837215 890130 jhp0758 Helicobacter pylori J99 osmoprotection ATP-binding protein NP_223476.1 836565 D 85963 CDS NP_223477.1 15611826 890136 837390..837851 1 NC_000921.1 similar to H. pylori 26695 gene HP0820; hypothetical protein 837851 890136 jhp0759 Helicobacter pylori J99 hypothetical protein NP_223477.1 837390 D 85963 CDS NP_223478.1 15611827 890135 837852..839636 1 NC_000921.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 839636 uvrC 890135 uvrC Helicobacter pylori J99 excinuclease ABC subunit C NP_223478.1 837852 D 85963 CDS NP_223479.1 15611828 890134 839646..840911 1 NC_000921.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 840911 hom 890134 hom Helicobacter pylori J99 homoserine dehydrogenase NP_223479.1 839646 D 85963 CDS NP_223480.1 15611829 890133 840912..841256 1 NC_000921.1 similar to H. pylori 26695 gene HP0823; hypothetical protein 841256 890133 jhp0762 Helicobacter pylori J99 hypothetical protein NP_223480.1 840912 D 85963 CDS NP_223481.1 15611830 890132 841348..841668 1 NC_000921.1 similar to H. pylori 26695 gene HP0824; thioredoxin 841668 trxA 890132 trxA Helicobacter pylori J99 thioredoxin NP_223481.1 841348 D 85963 CDS NP_223482.1 15611831 890127 841674..842609 1 NC_000921.1 similar to H. pylori 26695 gene HP0825; thioredoxin reductase 842609 trxB_1 890127 trxB_1 Helicobacter pylori J99 thioredoxin reductase NP_223482.1 841674 D 85963 CDS NP_223483.1 15611832 890131 842976..843797 1 NC_000921.1 similar to H. pylori 26695 gene HP0826; lipopolysaccharide biosynthesis protein 843797 890131 jhp0765 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223483.1 842976 D 85963 CDS NP_223484.1 15611833 890129 complement(844007..844255) 1 NC_000921.1 similar to H. pylori 26695 gene HP0827; hypothetical protein 844255 890129 jhp0766 Helicobacter pylori J99 hypothetical protein NP_223484.1 844007 R 85963 CDS NP_223485.1 15611834 890120 complement(844583..845263) 1 NC_000921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 845263 atpB 890120 atpB Helicobacter pylori J99 ATP synthase F0F1 subunit A NP_223485.1 844583 R 85963 CDS NP_223486.1 15611835 890128 complement(845385..846830) 1 NC_000921.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 846830 guaB 890128 guaB Helicobacter pylori J99 inosine 5'-monophosphate dehydrogenase NP_223486.1 845385 R 85963 CDS NP_223487.1 15611836 890125 complement(846840..848201) 1 NC_000921.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 848201 gatA 890125 gatA Helicobacter pylori J99 aspartyl/glutamyl-tRNA amidotransferase subunit A NP_223487.1 846840 R 85963 CDS NP_223488.1 15611837 890126 complement(848260..848850) 1 NC_000921.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 848850 coaE 890126 coaE Helicobacter pylori J99 dephospho-CoA kinase NP_223488.1 848260 R 85963 CDS NP_223489.1 15611838 890122 complement(848852..849640) 1 NC_000921.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 849640 speE 890122 speE Helicobacter pylori J99 spermidine synthase NP_223489.1 848852 R 85963 CDS NP_223490.1 15611839 890123 complement(849733..850623) 1 NC_000921.1 similar to H. pylori 26695 gene HP0833; hypothetical protein 850623 890123 jhp0772 Helicobacter pylori J99 hypothetical protein NP_223490.1 849733 R 85963 CDS NP_223491.1 15611840 890124 850700..852088 1 NC_000921.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 852088 engA 890124 engA Helicobacter pylori J99 GTP-binding protein EngA NP_223491.1 850700 D 85963 CDS NP_223492.1 15611841 890121 852229..852513 1 NC_000921.1 similar to H. pylori 26695 gene HP0835; DNA-binding protein HU 852513 890121 jhp0774 Helicobacter pylori J99 DNA-binding protein HU NP_223492.1 852229 D 85963 CDS NP_223493.1 15611842 890118 853193..853798 1 NC_000921.1 similar to H. pylori 26695 gene HP0836 and HP0837; hypothetical protein 853798 890118 jhp0775 Helicobacter pylori J99 hypothetical protein NP_223493.1 853193 D 85963 CDS NP_223494.1 15611843 890119 853818..854435 1 NC_000921.1 similar to H. pylori 26695 gene HP0838; hypothetical protein 854435 890119 jhp0776 Helicobacter pylori J99 hypothetical protein NP_223494.1 853818 D 85963 CDS NP_223495.1 15611844 890115 854432..856195 1 NC_000921.1 similar to H. pylori 26695 gene HP0839; hypothetical protein 856195 890115 jhp0777 Helicobacter pylori J99 hypothetical protein NP_223495.1 854432 D 85963 CDS NP_223496.1 15611845 890117 856199..857200 1 NC_000921.1 similar to H. pylori 26695 gene HP0840; sugar nucleotide biosynthesis protein 857200 890117 jhp0778 Helicobacter pylori J99 sugar nucleotide biosynthesis protein NP_223496.1 856199 D 85963 CDS NP_223497.1 15611846 890112 857197..858474 1 NC_000921.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 858474 dfp 890112 dfp Helicobacter pylori J99 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase NP_223497.1 857197 D 85963 CDS NP_223498.1 15611847 890116 858474..859211 1 NC_000921.1 similar to H. pylori 26695 gene HP0842; hypothetical protein 859211 890116 jhp0780 Helicobacter pylori J99 hypothetical protein NP_223498.1 858474 D 85963 CDS NP_223499.1 15611848 890113 complement(859321..859974) 1 NC_000921.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 859974 thiE 890113 thiE Helicobacter pylori J99 thiamine-phosphate pyrophosphorylase NP_223499.1 859321 R 85963 CDS NP_223500.1 15611849 890106 complement(859967..860776) 1 NC_000921.1 similar to H. pylori 26695 gene HP0844; phosphomethylpyrimidine kinase 860776 thiD 890106 thiD Helicobacter pylori J99 phosphomethylpyrimidine kinase NP_223500.1 859967 R 85963 CDS NP_223501.1 15611850 890114 complement(860773..861552) 1 NC_000921.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 861552 thiM 890114 thiM Helicobacter pylori J99 hydroxyethylthiazole kinase NP_223501.1 860773 R 85963 CDS NP_223502.1 15611851 890111 complement(861645..864272) 1 NC_000921.1 similar to H. pylori 26695 gene HP0846; type I restriction enzyme restriction subunit 864272 hsdR_2 890111 hsdR_2 Helicobacter pylori J99 type I restriction enzyme restriction subunit NP_223502.1 861645 R 85963 CDS NP_223503.1 15611852 890110 complement(864828..865451) 1 NC_000921.1 similar to H. pylori 26695 gene HP0848 and HP0849; type I restrictionenzyme (specificity subunit) 865451 hsdS_2 890110 hsdS_2 Helicobacter pylori J99 type I restrictionenzyme (specificity subunit) NP_223503.1 864828 R 85963 CDS NP_223504.1 15611853 890109 complement(865462..867048) 1 NC_000921.1 similar to H. pylori 26695 gene HP0850; type I restriction enzyme modification subunit 867048 hsdM_2 890109 hsdM_2 Helicobacter pylori J99 type I restriction enzyme modification subunit NP_223504.1 865462 R 85963 CDS NP_223505.1 15611854 890108 867227..867913 1 NC_000921.1 similar to H. pylori 26695 gene HP0851; hypothetical protein 867913 890108 jhp0787 Helicobacter pylori J99 hypothetical protein NP_223505.1 867227 D 85963 CDS NP_223506.1 15611855 890107 complement(867956..868897) 1 NC_000921.1 similar to H. pylori 26695 gene HP0852; hypothetical protein 868897 890107 jhp0788 Helicobacter pylori J99 hypothetical protein NP_223506.1 867956 R 85963 CDS NP_223507.1 15611856 890103 complement(868894..870495) 1 NC_000921.1 similar to H. pylori 26695 gene HP0853; ABC transporter ATP-binding protein 870495 890103 jhp0789 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_223507.1 868894 R 85963 CDS NP_223508.1 15611857 890104 870697..871674 1 NC_000921.1 similar to H. pylori 26695 gene HP0854; guanosine 5'-monophosphate oxidoreductase 871674 guaC 890104 guaC Helicobacter pylori J99 guanosine 5'-monophosphate oxidoreductase NP_223508.1 870697 D 85963 CDS NP_223509.1 15611858 890105 complement(871698..872276) 1 NC_000921.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 872276 gmhA 890105 gmhA Helicobacter pylori J99 phosphoheptose isomerase NP_223509.1 871698 R 85963 CDS NP_223510.1 15611859 890101 complement(872269..873660) 1 NC_000921.1 similar to H. pylori 26695 gene HP0858; ADP-D-glycero-D-mannoheptose synthase 873660 waaE 890101 waaE Helicobacter pylori J99 ADP-D-glycero-D-mannoheptose synthase NP_223510.1 872269 R 85963 CDS NP_223511.1 15611860 890102 complement(873657..874646) 1 NC_000921.1 similar to H. pylori 26695 gene HP0859; ADP-L-glycero-D-manno-heptose-6-epimerase 874646 gmhD 890102 gmhD Helicobacter pylori J99 ADP-L-glycero-D-manno-heptose-6-epimerase NP_223511.1 873657 R 85963 CDS NP_223512.1 15611861 890098 complement(874656..875180) 1 NC_000921.1 similar to H. pylori 26695 gene HP0860; hypothetical protein 875180 890098 jhp0794 Helicobacter pylori J99 hypothetical protein NP_223512.1 874656 R 85963 CDS NP_223513.1 15611862 890100 complement(875167..875904) 1 NC_000921.1 similar to H. pylori 26695 gene HP0861; hypothetical protein 875904 890100 jhp0795 Helicobacter pylori J99 hypothetical protein NP_223513.1 875167 R 85963 CDS NP_223514.1 15611863 890099 complement(875895..876566) 1 NC_000921.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 876566 890099 jhp0796 Helicobacter pylori J99 pantothenate kinase NP_223514.1 875895 R 85963 CDS NP_223515.1 15611864 890094 complement(876571..878196) 1 NC_000921.1 similar to H. pylori 26695 gene HP0863; hypothetical protein 878196 890094 jhp0797 Helicobacter pylori J99 hypothetical protein NP_223515.1 876571 R 85963 CDS NP_223516.1 15611865 890092 complement(878201..878857) 1 NC_000921.1 similar to H. pylori 26695 gene HP0864; hypothetical protein 878857 890092 jhp0798 Helicobacter pylori J99 hypothetical protein NP_223516.1 878201 R 85963 CDS NP_223517.1 15611866 890097 complement(878854..879291) 1 NC_000921.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 879291 dut 890097 dut Helicobacter pylori J99 deoxyuridine 5'-triphosphate nucleotidohydrolase NP_223517.1 878854 R 85963 CDS NP_223518.1 15611867 890096 complement(879281..879775) 1 NC_000921.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 879775 greA 890096 greA Helicobacter pylori J99 transcription elongation factor GreA NP_223518.1 879281 R 85963 CDS NP_223519.1 15611868 890095 complement(879816..880898) 1 NC_000921.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase 880898 lpxB 890095 lpxB Helicobacter pylori J99 ipid-A-disaccharide synthase NP_223519.1 879816 R 85963 CDS NP_223520.1 15611869 890090 complement(880898..881359) 1 NC_000921.1 similar to H. pylori 26695 gene HP0868; hypothetical protein 881359 890090 jhp0802 Helicobacter pylori J99 hypothetical protein NP_223520.1 880898 R 85963 CDS NP_223521.1 15611870 890093 complement(881366..881719) 1 NC_000921.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 881719 hypA 890093 hypA Helicobacter pylori J99 hydrogenase nickel incorporation protein NP_223521.1 881366 R 85963 CDS NP_223522.1 15611871 890091 complement(881778..883934) 1 NC_000921.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 883934 flgE 890091 flgE Helicobacter pylori J99 flagellar hook protein FlgE NP_223522.1 881778 R 85963 CDS NP_223523.1 15611872 890088 complement(884143..884877) 1 NC_000921.1 similar to H. pylori 26695 gene HP0871; CDP-diacylglycerol pyrophosphatase 884877 cdh 890088 cdh Helicobacter pylori J99 CDP-diacylglycerol pyrophosphatase NP_223523.1 884143 R 85963 CDS NP_223524.1 15611873 890089 885154..885483 1 NC_000921.1 similar to H. pylori 26695 gene HP0872; alkylphosphonate uptake protein 885483 phnA 890089 phnA Helicobacter pylori J99 alkylphosphonate uptake protein NP_223524.1 885154 D 85963 CDS NP_223525.1 15611874 890081 complement(885541..885756) 1 NC_000921.1 similar to H. pylori 26695 gene HP0873; hypothetical protein 885756 890081 jhp0807 Helicobacter pylori J99 hypothetical protein NP_223525.1 885541 R 85963 CDS NP_223526.1 15611875 890087 complement(885841..886719) 1 NC_000921.1 similar to H. pylori 26695 gene HP0874; hypothetical protein 886719 890087 jhp0808 Helicobacter pylori J99 hypothetical protein NP_223526.1 885841 R 85963 CDS NP_223527.1 15611876 890086 complement(886867..888384) 1 NC_000921.1 similar to H. pylori 26695 gene HP0875; catalase 888384 katA 890086 katA Helicobacter pylori J99 catalase NP_223527.1 886867 R 85963 CDS NP_223528.1 15611877 890085 888708..891083 1 NC_000921.1 similar to H. pylori 26695 gene HP0876; IRON-regulated outer membrane protein 891083 frpB_1 890085 frpB_1 Helicobacter pylori J99 IRON-regulated outer membrane protein NP_223528.1 888708 D 85963 CDS NP_223529.1 15611878 890084 complement(891084..891557) 1 NC_000921.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 891557 ruvC 890084 ruvC Helicobacter pylori J99 Holliday junction resolvase NP_223529.1 891084 R 85963 CDS NP_223530.1 15611879 890083 891689..892420 1 NC_000921.1 similar to H. pylori 26695 gene HP0878 and HP0879; hypothetical protein 892420 890083 jhp0812 Helicobacter pylori J99 hypothetical protein NP_223530.1 891689 D 85963 CDS NP_223531.1 15611880 890082 complement(893499..893966) 1 NC_000921.1 hypothetical protein 893966 890082 jhp0813 Helicobacter pylori J99 hypothetical protein NP_223531.1 893499 R 85963 CDS NP_223532.1 15611881 890079 complement(893875..894228) 1 NC_000921.1 hypothetical protein 894228 890079 jhp0814 Helicobacter pylori J99 hypothetical protein NP_223532.1 893875 R 85963 CDS NP_223533.1 15611882 890076 complement(894351..894902) 1 NC_000921.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 894902 ruvA 890076 ruvA Helicobacter pylori J99 Holliday junction DNA helicase RuvA NP_223533.1 894351 R 85963 CDS NP_223534.1 15611883 890078 complement(894929..896773) 1 NC_000921.1 similar to H. pylori 26695 gene HP0884; hypothetical protein 896773 890078 jhp0816 Helicobacter pylori J99 hypothetical protein NP_223534.1 894929 R 85963 CDS NP_223535.1 15611884 890074 896944..898326 1 NC_000921.1 similar to H. pylori 26695 gene HP0885; hypothetical protein 898326 890074 jhp0817 Helicobacter pylori J99 hypothetical protein NP_223535.1 896944 D 85963 CDS NP_223536.1 15611885 890077 898327..899724 1 NC_000921.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 899724 cysS 890077 cysS Helicobacter pylori J99 cysteinyl-tRNA synthetase NP_223536.1 898327 D 85963 CDS NP_223537.1 15611886 890075 900011..903877 1 NC_000921.1 similar to H. pylori 26695 gene HP0887; vacuolating cytotoxin 903877 vacA 890075 vacA Helicobacter pylori J99 vacuolating cytotoxin NP_223537.1 900011 D 85963 CDS NP_223538.1 15611887 890073 complement(903994..905115) 1 NC_000921.1 lipopolysaccharide biosynthesis protein 905115 890073 jhp0820 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223538.1 903994 R 85963 CDS NP_223539.1 15611888 890072 complement(905179..905946) 1 NC_000921.1 similar to H. pylori 26695 gene HP0888; IRON(III) dicitrate transport system ATP-binding protein 905946 fecE 890072 fecE Helicobacter pylori J99 IRON(III) dicitrate transport system ATP-binding protein NP_223539.1 905179 R 85963 CDS NP_223540.1 15611889 890065 complement(905946..906926) 1 NC_000921.1 similar to H. pylori 26695 gene HP0889; iron ABC transporter permease 906926 fecD 890065 fecD Helicobacter pylori J99 iron ABC transporter permease NP_223540.1 905946 R 85963 CDS NP_223541.1 15611890 890071 complement(906919..907734) 1 NC_000921.1 similar to H. pylori 26695 gene HP0890; hypothetical protein 907734 890071 jhp0823 Helicobacter pylori J99 hypothetical protein NP_223541.1 906919 R 85963 CDS NP_223542.1 15611891 890070 907916..908440 1 NC_000921.1 similar to H. pylori 26695 gene HP0891; hypothetical protein 908440 890070 jhp0824 Helicobacter pylori J99 hypothetical protein NP_223542.1 907916 D 85963 CDS NP_223543.1 15611892 890066 complement(908515..908817) 1 NC_000921.1 hypothetical protein 908817 890066 jhp0825 Helicobacter pylori J99 hypothetical protein NP_223543.1 908515 R 85963 CDS NP_223544.1 15611893 890069 complement(908966..910294) 1 NC_000921.1 IS606 transposase 910294 tnpB 890069 tnpB Helicobacter pylori J99 IS606 transposase NP_223544.1 908966 R 85963 CDS NP_223545.1 15611894 890063 910322..910516 1 NC_000921.1 IS606 transposase 910516 tnpA 890063 tnpA Helicobacter pylori J99 IS606 transposase NP_223545.1 910322 D 85963 CDS NP_223546.1 15611895 890064 complement(910638..910844) 1 NC_000921.1 hypothetical protein 910844 890064 jhp0828 Helicobacter pylori J99 hypothetical protein NP_223546.1 910638 R 85963 CDS NP_223547.1 15611896 890059 complement(910912..911058) 1 NC_000921.1 hypothetical protein 911058 890059 jhp0829 Helicobacter pylori J99 hypothetical protein NP_223547.1 910912 R 85963 CDS NP_223548.1 15611897 890061 complement(911422..911673) 1 NC_000921.1 hypothetical protein 911673 890061 jhp0830 Helicobacter pylori J99 hypothetical protein NP_223548.1 911422 R 85963 CDS NP_223549.1 15611898 890062 complement(911721..911993) 1 NC_000921.1 similar to H. pylori 26695 gene HP0892; hypothetical protein 911993 890062 jhp0831 Helicobacter pylori J99 hypothetical protein NP_223549.1 911721 R 85963 CDS NP_223550.1 15611899 890060 complement(912007..912294) 1 NC_000921.1 similar to H. pylori 26695 gene HP0893; hypothetical protein 912294 890060 jhp0832 Helicobacter pylori J99 hypothetical protein NP_223550.1 912007 R 85963 CDS NP_223551.1 15611900 890058 complement(912790..915024) 1 NC_000921.1 similar to H. pylori 26695 gene HP1243; hypothetical protein 915024 babA 890058 babA Helicobacter pylori J99 hypothetical protein NP_223551.1 912790 R 85963 CDS NP_223552.1 15611901 890056 complement(916021..916431) 1 NC_000921.1 hypothetical protein 916431 890056 jhp0834 Helicobacter pylori J99 hypothetical protein NP_223552.1 916021 R 85963 CDS NP_223553.1 15611902 890057 complement(916398..917510) 1 NC_000921.1 similar to H. pylori 26695 gene HP0898; hydrogenase expression/formation protein 917510 hypD 890057 hypD Helicobacter pylori J99 hydrogenase expression/formation protein NP_223553.1 916398 R 85963 CDS NP_223554.1 15611903 890052 complement(917525..917761) 1 NC_000921.1 similar to H. pylori 26695 gene HP0899; hydrogenase expression/formation protein 917761 hypC 890052 hypC Helicobacter pylori J99 hydrogenase expression/formation protein NP_223554.1 917525 R 85963 CDS NP_223555.1 15611904 890055 complement(917761..918489) 1 NC_000921.1 similar to H. pylori 26695 gene HP0900; hydrogenase expression/formation protein 918489 hypB 890055 hypB Helicobacter pylori J99 hydrogenase expression/formation protein NP_223555.1 917761 R 85963 CDS NP_223556.1 15611905 890053 complement(918602..918730) 1 NC_000921.1 similar to H. pylori 26695 gene HP0901; hypothetical protein 918730 890053 jhp0838 Helicobacter pylori J99 hypothetical protein NP_223556.1 918602 R 85963 CDS NP_223557.1 15611906 890054 complement(918741..919040) 1 NC_000921.1 similar to H. pylori 26695 gene HP0902; hypothetical protein 919040 890054 jhp0839 Helicobacter pylori J99 hypothetical protein NP_223557.1 918741 R 85963 CDS NP_223558.1 15611907 890045 complement(919040..920251) 1 NC_000921.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 920251 ackA 890045 ackA Helicobacter pylori J99 acetate kinase NP_223558.1 919040 R 85963 CDS NP_223559.1 15611908 890051 complement(920263..921822) 1 NC_000921.1 similar to H. pylori 26695 gene HP0904 and HP0905; phosphotransacetylase 921822 pta 890051 pta Helicobacter pylori J99 phosphotransacetylase NP_223559.1 920263 R 85963 CDS NP_223560.1 15611909 890050 922003..923577 1 NC_000921.1 similar to H. pylori 26695 gene HP0906; hypothetical protein 923577 890050 jhp0842 Helicobacter pylori J99 hypothetical protein NP_223560.1 922003 D 85963 CDS NP_223561.1 15611910 890049 923628..924719 1 NC_000921.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 924719 flgD 890049 flgD Helicobacter pylori J99 flagellar basal body rod modification protein NP_223561.1 923628 D 85963 CDS NP_223562.1 15611911 890048 924716..926533 1 NC_000921.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 926533 flgE 890048 flgE Helicobacter pylori J99 flagellar hook protein FlgE NP_223562.1 924716 D 85963 CDS NP_223563.1 15611912 890047 926585..927166 1 NC_000921.1 similar to H. pylori 26695 gene HP0909; hypothetical protein 927166 890047 jhp0845 Helicobacter pylori J99 hypothetical protein NP_223563.1 926585 D 85963 CDS NP_223564.1 15611913 890040 927176..928321 1 NC_000921.1 similar to H. pylori 26695 gene HP0910; type II DNA modification (methyltransferase 928321 890040 jhp0846 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_223564.1 927176 D 85963 CDS NP_223565.1 15611914 890046 928330..930360 1 NC_000921.1 similar to H. pylori 26695 gene HP0911; ATP-dependent helicase 930360 890046 jhp0847 Helicobacter pylori J99 ATP-dependent helicase NP_223565.1 928330 D 85963 CDS NP_223566.1 15611915 890044 931524..933086 1 NC_000921.1 similar to H. pylori 26695 gene HP0912; Outer membrane protein/porin 933086 hopC 890044 hopC Helicobacter pylori J99 Outer membrane protein/porin NP_223566.1 931524 D 85963 CDS NP_223567.1 15611916 890042 933108..934691 1 NC_000921.1 similar to H. pylori 26695 gene HP0913; Outer membrane protein/porin 934691 hopB 890042 hopB Helicobacter pylori J99 Outer membrane protein/porin NP_223567.1 933108 D 85963 CDS NP_223568.1 15611917 890043 complement(935476..937020) 1 NC_000921.1 similar to H. pylori 26695 gene HP0914; hypothetical protein 937020 890043 jhp0850 Helicobacter pylori J99 hypothetical protein NP_223568.1 935476 R 85963 CDS NP_223569.1 15611918 890041 complement(937358..939805) 1 NC_000921.1 similar to H. pylori 26695 gene HP0915 and HP0916; IRON-regulated outer membrane protein 939805 frpB_2 890041 frpB_2 Helicobacter pylori J99 IRON-regulated outer membrane protein NP_223569.1 937358 R 85963 CDS NP_223570.1 15611919 890037 complement(939981..940412) 1 NC_000921.1 similar to H. pylori 26695 gene HP0918; hypothetical protein 940412 890037 jhp0852 Helicobacter pylori J99 hypothetical protein NP_223570.1 939981 R 85963 CDS NP_223571.1 15611920 890029 complement(940417..943674) 1 NC_000921.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 943674 carB 890029 carB Helicobacter pylori J99 carbamoyl phosphate synthase large subunit NP_223571.1 940417 R 85963 CDS NP_223572.1 15611921 890039 complement(943774..944466) 1 NC_000921.1 similar to H. pylori 26695 gene HP0920; hypothetical protein 944466 890039 jhp0854 Helicobacter pylori J99 hypothetical protein NP_223572.1 943774 R 85963 CDS NP_223573.1 15611922 890038 944612..945610 1 NC_000921.1 similar to H. pylori 26695 gene HP0921; glyceraldehyde 3-phosphate dehydrogenase 945610 gap_1 890038 gap_1 Helicobacter pylori J99 glyceraldehyde 3-phosphate dehydrogenase NP_223573.1 944612 D 85963 CDS NP_223574.1 15611923 890036 945691..952890 1 NC_000921.1 similar to H. pylori 26695 gene HP0922; vacuolating cytotoxin (VacA) paralog 952890 890036 jhp0856 Helicobacter pylori J99 vacuolating cytotoxin (VacA) paralog NP_223574.1 945691 D 85963 CDS NP_223575.1 15611924 890035 952943..954043 1 NC_000921.1 similar to H. pylori 26695 gene HP0923; hypothetical protein 954043 890035 jhp0857 Helicobacter pylori J99 hypothetical protein NP_223575.1 952943 D 85963 CDS NP_223576.1 15611925 890034 complement(954113..954319) 1 NC_000921.1 similar to H. pylori 26695 gene HP0924; hypothetical protein 954319 890034 jhp0858 Helicobacter pylori J99 hypothetical protein NP_223576.1 954113 R 85963 CDS NP_223577.1 15611926 890033 954488..955069 1 NC_000921.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 955069 recR 890033 recR Helicobacter pylori J99 recombination protein RecR NP_223577.1 954488 D 85963 CDS NP_223578.1 15611927 890027 955066..956211 1 NC_000921.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 956211 truD 890027 truD Helicobacter pylori J99 tRNA pseudouridine synthase D NP_223578.1 955066 D 85963 CDS NP_223579.1 15611928 890025 956198..957130 1 NC_000921.1 metalloprotease; heat shock protein HtpX 957130 htpX 890025 htpX Helicobacter pylori J99 heat shock protein HtpX NP_223579.1 956198 D 85963 CDS NP_223580.1 15611929 890032 957131..957343 1 NC_000921.1 similar to H. pylori 26695 gene HP0928; GTP cyclohydrolase I 957343 folE_1 890032 folE_1 Helicobacter pylori J99 GTP cyclohydrolase I NP_223580.1 957131 D 85963 CDS NP_223581.1 15611930 890024 957598..958140 1 NC_000921.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 958140 folE 890024 folE Helicobacter pylori J99 GTP cyclohydrolase I NP_223581.1 957598 D 85963 CDS NP_223582.1 15611931 890030 958156..959067 1 NC_000921.1 similar to H. pylori 26695 gene HP0929; geranyltranstransferase 959067 ispA 890030 ispA Helicobacter pylori J99 geranyltranstransferase NP_223582.1 958156 D 85963 CDS NP_223583.1 15611932 890031 959064..959867 1 NC_000921.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 959867 surE 890031 surE Helicobacter pylori J99 stationary phase survival protein SurE NP_223583.1 959064 D 85963 CDS NP_223584.1 15611933 890026 959864..960523 1 NC_000921.1 similar to H. pylori 26695 gene HP0931 and HP0932; hypothetical protein 960523 890026 jhp0866 Helicobacter pylori J99 hypothetical protein NP_223584.1 959864 D 85963 CDS NP_223585.1 15611934 890028 960525..961127 1 NC_000921.1 similar to H. pylori 26695 gene HP0933; hypothetical protein 961127 890028 jhp0867 Helicobacter pylori J99 hypothetical protein NP_223585.1 960525 D 85963 CDS NP_223586.1 15611935 889179 961124..961879 1 NC_000921.1 similar to H. pylori 26695 gene HP0934; hypothetical protein 961879 889179 jhp0868 Helicobacter pylori J99 hypothetical protein NP_223586.1 961124 D 85963 CDS NP_223587.1 15611936 890283 961971..962456 1 NC_000921.1 similar to H. pylori 26695 gene HP0935; hypothetical protein 962456 890283 jhp0869 Helicobacter pylori J99 hypothetical protein NP_223587.1 961971 D 85963 CDS NP_223588.1 15611937 889515 962682..964688 1 NC_000921.1 hypothetical protein 964688 889515 jhp0870 Helicobacter pylori J99 hypothetical protein NP_223588.1 962682 D 85963 CDS NP_223589.1 15611938 889519 complement(965126..966484) 1 NC_000921.1 similar to H. pylori 26695 gene HP0936; proline/betaine transporter 966484 proP 889519 proP Helicobacter pylori J99 proline/betaine transporter NP_223589.1 965126 R 85963 CDS NP_223590.1 15611939 889514 complement(966767..967591) 1 NC_000921.1 similar to H. pylori 26695 gene HP0937; hypothetical protein 967591 889514 jhp0872 Helicobacter pylori J99 hypothetical protein NP_223590.1 966767 R 85963 CDS NP_223591.1 15611940 889516 complement(967598..968473) 1 NC_000921.1 similar to H. pylori 26695 gene HP0938; hypothetical protein 968473 889516 jhp0873 Helicobacter pylori J99 hypothetical protein NP_223591.1 967598 R 85963 CDS NP_223592.1 15611941 889517 complement(968545..969258) 1 NC_000921.1 similar to H. pylori 26695 gene HP0939; amino acid ABC transporter permease 969258 889517 jhp0874 Helicobacter pylori J99 amino acid ABC transporter permease NP_223592.1 968545 R 85963 CDS NP_223593.1 15611942 889531 complement(969242..970015) 1 NC_000921.1 similar to H. pylori 26695 gene HP0940; amino acid ABC transporter 970015 889531 jhp0875 Helicobacter pylori J99 amino acid ABC transporter NP_223593.1 969242 R 85963 CDS NP_223594.1 15611943 889518 complement(970081..971214) 1 NC_000921.1 similar to H. pylori 26695 gene HP0941; alanine racemase 971214 alr 889518 alr Helicobacter pylori J99 alanine racemase NP_223594.1 970081 R 85963 CDS NP_223595.1 15611944 889520 complement(971221..972573) 1 NC_000921.1 similar to H. pylori 26695 gene HP0942; sodium/alanine symporter 972573 889520 jhp0877 Helicobacter pylori J99 sodium/alanine symporter NP_223595.1 971221 R 85963 CDS NP_223596.1 15611945 889521 complement(972614..973846) 1 NC_000921.1 similar to H. pylori 26695 gene HP0943; D-amino acid dehydrogenase 973846 dadA 889521 dadA Helicobacter pylori J99 D-amino acid dehydrogenase NP_223596.1 972614 R 85963 CDS NP_223597.1 15611946 889522 complement(973869..974246) 1 NC_000921.1 similar to H. pylori 26695 gene HP0944; hypothetical protein 974246 889522 jhp0879 Helicobacter pylori J99 hypothetical protein NP_223597.1 973869 R 85963 CDS NP_223598.1 15611947 889523 975154..976635 1 NC_000921.1 similar to H. pylori 26695 gene HP0946; hypothetical protein 976635 889523 jhp0880 Helicobacter pylori J99 hypothetical protein NP_223598.1 975154 D 85963 CDS NP_223599.1 15611948 889524 976960..977322 1 NC_000921.1 similar to H. pylori 26695 gene HP0947; hypothetical protein 977322 889524 jhp0881 Helicobacter pylori J99 hypothetical protein NP_223599.1 976960 D 85963 CDS NP_223600.1 15611949 889537 complement(977734..978747) 1 NC_000921.1 similar to H. pylori 26695 gene HP0948; hypothetical protein 978747 889537 jhp0882 Helicobacter pylori J99 hypothetical protein NP_223600.1 977734 R 85963 CDS NP_223601.1 15611950 889525 complement(978757..979209) 1 NC_000921.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 979209 889525 jhp0883 Helicobacter pylori J99 rRNA large subunit methyltransferase NP_223601.1 978757 R 85963 CDS NP_223602.1 15611951 889526 complement(979223..980092) 1 NC_000921.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 980092 accD 889526 accD Helicobacter pylori J99 acetyl-CoA carboxylase subunit beta NP_223602.1 979223 R 85963 CDS NP_223603.1 15611952 889527 980173..980787 1 NC_000921.1 similar to H. pylori 26695 gene HP0951; recombination protein RecO 980787 889527 jhp0885 Helicobacter pylori J99 recombination protein RecO NP_223603.1 980173 D 85963 CDS NP_223604.1 15611953 889528 980798..981454 1 NC_000921.1 similar to H. pylori 26695 gene HP0952; hypothetical protein 981454 889528 jhp0886 Helicobacter pylori J99 hypothetical protein NP_223604.1 980798 D 85963 CDS NP_223605.1 15611954 889529 complement(981457..982023) 1 NC_000921.1 similar to H. pylori 26695 gene HP0953; hypothetical protein 982023 889529 jhp0887 Helicobacter pylori J99 hypothetical protein NP_223605.1 981457 R 85963 CDS NP_223606.1 15611955 889563 complement(982088..982720) 1 NC_000921.1 similar to H. pylori 26695 gene HP0954; aldehyde dehydrogenase 982720 889563 jhp0888 Helicobacter pylori J99 aldehyde dehydrogenase NP_223606.1 982088 R 85963 CDS NP_223607.1 15611956 889530 complement(982720..983571) 1 NC_000921.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 983571 lgt 889530 lgt Helicobacter pylori J99 prolipoprotein diacylglyceryl transferase NP_223607.1 982720 R 85963 CDS NP_223608.1 15611957 889532 complement(983580..984308) 1 NC_000921.1 similar to H. pylori 26695 gene HP0956; hypothetical protein 984308 889532 jhp0890 Helicobacter pylori J99 hypothetical protein NP_223608.1 983580 R 85963 CDS NP_223609.1 15611958 889533 complement(984326..985507) 1 NC_000921.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 985507 waaA 889533 waaA Helicobacter pylori J99 3-deoxy-D-manno-octulosonic-acid transferase NP_223609.1 984326 R 85963 CDS NP_223610.1 15611959 889534 complement(985508..986311) 1 NC_000921.1 similar to H. pylori 26695 gene HP0958; hypothetical protein 986311 889534 jhp0892 Helicobacter pylori J99 hypothetical protein NP_223610.1 985508 R 85963 CDS NP_223611.1 15611960 889546 complement(986321..987052) 1 NC_000921.1 similar to H. pylori 26695 gene HP0959; hypothetical protein 987052 889546 jhp0893 Helicobacter pylori J99 hypothetical protein NP_223611.1 986321 R 85963 CDS NP_223612.1 15611961 889535 complement(987054..987950) 1 NC_000921.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 987950 glyQ 889535 glyQ Helicobacter pylori J99 glycyl-tRNA synthetase subunit alpha NP_223612.1 987054 R 85963 CDS NP_223613.1 15611962 889536 complement(987964..988902) 1 NC_000921.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 988902 gpsA 889536 gpsA Helicobacter pylori J99 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_223613.1 987964 R 85963 CDS NP_223614.1 15611963 889538 complement(989179..989871) 1 NC_000921.1 hypothetical protein 989871 889538 jhp0896 Helicobacter pylori J99 hypothetical protein NP_223614.1 989179 R 85963 CDS NP_223615.1 15611964 889539 complement(990227..990907) 1 NC_000921.1 similar to H. pylori 26695 gene HP0963; hypothetical protein 990907 889539 jhp0897 Helicobacter pylori J99 hypothetical protein NP_223615.1 990227 R 85963 CDS NP_223616.1 15611965 889540 complement(990904..991638) 1 NC_000921.1 similar to H. pylori 26695 gene HP0964; hypothetical protein 991638 889540 jhp0898 Helicobacter pylori J99 hypothetical protein NP_223616.1 990904 R 85963 CDS NP_223617.1 15611966 889541 complement(991704..993206) 1 NC_000921.1 similar to H. pylori 26695 gene HP0964 and HP0965; hypothetical protein 993206 889541 jhp0899 Helicobacter pylori J99 hypothetical protein NP_223617.1 991704 R 85963 CDS NP_223618.1 15611967 889542 complement(993206..994228) 1 NC_000921.1 similar to H. pylori 26695 gene HP0966; hypothetical protein 994228 889542 jhp0900 Helicobacter pylori J99 hypothetical protein NP_223618.1 993206 R 85963 CDS NP_223619.1 15611968 889543 complement(994288..994788) 1 NC_000921.1 similar to H. pylori 26695 gene HP0966; hypothetical protein 994788 889543 jhp0901 Helicobacter pylori J99 hypothetical protein NP_223619.1 994288 R 85963 CDS NP_223620.1 15611969 889544 complement(995162..995443) 1 NC_000921.1 similar to H. pylori 26695 gene HP0968; hypothetical protein 995443 889544 jhp0902 Helicobacter pylori J99 hypothetical protein NP_223620.1 995162 R 85963 CDS NP_223621.1 15611970 889550 complement(995459..998518) 1 NC_000921.1 similar to H. pylori 26695 gene HP0969; cation efflux system protein 998518 czcA_1 889550 czcA_1 Helicobacter pylori J99 cation efflux system protein NP_223621.1 995459 R 85963 CDS NP_223622.1 15611971 889545 complement(998518..999597) 1 NC_000921.1 similar to H. pylori 26695 gene HP0970; cation efflux system protein 999597 czcB_1 889545 czcB_1 Helicobacter pylori J99 cation efflux system protein NP_223622.1 998518 R 85963 CDS NP_223623.1 15611972 889547 complement(999594..1000889) 1 NC_000921.1 similar to H. pylori 26695 gene HP0971; hypothetical protein 1000889 889547 jhp0905 Helicobacter pylori J99 hypothetical protein NP_223623.1 999594 R 85963 CDS NP_223624.1 15611973 889549 complement(1000879..1002984) 1 NC_000921.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1002984 glyS 889549 glyS Helicobacter pylori J99 glycyl-tRNA synthetase subunit beta NP_223624.1 1000879 R 85963 CDS NP_223625.1 15611974 889554 1003101..1004189 1 NC_000921.1 similar to H. pylori 26695 gene HP0973; hypothetical protein 1004189 889554 jhp0907 Helicobacter pylori J99 hypothetical protein NP_223625.1 1003101 D 85963 CDS NP_223626.1 15611975 889548 1004202..1005677 1 NC_000921.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1005677 pgm 889548 pgm Helicobacter pylori J99 phosphoglyceromutase NP_223626.1 1004202 D 85963 CDS NP_223627.1 15611976 889551 1005692..1005973 1 NC_000921.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1005973 gatC 889551 gatC Helicobacter pylori J99 aspartyl/glutamyl-tRNA amidotransferase subunit C NP_223627.1 1005692 D 85963 CDS NP_223628.1 15611977 889552 complement(1006070..1007389) 1 NC_000921.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1007389 bioA 889552 bioA Helicobacter pylori J99 adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_223628.1 1006070 R 85963 CDS NP_223629.1 15611978 889571 1007519..1008982 1 NC_000921.1 similar to H. pylori 26695 gene HP0977; hypothetical protein 1008982 889571 jhp0911 Helicobacter pylori J99 hypothetical protein NP_223629.1 1007519 D 85963 CDS NP_223630.1 15611979 889553 1008998..1010479 1 NC_000921.1 similar to H. pylori 26695 gene HP0978; septum formation protein 1010479 ftsA 889553 ftsA Helicobacter pylori J99 septum formation protein NP_223630.1 1008998 D 85963 CDS NP_223631.1 15611980 889557 1010607..1011764 1 NC_000921.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1011764 ftsZ 889557 ftsZ Helicobacter pylori J99 cell division protein FtsZ NP_223631.1 1010607 D 85963 CDS NP_223632.1 15611981 889555 complement(1012090..1013325) 1 NC_000921.1 hypothetical protein 1013325 889555 jhp0914 Helicobacter pylori J99 hypothetical protein NP_223632.1 1012090 R 85963 CDS NP_223633.1 15611982 889556 complement(1013672..1014496) 1 NC_000921.1 similar to H. pylori 26695 gene HP0983; hypothetical protein 1014496 889556 jhp0915 Helicobacter pylori J99 hypothetical protein NP_223633.1 1013672 R 85963 CDS NP_223634.1 15611983 889558 complement(1014636..1014830) 1 NC_000921.1 hypothetical protein 1014830 889558 jhp0916 Helicobacter pylori J99 hypothetical protein NP_223634.1 1014636 R 85963 CDS NP_223635.1 15611984 889559 1015042..1016469 1 NC_000921.1 DNA transfer protein 1016469 virB4_2 889559 virB4_2 Helicobacter pylori J99 DNA transfer protein NP_223635.1 1015042 D 85963 CDS NP_223636.1 15611985 889560 1016457..1016879 1 NC_000921.1 DNA transfer protein 1016879 virB4_3 889560 virB4_3 Helicobacter pylori J99 DNA transfer protein NP_223636.1 1016457 D 85963 CDS NP_223637.1 15611986 889561 1016916..1018193 1 NC_000921.1 topoisomerase I 1018193 topA_2 889561 topA_2 Helicobacter pylori J99 topoisomerase I NP_223637.1 1016916 D 85963 CDS NP_223638.1 15611987 889562 1018568..1018849 1 NC_000921.1 hypothetical protein 1018849 889562 jhp0920 Helicobacter pylori J99 hypothetical protein NP_223638.1 1018568 D 85963 CDS NP_223639.1 15611988 889572 1018979..1019965 1 NC_000921.1 hypothetical protein 1019965 889572 jhp0921 Helicobacter pylori J99 hypothetical protein NP_223639.1 1018979 D 85963 CDS NP_223640.1 15612561 889322 join(1019965..1020471,1020473..1021501) 1 NC_000921.1 conjugal plasmid transfer system protein 1021501 889322 jhp0922m Helicobacter pylori J99 conjugal plasmid transfer system protein NP_223640.1 1019965 D 85963 CDS NP_223641.1 15611989 889564 1021498..1022304 1 NC_000921.1 hypothetical protein 1022304 889564 jhp0924 Helicobacter pylori J99 hypothetical protein NP_223641.1 1021498 D 85963 CDS NP_223642.1 15611990 889565 complement(1021962..1022549) 1 NC_000921.1 hypothetical protein 1022549 889565 jhp0925 Helicobacter pylori J99 hypothetical protein NP_223642.1 1021962 R 85963 CDS NP_223643.1 15611991 889568 complement(1022556..1023572) 1 NC_000921.1 hypothetical protein 1023572 889568 jhp0926 Helicobacter pylori J99 hypothetical protein NP_223643.1 1022556 R 85963 CDS NP_223644.1 15611992 889566 1023777..1025174 1 NC_000921.1 hypothetical protein 1025174 889566 jhp0927 Helicobacter pylori J99 hypothetical protein NP_223644.1 1023777 D 85963 CDS NP_223645.1 15611993 889567 1025324..1032019 1 NC_000921.1 hypothetical protein 1032019 889567 jhp0928 Helicobacter pylori J99 hypothetical protein NP_223645.1 1025324 D 85963 CDS NP_223646.1 15611994 889570 1032025..1032477 1 NC_000921.1 hypothetical protein 1032477 889570 jhp0929 Helicobacter pylori J99 hypothetical protein NP_223646.1 1032025 D 85963 CDS NP_223647.1 15611995 889573 1032591..1032833 1 NC_000921.1 hypothetical protein 1032833 889573 jhp0930 Helicobacter pylori J99 hypothetical protein NP_223647.1 1032591 D 85963 CDS NP_223648.1 15611996 889569 1032846..1034906 1 NC_000921.1 topoisomerase I 1034906 topA_3 889569 topA_3 Helicobacter pylori J99 topoisomerase I NP_223648.1 1032846 D 85963 CDS NP_223649.1 15611997 889579 1034961..1035431 1 NC_000921.1 hypothetical protein 1035431 889579 jhp0932 Helicobacter pylori J99 hypothetical protein NP_223649.1 1034961 D 85963 CDS NP_223650.1 15611998 889577 1035401..1036204 1 NC_000921.1 hypothetical protein 1036204 889577 jhp0933 Helicobacter pylori J99 hypothetical protein NP_223650.1 1035401 D 85963 CDS NP_223651.1 15611999 889574 complement(1036277..1037296) 1 NC_000921.1 hypothetical protein 1037296 889574 jhp0934 Helicobacter pylori J99 hypothetical protein NP_223651.1 1036277 R 85963 CDS NP_223652.1 15612000 889575 complement(1037343..1037885) 1 NC_000921.1 hypothetical protein 1037885 889575 jhp0935 Helicobacter pylori J99 hypothetical protein NP_223652.1 1037343 R 85963 CDS NP_223653.1 15612001 889584 1038083..1038616 1 NC_000921.1 hypothetical protein 1038616 889584 jhp0936 Helicobacter pylori J99 hypothetical protein NP_223653.1 1038083 D 85963 CDS NP_223654.1 15612002 889589 1038613..1039878 1 NC_000921.1 hypothetical protein 1039878 889589 jhp0937 Helicobacter pylori J99 hypothetical protein NP_223654.1 1038613 D 85963 CDS NP_223655.1 15612003 889576 1039890..1041140 1 NC_000921.1 similar to H. pylori 26695 gene HP0990; hypothetical protein 1041140 889576 jhp0938 Helicobacter pylori J99 hypothetical protein NP_223655.1 1039890 D 85963 CDS NP_223656.1 15612004 889580 complement(1041145..1042158) 1 NC_000921.1 similar to H. pylori 26695 gene HP0991; hypothetical protein 1042158 889580 jhp0939 Helicobacter pylori J99 hypothetical protein NP_223656.1 1041145 R 85963 CDS NP_223657.1 15612005 889581 1042390..1043367 1 NC_000921.1 hypothetical protein 1043367 889581 jhp0940 Helicobacter pylori J99 hypothetical protein NP_223657.1 1042390 D 85963 CDS NP_223658.1 15612006 889582 complement(1043684..1044679) 1 NC_000921.1 similar to H. pylori 26695 gene HP0995; integrase/recombinase (XERCD family) 1044679 889582 jhp0941 Helicobacter pylori J99 integrase/recombinase (XERCD family) NP_223658.1 1043684 R 85963 CDS NP_223659.1 15612007 889591 1045778..1047811 1 NC_000921.1 similar to H. pylori 26695 gene HP0996; hypothetical protein 1047811 889591 jhp0942 Helicobacter pylori J99 hypothetical protein NP_223659.1 1045778 D 85963 CDS NP_223660.1 15612008 889583 complement(1048376..1048561) 1 NC_000921.1 hypothetical protein 1048561 889583 jhp0943 Helicobacter pylori J99 hypothetical protein NP_223660.1 1048376 R 85963 CDS NP_223661.1 15612009 889585 1049107..1049874 1 NC_000921.1 hypothetical protein 1049874 889585 jhp0944 Helicobacter pylori J99 hypothetical protein NP_223661.1 1049107 D 85963 CDS NP_223662.1 15612010 889586 1049874..1051880 1 NC_000921.1 hypothetical protein 1051880 889586 jhp0945 Helicobacter pylori J99 hypothetical protein NP_223662.1 1049874 D 85963 CDS NP_223663.1 15612011 889587 1051673..1052110 1 NC_000921.1 hypothetical protein 1052110 889587 jhp0946 Helicobacter pylori J99 hypothetical protein NP_223663.1 1051673 D 85963 CDS NP_223664.1 15612012 889588 1052137..1053537 1 NC_000921.1 hypothetical protein 1053537 889588 jhp0947 Helicobacter pylori J99 hypothetical protein NP_223664.1 1052137 D 85963 CDS NP_223665.1 15612013 889603 1053588..1053866 1 NC_000921.1 hypothetical protein 1053866 889603 jhp0948 Helicobacter pylori J99 hypothetical protein NP_223665.1 1053588 D 85963 CDS NP_223666.1 15612014 889596 1053868..1055130 1 NC_000921.1 hypothetical protein 1055130 889596 jhp0949 Helicobacter pylori J99 hypothetical protein NP_223666.1 1053868 D 85963 CDS NP_223667.1 15612015 889590 1055202..1055885 1 NC_000921.1 hypothetical protein 1055885 889590 jhp0950 Helicobacter pylori J99 hypothetical protein NP_223667.1 1055202 D 85963 CDS NP_223668.1 15612016 889592 complement(1055965..1057038) 1 NC_000921.1 integrase/recombinase (XERCD family) 1057038 889592 jhp0951 Helicobacter pylori J99 integrase/recombinase (XERCD family) NP_223668.1 1055965 R 85963 CDS NP_223669.1 15612017 889593 1061075..1061266 1 NC_000921.1 similar to H. pylori 26695 gene HP0427; hypothetical protein 1061266 889593 jhp0952 Helicobacter pylori J99 hypothetical protein NP_223669.1 1061075 D 85963 CDS NP_223670.1 15612018 889594 complement(1061274..1061498) 1 NC_000921.1 hypothetical protein 1061498 889594 jhp0953 Helicobacter pylori J99 hypothetical protein NP_223670.1 1061274 R 85963 CDS NP_223671.1 15612019 889595 1061542..1061982 1 NC_000921.1 hypothetical protein 1061982 889595 jhp0954 Helicobacter pylori J99 hypothetical protein NP_223671.1 1061542 D 85963 CDS NP_223672.1 15612020 889601 1062036..1062689 1 NC_000921.1 hypothetical protein 1062689 889601 jhp0955 Helicobacter pylori J99 hypothetical protein NP_223672.1 1062036 D 85963 CDS NP_223673.1 15612021 889597 1062798..1063283 1 NC_000921.1 hypothetical protein 1063283 889597 jhp0956 Helicobacter pylori J99 hypothetical protein NP_223673.1 1062798 D 85963 CDS NP_223674.1 15612022 889598 1063271..1063873 1 NC_000921.1 hypothetical protein 1063873 889598 jhp0957 Helicobacter pylori J99 hypothetical protein NP_223674.1 1063271 D 85963 CDS NP_223675.1 15612023 889599 1064021..1064176 1 NC_000921.1 hypothetical protein 1064176 889599 jhp0958 Helicobacter pylori J99 hypothetical protein NP_223675.1 1064021 D 85963 CDS NP_223676.1 15612024 889600 1064262..1064918 1 NC_000921.1 hypothetical protein 1064918 889600 jhp0959 Helicobacter pylori J99 hypothetical protein NP_223676.1 1064262 D 85963 CDS NP_223677.1 15612025 889321 1065063..1065281 1 NC_000921.1 hypothetical protein 1065281 889321 jhp0960 Helicobacter pylori J99 hypothetical protein NP_223677.1 1065063 D 85963 CDS NP_223678.1 15612026 889604 1065283..1065468 1 NC_000921.1 hypothetical protein 1065468 889604 jhp0961 Helicobacter pylori J99 hypothetical protein NP_223678.1 1065283 D 85963 CDS NP_223679.1 15612027 889602 complement(1065542..1067389) 1 NC_000921.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 1067389 speA 889602 speA Helicobacter pylori J99 arginine decarboxylase NP_223679.1 1065542 R 85963 CDS NP_223680.1 15612028 889320 complement(1067403..1068572) 1 NC_000921.1 similar to H. pylori 26695 gene HP0421; polysaccharide biosynthesis protein 1068572 889320 jhp0963 Helicobacter pylori J99 polysaccharide biosynthesis protein NP_223680.1 1067403 R 85963 CDS NP_223681.1 15612029 889606 complement(1068577..1069005) 1 NC_000921.1 similar to H. pylori 26695 gene HP0420; hypothetical protein 1069005 889606 jhp0964 Helicobacter pylori J99 hypothetical protein NP_223681.1 1068577 R 85963 CDS NP_223682.1 15612030 889605 complement(1069022..1069807) 1 NC_000921.1 similar to H. pylori 26695 gene HP0419; hypothetical protein 1069807 889605 jhp0965 Helicobacter pylori J99 hypothetical protein NP_223682.1 1069022 R 85963 CDS NP_223683.1 15612031 889615 complement(1069811..1070818) 1 NC_000921.1 similar to H. pylori 26695 gene HP0418; hypothetical protein 1070818 889615 jhp0966 Helicobacter pylori J99 hypothetical protein NP_223683.1 1069811 R 85963 CDS NP_223684.1 15612032 889607 complement(1070819..1072789) 1 NC_000921.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1072789 metG 889607 metG Helicobacter pylori J99 methionyl-tRNA synthetase NP_223684.1 1070819 R 85963 CDS NP_223685.1 15612033 889608 1072958..1074127 1 NC_000921.1 similar to H. pylori 26695 gene HP0416; cyclopocyclopropane fatty acid synthase 1074127 cfa 889608 cfa Helicobacter pylori J99 cyclopocyclopropane fatty acid synthase NP_223685.1 1072958 D 85963 CDS NP_223686.1 15612034 889609 complement(1074137..1076008) 1 NC_000921.1 similar to H. pylori 26695 gene HP0415; hypothetical protein 1076008 889609 jhp0969 Helicobacter pylori J99 hypothetical protein NP_223686.1 1074137 R 85963 CDS NP_223687.1 15612035 889610 complement(1076573..1076671) 1 NC_000921.1 similar to H. pylori 26695 gene HP0412; hypothetical protein 1076671 889610 jhp0970 Helicobacter pylori J99 hypothetical protein NP_223687.1 1076573 R 85963 CDS NP_223688.1 15612036 889611 complement(1077336..1078085) 1 NC_000921.1 similar to H. pylori 26695 gene HP0410; paralog of HpaA 1078085 889611 jhp0971 Helicobacter pylori J99 paralog of HpaA NP_223688.1 1077336 R 85963 CDS NP_223689.1 15612037 889612 complement(1078169..1079695) 1 NC_000921.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1079695 guaA 889612 guaA Helicobacter pylori J99 GMP synthase NP_223689.1 1078169 R 85963 CDS NP_223690.1 15612038 889613 complement(1079692..1080186) 1 NC_000921.1 similar to H. pylori 26695 gene HP0408; hypothetical protein 1080186 889613 jhp0973 Helicobacter pylori J99 hypothetical protein NP_223690.1 1079692 R 85963 CDS NP_223691.1 15612039 889614 complement(1080366..1082756) 1 NC_000921.1 similar to H. pylori 26695 gene HP0407; S/N-oxide reductase 1082756 889614 jhp0974 Helicobacter pylori J99 S/N-oxide reductase NP_223691.1 1080366 R 85963 CDS NP_223692.1 15612040 889617 complement(1082860..1083450) 1 NC_000921.1 similar to H. pylori 26695 gene HP0406; hypothetical protein 1083450 889617 jhp0975 Helicobacter pylori J99 hypothetical protein NP_223692.1 1082860 R 85963 CDS NP_223693.1 15612041 889623 complement(1083476..1084798) 1 NC_000921.1 similar to H. pylori 26695 gene HP0405; nifS-like protein 1084798 889623 jhp0976 Helicobacter pylori J99 nifS-like protein NP_223693.1 1083476 R 85963 CDS NP_223694.1 15612042 889616 complement(1084817..1085131) 1 NC_000921.1 similar to H. pylori 26695 gene HP0404; HIT family protein 1085131 889616 jhp0977 Helicobacter pylori J99 HIT family protein NP_223694.1 1084817 R 85963 CDS NP_223695.1 15612043 889618 1085213..1086199 1 NC_000921.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1086199 pheS 889618 pheS Helicobacter pylori J99 phenylalanyl-tRNA synthetase subunit alpha NP_223695.1 1085213 D 85963 CDS NP_223696.1 15612044 889619 1086199..1088493 1 NC_000921.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1088493 pheT 889619 pheT Helicobacter pylori J99 phenylalanyl-tRNA synthetase subunit beta NP_223696.1 1086199 D 85963 CDS NP_223697.1 15612045 889631 1088513..1089802 1 NC_000921.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1089802 aroA 889631 aroA Helicobacter pylori J99 3-phosphoshikimate 1-carboxyvinyltransferase NP_223697.1 1088513 D 85963 CDS NP_223698.1 15612046 889621 1089792..1090616 1 NC_000921.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1090616 ispH 889621 ispH Helicobacter pylori J99 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NP_223698.1 1089792 D 85963 CDS NP_223699.1 15612047 889620 1090738..1092396 1 NC_000921.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1092396 rpsA 889620 rpsA Helicobacter pylori J99 30S ribosomal protein S1 NP_223699.1 1090738 D 85963 CDS NP_223700.1 15612048 889622 1092425..1092937 1 NC_000921.1 similar to H. pylori 26695 gene HP0398; hypothetical protein 1092937 889622 jhp0983 Helicobacter pylori J99 hypothetical protein NP_223700.1 1092425 D 85963 CDS NP_223701.1 15612049 889632 1092953..1094527 1 NC_000921.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1094527 serA 889632 serA Helicobacter pylori J99 D-3-phosphoglycerate dehydrogenase NP_223701.1 1092953 D 85963 CDS NP_223702.1 15612050 889624 1094537..1096387 1 NC_000921.1 similar to H. pylori 26695 gene HP0396; hypothetical protein 1096387 889624 jhp0985 Helicobacter pylori J99 hypothetical protein NP_223702.1 1094537 D 85963 CDS NP_223703.1 15612051 889625 1096410..1097078 1 NC_000921.1 similar to H. pylori 26695 gene HP0395; hypothetical protein 1097078 889625 jhp0986 Helicobacter pylori J99 hypothetical protein NP_223703.1 1096410 D 85963 CDS NP_223704.1 15612052 889626 1097080..1097838 1 NC_000921.1 similar to H. pylori 26695 gene HP0394; hypothetical protein 1097838 889626 jhp0987 Helicobacter pylori J99 hypothetical protein NP_223704.1 1097080 D 85963 CDS NP_223705.1 15612053 889627 1097840..1098778 1 NC_000921.1 similar to H. pylori 26695 gene HP0393; chemotaxis protein 1098778 cheV_3 889627 cheV_3 Helicobacter pylori J99 chemotaxis protein NP_223705.1 1097840 D 85963 CDS NP_223706.1 15612054 889628 1098835..1101282 1 NC_000921.1 similar to H. pylori 26695 gene HP0392; histidine kinase 1101282 cheA 889628 cheA Helicobacter pylori J99 histidine kinase NP_223706.1 1098835 D 85963 CDS NP_223707.1 15612055 889629 1101279..1101776 1 NC_000921.1 similar to H. pylori 26695 gene HP0391; histidine kinase - MCP coupling protein 1101776 cheW 889629 cheW Helicobacter pylori J99 histidine kinase - MCP coupling protein NP_223707.1 1101279 D 85963 CDS NP_223708.1 15612056 889635 complement(1102036..1102536) 1 NC_000921.1 similar to H. pylori 26695 gene HP0390; thiol peroxidase 1102536 tpx 889635 tpx Helicobacter pylori J99 thiol peroxidase NP_223708.1 1102036 R 85963 CDS NP_223709.1 15612057 889630 1102758..1103399 1 NC_000921.1 similar to H. pylori 26695 gene HP0389; iron-dependent superoxide dismutase 1103399 sodF 889630 sodF Helicobacter pylori J99 iron-dependent superoxide dismutase NP_223709.1 1102758 D 85963 CDS NP_223710.1 15612058 889633 1103453..1104184 1 NC_000921.1 similar to H. pylori 26695 gene HP0388; hypothetical protein 1104184 889633 jhp0993 Helicobacter pylori J99 hypothetical protein NP_223710.1 1103453 D 85963 CDS NP_223711.1 15612059 889634 complement(1104218..1106077) 1 NC_000921.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1106077 priA 889634 priA Helicobacter pylori J99 primosome assembly protein PriA NP_223711.1 1104218 R 85963 CDS NP_223712.1 15612060 889638 complement(1106062..1106298) 1 NC_000921.1 similar to H. pylori 26695 gene HP0386; hypothetical protein 1106298 889638 jhp0995 Helicobacter pylori J99 hypothetical protein NP_223712.1 1106062 R 85963 CDS NP_223713.1 15612061 889276 complement(1106311..1106538) 1 NC_000921.1 similar to H. pylori 26695 gene HP0385; hypothetical protein 1106538 889276 jhp0996 Helicobacter pylori J99 hypothetical protein NP_223713.1 1106311 R 85963 CDS NP_223714.1 15612062 889636 1106739..1107485 1 NC_000921.1 similar to H. pylori 26695 gene HP0384; hypothetical protein 1107485 889636 jhp0997 Helicobacter pylori J99 hypothetical protein NP_223714.1 1106739 D 85963 CDS NP_223715.1 15612063 889637 complement(1107761..1108285) 1 NC_000921.1 similar to H. pylori 26695 gene HP0383; hypothetical protein 1108285 889637 jhp0998 Helicobacter pylori J99 hypothetical protein NP_223715.1 1107761 R 85963 CDS NP_223716.1 15612064 889282 1108465..1109688 1 NC_000921.1 similar to H. pylori 26695 gene HP0382; zinc-metallo protease 1109688 889282 jhp0999 Helicobacter pylori J99 zinc-metallo protease NP_223716.1 1108465 D 85963 CDS NP_223717.1 15612065 889642 1109685..1110515 1 NC_000921.1 similar to H. pylori 26695 gene HP0381; protoporphyrinogen oxidase 1110515 hemG 889642 hemG Helicobacter pylori J99 protoporphyrinogen oxidase NP_223717.1 1109685 D 85963 CDS NP_223718.1 15612066 889639 1110582..1111928 1 NC_000921.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1111928 gdhA 889639 gdhA Helicobacter pylori J99 glutamate dehydrogenase NP_223718.1 1110582 D 85963 CDS NP_223719.1 15612067 889640 complement(join(1111942..1113199,1113199..1113251)) 1 NC_000921.1 similar to TIGR HP0379; expression of this protein is predicted to be regulated by slipped-strand repair at both the (C) and the (A) polynucleotide repeats; length of the (A) polynucleotide repeat has been artificially adjusted (addition of one nucleotide) to give the full length protein; alpha-(1,3)-fucosyltransferase 1113251 fucU 889640 fucU Helicobacter pylori J99 alpha-(1,3)-fucosyltransferase NP_223719.1 1111942 R 85963 CDS NP_223720.1 15612068 889654 complement(1113261..1116071) 1 NC_000921.1 similar to H. pylori 26695 gene HP0378; cytochrome C-type biogenesis protein 1116071 889654 jhp1003 Helicobacter pylori J99 cytochrome C-type biogenesis protein NP_223720.1 1113261 R 85963 CDS NP_223721.1 15612069 889641 complement(1116081..1116752) 1 NC_000921.1 similar to H. pylori 26695 gene HP0377; hypothetical protein 1116752 889641 jhp1004 Helicobacter pylori J99 hypothetical protein NP_223721.1 1116081 R 85963 CDS NP_223722.1 15612070 889645 complement(1116826..1117833) 1 NC_000921.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1117833 hemH 889645 hemH Helicobacter pylori J99 ferrochelatase NP_223722.1 1116826 R 85963 CDS NP_223723.1 15612071 889643 1117889..1118320 1 NC_000921.1 similar to H. pylori 26695 gene HP0375; hypothetical protein 1118320 889643 jhp1006 Helicobacter pylori J99 hypothetical protein NP_223723.1 1117889 D 85963 CDS NP_223724.1 15612072 889644 1118321..1119001 1 NC_000921.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1119001 889644 jhp1007 Helicobacter pylori J99 16S ribosomal RNA methyltransferase RsmE NP_223724.1 1118321 D 85963 CDS NP_223725.1 15612073 889648 complement(1119085..1121340) 1 NC_000921.1 similar to H. pylori 26695 gene HP0373; hypothetical protein 1121340 889648 jhp1008 Helicobacter pylori J99 hypothetical protein NP_223725.1 1119085 R 85963 CDS NP_223726.1 15612074 889646 complement(1121509..1122075) 1 NC_000921.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1122075 dcd 889646 dcd Helicobacter pylori J99 deoxycytidine triphosphate deaminase NP_223726.1 1121509 R 85963 CDS NP_223727.1 15612075 889647 1122205..1122690 1 NC_000921.1 similar to H. pylori 26695 gene HP0371; biotin carboxyl carrier protein 1122690 accB 889647 accB Helicobacter pylori J99 biotin carboxyl carrier protein NP_223727.1 1122205 D 85963 CDS NP_223728.1 15612076 889649 1122696..1124063 1 NC_000921.1 biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1124063 accC 889649 accC Helicobacter pylori J99 biotin carboxylase NP_223728.1 1122696 D 85963 CDS NP_223729.1 15612077 889650 1124156..1125118 1 NC_000921.1 similar to H. pylori 26695 gene HP0369; type II DNA modification enzyme 1125118 889650 jhp1012 Helicobacter pylori J99 type II DNA modification enzyme NP_223729.1 1124156 D 85963 CDS NP_223730.1 15612078 889651 1125118..1125666 1 NC_000921.1 similar to H. pylori 26695 gene HP0368; hypothetical protein 1125666 889651 jhp1013 Helicobacter pylori J99 hypothetical protein NP_223730.1 1125118 D 85963 CDS NP_223731.1 15612079 889652 1125760..1126365 1 NC_000921.1 similar to H. pylori 26695 gene HP0367; hypothetical protein 1126365 889652 jhp1014 Helicobacter pylori J99 hypothetical protein NP_223731.1 1125760 D 85963 CDS NP_223732.1 15612080 889675 1126362..1127498 1 NC_000921.1 similar to H. pylori 26695 gene HP0366; spore coat polysaccharide biosynthesis protein C 1127498 889675 jhp1015 Helicobacter pylori J99 spore coat polysaccharide biosynthesis protein C NP_223732.1 1126362 D 85963 CDS NP_223733.1 15612081 889653 1127804..1128829 1 NC_000921.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1128829 nrdF 889653 nrdF Helicobacter pylori J99 ribonucleotide-diphosphate reductase subunit beta NP_223733.1 1127804 D 85963 CDS NP_223734.1 15612082 889655 1128839..1129468 1 NC_000921.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1129468 pcm 889655 pcm Helicobacter pylori J99 protein-L-isoaspartate O-methyltransferase NP_223734.1 1128839 D 85963 CDS NP_223735.1 15612083 889656 1129490..1130527 1 NC_000921.1 similar to H. pylori 26695 gene HP0362; hypothetical protein 1130527 889656 jhp1018 Helicobacter pylori J99 hypothetical protein NP_223735.1 1129490 D 85963 CDS NP_223736.1 15612084 889659 1130529..1131257 1 NC_000921.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1131257 truA 889659 truA Helicobacter pylori J99 tRNA pseudouridine synthase A NP_223736.1 1130529 D 85963 CDS NP_223737.1 15612085 889657 complement(1131251..1132285) 1 NC_000921.1 similar to H. pylori 26695 gene HP0360; UDP-glucose 4-epimerase 1132285 galE 889657 galE Helicobacter pylori J99 UDP-glucose 4-epimerase NP_223737.1 1131251 R 85963 CDS NP_223739.1 15612087 889658 1133200..1134735 1 NC_000921.1 similar to H. pylori 26695 gene HP0358; hypothetical protein 1134735 889658 jhp1022 Helicobacter pylori J99 hypothetical protein NP_223739.1 1133200 D 85963 CDS NP_223740.1 15612088 889661 1134753..1135505 1 NC_000921.1 similar to H. pylori 26695 gene HP0357; short chain alcohol dehydrogenase 1135505 889661 jhp1023 Helicobacter pylori J99 short chain alcohol dehydrogenase NP_223740.1 1134753 D 85963 CDS NP_223741.1 15612089 889662 complement(1135716..1136588) 1 NC_000921.1 similar to H. pylori 26695 gene HP1098; hypothetical protein 1136588 889662 jhp1024 Helicobacter pylori J99 hypothetical protein NP_223741.1 1135716 R 85963 CDS NP_223742.1 15612090 889663 complement(1136658..1137284) 1 NC_000921.1 similar to H. pylori 26695 gene HP1099; 2-keto-3-deoxy-6-phosphogluconate aldolase 1137284 eda 889663 eda Helicobacter pylori J99 2-keto-3-deoxy-6-phosphogluconate aldolase NP_223742.1 1136658 R 85963 CDS NP_223743.1 15612091 889668 complement(1137303..1139129) 1 NC_000921.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1139129 edd 889668 edd Helicobacter pylori J99 phosphogluconate dehydratase NP_223743.1 1137303 R 85963 CDS NP_223744.1 15612092 889664 1139195..1140472 1 NC_000921.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1140472 zwf 889664 zwf Helicobacter pylori J99 glucose-6-phosphate 1-dehydrogenase NP_223744.1 1139195 D 85963 CDS NP_223745.1 15612093 889665 1140483..1141166 1 NC_000921.1 similar to H. pylori 26695 gene HP1102; dehydrogenase 1141166 889665 jhp1028 Helicobacter pylori J99 dehydrogenase NP_223745.1 1140483 D 85963 CDS NP_223746.1 15612094 889666 1141153..1142163 1 NC_000921.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1142163 glk 889666 glk Helicobacter pylori J99 glucokinase NP_223746.1 1141153 D 85963 CDS NP_223747.1 15612095 889667 1142333..1143385 1 NC_000921.1 similar to H. pylori 26695 gene HP1104; zinc-dependent alcohol dehydrogenase 1143385 889667 jhp1030 Helicobacter pylori J99 zinc-dependent alcohol dehydrogenase NP_223747.1 1142333 D 85963 CDS NP_223748.1 15612096 889679 complement(1143388..1144569) 1 NC_000921.1 similar to H. pylori 26695 gene HP1105; lipopolysaccharide biosynthesis protein 1144569 889679 jhp1031 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223748.1 1143388 R 85963 CDS NP_223749.1 15612097 889669 complement(1144709..1145905) 1 NC_000921.1 lipopolysaccharide biosynthesis protein 1145905 889669 jhp1032 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_223749.1 1144709 R 85963 CDS NP_223750.1 15612098 889670 1146080..1147387 1 NC_000921.1 similar to H. pylori 26695 gene HP1106; hypothetical protein 1147387 889670 jhp1033 Helicobacter pylori J99 hypothetical protein NP_223750.1 1146080 D 85963 CDS NP_223751.1 15612099 889671 complement(1147394..1148056) 1 NC_000921.1 similar to H. pylori 26695 gene HP1107; hypothetical protein 1148056 889671 jhp1034 Helicobacter pylori J99 hypothetical protein NP_223751.1 1147394 R 85963 CDS NP_223752.1 15612100 889672 1148339..1148899 1 NC_000921.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; pyruvate flavodoxin oxidoreductase subunit gamma 1148899 porG 889672 porG Helicobacter pylori J99 pyruvate flavodoxin oxidoreductase subunit gamma NP_223752.1 1148339 D 85963 CDS NP_223753.1 15612101 889673 1148915..1149307 1 NC_000921.1 similar to H. pylori 26695 gene HP1109; pyruvate flavodoxin oxidoreductase subunit delta 1149307 porD 889673 porD Helicobacter pylori J99 pyruvate flavodoxin oxidoreductase subunit delta NP_223753.1 1148915 D 85963 CDS NP_223754.1 15612102 889677 1149317..1150540 1 NC_000921.1 Couples the complete acetyl-CoA oxidation to aromatic ring reduction by the use of the low-potential electron shuttle ferredoxin; pyruvate flavodoxin oxidoreductase subunit alpha 1150540 porA 889677 porA Helicobacter pylori J99 pyruvate flavodoxin oxidoreductase subunit alpha NP_223754.1 1149317 D 85963 CDS NP_223755.1 15612103 889674 1150553..1151497 1 NC_000921.1 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin; ferrodoxin oxidoreductase subunit beta 1151497 porB 889674 porB Helicobacter pylori J99 ferrodoxin oxidoreductase subunit beta NP_223755.1 1150553 D 85963 CDS NP_223756.1 15612104 889681 1151605..1152927 1 NC_000921.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1152927 purB 889681 purB Helicobacter pylori J99 adenylosuccinate lyase NP_223756.1 1151605 D 85963 CDS NP_223757.1 15612105 889676 1153226..1154059 1 NC_000921.1 similar to H. pylori 26695 gene HP1113; hypothetical protein 1154059 889676 jhp1040 Helicobacter pylori J99 hypothetical protein NP_223757.1 1153226 D 85963 CDS NP_223758.1 15612106 889678 complement(1154084..1156060) 1 NC_000921.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1156060 uvrB 889678 uvrB Helicobacter pylori J99 excinuclease ABC subunit B NP_223758.1 1154084 R 85963 CDS NP_223759.1 15612107 889684 complement(1156109..1156912) 1 NC_000921.1 similar to H. pylori 26695 gene HP1115; hypothetical protein 1156912 889684 jhp1042 Helicobacter pylori J99 hypothetical protein NP_223759.1 1156109 R 85963 CDS NP_223760.1 15612108 889682 complement(1156909..1157292) 1 NC_000921.1 hypothetical protein 1157292 889682 jhp1043 Helicobacter pylori J99 hypothetical protein NP_223760.1 1156909 R 85963 CDS NP_223761.1 15612109 889680 complement(1157436..1160900) 1 NC_000921.1 similar to H. pylori 26695 gene HP1116; hypothetical protein 1160900 889680 jhp1044 Helicobacter pylori J99 hypothetical protein NP_223761.1 1157436 R 85963 CDS NP_223762.1 15612110 889296 complement(1161319..1162089) 1 NC_000921.1 similar to H. pylori 26695 gene HP1117; hypothetical protein 1162089 889296 jhp1045 Helicobacter pylori J99 hypothetical protein NP_223762.1 1161319 R 85963 CDS NP_223763.1 15612111 889689 complement(1162333..1164036) 1 NC_000921.1 similar to H. pylori 26695 gene HP1118; gamma-glutamyltranspeptidase 1164036 ggt 889689 ggt Helicobacter pylori J99 gamma-glutamyltranspeptidase NP_223763.1 1162333 R 85963 CDS NP_223764.1 15612112 889683 complement(1164224..1166044) 1 NC_000921.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1166044 flgK 889683 flgK Helicobacter pylori J99 flagellar hook-associated protein FlgK NP_223764.1 1164224 R 85963 CDS NP_223765.1 15612113 889685 complement(1166046..1166480) 1 NC_000921.1 similar to H. pylori 26695 gene HP1120; hypothetical protein 1166480 889685 jhp1048 Helicobacter pylori J99 hypothetical protein NP_223765.1 1166046 R 85963 CDS NP_223766.1 15612114 889686 complement(1166559..1167311) 1 NC_000921.1 hypothetical protein 1167311 889686 jhp1049 Helicobacter pylori J99 hypothetical protein NP_223766.1 1166559 R 85963 CDS NP_223767.1 15612115 889687 complement(1167304..1168269) 1 NC_000921.1 similar to H. pylori 26695 gene HP1121; type II DNA modification (methyltransferase 1168269 889687 jhp1050 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_223767.1 1167304 R 85963 CDS NP_223768.1 15612116 889693 complement(1168412..1168615) 1 NC_000921.1 similar to H. pylori 26695 gene HP1122; hypothetical protein 1168615 889693 jhp1051 Helicobacter pylori J99 hypothetical protein NP_223768.1 1168412 R 85963 CDS NP_223769.1 15612117 889688 complement(1168925..1169482) 1 NC_000921.1 similar to H. pylori 26695 gene HP1123; FKBP-type peptidylprolyl isomerase 1169482 slyD 889688 slyD Helicobacter pylori J99 FKBP-type peptidylprolyl isomerase NP_223769.1 1168925 R 85963 CDS NP_223770.1 15612118 889298 complement(1169469..1170464) 1 NC_000921.1 similar to H. pylori 26695 gene HP1124; hypothetical protein 1170464 889298 jhp1053 Helicobacter pylori J99 hypothetical protein NP_223770.1 1169469 R 85963 CDS NP_223771.1 15612119 889695 complement(1170472..1171011) 1 NC_000921.1 similar to H. pylori 26695 gene HP1125; hypothetical protein 1171011 889695 jhp1054 Helicobacter pylori J99 hypothetical protein NP_223771.1 1170472 R 85963 CDS NP_223772.1 15612120 889692 complement(1171078..1172331) 1 NC_000921.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1172331 tolB 889692 tolB Helicobacter pylori J99 translocation protein TolB NP_223772.1 1171078 R 85963 CDS NP_223773.1 15612121 889690 complement(1172328..1173119) 1 NC_000921.1 similar to H. pylori 26695 gene HP1127 and HP1128; hypothetical protein 1173119 889690 jhp1056 Helicobacter pylori J99 hypothetical protein NP_223773.1 1172328 R 85963 CDS NP_223774.1 15612122 889691 complement(1173138..1173539) 1 NC_000921.1 similar to H. pylori 26695 gene HP1129; biopolymer transport protein 1173539 exbD_1 889691 exbD_1 Helicobacter pylori J99 biopolymer transport protein NP_223774.1 1173138 R 85963 CDS NP_223775.1 15612123 889696 complement(1173591..1174160) 1 NC_000921.1 similar to H. pylori 26695 gene HP1130; biopolymer transport protein 1174160 exbB_1 889696 exbB_1 Helicobacter pylori J99 biopolymer transport protein NP_223775.1 1173591 R 85963 CDS NP_223776.1 15612124 889704 complement(1174171..1174542) 1 NC_000921.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 1174542 atpC 889704 atpC Helicobacter pylori J99 ATP synthase F0F1 subunit epsilon NP_223776.1 1174171 R 85963 CDS NP_223777.1 15612125 889694 complement(1174553..1175962) 1 NC_000921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1175962 atpD 889694 atpD Helicobacter pylori J99 ATP synthase F0F1 subunit beta NP_223777.1 1174553 R 85963 CDS NP_223778.1 15612126 889697 complement(1175987..1176892) 1 NC_000921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1176892 atpG 889697 atpG Helicobacter pylori J99 ATP synthase F0F1 subunit gamma NP_223778.1 1175987 R 85963 CDS NP_223779.1 15612127 889698 complement(1176907..1178418) 1 NC_000921.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1178418 atpA 889698 atpA Helicobacter pylori J99 ATP synthase F0F1 subunit alpha NP_223779.1 1176907 R 85963 CDS NP_223780.1 15612128 889699 complement(1178441..1178983) 1 NC_000921.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 1178983 atpH 889699 atpH Helicobacter pylori J99 ATP synthase F0F1 subunit delta NP_223780.1 1178441 R 85963 CDS NP_223781.1 15612129 889700 complement(1178984..1179499) 1 NC_000921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 1179499 atpF 889700 atpF Helicobacter pylori J99 ATP synthase F0F1 subunit B NP_223781.1 1178984 R 85963 CDS NP_223782.1 15612130 889701 complement(1179503..1179937) 1 NC_000921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; ATP synthase F0F1 subunit B' 1179937 atpX 889701 atpX Helicobacter pylori J99 ATP synthase F0F1 subunit B' NP_223782.1 1179503 R 85963 CDS NP_223783.1 15612131 889702 complement(1180042..1180914) 1 NC_000921.1 similar to H. pylori 26695 gene HP1138; plasmid replication-partition related protein 1180914 889702 jhp1066 Helicobacter pylori J99 plasmid replication-partition related protein NP_223783.1 1180042 R 85963 CDS NP_223784.1 15612132 889720 complement(1180917..1181711) 1 NC_000921.1 similar to H. pylori 26695 gene HP1139; hypothetical protein 1181711 889720 jhp1067 Helicobacter pylori J99 hypothetical protein NP_223784.1 1180917 R 85963 CDS NP_223785.1 15612133 889703 complement(1181714..1182352) 1 NC_000921.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1182352 889703 jhp1068 Helicobacter pylori J99 biotin--protein ligase NP_223785.1 1181714 R 85963 CDS NP_223786.1 15612134 889705 complement(1182349..1183266) 1 NC_000921.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1183266 fmt 889705 fmt Helicobacter pylori J99 methionyl-tRNA formyltransferase NP_223786.1 1182349 R 85963 CDS NP_223787.1 15612135 889706 complement(1183290..1185569) 1 NC_000921.1 similar to H. pylori 26695 gene HP1142; hypothetical protein 1185569 889706 jhp1070 Helicobacter pylori J99 hypothetical protein NP_223787.1 1183290 R 85963 CDS NP_223788.1 15612136 889707 complement(1185604..1186905) 1 NC_000921.1 similar to H. pylori 26695 gene HP1143; hypothetical protein 1186905 889707 jhp1071 Helicobacter pylori J99 hypothetical protein NP_223788.1 1185604 R 85963 CDS NP_223789.1 15612137 889708 1187115..1187408 1 NC_000921.1 similar to H. pylori 26695 gene HP1144; hypothetical protein 1187408 889708 jhp1072 Helicobacter pylori J99 hypothetical protein NP_223789.1 1187115 D 85963 CDS NP_223790.1 15612138 889709 complement(1190266..1191123) 1 NC_000921.1 similar to H. pylori 26695 gene HP1145 and HP1146; hypothetical protein 1191123 889709 jhp1073 Helicobacter pylori J99 hypothetical protein NP_223790.1 1190266 R 85963 CDS NP_223791.1 15612139 889710 complement(1191976..1192332) 1 NC_000921.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1192332 rplS 889710 rplS Helicobacter pylori J99 50S ribosomal protein L19 NP_223791.1 1191976 R 85963 CDS NP_223792.1 15612140 889711 complement(1192354..1193043) 1 NC_000921.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1193043 trmD 889711 trmD Helicobacter pylori J99 tRNA (guanine-N(1)-)-methyltransferase NP_223792.1 1192354 R 85963 CDS NP_223793.1 15612141 889712 complement(1193044..1193589) 1 NC_000921.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1193589 rimM 889712 rimM Helicobacter pylori J99 16S rRNA-processing protein RimM NP_223793.1 1193044 R 85963 CDS NP_223794.1 15612142 889713 complement(1193599..1193952) 1 NC_000921.1 similar to H. pylori 26695 gene HP1150; hypothetical protein 1193952 889713 jhp1077 Helicobacter pylori J99 hypothetical protein NP_223794.1 1193599 R 85963 CDS NP_223795.1 15612143 889714 complement(1193969..1194199) 1 NC_000921.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1194199 rpsP 889714 rpsP Helicobacter pylori J99 30S ribosomal protein S16 NP_223795.1 1193969 R 85963 CDS NP_223796.1 15612144 889717 complement(1194273..1195619) 1 NC_000921.1 similar to H. pylori 26695 gene HP1152; signal recognition particle protein 1195619 ffh 889717 ffh Helicobacter pylori J99 signal recognition particle protein NP_223796.1 1194273 R 85963 CDS NP_223797.1 15612145 889715 complement(1195634..1198252) 1 NC_000921.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1198252 valS 889715 valS Helicobacter pylori J99 valyl-tRNA synthetase NP_223797.1 1195634 R 85963 CDS NP_223798.1 15612146 889716 1198390..1198797 1 NC_000921.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1198797 889716 jhp1081 Helicobacter pylori J99 flagellar assembly protein FliW NP_223798.1 1198390 D 85963 CDS NP_223799.1 15612147 889722 1198809..1199870 1 NC_000921.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1199870 murG 889722 murG Helicobacter pylori J99 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_223799.1 1198809 D 85963 CDS NP_223800.1 15612148 889719 1199979..1202072 1 NC_000921.1 similar to H. pylori 26695 gene HP1156; hypothetical protein 1202072 889719 jhp1083 Helicobacter pylori J99 hypothetical protein NP_223800.1 1199979 D 85963 CDS NP_223801.1 15612149 889718 1202095..1205808 1 NC_000921.1 similar to H. pylori 26695 gene HP1157; hypothetical protein 1205808 889718 jhp1084 Helicobacter pylori J99 hypothetical protein NP_223801.1 1202095 D 85963 CDS NP_223802.1 15612150 889724 1205822..1206595 1 NC_000921.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1206595 proC 889724 proC Helicobacter pylori J99 pyrroline-5-carboxylate reductase NP_223802.1 1205822 D 85963 CDS NP_223803.1 15612151 889721 1206622..1207149 1 NC_000921.1 similar to H. pylori 26695 gene HP1159; cAMP-induced cell filamentation protein 1207149 fic 889721 fic Helicobacter pylori J99 cAMP-induced cell filamentation protein NP_223803.1 1206622 D 85963 CDS NP_223804.1 15612152 889729 complement(1207235..1207660) 1 NC_000921.1 similar to H. pylori 26695 gene HP1160; metalloprotease 1207660 889729 jhp1087 Helicobacter pylori J99 metalloprotease NP_223804.1 1207235 R 85963 CDS NP_223805.1 15612153 889723 complement(1207715..1208209) 1 NC_000921.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 1208209 fldA 889723 fldA Helicobacter pylori J99 flavodoxin FldA NP_223805.1 1207715 R 85963 CDS NP_223806.1 15612154 889731 complement(1208301..1208882) 1 NC_000921.1 similar to H. pylori 26695 gene HP1162; hypothetical protein 1208882 889731 jhp1089 Helicobacter pylori J99 hypothetical protein NP_223806.1 1208301 R 85963 CDS NP_223807.1 15612155 889725 1209007..1209198 1 NC_000921.1 similar to H. pylori 26695 gene HP1163; component of cation transport for cbb3-type oxidase 1209198 fixS 889725 fixS Helicobacter pylori J99 component of cation transport for cbb3-type oxidase NP_223807.1 1209007 D 85963 CDS NP_223808.1 15612156 889728 1209224..1210198 1 NC_000921.1 similar to H. pylori 26695 gene HP1164; thioredoxin reductase 1210198 trxB_2 889728 trxB_2 Helicobacter pylori J99 thioredoxin reductase NP_223808.1 1209224 D 85963 CDS NP_223809.1 15612157 889726 complement(1210206..1211366) 1 NC_000921.1 similar to H. pylori 26695 gene HP1165; hypothetical protein 1211366 889726 jhp1092 Helicobacter pylori J99 hypothetical protein NP_223809.1 1210206 R 85963 CDS NP_223810.1 15612158 889727 1211430..1213067 1 NC_000921.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1213067 pgi 889727 pgi Helicobacter pylori J99 glucose-6-phosphate isomerase NP_223810.1 1211430 D 85963 CDS NP_223811.1 15612159 889743 1213371..1214786 1 NC_000921.1 similar to H. pylori 26695 gene HP1167; hypothetical protein 1214786 889743 jhp1094 Helicobacter pylori J99 hypothetical protein NP_223811.1 1213371 D 85963 CDS NP_223812.1 15612160 889737 complement(1215246..1217309) 1 NC_000921.1 similar to H. pylori 26695 gene HP1168; hypothetical protein 1217309 889737 jhp1095 Helicobacter pylori J99 hypothetical protein NP_223812.1 1215246 R 85963 CDS NP_223813.1 15612161 889730 1217517..1218170 1 NC_000921.1 similar to H. pylori 26695 gene HP1169; amino acid ABC transporter permease 1218170 889730 jhp1096 Helicobacter pylori J99 amino acid ABC transporter permease NP_223813.1 1217517 D 85963 CDS NP_223814.1 15612162 889732 1218172..1218843 1 NC_000921.1 similar to H. pylori 26695 gene HP1170; amino acid ABC transporter permease 1218843 889732 jhp1097 Helicobacter pylori J99 amino acid ABC transporter permease NP_223814.1 1218172 D 85963 CDS NP_223815.1 15612163 889733 1218845..1219591 1 NC_000921.1 similar to H. pylori 26695 gene HP1171; amino acid ABC transporter ATP-binding protein 1219591 889733 jhp1098 Helicobacter pylori J99 amino acid ABC transporter ATP-binding protein NP_223815.1 1218845 D 85963 CDS NP_223816.1 15612164 889734 1219640..1220473 1 NC_000921.1 similar to H. pylori 26695 gene HP1172; amino acid ABC transporter 1220473 889734 jhp1099 Helicobacter pylori J99 amino acid ABC transporter NP_223816.1 1219640 D 85963 CDS NP_223817.1 15612165 889735 1220595..1221152 1 NC_000921.1 similar to H. pylori 26695 gene HP1173; hypothetical protein 1221152 889735 jhp1100 Helicobacter pylori J99 hypothetical protein NP_223817.1 1220595 D 85963 CDS NP_223818.1 15612166 889736 complement(1221423..1222646) 1 NC_000921.1 similar to H. pylori 26695 gene HP1174; glucose/galactose transporter 1222646 gluP 889736 gluP Helicobacter pylori J99 glucose/galactose transporter NP_223818.1 1221423 R 85963 CDS NP_223819.1 15612167 889738 complement(1222775..1224082) 1 NC_000921.1 similar to H. pylori 26695 gene HP1175; hypothetical protein 1224082 889738 jhp1102 Helicobacter pylori J99 hypothetical protein NP_223819.1 1222775 R 85963 CDS NP_223820.1 15612168 889739 complement(1224524..1226455) 1 NC_000921.1 similar to H. pylori 26695 gene HP1177; Outer membrane function 1226455 889739 jhp1103 Helicobacter pylori J99 Outer membrane function NP_223820.1 1224524 R 85963 CDS NP_223821.1 15612169 889740 complement(1226918..1227619) 1 NC_000921.1 similar to H. pylori 26695 gene HP1178; purine nucleoside phosphorylase 1227619 deoD 889740 deoD Helicobacter pylori J99 purine nucleoside phosphorylase NP_223821.1 1226918 R 85963 CDS NP_223822.1 15612170 889741 complement(1227616..1228857) 1 NC_000921.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1228857 deoB 889741 deoB Helicobacter pylori J99 phosphopentomutase NP_223822.1 1227616 R 85963 CDS NP_223823.1 15612171 889751 complement(1228869..1230125) 1 NC_000921.1 similar to H. pylori 26695 gene HP1180; nucleoside transporter 1230125 889751 jhp1106 Helicobacter pylori J99 nucleoside transporter NP_223823.1 1228869 R 85963 CDS NP_223824.1 15612172 889742 1230455..1231786 1 NC_000921.1 similar to H. pylori 26695 gene HP1181; multidrug ABC transporter 1231786 889742 jhp1107 Helicobacter pylori J99 multidrug ABC transporter NP_223824.1 1230455 D 85963 CDS NP_223825.1 15612173 889750 1231802..1232563 1 NC_000921.1 similar to H. pylori 26695 gene HP1182; hypothetical protein 1232563 889750 jhp1108 Helicobacter pylori J99 hypothetical protein NP_223825.1 1231802 D 85963 CDS NP_223826.1 15612174 889744 complement(1232568..1233719) 1 NC_000921.1 similar to H. pylori 26695 gene HP1183; Na+/H+ antiporter 1233719 889744 jhp1109 Helicobacter pylori J99 Na+/H+ antiporter NP_223826.1 1232568 R 85963 CDS NP_223827.1 15612175 889745 complement(1233745..1235124) 1 NC_000921.1 similar to H. pylori 26695 gene HP1184; hypothetical protein 1235124 889745 jhp1110 Helicobacter pylori J99 hypothetical protein NP_223827.1 1233745 R 85963 CDS NP_223828.1 15612176 889746 complement(1235294..1236469) 1 NC_000921.1 similar to H. pylori 26695 gene HP1185; sugar efflux transporter 1236469 889746 jhp1111 Helicobacter pylori J99 sugar efflux transporter NP_223828.1 1235294 R 85963 CDS NP_223829.1 15612177 889747 1236741..1237484 1 NC_000921.1 similar to H. pylori 26695 gene HP1186; carbonic anhydrase 1237484 889747 jhp1112 Helicobacter pylori J99 carbonic anhydrase NP_223829.1 1236741 D 85963 CDS NP_223830.1 15612178 889748 complement(1237715..1238866) 1 NC_000921.1 similar to H. pylori 26695 gene HP1187; hypothetical protein 1238866 889748 jhp1113 Helicobacter pylori J99 hypothetical protein NP_223830.1 1237715 R 85963 CDS NP_223831.1 15612179 889756 complement(1239301..1240341) 1 NC_000921.1 similar to H. pylori 26695 gene HP1189; aspartate-semialdehyde dehydrogenase 1240341 asd 889756 asd Helicobacter pylori J99 aspartate-semialdehyde dehydrogenase NP_223831.1 1239301 R 85963 CDS NP_223832.1 15612180 889749 complement(1240328..1241656) 1 NC_000921.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1241656 hisS 889749 hisS Helicobacter pylori J99 histidyl-tRNA synthetase NP_223832.1 1240328 R 85963 CDS NP_223833.1 15612181 889772 1241718..1242767 1 NC_000921.1 similar to H. pylori 26695 gene HP1191; ADP-heptose--LPS heptosyltransferase II 1242767 waaF 889772 waaF Helicobacter pylori J99 ADP-heptose--LPS heptosyltransferase II NP_223833.1 1241718 D 85963 CDS NP_223834.1 15612182 889752 complement(1242951..1243115) 1 NC_000921.1 similar to H. pylori 26695 gene HP1192; motility protein 1243115 889752 jhp1117 Helicobacter pylori J99 motility protein NP_223834.1 1242951 R 85963 CDS NP_223835.1 15612183 889753 complement(1243658..1245736) 1 NC_000921.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1245736 fusA 889753 fusA Helicobacter pylori J99 elongation factor G NP_223835.1 1243658 R 85963 CDS NP_223836.1 15612184 889754 complement(1245748..1246215) 1 NC_000921.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1246215 rpsG 889754 rpsG Helicobacter pylori J99 30S ribosomal protein S7 NP_223836.1 1245748 R 85963 CDS NP_223837.1 15612185 889755 complement(1246231..1246638) 1 NC_000921.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1246638 rpsL 889755 rpsL Helicobacter pylori J99 30S ribosomal protein S12 NP_223837.1 1246231 R 85963 CDS NP_223838.1 15612186 889766 complement(1246726..1255398) 1 NC_000921.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' 1255398 rpoB 889766 rpoB Helicobacter pylori J99 DNA-directed RNA polymerase subunit beta/beta' NP_223838.1 1246726 R 85963 CDS NP_223839.1 15612187 889757 complement(1255620..1255997) 1 NC_000921.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1255997 rplL 889757 rplL Helicobacter pylori J99 50S ribosomal protein L7/L12 NP_223839.1 1255620 R 85963 CDS NP_223840.1 15612188 889758 complement(1256040..1256534) 1 NC_000921.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1256534 rplJ 889758 rplJ Helicobacter pylori J99 50S ribosomal protein L10 NP_223840.1 1256040 R 85963 CDS NP_223841.1 15612189 889759 complement(1256643..1257347) 1 NC_000921.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1257347 rplA 889759 rplA Helicobacter pylori J99 50S ribosomal protein L1 NP_223841.1 1256643 R 85963 CDS NP_223842.1 15612190 889760 complement(1257392..1257817) 1 NC_000921.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1257817 rplK 889760 rplK Helicobacter pylori J99 50S ribosomal protein L11 NP_223842.1 1257392 R 85963 CDS NP_223843.1 15612191 889761 complement(1257835..1258365) 1 NC_000921.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1258365 nusG 889761 nusG Helicobacter pylori J99 transcription antitermination protein NusG NP_223843.1 1257835 R 85963 CDS NP_223844.1 15612562 889336 complement(1258392..1258571) 1 NC_000921.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1258571 secE 889336 secE Helicobacter pylori J99 preprotein translocase subunit SecE NP_223844.1 1258392 R 85963 CDS NP_223845.1 15612192 889762 complement(1258818..1258976) 1 NC_000921.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1258976 rpmG 889762 rpmG Helicobacter pylori J99 50S ribosomal protein L33 NP_223845.1 1258818 R 85963 CDS NP_223846.1 15612193 889765 complement(1259023..1260222) 1 NC_000921.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1260222 tuf 889765 tuf Helicobacter pylori J99 elongation factor Tu NP_223846.1 1259023 R 85963 CDS NP_223847.1 15612194 889763 1260926..1262662 1 NC_000921.1 similar to H. pylori 26695 gene HP1206; ABC transporter ATP-binding protein 1262662 889763 jhp1129 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_223847.1 1260926 D 85963 CDS NP_223848.1 15612195 889764 complement(1262671..1263339) 1 NC_000921.1 similar to H. pylori 26695 gene HP1207; hypothetical protein 1263339 889764 jhp1130 Helicobacter pylori J99 hypothetical protein NP_223848.1 1262671 R 85963 CDS NP_223849.1 15612196 889767 complement(1263527..1264516) 1 NC_000921.1 similar to H. pylori 26695 gene HP1208; type II DNA modification (methyltransferase 1264516 M.HpyI 889767 M.HpyI Helicobacter pylori J99 type II DNA modification (methyltransferase NP_223849.1 1263527 R 85963 CDS NP_223850.1 15612197 889769 complement(1264845..1265024) 1 NC_000921.1 hypothetical protein 1265024 889769 jhp1132 Helicobacter pylori J99 hypothetical protein NP_223850.1 1264845 R 85963 CDS NP_223851.1 15612198 889768 complement(1265253..1265768) 1 NC_000921.1 similar to H. pylori 26695 gene HP1210; O-serine acetyltransferase 1265768 cysE 889768 cysE Helicobacter pylori J99 O-serine acetyltransferase NP_223851.1 1265253 R 85963 CDS NP_223853.1 15612200 889771 complement(1266365..1266682) 1 NC_000921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 1266682 atpE 889771 atpE Helicobacter pylori J99 ATP synthase F0F1 subunit C NP_223853.1 1266365 R 85963 CDS NP_223854.1 15612201 889775 complement(1266815..1268881) 1 NC_000921.1 similar to H. pylori 26695 gene HP1213; polynucleotide phosphorylase 1268881 pnp 889775 pnp Helicobacter pylori J99 polynucleotide phosphorylase NP_223854.1 1266815 R 85963 CDS NP_223855.1 15612202 889780 complement(1268884..1269588) 1 NC_000921.1 similar to H. pylori 26695 gene HP1214; hypothetical protein 1269588 889780 jhp1137 Helicobacter pylori J99 hypothetical protein NP_223855.1 1268884 R 85963 CDS NP_223856.1 15612203 889773 complement(1269602..1271902) 1 NC_000921.1 similar to H. pylori 26695 gene HP1215 and HP1216; role in outermembrane permeability 1271902 imp 889773 imp Helicobacter pylori J99 role in outermembrane permeability NP_223856.1 1269602 R 85963 CDS NP_223857.1 15612204 889779 complement(1271865..1272344) 1 NC_000921.1 similar to H. pylori 26695 gene HP1217; hypothetical protein 1272344 889779 jhp1139 Helicobacter pylori J99 hypothetical protein NP_223857.1 1271865 R 85963 CDS NP_223858.1 15612205 889774 complement(1272393..1273667) 1 NC_000921.1 similar to H. pylori 26695 gene HP1218; glycinamide ribonucleotide synthetase 1273667 purD 889774 purD Helicobacter pylori J99 glycinamide ribonucleotide synthetase NP_223858.1 1272393 R 85963 CDS NP_223859.1 15612206 889776 complement(1273981..1274667) 1 NC_000921.1 similar to H. pylori 26695 gene HP1220; ABC transporter ATP-binding protein 1274667 889776 jhp1141 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_223859.1 1273981 R 85963 CDS NP_223860.1 15612207 889777 complement(1274661..1275365) 1 NC_000921.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1275365 889777 jhp1142 Helicobacter pylori J99 undecaprenyl pyrophosphate synthase NP_223860.1 1274661 R 85963 CDS NP_223861.1 15612208 889778 complement(1275405..1278245) 1 NC_000921.1 similar to H. pylori 26695 gene HP1222; D-lactate dehydrogenase 1278245 dld 889778 dld Helicobacter pylori J99 D-lactate dehydrogenase NP_223861.1 1275405 R 85963 CDS NP_223862.1 15612209 889784 1278317..1278655 1 NC_000921.1 similar to H. pylori 26695 gene HP1223; hypothetical protein 1278655 889784 jhp1144 Helicobacter pylori J99 hypothetical protein NP_223862.1 1278317 D 85963 CDS NP_223863.1 15612210 889792 1278658..1279329 1 NC_000921.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1279329 hemD 889792 hemD Helicobacter pylori J99 uroporphyrinogen-III synthase NP_223863.1 1278658 D 85963 CDS NP_223864.1 15612211 889781 1279386..1279778 1 NC_000921.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1279778 889781 jhp1146 Helicobacter pylori J99 camphor resistance protein CrcB NP_223864.1 1279386 D 85963 CDS NP_223865.1 15612212 889782 complement(1279829..1280866) 1 NC_000921.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1280866 hemN_2 889782 hemN_2 Helicobacter pylori J99 coproporphyrinogen III oxidase NP_223865.1 1279829 R 85963 CDS NP_223866.1 15612213 889783 1280962..1281252 1 NC_000921.1 similar to H. pylori 26695 gene HP1227; periplasmic cytochrome C-553 1281252 889783 jhp1148 Helicobacter pylori J99 periplasmic cytochrome C-553 NP_223866.1 1280962 D 85963 CDS NP_223867.1 15612214 889787 1281413..1281886 1 NC_000921.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1281886 mutT 889787 mutT Helicobacter pylori J99 dinucleoside polyphosphate hydrolase NP_223867.1 1281413 D 85963 CDS NP_223868.1 15612215 889810 1281880..1283097 1 NC_000921.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1283097 lysC 889810 lysC Helicobacter pylori J99 aspartate kinase NP_223868.1 1281880 D 85963 CDS NP_223869.1 15612216 889785 1283094..1283636 1 NC_000921.1 similar to H. pylori 26695 gene HP1230; hypothetical protein 1283636 889785 jhp1151 Helicobacter pylori J99 hypothetical protein NP_223869.1 1283094 D 85963 CDS NP_223870.1 15612217 889786 1283633..1284289 1 NC_000921.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1284289 holB 889786 holB Helicobacter pylori J99 DNA polymerase III subunit delta' NP_223870.1 1283633 D 85963 CDS NP_223871.1 15612218 889788 1284286..1285428 1 NC_000921.1 similar to H. pylori 26695 gene HP1232; dihydropteroate synthase 1285428 folP 889788 folP Helicobacter pylori J99 dihydropteroate synthase NP_223871.1 1284286 D 85963 CDS NP_223872.1 15612219 889789 complement(1285523..1285984) 1 NC_000921.1 similar to H. pylori 26695 gene HP1233; hypothetical protein 1285984 889789 jhp1154 Helicobacter pylori J99 hypothetical protein NP_223872.1 1285523 R 85963 CDS NP_223873.1 15612220 889790 1286335..1287231 1 NC_000921.1 similar to H. pylori 26695 gene HP1234; hypothetical protein 1287231 889790 jhp1155 Helicobacter pylori J99 hypothetical protein NP_223873.1 1286335 D 85963 CDS NP_223874.1 15612221 889804 1287235..1288482 1 NC_000921.1 similar to H. pylori 26695 gene HP1235; hypothetical protein 1288482 889804 jhp1156 Helicobacter pylori J99 hypothetical protein NP_223874.1 1287235 D 85963 CDS NP_223875.1 15612222 889791 1288561..1289112 1 NC_000921.1 similar to H. pylori 26695 gene HP1236; hypothetical protein 1289112 889791 jhp1157 Helicobacter pylori J99 hypothetical protein NP_223875.1 1288561 D 85963 CDS NP_223876.1 15612223 889793 1289112..1290239 1 NC_000921.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1290239 carA 889793 carA Helicobacter pylori J99 carbamoyl phosphate synthase small subunit NP_223876.1 1289112 D 85963 CDS NP_223877.1 15612224 889794 1290408..1291412 1 NC_000921.1 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1291412 amiF 889794 amiF Helicobacter pylori J99 formamidase NP_223877.1 1290408 D 85963 CDS NP_223878.1 15612225 889795 complement(1291895..1292305) 1 NC_000921.1 hypothetical protein 1292305 889795 jhp1160 Helicobacter pylori J99 hypothetical protein NP_223878.1 1291895 R 85963 CDS NP_223879.1 15612226 889796 complement(1292482..1293054) 1 NC_000921.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1293054 maf 889796 maf Helicobacter pylori J99 Maf-like protein NP_223879.1 1292482 R 85963 CDS NP_223880.1 15612227 889797 complement(1293056..1295599) 1 NC_000921.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1295599 alaS 889797 alaS Helicobacter pylori J99 alanyl-tRNA synthetase NP_223880.1 1293056 R 85963 CDS NP_223881.1 15612228 889798 1295719..1295949 1 NC_000921.1 similar to H. pylori 26695 gene HP1242; hypothetical protein 1295949 889798 jhp1163 Helicobacter pylori J99 hypothetical protein NP_223881.1 1295719 D 85963 CDS NP_223882.1 15612229 889799 complement(1296915..1299026) 1 NC_000921.1 similar to H. pylori 26695 gene HP0896; hypothetical protein 1299026 babB 889799 babB Helicobacter pylori J99 hypothetical protein NP_223882.1 1296915 R 85963 CDS NP_223883.1 15612230 889800 complement(1299303..1299560) 1 NC_000921.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1299560 rpsR 889800 rpsR Helicobacter pylori J99 30S ribosomal protein S18 NP_223883.1 1299303 R 85963 CDS NP_223884.1 15612231 889812 complement(1299583..1300128) 1 NC_000921.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1300128 ssb 889812 ssb Helicobacter pylori J99 single-stranded DNA-binding protein NP_223884.1 1299583 R 85963 CDS NP_223885.1 15612232 889801 complement(1300143..1300571) 1 NC_000921.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1300571 rpsF 889801 rpsF Helicobacter pylori J99 30S ribosomal protein S6 NP_223885.1 1300143 R 85963 CDS NP_223886.1 15612233 889802 complement(1300700..1301722) 1 NC_000921.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1301722 889802 jhp1168 Helicobacter pylori J99 DNA polymerase III subunit delta NP_223886.1 1300700 R 85963 CDS NP_223887.1 15612234 889803 complement(1301712..1303646) 1 NC_000921.1 similar to H. pylori 26695 gene HP1248; ribonuclease II family protein 1303646 vacB 889803 vacB Helicobacter pylori J99 ribonuclease II family protein NP_223887.1 1301712 R 85963 CDS NP_223888.1 15612235 889805 complement(1303646..1304446) 1 NC_000921.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1304446 aroE 889805 aroE Helicobacter pylori J99 shikimate 5-dehydrogenase NP_223888.1 1303646 R 85963 CDS NP_223889.1 15612236 889807 complement(1304454..1305113) 1 NC_000921.1 similar to H. pylori 26695 gene HP1250; hypothetical protein 1305113 889807 jhp1171 Helicobacter pylori J99 hypothetical protein NP_223889.1 1304454 R 85963 CDS NP_223890.1 15612237 889817 complement(1305122..1306168) 1 NC_000921.1 similar to H. pylori 26695 gene HP1251; peptide ABC transporter ATP-binding protein 1306168 889817 jhp1172 Helicobacter pylori J99 peptide ABC transporter ATP-binding protein NP_223890.1 1305122 R 85963 CDS NP_223891.1 15612238 889806 complement(1306165..1307952) 1 NC_000921.1 similar to H. pylori 26695 gene HP1252; hypothetical protein 1307952 889806 jhp1173 Helicobacter pylori J99 hypothetical protein NP_223891.1 1306165 R 85963 CDS NP_223892.1 15612239 889808 complement(1307953..1308933) 1 NC_000921.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1308933 trpS 889808 trpS Helicobacter pylori J99 tryptophanyl-tRNA synthetase NP_223892.1 1307953 R 85963 CDS NP_223893.1 15612240 889809 complement(1309005..1309742) 1 NC_000921.1 similar to H. pylori 26695 gene HP1254; hypothetical protein 1309742 889809 jhp1175 Helicobacter pylori J99 hypothetical protein NP_223893.1 1309005 R 85963 CDS NP_223894.1 15612241 889820 1309875..1310471 1 NC_000921.1 similar to H. pylori 26695 gene HP1255; preprotein translocase subunit SecG 1310471 secG 889820 secG Helicobacter pylori J99 preprotein translocase subunit SecG NP_223894.1 1309875 D 85963 CDS NP_223895.1 15612242 890458 1310471..1311028 1 NC_000921.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1311028 frr 890458 frr Helicobacter pylori J99 ribosome recycling factor NP_223895.1 1310471 D 85963 CDS NP_223896.1 15612243 889811 1311032..1311637 1 NC_000921.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1311637 pyrE 889811 pyrE Helicobacter pylori J99 orotate phosphoribosyltransferase NP_223896.1 1311032 D 85963 CDS NP_223897.1 15612244 889813 1311627..1312085 1 NC_000921.1 similar to H. pylori 26695 gene HP1258; hypothetical protein 1312085 889813 jhp1179 Helicobacter pylori J99 hypothetical protein NP_223897.1 1311627 D 85963 CDS NP_223898.1 15612245 889814 1312082..1312786 1 NC_000921.1 similar to H. pylori 26695 gene HP1259; hypothetical protein 1312786 889814 jhp1180 Helicobacter pylori J99 hypothetical protein NP_223898.1 1312082 D 85963 CDS NP_223899.1 15612246 889815 1312879..1313280 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1313280 nuoA 889815 nuoA Helicobacter pylori J99 NADH dehydrogenase subunit A NP_223899.1 1312879 D 85963 CDS NP_223900.1 15612247 889823 1313280..1313759 1 NC_000921.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1313759 nuoB 889823 nuoB Helicobacter pylori J99 NADH dehydrogenase subunit B NP_223900.1 1313280 D 85963 CDS NP_223901.1 15612248 890452 1313759..1314556 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1314556 nuoC 890452 nuoC Helicobacter pylori J99 NADH dehydrogenase subunit C NP_223901.1 1313759 D 85963 CDS NP_223902.1 15612249 889816 1314558..1315787 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1315787 nuoD 889816 nuoD Helicobacter pylori J99 NADH dehydrogenase subunit D NP_223902.1 1314558 D 85963 CDS NP_223903.1 15612250 889818 1315784..1316014 1 NC_000921.1 similar to H. pylori 26695 gene HP1264; NADH oxidoreductase I 1316014 nuoE 889818 nuoE Helicobacter pylori J99 NADH oxidoreductase I NP_223903.1 1315784 D 85963 CDS NP_223904.1 15612251 890462 1316017..1317003 1 NC_000921.1 similar to H. pylori 26695 gene HP1265; NADH oxidoreductase I 1317003 nuoF 890462 nuoF Helicobacter pylori J99 NADH oxidoreductase I NP_223904.1 1316017 D 85963 CDS NP_223905.1 15612252 889822 1317000..1319549 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1319549 nuoG 889822 nuoG Helicobacter pylori J99 NADH dehydrogenase subunit G NP_223905.1 1317000 D 85963 CDS NP_223906.1 15612253 890456 1319546..1320535 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1320535 nuoH 890456 nuoH Helicobacter pylori J99 NADH dehydrogenase subunit H NP_223906.1 1319546 D 85963 CDS NP_223907.1 15612254 889819 1320545..1321207 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1321207 nuoI 889819 nuoI Helicobacter pylori J99 NADH dehydrogenase subunit I NP_223907.1 1320545 D 85963 CDS NP_223908.1 15612255 890460 1321200..1321748 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1321748 nuoJ 890460 nuoJ Helicobacter pylori J99 NADH dehydrogenase subunit J NP_223908.1 1321200 D 85963 CDS NP_223909.1 15612256 889821 1321745..1322047 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1322047 nuoK 889821 nuoK Helicobacter pylori J99 NADH dehydrogenase subunit K NP_223909.1 1321745 D 85963 CDS NP_223910.1 15612257 890459 1322050..1323888 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1323888 nuoL 890459 nuoL Helicobacter pylori J99 NADH dehydrogenase subunit L NP_223910.1 1322050 D 85963 CDS NP_223911.1 15612258 889824 1323892..1325430 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1325430 nuoM 889824 nuoM Helicobacter pylori J99 NADH dehydrogenase subunit M NP_223911.1 1323892 D 85963 CDS NP_223912.1 15612259 890455 1325417..1326895 1 NC_000921.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1326895 nuoN 890455 nuoN Helicobacter pylori J99 NADH dehydrogenase subunit N NP_223912.1 1325417 D 85963 CDS NP_223913.1 15612260 889830 1326885..1329296 1 NC_000921.1 similar to H. pylori 26695 gene HP1274; flagellar functional protein 1329296 pflA 889830 pflA Helicobacter pylori J99 flagellar functional protein NP_223913.1 1326885 D 85963 CDS NP_223914.1 15612261 890445 1329298..1330677 1 NC_000921.1 similar to H. pylori 26695 gene HP1275; phosphomannomutase 1330677 890445 jhp1196 Helicobacter pylori J99 phosphomannomutase NP_223914.1 1329298 D 85963 CDS NP_223915.1 15612262 889825 1330858..1331229 1 NC_000921.1 similar to H. pylori 26695 gene HP1276; hypothetical protein 1331229 889825 jhp1197 Helicobacter pylori J99 hypothetical protein NP_223915.1 1330858 D 85963 CDS NP_223916.1 15612263 890451 complement(1331406..1332194) 1 NC_000921.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1332194 trpA 890451 trpA Helicobacter pylori J99 tryptophan synthase subunit alpha NP_223916.1 1331406 R 85963 CDS NP_223917.1 15612264 889826 complement(1332191..1333372) 1 NC_000921.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1333372 trpB 889826 trpB Helicobacter pylori J99 tryptophan synthase subunit beta NP_223917.1 1332191 R 85963 CDS NP_223918.1 15612265 890448 complement(1333374..1334732) 1 NC_000921.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1334732 trpC 890448 trpC Helicobacter pylori J99 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase NP_223918.1 1333374 R 85963 CDS NP_223919.1 15612266 889827 complement(1334725..1335732) 1 NC_000921.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1335732 trpD 889827 trpD Helicobacter pylori J99 anthranilate phosphoribosyltransferase NP_223919.1 1334725 R 85963 CDS NP_223920.1 15612267 890454 complement(1335729..1336313) 1 NC_000921.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1336313 trpG 890454 trpG Helicobacter pylori J99 anthranilate synthase component II NP_223920.1 1335729 R 85963 CDS NP_223921.1 15612268 889828 complement(1336310..1337812) 1 NC_000921.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1337812 trpE 889828 trpE Helicobacter pylori J99 anthranilate synthase component I NP_223921.1 1336310 R 85963 CDS NP_223922.1 15612269 890450 complement(1338041..1339099) 1 NC_000921.1 similar to H. pylori 26695 gene HP1284; hypothetical protein 1339099 890450 jhp1204 Helicobacter pylori J99 hypothetical protein NP_223922.1 1338041 R 85963 CDS NP_223923.1 15612270 889863 complement(1339167..1339904) 1 NC_000921.1 similar to H. pylori 26695 gene HP1285; hypothetical protein 1339904 889863 jhp1205 Helicobacter pylori J99 hypothetical protein NP_223923.1 1339167 R 85963 CDS NP_223924.1 15612271 890389 1340027..1340575 1 NC_000921.1 similar to H. pylori 26695 gene HP1286; hypothetical protein 1340575 890389 jhp1206 Helicobacter pylori J99 hypothetical protein NP_223924.1 1340027 D 85963 CDS NP_223925.1 15612272 889829 complement(1340639..1341292) 1 NC_000921.1 similar to H. pylori 26695 gene HP1287; transcriptional regulator 1341292 889829 jhp1207 Helicobacter pylori J99 transcriptional regulator NP_223925.1 1340639 R 85963 CDS NP_223926.1 15612273 890446 1342003..1342356 1 NC_000921.1 similar to H. pylori 26695 gene HP1288; hypothetical protein 1342356 890446 jhp1208 Helicobacter pylori J99 hypothetical protein NP_223926.1 1342003 D 85963 CDS NP_223927.1 15612274 889831 1342380..1342865 1 NC_000921.1 similar to H. pylori 26695 gene HP1289; hypothetical protein 1342865 889831 jhp1209 Helicobacter pylori J99 hypothetical protein NP_223927.1 1342380 D 85963 CDS NP_223928.1 15612275 890442 1343051..1343713 1 NC_000921.1 similar to H. pylori 26695 gene HP1290; nicotinamide mononucleotide transporter 1343713 pnuC 890442 pnuC Helicobacter pylori J99 nicotinamide mononucleotide transporter NP_223928.1 1343051 D 85963 CDS NP_223929.1 15612276 889834 1343701..1344315 1 NC_000921.1 similar to H. pylori 26695 gene HP1291; hypothetical protein 1344315 889834 jhp1211 Helicobacter pylori J99 hypothetical protein NP_223929.1 1343701 D 85963 CDS NP_223930.1 15612277 890439 complement(1345094..1345444) 1 NC_000921.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1345444 rplQ 890439 rplQ Helicobacter pylori J99 50S ribosomal protein L17 NP_223930.1 1345094 R 85963 CDS NP_223931.1 15612278 889832 complement(1345444..1346478) 1 NC_000921.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1346478 rpoA 889832 rpoA Helicobacter pylori J99 DNA-directed RNA polymerase subunit alpha NP_223931.1 1345444 R 85963 CDS NP_223932.1 15612279 890434 complement(1346490..1347116) 1 NC_000921.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1347116 rpsD 890434 rpsD Helicobacter pylori J99 30S ribosomal protein S4 NP_223932.1 1346490 R 85963 CDS NP_223933.1 15612280 889842 complement(1347126..1347521) 1 NC_000921.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1347521 rpsK 889842 rpsK Helicobacter pylori J99 30S ribosomal protein S11 NP_223933.1 1347126 R 85963 CDS NP_223934.1 15612281 890423 complement(1347544..1347906) 1 NC_000921.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1347906 rpsM 890423 rpsM Helicobacter pylori J99 30S ribosomal protein S13 NP_223934.1 1347544 R 85963 CDS NP_223935.1 15612282 889833 complement(1347910..1348023) 1 NC_000921.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1348023 rpmJ 889833 rpmJ Helicobacter pylori J99 50S ribosomal protein L36 NP_223935.1 1347910 R 85963 CDS NP_223936.1 15612283 890438 complement(1348102..1348320) 1 NC_000921.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1348320 infA 890438 infA Helicobacter pylori J99 translation initiation factor IF-1 NP_223936.1 1348102 R 85963 CDS NP_223937.1 15612284 889835 complement(1348320..1349081) 1 NC_000921.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1349081 map 889835 map Helicobacter pylori J99 methionine aminopeptidase NP_223937.1 1348320 R 85963 CDS NP_223938.1 15612285 890436 complement(1349081..1350343) 1 NC_000921.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1350343 secY 890436 secY Helicobacter pylori J99 preprotein translocase subunit SecY NP_223938.1 1349081 R 85963 CDS NP_223939.1 15612286 889836 complement(1350378..1350779) 1 NC_000921.1 late assembly protein; 50S ribosomal protein L15 1350779 rplO 889836 rplO Helicobacter pylori J99 50S ribosomal protein L15 NP_223939.1 1350378 R 85963 CDS NP_223940.2 394893783 890433 complement(1350797..1351240) 1 NC_000921.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1351240 rpsE 890433 rpsE Helicobacter pylori J99 30S ribosomal protein S5 NP_223940.2 1350797 R 85963 CDS NP_223941.1 15612288 889837 complement(1351255..1351611) 1 NC_000921.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1351611 rplR 889837 rplR Helicobacter pylori J99 50S ribosomal protein L18 NP_223941.1 1351255 R 85963 CDS NP_223942.1 15612289 890435 complement(1351625..1352161) 1 NC_000921.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1352161 rplF 890435 rplF Helicobacter pylori J99 50S ribosomal protein L6 NP_223942.1 1351625 R 85963 CDS NP_223943.1 15612290 889838 complement(1352173..1352568) 1 NC_000921.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1352568 rpsH 889838 rpsH Helicobacter pylori J99 30S ribosomal protein S8 NP_223943.1 1352173 R 85963 CDS NP_223944.1 15612291 890431 complement(1352578..1352763) 1 NC_000921.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 1352763 rpsN 890431 rpsN Helicobacter pylori J99 30S ribosomal protein S14 NP_223944.1 1352578 R 85963 CDS NP_223945.1 15612292 889839 complement(1352773..1353318) 1 NC_000921.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1353318 rplE 889839 rplE Helicobacter pylori J99 50S ribosomal protein L5 NP_223945.1 1352773 R 85963 CDS NP_223946.1 15612293 890426 complement(1353332..1353553) 1 NC_000921.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1353553 rplX 890426 rplX Helicobacter pylori J99 50S ribosomal protein L24 NP_223946.1 1353332 R 85963 CDS NP_223947.1 15612294 889840 complement(1353553..1353921) 1 NC_000921.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1353921 rplN 889840 rplN Helicobacter pylori J99 50S ribosomal protein L14 NP_223947.1 1353553 R 85963 CDS NP_223948.1 15612295 890420 complement(1353924..1354184) 1 NC_000921.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1354184 rpsQ 890420 rpsQ Helicobacter pylori J99 30S ribosomal protein S17 NP_223948.1 1353924 R 85963 CDS NP_223949.1 15612296 889841 complement(1354198..1354398) 1 NC_000921.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1354398 rpmC 889841 rpmC Helicobacter pylori J99 50S ribosomal protein L29 NP_223949.1 1354198 R 85963 CDS NP_223950.1 15612297 890424 complement(1354385..1354810) 1 NC_000921.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1354810 rplP 890424 rplP Helicobacter pylori J99 50S ribosomal protein L16 NP_223950.1 1354385 R 85963 CDS NP_223951.1 15612298 889843 complement(1354813..1355517) 1 NC_000921.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1355517 rpsC 889843 rpsC Helicobacter pylori J99 30S ribosomal protein S3 NP_223951.1 1354813 R 85963 CDS NP_223952.1 15612299 890421 complement(1355521..1355889) 1 NC_000921.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1355889 rplV 890421 rplV Helicobacter pylori J99 50S ribosomal protein L22 NP_223952.1 1355521 R 85963 CDS NP_223953.1 15612300 889851 complement(1355899..1356180) 1 NC_000921.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1356180 rpsS 889851 rpsS Helicobacter pylori J99 30S ribosomal protein S19 NP_223953.1 1355899 R 85963 CDS NP_223954.1 15612301 889844 complement(1356192..1357022) 1 NC_000921.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1357022 rplB 889844 rplB Helicobacter pylori J99 50S ribosomal protein L2 NP_223954.1 1356192 R 85963 CDS NP_223955.1 15612302 890422 complement(1357038..1357319) 1 NC_000921.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1357319 rplW 890422 rplW Helicobacter pylori J99 50S ribosomal protein L23 NP_223955.1 1357038 R 85963 CDS NP_223956.1 15612303 889845 complement(1357323..1357970) 1 NC_000921.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1357970 rplD 889845 rplD Helicobacter pylori J99 50S ribosomal protein L4 NP_223956.1 1357323 R 85963 CDS NP_223957.1 15612304 890418 complement(1358005..1358580) 1 NC_000921.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1358580 rplC 890418 rplC Helicobacter pylori J99 50S ribosomal protein L3 NP_223957.1 1358005 R 85963 CDS NP_223958.1 15612305 889846 complement(1358617..1358931) 1 NC_000921.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1358931 rpsJ 889846 rpsJ Helicobacter pylori J99 30S ribosomal protein S10 NP_223958.1 1358617 R 85963 CDS NP_223959.1 15612306 890416 1359097..1360227 1 NC_000921.1 similar to H. pylori 26695 gene HP1321; hypothetical protein 1360227 890416 jhp1241 Helicobacter pylori J99 hypothetical protein NP_223959.1 1359097 D 85963 CDS NP_223960.1 15612307 889847 1360492..1361070 1 NC_000921.1 similar to H. pylori 26695 gene HP1322; hypothetical protein 1361070 889847 jhp1242 Helicobacter pylori J99 hypothetical protein NP_223960.1 1360492 D 85963 CDS NP_223961.1 15612308 890412 complement(1361044..1361673) 1 NC_000921.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1361673 rnhB 890412 rnhB Helicobacter pylori J99 ribonuclease HII NP_223961.1 1361044 R 85963 CDS NP_223962.1 15612309 889848 complement(1361689..1361883) 1 NC_000921.1 similar to H. pylori 26695 gene HP1324; hypothetical protein 1361883 889848 jhp1244 Helicobacter pylori J99 hypothetical protein NP_223962.1 1361689 R 85963 CDS NP_223963.1 15612310 890413 complement(1361964..1363355) 1 NC_000921.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1363355 fumC 890413 fumC Helicobacter pylori J99 fumarate hydratase NP_223963.1 1361964 R 85963 CDS NP_223964.1 15612311 889849 1363530..1363907 1 NC_000921.1 similar to H. pylori 26695 gene HP1326; hypothetical protein 1363907 889849 jhp1246 Helicobacter pylori J99 hypothetical protein NP_223964.1 1363530 D 85963 CDS NP_223965.1 15612312 890399 1363912..1365150 1 NC_000921.1 similar to H. pylori 26695 gene HP1327; hypothetical protein 1365150 890399 jhp1247 Helicobacter pylori J99 hypothetical protein NP_223965.1 1363912 D 85963 CDS NP_223966.1 15612313 889850 1365147..1366172 1 NC_000921.1 similar to H. pylori 26695 gene HP1328; cation efflux system protein 1366172 czcB_2 889850 czcB_2 Helicobacter pylori J99 cation efflux system protein NP_223966.1 1365147 D 85963 CDS NP_223967.1 15612314 890409 1366173..1369280 1 NC_000921.1 similar to H. pylori 26695 gene HP1329; cation efflux system protein 1369280 czcA_2 890409 czcA_2 Helicobacter pylori J99 cation efflux system protein NP_223967.1 1366173 D 85963 CDS NP_223968.1 15612315 889852 complement(1369261..1369617) 1 NC_000921.1 similar to H. pylori 26695 gene HP1330; hypothetical protein 1369617 889852 jhp1250 Helicobacter pylori J99 hypothetical protein NP_223968.1 1369261 R 85963 CDS NP_223969.1 15612316 890407 complement(1369611..1370297) 1 NC_000921.1 similar to H. pylori 26695 gene HP1331; hypothetical protein 1370297 890407 jhp1251 Helicobacter pylori J99 hypothetical protein NP_223969.1 1369611 R 85963 CDS NP_223970.1 15612317 889855 complement(1370308..1371417) 1 NC_000921.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 1371417 dnaJ_2 889855 dnaJ_2 Helicobacter pylori J99 molecular chaperone DnaJ NP_223970.1 1370308 R 85963 CDS NP_223971.1 15612318 890402 1371542..1372672 1 NC_000921.1 similar to H. pylori 26695 gene HP1333; hypothetical protein 1372672 890402 jhp1253 Helicobacter pylori J99 hypothetical protein NP_223971.1 1371542 D 85963 CDS NP_223972.2 161353441 889853 complement(1372714..1373742) 1 NC_000921.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1373742 mnmA 889853 mnmA Helicobacter pylori J99 tRNA-specific 2-thiouridylase MnmA NP_223972.2 1372714 R 85963 CDS NP_223973.1 15612320 890408 1373882..1374643 1 NC_000921.1 similar to H. pylori 26695 gene HP1336; hypothetical protein 1374643 890408 jhp1255 Helicobacter pylori J99 hypothetical protein NP_223973.1 1373882 D 85963 CDS NP_223974.1 15612321 889854 complement(1374640..1375164) 1 NC_000921.1 similar to H. pylori 26695 gene HP1337; hypothetical protein 1375164 889854 jhp1256 Helicobacter pylori J99 hypothetical protein NP_223974.1 1374640 R 85963 CDS NP_223975.1 15612322 890405 complement(1375148..1375594) 1 NC_000921.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 1375594 890405 jhp1257 Helicobacter pylori J99 nickel responsive regulator NP_223975.1 1375148 R 85963 CDS NP_223976.1 15612323 889860 1375917..1376354 1 NC_000921.1 similar to H. pylori 26695 gene HP1339; biopolymer transport protein 1376354 exbB_2 889860 exbB_2 Helicobacter pylori J99 biopolymer transport protein NP_223976.1 1375917 D 85963 CDS NP_223977.1 15612324 890397 1376351..1376740 1 NC_000921.1 similar to H. pylori 26695 gene HP1340; biopolymer transport EXBD protein 1376740 exbD_2 890397 exbD_2 Helicobacter pylori J99 biopolymer transport EXBD protein NP_223977.1 1376351 D 85963 CDS NP_223978.1 15612325 889856 1376706..1377548 1 NC_000921.1 similar to H. pylori 26695 gene HP1341; siderophore-mediated iron transport protein 1377548 tonB_2 889856 tonB_2 Helicobacter pylori J99 siderophore-mediated iron transport protein NP_223978.1 1376706 D 85963 CDS NP_223979.1 15612326 890404 1377733..1379823 1 NC_000921.1 similar to H. pylori 26695 gene HP1342; hypothetical protein 1379823 890404 jhp1261 Helicobacter pylori J99 hypothetical protein NP_223979.1 1377733 D 85963 CDS NP_223980.1 15612327 889857 complement(1379941..1380669) 1 NC_000921.1 similar to H. pylori 26695 gene HP1343; hypothetical protein 1380669 889857 jhp1262 Helicobacter pylori J99 hypothetical protein NP_223980.1 1379941 R 85963 CDS NP_223981.1 15612328 890398 complement(1380676..1381632) 1 NC_000921.1 similar to H. pylori 26695 gene HP1344; magnesium/cobalt transporter CorA 1381632 corA 890398 corA Helicobacter pylori J99 magnesium/cobalt transporter CorA NP_223981.1 1380676 R 85963 CDS NP_223982.1 15612329 889858 complement(1381648..1382856) 1 NC_000921.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1382856 pgk 889858 pgk Helicobacter pylori J99 phosphoglycerate kinase NP_223982.1 1381648 R 85963 CDS NP_223983.1 15612330 890401 complement(1382871..1383863) 1 NC_000921.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1383863 gap_2 890401 gap_2 Helicobacter pylori J99 glyceraldehyde-3-phosphate dehydrogenase NP_223983.1 1382871 R 85963 CDS NP_223984.1 15612331 889882 complement(1383952..1384653) 1 NC_000921.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1384653 ung 889882 ung Helicobacter pylori J99 uracil-DNA glycosylase NP_223984.1 1383952 R 85963 CDS NP_223985.1 15612332 889510 complement(1384650..1385363) 1 NC_000921.1 similar to H. pylori 26695 gene HP1348; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1385363 plsC 889510 plsC Helicobacter pylori J99 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_223985.1 1384650 R 85963 CDS NP_223986.1 15612333 889859 complement(1385350..1386513) 1 NC_000921.1 similar to H. pylori 26695 gene HP1349; hypothetical protein 1386513 889859 jhp1268 Helicobacter pylori J99 hypothetical protein NP_223986.1 1385350 R 85963 CDS NP_223987.1 15612334 890400 complement(1386520..1387899) 1 NC_000921.1 similar to H. pylori 26695 gene HP1350; carboxyl-terminal protease 1387899 prc 890400 prc Helicobacter pylori J99 carboxyl-terminal protease NP_223987.1 1386520 R 85963 CDS NP_223988.1 15612335 889861 complement(1388109..1388981) 1 NC_000921.1 similar to H. pylori 26695 gene HP1351; hypothetical protein 1388981 889861 jhp1270 Helicobacter pylori J99 hypothetical protein NP_223988.1 1388109 R 85963 CDS NP_223989.1 15612336 890394 complement(1388981..1390060) 1 NC_000921.1 similar to H. pylori 26695 gene HP1352; type II DNA modification (methyltransferase 1390060 890394 jhp1271 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_223989.1 1388981 R 85963 CDS NP_223990.1 15612337 889862 complement(join(1390189..1390483,1390483..1391310,1391310..1393681)) 1 NC_000921.1 similar to TIGR HP1354; expression of this protein is predicted to be regulated by slipped-strand repair at the two (C) polynucleotide repeats; length of both repeats has been artificially adjusted (addition of one nucleotide in both cases) to give the full length protein; hypothetical protein 1393681 889862 jhp1272 Helicobacter pylori J99 hypothetical protein NP_223990.1 1390189 R 85963 CDS NP_223991.1 15612338 890391 complement(1393792..1394613) 1 NC_000921.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1394613 nadC 890391 nadC Helicobacter pylori J99 nicotinate-nucleotide pyrophosphorylase NP_223991.1 1393792 R 85963 CDS NP_223992.1 15612339 889864 complement(1394613..1395623) 1 NC_000921.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1395623 nadA 889864 nadA Helicobacter pylori J99 quinolinate synthetase NP_223992.1 1394613 R 85963 CDS NP_223993.1 15612340 890390 complement(1395613..1396416) 1 NC_000921.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 1396416 psd 890390 psd Helicobacter pylori J99 phosphatidylserine decarboxylase NP_223993.1 1395613 R 85963 CDS NP_223994.1 15612341 889865 complement(1396410..1396916) 1 NC_000921.1 similar to H. pylori 26695 gene HP1358; hypothetical protein 1396916 889865 jhp1276 Helicobacter pylori J99 hypothetical protein NP_223994.1 1396410 R 85963 CDS NP_223995.1 15612342 890387 complement(1396929..1397480) 1 NC_000921.1 similar to H. pylori 26695 gene HP1359; hypothetical protein 1397480 890387 jhp1277 Helicobacter pylori J99 hypothetical protein NP_223995.1 1396929 R 85963 CDS NP_223996.1 15612343 889866 complement(1397416..1398300) 1 NC_000921.1 UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 1398300 ubiA 889866 ubiA Helicobacter pylori J99 prenyltransferase NP_223996.1 1397416 R 85963 CDS NP_223997.1 15612344 890386 complement(1398329..1399558) 1 NC_000921.1 similar to H. pylori 26695 gene HP1361; DNA transfer protein 1399558 comEC 890386 comEC Helicobacter pylori J99 DNA transfer protein NP_223997.1 1398329 R 85963 CDS NP_223998.1 15612345 889867 complement(1399639..1401099) 1 NC_000921.1 unwinds double stranded DNA; replicative DNA helicase 1401099 dnaB 889867 dnaB Helicobacter pylori J99 replicative DNA helicase NP_223998.1 1399639 R 85963 CDS NP_223999.1 15612346 890380 complement(1401110..1402504) 1 NC_000921.1 similar to H. pylori 26695 gene HP1363; hypothetical protein 1402504 890380 jhp1281 Helicobacter pylori J99 hypothetical protein NP_223999.1 1401110 R 85963 CDS NP_224000.1 15612347 889875 complement(1402507..1403541) 1 NC_000921.1 similar to H. pylori 26695 gene HP1364; histidine kinase sensor protein 1403541 889875 jhp1282 Helicobacter pylori J99 histidine kinase sensor protein NP_224000.1 1402507 R 85963 CDS NP_224001.1 15612348 890366 complement(1403675..1404316) 1 NC_000921.1 similar to H. pylori 26695 gene HP1365; transcriptional regulator 1404316 890366 jhp1283 Helicobacter pylori J99 transcriptional regulator NP_224001.1 1403675 R 85963 CDS NP_224002.1 15612349 889868 1404425..1406374 1 NC_000921.1 type II DNA modification (methyltransferase 1406374 889868 jhp1284 Helicobacter pylori J99 type II DNA modification (methyltransferase NP_224002.1 1404425 D 85963 CDS NP_224003.1 15612350 890382 1406384..1409302 1 NC_000921.1 similar to H. pylori 26695 gene HP1371; type III restriction enzyme R protein 1409302 890382 jhp1285 Helicobacter pylori J99 type III restriction enzyme R protein NP_224003.1 1406384 D 85963 CDS NP_224004.1 15612351 889869 complement(1409352..1410098) 1 NC_000921.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1410098 889869 jhp1286 Helicobacter pylori J99 rod shape-determining protein MreC NP_224004.1 1409352 R 85963 CDS NP_224005.1 15612352 890379 complement(1410102..1411145) 1 NC_000921.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1411145 mreB 890379 mreB Helicobacter pylori J99 rod shape-determining protein MreB NP_224005.1 1410102 R 85963 CDS NP_224006.1 15612353 889870 complement(1411198..1412556) 1 NC_000921.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1412556 clpX 889870 clpX Helicobacter pylori J99 ATP-dependent protease ATP-binding subunit ClpX NP_224006.1 1411198 R 85963 CDS NP_224007.1 15612354 890374 complement(1412558..1413370) 1 NC_000921.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1413370 lpxA 890374 lpxA Helicobacter pylori J99 UDP-N-acetylglucosamine acyltransferase NP_224007.1 1412558 R 85963 CDS NP_224008.1 15612355 889871 complement(1413373..1413852) 1 NC_000921.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1413852 fabZ 889871 fabZ Helicobacter pylori J99 (3R)-hydroxymyristoyl-ACP dehydratase NP_224008.1 1413373 R 85963 CDS NP_224009.1 15612356 890371 complement(1414034..1414423) 1 NC_000921.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1414423 890371 jhp1291 Helicobacter pylori J99 flagellar assembly protein FliW NP_224009.1 1414034 R 85963 CDS NP_224010.1 15612357 889872 1414826..1415488 1 NC_000921.1 similar to H. pylori 26695 gene HP1378; hypothetical protein 1415488 889872 jhp1292 Helicobacter pylori J99 hypothetical protein NP_224010.1 1414826 D 85963 CDS NP_224011.1 15612358 890375 1415531..1418026 1 NC_000921.1 similar to H. pylori 26695 gene HP1379; ATP-dependent protease LA 1418026 lon 890375 lon Helicobacter pylori J99 ATP-dependent protease LA NP_224011.1 1415531 D 85963 CDS NP_224012.1 15612359 889873 1418035..1418862 1 NC_000921.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1418862 tyrA 889873 tyrA Helicobacter pylori J99 prephenate dehydrogenase NP_224012.1 1418035 D 85963 CDS NP_224013.1 15612360 890373 complement(1419313..1420176) 1 NC_000921.1 similar to H. pylori 26695 gene HP1382; endonuclease 1420176 890373 jhp1295 Helicobacter pylori J99 endonuclease NP_224013.1 1419313 R 85963 CDS NP_224014.1 15612361 889877 complement(1420437..1422299) 1 NC_000921.1 type III DNA modification enzyme 1422299 mod_1 889877 mod_1 Helicobacter pylori J99 type III DNA modification enzyme NP_224014.1 1420437 R 85963 CDS NP_224015.1 15612362 890364 complement(1422293..1424632) 1 NC_000921.1 type III restriction enzyme 1424632 res_1 890364 res_1 Helicobacter pylori J99 type III restriction enzyme NP_224015.1 1422293 R 85963 CDS NP_224016.1 15612363 889874 1425041..1425889 1 NC_000921.1 catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1425889 bioB 889874 bioB Helicobacter pylori J99 biotin synthase NP_224016.1 1425041 D 85963 CDS NP_224017.1 15612364 890369 1425889..1426767 1 NC_000921.1 similar to H. pylori 26695 gene HP1407; ribonuclease N 1426767 rbn 890369 rbn Helicobacter pylori J99 ribonuclease N NP_224017.1 1425889 D 85963 CDS NP_224018.1 15612365 889878 1430913..1431449 1 NC_000921.1 similar to H. pylori 26695 gene HP1408; hypothetical protein 1431449 889878 jhp1300 Helicobacter pylori J99 hypothetical protein NP_224018.1 1430913 D 85963 CDS NP_224019.1 15612366 890360 1431394..1432338 1 NC_000921.1 similar to H. pylori 26695 gene HP1409; hypothetical protein 1432338 890360 jhp1301 Helicobacter pylori J99 hypothetical protein NP_224019.1 1431394 D 85963 CDS NP_224020.1 15612367 889876 1432520..1433125 1 NC_000921.1 similar to H. pylori 26695 gene HP1409; hypothetical protein 1433125 889876 jhp1302 Helicobacter pylori J99 hypothetical protein NP_224020.1 1432520 D 85963 CDS NP_224021.1 15612368 890367 1433171..1434403 1 NC_000921.1 similar to H. pylori 26695 gene HP1410; hypothetical protein 1434403 890367 jhp1303 Helicobacter pylori J99 hypothetical protein NP_224021.1 1433171 D 85963 CDS NP_224022.1 15612369 889879 1434471..1435400 1 NC_000921.1 similar to H. pylori 26695 gene HP1411; hypothetical protein 1435400 889879 jhp1304 Helicobacter pylori J99 hypothetical protein NP_224022.1 1434471 D 85963 CDS NP_224023.1 15612370 890363 1435587..1436318 1 NC_000921.1 similar to H. pylori 26695 gene HP1411; hypothetical protein 1436318 890363 jhp1305 Helicobacter pylori J99 hypothetical protein NP_224023.1 1435587 D 85963 CDS NP_224024.1 15612371 889880 1436452..1436607 1 NC_000921.1 hypothetical protein 1436607 889880 jhp1306 Helicobacter pylori J99 hypothetical protein NP_224024.1 1436452 D 85963 CDS NP_224025.1 15612372 890361 1436642..1437364 1 NC_000921.1 similar to H. pylori 26695 gene HP1412; hypothetical protein 1437364 890361 jhp1307 Helicobacter pylori J99 hypothetical protein NP_224025.1 1436642 D 85963 CDS NP_224026.1 15612373 889881 complement(1437494..1437940) 1 NC_000921.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1437940 889881 jhp1308 Helicobacter pylori J99 7-cyano-7-deazaguanine reductase NP_224026.1 1437494 R 85963 CDS NP_224027.1 15612374 889451 1437999..1438340 1 NC_000921.1 similar to H. pylori 26695 gene HP1414; hypothetical protein 1438340 889451 jhp1309 Helicobacter pylori J99 hypothetical protein NP_224027.1 1437999 D 85963 CDS NP_224028.1 15612375 889884 1438411..1439244 1 NC_000921.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1439244 miaA 889884 miaA Helicobacter pylori J99 tRNA delta(2)-isopentenylpyrophosphate transferase NP_224028.1 1438411 D 85963 CDS NP_224029.1 15612376 889355 1439245..1440348 1 NC_000921.1 similar to H. pylori 26695 gene HP1416; lipopolysaccharide biosynthesis protein 1440348 889355 jhp1311 Helicobacter pylori J99 lipopolysaccharide biosynthesis protein NP_224029.1 1439245 D 85963 CDS NP_224030.1 15612377 889883 join(1440365..1441149,1441148..1442024) 1 NC_000921.1 similar to TIGR HP1417; expression of this protein is predicted to be regulated by slipped-strand repair at the (AG) dinucleotide repeat; length of the repeat has been artificially adjusted (addition of one dinucleotide) to give the full length protein; hypothetical protein 1442024 889883 jhp1312 Helicobacter pylori J99 hypothetical protein NP_224030.1 1440365 D 85963 CDS NP_224031.1 15612378 889470 complement(1442085..1442864) 1 NC_000921.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1442864 murB 889470 murB Helicobacter pylori J99 UDP-N-acetylenolpyruvoylglucosamine reductase NP_224031.1 1442085 R 85963 CDS NP_224032.1 15612379 889895 complement(1442868..1443134) 1 NC_000921.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1443134 fliQ 889895 fliQ Helicobacter pylori J99 flagellar biosynthesis protein FliQ NP_224032.1 1442868 R 85963 CDS NP_224033.1 15612380 889885 complement(1443145..1444449) 1 NC_000921.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1444449 fliI 889885 fliI Helicobacter pylori J99 flagellum-specific ATP synthase NP_224033.1 1443145 R 85963 CDS NP_224034.1 15612381 889350 complement(1444450..1445364) 1 NC_000921.1 similar to H. pylori 26695 gene HP1421; DNA transfer protein 1445364 virB11_2 889350 virB11_2 Helicobacter pylori J99 DNA transfer protein NP_224034.1 1444450 R 85963 CDS NP_224035.1 15612382 889886 complement(1445381..1448143) 1 NC_000921.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1448143 ileS 889886 ileS Helicobacter pylori J99 isoleucyl-tRNA synthetase NP_224035.1 1445381 R 85963 CDS NP_224036.1 15612383 889404 complement(1448163..1448417) 1 NC_000921.1 similar to H. pylori 26695 gene HP1423; hypothetical protein 1448417 889404 jhp1318 Helicobacter pylori J99 hypothetical protein NP_224036.1 1448163 R 85963 CDS NP_224037.1 15612384 889887 1448519..1449139 1 NC_000921.1 similar to H. pylori 26695 gene HP1424; hypothetical protein 1449139 889887 jhp1319 Helicobacter pylori J99 hypothetical protein NP_224037.1 1448519 D 85963 CDS NP_224038.1 15612385 889511 complement(1449374..1449556) 1 NC_000921.1 similar to H. pylori 26695 gene HP1427; histidine-rich metal-binding protein 1449556 889511 jhp1320 Helicobacter pylori J99 histidine-rich metal-binding protein NP_224038.1 1449374 R 85963 CDS NP_224039.1 15612386 889890 complement(1449828..1450061) 1 NC_000921.1 similar to H. pylori 26695 gene HP1432; histidine and glutamine-rich metal-binding protein 1450061 889890 jhp1321 Helicobacter pylori J99 histidine and glutamine-rich metal-binding protein NP_224039.1 1449828 R 85963 CDS NP_224040.1 15612387 889463 1450314..1451129 1 NC_000921.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1451129 ksgA 889463 ksgA Helicobacter pylori J99 dimethyladenosine transferase NP_224040.1 1450314 D 85963 CDS NP_224041.1 15612388 889888 1451180..1453258 1 NC_000921.1 similar to H. pylori 26695 gene HP1430; hypothetical protein 1453258 889888 jhp1323 Helicobacter pylori J99 hypothetical protein NP_224041.1 1451180 D 85963 CDS NP_224042.1 15612389 889434 1453242..1454231 1 NC_000921.1 similar to H. pylori 26695 gene HP1429; hypothetical protein 1454231 889434 jhp1324 Helicobacter pylori J99 hypothetical protein NP_224042.1 1453242 D 85963 CDS NP_224043.1 15612390 889889 1454228..1455301 1 NC_000921.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1455301 889889 jhp1325 Helicobacter pylori J99 ribosomal RNA large subunit methyltransferase N NP_224043.1 1454228 D 85963 CDS NP_224044.1 15612391 889421 complement(1456084..1458462) 1 NC_000921.1 similar to H. pylori 26695 gene HP1433; hypothetical protein 1458462 889421 jhp1326 Helicobacter pylori J99 hypothetical protein NP_224044.1 1456084 R 85963 CDS NP_224045.1 15612392 889891 complement(1458571..1459452) 1 NC_000921.1 similar to H. pylori 26695 gene HP1434; formyltetrahydrofolate hydrolase 1459452 purU 889891 purU Helicobacter pylori J99 formyltetrahydrofolate hydrolase NP_224045.1 1458571 R 85963 CDS NP_224046.1 15612393 889493 complement(1459455..1460333) 1 NC_000921.1 similar to H. pylori 26695 gene HP1435; endopeptidase IV 1460333 sppA 889493 sppA Helicobacter pylori J99 endopeptidase IV NP_224046.1 1459455 R 85963 CDS NP_224047.1 15612394 889892 1460404..1460664 1 NC_000921.1 similar to H. pylori 26695 gene HP1436; hypothetical protein 1460664 889892 jhp1329 Helicobacter pylori J99 hypothetical protein NP_224047.1 1460404 D 85963 CDS NP_224048.1 15612395 889578 1460871..1461434 1 NC_000921.1 similar to H. pylori 26695 gene HP1437; hypothetical protein 1461434 889578 jhp1330 Helicobacter pylori J99 hypothetical protein NP_224048.1 1460871 D 85963 CDS NP_224049.1 15612396 889893 1461570..1462055 1 NC_000921.1 similar to H. pylori 26695 gene HP1438; hypothetical protein 1462055 889893 jhp1331 Helicobacter pylori J99 hypothetical protein NP_224049.1 1461570 D 85963 CDS NP_224050.1 15612397 889896 1462065..1462490 1 NC_000921.1 similar to H. pylori 26695 gene HP1439; hypothetical protein 1462490 889896 jhp1332 Helicobacter pylori J99 hypothetical protein NP_224050.1 1462065 D 85963 CDS NP_224051.1 15612398 889900 complement(1465043..1465822) 1 NC_000921.1 similar to H. pylori 26695 gene HP1440; hypothetical protein 1465822 889900 jhp1333 Helicobacter pylori J99 hypothetical protein NP_224051.1 1465043 R 85963 CDS NP_224052.1 15612399 889894 1465946..1466434 1 NC_000921.1 similar to H. pylori 26695 gene HP1441; peptidyl-prolyl cis-trans isomerase 1466434 ppiA 889894 ppiA Helicobacter pylori J99 peptidyl-prolyl cis-trans isomerase NP_224052.1 1465946 D 85963 CDS NP_224053.1 15612400 889897 1466452..1466682 1 NC_000921.1 affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1466682 csrA 889897 csrA Helicobacter pylori J99 carbon storage regulator NP_224053.1 1466452 D 85963 CDS NP_224054.1 15612401 889898 1466679..1467503 1 NC_000921.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1467503 889898 jhp1336 Helicobacter pylori J99 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_224054.1 1466679 D 85963 CDS NP_224055.1 15612402 889901 1467481..1467939 1 NC_000921.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1467939 smpB 889901 smpB Helicobacter pylori J99 SsrA-binding protein NP_224055.1 1467481 D 85963 CDS NP_224056.1 15612403 889906 1467942..1468394 1 NC_000921.1 similar to H. pylori 26695 gene HP1445; biopolymer transport protein 1468394 exbB_3 889906 exbB_3 Helicobacter pylori J99 biopolymer transport protein NP_224056.1 1467942 D 85963 CDS NP_224057.1 15612404 889899 1468405..1468806 1 NC_000921.1 similar to H. pylori 26695 gene HP1446; biopolymer transport protein 1468806 exbD_3 889899 exbD_3 Helicobacter pylori J99 biopolymer transport protein NP_224057.1 1468405 D 85963 CDS NP_224058.1 15612405 889902 1468878..1469012 1 NC_000921.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1469012 rpmH 889902 rpmH Helicobacter pylori J99 50S ribosomal protein L34 NP_224058.1 1468878 D 85963 CDS NP_224059.1 15612406 889904 1468972..1469457 1 NC_000921.1 similar to H. pylori 26695 gene HP1448; ribonuclease P protein component 1469457 rnpA 889904 rnpA Helicobacter pylori J99 ribonuclease P protein component NP_224059.1 1468972 D 85963 CDS NP_224060.1 15612407 889929 1469444..1469800 1 NC_000921.1 similar to H. pylori 26695 gene HP1449; hypothetical protein 1469800 889929 jhp1342 Helicobacter pylori J99 hypothetical protein NP_224060.1 1469444 D 85963 CDS NP_224061.1 15612408 889903 1469806..1471455 1 NC_000921.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1471455 889903 jhp1343 Helicobacter pylori J99 inner membrane protein translocase component YidC NP_224061.1 1469806 D 85963 CDS NP_224062.1 15612409 889919 1471469..1472245 1 NC_000921.1 similar to H. pylori 26695 gene HP1451; hypothetical protein 1472245 889919 jhp1344 Helicobacter pylori J99 hypothetical protein NP_224062.1 1471469 D 85963 CDS NP_224063.1 15612410 889915 1472205..1473590 1 NC_000921.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1473590 trmE 889915 trmE Helicobacter pylori J99 tRNA modification GTPase TrmE NP_224063.1 1472205 D 85963 CDS NP_224064.1 15612411 889905 1473792..1476026 1 NC_000921.1 similar to H. pylori 26695 gene HP1453; hypothetical protein 1476026 889905 jhp1346 Helicobacter pylori J99 hypothetical protein NP_224064.1 1473792 D 85963 CDS NP_224065.1 15612412 889917 complement(1476622..1477533) 1 NC_000921.1 similar to H. pylori 26695 gene HP1454; hypothetical protein 1477533 889917 jhp1347 Helicobacter pylori J99 hypothetical protein NP_224065.1 1476622 R 85963 CDS NP_224066.1 15612413 889909 complement(1477543..1477884) 1 NC_000921.1 similar to H. pylori 26695 gene HP1455; hypothetical protein 1477884 889909 jhp1348 Helicobacter pylori J99 hypothetical protein NP_224066.1 1477543 R 85963 CDS NP_224067.1 15612414 889907 complement(1477892..1478419) 1 NC_000921.1 similar to H. pylori 26695 gene HP1456; lipoprotein 1478419 lpp20 889907 lpp20 Helicobacter pylori J99 lipoprotein NP_224067.1 1477892 R 85963 CDS NP_224068.1 15612415 889908 complement(1478443..1479075) 1 NC_000921.1 similar to H. pylori 26695 gene HP1457; hypothetical protein 1479075 889908 jhp1350 Helicobacter pylori J99 hypothetical protein NP_224068.1 1478443 R 85963 CDS NP_224069.1 15612416 889911 complement(1479434..1479748) 1 NC_000921.1 similar to H. pylori 26695 gene HP1458; thioredoxin 1479748 889911 jhp1351 Helicobacter pylori J99 thioredoxin NP_224069.1 1479434 R 85963 CDS NP_224070.1 15612417 889913 complement(1479804..1480592) 1 NC_000921.1 similar to H. pylori 26695 gene HP1459; hypothetical protein 1480592 889913 jhp1352 Helicobacter pylori J99 hypothetical protein NP_224070.1 1479804 R 85963 CDS NP_224071.1 15612418 889910 complement(1480574..1484209) 1 NC_000921.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1484209 dnaE 889910 dnaE Helicobacter pylori J99 DNA polymerase III subunit alpha NP_224071.1 1480574 R 85963 CDS NP_224072.1 15612419 889912 1484358..1485410 1 NC_000921.1 similar to H. pylori 26695 gene HP1461; cytochrome c551 peroxidase 1485410 889912 jhp1354 Helicobacter pylori J99 cytochrome c551 peroxidase NP_224072.1 1484358 D 85963 CDS NP_224073.1 15612420 889914 complement(1485705..1486292) 1 NC_000921.1 similar to H. pylori 26695 gene HP1462; motility protein 1486292 889914 jhp1355 Helicobacter pylori J99 motility protein NP_224073.1 1485705 R 85963 CDS NP_224074.1 15612421 889916 complement(1486311..1486988) 1 NC_000921.1 similar to H. pylori 26695 gene HP1463; hypothetical protein 1486988 889916 jhp1356 Helicobacter pylori J99 hypothetical protein NP_224074.1 1486311 R 85963 CDS NP_224075.1 15612422 889932 complement(1486991..1487806) 1 NC_000921.1 similar to H. pylori 26695 gene HP1464; hypothetical protein 1487806 889932 jhp1357 Helicobacter pylori J99 hypothetical protein NP_224075.1 1486991 R 85963 CDS NP_224076.1 15612423 889506 complement(1487791..1488576) 1 NC_000921.1 similar to H. pylori 26695 gene HP1465; ABC transporter ATP-binding protein 1488576 889506 jhp1358 Helicobacter pylori J99 ABC transporter ATP-binding protein NP_224076.1 1487791 R 85963 CDS NP_224077.1 15612424 889918 complement(1488576..1489709) 1 NC_000921.1 similar to H. pylori 26695 gene HP1466; hypothetical protein 1489709 889918 jhp1359 Helicobacter pylori J99 hypothetical protein NP_224077.1 1488576 R 85963 CDS NP_224078.1 15612425 889920 1489843..1490538 1 NC_000921.1 similar to H. pylori 26695 gene HP1467; hypothetical protein 1490538 889920 jhp1360 Helicobacter pylori J99 hypothetical protein NP_224078.1 1489843 D 85963 CDS NP_224079.1 15612426 889921 complement(1490543..1491565) 1 NC_000921.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1491565 ilvE 889921 ilvE Helicobacter pylori J99 branched-chain amino acid aminotransferase NP_224079.1 1490543 R 85963 CDS NP_224080.1 15612427 889925 complement(1491616..1492362) 1 NC_000921.1 similar to H. pylori 26695 gene HP1469; hypothetical protein 1492362 889925 jhp1362 Helicobacter pylori J99 hypothetical protein NP_224080.1 1491616 R 85963 CDS NP_224081.1 15612428 889922 complement(1492476..1495169) 1 NC_000921.1 similar to H. pylori 26695 gene HP1470; DNA polymerase I 1495169 polA 889922 polA Helicobacter pylori J99 DNA polymerase I NP_224081.1 1492476 R 85963 CDS NP_224082.1 15612429 889923 complement(1495233..1496453) 1 NC_000921.1 similar to H. pylori 26695 gene HP1471; type II restriction enzyme 1496453 889923 jhp1364 Helicobacter pylori J99 type II restriction enzyme NP_224082.1 1495233 R 85963 CDS NP_224083.1 15612430 889924 complement(1496450..1498486) 1 NC_000921.1 similar to H. pylori 26695 gene HP1472; type II DNA modification enzyme 1498486 889924 jhp1365 Helicobacter pylori J99 type II DNA modification enzyme NP_224083.1 1496450 R 85963 CDS NP_224084.1 15612431 889927 complement(1498518..1499093) 1 NC_000921.1 similar to H. pylori 26695 gene HP1473; hypothetical protein 1499093 889927 jhp1366 Helicobacter pylori J99 hypothetical protein NP_224084.1 1498518 R 85963 CDS NP_224085.1 15612432 889509 complement(1499081..1499656) 1 NC_000921.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1499656 tmk 889509 tmk Helicobacter pylori J99 thymidylate kinase NP_224085.1 1499081 R 85963 CDS NP_224086.1 15612433 889926 complement(1499660..1500133) 1 NC_000921.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1500133 coaD 889926 coaD Helicobacter pylori J99 phosphopantetheine adenylyltransferase NP_224086.1 1499660 R 85963 CDS NP_224087.1 15612434 889928 complement(1500133..1500696) 1 NC_000921.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1500696 ubiD 889928 ubiD Helicobacter pylori J99 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_224087.1 1500133 R 85963 CDS NP_224088.1 15612435 889935 complement(1500706..1501362) 1 NC_000921.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1501362 flgA 889935 flgA Helicobacter pylori J99 flagellar basal body P-ring biosynthesis protein FlgA NP_224088.1 1500706 R 85963 CDS NP_224089.1 15612436 889497 complement(1501359..1503404) 1 NC_000921.1 similar to H. pylori 26695 gene HP1478; ATP-dependent DNA helicase 1503404 rep 889497 rep Helicobacter pylori J99 ATP-dependent DNA helicase NP_224089.1 1501359 R 85963 CDS NP_224090.1 15612437 889930 complement(1503404..1505929) 1 NC_000921.1 similar to H. pylori 26695 gene HP1479; hypothetical protein 1505929 889930 jhp1372 Helicobacter pylori J99 hypothetical protein NP_224090.1 1503404 R 85963 CDS NP_224091.1 15612438 889934 complement(1505939..1507186) 1 NC_000921.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1507186 serS 889934 serS Helicobacter pylori J99 seryl-tRNA synthetase NP_224091.1 1505939 R 85963 CDS NP_224092.1 15612439 889503 complement(1507187..1507984) 1 NC_000921.1 similar to H. pylori 26695 gene HP1481; hypothetical protein 1507984 889503 jhp1374 Helicobacter pylori J99 hypothetical protein NP_224092.1 1507187 R 85963 CDS NP_224093.1 15612440 889931 complement(1507988..1508248) 1 NC_000921.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1508248 889931 jhp1375 Helicobacter pylori J99 exodeoxyribonuclease VII small subunit NP_224093.1 1507988 R 85963 CDS NP_224094.1 15612441 889508 complement(1508258..1508998) 1 NC_000921.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1508998 ubiE 889508 ubiE Helicobacter pylori J99 ubiquinone/menaquinone biosynthesis methyltransferase NP_224094.1 1508258 R 85963 CDS NP_224095.1 15612442 889933 complement(1509007..1509453) 1 NC_000921.1 similar to H. pylori 26695 gene HP1484; hypothetical protein 1509453 889933 jhp1377 Helicobacter pylori J99 hypothetical protein NP_224095.1 1509007 R 85963 CDS NP_224096.1 15612443 889504 complement(1509463..1510035) 1 NC_000921.1 similar to H. pylori 26695 gene HP1485; hypothetical protein 1510035 889504 jhp1378 Helicobacter pylori J99 hypothetical protein NP_224096.1 1509463 R 85963 CDS NP_224097.1 15612444 889963 complement(1510022..1511152) 1 NC_000921.1 similar to H. pylori 26695 gene HP1486; hypothetical protein 1511152 889963 jhp1379 Helicobacter pylori J99 hypothetical protein NP_224097.1 1510022 R 85963 CDS NP_224098.1 15612445 889454 complement(1511149..1512246) 1 NC_000921.1 similar to H. pylori 26695 gene HP1487; hypothetical protein 1512246 889454 jhp1380 Helicobacter pylori J99 hypothetical protein NP_224098.1 1511149 R 85963 CDS NP_224099.1 15612446 889936 complement(1512258..1513247) 1 NC_000921.1 similar to H. pylori 26695 gene HP1488; hypothetical protein 1513247 889936 jhp1381 Helicobacter pylori J99 hypothetical protein NP_224099.1 1512258 R 85963 CDS NP_224100.1 15612447 889501 complement(1513259..1514791) 1 NC_000921.1 similar to H. pylori 26695 gene HP1489; lipase-like protein 1514791 889501 jhp1382 Helicobacter pylori J99 lipase-like protein NP_224100.1 1513259 R 85963 CDS NP_224101.1 15612448 889937 complement(1514788..1516113) 1 NC_000921.1 similar to H. pylori 26695 gene HP1490; hypothetical protein 1516113 889937 jhp1383 Helicobacter pylori J99 hypothetical protein NP_224101.1 1514788 R 85963 CDS NP_224102.1 15612449 889498 complement(1516243..1517844) 1 NC_000921.1 similar to H. pylori 26695 gene HP1491; phosphate permease 1517844 889498 jhp1384 Helicobacter pylori J99 phosphate permease NP_224102.1 1516243 R 85963 CDS NP_224103.1 15612450 889941 1517985..1518254 1 NC_000921.1 similar to H. pylori 26695 gene HP1492; NifU-like protein 1518254 889941 jhp1385 Helicobacter pylori J99 NifU-like protein NP_224103.1 1517985 D 85963 CDS NP_224104.1 15612451 889496 1518267..1518878 1 NC_000921.1 similar to H. pylori 26695 gene HP1493; hypothetical protein 1518878 889496 jhp1386 Helicobacter pylori J99 hypothetical protein NP_224104.1 1518267 D 85963 CDS NP_224105.1 15612452 889938 1518882..1520225 1 NC_000921.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1520225 murE 889938 murE Helicobacter pylori J99 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase NP_224105.1 1518882 D 85963 CDS NP_224106.1 15612453 889492 1520228..1521178 1 NC_000921.1 Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1521178 tal 889492 tal Helicobacter pylori J99 transaldolase NP_224106.1 1520228 D 85963 CDS NP_224107.1 15612454 889939 1521233..1521769 1 NC_000921.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1521769 rplY 889939 rplY Helicobacter pylori J99 50S ribosomal protein L25 NP_224107.1 1521233 D 85963 CDS NP_224108.1 15612455 889488 1521779..1522339 1 NC_000921.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1522339 pth 889488 pth Helicobacter pylori J99 peptidyl-tRNA hydrolase NP_224108.1 1521779 D 85963 CDS NP_224109.1 15612456 889940 1522349..1523416 1 NC_000921.1 similar to H. pylori 26695 gene HP1498; hypothetical protein 1523416 889940 jhp1391 Helicobacter pylori J99 hypothetical protein NP_224109.1 1522349 D 85963 CDS NP_224110.1 15612457 889495 1523537..1524457 1 NC_000921.1 similar to H. pylori 26695 gene HP1499; hypothetical protein 1524457 889495 jhp1392 Helicobacter pylori J99 hypothetical protein NP_224110.1 1523537 D 85963 CDS NP_224111.1 15612458 889942 1524624..1524704 1 NC_000921.1 similar to H. pylori 26695 gene HP1500; hypothetical protein 1524704 889942 jhp1393 Helicobacter pylori J99 hypothetical protein NP_224111.1 1524624 D 85963 CDS NP_224112.1 15612459 889491 complement(1524768..1525934) 1 NC_000921.1 similar to H. pylori 26695 gene HP1501; hypothetical protein 1525934 889491 jhp1394 Helicobacter pylori J99 hypothetical protein NP_224112.1 1524768 R 85963 CDS NP_224113.1 15612460 889943 1526113..1526550 1 NC_000921.1 similar to H. pylori 26695 gene HP1502; hypothetical protein 1526550 889943 jhp1395 Helicobacter pylori J99 hypothetical protein NP_224113.1 1526113 D 85963 CDS NP_224114.1 15612461 889482 complement(1526547..1528913) 1 NC_000921.1 similar to H. pylori 26695 gene HP1503; component of cation transport for cbb3-type oxidase 1528913 fixI 889482 fixI Helicobacter pylori J99 component of cation transport for cbb3-type oxidase NP_224114.1 1526547 R 85963 CDS NP_224115.1 15612462 889946 complement(1528923..1529639) 1 NC_000921.1 similar to H. pylori 26695 gene HP1504; hypothetical protein 1529639 889946 jhp1397 Helicobacter pylori J99 hypothetical protein NP_224115.1 1528923 R 85963 CDS NP_224116.1 15612463 889484 complement(1529621..1530655) 1 NC_000921.1 similar to H. pylori 26695 gene HP1505; riboflavin-specific deaminase 1530655 ribD 889484 ribD Helicobacter pylori J99 riboflavin-specific deaminase NP_224116.1 1529621 R 85963 CDS NP_224117.1 15612464 889944 complement(1530659..1531885) 1 NC_000921.1 similar to H. pylori 26695 gene HP1506; sodium/glutamate symporter 1531885 gltS 889944 gltS Helicobacter pylori J99 sodium/glutamate symporter NP_224117.1 1530659 R 85963 CDS NP_224118.1 15612465 889483 1531971..1533170 1 NC_000921.1 similar to H. pylori 26695 gene HP1507; hypothetical protein 1533170 889483 jhp1400 Helicobacter pylori J99 hypothetical protein NP_224118.1 1531971 D 85963 CDS NP_224119.1 15612466 889945 complement(1533180..1534556) 1 NC_000921.1 similar to H. pylori 26695 gene HP1508; ferrodoxin 1534556 889945 jhp1401 Helicobacter pylori J99 ferrodoxin NP_224119.1 1533180 R 85963 CDS NP_224120.1 15612467 889486 1534662..1535324 1 NC_000921.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1535324 889486 jhp1402 Helicobacter pylori J99 glycerol-3-phosphate acyltransferase PlsY NP_224120.1 1534662 D 85963 CDS NP_224121.1 15612468 889949 1535321..1535674 1 NC_000921.1 similar to H. pylori 26695 gene HP1510; dihydroneopterin aldolase 1535674 folB 889949 folB Helicobacter pylori J99 dihydroneopterin aldolase NP_224121.1 1535321 D 85963 CDS NP_224122.1 15612469 889477 1535658..1535984 1 NC_000921.1 similar to H. pylori 26695 gene HP1511; hypothetical protein 1535984 889477 jhp1404 Helicobacter pylori J99 hypothetical protein NP_224122.1 1535658 D 85963 CDS NP_224123.1 15612470 889947 1536153..1538792 1 NC_000921.1 similar to H. pylori 26695 gene HP1512; IRON-regulated outer membrane protein 1538792 frpB_3 889947 frpB_3 Helicobacter pylori J99 IRON-regulated outer membrane protein NP_224123.1 1536153 D 85963 CDS NP_224124.1 15612471 889478 1539018..1540190 1 NC_000921.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1540190 selA 889478 selA Helicobacter pylori J99 selenocysteine synthase NP_224124.1 1539018 D 85963 CDS NP_224125.1 15612472 889948 1540286..1541473 1 NC_000921.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1541473 nusA 889948 nusA Helicobacter pylori J99 transcription elongation factor NusA NP_224125.1 1540286 D 85963 CDS NP_224126.1 15612473 889479 1541530..1542213 1 NC_000921.1 hypothetical protein 1542213 889479 jhp1408 Helicobacter pylori J99 hypothetical protein NP_224126.1 1541530 D 85963 CDS NP_224127.1 15612474 889951 complement(1543496..1547254) 1 NC_000921.1 type II DNA modification enzyme 1547254 889951 jhp1409 Helicobacter pylori J99 type II DNA modification enzyme NP_224127.1 1543496 R 85963 CDS NP_224128.1 15612475 889471 complement(1547376..1550285) 1 NC_000921.1 similar to H. pylori 26695 gene HP1521; type III restriction enzyme 1550285 res_2 889471 res_2 Helicobacter pylori J99 type III restriction enzyme NP_224128.1 1547376 R 85963 CDS NP_224129.1 15612476 889950 complement(join(1550288..1550881,1550883..1552214)) 1 NC_000921.1 similar to TIGR HP1522; expression of this protein is predicted to be regulated by slipped-strand repair at the (G) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; type III DNA modification enzyme 1552214 mod_2 889950 mod_2 Helicobacter pylori J99 type III DNA modification enzyme NP_224129.1 1550288 R 85963 CDS NP_224130.1 15612477 889476 complement(1552266..1554137) 1 NC_000921.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1554137 recG 889476 recG Helicobacter pylori J99 ATP-dependent DNA helicase RecG NP_224130.1 1552266 R 85963 CDS NP_224131.1 15612478 889955 1554214..1554561 1 NC_000921.1 similar to H. pylori 26695 gene HP1524; hypothetical protein 1554561 889955 jhp1413 Helicobacter pylori J99 hypothetical protein NP_224131.1 1554214 D 85963 CDS NP_224132.1 15612479 889468 1554565..1555200 1 NC_000921.1 similar to H. pylori 26695 gene HP1525; hypothetical protein 1555200 889468 jhp1414 Helicobacter pylori J99 hypothetical protein NP_224132.1 1554565 D 85963 CDS NP_224133.1 15612480 889953 complement(1555197..1555949) 1 NC_000921.1 AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III 1555949 exoA 889953 exoA Helicobacter pylori J99 exodeoxyribonuclease III NP_224133.1 1555197 R 85963 CDS NP_224134.1 15612481 889472 complement(1556129..1557568) 1 NC_000921.1 similar to H. pylori 26695 gene HP1527; hypothetical protein 1557568 889472 jhp1416 Helicobacter pylori J99 hypothetical protein NP_224134.1 1556129 R 85963 CDS NP_224135.1 15612482 889952 complement(1557789..1559162) 1 NC_000921.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1559162 dnaA 889952 dnaA Helicobacter pylori J99 chromosome replication initiator DnaA NP_224135.1 1557789 R 85963 CDS NP_224136.1 15612483 889473 1559315..1559857 1 NC_000921.1 similar to H. pylori 26695 gene HP1530; hypothetical protein 1559857 889473 jhp1418 Helicobacter pylori J99 hypothetical protein NP_224136.1 1559315 D 85963 CDS NP_224137.1 15612484 889954 1559902..1560141 1 NC_000921.1 similar to H. pylori 26695 gene HP1531; hypothetical protein 1560141 889954 jhp1419 Helicobacter pylori J99 hypothetical protein NP_224137.1 1559902 D 85963 CDS NP_224138.1 15612485 889462 1560142..1561935 1 NC_000921.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1561935 glmS 889462 glmS Helicobacter pylori J99 glucosamine--fructose-6-phosphate aminotransferase NP_224138.1 1560142 D 85963 CDS NP_224139.1 15612486 889956 1561959..1562585 1 NC_000921.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1562585 thyX 889956 thyX Helicobacter pylori J99 FAD-dependent thymidylate synthase NP_224139.1 1561959 D 85963 CDS NP_224140.1 15612487 889469 complement(1562916..1564790) 1 NC_000921.1 type I restriction enzyme (specificity subunit) 1564790 hsdS_3a 889469 hsdS_3a Helicobacter pylori J99 type I restriction enzyme (specificity subunit) NP_224140.1 1562916 R 85963 CDS NP_224141.1 15612488 889239 complement(1564787..1567234) 1 NC_000921.1 similar to H. pylori 26695 gene HP1403; type I restriction enzyme modification subunit 1567234 hsdM_3 889239 hsdM_3 Helicobacter pylori J99 type I restriction enzyme modification subunit NP_224141.1 1564787 R 85963 CDS NP_224142.1 15612489 889957 1567305..1570280 1 NC_000921.1 similar to H. pylori 26695 gene HP1402; type I restriction enzyme restriction subunit 1570280 hsdR_3 889957 hsdR_3 Helicobacter pylori J99 type I restriction enzyme restriction subunit NP_224142.1 1567305 D 85963 CDS NP_224143.1 15612490 889458 1570280..1570987 1 NC_000921.1 similar to H. pylori 26695 gene HP1401; hypothetical protein 1570987 889458 jhp1425 Helicobacter pylori J99 hypothetical protein NP_224143.1 1570280 D 85963 CDS NP_224144.1 15612491 889958 complement(1571081..1573606) 1 NC_000921.1 similar to H. pylori 26695 gene HP1400; IRON(III) dicitrate transport protein 1573606 fecA_3 889958 fecA_3 Helicobacter pylori J99 IRON(III) dicitrate transport protein NP_224144.1 1571081 R 85963 CDS NP_224145.1 15612492 889313 complement(1574136..1575104) 1 NC_000921.1 similar to H. pylori 26695 gene HP1399; arginase 1575104 rocF 889313 rocF Helicobacter pylori J99 arginase NP_224145.1 1574136 R 85963 CDS NP_224146.1 15612493 889959 1575308..1576450 1 NC_000921.1 similar to H. pylori 26695 gene HP1398; L-alanine dehydrogenase 1576450 ald 889959 ald Helicobacter pylori J99 L-alanine dehydrogenase NP_224146.1 1575308 D 85963 CDS NP_224147.1 15612494 889443 1576698..1577795 1 NC_000921.1 zinc-dependent alcohol dehydrogenase 1577795 889443 jhp1429 Helicobacter pylori J99 zinc-dependent alcohol dehydrogenase NP_224147.1 1576698 D 85963 CDS NP_224148.1 15612495 889960 1577928..1578776 1 NC_000921.1 similar to H. pylori 26695 gene HP1397; hypothetical protein 1578776 889960 jhp1430 Helicobacter pylori J99 hypothetical protein NP_224148.1 1577928 D 85963 CDS NP_224149.1 15612496 889461 1578809..1579690 1 NC_000921.1 similar to H. pylori 26695 gene HP1396; hypothetical protein 1579690 889461 jhp1431 Helicobacter pylori J99 hypothetical protein NP_224149.1 1578809 D 85963 CDS NP_224150.1 15612497 889961 complement(1579701..1580429) 1 NC_000921.1 similar to H. pylori 26695 gene HP1395; hypothetical protein 1580429 889961 jhp1432 Helicobacter pylori J99 hypothetical protein NP_224150.1 1579701 R 85963 CDS NP_224151.1 15612498 889455 1580545..1581468 1 NC_000921.1 similar to H. pylori 26695 gene HP1394; hypothetical protein 1581468 889455 jhp1433 Helicobacter pylori J99 hypothetical protein NP_224151.1 1580545 D 85963 CDS NP_224152.1 15612499 889967 1581506..1583074 1 NC_000921.1 similar to H. pylori 26695 gene HP1393; DNA repair protein(recombination protein N) 1583074 recN 889967 recN Helicobacter pylori J99 DNA repair protein(recombination protein N) NP_224152.1 1581506 D 85963 CDS NP_224153.1 15612500 889448 1583077..1584384 1 NC_000921.1 similar to H. pylori 26695 gene HP1392; fibronectin/fibrinogen-binding protein 1584384 889448 jhp1435 Helicobacter pylori J99 fibronectin/fibrinogen-binding protein NP_224153.1 1583077 D 85963 CDS NP_224154.1 15612501 889964 1584403..1584699 1 NC_000921.1 similar to H. pylori 26695 gene HP1391; hypothetical protein 1584699 889964 jhp1436 Helicobacter pylori J99 hypothetical protein NP_224154.1 1584403 D 85963 CDS NP_224155.1 15612502 889449 1584853..1585623 1 NC_000921.1 hypothetical protein 1585623 889449 jhp1437 Helicobacter pylori J99 hypothetical protein NP_224155.1 1584853 D 85963 CDS NP_224156.1 15612503 889962 complement(1585662..1586633) 1 NC_000921.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1586633 889962 jhp1438 Helicobacter pylori J99 DNA polymerase III subunit epsilon NP_224156.1 1585662 R 85963 CDS NP_224157.1 15612504 889965 complement(1586503..1587156) 1 NC_000921.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1587156 rpe 889965 rpe Helicobacter pylori J99 ribulose-phosphate 3-epimerase NP_224157.1 1586503 R 85963 CDS NP_224158.1 15612505 889456 1587227..1588099 1 NC_000921.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1588099 fbp 889456 fbp Helicobacter pylori J99 fructose-1,6-bisphosphatase NP_224158.1 1587227 D 85963 CDS NP_224159.1 15612506 889972 1588099..1588302 1 NC_000921.1 similar to H. pylori 26695 gene HP1384; hypothetical protein 1588302 889972 jhp1441 Helicobacter pylori J99 hypothetical protein NP_224159.1 1588099 D 85963 CDS NP_224160.1 15612507 889439 join(1588369..1589034,1589036..1589350) 1 NC_000921.1 similar to TIGR HP1366; expression of this protein is predicted to be regulated by slipped-strand repair at the (A) polynucleotide repeat; length of the repeat has been artificially adjusted (removal of one nucleotide) to give the full length protein; type II restriction enzyme 1589350 889439 jhp1442 Helicobacter pylori J99 type II restriction enzyme NP_224160.1 1588369 D 85963 CDS NP_224161.1 15612508 889966 1589437..1590078 1 NC_000921.1 similar to H. pylori 26695 gene HP1365; transcriptional regulator 1590078 889966 jhp1443 Helicobacter pylori J99 transcriptional regulator NP_224161.1 1589437 D 85963 CDS NP_224162.1 15612509 889447 complement(1590257..1591324) 1 NC_000921.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1591324 tsf 889447 tsf Helicobacter pylori J99 elongation factor Ts NP_224162.1 1590257 R 85963 CDS NP_224163.1 15612510 889970 complement(1591324..1592118) 1 NC_000921.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1592118 rpsB 889970 rpsB Helicobacter pylori J99 30S ribosomal protein S2 NP_224163.1 1591324 R 85963 CDS NP_224164.1 15612511 889442 1592367..1595207 1 NC_000921.1 similar to H. pylori 26695 gene HP1553; recombination protein RecB 1595207 pcrA 889442 pcrA Helicobacter pylori J99 recombination protein RecB NP_224164.1 1592367 D 85963 CDS NP_224165.1 15612512 889971 1595231..1596547 1 NC_000921.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1596547 nhaA 889971 nhaA Helicobacter pylori J99 pH-dependent sodium/proton antiporter NP_224165.1 1595231 D 85963 CDS NP_224166.1 15612513 889440 1596595..1596888 1 NC_000921.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1596888 yajC 889440 yajC Helicobacter pylori J99 preprotein translocase subunit YajC NP_224166.1 1596595 D 85963 CDS NP_224167.1 15612514 889286 1596889..1598469 1 NC_000921.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1598469 secD 889286 secD Helicobacter pylori J99 preprotein translocase subunit SecD NP_224167.1 1596889 D 85963 CDS NP_224168.1 15612515 889968 1598478..1599449 1 NC_000921.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1599449 secF 889968 secF Helicobacter pylori J99 preprotein translocase subunit SecF NP_224168.1 1598478 D 85963 CDS NP_224169.1 15612516 889450 1599459..1599797 1 NC_000921.1 similar to H. pylori 26695 gene HP1548; hypothetical protein 1599797 889450 jhp1451 Helicobacter pylori J99 hypothetical protein NP_224169.1 1599459 D 85963 CDS NP_224170.1 15612517 889287 1599807..1602227 1 NC_000921.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1602227 leuS 889287 leuS Helicobacter pylori J99 leucyl-tRNA synthetase NP_224170.1 1599807 D 85963 CDS NP_224171.1 15612518 889976 1602224..1602736 1 NC_000921.1 similar to H. pylori 26695 gene HP1546; hypothetical protein 1602736 889976 jhp1453 Helicobacter pylori J99 hypothetical protein NP_224171.1 1602224 D 85963 CDS NP_224172.1 15612519 889430 1602726..1603895 1 NC_000921.1 similar to H. pylori 26695 gene HP1545; folylpolyglutamate synthase 1603895 folC 889430 folC Helicobacter pylori J99 folylpolyglutamate synthase NP_224172.1 1602726 D 85963 CDS NP_224173.1 15612520 889969 1603895..1604821 1 NC_000921.1 similar to H. pylori 26695 gene HP1544; hypothetical protein 1604821 889969 jhp1455 Helicobacter pylori J99 hypothetical protein NP_224173.1 1603895 D 85963 CDS NP_224174.1 15612521 889444 1604831..1605769 1 NC_000921.1 similar to H. pylori 26695 gene HP1543; hypothetical protein 1605769 889444 jhp1456 Helicobacter pylori J99 hypothetical protein NP_224174.1 1604831 D 85963 CDS NP_224175.1 15612522 889975 1605688..1606098 1 NC_000921.1 similar to H. pylori 26695 gene HP1542; hypothetical protein 1606098 889975 jhp1457 Helicobacter pylori J99 hypothetical protein NP_224175.1 1605688 D 85963 CDS NP_224176.1 15612523 889438 1606102..1609107 1 NC_000921.1 similar to H. pylori 26695 gene HP1541; transcription-repair coupling factor 1609107 mfd 889438 mfd Helicobacter pylori J99 transcription-repair coupling factor NP_224176.1 1606102 D 85963 CDS NP_224177.1 15612524 889978 1609232..1609735 1 NC_000921.1 similar to H. pylori 26695 gene HP1540; ubiquinol cytochrome c oxidoreductase, 2Fe-2S subunit 1609735 petA 889978 petA Helicobacter pylori J99 ubiquinol cytochrome c oxidoreductase, 2Fe-2S subunit NP_224177.1 1609232 D 85963 CDS NP_224178.1 15612525 889433 1609746..1610984 1 NC_000921.1 similar to H. pylori 26695 gene HP1539; ubiquinol cytochrome c oxidoreductase, cytochrome b subunit 1610984 petB 889433 petB Helicobacter pylori J99 ubiquinol cytochrome c oxidoreductase, cytochrome b subunit NP_224178.1 1609746 D 85963 CDS NP_224179.1 15612526 889977 1610981..1611838 1 NC_000921.1 similar to H. pylori 26695 gene HP1538; ubiquinol cytochrome c oxidoreductase, cytochrome c1 1611838 petC 889977 petC Helicobacter pylori J99 ubiquinol cytochrome c oxidoreductase, cytochrome c1 NP_224179.1 1610981 D 85963 CDS NP_224180.1 15612527 889435 complement(1612166..1612696) 1 NC_000921.1 hypothetical protein 1612696 889435 jhp1462 Helicobacter pylori J99 hypothetical protein NP_224180.1 1612166 R 85963 CDS NP_224181.1 15612528 889981 complement(1612696..1613799) 1 NC_000921.1 hypothetical protein 1613799 889981 jhp1463 Helicobacter pylori J99 hypothetical protein NP_224181.1 1612696 R 85963 CDS NP_224182.1 15612529 889973 complement(1614129..1615970) 1 NC_000921.1 similar to H. pylori 26695 gene HP1556; penicillin-binding protein 1615970 889973 jhp1464 Helicobacter pylori J99 penicillin-binding protein NP_224182.1 1614129 R 85963 CDS NP_224183.1 15612530 889299 complement(1616126..1616455) 1 NC_000921.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1616455 fliE 889299 fliE Helicobacter pylori J99 flagellar hook-basal body protein FliE NP_224183.1 1616126 R 85963 CDS NP_224184.1 15612531 889992 complement(1616583..1617068) 1 NC_000921.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1617068 flgC 889992 flgC Helicobacter pylori J99 flagellar basal body rod protein FlgC NP_224184.1 1616583 R 85963 CDS NP_224185.1 15612532 889409 complement(1617081..1617503) 1 NC_000921.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1617503 flgB 889409 flgB Helicobacter pylori J99 flagellar basal-body rod protein FlgB NP_224185.1 1617081 R 85963 CDS NP_224186.1 15612533 889974 1617708..1618874 1 NC_000921.1 similar to H. pylori 26695 gene HP1560; rod shape-determining protein 1618874 rodA_2 889974 rodA_2 Helicobacter pylori J99 rod shape-determining protein NP_224186.1 1617708 D 85963 CDS NP_224187.1 15612534 889441 complement(1618897..1619904) 1 NC_000921.1 similar to H. pylori 26695 gene HP1561; hypothetical protein 1619904 889441 jhp1469 Helicobacter pylori J99 hypothetical protein NP_224187.1 1618897 R 85963 CDS NP_224188.1 15612535 889979 complement(1620112..1621113) 1 NC_000921.1 similar to H. pylori 26695 gene HP1562; hypothetical protein 1621113 889979 jhp1470 Helicobacter pylori J99 hypothetical protein NP_224188.1 1620112 R 85963 CDS NP_224189.1 15612536 889432 1621351..1621947 1 NC_000921.1 similar to H. pylori 26695 gene HP1563; peroxidase 1621947 tsaA 889432 tsaA Helicobacter pylori J99 peroxidase NP_224189.1 1621351 D 85963 CDS NP_224190.1 15612537 889980 1622093..1622908 1 NC_000921.1 similar to H. pylori 26695 gene HP1564; hypothetical protein 1622908 889980 jhp1472 Helicobacter pylori J99 hypothetical protein NP_224190.1 1622093 D 85963 CDS NP_224191.1 15612538 889423 complement(1623355..1625121) 1 NC_000921.1 similar to H. pylori 26695 gene HP1565; penicillin-binding protein 1625121 889423 jhp1473 Helicobacter pylori J99 penicillin-binding protein NP_224191.1 1623355 R 85963 CDS NP_224192.1 15612539 889983 complement(1625102..1625545) 1 NC_000921.1 similar to H. pylori 26695 gene HP1566; hypothetical protein 1625545 889983 jhp1474 Helicobacter pylori J99 hypothetical protein NP_224192.1 1625102 R 85963 CDS NP_224193.1 15612540 889428 complement(1625555..1626181) 1 NC_000921.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1626181 engB 889428 engB Helicobacter pylori J99 ribosome biogenesis GTP-binding protein YsxC NP_224193.1 1625555 R 85963 CDS NP_224194.1 15612541 888969 complement(1626178..1626735) 1 NC_000921.1 similar to H. pylori 26695 gene HP1568; hypothetical protein 1626735 888969 jhp1476 Helicobacter pylori J99 hypothetical protein NP_224194.1 1626178 R 85963 CDS NP_224195.1 15612542 889331 complement(1626735..1627328) 1 NC_000921.1 similar to H. pylori 26695 gene HP1569; hypothetical protein 1627328 889331 jhp1477 Helicobacter pylori J99 hypothetical protein NP_224195.1 1626735 R 85963 CDS NP_224196.1 15612543 889242 complement(1627303..1627797) 1 NC_000921.1 similar to H. pylori 26695 gene HP1570; hypothetical protein 1627797 889242 jhp1478 Helicobacter pylori J99 hypothetical protein NP_224196.1 1627303 R 85963 CDS NP_224197.1 15612544 889303 complement(1627794..1628738) 1 NC_000921.1 similar to H. pylori 26695 gene HP1571; hypothetical protein 1628738 889303 jhp1479 Helicobacter pylori J99 hypothetical protein NP_224197.1 1627794 R 85963 CDS NP_224198.1 15612545 889341 complement(1628738..1629862) 1 NC_000921.1 similar to H. pylori 26695 gene HP1572; regulatory protein DniR 1629862 dniR 889341 dniR Helicobacter pylori J99 regulatory protein DniR NP_224198.1 1628738 R 85963 CDS NP_224199.1 15612546 889362 complement(1629946..1630710) 1 NC_000921.1 similar to H. pylori 26695 gene HP1573; hypothetical protein 1630710 889362 jhp1481 Helicobacter pylori J99 hypothetical protein NP_224199.1 1629946 R 85963 CDS NP_224200.1 15612547 888985 1630785..1631405 1 NC_000921.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1631405 ribC 888985 ribC Helicobacter pylori J99 riboflavin synthase subunit alpha NP_224200.1 1630785 D 85963 CDS NP_224201.1 15612548 889278 1631406..1631678 1 NC_000921.1 similar to H. pylori 26695 gene HP1575; flagellar biosynthesis protein 1631678 flhB_2 889278 flhB_2 Helicobacter pylori J99 flagellar biosynthesis protein NP_224201.1 1631406 D 85963 CDS NP_224202.1 15612549 889222 1631697..1632680 1 NC_000921.1 part of the metNIQ transport system for methionine; methionine ABC transporter ATP-binding protein 1632680 metN 889222 metN Helicobacter pylori J99 methionine ABC transporter ATP-binding protein NP_224202.1 1631697 D 85963 CDS NP_224203.1 15612550 888989 1632682..1633329 1 NC_000921.1 similar to H. pylori 26695 gene HP1577; ABC transporter permease 1633329 888989 jhp1485 Helicobacter pylori J99 ABC transporter permease NP_224203.1 1632682 D 85963 CDS NP_224204.1 15612551 889010 complement(1633520..1633942) 1 NC_000921.1 similar to H. pylori 26695 gene HP1579; hypothetical protein 1633942 889010 jhp1486 Helicobacter pylori J99 hypothetical protein NP_224204.1 1633520 R 85963 CDS NP_224205.1 15612552 889279 complement(1633952..1634548) 1 NC_000921.1 similar to H. pylori 26695 gene HP1580; hypothetical protein 1634548 889279 jhp1487 Helicobacter pylori J99 hypothetical protein NP_224205.1 1633952 R 85963 CDS NP_224206.1 15612553 889007 complement(1634548..1635555) 1 NC_000921.1 similar to H. pylori 26695 gene HP1581; undecaprenyl-phosphate-alpha-N- acetylglucosaminyltransferase 1635555 wecA 889007 wecA Helicobacter pylori J99 undecaprenyl-phosphate-alpha-N- acetylglucosaminyltransferase NP_224206.1 1634548 R 85963 CDS NP_224207.1 15612554 889349 1635691..1636479 1 NC_000921.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1636479 pdxJ 889349 pdxJ Helicobacter pylori J99 pyridoxine 5'-phosphate synthase NP_224207.1 1635691 D 85963 CDS NP_224208.1 15612555 889008 1636481..1637404 1 NC_000921.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1637404 pdxA 889008 pdxA Helicobacter pylori J99 4-hydroxythreonine-4-phosphate dehydrogenase NP_224208.1 1636481 D 85963 CDS NP_224209.1 15612556 889023 1637754..1638776 1 NC_000921.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1638776 ydiE 889023 ydiE Helicobacter pylori J99 DNA-binding/iron metalloprotein/AP endonuclease NP_224209.1 1637754 D 85963 CDS NP_224210.1 15612557 888991 1639654..1640442 1 NC_000921.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1640442 flgG 888991 flgG Helicobacter pylori J99 flagellar basal body rod protein FlgG NP_224210.1 1639654 D 85963 CDS NP_224211.1 15612558 889364 complement(1640766..1641395) 1 NC_000921.1 similar to H. pylori 26695 gene HP1587; hypothetical protein 1641395 889364 jhp1493 Helicobacter pylori J99 hypothetical protein NP_224211.1 1640766 R 85963 CDS NP_224212.1 15612559 889343 complement(1642226..1642987) 1 NC_000921.1 similar to H. pylori 26695 gene HP1588; hypothetical protein 1642987 889343 jhp1494 Helicobacter pylori J99 hypothetical protein NP_224212.1 1642226 R 85963 CDS NP_224213.1 15612560 889347 complement(1643353..1643586) 1 NC_000921.1 hypothetical protein 1643586 889347 jhp1495 Helicobacter pylori J99 hypothetical protein NP_224213.1 1643353 R 85963 CDS