-- dump date   	20140619_112408
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
235279000001	Autotransporter beta-domain; Region: Autotransporter; pfam03797
235279000002	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
235279000003	active site
235279000004	ribulose/triose binding site [chemical binding]; other site
235279000005	phosphate binding site [ion binding]; other site
235279000006	substrate (anthranilate) binding pocket [chemical binding]; other site
235279000007	product (indole) binding pocket [chemical binding]; other site
235279000008	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
235279000009	active site
235279000010	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
235279000011	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
235279000012	putative active site [active]
235279000013	putative metal binding site [ion binding]; other site
235279000014	Hemerythrin; Region: Hemerythrin; cd12107
235279000015	Fe binding site [ion binding]; other site
235279000016	Hemerythrin; Region: Hemerythrin; cd12107
235279000017	Fe binding site [ion binding]; other site
235279000018	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
235279000019	RNA/DNA hybrid binding site [nucleotide binding]; other site
235279000020	active site
235279000021	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279000022	GTPase CgtA; Reviewed; Region: obgE; PRK12299
235279000023	GTP1/OBG; Region: GTP1_OBG; pfam01018
235279000024	Obg GTPase; Region: Obg; cd01898
235279000025	G1 box; other site
235279000026	GTP/Mg2+ binding site [chemical binding]; other site
235279000027	Switch I region; other site
235279000028	G2 box; other site
235279000029	G3 box; other site
235279000030	Switch II region; other site
235279000031	G4 box; other site
235279000032	G5 box; other site
235279000033	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
235279000034	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
235279000035	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
235279000036	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279000037	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
235279000038	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
235279000039	ligand binding site [chemical binding]; other site
235279000040	flexible hinge region; other site
235279000041	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
235279000042	putative switch regulator; other site
235279000043	non-specific DNA interactions [nucleotide binding]; other site
235279000044	DNA binding site [nucleotide binding]
235279000045	sequence specific DNA binding site [nucleotide binding]; other site
235279000046	putative cAMP binding site [chemical binding]; other site
235279000047	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
235279000048	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
235279000049	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
235279000050	hypothetical protein; Provisional; Region: PRK04081
235279000051	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
235279000052	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000053	L-aspartate oxidase; Provisional; Region: PRK06175
235279000054	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
235279000055	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
235279000056	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
235279000057	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
235279000058	GIY-YIG motif/motif A; other site
235279000059	active site
235279000060	catalytic site [active]
235279000061	putative DNA binding site [nucleotide binding]; other site
235279000062	metal binding site [ion binding]; metal-binding site
235279000063	UvrB/uvrC motif; Region: UVR; pfam02151
235279000064	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
235279000065	Actin cytoskeleton-regulatory complex protein END3; Region: End3; pfam12761
235279000066	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
235279000067	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279000068	ATP binding site [chemical binding]; other site
235279000069	G-X-G motif; other site
235279000070	Response regulator receiver domain; Region: Response_reg; pfam00072
235279000071	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279000072	active site
235279000073	phosphorylation site [posttranslational modification]
235279000074	intermolecular recognition site; other site
235279000075	dimerization interface [polypeptide binding]; other site
235279000076	Firmicute plasmid replication protein (RepL); Region: RepL; pfam05732
235279000077	transcription termination factor Rho; Provisional; Region: rho; PRK09376
235279000078	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
235279000079	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
235279000080	RNA binding site [nucleotide binding]; other site
235279000081	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
235279000082	multimer interface [polypeptide binding]; other site
235279000083	Walker A motif; other site
235279000084	ATP binding site [chemical binding]; other site
235279000085	Walker B motif; other site
235279000086	glutamate racemase; Provisional; Region: PRK00865
235279000087	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
235279000088	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
235279000089	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
235279000090	TPP-binding site [chemical binding]; other site
235279000091	dimer interface [polypeptide binding]; other site
235279000092	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
235279000093	PYR/PP interface [polypeptide binding]; other site
235279000094	dimer interface [polypeptide binding]; other site
235279000095	TPP binding site [chemical binding]; other site
235279000096	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
235279000097	phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Region: pheT_bact; TIGR00472
235279000098	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
235279000099	putative tRNA-binding site [nucleotide binding]; other site
235279000100	tRNA synthetase B5 domain; Region: B5; smart00874
235279000101	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
235279000102	dimer interface [polypeptide binding]; other site
235279000103	motif 1; other site
235279000104	motif 3; other site
235279000105	motif 2; other site
235279000106	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
235279000107	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
235279000108	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
235279000109	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
235279000110	dimer interface [polypeptide binding]; other site
235279000111	motif 1; other site
235279000112	active site
235279000113	motif 2; other site
235279000114	motif 3; other site
235279000115	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
235279000116	nucleotide binding site/active site [active]
235279000117	Methyltransferase domain; Region: Methyltransf_31; pfam13847
235279000118	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279000119	S-adenosylmethionine binding site [chemical binding]; other site
235279000120	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
235279000121	putative efflux protein, MATE family; Region: matE; TIGR00797
235279000122	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
235279000123	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
235279000124	G1 box; other site
235279000125	GTP/Mg2+ binding site [chemical binding]; other site
235279000126	Switch I region; other site
235279000127	G2 box; other site
235279000128	G3 box; other site
235279000129	Switch II region; other site
235279000130	G4 box; other site
235279000131	G5 box; other site
235279000132	Nucleoside recognition; Region: Gate; pfam07670
235279000133	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
235279000134	Nucleoside recognition; Region: Gate; pfam07670
235279000135	pantoate--beta-alanine ligase; Region: panC; TIGR00018
235279000136	Pantoate-beta-alanine ligase; Region: PanC; cd00560
235279000137	active site
235279000138	ATP-binding site [chemical binding]; other site
235279000139	pantoate-binding site; other site
235279000140	HXXH motif; other site
235279000141	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
235279000142	active site
235279000143	dimer interface [polypeptide binding]; other site
235279000144	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
235279000145	putative RNA binding site [nucleotide binding]; other site
235279000146	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
235279000147	homopentamer interface [polypeptide binding]; other site
235279000148	active site
235279000149	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
235279000150	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
235279000151	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
235279000152	active site clefts [active]
235279000153	zinc binding site [ion binding]; other site
235279000154	dimer interface [polypeptide binding]; other site
235279000155	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
235279000156	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
235279000157	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
235279000158	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279000159	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279000160	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
235279000161	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
235279000162	tetramer interface [polypeptide binding]; other site
235279000163	heme binding pocket [chemical binding]; other site
235279000164	NADPH binding site [chemical binding]; other site
235279000165	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
235279000166	dimerization interface [polypeptide binding]; other site
235279000167	active site
235279000168	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
235279000169	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
235279000170	dimer interface [polypeptide binding]; other site
235279000171	putative functional site; other site
235279000172	putative MPT binding site; other site
235279000173	ThiS family; Region: ThiS; pfam02597
235279000174	charged pocket; other site
235279000175	hydrophobic patch; other site
235279000176	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
235279000177	MoaE homodimer interface [polypeptide binding]; other site
235279000178	MoaD interaction [polypeptide binding]; other site
235279000179	active site residues [active]
235279000180	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
235279000181	Walker A motif; other site
235279000182	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
235279000183	MPT binding site; other site
235279000184	trimer interface [polypeptide binding]; other site
235279000185	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279000186	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000187	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000188	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
235279000189	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000190	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000191	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000192	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279000193	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
235279000194	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
235279000195	trimer interface [polypeptide binding]; other site
235279000196	dimer interface [polypeptide binding]; other site
235279000197	putative active site [active]
235279000198	Phage shock protein B; Region: PspB; cl05946
235279000199	RmuC family; Region: RmuC; pfam02646
235279000200	putative metal dependent hydrolase; Provisional; Region: PRK11598
235279000201	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
235279000202	Sulfatase; Region: Sulfatase; pfam00884
235279000203	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
235279000204	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
235279000205	catalytic residues [active]
235279000206	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
235279000207	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
235279000208	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
235279000209	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
235279000210	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
235279000211	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
235279000212	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
235279000213	putative substrate-binding site; other site
235279000214	nickel binding site [ion binding]; other site
235279000215	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
235279000216	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
235279000217	homodimer interface [polypeptide binding]; other site
235279000218	substrate-cofactor binding pocket; other site
235279000219	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279000220	catalytic residue [active]
235279000221	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
235279000222	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
235279000223	dimer interface [polypeptide binding]; other site
235279000224	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279000225	catalytic residue [active]
235279000226	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
235279000227	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
235279000228	Domain of unknown function (DUF1792); Region: DUF1792; pfam08759
235279000229	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
235279000230	GDP-Fucose binding site [chemical binding]; other site
235279000231	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
235279000232	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
235279000233	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
235279000234	inhibitor-cofactor binding pocket; inhibition site
235279000235	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279000236	catalytic residue [active]
235279000237	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
235279000238	GDP-Fucose binding site [chemical binding]; other site
235279000239	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
235279000240	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
235279000241	active site
235279000242	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279000243	S-adenosylmethionine binding site [chemical binding]; other site
235279000244	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; pfam01177
235279000245	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279000246	S-adenosylmethionine binding site [chemical binding]; other site
235279000247	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
235279000248	active site
235279000249	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
235279000250	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
235279000251	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
235279000252	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
235279000253	active site
235279000254	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
235279000255	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
235279000256	homodimer interface [polypeptide binding]; other site
235279000257	active site
235279000258	Methyltransferase domain; Region: Methyltransf_23; pfam13489
235279000259	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279000260	S-adenosylmethionine binding site [chemical binding]; other site
235279000261	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
235279000262	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
235279000263	active site
235279000264	motif I; other site
235279000265	motif II; other site
235279000266	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase_4; pfam13669
235279000267	active site
235279000268	Phosphopantetheine attachment site; Region: PP-binding; cl09936
235279000269	Formyltransferase, catalytic core domain; Region: FMT_core; cd08369
235279000270	active site
235279000271	cosubstrate binding site; other site
235279000272	substrate binding site [chemical binding]; other site
235279000273	catalytic site [active]
235279000274	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
235279000275	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
235279000276	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
235279000277	acyl-activating enzyme (AAE) consensus motif; other site
235279000278	acyl-activating enzyme (AAE) consensus motif; other site
235279000279	active site
235279000280	AMP binding site [chemical binding]; other site
235279000281	CoA binding site [chemical binding]; other site
235279000282	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
235279000283	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
235279000284	Adenylate forming domain, Class I; Region: AFD_class_I; cd04433
235279000285	acyl-activating enzyme (AAE) consensus motif; other site
235279000286	acyl-activating enzyme (AAE) consensus motif; other site
235279000287	active site
235279000288	AMP binding site [chemical binding]; other site
235279000289	CoA binding site [chemical binding]; other site
235279000290	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
235279000291	classical (c) SDRs; Region: SDR_c; cd05233
235279000292	NAD(P) binding site [chemical binding]; other site
235279000293	active site
235279000294	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
235279000295	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
235279000296	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
235279000297	putative trimer interface [polypeptide binding]; other site
235279000298	putative active site [active]
235279000299	putative substrate binding site [chemical binding]; other site
235279000300	putative CoA binding site [chemical binding]; other site
235279000301	WxcM-like, C-terminal; Region: FdtA; pfam05523
235279000302	WxcM-like, C-terminal; Region: FdtA; pfam05523
235279000303	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279000304	Radical SAM superfamily; Region: Radical_SAM; pfam04055
235279000305	FeS/SAM binding site; other site
235279000306	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
235279000307	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
235279000308	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
235279000309	NAD binding site [chemical binding]; other site
235279000310	substrate binding site [chemical binding]; other site
235279000311	homodimer interface [polypeptide binding]; other site
235279000312	active site
235279000313	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
235279000314	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
235279000315	substrate binding site; other site
235279000316	tetramer interface; other site
235279000317	GTP-binding protein LepA; Provisional; Region: PRK05433
235279000318	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
235279000319	G1 box; other site
235279000320	putative GEF interaction site [polypeptide binding]; other site
235279000321	GTP/Mg2+ binding site [chemical binding]; other site
235279000322	Switch I region; other site
235279000323	G2 box; other site
235279000324	G3 box; other site
235279000325	Switch II region; other site
235279000326	G4 box; other site
235279000327	G5 box; other site
235279000328	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
235279000329	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
235279000330	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
235279000331	cell division protein FtsW; Region: ftsW; TIGR02614
235279000332	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
235279000333	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
235279000334	active site
235279000335	peptidylprolyl isomerase; Reviewed; Region: prsA; PRK03095
235279000336	SurA N-terminal domain; Region: SurA_N_3; cl07813
235279000337	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
235279000338	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
235279000339	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
235279000340	intersubunit interface [polypeptide binding]; other site
235279000341	active site
235279000342	zinc binding site [ion binding]; other site
235279000343	Na+ binding site [ion binding]; other site
235279000344	elongation factor P; Validated; Region: PRK00529
235279000345	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
235279000346	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
235279000347	RNA binding site [nucleotide binding]; other site
235279000348	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
235279000349	RNA binding site [nucleotide binding]; other site
235279000350	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
235279000351	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279000352	Walker A motif; other site
235279000353	ATP binding site [chemical binding]; other site
235279000354	Walker B motif; other site
235279000355	arginine finger; other site
235279000356	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279000357	Walker A motif; other site
235279000358	ATP binding site [chemical binding]; other site
235279000359	Walker B motif; other site
235279000360	arginine finger; other site
235279000361	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
235279000362	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
235279000363	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
235279000364	trmE is a tRNA modification GTPase; Region: trmE; cd04164
235279000365	G1 box; other site
235279000366	GTP/Mg2+ binding site [chemical binding]; other site
235279000367	Switch I region; other site
235279000368	G2 box; other site
235279000369	Switch II region; other site
235279000370	G3 box; other site
235279000371	G4 box; other site
235279000372	G5 box; other site
235279000373	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
235279000374	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
235279000375	membrane protein insertase; Provisional; Region: PRK01318
235279000376	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
235279000377	Haemolytic domain; Region: Haemolytic; cl00506
235279000378	Ribonuclease P; Region: Ribonuclease_P; pfam00825
235279000379	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
235279000380	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
235279000381	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
235279000382	ligand binding site [chemical binding]; other site
235279000383	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
235279000384	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
235279000385	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
235279000386	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
235279000387	SmpB-tmRNA interface; other site
235279000388	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
235279000389	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
235279000390	carbon storage regulator; Provisional; Region: PRK00568
235279000391	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK04099
235279000392	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
235279000393	RNA binding site [nucleotide binding]; other site
235279000394	active site
235279000395	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279000396	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
235279000397	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279000398	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279000399	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
235279000400	nucleotide binding site/active site [active]
235279000401	HIT family signature motif; other site
235279000402	catalytic residue [active]
235279000403	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
235279000404	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
235279000405	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
235279000406	Acylphosphatase; Region: Acylphosphatase; pfam00708
235279000407	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
235279000408	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
235279000409	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
235279000410	ATP-grasp domain; Region: ATP-grasp_4; cl17255
235279000411	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
235279000412	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
235279000413	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
235279000414	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
235279000415	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
235279000416	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
235279000417	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
235279000418	ligand binding site [chemical binding]; other site
235279000419	NAD binding site [chemical binding]; other site
235279000420	dimerization interface [polypeptide binding]; other site
235279000421	catalytic site [active]
235279000422	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
235279000423	putative L-serine binding site [chemical binding]; other site
235279000424	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
235279000425	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
235279000426	RNA binding site [nucleotide binding]; other site
235279000427	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
235279000428	RNA binding site [nucleotide binding]; other site
235279000429	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
235279000430	RNA binding site [nucleotide binding]; other site
235279000431	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
235279000432	RNA binding site [nucleotide binding]; other site
235279000433	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
235279000434	LytB protein; Region: LYTB; pfam02401
235279000435	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
235279000436	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
235279000437	hinge; other site
235279000438	active site
235279000439	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
235279000440	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
235279000441	dimer interface [polypeptide binding]; other site
235279000442	phosphorylation site [posttranslational modification]
235279000443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279000444	ATP binding site [chemical binding]; other site
235279000445	Mg2+ binding site [ion binding]; other site
235279000446	G-X-G motif; other site
235279000447	flagellar rod assembly protein/muramidase FlgJ; Region: flagell_FlgJ; TIGR02541
235279000448	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
235279000449	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
235279000450	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279000451	Sel1-like repeats; Region: SEL1; smart00671
235279000452	Sel1 repeat; Region: Sel1; cl02723
235279000453	Sel1-like repeats; Region: SEL1; smart00671
235279000454	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279000455	Sel1-like repeats; Region: SEL1; smart00671
235279000456	Sel1-like repeats; Region: SEL1; smart00671
235279000457	Sel1-like repeats; Region: SEL1; smart00671
235279000458	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
235279000459	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
235279000460	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
235279000461	pantothenate kinase; Reviewed; Region: PRK13333
235279000462	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
235279000463	trimer interface [polypeptide binding]; other site
235279000464	active site
235279000465	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
235279000466	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
235279000467	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
235279000468	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
235279000469	Na binding site [ion binding]; other site
235279000470	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
235279000471	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
235279000472	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
235279000473	NAD(P) binding site [chemical binding]; other site
235279000474	catalytic residues [active]
235279000475	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
235279000476	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
235279000477	molybdopterin cofactor binding site; other site
235279000478	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
235279000479	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
235279000480	molybdopterin cofactor binding site; other site
235279000481	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
235279000482	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
235279000483	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
235279000484	4Fe-4S binding domain; Region: Fer4_5; pfam12801
235279000485	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
235279000486	Nitrate reductase cytochrome c-type subunit (NapB); Region: NapB; pfam03892
235279000487	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
235279000488	structural tetrad; other site
235279000489	NapD protein; Region: NapD; cl01163
235279000490	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
235279000491	apolar tunnel; other site
235279000492	heme binding site [chemical binding]; other site
235279000493	dimerization interface [polypeptide binding]; other site
235279000494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
235279000495	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
235279000496	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
235279000497	helix_turn_helix, cAMP Regulatory protein; Region: HTH_CRP; smart00419
235279000498	non-specific DNA interactions [nucleotide binding]; other site
235279000499	DNA binding site [nucleotide binding]
235279000500	sequence specific DNA binding site [nucleotide binding]; other site
235279000501	putative cAMP binding site [chemical binding]; other site
235279000502	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
235279000503	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
235279000504	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
235279000505	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
235279000506	Ligand binding site; other site
235279000507	oligomer interface; other site
235279000508	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
235279000509	HD domain; Region: HD_3; pfam13023
235279000510	Predicted membrane protein [Function unknown]; Region: COG1289
235279000511	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
235279000512	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
235279000513	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
235279000514	NADP-binding site; other site
235279000515	homotetramer interface [polypeptide binding]; other site
235279000516	substrate binding site [chemical binding]; other site
235279000517	homodimer interface [polypeptide binding]; other site
235279000518	active site
235279000519	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
235279000520	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
235279000521	NADP binding site [chemical binding]; other site
235279000522	active site
235279000523	putative substrate binding site [chemical binding]; other site
235279000524	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
235279000525	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
235279000526	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
235279000527	HlyD family secretion protein; Region: HlyD_3; pfam13437
235279000528	S-ribosylhomocysteinase; Provisional; Region: PRK02260
235279000529	Predicted membrane protein [Function unknown]; Region: COG1238
235279000530	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
235279000531	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
235279000532	putative ligand binding site [chemical binding]; other site
235279000533	putative NAD binding site [chemical binding]; other site
235279000534	catalytic site [active]
235279000535	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
235279000536	feedback inhibition sensing region; other site
235279000537	homohexameric interface [polypeptide binding]; other site
235279000538	carbamate kinase; Reviewed; Region: PRK12686
235279000539	nucleotide binding site [chemical binding]; other site
235279000540	N-acetyl-L-glutamate binding site [chemical binding]; other site
235279000541	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
235279000542	flagellar hook protein FlgE, epsilon proteobacterial; Region: flgE_epsilon; TIGR02489
235279000543	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
235279000544	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
235279000545	aromatic chitin/cellulose binding site residues [chemical binding]; other site
235279000546	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
235279000547	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
235279000548	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
235279000549	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
235279000550	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
235279000551	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
235279000552	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39G; cd02423
235279000553	putative active site [active]
235279000554	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
235279000555	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
235279000556	trimer interface [polypeptide binding]; other site
235279000557	active site
235279000558	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
235279000559	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
235279000560	carboxyltransferase (CT) interaction site; other site
235279000561	biotinylation site [posttranslational modification]; other site
235279000562	biotin carboxylase; Validated; Region: PRK08462
235279000563	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
235279000564	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
235279000565	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
235279000566	Flagellin and related hook-associated proteins [Cell motility and secretion]; Region: FlgL; COG1344
235279000567	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
235279000568	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
235279000569	inhibitor-cofactor binding pocket; inhibition site
235279000570	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279000571	catalytic residue [active]
235279000572	Coenzyme F420-reducing hydrogenase, gamma subunit [Energy production and conversion]; Region: FrhG; COG1941
235279000573	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
235279000574	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
235279000575	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
235279000576	gating phenylalanine in ion channel; other site
235279000577	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
235279000578	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
235279000579	UDP-galactopyranose mutase; Region: GLF; pfam03275
235279000580	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
235279000581	active site
235279000582	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
235279000583	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
235279000584	active site
235279000585	Domain of unknown function (DUF4422); Region: DUF4422; pfam14393
235279000586	Domain of unknown function (DUF4422); Region: DUF4422; pfam14393
235279000587	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
235279000588	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
235279000589	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cl00522
235279000590	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
235279000591	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
235279000592	dimerization interface [polypeptide binding]; other site
235279000593	DPS ferroxidase diiron center [ion binding]; other site
235279000594	ion pore; other site
235279000595	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279000596	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279000597	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
235279000598	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
235279000599	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
235279000600	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
235279000601	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
235279000602	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit [Inorganic ion transport and metabolism]; Region: NrfA; COG3303
235279000603	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
235279000604	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
235279000605	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
235279000606	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
235279000607	HlyD family secretion protein; Region: HlyD_3; pfam13437
235279000608	Outer membrane efflux protein; Region: OEP; pfam02321
235279000609	Outer membrane efflux protein; Region: OEP; pfam02321
235279000610	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
235279000611	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
235279000612	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
235279000613	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
235279000614	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
235279000615	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
235279000616	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
235279000617	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
235279000618	molybdopterin cofactor binding site; other site
235279000619	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
235279000620	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
235279000621	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
235279000622	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
235279000623	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
235279000624	Restriction endonuclease EcoRV; Region: Endonuc-EcoRV; pfam09233
235279000625	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
235279000626	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
235279000627	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
235279000628	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
235279000629	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
235279000630	type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359
235279000631	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
235279000632	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
235279000633	type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355
235279000634	Protein of unknown function (DUF877); Region: DUF877; pfam05943
235279000635	type VI secretion protein, VC_A0107 family; Region: VI_chp_5; TIGR03358
235279000636	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
235279000637	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
235279000638	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
235279000639	type IV / VI secretion system protein, DotU family; Region: IV_VI_DotU; TIGR03349
235279000640	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
235279000641	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
235279000642	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
235279000643	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
235279000644	phosphopeptide binding site; other site
235279000645	Conserved oligomeric complex COG6; Region: COG6; pfam06419
235279000646	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
235279000647	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
235279000648	active site
235279000649	DNA binding site [nucleotide binding]
235279000650	Int/Topo IB signature motif; other site
235279000651	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
235279000652	putative active site [active]
235279000653	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
235279000654	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
235279000655	anti sigma factor interaction site; other site
235279000656	regulatory phosphorylation site [posttranslational modification]; other site
235279000657	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
235279000658	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
235279000659	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279000660	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
235279000661	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
235279000662	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
235279000663	AIR synthase related protein, N-terminal domain; Region: AIRS; pfam00586
235279000664	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
235279000665	Glutamine amidotransferase class-I; Region: GATase; pfam00117
235279000666	glutamine binding [chemical binding]; other site
235279000667	catalytic triad [active]
235279000668	aminodeoxychorismate synthase; Provisional; Region: PRK07508
235279000669	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
235279000670	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
235279000671	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
235279000672	homodimer interface [polypeptide binding]; other site
235279000673	substrate-cofactor binding pocket; other site
235279000674	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279000675	catalytic residue [active]
235279000676	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279000677	2-acyl-glycerophospho-ethanolamine acyltransferase; Validated; Region: PRK08633
235279000678	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
235279000679	putative acyl-acceptor binding pocket; other site
235279000680	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
235279000681	acyl-activating enzyme (AAE) consensus motif; other site
235279000682	putative AMP binding site [chemical binding]; other site
235279000683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
235279000684	GTPase Era; Reviewed; Region: era; PRK00089
235279000685	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
235279000686	G1 box; other site
235279000687	GTP/Mg2+ binding site [chemical binding]; other site
235279000688	Switch I region; other site
235279000689	G2 box; other site
235279000690	Switch II region; other site
235279000691	G3 box; other site
235279000692	G4 box; other site
235279000693	G5 box; other site
235279000694	KH domain; Region: KH_2; pfam07650
235279000695	G-X-X-G motif; other site
235279000696	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
235279000697	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279000698	Walker A motif; other site
235279000699	ATP binding site [chemical binding]; other site
235279000700	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
235279000701	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
235279000702	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
235279000703	active site
235279000704	HslU subunit interaction site [polypeptide binding]; other site
235279000705	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
235279000706	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
235279000707	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
235279000708	Protein of unknown function DUF45; Region: DUF45; pfam01863
235279000709	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK14607
235279000710	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
235279000711	glutamine binding [chemical binding]; other site
235279000712	catalytic triad [active]
235279000713	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
235279000714	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
235279000715	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
235279000716	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
235279000717	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
235279000718	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
235279000719	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
235279000720	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
235279000721	DEAD/DEAH box helicase; Region: DEAD; pfam00270
235279000722	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
235279000723	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
235279000724	nucleotide binding region [chemical binding]; other site
235279000725	ATP-binding site [chemical binding]; other site
235279000726	SEC-C motif; Region: SEC-C; pfam02810
235279000727	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
235279000728	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
235279000729	FtsX-like permease family; Region: FtsX; pfam02687
235279000730	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
235279000731	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
235279000732	dimerization interface [polypeptide binding]; other site
235279000733	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
235279000734	ATP binding site [chemical binding]; other site
235279000735	AAA domain; Region: AAA_11; pfam13086
235279000736	Part of AAA domain; Region: AAA_19; pfam13245
235279000737	AAA domain; Region: AAA_12; pfam13087
235279000738	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
235279000739	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
235279000740	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
235279000741	HupF/HypC family; Region: HupF_HypC; pfam01455
235279000742	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
235279000743	Acylphosphatase; Region: Acylphosphatase; pfam00708
235279000744	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
235279000745	HypF finger; Region: zf-HYPF; pfam07503
235279000746	HypF finger; Region: zf-HYPF; pfam07503
235279000747	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
235279000748	Phosphoglycerate kinase; Region: PGK; pfam00162
235279000749	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
235279000750	substrate binding site [chemical binding]; other site
235279000751	hinge regions; other site
235279000752	ADP binding site [chemical binding]; other site
235279000753	catalytic site [active]
235279000754	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
235279000755	dinuclear metal binding motif [ion binding]; other site
235279000756	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
235279000757	S-adenosylmethionine binding site [chemical binding]; other site
235279000758	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
235279000759	tetramerization interface [polypeptide binding]; other site
235279000760	active site
235279000761	hypothetical protein; Provisional; Region: PRK03762
235279000762	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
235279000763	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
235279000764	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
235279000765	substrate binding pocket [chemical binding]; other site
235279000766	chain length determination region; other site
235279000767	substrate-Mg2+ binding site; other site
235279000768	catalytic residues [active]
235279000769	aspartate-rich region 1; other site
235279000770	active site lid residues [active]
235279000771	aspartate-rich region 2; other site
235279000772	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
235279000773	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
235279000774	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
235279000775	putative ATP binding site [chemical binding]; other site
235279000776	putative substrate interface [chemical binding]; other site
235279000777	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
235279000778	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
235279000779	putative active site; other site
235279000780	catalytic triad [active]
235279000781	putative dimer interface [polypeptide binding]; other site
235279000782	Protein of unknown function (DUF3015); Region: DUF3015; pfam11220
235279000783	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
235279000784	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
235279000785	putative active site [active]
235279000786	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279000787	dimer interface [polypeptide binding]; other site
235279000788	conserved gate region; other site
235279000789	putative PBP binding loops; other site
235279000790	ABC-ATPase subunit interface; other site
235279000791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279000792	dimer interface [polypeptide binding]; other site
235279000793	conserved gate region; other site
235279000794	putative PBP binding loops; other site
235279000795	ABC-ATPase subunit interface; other site
235279000796	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
235279000797	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
235279000798	Walker A/P-loop; other site
235279000799	ATP binding site [chemical binding]; other site
235279000800	Q-loop/lid; other site
235279000801	ABC transporter signature motif; other site
235279000802	Walker B; other site
235279000803	D-loop; other site
235279000804	H-loop/switch region; other site
235279000805	DinB family; Region: DinB; cl17821
235279000806	salicylate synthase MbtI; Reviewed; Region: PRK07912
235279000807	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
235279000808	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
235279000809	active site
235279000810	(T/H)XGH motif; other site
235279000811	nickel responsive regulator; Provisional; Region: PRK00630
235279000812	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
235279000813	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
235279000814	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
235279000815	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
235279000816	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
235279000817	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
235279000818	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
235279000819	Cytochrome c; Region: Cytochrom_C; cl11414
235279000820	elongation factor G; Reviewed; Region: PRK00007
235279000821	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
235279000822	G1 box; other site
235279000823	putative GEF interaction site [polypeptide binding]; other site
235279000824	GTP/Mg2+ binding site [chemical binding]; other site
235279000825	Switch I region; other site
235279000826	G2 box; other site
235279000827	G3 box; other site
235279000828	Switch II region; other site
235279000829	G4 box; other site
235279000830	G5 box; other site
235279000831	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
235279000832	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
235279000833	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
235279000834	30S ribosomal protein S7; Validated; Region: PRK05302
235279000835	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
235279000836	S17 interaction site [polypeptide binding]; other site
235279000837	S8 interaction site; other site
235279000838	16S rRNA interaction site [nucleotide binding]; other site
235279000839	streptomycin interaction site [chemical binding]; other site
235279000840	23S rRNA interaction site [nucleotide binding]; other site
235279000841	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
235279000842	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
235279000843	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
235279000844	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
235279000845	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
235279000846	RPB11 interaction site [polypeptide binding]; other site
235279000847	RPB12 interaction site [polypeptide binding]; other site
235279000848	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
235279000849	RPB3 interaction site [polypeptide binding]; other site
235279000850	RPB1 interaction site [polypeptide binding]; other site
235279000851	RPB11 interaction site [polypeptide binding]; other site
235279000852	RPB10 interaction site [polypeptide binding]; other site
235279000853	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
235279000854	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
235279000855	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
235279000856	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
235279000857	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
235279000858	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
235279000859	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
235279000860	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
235279000861	DNA binding site [nucleotide binding]
235279000862	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
235279000863	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
235279000864	core dimer interface [polypeptide binding]; other site
235279000865	peripheral dimer interface [polypeptide binding]; other site
235279000866	L10 interface [polypeptide binding]; other site
235279000867	L11 interface [polypeptide binding]; other site
235279000868	putative EF-Tu interaction site [polypeptide binding]; other site
235279000869	putative EF-G interaction site [polypeptide binding]; other site
235279000870	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
235279000871	23S rRNA interface [nucleotide binding]; other site
235279000872	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
235279000873	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
235279000874	mRNA/rRNA interface [nucleotide binding]; other site
235279000875	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
235279000876	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
235279000877	23S rRNA interface [nucleotide binding]; other site
235279000878	L7/L12 interface [polypeptide binding]; other site
235279000879	putative thiostrepton binding site; other site
235279000880	L25 interface [polypeptide binding]; other site
235279000881	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
235279000882	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
235279000883	putative homodimer interface [polypeptide binding]; other site
235279000884	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
235279000885	heterodimer interface [polypeptide binding]; other site
235279000886	homodimer interface [polypeptide binding]; other site
235279000887	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
235279000888	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
235279000889	elongation factor Tu; Reviewed; Region: PRK00049
235279000890	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
235279000891	G1 box; other site
235279000892	GEF interaction site [polypeptide binding]; other site
235279000893	GTP/Mg2+ binding site [chemical binding]; other site
235279000894	Switch I region; other site
235279000895	G2 box; other site
235279000896	G3 box; other site
235279000897	Switch II region; other site
235279000898	G4 box; other site
235279000899	G5 box; other site
235279000900	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
235279000901	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
235279000902	Antibiotic Binding Site [chemical binding]; other site
235279000903	septation ring formation regulator EzrA; Provisional; Region: PRK04778
235279000904	hypothetical protein; Provisional; Region: PRK05839
235279000905	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
235279000906	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279000907	homodimer interface [polypeptide binding]; other site
235279000908	catalytic residue [active]
235279000909	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
235279000910	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
235279000911	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
235279000912	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
235279000913	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
235279000914	MutS domain III; Region: MutS_III; cl17822
235279000915	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279000916	Walker A/P-loop; other site
235279000917	ATP binding site [chemical binding]; other site
235279000918	Q-loop/lid; other site
235279000919	ABC transporter signature motif; other site
235279000920	Walker B; other site
235279000921	D-loop; other site
235279000922	H-loop/switch region; other site
235279000923	Smr domain; Region: Smr; pfam01713
235279000924	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
235279000925	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
235279000926	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
235279000927	Anaerobic c4-dicarboxylate membrane transporter; Region: DcuA_DcuB; cl01040
235279000928	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
235279000929	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
235279000930	NAD(P) binding site [chemical binding]; other site
235279000931	active site
235279000932	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
235279000933	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
235279000934	nucleophilic elbow; other site
235279000935	catalytic triad; other site
235279000936	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
235279000937	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
235279000938	acyl-activating enzyme (AAE) consensus motif; other site
235279000939	putative AMP binding site [chemical binding]; other site
235279000940	putative active site [active]
235279000941	putative CoA binding site [chemical binding]; other site
235279000942	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
235279000943	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
235279000944	tetramer interface [polypeptide binding]; other site
235279000945	active site
235279000946	Mg2+/Mn2+ binding site [ion binding]; other site
235279000947	Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS) catalyzes...; Region: Ec2MCS_like; cd06108
235279000948	dimer interface [polypeptide binding]; other site
235279000949	Citrate synthase; Region: Citrate_synt; pfam00285
235279000950	active site
235279000951	citrylCoA binding site [chemical binding]; other site
235279000952	oxalacetate/citrate binding site [chemical binding]; other site
235279000953	coenzyme A binding site [chemical binding]; other site
235279000954	catalytic triad [active]
235279000955	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
235279000956	2-methylcitrate dehydratase; Region: prpD; TIGR02330
235279000957	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
235279000958	urease subunit alpha; Provisional; Region: PRK13986
235279000959	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
235279000960	alpha-gamma subunit interface [polypeptide binding]; other site
235279000961	beta-gamma subunit interface [polypeptide binding]; other site
235279000962	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
235279000963	gamma-beta subunit interface [polypeptide binding]; other site
235279000964	alpha-beta subunit interface [polypeptide binding]; other site
235279000965	urease subunit alpha; Reviewed; Region: ureC; PRK13207
235279000966	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
235279000967	subunit interactions [polypeptide binding]; other site
235279000968	active site
235279000969	flap region; other site
235279000970	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
235279000971	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
235279000972	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
235279000973	dimer interface [polypeptide binding]; other site
235279000974	catalytic residues [active]
235279000975	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
235279000976	UreF; Region: UreF; pfam01730
235279000977	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
235279000978	UreD urease accessory protein; Region: UreD; pfam01774
235279000979	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
235279000980	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
235279000981	Walker A/P-loop; other site
235279000982	ATP binding site [chemical binding]; other site
235279000983	Q-loop/lid; other site
235279000984	ABC transporter signature motif; other site
235279000985	Walker B; other site
235279000986	D-loop; other site
235279000987	H-loop/switch region; other site
235279000988	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
235279000989	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279000990	dimer interface [polypeptide binding]; other site
235279000991	conserved gate region; other site
235279000992	putative PBP binding loops; other site
235279000993	ABC-ATPase subunit interface; other site
235279000994	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
235279000995	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
235279000996	Walker A/P-loop; other site
235279000997	ATP binding site [chemical binding]; other site
235279000998	Q-loop/lid; other site
235279000999	ABC transporter signature motif; other site
235279001000	Walker B; other site
235279001001	D-loop; other site
235279001002	H-loop/switch region; other site
235279001003	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279001004	dimer interface [polypeptide binding]; other site
235279001005	conserved gate region; other site
235279001006	putative PBP binding loops; other site
235279001007	ABC-ATPase subunit interface; other site
235279001008	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
235279001009	substrate binding site [chemical binding]; other site
235279001010	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
235279001011	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
235279001012	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
235279001013	N-terminal plug; other site
235279001014	ligand-binding site [chemical binding]; other site
235279001015	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
235279001016	nucleotide binding site [chemical binding]; other site
235279001017	homotetrameric interface [polypeptide binding]; other site
235279001018	putative phosphate binding site [ion binding]; other site
235279001019	putative allosteric binding site; other site
235279001020	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
235279001021	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
235279001022	putative active site [active]
235279001023	substrate binding site [chemical binding]; other site
235279001024	putative cosubstrate binding site; other site
235279001025	catalytic site [active]
235279001026	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
235279001027	substrate binding site [chemical binding]; other site
235279001028	biotin--protein ligase; Provisional; Region: PRK08477
235279001029	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
235279001030	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
235279001031	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
235279001032	P-loop; other site
235279001033	Magnesium ion binding site [ion binding]; other site
235279001034	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
235279001035	Magnesium ion binding site [ion binding]; other site
235279001036	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
235279001037	ParB-like nuclease domain; Region: ParBc; pfam02195
235279001038	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
235279001039	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
235279001040	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
235279001041	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
235279001042	F0F1 ATP synthase subunit delta; Validated; Region: PRK08474
235279001043	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
235279001044	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
235279001045	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
235279001046	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
235279001047	beta subunit interaction interface [polypeptide binding]; other site
235279001048	Walker A motif; other site
235279001049	ATP binding site [chemical binding]; other site
235279001050	Walker B motif; other site
235279001051	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
235279001052	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
235279001053	core domain interface [polypeptide binding]; other site
235279001054	delta subunit interface [polypeptide binding]; other site
235279001055	epsilon subunit interface [polypeptide binding]; other site
235279001056	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
235279001057	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
235279001058	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
235279001059	alpha subunit interaction interface [polypeptide binding]; other site
235279001060	Walker A motif; other site
235279001061	ATP binding site [chemical binding]; other site
235279001062	Walker B motif; other site
235279001063	inhibitor binding site; inhibition site
235279001064	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
235279001065	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK01474
235279001066	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
235279001067	gamma subunit interface [polypeptide binding]; other site
235279001068	epsilon subunit interface [polypeptide binding]; other site
235279001069	LBP interface [polypeptide binding]; other site
235279001070	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
235279001071	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
235279001072	TolR protein; Region: tolR; TIGR02801
235279001073	TonB C terminal; Region: TonB_2; pfam13103
235279001074	translocation protein TolB; Provisional; Region: tolB; PRK04043
235279001075	TolB amino-terminal domain; Region: TolB_N; pfam04052
235279001076	putative outer membrane lipoprotein; Provisional; Region: PRK09967
235279001077	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
235279001078	ligand binding site [chemical binding]; other site
235279001079	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
235279001080	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
235279001081	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
235279001082	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
235279001083	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
235279001084	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
235279001085	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
235279001086	ribosome recycling factor; Reviewed; Region: frr; PRK00083
235279001087	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
235279001088	hinge region; other site
235279001089	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
235279001090	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
235279001091	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
235279001092	active site
235279001093	dimer interface [polypeptide binding]; other site
235279001094	motif 1; other site
235279001095	motif 2; other site
235279001096	motif 3; other site
235279001097	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
235279001098	anticodon binding site; other site
235279001099	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
235279001100	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
235279001101	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
235279001102	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
235279001103	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
235279001104	23S rRNA binding site [nucleotide binding]; other site
235279001105	L21 binding site [polypeptide binding]; other site
235279001106	L13 binding site [polypeptide binding]; other site
235279001107	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
235279001108	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
235279001109	putative active site [active]
235279001110	putative metal binding site [ion binding]; other site
235279001111	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
235279001112	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
235279001113	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
235279001114	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
235279001115	metal binding site [ion binding]; metal-binding site
235279001116	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
235279001117	SPFH domain / Band 7 family; Region: Band_7; pfam01145
235279001118	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
235279001119	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
235279001120	homodimer interface [polypeptide binding]; other site
235279001121	substrate-cofactor binding pocket; other site
235279001122	catalytic residue [active]
235279001123	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
235279001124	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
235279001125	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
235279001126	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
235279001127	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
235279001128	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
235279001129	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
235279001130	protein binding site [polypeptide binding]; other site
235279001131	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
235279001132	protein binding site [polypeptide binding]; other site
235279001133	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
235279001134	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
235279001135	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
235279001136	CheB methylesterase; Region: CheB_methylest; pfam01339
235279001137	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
235279001138	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
235279001139	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279001140	ATP binding site [chemical binding]; other site
235279001141	putative Mg++ binding site [ion binding]; other site
235279001142	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
235279001143	nucleotide binding region [chemical binding]; other site
235279001144	ATP-binding site [chemical binding]; other site
235279001145	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
235279001146	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
235279001147	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
235279001148	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279001149	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
235279001150	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279001151	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
235279001152	Lipopolysaccharide-assembly; Region: LptE; pfam04390
235279001153	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
235279001154	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
235279001155	HIGH motif; other site
235279001156	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
235279001157	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
235279001158	active site
235279001159	KMSKS motif; other site
235279001160	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
235279001161	tRNA binding surface [nucleotide binding]; other site
235279001162	alanine racemase; Reviewed; Region: PRK13340
235279001163	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme, Alanine Racemase 2; Region: PLPDE_III_AR2; cd06826
235279001164	active site
235279001165	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
235279001166	dimer interface [polypeptide binding]; other site
235279001167	substrate binding site [chemical binding]; other site
235279001168	catalytic residues [active]
235279001169	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
235279001170	FHIPEP family; Region: FHIPEP; pfam00771
235279001171	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
235279001172	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
235279001173	active site
235279001174	cosubstrate binding site; other site
235279001175	substrate binding site [chemical binding]; other site
235279001176	catalytic site [active]
235279001177	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
235279001178	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
235279001179	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
235279001180	Na2 binding site [ion binding]; other site
235279001181	putative substrate binding site 1 [chemical binding]; other site
235279001182	Na binding site 1 [ion binding]; other site
235279001183	putative substrate binding site 2 [chemical binding]; other site
235279001184	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
235279001185	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
235279001186	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
235279001187	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279001188	Walker A motif; other site
235279001189	ATP binding site [chemical binding]; other site
235279001190	Walker B motif; other site
235279001191	arginine finger; other site
235279001192	Predicted ATPases [General function prediction only]; Region: COG1106
235279001193	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279001194	Walker A/P-loop; other site
235279001195	ATP binding site [chemical binding]; other site
235279001196	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279001197	Walker B; other site
235279001198	D-loop; other site
235279001199	H-loop/switch region; other site
235279001200	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279001201	dimer interface [polypeptide binding]; other site
235279001202	putative CheW interface [polypeptide binding]; other site
235279001203	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
235279001204	AAA domain; Region: AAA_14; pfam13173
235279001205	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
235279001206	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
235279001207	purine monophosphate binding site [chemical binding]; other site
235279001208	dimer interface [polypeptide binding]; other site
235279001209	putative catalytic residues [active]
235279001210	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
235279001211	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
235279001212	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
235279001213	active site
235279001214	catalytic site [active]
235279001215	substrate binding site [chemical binding]; other site
235279001216	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
235279001217	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
235279001218	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
235279001219	putative active site [active]
235279001220	oxyanion strand; other site
235279001221	catalytic triad [active]
235279001222	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
235279001223	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
235279001224	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
235279001225	dihydrodipicolinate reductase; Provisional; Region: PRK00048
235279001226	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
235279001227	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
235279001228	amidophosphoribosyltransferase; Provisional; Region: PRK08525
235279001229	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
235279001230	active site
235279001231	tetramer interface [polypeptide binding]; other site
235279001232	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
235279001233	active site
235279001234	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
235279001235	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
235279001236	glucose-6-phosphate isomerase; Provisional; Region: PRK03868
235279001237	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
235279001238	dimer interface [polypeptide binding]; other site
235279001239	active site
235279001240	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
235279001241	dimer interface [polypeptide binding]; other site
235279001242	active site
235279001243	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
235279001244	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
235279001245	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
235279001246	Phage protein Gp37/Gp68; Region: Gp37_Gp68; cl15384
235279001247	polyphosphate kinase; Provisional; Region: PRK05443
235279001248	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
235279001249	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
235279001250	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
235279001251	putative domain interface [polypeptide binding]; other site
235279001252	putative active site [active]
235279001253	catalytic site [active]
235279001254	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
235279001255	putative domain interface [polypeptide binding]; other site
235279001256	putative active site [active]
235279001257	catalytic site [active]
235279001258	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
235279001259	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
235279001260	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
235279001261	23S rRNA interface [nucleotide binding]; other site
235279001262	L3 interface [polypeptide binding]; other site
235279001263	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
235279001264	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
235279001265	flagellar motor protein MotA; Validated; Region: PRK08456
235279001266	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
235279001267	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
235279001268	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
235279001269	ligand binding site [chemical binding]; other site
235279001270	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
235279001271	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279001272	Walker A motif; other site
235279001273	ATP binding site [chemical binding]; other site
235279001274	Walker B motif; other site
235279001275	arginine finger; other site
235279001276	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
235279001277	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
235279001278	oligomerization interface [polypeptide binding]; other site
235279001279	active site
235279001280	metal binding site [ion binding]; metal-binding site
235279001281	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
235279001282	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
235279001283	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
235279001284	Protein of unknown function (DUF3365); Region: DUF3365; pfam11845
235279001285	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
235279001286	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
235279001287	dimerization interface [polypeptide binding]; other site
235279001288	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279001289	dimer interface [polypeptide binding]; other site
235279001290	putative CheW interface [polypeptide binding]; other site
235279001291	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
235279001292	RuvA N terminal domain; Region: RuvA_N; pfam01330
235279001293	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
235279001294	Protein of unknown function (DUF342); Region: DUF342; pfam03961
235279001295	MviN-like protein; Region: MVIN; pfam03023
235279001296	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
235279001297	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
235279001298	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
235279001299	active site
235279001300	HIGH motif; other site
235279001301	nucleotide binding site [chemical binding]; other site
235279001302	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
235279001303	KMSKS motif; other site
235279001304	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
235279001305	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
235279001306	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
235279001307	active site
235279001308	nucleotide binding site [chemical binding]; other site
235279001309	HIGH motif; other site
235279001310	KMSKS motif; other site
235279001311	Riboflavin kinase; Region: Flavokinase; pfam01687
235279001312	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
235279001313	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
235279001314	RNA binding surface [nucleotide binding]; other site
235279001315	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279001316	S-adenosylmethionine binding site [chemical binding]; other site
235279001317	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
235279001318	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
235279001319	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
235279001320	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
235279001321	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
235279001322	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
235279001323	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
235279001324	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
235279001325	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
235279001326	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
235279001327	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279001328	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
235279001329	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
235279001330	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279001331	catalytic residue [active]
235279001332	AIR carboxylase; Region: AIRC; smart01001
235279001333	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
235279001334	Protein of unknown function DUF89; Region: DUF89; pfam01937
235279001335	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
235279001336	dimer interface [polypeptide binding]; other site
235279001337	motif 1; other site
235279001338	active site
235279001339	motif 2; other site
235279001340	motif 3; other site
235279001341	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
235279001342	active site
235279001343	Zn binding site [ion binding]; other site
235279001344	Bacterial SH3 domain; Region: SH3_3; pfam08239
235279001345	Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390
235279001346	putative active site [active]
235279001347	putative metal binding site [ion binding]; other site
235279001348	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
235279001349	Exoribonuclease R [Transcription]; Region: VacB; COG0557
235279001350	RNB domain; Region: RNB; pfam00773
235279001351	DNA polymerase III subunit delta; Validated; Region: PRK08487
235279001352	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
235279001353	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
235279001354	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
235279001355	dimer interface [polypeptide binding]; other site
235279001356	ssDNA binding site [nucleotide binding]; other site
235279001357	tetramer (dimer of dimers) interface [polypeptide binding]; other site
235279001358	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
235279001359	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
235279001360	Caenorhabditis protein of unknown function, DUF268; Region: DUF268; pfam03269
235279001361	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
235279001362	16S/18S rRNA binding site [nucleotide binding]; other site
235279001363	S13e-L30e interaction site [polypeptide binding]; other site
235279001364	25S rRNA binding site [nucleotide binding]; other site
235279001365	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
235279001366	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
235279001367	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
235279001368	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
235279001369	DNA binding residues [nucleotide binding]
235279001370	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
235279001371	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
235279001372	TPP-binding site [chemical binding]; other site
235279001373	putative dimer interface [polypeptide binding]; other site
235279001374	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
235279001375	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
235279001376	dimer interface [polypeptide binding]; other site
235279001377	PYR/PP interface [polypeptide binding]; other site
235279001378	TPP binding site [chemical binding]; other site
235279001379	substrate binding site [chemical binding]; other site
235279001380	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
235279001381	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
235279001382	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
235279001383	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
235279001384	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
235279001385	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
235279001386	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
235279001387	active site
235279001388	HIGH motif; other site
235279001389	dimer interface [polypeptide binding]; other site
235279001390	KMSKS motif; other site
235279001391	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279001392	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279001393	glutamine synthetase, type I; Region: GlnA; TIGR00653
235279001394	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
235279001395	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
235279001396	CoA binding domain; Region: CoA_binding; cl17356
235279001397	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
235279001398	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
235279001399	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
235279001400	trimerization site [polypeptide binding]; other site
235279001401	active site
235279001402	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
235279001403	NifU-like domain; Region: NifU; cl00484
235279001404	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
235279001405	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
235279001406	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
235279001407	catalytic residue [active]
235279001408	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
235279001409	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
235279001410	Walker A motif/ATP binding site; other site
235279001411	Walker B motif; other site
235279001412	trigger factor; Provisional; Region: tig; PRK01490
235279001413	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
235279001414	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
235279001415	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
235279001416	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
235279001417	oligomer interface [polypeptide binding]; other site
235279001418	active site residues [active]
235279001419	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
235279001420	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
235279001421	I-site; other site
235279001422	active site
235279001423	metal binding site [ion binding]; metal-binding site
235279001424	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
235279001425	active site
235279001426	catalytic residues [active]
235279001427	metal binding site [ion binding]; metal-binding site
235279001428	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
235279001429	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
235279001430	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
235279001431	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
235279001432	Uncharacterized family 3; belongs to a superfamily containing the transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156; Region: CsoR-like_DUF156_3; cd10160
235279001433	putative homodimer interface [polypeptide binding]; other site
235279001434	putative homotetramer interface [polypeptide binding]; other site
235279001435	putative metal binding site [ion binding]; other site
235279001436	putative homodimer-homodimer interface [polypeptide binding]; other site
235279001437	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
235279001438	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
235279001439	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
235279001440	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
235279001441	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
235279001442	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
235279001443	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
235279001444	hinge; other site
235279001445	active site
235279001446	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
235279001447	active site
235279001448	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
235279001449	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
235279001450	N-acetyl-D-glucosamine binding site [chemical binding]; other site
235279001451	catalytic residue [active]
235279001452	YGGT family; Region: YGGT; pfam02325
235279001453	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
235279001454	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
235279001455	active site
235279001456	HIGH motif; other site
235279001457	nucleotide binding site [chemical binding]; other site
235279001458	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
235279001459	active site
235279001460	KMSKS motif; other site
235279001461	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
235279001462	MarR family; Region: MarR_2; pfam12802
235279001463	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
235279001464	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
235279001465	transmembrane helices; other site
235279001466	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
235279001467	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
235279001468	metal-binding site [ion binding]
235279001469	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
235279001470	Soluble P-type ATPase [General function prediction only]; Region: COG4087
235279001471	KH domain; Region: KH_1; pfam00013
235279001472	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
235279001473	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
235279001474	Zn2+ binding site [ion binding]; other site
235279001475	Mg2+ binding site [ion binding]; other site
235279001476	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
235279001477	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
235279001478	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
235279001479	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
235279001480	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
235279001481	DNA repair protein RadA; Provisional; Region: PRK11823
235279001482	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
235279001483	Walker A motif; other site
235279001484	ATP binding site [chemical binding]; other site
235279001485	Walker B motif; other site
235279001486	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
235279001487	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
235279001488	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
235279001489	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
235279001490	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
235279001491	oligomer interface [polypeptide binding]; other site
235279001492	RNA binding site [nucleotide binding]; other site
235279001493	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
235279001494	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
235279001495	oligomer interface [polypeptide binding]; other site
235279001496	RNA binding site [nucleotide binding]; other site
235279001497	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
235279001498	putative nucleic acid binding region [nucleotide binding]; other site
235279001499	G-X-X-G motif; other site
235279001500	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
235279001501	RNA binding site [nucleotide binding]; other site
235279001502	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
235279001503	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
235279001504	Organic solvent tolerance protein; Region: OstA_C; pfam04453
235279001505	RDD family; Region: RDD; pfam06271
235279001506	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
235279001507	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
235279001508	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
235279001509	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
235279001510	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
235279001511	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
235279001512	dimerization interface 3.5A [polypeptide binding]; other site
235279001513	active site
235279001514	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
235279001515	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
235279001516	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
235279001517	Methyltransferase domain; Region: Methyltransf_18; pfam12847
235279001518	S-adenosylmethionine binding site [chemical binding]; other site
235279001519	Predicted amidohydrolase [General function prediction only]; Region: COG0388
235279001520	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
235279001521	active site
235279001522	catalytic triad [active]
235279001523	dimer interface [polypeptide binding]; other site
235279001524	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
235279001525	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
235279001526	dimer interface [polypeptide binding]; other site
235279001527	putative radical transfer pathway; other site
235279001528	diiron center [ion binding]; other site
235279001529	tyrosyl radical; other site
235279001530	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
235279001531	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
235279001532	TPP-binding site; other site
235279001533	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
235279001534	PYR/PP interface [polypeptide binding]; other site
235279001535	dimer interface [polypeptide binding]; other site
235279001536	TPP binding site [chemical binding]; other site
235279001537	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
235279001538	flagellar assembly protein H; Validated; Region: fliH; PRK06669
235279001539	Flagellar assembly protein FliH; Region: FliH; pfam02108
235279001540	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
235279001541	FliG C-terminal domain; Region: FliG_C; pfam01706
235279001542	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
235279001543	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
235279001544	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
235279001545	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
235279001546	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
235279001547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279001548	homodimer interface [polypeptide binding]; other site
235279001549	catalytic residue [active]
235279001550	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
235279001551	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
235279001552	active site
235279001553	substrate binding site [chemical binding]; other site
235279001554	metal binding site [ion binding]; metal-binding site
235279001555	dihydroorotase; Provisional; Region: PRK05451
235279001556	active site
235279001557	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
235279001558	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
235279001559	FeS/SAM binding site; other site
235279001560	HemN C-terminal domain; Region: HemN_C; pfam06969
235279001561	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
235279001562	putative active site [active]
235279001563	Ap4A binding site [chemical binding]; other site
235279001564	nudix motif; other site
235279001565	putative metal binding site [ion binding]; other site
235279001566	aspartate kinase; Reviewed; Region: PRK06635
235279001567	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
235279001568	putative catalytic residues [active]
235279001569	putative nucleotide binding site [chemical binding]; other site
235279001570	putative aspartate binding site [chemical binding]; other site
235279001571	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
235279001572	putative allosteric regulatory site; other site
235279001573	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
235279001574	putative allosteric regulatory residue; other site
235279001575	DNA replication regulator; Region: HobA; pfam12163
235279001576	DNA polymerase III subunit delta'; Validated; Region: PRK08485
235279001577	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
235279001578	dihydropteroate synthase; Region: DHPS; TIGR01496
235279001579	substrate binding pocket [chemical binding]; other site
235279001580	dimer interface [polypeptide binding]; other site
235279001581	inhibitor binding site; inhibition site
235279001582	Outer membrane efflux protein; Region: OEP; pfam02321
235279001583	Outer membrane efflux protein; Region: OEP; pfam02321
235279001584	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
235279001585	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
235279001586	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
235279001587	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
235279001588	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
235279001589	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
235279001590	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
235279001591	inhibitor-cofactor binding pocket; inhibition site
235279001592	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279001593	catalytic residue [active]
235279001594	shikimate kinase; Reviewed; Region: aroK; PRK00131
235279001595	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
235279001596	ADP binding site [chemical binding]; other site
235279001597	magnesium binding site [ion binding]; other site
235279001598	putative shikimate binding site; other site
235279001599	AMIN domain; Region: AMIN; pfam11741
235279001600	enolase; Provisional; Region: eno; PRK00077
235279001601	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
235279001602	dimer interface [polypeptide binding]; other site
235279001603	metal binding site [ion binding]; metal-binding site
235279001604	substrate binding pocket [chemical binding]; other site
235279001605	recombinase A; Provisional; Region: recA; PRK09354
235279001606	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
235279001607	hexamer interface [polypeptide binding]; other site
235279001608	Walker A motif; other site
235279001609	ATP binding site [chemical binding]; other site
235279001610	Walker B motif; other site
235279001611	Menaquinone biosynthesis; Region: VitK2_biosynth; cl17475
235279001612	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
235279001613	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
235279001614	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
235279001615	homodimer interface [polypeptide binding]; other site
235279001616	substrate-cofactor binding pocket; other site
235279001617	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279001618	catalytic residue [active]
235279001619	Homoserine O-succinyltransferase; Region: HTS; pfam04204
235279001620	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
235279001621	proposed active site lysine [active]
235279001622	conserved cys residue [active]
235279001623	Uncharacterized conserved protein [Function unknown]; Region: COG0327
235279001624	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
235279001625	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
235279001626	Putative zinc ribbon domain; Region: DUF164; pfam02591
235279001627	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
235279001628	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
235279001629	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
235279001630	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
235279001631	active site
235279001632	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
235279001633	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
235279001634	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
235279001635	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
235279001636	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
235279001637	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
235279001638	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
235279001639	Ferredoxin [Energy production and conversion]; Region: COG1146
235279001640	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
235279001641	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
235279001642	NAD binding site [chemical binding]; other site
235279001643	putative substrate binding site 2 [chemical binding]; other site
235279001644	putative substrate binding site 1 [chemical binding]; other site
235279001645	active site
235279001646	Putative lipopolysaccharide-modifying enzyme; Region: CAP10; smart00672
235279001647	L-lactate permease; Region: Lactate_perm; cl00701
235279001648	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
235279001649	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
235279001650	Cysteine-rich domain; Region: CCG; pfam02754
235279001651	Cysteine-rich domain; Region: CCG; pfam02754
235279001652	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
235279001653	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
235279001654	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
235279001655	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
235279001656	Uncharacterized conserved protein [Function unknown]; Region: COG1556
235279001657	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549
235279001658	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
235279001659	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
235279001660	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279001661	putative PBP binding loops; other site
235279001662	dimer interface [polypeptide binding]; other site
235279001663	ABC-ATPase subunit interface; other site
235279001664	ATP-binding cassette domain of the molybdenum transport system; Region: ABC_ModC_molybdenum_transporter; cd03297
235279001665	ABC-type thiamine transport system, ATPase component [Coenzyme metabolism]; Region: ThiQ; COG3840
235279001666	Walker A/P-loop; other site
235279001667	ATP binding site [chemical binding]; other site
235279001668	Q-loop/lid; other site
235279001669	ABC transporter signature motif; other site
235279001670	Walker B; other site
235279001671	D-loop; other site
235279001672	H-loop/switch region; other site
235279001673	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
235279001674	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
235279001675	Peptidase family U32; Region: Peptidase_U32; pfam01136
235279001676	peptide chain release factor 2; Validated; Region: prfB; PRK00578
235279001677	PCRF domain; Region: PCRF; pfam03462
235279001678	RF-1 domain; Region: RF-1; pfam00472
235279001679	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
235279001680	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
235279001681	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
235279001682	active site
235279001683	homotetramer interface [polypeptide binding]; other site
235279001684	homodimer interface [polypeptide binding]; other site
235279001685	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
235279001686	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
235279001687	nucleotide binding site [chemical binding]; other site
235279001688	NEF interaction site [polypeptide binding]; other site
235279001689	SBD interface [polypeptide binding]; other site
235279001690	GrpE; Region: GrpE; pfam01025
235279001691	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
235279001692	dimer interface [polypeptide binding]; other site
235279001693	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
235279001694	heat-inducible transcription repressor; Provisional; Region: PRK03911
235279001695	hypothetical protein; Provisional; Region: PRK05834
235279001696	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
235279001697	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
235279001698	metal binding site [ion binding]; metal-binding site
235279001699	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
235279001700	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
235279001701	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
235279001702	putative active site [active]
235279001703	putative metal binding site [ion binding]; other site
235279001704	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
235279001705	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
235279001706	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279001707	active site
235279001708	phosphorylation site [posttranslational modification]
235279001709	intermolecular recognition site; other site
235279001710	dimerization interface [polypeptide binding]; other site
235279001711	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
235279001712	putative binding surface; other site
235279001713	active site
235279001714	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
235279001715	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
235279001716	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279001717	ATP binding site [chemical binding]; other site
235279001718	Mg2+ binding site [ion binding]; other site
235279001719	G-X-G motif; other site
235279001720	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
235279001721	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
235279001722	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279001723	active site
235279001724	phosphorylation site [posttranslational modification]
235279001725	intermolecular recognition site; other site
235279001726	dimerization interface [polypeptide binding]; other site
235279001727	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
235279001728	putative CheA interaction surface; other site
235279001729	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
235279001730	FAD binding site [chemical binding]; other site
235279001731	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
235279001732	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
235279001733	Substrate binding site; other site
235279001734	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
235279001735	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
235279001736	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
235279001737	putative ADP-binding pocket [chemical binding]; other site
235279001738	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
235279001739	active site
235279001740	multimer interface [polypeptide binding]; other site
235279001741	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
235279001742	putative phosphate acyltransferase; Provisional; Region: PRK05331
235279001743	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
235279001744	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
235279001745	dimer interface [polypeptide binding]; other site
235279001746	active site
235279001747	CoA binding pocket [chemical binding]; other site
235279001748	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
235279001749	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
235279001750	metal-binding site [ion binding]
235279001751	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
235279001752	Soluble P-type ATPase [General function prediction only]; Region: COG4087
235279001753	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
235279001754	metal-binding site [ion binding]
235279001755	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
235279001756	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
235279001757	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279001758	Walker A/P-loop; other site
235279001759	ATP binding site [chemical binding]; other site
235279001760	Q-loop/lid; other site
235279001761	ABC transporter signature motif; other site
235279001762	Walker B; other site
235279001763	D-loop; other site
235279001764	H-loop/switch region; other site
235279001765	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
235279001766	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
235279001767	Iron-sulfur protein interface; other site
235279001768	proximal heme binding site [chemical binding]; other site
235279001769	distal heme binding site [chemical binding]; other site
235279001770	dimer interface [polypeptide binding]; other site
235279001771	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
235279001772	L-aspartate oxidase; Provisional; Region: PRK06175
235279001773	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
235279001774	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
235279001775	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
235279001776	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
235279001777	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
235279001778	putative active site [active]
235279001779	catalytic site [active]
235279001780	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
235279001781	putative active site [active]
235279001782	catalytic site [active]
235279001783	decaheme c-type cytochrome, DmsE family; Region: decahem_SO; TIGR03508
235279001784	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
235279001785	thiS-thiF/thiG interaction site; other site
235279001786	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
235279001787	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
235279001788	Substrate binding site; other site
235279001789	Mg++ binding site; other site
235279001790	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
235279001791	active site
235279001792	substrate binding site [chemical binding]; other site
235279001793	CoA binding site [chemical binding]; other site
235279001794	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
235279001795	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
235279001796	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279001797	S-adenosylmethionine binding site [chemical binding]; other site
235279001798	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
235279001799	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279001800	putative substrate translocation pore; other site
235279001801	Protein of unknown function (DUF2716); Region: DUF2716; pfam10898
235279001802	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
235279001803	Tetratricopeptide repeat; Region: TPR_12; pfam13424
235279001804	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
235279001805	binding surface
235279001806	TPR motif; other site
235279001807	Tetratricopeptide repeat; Region: TPR_16; pfam13432
235279001808	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
235279001809	RNA/DNA hybrid binding site [nucleotide binding]; other site
235279001810	active site
235279001811	ribonuclease III; Reviewed; Region: rnc; PRK00102
235279001812	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
235279001813	dimerization interface [polypeptide binding]; other site
235279001814	active site
235279001815	metal binding site [ion binding]; metal-binding site
235279001816	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
235279001817	dsRNA binding site [nucleotide binding]; other site
235279001818	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
235279001819	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
235279001820	Tetramer interface [polypeptide binding]; other site
235279001821	active site
235279001822	FMN-binding site [chemical binding]; other site
235279001823	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
235279001824	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
235279001825	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
235279001826	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
235279001827	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
235279001828	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
235279001829	active site
235279001830	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
235279001831	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
235279001832	nuclease NucT; Provisional; Region: PRK13912
235279001833	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
235279001834	putative active site [active]
235279001835	catalytic site [active]
235279001836	AAA ATPase containing von Willebrand factor type A (vWA) domain [General function prediction only]; Region: MDN1; COG5271
235279001837	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
235279001838	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
235279001839	catalytic site [active]
235279001840	G-X2-G-X-G-K; other site
235279001841	mttA/Hcf106 family; Region: MttA_Hcf106; pfam02416
235279001842	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
235279001843	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
235279001844	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
235279001845	active site
235279001846	HIGH motif; other site
235279001847	KMSK motif region; other site
235279001848	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
235279001849	tRNA binding surface [nucleotide binding]; other site
235279001850	anticodon binding site; other site
235279001851	AzlC protein; Region: AzlC; cl00570
235279001852	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
235279001853	flavodoxin FldA; Validated; Region: PRK09267
235279001854	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
235279001855	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
235279001856	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
235279001857	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
235279001858	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279001859	dimer interface [polypeptide binding]; other site
235279001860	conserved gate region; other site
235279001861	ABC-ATPase subunit interface; other site
235279001862	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
235279001863	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
235279001864	Walker A/P-loop; other site
235279001865	ATP binding site [chemical binding]; other site
235279001866	Q-loop/lid; other site
235279001867	ABC transporter signature motif; other site
235279001868	Walker B; other site
235279001869	D-loop; other site
235279001870	H-loop/switch region; other site
235279001871	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
235279001872	NIL domain; Region: NIL; pfam09383
235279001873	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
235279001874	S4 RNA-binding domain; Region: S4; smart00363
235279001875	RNA binding surface [nucleotide binding]; other site
235279001876	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
235279001877	active site
235279001878	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279001879	Sel1-like repeats; Region: SEL1; smart00671
235279001880	Sel1-like repeats; Region: SEL1; smart00671
235279001881	Sel1-like repeats; Region: SEL1; smart00671
235279001882	Sel1-like repeats; Region: SEL1; smart00671
235279001883	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
235279001884	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
235279001885	putative trimer interface [polypeptide binding]; other site
235279001886	putative CoA binding site [chemical binding]; other site
235279001887	Domain of unknown function DUF302; Region: DUF302; cl01364
235279001888	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
235279001889	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
235279001890	N-terminal plug; other site
235279001891	ligand-binding site [chemical binding]; other site
235279001892	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
235279001893	Aspartase; Region: Aspartase; cd01357
235279001894	active sites [active]
235279001895	tetramer interface [polypeptide binding]; other site
235279001896	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
235279001897	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
235279001898	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
235279001899	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279001900	dimer interface [polypeptide binding]; other site
235279001901	putative CheW interface [polypeptide binding]; other site
235279001902	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
235279001903	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
235279001904	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
235279001905	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
235279001906	dimer interface [polypeptide binding]; other site
235279001907	active site
235279001908	acyl carrier protein; Provisional; Region: acpP; PRK00982
235279001909	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279001910	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
235279001911	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
235279001912	NAD(P) binding site [chemical binding]; other site
235279001913	active site
235279001914	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
235279001915	Transglycosylase; Region: Transgly; pfam00912
235279001916	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
235279001917	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
235279001918	Bacterial Ig-like domain; Region: Big_5; pfam13205
235279001919	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
235279001920	MG2 domain; Region: A2M_N; pfam01835
235279001921	Alpha-2-macroglobulin family; Region: A2M; pfam00207
235279001922	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
235279001923	surface patch; other site
235279001924	thioester region; other site
235279001925	specificity defining residues; other site
235279001926	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
235279001927	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
235279001928	active site
235279001929	Cache domain; Region: Cache_1; pfam02743
235279001930	TH1 protein; Region: TH1; pfam04858
235279001931	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
235279001932	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
235279001933	substrate binding pocket [chemical binding]; other site
235279001934	membrane-bound complex binding site; other site
235279001935	hinge residues; other site
235279001936	methionine sulfoxide reductase A; Provisional; Region: PRK14054
235279001937	seryl-tRNA(sec) selenium transferase; Region: selA; TIGR00474
235279001938	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
235279001939	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
235279001940	catalytic residue [active]
235279001941	selenocysteine-specific elongation factor SelB; Region: selB; TIGR00475
235279001942	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
235279001943	G1 box; other site
235279001944	putative GEF interaction site [polypeptide binding]; other site
235279001945	GTP/Mg2+ binding site [chemical binding]; other site
235279001946	Switch I region; other site
235279001947	G2 box; other site
235279001948	G3 box; other site
235279001949	Switch II region; other site
235279001950	G4 box; other site
235279001951	G5 box; other site
235279001952	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
235279001953	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
235279001954	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
235279001955	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
235279001956	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
235279001957	dimer interface [polypeptide binding]; other site
235279001958	putative functional site; other site
235279001959	putative MPT binding site; other site
235279001960	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
235279001961	Ligand Binding Site [chemical binding]; other site
235279001962	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
235279001963	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
235279001964	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
235279001965	non-specific DNA binding site [nucleotide binding]; other site
235279001966	salt bridge; other site
235279001967	sequence-specific DNA binding site [nucleotide binding]; other site
235279001968	Predicted transcriptional regulator [Transcription]; Region: COG2932
235279001969	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
235279001970	Catalytic site [active]
235279001971	Integrase core domain; Region: rve; pfam00665
235279001972	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
235279001973	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279001974	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279001975	Walker A motif; other site
235279001976	Walker A/P-loop; other site
235279001977	ATP binding site [chemical binding]; other site
235279001978	ATP binding site [chemical binding]; other site
235279001979	Walker B motif; other site
235279001980	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; pfam07352
235279001981	Protein of unknown function (DUF1018); Region: DUF1018; cl01815
235279001982	Mor transcription activator family; Region: Mor; cl02360
235279001983	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
235279001984	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
235279001985	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
235279001986	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
235279001987	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
235279001988	putative metal binding site; other site
235279001989	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
235279001990	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
235279001991	Substrate binding site; other site
235279001992	metal-binding site
235279001993	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
235279001994	hypothetical protein; Provisional; Region: PRK10649
235279001995	Sulfatase; Region: Sulfatase; cl17466
235279001996	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
235279001997	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
235279001998	Walker A/P-loop; other site
235279001999	ATP binding site [chemical binding]; other site
235279002000	Q-loop/lid; other site
235279002001	ABC transporter signature motif; other site
235279002002	Walker B; other site
235279002003	D-loop; other site
235279002004	H-loop/switch region; other site
235279002005	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
235279002006	cell division protein FtsZ; Validated; Region: PRK09330
235279002007	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
235279002008	nucleotide binding site [chemical binding]; other site
235279002009	SulA interaction site; other site
235279002010	cell division protein FtsA; Region: ftsA; TIGR01174
235279002011	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
235279002012	nucleotide binding site [chemical binding]; other site
235279002013	Cell division protein FtsA; Region: FtsA; pfam14450
235279002014	SurA N-terminal domain; Region: SurA_N_3; cl07813
235279002015	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
235279002016	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
235279002017	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
235279002018	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
235279002019	RNA binding surface [nucleotide binding]; other site
235279002020	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
235279002021	active site
235279002022	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
235279002023	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
235279002024	Interdomain contacts; other site
235279002025	Cytokine receptor motif; other site
235279002026	Fibronectin type 3 domain; Region: FN3; smart00060
235279002027	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
235279002028	Interdomain contacts; other site
235279002029	Cytokine receptor motif; other site
235279002030	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279002031	S-adenosylmethionine binding site [chemical binding]; other site
235279002032	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
235279002033	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
235279002034	Walker A/P-loop; other site
235279002035	ATP binding site [chemical binding]; other site
235279002036	Q-loop/lid; other site
235279002037	ABC transporter signature motif; other site
235279002038	Walker B; other site
235279002039	D-loop; other site
235279002040	H-loop/switch region; other site
235279002041	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
235279002042	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279002043	flagellar protein FlaG; Provisional; Region: PRK08452
235279002044	flagellar capping protein; Validated; Region: fliD; PRK08453
235279002045	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
235279002046	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
235279002047	flagellar protein FliS; Validated; Region: fliS; PRK05685
235279002048	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
235279002049	IHF - DNA interface [nucleotide binding]; other site
235279002050	IHF dimer interface [polypeptide binding]; other site
235279002051	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
235279002052	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
235279002053	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
235279002054	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
235279002055	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
235279002056	GatB domain; Region: GatB_Yqey; smart00845
235279002057	PLD-like domain; Region: PLDc_2; pfam13091
235279002058	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
235279002059	putative active site [active]
235279002060	catalytic site [active]
235279002061	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279002062	ATP binding site [chemical binding]; other site
235279002063	putative Mg++ binding site [ion binding]; other site
235279002064	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
235279002065	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
235279002066	nucleotide binding region [chemical binding]; other site
235279002067	ATP-binding site [chemical binding]; other site
235279002068	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
235279002069	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
235279002070	Predicted ATPases [General function prediction only]; Region: COG1106
235279002071	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279002072	Walker A/P-loop; other site
235279002073	ATP binding site [chemical binding]; other site
235279002074	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279002075	Walker B; other site
235279002076	D-loop; other site
235279002077	H-loop/switch region; other site
235279002078	putative metal dependent hydrolase; Provisional; Region: PRK11598
235279002079	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
235279002080	Sulfatase; Region: Sulfatase; pfam00884
235279002081	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
235279002082	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
235279002083	putative catalytic cysteine [active]
235279002084	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
235279002085	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
235279002086	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
235279002087	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
235279002088	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
235279002089	Lipid A disaccharide synthetase [Cell envelope biogenesis, outer membrane]; Region: LpxB; COG0763
235279002090	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
235279002091	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
235279002092	Na2 binding site [ion binding]; other site
235279002093	putative substrate binding site 1 [chemical binding]; other site
235279002094	Na binding site 1 [ion binding]; other site
235279002095	putative substrate binding site 2 [chemical binding]; other site
235279002096	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279002097	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279002098	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279002099	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279002100	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279002101	Sel1-like repeats; Region: SEL1; smart00671
235279002102	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
235279002103	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
235279002104	FMN binding site [chemical binding]; other site
235279002105	active site
235279002106	catalytic residues [active]
235279002107	substrate binding site [chemical binding]; other site
235279002108	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
235279002109	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
235279002110	dimer interface [polypeptide binding]; other site
235279002111	active site
235279002112	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
235279002113	catalytic residues [active]
235279002114	substrate binding site [chemical binding]; other site
235279002115	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
235279002116	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
235279002117	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279002118	active site
235279002119	phosphorylation site [posttranslational modification]
235279002120	intermolecular recognition site; other site
235279002121	dimerization interface [polypeptide binding]; other site
235279002122	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
235279002123	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
235279002124	Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; cl03656
235279002125	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
235279002126	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279002127	Walker A motif; other site
235279002128	ATP binding site [chemical binding]; other site
235279002129	Walker B motif; other site
235279002130	arginine finger; other site
235279002131	Peptidase family M41; Region: Peptidase_M41; pfam01434
235279002132	Ribosomal protein L11 methylase [Translation, ribosomal structure and biogenesis]; Region: PrmA; COG2264
235279002133	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279002134	S-adenosylmethionine binding site [chemical binding]; other site
235279002135	Response regulator receiver domain; Region: Response_reg; pfam00072
235279002136	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279002137	active site
235279002138	phosphorylation site [posttranslational modification]
235279002139	intermolecular recognition site; other site
235279002140	dimerization interface [polypeptide binding]; other site
235279002141	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
235279002142	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
235279002143	catalytic residues [active]
235279002144	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
235279002145	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
235279002146	active site
235279002147	metal binding site [ion binding]; metal-binding site
235279002148	Nitronate monooxygenase; Region: NMO; pfam03060
235279002149	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
235279002150	FMN binding site [chemical binding]; other site
235279002151	substrate binding site [chemical binding]; other site
235279002152	putative catalytic residue [active]
235279002153	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
235279002154	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
235279002155	active site
235279002156	HIGH motif; other site
235279002157	dimer interface [polypeptide binding]; other site
235279002158	KMSKS motif; other site
235279002159	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
235279002160	RNA binding surface [nucleotide binding]; other site
235279002161	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
235279002162	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
235279002163	Zn2+ binding site [ion binding]; other site
235279002164	Mg2+ binding site [ion binding]; other site
235279002165	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
235279002166	synthetase active site [active]
235279002167	NTP binding site [chemical binding]; other site
235279002168	metal binding site [ion binding]; metal-binding site
235279002169	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
235279002170	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
235279002171	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
235279002172	putative nucleotide binding site [chemical binding]; other site
235279002173	uridine monophosphate binding site [chemical binding]; other site
235279002174	homohexameric interface [polypeptide binding]; other site
235279002175	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279002176	S-adenosylmethionine binding site [chemical binding]; other site
235279002177	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
235279002178	catalytic motif [active]
235279002179	Zn binding site [ion binding]; other site
235279002180	RibD C-terminal domain; Region: RibD_C; cl17279
235279002181	ribosome maturation protein RimP; Reviewed; Region: PRK00092
235279002182	Sm and related proteins; Region: Sm_like; cl00259
235279002183	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
235279002184	putative oligomer interface [polypeptide binding]; other site
235279002185	putative RNA binding site [nucleotide binding]; other site
235279002186	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
235279002187	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
235279002188	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
235279002189	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
235279002190	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
235279002191	flagellar assembly protein FliW; Provisional; Region: PRK13282
235279002192	Tetratricopeptide repeat; Region: TPR_18; pfam13512
235279002193	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
235279002194	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279002195	Walker A motif; other site
235279002196	ATP binding site [chemical binding]; other site
235279002197	Walker B motif; other site
235279002198	arginine finger; other site
235279002199	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
235279002200	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
235279002201	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279002202	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
235279002203	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
235279002204	dimer interface [polypeptide binding]; other site
235279002205	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279002206	catalytic residue [active]
235279002207	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
235279002208	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
235279002209	FAD binding site [chemical binding]; other site
235279002210	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
235279002211	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
235279002212	THF binding site; other site
235279002213	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
235279002214	substrate binding site [chemical binding]; other site
235279002215	THF binding site; other site
235279002216	zinc-binding site [ion binding]; other site
235279002217	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
235279002218	dimerization interface [polypeptide binding]; other site
235279002219	substrate binding site [chemical binding]; other site
235279002220	active site
235279002221	calcium binding site [ion binding]; other site
235279002222	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
235279002223	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
235279002224	glutaminase active site [active]
235279002225	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
235279002226	dimer interface [polypeptide binding]; other site
235279002227	active site
235279002228	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
235279002229	dimer interface [polypeptide binding]; other site
235279002230	active site
235279002231	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
235279002232	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
235279002233	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
235279002234	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279002235	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
235279002236	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279002237	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
235279002238	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
235279002239	motif 1; other site
235279002240	active site
235279002241	motif 2; other site
235279002242	motif 3; other site
235279002243	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
235279002244	DHHA1 domain; Region: DHHA1; pfam02272
235279002245	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
235279002246	active site
235279002247	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
235279002248	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
235279002249	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
235279002250	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
235279002251	active site
235279002252	hydrophilic channel; other site
235279002253	dimerization interface [polypeptide binding]; other site
235279002254	catalytic residues [active]
235279002255	active site lid [active]
235279002256	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
235279002257	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
235279002258	putative valine binding site [chemical binding]; other site
235279002259	dimer interface [polypeptide binding]; other site
235279002260	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
235279002261	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK08527
235279002262	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
235279002263	PYR/PP interface [polypeptide binding]; other site
235279002264	dimer interface [polypeptide binding]; other site
235279002265	TPP binding site [chemical binding]; other site
235279002266	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
235279002267	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
235279002268	TPP-binding site [chemical binding]; other site
235279002269	dimer interface [polypeptide binding]; other site
235279002270	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
235279002271	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279002272	putative substrate translocation pore; other site
235279002273	Lumazine-binding domain; Region: Lumazine_bd; pfam12870
235279002274	FAD binding domain; Region: FAD_binding_4; pfam01565
235279002275	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
235279002276	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
235279002277	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
235279002278	dimer interface [polypeptide binding]; other site
235279002279	ADP-ribose binding site [chemical binding]; other site
235279002280	active site
235279002281	nudix motif; other site
235279002282	metal binding site [ion binding]; metal-binding site
235279002283	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
235279002284	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279002285	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
235279002286	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
235279002287	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
235279002288	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
235279002289	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279002290	Walker B motif; other site
235279002291	arginine finger; other site
235279002292	Peptidase family M41; Region: Peptidase_M41; pfam01434
235279002293	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
235279002294	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
235279002295	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
235279002296	FeS/SAM binding site; other site
235279002297	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
235279002298	Mechanosensitive ion channel; Region: MS_channel; pfam00924
235279002299	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
235279002300	active site
235279002301	dimer interface [polypeptide binding]; other site
235279002302	metal binding site [ion binding]; metal-binding site
235279002303	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
235279002304	TrkA-C domain; Region: TrkA_C; pfam02080
235279002305	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
235279002306	Protein of unknown function (DUF493); Region: DUF493; pfam04359
235279002307	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
235279002308	active site
235279002309	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
235279002310	putative substrate binding site 2 [chemical binding]; other site
235279002311	putative substrate binding site 1 [chemical binding]; other site
235279002312	Na binding site 1 [ion binding]; other site
235279002313	Na2 binding site [ion binding]; other site
235279002314	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
235279002315	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
235279002316	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
235279002317	catalytic site [active]
235279002318	subunit interface [polypeptide binding]; other site
235279002319	Protein of unknown function (DUF507); Region: DUF507; pfam04368
235279002320	Transglycosylase; Region: Transgly; pfam00912
235279002321	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
235279002322	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
235279002323	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279002324	dimer interface [polypeptide binding]; other site
235279002325	putative CheW interface [polypeptide binding]; other site
235279002326	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
235279002327	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
235279002328	metal binding site 2 [ion binding]; metal-binding site
235279002329	putative DNA binding helix; other site
235279002330	metal binding site 1 [ion binding]; metal-binding site
235279002331	dimer interface [polypeptide binding]; other site
235279002332	structural Zn2+ binding site [ion binding]; other site
235279002333	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
235279002334	threonine dehydratase; Provisional; Region: PRK08526
235279002335	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
235279002336	tetramer interface [polypeptide binding]; other site
235279002337	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279002338	catalytic residue [active]
235279002339	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
235279002340	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
235279002341	EamA-like transporter family; Region: EamA; pfam00892
235279002342	EamA-like transporter family; Region: EamA; cl17759
235279002343	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
235279002344	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
235279002345	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
235279002346	ligand binding site; other site
235279002347	tetramer interface; other site
235279002348	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
235279002349	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
235279002350	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
235279002351	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
235279002352	pseudaminic acid synthase; Region: PseI; TIGR03586
235279002353	NeuB family; Region: NeuB; pfam03102
235279002354	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
235279002355	NeuB binding interface [polypeptide binding]; other site
235279002356	putative substrate binding site [chemical binding]; other site
235279002357	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
235279002358	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
235279002359	catalytic residue [active]
235279002360	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
235279002361	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
235279002362	thiamine-phosphate pyrophosphorylase; Provisional; Region: PRK02615
235279002363	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
235279002364	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
235279002365	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
235279002366	4Fe-4S binding domain; Region: Fer4_5; pfam12801
235279002367	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
235279002368	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
235279002369	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
235279002370	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279002371	Walker A/P-loop; other site
235279002372	ATP binding site [chemical binding]; other site
235279002373	Q-loop/lid; other site
235279002374	ABC transporter signature motif; other site
235279002375	Walker B; other site
235279002376	D-loop; other site
235279002377	H-loop/switch region; other site
235279002378	ABC transporter; Region: ABC_tran_2; pfam12848
235279002379	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
235279002380	Phytoreovirus S7 protein; Region: Phytoreo_S7; pfam07236
235279002381	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
235279002382	non-specific DNA binding site [nucleotide binding]; other site
235279002383	salt bridge; other site
235279002384	sequence-specific DNA binding site [nucleotide binding]; other site
235279002385	Competence-damaged protein; Region: CinA; pfam02464
235279002386	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
235279002387	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
235279002388	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
235279002389	active site
235279002390	zinc binding site [ion binding]; other site
235279002391	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
235279002392	active site residue [active]
235279002393	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
235279002394	Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539
235279002395	active site
235279002396	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279002397	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279002398	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
235279002399	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
235279002400	active site
235279002401	HIGH motif; other site
235279002402	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
235279002403	active site
235279002404	KMSKS motif; other site
235279002405	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
235279002406	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
235279002407	active site
235279002408	homodimer interface [polypeptide binding]; other site
235279002409	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
235279002410	active site
235279002411	putative catalytic site [active]
235279002412	DNA binding site [nucleotide binding]
235279002413	putative phosphate binding site [ion binding]; other site
235279002414	metal binding site A [ion binding]; metal-binding site
235279002415	AP binding site [nucleotide binding]; other site
235279002416	metal binding site B [ion binding]; metal-binding site
235279002417	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_2; cd10034
235279002418	putative uracil binding site [chemical binding]; other site
235279002419	putative active site [active]
235279002420	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
235279002421	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
235279002422	Part of AAA domain; Region: AAA_19; pfam13245
235279002423	Family description; Region: UvrD_C_2; pfam13538
235279002424	flagellar assembly protein FliW; Provisional; Region: PRK13283
235279002425	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
235279002426	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
235279002427	active site
235279002428	HIGH motif; other site
235279002429	nucleotide binding site [chemical binding]; other site
235279002430	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
235279002431	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
235279002432	active site
235279002433	KMSKS motif; other site
235279002434	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
235279002435	tRNA binding surface [nucleotide binding]; other site
235279002436	anticodon binding site; other site
235279002437	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
235279002438	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
235279002439	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
235279002440	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
235279002441	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
235279002442	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
235279002443	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
235279002444	KH domain; Region: KH_4; pfam13083
235279002445	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
235279002446	signal recognition particle protein; Provisional; Region: PRK10867
235279002447	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
235279002448	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
235279002449	P loop; other site
235279002450	GTP binding site [chemical binding]; other site
235279002451	Signal peptide binding domain; Region: SRP_SPB; pfam02978
235279002452	ferric uptake regulator; Provisional; Region: fur; PRK09462
235279002453	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
235279002454	metal binding site 2 [ion binding]; metal-binding site
235279002455	putative DNA binding helix; other site
235279002456	metal binding site 1 [ion binding]; metal-binding site
235279002457	dimer interface [polypeptide binding]; other site
235279002458	structural Zn2+ binding site [ion binding]; other site
235279002459	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
235279002460	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
235279002461	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
235279002462	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
235279002463	active site
235279002464	Dehydroquinase class II; Region: DHquinase_II; pfam01220
235279002465	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
235279002466	trimer interface [polypeptide binding]; other site
235279002467	active site
235279002468	dimer interface [polypeptide binding]; other site
235279002469	Flagellin N-methylase; Region: FliB; pfam03692
235279002470	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
235279002471	non-specific DNA binding site [nucleotide binding]; other site
235279002472	salt bridge; other site
235279002473	sequence-specific DNA binding site [nucleotide binding]; other site
235279002474	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
235279002475	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
235279002476	molybdopterin cofactor binding site [chemical binding]; other site
235279002477	substrate binding site [chemical binding]; other site
235279002478	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
235279002479	molybdopterin cofactor binding site; other site
235279002480	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
235279002481	Uncharacterized conserved protein [Function unknown]; Region: COG3334
235279002482	Flagellar FliJ protein; Region: FliJ; pfam02050
235279002483	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
235279002484	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
235279002485	GDP-binding site [chemical binding]; other site
235279002486	ACT binding site; other site
235279002487	IMP binding site; other site
235279002488	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12293
235279002489	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
235279002490	motif 1; other site
235279002491	dimer interface [polypeptide binding]; other site
235279002492	active site
235279002493	motif 2; other site
235279002494	motif 3; other site
235279002495	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
235279002496	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
235279002497	Ligand Binding Site [chemical binding]; other site
235279002498	Initiator Replication protein; Region: Rep_3; cl17676
235279002499	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
235279002500	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
235279002501	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
235279002502	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
235279002503	inhibitor-cofactor binding pocket; inhibition site
235279002504	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279002505	catalytic residue [active]
235279002506	YceI-like domain; Region: YceI; pfam04264
235279002507	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
235279002508	acetylornithine aminotransferase; Provisional; Region: PRK02627
235279002509	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
235279002510	inhibitor-cofactor binding pocket; inhibition site
235279002511	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279002512	catalytic residue [active]
235279002513	Uncharacterized conserved protein [Function unknown]; Region: COG1565
235279002514	Cache domain; Region: Cache_1; pfam02743
235279002515	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279002516	dimer interface [polypeptide binding]; other site
235279002517	putative CheW interface [polypeptide binding]; other site
235279002518	Predicted signal transduction protein [Signal transduction mechanisms]; Region: COG1639
235279002519	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
235279002520	Cysteine-rich domain; Region: CCG; pfam02754
235279002521	Cysteine-rich domain; Region: CCG; pfam02754
235279002522	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
235279002523	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279002524	FeS/SAM binding site; other site
235279002525	HemN C-terminal domain; Region: HemN_C; pfam06969
235279002526	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
235279002527	ornithine carbamoyltransferase; Provisional; Region: PRK00779
235279002528	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
235279002529	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
235279002530	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
235279002531	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
235279002532	active site
235279002533	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
235279002534	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
235279002535	putative ADP-binding pocket [chemical binding]; other site
235279002536	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
235279002537	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
235279002538	putative acyl-acceptor binding pocket; other site
235279002539	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
235279002540	lipopolysaccharide heptosyltransferase I; Region: heptsyl_trn_I; TIGR02193
235279002541	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
235279002542	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
235279002543	nucleotide binding site [chemical binding]; other site
235279002544	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
235279002545	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
235279002546	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
235279002547	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
235279002548	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
235279002549	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
235279002550	hypothetical protein; Provisional; Region: PRK08445
235279002551	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279002552	FeS/SAM binding site; other site
235279002553	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
235279002554	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
235279002555	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
235279002556	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
235279002557	Surface antigen; Region: Bac_surface_Ag; pfam01103
235279002558	prephenate dehydrogenase; Validated; Region: PRK08507
235279002559	Prephenate dehydrogenase; Region: PDH; pfam02153
235279002560	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
235279002561	RNA methyltransferase, RsmE family; Region: TIGR00046
235279002562	ferrochelatase; Reviewed; Region: hemH; PRK00035
235279002563	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
235279002564	active site
235279002565	C-terminal domain interface [polypeptide binding]; other site
235279002566	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
235279002567	active site
235279002568	N-terminal domain interface [polypeptide binding]; other site
235279002569	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
235279002570	catalytic residues [active]
235279002571	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
235279002572	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
235279002573	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
235279002574	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
235279002575	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
235279002576	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
235279002577	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
235279002578	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
235279002579	Walker A/P-loop; other site
235279002580	ATP binding site [chemical binding]; other site
235279002581	Q-loop/lid; other site
235279002582	ABC transporter signature motif; other site
235279002583	Walker B; other site
235279002584	D-loop; other site
235279002585	H-loop/switch region; other site
235279002586	Uncharacterized conserved protein [Function unknown]; Region: COG2353
235279002587	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
235279002588	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
235279002589	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
235279002590	intrachain domain interface; other site
235279002591	interchain domain interface [polypeptide binding]; other site
235279002592	heme bH binding site [chemical binding]; other site
235279002593	Qi binding site; other site
235279002594	heme bL binding site [chemical binding]; other site
235279002595	Qo binding site; other site
235279002596	interchain domain interface [polypeptide binding]; other site
235279002597	intrachain domain interface; other site
235279002598	Qi binding site; other site
235279002599	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
235279002600	Qo binding site; other site
235279002601	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
235279002602	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
235279002603	[2Fe-2S] cluster binding site [ion binding]; other site
235279002604	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
235279002605	homodimer interface [polypeptide binding]; other site
235279002606	NAD synthase; Region: NAD_synthase; pfam02540
235279002607	NAD binding pocket [chemical binding]; other site
235279002608	ATP binding pocket [chemical binding]; other site
235279002609	Mg binding site [ion binding]; other site
235279002610	active-site loop [active]
235279002611	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
235279002612	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
235279002613	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
235279002614	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
235279002615	catalytic triad [active]
235279002616	translation initiation factor IF-2; Region: IF-2; TIGR00487
235279002617	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
235279002618	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
235279002619	G1 box; other site
235279002620	putative GEF interaction site [polypeptide binding]; other site
235279002621	GTP/Mg2+ binding site [chemical binding]; other site
235279002622	Switch I region; other site
235279002623	G2 box; other site
235279002624	G3 box; other site
235279002625	Switch II region; other site
235279002626	G4 box; other site
235279002627	G5 box; other site
235279002628	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
235279002629	Translation-initiation factor 2; Region: IF-2; pfam11987
235279002630	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
235279002631	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cl00189
235279002632	putative RNA binding cleft [nucleotide binding]; other site
235279002633	homoserine kinase; Provisional; Region: PRK01212
235279002634	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
235279002635	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
235279002636	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
235279002637	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
235279002638	septum formation inhibitor; Reviewed; Region: minC; PRK00556
235279002639	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
235279002640	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
235279002641	Peptidase family M23; Region: Peptidase_M23; pfam01551
235279002642	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
235279002643	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
235279002644	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
235279002645	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
235279002646	GTP binding site; other site
235279002647	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
235279002648	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279002649	FeS/SAM binding site; other site
235279002650	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
235279002651	hypothetical protein; Provisional; Region: PRK08444
235279002652	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279002653	FeS/SAM binding site; other site
235279002654	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
235279002655	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
235279002656	metal-binding site [ion binding]
235279002657	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
235279002658	Soluble P-type ATPase [General function prediction only]; Region: COG4087
235279002659	ATP-grasp domain; Region: ATP-grasp_4; cl17255
235279002660	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
235279002661	Part of AAA domain; Region: AAA_19; pfam13245
235279002662	AAA domain; Region: AAA_12; pfam13087
235279002663	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
235279002664	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
235279002665	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
235279002666	active site
235279002667	catalytic tetrad [active]
235279002668	hypothetical protein; Provisional; Region: PRK10621
235279002669	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
235279002670	Protein of unknown function DUF262; Region: DUF262; pfam03235
235279002671	Uncharacterized conserved protein [Function unknown]; Region: COG1479
235279002672	Uncharacterized conserved protein [Function unknown]; Region: COG1479
235279002673	Protein of unknown function DUF262; Region: DUF262; pfam03235
235279002674	flavodoxin; Provisional; Region: PRK07116
235279002675	Uncharacterized conserved protein [Function unknown]; Region: COG4925
235279002676	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
235279002677	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
235279002678	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
235279002679	active site
235279002680	catalytic tetrad [active]
235279002681	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
235279002682	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
235279002683	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
235279002684	DNA binding site [nucleotide binding]
235279002685	active site
235279002686	DNA methylase; Region: N6_N4_Mtase; cl17433
235279002687	Domain of unknown function DUF87; Region: DUF87; pfam01935
235279002688	HerA helicase [Replication, recombination, and repair]; Region: COG0433
235279002689	NurA nuclease; Region: NurA; smart00933
235279002690	TfoX N-terminal domain; Region: TfoX_N; cl17592
235279002691	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
235279002692	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
235279002693	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_22; cd08359
235279002694	putative dimer interface [polypeptide binding]; other site
235279002695	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
235279002696	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
235279002697	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
235279002698	trimer interface [polypeptide binding]; other site
235279002699	active site
235279002700	substrate binding site [chemical binding]; other site
235279002701	CoA binding site [chemical binding]; other site
235279002702	Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999
235279002703	active site
235279002704	Mn binding site [ion binding]; other site
235279002705	von Willebrand factor type A domain; Region: VWA_2; pfam13519
235279002706	metal ion-dependent adhesion site (MIDAS); other site
235279002707	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
235279002708	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
235279002709	ICEA Protein; Region: ICEA; pfam05315
235279002710	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
235279002711	Predicted transcriptional regulators [Transcription]; Region: COG1733
235279002712	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
235279002713	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
235279002714	NADH(P)-binding; Region: NAD_binding_10; pfam13460
235279002715	NAD binding site [chemical binding]; other site
235279002716	substrate binding site [chemical binding]; other site
235279002717	putative active site [active]
235279002718	DoxX; Region: DoxX; pfam07681
235279002719	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
235279002720	Uncharacterized conserved protein [Function unknown]; Region: COG1479
235279002721	Protein of unknown function DUF262; Region: DUF262; pfam03235
235279002722	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
235279002723	hypothetical protein; Provisional; Region: PRK02268
235279002724	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
235279002725	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion Channel-Associated 1); Region: TDT_SLAC1_like; cd09323
235279002726	gating phenylalanine in ion channel; other site
235279002727	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
235279002728	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
235279002729	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
235279002730	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
235279002731	elongation factor Ts; Provisional; Region: tsf; PRK09377
235279002732	UBA/TS-N domain; Region: UBA; pfam00627
235279002733	Elongation factor TS; Region: EF_TS; pfam00889
235279002734	Elongation factor TS; Region: EF_TS; pfam00889
235279002735	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
235279002736	rRNA interaction site [nucleotide binding]; other site
235279002737	S8 interaction site; other site
235279002738	putative laminin-1 binding site; other site
235279002739	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
235279002740	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
235279002741	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
235279002742	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
235279002743	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
235279002744	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
235279002745	Walker A/P-loop; other site
235279002746	ATP binding site [chemical binding]; other site
235279002747	Q-loop/lid; other site
235279002748	ABC transporter signature motif; other site
235279002749	Walker B; other site
235279002750	D-loop; other site
235279002751	H-loop/switch region; other site
235279002752	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
235279002753	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
235279002754	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279002755	Walker A motif; other site
235279002756	ATP binding site [chemical binding]; other site
235279002757	Walker B motif; other site
235279002758	arginine finger; other site
235279002759	Predicted membrane protein [Function unknown]; Region: COG2860
235279002760	UPF0126 domain; Region: UPF0126; pfam03458
235279002761	UPF0126 domain; Region: UPF0126; pfam03458
235279002762	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
235279002763	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
235279002764	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
235279002765	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
235279002766	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
235279002767	active site
235279002768	oxyanion hole [active]
235279002769	catalytic triad [active]
235279002770	SGNH_peri2; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri2; cd01829
235279002771	active site
235279002772	catalytic triad [active]
235279002773	oxyanion hole [active]
235279002774	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
235279002775	TLC ATP/ADP transporter; Region: TLC; cl03940
235279002776	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
235279002777	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
235279002778	DNA binding residues [nucleotide binding]
235279002779	putative dimer interface [polypeptide binding]; other site
235279002780	Cache domain; Region: Cache_1; pfam02743
235279002781	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279002782	dimer interface [polypeptide binding]; other site
235279002783	putative CheW interface [polypeptide binding]; other site
235279002784	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
235279002785	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
235279002786	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
235279002787	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
235279002788	Methyltransferase domain; Region: Methyltransf_26; pfam13659
235279002789	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
235279002790	putative trimer interface [polypeptide binding]; other site
235279002791	putative active site [active]
235279002792	putative substrate binding site [chemical binding]; other site
235279002793	putative CoA binding site [chemical binding]; other site
235279002794	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
235279002795	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
235279002796	catalytic residue [active]
235279002797	putative FPP diphosphate  binding site; other site
235279002798	putative FPP binding hydrophobic cleft; other site
235279002799	dimer interface [polypeptide binding]; other site
235279002800	putative IPP diphosphate binding site; other site
235279002801	Malic enzyme, N-terminal domain; Region: malic; pfam00390
235279002802	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
235279002803	putative NAD(P) binding site [chemical binding]; other site
235279002804	Restriction endonuclease; Region: Mrr_cat; pfam04471
235279002805	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
235279002806	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
235279002807	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
235279002808	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
235279002809	trimer interface [polypeptide binding]; other site
235279002810	active site
235279002811	UDP-GlcNAc binding site [chemical binding]; other site
235279002812	lipid binding site [chemical binding]; lipid-binding site
235279002813	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
235279002814	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
235279002815	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
235279002816	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
235279002817	Cytochrome bd-type quinol oxidase, subunit 1 [Energy production and conversion]; Region: CydA; COG1271
235279002818	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
235279002819	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
235279002820	Dynamin family; Region: Dynamin_N; pfam00350
235279002821	G1 box; other site
235279002822	GTP/Mg2+ binding site [chemical binding]; other site
235279002823	G2 box; other site
235279002824	Switch I region; other site
235279002825	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
235279002826	G3 box; other site
235279002827	Switch II region; other site
235279002828	GTP/Mg2+ binding site [chemical binding]; other site
235279002829	G4 box; other site
235279002830	G5 box; other site
235279002831	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
235279002832	Dynamin family; Region: Dynamin_N; pfam00350
235279002833	G1 box; other site
235279002834	GTP/Mg2+ binding site [chemical binding]; other site
235279002835	G2 box; other site
235279002836	Switch I region; other site
235279002837	G3 box; other site
235279002838	Switch II region; other site
235279002839	G4 box; other site
235279002840	G5 box; other site
235279002841	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279002842	putative substrate translocation pore; other site
235279002843	Major Facilitator Superfamily; Region: MFS_1; pfam07690
235279002844	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
235279002845	DnaA N-terminal domain; Region: DnaA_N; pfam11638
235279002846	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279002847	Walker A motif; other site
235279002848	ATP binding site [chemical binding]; other site
235279002849	Walker B motif; other site
235279002850	arginine finger; other site
235279002851	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
235279002852	DnaA box-binding interface [nucleotide binding]; other site
235279002853	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
235279002854	active site
235279002855	putative DNA-binding cleft [nucleotide binding]; other site
235279002856	dimer interface [polypeptide binding]; other site
235279002857	Protein of unknown function (DUF1268); Region: DUF1268; pfam06896
235279002858	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
235279002859	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
235279002860	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
235279002861	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
235279002862	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
235279002863	Walker A motif; other site
235279002864	ATP binding site [chemical binding]; other site
235279002865	Walker B motif; other site
235279002866	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
235279002867	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
235279002868	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
235279002869	Uncharacterized protein conserved in archaea [Function unknown]; Region: COG1817
235279002870	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
235279002871	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
235279002872	mce related protein; Region: MCE; pfam02470
235279002873	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
235279002874	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279002875	Walker A/P-loop; other site
235279002876	ATP binding site [chemical binding]; other site
235279002877	Q-loop/lid; other site
235279002878	ABC transporter signature motif; other site
235279002879	Walker B; other site
235279002880	D-loop; other site
235279002881	H-loop/switch region; other site
235279002882	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
235279002883	Permease; Region: Permease; cl00510
235279002884	DNA polymerase III subunit beta; Validated; Region: PRK05643
235279002885	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
235279002886	putative DNA binding surface [nucleotide binding]; other site
235279002887	dimer interface [polypeptide binding]; other site
235279002888	beta-clamp/clamp loader binding surface; other site
235279002889	beta-clamp/translesion DNA polymerase binding surface; other site
235279002890	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
235279002891	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279002892	Mg2+ binding site [ion binding]; other site
235279002893	G-X-G motif; other site
235279002894	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
235279002895	anchoring element; other site
235279002896	dimer interface [polypeptide binding]; other site
235279002897	ATP binding site [chemical binding]; other site
235279002898	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
235279002899	active site
235279002900	putative metal-binding site [ion binding]; other site
235279002901	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
235279002902	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
235279002903	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
235279002904	3-isopropylmalate dehydratase, small subunit; Region: leud; TIGR02084
235279002905	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
235279002906	substrate binding site [chemical binding]; other site
235279002907	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
235279002908	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
235279002909	substrate binding site [chemical binding]; other site
235279002910	ligand binding site [chemical binding]; other site
235279002911	2-isopropylmalate synthase; Validated; Region: PRK03739
235279002912	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
235279002913	active site
235279002914	catalytic residues [active]
235279002915	metal binding site [ion binding]; metal-binding site
235279002916	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
235279002917	transaldolase; Provisional; Region: PRK03903
235279002918	Class I aldolases; Region: Aldolase_Class_I; cl17187
235279002919	catalytic residue [active]
235279002920	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
235279002921	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
235279002922	catalytic center binding site [active]
235279002923	ATP binding site [chemical binding]; other site
235279002924	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
235279002925	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
235279002926	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
235279002927	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
235279002928	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
235279002929	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
235279002930	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
235279002931	Sigma-70, region 4; Region: Sigma70_r4; pfam04545
235279002932	DNA binding residues [nucleotide binding]
235279002933	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
235279002934	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
235279002935	flagellar motor switch protein FliY; Validated; Region: PRK08432
235279002936	flagellar motor switch protein FliN; Region: fliN; TIGR02480
235279002937	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
235279002938	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
235279002939	ligand binding site [chemical binding]; other site
235279002940	flexible hinge region; other site
235279002941	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
235279002942	non-specific DNA interactions [nucleotide binding]; other site
235279002943	DNA binding site [nucleotide binding]
235279002944	sequence specific DNA binding site [nucleotide binding]; other site
235279002945	putative cAMP binding site [chemical binding]; other site
235279002946	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
235279002947	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
235279002948	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
235279002949	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
235279002950	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
235279002951	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
235279002952	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
235279002953	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279002954	dimer interface [polypeptide binding]; other site
235279002955	putative CheW interface [polypeptide binding]; other site
235279002956	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
235279002957	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
235279002958	ssDNA binding site; other site
235279002959	generic binding surface II; other site
235279002960	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279002961	ATP binding site [chemical binding]; other site
235279002962	putative Mg++ binding site [ion binding]; other site
235279002963	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
235279002964	nucleotide binding region [chemical binding]; other site
235279002965	ATP-binding site [chemical binding]; other site
235279002966	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
235279002967	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
235279002968	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
235279002969	short chain dehydrogenase; Provisional; Region: PRK07024
235279002970	classical (c) SDR, subgroup 6; Region: SDR_c6; cd05350
235279002971	putative NAD(P) binding site [chemical binding]; other site
235279002972	active site
235279002973	Sulfatase; Region: Sulfatase; pfam00884
235279002974	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
235279002975	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
235279002976	catalytic residues [active]
235279002977	Predicted membrane protein [Function unknown]; Region: COG2855
235279002978	YceI-like domain; Region: YceI; pfam04264
235279002979	Transcriptional regulators [Transcription]; Region: MarR; COG1846
235279002980	MarR family; Region: MarR_2; cl17246
235279002981	MarR family; Region: MarR_2; cl17246
235279002982	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
235279002983	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
235279002984	active site
235279002985	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
235279002986	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
235279002987	Sulfatase; Region: Sulfatase; pfam00884
235279002988	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
235279002989	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
235279002990	putative NAD(P) binding site [chemical binding]; other site
235279002991	putative substrate binding site [chemical binding]; other site
235279002992	catalytic Zn binding site [ion binding]; other site
235279002993	structural Zn binding site [ion binding]; other site
235279002994	dimer interface [polypeptide binding]; other site
235279002995	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
235279002996	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
235279002997	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
235279002998	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
235279002999	Mg++ binding site [ion binding]; other site
235279003000	putative catalytic motif [active]
235279003001	putative substrate binding site [chemical binding]; other site
235279003002	phosphoglyceromutase; Provisional; Region: PRK05434
235279003003	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
235279003004	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
235279003005	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
235279003006	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
235279003007	KpsF/GutQ family protein; Region: kpsF; TIGR00393
235279003008	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
235279003009	putative active site [active]
235279003010	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
235279003011	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
235279003012	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
235279003013	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
235279003014	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
235279003015	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
235279003016	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
235279003017	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
235279003018	substrate binding site [chemical binding]; other site
235279003019	glutamase interaction surface [polypeptide binding]; other site
235279003020	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
235279003021	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
235279003022	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279003023	FeS/SAM binding site; other site
235279003024	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
235279003025	Ligand Binding Site [chemical binding]; other site
235279003026	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
235279003027	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
235279003028	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
235279003029	active site
235279003030	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
235279003031	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
235279003032	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
235279003033	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279003034	Walker A motif; other site
235279003035	ATP binding site [chemical binding]; other site
235279003036	Walker B motif; other site
235279003037	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
235279003038	rod shape-determining protein MreB; Provisional; Region: PRK13927
235279003039	MreB and similar proteins; Region: MreB_like; cd10225
235279003040	nucleotide binding site [chemical binding]; other site
235279003041	Mg binding site [ion binding]; other site
235279003042	putative protofilament interaction site [polypeptide binding]; other site
235279003043	RodZ interaction site [polypeptide binding]; other site
235279003044	rod shape-determining protein MreC; Provisional; Region: PRK13922
235279003045	rod shape-determining protein MreC; Region: MreC; pfam04085
235279003046	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279003047	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279003048	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279003049	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279003050	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279003051	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
235279003052	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
235279003053	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
235279003054	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
235279003055	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
235279003056	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
235279003057	active site
235279003058	HIGH motif; other site
235279003059	nucleotide binding site [chemical binding]; other site
235279003060	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
235279003061	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
235279003062	active site
235279003063	KMSKS motif; other site
235279003064	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
235279003065	tRNA binding surface [nucleotide binding]; other site
235279003066	anticodon binding site; other site
235279003067	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
235279003068	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
235279003069	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
235279003070	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
235279003071	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
235279003072	Ligand Binding Site [chemical binding]; other site
235279003073	DNA primase, catalytic core; Region: dnaG; TIGR01391
235279003074	CHC2 zinc finger; Region: zf-CHC2; pfam01807
235279003075	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
235279003076	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
235279003077	active site
235279003078	metal binding site [ion binding]; metal-binding site
235279003079	interdomain interaction site; other site
235279003080	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
235279003081	oligomerisation interface [polypeptide binding]; other site
235279003082	mobile loop; other site
235279003083	roof hairpin; other site
235279003084	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
235279003085	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
235279003086	ring oligomerisation interface [polypeptide binding]; other site
235279003087	ATP/Mg binding site [chemical binding]; other site
235279003088	stacking interactions; other site
235279003089	hinge regions; other site
235279003090	Phage protein Gp37/Gp68; Region: Gp37_Gp68; cl15384
235279003091	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
235279003092	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
235279003093	ketol-acid reductoisomerase; Provisional; Region: PRK05479
235279003094	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
235279003095	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
235279003096	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
235279003097	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
235279003098	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
235279003099	TrkA-N domain; Region: TrkA_N; pfam02254
235279003100	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
235279003101	Methyltransferase domain; Region: Methyltransf_12; pfam08242
235279003102	Protein of unknown function (DUF452); Region: DUF452; cl01062
235279003103	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
235279003104	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
235279003105	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
235279003106	catalytic residue [active]
235279003107	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
235279003108	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
235279003109	inhibitor-cofactor binding pocket; inhibition site
235279003110	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279003111	catalytic residue [active]
235279003112	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
235279003113	AAA domain; Region: AAA_26; pfam13500
235279003114	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
235279003115	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
235279003116	dimer interface [polypeptide binding]; other site
235279003117	active site
235279003118	non-prolyl cis peptide bond; other site
235279003119	insertion regions; other site
235279003120	ATP-grasp domain; Region: ATP-grasp_4; cl17255
235279003121	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
235279003122	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
235279003123	active site
235279003124	non-prolyl cis peptide bond; other site
235279003125	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
235279003126	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
235279003127	putative heme binding pocket [chemical binding]; other site
235279003128	Cation efflux family; Region: Cation_efflux; cl00316
235279003129	argininosuccinate synthase; Provisional; Region: PRK13820
235279003130	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
235279003131	ANP binding site [chemical binding]; other site
235279003132	Substrate Binding Site II [chemical binding]; other site
235279003133	Substrate Binding Site I [chemical binding]; other site
235279003134	Protein of unknown function (DUF3897); Region: DUF3897; pfam13036
235279003135	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279003136	Sel1-like repeats; Region: SEL1; smart00671
235279003137	Sel1-like repeats; Region: SEL1; smart00671
235279003138	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
235279003139	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
235279003140	P-loop; other site
235279003141	ADP binding residues [chemical binding]; other site
235279003142	Switch I; other site
235279003143	Switch II; other site
235279003144	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
235279003145	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
235279003146	NodB motif; other site
235279003147	putative active site [active]
235279003148	putative catalytic site [active]
235279003149	Zn binding site [ion binding]; other site
235279003150	DNA protecting protein DprA; Region: dprA; TIGR00732
235279003151	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
235279003152	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
235279003153	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
235279003154	metal-binding heat shock protein; Provisional; Region: PRK00016
235279003155	arginine decarboxylase; Provisional; Region: PRK05354
235279003156	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
235279003157	dimer interface [polypeptide binding]; other site
235279003158	active site
235279003159	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
235279003160	catalytic residues [active]
235279003161	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
235279003162	serine O-acetyltransferase; Region: cysE; TIGR01172
235279003163	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
235279003164	trimer interface [polypeptide binding]; other site
235279003165	active site
235279003166	substrate binding site [chemical binding]; other site
235279003167	CoA binding site [chemical binding]; other site
235279003168	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
235279003169	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
235279003170	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
235279003171	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
235279003172	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
235279003173	Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. These are Mg++ dependent phosphatases. Members in this family may have fructose-1,6-bisphosphatase and/or inositol-monophosphatase activity. Fructose-1; Region: Arch_FBPase_2; cd01642
235279003174	putative active site [active]
235279003175	putative recombination protein RecO; Provisional; Region: PRK13908
235279003176	glutamate dehydrogenase; Provisional; Region: PRK09414
235279003177	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
235279003178	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
235279003179	NAD(P) binding site [chemical binding]; other site
235279003180	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
235279003181	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
235279003182	minor groove reading motif; other site
235279003183	helix-hairpin-helix signature motif; other site
235279003184	substrate binding pocket [chemical binding]; other site
235279003185	active site
235279003186	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
235279003187	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
235279003188	Putative NAD(P)-binding; Region: NAD_binding_7; cl17660
235279003189	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
235279003190	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
235279003191	DNA methylase; Region: N6_N4_Mtase; cl17433
235279003192	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
235279003193	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
235279003194	dimerization interface [polypeptide binding]; other site
235279003195	putative ATP binding site [chemical binding]; other site
235279003196	Bacterial SH3 domain; Region: SH3_3; pfam08239
235279003197	Bacterial SH3 domain; Region: SH3_3; pfam08239
235279003198	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
235279003199	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
235279003200	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
235279003201	shikimate binding site; other site
235279003202	NAD(P) binding site [chemical binding]; other site
235279003203	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
235279003204	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
235279003205	ligand binding site [chemical binding]; other site
235279003206	active site
235279003207	UGI interface [polypeptide binding]; other site
235279003208	catalytic site [active]
235279003209	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
235279003210	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
235279003211	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
235279003212	TrkA-N domain; Region: TrkA_N; pfam02254
235279003213	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
235279003214	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
235279003215	putative active site [active]
235279003216	putative metal binding site [ion binding]; other site
235279003217	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
235279003218	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
235279003219	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
235279003220	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
235279003221	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
235279003222	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
235279003223	Ligand Binding Site [chemical binding]; other site
235279003224	cbb3-type cytochrome c oxidase subunit I; Provisional; Region: PRK14488
235279003225	Low-spin heme binding site [chemical binding]; other site
235279003226	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
235279003227	D-pathway; other site
235279003228	Putative water exit pathway; other site
235279003229	Binuclear center (active site) [active]
235279003230	K-pathway; other site
235279003231	Putative proton exit pathway; other site
235279003232	cbb3-type cytochrome c oxidase subunit II; Provisional; Region: PRK14487
235279003233	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
235279003234	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
235279003235	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
235279003236	Cytochrome c; Region: Cytochrom_C; pfam00034
235279003237	Cytochrome c; Region: Cytochrom_C; pfam00034
235279003238	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
235279003239	Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]; Region: MRS6; COG5043
235279003240	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279003241	Major Facilitator Superfamily; Region: MFS_1; pfam07690
235279003242	putative substrate translocation pore; other site
235279003243	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
235279003244	FAD binding domain; Region: FAD_binding_4; pfam01565
235279003245	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
235279003246	META domain; Region: META; pfam03724
235279003247	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
235279003248	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
235279003249	active site
235279003250	PHP Thumb interface [polypeptide binding]; other site
235279003251	metal binding site [ion binding]; metal-binding site
235279003252	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
235279003253	generic binding surface I; other site
235279003254	generic binding surface II; other site
235279003255	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
235279003256	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279003257	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
235279003258	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
235279003259	NusA N-terminal domain; Region: NusA_N; pfam08529
235279003260	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
235279003261	RNA binding site [nucleotide binding]; other site
235279003262	homodimer interface [polypeptide binding]; other site
235279003263	NusA-like KH domain; Region: KH_5; pfam13184
235279003264	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
235279003265	G-X-X-G motif; other site
235279003266	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
235279003267	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
235279003268	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279003269	FeS/SAM binding site; other site
235279003270	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
235279003271	putative acyl-acceptor binding pocket; other site
235279003272	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
235279003273	MraW methylase family; Region: Methyltransf_5; cl17771
235279003274	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
235279003275	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
235279003276	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
235279003277	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
235279003278	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
235279003279	catalytic core [active]
235279003280	TIGR02757 family protein; Region: TIGR02757
235279003281	Outer membrane efflux protein; Region: OEP; pfam02321
235279003282	Outer membrane efflux protein; Region: OEP; pfam02321
235279003283	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
235279003284	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
235279003285	HlyD family secretion protein; Region: HlyD_3; pfam13437
235279003286	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
235279003287	Cation transport protein; Region: TrkH; cl17365
235279003288	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
235279003289	TrkA-N domain; Region: TrkA_N; pfam02254
235279003290	TrkA-C domain; Region: TrkA_C; pfam02080
235279003291	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
235279003292	heterotetramer interface [polypeptide binding]; other site
235279003293	active site pocket [active]
235279003294	cleavage site
235279003295	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
235279003296	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
235279003297	Domain of unknown function (DUF814); Region: DUF814; pfam05670
235279003298	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
235279003299	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
235279003300	Walker A/P-loop; other site
235279003301	ATP binding site [chemical binding]; other site
235279003302	Q-loop/lid; other site
235279003303	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
235279003304	ABC transporter signature motif; other site
235279003305	Walker B; other site
235279003306	D-loop; other site
235279003307	H-loop/switch region; other site
235279003308	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
235279003309	ATP-NAD kinase; Region: NAD_kinase; pfam01513
235279003310	putative inner membrane protein; Provisional; Region: PRK11099
235279003311	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
235279003312	CPxP  motif; other site
235279003313	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279003314	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
235279003315	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279003316	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
235279003317	HSP70 interaction site [polypeptide binding]; other site
235279003318	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
235279003319	Isochorismatase family; Region: Isochorismatase; pfam00857
235279003320	catalytic triad [active]
235279003321	conserved cis-peptide bond; other site
235279003322	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
235279003323	propionate/acetate kinase; Provisional; Region: PRK12379
235279003324	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
235279003325	Nitrate and nitrite sensing; Region: NIT; pfam08376
235279003326	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
235279003327	HAMP domain; Region: HAMP; pfam00672
235279003328	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279003329	dimer interface [polypeptide binding]; other site
235279003330	putative CheW interface [polypeptide binding]; other site
235279003331	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
235279003332	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
235279003333	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279003334	FeS/SAM binding site; other site
235279003335	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
235279003336	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
235279003337	NAD binding site [chemical binding]; other site
235279003338	homotetramer interface [polypeptide binding]; other site
235279003339	homodimer interface [polypeptide binding]; other site
235279003340	substrate binding site [chemical binding]; other site
235279003341	active site
235279003342	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
235279003343	triosephosphate isomerase; Provisional; Region: PRK14565
235279003344	substrate binding site [chemical binding]; other site
235279003345	dimer interface [polypeptide binding]; other site
235279003346	catalytic triad [active]
235279003347	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
235279003348	DNA polymerase I; Provisional; Region: PRK05755
235279003349	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
235279003350	active site
235279003351	metal binding site 1 [ion binding]; metal-binding site
235279003352	putative 5' ssDNA interaction site; other site
235279003353	metal binding site 3; metal-binding site
235279003354	metal binding site 2 [ion binding]; metal-binding site
235279003355	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
235279003356	putative DNA binding site [nucleotide binding]; other site
235279003357	putative metal binding site [ion binding]; other site
235279003358	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
235279003359	active site
235279003360	catalytic site [active]
235279003361	substrate binding site [chemical binding]; other site
235279003362	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
235279003363	active site
235279003364	DNA binding site [nucleotide binding]
235279003365	catalytic site [active]
235279003366	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
235279003367	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
235279003368	ABC-2 type transporter; Region: ABC2_membrane; cl17235
235279003369	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
235279003370	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
235279003371	Lumazine binding domain; Region: Lum_binding; pfam00677
235279003372	Lumazine binding domain; Region: Lum_binding; pfam00677
235279003373	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
235279003374	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
235279003375	active site
235279003376	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
235279003377	N-acetyl-D-glucosamine binding site [chemical binding]; other site
235279003378	catalytic residue [active]
235279003379	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
235279003380	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
235279003381	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
235279003382	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
235279003383	Sporulation related domain; Region: SPOR; pfam05036
235279003384	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
235279003385	putative active site pocket [active]
235279003386	4-fold oligomerization interface [polypeptide binding]; other site
235279003387	metal binding residues [ion binding]; metal-binding site
235279003388	3-fold/trimer interface [polypeptide binding]; other site
235279003389	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
235279003390	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
235279003391	active site
235279003392	motif I; other site
235279003393	motif II; other site
235279003394	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
235279003395	OstA-like protein; Region: OstA; pfam03968
235279003396	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
235279003397	G1 box; other site
235279003398	GTP/Mg2+ binding site [chemical binding]; other site
235279003399	Switch I region; other site
235279003400	G2 box; other site
235279003401	G3 box; other site
235279003402	Switch II region; other site
235279003403	G4 box; other site
235279003404	G5 box; other site
235279003405	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
235279003406	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
235279003407	Coenzyme A binding pocket [chemical binding]; other site
235279003408	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
235279003409	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
235279003410	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
235279003411	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
235279003412	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
235279003413	NAD(P) binding site [chemical binding]; other site
235279003414	homodimer interface [polypeptide binding]; other site
235279003415	substrate binding site [chemical binding]; other site
235279003416	active site
235279003417	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
235279003418	Ferritin-like domain; Region: Ferritin; pfam00210
235279003419	ferroxidase diiron center [ion binding]; other site
235279003420	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
235279003421	Flavoprotein; Region: Flavoprotein; pfam02441
235279003422	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
235279003423	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
235279003424	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
235279003425	dimer interface [polypeptide binding]; other site
235279003426	putative CheW interface [polypeptide binding]; other site
235279003427	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
235279003428	active site 2 [active]
235279003429	active site 1 [active]
235279003430	Methyltransferase domain; Region: Methyltransf_31; pfam13847
235279003431	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279003432	S-adenosylmethionine binding site [chemical binding]; other site
235279003433	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
235279003434	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
235279003435	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
235279003436	active site
235279003437	HIGH motif; other site
235279003438	KMSKS motif; other site
235279003439	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
235279003440	tRNA binding surface [nucleotide binding]; other site
235279003441	anticodon binding site; other site
235279003442	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
235279003443	dimer interface [polypeptide binding]; other site
235279003444	putative tRNA-binding site [nucleotide binding]; other site
235279003445	fructose-1,6-bisphosphatase; Provisional; Region: PRK09293
235279003446	active site
235279003447	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
235279003448	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
235279003449	substrate binding site [chemical binding]; other site
235279003450	hexamer interface [polypeptide binding]; other site
235279003451	metal binding site [ion binding]; metal-binding site
235279003452	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
235279003453	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
235279003454	active site
235279003455	catalytic site [active]
235279003456	substrate binding site [chemical binding]; other site
235279003457	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
235279003458	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279003459	S-adenosylmethionine binding site [chemical binding]; other site
235279003460	Peptidase family M48; Region: Peptidase_M48; pfam01435
235279003461	CTP synthetase; Validated; Region: pyrG; PRK05380
235279003462	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
235279003463	Catalytic site [active]
235279003464	active site
235279003465	UTP binding site [chemical binding]; other site
235279003466	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
235279003467	active site
235279003468	putative oxyanion hole; other site
235279003469	catalytic triad [active]
235279003470	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
235279003471	DHH family; Region: DHH; pfam01368
235279003472	DHHA1 domain; Region: DHHA1; pfam02272
235279003473	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
235279003474	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
235279003475	active site
235279003476	catalytic triad [active]
235279003477	dimer interface [polypeptide binding]; other site
235279003478	adenylosuccinate lyase; Provisional; Region: PRK08470
235279003479	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
235279003480	tetramer interface [polypeptide binding]; other site
235279003481	active site
235279003482	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
235279003483	RDD family; Region: RDD; pfam06271
235279003484	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
235279003485	active site
235279003486	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
235279003487	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
235279003488	Part of AAA domain; Region: AAA_19; pfam13245
235279003489	Family description; Region: UvrD_C_2; pfam13538
235279003490	SAF-like; Region: SAF_2; pfam13144
235279003491	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
235279003492	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
235279003493	Flavoprotein; Region: Flavoprotein; pfam02441
235279003494	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
235279003495	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
235279003496	active site
235279003497	(T/H)XGH motif; other site
235279003498	thymidylate kinase; Validated; Region: tmk; PRK00698
235279003499	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
235279003500	TMP-binding site; other site
235279003501	ATP-binding site [chemical binding]; other site
235279003502	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
235279003503	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
235279003504	active site
235279003505	flagellin A; Reviewed; Region: PRK12584
235279003506	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
235279003507	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
235279003508	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
235279003509	Cytochrome c; Region: Cytochrom_C; pfam00034
235279003510	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
235279003511	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
235279003512	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
235279003513	homodimer interface [polypeptide binding]; other site
235279003514	NADP binding site [chemical binding]; other site
235279003515	substrate binding site [chemical binding]; other site
235279003516	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
235279003517	Catalytic site [active]
235279003518	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
235279003519	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
235279003520	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
235279003521	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
235279003522	active site
235279003523	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
235279003524	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
235279003525	multifunctional aminopeptidase A; Provisional; Region: PRK00913
235279003526	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
235279003527	interface (dimer of trimers) [polypeptide binding]; other site
235279003528	Substrate-binding/catalytic site; other site
235279003529	Zn-binding sites [ion binding]; other site
235279003530	GTP-binding protein YchF; Reviewed; Region: PRK09601
235279003531	YchF GTPase; Region: YchF; cd01900
235279003532	G1 box; other site
235279003533	GTP/Mg2+ binding site [chemical binding]; other site
235279003534	Switch I region; other site
235279003535	G2 box; other site
235279003536	Switch II region; other site
235279003537	G3 box; other site
235279003538	G4 box; other site
235279003539	G5 box; other site
235279003540	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
235279003541	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279003542	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
235279003543	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
235279003544	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
235279003545	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
235279003546	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
235279003547	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
235279003548	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
235279003549	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
235279003550	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
235279003551	putative translocon binding site; other site
235279003552	protein-rRNA interface [nucleotide binding]; other site
235279003553	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
235279003554	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
235279003555	G-X-X-G motif; other site
235279003556	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
235279003557	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
235279003558	23S rRNA interface [nucleotide binding]; other site
235279003559	5S rRNA interface [nucleotide binding]; other site
235279003560	putative antibiotic binding site [chemical binding]; other site
235279003561	L25 interface [polypeptide binding]; other site
235279003562	L27 interface [polypeptide binding]; other site
235279003563	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
235279003564	putative translocon interaction site; other site
235279003565	23S rRNA interface [nucleotide binding]; other site
235279003566	signal recognition particle (SRP54) interaction site; other site
235279003567	L23 interface [polypeptide binding]; other site
235279003568	trigger factor interaction site; other site
235279003569	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
235279003570	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
235279003571	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
235279003572	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
235279003573	RNA binding site [nucleotide binding]; other site
235279003574	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
235279003575	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
235279003576	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
235279003577	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
235279003578	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
235279003579	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
235279003580	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
235279003581	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
235279003582	23S rRNA interface [nucleotide binding]; other site
235279003583	5S rRNA interface [nucleotide binding]; other site
235279003584	L27 interface [polypeptide binding]; other site
235279003585	L5 interface [polypeptide binding]; other site
235279003586	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
235279003587	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
235279003588	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
235279003589	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
235279003590	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
235279003591	SecY translocase; Region: SecY; pfam00344
235279003592	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
235279003593	active site
235279003594	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
235279003595	rRNA binding site [nucleotide binding]; other site
235279003596	predicted 30S ribosome binding site; other site
235279003597	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
235279003598	30S ribosomal protein S13; Region: bact_S13; TIGR03631
235279003599	30S ribosomal protein S11; Validated; Region: PRK05309
235279003600	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
235279003601	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
235279003602	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
235279003603	RNA binding surface [nucleotide binding]; other site
235279003604	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
235279003605	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
235279003606	alphaNTD homodimer interface [polypeptide binding]; other site
235279003607	alphaNTD - beta interaction site [polypeptide binding]; other site
235279003608	alphaNTD - beta' interaction site [polypeptide binding]; other site
235279003609	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
235279003610	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
235279003611	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
235279003612	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
235279003613	Domain of unknown function (DUF1910); Region: DUF1910; pfam08928
235279003614	Domain of unknown function (DUF1911); Region: DUF1911; pfam08929
235279003615	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
235279003616	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
235279003617	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
235279003618	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
235279003619	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
235279003620	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
235279003621	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
235279003622	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
235279003623	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
235279003624	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
235279003625	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
235279003626	substrate binding site [chemical binding]; other site
235279003627	active site
235279003628	catalytic residues [active]
235279003629	heterodimer interface [polypeptide binding]; other site
235279003630	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
235279003631	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
235279003632	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279003633	catalytic residue [active]
235279003634	methionine sulfoxide reductase B; Provisional; Region: PRK05508
235279003635	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
235279003636	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
235279003637	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
235279003638	DEAD-like helicases superfamily; Region: DEXDc; smart00487
235279003639	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279003640	ATP binding site [chemical binding]; other site
235279003641	putative Mg++ binding site [ion binding]; other site
235279003642	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
235279003643	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
235279003644	Domain of unknown function (DUF1837); Region: DUF1837; pfam08878
235279003645	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279003646	ATP binding site [chemical binding]; other site
235279003647	putative Mg++ binding site [ion binding]; other site
235279003648	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
235279003649	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
235279003650	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
235279003651	Fic family protein [Function unknown]; Region: COG3177
235279003652	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
235279003653	Fic/DOC family; Region: Fic; pfam02661
235279003654	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
235279003655	HsdM N-terminal domain; Region: HsdM_N; pfam12161
235279003656	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
235279003657	Methyltransferase domain; Region: Methyltransf_26; pfam13659
235279003658	arsenical pump membrane protein; Provisional; Region: PRK15445
235279003659	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
235279003660	transmembrane helices; other site
235279003661	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
235279003662	Methyltransferase domain; Region: Methyltransf_23; pfam13489
235279003663	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279003664	S-adenosylmethionine binding site [chemical binding]; other site
235279003665	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
235279003666	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279003667	S-adenosylmethionine binding site [chemical binding]; other site
235279003668	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
235279003669	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
235279003670	hypothetical protein; Provisional; Region: PHA02695; cl17648
235279003671	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
235279003672	Methyltransferase domain; Region: Methyltransf_31; pfam13847
235279003673	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279003674	S-adenosylmethionine binding site [chemical binding]; other site
235279003675	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
235279003676	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
235279003677	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
235279003678	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
235279003679	hypothetical protein; Provisional; Region: PRK05849
235279003680	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
235279003681	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
235279003682	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
235279003683	catalytic triad [active]
235279003684	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
235279003685	AAA domain; Region: AAA_18; pfam13238
235279003686	ligand-binding site [chemical binding]; other site
235279003687	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
235279003688	active site
235279003689	metal-binding site
235279003690	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
235279003691	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
235279003692	active site
235279003693	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
235279003694	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
235279003695	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
235279003696	conserved cys residue [active]
235279003697	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
235279003698	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
235279003699	Coenzyme A binding pocket [chemical binding]; other site
235279003700	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
235279003701	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
235279003702	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
235279003703	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
235279003704	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
235279003705	Coenzyme A binding pocket [chemical binding]; other site
235279003706	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
235279003707	GMP synthase, PP-ATPase domain/subunit [Nucleotide transport and metabolism]; Region: GuaA; COG0519
235279003708	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
235279003709	ATP Binding subdomain [chemical binding]; other site
235279003710	Ligand Binding sites [chemical binding]; other site
235279003711	Dimerization subdomain; other site
235279003712	DNA methylase; Region: N6_N4_Mtase; cl17433
235279003713	Cytolethal distending toxin A/C family; Region: CDtoxinA; pfam03498
235279003714	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
235279003715	putative sugar binding sites [chemical binding]; other site
235279003716	Q-X-W motif; other site
235279003717	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
235279003718	putative catalytic site [active]
235279003719	CdtC interface [polypeptide binding]; other site
235279003720	heterotrimer interface [polypeptide binding]; other site
235279003721	CdtA interface [polypeptide binding]; other site
235279003722	putative metal binding site [ion binding]; other site
235279003723	putative phosphate binding site [ion binding]; other site
235279003724	Cytolethal distending toxin A/C family; Region: CDtoxinA; pfam03498
235279003725	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
235279003726	NADH(P)-binding; Region: NAD_binding_10; pfam13460
235279003727	DinB family; Region: DinB; cl17821
235279003728	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
235279003729	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
235279003730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279003731	Major Facilitator Superfamily; Region: MFS_1; pfam07690
235279003732	putative substrate translocation pore; other site
235279003733	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
235279003734	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
235279003735	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
235279003736	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
235279003737	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
235279003738	active site
235279003739	catalytic tetrad [active]
235279003740	Predicted transcriptional regulator [Transcription]; Region: COG1959
235279003741	Transcriptional regulator; Region: Rrf2; pfam02082
235279003742	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
235279003743	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279003744	putative substrate translocation pore; other site
235279003745	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
235279003746	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
235279003747	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
235279003748	maltose O-acetyltransferase; Provisional; Region: PRK10092
235279003749	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
235279003750	active site
235279003751	substrate binding site [chemical binding]; other site
235279003752	trimer interface [polypeptide binding]; other site
235279003753	CoA binding site [chemical binding]; other site
235279003754	Protein of unknown function (DUF1561); Region: DUF1561; pfam07598
235279003755	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
235279003756	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
235279003757	active site
235279003758	catalytic tetrad [active]
235279003759	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
235279003760	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
235279003761	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
235279003762	NADH(P)-binding; Region: NAD_binding_10; pfam13460
235279003763	putative NAD(P) binding site [chemical binding]; other site
235279003764	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; cl17869
235279003765	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
235279003766	gating phenylalanine in ion channel; other site
235279003767	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
235279003768	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
235279003769	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
235279003770	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
235279003771	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
235279003772	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
235279003773	Walker A/P-loop; other site
235279003774	ATP binding site [chemical binding]; other site
235279003775	Q-loop/lid; other site
235279003776	ABC transporter signature motif; other site
235279003777	Walker B; other site
235279003778	D-loop; other site
235279003779	H-loop/switch region; other site
235279003780	bifunctional adhesin/ABC transporter aspartate/glutamate-binding protein; Reviewed; Region: PRK11917
235279003781	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
235279003782	substrate binding pocket [chemical binding]; other site
235279003783	membrane-bound complex binding site; other site
235279003784	hinge residues; other site
235279003785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279003786	dimer interface [polypeptide binding]; other site
235279003787	conserved gate region; other site
235279003788	putative PBP binding loops; other site
235279003789	ABC-ATPase subunit interface; other site
235279003790	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
235279003791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279003792	dimer interface [polypeptide binding]; other site
235279003793	conserved gate region; other site
235279003794	putative PBP binding loops; other site
235279003795	ABC-ATPase subunit interface; other site
235279003796	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
235279003797	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279003798	S-adenosylmethionine binding site [chemical binding]; other site
235279003799	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
235279003800	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
235279003801	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
235279003802	sec-independent translocase; Provisional; Region: PRK04098
235279003803	seryl-tRNA synthetase; Provisional; Region: PRK05431
235279003804	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
235279003805	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
235279003806	dimer interface [polypeptide binding]; other site
235279003807	active site
235279003808	motif 1; other site
235279003809	motif 2; other site
235279003810	motif 3; other site
235279003811	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
235279003812	binding surface
235279003813	TPR motif; other site
235279003814	type II citrate synthase; Reviewed; Region: gltA; PRK05614
235279003815	Citrate synthase; Region: Citrate_synt; pfam00285
235279003816	oxalacetate binding site [chemical binding]; other site
235279003817	citrylCoA binding site [chemical binding]; other site
235279003818	coenzyme A binding site [chemical binding]; other site
235279003819	catalytic triad [active]
235279003820	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
235279003821	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
235279003822	5S rRNA interface [nucleotide binding]; other site
235279003823	CTC domain interface [polypeptide binding]; other site
235279003824	L16 interface [polypeptide binding]; other site
235279003825	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
235279003826	putative active site [active]
235279003827	catalytic residue [active]
235279003828	Predicted permeases [General function prediction only]; Region: COG0795
235279003829	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
235279003830	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
235279003831	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
235279003832	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
235279003833	thiamine phosphate binding site [chemical binding]; other site
235279003834	pyrophosphate binding site [ion binding]; other site
235279003835	active site
235279003836	Sulfatase; Region: Sulfatase; cl17466
235279003837	EamA-like transporter family; Region: EamA; pfam00892
235279003838	TRL-like protein family; Region: TRL; pfam13146
235279003839	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
235279003840	Putative catalytic NodB homology domain of uncharacterized BH0857 protein from Bacillus halodurans and its bacterial homologs; Region: CE4_BH0857_like; cd10955
235279003841	NodB motif; other site
235279003842	putative active site [active]
235279003843	putative catalytic site [active]
235279003844	Na/Pi-cotransporter; Region: NaPi_cotrn_rel; TIGR00704
235279003845	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
235279003846	Predicted permeases [General function prediction only]; Region: COG0679
235279003847	antiporter inner membrane protein; Provisional; Region: PRK11670
235279003848	Domain of unknown function DUF59; Region: DUF59; pfam01883
235279003849	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
235279003850	diaminopimelate decarboxylase; Region: lysA; TIGR01048
235279003851	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
235279003852	active site
235279003853	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
235279003854	substrate binding site [chemical binding]; other site
235279003855	catalytic residues [active]
235279003856	dimer interface [polypeptide binding]; other site
235279003857	Chorismate mutase type II; Region: CM_2; smart00830
235279003858	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
235279003859	Prephenate dehydratase; Region: PDT; pfam00800
235279003860	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
235279003861	putative L-Phe binding site [chemical binding]; other site
235279003862	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
235279003863	Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis...; Region: GH25_muramidase_1; cd06413
235279003864	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
235279003865	active site
235279003866	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
235279003867	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
235279003868	PGAP1-like protein; Region: PGAP1; pfam07819
235279003869	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
235279003870	dinuclear metal binding motif [ion binding]; other site
235279003871	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
235279003872	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
235279003873	active site
235279003874	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
235279003875	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
235279003876	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
235279003877	Permutation of conserved domain; other site
235279003878	active site
235279003879	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
235279003880	alanine racemase; Reviewed; Region: alr; PRK00053
235279003881	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
235279003882	catalytic residue [active]
235279003883	Cytochrome c; Region: Cytochrom_C; cl11414
235279003884	recombination protein RecR; Reviewed; Region: recR; PRK00076
235279003885	RecR protein; Region: RecR; pfam02132
235279003886	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
235279003887	putative active site [active]
235279003888	putative metal-binding site [ion binding]; other site
235279003889	tetramer interface [polypeptide binding]; other site
235279003890	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
235279003891	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
235279003892	HSP70 interaction site [polypeptide binding]; other site
235279003893	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
235279003894	Zn binding sites [ion binding]; other site
235279003895	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
235279003896	dimer interface [polypeptide binding]; other site
235279003897	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
235279003898	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
235279003899	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
235279003900	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
235279003901	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
235279003902	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
235279003903	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
235279003904	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
235279003905	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
235279003906	dimer interface [polypeptide binding]; other site
235279003907	active site
235279003908	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
235279003909	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
235279003910	putative ribose interaction site [chemical binding]; other site
235279003911	putative ADP binding site [chemical binding]; other site
235279003912	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
235279003913	active site
235279003914	HIGH motif; other site
235279003915	nucleotide binding site [chemical binding]; other site
235279003916	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
235279003917	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
235279003918	NAD(P) binding site [chemical binding]; other site
235279003919	active site
235279003920	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
235279003921	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
235279003922	active site
235279003923	motif I; other site
235279003924	motif II; other site
235279003925	Family description; Region: DsbD_2; pfam13386
235279003926	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
235279003927	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
235279003928	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
235279003929	active site
235279003930	GTP-binding protein Der; Reviewed; Region: PRK00093
235279003931	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
235279003932	G1 box; other site
235279003933	GTP/Mg2+ binding site [chemical binding]; other site
235279003934	Switch I region; other site
235279003935	G2 box; other site
235279003936	Switch II region; other site
235279003937	G3 box; other site
235279003938	G4 box; other site
235279003939	G5 box; other site
235279003940	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
235279003941	G1 box; other site
235279003942	GTP/Mg2+ binding site [chemical binding]; other site
235279003943	Switch I region; other site
235279003944	G2 box; other site
235279003945	G3 box; other site
235279003946	Switch II region; other site
235279003947	G4 box; other site
235279003948	G5 box; other site
235279003949	S-adenosylmethionine synthetase; Validated; Region: PRK05250
235279003950	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
235279003951	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
235279003952	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
235279003953	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
235279003954	TonB-dependent copper receptor; Region: TonB-copper; TIGR01778
235279003955	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279003956	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
235279003957	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
235279003958	dimer interface [polypeptide binding]; other site
235279003959	decamer (pentamer of dimers) interface [polypeptide binding]; other site
235279003960	catalytic triad [active]
235279003961	peroxidatic and resolving cysteines [active]
235279003962	Protein of unknown function, DUF485; Region: DUF485; pfam04341
235279003963	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
235279003964	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
235279003965	Na binding site [ion binding]; other site
235279003966	excinuclease ABC subunit B; Provisional; Region: PRK05298
235279003967	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279003968	ATP binding site [chemical binding]; other site
235279003969	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
235279003970	nucleotide binding region [chemical binding]; other site
235279003971	ATP-binding site [chemical binding]; other site
235279003972	Ultra-violet resistance protein B; Region: UvrB; pfam12344
235279003973	UvrB/uvrC motif; Region: UVR; pfam02151
235279003974	primosome assembly protein PriA; Validated; Region: PRK05580
235279003975	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
235279003976	ATP binding site [chemical binding]; other site
235279003977	putative Mg++ binding site [ion binding]; other site
235279003978	helicase superfamily c-terminal domain; Region: HELICc; smart00490
235279003979	ATP-binding site [chemical binding]; other site
235279003980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
235279003981	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
235279003982	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
235279003983	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
235279003984	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
235279003985	malonic semialdehyde reductase; Provisional; Region: PRK10538
235279003986	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
235279003987	putative NAD(P) binding site [chemical binding]; other site
235279003988	homodimer interface [polypeptide binding]; other site
235279003989	homotetramer interface [polypeptide binding]; other site
235279003990	active site
235279003991	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
235279003992	S1 domain; Region: S1_2; pfam13509
235279003993	S1 domain; Region: S1_2; pfam13509
235279003994	Domain of unknown function (DUF305); Region: DUF305; pfam03713
235279003995	Protein of unknown function (DUF815); Region: DUF815; pfam05673
235279003996	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
235279003997	Clp amino terminal domain; Region: Clp_N; pfam02861
235279003998	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279003999	Walker A motif; other site
235279004000	ATP binding site [chemical binding]; other site
235279004001	Walker B motif; other site
235279004002	arginine finger; other site
235279004003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279004004	Walker A motif; other site
235279004005	ATP binding site [chemical binding]; other site
235279004006	Walker B motif; other site
235279004007	arginine finger; other site
235279004008	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
235279004009	Uncharacterized conserved protein [Function unknown]; Region: COG2127
235279004010	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
235279004011	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
235279004012	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
235279004013	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
235279004014	TPP-binding site [chemical binding]; other site
235279004015	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
235279004016	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
235279004017	dimer interface [polypeptide binding]; other site
235279004018	PYR/PP interface [polypeptide binding]; other site
235279004019	TPP binding site [chemical binding]; other site
235279004020	substrate binding site [chemical binding]; other site
235279004021	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
235279004022	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
235279004023	malate dehydrogenase; Reviewed; Region: PRK06223
235279004024	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
235279004025	NAD(P) binding site [chemical binding]; other site
235279004026	dimer interface [polypeptide binding]; other site
235279004027	tetramer (dimer of dimers) interface [polypeptide binding]; other site
235279004028	substrate binding site [chemical binding]; other site
235279004029	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
235279004030	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
235279004031	dimerization interface [polypeptide binding]; other site
235279004032	Protein of unknown function; Region: DUF3971; pfam13116
235279004033	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
235279004034	FeoA domain; Region: FeoA; pfam04023
235279004035	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
235279004036	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
235279004037	minor groove reading motif; other site
235279004038	helix-hairpin-helix signature motif; other site
235279004039	substrate binding pocket [chemical binding]; other site
235279004040	active site
235279004041	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
235279004042	flagellar motor switch protein; Validated; Region: PRK08433
235279004043	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
235279004044	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
235279004045	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
235279004046	YCII-related domain; Region: YCII; cl00999
235279004047	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
235279004048	ThiC family; Region: ThiC; pfam01964
235279004049	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
235279004050	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
235279004051	substrate binding site; other site
235279004052	dimer interface; other site
235279004053	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
235279004054	homotrimer interaction site [polypeptide binding]; other site
235279004055	zinc binding site [ion binding]; other site
235279004056	CDP-binding sites; other site
235279004057	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
235279004058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279004059	active site
235279004060	phosphorylation site [posttranslational modification]
235279004061	intermolecular recognition site; other site
235279004062	dimerization interface [polypeptide binding]; other site
235279004063	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
235279004064	tetramer interfaces [polypeptide binding]; other site
235279004065	binuclear metal-binding site [ion binding]; other site
235279004066	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
235279004067	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
235279004068	ATP binding site [chemical binding]; other site
235279004069	substrate interface [chemical binding]; other site
235279004070	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
235279004071	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00144
235279004072	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
235279004073	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
235279004074	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
235279004075	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
235279004076	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
235279004077	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
235279004078	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
235279004079	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
235279004080	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
235279004081	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
235279004082	4Fe-4S binding domain; Region: Fer4; cl02805
235279004083	4Fe-4S binding domain; Region: Fer4; pfam00037
235279004084	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
235279004085	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
235279004086	NADH dehydrogenase subunit G; Validated; Region: PRK08493
235279004087	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
235279004088	catalytic loop [active]
235279004089	iron binding site [ion binding]; other site
235279004090	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
235279004091	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
235279004092	NADH dehydrogenase subunit G; Validated; Region: PRK08493
235279004093	NADH dehydrogenase subunit D; Validated; Region: PRK06075
235279004094	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
235279004095	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
235279004096	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
235279004097	NADH dehydrogenase subunit B; Validated; Region: PRK06411
235279004098	NADH dehydrogenase subunit A; Validated; Region: PRK08489
235279004099	hypothetical protein; Provisional; Region: PRK12378
235279004100	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
235279004101	dimer interface [polypeptide binding]; other site
235279004102	active site
235279004103	Schiff base residues; other site
235279004104	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
235279004105	HAMP domain; Region: HAMP; pfam00672
235279004106	dimerization interface [polypeptide binding]; other site
235279004107	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279004108	ATP binding site [chemical binding]; other site
235279004109	Mg2+ binding site [ion binding]; other site
235279004110	G-X-G motif; other site
235279004111	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
235279004112	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279004113	active site
235279004114	phosphorylation site [posttranslational modification]
235279004115	intermolecular recognition site; other site
235279004116	dimerization interface [polypeptide binding]; other site
235279004117	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
235279004118	DNA binding site [nucleotide binding]
235279004119	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
235279004120	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
235279004121	Ligand Binding Site [chemical binding]; other site
235279004122	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
235279004123	Major Facilitator Superfamily; Region: MFS_1; pfam07690
235279004124	putative substrate translocation pore; other site
235279004125	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
235279004126	active site
235279004127	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
235279004128	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
235279004129	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
235279004130	protein binding site [polypeptide binding]; other site
235279004131	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
235279004132	Catalytic dyad [active]
235279004133	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
235279004134	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
235279004135	ATP binding site [chemical binding]; other site
235279004136	active site
235279004137	substrate binding site [chemical binding]; other site
235279004138	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
235279004139	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
235279004140	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
235279004141	putative active site [active]
235279004142	catalytic triad [active]
235279004143	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
235279004144	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
235279004145	putative acyl-acceptor binding pocket; other site
235279004146	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
235279004147	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
235279004148	quinone interaction residues [chemical binding]; other site
235279004149	active site
235279004150	catalytic residues [active]
235279004151	FMN binding site [chemical binding]; other site
235279004152	substrate binding site [chemical binding]; other site
235279004153	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
235279004154	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
235279004155	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
235279004156	dihydrodipicolinate synthase; Region: dapA; TIGR00674
235279004157	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
235279004158	dimer interface [polypeptide binding]; other site
235279004159	active site
235279004160	catalytic residue [active]
235279004161	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
235279004162	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
235279004163	putative NAD(P) binding site [chemical binding]; other site
235279004164	active site
235279004165	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
235279004166	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
235279004167	active site
235279004168	catalytic triad [active]
235279004169	TPR repeat; Region: TPR_11; pfam13414
235279004170	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
235279004171	binding surface
235279004172	TPR motif; other site
235279004173	TPR repeat; Region: TPR_11; pfam13414
235279004174	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
235279004175	binding surface
235279004176	TPR motif; other site
235279004177	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
235279004178	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
235279004179	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
235279004180	DNA gyrase subunit A; Validated; Region: PRK05560
235279004181	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
235279004182	CAP-like domain; other site
235279004183	active site
235279004184	primary dimer interface [polypeptide binding]; other site
235279004185	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
235279004186	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
235279004187	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
235279004188	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
235279004189	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
235279004190	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
235279004191	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
235279004192	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279004193	active site
235279004194	phosphorylation site [posttranslational modification]
235279004195	intermolecular recognition site; other site
235279004196	dimerization interface [polypeptide binding]; other site
235279004197	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279004198	Walker A motif; other site
235279004199	ATP binding site [chemical binding]; other site
235279004200	Walker B motif; other site
235279004201	arginine finger; other site
235279004202	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
235279004203	Domain of unknown function DUF21; Region: DUF21; pfam01595
235279004204	FOG: CBS domain [General function prediction only]; Region: COG0517
235279004205	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
235279004206	Domain of unknown function DUF21; Region: DUF21; pfam01595
235279004207	FOG: CBS domain [General function prediction only]; Region: COG0517
235279004208	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
235279004209	recombination factor protein RarA; Reviewed; Region: PRK13342
235279004210	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
235279004211	Walker A motif; other site
235279004212	ATP binding site [chemical binding]; other site
235279004213	Walker B motif; other site
235279004214	arginine finger; other site
235279004215	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
235279004216	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
235279004217	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
235279004218	DNA binding residues [nucleotide binding]
235279004219	putative dimer interface [polypeptide binding]; other site
235279004220	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
235279004221	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
235279004222	HSP70 interaction site [polypeptide binding]; other site
235279004223	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
235279004224	substrate binding site [polypeptide binding]; other site
235279004225	dimer interface [polypeptide binding]; other site
235279004226	putative recombination protein RecB; Provisional; Region: PRK13909
235279004227	Family description; Region: UvrD_C_2; pfam13538
235279004228	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
235279004229	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
235279004230	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
235279004231	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
235279004232	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
235279004233	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
235279004234	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
235279004235	Protein export membrane protein; Region: SecD_SecF; pfam02355
235279004236	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
235279004237	flagellin A; Reviewed; Region: PRK12584
235279004238	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
235279004239	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
235279004240	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
235279004241	hypothetical protein; Provisional; Region: PRK10621
235279004242	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
235279004243	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
235279004244	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
235279004245	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279004246	active site
235279004247	phosphorylation site [posttranslational modification]
235279004248	intermolecular recognition site; other site
235279004249	dimerization interface [polypeptide binding]; other site
235279004250	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
235279004251	DNA binding site [nucleotide binding]
235279004252	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
235279004253	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
235279004254	dimer interface [polypeptide binding]; other site
235279004255	phosphorylation site [posttranslational modification]
235279004256	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279004257	ATP binding site [chemical binding]; other site
235279004258	Mg2+ binding site [ion binding]; other site
235279004259	G-X-G motif; other site
235279004260	replicative DNA helicase; Provisional; Region: PRK08506
235279004261	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
235279004262	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
235279004263	Walker A motif; other site
235279004264	ATP binding site [chemical binding]; other site
235279004265	Walker B motif; other site
235279004266	DNA binding loops [nucleotide binding]
235279004267	Competence protein; Region: Competence; pfam03772
235279004268	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
235279004269	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
235279004270	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
235279004271	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
235279004272	putative trimer interface [polypeptide binding]; other site
235279004273	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
235279004274	putative CoA binding site [chemical binding]; other site
235279004275	putative trimer interface [polypeptide binding]; other site
235279004276	putative active site [active]
235279004277	putative substrate binding site [chemical binding]; other site
235279004278	putative CoA binding site [chemical binding]; other site
235279004279	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
235279004280	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
235279004281	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
235279004282	Sporulation related domain; Region: SPOR; pfam05036
235279004283	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
235279004284	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
235279004285	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
235279004286	dimer interface [polypeptide binding]; other site
235279004287	active site
235279004288	glycine-pyridoxal phosphate binding site [chemical binding]; other site
235279004289	folate binding site [chemical binding]; other site
235279004290	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
235279004291	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
235279004292	dimer interface [polypeptide binding]; other site
235279004293	putative anticodon binding site; other site
235279004294	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
235279004295	motif 1; other site
235279004296	active site
235279004297	motif 2; other site
235279004298	motif 3; other site
235279004299	Colicin V production protein; Region: Colicin_V; pfam02674
235279004300	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
235279004301	prenyltransferase; Reviewed; Region: ubiA; PRK12874
235279004302	UbiA prenyltransferase family; Region: UbiA; pfam01040
235279004303	aspartate aminotransferase; Provisional; Region: PRK05764
235279004304	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
235279004305	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279004306	homodimer interface [polypeptide binding]; other site
235279004307	catalytic residue [active]
235279004308	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
235279004309	BNR repeat-like domain; Region: BNR_2; pfam13088
235279004310	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
235279004311	Sulfatase; Region: Sulfatase; cl17466
235279004312	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
235279004313	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279004314	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
235279004315	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
235279004316	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
235279004317	oligomer interface [polypeptide binding]; other site
235279004318	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
235279004319	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
235279004320	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
235279004321	active site
235279004322	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
235279004323	protein binding site [polypeptide binding]; other site
235279004324	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
235279004325	putative substrate binding region [chemical binding]; other site
235279004326	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
235279004327	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
235279004328	catalytic residue [active]
235279004329	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
235279004330	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
235279004331	Protein of unknown function (DUF328); Region: DUF328; pfam03883
235279004332	pyruvate carboxylase subunit B; Validated; Region: PRK09282
235279004333	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
235279004334	active site
235279004335	catalytic residues [active]
235279004336	metal binding site [ion binding]; metal-binding site
235279004337	homodimer binding site [polypeptide binding]; other site
235279004338	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
235279004339	carboxyltransferase (CT) interaction site; other site
235279004340	biotinylation site [posttranslational modification]; other site
235279004341	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
235279004342	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
235279004343	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
235279004344	catalytic residue [active]
235279004345	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
235279004346	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
235279004347	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
235279004348	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
235279004349	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
235279004350	ATP-grasp domain; Region: ATP-grasp_4; cl17255
235279004351	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
235279004352	IMP binding site; other site
235279004353	dimer interface [polypeptide binding]; other site
235279004354	interdomain contacts; other site
235279004355	partial ornithine binding site; other site
235279004356	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
235279004357	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
235279004358	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
235279004359	putative active site [active]
235279004360	putative substrate binding site [chemical binding]; other site
235279004361	putative cosubstrate binding site; other site
235279004362	catalytic site [active]
235279004363	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
235279004364	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
235279004365	oligomer interface [polypeptide binding]; other site
235279004366	tandem repeat interface [polypeptide binding]; other site
235279004367	active site residues [active]
235279004368	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
235279004369	homotrimer interaction site [polypeptide binding]; other site
235279004370	putative active site [active]
235279004371	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
235279004372	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
235279004373	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
235279004374	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
235279004375	putative active site [active]
235279004376	putative metal binding site [ion binding]; other site
235279004377	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
235279004378	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279004379	active site
235279004380	phosphorylation site [posttranslational modification]
235279004381	intermolecular recognition site; other site
235279004382	dimerization interface [polypeptide binding]; other site
235279004383	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
235279004384	DNA binding site [nucleotide binding]
235279004385	spermidine synthase; Provisional; Region: speE; PRK00536
235279004386	spermidine synthase; Provisional; Region: PRK00811
235279004387	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
235279004388	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
235279004389	CoA-binding site [chemical binding]; other site
235279004390	ATP-binding [chemical binding]; other site
235279004391	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
235279004392	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
235279004393	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
235279004394	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
235279004395	RNA binding surface [nucleotide binding]; other site
235279004396	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
235279004397	flagellar hook protein FlgE, epsilon proteobacterial; Region: flgE_epsilon; TIGR02489
235279004398	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
235279004399	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
235279004400	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
235279004401	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
235279004402	Protein of unknown function (DUF2860); Region: DUF2860; pfam11059
235279004403	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
235279004404	putative oxidoreductase; Provisional; Region: PRK11445
235279004405	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
235279004406	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
235279004407	active site
235279004408	NTP binding site [chemical binding]; other site
235279004409	metal binding triad [ion binding]; metal-binding site
235279004410	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
235279004411	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
235279004412	heat shock protein HtpX; Provisional; Region: PRK02870
235279004413	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
235279004414	GTP cyclohydrolase I; Provisional; Region: PLN03044
235279004415	active site
235279004416	histidinol-phosphatase; Provisional; Region: PRK07328
235279004417	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
235279004418	active site
235279004419	dimer interface [polypeptide binding]; other site
235279004420	META domain; Region: META; pfam03724
235279004421	Uncharacterized conserved protein [Function unknown]; Region: COG1739
235279004422	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
235279004423	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
235279004424	argininosuccinate lyase; Provisional; Region: PRK00855
235279004425	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
235279004426	active sites [active]
235279004427	tetramer interface [polypeptide binding]; other site
235279004428	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
235279004429	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279004430	S-adenosylmethionine binding site [chemical binding]; other site
235279004431	malate:quinone oxidoreductase; Validated; Region: PRK05257
235279004432	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
235279004433	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
235279004434	histidinol dehydrogenase; Region: hisD; TIGR00069
235279004435	NAD binding site [chemical binding]; other site
235279004436	dimerization interface [polypeptide binding]; other site
235279004437	product binding site; other site
235279004438	substrate binding site [chemical binding]; other site
235279004439	zinc binding site [ion binding]; other site
235279004440	catalytic residues [active]
235279004441	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
235279004442	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
235279004443	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
235279004444	substrate binding pocket [chemical binding]; other site
235279004445	chain length determination region; other site
235279004446	substrate-Mg2+ binding site; other site
235279004447	catalytic residues [active]
235279004448	aspartate-rich region 1; other site
235279004449	active site lid residues [active]
235279004450	aspartate-rich region 2; other site
235279004451	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
235279004452	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
235279004453	tRNA; other site
235279004454	putative tRNA binding site [nucleotide binding]; other site
235279004455	putative NADP binding site [chemical binding]; other site
235279004456	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
235279004457	prolyl-tRNA synthetase; Provisional; Region: PRK09194
235279004458	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
235279004459	dimer interface [polypeptide binding]; other site
235279004460	motif 1; other site
235279004461	active site
235279004462	motif 2; other site
235279004463	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
235279004464	putative deacylase active site [active]
235279004465	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
235279004466	active site
235279004467	motif 3; other site
235279004468	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
235279004469	anticodon binding site; other site
235279004470	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
235279004471	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
235279004472	domain interfaces; other site
235279004473	active site
235279004474	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279004475	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
235279004476	biotin synthase; Provisional; Region: PRK08508
235279004477	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
235279004478	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
235279004479	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
235279004480	generic binding surface II; other site
235279004481	generic binding surface I; other site
235279004482	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
235279004483	dimerization interface [polypeptide binding]; other site
235279004484	putative ATP binding site [chemical binding]; other site
235279004485	SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain.  The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY,  and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421
235279004486	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
235279004487	CPxP  motif; other site
235279004488	DsrE/DsrF-like family; Region: DrsE; pfam02635
235279004489	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
235279004490	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
235279004491	substrate binding site [chemical binding]; other site
235279004492	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
235279004493	substrate binding site [chemical binding]; other site
235279004494	ligand binding site [chemical binding]; other site
235279004495	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
235279004496	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
235279004497	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
235279004498	catalytic residue [active]
235279004499	heat shock protein 90; Provisional; Region: PRK05218
235279004500	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
235279004501	ATP binding site [chemical binding]; other site
235279004502	Mg2+ binding site [ion binding]; other site
235279004503	G-X-G motif; other site
235279004504	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279004505	FeS/SAM binding site; other site
235279004506	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
235279004507	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
235279004508	Predicted methyltransferases [General function prediction only]; Region: COG0313
235279004509	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
235279004510	putative SAM binding site [chemical binding]; other site
235279004511	putative homodimer interface [polypeptide binding]; other site
235279004512	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
235279004513	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
235279004514	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
235279004515	aspartate aminotransferase; Provisional; Region: PRK08636
235279004516	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
235279004517	pyridoxal 5'-phosphate binding site [chemical binding]; other site
235279004518	homodimer interface [polypeptide binding]; other site
235279004519	catalytic residue [active]
235279004520	homoserine dehydrogenase; Provisional; Region: PRK06349
235279004521	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
235279004522	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
235279004523	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
235279004524	hypothetical protein; Reviewed; Region: PRK12497
235279004525	IncFII RepA protein family; Region: IncFII_repA; cl11495
235279004526	Predicted kinase [General function prediction only]; Region: COG4639
235279004527	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
235279004528	active site
235279004529	metal binding site [ion binding]; metal-binding site
235279004530	RNA ligase; Region: RNA_lig_T4_1; pfam09511
235279004531	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
235279004532	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
235279004533	ABC-ATPase subunit  interface; other site
235279004534	dimer interface [polypeptide binding]; other site
235279004535	putative PBP binding regions; other site
235279004536	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
235279004537	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
235279004538	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
235279004539	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
235279004540	intersubunit interface [polypeptide binding]; other site
235279004541	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
235279004542	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
235279004543	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
235279004544	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
235279004545	NlpC/P60 family; Region: NLPC_P60; cl17555
235279004546	Arsenate Reductase (ArsC) family; composed of TRX-fold arsenic reductases and similar proteins including the transcriptional regulator, Spx. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from...; Region: ArsC_family; cd02977
235279004547	ArsC family; Region: ArsC; pfam03960
235279004548	catalytic residue [active]
235279004549	Low molecular weight phosphatase family; Region: LMWPc; cd00115
235279004550	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
235279004551	active site
235279004552	chlorohydrolase; Provisional; Region: PRK08418
235279004553	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
235279004554	active site
235279004555	Mechanosensitive ion channel; Region: MS_channel; pfam00924
235279004556	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
235279004557	dihydroorotase; Provisional; Region: PRK08417
235279004558	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
235279004559	active site
235279004560	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
235279004561	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
235279004562	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
235279004563	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
235279004564	ATP binding site [chemical binding]; other site
235279004565	Mg++ binding site [ion binding]; other site
235279004566	motif III; other site
235279004567	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
235279004568	nucleotide binding region [chemical binding]; other site
235279004569	ATP-binding site [chemical binding]; other site
235279004570	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
235279004571	adenylate kinase; Reviewed; Region: adk; PRK00279
235279004572	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
235279004573	AMP-binding site [chemical binding]; other site
235279004574	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
235279004575	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
235279004576	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
235279004577	Switch I region; other site
235279004578	G2 box; other site
235279004579	putative GEF interaction site [polypeptide binding]; other site
235279004580	G3 box; other site
235279004581	Switch II region; other site
235279004582	GTP/Mg2+ binding site [chemical binding]; other site
235279004583	G4 box; other site
235279004584	G5 box; other site
235279004585	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
235279004586	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
235279004587	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
235279004588	dimer interface [polypeptide binding]; other site
235279004589	FMN binding site [chemical binding]; other site
235279004590	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
235279004591	ATP cone domain; Region: ATP-cone; pfam03477
235279004592	Class I ribonucleotide reductase; Region: RNR_I; cd01679
235279004593	active site
235279004594	dimer interface [polypeptide binding]; other site
235279004595	catalytic residues [active]
235279004596	effector binding site; other site
235279004597	R2 peptide binding site; other site
235279004598	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
235279004599	peptide chain release factor 1; Validated; Region: prfA; PRK00591
235279004600	This domain is found in peptide chain release factors; Region: PCRF; smart00937
235279004601	RF-1 domain; Region: RF-1; pfam00472
235279004602	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
235279004603	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
235279004604	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
235279004605	active site
235279004606	substrate binding site [chemical binding]; other site
235279004607	metal binding site [ion binding]; metal-binding site
235279004608	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
235279004609	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
235279004610	Protein of unknown function (DUF466); Region: DUF466; pfam04328
235279004611	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
235279004612	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279004613	dimer interface [polypeptide binding]; other site
235279004614	conserved gate region; other site
235279004615	putative PBP binding loops; other site
235279004616	ABC-ATPase subunit interface; other site
235279004617	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
235279004618	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
235279004619	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
235279004620	dimer interface [polypeptide binding]; other site
235279004621	conserved gate region; other site
235279004622	putative PBP binding loops; other site
235279004623	ABC-ATPase subunit interface; other site
235279004624	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
235279004625	ABC transporter; Region: ABC_tran; pfam00005
235279004626	Q-loop/lid; other site
235279004627	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
235279004628	ABC transporter signature motif; other site
235279004629	Walker B; other site
235279004630	D-loop; other site
235279004631	H-loop/switch region; other site
235279004632	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
235279004633	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
235279004634	Walker A/P-loop; other site
235279004635	ATP binding site [chemical binding]; other site
235279004636	Q-loop/lid; other site
235279004637	ABC transporter signature motif; other site
235279004638	Walker B; other site
235279004639	D-loop; other site
235279004640	H-loop/switch region; other site
235279004641	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
235279004642	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
235279004643	minor groove reading motif; other site
235279004644	helix-hairpin-helix signature motif; other site
235279004645	active site
235279004646	fumarate hydratase; Provisional; Region: PRK06246
235279004647	Fumarase C-terminus; Region: Fumerase_C; cl00795
235279004648	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
235279004649	flagellin B; Provisional; Region: PRK13588
235279004650	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
235279004651	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
235279004652	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
235279004653	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
235279004654	DNA topoisomerase I; Validated; Region: PRK05582
235279004655	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
235279004656	active site
235279004657	interdomain interaction site; other site
235279004658	putative metal-binding site [ion binding]; other site
235279004659	nucleotide binding site [chemical binding]; other site
235279004660	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
235279004661	domain I; other site
235279004662	DNA binding groove [nucleotide binding]
235279004663	phosphate binding site [ion binding]; other site
235279004664	domain II; other site
235279004665	domain III; other site
235279004666	nucleotide binding site [chemical binding]; other site
235279004667	catalytic site [active]
235279004668	domain IV; other site
235279004669	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
235279004670	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
235279004671	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
235279004672	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
235279004673	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
235279004674	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
235279004675	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
235279004676	dimer interface [polypeptide binding]; other site
235279004677	anticodon binding site; other site
235279004678	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
235279004679	homodimer interface [polypeptide binding]; other site
235279004680	motif 1; other site
235279004681	active site
235279004682	motif 2; other site
235279004683	GAD domain; Region: GAD; pfam02938
235279004684	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
235279004685	active site
235279004686	motif 3; other site
235279004687	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
235279004688	Response regulator receiver domain; Region: Response_reg; pfam00072
235279004689	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
235279004690	active site
235279004691	phosphorylation site [posttranslational modification]
235279004692	intermolecular recognition site; other site
235279004693	dimerization interface [polypeptide binding]; other site
235279004694	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
235279004695	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
235279004696	nucleotide binding pocket [chemical binding]; other site
235279004697	K-X-D-G motif; other site
235279004698	catalytic site [active]
235279004699	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
235279004700	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
235279004701	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
235279004702	Dimer interface [polypeptide binding]; other site
235279004703	BRCT sequence motif; other site
235279004704	Domain of unknown function (DUF386); Region: DUF386; cl01047
235279004705	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
235279004706	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
235279004707	metal binding site [ion binding]; metal-binding site
235279004708	dimer interface [polypeptide binding]; other site
235279004709	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
235279004710	active site
235279004711	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
235279004712	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
235279004713	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
235279004714	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
235279004715	putative active site [active]
235279004716	histidyl-tRNA synthetase; Region: hisS; TIGR00442
235279004717	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
235279004718	dimer interface [polypeptide binding]; other site
235279004719	motif 1; other site
235279004720	active site
235279004721	motif 2; other site
235279004722	motif 3; other site
235279004723	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
235279004724	anticodon binding site; other site
235279004725	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
235279004726	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
235279004727	active site
235279004728	Zn binding site [ion binding]; other site
235279004729	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
235279004730	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
235279004731	putative metal binding site [ion binding]; other site
235279004732	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
235279004733	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
235279004734	dimer interface [polypeptide binding]; other site
235279004735	catalytic triad [active]
235279004736	peroxidatic and resolving cysteines [active]
235279004737	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
235279004738	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
235279004739	putative active site [active]
235279004740	PhoH-like protein; Region: PhoH; pfam02562
235279004741	Sporulation related domain; Region: SPOR; pfam05036
235279004742	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
235279004743	NlpC/P60 family; Region: NLPC_P60; pfam00877
235279004744	phosphoenolpyruvate synthase; Validated; Region: PRK06464
235279004745	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
235279004746	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
235279004747	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
235279004748	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
235279004749	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
235279004750	dimerization interface [polypeptide binding]; other site
235279004751	ATP binding site [chemical binding]; other site
235279004752	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
235279004753	dimerization interface [polypeptide binding]; other site
235279004754	ATP binding site [chemical binding]; other site
235279004755	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279004756	Sel1-like repeats; Region: SEL1; smart00671
235279004757	Sel1-like repeats; Region: SEL1; smart00671
235279004758	Sel1-like repeats; Region: SEL1; smart00671
235279004759	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
235279004760	Sel1-like repeats; Region: SEL1; smart00671
235279004761	Sel1-like repeats; Region: SEL1; smart00671
235279004762	Sel1-like repeats; Region: SEL1; smart00671
235279004763	Sel1-like repeats; Region: SEL1; smart00671
235279004764	Sel1-like repeats; Region: SEL1; smart00671
235279004765	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
235279004766	thiamine phosphate binding site [chemical binding]; other site
235279004767	active site
235279004768	pyrophosphate binding site [ion binding]; other site
235279004769	arginyl-tRNA-protein transferase; Provisional; Region: PRK01305
235279004770	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
235279004771	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
235279004772	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
235279004773	murein transglycosylase C; Provisional; Region: mltC; PRK11671
235279004774	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
235279004775	N-acetyl-D-glucosamine binding site [chemical binding]; other site
235279004776	catalytic residue [active]
235279004777	Radical SAM superfamily; Region: Radical_SAM; pfam04055
235279004778	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
235279004779	FeS/SAM binding site; other site
235279004780	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
235279004781	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
235279004782	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
235279004783	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
235279004784	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
235279004785	dimerization interface [polypeptide binding]; other site
235279004786	active site
235279004787	thiamine monophosphate kinase; Provisional; Region: PRK05731
235279004788	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
235279004789	dimerization interface [polypeptide binding]; other site
235279004790	ATP binding site [chemical binding]; other site
235279004791	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
235279004792	active site
235279004793	dimerization interface [polypeptide binding]; other site
235279004794	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
235279004795	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
235279004796	quinolinate synthetase; Provisional; Region: PRK09375
235279004797	serine endoprotease; Provisional; Region: PRK10139
235279004798	UGMP family protein; Validated; Region: PRK09604
235279004799	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
235279004800	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
235279004801	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
235279004802	DJ-1 family protein; Region: not_thiJ; TIGR01383
235279004803	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
235279004804	conserved cys residue [active]
235279004805	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
235279004806	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
235279004807	active site
235279004808	DNA binding site [nucleotide binding]
235279004809	Int/Topo IB signature motif; other site
235279004810	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
235279004811	active site
235279004812	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
235279004813	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
235279004814	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
235279004815	dimer interface [polypeptide binding]; other site
235279004816	substrate binding site [chemical binding]; other site
235279004817	metal binding sites [ion binding]; metal-binding site
235279004818	acetyl-CoA carboxylase subunit A; Validated; Region: PRK08463
235279004819	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
235279004820	ATP-grasp domain; Region: ATP-grasp_4; cl17255
235279004821	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
235279004822	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
235279004823	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
235279004824	putative substrate binding site [chemical binding]; other site
235279004825	putative ATP binding site [chemical binding]; other site
235279004826	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
235279004827	ThiS interaction site; other site
235279004828	putative active site [active]
235279004829	tetramer interface [polypeptide binding]; other site
235279004830	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
235279004831	Leucine rich repeat; Region: LRR_8; pfam13855
235279004832	Leucine-rich repeats, typical (most populated) subfamily; Region: LRR_TYP; cl15310
235279004833	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
235279004834	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
235279004835	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
235279004836	FtsX-like permease family; Region: FtsX; pfam02687
235279004837	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
235279004838	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
235279004839	Walker A/P-loop; other site
235279004840	ATP binding site [chemical binding]; other site
235279004841	Q-loop/lid; other site
235279004842	ABC transporter signature motif; other site
235279004843	Walker B; other site
235279004844	D-loop; other site
235279004845	H-loop/switch region; other site
235279004846	macrolide transporter subunit MacA; Provisional; Region: PRK11578
235279004847	HlyD family secretion protein; Region: HlyD_3; pfam13437
235279004848	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
235279004849	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
235279004850	Protein of unknown function (DUF3897); Region: DUF3897; pfam13036
235279004851	LPP20 lipoprotein; Region: LPP20; pfam02169
235279004852	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase; Provisional; Region: PRK14022
235279004853	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
235279004854	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
235279004855	NifU-like domain; Region: NifU; cl00484
235279004856	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
235279004857	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
235279004858	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
235279004859	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
235279004860	DctM-like transporters; Region: DctM; pfam06808
235279004861	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
235279004862	Phosphate transporter family; Region: PHO4; pfam01384
235279004863	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
235279004864	Domain of unknown function DUF21; Region: DUF21; pfam01595
235279004865	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
235279004866	Transporter associated domain; Region: CorC_HlyC; smart01091
235279004867	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
235279004868	substrate binding site [chemical binding]; other site
235279004869	active site
235279004870	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
235279004871	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
235279004872	carbon starvation protein A; Provisional; Region: PRK15015
235279004873	Carbon starvation protein CstA; Region: CstA; pfam02554
235279004874	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722