-- dump date   	20140619_112055
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1002804000001	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804000002	Sel1 repeat; Region: Sel1; cl02723
1002804000003	Initiator Replication protein; Region: Rep_3; pfam01051
1002804000004	Fic family protein [Function unknown]; Region: COG3177
1002804000005	Fic/DOC family; Region: Fic; pfam02661
1002804000006	hypothetical protein; Provisional; Region: PRK11281
1002804000007	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
1002804000008	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1002804000009	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1002804000010	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1002804000011	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1002804000012	active site
1002804000013	catalytic tetrad [active]
1002804000014	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1002804000015	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1002804000016	active site
1002804000017	catalytic tetrad [active]
1002804000018	potential frameshift: common BLAST hit: gi|315124974|ref|YP_004066978.1| putative transcriptional regulator
1002804000019	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1002804000020	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1002804000021	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1002804000022	DNA binding residues [nucleotide binding]
1002804000023	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1002804000024	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1002804000025	catalytic residues [active]
1002804000026	catalytic nucleophile [active]
1002804000027	Presynaptic Site I dimer interface [polypeptide binding]; other site
1002804000028	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1002804000029	Synaptic Flat tetramer interface [polypeptide binding]; other site
1002804000030	Synaptic Site I dimer interface [polypeptide binding]; other site
1002804000031	DNA binding site [nucleotide binding]
1002804000032	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1002804000033	Domain of unknown function(DUF2779); Region: DUF2779; pfam11074
1002804000034	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1002804000035	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000036	Walker A motif; other site
1002804000037	ATP binding site [chemical binding]; other site
1002804000038	Walker B motif; other site
1002804000039	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1002804000040	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1002804000041	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1002804000042	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1002804000043	ATP binding site [chemical binding]; other site
1002804000044	putative Mg++ binding site [ion binding]; other site
1002804000045	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1002804000046	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1002804000047	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1002804000048	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1002804000049	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1002804000050	PemK-like protein; Region: PemK; cl00995
1002804000051	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1002804000052	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1002804000053	ParA-like protein; Provisional; Region: PHA02518
1002804000054	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1002804000055	P-loop; other site
1002804000056	Magnesium ion binding site [ion binding]; other site
1002804000057	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1002804000058	Fic/DOC family; Region: Fic; cl00960
1002804000059	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1002804000060	HipA N-terminal domain; Region: Couple_hipA; cl11853
1002804000061	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1002804000062	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1002804000063	Fic family protein [Function unknown]; Region: COG3177
1002804000064	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
1002804000065	Fic/DOC family; Region: Fic; pfam02661
1002804000066	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
1002804000067	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1002804000068	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1002804000069	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1002804000070	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1002804000071	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804000072	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1002804000073	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1002804000074	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1002804000075	HupF/HypC family; Region: HupF_HypC; pfam01455
1002804000076	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1002804000077	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804000078	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1002804000079	Walker A/P-loop; other site
1002804000080	ATP binding site [chemical binding]; other site
1002804000081	Q-loop/lid; other site
1002804000082	ABC transporter signature motif; other site
1002804000083	Walker B; other site
1002804000084	D-loop; other site
1002804000085	H-loop/switch region; other site
1002804000086	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1002804000087	Protein of unknown function (DUF507); Region: DUF507; pfam04368
1002804000088	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1002804000089	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1002804000090	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1002804000091	catalytic site [active]
1002804000092	subunit interface [polypeptide binding]; other site
1002804000093	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804000094	Sel1 repeat; Region: Sel1; cl02723
1002804000095	Sel1 repeat; Region: Sel1; cl02723
1002804000096	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
1002804000097	NusA N-terminal domain; Region: NusA_N; pfam08529
1002804000098	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1002804000099	RNA binding site [nucleotide binding]; other site
1002804000100	homodimer interface [polypeptide binding]; other site
1002804000101	NusA-like KH domain; Region: KH_5; pfam13184
1002804000102	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1002804000103	G-X-X-G motif; other site
1002804000104	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1002804000105	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1002804000106	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1002804000107	C-terminal peptidase (prc); Region: prc; TIGR00225
1002804000108	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1002804000109	protein binding site [polypeptide binding]; other site
1002804000110	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1002804000111	Catalytic dyad [active]
1002804000112	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1002804000113	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1002804000114	putative acyl-acceptor binding pocket; other site
1002804000115	ATP-dependent protease Clp, ATPase subunit [Posttranslational modification, protein turnover, chaperones]; Region: ClpX; COG1219
1002804000116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000117	Walker A motif; other site
1002804000118	ATP binding site [chemical binding]; other site
1002804000119	Walker B motif; other site
1002804000120	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; cl17398
1002804000121	potential frameshift: common BLAST hit: gi|315452784|ref|YP_004073054.1| tRNA pseudouridine synthase D, TruD
1002804000122	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1002804000123	active site
1002804000124	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1002804000125	RDD family; Region: RDD; pfam06271
1002804000126	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1002804000127	active site
1002804000128	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1002804000129	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1002804000130	hinge region; other site
1002804000131	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1002804000132	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1002804000133	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804000134	S-adenosylmethionine binding site [chemical binding]; other site
1002804000135	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1002804000136	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1002804000137	active site
1002804000138	HIGH motif; other site
1002804000139	dimer interface [polypeptide binding]; other site
1002804000140	KMSKS motif; other site
1002804000141	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1002804000142	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1002804000143	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1002804000144	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1002804000145	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804000146	dimer interface [polypeptide binding]; other site
1002804000147	conserved gate region; other site
1002804000148	ABC-ATPase subunit interface; other site
1002804000149	Bacterial SH3 domain; Region: SH3_3; pfam08239
1002804000150	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1002804000151	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1002804000152	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1002804000153	shikimate binding site; other site
1002804000154	NAD(P) binding site [chemical binding]; other site
1002804000155	putative acyltransferase; Provisional; Region: PRK05790
1002804000156	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1002804000157	dimer interface [polypeptide binding]; other site
1002804000158	active site
1002804000159	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1002804000160	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1002804000161	potential frameshift: common BLAST hit: gi|315452994|ref|YP_004073264.1| hydantoin hydantoinase A
1002804000162	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1002804000163	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1002804000164	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1002804000165	5-oxoprolinase; Region: PLN02666
1002804000166	potential frameshift: common BLAST hit: gi|315452995|ref|YP_004073265.1| putative Acetone carboxylase subunit gamma
1002804000167	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
1002804000168	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1002804000169	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1002804000170	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1002804000171	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
1002804000172	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
1002804000173	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
1002804000174	crystallin beta/gamma motif-containing protein; Region: PHA00657
1002804000175	Probable transposase; Region: OrfB_IS605; pfam01385
1002804000176	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1002804000177	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1002804000178	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
1002804000179	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1002804000180	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1002804000181	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
1002804000182	potential frameshift: common BLAST hit: gi|325298661|ref|YP_004258578.1| Type II site-specific deoxyribonuclease
1002804000183	HaeIII restriction endonuclease; Region: RE_HaeIII; pfam09556
1002804000184	HaeIII restriction endonuclease; Region: RE_HaeIII; pfam09556
1002804000185	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1002804000186	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
1002804000187	cofactor binding site; other site
1002804000188	DNA binding site [nucleotide binding]
1002804000189	substrate interaction site [chemical binding]; other site
1002804000190	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1002804000191	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1002804000192	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1002804000193	Electron transfer DM13; Region: DM13; cl02735
1002804000194	TPR repeat; Region: TPR_11; pfam13414
1002804000195	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804000196	binding surface
1002804000197	TPR motif; other site
1002804000198	TPR repeat; Region: TPR_11; pfam13414
1002804000199	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1002804000200	Sel1-like repeats; Region: SEL1; smart00671
1002804000201	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804000202	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804000203	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804000204	binding surface
1002804000205	TPR motif; other site
1002804000206	Sel1-like repeats; Region: SEL1; smart00671
1002804000207	Sel1 repeat; Region: Sel1; cl02723
1002804000208	Sel1-like repeats; Region: SEL1; smart00671
1002804000209	Cache domain; Region: Cache_1; pfam02743
1002804000210	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1002804000211	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000212	dimer interface [polypeptide binding]; other site
1002804000213	putative CheW interface [polypeptide binding]; other site
1002804000214	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
1002804000215	Ligand Binding Site [chemical binding]; other site
1002804000216	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1002804000217	FMN binding site [chemical binding]; other site
1002804000218	dimer interface [polypeptide binding]; other site
1002804000219	thiamine-phosphate pyrophosphorylase; Provisional; Region: PRK02615
1002804000220	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1002804000221	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1002804000222	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1002804000223	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1002804000224	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1002804000225	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1002804000226	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1002804000227	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1002804000228	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1002804000229	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1002804000230	Protein of unknown function (DUF465); Region: DUF465; cl01070
1002804000231	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1002804000232	HSP70 interaction site [polypeptide binding]; other site
1002804000233	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1002804000234	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1002804000235	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1002804000236	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1002804000237	23S rRNA interface [nucleotide binding]; other site
1002804000238	L3 interface [polypeptide binding]; other site
1002804000239	FliW protein; Region: FliW; cl00740
1002804000240	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1002804000241	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1002804000242	active site
1002804000243	homodimer interface [polypeptide binding]; other site
1002804000244	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804000245	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000246	dimer interface [polypeptide binding]; other site
1002804000247	putative CheW interface [polypeptide binding]; other site
1002804000248	Alginate lyase; Region: Alginate_lyase; pfam05426
1002804000249	potential frameshift: common BLAST hit: gi|315453464|ref|YP_004073734.1| outer membrane protein P1
1002804000250	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1002804000251	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1002804000252	LPP20 lipoprotein; Region: LPP20; cl15824
1002804000253	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
1002804000254	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1002804000255	ligand binding site [chemical binding]; other site
1002804000256	active site
1002804000257	UGI interface [polypeptide binding]; other site
1002804000258	catalytic site [active]
1002804000259	Protein of unknown function (DUF3897); Region: DUF3897; pfam13036
1002804000260	LPP20 lipoprotein; Region: LPP20; pfam02169
1002804000261	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1002804000262	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1002804000263	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1002804000264	dimer interface [polypeptide binding]; other site
1002804000265	ssDNA binding site [nucleotide binding]; other site
1002804000266	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1002804000267	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1002804000268	DNA polymerase III subunit delta; Validated; Region: PRK08487
1002804000269	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1002804000270	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
1002804000271	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
1002804000272	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
1002804000273	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1002804000274	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1002804000275	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1002804000276	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1002804000277	Protein of unknown function (DUF1804); Region: DUF1804; pfam08822
1002804000278	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
1002804000279	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804000280	DNA methylase; Region: N6_N4_Mtase; pfam01555
1002804000281	Lecithin retinol acyltransferase; Region: LRAT; pfam04970
1002804000282	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1002804000283	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1002804000284	NADP binding site [chemical binding]; other site
1002804000285	active site
1002804000286	putative substrate binding site [chemical binding]; other site
1002804000287	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1002804000288	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1002804000289	DNA binding site [nucleotide binding]
1002804000290	active site
1002804000291	FAD binding domain; Region: FAD_binding_4; pfam01565
1002804000292	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1002804000293	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1002804000294	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1002804000295	dimer interface [polypeptide binding]; other site
1002804000296	ADP-ribose binding site [chemical binding]; other site
1002804000297	active site
1002804000298	nudix motif; other site
1002804000299	metal binding site [ion binding]; metal-binding site
1002804000300	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1002804000301	Peptidase family M23; Region: Peptidase_M23; pfam01551
1002804000302	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
1002804000303	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
1002804000304	Domain of unknown function (DUF4332); Region: DUF4332; pfam14229
1002804000305	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1002804000306	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
1002804000307	Citrate synthase; Region: Citrate_synt; pfam00285
1002804000308	oxalacetate binding site [chemical binding]; other site
1002804000309	citrylCoA binding site [chemical binding]; other site
1002804000310	coenzyme A binding site [chemical binding]; other site
1002804000311	catalytic triad [active]
1002804000312	Initiator Replication protein; Region: Rep_3; pfam01051
1002804000313	aspartate aminotransferase; Provisional; Region: PRK05764
1002804000314	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1002804000315	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804000316	homodimer interface [polypeptide binding]; other site
1002804000317	catalytic residue [active]
1002804000318	biotin carboxylase; Validated; Region: PRK08462
1002804000319	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1002804000320	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1002804000321	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1002804000322	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
1002804000323	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1002804000324	carboxyltransferase (CT) interaction site; other site
1002804000325	biotinylation site [posttranslational modification]; other site
1002804000326	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1002804000327	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1002804000328	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1002804000329	protein binding site [polypeptide binding]; other site
1002804000330	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1002804000331	protein binding site [polypeptide binding]; other site
1002804000332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1002804000333	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1002804000334	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
1002804000335	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1002804000336	ATP binding site [chemical binding]; other site
1002804000337	substrate interface [chemical binding]; other site
1002804000338	flagellar motor protein MotA; Validated; Region: PRK08456
1002804000339	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1002804000340	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
1002804000341	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1002804000342	ligand binding site [chemical binding]; other site
1002804000343	LabA_like proteins; Region: LabA_like; cd06167
1002804000344	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1002804000345	putative metal binding site [ion binding]; other site
1002804000346	elongation factor P; Validated; Region: PRK00529
1002804000347	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1002804000348	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1002804000349	RNA binding site [nucleotide binding]; other site
1002804000350	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1002804000351	RNA binding site [nucleotide binding]; other site
1002804000352	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1002804000353	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1002804000354	intersubunit interface [polypeptide binding]; other site
1002804000355	active site
1002804000356	zinc binding site [ion binding]; other site
1002804000357	Na+ binding site [ion binding]; other site
1002804000358	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1002804000359	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1002804000360	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
1002804000361	CrcB-like protein; Region: CRCB; cl09114
1002804000362	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1002804000363	active site
1002804000364	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1002804000365	active site residue [active]
1002804000366	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1002804000367	FAD binding domain; Region: FAD_binding_4; pfam01565
1002804000368	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1002804000369	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1002804000370	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1002804000371	catalytic residue [active]
1002804000372	putative FPP diphosphate  binding site; other site
1002804000373	putative FPP binding hydrophobic cleft; other site
1002804000374	dimer interface [polypeptide binding]; other site
1002804000375	putative IPP diphosphate binding site; other site
1002804000376	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1002804000377	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1002804000378	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804000379	Walker A/P-loop; other site
1002804000380	ATP binding site [chemical binding]; other site
1002804000381	Q-loop/lid; other site
1002804000382	ABC transporter signature motif; other site
1002804000383	Walker B; other site
1002804000384	D-loop; other site
1002804000385	H-loop/switch region; other site
1002804000386	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1002804000387	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1002804000388	dimer interface [polypeptide binding]; other site
1002804000389	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1002804000390	catalytic triad [active]
1002804000391	peroxidatic and resolving cysteines [active]
1002804000392	hypothetical protein; Provisional; Region: PRK05834
1002804000393	intersubunit interface [polypeptide binding]; other site
1002804000394	active site
1002804000395	Zn2+ binding site [ion binding]; other site
1002804000396	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1002804000397	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1002804000398	putative NAD(P) binding site [chemical binding]; other site
1002804000399	putative substrate binding site [chemical binding]; other site
1002804000400	catalytic Zn binding site [ion binding]; other site
1002804000401	structural Zn binding site [ion binding]; other site
1002804000402	dimer interface [polypeptide binding]; other site
1002804000403	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1002804000404	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
1002804000405	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1002804000406	putative active site [active]
1002804000407	catalytic site [active]
1002804000408	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1002804000409	putative active site [active]
1002804000410	catalytic site [active]
1002804000411	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1002804000412	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1002804000413	putative substrate translocation pore; other site
1002804000414	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1002804000415	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1002804000416	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1002804000417	trimer interface [polypeptide binding]; other site
1002804000418	active site
1002804000419	UDP-GlcNAc binding site [chemical binding]; other site
1002804000420	lipid binding site [chemical binding]; lipid-binding site
1002804000421	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1002804000422	triosephosphate isomerase; Provisional; Region: PRK14565
1002804000423	substrate binding site [chemical binding]; other site
1002804000424	dimer interface [polypeptide binding]; other site
1002804000425	catalytic triad [active]
1002804000426	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
1002804000427	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
1002804000428	Iron-sulfur protein interface; other site
1002804000429	proximal heme binding site [chemical binding]; other site
1002804000430	distal heme binding site [chemical binding]; other site
1002804000431	dimer interface [polypeptide binding]; other site
1002804000432	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
1002804000433	L-aspartate oxidase; Provisional; Region: PRK06175
1002804000434	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1002804000435	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
1002804000436	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1002804000437	catalytic loop [active]
1002804000438	iron binding site [ion binding]; other site
1002804000439	Sm and related proteins; Region: Sm_like; cl00259
1002804000440	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1002804000441	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1002804000442	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1002804000443	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1002804000444	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1002804000445	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1002804000446	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1002804000447	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1002804000448	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1002804000449	IMP binding site; other site
1002804000450	dimer interface [polypeptide binding]; other site
1002804000451	interdomain contacts; other site
1002804000452	partial ornithine binding site; other site
1002804000453	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804000454	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804000455	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1002804000456	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1002804000457	active site
1002804000458	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1002804000459	dimer interface [polypeptide binding]; other site
1002804000460	substrate binding site [chemical binding]; other site
1002804000461	catalytic residues [active]
1002804000462	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1002804000463	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1002804000464	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1002804000465	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1002804000466	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1002804000467	homotrimer interaction site [polypeptide binding]; other site
1002804000468	putative active site [active]
1002804000469	Sporulation related domain; Region: SPOR; pfam05036
1002804000470	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
1002804000471	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1002804000472	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1002804000473	dimer interface [polypeptide binding]; other site
1002804000474	active site
1002804000475	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1002804000476	folate binding site [chemical binding]; other site
1002804000477	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1002804000478	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1002804000479	dimer interface [polypeptide binding]; other site
1002804000480	putative anticodon binding site; other site
1002804000481	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1002804000482	motif 1; other site
1002804000483	active site
1002804000484	motif 2; other site
1002804000485	motif 3; other site
1002804000486	Colicin V production protein; Region: Colicin_V; pfam02674
1002804000487	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1002804000488	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
1002804000489	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1002804000490	active site
1002804000491	catalytic triad [active]
1002804000492	dimer interface [polypeptide binding]; other site
1002804000493	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1002804000494	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1002804000495	Walker A/P-loop; other site
1002804000496	ATP binding site [chemical binding]; other site
1002804000497	Q-loop/lid; other site
1002804000498	ABC transporter signature motif; other site
1002804000499	Walker B; other site
1002804000500	D-loop; other site
1002804000501	H-loop/switch region; other site
1002804000502	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1002804000503	chlorohydrolase; Provisional; Region: PRK08418
1002804000504	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1002804000505	active site
1002804000506	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1002804000507	dihydroorotase; Provisional; Region: PRK08417
1002804000508	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1002804000509	active site
1002804000510	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1002804000511	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1002804000512	helicase 45; Provisional; Region: PTZ00424
1002804000513	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1002804000514	ATP binding site [chemical binding]; other site
1002804000515	Mg++ binding site [ion binding]; other site
1002804000516	motif III; other site
1002804000517	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1002804000518	nucleotide binding region [chemical binding]; other site
1002804000519	ATP-binding site [chemical binding]; other site
1002804000520	branched-chain amino acid aminotransferase; Validated; Region: PRK06606
1002804000521	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1002804000522	homodimer interface [polypeptide binding]; other site
1002804000523	substrate-cofactor binding pocket; other site
1002804000524	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804000525	catalytic residue [active]
1002804000526	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1002804000527	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1002804000528	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
1002804000529	flavodoxin FldA; Validated; Region: PRK09267
1002804000530	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
1002804000531	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
1002804000532	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1002804000533	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1002804000534	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1002804000535	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1002804000536	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1002804000537	RNA methyltransferase, RsmE family; Region: TIGR00046
1002804000538	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1002804000539	Predicted membrane protein [Function unknown]; Region: COG1511
1002804000540	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804000541	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1002804000542	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1002804000543	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1002804000544	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
1002804000545	motif 1; other site
1002804000546	dimer interface [polypeptide binding]; other site
1002804000547	active site
1002804000548	motif 2; other site
1002804000549	motif 3; other site
1002804000550	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1002804000551	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1002804000552	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1002804000553	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1002804000554	Putative zinc ribbon domain; Region: DUF164; pfam02591
1002804000555	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
1002804000556	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1002804000557	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1002804000558	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1002804000559	active site
1002804000560	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1002804000561	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804000562	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804000563	T5orf172 domain; Region: T5orf172; pfam10544
1002804000564	Adenine-specific methyltransferase EcoRI; Region: EcoRI_methylase; pfam13651
1002804000565	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1002804000566	NeuB family; Region: NeuB; pfam03102
1002804000567	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1002804000568	NeuB binding interface [polypeptide binding]; other site
1002804000569	putative substrate binding site [chemical binding]; other site
1002804000570	potential frameshift: common BLAST hit: gi|315452677|ref|YP_004072947.1| UDP-N-acetylglucosamine 2-epimerase
1002804000571	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1002804000572	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1002804000573	homodimer interface [polypeptide binding]; other site
1002804000574	active site
1002804000575	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1002804000576	ligand binding site; other site
1002804000577	tetramer interface; other site
1002804000578	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
1002804000579	SIR2-like domain; Region: SIR2_2; pfam13289
1002804000580	NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair]; Region: Lig; COG0272
1002804000581	Ycf46; Provisional; Region: ycf46; CHL00195
1002804000582	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000583	Walker A motif; other site
1002804000584	ATP binding site [chemical binding]; other site
1002804000585	Walker B motif; other site
1002804000586	arginine finger; other site
1002804000587	Phage-related protein [Function unknown]; Region: COG5412
1002804000588	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1002804000589	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
1002804000590	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1002804000591	homodimer interface [polypeptide binding]; other site
1002804000592	substrate-cofactor binding pocket; other site
1002804000593	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804000594	catalytic residue [active]
1002804000595	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1002804000596	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1002804000597	dimer interface [polypeptide binding]; other site
1002804000598	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804000599	catalytic residue [active]
1002804000600	GTP-binding protein LepA; Provisional; Region: PRK05433
1002804000601	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1002804000602	G1 box; other site
1002804000603	putative GEF interaction site [polypeptide binding]; other site
1002804000604	GTP/Mg2+ binding site [chemical binding]; other site
1002804000605	Switch I region; other site
1002804000606	G2 box; other site
1002804000607	G3 box; other site
1002804000608	Switch II region; other site
1002804000609	G4 box; other site
1002804000610	G5 box; other site
1002804000611	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1002804000612	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1002804000613	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1002804000614	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1002804000615	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
1002804000616	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718
1002804000617	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1002804000618	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
1002804000619	FAD binding domain; Region: FAD_binding_4; pfam01565
1002804000620	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1002804000621	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1002804000622	putative DNA binding site [nucleotide binding]; other site
1002804000623	putative Zn2+ binding site [ion binding]; other site
1002804000624	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1002804000625	prephenate dehydrogenase; Validated; Region: PRK08507
1002804000626	Prephenate dehydrogenase; Region: PDH; pfam02153
1002804000627	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1002804000628	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000629	Walker A motif; other site
1002804000630	ATP binding site [chemical binding]; other site
1002804000631	Walker B motif; other site
1002804000632	arginine finger; other site
1002804000633	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1002804000634	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1002804000635	flagellar assembly protein FliW; Provisional; Region: PRK13282
1002804000636	potential frameshift: common BLAST hit: gi|315453518|ref|YP_004073788.1| pyrroline-5-carboxylate reductase
1002804000637	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1002804000638	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1002804000639	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1002804000640	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1002804000641	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1002804000642	thiamine phosphate binding site [chemical binding]; other site
1002804000643	pyrophosphate binding site [ion binding]; other site
1002804000644	active site
1002804000645	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1002804000646	L-lactate transport; Region: lctP; TIGR00795
1002804000647	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1002804000648	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1002804000649	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1002804000650	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1002804000651	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1002804000652	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1002804000653	G1 box; other site
1002804000654	GTP/Mg2+ binding site [chemical binding]; other site
1002804000655	G2 box; other site
1002804000656	Switch I region; other site
1002804000657	G3 box; other site
1002804000658	Switch II region; other site
1002804000659	G4 box; other site
1002804000660	G5 box; other site
1002804000661	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1002804000662	Domain III of Elongation factor (EF) Tu (EF-TU) and EF-G.  Elongation factors (EF) EF-Tu and EF-G participate in the elongation phase during protein biosynthesis on the ribosome. Their functional cycles depend on GTP binding and its hydrolysis. The EF-Tu...; Region: Translation_factor_III; cl02786
1002804000663	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1002804000664	Restriction endonuclease BglII; Region: Endonuc-BglII; pfam09195
1002804000665	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804000666	DNA methylase; Region: N6_N4_Mtase; pfam01555
1002804000667	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1002804000668	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1002804000669	Walker A motif; other site
1002804000670	ATP binding site [chemical binding]; other site
1002804000671	Walker B motif; other site
1002804000672	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1002804000673	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1002804000674	metal ion-dependent adhesion site (MIDAS); other site
1002804000675	MraW methylase family; Region: Methyltransf_5; cl17771
1002804000676	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1002804000677	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1002804000678	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1002804000679	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
1002804000680	active site
1002804000681	Zn binding site [ion binding]; other site
1002804000682	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
1002804000683	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1002804000684	minor groove reading motif; other site
1002804000685	helix-hairpin-helix signature motif; other site
1002804000686	active site
1002804000687	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1002804000688	substrate binding site [chemical binding]; other site
1002804000689	active site
1002804000690	potential frameshift: common BLAST hit: gi|315452793|ref|YP_004073063.1| putative inner membrane protein
1002804000691	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1002804000692	Domain of unknown function DUF59; Region: DUF59; cl00941
1002804000693	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1002804000694	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1002804000695	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1002804000696	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1002804000697	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
1002804000698	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1002804000699	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1002804000700	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1002804000701	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1002804000702	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1002804000703	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1002804000704	GTP cyclohydrolase I; Provisional; Region: PLN03044
1002804000705	active site
1002804000706	heat shock protein HtpX; Provisional; Region: PRK02870
1002804000707	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1002804000708	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1002804000709	Permutation of conserved domain; other site
1002804000710	active site
1002804000711	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1002804000712	potential frameshift: common BLAST hit: gi|315453651|ref|YP_004073921.1| putative glycerol kinase
1002804000713	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1002804000714	N- and C-terminal domain interface [polypeptide binding]; other site
1002804000715	active site
1002804000716	MgATP binding site [chemical binding]; other site
1002804000717	catalytic site [active]
1002804000718	metal binding site [ion binding]; metal-binding site
1002804000719	glycerol binding site [chemical binding]; other site
1002804000720	homotetramer interface [polypeptide binding]; other site
1002804000721	homodimer interface [polypeptide binding]; other site
1002804000722	FBP binding site [chemical binding]; other site
1002804000723	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1002804000724	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1002804000725	amphipathic channel; other site
1002804000726	Asn-Pro-Ala signature motifs; other site
1002804000727	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1002804000728	Clp amino terminal domain; Region: Clp_N; pfam02861
1002804000729	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000730	Walker A motif; other site
1002804000731	ATP binding site [chemical binding]; other site
1002804000732	Walker B motif; other site
1002804000733	arginine finger; other site
1002804000734	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000735	Walker A motif; other site
1002804000736	ATP binding site [chemical binding]; other site
1002804000737	Walker B motif; other site
1002804000738	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1002804000739	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
1002804000740	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804000741	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000742	dimer interface [polypeptide binding]; other site
1002804000743	putative CheW interface [polypeptide binding]; other site
1002804000744	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
1002804000745	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804000746	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000747	dimer interface [polypeptide binding]; other site
1002804000748	putative CheW interface [polypeptide binding]; other site
1002804000749	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1002804000750	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1002804000751	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1002804000752	active site
1002804000753	substrate binding site [chemical binding]; other site
1002804000754	metal binding site [ion binding]; metal-binding site
1002804000755	Response regulator receiver domain; Region: Response_reg; pfam00072
1002804000756	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804000757	active site
1002804000758	dimerization interface [polypeptide binding]; other site
1002804000759	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
1002804000760	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1002804000761	substrate binding site; other site
1002804000762	dimer interface; other site
1002804000763	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1002804000764	homotrimer interaction site [polypeptide binding]; other site
1002804000765	zinc binding site [ion binding]; other site
1002804000766	CDP-binding sites; other site
1002804000767	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
1002804000768	ThiC family; Region: ThiC; pfam01964
1002804000769	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1002804000770	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
1002804000771	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1002804000772	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1002804000773	homodimer interface [polypeptide binding]; other site
1002804000774	NADP binding site [chemical binding]; other site
1002804000775	substrate binding site [chemical binding]; other site
1002804000776	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1002804000777	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1002804000778	Catalytic site [active]
1002804000779	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1002804000780	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1002804000781	Regulator of replication initiation timing [Replication,    recombination, and repair]; Region: COG4467; cl01853
1002804000782	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1002804000783	active site
1002804000784	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1002804000785	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1002804000786	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1002804000787	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1002804000788	interface (dimer of trimers) [polypeptide binding]; other site
1002804000789	Substrate-binding/catalytic site; other site
1002804000790	Zn-binding sites [ion binding]; other site
1002804000791	GTP-binding protein YchF; Reviewed; Region: PRK09601
1002804000792	YchF GTPase; Region: YchF; cd01900
1002804000793	G1 box; other site
1002804000794	GTP/Mg2+ binding site [chemical binding]; other site
1002804000795	Switch I region; other site
1002804000796	G2 box; other site
1002804000797	Switch II region; other site
1002804000798	G3 box; other site
1002804000799	G4 box; other site
1002804000800	G5 box; other site
1002804000801	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1002804000802	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1002804000803	Response regulator receiver domain; Region: Response_reg; pfam00072
1002804000804	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804000805	active site
1002804000806	phosphorylation site [posttranslational modification]
1002804000807	intermolecular recognition site; other site
1002804000808	dimerization interface [polypeptide binding]; other site
1002804000809	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
1002804000810	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
1002804000811	dimer interface [polypeptide binding]; other site
1002804000812	active site
1002804000813	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1002804000814	catalytic residues [active]
1002804000815	substrate binding site [chemical binding]; other site
1002804000816	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1002804000817	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1002804000818	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1002804000819	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1002804000820	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1002804000821	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1002804000822	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1002804000823	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1002804000824	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
1002804000825	nucleotide binding site/active site [active]
1002804000826	HIT family signature motif; other site
1002804000827	catalytic residue [active]
1002804000828	potential frameshift: common BLAST hit: gi|315453898|ref|YP_004074168.1| ribose-phosphate pyrophosphokinase
1002804000829	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1002804000830	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1002804000831	active site
1002804000832	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1002804000833	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1002804000834	GDP-binding site [chemical binding]; other site
1002804000835	ACT binding site; other site
1002804000836	IMP binding site; other site
1002804000837	Rio2, N-terminal; Region: Rio2_N; pfam09202
1002804000838	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1002804000839	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
1002804000840	NapD protein; Region: NapD; cl01163
1002804000841	ferredoxin-type protein; Provisional; Region: PRK10194
1002804000842	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1002804000843	active site
1002804000844	putative catalytic site [active]
1002804000845	DNA binding site [nucleotide binding]
1002804000846	putative phosphate binding site [ion binding]; other site
1002804000847	metal binding site A [ion binding]; metal-binding site
1002804000848	AP binding site [nucleotide binding]; other site
1002804000849	metal binding site B [ion binding]; metal-binding site
1002804000850	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1002804000851	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1002804000852	Protein of unknown function (DUF354); Region: DUF354; pfam04007
1002804000853	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1002804000854	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
1002804000855	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804000856	FeS/SAM binding site; other site
1002804000857	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1002804000858	putative acyl-acceptor binding pocket; other site
1002804000859	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1002804000860	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1002804000861	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1002804000862	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
1002804000863	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804000864	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1002804000865	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1002804000866	ring oligomerisation interface [polypeptide binding]; other site
1002804000867	ATP/Mg binding site [chemical binding]; other site
1002804000868	stacking interactions; other site
1002804000869	hinge regions; other site
1002804000870	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1002804000871	oligomerisation interface [polypeptide binding]; other site
1002804000872	mobile loop; other site
1002804000873	roof hairpin; other site
1002804000874	DNA primase, catalytic core; Region: dnaG; TIGR01391
1002804000875	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1002804000876	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1002804000877	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1002804000878	active site
1002804000879	metal binding site [ion binding]; metal-binding site
1002804000880	interdomain interaction site; other site
1002804000881	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1002804000882	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1002804000883	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1002804000884	Ligand Binding Site [chemical binding]; other site
1002804000885	VirB8 protein; Region: VirB8; cl01500
1002804000886	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1002804000887	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1002804000888	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1002804000889	substrate binding site [chemical binding]; other site
1002804000890	hexamer interface [polypeptide binding]; other site
1002804000891	metal binding site [ion binding]; metal-binding site
1002804000892	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1002804000893	active site
1002804000894	catalytic site [active]
1002804000895	substrate binding site [chemical binding]; other site
1002804000896	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
1002804000897	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804000898	Response regulator receiver domain; Region: Response_reg; pfam00072
1002804000899	active site
1002804000900	phosphorylation site [posttranslational modification]
1002804000901	intermolecular recognition site; other site
1002804000902	dimerization interface [polypeptide binding]; other site
1002804000903	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1002804000904	putative binding surface; other site
1002804000905	active site
1002804000906	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1002804000907	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1002804000908	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1002804000909	ATP binding site [chemical binding]; other site
1002804000910	Mg2+ binding site [ion binding]; other site
1002804000911	G-X-G motif; other site
1002804000912	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1002804000913	Response regulator receiver domain; Region: Response_reg; pfam00072
1002804000914	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804000915	active site
1002804000916	phosphorylation site [posttranslational modification]
1002804000917	intermolecular recognition site; other site
1002804000918	dimerization interface [polypeptide binding]; other site
1002804000919	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1002804000920	putative CheA interaction surface; other site
1002804000921	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804000922	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000923	putative CheW interface [polypeptide binding]; other site
1002804000924	Transglycosylase; Region: Transgly; pfam00912
1002804000925	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1002804000926	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1002804000927	Cache domain; Region: Cache_1; pfam02743
1002804000928	HAMP domain; Region: HAMP; pfam00672
1002804000929	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1002804000930	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000931	dimer interface [polypeptide binding]; other site
1002804000932	putative CheW interface [polypeptide binding]; other site
1002804000933	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
1002804000934	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1002804000935	Walker A/P-loop; other site
1002804000936	ATP binding site [chemical binding]; other site
1002804000937	Q-loop/lid; other site
1002804000938	ABC transporter signature motif; other site
1002804000939	Walker B; other site
1002804000940	D-loop; other site
1002804000941	H-loop/switch region; other site
1002804000942	crystallin beta/gamma motif-containing protein; Region: PHA00657
1002804000943	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1002804000944	metal binding triad [ion binding]; metal-binding site
1002804000945	potential frameshift: common BLAST hit: gi|315453940|ref|YP_004074210.1| excinuclease ABC subunit B
1002804000946	excinuclease ABC subunit B; Provisional; Region: PRK05298
1002804000947	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1002804000948	ATP binding site [chemical binding]; other site
1002804000949	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1002804000950	nucleotide binding region [chemical binding]; other site
1002804000951	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1002804000952	ATP-binding site [chemical binding]; other site
1002804000953	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1002804000954	UvrB/uvrC motif; Region: UVR; pfam02151
1002804000955	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1002804000956	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1002804000957	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1002804000958	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1002804000959	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1002804000960	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1002804000961	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1002804000962	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1002804000963	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1002804000964	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1002804000965	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1002804000966	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804000967	FeS/SAM binding site; other site
1002804000968	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1002804000969	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804000970	Walker B motif; other site
1002804000971	arginine finger; other site
1002804000972	Peptidase family M41; Region: Peptidase_M41; pfam01434
1002804000973	potential frameshift: common BLAST hit: gi|315452980|ref|YP_004073250.1| methyl-accepting chemotaxis sensory transducer
1002804000974	Cache domain; Region: Cache_1; pfam02743
1002804000975	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1002804000976	dimerization interface [polypeptide binding]; other site
1002804000977	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1002804000978	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804000979	dimer interface [polypeptide binding]; other site
1002804000980	putative CheW interface [polypeptide binding]; other site
1002804000981	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1002804000982	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1002804000983	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1002804000984	DNA repair protein RadA; Provisional; Region: PRK11823
1002804000985	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1002804000986	Walker A motif; other site
1002804000987	ATP binding site [chemical binding]; other site
1002804000988	Walker B motif; other site
1002804000989	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1002804000990	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1002804000991	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1002804000992	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1002804000993	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1002804000994	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804000995	dimer interface [polypeptide binding]; other site
1002804000996	conserved gate region; other site
1002804000997	putative PBP binding loops; other site
1002804000998	ABC-ATPase subunit interface; other site
1002804000999	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1002804001000	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1002804001001	putative PBP binding loops; other site
1002804001002	dimer interface [polypeptide binding]; other site
1002804001003	ABC-ATPase subunit interface; other site
1002804001004	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804001005	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1002804001006	Walker A/P-loop; other site
1002804001007	ATP binding site [chemical binding]; other site
1002804001008	Q-loop/lid; other site
1002804001009	ABC transporter signature motif; other site
1002804001010	Walker B; other site
1002804001011	D-loop; other site
1002804001012	H-loop/switch region; other site
1002804001013	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1002804001014	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1002804001015	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1002804001016	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1002804001017	elongation factor Ts; Reviewed; Region: tsf; PRK12332
1002804001018	UBA/TS-N domain; Region: UBA; pfam00627
1002804001019	Elongation factor TS; Region: EF_TS; pfam00889
1002804001020	Elongation factor TS; Region: EF_TS; pfam00889
1002804001021	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1002804001022	rRNA interaction site [nucleotide binding]; other site
1002804001023	S8 interaction site; other site
1002804001024	putative laminin-1 binding site; other site
1002804001025	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
1002804001026	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
1002804001027	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1002804001028	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1002804001029	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1002804001030	active site
1002804001031	Cupin domain; Region: Cupin_2; cl17218
1002804001032	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1002804001033	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1002804001034	NADP-binding site; other site
1002804001035	homotetramer interface [polypeptide binding]; other site
1002804001036	substrate binding site [chemical binding]; other site
1002804001037	homodimer interface [polypeptide binding]; other site
1002804001038	active site
1002804001039	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1002804001040	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1002804001041	Predicted permease [General function prediction only]; Region: COG2056
1002804001042	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1002804001043	potential frameshift: common BLAST hit: gi|315453234|ref|YP_004073504.1| putative carbon-nitrogen hydrolase
1002804001044	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1002804001045	putative active site; other site
1002804001046	catalytic triad [active]
1002804001047	putative dimer interface [polypeptide binding]; other site
1002804001048	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1002804001049	Nitrate reductase cytochrome c-type subunit (NapB); Region: NapB; pfam03892
1002804001050	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804001051	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1002804001052	FeS/SAM binding site; other site
1002804001053	DNA topoisomerase I; Validated; Region: PRK05582
1002804001054	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1002804001055	active site
1002804001056	interdomain interaction site; other site
1002804001057	putative metal-binding site [ion binding]; other site
1002804001058	nucleotide binding site [chemical binding]; other site
1002804001059	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1002804001060	domain I; other site
1002804001061	DNA binding groove [nucleotide binding]
1002804001062	phosphate binding site [ion binding]; other site
1002804001063	domain II; other site
1002804001064	domain III; other site
1002804001065	nucleotide binding site [chemical binding]; other site
1002804001066	catalytic site [active]
1002804001067	domain IV; other site
1002804001068	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1002804001069	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1002804001070	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1002804001071	flagellin B; Provisional; Region: PRK13588
1002804001072	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1002804001073	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1002804001074	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1002804001075	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1002804001076	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1002804001077	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804001078	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804001079	catalytic residue [active]
1002804001080	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804001081	Nitrate and nitrite sensing; Region: NIT; pfam08376
1002804001082	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804001083	HAMP domain; Region: HAMP; pfam00672
1002804001084	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804001085	dimer interface [polypeptide binding]; other site
1002804001086	putative CheW interface [polypeptide binding]; other site
1002804001087	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1002804001088	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1002804001089	active site
1002804001090	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1002804001091	protein binding site [polypeptide binding]; other site
1002804001092	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1002804001093	putative substrate binding region [chemical binding]; other site
1002804001094	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1002804001095	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
1002804001096	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
1002804001097	putative NAD(P) binding site [chemical binding]; other site
1002804001098	active site
1002804001099	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1002804001100	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1002804001101	dimer interface [polypeptide binding]; other site
1002804001102	active site
1002804001103	catalytic residue [active]
1002804001104	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1002804001105	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1002804001106	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1002804001107	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1002804001108	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1002804001109	quinone interaction residues [chemical binding]; other site
1002804001110	active site
1002804001111	catalytic residues [active]
1002804001112	FMN binding site [chemical binding]; other site
1002804001113	substrate binding site [chemical binding]; other site
1002804001114	polyphosphate kinase; Provisional; Region: PRK05443
1002804001115	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1002804001116	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1002804001117	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1002804001118	putative active site [active]
1002804001119	catalytic site [active]
1002804001120	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1002804001121	putative domain interface [polypeptide binding]; other site
1002804001122	putative active site [active]
1002804001123	catalytic site [active]
1002804001124	Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636
1002804001125	uncharacterized proteins similar to the Aspergillus nidulans lactam utilization protein LamB; Region: LamB_YcsF_like_2; cd11664
1002804001126	putative active site [active]
1002804001127	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1002804001128	carboxyltransferase (CT) interaction site; other site
1002804001129	biotinylation site [posttranslational modification]; other site
1002804001130	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1002804001131	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1002804001132	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1002804001133	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1002804001134	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
1002804001135	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1002804001136	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1002804001137	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1002804001138	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1002804001139	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1002804001140	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1002804001141	active site pocket [active]
1002804001142	oxyanion hole [active]
1002804001143	catalytic triad [active]
1002804001144	active site nucleophile [active]
1002804001145	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1002804001146	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1002804001147	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1002804001148	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1002804001149	putative recombination protein RecB; Provisional; Region: PRK13909
1002804001150	Family description; Region: UvrD_C_2; pfam13538
1002804001151	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
1002804001152	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1002804001153	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1002804001154	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1002804001155	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1002804001156	Protein export membrane protein; Region: SecD_SecF; pfam02355
1002804001157	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1002804001158	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1002804001159	HIGH motif; other site
1002804001160	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1002804001161	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1002804001162	active site
1002804001163	KMSKS motif; other site
1002804001164	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1002804001165	tRNA binding surface [nucleotide binding]; other site
1002804001166	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1002804001167	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
1002804001168	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1002804001169	Peptidase family M23; Region: Peptidase_M23; pfam01551
1002804001170	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1002804001171	Peptidase family M23; Region: Peptidase_M23; pfam01551
1002804001172	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1002804001173	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1002804001174	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1002804001175	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1002804001176	ATP binding site [chemical binding]; other site
1002804001177	putative Mg++ binding site [ion binding]; other site
1002804001178	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1002804001179	nucleotide binding region [chemical binding]; other site
1002804001180	ATP-binding site [chemical binding]; other site
1002804001181	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1002804001182	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804001183	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1002804001184	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1002804001185	minor groove reading motif; other site
1002804001186	helix-hairpin-helix signature motif; other site
1002804001187	substrate binding pocket [chemical binding]; other site
1002804001188	active site
1002804001189	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1002804001190	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1002804001191	DNA binding and oxoG recognition site [nucleotide binding]
1002804001192	potential frameshift: common BLAST hit: gi|315452598|ref|YP_004072868.1| Beta-1,4-galactosyltransferase
1002804001193	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1002804001194	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1002804001195	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
1002804001196	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1002804001197	inhibitor-cofactor binding pocket; inhibition site
1002804001198	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804001199	catalytic residue [active]
1002804001200	Isochorismatase family; Region: Isochorismatase; pfam00857
1002804001201	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1002804001202	catalytic triad [active]
1002804001203	dimer interface [polypeptide binding]; other site
1002804001204	conserved cis-peptide bond; other site
1002804001205	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1002804001206	potential frameshift: common BLAST hit: gi|315453053|ref|YP_004073323.1| phosphoribosylformylglycinamidine
1002804001207	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1002804001208	dimerization interface [polypeptide binding]; other site
1002804001209	ATP binding site [chemical binding]; other site
1002804001210	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1002804001211	conserved cys residue [active]
1002804001212	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1002804001213	dimerization interface [polypeptide binding]; other site
1002804001214	ATP binding site [chemical binding]; other site
1002804001215	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1002804001216	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1002804001217	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1002804001218	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1002804001219	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1002804001220	AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]; Region: PurH; COG0138
1002804001221	IMP cyclohydrolase-like protein; Region: IMP_cyclohyd; cl01330
1002804001222	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1002804001223	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1002804001224	dimerization interface [polypeptide binding]; other site
1002804001225	putative ATP binding site [chemical binding]; other site
1002804001226	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
1002804001227	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1002804001228	active site
1002804001229	tetramer interface [polypeptide binding]; other site
1002804001230	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1002804001231	active site
1002804001232	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1002804001233	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1002804001234	ATP binding site [chemical binding]; other site
1002804001235	active site
1002804001236	substrate binding site [chemical binding]; other site
1002804001237	AIR carboxylase; Region: AIRC; pfam00731
1002804001238	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001239	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001240	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001241	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001242	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001243	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001244	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804001245	potential frameshift: common BLAST hit: gi|315452940|ref|YP_004073210.1| bifunctional DNA-directed RNA polymerase beta' chain
1002804001246	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1002804001247	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1002804001248	DNA binding site [nucleotide binding]
1002804001249	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1002804001250	potential frameshift: common BLAST hit: gi|315452940|ref|YP_004073210.1| bifunctional DNA-directed RNA polymerase beta' chain
1002804001251	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1002804001252	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1002804001253	RPB3 interaction site [polypeptide binding]; other site
1002804001254	RPB1 interaction site [polypeptide binding]; other site
1002804001255	RPB11 interaction site [polypeptide binding]; other site
1002804001256	RPB10 interaction site [polypeptide binding]; other site
1002804001257	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1002804001258	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1002804001259	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1002804001260	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1002804001261	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1002804001262	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1002804001263	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1002804001264	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1002804001265	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1002804001266	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1002804001267	RPB11 interaction site [polypeptide binding]; other site
1002804001268	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1002804001269	core dimer interface [polypeptide binding]; other site
1002804001270	peripheral dimer interface [polypeptide binding]; other site
1002804001271	L10 interface [polypeptide binding]; other site
1002804001272	L11 interface [polypeptide binding]; other site
1002804001273	putative EF-Tu interaction site [polypeptide binding]; other site
1002804001274	putative EF-G interaction site [polypeptide binding]; other site
1002804001275	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1002804001276	23S rRNA interface [nucleotide binding]; other site
1002804001277	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1002804001278	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1002804001279	mRNA/rRNA interface [nucleotide binding]; other site
1002804001280	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1002804001281	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1002804001282	23S rRNA interface [nucleotide binding]; other site
1002804001283	L7/L12 interface [polypeptide binding]; other site
1002804001284	putative thiostrepton binding site; other site
1002804001285	L25 interface [polypeptide binding]; other site
1002804001286	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1002804001287	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1002804001288	putative homodimer interface [polypeptide binding]; other site
1002804001289	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1002804001290	heterodimer interface [polypeptide binding]; other site
1002804001291	homodimer interface [polypeptide binding]; other site
1002804001292	tRNA-specific 2-thiouridylase MnmA; Reviewed; Region: mnmA; PRK00143
1002804001293	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1002804001294	elongation factor Tu; Reviewed; Region: PRK00049
1002804001295	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1002804001296	G1 box; other site
1002804001297	GEF interaction site [polypeptide binding]; other site
1002804001298	GTP/Mg2+ binding site [chemical binding]; other site
1002804001299	Switch I region; other site
1002804001300	G2 box; other site
1002804001301	G3 box; other site
1002804001302	Switch II region; other site
1002804001303	G4 box; other site
1002804001304	G5 box; other site
1002804001305	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1002804001306	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1002804001307	Antibiotic Binding Site [chemical binding]; other site
1002804001308	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
1002804001309	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1002804001310	DNA binding residues [nucleotide binding]
1002804001311	putative dimer interface [polypeptide binding]; other site
1002804001312	chaperone protein DnaJ; Provisional; Region: PRK14299
1002804001313	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1002804001314	HSP70 interaction site [polypeptide binding]; other site
1002804001315	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1002804001316	substrate binding site [polypeptide binding]; other site
1002804001317	dimer interface [polypeptide binding]; other site
1002804001318	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1002804001319	Ligand Binding Site [chemical binding]; other site
1002804001320	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1002804001321	active site
1002804001322	NTP binding site [chemical binding]; other site
1002804001323	metal binding triad [ion binding]; metal-binding site
1002804001324	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1002804001325	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1002804001326	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1002804001327	FMN binding site [chemical binding]; other site
1002804001328	active site
1002804001329	catalytic residues [active]
1002804001330	substrate binding site [chemical binding]; other site
1002804001331	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
1002804001332	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1002804001333	active site
1002804001334	HIGH motif; other site
1002804001335	nucleotide binding site [chemical binding]; other site
1002804001336	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1002804001337	active site
1002804001338	KMSKS motif; other site
1002804001339	YGGT family; Region: YGGT; pfam02325
1002804001340	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1002804001341	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1002804001342	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1002804001343	catalytic residue [active]
1002804001344	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1002804001345	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1002804001346	active site
1002804001347	tetramer interface; other site
1002804001348	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1002804001349	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1002804001350	hinge; other site
1002804001351	active site
1002804001352	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1002804001353	active site
1002804001354	homotetramer interface [polypeptide binding]; other site
1002804001355	homodimer interface [polypeptide binding]; other site
1002804001356	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
1002804001357	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1002804001358	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1002804001359	Walker A/P-loop; other site
1002804001360	ATP binding site [chemical binding]; other site
1002804001361	Q-loop/lid; other site
1002804001362	ABC transporter signature motif; other site
1002804001363	Walker B; other site
1002804001364	D-loop; other site
1002804001365	H-loop/switch region; other site
1002804001366	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1002804001367	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1002804001368	Walker A/P-loop; other site
1002804001369	ATP binding site [chemical binding]; other site
1002804001370	Q-loop/lid; other site
1002804001371	ABC transporter signature motif; other site
1002804001372	Walker B; other site
1002804001373	D-loop; other site
1002804001374	H-loop/switch region; other site
1002804001375	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1002804001376	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
1002804001377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804001378	putative PBP binding loops; other site
1002804001379	dimer interface [polypeptide binding]; other site
1002804001380	ABC-ATPase subunit interface; other site
1002804001381	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1002804001382	trimer interface [polypeptide binding]; other site
1002804001383	active site
1002804001384	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1002804001385	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1002804001386	Ligand Binding Site [chemical binding]; other site
1002804001387	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
1002804001388	Clp amino terminal domain; Region: Clp_N; pfam02861
1002804001389	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804001390	Walker A motif; other site
1002804001391	ATP binding site [chemical binding]; other site
1002804001392	Walker B motif; other site
1002804001393	arginine finger; other site
1002804001394	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804001395	Walker A motif; other site
1002804001396	ATP binding site [chemical binding]; other site
1002804001397	Walker B motif; other site
1002804001398	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1002804001399	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1002804001400	tetramerization interface [polypeptide binding]; other site
1002804001401	active site
1002804001402	hypothetical protein; Provisional; Region: PRK03762
1002804001403	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1002804001404	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1002804001405	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1002804001406	substrate binding pocket [chemical binding]; other site
1002804001407	chain length determination region; other site
1002804001408	substrate-Mg2+ binding site; other site
1002804001409	catalytic residues [active]
1002804001410	aspartate-rich region 1; other site
1002804001411	active site lid residues [active]
1002804001412	aspartate-rich region 2; other site
1002804001413	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1002804001414	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1002804001415	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1002804001416	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1002804001417	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1002804001418	DHH family; Region: DHH; pfam01368
1002804001419	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1002804001420	NAD synthetase; Provisional; Region: PRK13980
1002804001421	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1002804001422	homodimer interface [polypeptide binding]; other site
1002804001423	NAD binding pocket [chemical binding]; other site
1002804001424	ATP binding pocket [chemical binding]; other site
1002804001425	Mg binding site [ion binding]; other site
1002804001426	active-site loop [active]
1002804001427	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
1002804001428	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1002804001429	iron-sulfur cluster [ion binding]; other site
1002804001430	[2Fe-2S] cluster binding site [ion binding]; other site
1002804001431	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1002804001432	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1002804001433	intrachain domain interface; other site
1002804001434	interchain domain interface [polypeptide binding]; other site
1002804001435	heme bH binding site [chemical binding]; other site
1002804001436	Qi binding site; other site
1002804001437	heme bL binding site [chemical binding]; other site
1002804001438	Qo binding site; other site
1002804001439	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
1002804001440	interchain domain interface [polypeptide binding]; other site
1002804001441	intrachain domain interface; other site
1002804001442	Qi binding site; other site
1002804001443	Qo binding site; other site
1002804001444	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
1002804001445	Cytochrome c; Region: Cytochrom_C; pfam00034
1002804001446	Cytochrome c; Region: Cytochrom_C; cl11414
1002804001447	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1002804001448	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1002804001449	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804001450	catalytic residue [active]
1002804001451	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1002804001452	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1002804001453	Sulfatase; Region: Sulfatase; cl17466
1002804001454	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1002804001455	Sulfatase; Region: Sulfatase; cl17466
1002804001456	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1002804001457	Sulfatase; Region: Sulfatase; pfam00884
1002804001458	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
1002804001459	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1002804001460	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1002804001461	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1002804001462	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1002804001463	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1002804001464	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1002804001465	Switch I; other site
1002804001466	Switch II; other site
1002804001467	Septum formation topological specificity factor MinE; Region: MinE; cl00538
1002804001468	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1002804001469	DNA protecting protein DprA; Region: dprA; TIGR00732
1002804001470	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1002804001471	hypothetical protein; Provisional; Region: PRK12378
1002804001472	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1002804001473	dimer interface [polypeptide binding]; other site
1002804001474	active site
1002804001475	Schiff base residues; other site
1002804001476	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1002804001477	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1002804001478	active site
1002804001479	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
1002804001480	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1002804001481	Sulfatase; Region: Sulfatase; pfam00884
1002804001482	type II citrate synthase; Reviewed; Region: gltA; PRK05614
1002804001483	Citrate synthase; Region: Citrate_synt; pfam00285
1002804001484	oxalacetate binding site [chemical binding]; other site
1002804001485	citrylCoA binding site [chemical binding]; other site
1002804001486	coenzyme A binding site [chemical binding]; other site
1002804001487	catalytic triad [active]
1002804001488	potential frameshift: common BLAST hit: gi|315453032|ref|YP_004073302.1| putative 3-isopropylmalate dehydrogenase/isocitrate dehydrogenase
1002804001489	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1002804001490	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1002804001491	Pirin-related protein [General function prediction only]; Region: COG1741
1002804001492	Pirin; Region: Pirin; pfam02678
1002804001493	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1002804001494	flagellar motor switch protein FliY; Validated; Region: PRK08432
1002804001495	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1002804001496	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1002804001497	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1002804001498	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1002804001499	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1002804001500	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1002804001501	DNA binding residues [nucleotide binding]
1002804001502	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1002804001503	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1002804001504	P-loop; other site
1002804001505	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1002804001506	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
1002804001507	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1002804001508	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
1002804001509	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1002804001510	catalytic center binding site [active]
1002804001511	ATP binding site [chemical binding]; other site
1002804001512	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1002804001513	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1002804001514	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1002804001515	active site
1002804001516	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1002804001517	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1002804001518	trimer interface [polypeptide binding]; other site
1002804001519	active site
1002804001520	dimer interface [polypeptide binding]; other site
1002804001521	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1002804001522	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1002804001523	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804001524	dimer interface [polypeptide binding]; other site
1002804001525	putative CheW interface [polypeptide binding]; other site
1002804001526	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
1002804001527	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1002804001528	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1002804001529	active site
1002804001530	HIGH motif; other site
1002804001531	nucleotide binding site [chemical binding]; other site
1002804001532	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1002804001533	active site
1002804001534	KMSKS motif; other site
1002804001535	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1002804001536	tRNA binding surface [nucleotide binding]; other site
1002804001537	anticodon binding site; other site
1002804001538	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1002804001539	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
1002804001540	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1002804001541	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1002804001542	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1002804001543	TrkA-N domain; Region: TrkA_N; pfam02254
1002804001544	TrkA-C domain; Region: TrkA_C; pfam02080
1002804001545	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1002804001546	4Fe-4S dicluster domain; Region: Fer4_18; pfam13746
1002804001547	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1002804001548	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
1002804001549	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804001550	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1002804001551	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1002804001552	Cysteine-rich domain; Region: CCG; pfam02754
1002804001553	Cysteine-rich domain; Region: CCG; pfam02754
1002804001554	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1002804001555	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804001556	FeS/SAM binding site; other site
1002804001557	HemN C-terminal domain; Region: HemN_C; pfam06969
1002804001558	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
1002804001559	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1002804001560	Chorismate synthase; Region: Chorismate_synt; pfam01264
1002804001561	Tetramer interface [polypeptide binding]; other site
1002804001562	active site
1002804001563	FMN-binding site [chemical binding]; other site
1002804001564	ribonuclease III; Reviewed; Region: rnc; PRK00102
1002804001565	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1002804001566	dimerization interface [polypeptide binding]; other site
1002804001567	active site
1002804001568	metal binding site [ion binding]; metal-binding site
1002804001569	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1002804001570	dsRNA binding site [nucleotide binding]; other site
1002804001571	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1002804001572	RNA/DNA hybrid binding site [nucleotide binding]; other site
1002804001573	active site
1002804001574	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804001575	binding surface
1002804001576	TPR motif; other site
1002804001577	Bacterial transcriptional activator domain; Region: BTAD; smart01043
1002804001578	SurA N-terminal domain; Region: SurA_N; pfam09312
1002804001579	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1002804001580	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
1002804001581	NAD binding site [chemical binding]; other site
1002804001582	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1002804001583	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1002804001584	putative active site [active]
1002804001585	heme pocket [chemical binding]; other site
1002804001586	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1002804001587	putative active site [active]
1002804001588	heme pocket [chemical binding]; other site
1002804001589	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804001590	dimer interface [polypeptide binding]; other site
1002804001591	putative CheW interface [polypeptide binding]; other site
1002804001592	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1002804001593	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1002804001594	substrate binding pocket [chemical binding]; other site
1002804001595	membrane-bound complex binding site; other site
1002804001596	hinge residues; other site
1002804001597	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1002804001598	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1002804001599	Walker A/P-loop; other site
1002804001600	ATP binding site [chemical binding]; other site
1002804001601	Q-loop/lid; other site
1002804001602	ABC transporter signature motif; other site
1002804001603	Walker B; other site
1002804001604	D-loop; other site
1002804001605	H-loop/switch region; other site
1002804001606	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804001607	dimer interface [polypeptide binding]; other site
1002804001608	conserved gate region; other site
1002804001609	putative PBP binding loops; other site
1002804001610	ABC-ATPase subunit interface; other site
1002804001611	potential frameshift: common BLAST hit: gi|315452694|ref|YP_004072964.1| amino-acid ABC transporter integral membrane protein
1002804001612	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804001613	ABC-ATPase subunit interface; other site
1002804001614	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1002804001615	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1002804001616	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1002804001617	substrate binding site [chemical binding]; other site
1002804001618	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1002804001619	substrate binding site [chemical binding]; other site
1002804001620	ligand binding site [chemical binding]; other site
1002804001621	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
1002804001622	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1002804001623	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1002804001624	active site
1002804001625	metal binding site [ion binding]; metal-binding site
1002804001626	Nitronate monooxygenase; Region: NMO; pfam03060
1002804001627	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1002804001628	FMN binding site [chemical binding]; other site
1002804001629	substrate binding site [chemical binding]; other site
1002804001630	putative catalytic residue [active]
1002804001631	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1002804001632	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1002804001633	active site
1002804001634	HIGH motif; other site
1002804001635	dimer interface [polypeptide binding]; other site
1002804001636	KMSKS motif; other site
1002804001637	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1002804001638	RNA binding surface [nucleotide binding]; other site
1002804001639	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
1002804001640	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1002804001641	Zn2+ binding site [ion binding]; other site
1002804001642	Mg2+ binding site [ion binding]; other site
1002804001643	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1002804001644	synthetase active site [active]
1002804001645	NTP binding site [chemical binding]; other site
1002804001646	metal binding site [ion binding]; metal-binding site
1002804001647	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1002804001648	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1002804001649	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1002804001650	putative nucleotide binding site [chemical binding]; other site
1002804001651	uridine monophosphate binding site [chemical binding]; other site
1002804001652	homohexameric interface [polypeptide binding]; other site
1002804001653	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
1002804001654	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1002804001655	inhibitor-cofactor binding pocket; inhibition site
1002804001656	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804001657	catalytic residue [active]
1002804001658	SurA N-terminal domain; Region: SurA_N_3; cl07813
1002804001659	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1002804001660	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1002804001661	cell division protein FtsA; Region: ftsA; TIGR01174
1002804001662	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1002804001663	nucleotide binding site [chemical binding]; other site
1002804001664	Cell division protein FtsA; Region: FtsA; pfam14450
1002804001665	cell division protein FtsZ; Validated; Region: PRK09330
1002804001666	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1002804001667	nucleotide binding site [chemical binding]; other site
1002804001668	SulA interaction site; other site
1002804001669	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1002804001670	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1002804001671	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
1002804001672	TrkA-C domain; Region: TrkA_C; pfam02080
1002804001673	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1002804001674	active site
1002804001675	dimer interface [polypeptide binding]; other site
1002804001676	metal binding site [ion binding]; metal-binding site
1002804001677	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1002804001678	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1002804001679	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1002804001680	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1002804001681	Walker A motif; other site
1002804001682	hexamer interface [polypeptide binding]; other site
1002804001683	ATP binding site [chemical binding]; other site
1002804001684	Walker B motif; other site
1002804001685	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1002804001686	active site
1002804001687	potential frameshift: common BLAST hit: gi|315453708|ref|YP_004073978.1| outer membrane protein
1002804001688	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001689	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001690	potential frameshift: common BLAST hit: gi|315452512|ref|YP_004072782.1| methyl-accepting chemotaxis protein TlpA
1002804001691	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804001692	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
1002804001693	Sm and related proteins; Region: Sm_like; cl00259
1002804001694	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1002804001695	putative oligomer interface [polypeptide binding]; other site
1002804001696	putative RNA binding site [nucleotide binding]; other site
1002804001697	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1002804001698	potential frameshift: common BLAST hit: gi|315452834|ref|YP_004073104.1| translation initiation factor IF-2
1002804001699	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
1002804001700	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1002804001701	G1 box; other site
1002804001702	putative GEF interaction site [polypeptide binding]; other site
1002804001703	GTP/Mg2+ binding site [chemical binding]; other site
1002804001704	Switch I region; other site
1002804001705	G2 box; other site
1002804001706	G3 box; other site
1002804001707	Switch II region; other site
1002804001708	G4 box; other site
1002804001709	G5 box; other site
1002804001710	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1002804001711	Translation-initiation factor 2; Region: IF-2; pfam11987
1002804001712	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1002804001713	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1002804001714	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1002804001715	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cl00189
1002804001716	homoserine kinase; Provisional; Region: PRK01212
1002804001717	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1002804001718	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1002804001719	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1002804001720	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1002804001721	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1002804001722	septum formation inhibitor; Reviewed; Region: minC; PRK00556
1002804001723	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1002804001724	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1002804001725	Peptidase family M23; Region: Peptidase_M23; pfam01551
1002804001726	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804001727	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804001728	Uncharacterized protein family (UPF0254); Region: UPF0254; cl01641
1002804001729	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1002804001730	active site
1002804001731	oligomerization interface [polypeptide binding]; other site
1002804001732	metal binding site [ion binding]; metal-binding site
1002804001733	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1002804001734	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804001735	Walker A motif; other site
1002804001736	ATP binding site [chemical binding]; other site
1002804001737	Walker B motif; other site
1002804001738	arginine finger; other site
1002804001739	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1002804001740	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1002804001741	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1002804001742	Mg2+ binding site [ion binding]; other site
1002804001743	G-X-G motif; other site
1002804001744	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1002804001745	anchoring element; other site
1002804001746	dimer interface [polypeptide binding]; other site
1002804001747	ATP binding site [chemical binding]; other site
1002804001748	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1002804001749	active site
1002804001750	putative metal-binding site [ion binding]; other site
1002804001751	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1002804001752	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1002804001753	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804001754	Walker A motif; other site
1002804001755	ATP binding site [chemical binding]; other site
1002804001756	Walker B motif; other site
1002804001757	arginine finger; other site
1002804001758	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1002804001759	DnaA box-binding interface [nucleotide binding]; other site
1002804001760	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1002804001761	active site
1002804001762	putative DNA-binding cleft [nucleotide binding]; other site
1002804001763	dimer interface [polypeptide binding]; other site
1002804001764	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
1002804001765	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804001766	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1002804001767	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804001768	dimer interface [polypeptide binding]; other site
1002804001769	putative CheW interface [polypeptide binding]; other site
1002804001770	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1002804001771	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1002804001772	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1002804001773	Heavy-metal-associated domain; Region: HMA; pfam00403
1002804001774	metal-binding site [ion binding]
1002804001775	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1002804001776	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1002804001777	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1002804001778	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1002804001779	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1002804001780	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1002804001781	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1002804001782	active site
1002804001783	catalytic residues [active]
1002804001784	metal binding site [ion binding]; metal-binding site
1002804001785	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1002804001786	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1002804001787	oligomer interface [polypeptide binding]; other site
1002804001788	active site residues [active]
1002804001789	trigger factor; Provisional; Region: tig; PRK01490
1002804001790	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1002804001791	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1002804001792	potential frameshift: common BLAST hit: gi|315453781|ref|YP_004074051.1| flagellum-specific ATP synthase
1002804001793	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
1002804001794	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1002804001795	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1002804001796	Walker A motif/ATP binding site; other site
1002804001797	Walker B motif; other site
1002804001798	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804001799	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1002804001800	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804001801	catalytic residue [active]
1002804001802	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1002804001803	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1002804001804	trimerization site [polypeptide binding]; other site
1002804001805	active site
1002804001806	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1002804001807	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1002804001808	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1002804001809	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1002804001810	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1002804001811	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
1002804001812	active site
1002804001813	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1002804001814	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1002804001815	putative catalytic motif [active]
1002804001816	substrate binding site [chemical binding]; other site
1002804001817	pyridoxine 5'-phosphate synthase; Provisional; Region: PRK05265
1002804001818	active site
1002804001819	hydrophilic channel; other site
1002804001820	dimerization interface [polypeptide binding]; other site
1002804001821	catalytic residues [active]
1002804001822	active site lid [active]
1002804001823	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1002804001824	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
1002804001825	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1002804001826	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1002804001827	RF-1 domain; Region: RF-1; pfam00472
1002804001828	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1002804001829	potential frameshift: common BLAST hit: gi|315453084|ref|YP_004073354.1| Phosphoglucosamine mutase
1002804001830	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
1002804001831	active site
1002804001832	substrate binding site [chemical binding]; other site
1002804001833	metal binding site [ion binding]; metal-binding site
1002804001834	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
1002804001835	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1002804001836	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804001837	Sel1-like repeats; Region: SEL1; smart00671
1002804001838	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1002804001839	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1002804001840	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1002804001841	TrkA-N domain; Region: TrkA_N; pfam02254
1002804001842	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1002804001843	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804001844	Walker A/P-loop; other site
1002804001845	ATP binding site [chemical binding]; other site
1002804001846	Q-loop/lid; other site
1002804001847	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804001848	Walker B; other site
1002804001849	D-loop; other site
1002804001850	H-loop/switch region; other site
1002804001851	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1002804001852	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1002804001853	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1002804001854	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001855	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001856	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001857	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001858	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001859	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001860	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001861	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1002804001862	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1002804001863	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1002804001864	dimer interface [polypeptide binding]; other site
1002804001865	putative functional site; other site
1002804001866	putative MPT binding site; other site
1002804001867	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1002804001868	thiamine phosphate binding site [chemical binding]; other site
1002804001869	active site
1002804001870	pyrophosphate binding site [ion binding]; other site
1002804001871	GMP synthase; Reviewed; Region: guaA; PRK00074
1002804001872	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1002804001873	AMP/PPi binding site [chemical binding]; other site
1002804001874	candidate oxyanion hole; other site
1002804001875	catalytic triad [active]
1002804001876	potential glutamine specificity residues [chemical binding]; other site
1002804001877	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1002804001878	ATP Binding subdomain [chemical binding]; other site
1002804001879	Ligand Binding sites [chemical binding]; other site
1002804001880	Dimerization subdomain; other site
1002804001881	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1002804001882	heat shock protein 90; Provisional; Region: PRK05218
1002804001883	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1002804001884	ATP binding site [chemical binding]; other site
1002804001885	Mg2+ binding site [ion binding]; other site
1002804001886	G-X-G motif; other site
1002804001887	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1002804001888	active site
1002804001889	substrate binding site [chemical binding]; other site
1002804001890	cosubstrate binding site; other site
1002804001891	catalytic site [active]
1002804001892	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1002804001893	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1002804001894	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804001895	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1002804001896	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1002804001897	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1002804001898	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1002804001899	histidyl-tRNA synthetase; Region: hisS; TIGR00442
1002804001900	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1002804001901	dimer interface [polypeptide binding]; other site
1002804001902	motif 1; other site
1002804001903	active site
1002804001904	motif 2; other site
1002804001905	motif 3; other site
1002804001906	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1002804001907	anticodon binding site; other site
1002804001908	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1002804001909	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1002804001910	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
1002804001911	Domain of unknown function (DUF386); Region: DUF386; cl01047
1002804001912	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1002804001913	glutamine synthetase, type I; Region: GlnA; TIGR00653
1002804001914	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1002804001915	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1002804001916	carbon starvation protein A; Provisional; Region: PRK15015
1002804001917	Carbon starvation protein CstA; Region: CstA; pfam02554
1002804001918	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1002804001919	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
1002804001920	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1002804001921	dimerization interface [polypeptide binding]; other site
1002804001922	active site
1002804001923	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804001924	dimer interface [polypeptide binding]; other site
1002804001925	putative CheW interface [polypeptide binding]; other site
1002804001926	Ubiquitin-like proteins; Region: UBQ; cl00155
1002804001927	charged pocket; other site
1002804001928	hydrophobic patch; other site
1002804001929	potential frameshift: common BLAST hit: gi|308182956|ref|YP_003927083.1| molybdopterin converting factor, subunit 2
1002804001930	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cl00399
1002804001931	MoaE homodimer interface [polypeptide binding]; other site
1002804001932	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cl00399
1002804001933	active site residues [active]
1002804001934	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1002804001935	MPT binding site; other site
1002804001936	trimer interface [polypeptide binding]; other site
1002804001937	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1002804001938	trimer interface [polypeptide binding]; other site
1002804001939	dimer interface [polypeptide binding]; other site
1002804001940	putative active site [active]
1002804001941	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1002804001942	Sulfatase; Region: Sulfatase; pfam00884
1002804001943	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
1002804001944	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1002804001945	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1002804001946	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1002804001947	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1002804001948	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1002804001949	peptide binding site [polypeptide binding]; other site
1002804001950	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1002804001951	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804001952	dimer interface [polypeptide binding]; other site
1002804001953	conserved gate region; other site
1002804001954	putative PBP binding loops; other site
1002804001955	ABC-ATPase subunit interface; other site
1002804001956	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1002804001957	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1002804001958	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804001959	dimer interface [polypeptide binding]; other site
1002804001960	conserved gate region; other site
1002804001961	putative PBP binding loops; other site
1002804001962	ABC-ATPase subunit interface; other site
1002804001963	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1002804001964	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1002804001965	Walker A/P-loop; other site
1002804001966	ATP binding site [chemical binding]; other site
1002804001967	Q-loop/lid; other site
1002804001968	ABC transporter signature motif; other site
1002804001969	Walker B; other site
1002804001970	D-loop; other site
1002804001971	H-loop/switch region; other site
1002804001972	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1002804001973	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1002804001974	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1002804001975	Walker A/P-loop; other site
1002804001976	ATP binding site [chemical binding]; other site
1002804001977	Q-loop/lid; other site
1002804001978	ABC transporter signature motif; other site
1002804001979	Walker B; other site
1002804001980	D-loop; other site
1002804001981	H-loop/switch region; other site
1002804001982	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1002804001983	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1002804001984	GTP1/OBG; Region: GTP1_OBG; pfam01018
1002804001985	Obg GTPase; Region: Obg; cd01898
1002804001986	G1 box; other site
1002804001987	GTP/Mg2+ binding site [chemical binding]; other site
1002804001988	Switch I region; other site
1002804001989	G2 box; other site
1002804001990	G3 box; other site
1002804001991	Switch II region; other site
1002804001992	G4 box; other site
1002804001993	G5 box; other site
1002804001994	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804001995	binding surface
1002804001996	TPR motif; other site
1002804001997	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804001998	Sel1-like repeats; Region: SEL1; smart00671
1002804001999	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002000	binding surface
1002804002001	TPR motif; other site
1002804002002	Sel1-like repeats; Region: SEL1; smart00671
1002804002003	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002004	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002005	TPR motif; other site
1002804002006	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002007	binding surface
1002804002008	Sel1-like repeats; Region: SEL1; smart00671
1002804002009	Sel1-like repeats; Region: SEL1; smart00671
1002804002010	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002011	binding surface
1002804002012	TPR motif; other site
1002804002013	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002014	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002015	binding surface
1002804002016	TPR motif; other site
1002804002017	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002018	binding surface
1002804002019	TPR motif; other site
1002804002020	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1002804002021	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1002804002022	active site
1002804002023	ATP-binding site [chemical binding]; other site
1002804002024	pantoate-binding site; other site
1002804002025	HXXH motif; other site
1002804002026	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1002804002027	active site
1002804002028	dimer interface [polypeptide binding]; other site
1002804002029	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1002804002030	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1002804002031	homopentamer interface [polypeptide binding]; other site
1002804002032	active site
1002804002033	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
1002804002034	putative RNA binding site [nucleotide binding]; other site
1002804002035	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
1002804002036	biotin synthase; Provisional; Region: PRK08508
1002804002037	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804002038	FeS/SAM binding site; other site
1002804002039	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1002804002040	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002041	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1002804002042	23S rRNA binding site [nucleotide binding]; other site
1002804002043	L21 binding site [polypeptide binding]; other site
1002804002044	L13 binding site [polypeptide binding]; other site
1002804002045	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1002804002046	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1002804002047	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1002804002048	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1002804002049	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
1002804002050	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1002804002051	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1002804002052	active site
1002804002053	dimer interface [polypeptide binding]; other site
1002804002054	motif 1; other site
1002804002055	motif 2; other site
1002804002056	motif 3; other site
1002804002057	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1002804002058	anticodon binding site; other site
1002804002059	recombinase A; Provisional; Region: recA; PRK09354
1002804002060	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1002804002061	hexamer interface [polypeptide binding]; other site
1002804002062	Walker A motif; other site
1002804002063	ATP binding site [chemical binding]; other site
1002804002064	Walker B motif; other site
1002804002065	AMIN domain; Region: AMIN; pfam11741
1002804002066	CTP synthetase; Validated; Region: pyrG; PRK05380
1002804002067	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1002804002068	Catalytic site [active]
1002804002069	active site
1002804002070	UTP binding site [chemical binding]; other site
1002804002071	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1002804002072	active site
1002804002073	putative oxyanion hole; other site
1002804002074	catalytic triad [active]
1002804002075	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1002804002076	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1002804002077	active site
1002804002078	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1002804002079	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1002804002080	motif II; other site
1002804002081	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804002082	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1002804002083	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804002084	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1002804002085	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1002804002086	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804002087	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1002804002088	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1002804002089	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1002804002090	metal-binding site
1002804002091	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804002092	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
1002804002093	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1002804002094	Putative catalytic NodB homology domain of Mesorhizobium loti Mlr8448 protein and its bacterial homologs; Region: CE4_Mlr8448_like_5s; cd10968
1002804002095	putative active site [active]
1002804002096	putative metal binding site [ion binding]; other site
1002804002097	potential frameshift: common BLAST hit: gi|315452506|ref|YP_004072776.1| glutamate-1-semialdehyde 2,1-aminomutase/aminotransferase
1002804002098	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804002099	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804002100	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804002101	catalytic residue [active]
1002804002102	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804002103	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1002804002104	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1002804002105	active site
1002804002106	motif I; other site
1002804002107	motif II; other site
1002804002108	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804002109	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804002110	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1002804002111	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1002804002112	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1002804002113	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1002804002114	potential frameshift: common BLAST hit: gi|315453539|ref|YP_004073809.1| transaldolase
1002804002115	Class I aldolases; Region: Aldolase_Class_I; cl17187
1002804002116	catalytic residue [active]
1002804002117	Class I aldolases; Region: Aldolase_Class_I; cl17187
1002804002118	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1002804002119	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1002804002120	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1002804002121	NifU-like domain; Region: NifU; cl00484
1002804002122	Predicted membrane protein [Function unknown]; Region: COG2855
1002804002123	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1002804002124	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1002804002125	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1002804002126	metal ion-dependent adhesion site (MIDAS); other site
1002804002127	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1002804002128	active site
1002804002129	ATP binding site [chemical binding]; other site
1002804002130	substrate binding site [chemical binding]; other site
1002804002131	activation loop (A-loop); other site
1002804002132	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1002804002133	Phosphate transporter family; Region: PHO4; cl00396
1002804002134	potential frameshift: common BLAST hit: gi|315453825|ref|YP_004074095.1| Magnesium and cobalt efflux protein
1002804002135	Domain of unknown function DUF21; Region: DUF21; pfam01595
1002804002136	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1002804002137	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1002804002138	Transporter associated domain; Region: CorC_HlyC; smart01091
1002804002139	Outer membrane efflux protein; Region: OEP; pfam02321
1002804002140	Outer membrane efflux protein; Region: OEP; pfam02321
1002804002141	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1002804002142	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1002804002143	HlyD family secretion protein; Region: HlyD_3; pfam13437
1002804002144	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1002804002145	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1002804002146	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1002804002147	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1002804002148	AzlC protein; Region: AzlC; cl00570
1002804002149	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1002804002150	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002151	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1002804002152	conserved hypothetical integral membrane protein; Region: TIGR00056
1002804002153	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1002804002154	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1002804002155	Walker A/P-loop; other site
1002804002156	ATP binding site [chemical binding]; other site
1002804002157	Q-loop/lid; other site
1002804002158	ABC transporter signature motif; other site
1002804002159	Walker B; other site
1002804002160	D-loop; other site
1002804002161	H-loop/switch region; other site
1002804002162	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1002804002163	mce related protein; Region: MCE; pfam02470
1002804002164	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002165	Sel1-like repeats; Region: SEL1; smart00671
1002804002166	Sel1-like repeats; Region: SEL1; smart00671
1002804002167	Sel1-like repeats; Region: SEL1; smart00671
1002804002168	Sel1-like repeats; Region: SEL1; smart00671
1002804002169	Sel1-like repeats; Region: SEL1; smart00671
1002804002170	Sel1-like repeats; Region: SEL1; smart00671
1002804002171	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002172	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002173	binding surface
1002804002174	TPR motif; other site
1002804002175	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002176	TPR motif; other site
1002804002177	binding surface
1002804002178	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1002804002179	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1002804002180	putative active site [active]
1002804002181	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1002804002182	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804002183	dimerization interface [polypeptide binding]; other site
1002804002184	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804002185	dimer interface [polypeptide binding]; other site
1002804002186	putative CheW interface [polypeptide binding]; other site
1002804002187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1002804002188	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1002804002189	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002190	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002191	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804002192	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804002193	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1002804002194	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1002804002195	motif II; other site
1002804002196	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1002804002197	active site
1002804002198	Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539
1002804002199	active site
1002804002200	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1002804002201	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1002804002202	dephospho-CoA kinase; Region: TIGR00152
1002804002203	CoA-binding site [chemical binding]; other site
1002804002204	ATP-binding [chemical binding]; other site
1002804002205	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1002804002206	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1002804002207	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1002804002208	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
1002804002209	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804002210	Walker A motif; other site
1002804002211	ATP binding site [chemical binding]; other site
1002804002212	Walker B motif; other site
1002804002213	arginine finger; other site
1002804002214	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1002804002215	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1002804002216	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1002804002217	Walker A/P-loop; other site
1002804002218	ATP binding site [chemical binding]; other site
1002804002219	Q-loop/lid; other site
1002804002220	ABC transporter signature motif; other site
1002804002221	Walker B; other site
1002804002222	D-loop; other site
1002804002223	H-loop/switch region; other site
1002804002224	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1002804002225	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1002804002226	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1002804002227	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
1002804002228	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1002804002229	NAD(P) binding site [chemical binding]; other site
1002804002230	homodimer interface [polypeptide binding]; other site
1002804002231	substrate binding site [chemical binding]; other site
1002804002232	active site
1002804002233	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1002804002234	Flavoprotein; Region: Flavoprotein; pfam02441
1002804002235	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1002804002236	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1002804002237	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1002804002238	RNA binding site [nucleotide binding]; other site
1002804002239	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1002804002240	RNA binding site [nucleotide binding]; other site
1002804002241	S1 RNA binding domain; Region: S1; pfam00575
1002804002242	RNA binding site [nucleotide binding]; other site
1002804002243	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1002804002244	RNA binding site [nucleotide binding]; other site
1002804002245	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
1002804002246	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1002804002247	ligand binding site [chemical binding]; other site
1002804002248	NAD binding site [chemical binding]; other site
1002804002249	dimerization interface [polypeptide binding]; other site
1002804002250	catalytic site [active]
1002804002251	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1002804002252	putative L-serine binding site [chemical binding]; other site
1002804002253	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
1002804002254	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1002804002255	catalytic residue [active]
1002804002256	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1002804002257	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1002804002258	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1002804002259	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1002804002260	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1002804002261	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1002804002262	tetramer interface [polypeptide binding]; other site
1002804002263	active site
1002804002264	Mg2+/Mn2+ binding site [ion binding]; other site
1002804002265	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1002804002266	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1002804002267	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1002804002268	putative trimer interface [polypeptide binding]; other site
1002804002269	putative active site [active]
1002804002270	putative substrate binding site [chemical binding]; other site
1002804002271	putative CoA binding site [chemical binding]; other site
1002804002272	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1002804002273	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804002274	active site
1002804002275	phosphorylation site [posttranslational modification]
1002804002276	intermolecular recognition site; other site
1002804002277	dimerization interface [polypeptide binding]; other site
1002804002278	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
1002804002279	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1002804002280	FtsH Extracellular; Region: FtsH_ext; pfam06480
1002804002281	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1002804002282	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804002283	Walker A motif; other site
1002804002284	ATP binding site [chemical binding]; other site
1002804002285	Walker B motif; other site
1002804002286	arginine finger; other site
1002804002287	Peptidase family M41; Region: Peptidase_M41; pfam01434
1002804002288	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1002804002289	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
1002804002290	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1002804002291	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1002804002292	metal-binding site [ion binding]
1002804002293	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1002804002294	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1002804002295	motif II; other site
1002804002296	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1002804002297	metal-binding site [ion binding]
1002804002298	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1002804002299	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1002804002300	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804002301	Walker A/P-loop; other site
1002804002302	ATP binding site [chemical binding]; other site
1002804002303	Q-loop/lid; other site
1002804002304	ABC transporter signature motif; other site
1002804002305	Walker B; other site
1002804002306	D-loop; other site
1002804002307	H-loop/switch region; other site
1002804002308	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1002804002309	dimerization interface [polypeptide binding]; other site
1002804002310	putative ATP binding site [chemical binding]; other site
1002804002311	serine O-acetyltransferase; Region: cysE; TIGR01172
1002804002312	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1002804002313	trimer interface [polypeptide binding]; other site
1002804002314	active site
1002804002315	substrate binding site [chemical binding]; other site
1002804002316	CoA binding site [chemical binding]; other site
1002804002317	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1002804002318	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1002804002319	dimer interface [polypeptide binding]; other site
1002804002320	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804002321	catalytic residue [active]
1002804002322	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1002804002323	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1002804002324	active site
1002804002325	catalytic tetrad [active]
1002804002326	Response regulator receiver domain; Region: Response_reg; pfam00072
1002804002327	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804002328	active site
1002804002329	phosphorylation site [posttranslational modification]
1002804002330	intermolecular recognition site; other site
1002804002331	dimerization interface [polypeptide binding]; other site
1002804002332	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804002333	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1002804002334	Walker A motif; other site
1002804002335	ATP binding site [chemical binding]; other site
1002804002336	Walker B motif; other site
1002804002337	arginine finger; other site
1002804002338	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804002339	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1002804002340	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1002804002341	DNA gyrase subunit A; Validated; Region: PRK05560
1002804002342	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1002804002343	CAP-like domain; other site
1002804002344	active site
1002804002345	primary dimer interface [polypeptide binding]; other site
1002804002346	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1002804002347	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1002804002348	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1002804002349	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1002804002350	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1002804002351	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1002804002352	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1002804002353	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; cl01409
1002804002354	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002355	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1002804002356	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1002804002357	ssDNA binding site; other site
1002804002358	generic binding surface II; other site
1002804002359	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1002804002360	ATP binding site [chemical binding]; other site
1002804002361	putative Mg++ binding site [ion binding]; other site
1002804002362	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1002804002363	nucleotide binding region [chemical binding]; other site
1002804002364	ATP-binding site [chemical binding]; other site
1002804002365	cbb3-type cytochrome c oxidase subunit I; Provisional; Region: PRK14488
1002804002366	Low-spin heme binding site [chemical binding]; other site
1002804002367	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1002804002368	D-pathway; other site
1002804002369	Putative water exit pathway; other site
1002804002370	Binuclear center (active site) [active]
1002804002371	K-pathway; other site
1002804002372	Putative proton exit pathway; other site
1002804002373	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
1002804002374	cbb3-type cytochrome c oxidase subunit II; Provisional; Region: PRK14487
1002804002375	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
1002804002376	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
1002804002377	Cytochrome c; Region: Cytochrom_C; pfam00034
1002804002378	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1002804002379	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
1002804002380	potential frameshift: common BLAST hit: gi|315453832|ref|YP_004074102.1| putative outer membrane protein
1002804002381	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002382	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002383	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002384	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804002385	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804002386	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804002387	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1002804002388	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
1002804002389	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1002804002390	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1002804002391	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
1002804002392	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1002804002393	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1002804002394	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1002804002395	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804002396	Uncharacterized conserved protein [Function unknown]; Region: COG3472
1002804002397	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1002804002398	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1002804002399	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804002400	S-adenosylmethionine binding site [chemical binding]; other site
1002804002401	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1002804002402	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1002804002403	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1002804002404	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1002804002405	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1002804002406	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1002804002407	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
1002804002408	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1002804002409	HSP70 interaction site [polypeptide binding]; other site
1002804002410	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1002804002411	substrate binding site [polypeptide binding]; other site
1002804002412	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1002804002413	Zn binding sites [ion binding]; other site
1002804002414	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1002804002415	dimer interface [polypeptide binding]; other site
1002804002416	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1002804002417	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1002804002418	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1002804002419	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1002804002420	active site
1002804002421	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1002804002422	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1002804002423	potential frameshift: common BLAST hit: gi|315452712|ref|YP_004072982.1| 1-deoxyxylulose-5-phosphate synthase
1002804002424	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1002804002425	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1002804002426	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1002804002427	TPP-binding site; other site
1002804002428	flagellar assembly protein H; Validated; Region: fliH; PRK06669
1002804002429	Flagellar assembly protein FliH; Region: FliH; pfam02108
1002804002430	flagellar assembly protein H; Validated; Region: fliH; PRK06669
1002804002431	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1002804002432	FliG C-terminal domain; Region: FliG_C; pfam01706
1002804002433	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1002804002434	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1002804002435	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1002804002436	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1002804002437	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1002804002438	active site
1002804002439	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1002804002440	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1002804002441	molybdopterin cofactor binding site; other site
1002804002442	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1002804002443	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1002804002444	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1002804002445	molybdopterin cofactor binding site; other site
1002804002446	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1002804002447	potential frameshift: common BLAST hit: gi|315124306|ref|YP_004066310.1| quinol dehydrogenase membrane component
1002804002448	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1002804002449	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1002804002450	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1002804002451	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1002804002452	Rod binding protein; Region: Rod-binding; cl01626
1002804002453	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1002804002454	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1002804002455	ATP binding site [chemical binding]; other site
1002804002456	Mg2+ binding site [ion binding]; other site
1002804002457	G-X-G motif; other site
1002804002458	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1002804002459	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1002804002460	dimerization interface [polypeptide binding]; other site
1002804002461	DPS ferroxidase diiron center [ion binding]; other site
1002804002462	ion pore; other site
1002804002463	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
1002804002464	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1002804002465	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1002804002466	substrate binding pocket [chemical binding]; other site
1002804002467	chain length determination region; other site
1002804002468	substrate-Mg2+ binding site; other site
1002804002469	catalytic residues [active]
1002804002470	aspartate-rich region 1; other site
1002804002471	active site lid residues [active]
1002804002472	aspartate-rich region 2; other site
1002804002473	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1002804002474	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1002804002475	tRNA; other site
1002804002476	putative tRNA binding site [nucleotide binding]; other site
1002804002477	putative NADP binding site [chemical binding]; other site
1002804002478	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1002804002479	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1002804002480	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1002804002481	dimer interface [polypeptide binding]; other site
1002804002482	motif 1; other site
1002804002483	active site
1002804002484	motif 2; other site
1002804002485	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1002804002486	putative deacylase active site [active]
1002804002487	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1002804002488	active site
1002804002489	motif 3; other site
1002804002490	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1002804002491	anticodon binding site; other site
1002804002492	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1002804002493	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1002804002494	domain interfaces; other site
1002804002495	active site
1002804002496	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1002804002497	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1002804002498	active site
1002804002499	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804002500	DNA methylase; Region: N6_N4_Mtase; pfam01555
1002804002501	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1002804002502	Class II fumarases; Region: Fumarase_classII; cd01362
1002804002503	active site
1002804002504	tetramer interface [polypeptide binding]; other site
1002804002505	YtkA-like; Region: YtkA; pfam13115
1002804002506	Outer membrane efflux protein; Region: OEP; pfam02321
1002804002507	Outer membrane efflux protein; Region: OEP; pfam02321
1002804002508	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1002804002509	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1002804002510	E3 interaction surface; other site
1002804002511	lipoyl attachment site [posttranslational modification]; other site
1002804002512	HlyD family secretion protein; Region: HlyD_3; pfam13437
1002804002513	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1002804002514	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1002804002515	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1002804002516	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
1002804002517	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1002804002518	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1002804002519	active site
1002804002520	carbon storage regulator; Provisional; Region: PRK00568
1002804002521	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
1002804002522	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1002804002523	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1002804002524	SmpB-tmRNA interface; other site
1002804002525	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
1002804002526	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1002804002527	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1002804002528	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1002804002529	RNase P protein component [Translation, ribosomal structure and biogenesis]; Region: RnpA; COG0594
1002804002530	Haemolytic domain; Region: Haemolytic; cl00506
1002804002531	membrane protein insertase; Provisional; Region: PRK01318
1002804002532	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1002804002533	potential frameshift: common BLAST hit: gi|315453616|ref|YP_004073886.1| VirB11-interacting protein
1002804002534	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1002804002535	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1002804002536	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098
1002804002537	G-X-X-G motif; other site
1002804002538	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1002804002539	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1002804002540	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1002804002541	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1002804002542	G1 box; other site
1002804002543	GTP/Mg2+ binding site [chemical binding]; other site
1002804002544	Switch I region; other site
1002804002545	G2 box; other site
1002804002546	Switch II region; other site
1002804002547	G3 box; other site
1002804002548	G4 box; other site
1002804002549	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1002804002550	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002551	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
1002804002552	HD domain; Region: HD_3; pfam13023
1002804002553	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1002804002554	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1002804002555	putative metal binding site [ion binding]; other site
1002804002556	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1002804002557	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1002804002558	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1002804002559	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1002804002560	putative metal binding site [ion binding]; other site
1002804002561	DNA polymerase III subunit beta; Validated; Region: PRK05643
1002804002562	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1002804002563	putative DNA binding surface [nucleotide binding]; other site
1002804002564	dimer interface [polypeptide binding]; other site
1002804002565	beta-clamp/clamp loader binding surface; other site
1002804002566	beta-clamp/translesion DNA polymerase binding surface; other site
1002804002567	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1002804002568	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804002569	Walker A motif; other site
1002804002570	ATP binding site [chemical binding]; other site
1002804002571	Walker B motif; other site
1002804002572	arginine finger; other site
1002804002573	GTP-binding protein Der; Reviewed; Region: PRK00093
1002804002574	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1002804002575	G1 box; other site
1002804002576	GTP/Mg2+ binding site [chemical binding]; other site
1002804002577	G2 box; other site
1002804002578	Switch I region; other site
1002804002579	G3 box; other site
1002804002580	Switch II region; other site
1002804002581	G4 box; other site
1002804002582	G5 box; other site
1002804002583	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1002804002584	G1 box; other site
1002804002585	GTP/Mg2+ binding site [chemical binding]; other site
1002804002586	Switch I region; other site
1002804002587	G2 box; other site
1002804002588	G3 box; other site
1002804002589	Switch II region; other site
1002804002590	G4 box; other site
1002804002591	G5 box; other site
1002804002592	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1002804002593	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1002804002594	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1002804002595	Domain of unknown function DUF87; Region: DUF87; pfam01935
1002804002596	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1002804002597	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1002804002598	putative metal binding site [ion binding]; other site
1002804002599	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
1002804002600	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1002804002601	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
1002804002602	active site
1002804002603	Zn binding site [ion binding]; other site
1002804002604	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002605	fructose-1,6-bisphosphatase; Provisional; Region: PRK09293
1002804002606	active site
1002804002607	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1002804002608	putative active site [active]
1002804002609	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
1002804002610	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1002804002611	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1002804002612	Allophanate hydrolase subunit 2; Region: AHS2; pfam02626
1002804002613	Uncharacterized conserved protein [Function unknown]; Region: COG3287
1002804002614	FIST N domain; Region: FIST; cl10701
1002804002615	FIST C domain; Region: FIST_C; pfam10442
1002804002616	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804002617	dimer interface [polypeptide binding]; other site
1002804002618	putative CheW interface [polypeptide binding]; other site
1002804002619	Lecithin retinol acyltransferase; Region: LRAT; pfam04970
1002804002620	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1002804002621	S17 interaction site [polypeptide binding]; other site
1002804002622	S8 interaction site; other site
1002804002623	16S rRNA interaction site [nucleotide binding]; other site
1002804002624	streptomycin interaction site [chemical binding]; other site
1002804002625	23S rRNA interaction site [nucleotide binding]; other site
1002804002626	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1002804002627	30S ribosomal protein S7; Validated; Region: PRK05302
1002804002628	elongation factor G; Reviewed; Region: PRK00007
1002804002629	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1002804002630	G1 box; other site
1002804002631	putative GEF interaction site [polypeptide binding]; other site
1002804002632	GTP/Mg2+ binding site [chemical binding]; other site
1002804002633	Switch I region; other site
1002804002634	G2 box; other site
1002804002635	G3 box; other site
1002804002636	Switch II region; other site
1002804002637	G4 box; other site
1002804002638	G5 box; other site
1002804002639	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1002804002640	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1002804002641	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1002804002642	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002643	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1002804002644	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1002804002645	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1002804002646	alphaNTD homodimer interface [polypeptide binding]; other site
1002804002647	alphaNTD - beta interaction site [polypeptide binding]; other site
1002804002648	alphaNTD - beta' interaction site [polypeptide binding]; other site
1002804002649	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1002804002650	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1002804002651	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1002804002652	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1002804002653	RNA binding surface [nucleotide binding]; other site
1002804002654	30S ribosomal protein S11; Validated; Region: PRK05309
1002804002655	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1002804002656	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1002804002657	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1002804002658	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1002804002659	rRNA binding site [nucleotide binding]; other site
1002804002660	predicted 30S ribosome binding site; other site
1002804002661	GTPase Era; Reviewed; Region: era; PRK00089
1002804002662	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1002804002663	G1 box; other site
1002804002664	GTP/Mg2+ binding site [chemical binding]; other site
1002804002665	Switch I region; other site
1002804002666	G2 box; other site
1002804002667	Switch II region; other site
1002804002668	G3 box; other site
1002804002669	G4 box; other site
1002804002670	G5 box; other site
1002804002671	KH domain; Region: KH_2; pfam07650
1002804002672	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1002804002673	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804002674	Walker A motif; other site
1002804002675	ATP binding site [chemical binding]; other site
1002804002676	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804002677	Walker B motif; other site
1002804002678	arginine finger; other site
1002804002679	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1002804002680	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1002804002681	active site
1002804002682	HslU subunit interaction site [polypeptide binding]; other site
1002804002683	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1002804002684	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1002804002685	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1002804002686	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002687	Sel1-like repeats; Region: SEL1; smart00671
1002804002688	Sel1-like repeats; Region: SEL1; smart00671
1002804002689	Sel1-like repeats; Region: SEL1; smart00671
1002804002690	Sel1-like repeats; Region: SEL1; smart00671
1002804002691	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
1002804002692	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
1002804002693	putative trimer interface [polypeptide binding]; other site
1002804002694	putative CoA binding site [chemical binding]; other site
1002804002695	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1002804002696	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1002804002697	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1002804002698	recA bacterial DNA recombination protein; Region: RecA; cl17211
1002804002699	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1002804002700	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1002804002701	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1002804002702	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1002804002703	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1002804002704	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1002804002705	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1002804002706	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1002804002707	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1002804002708	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1002804002709	protein-rRNA interface [nucleotide binding]; other site
1002804002710	putative translocon binding site; other site
1002804002711	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1002804002712	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1002804002713	G-X-X-G motif; other site
1002804002714	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1002804002715	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1002804002716	23S rRNA interface [nucleotide binding]; other site
1002804002717	5S rRNA interface [nucleotide binding]; other site
1002804002718	putative antibiotic binding site [chemical binding]; other site
1002804002719	L25 interface [polypeptide binding]; other site
1002804002720	L27 interface [polypeptide binding]; other site
1002804002721	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1002804002722	L23 interface [polypeptide binding]; other site
1002804002723	trigger factor interaction site; other site
1002804002724	23S rRNA interface [nucleotide binding]; other site
1002804002725	Ribosomal protein S17; Region: Ribosomal_S17; cl00351
1002804002726	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1002804002727	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1002804002728	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1002804002729	RNA binding site [nucleotide binding]; other site
1002804002730	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1002804002731	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1002804002732	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1002804002733	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1002804002734	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1002804002735	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1002804002736	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1002804002737	23S rRNA interface [nucleotide binding]; other site
1002804002738	L21e interface [polypeptide binding]; other site
1002804002739	5S rRNA interface [nucleotide binding]; other site
1002804002740	L27 interface [polypeptide binding]; other site
1002804002741	L5 interface [polypeptide binding]; other site
1002804002742	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
1002804002743	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1002804002744	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1002804002745	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1002804002746	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1002804002747	SecY translocase; Region: SecY; pfam00344
1002804002748	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1002804002749	active site
1002804002750	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1002804002751	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
1002804002752	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002753	Sel1-like repeats; Region: SEL1; smart00671
1002804002754	Domain of unknown function(DUF2779); Region: DUF2779; pfam11074
1002804002755	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
1002804002756	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002757	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1002804002758	nickel binding site [ion binding]; other site
1002804002759	putative substrate-binding site; other site
1002804002760	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
1002804002761	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1002804002762	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
1002804002763	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1002804002764	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1002804002765	FkbH-like domain; Region: FkbH; TIGR01686
1002804002766	Acid Phosphatase; Region: Acid_PPase; cl17256
1002804002767	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1002804002768	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1002804002769	active site 2 [active]
1002804002770	active site 1 [active]
1002804002771	classical (c) SDRs; Region: SDR_c; cd05233
1002804002772	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1002804002773	NAD(P) binding site [chemical binding]; other site
1002804002774	active site
1002804002775	potential frameshift: common BLAST hit: gi|315452414|ref|YP_004072684.1| putative Alginate O-acetyltransferase AlgI
1002804002776	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1002804002777	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1002804002778	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1002804002779	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1002804002780	DNA binding residues [nucleotide binding]
1002804002781	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
1002804002782	catalytic residues [active]
1002804002783	catalytic nucleophile [active]
1002804002784	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1002804002785	Probable transposase; Region: OrfB_IS605; pfam01385
1002804002786	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1002804002787	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1002804002788	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
1002804002789	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
1002804002790	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1002804002791	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1002804002792	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1002804002793	NlpC/P60 family; Region: NLPC_P60; cl17555
1002804002794	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1002804002795	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1002804002796	active site
1002804002797	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1002804002798	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1002804002799	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1002804002800	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1002804002801	DNA binding residues [nucleotide binding]
1002804002802	sec-independent translocase; Provisional; Region: tatB; PRK00404
1002804002803	sec-independent translocase; Provisional; Region: PRK04098
1002804002804	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1002804002805	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1002804002806	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1002804002807	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
1002804002808	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1002804002809	urease subunit alpha; Provisional; Region: PRK13986
1002804002810	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1002804002811	alpha-gamma subunit interface [polypeptide binding]; other site
1002804002812	beta-gamma subunit interface [polypeptide binding]; other site
1002804002813	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1002804002814	alpha-beta subunit interface [polypeptide binding]; other site
1002804002815	urease subunit alpha; Reviewed; Region: ureC; PRK13207
1002804002816	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1002804002817	subunit interactions [polypeptide binding]; other site
1002804002818	active site
1002804002819	flap region; other site
1002804002820	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
1002804002821	Urease accessory protein UreE [Posttranslational modification, protein turnover, chaperones]; Region: UreE; COG2371
1002804002822	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
1002804002823	dimer interface [polypeptide binding]; other site
1002804002824	catalytic residues [active]
1002804002825	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
1002804002826	UreF; Region: UreF; pfam01730
1002804002827	urease accessory protein UreG; Region: ureG; TIGR00101
1002804002828	UreD urease accessory protein; Region: UreD; cl00530
1002804002829	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1002804002830	Ligand Binding Site [chemical binding]; other site
1002804002831	Integral membrane protein TerC family; Region: TerC; cl10468
1002804002832	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
1002804002833	active site 1 [active]
1002804002834	dimer interface [polypeptide binding]; other site
1002804002835	hexamer interface [polypeptide binding]; other site
1002804002836	active site 2 [active]
1002804002837	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1002804002838	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1002804002839	non-specific DNA binding site [nucleotide binding]; other site
1002804002840	salt bridge; other site
1002804002841	sequence-specific DNA binding site [nucleotide binding]; other site
1002804002842	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1002804002843	Catalytic site [active]
1002804002844	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
1002804002845	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1002804002846	Seven times multi-haem cytochrome CxxCH; Region: Multi-haem_cyto; pfam13447
1002804002847	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; cl01409
1002804002848	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1002804002849	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1002804002850	dimer interface [polypeptide binding]; other site
1002804002851	phosphorylation site [posttranslational modification]
1002804002852	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1002804002853	ATP binding site [chemical binding]; other site
1002804002854	Mg2+ binding site [ion binding]; other site
1002804002855	G-X-G motif; other site
1002804002856	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1002804002857	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804002858	active site
1002804002859	phosphorylation site [posttranslational modification]
1002804002860	intermolecular recognition site; other site
1002804002861	dimerization interface [polypeptide binding]; other site
1002804002862	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1002804002863	DNA binding site [nucleotide binding]
1002804002864	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1002804002865	RNA/DNA hybrid binding site [nucleotide binding]; other site
1002804002866	active site
1002804002867	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002868	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1002804002869	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1002804002870	N-terminal plug; other site
1002804002871	ligand-binding site [chemical binding]; other site
1002804002872	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
1002804002873	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1002804002874	nucleotide binding site/active site [active]
1002804002875	HIT family signature motif; other site
1002804002876	catalytic residue [active]
1002804002877	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1002804002878	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804002879	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804002880	catalytic residue [active]
1002804002881	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
1002804002882	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1002804002883	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1002804002884	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1002804002885	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1002804002886	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1002804002887	putative active site [active]
1002804002888	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1002804002889	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1002804002890	putative acyl-acceptor binding pocket; other site
1002804002891	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804002892	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1002804002893	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1002804002894	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804002895	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1002804002896	potential frameshift: common BLAST hit: gi|315452538|ref|YP_004072808.1| outer membrane protein HorA
1002804002897	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002898	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002899	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1002804002900	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1002804002901	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1002804002902	molybdopterin cofactor binding site [chemical binding]; other site
1002804002903	substrate binding site [chemical binding]; other site
1002804002904	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1002804002905	molybdopterin cofactor binding site; other site
1002804002906	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1002804002907	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1002804002908	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1002804002909	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1002804002910	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1002804002911	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1002804002912	metal binding site [ion binding]; metal-binding site
1002804002913	dimer interface [polypeptide binding]; other site
1002804002914	DsrE/DsrF-like family; Region: DrsE; cl00672
1002804002915	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1002804002916	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804002917	active site
1002804002918	phosphorylation site [posttranslational modification]
1002804002919	intermolecular recognition site; other site
1002804002920	dimerization interface [polypeptide binding]; other site
1002804002921	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1002804002922	DNA binding site [nucleotide binding]
1002804002923	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
1002804002924	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1002804002925	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1002804002926	active site
1002804002927	HIGH motif; other site
1002804002928	KMSK motif region; other site
1002804002929	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1002804002930	tRNA binding surface [nucleotide binding]; other site
1002804002931	anticodon binding site; other site
1002804002932	mttA/Hcf106 family; Region: MttA_Hcf106; pfam02416
1002804002933	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1002804002934	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1002804002935	catalytic site [active]
1002804002936	G-X2-G-X-G-K; other site
1002804002937	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
1002804002938	PLD-like domain; Region: PLDc_2; pfam13091
1002804002939	putative active site [active]
1002804002940	catalytic site [active]
1002804002941	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002942	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1002804002943	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1002804002944	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1002804002945	ligand binding site; other site
1002804002946	tetramer interface; other site
1002804002947	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
1002804002948	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
1002804002949	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
1002804002950	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1002804002951	NeuB family; Region: NeuB; pfam03102
1002804002952	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1002804002953	NeuB binding interface [polypeptide binding]; other site
1002804002954	putative substrate binding site [chemical binding]; other site
1002804002955	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1002804002956	metal binding site 2 [ion binding]; metal-binding site
1002804002957	putative DNA binding helix; other site
1002804002958	metal binding site 1 [ion binding]; metal-binding site
1002804002959	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804002960	dimer interface [polypeptide binding]; other site
1002804002961	putative CheW interface [polypeptide binding]; other site
1002804002962	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1002804002963	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
1002804002964	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804002965	catalytic residue [active]
1002804002966	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
1002804002967	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1002804002968	metal-binding site
1002804002969	transferase, transferring glycosyl groups; Region: PLN02939
1002804002970	potential frameshift: common BLAST hit: gi|315453797|ref|YP_004074067.1| phage-related CUP0950-like protein
1002804002971	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002972	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1002804002973	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1002804002974	dimer interface [polypeptide binding]; other site
1002804002975	conserved gate region; other site
1002804002976	putative PBP binding loops; other site
1002804002977	ABC-ATPase subunit interface; other site
1002804002978	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1002804002979	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1002804002980	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
1002804002981	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1002804002982	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cl00522
1002804002983	active site
1002804002984	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804002985	Sel1-like repeats; Region: SEL1; smart00671
1002804002986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804002987	TPR motif; other site
1002804002988	binding surface
1002804002989	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1002804002990	ThiS interaction site; other site
1002804002991	putative active site [active]
1002804002992	tetramer interface [polypeptide binding]; other site
1002804002993	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804002994	S-adenosylmethionine binding site [chemical binding]; other site
1002804002995	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1002804002996	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1002804002997	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1002804002998	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804002999	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1002804003000	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1002804003001	5S rRNA interface [nucleotide binding]; other site
1002804003002	CTC domain interface [polypeptide binding]; other site
1002804003003	L16 interface [polypeptide binding]; other site
1002804003004	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1002804003005	putative active site [active]
1002804003006	catalytic residue [active]
1002804003007	Predicted permeases [General function prediction only]; Region: COG0795
1002804003008	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1002804003009	Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA; cl00012
1002804003010	active site
1002804003011	zinc binding site [ion binding]; other site
1002804003012	Flagellin N-methylase; Region: FliB; pfam03692
1002804003013	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
1002804003014	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804003015	Walker A motif; other site
1002804003016	ATP binding site [chemical binding]; other site
1002804003017	Walker B motif; other site
1002804003018	arginine finger; other site
1002804003019	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1002804003020	dimerization interface [polypeptide binding]; other site
1002804003021	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1002804003022	ATP binding site [chemical binding]; other site
1002804003023	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1002804003024	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1002804003025	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1002804003026	Acylphosphatase; Region: Acylphosphatase; pfam00708
1002804003027	HypF finger; Region: zf-HYPF; pfam07503
1002804003028	HypF finger; Region: zf-HYPF; pfam07503
1002804003029	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1002804003030	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1002804003031	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1002804003032	UGMP family protein; Validated; Region: PRK09604
1002804003033	Protein of unknown function (DUF3365); Region: DUF3365; pfam11845
1002804003034	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804003035	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1002804003036	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804003037	dimer interface [polypeptide binding]; other site
1002804003038	putative CheW interface [polypeptide binding]; other site
1002804003039	formamidase; Provisional; Region: amiF; PRK13287
1002804003040	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1002804003041	multimer interface [polypeptide binding]; other site
1002804003042	active site
1002804003043	catalytic triad [active]
1002804003044	dimer interface [polypeptide binding]; other site
1002804003045	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1002804003046	Ferritin-like domain; Region: Ferritin; pfam00210
1002804003047	ferroxidase diiron center [ion binding]; other site
1002804003048	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1002804003049	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1002804003050	G1 box; other site
1002804003051	GTP/Mg2+ binding site [chemical binding]; other site
1002804003052	Switch I region; other site
1002804003053	G2 box; other site
1002804003054	G3 box; other site
1002804003055	Switch II region; other site
1002804003056	G4 box; other site
1002804003057	G5 box; other site
1002804003058	Nucleoside recognition; Region: Gate; pfam07670
1002804003059	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1002804003060	Nucleoside recognition; Region: Gate; pfam07670
1002804003061	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1002804003062	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1002804003063	RNA binding surface [nucleotide binding]; other site
1002804003064	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1002804003065	active site
1002804003066	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1002804003067	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
1002804003068	Interdomain contacts; other site
1002804003069	Cytokine receptor motif; other site
1002804003070	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1002804003071	Interdomain contacts; other site
1002804003072	Cytokine receptor motif; other site
1002804003073	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1002804003074	Interdomain contacts; other site
1002804003075	Cytokine receptor motif; other site
1002804003076	Putative methyltransferase; Region: Methyltransf_4; cl17290
1002804003077	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1002804003078	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1002804003079	Walker A/P-loop; other site
1002804003080	ATP binding site [chemical binding]; other site
1002804003081	Q-loop/lid; other site
1002804003082	ABC transporter signature motif; other site
1002804003083	Walker B; other site
1002804003084	D-loop; other site
1002804003085	H-loop/switch region; other site
1002804003086	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1002804003087	Peptidase family M23; Region: Peptidase_M23; pfam01551
1002804003088	FlaG protein; Region: FlaG; cl00591
1002804003089	flagellar capping protein; Validated; Region: fliD; PRK08453
1002804003090	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1002804003091	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1002804003092	flagellar protein FliS; Validated; Region: fliS; PRK05685
1002804003093	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003094	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
1002804003095	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1002804003096	HlyD family secretion protein; Region: HlyD_3; pfam13437
1002804003097	potential frameshift: common BLAST hit: gi|315453213|ref|YP_004073483.1| putative outer membrane component of efflux system
1002804003098	Outer membrane efflux protein; Region: OEP; pfam02321
1002804003099	Outer membrane efflux protein; Region: OEP; pfam02321
1002804003100	Outer membrane efflux protein; Region: OEP; pfam02321
1002804003101	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1002804003102	IHF - DNA interface [nucleotide binding]; other site
1002804003103	IHF dimer interface [polypeptide binding]; other site
1002804003104	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1002804003105	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1002804003106	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1002804003107	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1002804003108	Phosphoglycerate kinase; Region: PGK; pfam00162
1002804003109	substrate binding site [chemical binding]; other site
1002804003110	hinge regions; other site
1002804003111	ADP binding site [chemical binding]; other site
1002804003112	catalytic site [active]
1002804003113	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1002804003114	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1002804003115	oligomer interface [polypeptide binding]; other site
1002804003116	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
1002804003117	potential frameshift: common BLAST hit: gi|315453219|ref|YP_004073489.1| Glutathionylspermidine synthase
1002804003118	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; cl00503
1002804003119	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; cl00503
1002804003120	hypothetical protein; Provisional; Region: PRK04081
1002804003121	potential frameshift: common BLAST hit: gi|315453485|ref|YP_004073755.1| outer membrane protein
1002804003122	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003123	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003124	thiamine monophosphate kinase; Provisional; Region: PRK05731
1002804003125	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1002804003126	ATP binding site [chemical binding]; other site
1002804003127	dimerization interface [polypeptide binding]; other site
1002804003128	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
1002804003129	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1002804003130	dimerization interface [polypeptide binding]; other site
1002804003131	active site
1002804003132	quinolinate synthetase; Provisional; Region: PRK09375
1002804003133	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
1002804003134	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1002804003135	UbiA prenyltransferase family; Region: UbiA; pfam01040
1002804003136	Competence protein; Region: Competence; pfam03772
1002804003137	replicative DNA helicase; Provisional; Region: PRK08506
1002804003138	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1002804003139	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1002804003140	Walker A motif; other site
1002804003141	ATP binding site [chemical binding]; other site
1002804003142	Walker B motif; other site
1002804003143	DNA binding loops [nucleotide binding]
1002804003144	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1002804003145	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1002804003146	putative substrate binding site [chemical binding]; other site
1002804003147	putative ATP binding site [chemical binding]; other site
1002804003148	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
1002804003149	active site
1002804003150	catalytic site [active]
1002804003151	substrate binding site [chemical binding]; other site
1002804003152	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
1002804003153	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1002804003154	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1002804003155	active site
1002804003156	HIGH motif; other site
1002804003157	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1002804003158	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1002804003159	active site
1002804003160	KMSKS motif; other site
1002804003161	potential frameshift: common BLAST hit: gi|315453533|ref|YP_004073803.1| transketolase
1002804003162	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1002804003163	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1002804003164	TPP-binding site [chemical binding]; other site
1002804003165	dimer interface [polypeptide binding]; other site
1002804003166	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1002804003167	PYR/PP interface [polypeptide binding]; other site
1002804003168	dimer interface [polypeptide binding]; other site
1002804003169	TPP binding site [chemical binding]; other site
1002804003170	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1002804003171	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
1002804003172	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1002804003173	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1002804003174	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1002804003175	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
1002804003176	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1002804003177	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1002804003178	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1002804003179	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1002804003180	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1002804003181	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1002804003182	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1002804003183	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1002804003184	tetramer interfaces [polypeptide binding]; other site
1002804003185	binuclear metal-binding site [ion binding]; other site
1002804003186	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1002804003187	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1002804003188	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1002804003189	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1002804003190	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1002804003191	nucleotide binding site [chemical binding]; other site
1002804003192	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
1002804003193	AAA domain; Region: AAA_32; pfam13654
1002804003194	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1002804003195	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
1002804003196	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
1002804003197	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1002804003198	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1002804003199	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
1002804003200	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1002804003201	DNA primase (bacterial type) [DNA replication, recombination, and repair]; Region: DnaG; COG0358
1002804003202	CHC2 zinc finger; Region: zf-CHC2; cl17510
1002804003203	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1002804003204	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1002804003205	active site
1002804003206	metal binding site [ion binding]; metal-binding site
1002804003207	interdomain interaction site; other site
1002804003208	SIR2-like domain; Region: SIR2_2; pfam13289
1002804003209	DNA methylase; Region: N6_N4_Mtase; cl17433
1002804003210	DNA methylase; Region: N6_N4_Mtase; cl17433
1002804003211	Domain of unknown function DUF87; Region: DUF87; pfam01935
1002804003212	HerA helicase [Replication, recombination, and repair]; Region: COG0433
1002804003213	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1002804003214	active site
1002804003215	homotetramer interface [polypeptide binding]; other site
1002804003216	homodimer interface [polypeptide binding]; other site
1002804003217	heat-inducible transcription repressor; Provisional; Region: PRK03911
1002804003218	GrpE; Region: GrpE; pfam01025
1002804003219	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1002804003220	dimer interface [polypeptide binding]; other site
1002804003221	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1002804003222	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1002804003223	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1002804003224	nucleotide binding site [chemical binding]; other site
1002804003225	NEF interaction site [polypeptide binding]; other site
1002804003226	SBD interface [polypeptide binding]; other site
1002804003227	potential frameshift: common BLAST hit: gi|315452588|ref|YP_004072858.1| cytidine monophosphate-N-acetylneuraminic acid
1002804003228	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1002804003229	iron-sulfur cluster [ion binding]; other site
1002804003230	[2Fe-2S] cluster binding site [ion binding]; other site
1002804003231	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1002804003232	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1002804003233	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1002804003234	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1002804003235	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1002804003236	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1002804003237	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1002804003238	tetramer interface [polypeptide binding]; other site
1002804003239	heme binding pocket [chemical binding]; other site
1002804003240	NADPH binding site [chemical binding]; other site
1002804003241	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1002804003242	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1002804003243	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1002804003244	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804003245	dimer interface [polypeptide binding]; other site
1002804003246	putative CheW interface [polypeptide binding]; other site
1002804003247	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1002804003248	PAS domain; Region: PAS_9; pfam13426
1002804003249	putative active site [active]
1002804003250	heme pocket [chemical binding]; other site
1002804003251	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1002804003252	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1002804003253	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
1002804003254	substrate binding pocket [chemical binding]; other site
1002804003255	active site
1002804003256	iron coordination sites [ion binding]; other site
1002804003257	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1002804003258	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1002804003259	succinic semialdehyde dehydrogenase; Region: PLN02278
1002804003260	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1002804003261	tetramerization interface [polypeptide binding]; other site
1002804003262	NAD(P) binding site [chemical binding]; other site
1002804003263	catalytic residues [active]
1002804003264	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
1002804003265	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1002804003266	inhibitor-cofactor binding pocket; inhibition site
1002804003267	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804003268	catalytic residue [active]
1002804003269	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804003270	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1002804003271	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1002804003272	CoA binding domain; Region: CoA_binding; cl17356
1002804003273	comF family protein; Region: comF; TIGR00201
1002804003274	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1002804003275	active site
1002804003276	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1002804003277	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1002804003278	homodimer interface [polypeptide binding]; other site
1002804003279	substrate-cofactor binding pocket; other site
1002804003280	catalytic residue [active]
1002804003281	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1002804003282	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1002804003283	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1002804003284	active site
1002804003285	multimer interface [polypeptide binding]; other site
1002804003286	Ribosomal L32p protein family; Region: Ribosomal_L32p; cl09115
1002804003287	Fatty acid synthesis protein; Region: FA_synthesis; cl17261
1002804003288	putative phosphate acyltransferase; Provisional; Region: PRK05331
1002804003289	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1002804003290	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1002804003291	dimer interface [polypeptide binding]; other site
1002804003292	active site
1002804003293	CoA binding pocket [chemical binding]; other site
1002804003294	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1002804003295	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1002804003296	KH domain; Region: KH_4; pfam13083
1002804003297	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
1002804003298	PRC-barrel domain; Region: PRC; pfam05239
1002804003299	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1002804003300	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1002804003301	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1002804003302	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1002804003303	VirB7 interaction site; other site
1002804003304	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1002804003305	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1002804003306	Cysteine-rich domain; Region: CCG; pfam02754
1002804003307	Cysteine-rich domain; Region: CCG; pfam02754
1002804003308	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1002804003309	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1002804003310	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1002804003311	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1002804003312	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1002804003313	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1002804003314	catalytic triad [active]
1002804003315	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1002804003316	thiS-thiF/thiG interaction site; other site
1002804003317	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1002804003318	putative active site [active]
1002804003319	putative metal binding site [ion binding]; other site
1002804003320	phosphoglyceromutase; Provisional; Region: PRK05434
1002804003321	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1002804003322	potential frameshift: common BLAST hit: gi|315453371|ref|YP_004073641.1| glycyl-tRNA synthetase beta chain
1002804003323	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1002804003324	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1002804003325	Outer membrane efflux protein; Region: OEP; pfam02321
1002804003326	Outer membrane efflux protein; Region: OEP; pfam02321
1002804003327	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1002804003328	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1002804003329	HlyD family secretion protein; Region: HlyD_3; pfam13437
1002804003330	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1002804003331	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1002804003332	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1002804003333	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1002804003334	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1002804003335	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1002804003336	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
1002804003337	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
1002804003338	SelR domain; Region: SelR; pfam01641
1002804003339	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1002804003340	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1002804003341	putative active site [active]
1002804003342	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1002804003343	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
1002804003344	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1002804003345	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1002804003346	glutaminase active site [active]
1002804003347	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1002804003348	dimer interface [polypeptide binding]; other site
1002804003349	active site
1002804003350	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1002804003351	dimer interface [polypeptide binding]; other site
1002804003352	active site
1002804003353	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
1002804003354	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804003355	FeS/SAM binding site; other site
1002804003356	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1002804003357	rod shape-determining protein MreC; Provisional; Region: PRK13922
1002804003358	rod shape-determining protein MreC; Region: MreC; pfam04085
1002804003359	rod shape-determining protein MreB; Provisional; Region: PRK13927
1002804003360	MreB and similar proteins; Region: MreB_like; cd10225
1002804003361	nucleotide binding site [chemical binding]; other site
1002804003362	Mg binding site [ion binding]; other site
1002804003363	putative protofilament interaction site [polypeptide binding]; other site
1002804003364	RodZ interaction site [polypeptide binding]; other site
1002804003365	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1002804003366	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
1002804003367	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804003368	Walker A motif; other site
1002804003369	ATP binding site [chemical binding]; other site
1002804003370	Walker B motif; other site
1002804003371	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1002804003372	potential frameshift: common BLAST hit: gi|315453104|ref|YP_004073374.1| Acyl-[acyl-carrier-protein]--UDP-N-acetylglucos amine
1002804003373	Udp N-acetylglucosamine O-acyltransferase; Domain 2; Region: Acetyltransf_11; pfam13720
1002804003374	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1002804003375	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1002804003376	active site
1002804003377	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1002804003378	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1002804003379	substrate binding site [chemical binding]; other site
1002804003380	potential frameshift: common BLAST hit: gi|315453101|ref|YP_004073371.1| thioredoxin reductase, TrxB
1002804003381	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1002804003382	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1002804003383	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1002804003384	Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: AlaS; COG0013
1002804003385	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1002804003386	motif 1; other site
1002804003387	active site
1002804003388	motif 2; other site
1002804003389	motif 3; other site
1002804003390	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1002804003391	glutamate racemase; Provisional; Region: PRK00865
1002804003392	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1002804003393	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1002804003394	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1002804003395	RNA binding site [nucleotide binding]; other site
1002804003396	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1002804003397	multimer interface [polypeptide binding]; other site
1002804003398	Walker A motif; other site
1002804003399	ATP binding site [chemical binding]; other site
1002804003400	Walker B motif; other site
1002804003401	potential frameshift: common BLAST hit: gi|315452579|ref|YP_004072849.1| putative Cytochrome C assembly protein
1002804003402	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1002804003403	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1002804003404	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
1002804003405	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1002804003406	catalytic residues [active]
1002804003407	ferrochelatase; Reviewed; Region: hemH; PRK00035
1002804003408	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1002804003409	C-terminal domain interface [polypeptide binding]; other site
1002804003410	active site
1002804003411	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1002804003412	active site
1002804003413	N-terminal domain interface [polypeptide binding]; other site
1002804003414	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1002804003415	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1002804003416	N-terminal plug; other site
1002804003417	ligand-binding site [chemical binding]; other site
1002804003418	prefoldin subunit beta; Provisional; Region: PRK09343
1002804003419	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1002804003420	LytB protein; Region: LYTB; pfam02401
1002804003421	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1002804003422	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1002804003423	hinge; other site
1002804003424	active site
1002804003425	potential frameshift: common BLAST hit: gi|315453350|ref|YP_004073620.1| phenylalanyl-tRNA synthetase beta chain
1002804003426	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; cl08386
1002804003427	tRNA synthetase B5 domain; Region: B5; smart00874
1002804003428	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1002804003429	motif 1; other site
1002804003430	dimer interface [polypeptide binding]; other site
1002804003431	active site
1002804003432	motif 2; other site
1002804003433	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1002804003434	putative tRNA-binding site [nucleotide binding]; other site
1002804003435	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1002804003436	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1002804003437	dimer interface [polypeptide binding]; other site
1002804003438	motif 1; other site
1002804003439	active site
1002804003440	motif 2; other site
1002804003441	motif 3; other site
1002804003442	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1002804003443	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
1002804003444	DHH family; Region: DHH; pfam01368
1002804003445	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1002804003446	FHIPEP family; Region: FHIPEP; pfam00771
1002804003447	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1002804003448	16S/18S rRNA binding site [nucleotide binding]; other site
1002804003449	S13e-L30e interaction site [polypeptide binding]; other site
1002804003450	25S rRNA binding site [nucleotide binding]; other site
1002804003451	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1002804003452	O-Antigen ligase; Region: Wzy_C; pfam04932
1002804003453	potential frameshift: common BLAST hit: gi|315452414|ref|YP_004072684.1| putative Alginate O-acetyltransferase AlgI
1002804003454	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1002804003455	MBOAT, membrane-bound O-acyltransferase family; Region: MBOAT; cl00738
1002804003456	classical (c) SDRs; Region: SDR_c; cd05233
1002804003457	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1002804003458	NAD(P) binding site [chemical binding]; other site
1002804003459	active site
1002804003460	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1002804003461	active site 2 [active]
1002804003462	active site 1 [active]
1002804003463	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1002804003464	FkbH-like domain; Region: FkbH; TIGR01686
1002804003465	Acid Phosphatase; Region: Acid_PPase; cl17256
1002804003466	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1002804003467	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1002804003468	Na binding site [ion binding]; other site
1002804003469	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1002804003470	Protein of unknown function, DUF485; Region: DUF485; pfam04341
1002804003471	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1002804003472	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1002804003473	active site
1002804003474	intersubunit interface [polypeptide binding]; other site
1002804003475	catalytic residue [active]
1002804003476	phosphogluconate dehydratase; Validated; Region: PRK09054
1002804003477	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1002804003478	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1002804003479	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1002804003480	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1002804003481	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1002804003482	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
1002804003483	putative active site [active]
1002804003484	glucokinase; Provisional; Region: glk; PRK00292
1002804003485	glucokinase, proteobacterial type; Region: glk; TIGR00749
1002804003486	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1002804003487	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1002804003488	active site
1002804003489	dimer interface [polypeptide binding]; other site
1002804003490	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1002804003491	dimer interface [polypeptide binding]; other site
1002804003492	active site
1002804003493	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1002804003494	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1002804003495	putative substrate translocation pore; other site
1002804003496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1002804003497	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1002804003498	putative substrate translocation pore; other site
1002804003499	Peroxin-3; Region: Peroxin-3; pfam04882
1002804003500	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1002804003501	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1002804003502	tandem repeat interface [polypeptide binding]; other site
1002804003503	oligomer interface [polypeptide binding]; other site
1002804003504	active site residues [active]
1002804003505	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003506	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
1002804003507	S-methylmethionine transporter; Provisional; Region: PRK11387
1002804003508	potential frameshift: common BLAST hit: gi|315452560|ref|YP_004072830.1| iron-sulfur cluster-binding domain-containing protein
1002804003509	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1002804003510	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1002804003511	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1002804003512	molybdopterin cofactor binding site; other site
1002804003513	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1002804003514	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1002804003515	molybdopterin cofactor binding site; other site
1002804003516	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1002804003517	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1002804003518	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1002804003519	Lecithin retinol acyltransferase; Region: LRAT; pfam04970
1002804003520	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1002804003521	MerR family regulatory protein; Region: MerR; pfam00376
1002804003522	DNA binding residues [nucleotide binding]
1002804003523	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
1002804003524	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1002804003525	catalytic residues [active]
1002804003526	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1002804003527	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
1002804003528	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1002804003529	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804003530	dimer interface [polypeptide binding]; other site
1002804003531	putative CheW interface [polypeptide binding]; other site
1002804003532	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1002804003533	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1002804003534	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
1002804003535	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1002804003536	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1002804003537	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1002804003538	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1002804003539	Mg++ binding site [ion binding]; other site
1002804003540	putative catalytic motif [active]
1002804003541	putative substrate binding site [chemical binding]; other site
1002804003542	META domain; Region: META; cl01245
1002804003543	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1002804003544	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
1002804003545	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1002804003546	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1002804003547	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1002804003548	active site
1002804003549	catalytic triad [active]
1002804003550	dimer interface [polypeptide binding]; other site
1002804003551	seryl-tRNA synthetase; Provisional; Region: PRK05431
1002804003552	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1002804003553	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1002804003554	dimer interface [polypeptide binding]; other site
1002804003555	active site
1002804003556	motif 1; other site
1002804003557	motif 2; other site
1002804003558	motif 3; other site
1002804003559	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
1002804003560	TPR repeat; Region: TPR_11; pfam13414
1002804003561	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804003562	TPR motif; other site
1002804003563	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1002804003564	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1002804003565	Family description; Region: UvrD_C_2; pfam13538
1002804003566	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
1002804003567	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1002804003568	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1002804003569	Flavoprotein; Region: Flavoprotein; pfam02441
1002804003570	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1002804003571	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1002804003572	active site
1002804003573	(T/H)XGH motif; other site
1002804003574	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1002804003575	thymidylate kinase; Validated; Region: tmk; PRK00698
1002804003576	TMP-binding site; other site
1002804003577	ATP-binding site [chemical binding]; other site
1002804003578	potential frameshift: common BLAST hit: gi|315452819|ref|YP_004073089.1| L-serine dehydratase/ deaminase 1
1002804003579	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1002804003580	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1002804003581	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1002804003582	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1002804003583	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1002804003584	dihydropteroate synthase; Region: DHPS; TIGR01496
1002804003585	substrate binding pocket [chemical binding]; other site
1002804003586	dimer interface [polypeptide binding]; other site
1002804003587	inhibitor binding site; inhibition site
1002804003588	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1002804003589	DNA replication regulator; Region: HobA; pfam12163
1002804003590	aspartate kinase; Reviewed; Region: PRK06635
1002804003591	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
1002804003592	putative catalytic residues [active]
1002804003593	putative nucleotide binding site [chemical binding]; other site
1002804003594	putative aspartate binding site [chemical binding]; other site
1002804003595	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1002804003596	putative allosteric regulatory site; other site
1002804003597	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1002804003598	putative allosteric regulatory residue; other site
1002804003599	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1002804003600	putative active site [active]
1002804003601	Ap4A binding site [chemical binding]; other site
1002804003602	nudix motif; other site
1002804003603	putative metal binding site [ion binding]; other site
1002804003604	Cytochrome c; Region: Cytochrom_C; cl11414
1002804003605	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
1002804003606	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804003607	FeS/SAM binding site; other site
1002804003608	HemN C-terminal domain; Region: HemN_C; pfam06969
1002804003609	flagellin A; Reviewed; Region: PRK12584
1002804003610	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1002804003611	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1002804003612	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1002804003613	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1002804003614	potential frameshift: common BLAST hit: gi|315452809|ref|YP_004073079.1| acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
1002804003615	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1002804003616	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1002804003617	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; pfam03255
1002804003618	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
1002804003619	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1002804003620	dimer interface [polypeptide binding]; other site
1002804003621	active site
1002804003622	acyl carrier protein; Provisional; Region: acpP; PRK00982
1002804003623	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1002804003624	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1002804003625	NAD(P) binding site [chemical binding]; other site
1002804003626	homotetramer interface [polypeptide binding]; other site
1002804003627	homodimer interface [polypeptide binding]; other site
1002804003628	active site
1002804003629	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1002804003630	glutamate dehydrogenase; Provisional; Region: PRK09414
1002804003631	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1002804003632	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1002804003633	NAD(P) binding site [chemical binding]; other site
1002804003634	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1002804003635	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1002804003636	RF-1 domain; Region: RF-1; pfam00472
1002804003637	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1002804003638	Peptidase family U32; Region: Peptidase_U32; pfam01136
1002804003639	potential frameshift: common BLAST hit: gi|315452801|ref|YP_004073071.1| outer membrane protein
1002804003640	AAA domain; Region: AAA_13; pfam13166
1002804003641	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1002804003642	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1002804003643	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1002804003644	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1002804003645	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1002804003646	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003647	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1002804003648	potential frameshift: common BLAST hit: gi|315453642|ref|YP_004073912.1| UDP-N-acetylglucosamine pyrophosphorylase
1002804003649	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1002804003650	active site
1002804003651	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1002804003652	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1002804003653	active site
1002804003654	substrate binding site [chemical binding]; other site
1002804003655	CoA binding site [chemical binding]; other site
1002804003656	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1002804003657	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
1002804003658	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003659	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804003660	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1002804003661	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1002804003662	G1 box; other site
1002804003663	GTP/Mg2+ binding site [chemical binding]; other site
1002804003664	G2 box; other site
1002804003665	Switch I region; other site
1002804003666	G3 box; other site
1002804003667	Switch II region; other site
1002804003668	G4 box; other site
1002804003669	G5 box; other site
1002804003670	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1002804003671	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
1002804003672	G1 box; other site
1002804003673	GTP/Mg2+ binding site [chemical binding]; other site
1002804003674	potential frameshift: common BLAST hit: gi|315453077|ref|YP_004073347.1| putative thiamine pyrophosphate enzyme (TPP)
1002804003675	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1002804003676	TPP-binding site [chemical binding]; other site
1002804003677	dimer interface [polypeptide binding]; other site
1002804003678	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
1002804003679	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1002804003680	dimer interface [polypeptide binding]; other site
1002804003681	PYR/PP interface [polypeptide binding]; other site
1002804003682	TPP binding site [chemical binding]; other site
1002804003683	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1002804003684	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1002804003685	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1002804003686	substrate binding site [chemical binding]; other site
1002804003687	active site
1002804003688	catalytic residues [active]
1002804003689	heterodimer interface [polypeptide binding]; other site
1002804003690	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1002804003691	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1002804003692	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804003693	catalytic residue [active]
1002804003694	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1002804003695	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1002804003696	active site
1002804003697	ribulose/triose binding site [chemical binding]; other site
1002804003698	phosphate binding site [ion binding]; other site
1002804003699	substrate (anthranilate) binding pocket [chemical binding]; other site
1002804003700	product (indole) binding pocket [chemical binding]; other site
1002804003701	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1002804003702	active site
1002804003703	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1002804003704	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1002804003705	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1002804003706	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1002804003707	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1002804003708	glutamine binding [chemical binding]; other site
1002804003709	catalytic triad [active]
1002804003710	anthranilate synthase component I; Provisional; Region: PRK13564
1002804003711	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1002804003712	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1002804003713	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1002804003714	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1002804003715	inhibitor-cofactor binding pocket; inhibition site
1002804003716	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804003717	catalytic residue [active]
1002804003718	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1002804003719	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
1002804003720	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1002804003721	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1002804003722	metal-binding site [ion binding]
1002804003723	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1002804003724	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1002804003725	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1002804003726	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804003727	S-adenosylmethionine binding site [chemical binding]; other site
1002804003728	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1002804003729	catalytic motif [active]
1002804003730	Zn binding site [ion binding]; other site
1002804003731	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1002804003732	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1002804003733	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1002804003734	NAD(P) binding pocket [chemical binding]; other site
1002804003735	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804003736	DNA methylase; Region: N6_N4_Mtase; pfam01555
1002804003737	putative inner membrane protein; Provisional; Region: PRK11099
1002804003738	putative inner membrane protein; Provisional; Region: PRK11099
1002804003739	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1002804003740	active site
1002804003741	dimerization interface [polypeptide binding]; other site
1002804003742	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1002804003743	putative substrate translocation pore; other site
1002804003744	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1002804003745	dimer interface [polypeptide binding]; other site
1002804003746	substrate binding site [chemical binding]; other site
1002804003747	metal binding sites [ion binding]; metal-binding site
1002804003748	adenylate kinase; Reviewed; Region: adk; PRK00279
1002804003749	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1002804003750	AMP-binding site [chemical binding]; other site
1002804003751	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1002804003752	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1002804003753	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1002804003754	dimer interface [polypeptide binding]; other site
1002804003755	anticodon binding site; other site
1002804003756	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1002804003757	homodimer interface [polypeptide binding]; other site
1002804003758	motif 1; other site
1002804003759	active site
1002804003760	motif 2; other site
1002804003761	GAD domain; Region: GAD; pfam02938
1002804003762	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1002804003763	active site
1002804003764	motif 3; other site
1002804003765	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1002804003766	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1002804003767	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804003768	active site
1002804003769	phosphorylation site [posttranslational modification]
1002804003770	intermolecular recognition site; other site
1002804003771	dimerization interface [polypeptide binding]; other site
1002804003772	potential frameshift: common BLAST hit: gi|298736308|ref|YP_003728834.1| NAD-dependent DNA ligase LigA
1002804003773	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1002804003774	nucleotide binding pocket [chemical binding]; other site
1002804003775	K-X-D-G motif; other site
1002804003776	catalytic site [active]
1002804003777	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1002804003778	nucleotide binding pocket [chemical binding]; other site
1002804003779	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1002804003780	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
1002804003781	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1002804003782	Dimer interface [polypeptide binding]; other site
1002804003783	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
1002804003784	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1002804003785	conjugal transfer protein TrbJ; Provisional; Region: PRK13874; cl02193
1002804003786	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1002804003787	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1002804003788	ligand binding site [chemical binding]; other site
1002804003789	translocation protein TolB; Provisional; Region: tolB; PRK04043
1002804003790	TolB amino-terminal domain; Region: TolB_N; pfam04052
1002804003791	Gram-negative bacterial tonB protein; Region: TonB; cl10048
1002804003792	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1002804003793	TolR protein; Region: tolR; TIGR02801
1002804003794	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
1002804003795	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1002804003796	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1002804003797	gamma subunit interface [polypeptide binding]; other site
1002804003798	epsilon subunit interface [polypeptide binding]; other site
1002804003799	LBP interface [polypeptide binding]; other site
1002804003800	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1002804003801	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1002804003802	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1002804003803	alpha subunit interaction interface [polypeptide binding]; other site
1002804003804	Walker A motif; other site
1002804003805	ATP binding site [chemical binding]; other site
1002804003806	Walker B motif; other site
1002804003807	inhibitor binding site; inhibition site
1002804003808	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1002804003809	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1002804003810	core domain interface [polypeptide binding]; other site
1002804003811	delta subunit interface [polypeptide binding]; other site
1002804003812	epsilon subunit interface [polypeptide binding]; other site
1002804003813	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1002804003814	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1002804003815	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1002804003816	beta subunit interaction interface [polypeptide binding]; other site
1002804003817	Walker A motif; other site
1002804003818	ATP binding site [chemical binding]; other site
1002804003819	Walker B motif; other site
1002804003820	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1002804003821	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
1002804003822	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1002804003823	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
1002804003824	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
1002804003825	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1002804003826	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1002804003827	biotin--protein ligase; Provisional; Region: PRK08477
1002804003828	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1002804003829	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1002804003830	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1002804003831	putative active site [active]
1002804003832	substrate binding site [chemical binding]; other site
1002804003833	putative cosubstrate binding site; other site
1002804003834	catalytic site [active]
1002804003835	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1002804003836	substrate binding site [chemical binding]; other site
1002804003837	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
1002804003838	LPP20 lipoprotein; Region: LPP20; pfam02169
1002804003839	7-cyano-7-deazaguanine tRNA-ribosyltransferase; Provisional; Region: PRK13534
1002804003840	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1002804003841	active site
1002804003842	zinc binding site [ion binding]; other site
1002804003843	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1002804003844	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1002804003845	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
1002804003846	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1002804003847	nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482
1002804003848	active site
1002804003849	(T/H)XGH motif; other site
1002804003850	potential frameshift: common BLAST hit: gi|315453016|ref|YP_004073286.1| nickel responsive regulator
1002804003851	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1002804003852	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1002804003853	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1002804003854	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1002804003855	Lumazine binding domain; Region: Lum_binding; pfam00677
1002804003856	Lumazine binding domain; Region: Lum_binding; pfam00677
1002804003857	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1002804003858	active site
1002804003859	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1002804003860	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1002804003861	catalytic residue [active]
1002804003862	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1002804003863	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1002804003864	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1002804003865	Sporulation related domain; Region: SPOR; pfam05036
1002804003866	OstA-like protein; Region: OstA; pfam03968
1002804003867	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1002804003868	G1 box; other site
1002804003869	GTP/Mg2+ binding site [chemical binding]; other site
1002804003870	Switch I region; other site
1002804003871	G2 box; other site
1002804003872	G3 box; other site
1002804003873	Switch II region; other site
1002804003874	G4 box; other site
1002804003875	G5 box; other site
1002804003876	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1002804003877	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1002804003878	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1002804003879	Initiator Replication protein; Region: Rep_3; pfam01051
1002804003880	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1002804003881	potential frameshift: common BLAST hit: gi|109948094|ref|YP_665322.1| mosaic CUP0956/HP1116/jhp1044-like protein
1002804003882	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
1002804003883	Predicted methyltransferases [General function prediction only]; Region: COG0313
1002804003884	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1002804003885	putative SAM binding site [chemical binding]; other site
1002804003886	putative homodimer interface [polypeptide binding]; other site
1002804003887	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1002804003888	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
1002804003889	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1002804003890	potential frameshift: common BLAST hit: gi|291276804|ref|YP_003516576.1| tryptophan synthase subunit beta
1002804003891	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1002804003892	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804003893	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1002804003894	catalytic residue [active]
1002804003895	potential frameshift: common BLAST hit: gi|315453395|ref|YP_004073665.1| biosynthetic arginine decarboxylase
1002804003896	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1002804003897	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1002804003898	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1002804003899	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1002804003900	catalytic residue [active]
1002804003901	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804003902	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1002804003903	potential frameshift: common BLAST hit: gi|315453054|ref|YP_004073324.1| methyl-accepting chemotaxis transmembrane sensory protein
1002804003904	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804003905	putative CheW interface [polypeptide binding]; other site
1002804003906	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1002804003907	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1002804003908	N-terminal plug; other site
1002804003909	ligand-binding site [chemical binding]; other site
1002804003910	Lecithin retinol acyltransferase; Region: LRAT; pfam04970
1002804003911	Proline dehydrogenase; Region: Pro_dh; cl03282
1002804003912	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1002804003913	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1002804003914	Glutamate binding site [chemical binding]; other site
1002804003915	NAD binding site [chemical binding]; other site
1002804003916	catalytic residues [active]
1002804003917	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1002804003918	Na binding site [ion binding]; other site
1002804003919	primosome assembly protein PriA; Validated; Region: PRK05580
1002804003920	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1002804003921	ATP binding site [chemical binding]; other site
1002804003922	putative Mg++ binding site [ion binding]; other site
1002804003923	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1002804003924	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003925	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804003926	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1002804003927	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1002804003928	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1002804003929	NAD(P) binding site [chemical binding]; other site
1002804003930	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1002804003931	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1002804003932	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1002804003933	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1002804003934	inhibitor-cofactor binding pocket; inhibition site
1002804003935	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804003936	catalytic residue [active]
1002804003937	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1002804003938	putative trimer interface [polypeptide binding]; other site
1002804003939	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1002804003940	putative CoA binding site [chemical binding]; other site
1002804003941	putative trimer interface [polypeptide binding]; other site
1002804003942	putative active site [active]
1002804003943	putative substrate binding site [chemical binding]; other site
1002804003944	putative CoA binding site [chemical binding]; other site
1002804003945	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1002804003946	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1002804003947	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1002804003948	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1002804003949	active site
1002804003950	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
1002804003951	homodimer interface [polypeptide binding]; other site
1002804003952	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1002804003953	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1002804003954	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1002804003955	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1002804003956	Part of AAA domain; Region: AAA_19; pfam13245
1002804003957	Family description; Region: UvrD_C_2; pfam13538
1002804003958	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1002804003959	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804003960	Sel1-like repeats; Region: SEL1; smart00671
1002804003961	Sel1-like repeats; Region: SEL1; smart00671
1002804003962	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1002804003963	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1002804003964	shikimate kinase; Reviewed; Region: aroK; PRK00131
1002804003965	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1002804003966	ADP binding site [chemical binding]; other site
1002804003967	magnesium binding site [ion binding]; other site
1002804003968	putative shikimate binding site; other site
1002804003969	enolase; Provisional; Region: eno; PRK00077
1002804003970	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1002804003971	dimer interface [polypeptide binding]; other site
1002804003972	metal binding site [ion binding]; metal-binding site
1002804003973	substrate binding pocket [chemical binding]; other site
1002804003974	potential frameshift: common BLAST hit: gi|315452862|ref|YP_004073132.1| valyl-tRNA synthetase
1002804003975	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1002804003976	active site
1002804003977	HIGH motif; other site
1002804003978	nucleotide binding site [chemical binding]; other site
1002804003979	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1002804003980	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1002804003981	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1002804003982	active site
1002804003983	KMSKS motif; other site
1002804003984	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1002804003985	tRNA binding surface [nucleotide binding]; other site
1002804003986	anticodon binding site; other site
1002804003987	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1002804003988	signal recognition particle protein; Provisional; Region: PRK10867
1002804003989	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1002804003990	P loop; other site
1002804003991	GTP binding site [chemical binding]; other site
1002804003992	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1002804003993	LabA_like proteins; Region: LabA_like; cd06167
1002804003994	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1002804003995	putative metal binding site [ion binding]; other site
1002804003996	variable surface protein Vir30; Provisional; Region: PTZ00229
1002804003997	LysE type translocator; Region: LysE; cl00565
1002804003998	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1002804003999	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1002804004000	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804004001	FeS/SAM binding site; other site
1002804004002	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
1002804004003	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1002804004004	active site
1002804004005	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1002804004006	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1002804004007	catalytic residue [active]
1002804004008	potential frameshift: common BLAST hit: gi|315452742|ref|YP_004073012.1| acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
1002804004009	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
1002804004010	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1002804004011	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1002804004012	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1002804004013	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804004014	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804004015	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804004016	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1002804004017	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1002804004018	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
1002804004019	Protein of unknown function (DUF493); Region: DUF493; pfam04359
1002804004020	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1002804004021	active site
1002804004022	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1002804004023	Na2 binding site [ion binding]; other site
1002804004024	putative substrate binding site 1 [chemical binding]; other site
1002804004025	Na binding site 1 [ion binding]; other site
1002804004026	putative substrate binding site 2 [chemical binding]; other site
1002804004027	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1002804004028	Na2 binding site [ion binding]; other site
1002804004029	putative substrate binding site 1 [chemical binding]; other site
1002804004030	Na binding site 1 [ion binding]; other site
1002804004031	putative substrate binding site 2 [chemical binding]; other site
1002804004032	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cl00248
1002804004033	dimerization interface [polypeptide binding]; other site
1002804004034	substrate binding site [chemical binding]; other site
1002804004035	active site
1002804004036	calcium binding site [ion binding]; other site
1002804004037	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1002804004038	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
1002804004039	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1002804004040	NAD binding site [chemical binding]; other site
1002804004041	homodimer interface [polypeptide binding]; other site
1002804004042	active site
1002804004043	substrate binding site [chemical binding]; other site
1002804004044	short chain dehydrogenase; Validated; Region: PRK06182
1002804004045	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1002804004046	NADP binding site [chemical binding]; other site
1002804004047	active site
1002804004048	steroid binding site; other site
1002804004049	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1002804004050	dimer interface [polypeptide binding]; other site
1002804004051	putative radical transfer pathway; other site
1002804004052	diiron center [ion binding]; other site
1002804004053	tyrosyl radical; other site
1002804004054	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1002804004055	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804004056	S-adenosylmethionine binding site [chemical binding]; other site
1002804004057	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1002804004058	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1002804004059	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1002804004060	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1002804004061	dimerization interface 3.5A [polypeptide binding]; other site
1002804004062	active site
1002804004063	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1002804004064	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1002804004065	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1002804004066	RDD family; Region: RDD; pfam06271
1002804004067	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1002804004068	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1002804004069	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
1002804004070	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1002804004071	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1002804004072	oligomer interface [polypeptide binding]; other site
1002804004073	RNA binding site [nucleotide binding]; other site
1002804004074	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1002804004075	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1002804004076	oligomer interface [polypeptide binding]; other site
1002804004077	RNA binding site [nucleotide binding]; other site
1002804004078	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1002804004079	putative nucleic acid binding region [nucleotide binding]; other site
1002804004080	G-X-X-G motif; other site
1002804004081	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
1002804004082	RNA binding site [nucleotide binding]; other site
1002804004083	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
1002804004084	potential frameshift: common BLAST hit: gi|315453534|ref|YP_004073804.1| putative riboflavin kinase /FMN adenylyltransferase
1002804004085	Riboflavin kinase; Region: Flavokinase; smart00904
1002804004086	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1002804004087	active site
1002804004088	Riboflavin kinase; Region: Flavokinase; smart00904
1002804004089	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1002804004090	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1002804004091	RNA binding surface [nucleotide binding]; other site
1002804004092	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804004093	S-adenosylmethionine binding site [chemical binding]; other site
1002804004094	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
1002804004095	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1002804004096	RuvA N terminal domain; Region: RuvA_N; pfam01330
1002804004097	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1002804004098	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1002804004099	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1002804004100	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1002804004101	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1002804004102	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1002804004103	active site
1002804004104	HIGH motif; other site
1002804004105	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1002804004106	KMSKS motif; other site
1002804004107	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1002804004108	tRNA binding surface [nucleotide binding]; other site
1002804004109	anticodon binding site; other site
1002804004110	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
1002804004111	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1002804004112	multimer interface [polypeptide binding]; other site
1002804004113	active site
1002804004114	catalytic triad [active]
1002804004115	dimer interface [polypeptide binding]; other site
1002804004116	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1002804004117	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
1002804004118	substrate binding site [chemical binding]; other site
1002804004119	catalytic residues [active]
1002804004120	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
1002804004121	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
1002804004122	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804004123	DNA methylase; Region: N6_N4_Mtase; pfam01555
1002804004124	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1002804004125	BNR repeat-like domain; Region: BNR_2; pfam13088
1002804004126	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1002804004127	active site
1002804004128	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1002804004129	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1002804004130	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1002804004131	flagellar motor switch protein; Validated; Region: PRK08433
1002804004132	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1002804004133	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1002804004134	minor groove reading motif; other site
1002804004135	helix-hairpin-helix signature motif; other site
1002804004136	substrate binding pocket [chemical binding]; other site
1002804004137	active site
1002804004138	FeoA domain; Region: FeoA; cl00838
1002804004139	Protein of unknown function; Region: DUF3971; pfam13116
1002804004140	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
1002804004141	YceG-like family; Region: YceG; pfam02618
1002804004142	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1002804004143	dimerization interface [polypeptide binding]; other site
1002804004144	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
1002804004145	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804004146	S-adenosylmethionine binding site [chemical binding]; other site
1002804004147	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1002804004148	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1002804004149	active site
1002804004150	HIGH motif; other site
1002804004151	KMSKS motif; other site
1002804004152	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1002804004153	tRNA binding surface [nucleotide binding]; other site
1002804004154	anticodon binding site; other site
1002804004155	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1002804004156	putative tRNA-binding site [nucleotide binding]; other site
1002804004157	dimer interface [polypeptide binding]; other site
1002804004158	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1002804004159	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1002804004160	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804004161	S-adenosylmethionine binding site [chemical binding]; other site
1002804004162	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1002804004163	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
1002804004164	putative ADP-binding pocket [chemical binding]; other site
1002804004165	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1002804004166	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1002804004167	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1002804004168	nucleotide binding region [chemical binding]; other site
1002804004169	ATP-binding site [chemical binding]; other site
1002804004170	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
1002804004171	SEC-C motif; Region: SEC-C; pfam02810
1002804004172	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1002804004173	FtsX-like permease family; Region: FtsX; pfam02687
1002804004174	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
1002804004175	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1002804004176	active site
1002804004177	catalytic site [active]
1002804004178	putative DNA binding site [nucleotide binding]; other site
1002804004179	GIY-YIG motif/motif A; other site
1002804004180	metal binding site [ion binding]; metal-binding site
1002804004181	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1002804004182	hypothetical protein; Provisional; Region: PRK05839
1002804004183	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1002804004184	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1002804004185	homodimer interface [polypeptide binding]; other site
1002804004186	catalytic residue [active]
1002804004187	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1002804004188	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1002804004189	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1002804004190	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1002804004191	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1002804004192	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804004193	Walker A/P-loop; other site
1002804004194	ATP binding site [chemical binding]; other site
1002804004195	Q-loop/lid; other site
1002804004196	ABC transporter signature motif; other site
1002804004197	Walker B; other site
1002804004198	D-loop; other site
1002804004199	H-loop/switch region; other site
1002804004200	Smr domain; Region: Smr; pfam01713
1002804004201	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1002804004202	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1002804004203	Ligand Binding Site [chemical binding]; other site
1002804004204	adenylosuccinate lyase; Provisional; Region: PRK08470
1002804004205	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1002804004206	tetramer interface [polypeptide binding]; other site
1002804004207	active site
1002804004208	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1002804004209	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
1002804004210	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
1002804004211	TPP-binding site [chemical binding]; other site
1002804004212	putative dimer interface [polypeptide binding]; other site
1002804004213	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
1002804004214	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1002804004215	dimer interface [polypeptide binding]; other site
1002804004216	PYR/PP interface [polypeptide binding]; other site
1002804004217	TPP binding site [chemical binding]; other site
1002804004218	substrate binding site [chemical binding]; other site
1002804004219	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1002804004220	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
1002804004221	4Fe-4S binding domain; Region: Fer4; pfam00037
1002804004222	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
1002804004223	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
1002804004224	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1002804004225	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1002804004226	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1002804004227	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1002804004228	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1002804004229	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1002804004230	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1002804004231	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1002804004232	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1002804004233	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1002804004234	catalytic residues [active]
1002804004235	hypothetical protein; Reviewed; Region: PRK12497
1002804004236	homoserine dehydrogenase; Provisional; Region: PRK06349
1002804004237	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1002804004238	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1002804004239	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1002804004240	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1002804004241	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1002804004242	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1002804004243	active site
1002804004244	phosphorylation site [posttranslational modification]
1002804004245	intermolecular recognition site; other site
1002804004246	dimerization interface [polypeptide binding]; other site
1002804004247	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1002804004248	DNA binding site [nucleotide binding]
1002804004249	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1002804004250	HAMP domain; Region: HAMP; pfam00672
1002804004251	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1002804004252	dimer interface [polypeptide binding]; other site
1002804004253	phosphorylation site [posttranslational modification]
1002804004254	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1002804004255	ATP binding site [chemical binding]; other site
1002804004256	Mg2+ binding site [ion binding]; other site
1002804004257	G-X-G motif; other site
1002804004258	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804004259	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1002804004260	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804004261	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1002804004262	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804004263	Sel1 repeat; Region: Sel1; cl02723
1002804004264	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1002804004265	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1002804004266	binding surface
1002804004267	TPR motif; other site
1002804004268	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1002804004269	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1002804004270	putative substrate translocation pore; other site
1002804004271	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1002804004272	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1002804004273	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1002804004274	Walker A/P-loop; other site
1002804004275	ATP binding site [chemical binding]; other site
1002804004276	ABC transporter signature motif; other site
1002804004277	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1002804004278	Walker B; other site
1002804004279	D-loop; other site
1002804004280	ABC transporter; Region: ABC_tran_2; pfam12848
1002804004281	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1002804004282	potential frameshift: common BLAST hit: gi|315453166|ref|YP_004073436.1| Cytoplasmic membrane protein
1002804004283	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1002804004284	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1002804004285	active site
1002804004286	metal binding site [ion binding]; metal-binding site
1002804004287	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1002804004288	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804004289	DNA polymerase I; Provisional; Region: PRK05755
1002804004290	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1002804004291	active site
1002804004292	metal binding site 1 [ion binding]; metal-binding site
1002804004293	putative 5' ssDNA interaction site; other site
1002804004294	metal binding site 3; metal-binding site
1002804004295	metal binding site 2 [ion binding]; metal-binding site
1002804004296	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1002804004297	putative DNA binding site [nucleotide binding]; other site
1002804004298	putative metal binding site [ion binding]; other site
1002804004299	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1002804004300	active site
1002804004301	DNA binding site [nucleotide binding]
1002804004302	catalytic site [active]
1002804004303	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1002804004304	DDE superfamily endonuclease; Region: DDE_5; cl17874
1002804004305	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1002804004306	Aspartase; Region: Aspartase; cd01357
1002804004307	active sites [active]
1002804004308	tetramer interface [polypeptide binding]; other site
1002804004309	hypothetical protein; Provisional; Region: PRK10621
1002804004310	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1002804004311	Arginase family; Region: Arginase; cd09989
1002804004312	active site
1002804004313	Mn binding site [ion binding]; other site
1002804004314	oligomer interface [polypeptide binding]; other site
1002804004315	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1002804004316	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1002804004317	NAD binding site [chemical binding]; other site
1002804004318	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
1002804004319	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1002804004320	crystallin beta/gamma motif-containing protein; Region: PHA00657
1002804004321	crystallin beta/gamma motif-containing protein; Region: PHA00657
1002804004322	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804004323	DNA methylase; Region: N6_N4_Mtase; pfam01555
1002804004324	potential frameshift: common BLAST hit: gi|315453449|ref|YP_004073719.1| transposase OrfB
1002804004325	Probable transposase; Region: OrfB_IS605; pfam01385
1002804004326	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1002804004327	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1002804004328	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1002804004329	Cupin domain; Region: Cupin_2; cl17218
1002804004330	Cupin domain; Region: Cupin_2; cl17218
1002804004331	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1002804004332	putative CoA binding site [chemical binding]; other site
1002804004333	putative trimer interface [polypeptide binding]; other site
1002804004334	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1002804004335	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1002804004336	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1002804004337	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1002804004338	putative CoA binding site [chemical binding]; other site
1002804004339	putative trimer interface [polypeptide binding]; other site
1002804004340	Cupin domain; Region: Cupin_2; cl17218
1002804004341	potential frameshift: common BLAST hit: gi|218563152|ref|YP_002344932.1| putative transcriptional regulator
1002804004342	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1002804004343	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1002804004344	DNA binding residues [nucleotide binding]
1002804004345	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1002804004346	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1002804004347	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
1002804004348	Strictosidine synthase; Region: Str_synth; pfam03088
1002804004349	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
1002804004350	active site 1 [active]
1002804004351	dimer interface [polypeptide binding]; other site
1002804004352	hexamer interface [polypeptide binding]; other site
1002804004353	active site 2 [active]
1002804004354	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1002804004355	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1002804004356	P-loop; other site
1002804004357	Magnesium ion binding site [ion binding]; other site
1002804004358	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1002804004359	Initiator Replication protein; Region: Rep_3; cl17676
1002804004360	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1002804004361	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1002804004362	active site
1002804004363	hypothetical protein; Provisional; Region: PRK11281
1002804004364	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1002804004365	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1002804004366	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1002804004367	Walker A motif; other site
1002804004368	hexamer interface [polypeptide binding]; other site
1002804004369	ATP binding site [chemical binding]; other site
1002804004370	Walker B motif; other site
1002804004371	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
1002804004372	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1002804004373	Walker A motif; other site
1002804004374	ATP binding site [chemical binding]; other site
1002804004375	Walker B motif; other site
1002804004376	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1002804004377	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1002804004378	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1002804004379	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1002804004380	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1002804004381	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1002804004382	nucleotide binding region [chemical binding]; other site
1002804004383	ATP-binding site [chemical binding]; other site
1002804004384	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
1002804004385	TOPRIM_TopoIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IA family of DNA topoisomerases (TopoIA). This subgroup contains proteins similar to the Type I DNA topoisomerases: E. coli...; Region: TOPRIM_TopoIA; cd01028
1002804004386	active site
1002804004387	interdomain interaction site; other site
1002804004388	putative metal-binding site [ion binding]; other site
1002804004389	nucleotide binding site [chemical binding]; other site
1002804004390	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1002804004391	domain I; other site
1002804004392	DNA binding groove [nucleotide binding]
1002804004393	phosphate binding site [ion binding]; other site
1002804004394	domain II; other site
1002804004395	domain III; other site
1002804004396	nucleotide binding site [chemical binding]; other site
1002804004397	catalytic site [active]
1002804004398	domain IV; other site
1002804004399	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1002804004400	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1002804004401	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1002804004402	Toprim-like; Region: Toprim_2; pfam13155
1002804004403	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
1002804004404	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
1002804004405	Endonuclease I; Region: Endonuclease_1; pfam04231
1002804004406	potential frameshift: common BLAST hit: gi|308185145|ref|YP_003929278.1| integrase/recombinase (xerD)
1002804004407	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1002804004408	DNA binding site [nucleotide binding]
1002804004409	active site
1002804004410	Int/Topo IB signature motif; other site
1002804004411	catalytic residues [active]
1002804004412	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1002804004413	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
1002804004414	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804004415	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1002804004416	Protein of unknown function DUF262; Region: DUF262; pfam03235
1002804004417	Protein of unknown function (DUF1115); Region: DUF1115; pfam06544
1002804004418	ATP-dependent protease Clp, ATPase subunit [Posttranslational modification, protein turnover, chaperones]; Region: ClpX; COG1219
1002804004419	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804004420	Walker A motif; other site
1002804004421	ATP binding site [chemical binding]; other site
1002804004422	Walker B motif; other site
1002804004423	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1002804004424	MerR family regulatory protein; Region: MerR; pfam00376
1002804004425	DNA binding residues [nucleotide binding]
1002804004426	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
1002804004427	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1002804004428	catalytic residues [active]
1002804004429	Probable transposase; Region: OrfB_IS605; pfam01385
1002804004430	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1002804004431	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1002804004432	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
1002804004433	Phage protein D [General function prediction only]; Region: COG3500
1002804004434	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1002804004435	Phage Tail Protein X; Region: Phage_tail_X; cl02088
1002804004436	potential frameshift: common BLAST hit: gi|225630450|ref|YP_002727241.1| tail tape measure protein
1002804004437	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1002804004438	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1002804004439	Phage tail tube protein FII; Region: Phage_tube; cl01390
1002804004440	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
1002804004441	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1002804004442	amidase catalytic site [active]
1002804004443	Zn binding residues [ion binding]; other site
1002804004444	substrate binding site [chemical binding]; other site
1002804004445	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
1002804004446	Baseplate J-like protein; Region: Baseplate_J; cl01294
1002804004447	Baseplate J-like protein; Region: Baseplate_J; pfam04865
1002804004448	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1002804004449	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
1002804004450	Ependymin; Region: Ependymin; cl02428
1002804004451	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1002804004452	Phage capsid family; Region: Phage_capsid; pfam05065
1002804004453	potential frameshift: common BLAST hit: gi|57237231|ref|YP_178243.1| DNA adenine methylase
1002804004454	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
1002804004455	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1002804004456	DNA primase, catalytic core; Region: dnaG; TIGR01391
1002804004457	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1002804004458	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1002804004459	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1002804004460	active site
1002804004461	metal binding site [ion binding]; metal-binding site
1002804004462	interdomain interaction site; other site
1002804004463	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1002804004464	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1002804004465	Phage portal protein, lambda family; Region: Phage_portal_2; pfam05136
1002804004466	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1002804004467	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
1002804004468	Phage DNA packaging protein Nu1; Region: Phage_Nu1; cl01720
1002804004469	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1002804004470	Predicted transcriptional regulator [Transcription]; Region: COG2932
1002804004471	Catalytic site [active]
1002804004472	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
1002804004473	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1002804004474	Walker A motif; other site
1002804004475	ATP binding site [chemical binding]; other site
1002804004476	Walker B motif; other site
1002804004477	YcfA-like protein; Region: YcfA; cl00752
1002804004478	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
1002804004479	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1002804004480	active site
1002804004481	catalytic residues [active]
1002804004482	DNA binding site [nucleotide binding]
1002804004483	Int/Topo IB signature motif; other site
1002804004484	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
1002804004485	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1002804004486	Walker A motif; other site
1002804004487	ATP binding site [chemical binding]; other site
1002804004488	Walker B motif; other site
1002804004489	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1002804004490	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
1002804004491	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1002804004492	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1002804004493	Sel1-like repeats; Region: SEL1; smart00671
1002804004494	Protein of unknown function (DUF511); Region: DUF511; cl01114
1002804004495	Protein of unknown function (DUF511); Region: DUF511; cl01114
1002804004496	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1002804004497	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1002804004498	Dynamin family; Region: Dynamin_N; pfam00350
1002804004499	G1 box; other site
1002804004500	GTP/Mg2+ binding site [chemical binding]; other site
1002804004501	G2 box; other site
1002804004502	Switch I region; other site
1002804004503	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1002804004504	G3 box; other site
1002804004505	Switch II region; other site
1002804004506	Protein of unknown function, DUF417; Region: DUF417; cl01162
1002804004507	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1002804004508	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
1002804004509	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1002804004510	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1002804004511	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1002804004512	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1002804004513	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1002804004514	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1002804004515	GTP binding site; other site
1002804004516	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1002804004517	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804004518	FeS/SAM binding site; other site
1002804004519	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1002804004520	hypothetical protein; Provisional; Region: PRK08444
1002804004521	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804004522	FeS/SAM binding site; other site
1002804004523	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1002804004524	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1002804004525	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1002804004526	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1002804004527	Surface antigen; Region: Bac_surface_Ag; pfam01103
1002804004528	hypothetical protein; Provisional; Region: PRK08445
1002804004529	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1002804004530	FeS/SAM binding site; other site
1002804004531	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1002804004532	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1002804004533	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1002804004534	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1002804004535	GatB domain; Region: GatB_Yqey; smart00845
1002804004536	Hemerythrin family; Region: Hemerythrin-like; cl15774
1002804004537	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
1002804004538	metal-binding heat shock protein; Provisional; Region: PRK00016
1002804004539	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1002804004540	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1002804004541	Ligand Binding Site [chemical binding]; other site
1002804004542	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1002804004543	DpnII restriction endonuclease; Region: DpnII; pfam04556
1002804004544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1002804004545	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1002804004546	DNA methylase; Region: N6_N4_Mtase; cl17433
1002804004547	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
1002804004548	ATP cone domain; Region: ATP-cone; pfam03477
1002804004549	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1002804004550	active site
1002804004551	dimer interface [polypeptide binding]; other site
1002804004552	catalytic residues [active]
1002804004553	effector binding site; other site
1002804004554	R2 peptide binding site; other site
1002804004555	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1002804004556	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1002804004557	G1 box; other site
1002804004558	putative GEF interaction site [polypeptide binding]; other site
1002804004559	GTP/Mg2+ binding site [chemical binding]; other site
1002804004560	Switch I region; other site
1002804004561	G2 box; other site
1002804004562	G3 box; other site
1002804004563	Switch II region; other site
1002804004564	G4 box; other site
1002804004565	G5 box; other site
1002804004566	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1002804004567	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1002804004568	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1002804004569	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1002804004570	active site
1002804004571	PHP Thumb interface [polypeptide binding]; other site
1002804004572	metal binding site [ion binding]; metal-binding site
1002804004573	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1002804004574	generic binding surface II; other site
1002804004575	generic binding surface I; other site
1002804004576	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1002804004577	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1002804004578	RNA binding surface [nucleotide binding]; other site
1002804004579	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1002804004580	active site
1002804004581	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1002804004582	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1002804004583	phosphate binding site [ion binding]; other site
1002804004584	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1002804004585	Sulfatase; Region: Sulfatase; pfam00884
1002804004586	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1002804004587	dimer interface [polypeptide binding]; other site
1002804004588	active site
1002804004589	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1002804004590	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
1002804004591	putative ribose interaction site [chemical binding]; other site
1002804004592	putative ADP binding site [chemical binding]; other site
1002804004593	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1002804004594	active site
1002804004595	HIGH motif; other site
1002804004596	nucleotide binding site [chemical binding]; other site
1002804004597	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1002804004598	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
1002804004599	NAD(P) binding site [chemical binding]; other site
1002804004600	active site
1002804004601	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1002804004602	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1002804004603	active site
1002804004604	motif I; other site
1002804004605	motif II; other site
1002804004606	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1002804004607	Type III pantothenate kinase; Region: Pan_kinase; cl17198
1002804004608	PQQ-like domain; Region: PQQ_2; pfam13360
1002804004609	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1002804004610	trimer interface [polypeptide binding]; other site
1002804004611	active site
1002804004612	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1002804004613	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1002804004614	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1002804004615	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1002804004616	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1002804004617	phosphodiesterase; Provisional; Region: PRK12704
1002804004618	KH domain; Region: KH_1; pfam00013
1002804004619	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1002804004620	Zn2+ binding site [ion binding]; other site
1002804004621	Mg2+ binding site [ion binding]; other site
1002804004622	potential frameshift: common BLAST hit: gi|315453062|ref|YP_004073332.1| methyl-accepting chemotaxis protein TlpB
1002804004623	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4564
1002804004624	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
1002804004625	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1002804004626	dimerization interface [polypeptide binding]; other site
1002804004627	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1002804004628	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1002804004629	dimer interface [polypeptide binding]; other site
1002804004630	putative CheW interface [polypeptide binding]; other site
1002804004631	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
1002804004632	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1002804004633	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1002804004634	active site
1002804004635	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1002804004636	substrate binding site [chemical binding]; other site
1002804004637	catalytic residues [active]
1002804004638	dimer interface [polypeptide binding]; other site
1002804004639	Chorismate mutase type II; Region: CM_2; cl00693
1002804004640	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
1002804004641	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1002804004642	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
1002804004643	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1002804004644	TPP-binding site [chemical binding]; other site
1002804004645	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
1002804004646	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1002804004647	dimer interface [polypeptide binding]; other site
1002804004648	PYR/PP interface [polypeptide binding]; other site
1002804004649	TPP binding site [chemical binding]; other site
1002804004650	substrate binding site [chemical binding]; other site
1002804004651	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1002804004652	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
1002804004653	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1002804004654	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1002804004655	potential frameshift: common BLAST hit: gi|315453240|ref|YP_004073510.1| NADH-ubiquinone oxidoreductase
1002804004656	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1002804004657	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1002804004658	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1002804004659	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1002804004660	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1002804004661	proton-translocating NADH-quinone oxidoreductase, chain L; Region: NDH_I_L; TIGR01974
1002804004662	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1002804004663	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1002804004664	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1002804004665	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1002804004666	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1002804004667	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1002804004668	4Fe-4S binding domain; Region: Fer4; cl02805
1002804004669	4Fe-4S binding domain; Region: Fer4; pfam00037
1002804004670	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1002804004671	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1002804004672	NADH dehydrogenase subunit G; Validated; Region: PRK08493
1002804004673	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1002804004674	catalytic loop [active]
1002804004675	iron binding site [ion binding]; other site
1002804004676	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1002804004677	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1002804004678	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1002804004679	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
1002804004680	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
1002804004681	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1002804004682	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1002804004683	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535