-- dump date 20140619_112408 -- class Genbank::CDS -- table cds_note -- id note NP_859532.1 similar to Helicobacter pylori toxin-like outer membrane protein NP_859534.1 similar to Streptomyces coelicolor lipoprotein NP_859535.1 similar to GGDEF family protein NP_859536.1 similar to Campylobacter jejuni iron-binding protein; GGDEF family protein NP_859538.1 similar to Helicobacter pylori Hop-family proteins NP_859539.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_859540.1 involved in the peptidyltransferase reaction during translation NP_859542.1 similar to Campylobacter jejuni periplasmic protein; related to metalloendopeptidases NP_859543.1 similar to Campylobacter jejuni transcriptional regulator Cj0466 NP_859544.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_859545.1 similar to Helicobacter pylori HP0232 secreted protein involved in flagellar motility NP_859546.1 similar to Helicobacter pylori HP0233 NP_859547.1 predicted secreted protein NP_859549.1 similar to Helicobacter pylori HP0820 NP_859550.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_859554.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_859555.1 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_859556.1 similar to Helicobacter pylori HP1089 NP_859557.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_859558.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_859559.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_859561.1 similar to methyltransferases involved in tellurite resistance NP_859562.1 possible cation efflux pump NP_859565.1 predicted secreted protein NP_859566.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_859567.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_859568.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_859569.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_859570.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis NP_859572.1 predicted membrane-associated NP_859575.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate NP_859577.1 small subunit NP_859578.1 large subunit NP_859580.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis NP_859583.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_859584.1 similar to Vibrio cholerae VC0082; predicted secreted protein NP_859585.1 similar to Yersinia pestis YPO2377; predicted membrane-associated NP_859592.1 similar to Campylobacter jejuni periplasmic protein NP_859595.1 similar to Bacteroides fragilis glycosyl transferase NP_859597.1 similar to sugar transferase; may become fused with HH0067 due to slipped strand mispairing NP_859598.1 similar to sugar transferase; may become fused with HH0066 due to slipped strand misparing NP_859599.1 similar to Streptococcus gordonii probable glycosyl transferase NP_859600.1 may become fused with HH0070 due to slipped strand mispairing NP_859601.1 may become fused with HH0069 due to slipped strand mispairing NP_859602.1 predicted aminotransferase NP_859603.1 predicted fucosyltransferase NP_859604.1 predicted glycosyltransferase NP_859605.1 possibly related to methylase involved in ubiquinone/menaquinone biosynthesis; cyclopropane fatty acid synthase and related methyltransferases NP_859607.1 similar to Salmonella typhi methyltransferase NP_859608.1 predicted secreted protein NP_859612.1 similar to glycosyltransferases NP_859615.1 similar to Campylobacter jejuni CJ1302 NP_859616.1 similar to Campylobacter jejuni CJ1301; may become fused with HH0086 due to slipped strand mispairing NP_859617.1 similar to Campylobacter jejuni CJ1301; may become fused with HH0085 due to slipped strand mispairing NP_859621.1 similar to Haemophilus influenzae O-succinylbenzoate-CoA ligase NP_859623.1 similar to Escherichia coli 3-oxoacyl-[acyl-carrier-protein] reductase NP_859626.1 similar to Campylobacter jejuni acetyl transferase NP_859631.1 similar to Campylobacter jejuni glucose-1-phosphate thymidyltransferase NP_859632.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_859634.1 predicted membrane-associated NP_859635.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis NP_859636.1 possible parvulin-like peptidyl-prolyl isomerase NP_859637.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_859639.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_859640.1 ATP-binding subunit NP_859641.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_859643.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_859646.1 protein component NP_859647.1 in Escherichia coli transcription of this gene is enhanced by polyamines NP_859648.1 predicted secreted protein NP_859649.1 predicted membrane-associated NP_859650.1 ExbD-like NP_859651.1 ExbB-like NP_859652.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_859653.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis NP_859654.1 affects carbohydrate metabolism, has regulatory role in many processes NP_859655.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_859656.1 predicted secreted protein NP_859657.1 predicted membrane-associated NP_859658.1 HIT family NP_859659.1 similar to Campylobacter jejuni UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate ligase NP_859660.1 possible acylphosphatase NP_859661.1 similar to Helicobacter pylori JHP0676 NP_859662.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_859663.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_859664.1 predicted secreted protein NP_859666.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate NP_859667.1 similar to Helicobacter pylori HP0398; predicted secreted protein NP_859668.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_859669.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_859670.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_859672.1 similar to Campylobacter jejuni CJ1463 NP_859673.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum NP_859674.1 similar to Helicobacter pylori JHP1024; predicted secreted protein NP_859676.1 predicted secreted protein NP_859677.1 similar to Helicobacter pylori HP1515 NP_859678.1 predicted secreted protein NP_859679.1 predicted secreted protein NP_859680.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ NP_859681.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP NP_859682.1 similar to Helicobacter pylori JHP0797; predicted secreted protein NP_859683.1 similar to Helicobacter pylori JHP0798; predicted membrane-associated NP_859684.1 catalyzes the formation of dUMP from dUTP NP_859685.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_859687.1 similar to Campylobacter jejuni dehydrogenase CJ1505 NP_859689.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC NP_859690.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway NP_859691.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA NP_859692.1 small subunit NP_859693.1 similar to Campylobacter jejuni periplasmic protein CJ0784 NP_859695.1 similar to Campylobacter jejuni CJ0465c NP_859696.1 similar to Helicobacter pylori HP1502; predicted membrane-associated NP_859697.1 similar to Campylobacter jejuni transcriptional regulator Cj0466 NP_859698.1 possible cation efflux pump NP_859699.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS NP_859701.1 predicted secreted protein NP_859702.1 predicted membrane-associated NP_859704.1 similar to Campylobacter jejuni fucose synthetase NP_859705.1 possible cation efflux pump NP_859706.1 possible cation efflux pump NP_859707.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 NP_859708.1 similar to Campylobacter jejuni membrane protein CJ0341c NP_859709.1 Involved in the metabolism of aromatic amino acids NP_859710.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_859711.1 similar to Helicobacter pylori JHP0087 NP_859712.1 may become fused with HH0182 due to slipped strand mispairing NP_859713.1 may become fused with HH0181 due to slipped strand mispairing NP_859714.1 the hook connects flagellar basal body to the flagellar filament NP_859715.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod NP_859718.1 similar to Neisseria meningitidis periplasmic protein NP_859719.1 predicted secreted protein NP_859720.1 predicted secreted protein NP_859721.1 predicted secreted protein NP_859722.1 predicted membrane-associated NP_859724.2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_859726.1 biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_859728.1 predicted aminotransferase NP_859729.1 similar to Campylobacter jejuni small Ni/fe-hydrogenase CJ1399c NP_859732.1 predicted membrane-associated NP_859733.1 similar to tellurite resistance permeases NP_859737.1 similar to Klebsiella pneumonia RFBC protein NP_859738.1 similar to Klebsiella pneumonia RFBC protein NP_859739.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate NP_859746.1 cytochrome c-type protein NP_859747.1 similar to Campylobacter jejuni periplasmic cytochrome c CJ1357c NP_859748.1 similar to cytochrome c-type proteins NP_859752.1 predicted secreted protein NP_859753.1 similar to Helicobacter pylori resistance-nodulation-division efflux system protein HefC NP_859754.1 similar to Helicobacter pylori resistance-nodulation-division efflux system protein HefB NP_859755.1 similar to Helicobacter pylori resistance-nodulation-division efflux system protein HefA NP_859756.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth NP_859757.1 gamma subunit NP_859759.1 similar to Campylobacter jejuni formate dehydrogenase; iron-sulfur subunit NP_859760.1 similar to Campylobacter jejuni formate dehydrogenase; large subunit NP_859761.1 similar to Campylobacter jejuni possible periplasmic protein CJ1513c NP_859763.1 similar to Campylobacter jejuni ferredoxin CJ1377c NP_859764.1 predicted membrane-associated NP_859765.1 predicted membrane-associated NP_859767.1 predicted membrane-associated NP_859772.1 predicted membrane-associated NP_859774.1 similar to Vibrio cholerae hcp protein VCA0017 and VC1415 NP_859775.1 similar to Vibrio cholerae VCA0111 NP_859776.1 similar to Vibrio cholerae VCA0110 NP_859777.1 similar to Vibrio cholerae VCA0109 NP_859778.1 similar to Vibrio cholerae VCA0108 NP_859779.1 similar to Vibrio cholerae VCA0107 NP_859780.1 similar to Vibrio cholerae VCA0113 NP_859781.1 similar to Vibrio cholerae VCA0114 NP_859782.1 similar to Vibrio cholerae VCA0115 NP_859783.1 similar to Vibrio cholerae IcmF; VirB10-like protein NP_859786.1 predicted membrane-associated NP_859789.1 predicted membrane-associated NP_859791.1 virB4-like protein NP_859792.1 predicted membrane-associated NP_859794.1 predicted membrane-associated NP_859798.1 predicted membrane-associated NP_859799.1 similar to Campylobacter jejuni periplasmic protein NP_859806.1 virD4-like protein NP_859815.1 predicted secreted protein NP_859818.1 predicted membrane-associated NP_859821.1 predicted secreted protein NP_859824.1 predicted membrane-associated NP_859825.1 predicted membrane-associated NP_859826.1 predicted membrane-associated NP_859827.1 predicted membrane-associated NP_859829.1 predicted membrane-associated NP_859831.1 predicted membrane-associated NP_859832.1 predicted secreted protein NP_859837.1 acyl transferase NP_859838.1 similar to Campylobacter jejuni periplasmic protein NP_859839.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_859840.1 heat shock protein involved in degradation of misfolded proteins NP_859841.1 heat shock protein involved in degradation of misfolded proteins NP_859842.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_859844.1 predicted secreted protein NP_859845.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis NP_859847.1 participates with LolB in the incorporation of lipoprotein into the outer membrane NP_859848.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_859849.1 similar to Campylobacter jejuni integral membrane protein CJ0941c NP_859850.1 possible RNA-binding protein with RRM domain NP_859852.1 possible helicase subunit NP_859854.1 similar to Helicobacter pylori lipopolysaccharide biosynthesis protein HP0805 NP_859858.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_859859.1 similar to Campylobacter jejuni CJ1113 NP_859860.1 may become fused with HH0330 due to slipped strand mispairing NP_859861.1 may become fused with HH0329 due to slipped strand mispairing NP_859862.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_859863.1 similar to Campylobacter jejuni CJ1642 NP_859864.1 similar to Helicobacter pylori HP0036; predicted secreted protein NP_859866.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate NP_859867.1 similar to Helicobacter pylori JHP0692; MoeB/ThiF family NP_859868.1 similar to Helicobacter pylori JHP0693 NP_859869.1 similar to Campylobacter jejuni hydrolase CJ0947c NP_859870.1 similar to Pseudomonas aeruginosa PA4578; predicted secreted protein NP_859871.1 similar to Pseudomonas aeruginosa PA4579 NP_859872.1 similar to Campylobacter jejuni CJ1254 NP_859873.1 predicted membrane-associated NP_859874.1 predicted secreted protein NP_859875.1 predicted membrane-associated NP_859877.1 similar to amino acid ABC transporter permeases NP_859878.1 similar to amino acid ABC transporter ATP binding components NP_859880.1 predicted secreted protein NP_859881.1 similar to Helicobacter pylori HP1414 NP_859882.1 similar to Helicobacter pylori HP1337 NP_859883.1 Inhibits transcription at high concentrations of nickel NP_859884.1 ExbB-like NP_859885.1 ExbD-like NP_859888.1 predicted secreted protein NP_859889.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_859890.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_859891.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_859892.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_859893.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_859894.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_859895.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_859896.1 binds directly to 23S ribosomal RNA NP_859897.1 Modulates Rho-dependent transcription termination NP_859898.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_859899.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_859900.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_859901.1 predicted membrane-associated NP_859903.1 similar to Helicobacter pylori HP0624; predicted aminotransferase NP_859904.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_859905.1 predicted membrane-associated NP_859906.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange NP_859907.1 predicted membrane-associated NP_859909.1 similar to Campylobacter jejuni CJ0904c NP_859910.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters NP_859912.1 predicted secreted protein NP_859916.1 predicted membrane-associated NP_859918.1 predicted membrane-associated NP_859920.1 predicted membrane-associated NP_859922.1 predicted membrane-associated NP_859924.1 predicted membrane-associated NP_859928.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate NP_859929.1 involved in propionate metabolism NP_859930.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C NP_859934.1 predicted membrane-associated NP_859935.1 predicted membrane-associated NP_859936.1 similar to Campylobacter jejuni acid periplasmic protein CJ0424 NP_859937.1 predicted membrane-associated NP_859938.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits NP_859939.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits NP_859941.2 involved in the assembly of the urease metallocenter; possible nickel donor NP_859949.1 similar to Pseudomonas aeruginosa outer membrane hemin receptor NP_859950.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_859951.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_859952.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon NP_859955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. NP_859956.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_859957.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The delta subunit is part of the catalytic core of the ATP synthase complex NP_859958.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_859959.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_859960.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_859961.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_859962.1 ExbB-like NP_859964.1 similar to Helicobacter pylori HP1127; predicted secreted protein NP_859965.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA NP_859966.1 MotB-family NP_859967.1 similar to Helicobacter pylori HP1124; predicted secreted protein NP_859968.1 rotamase NP_859969.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus NP_859970.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_859972.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_859973.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_859974.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_859976.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_859977.1 similar to Helicobacter pylori HP1044; predicted membrane-associated NP_859979.1 predicted membrane-associated NP_859981.1 similar to Helicobacter pylori JHP0233; predicted membrane-associated NP_859982.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_859983.1 similar to Campylobacter jejuni CJ1249 NP_859985.1 similar to Campylobacter jejuni HtrA NP_859988.1 similar to Helicobacter pylori HP1436; predicted membrane-associated NP_859990.1 similar to Helicobacter pylori HP1542 NP_859991.1 similar to Helicobacter pylori HP1543 NP_859992.1 similar to Vibrio cholerae TagE (VC0843) NP_859995.1 similar to Helicobacter pylori HP1546 NP_859996.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_859997.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer NP_859998.1 membrane protein involved in the flagellar export apparatus NP_859999.1 similar to Helicobacter pylori HP1042 NP_860002.1 similar to Helicobacter pylori ion-channel HP1183 NP_860003.1 similar to Campylobacter jejuni CJ0601c NP_860004.1 similar to Helicobacter pylori HP1252 NP_860005.1 similar to Campylobacter jejuni CJ0377 NP_860006.1 predicted secreted protein NP_860007.1 predicted secreted protein NP_860009.1 similar to Helicobacter pylori HP1079 NP_860012.1 similar to methyl-accepting chemotaxis proteins; similar to Campylobacter jejuni CJ1506c NP_860013.1 similar to Helicobacter pylori HP1321 NP_860014.2 involved in de novo purine biosynthesis NP_860015.1 similar to Campylobacter jejuni CJ1132c NP_860018.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_860019.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_860020.1 similar to Escherichia coli YhcC NP_860021.1 similar to Helicobacter pylori periplasmic protein NP_860022.1 catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate NP_860023.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_860026.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate NP_860027.1 predicted secreted protein NP_860028.1 similar to Campylobacter jejuni CJ0546 NP_860029.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_860030.1 forms a direct contact with the tRNA during translation NP_860031.1 similar to Campylobacter jejuni CJ0809c NP_860032.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine NP_860033.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine NP_860034.1 may become fused with HH0504 due to slipped strand mispairing NP_860035.1 may become fused with HH0503 due to slipped strand mispairing NP_860036.1 predicted membrane-associated NP_860037.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_860038.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_860039.1 similar to Campylobacter jejuni CJ1174 NP_860041.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_860044.1 similar to methyl-accepting chemotaxis proteins NP_860045.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_860047.1 similar to Escherichia coli MviN; predicted membrane-associated NP_860048.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_860049.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_860050.1 similar to Helicobacter pylori HP1086 NP_860052.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_860053.1 similar to Helicobacter pylori HP1083; predicted secreted protein NP_860055.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_860056.1 similar to Helicobacter pylori Hop-family proteins NP_860058.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_860059.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway NP_860060.1 similar to Campylobacter jejuni Cj0703 NP_860061.1 similar to Campylobacter jejuni CJ0703 NP_860062.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_860063.1 similar to Campylobacter jejuni periplasmic protein NP_860065.1 predicted ribonuclease; similar to Helicobacter pylori HP1248 NP_860066.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA NP_860067.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_860068.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_860069.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_860070.1 predicted membrane-associated NP_860072.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_860076.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria NP_860077.1 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin NP_860078.1 Couples the complete acetyl-CoA oxidation to aromatic ring reduction by the use of the low-potential electron shuttle ferredoxin NP_860080.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates NP_860085.1 predicted secreted protein NP_860086.1 predicted membrane-associated NP_860089.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_860090.1 predicted secreted protein NP_860092.1 similar to Campylobacter jejuni CJ0829c NP_860095.1 catalyzes the removal of sulfur from cysteine to form alanine NP_860096.1 involved in type III protein export during flagellum assembly NP_860097.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_860098.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_860100.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_860102.1 similar to Campylobacter jejuni CJ0510c NP_860103.1 similar to Campylobacter jejuni CJ1050c; Sir2 family protein NP_860104.1 predicted membrane-associated NP_860106.1 predicted secreted protein NP_860107.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_860108.1 similar to Helicobacter pylori JHP0592; predicted secreted protein NP_860111.1 similar to Campylobacter jejuni secreted transglycosylase CJ0843c NP_860112.1 similar to Campylobacter jejuni integral membrane protein CJ0844c NP_860113.1 charges one glutamine molecule and pairs it with tRNA(Gln) NP_860114.1 similar to Helicobacter pylori JHP0349 NP_860116.1 predicted transporter protein NP_860117.1 similar to Helicobacter pylori CadA (JHP0727) NP_860118.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP NP_860119.1 similar to Campylobacter jejuni CJ1208; possible 5-formyltetrahydrofolate cyclo-ligase NP_860120.1 similar to Campylobacter jejuni signal recognition particle protein NP_860122.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_860123.1 similar to Campylobacter jejuni possible sugar transferase NP_860124.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 NP_860126.1 similar to Helicobacter pylori HP1214 NP_860127.1 Imp/OstA-like NP_860128.1 similar to Campylobacter jejuni CJ1251; predicted membrane-associated NP_860129.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_860132.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_860133.1 similar to Helicobacter pylori JHP1018; predicted membrane-associated NP_860135.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins NP_860136.1 similar to Aquifex aeolicus AQ_103 NP_860137.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_860139.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_860140.1 binds to and inhibits the function of flagella specific ATPase FliI NP_860141.1 One of three proteins involved in switching the direction of the flagellar rotation NP_860142.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod NP_860143.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_860145.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_860146.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_860148.1 hydrolyzes diadenosine polyphosphate NP_860149.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. NP_860151.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_860154.1 similar to Helicobacter pylori resistance-nodulation-division efflux system protein HefF NP_860155.1 similar to Helicobacter pylori resistance-nodulation-division efflux system protein HefE NP_860156.1 similar to Helicobacter pylori resistance-nodulation-division efflux system protein HefD NP_860157.1 similar to Campylobacter jejuni CJ0504c NP_860158.1 similar to degT family amidotransferases NP_860159.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_860160.1 similar to Helicobacter pylori JHP0144; predicted secreted protein NP_860161.1 similar to Campylobacter jejuni CJ1671c; predicted membrane-associated NP_860162.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_860164.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_860165.1 similar to Campylobacter jejuni CJ1674 NP_860166.1 similar to Helicobacter pylori HP0567; predicted membrane-associated NP_860168.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis NP_860169.1 similar to Campylobacter jejuni CJ0705 NP_860170.1 similar to Helicobacter pylori HP0958 NP_860171.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A NP_860174.1 predicted secreted protein NP_860179.1 similar to Dichelobacter nodosus lipopolysaccharide biosynthesis protein LpsA NP_860181.1 similar to Helicobacter pylori JHP0127; predicted secreted protein NP_860182.1 similar to Helicobacter pylori HP0138 NP_860183.1 similar to Helicobacter pylori JHP0125 NP_860184.1 possible molybdenum transport protein ModE NP_860189.1 similar to Campylobacter jejuni CJ0701; predicted protease NP_860190.1 similar to Helicobacter pylori JHP0156 NP_860191.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_860192.1 similar to Helicobacter pylori HP0839; predicted outer membrane protein NP_860194.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_860195.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_860196.1 Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction NP_860198.1 similar to Helicobacter pylori HP0112 NP_860199.1 predicted peptidase NP_860200.2 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_860201.1 similar to Helicobacter pylori JHP0987 NP_860202.1 similar to Helicobacter pylori HP0393 (CheV3) NP_860205.1 similar to Campylobacter jejuni CJ0282 NP_860206.1 probable mannose-1-phosphate guanylyltransferase ManC NP_860207.1 similar to Helicobacter pylori HP0421; predicted glycosyl transferase NP_860209.1 similar to Campylobacter jejuni small hydrophobic protein NP_860210.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_860211.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_860212.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_860213.1 similar to Helicobacter pylori HP0791; probable cation transport ATPase NP_860214.1 similar to Helicobacter pylori copper ion binding protein HP1073 NP_860216.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit NP_860217.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB NP_860218.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB NP_860219.1 similar to Helicobacter pylori HP0190; predicted secreted protein NP_860221.1 similar to Campylobacter jejuni CJ1047c NP_860222.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_860223.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus NP_860224.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs NP_860225.1 similar to Campylobacter jejuni CJ1241; possible permease NP_860227.1 similar to Helicobacter pylori JHP0604 NP_860228.1 similar to Helicobacter pylori HP0660; predicted secreted protein NP_860229.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_860230.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_860231.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_860232.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_860233.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_860235.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus NP_860236.1 membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation NP_860237.1 similar to Campylobacter jejuni CJ1178c NP_860238.1 Essential for recycling GMP and indirectly, cGMP NP_860239.1 similar to Campylobacter jejuni CJ1176c NP_860240.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_860241.1 similar to Helicobacter pylori HP1331; predicted membrane-associated NP_860242.1 similar to Helicobacter pylori HP1330; predicted membrane-associated NP_860243.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_860244.1 similar to Helicobacter pylori HP1564; predicted outer membrane protein NP_860245.1 similar to Helicobacter pylori outer membrane protein HP1564 NP_860246.1 similar to Helicobacter pylori HP1577; predicted ABC transporter permease component NP_860247.1 part of the metNIQ transport system for methionine NP_860248.1 similar to Helicobacter pylori HP1459; possible pseudouridine synthase NP_860249.1 similar to Helicobacter pylori JHP0571; predicted secreted protein NP_860251.1 predicted secreted protein NP_860252.1 similar to Campylobacter jejuni/coli siderophore receptor protein CfrA NP_860253.1 catalyzes the formation of fumarate from aspartate NP_860254.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB NP_860255.1 predicted membrane-associated NP_860256.1 similar to methyl-accepting chemotaxis protein; similar to Campylobacter jejuni CJ1506c NP_860257.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein NP_860258.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_860263.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_860264.1 similar to Helicobacter pylori HP0597; predicted penicillin binding protein NP_860265.1 predicted membrane-associated NP_860266.1 similar to Helicobacter pylori HP0347; predicted pseudouridylate synthase NP_860267.1 predicted membrane-associated NP_860270.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_860271.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis NP_860275.1 similar to Helicobacter pylori HP0031 NP_860276.1 predicted secreted protein NP_860277.1 predicted secreted protein NP_860283.1 similar to Campylobacter coli; predicted phage transposition protein MuB NP_860285.1 similar to Campylobacter coli; predicted host-nuclease inhibitor protein Gam NP_860293.1 predicted secreted protein NP_860294.1 predicted secreted protein NP_860295.1 predicted membrane-associated NP_860296.1 predicted membrane-associated NP_860297.1 predicted secreted protein NP_860302.1 predicted membrane-associated NP_860304.1 similar to Campylobacter jejuni CJ1135; predicted glycosyl transferase NP_860305.1 similar to Helicobacter pylori JHP1312; predicted membrane-associated NP_860306.1 predicted membrane-associated NP_860307.1 ATP binding component NP_860308.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_860309.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_860311.1 similar to Helicobacter pylori JHP0911; predicted secreted protein NP_860312.1 predicted membrane-associated NP_860315.1 similar to Helicobacter pylori JHP0683; predicted secreted protein NP_860316.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_860317.1 ATP-binding component; possibly involved in cell division NP_860319.1 similar to Helicobacter pylori HP0750 NP_860320.1 possibly involved in flagella export NP_860321.1 involved in flagellin assembly NP_860322.1 flagellin specific chaperone NP_860323.1 similar to Helicobacter pylori HP0754 NP_860324.1 similar to Campylobacter jejuni CJ0913c NP_860325.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_860326.1 predicted secreted protein NP_860327.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_860328.1 possible SNF2 family helicase NP_860329.1 similar to Helicobacter pylori JHP1409; predicted type II DNA modification enzyme (methyltransferase) NP_860331.1 similar to Helicobacter pylori JHP0346 NP_860335.1 predicted secreted protein NP_860336.1 similar to Campylobacter jejuni CJ0256; predicted membrane-associated NP_860338.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_860339.1 plays a role in hydrogenase nickel cofactor insertion NP_860341.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM NP_860342.1 similar to Helicobacter pylori HP0497; sodium-dependent transporter NP_860343.1 similar to Helicobacter pylori Hop-family proteins NP_860346.1 predicted membrane-associated NP_860347.1 similar to Helicobacter pylori JHP1437; predicted secreted protein NP_860348.1 similar to Helicobacter pylori HP0727; predicted transcriptional regulator NP_860350.1 similar to Helicobacter pylori HP0019 (CheV1) NP_860352.1 similar to Helicobacter pylori JHP0354; predicted membrane-associated NP_860353.1 cell division protein FtsH NP_860355.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype NP_860357.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide NP_860358.1 predicted membrane-associated NP_860360.1 similar to Helicobacter pylori HP0773 NP_860361.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_860362.1 similar to guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase NP_860363.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_860364.1 Catalyzes the phosphorylation of UMP to UDP NP_860365.1 predicted secreted protein NP_860366.1 predicted secreted protein NP_860367.1 similar to Campylobacter jejuni CJ1249 NP_860368.1 similar to Helicobacter pylori HP1504 NP_860370.1 similar to Helicobacter pylori JHP0379 NP_860371.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_860372.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) NP_860373.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_860374.2 binds to flagellin and appears to stabilize flagellin during flagella assembly NP_860375.1 similar to Helicobacter pylori HP1378; predicted ComL-like lipoprotein NP_860379.1 predicted secreted protein NP_860381.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_860382.1 possible 5,10-methylenetetrahydrofolate reductase NP_860383.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_860385.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_860386.1 predicted membrane-associated NP_860387.1 similar to phage lambda cII repressor protease NP_860390.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_860391.1 similar to Helicobacter pylori HP1580; predicted membrane-associated NP_860392.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) NP_860393.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) NP_860394.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_860395.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine resistant; also known as acetolactate synthase 3 large subunit NP_860396.1 similar to Campylobacter jejuni predicted transport transmembrane protein CJ1040c NP_860397.1 similar to Campylobacter jejuni CJ202c; predicted secreted protein NP_860398.1 predicted membrane-associated NP_860399.1 similar to Campylobacter jejuni integral membrane protein CJ0201c NP_860400.1 subunit D NP_860401.1 similar to Campylobacter jejuni CJ1214c; predicted secreted protein NP_860402.1 similar to Helicobacter pylori HP0507 NP_860403.1 similar to Helicobacter pylori HP0506; predicted secreted protein NP_860404.1 predicted membrane-associated NP_860406.1 similar to Helicobacter pylori JHP1048 NP_860407.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook NP_860408.1 similar to Helicobacter pylori HP0174; predicted membrane-associated NP_860410.1 cell division protein FtsH NP_860411.1 similar to Helicobacter pylori HP0285 NP_860412.1 similar to Helicobacter pylori HP0284; predicted membrane-associated NP_860413.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_860414.1 similar to Helicobacter pylori HP0282 NP_860415.1 similar to Helicobacter pylori HP0778 NP_860416.1 similar to Helicobacter pylori HP0495 NP_860417.1 similar to Helicobacter pylori HP0496 NP_860418.1 similar to Helicobacter pylori sodium- and chloride-dependent transporter NP_860419.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_860420.1 similar to Helicobacter pylori JHP1157 NP_860422.1 similar to Helicobacter pylori JHP0546; predicted methyl-accepting chemotaxis protein (MCP) NP_860426.1 similar to Helicobacter pylori conserved hypothetical integral membrane protein NP_860427.1 catalyzes the formation of 2-oxobutanoate from L-threonine NP_860428.1 similar to Helicobacter pylori HP1234; predicted membrane-associated NP_860430.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod NP_860432.1 similar to Campylobacter jejuni CJ0761 NP_860434.1 predicted secreted protein NP_860438.1 flagellar modification protein NP_860440.1 possible aminotransferase NP_860441.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_860443.1 similar to Helicobacter pylori HP0920; predicted membrane-associated NP_860444.1 possible ferredoxin-like protein; predicted membrane-associated NP_860445.1 ATP-binding protein NP_860447.1 predicted secreted protein NP_860450.1 similar to Helicobacter pylori HP0952; CinA/YgaD-like NP_860451.1 similar to Campylobacter jejuni CJ0604 NP_860454.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX NP_860455.1 similar to Helicobacter pylori JHP1403; predicted dihydroneopterin aldolase NP_860457.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_860458.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_860460.1 possible uracil-DNA glycosylase NP_860461.1 similar to Helicobacter pylori HP0275; predicted secreted protein NP_860463.1 binds to flagellin and appears to stabilize flagellin during flagella assembly NP_860464.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_860465.1 similar to Campylobacter jejuni CJ0760 NP_860466.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_860467.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_860469.1 similar to Campylobacter jejuni CJ0711 NP_860470.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_860472.1 predicted membrane-associated NP_860473.1 FurR family NP_860474.1 similar to Helicobacter pylori JHP0417 NP_860475.1 possible peptidase NP_860476.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_860478.1 similar to Helicobacter pylori JHP0703; predicted membrane-associated NP_860479.1 similar to Helicobacter pylori HP0764 NP_860482.1 similar to Campylobacter jejuni CJ0265c; predicted cytochrome c-type protein NP_860483.1 similar to Helicobacter pylori HP0257; predicted secreted protein NP_860484.1 similar to Caulobacter crescentus FliJ; similar to Helicobacter pylori HP0256 NP_860485.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_860486.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine NP_860487.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_860488.1 similar to Helicobacter pylori replication protein A NP_860491.1 predicted membrane-associated NP_860492.1 predicted secreted protein NP_860493.1 predicted membrane-associated NP_860494.1 similar to Campylobacter jejuni integral membrane protein; predicted membrane-associated NP_860495.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_860496.1 predicted secreted protein NP_860497.1 similar to Campylobacter jejuni periplasmic protein NP_860500.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine NP_860501.1 similar to Helicobacter pylori HP0812 NP_860502.1 similar to Campylobacter jejuni methyl-accepting chemotaxis signal transduction protein NP_860504.1 similar to Campylobacter jejuni CJ20248 NP_860505.1 similar to Helicobacter pylori JHP0611; predicted glycerol-3-phosphate dehydrogenase GlpC NP_860506.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_860507.1 similar to Helicobacter pylori HP0664 NP_860509.1 similar to Helicobacter pylori HP0838; predicted secreted protein NP_860510.1 similar to Campylobacter jejuni lipoprotein NP_860511.1 predicted glycosyl transferase NP_860512.1 glucosyl transferase NP_860513.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes NP_860518.1 predicted membrane-associated NP_860519.1 similar to Campylobacter jejuni periplasmic protein NP_860520.1 similar to Campylobacter jejuni CJ504c NP_860521.1 similar to Helicobacter pylori JHP0602; predicted protease NP_860522.1 similar to Helicobacter pylori JHP0601 NP_860524.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_860525.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_860526.1 similar to Helicobacter pylori HP0375; predicted membrane-associated NP_860527.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_860528.1 similar to Helicobacter pylori HP0377; predicted membrane-associated NP_860530.1 predicted secreted protein NP_860531.1 similar to Helicobacter pylori HP1162; predicted membrane-associated NP_860532.1 ATP-binding component NP_860533.1 similar to Helicobacter pylori secreted protein NP_860534.1 similar to Helicobacter pylori JHP1206; predicted secreted protein NP_860536.1 similar to two-component response regulator proteins NP_860537.1 cytochrome b subunit NP_860538.1 2Fe-2S subunit NP_860540.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate NP_860542.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_860543.1 similar to Helicobacter pylori HP1049 NP_860544.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_860545.1 similar to Helicobacter pylori JHP0374 NP_860546.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis NP_860547.1 blocks the formation of polar Z-ring septums NP_860548.1 similar to Campylobacter jejuni CJ0131; predicted secreted protein NP_860549.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export NP_860550.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis NP_860551.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_860552.1 similar to Campylobacter jejuni CJ1368 NP_860553.1 P-type; CopA-like NP_860554.1 similar to Campylobacter jejuni CJ0069 NP_860556.1 similar to Escherichia coli Z1202; predicted helicase NP_860557.1 similar to Thermotoga maritima oxidoreductasealdo/keto reductase NP_860558.1 similar to Escherichia coli YfcA; predicted membrane-associated NP_860559.1 predicted secreted protein NP_860561.1 predicted secreted protein NP_860562.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_860564.1 similar to Escherichia coli Z0347; predicted secreted protein NP_860565.1 predicted oxidoreductase NP_860567.1 predicted secreted protein NP_860569.1 modification methylase NP_860573.1 predicted transcriptional regulator NP_860576.1 predicted secreted protein NP_860577.1 predicted acetyltransferase NP_860580.1 predicted secreted protein NP_860581.1 similar to Helicobacter pylori ulcer associated adenine specific DNA methyltransferase IceA NP_860582.1 similar to Neisseria lactamica type II restriction endonuclease NP_860585.1 similar to Listeria monocytogenes LMO2438 NP_860587.1 similar to Campylobacter jejuni CJ1556 NP_860588.1 similar to Campylobacter jejuni CJ1555c NP_860589.1 predicted membrane-associated NP_860590.1 predicted membrane-associated NP_860591.1 similar to Listeria monocytogenes LMO2083 NP_860592.1 similar to Helicobacter pylori JHP0572 NP_860594.1 similar to Bacillus subtilis aminoglycoside 6-adenyltransferase AAD(6) NP_860595.1 predicted membrane-associated NP_860596.1 predicted membrane-associated NP_860597.1 similar to Helicobacter pylori JHP0907; predicted secreted protein NP_860598.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_860599.1 similar to Helicobacter pylori HP1486 NP_860601.1 predicted membrane-associated NP_860602.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_860603.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_860605.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen NP_860607.1 similar to Helicobacter pylori HP0716 NP_860608.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_860610.1 similar to Campylobacter jejuni CJ0593c; predicted membrane-associated NP_860612.1 makes up the distal portion of the flagellar basal body rod NP_860613.1 similar to Campylobacter jejuni CJ0609c NP_860614.1 similar to Campylobacter jejuni periplasmic protein CJ0610c NP_860615.1 predicted membrane-associated NP_860616.1 predicted membrane-associated NP_860617.1 similar to Xylella fastidiosa XF1738; predicted membrane-associated NP_860618.1 possible transcriptional regulator NP_860619.1 similar to Campylobacter jejuni methyl-accepting chemotaxis signal transduction protein CJ1564 NP_860621.1 similar to HP1092 (FlgG1/FlgF) NP_860622.1 modification subunit NP_860624.1 similar to Helicobacter pylori HP1221 NP_860628.1 predicted secreted protein NP_860629.1 similar to Helicobacter pylori HP1507 NP_860630.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis NP_860632.1 predicted membrane-associated NP_860633.1 subunit II NP_860634.1 subunit I NP_860635.1 similar to Campylobacter jejuni CJ0080 NP_860636.1 similar to Campylobacter jejuni CJ0411; predicted ATP/GTP binding protein NP_860637.1 similar to Campylobacter jejuni CJ0412; predicted ATP/GTP binding protein NP_860638.1 predicted secreted protein NP_860640.1 similar to Campylobacter jejuni efflux protein CJ1687 NP_860641.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_860642.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity NP_860643.1 predicted membrane-associated NP_860644.1 predicted membrane-associated NP_860645.1 predicted secreted protein NP_860646.1 similar to Neisseria meningitidis pilin PilQ NP_860647.1 similar to Neisseria meningitidis pilin PilT NP_860648.1 similar to Neisseria meningitidis pilin PilG NP_860651.2 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor NP_860653.1 similar to Helicobacter pylori HP1464; predicted membrane-associated NP_860654.1 ATP-binding component NP_860655.1 similar to Helicobacter pylori HP1466; predicted ABC transporter NP_860656.1 predicted membrane-associated NP_860657.1 binds the polymerase to DNA and acts as a sliding clamp NP_860658.1 negatively supercoils closed circular double-stranded DNA NP_860659.1 predicted secreted protein NP_860660.1 may become fused with HH1130 due to slipped strand mispairing NP_860661.1 may become fused with HH1129 due to slipped strand mispairing NP_860662.1 predicted membrane-associated NP_860664.1 predicted secreted protein NP_860666.1 small subunit NP_860667.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis NP_860671.1 Important for the balance of metabolites in the pentose-phosphate pathway NP_860672.1 similar to Helicobacter pylori HP0231; possible protein disulfide isomerase NP_860674.1 positive regulator of class III flagellar genes NP_860675.1 similar to Helicobacter pylori HP1034; predicted ATP-binding protein NP_860676.1 similar to Helicobacter pylori JHP0391; predicted membrane-associated NP_860677.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes NP_860678.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation NP_860679.1 One of three proteins involved in switching the direction of the flagellar rotation NP_860680.1 predicted membrane-associated NP_860683.1 predicted membrane-associated NP_860684.1 similar to Helicobacter pylori HP1164; predicted thioredoxin reductase NP_860685.1 similar to Helicobacter pylori HP1163; predicted secreted protein NP_860686.1 similar to methyl-accepting chemotaxis proteins NP_860687.1 catalyzes branch migration in Holliday junction intermediates NP_860689.1 predicted secreted protein NP_860690.1 similar to Pseudomonas aeruginosa PA1689; predicted membrane-associated NP_860692.1 similar to Campylobacter jejuni integral membrane protein NP_860693.1 similar to Helicobacter pylori JHP1206; predicted secreted protein NP_860694.1 predicted transcriptional regulator NP_860696.1 similar to Helicobacter pylori HP0022; predicted membrane-associated NP_860698.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_860699.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_860700.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate NP_860701.1 similar to Campylobacter jejuni integral membrane protein CJ1356c NP_860703.1 similar to Helicobacter pylori capsule biosynthesis protein KpsF (HP1429) NP_860704.1 similar to Helicobacter pylori HP1430 NP_860705.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_860708.1 similar to Helicobacter pylori HP1530 NP_860709.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_860710.1 predicted membrane-associated NP_860711.1 similar to Helicobacter pylori HP0100 NP_860712.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP NP_860713.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis NP_860714.1 binds and unfolds substrates as part of the ClpXP protease NP_860715.1 functions in MreBCD complex in some organisms NP_860716.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_860718.1 predicted secreted protein NP_860720.1 similar to Campylobacter jejuni CJ0021c; predicted isomerase NP_860721.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme NP_860722.1 predicted membrane-associated NP_860723.1 predicted secreted protein NP_860724.1 similar to Campylobacter jejuni coiled-coil protein NP_860725.1 similar to Helicobacter pylori HP1391; predicted membrane-associated NP_860726.1 predicted secreted protein NP_860729.1 similar to Campylobacter jejuni CJ1633 NP_860730.2 synthesizes RNA primers at the replication forks NP_860731.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_860732.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_860735.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_860736.1 predicted Na+ or K+ uptake protein NP_860737.1 predicted potassium uptake protein NP_860738.1 predicted biotin biosynthesis protein BioC NP_860739.1 similar to Campylobacter jejuni CJ0305c; predicted membrane-associated NP_860741.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate NP_860743.1 similar to Pseudomonas aeruginosa PA3954 NP_860745.1 similar to Bacillus halodurans BH0835 NP_860746.1 similar to Pseudomonas aeruginosa PA2326 NP_860747.1 predicted secreted protein NP_860748.1 predicted secreted protein NP_860750.1 similar to Helicobacter pylori JHP0437; predicted catalase-like protein NP_860751.1 similar to Vibrio cholerae VCA0834; predicted membrane-associated NP_860752.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_860753.1 similar to Helicobacter pylori JHP0197; predicted secreted protein NP_860755.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell NP_860757.1 similar to Campylobacter jejuni periplasmic protein CJ0633 NP_860758.1 possibly involved in DNA uptake NP_860759.1 predicted membrane-associated NP_860760.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_860761.1 similar to Campylobacter jejuni integral membrane protein NP_860762.1 predicted secreted protein NP_860763.1 similar to Campylobacter jejuni CJ0121 NP_860764.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis NP_860766.1 similar to Helicobacter pylori HP0948; predicted membrane-associated NP_860768.2 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA NP_860769.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits NP_860770.1 similar to Campylobacter jejuni CJ0128c; predicted extragenic suppressor protein SuhB NP_860771.1 similar to Helicobacter pylori HP0951 NP_860772.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer NP_860776.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_860777.1 predicted secreted protein NP_860778.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_860779.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_860780.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_860782.1 similar to Campylobacter jejuni CJ0846; predicted membrane-associated NP_860783.1 similar to Campylobacter jejuni CJ0343c; predicted membrane-associated NP_860785.1 similar to Campylobacter jejuni CJ1613c NP_860786.1 similar to Helicobacter pylori HP0728; predicted PP-loop superfamily ATPase NP_860787.1 CcoN; FixN NP_860788.1 CcoO; FixO NP_860791.1 similar to Campylobacter jejuni periplasmic protein NP_860792.1 predicted membrane-associated NP_860793.1 similar to Helicobacter pylori HP0149; predicted secreted protein NP_860794.1 predicted secreted protein NP_860795.1 predicted secreted protein NP_860798.1 similar to Campylobacter jejuni CJ1687; predicted efflux protein NP_860799.1 similar to Helicobacter pylori HP1222; predicted D-lactate dehydrogenase Dld NP_860800.1 similar to Campylobacter jejuni CJ0950c; predicted secreted protein NP_860801.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_860802.1 predicted secreted protein NP_860803.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_860804.1 similar to Campylobacter jejuni CJ0459c NP_860805.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_860806.1 similar to Helicobacter pylori HP0270 NP_860808.1 similar to Helicobacter pylori HP0272; predicted secreted protein NP_860809.1 predicted membrane-associated NP_860810.1 similar to Helicobacter pylori HP0707 NP_860811.1 similar to Campylobacter jejuni CJ0692c; predicted membrane-associated NP_860814.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine NP_860815.1 similar to Campylobacter jejuni CJ1002c NP_860816.1 similar to Neisseria meningitidis pilin PilE NP_860817.1 similar to Campylobacter jejuni CJ1467 NP_860818.1 similar to Helicobacter pylori HP1489; predicted secreted protein NP_860819.1 similar to Helicobacter pylori HP1488; predicted secreted protein NP_860820.1 required for 70S ribosome assembly NP_860821.1 similar to Helicobacter pylori HP0490; predicted potassium channel NP_860822.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_860827.1 possible kinase NP_860828.1 predicted secreted protein NP_860829.1 similar to Campylobacter jejuni integral membrane protein NP_860830.1 similar to Campylobacter jejuni CJ1501 NP_860835.1 similar to Helicobacter pylori Hop-family proteins NP_860836.1 predicted secreted protein NP_860837.1 similar to Helicobacter pylori HP1336 NP_860838.1 similar to Archaeoglobus fulgidus AF2335 NP_860839.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_860842.1 similar to Campylobacter jejuni CJ1454c NP_860843.1 predicted secreted protein NP_860844.1 Catalyzes a key regulatory step in fatty acid biosynthesis NP_860845.1 predicted secreted protein NP_860846.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_860848.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_860850.1 similar to Helicobacter pylori HP1487; predicted membrane-associated NP_860851.1 similar to Helicobacter pylori HP1575 (FlhB2) NP_860852.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_860854.1 similar to Helicobacter pylori HP1572; possibly regulatory protein DniR NP_860856.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_860857.1 similar to Helicobacter pylori HP1570 NP_860858.1 predicted secreted protein NP_860859.1 similar to Helicobacter pylori HP1568; predicted membrane-associated NP_860860.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential NP_860861.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate NP_860862.1 predicted membrane-associated NP_860866.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine NP_860867.1 similar to Helicobacter pylori HP0842 NP_860868.1 similar to Campylobacter jejuni MCP-type signal transduction protein CJ1506c NP_860869.1 similar to Campylobacter jejuni CJ0977 NP_860871.1 similar to Campylobacter jejuni CJ0976; predicted methyltransferase NP_860872.1 similar to Helicobacter pylori HP0418 NP_860873.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_860874.1 similar to Helicobacter pylori HP1384 NP_860875.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate NP_860877.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_860878.1 3'-5' exonuclease of DNA polymerase III NP_860881.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_860883.1 similar to Campylobacter jejuni CJ1056c NP_860884.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_860885.1 similar to Helicobacter pylori conserved hypothetical mitochondrial protein 4 NP_860886.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_860888.1 similar to Helicobacter pylori HP1028; predicted secreted protein NP_860890.1 required for the assembly of the flagellar basal body P-ring NP_860891.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate NP_860892.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_860893.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_860895.1 FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions NP_860896.1 predicted secreted protein NP_860897.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_860899.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_860900.1 similar to Campylobacter jejuni membrane protein NP_860901.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_860902.1 similar to Helicobacter pylori HP0571; predicted membrane-associated NP_860903.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_860904.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_860908.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_860909.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_860910.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_860911.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_860912.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_860913.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_860914.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_860915.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_860916.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_860917.1 one of the stabilizing components for the large ribosomal subunit NP_860918.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_860919.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_860920.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_860921.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_860922.1 similar to Helicobacter pylori JHP1226 NP_860923.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_860924.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_860925.1 binds 5S rRNA along with protein L5 and L25 NP_860926.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_860927.1 late assembly protein NP_860928.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_860929.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_860930.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_860931.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_860932.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_860933.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_860934.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_860935.1 is a component of the macrolide binding site in the peptidyl transferase center NP_860937.1 predicted secreted protein NP_860938.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella NP_860939.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod NP_860940.1 forms a junction between the M-ring and FlgB during flagella biosynthesis NP_860941.1 probable penicillin-binding protein NP_860943.1 similar to Helicobacter pylori JHP0216 NP_860944.1 predicted membrane-associated NP_860945.1 alpha chain NP_860946.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_860947.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; a fusion protein of this enzyme with MsrA and thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae NP_860948.1 predicted secreted protein NP_860953.1 similar to Neisseria meningitidis NMA1635 NP_860954.1 methyltransferase subunit NP_860955.1 possible arsenical pump membrane protein NP_860957.1 similar to Campylobacter jejuni CJ1420c NP_860958.1 possible methyltransferase NP_860963.1 predicted secreted protein NP_860966.1 possible restriction/modification enzyme NP_860967.1 similar to Campylobacter jejuni CJ1418c NP_860968.1 similar to Campylobacter jejuni CJ1417c NP_860969.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis NP_860970.1 possible sugar nucleotidyltransferase NP_860971.1 probable CysQ protein homolog NP_860972.1 similar to Campylobacter jejuni CJ1137c NP_860973.1 similar to Campylobacter jejuni CJ0140 NP_860976.1 similar to Helicobacter pylori type II DNA modification enzyme JHP0045 NP_860982.1 possible cation efflux pump NP_860983.1 possible cation efflux pump NP_860985.1 similar to Listeria monocytogenes antibiotic resistance protein LMO0872 NP_860986.1 predicted membrane-associated NP_860987.1 predicted membrane-associated NP_860988.1 predicted membrane-associated NP_860989.1 predicted membrane-associated NP_860991.1 similar to yersinia pestis YP1998; predicted secreted protein NP_860992.1 predicted secreted protein NP_860994.1 similar to Bacillus halodurans BH0306 NP_860995.1 similar to Pseudomonas aeruginosa PA1316; predicted efflux transporter NP_860998.1 predicted secreted protein NP_860999.1 similar to Lactococcus lactis gamma-carboxymuconolactone decarboxylase NP_861000.1 possible galactoside acyltransferase NP_861001.1 predicted secreted protein NP_861004.1 predicted secreted protein NP_861005.1 similar to Bacteroides vulgaris nitroimidazole antibiotic resistance protein NP_861006.1 predicted membrane-associated NP_861007.1 similar to Campylobacter jejuni CJ1523c NP_861009.1 similar to Escherichia coli HybA hydrogenase NP_861010.1 similar to Vibrio cholerae VC1511; predicted hydrogenase cytochrome B component NP_861011.1 ATP-binding protein NP_861012.1 PEB1 NP_861015.1 similar to Campylobacter jejuni HP1065 NP_861016.1 predicted membrane-associated NP_861017.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_861018.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step NP_861020.1 mediates the export of protein precursors bearing twin-arginine signal peptides NP_861021.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_861022.1 similar to Helicobacter pylori HP1479; predicted membrane-associated NP_861024.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH NP_861025.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_861026.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_861027.1 similar to Helicobacter pylori HP1498; predicted membrane-associated NP_861028.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_861029.1 similar to Aquifex aeolicus thiamine phosphate synthase AQ1366 NP_861030.1 similar to Campylobacter jejuni integral membrane protein CJ1055c NP_861031.1 predicted membrane-associated NP_861032.1 similar to Helicobacter pylori HP0945; predicted secreted protein NP_861033.1 similar to Bacillus halodurans BH0857; predicted secreted protein NP_861034.1 similar to Campylobacter jejuni CJ0522; predicted membrane-associated NP_861035.1 similar to Campylobacter jejuni CJ0937; predicted integral membrane protein NP_861037.1 predicted secreted protein NP_861040.1 similar to Helicobacter pylori JHP0277 NP_861041.1 similar to Streptomyces globisporus lysozyme M1 precursor NP_861044.1 similar to Mycobacterium tuberculosis Rv1679; predicted acyl-CoA dehydrogenase NP_861045.1 similar to Mycobacterium tuberculosis Rv1680 NP_861046.1 catalyzes the modification of U13 in tRNA(Glu) NP_861047.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer NP_861049.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_861053.1 predicted secreted protein NP_861054.1 predicted secreted protein NP_861055.1 predicted membrane-associated NP_861056.1 predicted secreted protein NP_861057.1 predicted secreted protein NP_861058.1 predicted secreted protein NP_861060.1 similar to Clostridium acetobutylicum CAC2401; predicted activator of 2-hydroxyglutaryl-CoA dehydratase NP_861061.1 predicted membrane-associated NP_861063.1 similar to Campylobacter jejuni ADP-heptose synthase NP_861065.1 phosphatase NP_861066.1 similar to Campylobacter jejuni CJ1493c; predicted membrane-associated NP_861067.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_861070.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_861071.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_861073.1 predicted secreted protein NP_861074.1 similar to Helicobacter pylori Hop-family proteins NP_861076.1 predicted membrane-associated NP_861077.1 similar to Pseudomonas aeruginosa PA3235; predicted membrane-associated NP_861078.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake NP_861079.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_861080.1 similar to Campylobacter jejuni CJ0681 NP_861081.1 similar to Helicobacter pylori HP0386 NP_861082.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_861083.1 similar to Campylobacter jejuni CJ1460 NP_861084.1 DNA methylase NP_861085.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring NP_861086.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_861087.1 predicted secreted protein NP_861091.1 similar to Pseudomonas aeruginosa PA1116 NP_861094.1 possible ATP/GTP-binding protein NP_861095.1 ATP-binding subunit NP_861096.1 similar to Neisseria meningitidis NMB0837 NP_861098.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates NP_861099.1 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin NP_861100.1 Couples the complete acetyl-CoA oxidation to aromatic ring reduction by the use of the low-potential electron shuttle ferredoxin NP_861103.1 similar to Helicobacter pylori aminodeoxychorismate lyase HP0587 NP_861104.1 predicted secreted protein NP_861105.1 similar to Campylobacter jejuni CJ1397 NP_861108.1 One of three proteins involved in switching the direction of the flagellar rotation NP_861109.1 predicted membrane-associated NP_861110.1 similar to Helicobacter pylori HP0582; TonB-like NP_861112.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_861113.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations NP_861114.1 similar to Campylobacter jejuni possible two-component response regulator CJ1608 NP_861116.1 predicted secreted protein NP_861121.1 Catalyzes the transfer of electrons from NADH to quinone NP_861122.1 Catalyzes the transfer of electrons from NADH to quinone NP_861123.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_861124.1 Catalyzes the transfer of electrons from NADH to quinone NP_861125.1 Catalyzes the transfer of electrons from NADH to quinone NP_861126.1 Catalyzes the transfer of electrons from NADH to quinone NP_861127.1 Catalyzes the transfer of electrons from NADH to quinone NP_861128.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_861129.1 similar to Helicobacter pylori HP1265; predicted donor-ubiquinone reductase I NP_861130.1 similar to Helicobacter pylori 1264; predicted donor-ubiquinone reductase I NP_861131.1 Catalyzes the transfer of electrons from NADH to quinone NP_861132.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_861133.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen NP_861134.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_861135.2 similar to Helicobacter pylori HP0162 NP_861137.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_861139.1 BaeR-like NP_861142.1 similar to Campylobacter jejuni CJ0787 NP_861143.1 similar to Helicobacter pylori HP1182 NP_861144.1 predicted membrane-associated NP_861145.1 similar to Helicobacter pylori HP1181; predicted efflux transporter NP_861147.1 similar to Helicobacter pylori HP1440 NP_861150.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_861151.1 predicted PurS-like protein NP_861152.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_861153.1 similar to Helicobacter pylori JHP1268; predicted membrane-associated NP_861155.1 Catalyzes (S)-dihydroorotate + O(2) = orotate + H(2)O(2) in the pyrimidine biosynthesis pathway NP_861157.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_861158.1 Acts on the hydroxyl group at position 7 of the steroid frame NP_861159.1 Transfers the fatty acyl group on membrane lipoproteins NP_861160.1 predicted secreted protein NP_861161.1 similar to Campylobacter jejuni CJ1679 NP_861163.1 similar to Escherichia coli YeaS; predicted membrane-associated NP_861164.1 negatively supercoils closed circular double-stranded DNA NP_861165.1 predicted secreted protein NP_861167.1 predicted secreted protein NP_861168.1 similar to Vibrio cholerae VC0271; predicted membrane-associated NP_861169.1 similar to Vibrio cholerae VC0271; predicted membrane-associated NP_861170.1 predicted secreted protein NP_861171.1 similar to Helicobacter pylori HP1026 NP_861175.1 similar to Helicobacter pylori NA(+)/H(+) antiporter 1 jhp1447 NP_861176.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH NP_861177.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex NP_861178.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane NP_861179.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_861180.1 similar to Helicobacter pylori conserved hypothetical integral membrane protein NP_861182.1 predicted secreted protein NP_861183.1 similar to Campylobacter jejuni hydrolase NP_861184.1 FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions NP_861185.1 similar to Escherichia coli YfcA; predicted membrane-associated NP_861186.1 similar to Helicobacter pylori HP0721; predicted secreted protein NP_861187.1 similar to Campylobacter jejuni chemotaxis two-component response regulator CJ1223c NP_861188.1 similar to Campylobacter jejuni chemotaxis two-component histidine kinase CJ1222c NP_861189.1 unwinds double stranded DNA NP_861190.1 similar to Helicobacter pylori competence protein ComE3 NP_861191.1 possible UDP-glucose 6-dehydrogenase NP_861192.1 possible acyltransferase NP_861194.1 similar to Campylobacter jejuni CJ0404; predicted transmembrane protein NP_861195.1 similar to Helicobacter pylori HP0184 NP_861196.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_861197.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_861198.1 similar to Helicobacter pylori HP0181; predicted membrane-associated NP_861199.1 UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin NP_861201.1 similar to Helicobacter pylori HP1358; predicted membrane-associated NP_861202.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_861203.1 similar to Helicobacter pylori HP0580; predicted membrane-associated NP_861204.1 predicted membrane-associated NP_861205.1 similar to Helicobacter pylori HP0578; predicted membrane-associated NP_861207.1 similar to Helicobacter pylori Hop-family proteins; may become fused with HH1677 due to slipped strand mispairing NP_861208.1 similar to Helicobacter pylori Hop-family proteins; may become fused with HH1676 due to slipped strand mispairing NP_861209.1 similar to Campylobacter jejuni CJ0186c; predicted membrane-associated NP_861212.1 similar to Campylobacter jejuni CJ1068; predicted metallopeptidase NP_861213.1 similar to Helicobacter pylori HP0395 NP_861214.1 predicted secreted protein NP_861216.1 similar to Campylobacter jejuni CJ0984 NP_861217.1 catalyzes the formation of oxaloacetate from pyruvate NP_861219.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_861220.1 predicted membrane-associated NP_861221.1 predicted membrane-associated NP_861222.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine NP_861223.1 similar to Helicobacter pylori HP1435; predicted protease NP_861224.1 similar to Campylobacter jejuni CJ1388 NP_861225.1 predicted secreted protein NP_861226.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook NP_861228.1 similar to Campylobacter jejuni chemotaxis two-component response regulator CJ0355c NP_861230.2 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine NP_861231.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_861232.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_861233.1 similar to Campylobacter jejuni CJ0667 NP_861234.1 similar to Helicobacter pylori JHP0852 NP_861235.1 the hook connects flagellar basal body to the flagellar filament NP_861236.1 similar to Campylobacter jejuni possible periplasmic protein NP_861237.1 similar to Helicobacter pylori JHP0273; predicted membrane-associated NP_861238.1 FAD/NAD(P)-binding domain NP_861240.1 similar to Campylobacter jejuni CiaB protein NP_861242.1 metalloprotease NP_861243.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_861244.1 similar to Helicobacter pylori Hop-family proteins NP_861245.1 similar to Deinococcus radiodurans histidinol phosphatase DR0470 NP_861247.1 similar to Helicobacter pylori HP1485 NP_861248.1 similar to Helicobacter pylori HP1484; predicted membrane-associated NP_861249.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_861250.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_861251.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate NP_861252.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_861253.1 similar to Campylobacter jejuni CJ0539 NP_861254.1 similar to Helicobacter pylori HP0242 NP_861255.1 possible geranyl transferase NP_861256.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_861257.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_861258.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_861260.1 similar to Helicobacter pylori Hop-family proteins NP_861262.1 catalyzes the formation of biotin from dethiobiotin and sulfur NP_861263.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_861267.1 similar to Campylobacter jejuni CJ1505c NP_861268.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate NP_861269.1 predicted membrane-associated NP_861270.1 similar to Helicobacter pylori HP0405; predicted NifS-like protein NP_861271.1 molecular chaperone NP_861272.1 similar to Campylobacter jejuni CJ1618c NP_861273.1 predicted secreted protein NP_861274.1 predicted secreted protein NP_861275.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_861277.1 possible rRNA methylase NP_861278.1 predicted membrane-associated NP_861279.1 similar to Helicobacter pylori HP0555; predicted secreted protein NP_861280.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_861281.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_861282.1 similar to Helicobacter pylori HP0823 NP_861286.1 predicted secreted protein NP_861288.1 similar to Helicobacter pylori HP0085; predicted secreted protein NP_861289.1 similar to Campylobacter jejuni CJ0141c; possible ABC transporter NP_861290.1 ATP-binding protein NP_861291.1 similar to Campylobacter jejuni CJ0143c; predicted periplasmic solute binding protein for ABC transport system NP_861292.1 similar to Helicobacter pylori HP0087; predicted secreted protein NP_861293.1 similar to Campylobacter jejuni CJ0717 NP_861295.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline NP_861296.1 similar to Helicobacter pylori HP0983; predicted membrane-associated NP_861297.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides NP_861301.1 similar to Helicobacter pylori JHP0739; predicted membrane-associated NP_861302.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_861304.1 similar to Helicobacter pylori HP0642 (FrxA); predicted nitroreductase NP_861305.1 Catalyzes the rate-limiting step in dNTP synthesis NP_861306.1 predicted membrane-associated NP_861308.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_861309.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_861310.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_861311.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_861312.1 predicted secreted protein NP_861313.1 predicted secreted protein NP_861314.1 similar to Campylobacter jejuni CJ0916c NP_861315.1 permease OppB NP_861316.1 permease OppC NP_861317.1 ATP-binding protein OppD NP_861320.1 predicted membrane-associated NP_861321.1 predicted secreted protein NP_861323.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid NP_861324.1 beta subunit NP_861326.1 similar to Campylobacter jejuni CJ1337; predicted secreted protein NP_861327.1 FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions NP_861329.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_861330.1 similar to Helicobacter pylori Hop-family proteins NP_861331.1 similar to Thermotoga maritima TM0763 NP_861332.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_861333.1 similar to Helicobacter pylori HP0616 (CheV2) NP_861334.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_861335.1 similar to Helicobacter pylori HP1029 NP_861336.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. NP_861338.1 similar to Pseudomonas aeruginosa PA1644 NP_861340.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_861342.1 similar to Campylobacter jejuni CJ1100 NP_861343.1 similar to Helicobacter pylori JHP0420 NP_861344.1 similar to Helicobacter pylori JHP0420 NP_861345.1 similar to Helicobacter pylori HP0467; predicted membrane-associated NP_861346.1 similar to Helicobacter pylori HP0466 NP_861348.1 similar to Campylobacter jejuni CJ0436 NP_861350.1 phosphate starvation-inducible protein PhoH NP_861351.1 predicted membrane-associated NP_861352.1 predicted lipoprotein NP_861353.1 similar to Campylobacter jejuni CJ1429c; may become fused with HH1823 due to slipped strand mispairing NP_861354.1 similar to Campylobacter jejuni CJ1429c; may become fused with HH1822 due to slipped strand mispairing NP_861355.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_861356.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_861357.1 predicted secreted protein NP_861358.1 similar to Helicobacter pylori HP0235 NP_861360.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate NP_861362.1 similar to Helicobacter pylori HP0117 NP_861364.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide NP_861365.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP NP_861366.1 similar to Campylobacter jejuni CJ1374c NP_861367.1 predicted membrane-associated NP_861368.1 predicted membrane-associated NP_861369.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine NP_861370.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_861371.1 predicted membrane-associated NP_861373.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_861374.1 similar to Campylobacter jejuni CJ0949c NP_861377.1 similar to Helicobacter pylori HP1580; predicted membrane-associated NP_861379.1 catalyzes the hydrolysis of pyrophosphate NP_861380.1 biotin carboxylase; catalyses the carboxylation of the carrier protein which then transfers the carboxyl group to form malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_861381.1 similar to Helicobacter pylori HP1363 NP_861382.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_861383.1 similar to Campylobacter jejuni CJ0590 NP_861386.1 similar to Escherichia coli ECS2092; predicted secreted protein NP_861387.1 ATP-binding component NP_861388.1 ATP-binding component NP_861389.1 similar to Campylobacter jejuni CJ0606; predicted membrane-associated NP_861390.1 similar to Campylobacter jejuni CJ0364c; predicted outer membrane channel protein NP_861392.1 similar to Helicobacter pylori JHP0016 NP_861393.1 similar to Helicobacter pylori HP1457 NP_861394.1 similar to Helicobacter pylori HP1456; predicted lipoprotein NP_861395.1 predicted secreted protein NP_861396.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_861397.1 similar to Helicobacter pylori HP1493 NP_861398.1 similar to Helicobacter pylori HP1492; predicted NifU-like protein NP_861400.1 similar to Wolinella succinogenes small integral C4-dicarboxylate membrane transport protein NP_861401.1 similar to Wolinella succinogenes large integral C4-dicarboxylate membrane transport protein NP_861403.1 similar to Helicobacter pylori HP1490; predicted membrane-associated NP_861404.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_861405.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde