-- dump date 20140619_104829 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 71421000001 SEQ_END SEQ_END NC_000907.1 1830138 1830138 DR NC_000907.1; contig end 1830138..1830138 Haemophilus influenzae Rd KW20 NP_438174.1 CDS gapdH NC_000907.1 2 1021 D catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 2..1021 Haemophilus influenzae Rd KW20 950899 NP_438175.1 CDS HI0002 NC_000907.1 1190 3013 D similar to GB:AE000782; long chain fatty acid CoA ligase 1190..3013 Haemophilus influenzae Rd KW20 950897 NP_438176.1 CDS HI0003 NC_000907.1 3050 3838 R similar to GB:L10328 SP:P09997 PID:290545 PID:41648 GB:U00096; haloacid dehalogenase-like protein complement(3050..3838) Haemophilus influenzae Rd KW20 950898 NP_438177.1 CDS HI0004 NC_000907.1 3854 4318 R similar to GB:U00096 SP:P77385 PID:1778578 PID:1786880; metalloprotease complement(3854..4318) Haemophilus influenzae Rd KW20 950900 NP_438178.1 CDS fdhD NC_000907.1 4579 5391 R involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein complement(4579..5391) Haemophilus influenzae Rd KW20 950902 NP_438180.1 CDS fdxH NC_000907.1 8750 9688 D similar to SP:P24184 GB:U00096 PID:1742408 PID:1742418 PID:1787749; formate dehydrogenase subunit beta 8750..9688 Haemophilus influenzae Rd KW20 950904 NP_438181.1 CDS fdxI NC_000907.1 9681 10397 D similar to GB:L19201 SP:P32174 PID:304996 GB:U00096 PID:1790325; formate dehydrogenase subunit gamma 9681..10397 Haemophilus influenzae Rd KW20 950906 NP_438182.1 CDS fdhE NC_000907.1 10467 11375 D required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 10467..11375 Haemophilus influenzae Rd KW20 950905 NP_438183.1 CDS rimI NC_000907.1 11414 11854 R alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase complement(11414..11854) Haemophilus influenzae Rd KW20 950907 NP_438184.1 CDS holD NC_000907.1 11857 12261 R with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi complement(11857..12261) Haemophilus influenzae Rd KW20 950908 NP_438185.1 CDS rsmC NC_000907.1 12367 13359 D 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 12367..13359 Haemophilus influenzae Rd KW20 950903 NP_438186.1 CDS era NC_000907.1 13423 14331 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(13423..14331) Haemophilus influenzae Rd KW20 950911 NP_438187.1 CDS rnc NC_000907.1 14328 15011 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(14328..15011) Haemophilus influenzae Rd KW20 950910 NP_438188.1 CDS lepB NC_000907.1 15013 16062 R similar to GB:K00426 SP:P00803 PID:146600 PID:987643 GB:U00096; signal peptidase I complement(15013..16062) Haemophilus influenzae Rd KW20 950912 NP_438189.1 CDS lepA NC_000907.1 16071 17867 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(16071..17867) Haemophilus influenzae Rd KW20 950909 NP_438190.1 CDS HI0017 NC_000907.1 18035 18418 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(18035..18418) Haemophilus influenzae Rd KW20 950913 NP_438191.1 CDS ung NC_000907.1 18676 19335 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 18676..19335 Haemophilus influenzae Rd KW20 950914 NP_438192.1 CDS HI0019 NC_000907.1 19405 20829 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(19405..20829) Haemophilus influenzae Rd KW20 950916 NP_438193.1 CDS HI0020 NC_000907.1 21248 22687 R similar to GB:U00096 SP:P75763 PID:1786986; hypothetical protein complement(21248..22687) Haemophilus influenzae Rd KW20 950917 NP_438194.1 CDS citG NC_000907.1 22689 23939 R similar to GB:U00096 SP:P77231 PID:1778530 PID:1786830; CitG protein complement(22689..23939) Haemophilus influenzae Rd KW20 950919 NP_438195.1 CDS citF NC_000907.1 24267 25769 R similar to GB:U00096 SP:P75726 PID:1778532 PID:1786832; citrate lyase subunit alpha complement(24267..25769) Haemophilus influenzae Rd KW20 950920 NP_438196.2 CDS citE NC_000907.1 25784 26641 R similar to GB:U00096 SP:P77770 PID:1778533 PID:1786833; citrate lyase subunit beta complement(25784..26641) Haemophilus influenzae Rd KW20 950915 NP_438197.1 CDS citD NC_000907.1 26656 26943 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(26656..26943) Haemophilus influenzae Rd KW20 950921 NP_438198.1 CDS citC NC_000907.1 26981 27988 R similar to SP:P77390; citrate lyase ligase complement(26981..27988) Haemophilus influenzae Rd KW20 950918 NP_438199.1 CDS lipA NC_000907.1 28239 29201 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(28239..29201) Haemophilus influenzae Rd KW20 950923 NP_438200.1 CDS lipB NC_000907.1 29255 29893 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(29255..29893) Haemophilus influenzae Rd KW20 950925 NP_438201.1 CDS HI0028 NC_000907.1 29895 30173 R similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548; hypothetical protein complement(29895..30173) Haemophilus influenzae Rd KW20 950924 NP_438202.1 CDS dacA NC_000907.1 30229 31410 R similar to SP:P04287 PID:146620 PID:147661 PID:41212 GB:U00096; penicillin-binding protein 5 complement(30229..31410) Haemophilus influenzae Rd KW20 950922 NP_438203.1 CDS HI0030 NC_000907.1 31426 32289 R similar to GB:M18276 SP:P10100 PID:147660 GB:U00096 PID:1651260; lipoprotein complement(31426..32289) Haemophilus influenzae Rd KW20 950926 NP_438204.1 CDS rodA NC_000907.1 32341 33456 R similar to GB:M22857 SP:P15035 PID:147695 GB:U00096 PID:1651261; rod shape-determining protein complement(32341..33456) Haemophilus influenzae Rd KW20 950927 NP_438205.1 CDS pbp2 NC_000907.1 33446 35401 R similar to SP:P08150 GB:X04516 PID:147694 PID:42316 GB:U00096; penicillin-binding protein 2 complement(33446..35401) Haemophilus influenzae Rd KW20 950929 NP_438206.1 CDS HI0033 NC_000907.1 35422 35889 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(35422..35889) Haemophilus influenzae Rd KW20 950930 NP_438207.1 CDS HI0034 NC_000907.1 35943 36251 R similar to SP:P05848 GB:X04516 PID:42314 GB:U00096 PID:1778554; hypothetical protein complement(35943..36251) Haemophilus influenzae Rd KW20 950928 NP_438208.1 CDS HI0035 NC_000907.1 36376 38031 R similar to GB:L10328 SP:P29211 GB:M94104 PID:290534 PID:147371; hypothetical protein complement(36376..38031) Haemophilus influenzae Rd KW20 950933 NP_438209.1 CDS HI0036 NC_000907.1 38237 40015 D similar to SP:Q50614 PID:1483552; ABC transporter ATP-binding protein 38237..40015 Haemophilus influenzae Rd KW20 950931 NP_438210.2 CDS mreB NC_000907.1 40145 41200 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 40145..41200 Haemophilus influenzae Rd KW20 950934 NP_438211.1 CDS mreC NC_000907.1 41280 42335 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 41280..42335 Haemophilus influenzae Rd KW20 950932 NP_438212.1 CDS mreD NC_000907.1 42335 42823 D similar to GB:M31792 SP:P16927 PID:146819 PID:606189 GB:U00096; rod shape-determining protein MreD 42335..42823 Haemophilus influenzae Rd KW20 950936 NP_438213.1 CDS HI0040 NC_000907.1 42874 43650 R similar to PID:1944176; hypothetical protein complement(42874..43650) Haemophilus influenzae Rd KW20 950937 NP_438214.1 CDS xthA NC_000907.1 43660 44463 R removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III complement(43660..44463) Haemophilus influenzae Rd KW20 950938 NP_438215.1 CDS HI0042 NC_000907.1 44511 45185 R similar to SP:P39219 GB:U00096 PID:1786244; pseudouridine synthase-like protein complement(44511..45185) Haemophilus influenzae Rd KW20 950939 NP_438216.1 CDS HI0043 NC_000907.1 45185 46249 R similar to SP:P45525 GB:U00096 PID:1787582; hypothetical protein complement(45185..46249) Haemophilus influenzae Rd KW20 950940 NP_438217.1 CDS HI0044 NC_000907.1 46309 46971 R similar to SP:P06967 GB:X00547 PID:41284 GB:U00096 PID:1787205; hypothetical protein complement(46309..46971) Haemophilus influenzae Rd KW20 950935 NP_438218.1 CDS HI0045 NC_000907.1 47298 47852 R similar to GB:U14003 SP:P39187 PID:471102 PID:537057 GB:U00096; hypothetical protein complement(47298..47852) Haemophilus influenzae Rd KW20 950943 NP_438219.2 CDS phnA NC_000907.1 47955 48281 D similar to SP:P16680 GB:U14003 PID:147194 PID:536952 GB:U00096; alkylphosphonate uptake protein 47955..48281 Haemophilus influenzae Rd KW20 950944 NP_438220.1 CDS eda NC_000907.1 48334 48972 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(48334..48972) Haemophilus influenzae Rd KW20 950945 NP_438221.1 CDS HI0048 NC_000907.1 48991 49848 R Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase complement(48991..49848) Haemophilus influenzae Rd KW20 950942 NP_438222.1 CDS kdgK NC_000907.1 49848 50792 R similar to GB:X75047 SP:P45416 PID:495249; 2-dehydro-3-deoxygluconokinase complement(49848..50792) Haemophilus influenzae Rd KW20 950949 NP_438223.1 CDS HI0050m NC_000907.1 50812 52068 R integral membrane protein transporter complement(50812..52068) Haemophilus influenzae Rd KW20 950948 NP_438224.1 CDS HI0051 NC_000907.1 52092 52589 R similar to SP:P37674 PID:466715 GB:U00096 PID:1790002; hypothetical protein complement(52092..52589) Haemophilus influenzae Rd KW20 950946 NP_438225.1 CDS HI0052 NC_000907.1 52628 53614 R similar to SP:P37676 PID:466717 GB:U00096 PID:1790004; hypothetical protein complement(52628..53614) Haemophilus influenzae Rd KW20 950947 NP_438226.1 CDS HI0053 NC_000907.1 53641 54669 R similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126; zinc-type alcohol dehydrogenase complement(53641..54669) Haemophilus influenzae Rd KW20 950952 NP_438227.2 CDS uxuR NC_000907.1 54830 55579 D similar to GB:U14003 SP:P39161 PID:537165 PID:1160324 GB:U00096; uxu operon regulator 54830..55579 Haemophilus influenzae Rd KW20 950951 NP_438228.1 CDS uxuA NC_000907.1 55607 56791 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 55607..56791 Haemophilus influenzae Rd KW20 950950 NP_438229.1 CDS HI0056 NC_000907.1 56844 57557 R similar to PID:882725 GB:U00096 PID:1789197; hypothetical protein complement(56844..57557) Haemophilus influenzae Rd KW20 950954 NP_438230.1 CDS uvrC NC_000907.1 57655 59484 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(57655..59484) Haemophilus influenzae Rd KW20 950955 NP_438231.1 CDS kdsB NC_000907.1 59486 60250 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(59486..60250) Haemophilus influenzae Rd KW20 950957 NP_438232.1 CDS lpxK NC_000907.1 60321 61319 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(60321..61319) Haemophilus influenzae Rd KW20 950959 NP_438233.1 CDS msbA NC_000907.1 61392 63155 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease complement(61392..63155) Haemophilus influenzae Rd KW20 950953 NP_438234.1 CDS rec2 NC_000907.1 63196 65562 R similar to GB:L20805 PID:305386; recombination protein complement(63196..65562) Haemophilus influenzae Rd KW20 950960 NP_438235.1 CDS dksA NC_000907.1 65821 66258 D similar to GB:D26562 SP:P18274 GB:M34945 GB:M60726 PID:145751; dnaK suppressor protein 65821..66258 Haemophilus influenzae Rd KW20 950956 NP_438236.1 CDS pcnB NC_000907.1 66506 67864 D similar to SP:P13685 GB:D26562 GB:M20574 GB:S48039 PID:147117; polyA polymerase 66506..67864 Haemophilus influenzae Rd KW20 950961 NP_438237.1 CDS folK NC_000907.1 67873 68355 D ATP-binding protein; similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 67873..68355 Haemophilus influenzae Rd KW20 950962 NP_438238.1 CDS yjeE NC_000907.1 68431 68907 D forms homotrimers; magnesium-dependent; similar to SP:P31805 PID:304913 PID:537009 GB:U00096 PID:1790610; hypothetical protein 68431..68907 Haemophilus influenzae Rd KW20 950963 NP_438239.1 CDS HI0066 NC_000907.1 68915 70213 D similar to SP:P26365 GB:Z11831 PID:304914 PID:42068 PID:537010; N-acetylmuramoyl-L-alanine amidase 68915..70213 Haemophilus influenzae Rd KW20 950965 NP_438240.1 CDS mutL NC_000907.1 70214 72103 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 70214..72103 Haemophilus influenzae Rd KW20 950964 NP_438241.1 CDS miaA NC_000907.1 72111 73046 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 72111..73046 Haemophilus influenzae Rd KW20 950968 NP_438242.1 CDS glnE NC_000907.1 73052 75997 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 73052..75997 Haemophilus influenzae Rd KW20 950967 NP_438243.1 CDS recN NC_000907.1 76082 77758 R similar to SP:P05824 GB:Y00357 PID:42693 PID:1033112 GB:U00096; DNA repair protein complement(76082..77758) Haemophilus influenzae Rd KW20 950958 NP_438244.1 CDS ppnK NC_000907.1 77902 78687 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(77902..78687) Haemophilus influenzae Rd KW20 950969 NP_438245.2 CDS grpE NC_000907.1 78763 79455 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 78763..79455 Haemophilus influenzae Rd KW20 950971 NP_438246.1 CDS HI0073 NC_000907.1 79468 79812 R forms complexes with HI0074; nucleotidyltransferase complement(79468..79812) Haemophilus influenzae Rd KW20 950966 NP_438247.1 CDS HI0074 NC_000907.1 79805 80245 R forms homodimers and complexes with HI0073; nucleotidyltransferase complement(79805..80245) Haemophilus influenzae Rd KW20 950972 NP_438248.1 CDS nrdD NC_000907.1 80526 82649 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 80526..82649 Haemophilus influenzae Rd KW20 950970 NP_438249.1 CDS tesB NC_000907.1 82767 83627 D similar to GB:M63308 SP:P23911 PID:147932 GB:U00096 PID:1773136; acyl-CoA thioesterase II 82767..83627 Haemophilus influenzae Rd KW20 950974 NP_438250.1 CDS HI0077 NC_000907.1 83638 84504 D hypothetical protein 83638..84504 Haemophilus influenzae Rd KW20 950975 NP_438251.1 CDS cysS NC_000907.1 84580 85959 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(84580..85959) Haemophilus influenzae Rd KW20 950973 NP_438252.1 CDS ppiB NC_000907.1 86062 86571 D similar to GB:M55430 SP:P23869 GB:X59293 PID:145290 PID:41205; peptidyl-prolyl cis-trans isomerase B 86062..86571 Haemophilus influenzae Rd KW20 950978 NP_438253.1 CDS HI0080 NC_000907.1 86575 87006 D similar to GB:U00096 PID:2367279; hypothetical protein 86575..87006 Haemophilus influenzae Rd KW20 950976 NP_438254.1 CDS HI0081 NC_000907.1 87148 87936 D similar to GB:U14003 SP:P39408 PID:537218 GB:U00096 PID:1790838; hypothetical protein 87148..87936 Haemophilus influenzae Rd KW20 950980 NP_438255.1 CDS HI0082 NC_000907.1 88193 88459 D hypothetical protein 88193..88459 Haemophilus influenzae Rd KW20 950979 NP_438257.1 CDS trxM NC_000907.1 88739 89062 R similar to GB:J04475 SP:P12243 PID:142154; thioredoxin complement(88739..89062) Haemophilus influenzae Rd KW20 950983 NP_438258.1 CDS ldhA NC_000907.1 89182 90177 R Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes; D-lactate dehydrogenase complement(89182..90177) Haemophilus influenzae Rd KW20 950977 NP_438259.1 CDS metB NC_000907.1 90190 91335 R catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase complement(90190..91335) Haemophilus influenzae Rd KW20 950982 NP_438260.1 CDS thrC NC_000907.1 92148 93425 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(92148..93425) Haemophilus influenzae Rd KW20 950990 NP_438261.1 CDS thrB NC_000907.1 93468 94412 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(93468..94412) Haemophilus influenzae Rd KW20 950993 NP_438262.1 CDS thrA NC_000907.1 94425 96872 R multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I complement(94425..96872) Haemophilus influenzae Rd KW20 950991 NP_438263.1 CDS HI0090 NC_000907.1 97196 97909 D similar to PID:882480 SP:P52054 GB:U00096 PID:1789321; hypothetical protein 97196..97909 Haemophilus influenzae Rd KW20 950992 NP_438264.1 CDS HI0091 NC_000907.1 97949 99085 R similar to SP:P42100 PID:563934 PID:904179 GB:AL009126; hypothetical protein complement(97949..99085) Haemophilus influenzae Rd KW20 950989 NP_438265.1 CDS HI0092 NC_000907.1 99094 100353 R hypothetical protein complement(99094..100353) Haemophilus influenzae Rd KW20 950987 NP_438266.1 CDS HI0093 NC_000907.1 100475 101581 R similar to SP:P37047 GB:U00096 PID:1552740 PID:1786357; hypothetical protein complement(100475..101581) Haemophilus influenzae Rd KW20 950994 NP_438268.2 CDS HI0094 NC_000907.1 101783 102103 R hypothetical protein complement(101783..102103) Haemophilus influenzae Rd KW20 950995 NP_438269.1 CDS HI0095 NC_000907.1 102453 103208 R similar to PID:2104289; hypothetical protein complement(102453..103208) Haemophilus influenzae Rd KW20 950997 NP_438270.1 CDS HI0096 NC_000907.1 103542 104117 D hypothetical protein 103542..104117 Haemophilus influenzae Rd KW20 951000 NP_438271.2 CDS hitA NC_000907.1 104277 105274 D periplasmic ferric iron binding protein; contains a frameshift with respect to purified protein; similar to PID:2340838; iron-utilization periplasmic protein hFbpA join(104277..104318,104318..105274) Haemophilus influenzae Rd KW20 950998 NP_438272.2 CDS hitB NC_000907.1 105476 106912 D similar to GB:M33815 SP:P21409 PID:152861; iron(III) ABC transporter permease 105476..106912 Haemophilus influenzae Rd KW20 951001 NP_438273.1 CDS hitC NC_000907.1 106914 107969 D similar to PID:1098689; iron(III) ABC transporter ATP-binding protein 106914..107969 Haemophilus influenzae Rd KW20 951003 NP_438276.1 CDS dapE NC_000907.1 108685 109818 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(108685..109818) Haemophilus influenzae Rd KW20 950999 NP_438277.1 CDS HI0103 NC_000907.1 109846 110190 R similar to SP:P24178 GB:X57403 PID:41233 GB:U00096 PID:1788815; hypothetical protein complement(109846..110190) Haemophilus influenzae Rd KW20 951002 NP_438278.1 CDS htpG NC_000907.1 110269 112164 R molecular chaperone; heat shock protein 90 complement(110269..112164) Haemophilus influenzae Rd KW20 951006 NP_438279.2 CDS HI0105 NC_000907.1 112465 113220 D similar to GB:U00096 SP:P75743 PID:1786928; hypothetical protein 112465..113220 Haemophilus influenzae Rd KW20 951007 NP_438280.1 CDS ffh NC_000907.1 113277 114665 R similar to SP:P07019 PID:43142 GB:U00096 PID:1788963; Signal recognition particle protein complement(113277..114665) Haemophilus influenzae Rd KW20 951009 NP_438281.1 CDS HI0107 NC_000907.1 114997 116208 D similar to GB:U00096 PID:1788966; Mg2+/Co2+ transporter 114997..116208 Haemophilus influenzae Rd KW20 951005 NP_438282.1 CDS HI0108 NC_000907.1 116337 117230 D similar to GB:U14003 SP:P39402 PID:537207 GB:U00096 PID:1790826; hypothetical protein 116337..117230 Haemophilus influenzae Rd KW20 951010 NP_438283.1 CDS HI0109 NC_000907.1 117319 117660 R hypothetical protein complement(117319..117660) Haemophilus influenzae Rd KW20 951013 NP_438284.1 CDS serS NC_000907.1 117827 119116 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 117827..119116 Haemophilus influenzae Rd KW20 951014 NP_438285.1 CDS bphH NC_000907.1 119451 120080 D similar to GB:X76500 PID:520921; glutathione transferase 119451..120080 Haemophilus influenzae Rd KW20 951011 NP_438286.1 CDS HI0112 NC_000907.1 120092 120388 R hypothetical protein complement(120092..120388) Haemophilus influenzae Rd KW20 951016 NP_438287.1 CDS hemR NC_000907.1 120441 122675 D similar to SP:Q56989 PID:1407797; hemin receptor 120441..122675 Haemophilus influenzae Rd KW20 951015 NP_438289.1 CDS mltA NC_000907.1 132027 132959 D murein transglycosylase A 132027..132959 Haemophilus influenzae Rd KW20 951025 NP_438290.1 CDS HI0118 NC_000907.1 132944 133729 D similar to GB:D21145 PID:471103 PID:882707 GB:U00096 SP:Q46927; hypothetical protein 132944..133729 Haemophilus influenzae Rd KW20 951021 NP_438291.1 CDS znuA NC_000907.1 133907 134920 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter substrate-binding protein 133907..134920 Haemophilus influenzae Rd KW20 951027 NP_438292.1 CDS HI0120 NC_000907.1 134970 135476 R hypothetical protein complement(134970..135476) Haemophilus influenzae Rd KW20 951028 NP_438293.1 CDS HI0121 NC_000907.1 135589 136950 R similar to GB:U14003 SP:P37773 PID:537075 GB:U00096 PID:1790680; UDP-N-acetylmuramoylalanine-D-glutamate ligase-like protein complement(135589..136950) Haemophilus influenzae Rd KW20 951026 NP_438294.1 CDS metC NC_000907.1 137335 138525 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(137335..138525) Haemophilus influenzae Rd KW20 951030 NP_438295.1 CDS pgsA NC_000907.1 138800 139357 D similar to GB:M12299 SP:P06978 PID:473749 GB:U00096 PID:1736571; phosphatidylglycerophosphate synthase 138800..139357 Haemophilus influenzae Rd KW20 951031 NP_438296.1 CDS ppa NC_000907.1 139924 140454 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(139924..140454) Haemophilus influenzae Rd KW20 951032 NP_438297.1 CDS HI0125 NC_000907.1 140689 142005 D similar to SP:P32702 PID:396399 GB:U00096 PID:1790499; hypothetical protein 140689..142005 Haemophilus influenzae Rd KW20 951038 NP_438298.1 CDS fbpC NC_000907.1 142163 143149 R Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding protein complement(142163..143149) Haemophilus influenzae Rd KW20 951036 NP_438299.1 CDS afuB NC_000907.1 143193 145091 R ferric transport system permease-like protein complement(143193..145091) Haemophilus influenzae Rd KW20 951037 NP_438300.1 CDS afuA NC_000907.1 145395 146435 R AfuA; similar to PID:1469286 PID:1477455; ferric ABC transporter protein complement(145395..146435) Haemophilus influenzae Rd KW20 951040 NP_438301.1 CDS udk NC_000907.1 146601 147242 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 146601..147242 Haemophilus influenzae Rd KW20 951039 NP_438302.1 CDS dcd NC_000907.1 147251 147838 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 147251..147838 Haemophilus influenzae Rd KW20 951042 NP_438303.1 CDS HI0134 NC_000907.1 147842 149017 D hypothetical protein 147842..149017 Haemophilus influenzae Rd KW20 951034 NP_438304.1 CDS HI0135 NC_000907.1 149017 150207 D similar to GB:AE000511 PID:2314345; sugar efflux transporter 149017..150207 Haemophilus influenzae Rd KW20 951043 NP_438305.1 CDS engA NC_000907.1 150287 151801 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(150287..151801) Haemophilus influenzae Rd KW20 951041 NP_438306.1 CDS dnaQ NC_000907.1 152492 153262 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(152492..153262) Haemophilus influenzae Rd KW20 951047 NP_438307.1 CDS rnhA NC_000907.1 153323 153787 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 153323..153787 Haemophilus influenzae Rd KW20 951050 NP_438308.1 CDS ompP2 NC_000907.1 154039 155118 D similar to GB:J03359 SP:P20149; outer membrane protein P2 154039..155118 Haemophilus influenzae Rd KW20 951048 NP_438309.1 CDS nagA NC_000907.1 155307 156452 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(155307..156452) Haemophilus influenzae Rd KW20 951049 NP_438310.1 CDS nagB NC_000907.1 156725 157537 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(156725..157537) Haemophilus influenzae Rd KW20 951053 NP_438311.1 CDS nanA NC_000907.1 157823 158704 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(157823..158704) Haemophilus influenzae Rd KW20 951045 NP_438312.1 CDS HI0143 NC_000907.1 158715 159581 R similar to GB:M81878 SP:P26833 PID:144859; hypothetical protein complement(158715..159581) Haemophilus influenzae Rd KW20 951052 NP_438313.1 CDS HI0144 NC_000907.1 159574 160476 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(159574..160476) Haemophilus influenzae Rd KW20 951055 NP_438314.1 CDS HI0145 NC_000907.1 160522 161208 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(160522..161208) Haemophilus influenzae Rd KW20 951054 NP_438315.1 CDS HI0146 NC_000907.1 161558 162547 D similar to SP:P37676 PID:466717 GB:U00096 PID:1790004; hypothetical protein 161558..162547 Haemophilus influenzae Rd KW20 951056 NP_438316.1 CDS HI0147 NC_000907.1 162558 164459 D similar to SP:P37675 PID:466716 GB:U00096 PID:1790003; hypothetical protein 162558..164459 Haemophilus influenzae Rd KW20 951057 NP_438317.1 CDS HI0148 NC_000907.1 164623 165762 D similar to GB:U14003 SP:P39371 PID:537151 GB:U00096 PID:1790764; N-acetylneuraminic acid mutarotase 164623..165762 Haemophilus influenzae Rd KW20 951058 NP_438320.1 CDS hflC NC_000907.1 166400 167287 R similar to SP:P25661 GB:U00005 PID:436158 PID:537016 GB:U00096; hypothetical protein complement(166400..167287) Haemophilus influenzae Rd KW20 951060 NP_438321.1 CDS hflK NC_000907.1 167287 168519 R similar to SP:P25662 GB:U00005 PID:436157 PID:537015 GB:U00096; HflK protein complement(167287..168519) Haemophilus influenzae Rd KW20 951061 NP_438322.1 CDS HI0152 NC_000907.1 168629 169336 R hypothetical protein complement(168629..169336) Haemophilus influenzae Rd KW20 951063 NP_438324.1 CDS acpP NC_000907.1 170930 171160 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(170930..171160) Haemophilus influenzae Rd KW20 951065 NP_438325.1 CDS fabG NC_000907.1 171416 172144 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(171416..172144) Haemophilus influenzae Rd KW20 951066 NP_438326.1 CDS fabD NC_000907.1 172161 173099 R similar to GB:M87040 SP:P25715 GB:Z11565 PID:145887 PID:41364; acyl carrier protein S-malonyltransferase complement(172161..173099) Haemophilus influenzae Rd KW20 951062 NP_438327.1 CDS fabH NC_000907.1 173727 174677 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(173727..174677) Haemophilus influenzae Rd KW20 951067 NP_438328.1 CDS rpmF NC_000907.1 174863 175033 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(174863..175033) Haemophilus influenzae Rd KW20 951068 NP_438329.1 CDS HI0159 NC_000907.1 175056 175580 R similar to GB:M29698 SP:P14189 PID:146052 PID:147711 GB:U00096; hypothetical protein complement(175056..175580) Haemophilus influenzae Rd KW20 951069 NP_438330.1 CDS psd NC_000907.1 175737 176609 D catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 175737..176609 Haemophilus influenzae Rd KW20 951070 NP_438331.1 CDS gor NC_000907.1 176718 178088 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(176718..178088) Haemophilus influenzae Rd KW20 951071 NP_438332.1 CDS HI0162 NC_000907.1 178304 178903 R similar to GB:U00096 PID:1773118 PID:1786637; lipoprotein complement(178304..178903) Haemophilus influenzae Rd KW20 951072 NP_438333.1 CDS bolA NC_000907.1 178997 179308 D similar to PID:663269; transcriptional regulator 178997..179308 Haemophilus influenzae Rd KW20 951075 NP_438334.1 CDS HI0164 NC_000907.1 179599 180942 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 179599..180942 Haemophilus influenzae Rd KW20 951076 NP_438335.1 CDS nqrB NC_000907.1 180945 182180 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 180945..182180 Haemophilus influenzae Rd KW20 951078 NP_438336.1 CDS HI0167 NC_000907.1 182173 182907 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 182173..182907 Haemophilus influenzae Rd KW20 951074 NP_438337.1 CDS HI0168 NC_000907.1 182907 183533 D Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 182907..183533 Haemophilus influenzae Rd KW20 951073 NP_438338.1 CDS HI0170 NC_000907.1 183537 184133 D Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 183537..184133 Haemophilus influenzae Rd KW20 951077 NP_438339.1 CDS nqr6 NC_000907.1 184146 185381 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 184146..185381 Haemophilus influenzae Rd KW20 951079 NP_438340.1 CDS HI0172 NC_000907.1 185525 186565 D similar to SP:P33944 PID:405940 GB:U00096 PID:1788543; lipoprotein 185525..186565 Haemophilus influenzae Rd KW20 951081 NP_438341.1 CDS HI0173 NC_000907.1 186568 186828 D hypothetical protein 186568..186828 Haemophilus influenzae Rd KW20 951082 NP_438342.1 CDS mnmA NC_000907.1 186840 188096 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 186840..188096 Haemophilus influenzae Rd KW20 951080 NP_438343.1 CDS HI0175 NC_000907.1 188140 188874 R similar to SP:P33644 GB:M29364 PID:1236632 PID:147364 GB:U00096; hypothetical protein complement(188140..188874) Haemophilus influenzae Rd KW20 951085 NP_438344.1 CDS rluD NC_000907.1 188876 189850 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(188876..189850) Haemophilus influenzae Rd KW20 951084 NP_438345.1 CDS HI0177 NC_000907.1 189958 190746 D similar to PID:1107833; hypothetical protein 189958..190746 Haemophilus influenzae Rd KW20 951089 NP_438346.1 CDS HI0178 NC_000907.1 190826 191308 R hypothetical protein complement(190826..191308) Haemophilus influenzae Rd KW20 951088 NP_438347.1 CDS pflA NC_000907.1 191340 192080 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(191340..192080) Haemophilus influenzae Rd KW20 951086 NP_438348.1 CDS HI0180 NC_000907.1 192211 194529 R similar to GB:X08035 SP:P09373 PID:42370 GB:U00096 PID:1651427; formate acetyltransferase complement(192211..194529) Haemophilus influenzae Rd KW20 951083 NP_438349.1 CDS HI0181 NC_000907.1 194557 195411 R similar to SP:P21501 PID:147154 GB:U00096 PID:1651428 PID:1651435; formate transporter complement(194557..195411) Haemophilus influenzae Rd KW20 951090 NP_438350.2 CDS HI0182 NC_000907.1 195915 196829 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 195915..196829 Haemophilus influenzae Rd KW20 951092 NP_438351.1 CDS HI0183 NC_000907.1 197006 198451 D similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126; amino acid carrier protein 197006..198451 Haemophilus influenzae Rd KW20 951094 NP_438352.1 CDS HI0184 NC_000907.1 198638 199465 R similar to SP:P10768; esterase complement(198638..199465) Haemophilus influenzae Rd KW20 951093 NP_438353.1 CDS adhC NC_000907.1 199474 200610 R similar to SP:P25437 PID:887431 GB:U00096 PID:1786552 PID:2443392; alcohol dehydrogenase class III complement(199474..200610) Haemophilus influenzae Rd KW20 951091 NP_438354.1 CDS HI0186 NC_000907.1 200733 201140 D similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126; HTH-type transcriptional regulator 200733..201140 Haemophilus influenzae Rd KW20 951087 NP_438355.1 CDS tatA NC_000907.1 201358 201627 D Sec-independent protein secretion pathway component TatA 201358..201627 Haemophilus influenzae Rd KW20 951097 NP_438356.1 CDS tatB NC_000907.1 201591 202151 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 201591..202151 Haemophilus influenzae Rd KW20 951096 NP_438357.1 CDS HI0188 NC_000907.1 202161 202931 D similar to SP:P27857 GB:M87049 PID:148238 PID:148237 GB:U00096; Sec-independent protein translocase protein TatC 202161..202931 Haemophilus influenzae Rd KW20 951098 NP_438358.1 CDS gdhA NC_000907.1 203291 204640 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 203291..204640 Haemophilus influenzae Rd KW20 951095 NP_438359.1 CDS fur NC_000907.1 204748 205188 R similar to PID:1568605; ferric uptake regulation protein complement(204748..205188) Haemophilus influenzae Rd KW20 951099 NP_438360.1 CDS fldA NC_000907.1 205217 205741 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(205217..205741) Haemophilus influenzae Rd KW20 951101 NP_438361.2 CDS HI0193 NC_000907.1 205838 206620 R similar to GB:U00096 PID:1786902; esterase/lipase complement(205838..206620) Haemophilus influenzae Rd KW20 951100 NP_438362.1 CDS seqA NC_000907.1 206691 207284 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 206691..207284 Haemophilus influenzae Rd KW20 951105 NP_438363.1 CDS menE NC_000907.1 207287 208645 D similar to GB:L35031 SP:P37353 PID:520813 GB:U00096 PID:1788595; O-succinylbenzoic acid--CoA ligase 207287..208645 Haemophilus influenzae Rd KW20 951106 NP_438364.1 CDS HI0195.1 NC_000907.1 208672 212007 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 208672..212007 Haemophilus influenzae Rd KW20 951104 NP_438365.1 CDS aroC NC_000907.1 212017 213090 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 212017..213090 Haemophilus influenzae Rd KW20 951107 NP_438366.1 CDS mepA NC_000907.1 213175 214035 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 213175..214035 Haemophilus influenzae Rd KW20 951103 NP_438367.1 CDS HI0198 NC_000907.1 214053 214820 D similar to SP:P14008 PID:41996 GB:U00096 PID:1788667; hypothetical protein 214053..214820 Haemophilus influenzae Rd KW20 951110 NP_438368.1 CDS msbB NC_000907.1 214867 215823 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 214867..215823 Haemophilus influenzae Rd KW20 951108 NP_438369.1 CDS selD NC_000907.1 215881 216921 D catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 215881..216921 Haemophilus influenzae Rd KW20 951109 NP_438370.2 CDS rplS NC_000907.1 217030 217380 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(217030..217380) Haemophilus influenzae Rd KW20 951102 NP_438371.1 CDS trmD NC_000907.1 217417 218157 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(217417..218157) Haemophilus influenzae Rd KW20 951111 NP_438372.2 CDS rimM NC_000907.1 218195 218722 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(218195..218722) Haemophilus influenzae Rd KW20 951115 NP_438373.1 CDS rpsP NC_000907.1 218767 219015 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(218767..219015) Haemophilus influenzae Rd KW20 951113 NP_438374.1 CDS HI0205 NC_000907.1 219308 220081 D hypothetical protein 219308..220081 Haemophilus influenzae Rd KW20 951114 NP_438375.1 CDS HI0206 NC_000907.1 220104 221915 D similar to SP:P29240 PID:62772; NAD nucleotidase 220104..221915 Haemophilus influenzae Rd KW20 951116 NP_438376.1 CDS aroK NC_000907.1 222200 222742 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 222200..222742 Haemophilus influenzae Rd KW20 951112 NP_438377.1 CDS aroB NC_000907.1 222762 223850 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 222762..223850 Haemophilus influenzae Rd KW20 951118 NP_438378.1 CDS dam NC_000907.1 223852 224712 D similar to GB:J01600 SP:P00475 GB:V00272 GB:Z19601 PID:145706; DNA adenine methylase 223852..224712 Haemophilus influenzae Rd KW20 951117 NP_438379.1 CDS pgpB NC_000907.1 225814 226539 R similar to GB:M23628 SP:P18201 PID:450384 GB:U00096 PID:1742092; phosphatidylglycerophosphatase B complement(225814..226539) Haemophilus influenzae Rd KW20 951120 NP_438380.2 CDS ribA NC_000907.1 226608 227258 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 226608..227258 Haemophilus influenzae Rd KW20 951119 NP_438381.1 CDS HI0213 NC_000907.1 227577 229121 R similar to SP:P06202 GB:X05491 GB:X52093 PID:47802 PID:47808; oligopeptide transporter substrate-binding protein complement(227577..229121) Haemophilus influenzae Rd KW20 951122 NP_438383.2 CDS prlC NC_000907.1 229603 231642 D similar to SP:P27298 GB:M93984 PID:451277 PID:466635 GB:U00096; oligopeptidase A 229603..231642 Haemophilus influenzae Rd KW20 951121 NP_438384.1 CDS hsdS NC_000907.1 233477 234634 D similar to GB:X73984 PID:393411; type I restriction/modification specificity protein 233477..234634 Haemophilus influenzae Rd KW20 951125 NP_438385.1 CDS HI0217 NC_000907.1 234763 235293 D similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422; hypothetical protein 234763..235293 Haemophilus influenzae Rd KW20 951128 NP_438387.2 CDS HI0219 NC_000907.1 238674 239303 R similar to GB:S68137 SP:P46928 PID:469476; hypothetical protein complement(238674..239303) Haemophilus influenzae Rd KW20 951126 NP_438388.1 CDS HI0219a NC_000907.1 239516 240229 R two component signal transduction system protein complement(239516..240229) Haemophilus influenzae Rd KW20 951131 NP_438390.2 CDS HI0220.2 NC_000907.1 241428 242015 R hypothetical protein complement(241428..242015) Haemophilus influenzae Rd KW20 951123 NP_438391.1 CDS birA NC_000907.1 247910 248818 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(247910..248818) Haemophilus influenzae Rd KW20 951136 NP_438392.1 CDS guaB NC_000907.1 248948 250414 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 248948..250414 Haemophilus influenzae Rd KW20 951137 NP_438393.1 CDS HI0221.1 NC_000907.1 250524 251015 D similar to C-terminus of HI0221; inosine-5'-monophosphate dehydrogenase-like protein 250524..251015 Haemophilus influenzae Rd KW20 951134 NP_438394.1 CDS guaA NC_000907.1 251125 252696 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 251125..252696 Haemophilus influenzae Rd KW20 951140 NP_438395.1 CDS HI0223 NC_000907.1 252758 253660 R similar to SP:P27844; hypothetical protein complement(252758..253660) Haemophilus influenzae Rd KW20 951139 NP_438396.2 CDS HI0224 NC_000907.1 253772 254233 D similar to SP:P55658 PID:2182633; transcriptional regulator 253772..254233 Haemophilus influenzae Rd KW20 951138 NP_438397.1 CDS nhaA NC_000907.1 254272 255474 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(254272..255474) Haemophilus influenzae Rd KW20 951141 NP_438398.1 CDS brnQ NC_000907.1 255662 256972 D similar to SP:P37011 GB:U00096 PID:1657597 PID:1773085 PID:1786601; branched-chain amino acid ABC transporter 255662..256972 Haemophilus influenzae Rd KW20 951144 NP_438399.1 CDS HI0227 NC_000907.1 257080 257547 R similar to SP:P37673 PID:466714 GB:U00096 PID:1790001; hypothetical protein complement(257080..257547) Haemophilus influenzae Rd KW20 951142 NP_438401.1 CDS pnp NC_000907.1 258296 260425 D similar to GB:J02638 SP:P05055 GB:M14425 GB:X00761 PID:147749; polynucleotide phosphorylase/polyadenylase 258296..260425 Haemophilus influenzae Rd KW20 951143 NP_438402.1 CDS HI0230 NC_000907.1 260507 261451 D lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 260507..261451 Haemophilus influenzae Rd KW20 951148 NP_438403.1 CDS deaD NC_000907.1 261572 263413 D similar to SP:P23304 GB:M63288 GB:U03750 PID:432406 PID:606102; ATP-dependent RNA helicase 261572..263413 Haemophilus influenzae Rd KW20 951147 NP_438404.1 CDS HI0232 NC_000907.1 263591 264979 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 263591..264979 Haemophilus influenzae Rd KW20 951149 NP_438406.1 CDS HI0235 NC_000907.1 265624 265833 R similar to GB:L29458 SP:P36675 PID:473421; hypothetical protein complement(265624..265833) Haemophilus influenzae Rd KW20 951152 NP_438407.1 CDS HI0236 NC_000907.1 265901 266251 R similar to PID:1805555; arsenate reductase complement(265901..266251) Haemophilus influenzae Rd KW20 951153 NP_438409.1 CDS secF NC_000907.1 267493 268470 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(267493..268470) Haemophilus influenzae Rd KW20 951151 NP_438410.1 CDS secD NC_000907.1 268478 270328 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(268478..270328) Haemophilus influenzae Rd KW20 951150 NP_438411.1 CDS yajC NC_000907.1 270398 270691 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(270398..270691) Haemophilus influenzae Rd KW20 949367 NP_438412.1 CDS HI0242 NC_000907.1 270799 271020 R similar to GB:L77117 SP:Q58397 PID:1591652; hypothetical protein complement(270799..271020) Haemophilus influenzae Rd KW20 949384 NP_438413.1 CDS HI0243 NC_000907.1 271017 271535 R hypothetical protein complement(271017..271535) Haemophilus influenzae Rd KW20 949380 NP_438414.1 CDS tgt NC_000907.1 271600 272748 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(271600..272748) Haemophilus influenzae Rd KW20 949369 NP_438415.1 CDS queA NC_000907.1 273092 274183 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(273092..274183) Haemophilus influenzae Rd KW20 949371 NP_438416.1 CDS HI0246 NC_000907.1 274307 274753 R hypothetical protein complement(274307..274753) Haemophilus influenzae Rd KW20 949373 NP_438418.1 CDS uvrA NC_000907.1 279439 282270 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(279439..282270) Haemophilus influenzae Rd KW20 949621 NP_438419.1 CDS ssb NC_000907.1 282424 282930 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 282424..282930 Haemophilus influenzae Rd KW20 950657 NP_438420.1 CDS HI0251 NC_000907.1 283108 283920 R similar to GB:U04996; TonB complement(283108..283920) Haemophilus influenzae Rd KW20 949372 NP_438421.1 CDS exbD NC_000907.1 283930 284373 R similar to PID:555672 PID:1573218; biopolymer transport protein complement(283930..284373) Haemophilus influenzae Rd KW20 949375 NP_438422.1 CDS exbB NC_000907.1 284377 284829 R similar to PID:555671; transport protein ExbB complement(284377..284829) Haemophilus influenzae Rd KW20 949376 NP_438423.1 CDS bcp NC_000907.1 284998 285465 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(284998..285465) Haemophilus influenzae Rd KW20 949377 NP_438424.1 CDS dapA NC_000907.1 285566 286462 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 285566..286462 Haemophilus influenzae Rd KW20 949381 NP_438425.1 CDS HI0256 NC_000907.1 286573 287220 D similar to SP:P21167 PID:147409 PID:42126 GB:U00096 PID:1788822; lipoprotein 286573..287220 Haemophilus influenzae Rd KW20 949378 NP_438426.1 CDS HI0257 NC_000907.1 287390 287713 D structural determination suggests similarity to dsRNA-binding proteins; similar to YfiA; similar to SP:P17160 GB:X05888 GB:X16334 PID:39270 PID:39276; hypothetical protein 287390..287713 Haemophilus influenzae Rd KW20 949379 NP_438427.1 CDS HI0258 NC_000907.1 288442 289434 R similar to PID:1857120; glycosyl transferase complement(288442..289434) Haemophilus influenzae Rd KW20 949647 NP_438428.1 CDS HI0260 NC_000907.1 289511 290098 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase complement(289511..290098) Haemophilus influenzae Rd KW20 949383 NP_438429.1 CDS HI0260.1 NC_000907.1 290110 290835 R catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase complement(290110..290835) Haemophilus influenzae Rd KW20 950779 NP_438430.1 CDS HI0261 NC_000907.1 290912 291955 D similar to GB:L21026 PID:311045; lipopolysaccharide biosynthesis protein 290912..291955 Haemophilus influenzae Rd KW20 950896 NP_438431.1 CDS HI0262 NC_000907.1 292279 294450 D similar to SP:P45357 PID:595326; heme-hemopexin utilization protein C 292279..294450 Haemophilus influenzae Rd KW20 950895 NP_438432.1 CDS hxuB NC_000907.1 294525 296222 D similar to SP:P45356 PID:1573229; heme/hemopexin-binding protein B 294525..296222 Haemophilus influenzae Rd KW20 949385 NP_438433.1 CDS hxuA NC_000907.1 296234 298951 D similar to GB:U08348 PID:540014; heme-hemopexin utilization protein A 296234..298951 Haemophilus influenzae Rd KW20 949388 NP_438434.1 CDS HI0265 NC_000907.1 299047 299403 R similar to SP:P31055 PID:882580 GB:U00096 PID:1789438; dihydroneopterin aldolase complement(299047..299403) Haemophilus influenzae Rd KW20 949403 NP_438435.1 CDS HI0266 NC_000907.1 299486 300085 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 299486..300085 Haemophilus influenzae Rd KW20 949419 NP_438436.1 CDS narQ NC_000907.1 300127 301830 D similar to GB:M94724 SP:P27896 GB:X65714 PID:146928 PID:581139; nitrate/nitrite sensor protein NarQ 300127..301830 Haemophilus influenzae Rd KW20 949389 NP_438437.1 CDS murB NC_000907.1 301840 302865 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 301840..302865 Haemophilus influenzae Rd KW20 949392 NP_438438.1 CDS rpoH NC_000907.1 302991 303836 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 302991..303836 Haemophilus influenzae Rd KW20 949393 NP_438439.1 CDS HI0270 NC_000907.1 303876 304808 R similar to SP:P33371 PID:405871 GB:U00096 PID:1788462; hypothetical protein complement(303876..304808) Haemophilus influenzae Rd KW20 950625 NP_438440.1 CDS djlA NC_000907.1 304808 305674 R functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein complement(304808..305674) Haemophilus influenzae Rd KW20 949410 NP_438441.1 CDS pyrE NC_000907.1 305753 306394 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(305753..306394) Haemophilus influenzae Rd KW20 949395 NP_438442.1 CDS rph NC_000907.1 306418 307134 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(306418..307134) Haemophilus influenzae Rd KW20 949396 NP_438443.1 CDS gltX NC_000907.1 307435 308877 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(307435..308877) Haemophilus influenzae Rd KW20 949397 NP_438444.1 CDS HI0275 NC_000907.1 309627 311282 D hypothetical protein 309627..311282 Haemophilus influenzae Rd KW20 949970 NP_438445.1 CDS rbn NC_000907.1 311302 312111 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN complement(311302..312111) Haemophilus influenzae Rd KW20 949791 NP_438446.1 CDS HI0277 NC_000907.1 312108 312593 R similar to GB:L20251 SP:P37052 PID:410154 GB:U00096 PID:1787484; hypothetical protein complement(312108..312593) Haemophilus influenzae Rd KW20 949404 NP_438448.2 CDS udp NC_000907.1 313495 314253 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 313495..314253 Haemophilus influenzae Rd KW20 950640 NP_438449.1 CDS HI0281 NC_000907.1 314478 315794 R similar to SP:P37643 PID:466660 GB:U00096 PID:1789941; transporter complement(314478..315794) Haemophilus influenzae Rd KW20 950652 NP_438450.1 CDS HI0282 NC_000907.1 315850 316593 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(315850..316593) Haemophilus influenzae Rd KW20 949409 NP_438451.1 CDS menD NC_000907.1 316654 318360 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(316654..318360) Haemophilus influenzae Rd KW20 949474 NP_438452.1 CDS menF NC_000907.1 318376 319668 R synthesizes isochorismate acid from chorismate; menaquinone-specific isochorismate synthase complement(318376..319668) Haemophilus influenzae Rd KW20 949812 NP_438453.1 CDS HI0286 NC_000907.1 319804 321018 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 319804..321018 Haemophilus influenzae Rd KW20 949411 NP_438454.1 CDS mtr NC_000907.1 321135 322391 D similar to GB:M58338 SP:P22306 GB:M59862 PID:146894 PID:146896; tryptophan-specific transport protein 321135..322391 Haemophilus influenzae Rd KW20 949413 NP_438455.1 CDS sdaA NC_000907.1 322500 323867 R similar to GB:M28695 SP:P16095 PID:290464 GB:U00096 PID:1736451; L-serine deaminase complement(322500..323867) Haemophilus influenzae Rd KW20 949415 NP_438456.1 CDS sdaC NC_000907.1 323902 325140 R similar to SP:P36559 GB:U01233 PID:402256 PID:882691 GB:U00096; serine transporter complement(323902..325140) Haemophilus influenzae Rd KW20 950177 NP_438457.1 CDS HI0290 NC_000907.1 325363 327531 R similar to GB:AL009126; cation-transporting ATPase complement(325363..327531) Haemophilus influenzae Rd KW20 949726 NP_438458.1 CDS HI0291 NC_000907.1 327506 327712 R mercury transport-like protein complement(327506..327712) Haemophilus influenzae Rd KW20 949416 NP_438459.1 CDS merP NC_000907.1 327787 327993 R similar to GB:X73112 PID:483769 SP:Q51770; mercuric ion scavenger protein complement(327787..327993) Haemophilus influenzae Rd KW20 949615 NP_438460.1 CDS HI0293 NC_000907.1 328070 328456 D similar to GB:U00096 SP:P77565 PID:1773169 PID:1786695; MerR family transcriptional regulator 328070..328456 Haemophilus influenzae Rd KW20 949535 NP_438461.1 CDS metJ NC_000907.1 328470 328787 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(328470..328787) Haemophilus influenzae Rd KW20 949418 NP_438462.1 CDS rho NC_000907.1 329034 330296 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 329034..330296 Haemophilus influenzae Rd KW20 949491 NP_438463.1 CDS hopD NC_000907.1 330350 331042 R similar to SP:P25960 GB:L28106 PID:145410 PID:451905 PID:606269; type 4 prepilin-like protein specific leader peptidase complement(330350..331042) Haemophilus influenzae Rd KW20 950669 NP_438464.1 CDS HI0297 NC_000907.1 331039 332259 R similar to GB:M32066 SP:P22609 PID:151066; type IV pilin secretion protein complement(331039..332259) Haemophilus influenzae Rd KW20 950200 NP_438465.1 CDS HI0298 NC_000907.1 332256 333650 R similar to GB:M32066 SP:P22608 GB:S43866 PID:151065; protein transport protein complement(332256..333650) Haemophilus influenzae Rd KW20 949957 NP_438466.1 CDS HI0299 NC_000907.1 333647 334096 R similar to GB:D26562 SP:P36647 GB:L28105 PID:473777 PID:456042; prepilin peptidase-dependent protein D complement(333647..334096) Haemophilus influenzae Rd KW20 949521 NP_438467.1 CDS ampD NC_000907.1 334212 334766 D similar to GB:D26562 SP:P13016 GB:L28105 GB:X15237 PID:40908; N-acetyl-anhydromuranmyl-L-alanine amidase 334212..334766 Haemophilus influenzae Rd KW20 949420 NP_438468.1 CDS HI0301 NC_000907.1 335399 336298 D similar to GB:U00096 PID:1778577 PID:1786879; hemolysin 335399..336298 Haemophilus influenzae Rd KW20 949422 NP_438469.2 CDS lnt NC_000907.1 336321 337850 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 336321..337850 Haemophilus influenzae Rd KW20 949425 NP_438470.1 CDS HI0303 NC_000907.1 337900 338637 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 337900..338637 Haemophilus influenzae Rd KW20 950245 NP_438471.1 CDS HI0304 NC_000907.1 338634 339194 D similar to PID:882477 SP:P52049 GB:U00096 PID:1789317; hypothetical protein 338634..339194 Haemophilus influenzae Rd KW20 949387 NP_438472.1 CDS HI0305 NC_000907.1 339194 339613 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 339194..339613 Haemophilus influenzae Rd KW20 950747 NP_438473.1 CDS rdgC NC_000907.1 339663 340571 R Required for efficient pilin antigenic variation; recombination associated protein complement(339663..340571) Haemophilus influenzae Rd KW20 949925 NP_438474.1 CDS proC NC_000907.1 340637 341452 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 340637..341452 Haemophilus influenzae Rd KW20 949427 NP_438475.1 CDS HI0308 NC_000907.1 341452 342618 D transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 341452..342618 Haemophilus influenzae Rd KW20 950679 NP_438476.1 CDS xerD NC_000907.1 342649 343542 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 342649..343542 Haemophilus influenzae Rd KW20 949437 NP_438477.1 CDS HI0310 NC_000907.1 343715 344002 D hypothetical protein 343715..344002 Haemophilus influenzae Rd KW20 949975 NP_438478.1 CDS ruvB NC_000907.1 344054 345061 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(344054..345061) Haemophilus influenzae Rd KW20 950827 NP_438479.1 CDS ruvA NC_000907.1 345069 345683 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(345069..345683) Haemophilus influenzae Rd KW20 949429 NP_438480.1 CDS ruvC NC_000907.1 345746 346318 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(345746..346318) Haemophilus influenzae Rd KW20 949435 NP_438481.1 CDS HI0315 NC_000907.1 346365 347105 R similar to GB:D10165 SP:P24237 PID:216652 PID:42173 GB:U00096; hypothetical protein complement(346365..347105) Haemophilus influenzae Rd KW20 949441 NP_438482.2 CDS ntpA NC_000907.1 347265 347729 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(347265..347729) Haemophilus influenzae Rd KW20 949449 NP_438483.1 CDS aspS NC_000907.1 347763 349529 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(347763..349529) Haemophilus influenzae Rd KW20 949430 NP_438484.1 CDS HI0318 NC_000907.1 349748 350266 D similar to SP:P54158 PID:1256620 GB:AL009126; hypothetical protein 349748..350266 Haemophilus influenzae Rd KW20 949431 NP_438485.1 CDS yecO NC_000907.1 350319 351044 D YecO; contains bound cofactor S-adenosyl-L-homocysteine; similar to GB:U00096 PID:1788177; S-adenosyl-L-methionine-dependent methyltransferase 350319..351044 Haemophilus influenzae Rd KW20 949432 NP_438486.1 CDS vapB NC_000907.1 351138 351374 D similar to GB:L22308 GB:L31763 GB:M74565 PID:145069 PID:438535; virulence-associated protein B 351138..351374 Haemophilus influenzae Rd KW20 949433 NP_438487.1 CDS HI0322 NC_000907.1 351371 351775 D similar to GB:L22308 GB:L31763 GB:M74565 PID:145068 PID:438534; virulence-associated protein C 351371..351775 Haemophilus influenzae Rd KW20 949434 NP_438488.1 CDS gloA NC_000907.1 351842 352249 D similar to GB:U00096 SP:Q59384 PID:1354845 PID:1711245 PID:1787940; lactoylglutathione lyase 351842..352249 Haemophilus influenzae Rd KW20 949438 NP_438489.1 CDS rnt NC_000907.1 352323 353012 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 352323..353012 Haemophilus influenzae Rd KW20 949924 NP_438490.1 CDS HI0325 NC_000907.1 353326 354678 D similar to GB:AL009126; hypothetical protein 353326..354678 Haemophilus influenzae Rd KW20 950706 NP_438492.3 CDS efp NC_000907.1 355648 356214 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(355648..356214) Haemophilus influenzae Rd KW20 949790 NP_438493.1 CDS HI0329 NC_000907.1 356252 357268 D similar to GB:U14003 SP:P39280 PID:536990 GB:U00096 PID:1790589; hypothetical protein 356252..357268 Haemophilus influenzae Rd KW20 949459 NP_438494.1 CDS oapA NC_000907.1 357367 358662 D similar to GB:L42023 SP:P44415 PID:1003551 PID:1222255 PID:595942; opacity associated protein 357367..358662 Haemophilus influenzae Rd KW20 949442 NP_438495.1 CDS oapB NC_000907.1 358722 359126 D similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943; opacity associated protein OapB 358722..359126 Haemophilus influenzae Rd KW20 950648 NP_438496.1 CDS recO NC_000907.1 359129 359839 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 359129..359839 Haemophilus influenzae Rd KW20 950611 NP_438497.1 CDS rumA NC_000907.1 359839 361155 D in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 359839..361155 Haemophilus influenzae Rd KW20 949426 NP_438498.1 CDS relA NC_000907.1 361233 363464 D similar to GB:J04039 SP:P11585 PID:147562 PID:882678 GB:U00096; GTP pyrophosphokinase 361233..363464 Haemophilus influenzae Rd KW20 950822 NP_438499.1 CDS dgkA NC_000907.1 363479 363835 D similar to GB:U00006 SP:P00556 GB:K00127 PID:396377 PID:457112; diacylglycerol kinase 363479..363835 Haemophilus influenzae Rd KW20 949443 NP_438500.1 CDS mogA NC_000907.1 363918 364511 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 363918..364511 Haemophilus influenzae Rd KW20 949444 NP_438501.1 CDS glnB NC_000907.1 364513 364851 D similar to GB:U00096 PID:1788904 PID:1799977; nitrogen regulatory protein P-II 364513..364851 Haemophilus influenzae Rd KW20 949445 NP_438502.1 CDS HI0338 NC_000907.1 364851 365897 D similar to GB:U00096 PID:1787885; hypothetical protein 364851..365897 Haemophilus influenzae Rd KW20 949451 NP_438503.1 CDS priA NC_000907.1 365938 368130 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(365938..368130) Haemophilus influenzae Rd KW20 950761 NP_438504.1 CDS trmB NC_000907.1 368213 368953 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 368213..368953 Haemophilus influenzae Rd KW20 949446 NP_438505.1 CDS HI0341 NC_000907.1 369038 369382 D similar to SP:P38521 PID:882488 GB:U00096 PID:1789329; hypothetical protein 369038..369382 Haemophilus influenzae Rd KW20 949447 NP_438507.1 CDS napD NC_000907.1 370110 370391 D similar to SP:P33938 PID:405935 GB:U00096 PID:1788535; nitrate reductase assembly protein NapD 370110..370391 Haemophilus influenzae Rd KW20 949452 NP_438509.1 CDS napG NC_000907.1 372967 373806 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic subunit 372967..373806 Haemophilus influenzae Rd KW20 950819 NP_438510.1 CDS napH NC_000907.1 373806 374669 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane subunit 373806..374669 Haemophilus influenzae Rd KW20 949454 NP_438511.1 CDS napB NC_000907.1 374666 375118 D contains two heme groups; similar to SP:P33933 PID:405928 GB:U00096 PID:1788531; nitrate reductase 374666..375118 Haemophilus influenzae Rd KW20 949780 NP_438512.1 CDS napC NC_000907.1 375133 375735 D similar to SP:P33932 PID:405927 GB:U00096 PID:1788530; cytochrome C-type protein 375133..375735 Haemophilus influenzae Rd KW20 949803 NP_438513.1 CDS adk NC_000907.1 375895 376539 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(375895..376539) Haemophilus influenzae Rd KW20 949455 NP_438514.1 CDS HI0350 NC_000907.1 376624 377901 R similar to GB:U00096 SP:P36670 PID:1773117 PID:1786636 PID:563855; permease complement(376624..377901) Haemophilus influenzae Rd KW20 949456 NP_438515.1 CDS galE NC_000907.1 378043 379059 R similar to SP:P24325 GB:L42023 PID:1003592 PID:1222277 PID:43589; UDP-glucose 4-epimerase complement(378043..379059) Haemophilus influenzae Rd KW20 949642 NP_438516.1 CDS HI0352 NC_000907.1 379232 379927 R similar to SP:P24324 GB:X57315 PID:43588; hypothetical protein complement(379232..379927) Haemophilus influenzae Rd KW20 949950 NP_438517.1 CDS HI0354 NC_000907.1 380643 381365 D similar to PID:1184189 GB:U00096 SP:Q47538 PID:1384059 PID:1657561; ABC transporter ATP-binding protein 380643..381365 Haemophilus influenzae Rd KW20 949457 NP_438518.1 CDS HI0355 NC_000907.1 381362 382099 D similar to GB:L16808 SP:P40401 PID:438473 PID:1903040 GB:AL009126; ABC transporter permease 381362..382099 Haemophilus influenzae Rd KW20 949458 NP_438519.1 CDS HI0357 NC_000907.1 382121 383065 D similar to SP:P42883 SP:P43534 SP:P47183 PID:1015913 PID:1302455; thiamine biosynthesis protein 382121..383065 Haemophilus influenzae Rd KW20 949462 NP_438520.1 CDS HI0358 NC_000907.1 383075 383722 D similar to GB:AE000511 PID:2314455; transcriptional activator 383075..383722 Haemophilus influenzae Rd KW20 949463 NP_438521.1 CDS yfeD NC_000907.1 383822 384637 R similar to PID:1245464 SP:Q56955 PID:1245467; iron (chelated) ABC transporter permease complement(383822..384637) Haemophilus influenzae Rd KW20 949465 NP_438522.1 CDS yfeC NC_000907.1 384630 385478 R similar to PID:1245464 SP:Q56954 PID:1245466; iron (chelated) ABC transporter permease complement(384630..385478) Haemophilus influenzae Rd KW20 950649 NP_438523.1 CDS yfeB NC_000907.1 385482 386402 R similar to PID:1245464 PID:1245465; iron (chelated) transporter ATP-binding protein complement(385482..386402) Haemophilus influenzae Rd KW20 950559 NP_438524.1 CDS yfeA NC_000907.1 386402 387283 R similar to PID:1245464; iron-chelated ABC transporter substrate-binding protein complement(386402..387283) Haemophilus influenzae Rd KW20 950634 NP_438525.1 CDS HI0364 NC_000907.1 387648 388526 R similar to SP:P33364 GB:X01067 PID:405864 PID:808967 GB:U00096; penicillin-binding protein 7 complement(387648..388526) Haemophilus influenzae Rd KW20 949374 NP_438526.1 CDS HI0365 NC_000907.1 388752 389924 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 388752..389924 Haemophilus influenzae Rd KW20 949466 NP_438527.1 CDS HI0366 NC_000907.1 390026 390565 D similar to PID:1162960; fimbrial biogenesis and twitching motility protein 390026..390565 Haemophilus influenzae Rd KW20 949468 NP_438528.1 CDS HI0367 NC_000907.1 390637 391548 D similar to SP:P27434 GB:D21149 GB:U02965 GB:X64451 PID:41541; hypothetical protein 390637..391548 Haemophilus influenzae Rd KW20 949469 NP_438529.1 CDS ispG NC_000907.1 391558 392664 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 391558..392664 Haemophilus influenzae Rd KW20 949471 NP_438530.1 CDS hisS NC_000907.1 392674 393945 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 392674..393945 Haemophilus influenzae Rd KW20 950203 NP_438531.1 CDS HI0370 NC_000907.1 393962 394576 D similar to GB:U00096 PID:1788860; hypothetical protein 393962..394576 Haemophilus influenzae Rd KW20 949833 NP_438532.1 CDS HI0371 NC_000907.1 394627 394821 R similar to SP:P37096 GB:U00096 PID:1788873; hypothetical protein complement(394627..394821) Haemophilus influenzae Rd KW20 949472 NP_438533.1 CDS fdx-1 NC_000907.1 394821 395162 R similar to GB:M88654 SP:P25528 PID:145915 GB:U00096 PID:1788874; ferredoxin complement(394821..395162) Haemophilus influenzae Rd KW20 949473 NP_438534.1 CDS hscA NC_000907.1 395202 397061 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(395202..397061) Haemophilus influenzae Rd KW20 949476 NP_438535.1 CDS HI0374 NC_000907.1 397080 397766 R hypothetical protein complement(397080..397766) Haemophilus influenzae Rd KW20 950642 NP_438536.1 CDS hscB NC_000907.1 397817 398341 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(397817..398341) Haemophilus influenzae Rd KW20 949448 NP_438537.1 CDS HI0376 NC_000907.1 398354 398677 R similar to SP:P36539; hypothetical protein complement(398354..398677) Haemophilus influenzae Rd KW20 950630 NP_438538.2 CDS iscU NC_000907.1 398734 399150 R similar to PID:2271522; scaffold protein complement(398734..399150) Haemophilus influenzae Rd KW20 949477 NP_438539.2 CDS nifS NC_000907.1 399174 400388 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(399174..400388) Haemophilus influenzae Rd KW20 949479 NP_438540.1 CDS HI0379 NC_000907.1 400455 400907 R similar to GB:U00096 PID:1788880; hypothetical protein complement(400455..400907) Haemophilus influenzae Rd KW20 949480 NP_438541.1 CDS HI0380 NC_000907.1 400960 401685 R similar to GB:U00096 PID:1788881; hypothetical protein complement(400960..401685) Haemophilus influenzae Rd KW20 949482 NP_438542.1 CDS pal NC_000907.1 402127 402588 R similar to SP:P10324 PID:1573351 SP:P10324 GB:M18878 PID:1573351; peptidoglycan-associated outer membrane lipoprotein complement(402127..402588) Haemophilus influenzae Rd KW20 949485 NP_438543.1 CDS tolB NC_000907.1 402612 403895 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(402612..403895) Haemophilus influenzae Rd KW20 949486 NP_438544.1 CDS tolA NC_000907.1 403937 405055 R inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA complement(403937..405055) Haemophilus influenzae Rd KW20 949487 NP_438545.1 CDS tolR NC_000907.1 405071 405490 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR complement(405071..405490) Haemophilus influenzae Rd KW20 949489 NP_438546.1 CDS tolQ NC_000907.1 405562 406248 R similar to SP:P05828 PID:1128978 GB:U00096 PID:1651329 PID:1786958; colicin transport protein complement(405562..406248) Haemophilus influenzae Rd KW20 950751 NP_438547.1 CDS HI0386 NC_000907.1 406265 406675 R similar to SP:P08999 PID:1128977 GB:U00096 PID:1786957; hypothetical protein complement(406265..406675) Haemophilus influenzae Rd KW20 950554 NP_438548.1 CDS dinG NC_000907.1 407000 408922 D similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110; ATP-dependent helicase 407000..408922 Haemophilus influenzae Rd KW20 949750 NP_438549.1 CDS HI0388 NC_000907.1 408935 409645 D similar to GB:U00096 SP:P76256 PID:1736440 PID:1736446 PID:1788109; hypothetical protein 408935..409645 Haemophilus influenzae Rd KW20 950019 NP_438550.1 CDS HI0389 NC_000907.1 409670 410221 D similar to GB:U00039 SP:P37194 GB:L23635 PID:387932 PID:466643; outer membrane protein 409670..410221 Haemophilus influenzae Rd KW20 949490 NP_438551.1 CDS fadD NC_000907.1 410264 411952 D Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 410264..411952 Haemophilus influenzae Rd KW20 950680 NP_438552.1 CDS rnd NC_000907.1 411952 413151 D similar to SP:P09155 GB:X07055 GB:X70994 PID:581071 PID:581215; ribonuclease D 411952..413151 Haemophilus influenzae Rd KW20 950674 NP_438555.1 CDS HI0393 NC_000907.1 415151 416242 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(415151..416242) Haemophilus influenzae Rd KW20 949492 NP_438556.1 CDS pth NC_000907.1 416291 416875 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(416291..416875) Haemophilus influenzae Rd KW20 949493 NP_438557.1 CDS HI0395 NC_000907.1 417042 417350 D similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971; hypothetical protein 417042..417350 Haemophilus influenzae Rd KW20 949524 NP_438558.1 CDS HI0396 NC_000907.1 417353 418567 D similar to SP:P27431 GB:U00096 PID:1787373; hypothetical protein 417353..418567 Haemophilus influenzae Rd KW20 950708 NP_438559.1 CDS xseA NC_000907.1 418569 419888 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 418569..419888 Haemophilus influenzae Rd KW20 949494 NP_438560.2 CDS HI0398 NC_000907.1 420086 420718 D similar to SP:P36651 PID:882564 GB:U00096 PID:1789412; hypothetical protein 420086..420718 Haemophilus influenzae Rd KW20 949499 NP_438561.1 CDS icc NC_000907.1 420728 421552 D similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096; cyclic 3',5'-adenosine monophosphate phosphodiesterase 420728..421552 Haemophilus influenzae Rd KW20 949501 NP_438562.1 CDS HI0400 NC_000907.1 421650 421937 R similar to GB:U00096 PID:1788685; hypothetical protein complement(421650..421937) Haemophilus influenzae Rd KW20 950654 NP_438563.1 CDS fadL NC_000907.1 422144 423523 D similar to GB:M60607 SP:P10384 GB:Y00552 PID:145910 PID:41372; long-chain fatty acid transport protein 422144..423523 Haemophilus influenzae Rd KW20 949945 NP_438564.1 CDS HI0402 NC_000907.1 423567 424139 D dat1; similar to SP:P11742 GB:X15659 PID:39876 GB:AL009126; methylated-DNA-protein-cysteine methyltransferase 423567..424139 Haemophilus influenzae Rd KW20 949561 NP_438565.1 CDS mutH NC_000907.1 424136 424807 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 424136..424807 Haemophilus influenzae Rd KW20 949640 NP_438566.1 CDS mesJ NC_000907.1 424804 426096 R similar to GB:U00096 PID:1552765 PID:1786386 PID:971394; cell cycle protein complement(424804..426096) Haemophilus influenzae Rd KW20 949503 NP_438567.1 CDS HI0405 NC_000907.1 426096 426962 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(426096..426962) Haemophilus influenzae Rd KW20 949504 NP_438568.1 CDS accA NC_000907.1 427035 427982 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(427035..427982) Haemophilus influenzae Rd KW20 949505 NP_438569.1 CDS HI0407 NC_000907.1 428072 428857 R similar to PID:1054959 GB:U00096 PID:1788166; hypothetical protein complement(428072..428857) Haemophilus influenzae Rd KW20 949507 NP_438570.1 CDS yebM NC_000907.1 428857 429663 R similar to SP:P52648 GB:U00096 PID:1736501 PID:1736505 PID:1788165; ABC transporter ATP-binding protein complement(428857..429663) Haemophilus influenzae Rd KW20 949513 NP_438571.1 CDS HI0409 NC_000907.1 429835 431262 D similar to GB:M77039 SP:P24204 PID:146890 PID:1054957 GB:U00096; hypothetical protein 429835..431262 Haemophilus influenzae Rd KW20 949412 NP_438572.1 CDS tyrR NC_000907.1 431377 432333 D contains a C-terminal HTH DNA-binding domain; similar to GB:M12114 SP:P07604 PID:148092 GB:U00096 PID:1742168; transcriptional regulatory protein 431377..432333 Haemophilus influenzae Rd KW20 950074 NP_438573.1 CDS hfq NC_000907.1 432430 432705 R Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq complement(432430..432705) Haemophilus influenzae Rd KW20 950678 NP_438574.1 CDS HI0412 NC_000907.1 432796 433764 R catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(432796..433764) Haemophilus influenzae Rd KW20 949514 NP_438575.2 CDS rne NC_000907.1 434185 436992 D similar to SP:P21513 GB:X67470 GB:L23942 GB:M62747 GB:X54309; ribonuclease E 434185..436992 Haemophilus influenzae Rd KW20 949934 NP_438576.1 CDS HI0414 NC_000907.1 437224 437436 D hypothetical protein 437224..437436 Haemophilus influenzae Rd KW20 949402 NP_438577.1 CDS HI0415 NC_000907.1 437760 438557 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 437760..438557 Haemophilus influenzae Rd KW20 949516 NP_438578.1 CDS thiD NC_000907.1 438550 439359 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 438550..439359 Haemophilus influenzae Rd KW20 949517 NP_438579.1 CDS thiE NC_000907.1 439370 440050 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 439370..440050 Haemophilus influenzae Rd KW20 949518 NP_438580.1 CDS HI0418 NC_000907.1 439995 441338 D similar to GB:L42023 SP:P44610 PID:1003458 PID:1222206 PID:1204537; transporter 439995..441338 Haemophilus influenzae Rd KW20 950811 NP_438581.1 CDS HI0419 NC_000907.1 441507 442889 D similar to GB:U00096 SP:P76403 PID:1736789 PID:1736801 PID:1788397; protease 441507..442889 Haemophilus influenzae Rd KW20 949394 NP_438582.1 CDS HI0420 NC_000907.1 443031 443330 D hypothetical protein 443031..443330 Haemophilus influenzae Rd KW20 949520 NP_438583.1 CDS srmB NC_000907.1 444029 445348 R facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB complement(444029..445348) Haemophilus influenzae Rd KW20 949526 NP_438584.1 CDS HI0423 NC_000907.1 445394 446116 D similar to SP:P31825 GB:U00096 PID:1788929; hypothetical protein 445394..446116 Haemophilus influenzae Rd KW20 949527 NP_438585.1 CDS HI0424 NC_000907.1 446149 447204 R similar to SP:P33635 GB:U00096 PID:1788935; rRNA methylase complement(446149..447204) Haemophilus influenzae Rd KW20 949529 NP_438586.1 CDS pssA NC_000907.1 447351 448718 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 447351..448718 Haemophilus influenzae Rd KW20 950510 NP_438587.1 CDS fadR NC_000907.1 448763 449488 R Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator complement(448763..449488) Haemophilus influenzae Rd KW20 949831 NP_438588.2 CDS nhaB NC_000907.1 449613 451157 D involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 449613..451157 Haemophilus influenzae Rd KW20 949530 NP_438589.1 CDS dsbB NC_000907.1 451167 451700 D disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 451167..451700 Haemophilus influenzae Rd KW20 950809 NP_438590.1 CDS glmS NC_000907.1 451754 453586 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(451754..453586) Haemophilus influenzae Rd KW20 950659 NP_438591.2 CDS HI0430 NC_000907.1 453698 453970 R similar to SP:P02342 GB:D12624 GB:X05994 PID:216565 PID:396339; DNA-binding protein HU-alpha complement(453698..453970) Haemophilus influenzae Rd KW20 950715 NP_438592.1 CDS HI0431 NC_000907.1 454110 454700 R similar to SP:P32680 PID:396338 GB:U00096 PID:1790432; hypothetical protein complement(454110..454700) Haemophilus influenzae Rd KW20 950606 NP_438593.1 CDS nudC NC_000907.1 454736 455530 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(454736..455530) Haemophilus influenzae Rd KW20 949531 NP_438594.1 CDS HI0433 NC_000907.1 455597 456193 R cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein complement(455597..456193) Haemophilus influenzae Rd KW20 950313 NP_438595.1 CDS comF NC_000907.1 456269 456958 R similar to GB:M59751 SP:P31773 PID:1573409; competence protein F complement(456269..456958) Haemophilus influenzae Rd KW20 950316 NP_438596.1 CDS comE NC_000907.1 456967 458304 R similar to GB:M62809 SP:P31772 PID:1573410; competence protein E complement(456967..458304) Haemophilus influenzae Rd KW20 950687 NP_438597.1 CDS comD NC_000907.1 458314 458727 R similar to GB:M62809 SP:P31771 PID:1573411; competence protein D complement(458314..458727) Haemophilus influenzae Rd KW20 950663 NP_438598.1 CDS comC NC_000907.1 458724 459245 R similar to GB:M62809 SP:P31770 PID:1573412; competence protein C complement(458724..459245) Haemophilus influenzae Rd KW20 950528 NP_438599.1 CDS comB NC_000907.1 459242 459748 R similar to GB:M62809 SP:P31769 PID:1573413; competence protein B complement(459242..459748) Haemophilus influenzae Rd KW20 949525 NP_438600.1 CDS comA NC_000907.1 459749 460546 R similar to GB:M62809 SP:P31768 PID:1573414; competence protein A complement(459749..460546) Haemophilus influenzae Rd KW20 949534 NP_438601.1 CDS ponA NC_000907.1 460645 463239 D similar to SP:P02918 GB:X02164 PID:581194 PID:606330 GB:U00096; penicillin-binding protein 1A 460645..463239 Haemophilus influenzae Rd KW20 949537 NP_438602.1 CDS HI0441 NC_000907.1 463327 464172 D OrfJ; similar to GB:M62809 SP:P31777 PID:1573417; hypothetical protein 463327..464172 Haemophilus influenzae Rd KW20 949523 NP_438603.2 CDS ybaB NC_000907.1 464325 464654 D forms homodimers; coexpressed with recR; similar to GB:M38777 SP:P17577 GB:X04487 PID:145298 PID:43322; hypothetical protein 464325..464654 Haemophilus influenzae Rd KW20 950773 NP_438604.1 CDS recR NC_000907.1 464716 465318 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 464716..465318 Haemophilus influenzae Rd KW20 949512 NP_438605.1 CDS topB NC_000907.1 465334 467289 D decatenates replicating daughter chromosomes; DNA topoisomerase III 465334..467289 Haemophilus influenzae Rd KW20 949541 NP_438606.1 CDS secG NC_000907.1 467398 467736 D similar to GB:D16463 SP:P33582 GB:U01376 PID:431135 PID:606113; preprotein translocase subunit SecG 467398..467736 Haemophilus influenzae Rd KW20 949417 NP_438607.1 CDS fruA NC_000907.1 468265 469935 R similar to SP:P20966 GB:M23196 PID:405893 PID:450372 GB:U00096; PTS system fructose-specific transporter subunit IIBC complement(468265..469935) Haemophilus influenzae Rd KW20 949670 NP_438608.1 CDS fruK NC_000907.1 469937 470878 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(469937..470878) Haemophilus influenzae Rd KW20 949542 NP_438609.1 CDS fruB NC_000907.1 470880 472379 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; PTS system fructose-specific transporter subunit IIA/HPr protein complement(470880..472379) Haemophilus influenzae Rd KW20 950651 NP_438610.1 CDS HI0449 NC_000907.1 472451 472987 R hypothetical protein complement(472451..472987) Haemophilus influenzae Rd KW20 949746 NP_438611.1 CDS vapD NC_000907.1 473074 473349 R similar to GB:L22307 GB:L31763 GB:M74565 PID:145067 PID:438533; virulence-associated protein D complement(473074..473349) Haemophilus influenzae Rd KW20 949544 NP_438612.1 CDS HI0451 NC_000907.1 473358 473549 R similar to PID:1196479; hypothetical protein complement(473358..473549) Haemophilus influenzae Rd KW20 950826 NP_438613.1 CDS HI0452 NC_000907.1 473621 474919 R similar to GB:U14003 SP:P39319 PID:537059 GB:U00096 PID:1790664; hypothetical protein complement(473621..474919) Haemophilus influenzae Rd KW20 949660 NP_438614.1 CDS HI0453 NC_000907.1 474970 475494 R similar to GB:AE000511 PID:2313105; hypothetical protein complement(474970..475494) Haemophilus influenzae Rd KW20 949624 NP_438615.1 CDS HI0454 NC_000907.1 475521 476303 R similar to SP:P37346 GB:U00096 PID:1787342; hypothetical protein complement(475521..476303) Haemophilus influenzae Rd KW20 949545 NP_438616.1 CDS holB NC_000907.1 476358 477341 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(476358..477341) Haemophilus influenzae Rd KW20 949546 NP_438617.2 CDS tmk NC_000907.1 477338 477997 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(477338..477997) Haemophilus influenzae Rd KW20 949547 NP_438618.1 CDS HI0457 NC_000907.1 477987 479030 R similar to GB:U00096 PID:1510185 PID:1787339; hypothetical protein complement(477987..479030) Haemophilus influenzae Rd KW20 950653 NP_438619.1 CDS HI0458 NC_000907.1 479100 480041 R similar to SP:P21202 GB:M68521 PID:147119 PID:216478 GB:U00096; stationary-phase survival protein SurA complement(479100..480041) Haemophilus influenzae Rd KW20 949829 NP_438620.1 CDS pyrR NC_000907.1 480112 480651 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase complement(480112..480651) Haemophilus influenzae Rd KW20 949777 NP_438621.1 CDS mazG NC_000907.1 480783 481574 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 480783..481574 Haemophilus influenzae Rd KW20 949607 NP_438622.1 CDS HI0461 NC_000907.1 481624 482499 R similar to SP:P32181; hypothetical protein complement(481624..482499) Haemophilus influenzae Rd KW20 949548 NP_438623.1 CDS lon NC_000907.1 482692 485103 D similar to GB:M38347 SP:P08177 GB:J03896 GB:L12349 GB:L20572; ATP-dependent proteinase 482692..485103 Haemophilus influenzae Rd KW20 949549 NP_438624.1 CDS HI0463 NC_000907.1 485219 486370 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 485219..486370 Haemophilus influenzae Rd KW20 949551 NP_438625.1 CDS rpiA NC_000907.1 486503 487162 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 486503..487162 Haemophilus influenzae Rd KW20 949550 NP_438626.1 CDS serA NC_000907.1 487192 488424 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 487192..488424 Haemophilus influenzae Rd KW20 950636 NP_438627.1 CDS HI0466 NC_000907.1 488468 489310 R similar to PID:887848 GB:U00096 SP:P39179 PID:1789265; hypothetical protein complement(488468..489310) Haemophilus influenzae Rd KW20 949552 NP_438628.3 CDS HI0467 NC_000907.1 489320 490183 R similar to GB:L10328 SP:P23839 GB:X14235 PID:290494 PID:42721; hypothetical protein complement(489320..490183) Haemophilus influenzae Rd KW20 949553 NP_438629.1 CDS hisG NC_000907.1 490631 491542 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 490631..491542 Haemophilus influenzae Rd KW20 949555 NP_438630.1 CDS hisD NC_000907.1 491635 492918 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 491635..492918 Haemophilus influenzae Rd KW20 949557 NP_438631.1 CDS hisC NC_000907.1 492987 494090 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 492987..494090 Haemophilus influenzae Rd KW20 949558 NP_438632.1 CDS hisB NC_000907.1 494202 495290 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 494202..495290 Haemophilus influenzae Rd KW20 949564 NP_438633.1 CDS hisH NC_000907.1 495356 495955 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 495356..495955 Haemophilus influenzae Rd KW20 949532 NP_438634.1 CDS hisA NC_000907.1 495991 496740 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 495991..496740 Haemophilus influenzae Rd KW20 949519 NP_438635.1 CDS hisF NC_000907.1 496722 497498 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 496722..497498 Haemophilus influenzae Rd KW20 949565 NP_438636.1 CDS hisIE NC_000907.1 497498 498163 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 497498..498163 Haemophilus influenzae Rd KW20 949566 NP_438637.1 CDS tyrP NC_000907.1 498427 499629 D similar to GB:M23240 SP:P18199 PID:148089 GB:U00096 PID:1736569; tyrosine-specific transport protein 498427..499629 Haemophilus influenzae Rd KW20 950656 NP_438638.1 CDS atpC NC_000907.1 499815 500243 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(499815..500243) Haemophilus influenzae Rd KW20 950629 NP_438639.1 CDS atpD NC_000907.1 500273 501646 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(500273..501646) Haemophilus influenzae Rd KW20 950675 NP_438640.1 CDS atpG NC_000907.1 501663 502532 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(501663..502532) Haemophilus influenzae Rd KW20 949567 NP_438641.1 CDS atpA NC_000907.1 502548 504089 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(502548..504089) Haemophilus influenzae Rd KW20 950615 NP_438642.1 CDS atpH NC_000907.1 504102 504635 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(504102..504635) Haemophilus influenzae Rd KW20 949424 NP_438643.1 CDS atpF NC_000907.1 504648 505118 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(504648..505118) Haemophilus influenzae Rd KW20 949543 NP_438644.1 CDS atpE NC_000907.1 505168 505422 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(505168..505422) Haemophilus influenzae Rd KW20 949568 NP_438645.1 CDS atpB NC_000907.1 505478 506266 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(505478..506266) Haemophilus influenzae Rd KW20 949858 NP_438646.1 CDS HI0485.1 NC_000907.1 506303 506677 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(506303..506677) Haemophilus influenzae Rd KW20 950693 NP_438647.1 CDS gidB NC_000907.1 506803 507414 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(506803..507414) Haemophilus influenzae Rd KW20 950623 NP_438648.1 CDS HI0487 NC_000907.1 507554 507931 R hypothetical protein complement(507554..507931) Haemophilus influenzae Rd KW20 950695 NP_438649.1 CDS HI0488 NC_000907.1 508047 508649 D similar to GB:U00096 PID:1789046; phosphatase/phosphohexomutase 508047..508649 Haemophilus influenzae Rd KW20 949569 NP_438650.1 CDS HI0489 NC_000907.1 508649 509122 D similar to GB:U00096 PID:1789045; hypothetical protein 508649..509122 Haemophilus influenzae Rd KW20 949626 NP_438651.1 CDS luxS NC_000907.1 509452 509955 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 509452..509955 Haemophilus influenzae Rd KW20 950775 NP_438652.1 CDS HI0493 NC_000907.1 510454 510810 D similar to GB:M29945 PID:1197032; hypothetical protein 510454..510810 Haemophilus influenzae Rd KW20 949783 NP_438653.1 CDS aphA NC_000907.1 510901 511609 R Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase complement(join(510901..511410,511409..511609)) Haemophilus influenzae Rd KW20 950561 NP_438654.1 CDS hslV NC_000907.1 511828 512355 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 511828..512355 Haemophilus influenzae Rd KW20 949571 NP_438655.1 CDS hslU NC_000907.1 512366 513700 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 512366..513700 Haemophilus influenzae Rd KW20 950614 NP_438656.2 CDS potD NC_000907.1 513770 514822 R similar to GB:M64519 SP:P23861 PID:147329 GB:U00096 PID:1651550; spermidine/putrescine ABC transporter substrate-binding protein complement(513770..514822) Haemophilus influenzae Rd KW20 950055 NP_438657.1 CDS HI0499 NC_000907.1 514963 516258 D similar to GB:M38433 SP:P37906 PID:1054921 PID:551780 GB:U00096; oxidoreductase 514963..516258 Haemophilus influenzae Rd KW20 949572 NP_438658.2 CDS HI0500 NC_000907.1 516703 517866 D similar to GB:M87049 SP:P27850 PID:148230 GB:U00096 PID:1790266; hypothetical protein 516703..517866 Haemophilus influenzae Rd KW20 949635 NP_438659.1 CDS rbsD NC_000907.1 518034 518453 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 518034..518453 Haemophilus influenzae Rd KW20 949497 NP_438660.1 CDS rbsA NC_000907.1 518467 519948 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 518467..519948 Haemophilus influenzae Rd KW20 950602 NP_438661.1 CDS rbsC NC_000907.1 519961 520932 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 519961..520932 Haemophilus influenzae Rd KW20 949666 NP_438662.1 CDS rbsB NC_000907.1 520952 521830 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 520952..521830 Haemophilus influenzae Rd KW20 949573 NP_438663.1 CDS rbsK NC_000907.1 521928 522848 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 521928..522848 Haemophilus influenzae Rd KW20 949575 NP_438664.1 CDS rbsR NC_000907.1 522876 523874 D similar to GB:L10328 SP:P25551 GB:D10466 GB:M13169 PID:147517; RBS repressor 522876..523874 Haemophilus influenzae Rd KW20 949576 NP_438665.1 CDS HI0507 NC_000907.1 523980 524531 D similar to PID:882531 SP:P52082 GB:U00096 PID:1789376; hypothetical protein 523980..524531 Haemophilus influenzae Rd KW20 949655 NP_438666.1 CDS menG NC_000907.1 524671 525159 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(524671..525159) Haemophilus influenzae Rd KW20 949667 NP_438667.2 CDS menA NC_000907.1 525211 526122 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(525211..526122) Haemophilus influenzae Rd KW20 949923 NP_438668.1 CDS HI0510 NC_000907.1 526184 526903 D similar to GB:D15061 SP:P28634 PID:303558 GB:U00096 PID:1552771; hypothetical protein 526184..526903 Haemophilus influenzae Rd KW20 949577 NP_438669.1 CDS HI0511 NC_000907.1 526956 527942 R similar to GB:M74072 SP:P25396 PID:149017 GB:U00096 PID:1742325; potassium-tellurite ethidium and proflavin transporter complement(526956..527942) Haemophilus influenzae Rd KW20 950588 NP_438670.1 CDS hindIIR NC_000907.1 528159 528935 R HincIIR; HindIIR; binds gtyrac palindromes as a dimer; similar to GB:X52124 SP:P17743 PID:1573497; type II restriction endonuclease complement(528159..528935) Haemophilus influenzae Rd KW20 950710 NP_438671.1 CDS hindIIM NC_000907.1 528932 530488 R similar to SP:P17744; modification methylase complement(528932..530488) Haemophilus influenzae Rd KW20 950799 NP_438672.1 CDS rpoC NC_000907.1 530561 534808 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(530561..534808) Haemophilus influenzae Rd KW20 949579 NP_438673.1 CDS rpoB NC_000907.1 535050 539081 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(535050..539081) Haemophilus influenzae Rd KW20 949581 NP_438674.1 CDS rplA NC_000907.1 539465 540154 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(539465..540154) Haemophilus influenzae Rd KW20 949582 NP_438675.1 CDS rplK NC_000907.1 540159 540587 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(540159..540587) Haemophilus influenzae Rd KW20 949669 NP_438676.1 CDS deoD NC_000907.1 540760 541476 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(540760..541476) Haemophilus influenzae Rd KW20 949650 NP_438677.1 CDS HI0519 NC_000907.1 541560 542813 R similar to GB:AE000511 PID:2314337; transporter complement(541560..542813) Haemophilus influenzae Rd KW20 949656 NP_438678.1 CDS HI0520 NC_000907.1 542912 543700 R similar to GB:U14003 SP:P39409 PID:537219 GB:U00096 PID:1790839; hypothetical protein complement(542912..543700) Haemophilus influenzae Rd KW20 949583 NP_438679.1 CDS HI0521 NC_000907.1 543709 545253 R similar to GB:U14003 SP:P37342 PID:537220 GB:U00096 PID:1790840; hypothetical protein complement(543709..545253) Haemophilus influenzae Rd KW20 950665 NP_438680.1 CDS HI0522 NC_000907.1 545466 546122 D similar to GB:D26185 SP:P37505 PID:467358 GB:AL009126; hypothetical protein 545466..546122 Haemophilus influenzae Rd KW20 950631 NP_438681.2 CDS HI0523 NC_000907.1 546078 547118 R similar to GB:AE000511 PID:2314449; heptosyltransferase-like protein complement(546078..547118) Haemophilus influenzae Rd KW20 950662 NP_438682.1 CDS fba NC_000907.1 547186 548265 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(547186..548265) Haemophilus influenzae Rd KW20 949539 NP_438683.1 CDS pgk NC_000907.1 548376 549536 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(548376..549536) Haemophilus influenzae Rd KW20 949587 NP_438684.1 CDS HI0526 NC_000907.1 549638 550456 R hypothetical protein complement(549638..550456) Haemophilus influenzae Rd KW20 949589 NP_438685.1 CDS fdx-2 NC_000907.1 550534 550794 D similar to SP:P00208; ferredoxin 550534..550794 Haemophilus influenzae Rd KW20 949590 NP_438686.1 CDS tyrP NC_000907.1 550936 552156 R similar to GB:M23240 SP:P18199 PID:148089 GB:U00096 PID:1736569; tyrosine-specific transport protein complement(550936..552156) Haemophilus influenzae Rd KW20 949591 NP_438687.2 CDS tdk NC_000907.1 552193 552744 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(552193..552744) Haemophilus influenzae Rd KW20 949592 NP_438688.1 CDS gcp NC_000907.1 552783 553811 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(552783..553811) Haemophilus influenzae Rd KW20 950725 NP_438689.1 CDS rpsU NC_000907.1 554043 554258 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 554043..554258 Haemophilus influenzae Rd KW20 950699 NP_438690.1 CDS dnaG NC_000907.1 554392 556173 D synthesizes RNA primers at the replication forks; DNA primase 554392..556173 Haemophilus influenzae Rd KW20 949627 NP_438691.1 CDS rpoD NC_000907.1 556243 558132 D similar to GB:J01687 SP:P00579 PID:147756 PID:882590 PID:1072030; RNA polymerase sigma-70 factor 556243..558132 Haemophilus influenzae Rd KW20 949596 NP_438692.1 CDS aspA NC_000907.1 558436 559863 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(558436..559863) Haemophilus influenzae Rd KW20 949597 NP_438693.1 CDS ureH NC_000907.1 560041 560826 R similar to GB:M84338 SP:Q09067 PID:485336 PID:1247672 GB:AE000511; urease accessory protein complement(560041..560826) Haemophilus influenzae Rd KW20 949674 NP_438694.1 CDS ureG NC_000907.1 560901 561578 R similar to GB:M84338 SP:Q09066 PID:485335 PID:1247672 GB:AE000511; urease accessory protein complement(560901..561578) Haemophilus influenzae Rd KW20 950530 NP_438695.2 CDS ureF NC_000907.1 561681 562388 R similar to SP:Q07402 PID:393298; urease accessory protein UreF complement(561681..562388) Haemophilus influenzae Rd KW20 949598 NP_438696.1 CDS ureE NC_000907.1 562373 562930 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(562373..562930) Haemophilus influenzae Rd KW20 949599 NP_438697.1 CDS ureC NC_000907.1 563058 564776 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(563058..564776) Haemophilus influenzae Rd KW20 950768 NP_438698.1 CDS ureB NC_000907.1 564788 565093 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta complement(564788..565093) Haemophilus influenzae Rd KW20 950763 NP_438699.1 CDS ureA NC_000907.1 565169 565471 R UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma complement(565169..565471) Haemophilus influenzae Rd KW20 949600 NP_438700.1 CDS groES NC_000907.1 565634 565924 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 565634..565924 Haemophilus influenzae Rd KW20 949601 NP_438701.1 CDS groEL NC_000907.1 565947 567593 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 565947..567593 Haemophilus influenzae Rd KW20 950072 NP_438702.1 CDS rplI NC_000907.1 567767 568216 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(567767..568216) Haemophilus influenzae Rd KW20 950774 NP_438703.1 CDS rpsR NC_000907.1 568233 568460 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(568233..568460) Haemophilus influenzae Rd KW20 950770 NP_438704.2 CDS HI0546 NC_000907.1 568473 568799 R binds single-stranded DNA at the primosome assembly site; primosomal replication protein N complement(568473..568799) Haemophilus influenzae Rd KW20 949533 NP_438705.1 CDS rpsF NC_000907.1 568786 569163 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(568786..569163) Haemophilus influenzae Rd KW20 949602 NP_438706.2 CDS infA NC_000907.1 569362 569580 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(569362..569580) Haemophilus influenzae Rd KW20 949386 NP_438707.1 CDS ksgA NC_000907.1 569786 570649 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 569786..570649 Haemophilus influenzae Rd KW20 949586 NP_438708.1 CDS HI0550 NC_000907.1 570690 571598 R similar to GB:X56903 GB:L19441; lipooligosaccharide biosynthesis protein complement(570690..571598) Haemophilus influenzae Rd KW20 949673 NP_438709.1 CDS apaH NC_000907.1 571717 572544 D hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 571717..572544 Haemophilus influenzae Rd KW20 950805 NP_438710.1 CDS HI0552 NC_000907.1 572554 573177 D hypothetical protein 572554..573177 Haemophilus influenzae Rd KW20 949603 NP_438711.1 CDS gnd NC_000907.1 573303 574757 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(573303..574757) Haemophilus influenzae Rd KW20 949604 NP_438712.1 CDS HI0554 NC_000907.1 575203 575745 R hypothetical protein complement(575203..575745) Haemophilus influenzae Rd KW20 949606 NP_438713.1 CDS HI0555 NC_000907.1 575870 576109 R similar to GB:M87483 SP:Q02009 PID:551879; hypothetical protein complement(575870..576109) Haemophilus influenzae Rd KW20 950248 NP_438715.1 CDS zwf NC_000907.1 576891 578375 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(576891..578375) Haemophilus influenzae Rd KW20 949608 NP_438716.1 CDS cysQ NC_000907.1 578451 579137 R similar to SP:P22255 GB:M55170 GB:M80795 PID:145275 PID:145690; sulfite synthesis pathway protein complement(578451..579137) Haemophilus influenzae Rd KW20 949609 NP_438717.1 CDS HI0559.1 NC_000907.1 579332 579679 R hypothetical protein complement(579332..579679) Haemophilus influenzae Rd KW20 949585 NP_438718.1 CDS HI0561 NC_000907.1 579736 581637 R similar to PID:1655665; hypothetical protein complement(579736..581637) Haemophilus influenzae Rd KW20 950224 NP_438719.1 CDS HI0562 NC_000907.1 581951 582346 D similar to SP:P45802 PID:606334 GB:U00096 PID:1789803; hypothetical protein 581951..582346 Haemophilus influenzae Rd KW20 949610 NP_438720.1 CDS asnC NC_000907.1 582372 582824 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(582372..582824) Haemophilus influenzae Rd KW20 950765 NP_438721.1 CDS asnA NC_000907.1 582978 583970 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 582978..583970 Haemophilus influenzae Rd KW20 949631 NP_438722.1 CDS gph NC_000907.1 584035 584709 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(584035..584709) Haemophilus influenzae Rd KW20 949611 NP_438723.2 CDS dod NC_000907.1 584755 585429 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(584755..585429) Haemophilus influenzae Rd KW20 949612 NP_438724.1 CDS gyrB NC_000907.1 585576 587996 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(585576..587996) Haemophilus influenzae Rd KW20 949613 NP_438725.1 CDS tex NC_000907.1 588147 590435 R similar to SP:Q45388 PID:1477402; transcription accessory protein complement(588147..590435) Haemophilus influenzae Rd KW20 949614 NP_438726.1 CDS greB NC_000907.1 590531 591007 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 590531..591007 Haemophilus influenzae Rd KW20 950647 NP_438727.1 CDS HI0570 NC_000907.1 591078 591695 R negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR complement(591078..591695) Haemophilus influenzae Rd KW20 949502 NP_438728.1 CDS oxyR NC_000907.1 591695 592600 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(591695..592600) Haemophilus influenzae Rd KW20 950698 NP_438729.1 CDS HI0572 NC_000907.1 592723 593448 D contains peroxiredoxin and glutaredoxin domains; forms homotetramers; similar to PID:1652858; peroxiredoxin hybrid Prx5 592723..593448 Haemophilus influenzae Rd KW20 950101 NP_438730.1 CDS slyX NC_000907.1 593536 593757 R similar to GB:L13261 SP:P30857 PID:290468 PID:606282 GB:U00096; hypothetical protein complement(593536..593757) Haemophilus influenzae Rd KW20 949619 NP_438731.1 CDS fkpA NC_000907.1 593855 594580 D similar to SP:P45523 SP:P45527 PID:606281 PID:862300 GB:U00096; FKBP-type peptidyl-prolyl cis-trans isomerase 593855..594580 Haemophilus influenzae Rd KW20 949620 NP_438732.1 CDS HI0575 NC_000907.1 594669 595334 D similar to SP:P45533 PID:606280 GB:U00096 PID:1789744; hypothetical protein 594669..595334 Haemophilus influenzae Rd KW20 950683 NP_438733.1 CDS HI0576 NC_000907.1 595334 595714 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 595334..595714 Haemophilus influenzae Rd KW20 950688 NP_438734.1 CDS HI0576.1 NC_000907.1 595711 596070 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 595711..596070 Haemophilus influenzae Rd KW20 950759 NP_438735.1 CDS HI0577 NC_000907.1 596079 596366 D hypothetical protein 596079..596366 Haemophilus influenzae Rd KW20 949622 NP_438736.1 CDS tuf NC_000907.1 596497 597681 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(596497..597681) Haemophilus influenzae Rd KW20 949623 NP_438737.1 CDS fusA NC_000907.1 597746 599848 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(597746..599848) Haemophilus influenzae Rd KW20 950282 NP_438738.1 CDS rpS7 NC_000907.1 599932 600402 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(599932..600402) Haemophilus influenzae Rd KW20 949475 NP_438739.1 CDS rpsL NC_000907.1 600559 600933 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(600559..600933) Haemophilus influenzae Rd KW20 949625 NP_438740.1 CDS gidA NC_000907.1 601115 603004 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(601115..603004) Haemophilus influenzae Rd KW20 950589 NP_438741.1 CDS cpdB NC_000907.1 603690 605663 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase complement(603690..605663) Haemophilus influenzae Rd KW20 949588 NP_438742.1 CDS HI0584 NC_000907.1 605757 607028 R similar to GB:U00096 SP:P77357 PID:1742205 PID:1742209 PID:1787599; hydrolase complement(605757..607028) Haemophilus influenzae Rd KW20 950603 NP_438745.2 CDS pepE NC_000907.1 608461 609117 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(608461..609117) Haemophilus influenzae Rd KW20 949646 NP_438746.1 CDS HI0588 NC_000907.1 609241 610476 D allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 609241..610476 Haemophilus influenzae Rd KW20 950643 NP_438747.1 CDS HI0589 NC_000907.1 610691 611110 D similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096; sigma factor regulatory protein 610691..611110 Haemophilus influenzae Rd KW20 949630 NP_438748.1 CDS potE NC_000907.1 611212 612519 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(611212..612519) Haemophilus influenzae Rd KW20 950609 NP_438749.1 CDS speF NC_000907.1 612624 614786 R similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300; ornithine decarboxylase complement(612624..614786) Haemophilus influenzae Rd KW20 949823 NP_438751.1 CDS HI0594 NC_000907.1 615772 617301 R similar to GB:AE000783; hypothetical protein complement(615772..617301) Haemophilus influenzae Rd KW20 949632 NP_438752.1 CDS arcC NC_000907.1 617406 618338 R reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(617406..618338) Haemophilus influenzae Rd KW20 949637 NP_438753.1 CDS arcB NC_000907.1 618348 619352 R similar to GB:X05637 SP:P08308 PID:45288; ornithine carbamoyltransferase complement(618348..619352) Haemophilus influenzae Rd KW20 950778 NP_438754.1 CDS HI0597 NC_000907.1 619754 620572 D similar to SP:P27848; hypothetical protein 619754..620572 Haemophilus influenzae Rd KW20 950123 NP_438755.1 CDS ccrB NC_000907.1 620572 621054 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 620572..621054 Haemophilus influenzae Rd KW20 949807 NP_438756.2 CDS recX NC_000907.1 620954 621412 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(620954..621412) Haemophilus influenzae Rd KW20 949641 NP_438757.1 CDS recA NC_000907.1 621492 622556 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(621492..622556) Haemophilus influenzae Rd KW20 949644 NP_438758.1 CDS tfoX NC_000907.1 622876 623529 D similar to GB:U13205 PID:1573592; DNA transformation protein 622876..623529 Haemophilus influenzae Rd KW20 949645 NP_438760.1 CDS hemY NC_000907.1 630346 631632 R similar to GB:M87049 SP:P09128 GB:X12614 PID:148201 PID:41669; protoheme synthesis protein HemY complement(630346..631632) Haemophilus influenzae Rd KW20 949653 NP_438761.2 CDS hemX NC_000907.1 631643 632856 R heme biosynthesis-like protein complement(join(631643..632173,632173..632856)) Haemophilus influenzae Rd KW20 949795 NP_438762.1 CDS cyaA NC_000907.1 633161 635692 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 633161..635692 Haemophilus influenzae Rd KW20 950010 NP_438763.1 CDS gpsA NC_000907.1 635766 636773 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 635766..636773 Haemophilus influenzae Rd KW20 949436 NP_438764.1 CDS cysE NC_000907.1 636785 637588 D catalyzes the O-acetylation of serine; serine acetyltransferase 636785..637588 Haemophilus influenzae Rd KW20 949654 NP_438765.1 CDS aroE NC_000907.1 637598 638413 D catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 637598..638413 Haemophilus influenzae Rd KW20 949659 NP_438766.1 CDS HI0608 NC_000907.1 638552 639937 D similar to GB:L77117 SP:Q58086 PID:1591386; di- and tricarboxylate transporter 638552..639937 Haemophilus influenzae Rd KW20 949996 NP_438767.1 CDS folD NC_000907.1 640075 640923 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(640075..640923) Haemophilus influenzae Rd KW20 950705 NP_438768.1 CDS fucP NC_000907.1 641451 642737 R similar to SP:P11551 GB:X15025 PID:146041 PID:41504 PID:882696; L-fucose permease complement(641451..642737) Haemophilus influenzae Rd KW20 950599 NP_438769.1 CDS fucA NC_000907.1 642776 643426 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(642776..643426) Haemophilus influenzae Rd KW20 950000 NP_438770.1 CDS fucU NC_000907.1 643446 643880 R similar to PID:882699 GB:U00096 PID:1789169; fucose operon protein complement(643446..643880) Haemophilus influenzae Rd KW20 949663 NP_438771.1 CDS fucK NC_000907.1 643894 645306 R similar to SP:P11553 GB:X15025 PID:41506 PID:882698 GB:U00096; L-fuculokinase complement(643894..645306) Haemophilus influenzae Rd KW20 950556 NP_438772.2 CDS fucI NC_000907.1 645379 647148 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(645379..647148) Haemophilus influenzae Rd KW20 950887 NP_438773.1 CDS fucR NC_000907.1 647375 648124 R similar to SP:P11554 GB:X15025 PID:41508 PID:882700 GB:U00096; L-fucose operon activator complement(647375..648124) Haemophilus influenzae Rd KW20 949664 NP_438774.1 CDS hepA NC_000907.1 648322 651093 D transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 648322..651093 Haemophilus influenzae Rd KW20 949665 NP_438775.1 CDS HI0617 NC_000907.1 651096 651755 D similar to SP:P39219 GB:U00096 PID:1786244; hypothetical protein 651096..651755 Haemophilus influenzae Rd KW20 950684 NP_438776.1 CDS HI0618 NC_000907.1 651782 652360 D similar to GB:M54940 SP:P09391 GB:M96795 PID:146185 PID:146193; glp protein 651782..652360 Haemophilus influenzae Rd KW20 950685 NP_438777.1 CDS glpR NC_000907.1 652390 653157 D similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096; glycerol-3-phosphate regulon repressor 652390..653157 Haemophilus influenzae Rd KW20 950682 NP_438778.1 CDS hlpA NC_000907.1 653459 654280 R similar to GB:M59804 SP:P31728 PID:1573614; D-methionine-binding lipoprotein MetQ complement(653459..654280) Haemophilus influenzae Rd KW20 950676 NP_438780.1 CDS metN NC_000907.1 654999 656036 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding protein complement(654999..656036) Haemophilus influenzae Rd KW20 950557 NP_438781.1 CDS HI0621.1 NC_000907.1 656212 656766 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 656212..656766 Haemophilus influenzae Rd KW20 949688 NP_438782.1 CDS def NC_000907.1 662609 663118 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 662609..663118 Haemophilus influenzae Rd KW20 949678 NP_438783.1 CDS fmt NC_000907.1 663211 664167 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 663211..664167 Haemophilus influenzae Rd KW20 949680 NP_438784.1 CDS sun NC_000907.1 664167 665522 D similar to SP:P36929 SP:P36929 GB:X52114 PID:43136 PID:443992; sun protein 664167..665522 Haemophilus influenzae Rd KW20 949681 NP_438785.1 CDS trkA NC_000907.1 665535 666911 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 665535..666911 Haemophilus influenzae Rd KW20 949682 NP_438786.1 CDS mscL NC_000907.1 666984 667370 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 666984..667370 Haemophilus influenzae Rd KW20 950793 NP_438787.1 CDS HI0627 NC_000907.1 667460 667717 D similar to PID:887847 GB:U00096 SP:Q46825 PID:1789264; hypothetical protein 667460..667717 Haemophilus influenzae Rd KW20 950813 NP_438788.1 CDS rpoE NC_000907.1 667825 668394 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 667825..668394 Haemophilus influenzae Rd KW20 950801 NP_438789.1 CDS mclA NC_000907.1 668419 669006 D similar to SP:P38106 GB:U10148 GB:U00096 PID:1788925 PID:987647; sigma-E factor negative regulatory protein 668419..669006 Haemophilus influenzae Rd KW20 949684 NP_438790.1 CDS rseB NC_000907.1 669086 670033 D periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; negative regulator of sigmaE 669086..670033 Haemophilus influenzae Rd KW20 949706 NP_438791.1 CDS coaA NC_000907.1 670124 671059 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(670124..671059) Haemophilus influenzae Rd KW20 949538 NP_438792.1 CDS tuf NC_000907.1 671764 672948 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 671764..672948 Haemophilus influenzae Rd KW20 950329 NP_438793.2 CDS HI0633 NC_000907.1 673116 673493 D hypothetical protein 673116..673493 Haemophilus influenzae Rd KW20 950781 NP_438794.1 CDS HI0634 NC_000907.1 673496 674479 D similar to SP:P32695 PID:396384 GB:U00096 PID:1790483; tRNA-dihydrouridine synthase A 673496..674479 Haemophilus influenzae Rd KW20 950134 NP_438795.2 CDS HI0635 NC_000907.1 674692 677850 R similar to PID:1000292 PID:984513; hemoglobin-binding protein complement(674692..677850) Haemophilus influenzae Rd KW20 950591 NP_438796.1 CDS HI0636 NC_000907.1 678239 678529 R similar to GB:U00096 PID:1788685; hypothetical protein complement(678239..678529) Haemophilus influenzae Rd KW20 949687 NP_438797.1 CDS trpS NC_000907.1 678551 679555 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(678551..679555) Haemophilus influenzae Rd KW20 949689 NP_438798.1 CDS HI0638 NC_000907.1 679684 680301 D HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 679684..680301 Haemophilus influenzae Rd KW20 950538 NP_438799.1 CDS purB NC_000907.1 680324 681694 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 680324..681694 Haemophilus influenzae Rd KW20 949686 NP_438800.1 CDS rplJ NC_000907.1 681966 682457 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 681966..682457 Haemophilus influenzae Rd KW20 950716 NP_438801.1 CDS rplL NC_000907.1 682512 682883 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 682512..682883 Haemophilus influenzae Rd KW20 949690 NP_438802.1 CDS glmU NC_000907.1 683043 684413 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 683043..684413 Haemophilus influenzae Rd KW20 949691 YP_008530233.1 CDS HI0642a NC_000907.1 684452 684763 R hypothetical protein complement(684452..684763) Haemophilus influenzae Rd KW20 16830694 NP_438803.1 CDS bisC NC_000907.1 685466 687943 R similar to SP:P46923 PID:1045667 GB:U00096 PID:1736518 PID:1736526; biotin sulfoxide reductase complement(685466..687943) Haemophilus influenzae Rd KW20 950790 NP_438804.2 CDS yecK NC_000907.1 687976 689076 R similar to SP:P52005 GB:U00096 PID:1736519 PID:1736527 PID:1788181; cytochrome C-like protein complement(687976..689076) Haemophilus influenzae Rd KW20 950598 NP_438805.1 CDS pldB NC_000907.1 689231 690172 R similar to PID:1449198; lysophospholipase L2 complement(689231..690172) Haemophilus influenzae Rd KW20 949694 NP_438806.1 CDS asd NC_000907.1 690227 691342 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(690227..691342) Haemophilus influenzae Rd KW20 949960 NP_438807.1 CDS HI0647 NC_000907.1 691501 692217 R similar to GB:M57715 SP:P22037 PID:154179; transporter complement(691501..692217) Haemophilus influenzae Rd KW20 949408 NP_438808.2 CDS mdaB NC_000907.1 692495 693073 R similar to SP:P40717 PID:609328 PID:882558 GB:U00096 PID:1789406; modulator of drug activity B complement(692495..693073) Haemophilus influenzae Rd KW20 949679 NP_438809.1 CDS rep NC_000907.1 693363 695375 R similar to GB:M87049 SP:P09980 GB:X04794 PID:148182 GB:U00096; ATP-dependent DNA helicase complement(693363..695375) Haemophilus influenzae Rd KW20 949695 NP_438810.1 CDS HI0650 NC_000907.1 695381 695593 R hypothetical protein complement(695381..695593) Haemophilus influenzae Rd KW20 949696 NP_438811.1 CDS coaD NC_000907.1 695590 696060 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(695590..696060) Haemophilus influenzae Rd KW20 949693 NP_438812.1 CDS kdtA NC_000907.1 696057 697340 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(696057..697340) Haemophilus influenzae Rd KW20 949683 NP_438813.1 CDS HI0653 NC_000907.1 697403 698167 D similar to PID:1389735; lipopolysaccharide biosynthesis protein 697403..698167 Haemophilus influenzae Rd KW20 950619 NP_438814.1 CDS tagI NC_000907.1 698164 698721 R similar to SP:P05100 GB:J02606 GB:X03845 PID:147920 PID:43030; DNA-3-methyladenine glycosylase complement(698164..698721) Haemophilus influenzae Rd KW20 949931 NP_438815.1 CDS aroE NC_000907.1 698718 699536 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(698718..699536) Haemophilus influenzae Rd KW20 949697 NP_438816.1 CDS HI0656 NC_000907.1 699540 700091 R similar to SP:P45748 PID:606216 GB:U00096 PID:2367210; hypothetical protein complement(699540..700091) Haemophilus influenzae Rd KW20 950161 NP_438817.1 CDS HI0656.1 NC_000907.1 700107 700643 R similar to SP:P45771 PID:606217 GB:U00096 PID:1789677; hypothetical protein complement(700107..700643) Haemophilus influenzae Rd KW20 949423 NP_438818.1 CDS HI0658 NC_000907.1 700653 702569 R similar to SP:P45535 PID:606286 GB:U00096 PID:1789751; ABC transporter ATP-binding protein complement(700653..702569) Haemophilus influenzae Rd KW20 949699 NP_438819.1 CDS HI0659 NC_000907.1 702730 703026 R HTH-type transcriptional regulator complement(702730..703026) Haemophilus influenzae Rd KW20 949700 NP_438820.1 CDS HI0660 NC_000907.1 703019 703378 R hypothetical protein complement(703019..703378) Haemophilus influenzae Rd KW20 950644 NP_438821.1 CDS oapA NC_000907.1 703648 706680 R similar to PID:1000292 PID:984513; hemoglobin-binding protein complement(703648..706680) Haemophilus influenzae Rd KW20 949701 NP_438822.1 CDS cydD NC_000907.1 707165 708910 D ABC transporter ATP-binding protein 707165..708910 Haemophilus influenzae Rd KW20 949702 NP_438823.1 CDS HI0664 NC_000907.1 708903 710561 D similar to GB:AL009126; ABC transporter ATP-binding protein 708903..710561 Haemophilus influenzae Rd KW20 949703 NP_438824.1 CDS HI0665 NC_000907.1 710645 711676 R hypothetical protein complement(710645..711676) Haemophilus influenzae Rd KW20 949704 NP_438825.1 CDS HI0666 NC_000907.1 711673 711993 R hypothetical protein complement(711673..711993) Haemophilus influenzae Rd KW20 949708 NP_438826.1 CDS HI0666.1 NC_000907.1 711981 712289 R hypothetical protein complement(711981..712289) Haemophilus influenzae Rd KW20 949707 NP_438827.1 CDS glpX NC_000907.1 712489 713490 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(712489..713490) Haemophilus influenzae Rd KW20 949705 NP_438828.1 CDS HI0668 NC_000907.1 713652 713870 D similar to GB:L19201 SP:P32164 PID:305031 GB:U00096 PID:1790363; hypothetical protein 713652..713870 Haemophilus influenzae Rd KW20 949710 NP_438829.1 CDS mioC NC_000907.1 713967 714407 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 713967..714407 Haemophilus influenzae Rd KW20 949711 NP_438830.1 CDS HI0670 NC_000907.1 714404 714838 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 714404..714838 Haemophilus influenzae Rd KW20 949713 NP_438831.1 CDS ispF NC_000907.1 715140 715616 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(715140..715616) Haemophilus influenzae Rd KW20 950633 NP_438832.1 CDS ispD NC_000907.1 715613 716290 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(715613..716290) Haemophilus influenzae Rd KW20 950888 NP_438833.1 CDS ftsB NC_000907.1 716290 716568 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(716290..716568) Haemophilus influenzae Rd KW20 950558 NP_438834.1 CDS gptA NC_000907.1 716691 717158 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(716691..717158) Haemophilus influenzae Rd KW20 949714 NP_438835.1 CDS pepD NC_000907.1 717269 718723 D similar to GB:M34034 SP:P15288 GB:X14790 PID:1208983 PID:147140; aminoacyl-histidine dipeptidase 717269..718723 Haemophilus influenzae Rd KW20 950737 NP_438836.1 CDS xerC NC_000907.1 718776 719663 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(718776..719663) Haemophilus influenzae Rd KW20 950745 NP_438837.1 CDS HI0677 NC_000907.1 719657 720097 R hypothetical protein complement(719657..720097) Haemophilus influenzae Rd KW20 950735 NP_438838.1 CDS tpiA NC_000907.1 720263 721054 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 720263..721054 Haemophilus influenzae Rd KW20 950739 NP_438839.1 CDS glpE NC_000907.1 721137 721454 R similar to GB:X07520 SP:P09390 GB:M96795 PID:146184 PID:146192; thiosulfate sulfurtransferase GlpE complement(721137..721454) Haemophilus influenzae Rd KW20 949715 NP_438840.1 CDS HI0680 NC_000907.1 721436 722332 R similar to SP:P27844; RarD protein complement(721436..722332) Haemophilus influenzae Rd KW20 949717 NP_438841.1 CDS ilvY NC_000907.1 722364 723242 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(722364..723242) Haemophilus influenzae Rd KW20 949718 NP_438842.1 CDS ilvC NC_000907.1 723919 725397 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 723919..725397 Haemophilus influenzae Rd KW20 949478 NP_438843.1 CDS glpC NC_000907.1 725508 726788 R anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C complement(725508..726788) Haemophilus influenzae Rd KW20 949971 NP_438844.1 CDS glpB NC_000907.1 726800 728098 R sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(726800..728098) Haemophilus influenzae Rd KW20 950690 NP_438845.1 CDS glpA NC_000907.1 728088 729779 R anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A complement(728088..729779) Haemophilus influenzae Rd KW20 949605 NP_438846.1 CDS glpT NC_000907.1 730072 731514 D similar to SP:P08194 GB:Y00536 PID:41587 GB:U00096 PID:1788573; glycerol-3-phosphatase transporter 730072..731514 Haemophilus influenzae Rd KW20 949719 NP_438847.1 CDS HI0687 NC_000907.1 731614 732528 D similar to GB:D26185 SP:P37511 PID:467365 GB:AL009126; hypothetical protein 731614..732528 Haemophilus influenzae Rd KW20 949720 NP_438848.1 CDS HI0688 NC_000907.1 732623 732934 D hypothetical protein 732623..732934 Haemophilus influenzae Rd KW20 949721 NP_438849.1 CDS glpQ NC_000907.1 732946 734040 D hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 732946..734040 Haemophilus influenzae Rd KW20 949981 NP_438850.1 CDS glpF NC_000907.1 734270 735064 D similar to GB:L19201 SP:P11244 GB:M55990 GB:U13915 GB:X15054; glycerol uptake facilitator protein 734270..735064 Haemophilus influenzae Rd KW20 949956 NP_438851.1 CDS glpK NC_000907.1 735085 736596 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 735085..736596 Haemophilus influenzae Rd KW20 949976 NP_438852.1 CDS gptB NC_000907.1 736671 737138 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(736671..737138) Haemophilus influenzae Rd KW20 949722 NP_438853.1 CDS hel NC_000907.1 737422 738246 D similar to GB:M68502 SP:P26093 PID:1573696; lipoprotein E 737422..738246 Haemophilus influenzae Rd KW20 949723 NP_438854.1 CDS HI0694 NC_000907.1 738386 739108 D similar to GB:U00096 SP:P75966 PID:1787380; hypothetical protein 738386..739108 Haemophilus influenzae Rd KW20 950211 NP_438855.1 CDS HI0695 NC_000907.1 739234 740205 R similar to GB:L06129 SP:P29014 PID:147343 GB:U00096 PID:1788848; exopolyphosphatase complement(739234..740205) Haemophilus influenzae Rd KW20 950213 NP_438856.1 CDS HI0696 NC_000907.1 740213 744109 R similar to GB:U14003 SP:P39321 PID:537063 GB:U00096; hypothetical protein complement(740213..744109) Haemophilus influenzae Rd KW20 950032 NP_438857.1 CDS HI0698 NC_000907.1 744119 745855 R similar to GB:U14003 SP:P39320 PID:537061 GB:U00096 PID:1790666; hypothetical protein complement(744119..745855) Haemophilus influenzae Rd KW20 950204 NP_438858.1 CDS slyD NC_000907.1 746006 746578 R similar to GB:L13261 SP:P30856 GB:Z21496 PID:394720 PID:475995; peptidyl-prolyl cis-trans isomerase complement(746006..746578) Haemophilus influenzae Rd KW20 949724 NP_438859.1 CDS HI0700 NC_000907.1 746658 747119 R similar to SP:P37163 GB:U14003 PID:537096 GB:U00096 PID:1790704; hypothetical protein complement(746658..747119) Haemophilus influenzae Rd KW20 949725 NP_438860.1 CDS truD NC_000907.1 747228 748247 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 747228..748247 Haemophilus influenzae Rd KW20 949727 NP_438861.1 CDS surE NC_000907.1 748257 749006 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 748257..749006 Haemophilus influenzae Rd KW20 949728 NP_438862.1 CDS lppB NC_000907.1 749015 749593 D similar to GB:L10653 SP:P36684 PID:148929; lipoprotein B 749015..749593 Haemophilus influenzae Rd KW20 949729 NP_438863.1 CDS HI0704 NC_000907.1 749602 749787 D hypothetical protein 749602..749787 Haemophilus influenzae Rd KW20 949730 NP_438864.1 CDS HI0706 NC_000907.1 749811 751028 D similar to GB:L07869 SP:P33648 PID:404099 PID:433185 PID:882635; lipoprotein 749811..751028 Haemophilus influenzae Rd KW20 949731 NP_438865.1 CDS mutS NC_000907.1 751161 753746 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 751161..753746 Haemophilus influenzae Rd KW20 949732 NP_438866.1 CDS selA NC_000907.1 753952 755337 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 753952..755337 Haemophilus influenzae Rd KW20 950262 NP_438867.1 CDS selB NC_000907.1 755334 757193 D similar to SP:P14081 GB:X16644 PID:42937 PID:466728 GB:U00096; selenocysteine-specific elongation factor 755334..757193 Haemophilus influenzae Rd KW20 950261 NP_438868.1 CDS HI0710 NC_000907.1 757421 757717 D hypothetical protein 757421..757717 Haemophilus influenzae Rd KW20 950711 NP_438869.1 CDS HI0711 NC_000907.1 757717 758025 D similar to PID:984581 GB:U00096 SP:Q47149 PID:1786419; hypothetical protein 757717..758025 Haemophilus influenzae Rd KW20 949734 NP_438870.1 CDS HI0712 NC_000907.1 758082 761336 R similar to PID:1000292 PID:984513; hemoglobin-binding protein complement(758082..761336) Haemophilus influenzae Rd KW20 949735 NP_438871.1 CDS tig NC_000907.1 761637 762935 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 761637..762935 Haemophilus influenzae Rd KW20 949736 NP_438872.3 CDS clpP NC_000907.1 763058 763639 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 763058..763639 Haemophilus influenzae Rd KW20 949737 NP_438873.1 CDS clpX NC_000907.1 763649 764884 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 763649..764884 Haemophilus influenzae Rd KW20 949862 NP_438874.1 CDS secE NC_000907.1 765122 765442 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 765122..765442 Haemophilus influenzae Rd KW20 949943 NP_438875.1 CDS nusG NC_000907.1 765444 766001 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 765444..766001 Haemophilus influenzae Rd KW20 950637 NP_438876.1 CDS vacJ NC_000907.1 766152 766904 D similar to SP:P43262 PID:904221; lipoprotein 766152..766904 Haemophilus influenzae Rd KW20 949738 NP_438877.1 CDS HI0719 NC_000907.1 766958 767350 D unknown function; forms homotrimers; binds small molecules of alpha-keto acids or alpha,beta-unsaturated acids; similar to GB:U14003 SP:P39330 PID:537085 GB:U00096 PID:1790691; hypothetical protein 766958..767350 Haemophilus influenzae Rd KW20 949739 NP_438878.1 CDS htpX NC_000907.1 767518 768369 D metalloprotease; heat shock protein HtpX 767518..768369 Haemophilus influenzae Rd KW20 949740 NP_438879.2 CDS HI0721 NC_000907.1 768411 768650 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(768411..768650) Haemophilus influenzae Rd KW20 949741 NP_438880.2 CDS HI0722 NC_000907.1 768754 769386 D similar to GB:U00096 PID:1790283; hypothetical protein 768754..769386 Haemophilus influenzae Rd KW20 949742 NP_438881.1 CDS trkH NC_000907.1 769389 770852 D similar to GB:M87049 SP:P21166 PID:148249 PID:42359 PID:2367317; Trk system potassium uptake protein TrkH 769389..770852 Haemophilus influenzae Rd KW20 949570 NP_438882.1 CDS HI0724 NC_000907.1 776909 777469 D similar to PID:1685095; hypothetical protein 776909..777469 Haemophilus influenzae Rd KW20 949751 NP_438883.1 CDS HI0725 NC_000907.1 777473 777913 D similar to PID:1685094; hypothetical protein 777473..777913 Haemophilus influenzae Rd KW20 949753 NP_438884.1 CDS narP NC_000907.1 777975 778601 R similar to GB:U00008 SP:P31802 GB:L11273 PID:304917 PID:405947; nitrate/nitrite response regulator protein complement(777975..778601) Haemophilus influenzae Rd KW20 949754 NP_438885.1 CDS lysA NC_000907.1 778807 780054 R similar to SP:P19572; diaminopimelate decarboxylase complement(778807..780054) Haemophilus influenzae Rd KW20 949755 NP_438886.1 CDS cyaY NC_000907.1 780315 780620 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 780315..780620 Haemophilus influenzae Rd KW20 949756 NP_438887.1 CDS recQ NC_000907.1 780622 782481 D similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221; ATP-dependent DNA helicase 780622..782481 Haemophilus influenzae Rd KW20 949757 NP_438888.1 CDS proS NC_000907.1 782566 784284 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 782566..784284 Haemophilus influenzae Rd KW20 949758 NP_438889.1 CDS HI0730 NC_000907.1 784372 786720 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(784372..786720) Haemophilus influenzae Rd KW20 949761 NP_438893.1 CDS plsC NC_000907.1 788247 788969 R similar to GB:M63491 SP:P26647 PID:147298 PID:882548 GB:U00096; 1-acylglycerol-3-phosphate O-acyltransferase complement(788247..788969) Haemophilus influenzae Rd KW20 950749 NP_438894.1 CDS HI0735 NC_000907.1 789055 789768 D catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 789055..789768 Haemophilus influenzae Rd KW20 950740 NP_438895.1 CDS HI0736 NC_000907.1 789998 791524 R similar to GB:AE000782; sodium-dependent transporter complement(789998..791524) Haemophilus influenzae Rd KW20 949764 NP_438896.1 CDS HI0737 NC_000907.1 791772 792569 D similar to GB:M10313 SP:P00892 GB:M32253 GB:V00290 GB:X04890; acetohydroxy acid synthase II 791772..792569 Haemophilus influenzae Rd KW20 949765 NP_438897.1 CDS ilvD NC_000907.1 792641 794479 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 792641..794479 Haemophilus influenzae Rd KW20 949825 NP_438898.1 CDS ilvA NC_000907.1 794559 796100 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 794559..796100 Haemophilus influenzae Rd KW20 950764 NP_438899.1 CDS dnaE NC_000907.1 796139 799618 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(796139..799618) Haemophilus influenzae Rd KW20 949766 NP_438900.2 CDS yhxB NC_000907.1 799857 801509 D similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126; phosphomannomutase 799857..801509 Haemophilus influenzae Rd KW20 949768 NP_438901.1 CDS HI0742 NC_000907.1 801658 801987 D hypothetical protein 801658..801987 Haemophilus influenzae Rd KW20 949769 NP_438902.1 CDS secB NC_000907.1 802054 802563 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(802054..802563) Haemophilus influenzae Rd KW20 949770 NP_438903.1 CDS HI0744 NC_000907.1 802577 803023 R similar to SP:P37688 PID:466749 GB:U00096 PID:1790040; hypothetical protein complement(802577..803023) Haemophilus influenzae Rd KW20 949771 NP_438904.1 CDS ansB NC_000907.1 803249 804298 D catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 803249..804298 Haemophilus influenzae Rd KW20 949675 NP_438905.1 CDS dcuB NC_000907.1 804454 805776 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 804454..805776 Haemophilus influenzae Rd KW20 950696 NP_438906.1 CDS ndh NC_000907.1 805980 807314 D similar to SP:P00393 PID:581140 GB:U00096 PID:1651546 PID:1787352; NADH dehydrogenase 805980..807314 Haemophilus influenzae Rd KW20 949772 NP_438907.1 CDS HI0748 NC_000907.1 807394 809826 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(807394..809826) Haemophilus influenzae Rd KW20 949773 NP_438908.2 CDS lexA NC_000907.1 810081 810704 D Represses a number of genes involved in the response to DNA damage; LexA repressor 810081..810704 Haemophilus influenzae Rd KW20 949794 NP_438909.1 CDS dapF NC_000907.1 810848 811672 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 810848..811672 Haemophilus influenzae Rd KW20 949560 NP_438910.1 CDS tpx NC_000907.1 811891 812388 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(811891..812388) Haemophilus influenzae Rd KW20 949774 NP_438911.1 CDS purL NC_000907.1 812967 816929 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 812967..816929 Haemophilus influenzae Rd KW20 949775 NP_438912.1 CDS anmK NC_000907.1 817101 818249 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 817101..818249 Haemophilus influenzae Rd KW20 949467 NP_438913.1 CDS murQ NC_000907.1 818259 819170 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 818259..819170 Haemophilus influenzae Rd KW20 949804 NP_438914.2 CDS dat1 NC_000907.1 819200 820042 R similar to SP:P37691 PID:912478 GB:U00096 PID:1790043; hypothetical protein complement(819200..820042) Haemophilus influenzae Rd KW20 949515 NP_438915.1 CDS HI0756 NC_000907.1 820042 821274 R similar to SP:P37690 PID:466751 GB:U00096 PID:1790042; hypothetical protein complement(820042..821274) Haemophilus influenzae Rd KW20 950697 NP_438916.1 CDS gpmA NC_000907.1 821450 822133 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 821450..822133 Haemophilus influenzae Rd KW20 949776 NP_438917.1 CDS rpmE NC_000907.1 822211 822423 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(822211..822423) Haemophilus influenzae Rd KW20 950704 NP_438918.1 CDS mutY NC_000907.1 822600 823736 D similar to GB:M59471 SP:P17802 GB:X52391 PID:146864 PID:42073; A/G-specific adenine glycosylase 822600..823736 Haemophilus influenzae Rd KW20 950824 NP_438919.1 CDS HI0760 NC_000907.1 823714 823986 D similar to PID:882491 SP:P52065 GB:U00096 PID:1789332; hypothetical protein 823714..823986 Haemophilus influenzae Rd KW20 949979 NP_438920.1 CDS mltC NC_000907.1 824001 825074 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 824001..825074 Haemophilus influenzae Rd KW20 950821 NP_438921.1 CDS HI0762 NC_000907.1 825685 826365 R hypothetical protein complement(825685..826365) Haemophilus influenzae Rd KW20 949781 NP_438922.1 CDS nadR NC_000907.1 826362 827627 R catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase complement(826362..827627) Haemophilus influenzae Rd KW20 950800 NP_438923.1 CDS ribB NC_000907.1 827846 828493 D DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 827846..828493 Haemophilus influenzae Rd KW20 950808 NP_438924.2 CDS HI0765 NC_000907.1 828520 829356 D similar to GB:M37913 GB:L19441 PID:1573535; lipooligosaccharide biosynthesis protein 828520..829356 Haemophilus influenzae Rd KW20 950810 NP_438925.1 CDS yibK NC_000907.1 829405 829887 R YibK; binds cofactor S-adenosylhomocysteine; similar to SP:P33899 PID:466744 GB:U00096 PID:1790034; RNA methyltransferase complement(829405..829887) Haemophilus influenzae Rd KW20 949782 NP_438926.1 CDS HI0767 NC_000907.1 829898 830479 R similar to SP:P10120 GB:U00039 GB:X04398 PID:41497 PID:466601; hypothetical protein complement(829898..830479) Haemophilus influenzae Rd KW20 949786 NP_438927.1 CDS ftsY NC_000907.1 830534 831778 D similar to SP:P10121 GB:U00039 GB:X04398 PID:41498 PID:466600; cell division protein FtsY 830534..831778 Haemophilus influenzae Rd KW20 950144 NP_438928.1 CDS ftsE NC_000907.1 831797 832453 D similar to SP:P10115 GB:U00039 GB:X04398 PID:41499 PID:466599; cell division ATP-binding protein 831797..832453 Haemophilus influenzae Rd KW20 950167 NP_438929.1 CDS ftsX NC_000907.1 832463 833395 D ABC transporter, membrane protein; cell division protein FtsX 832463..833395 Haemophilus influenzae Rd KW20 949837 NP_438930.1 CDS atoB NC_000907.1 833490 834671 R similar to GB:U00096 SP:P76461 PID:1736879 PID:1788554 PID:1799573; acetyl-CoA acetyltransferase complement(833490..834671) Haemophilus influenzae Rd KW20 950638 NP_438931.1 CDS atoE NC_000907.1 834686 836029 R similar to GB:U00096 SP:P76460 PID:1788553; short chain fatty acids transporter complement(834686..836029) Haemophilus influenzae Rd KW20 949788 NP_438932.1 CDS atoA NC_000907.1 836026 836697 R similar to GB:U00096 SP:P76459 PID:1736877 PID:1788552; acetate CoA-transferase subunit beta complement(836026..836697) Haemophilus influenzae Rd KW20 949789 NP_438933.1 CDS HI0774 NC_000907.1 836708 837361 R similar to GB:U00096 SP:P76458 PID:1736876 PID:1788551; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha complement(836708..837361) Haemophilus influenzae Rd KW20 949792 NP_438934.2 CDS HI0775 NC_000907.1 837609 838514 D similar to GB:X73124 SP:P39592 PID:413948 GB:AL009126; transcriptional regulator 837609..838514 Haemophilus influenzae Rd KW20 950670 NP_438935.2 CDS rpsJ NC_000907.1 838750 839061 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 838750..839061 Haemophilus influenzae Rd KW20 950681 NP_438936.1 CDS rplC NC_000907.1 839078 839704 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 839078..839704 Haemophilus influenzae Rd KW20 950820 NP_438937.1 CDS rplD NC_000907.1 839720 840322 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 839720..840322 Haemophilus influenzae Rd KW20 950806 NP_438938.1 CDS rplW NC_000907.1 840319 840618 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 840319..840618 Haemophilus influenzae Rd KW20 949793 NP_438939.1 CDS rplB NC_000907.1 840636 841457 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 840636..841457 Haemophilus influenzae Rd KW20 949796 NP_438940.1 CDS rpsS NC_000907.1 841483 841758 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 841483..841758 Haemophilus influenzae Rd KW20 949797 NP_438941.1 CDS rplV NC_000907.1 841770 842102 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 841770..842102 Haemophilus influenzae Rd KW20 949798 NP_438942.1 CDS rpsC NC_000907.1 842120 842827 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 842120..842827 Haemophilus influenzae Rd KW20 949799 NP_438943.1 CDS rplP NC_000907.1 842841 843251 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 842841..843251 Haemophilus influenzae Rd KW20 950752 NP_438944.1 CDS rpmC NC_000907.1 843251 843442 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 843251..843442 Haemophilus influenzae Rd KW20 950743 NP_438945.1 CDS rpsQ NC_000907.1 843442 843699 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 843442..843699 Haemophilus influenzae Rd KW20 949800 NP_438946.1 CDS HI0787 NC_000907.1 844090 844695 D hypothetical protein 844090..844695 Haemophilus influenzae Rd KW20 949801 NP_438947.1 CDS rplN NC_000907.1 844976 845347 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 844976..845347 Haemophilus influenzae Rd KW20 949802 NP_438948.1 CDS rplX NC_000907.1 845358 845669 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 845358..845669 Haemophilus influenzae Rd KW20 949805 NP_438949.3 CDS rplE NC_000907.1 845687 846226 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 845687..846226 Haemophilus influenzae Rd KW20 949806 NP_438950.1 CDS rpsN NC_000907.1 846238 846543 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 846238..846543 Haemophilus influenzae Rd KW20 949808 NP_438951.1 CDS rpsH NC_000907.1 846580 846972 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 846580..846972 Haemophilus influenzae Rd KW20 949811 NP_438952.1 CDS rplF NC_000907.1 846988 847521 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 846988..847521 Haemophilus influenzae Rd KW20 950560 NP_438953.1 CDS rplR NC_000907.1 847535 847888 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 847535..847888 Haemophilus influenzae Rd KW20 950639 NP_438954.1 CDS rpsE NC_000907.1 847903 848403 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 847903..848403 Haemophilus influenzae Rd KW20 949813 NP_438955.1 CDS rpmD NC_000907.1 848410 848589 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 848410..848589 Haemophilus influenzae Rd KW20 949787 NP_438956.1 CDS rplO NC_000907.1 848593 849027 D late assembly protein; 50S ribosomal protein L15 848593..849027 Haemophilus influenzae Rd KW20 949815 NP_438957.1 CDS secY NC_000907.1 849035 850360 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 849035..850360 Haemophilus influenzae Rd KW20 949574 NP_438958.1 CDS rpmJ NC_000907.1 850389 850502 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 850389..850502 Haemophilus influenzae Rd KW20 949814 NP_438959.3 CDS rpsM NC_000907.1 850642 851010 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 850642..851010 Haemophilus influenzae Rd KW20 949817 NP_438960.1 CDS rpS11 NC_000907.1 851013 851402 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 851013..851402 Haemophilus influenzae Rd KW20 949749 NP_438961.1 CDS rpsD NC_000907.1 851430 852050 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 851430..852050 Haemophilus influenzae Rd KW20 950601 NP_438962.1 CDS rpoA NC_000907.1 852082 853068 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 852082..853068 Haemophilus influenzae Rd KW20 949818 NP_438963.1 CDS rplQ NC_000907.1 853109 853495 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 853109..853495 Haemophilus influenzae Rd KW20 949819 NP_438966.1 CDS HI0806 NC_000907.1 855169 855975 D similar to GB:L77117 SP:Q57883 PID:1591145; hypothetical protein 855169..855975 Haemophilus influenzae Rd KW20 949820 NP_438967.1 CDS HI0807 NC_000907.1 856007 857200 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(856007..857200) Haemophilus influenzae Rd KW20 949821 NP_438968.1 CDS frr NC_000907.1 857310 857867 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(857310..857867) Haemophilus influenzae Rd KW20 949822 NP_438969.1 CDS pckA NC_000907.1 858019 859635 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(858019..859635) Haemophilus influenzae Rd KW20 950742 NP_438970.1 CDS hslO NC_000907.1 859808 860689 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(859808..860689) Haemophilus influenzae Rd KW20 950307 NP_438971.1 CDS argH NC_000907.1 860834 862207 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(860834..862207) Haemophilus influenzae Rd KW20 949824 NP_438972.1 CDS galU NC_000907.1 862342 863229 R similar to GB:M98830 SP:P25520 GB:X59940 PID:146073 PID:42026; glucosephosphate uridylyltransferase complement(862342..863229) Haemophilus influenzae Rd KW20 949826 NP_438973.1 CDS csrA NC_000907.1 863251 863442 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(863251..863442) Haemophilus influenzae Rd KW20 949827 NP_438974.1 CDS alaS NC_000907.1 863520 866144 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(863520..866144) Haemophilus influenzae Rd KW20 950776 NP_438975.1 CDS uspA NC_000907.1 866332 866757 R forms asymmetric homodimer; similar to GB:U00039 SP:P28242 GB:X67639 PID:43280 PID:466632; universal stress protein A complement(866332..866757) Haemophilus influenzae Rd KW20 949495 NP_438976.1 CDS pepP NC_000907.1 866859 868151 R similar to GB:D00398 SP:P15034 PID:216529 PID:216627 PID:882438; aminopeptidase P complement(866859..868151) Haemophilus influenzae Rd KW20 949828 NP_438977.1 CDS HI0817 NC_000907.1 868163 868711 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(868163..868711) Haemophilus influenzae Rd KW20 949830 NP_438978.1 CDS galM NC_000907.1 868882 869904 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(868882..869904) Haemophilus influenzae Rd KW20 949661 NP_438979.2 CDS galK NC_000907.1 869914 871068 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(869914..871068) Haemophilus influenzae Rd KW20 950587 NP_438980.1 CDS galT NC_000907.1 871145 872194 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(871145..872194) Haemophilus influenzae Rd KW20 950798 NP_438981.1 CDS galR NC_000907.1 872402 873400 D similar to SP:P31766 GB:X65934 PID:1573834; LacI family transcriptional repressor 872402..873400 Haemophilus influenzae Rd KW20 949832 NP_438982.2 CDS mglB NC_000907.1 873545 874540 D similar to SP:P02927 GB:K00419 GB:X05646 PID:146853 PID:146857; galactose ABC transporter substrate-binding protein 873545..874540 Haemophilus influenzae Rd KW20 949834 NP_438983.1 CDS mglA NC_000907.1 874606 876126 D with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 874606..876126 Haemophilus influenzae Rd KW20 949835 NP_438984.1 CDS mglC NC_000907.1 876143 877153 D ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 876143..877153 Haemophilus influenzae Rd KW20 949838 NP_438985.1 CDS HI0825 NC_000907.1 877299 878033 D hypothetical protein 877299..878033 Haemophilus influenzae Rd KW20 949928 NP_438986.1 CDS HI0826 NC_000907.1 878039 878596 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 878039..878596 Haemophilus influenzae Rd KW20 949918 NP_438987.1 CDS HI0827 NC_000907.1 878596 879060 D similar to GB:K00431 SP:P04379 PID:455187 PID:902382 PID:902391; hypothetical protein 878596..879060 Haemophilus influenzae Rd KW20 949716 NP_438988.1 CDS HI0828 NC_000907.1 879077 879373 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 879077..879373 Haemophilus influenzae Rd KW20 949842 NP_438989.1 CDS HI0829 NC_000907.1 879389 881170 D similar to GB:U14003 SP:P03810 GB:M69185 PID:147836 PID:537232; soluble lytic murein transglycosylase 879389..881170 Haemophilus influenzae Rd KW20 949843 NP_438990.1 CDS trpR NC_000907.1 881208 881513 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 881208..881513 Haemophilus influenzae Rd KW20 949844 NP_438991.2 CDS mtgA NC_000907.1 881500 882240 D glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 881500..882240 Haemophilus influenzae Rd KW20 949845 NP_438992.1 CDS frdD NC_000907.1 882346 882690 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(882346..882690) Haemophilus influenzae Rd KW20 949846 NP_438993.2 CDS frdC NC_000907.1 882703 883113 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(882703..883113) Haemophilus influenzae Rd KW20 949847 NP_438994.1 CDS frdB NC_000907.1 883124 883894 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(883124..883894) Haemophilus influenzae Rd KW20 949848 NP_438995.1 CDS frdA NC_000907.1 883887 885686 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(883887..885686) Haemophilus influenzae Rd KW20 949849 NP_438996.2 CDS genX NC_000907.1 885898 886869 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 885898..886869 Haemophilus influenzae Rd KW20 949850 NP_438997.1 CDS cpxR NC_000907.1 887135 887818 R similar to GB:L19201 SP:P16244 GB:L14579 GB:X13307 PID:145589; response regulator complement(887135..887818) Haemophilus influenzae Rd KW20 949851 NP_438998.2 CDS HI0838 NC_000907.1 887872 888285 R similar to SP:P23089; small protein A complement(887872..888285) Haemophilus influenzae Rd KW20 949852 NP_438999.2 CDS HI0839 NC_000907.1 888351 889367 R similar to SP:P33920 PID:405914 GB:U00096 PID:1788513; nucleoid-associated protein NdpA complement(888351..889367) Haemophilus influenzae Rd KW20 949853 NP_439000.1 CDS HI0840 NC_000907.1 889493 889711 D similar to SP:P33921 PID:405915 GB:U00096 PID:1788514; hypothetical protein 889493..889711 Haemophilus influenzae Rd KW20 949854 NP_439001.1 CDS HI0841 NC_000907.1 889713 891470 D similar to SP:P33922 PID:453987 GB:U00096 PID:1788515; hypothetical protein 889713..891470 Haemophilus influenzae Rd KW20 949855 NP_439004.1 CDS mobA NC_000907.1 892798 893376 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(892798..893376) Haemophilus influenzae Rd KW20 950590 NP_439005.1 CDS HI0845 NC_000907.1 893463 893729 D similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289; hypothetical protein 893463..893729 Haemophilus influenzae Rd KW20 950597 NP_439006.1 CDS por NC_000907.1 893740 894357 D similar to GB:M94205 SP:P31810 PID:1573860; oxidoreductase 893740..894357 Haemophilus influenzae Rd KW20 949506 NP_439007.1 CDS HI0847 NC_000907.1 894419 894754 D similar to GB:M87049 SP:P27827 PID:148172 GB:U00096 PID:2367277; hypothetical protein 894419..894754 Haemophilus influenzae Rd KW20 950632 NP_439008.1 CDS trmA NC_000907.1 894898 895989 D catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 894898..895989 Haemophilus influenzae Rd KW20 949860 NP_439009.1 CDS HI0849m NC_000907.1 895971 896744 D SAM-dependent methyltransferase 895971..896744 Haemophilus influenzae Rd KW20 949861 NP_439010.1 CDS HI0850 NC_000907.1 896738 897172 D similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096; sigma-E factor regulatory protein 896738..897172 Haemophilus influenzae Rd KW20 949863 NP_439011.1 CDS mobB NC_000907.1 897574 898110 D similar to GB:L19201 SP:P32125 PID:304962 GB:U00096 PID:1790287; molybdopterin-guanine dinucleotide biosynthesis protein B 897574..898110 Haemophilus influenzae Rd KW20 949864 NP_439012.1 CDS HI0852 NC_000907.1 898107 899498 D similar to GB:L10328 SP:P31474 PID:290604 GB:U00096 PID:1790195; hypothetical protein 898107..899498 Haemophilus influenzae Rd KW20 949865 NP_439013.1 CDS dppA NC_000907.1 899639 901288 D similar to GB:M84028 SP:P33950 PID:1573869; heme-binding lipoprotein 899639..901288 Haemophilus influenzae Rd KW20 949866 NP_439014.1 CDS HI0854 NC_000907.1 901464 902225 D similar to GB:AE000511 PID:2313418; heme iron utilization protein 901464..902225 Haemophilus influenzae Rd KW20 949867 NP_439015.1 CDS HI0855 NC_000907.1 902362 902709 R similar to SP:P42626 PID:606050 GB:U00096 PID:1789496; hypothetical protein complement(902362..902709) Haemophilus influenzae Rd KW20 949868 NP_439016.1 CDS polA NC_000907.1 902724 905516 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(902724..905516) Haemophilus influenzae Rd KW20 950729 NP_439017.1 CDS HI0857 NC_000907.1 905665 905967 D similar to SP:P45580 PID:882440 GB:U00096 PID:1789277; hypothetical protein 905665..905967 Haemophilus influenzae Rd KW20 950666 NP_439018.1 CDS HI0858 NC_000907.1 906285 906848 D similar to GB:M12965 SP:P09160 PID:147874 PID:882441 GB:U00096; hypothetical protein 906285..906848 Haemophilus influenzae Rd KW20 949870 NP_439019.1 CDS clpB NC_000907.1 906976 909546 D similar to GB:M29364 SP:P03815 GB:V00350 GB:X57620 PID:1236633; ATP-dependent Clp protease ATPase subunit 906976..909546 Haemophilus influenzae Rd KW20 949871 NP_439020.1 CDS HI0860 NC_000907.1 909583 910323 R Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(909583..910323) Haemophilus influenzae Rd KW20 949872 NP_439021.1 CDS vacB NC_000907.1 910379 912727 R exoribonuclease R; similar to GB:U14003 SP:P21499 PID:537020 GB:U00096 PID:1790622; virulence-associated protein complement(910379..912727) Haemophilus influenzae Rd KW20 949873 NP_439022.1 CDS HI0862 NC_000907.1 912919 913626 R similar to SP:P37619 PID:466607 GB:U00096 PID:1789882; hypothetical protein complement(912919..913626) Haemophilus influenzae Rd KW20 949874 NP_439023.2 CDS pdxH NC_000907.1 913819 914451 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 913819..914451 Haemophilus influenzae Rd KW20 949875 NP_439024.1 CDS HI0864 NC_000907.1 914539 916389 R similar to GB:L19201 SP:P32132 PID:304976 GB:U00096 PID:1790302; GTP-binding protein complement(914539..916389) Haemophilus influenzae Rd KW20 949876 NP_439025.1 CDS glnA NC_000907.1 916620 918038 D similar to SP:P28786 GB:X68129 PID:45900; glutamine synthetase 916620..918038 Haemophilus influenzae Rd KW20 949878 NP_439026.1 CDS HI0866 NC_000907.1 918515 919138 D hypothetical protein 918515..919138 Haemophilus influenzae Rd KW20 950756 NP_439027.1 CDS HI0867 NC_000907.1 919376 920590 D similar to SP:P37781 PID:454902; lipopolysaccharide biosynthesis protein 919376..920590 Haemophilus influenzae Rd KW20 950724 NP_439028.1 CDS HI0868 NC_000907.1 920571 921323 D similar to GB:AL009126; hypothetical protein 920571..921323 Haemophilus influenzae Rd KW20 949464 NP_439032.1 CDS siaA NC_000907.1 923293 924213 D N-acetylneuraminic acid synthase-like protein 923293..924213 Haemophilus influenzae Rd KW20 949881 NP_439033.1 CDS wbaP NC_000907.1 924206 925621 D similar to SP:P26406 GB:X52093 PID:1335815 PID:1335817; undecaprenyl-phosphate galactosephosphotransferase 924206..925621 Haemophilus influenzae Rd KW20 949841 NP_439034.2 CDS rffG NC_000907.1 925683 926696 D similar to GB:M87049 SP:P27830 PID:148191 GB:U00096 PID:1790223; dTDP-glucose 46-dehydratase 925683..926696 Haemophilus influenzae Rd KW20 949510 NP_439035.1 CDS HI0874 NC_000907.1 926749 927948 R hypothetical protein complement(926749..927948) Haemophilus influenzae Rd KW20 949882 NP_439037.1 CDS ndk NC_000907.1 929409 929834 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 929409..929834 Haemophilus influenzae Rd KW20 949884 NP_439038.1 CDS obgE NC_000907.1 929904 931076 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(929904..931076) Haemophilus influenzae Rd KW20 949885 NP_439039.1 CDS HI0878 NC_000907.1 931104 932024 R similar to SP:P28636 PID:216638 PID:606122 GB:U00096 PID:1789575; hypothetical protein complement(931104..932024) Haemophilus influenzae Rd KW20 949421 NP_439040.1 CDS rpmA NC_000907.1 932105 932362 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(932105..932362) Haemophilus influenzae Rd KW20 950621 NP_439041.1 CDS rplU NC_000907.1 932383 932694 R similar to GB:D13267 SP:P02422 PID:216636 PID:606124 GB:U00096; 50S ribosomal protein L21 complement(932383..932694) Haemophilus influenzae Rd KW20 950467 NP_439042.1 CDS ispB NC_000907.1 932907 933896 D similar to SP:P19641 GB:X68873 PID:388220 PID:606125 GB:U00096; octaprenyl-diphosphate synthase 932907..933896 Haemophilus influenzae Rd KW20 949563 NP_439043.1 CDS HI0882 NC_000907.1 933947 934684 D hypothetical protein 933947..934684 Haemophilus influenzae Rd KW20 949886 NP_439044.1 CDS HI0883 NC_000907.1 934743 936113 R similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126; Na+/alanine symporter complement(934743..936113) Haemophilus influenzae Rd KW20 949887 NP_439045.1 CDS arcA NC_000907.1 936511 937221 R similar to SP:P03026 GB:L34010 GB:M10044 PID:1790863; two-component response regulator complement(936511..937221) Haemophilus influenzae Rd KW20 949839 NP_439046.1 CDS dipZ NC_000907.1 937413 939152 D two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 937413..939152 Haemophilus influenzae Rd KW20 950312 NP_439047.1 CDS HI0886 NC_000907.1 939264 939668 D hypothetical protein 939264..939668 Haemophilus influenzae Rd KW20 949888 NP_439048.1 CDS purH NC_000907.1 939856 941454 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 939856..941454 Haemophilus influenzae Rd KW20 949891 NP_439049.1 CDS purD NC_000907.1 941550 942839 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 941550..942839 Haemophilus influenzae Rd KW20 949893 NP_439050.1 CDS glyA NC_000907.1 942963 944228 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 942963..944228 Haemophilus influenzae Rd KW20 949894 NP_439051.1 CDS coaE NC_000907.1 944299 944919 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 944299..944919 Haemophilus influenzae Rd KW20 950766 NP_439052.1 CDS HI0891m NC_000907.1 944912 945118 D zinc-binding protein 944912..945118 Haemophilus influenzae Rd KW20 949368 NP_439053.1 CDS rhlB NC_000907.1 945227 946483 D enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 945227..946483 Haemophilus influenzae Rd KW20 949895 NP_439054.1 CDS HI0893 NC_000907.1 946725 947288 D Bm3T1; similar to GB:S87512 SP:P43506 PID:623036 PID:247052; transcriptional repressor 946725..947288 Haemophilus influenzae Rd KW20 949896 NP_439055.1 CDS HI0894 NC_000907.1 947368 948516 D similar to GB:U14993 SP:P43505 PID:438192 PID:550460; membrane-fusion protein 947368..948516 Haemophilus influenzae Rd KW20 949897 NP_439056.1 CDS acrB NC_000907.1 948516 951614 D similar to GB:M94248 SP:P31224 GB:U00734 PID:290406 PID:532311; acriflavine resistance protein 948516..951614 Haemophilus influenzae Rd KW20 949898 NP_439057.1 CDS ftsN NC_000907.1 952004 952618 D similar to GB:L19201 SP:P29131 GB:L14281 PID:290448 PID:305036; cell division protein 952004..952618 Haemophilus influenzae Rd KW20 949899 NP_439058.1 CDS emrB NC_000907.1 952635 954167 R similar to GB:M86657 SP:P27304 PID:145836 GB:U00096 PID:1789042; multidrug resistance protein B complement(952635..954167) Haemophilus influenzae Rd KW20 949901 NP_439059.1 CDS emrA NC_000907.1 954177 955349 R similar to GB:M86657 SP:P27303 PID:145835 GB:U00096 PID:1789041; multidrug resistance protein A complement(954177..955349) Haemophilus influenzae Rd KW20 949904 NP_439060.1 CDS folA NC_000907.1 955532 956014 R similar to GB:D10483 SP:P00379 GB:J01609 GB:J01609 GB:X05108; dihydrofolate reductase complement(955532..956014) Haemophilus influenzae Rd KW20 949905 NP_439061.1 CDS proB NC_000907.1 956115 957221 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 956115..957221 Haemophilus influenzae Rd KW20 949633 NP_439062.1 CDS HI0901 NC_000907.1 957302 957892 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 957302..957892 Haemophilus influenzae Rd KW20 950618 NP_439063.1 CDS HI0902 NC_000907.1 957892 958686 D similar to GB:L77117 SP:Q57883 PID:1591145; hypothetical protein 957892..958686 Haemophilus influenzae Rd KW20 949698 NP_439064.1 CDS lgt NC_000907.1 958695 959501 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 958695..959501 Haemophilus influenzae Rd KW20 950017 NP_439065.1 CDS thyA NC_000907.1 959511 960362 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 959511..960362 Haemophilus influenzae Rd KW20 949907 NP_439066.1 CDS HI0906 NC_000907.1 960362 960883 D similar to SP:P30134 PID:296183 PID:987637 PID:1033148 GB:U00096; hypothetical protein 960362..960883 Haemophilus influenzae Rd KW20 949908 NP_439067.1 CDS HI0907 NC_000907.1 960911 961225 R hypothetical protein complement(960911..961225) Haemophilus influenzae Rd KW20 949909 NP_439068.1 CDS HI0908 NC_000907.1 961305 961607 D hypothetical protein 961305..961607 Haemophilus influenzae Rd KW20 949910 NP_439069.1 CDS secA NC_000907.1 961732 964437 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 961732..964437 Haemophilus influenzae Rd KW20 949911 NP_439070.1 CDS mutT NC_000907.1 964502 964912 D MutT; similar to GB:D10483 SP:P08337 GB:M20791 GB:X04831 PID:147795; mutator protein 964502..964912 Haemophilus influenzae Rd KW20 949912 NP_439071.1 CDS kefC NC_000907.1 965021 966877 D similar to GB:D10483 SP:P03819 GB:X56742 PID:216472 PID:41875; glutathione-regulated potassium efflux system protein 965021..966877 Haemophilus influenzae Rd KW20 950431 NP_439072.1 CDS HI0912 NC_000907.1 966978 967742 D hypothetical protein 966978..967742 Haemophilus influenzae Rd KW20 950836 NP_439073.2 CDS rpsB NC_000907.1 967920 968642 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 967920..968642 Haemophilus influenzae Rd KW20 949913 NP_439074.1 CDS tsf NC_000907.1 968775 969626 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 968775..969626 Haemophilus influenzae Rd KW20 949917 NP_439075.1 CDS lpxD NC_000907.1 969806 970831 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(969806..970831) Haemophilus influenzae Rd KW20 949919 NP_439076.1 CDS HI0916 NC_000907.1 970844 971437 R similar to PID:1935023; outer membrane protein complement(970844..971437) Haemophilus influenzae Rd KW20 949929 NP_439077.1 CDS HI0917 NC_000907.1 971545 973932 R similar to GB:U13961 PID:1573938 PID:2231192 PID:2231195; protective surface antigen D15 complement(971545..973932) Haemophilus influenzae Rd KW20 949634 NP_439078.1 CDS HI0918 NC_000907.1 973952 975283 R similar to SP:P37764 PID:1208948 GB:U00096 PID:1552753 PID:1786373; hypothetical protein complement(973952..975283) Haemophilus influenzae Rd KW20 949920 NP_439079.1 CDS cdsA NC_000907.1 975293 976159 R similar to GB:M11330 SP:P06466 PID:1208947 PID:145476 GB:U00096; CDP-diglyceride synthetase complement(975293..976159) Haemophilus influenzae Rd KW20 949391 NP_439080.1 CDS HI0920 NC_000907.1 976177 976896 R similar to PID:1208946 GB:U00096 SP:Q47675 PID:1552751 PID:1786371; hypothetical protein complement(976177..976896) Haemophilus influenzae Rd KW20 950624 NP_439081.1 CDS leuS NC_000907.1 977145 979730 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 977145..979730 Haemophilus influenzae Rd KW20 949390 NP_439082.2 CDS HI0922 NC_000907.1 979825 980328 D similar to GB:M18277 SP:P10101 PID:147663 GB:U00096 PID:1651268; rare lipoprotein B 979825..980328 Haemophilus influenzae Rd KW20 950738 NP_439083.1 CDS holA NC_000907.1 980328 981362 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 980328..981362 Haemophilus influenzae Rd KW20 949921 NP_439084.1 CDS glyS NC_000907.1 981597 983663 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(981597..983663) Haemophilus influenzae Rd KW20 949922 NP_439085.1 CDS HI0925 NC_000907.1 984000 984365 R similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546; hypothetical protein complement(984000..984365) Haemophilus influenzae Rd KW20 950812 NP_439086.1 CDS HI0926 NC_000907.1 984395 984655 R hypothetical protein complement(984395..984655) Haemophilus influenzae Rd KW20 949651 NP_439087.1 CDS glyQ NC_000907.1 984714 985622 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(984714..985622) Haemophilus influenzae Rd KW20 950664 NP_439088.1 CDS hktE NC_000907.1 985888 987414 D similar to GB:U02682 PID:1573949; catalase 985888..987414 Haemophilus influenzae Rd KW20 949926 NP_439089.1 CDS HI0929 NC_000907.1 987646 988827 R similar to GB:M77129 SP:P24196 PID:146678 PID:882568 GB:U00096; hypothetical protein complement(987646..988827) Haemophilus influenzae Rd KW20 949927 NP_439090.1 CDS HI0930 NC_000907.1 988828 989448 R hypothetical protein complement(988828..989448) Haemophilus influenzae Rd KW20 949932 NP_439091.2 CDS HI0931 NC_000907.1 989421 989840 R hypothetical protein complement(989421..989840) Haemophilus influenzae Rd KW20 949933 NP_439092.1 CDS eno NC_000907.1 989924 991234 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(989924..991234) Haemophilus influenzae Rd KW20 949935 NP_439093.1 CDS HI0933 NC_000907.1 991355 992560 R similar to SP:P37631 PID:912464 GB:U00096 PID:2367234; hypothetical protein complement(991355..992560) Haemophilus influenzae Rd KW20 949936 NP_439094.1 CDS nrfF NC_000907.1 992557 993711 R similar to SP:P32711 GB:X72298 PID:396410 PID:404307 GB:U00096; cytochrome C-type biogenesis protein complement(992557..993711) Haemophilus influenzae Rd KW20 949938 NP_439095.1 CDS dsbE NC_000907.1 993708 994238 R similar to SP:P33926 PID:405920 GB:U00096 PID:1788523; thiol-disulfide interchange protein complement(993708..994238) Haemophilus influenzae Rd KW20 949930 NP_439096.1 CDS HI0936 NC_000907.1 994238 996145 R similar to SP:P32710 GB:X72298 PID:581146 GB:U00096 PID:1790511; cytochrome C-type biogenesis complement(994238..996145) Haemophilus influenzae Rd KW20 950731 NP_439097.1 CDS suhB NC_000907.1 996254 997057 R similar to GB:M34828 SP:P22783 PID:147899 GB:U00096 PID:1788882; extragenic suppressor complement(996254..997057) Haemophilus influenzae Rd KW20 949915 NP_439098.1 CDS HI0938 NC_000907.1 997258 997770 D hypothetical protein 997258..997770 Haemophilus influenzae Rd KW20 949906 NP_439099.1 CDS HI0939 NC_000907.1 997770 998486 D hypothetical protein 997770..998486 Haemophilus influenzae Rd KW20 949939 NP_439100.1 CDS HI0940 NC_000907.1 998486 999169 D hypothetical protein 998486..999169 Haemophilus influenzae Rd KW20 949941 NP_439101.1 CDS HI0941 NC_000907.1 999144 999449 D hypothetical protein 999144..999449 Haemophilus influenzae Rd KW20 950292 NP_439102.1 CDS recC NC_000907.1 999495 1002860 D similar to SP:P07648 PID:42689 PID:882714 GB:U00096 PID:1789186; exodeoxyribonuclease V subunit gamma 999495..1002860 Haemophilus influenzae Rd KW20 950610 NP_439103.1 CDS nrdR NC_000907.1 1002915 1003364 D similar to SP:P25538 GB:X64395 PID:42148 GB:U00096 PID:1773097; transcriptional regulator NrdR 1002915..1003364 Haemophilus influenzae Rd KW20 949508 NP_439104.1 CDS ribD NC_000907.1 1003367 1004485 D similar to SP:P25539 GB:X64395 PID:581147 GB:U00096 PID:1773098; riboflavin biosynthesis protein 1003367..1004485 Haemophilus influenzae Rd KW20 949944 NP_439105.1 CDS degS NC_000907.1 1004486 1005508 D similar to SP:P31137 GB:U15661 GB:U00096 PID:1789630; protease 1004486..1005508 Haemophilus influenzae Rd KW20 949947 NP_439106.1 CDS fpg NC_000907.1 1005582 1006397 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1005582..1006397) Haemophilus influenzae Rd KW20 949949 NP_439107.1 CDS HI0946.1 NC_000907.1 1006630 1008165 R similar to PID:893355; L-24-diaminobutyrate decarboxylase complement(1006630..1008165) Haemophilus influenzae Rd KW20 950216 NP_439108.1 CDS vapC NC_000907.1 1008185 1008583 R similar to GB:L22308 GB:L31763 GB:M74565 PID:145068 PID:438534; virulence-associated protein C complement(1008185..1008583) Haemophilus influenzae Rd KW20 950223 NP_439109.1 CDS HI0948 NC_000907.1 1008583 1008816 R similar to SP:P18355; hypothetical protein complement(1008583..1008816) Haemophilus influenzae Rd KW20 949840 NP_439110.1 CDS HI0949 NC_000907.1 1008963 1010327 R catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase complement(1008963..1010327) Haemophilus influenzae Rd KW20 949951 NP_439111.1 CDS rpmG NC_000907.1 1010675 1010845 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1010675..1010845) Haemophilus influenzae Rd KW20 949952 NP_439112.1 CDS rpmB NC_000907.1 1010857 1011093 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1010857..1011093) Haemophilus influenzae Rd KW20 949955 NP_439113.2 CDS radC NC_000907.1 1011307 1011972 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1011307..1011972) Haemophilus influenzae Rd KW20 949958 NP_439114.1 CDS dfp NC_000907.1 1012136 1013338 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1012136..1013338 Haemophilus influenzae Rd KW20 949948 NP_439115.1 CDS dut NC_000907.1 1013386 1013841 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1013386..1013841 Haemophilus influenzae Rd KW20 949940 NP_439116.1 CDS slmA NC_000907.1 1013845 1014501 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 1013845..1014501 Haemophilus influenzae Rd KW20 949937 NP_439118.1 CDS crp NC_000907.1 1014760 1015434 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 1014760..1015434 Haemophilus influenzae Rd KW20 949963 NP_439119.1 CDS rumB NC_000907.1 1015799 1016977 R RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase complement(1015799..1016977) Haemophilus influenzae Rd KW20 949964 NP_439120.1 CDS exoII NC_000907.1 1016970 1018025 R hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(1016970..1018025) Haemophilus influenzae Rd KW20 949658 NP_439121.1 CDS HI0960 NC_000907.1 1018029 1018379 R hypothetical protein complement(1018029..1018379) Haemophilus influenzae Rd KW20 950757 NP_439122.2 CDS HI0961 NC_000907.1 1018379 1018729 R similar to SP:P44956; HIT-like protein complement(1018379..1018729) Haemophilus influenzae Rd KW20 950594 NP_439124.1 CDS ribF NC_000907.1 1021700 1022638 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(1021700..1022638) Haemophilus influenzae Rd KW20 949965 NP_439125.1 CDS mviN NC_000907.1 1022673 1024205 R similar to GB:D25292 SP:P37169 GB:Z26133 PID:438252 PID:505363; virulence factor complement(1022673..1024205) Haemophilus influenzae Rd KW20 950595 NP_439126.2 CDS rpsT NC_000907.1 1024514 1024777 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1024514..1024777 Haemophilus influenzae Rd KW20 950750 NP_439127.1 CDS HI0966 NC_000907.1 1024850 1025416 R hypothetical protein complement(1024850..1025416) Haemophilus influenzae Rd KW20 950444 NP_439128.1 CDS HI0967 NC_000907.1 1025442 1025546 D hypothetical protein 1025442..1025546 Haemophilus influenzae Rd KW20 949914 NP_439129.1 CDS menB NC_000907.1 1025562 1026419 D catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1025562..1026419 Haemophilus influenzae Rd KW20 949967 NP_439130.2 CDS menC NC_000907.1 1026452 1027477 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 1026452..1027477 Haemophilus influenzae Rd KW20 949968 NP_439131.1 CDS aroQ NC_000907.1 1027535 1027984 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1027535..1027984 Haemophilus influenzae Rd KW20 949969 NP_439132.1 CDS accB NC_000907.1 1028137 1028604 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1028137..1028604 Haemophilus influenzae Rd KW20 949974 NP_439133.1 CDS accC NC_000907.1 1028779 1030125 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1028779..1030125 Haemophilus influenzae Rd KW20 949398 NP_439134.1 CDS HI0973 NC_000907.1 1030275 1031144 D hypothetical protein 1030275..1031144 Haemophilus influenzae Rd KW20 949511 NP_439136.1 CDS HI0974.1 NC_000907.1 1032765 1033022 D similar to SP:P45566 PID:606197 GB:U00096 PID:1789655; hypothetical protein 1032765..1033022 Haemophilus influenzae Rd KW20 949407 NP_439137.1 CDS panF NC_000907.1 1033019 1034473 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 1033019..1034473 Haemophilus influenzae Rd KW20 950256 NP_439140.1 CDS fic NC_000907.1 1035466 1036041 D similar to GB:M28363 SP:P20605 PID:145955 PID:147054 PID:606295; cell filamentation protein 1035466..1036041 Haemophilus influenzae Rd KW20 949973 NP_439141.1 CDS prmA NC_000907.1 1036082 1036972 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1036082..1036972 Haemophilus influenzae Rd KW20 949962 NP_439142.1 CDS HI0979 NC_000907.1 1037121 1038113 D similar to SP:P45672 PID:599600; hypothetical protein 1037121..1038113 Haemophilus influenzae Rd KW20 949982 NP_439143.1 CDS fis NC_000907.1 1038094 1038393 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 1038094..1038393 Haemophilus influenzae Rd KW20 949985 NP_439144.1 CDS smpB NC_000907.1 1038488 1038973 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1038488..1038973) Haemophilus influenzae Rd KW20 950039 NP_439145.1 CDS pfkA NC_000907.1 1039212 1040177 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1039212..1040177) Haemophilus influenzae Rd KW20 949556 NP_439146.1 CDS HI0983 NC_000907.1 1040273 1040854 R hypothetical protein complement(1040273..1040854) Haemophilus influenzae Rd KW20 949986 NP_439147.2 CDS HI0984 NC_000907.1 1040847 1041623 R similar to GB:D10483 SP:P11288 PID:216438 PID:537248 PID:1128976; hypothetical protein complement(1040847..1041623) Haemophilus influenzae Rd KW20 949993 NP_439148.1 CDS dprA NC_000907.1 1041677 1042798 R similar to GB:L42023 SP:P43862 PID:1006171 PID:1221098 PID:609332; DNA processing chain A complement(1041677..1042798) Haemophilus influenzae Rd KW20 949984 NP_439149.2 CDS leuA NC_000907.1 1043355 1044902 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1043355..1044902 Haemophilus influenzae Rd KW20 949987 NP_439150.1 CDS leuB NC_000907.1 1044988 1046064 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1044988..1046064 Haemophilus influenzae Rd KW20 949989 NP_439151.1 CDS leuC NC_000907.1 1046240 1047649 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1046240..1047649 Haemophilus influenzae Rd KW20 950815 NP_439152.1 CDS leuD NC_000907.1 1047673 1048275 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1047673..1048275 Haemophilus influenzae Rd KW20 949559 NP_439153.1 CDS iga1 NC_000907.1 1048389 1053473 R similar to GB:M87489; immunoglobin A1 protease complement(1048389..1053473) Haemophilus influenzae Rd KW20 950762 NP_439154.1 CDS recF NC_000907.1 1053715 1054794 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(1053715..1054794) Haemophilus influenzae Rd KW20 949990 NP_439155.1 CDS dnaN NC_000907.1 1054796 1055896 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(1054796..1055896) Haemophilus influenzae Rd KW20 949992 NP_439156.1 CDS dnaA NC_000907.1 1055909 1057273 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(1055909..1057273) Haemophilus influenzae Rd KW20 950755 NP_439157.1 CDS tbp1 NC_000907.1 1057465 1060203 R similar to GB:Z15129 SP:Q06987 GB:S64486 GB:X75168 PID:297044; transferrin-binding protein 1 complement(1057465..1060203) Haemophilus influenzae Rd KW20 950660 NP_439158.1 CDS tbp2 NC_000907.1 1060231 1062108 R similar to PID:1177569; transferrin-binding protein 2 complement(1060231..1062108) Haemophilus influenzae Rd KW20 950797 NP_439160.1 CDS rpmH NC_000907.1 1063832 1063966 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1063832..1063966 Haemophilus influenzae Rd KW20 949994 NP_439161.1 CDS rnpA NC_000907.1 1063986 1064345 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1063986..1064345 Haemophilus influenzae Rd KW20 950612 NP_439162.1 CDS HI1000 NC_000907.1 1064309 1064569 D similar to PID:1005414; hypothetical protein 1064309..1064569 Haemophilus influenzae Rd KW20 949902 NP_439163.1 CDS yidC NC_000907.1 1064569 1066194 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1064569..1066194 Haemophilus influenzae Rd KW20 949995 NP_439164.1 CDS trmE NC_000907.1 1066325 1067710 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1066325..1067710 Haemophilus influenzae Rd KW20 949988 NP_439165.2 CDS HI1004 NC_000907.1 1067898 1069767 D contains frameshifts; similar to GB:U00096 SP:P77241 PID:1580712 PID:1773125 PID:1786645; peptidyl-prolyl cis-trans isomerase join(1067898..1068025,1068027..1069767) Haemophilus influenzae Rd KW20 950512 NP_439166.1 CDS HI1005 NC_000907.1 1069855 1071414 D similar to HI1064; similar to GB:U00096 SP:P75785 PID:1787035; hypothetical protein 1069855..1071414 Haemophilus influenzae Rd KW20 949997 NP_439167.1 CDS lspA NC_000907.1 1071484 1071999 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1071484..1071999 Haemophilus influenzae Rd KW20 949998 NP_439168.1 CDS ispH NC_000907.1 1071996 1072940 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1071996..1072940 Haemophilus influenzae Rd KW20 950001 NP_439169.1 CDS HI1008 NC_000907.1 1073118 1073456 D similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646; hypothetical protein 1073118..1073456 Haemophilus influenzae Rd KW20 950002 NP_439170.1 CDS glpR NC_000907.1 1073504 1074274 R similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096; glycerol-3-phosphate regulon repressor complement(1073504..1074274) Haemophilus influenzae Rd KW20 950712 NP_439171.1 CDS HI1010 NC_000907.1 1074433 1075338 D similar to PID:882629 GB:U00096 PID:1789092; 3-hydroxyisobutyrate dehydrogenase 1074433..1075338 Haemophilus influenzae Rd KW20 950607 NP_439172.1 CDS HI1011 NC_000907.1 1075341 1076582 D similar to PID:882630 GB:U00096 PID:1789093; hypothetical protein 1075341..1076582 Haemophilus influenzae Rd KW20 950004 NP_439173.1 CDS HI1012 NC_000907.1 1076579 1077211 D similar to PID:882631 GB:U00096 SP:Q46890 PID:1789094; aldolase 1076579..1077211 Haemophilus influenzae Rd KW20 950005 NP_439174.1 CDS HI1013 NC_000907.1 1077214 1077990 D similar to PID:882632 GB:U00096 SP:Q46891 PID:1789095; hypothetical protein 1077214..1077990 Haemophilus influenzae Rd KW20 950733 NP_439175.1 CDS HI1014 NC_000907.1 1078046 1078993 D similar to PID:695275; hypothetical protein 1078046..1078993 Haemophilus influenzae Rd KW20 950006 NP_439176.1 CDS gntP NC_000907.1 1079002 1080468 D similar to SP:P39835 PID:606350 GB:U00096 PID:1789820; gluconate permease 1079002..1080468 Haemophilus influenzae Rd KW20 950013 NP_439177.1 CDS HI1016 NC_000907.1 1080488 1080916 D hypothetical protein 1080488..1080916 Haemophilus influenzae Rd KW20 949991 NP_439179.1 CDS tbpA NC_000907.1 1082773 1083771 D similar to GB:D10483 SP:P31550 GB:U09984 PID:216488 PID:497658; thiamin ABC transporter substrate-binding protein 1082773..1083771 Haemophilus influenzae Rd KW20 949440 NP_439180.1 CDS thiP NC_000907.1 1083776 1085392 D permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1083776..1085392 Haemophilus influenzae Rd KW20 950718 NP_439181.1 CDS HI1021 NC_000907.1 1085376 1086023 D similar to GB:D10483 SP:P31548 PID:216486 GB:U00096 PID:1786253; thiamin ABC transporter ATP-binding protein 1085376..1086023 Haemophilus influenzae Rd KW20 950003 NP_439182.1 CDS bioB NC_000907.1 1086136 1087137 D similar to GB:J04423 SP:P12996 PID:145425 PID:490219 GB:U00096; biotin synthetase 1086136..1087137 Haemophilus influenzae Rd KW20 950009 NP_439183.1 CDS tktA NC_000907.1 1087262 1089259 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1087262..1089259) Haemophilus influenzae Rd KW20 949889 NP_439184.1 CDS ulaD NC_000907.1 1089388 1090065 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1089388..1090065) Haemophilus influenzae Rd KW20 950714 NP_439185.1 CDS sgbE NC_000907.1 1090115 1090810 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(1090115..1090810) Haemophilus influenzae Rd KW20 950011 NP_439186.1 CDS HI1026 NC_000907.1 1090804 1091664 R L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase complement(1090804..1091664) Haemophilus influenzae Rd KW20 950012 NP_439187.1 CDS lyx NC_000907.1 1091678 1093135 R similar to SP:P37677 PID:466718 GB:U00096 PID:1790005; L-xylulose kinase complement(1091678..1093135) Haemophilus influenzae Rd KW20 949892 NP_439188.1 CDS HI1028 NC_000907.1 1093194 1094180 R similar to SP:P37676 PID:466717 GB:U00096 PID:1790004; hypothetical protein complement(1093194..1094180) Haemophilus influenzae Rd KW20 949528 NP_439189.1 CDS HI1029 NC_000907.1 1094211 1095488 R similar to SP:P37675 PID:466716 GB:U00096 PID:1790003; hypothetical protein complement(1094211..1095488) Haemophilus influenzae Rd KW20 949652 NP_439190.1 CDS HI1030 NC_000907.1 1095485 1095970 R similar to SP:P37674 PID:466715 GB:U00096 PID:1790002; hypothetical protein complement(1095485..1095970) Haemophilus influenzae Rd KW20 950014 NP_439191.1 CDS HI1031 NC_000907.1 1096042 1097040 R NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase complement(1096042..1097040) Haemophilus influenzae Rd KW20 950015 NP_439192.1 CDS HI1032 NC_000907.1 1097216 1098022 D similar to SP:P37671 PID:466712 GB:U00096 PID:1789999; transcriptional regulator 1097216..1098022 Haemophilus influenzae Rd KW20 950700 NP_439193.1 CDS serB NC_000907.1 1098172 1099116 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 1098172..1099116 Haemophilus influenzae Rd KW20 949401 NP_439194.1 CDS HI1034 NC_000907.1 1099134 1099625 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 1099134..1099625 Haemophilus influenzae Rd KW20 950728 NP_439195.1 CDS corA NC_000907.1 1099920 1100867 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 1099920..1100867 Haemophilus influenzae Rd KW20 950726 NP_439196.2 CDS HI1036 NC_000907.1 1100867 1101412 D similar to PID:801880 SP:P52059 PID:801882; hypothetical protein 1100867..1101412 Haemophilus influenzae Rd KW20 950018 NP_439197.1 CDS HI1037 NC_000907.1 1101593 1102477 R similar to PID:984579 GB:U00096 SP:Q47147 PID:1552793 PID:1786417; hypothetical protein complement(1101593..1102477) Haemophilus influenzae Rd KW20 950020 NP_439198.1 CDS HI1038 NC_000907.1 1102856 1104058 D similar to GB:L77117 PID:1592175; hypothetical protein 1102856..1104058 Haemophilus influenzae Rd KW20 950021 NP_439199.1 CDS ureF NC_000907.1 1104411 1105415 D similar to SP:P25261 SP:P24599 PID:43474; urease accessory protein 1104411..1105415 Haemophilus influenzae Rd KW20 950604 NP_439200.1 CDS HI1041 NC_000907.1 1105412 1106326 D similar to SP:P24600 SP:P25267 PID:43482; modification methylase 1105412..1106326 Haemophilus influenzae Rd KW20 950661 NP_439202.1 CDS napF NC_000907.1 1108431 1108931 R similar to SP:P33939 PID:453990 GB:U00096 PID:1736849 PID:1788536; ferredoxin-type protein complement(1108431..1108931) Haemophilus influenzae Rd KW20 950023 NP_439203.1 CDS HI1044 NC_000907.1 1108931 1109542 R binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD complement(1108931..1109542) Haemophilus influenzae Rd KW20 950592 NP_439204.1 CDS dmsC NC_000907.1 1109654 1110493 R similar to GB:J03412 SP:P18777 PID:145757 GB:U00096 PID:1651423; anaerobic dimethyl sulfoxide reductase subunit C complement(1109654..1110493) Haemophilus influenzae Rd KW20 950571 NP_439205.1 CDS dmsB NC_000907.1 1110495 1111112 R similar to GB:J03412 SP:P18776 PID:145756 GB:U00096 PID:1742612; anaerobic dimethyl sulfoxide reductase subunit B complement(1110495..1111112) Haemophilus influenzae Rd KW20 950772 NP_439206.1 CDS dmsA NC_000907.1 1111123 1113543 R similar to GB:J03412 SP:P18775 PID:145755 GB:U00096 PID:1651421; anaerobic dimethyl sulfoxide reductase subunit A complement(1111123..1113543) Haemophilus influenzae Rd KW20 950024 NP_439207.1 CDS HI1048 NC_000907.1 1113797 1114906 D hypothetical protein 1113797..1114906 Haemophilus influenzae Rd KW20 949536 NP_439208.1 CDS merT NC_000907.1 1114948 1115241 D similar to SP:P04140 GB:Z00027 PID:154899 PID:43716; mercuric ion transport protein 1114948..1115241 Haemophilus influenzae Rd KW20 949946 NP_439209.1 CDS merP NC_000907.1 1115250 1115528 D similar to PID:1143574 SP:Q54463; mercuric ion scavenger protein 1115250..1115528 Haemophilus influenzae Rd KW20 950027 NP_439210.1 CDS HI1051 NC_000907.1 1115653 1117497 R similar to GB:AL009126; ABC transporter ATP-binding protein complement(1115653..1117497) Haemophilus influenzae Rd KW20 950028 NP_439211.1 CDS HI1052 NC_000907.1 1117575 1118471 R similar to SP:P35319 PID:581707; AraC family transcriptional regulator complement(1117575..1118471) Haemophilus influenzae Rd KW20 950029 NP_439212.1 CDS HI1053 NC_000907.1 1118583 1118924 D similar to GB:M66060 SP:P27749 PID:141897; hypothetical protein 1118583..1118924 Haemophilus influenzae Rd KW20 950030 NP_439215.1 CDS HI1056 NC_000907.1 1121801 1123690 R type III restriction-modification system methyltransferase-like protein complement(1121801..1123690) Haemophilus influenzae Rd KW20 950036 NP_439216.1 CDS HI1058 NC_000907.1 1123464 1124048 R hypothetical protein complement(1123464..1124048) Haemophilus influenzae Rd KW20 949400 NP_439217.1 CDS rnhB NC_000907.1 1124264 1124857 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1124264..1124857) Haemophilus influenzae Rd KW20 950033 NP_439218.1 CDS lpxB NC_000907.1 1124850 1126022 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(1124850..1126022) Haemophilus influenzae Rd KW20 950031 NP_439219.1 CDS lpxA NC_000907.1 1126089 1126877 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1126089..1126877) Haemophilus influenzae Rd KW20 950038 NP_439220.1 CDS fabZ NC_000907.1 1126891 1127337 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1126891..1127337) Haemophilus influenzae Rd KW20 950037 NP_439223.1 CDS pyrH NC_000907.1 1129110 1129823 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1129110..1129823 Haemophilus influenzae Rd KW20 950042 NP_439224.1 CDS nrfD NC_000907.1 1130062 1131027 R similar to SP:P32709 GB:X72298 PID:396408 PID:404305 GB:U00096; nitrite reductase transmembrane protein complement(1130062..1131027) Haemophilus influenzae Rd KW20 950044 NP_439225.1 CDS nrfC NC_000907.1 1131024 1131701 R similar to SP:P32708 GB:X72298 PID:396407 PID:404304 GB:U00096; nitrite reductase Fe-S protein complement(1131024..1131701) Haemophilus influenzae Rd KW20 950045 NP_439226.2 CDS nrfB NC_000907.1 1131698 1132345 R part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit complement(1131698..1132345) Haemophilus influenzae Rd KW20 950046 NP_439227.3 CDS nrfA NC_000907.1 1132422 1134038 R catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 complement(1132422..1134038) Haemophilus influenzae Rd KW20 950047 NP_439228.2 CDS hrpa NC_000907.1 1134200 1138042 R involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA complement(1134200..1138042) Haemophilus influenzae Rd KW20 950050 NP_439229.1 CDS HI1073 NC_000907.1 1138111 1138485 R similar to SP:P32065 GB:U01030 GB:X73413 PID:312767 PID:523332; hypothetical protein complement(1138111..1138485) Haemophilus influenzae Rd KW20 950051 NP_439230.1 CDS HI1074 NC_000907.1 1138486 1138938 R similar to GB:U00096 PID:1788090; hypothetical protein complement(1138486..1138938) Haemophilus influenzae Rd KW20 950048 NP_439231.1 CDS cydB NC_000907.1 1139203 1140339 R similar to GB:J03939 SP:P11027 PID:145640 GB:U00096 PID:1651328; cytochrome oxidase subunit II complement(1139203..1140339) Haemophilus influenzae Rd KW20 949877 NP_439232.1 CDS cydA NC_000907.1 1140354 1141919 R similar to GB:J03939 SP:P11026 PID:497637 GB:U00096 PID:1651327; cytochrome D ubiquinol oxidase subunit I complement(1140354..1141919) Haemophilus influenzae Rd KW20 950049 NP_439233.1 CDS pyrG NC_000907.1 1142571 1144208 D CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1142571..1144208 Haemophilus influenzae Rd KW20 950052 NP_439235.2 CDS HI1078 NC_000907.1 1145211 1145978 R similar to SP:P39456; amino-acid ABC transporter ATP-binding protein complement(1145211..1145978) Haemophilus influenzae Rd KW20 950054 NP_439236.1 CDS HI1079m NC_000907.1 1145988 1146704 R amino acid ABC transporter permease complement(1145988..1146704) Haemophilus influenzae Rd KW20 949554 NP_439237.1 CDS HI1080 NC_000907.1 1146688 1147461 R similar to SP:P42199; amino acid ABC transporter substrate-binding protein complement(1146688..1147461) Haemophilus influenzae Rd KW20 950096 NP_439238.1 CDS murZ NC_000907.1 1147762 1149036 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1147762..1149036) Haemophilus influenzae Rd KW20 950056 NP_439239.1 CDS HI1082 NC_000907.1 1149047 1149304 R similar to SP:P43781 PID:606128 GB:U00096 PID:1789581; hypothetical protein complement(1149047..1149304) Haemophilus influenzae Rd KW20 949428 NP_439240.1 CDS HI1083 NC_000907.1 1149325 1149642 R similar to GB:M34995 SP:P17903 GB:L35574 PID:143458 PID:1881281; NTP binding protein complement(1149325..1149642) Haemophilus influenzae Rd KW20 950057 NP_439241.1 CDS HI1084 NC_000907.1 1149653 1150297 R similar to SP:P45390 PID:606130 GB:U00096 PID:1789583; ABC transporter complement(1149653..1150297) Haemophilus influenzae Rd KW20 950058 NP_439242.1 CDS HI1085 NC_000907.1 1150327 1150830 R similar to SP:P45391 PID:606131 GB:U00096 PID:1789584; ABC transporter substrate-binding protein complement(1150327..1150830) Haemophilus influenzae Rd KW20 950060 NP_439243.1 CDS HI1086 NC_000907.1 1150841 1151626 R similar to SP:P45392 PID:606132 GB:U00096 PID:1789585; ABC transporter permease complement(1150841..1151626) Haemophilus influenzae Rd KW20 950061 NP_439244.1 CDS HI1087 NC_000907.1 1151623 1152417 R similar to SP:P45393 PID:606133 GB:U00096 PID:1789586; ABC transporter ATPase complement(1151623..1152417) Haemophilus influenzae Rd KW20 950090 NP_439245.1 CDS sodA NC_000907.1 1152847 1153494 R similar to GB:X73832 PID:1574643; superoxide dismutase complement(1152847..1153494) Haemophilus influenzae Rd KW20 950093 NP_439246.1 CDS ccmA NC_000907.1 1153743 1154381 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1153743..1154381 Haemophilus influenzae Rd KW20 949617 NP_439247.1 CDS ccmB NC_000907.1 1154386 1155051 D similar to SP:P33930 PID:405925 GB:U00096 PID:1788528; heme exporter protein B 1154386..1155051 Haemophilus influenzae Rd KW20 950092 NP_439248.1 CDS ccmC NC_000907.1 1155109 1155849 D similar to SP:P33929 PID:405924 GB:U00096 PID:1788527; heme exporter protein C 1155109..1155849 Haemophilus influenzae Rd KW20 950063 NP_439249.1 CDS ccmD NC_000907.1 1155891 1156094 D similar to SP:P36770 PID:453988 GB:U00096 PID:1788526; heme exporter protein D 1155891..1156094 Haemophilus influenzae Rd KW20 950064 NP_439250.1 CDS ccmE NC_000907.1 1156091 1156612 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 1156091..1156612 Haemophilus influenzae Rd KW20 950065 NP_439251.1 CDS ccmF NC_000907.1 1156609 1158555 D similar to SP:P33927 PID:405921 GB:U00096 PID:1788524; cytochrome C-type biogenesis protein 1156609..1158555 Haemophilus influenzae Rd KW20 950066 NP_439252.1 CDS dsbE NC_000907.1 1158694 1159239 D similar to SP:P33926 PID:405920 GB:U00096 PID:1788523; thiol-disulfide interchange protein 1158694..1159239 Haemophilus influenzae Rd KW20 950067 NP_439253.1 CDS ccmH NC_000907.1 1159239 1159700 D cytochrome C-type biogenesis protein 1159239..1159700 Haemophilus influenzae Rd KW20 950062 NP_439254.1 CDS HI1097m NC_000907.1 1159701 1160618 D hypothetical protein 1159701..1160618 Haemophilus influenzae Rd KW20 950550 NP_439256.1 CDS HI1099 NC_000907.1 1161239 1161547 D hypothetical protein 1161239..1161547 Haemophilus influenzae Rd KW20 950069 NP_439257.2 CDS ligA NC_000907.1 1161552 1163564 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1161552..1163564) Haemophilus influenzae Rd KW20 950070 NP_439258.1 CDS HI1101 NC_000907.1 1163676 1164662 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(1163676..1164662) Haemophilus influenzae Rd KW20 950071 NP_439259.1 CDS cysZ NC_000907.1 1164815 1165633 D role in sulfur assimilation; sulfate transport protein CysZ 1164815..1165633 Haemophilus influenzae Rd KW20 950075 NP_439260.1 CDS cysK NC_000907.1 1165732 1166682 D similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201; cysteine synthetase 1165732..1166682 Haemophilus influenzae Rd KW20 950077 NP_439261.1 CDS HI1104 NC_000907.1 1167406 1168629 D similar to PID:1842056; transporter protein 1167406..1168629 Haemophilus influenzae Rd KW20 950078 NP_439262.1 CDS rfaF NC_000907.1 1168738 1169778 R similar to SP:P37692 PID:466758 GB:U00096 PID:1790050; ADP-heptose-LPS heptosyltransferase II complement(1168738..1169778) Haemophilus influenzae Rd KW20 950079 NP_439263.1 CDS xylR NC_000907.1 1169854 1171017 R similar to SP:P37390 PID:466707 GB:U00096 PID:1789993; xylose operon regulatory protein complement(1169854..1171017) Haemophilus influenzae Rd KW20 949767 NP_439264.1 CDS nhaC NC_000907.1 1171129 1172535 R similar to GB:U61539 SP:P27611 PID:143245 PID:2209268; Na+/H+ antiporter complement(1171129..1172535) Haemophilus influenzae Rd KW20 950734 NP_439266.1 CDS xylH NC_000907.1 1173984 1175111 R similar to SP:P37389 PID:466706 GB:U00096 PID:1789992; D-xylose ABC transporter permease complement(1173984..1175111) Haemophilus influenzae Rd KW20 950080 NP_439267.1 CDS xylG NC_000907.1 1175115 1176626 R with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding protein complement(1175115..1176626) Haemophilus influenzae Rd KW20 950081 NP_439268.1 CDS xylF NC_000907.1 1176677 1177675 R periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF complement(1176677..1177675) Haemophilus influenzae Rd KW20 950082 NP_439269.1 CDS xylA NC_000907.1 1177909 1179228 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1177909..1179228 Haemophilus influenzae Rd KW20 950068 NP_439270.1 CDS HI1113 NC_000907.1 1179231 1180766 D similar to PID:2293419; xylulose kinase 1179231..1180766 Haemophilus influenzae Rd KW20 950087 NP_439271.1 CDS rfaD NC_000907.1 1180817 1181743 R catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-mannoheptose-6-epimerase complement(1180817..1181743) Haemophilus influenzae Rd KW20 950083 NP_439272.1 CDS HI1115 NC_000907.1 1181796 1182299 R similar to PID:1213065 SP:P52229; thioredoxin complement(1181796..1182299) Haemophilus influenzae Rd KW20 950780 NP_439273.1 CDS deoC NC_000907.1 1182410 1183081 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1182410..1183081 Haemophilus influenzae Rd KW20 950311 NP_439274.1 CDS comM NC_000907.1 1183115 1184644 R similar to GB:M37337 SP:P22787 PID:147774 PID:147775 PID:148173; competence protein complement(1183115..1184644) Haemophilus influenzae Rd KW20 950645 NP_439275.1 CDS engB NC_000907.1 1184759 1185376 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1184759..1185376) Haemophilus influenzae Rd KW20 950084 NP_439276.1 CDS lapB NC_000907.1 1185469 1186347 D similar to SP:P32181 GB:M59210 PID:387858; membrane protein 1185469..1186347 Haemophilus influenzae Rd KW20 950085 NP_439277.1 CDS oppF NC_000907.1 1186387 1187385 R similar to GB:U00096 SP:P77737 PID:1742036 PID:1787500 PID:1805528; oligopeptide ABC transporter ATP-binding protein complement(1186387..1187385) Haemophilus influenzae Rd KW20 950088 NP_439278.1 CDS oppD NC_000907.1 1187382 1188353 R similar to SP:P04285 GB:X05491 GB:X52093 PID:47805; oligopeptide transporter ATP-binding protein complement(1187382..1188353) Haemophilus influenzae Rd KW20 950089 NP_439279.1 CDS oppC NC_000907.1 1188363 1189298 R similar to SP:P08006 GB:X05491 GB:X52093 PID:47804; oligopeptide ABC transporter permease complement(1188363..1189298) Haemophilus influenzae Rd KW20 950091 NP_439280.1 CDS oppB NC_000907.1 1189308 1190228 R similar to GB:U00096 PID:1742033 PID:1787497 PID:1805525; oligopeptide transporter permease complement(1189308..1190228) Haemophilus influenzae Rd KW20 950094 NP_439281.1 CDS oppA NC_000907.1 1190309 1191934 R similar to SP:P06202 GB:X05491 GB:X52093 PID:47802 PID:47808; oligopeptide ABC transporter substrate-binding protein complement(1190309..1191934) Haemophilus influenzae Rd KW20 950086 NP_439282.1 CDS talB NC_000907.1 1192230 1193183 D Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 1192230..1193183 Haemophilus influenzae Rd KW20 950099 NP_439287.1 CDS HI1129 NC_000907.1 1196050 1196505 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1196050..1196505 Haemophilus influenzae Rd KW20 950095 NP_439288.1 CDS mraW NC_000907.1 1196536 1197501 D similar to GB:D10483 SP:P18595 GB:X52063 PID:216497 PID:40850; S-adenosyl-methyltransferase MraW 1196536..1197501 Haemophilus influenzae Rd KW20 950097 NP_439289.1 CDS ftsL NC_000907.1 1197504 1197827 D similar to SP:P22187 GB:K00137 GB:S49802 GB:S49875 GB:X52063; cell division protein 1197504..1197827 Haemophilus influenzae Rd KW20 950098 NP_439290.1 CDS ftsI NC_000907.1 1197840 1199672 D similar to GB:D10483 SP:P04286 GB:K00137 GB:S49802 GB:S49875; penicillin-binding protein 3 1197840..1199672 Haemophilus influenzae Rd KW20 950626 NP_439291.1 CDS murE NC_000907.1 1199682 1201148 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1199682..1201148 Haemophilus influenzae Rd KW20 949983 NP_439292.1 CDS murF NC_000907.1 1201162 1202535 D similar to GB:D10483 SP:P11880 PID:216500 PID:40854 PID:42048; UDP-MurNAc-pentapeptide synthetase 1201162..1202535 Haemophilus influenzae Rd KW20 950620 NP_439293.1 CDS mraY NC_000907.1 1202529 1203611 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1202529..1203611 Haemophilus influenzae Rd KW20 950102 NP_439294.1 CDS murD NC_000907.1 1203734 1205047 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1203734..1205047 Haemophilus influenzae Rd KW20 950103 NP_439295.1 CDS ftsW NC_000907.1 1205069 1206253 D similar to GB:D10483 SP:P16457 GB:M30807 PID:146039 PID:216503; cell division protein 1205069..1206253 Haemophilus influenzae Rd KW20 950104 NP_439296.1 CDS murG NC_000907.1 1206265 1207320 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1206265..1207320 Haemophilus influenzae Rd KW20 949484 NP_439297.1 CDS murC NC_000907.1 1207458 1208885 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1207458..1208885 Haemophilus influenzae Rd KW20 949618 NP_439298.1 CDS ddl NC_000907.1 1208957 1209877 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1208957..1209877 Haemophilus influenzae Rd KW20 950555 NP_439299.1 CDS ftsQ NC_000907.1 1209877 1210641 D similar to GB:D10483 SP:P06136 GB:K02668 GB:X02821 PID:145725; cell division protein 1209877..1210641 Haemophilus influenzae Rd KW20 950106 NP_439300.1 CDS ftsA NC_000907.1 1210660 1211937 D similar to GB:D10483 SP:P06137 GB:K02668 GB:M36531 GB:X02821; cell division protein 1210660..1211937 Haemophilus influenzae Rd KW20 950107 NP_439301.1 CDS ftsZ NC_000907.1 1212021 1213286 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1212021..1213286 Haemophilus influenzae Rd KW20 950290 NP_439302.1 CDS lpxC NC_000907.1 1213325 1214242 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1213325..1214242 Haemophilus influenzae Rd KW20 950276 NP_439303.1 CDS pheA NC_000907.1 1214369 1215526 D similar to SP:Q02286 GB:M74134 GB:X60420 PID:148468 PID:43344; chorismate mutase/prephenate dehydratase 1214369..1215526 Haemophilus influenzae Rd KW20 950108 NP_439304.2 CDS HI1146 NC_000907.1 1215571 1216428 R similar to SP:P33995 GB:Z27094 PID:414888 PID:551341 PID:606144; hypothetical protein complement(1215571..1216428) Haemophilus influenzae Rd KW20 950109 NP_439305.1 CDS ptsN NC_000907.1 1216446 1216940 R similar to GB:D12938 SP:P31222 GB:Z27094 PID:285783 PID:414887; nitrogen regulatory IIA protein complement(1216446..1216940) Haemophilus influenzae Rd KW20 950111 NP_439306.1 CDS HI1148 NC_000907.1 1216943 1217668 R similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140; ABC transporter ATP-binding protein complement(1216943..1217668) Haemophilus influenzae Rd KW20 950112 NP_439307.1 CDS HI1149m NC_000907.1 1217672 1218190 R hypothetical protein complement(1217672..1218190) Haemophilus influenzae Rd KW20 950113 NP_439308.2 CDS HI1150 NC_000907.1 1218171 1218785 R similar to SP:P45397 PID:606138 GB:U00096 PID:1789591; hypothetical protein complement(1218171..1218785) Haemophilus influenzae Rd KW20 950694 NP_439309.1 CDS HI1151 NC_000907.1 1218836 1219372 R similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096; hypothetical protein complement(1218836..1219372) Haemophilus influenzae Rd KW20 949961 NP_439310.1 CDS pmbA NC_000907.1 1219461 1220816 D similar to SP:P24231 GB:X54152 PID:42440 PID:537077 GB:U00096; hypothetical protein 1219461..1220816 Haemophilus influenzae Rd KW20 950115 NP_439311.1 CDS hpt NC_000907.1 1221027 1221566 D Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1221027..1221566 Haemophilus influenzae Rd KW20 950117 NP_439312.1 CDS HI1154 NC_000907.1 1221872 1223194 D similar to GB:U00096 PID:1742823 PID:1742828 PID:1788024; proton glutamate symport protein 1221872..1223194 Haemophilus influenzae Rd KW20 950771 NP_439313.1 CDS nrdG NC_000907.1 1223294 1223761 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(1223294..1223761) Haemophilus influenzae Rd KW20 949759 NP_439314.1 CDS cydC NC_000907.1 1224009 1225739 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane protein/ATP-binding protein complement(1224009..1225739) Haemophilus influenzae Rd KW20 949498 NP_439315.1 CDS cydD NC_000907.1 1225739 1227499 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane protein/ATP-binding protein complement(1225739..1227499) Haemophilus influenzae Rd KW20 949785 NP_439316.1 CDS trxB NC_000907.1 1227571 1228527 R similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096; thioredoxin reductase complement(1227571..1228527) Haemophilus influenzae Rd KW20 950118 NP_439317.2 CDS HI1159m NC_000907.1 1228601 1229459 R contains frameshifts; thioredoxin domain-containing protein complement(join(1228601..1229386,1229385..1229459)) Haemophilus influenzae Rd KW20 950110 NP_439318.1 CDS hemH NC_000907.1 1229539 1230510 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1229539..1230510) Haemophilus influenzae Rd KW20 950120 NP_439319.1 CDS HI1161 NC_000907.1 1230507 1230923 R similar to GB:M24143 SP:P15050 PID:450383 PID:522184 GB:U00096; hypothetical protein complement(1230507..1230923) Haemophilus influenzae Rd KW20 950121 NP_439320.1 CDS HI1162 NC_000907.1 1231372 1231845 R similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546; hypothetical protein complement(1231372..1231845) Haemophilus influenzae Rd KW20 950122 NP_439321.1 CDS HI1163 NC_000907.1 1231849 1234932 R similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977; hypothetical protein complement(1231849..1234932) Haemophilus influenzae Rd KW20 950119 NP_439322.1 CDS ompA NC_000907.1 1235301 1236362 D similar to GB:L20309 SP:P38368; outer membrane protein P5 1235301..1236362 Haemophilus influenzae Rd KW20 950124 NP_439323.2 CDS HI1165 NC_000907.1 1236513 1236836 D similar to PID:2407233; hypothetical protein 1236513..1236836 Haemophilus influenzae Rd KW20 949810 NP_439324.1 CDS hisH NC_000907.1 1236913 1238013 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(1236913..1238013) Haemophilus influenzae Rd KW20 950769 NP_439325.1 CDS serC NC_000907.1 1238101 1239189 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(1238101..1239189) Haemophilus influenzae Rd KW20 949636 NP_439326.1 CDS HI1168 NC_000907.1 1239380 1239724 D similar to GB:U00096 PID:1788317; hypothetical protein 1239380..1239724 Haemophilus influenzae Rd KW20 950127 YP_008530234.1 CDS HI1168a NC_000907.1 1239765 1240331 R hypothetical protein complement(1239765..1240331) Haemophilus influenzae Rd KW20 16830696 YP_008530235.1 CDS HI1169 NC_000907.1 1240331 1241317 R para-aminobenzoate synthase component I complement(1240331..1241317) Haemophilus influenzae Rd KW20 950132 NP_439329.1 CDS trpG NC_000907.1 1241359 1241940 D catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; anthranilate synthase component II 1241359..1241940 Haemophilus influenzae Rd KW20 950129 NP_439330.1 CDS metX NC_000907.1 1242025 1243179 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1242025..1243179 Haemophilus influenzae Rd KW20 950016 NP_439331.1 CDS sprT NC_000907.1 1243518 1243988 D similar to SP:P39902 PID:1208420 PID:882473 GB:U00096 PID:1789313; hypothetical protein 1243518..1243988 Haemophilus influenzae Rd KW20 950125 NP_439332.2 CDS HI1174 NC_000907.1 1244067 1244552 D similar to GB:X15780 PID:1333789; opacity protein 1244067..1244552 Haemophilus influenzae Rd KW20 950130 NP_439333.1 CDS artM NC_000907.1 1245169 1245852 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(1245169..1245852) Haemophilus influenzae Rd KW20 950131 NP_439334.1 CDS artQ NC_000907.1 1245852 1246517 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(1245852..1246517) Haemophilus influenzae Rd KW20 950141 NP_439335.1 CDS artI NC_000907.1 1246521 1247240 R similar to GB:M59210 SP:P49618 PID:387859; arginine ABC transporter substrate-binding protein complement(1246521..1247240) Haemophilus influenzae Rd KW20 950269 NP_439336.1 CDS artP NC_000907.1 1247258 1247989 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding protein complement(1247258..1247989) Haemophilus influenzae Rd KW20 950628 NP_439337.1 CDS gmhA NC_000907.1 1248116 1248700 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(1248116..1248700) Haemophilus influenzae Rd KW20 950026 NP_439340.1 CDS dppF NC_000907.1 1249741 1250724 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding protein complement(1249741..1250724) Haemophilus influenzae Rd KW20 950622 NP_439341.1 CDS dppD NC_000907.1 1250727 1251719 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding protein complement(1250727..1251719) Haemophilus influenzae Rd KW20 950137 NP_439342.1 CDS dppC NC_000907.1 1251729 1252616 R similar to SP:P37315 PID:349227 PID:466681 GB:U00096 PID:1789964; dipeptide ABC transporter permease complement(1251729..1252616) Haemophilus influenzae Rd KW20 950114 NP_439343.2 CDS dppB NC_000907.1 1252631 1253602 R similar to SP:P37316 PID:349226 PID:466682 GB:U00096 PID:1789965; dipeptide ABC transporter permease complement(1252631..1253602) Haemophilus influenzae Rd KW20 950100 NP_439344.1 CDS uvrD NC_000907.1 1253722 1255905 R unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II complement(1253722..1255905) Haemophilus influenzae Rd KW20 950076 NP_439345.1 CDS HI1189 NC_000907.1 1256516 1257151 R similar to PID:1652793; hypothetical protein complement(1256516..1257151) Haemophilus influenzae Rd KW20 950138 NP_439346.1 CDS HI1190 NC_000907.1 1257152 1257577 R similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124; 6-pyruvoyl tetrahydrobiopterin synthase complement(1257152..1257577) Haemophilus influenzae Rd KW20 950142 NP_439348.1 CDS HI1192 NC_000907.1 1258413 1258556 D hypothetical protein 1258413..1258556 Haemophilus influenzae Rd KW20 950139 NP_439349.1 CDS ilvE NC_000907.1 1258603 1259634 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1258603..1259634) Haemophilus influenzae Rd KW20 950143 NP_439350.1 CDS gcvA NC_000907.1 1260108 1261001 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 1260108..1261001 Haemophilus influenzae Rd KW20 950145 NP_439351.1 CDS HI1195m NC_000907.1 1260994 1262085 D RNA 2'-O-ribose methyltransferase 1260994..1262085 Haemophilus influenzae Rd KW20 950147 NP_439352.1 CDS sucC NC_000907.1 1262121 1263290 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1262121..1263290 Haemophilus influenzae Rd KW20 950149 NP_439353.1 CDS sucD NC_000907.1 1263290 1264171 D similar to GB:J01619 SP:P07459 PID:146204 PID:809679 GB:U00096; succinyl-CoA synthetase subunit alpha 1263290..1264171 Haemophilus influenzae Rd KW20 950515 NP_439354.1 CDS HI1198 NC_000907.1 1264292 1264915 D similar to SP:P45847 PID:602960 GB:U00096 PID:1787521; hypothetical protein 1264292..1264915 Haemophilus influenzae Rd KW20 950741 NP_439355.1 CDS HI1199 NC_000907.1 1264963 1266036 D similar to PID:602963 GB:U00096 PID:1787524; hypothetical protein 1264963..1266036 Haemophilus influenzae Rd KW20 950150 NP_439356.1 CDS cysB NC_000907.1 1266047 1267018 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1266047..1267018 Haemophilus influenzae Rd KW20 950152 NP_439357.1 CDS HI1201 NC_000907.1 1267077 1268021 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(1267077..1268021) Haemophilus influenzae Rd KW20 950156 NP_439358.2 CDS HI1202 NC_000907.1 1268132 1268656 D similar to GB:U00096 PID:1788671; hypothetical protein 1268132..1268656 Haemophilus influenzae Rd KW20 950140 NP_439359.1 CDS pta NC_000907.1 1268731 1270866 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(1268731..1270866) Haemophilus influenzae Rd KW20 950151 NP_439360.1 CDS ackA NC_000907.1 1270934 1272139 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1270934..1272139) Haemophilus influenzae Rd KW20 949638 NP_439361.1 CDS HI1205 NC_000907.1 1272354 1272797 D similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632; hypothetical protein 1272354..1272797 Haemophilus influenzae Rd KW20 950166 NP_439362.1 CDS cvpA NC_000907.1 1272884 1273375 D similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096; colicin V production protein 1272884..1273375 Haemophilus influenzae Rd KW20 950153 NP_439363.1 CDS purF NC_000907.1 1273386 1274903 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1273386..1274903 Haemophilus influenzae Rd KW20 950171 NP_439364.1 CDS HI1208 NC_000907.1 1274958 1275848 R similar to GB:L42023 PID:1007092 PID:1221333 PID:1205451 PID:1574138; hypothetical protein complement(1274958..1275848) Haemophilus influenzae Rd KW20 950157 NP_439365.1 CDS argR NC_000907.1 1275848 1276303 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor complement(1275848..1276303) Haemophilus influenzae Rd KW20 950154 NP_439366.1 CDS mdh NC_000907.1 1276510 1277445 D oxidizes malate to oxaloacetate; malate dehydrogenase 1276510..1277445 Haemophilus influenzae Rd KW20 950148 NP_439367.1 CDS lysS NC_000907.1 1277530 1279038 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(1277530..1279038) Haemophilus influenzae Rd KW20 950158 YP_008530236.1 CDS HI1212 NC_000907.1 1279189 1279935 R peptide chain release factor 1 complement(1279189..1279935) Haemophilus influenzae Rd KW20 950159 NP_439369.1 CDS dsbC NC_000907.1 1280420 1281109 D similar to GB:M54884 SP:P21892 PID:147549 PID:887843 GB:U00096; thiol-disulfide interchange protein 1280420..1281109 Haemophilus influenzae Rd KW20 950655 NP_439370.1 CDS recJ NC_000907.1 1281398 1283125 D similar to GB:M54884 SP:P21893 PID:147550 PID:887842 GB:U00096; single-stranded-DNA-specific exonuclease 1281398..1283125 Haemophilus influenzae Rd KW20 950889 NP_439371.2 CDS dsbA NC_000907.1 1283130 1283825 D similar to PID:840949 SP:P50024; thiol-disulfide interchange protein 1283130..1283825 Haemophilus influenzae Rd KW20 950165 NP_439372.1 CDS pfs NC_000907.1 1283822 1284511 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1283822..1284511 Haemophilus influenzae Rd KW20 950160 NP_439373.1 CDS HI1217 NC_000907.1 1284588 1287329 R similar to PID:2764817; transferrin-binding protein complement(1284588..1287329) Haemophilus influenzae Rd KW20 950767 NP_439374.1 CDS lctP NC_000907.1 1287584 1289182 R similar to GB:AE000782; L-lactate permease complement(1287584..1289182) Haemophilus influenzae Rd KW20 950748 NP_439375.2 CDS cmk NC_000907.1 1289456 1290157 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1289456..1290157 Haemophilus influenzae Rd KW20 950461 NP_439376.1 CDS rpsA NC_000907.1 1290233 1291882 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1290233..1291882 Haemophilus influenzae Rd KW20 950163 NP_439377.1 CDS ihfB NC_000907.1 1292005 1292289 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1292005..1292289 Haemophilus influenzae Rd KW20 950562 NP_439378.1 CDS HI1222 NC_000907.1 1292364 1292657 D similar to GB:U00096 PID:1787535; hypothetical protein 1292364..1292657 Haemophilus influenzae Rd KW20 950617 NP_439379.1 CDS HI1223 NC_000907.1 1292657 1293847 D similar to SP:P45576 GB:U00096 PID:2367116; hypothetical protein 1292657..1293847 Haemophilus influenzae Rd KW20 950168 NP_439380.1 CDS pyrF NC_000907.1 1293871 1294563 D OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1293871..1294563 Haemophilus influenzae Rd KW20 950791 NP_439381.1 CDS HI1225 NC_000907.1 1294570 1294890 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1294570..1294890 Haemophilus influenzae Rd KW20 950401 NP_439382.1 CDS HI1225.1 NC_000907.1 1294919 1295614 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(1294919..1295614) Haemophilus influenzae Rd KW20 950792 NP_439383.1 CDS uraA NC_000907.1 1295680 1296924 R similar to GB:X76083 SP:P41006 PID:431231; uracil permease complement(1295680..1296924) Haemophilus influenzae Rd KW20 950172 NP_439384.1 CDS upp NC_000907.1 1297029 1297655 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(1297029..1297655) Haemophilus influenzae Rd KW20 950169 NP_439385.1 CDS dnaX NC_000907.1 1297779 1299845 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(1297779..1299845) Haemophilus influenzae Rd KW20 950174 NP_439386.1 CDS apt NC_000907.1 1299857 1300399 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1299857..1300399) Haemophilus influenzae Rd KW20 950707 NP_439387.1 CDS lpdA NC_000907.1 1300547 1301983 R E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1300547..1301983) Haemophilus influenzae Rd KW20 950173 NP_439388.1 CDS aceF NC_000907.1 1302097 1303800 R similar to GB:D26562 SP:P06959 GB:V01498 PID:434011 PID:473784; dihydrolipoamide acetyltransferase complement(1302097..1303800) Haemophilus influenzae Rd KW20 949836 NP_439389.1 CDS aceE NC_000907.1 1303863 1306523 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(1303863..1306523) Haemophilus influenzae Rd KW20 950116 NP_439390.1 CDS mgsA NC_000907.1 1306823 1307281 D catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1306823..1307281 Haemophilus influenzae Rd KW20 950176 NP_439393.1 CDS dnaK NC_000907.1 1309144 1311051 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1309144..1311051 Haemophilus influenzae Rd KW20 950188 NP_439394.1 CDS dnaJ NC_000907.1 1311102 1312286 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1311102..1312286 Haemophilus influenzae Rd KW20 950178 NP_439395.1 CDS proA NC_000907.1 1312365 1313618 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1312365..1313618) Haemophilus influenzae Rd KW20 950691 NP_439396.1 CDS HI1240 NC_000907.1 1313639 1314301 R similar to GB:L10328 SP:P31432 PID:290496 GB:U00096 PID:1790078; hypothetical protein complement(1313639..1314301) Haemophilus influenzae Rd KW20 950105 NP_439397.1 CDS HI1241 NC_000907.1 1314399 1315199 D hypothetical protein 1314399..1315199 Haemophilus influenzae Rd KW20 950179 NP_439398.1 CDS bcr NC_000907.1 1315231 1316427 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system complement(1315231..1316427) Haemophilus influenzae Rd KW20 949578 NP_439399.1 CDS rsuA NC_000907.1 1316429 1317127 R similar to SP:P33918 PID:405907 GB:U00096 PID:1788510; 16S pseudouridylate 516 synthase complement(1316429..1317127) Haemophilus influenzae Rd KW20 950576 NP_439400.1 CDS HI1244 NC_000907.1 1317218 1317838 R hypothetical protein complement(1317218..1317838) Haemophilus influenzae Rd KW20 950183 NP_439401.1 CDS HI1245 NC_000907.1 1318036 1320306 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 1318036..1320306 Haemophilus influenzae Rd KW20 949562 NP_439402.1 CDS HI1246 NC_000907.1 1320516 1322459 D hypothetical protein 1320516..1322459 Haemophilus influenzae Rd KW20 950184 NP_439403.1 CDS uvrB NC_000907.1 1322490 1324529 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1322490..1324529) Haemophilus influenzae Rd KW20 950196 NP_439404.1 CDS HI1248 NC_000907.1 1325143 1326111 R hypothetical protein complement(1325143..1326111) Haemophilus influenzae Rd KW20 950186 NP_439405.1 CDS HI1249 NC_000907.1 1326114 1326734 R hypothetical protein complement(1326114..1326734) Haemophilus influenzae Rd KW20 950126 NP_439406.1 CDS HI1250 NC_000907.1 1327059 1327364 D hypothetical protein 1327059..1327364 Haemophilus influenzae Rd KW20 950243 NP_439407.1 CDS vapA NC_000907.1 1327375 1327698 D similar to PID:1002991 PID:563265 SP:Q46560; virulence-associated protein A 1327375..1327698 Haemophilus influenzae Rd KW20 950190 NP_439408.1 CDS HI1252 NC_000907.1 1327861 1329531 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1327861..1329531 Haemophilus influenzae Rd KW20 950263 NP_439409.1 CDS HI1253 NC_000907.1 1329551 1329934 D similar to PID:968932 GB:U00096 PID:1787464; hypothetical protein 1329551..1329934 Haemophilus influenzae Rd KW20 950692 NP_439413.1 CDS mfd NC_000907.1 1332180 1335620 D similar to SP:P30958 GB:U00096 PID:1651547 PID:1651549 PID:1787357; transcription-repair coupling factor 1332180..1335620 Haemophilus influenzae Rd KW20 950181 NP_439414.1 CDS HI1259 NC_000907.1 1335673 1337073 R similar to SP:P39099 PID:558912 PID:606173 PID:984379 GB:U00096; serine protease complement(1335673..1337073) Haemophilus influenzae Rd KW20 950193 NP_439415.1 CDS accD NC_000907.1 1337267 1338157 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1337267..1338157 Haemophilus influenzae Rd KW20 950194 NP_439416.1 CDS folC NC_000907.1 1338150 1339463 D similar to GB:M68934 SP:P08192 GB:M32445 PID:146009 PID:146020; folylpolyglutamate synthase/dihydrofolate synthase 1338150..1339463 Haemophilus influenzae Rd KW20 950205 NP_439417.2 CDS sanA NC_000907.1 1339751 1340431 R similar to SP:P33017 PID:405877 PID:1161522 GB:U00096 PID:1788466; hypothetical protein complement(1339751..1340431) Haemophilus influenzae Rd KW20 950206 NP_439418.1 CDS metX NC_000907.1 1340589 1341665 D Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 1340589..1341665 Haemophilus influenzae Rd KW20 950208 NP_439419.1 CDS gyrA NC_000907.1 1341719 1344361 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(1341719..1344361) Haemophilus influenzae Rd KW20 950199 NP_439420.1 CDS HI1265 NC_000907.1 1344944 1346707 R similar to GB:U00096 SP:P75838 PID:1787133; hypothetical protein complement(1344944..1346707) Haemophilus influenzae Rd KW20 950187 NP_439421.1 CDS HI1266 NC_000907.1 1346844 1347230 R hypothetical protein complement(1346844..1347230) Haemophilus influenzae Rd KW20 950198 NP_439425.1 CDS HI1272 NC_000907.1 1348468 1349259 D similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024; ABC transporter ATP-binding protein 1348468..1349259 Haemophilus influenzae Rd KW20 950689 NP_439426.1 CDS HI1273 NC_000907.1 1349256 1350062 D similar to PID:1816658; hypothetical protein 1349256..1350062 Haemophilus influenzae Rd KW20 950164 NP_439427.1 CDS HI1274 NC_000907.1 1350114 1350830 D similar to PID:1208973 GB:U00096 SP:Q47677 PID:1552782 PID:1786406; hydroxyacylglutathione hydrolase 1350114..1350830 Haemophilus influenzae Rd KW20 950207 NP_439428.1 CDS tehB NC_000907.1 1350886 1351746 R with TehA confers resistance to tellurite; tellurite resistance protein TehB complement(1350886..1351746) Haemophilus influenzae Rd KW20 949980 NP_439429.1 CDS metG NC_000907.1 1351859 1353907 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1351859..1353907) Haemophilus influenzae Rd KW20 949809 NP_439430.2 CDS mrp NC_000907.1 1354058 1355170 D similar to SP:P21590 GB:U00007 GB:X55791 PID:405896 PID:42017; ATPase 1354058..1355170 Haemophilus influenzae Rd KW20 950197 NP_439431.1 CDS HI1278 NC_000907.1 1355217 1355879 R similar to GB:D17743 SP:P46072 PID:517169; NAD(P)H-flavin oxidoreductase complement(1355217..1355879) Haemophilus influenzae Rd KW20 950210 NP_439432.1 CDS neuA NC_000907.1 1355984 1356670 D similar to GB:M95053 GB:X78068 GB:U04328 PID:460146 PID:520734; acylneuraminate cytidylyltransferase 1355984..1356670 Haemophilus influenzae Rd KW20 950022 NP_439434.2 CDS HI1282 NC_000907.1 1358656 1359111 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1358656..1359111 Haemophilus influenzae Rd KW20 950221 NP_439435.1 CDS nusA NC_000907.1 1359128 1360615 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1359128..1360615 Haemophilus influenzae Rd KW20 950214 NP_439436.1 CDS infB NC_000907.1 1360627 1363116 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1360627..1363116 Haemophilus influenzae Rd KW20 950215 NP_439437.1 CDS hsdR NC_000907.1 1363195 1366362 R similar to PID:1685100; type I restriction enzyme complement(1363195..1366362) Haemophilus influenzae Rd KW20 950228 NP_439438.1 CDS hsdS NC_000907.1 1366454 1367833 R similar to PID:1685099; type I restriction/modification specificity protein complement(1366454..1367833) Haemophilus influenzae Rd KW20 950231 NP_439439.2 CDS hsdM NC_000907.1 1367826 1369556 R similar to PID:1679866; type I modification enzyme complement(1367826..1369556) Haemophilus influenzae Rd KW20 950217 NP_439440.1 CDS rbfA NC_000907.1 1369672 1370058 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1369672..1370058 Haemophilus influenzae Rd KW20 950218 NP_439441.1 CDS truB NC_000907.1 1370058 1370996 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1370058..1370996 Haemophilus influenzae Rd KW20 950222 NP_439442.1 CDS tyrA NC_000907.1 1371056 1372189 D catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 1371056..1372189 Haemophilus influenzae Rd KW20 950220 NP_439443.1 CDS queF NC_000907.1 1372222 1373061 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(1372222..1373061) Haemophilus influenzae Rd KW20 949405 NP_439444.1 CDS HI1292 NC_000907.1 1373188 1373973 R hypothetical protein complement(1373188..1373973) Haemophilus influenzae Rd KW20 949593 NP_439445.1 CDS HI1293 NC_000907.1 1373964 1374344 R similar to PID:882706 GB:U00096 SP:Q46926 PID:1789176; hypothetical protein complement(1373964..1374344) Haemophilus influenzae Rd KW20 950226 NP_439446.2 CDS HI1295 NC_000907.1 1374341 1375534 R similar to PID:882705 GB:U00096 PID:1789175; selenocysteine lyase complement(1374341..1375534) Haemophilus influenzae Rd KW20 950232 NP_439447.2 CDS HI1296 NC_000907.1 1375488 1376003 R similar to SP:P29769; nuclease complement(1375488..1376003) Haemophilus influenzae Rd KW20 950236 NP_439448.1 CDS HI1297 NC_000907.1 1376139 1376561 D similar to SP:P33372 PID:405872 GB:U00096 PID:1788463; hypothetical protein 1376139..1376561 Haemophilus influenzae Rd KW20 950233 NP_439449.1 CDS HI1298 NC_000907.1 1376580 1377275 D similar to SP:P33373 PID:405873 GB:U00096 PID:1788464; hypothetical protein 1376580..1377275 Haemophilus influenzae Rd KW20 950227 NP_439451.1 CDS HI1300 NC_000907.1 1378846 1380789 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1378846..1380789 Haemophilus influenzae Rd KW20 950128 NP_439452.1 CDS HI1301 NC_000907.1 1380817 1381506 R similar to PID:1513236; carbonic anhydrase complement(1380817..1381506) Haemophilus influenzae Rd KW20 950229 NP_439453.2 CDS asnC NC_000907.1 1381582 1382985 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1381582..1382985) Haemophilus influenzae Rd KW20 950195 NP_439454.2 CDS ribH NC_000907.1 1383211 1383684 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1383211..1383684 Haemophilus influenzae Rd KW20 949500 NP_439455.1 CDS nusB NC_000907.1 1383688 1384122 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1383688..1384122 Haemophilus influenzae Rd KW20 950225 NP_439456.1 CDS thiL NC_000907.1 1384139 1385176 D similar to GB:U00096 SP:P77785 PID:1773101 PID:1786619 PID:2329840; thiamin-monophosphate kinase 1384139..1385176 Haemophilus influenzae Rd KW20 950230 NP_439457.1 CDS pgpA NC_000907.1 1385173 1385664 D similar to GB:U00096 PID:1773102 PID:1786620 PID:2329841; phosphatidylglycerophosphatase A 1385173..1385664 Haemophilus influenzae Rd KW20 950237 NP_439458.1 CDS HI1307 NC_000907.1 1385661 1386293 D similar to GB:U00096 SP:P75693 PID:1657525 PID:1786522; hypothetical protein 1385661..1386293 Haemophilus influenzae Rd KW20 950239 NP_439459.1 CDS dapB NC_000907.1 1386310 1387122 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1386310..1387122 Haemophilus influenzae Rd KW20 950240 NP_439460.1 CDS HI1309 NC_000907.1 1387117 1387365 R similar to SP:P37910 GB:U00096 PID:1788568; hypothetical protein complement(1387117..1387365) Haemophilus influenzae Rd KW20 950234 NP_439461.1 CDS HI1310 NC_000907.1 1387390 1388151 D hypothetical protein 1387390..1388151 Haemophilus influenzae Rd KW20 949509 NP_439462.1 CDS pheS NC_000907.1 1388300 1389289 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1388300..1389289 Haemophilus influenzae Rd KW20 950073 NP_439463.1 CDS pheT NC_000907.1 1389323 1391710 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1389323..1391710 Haemophilus influenzae Rd KW20 950235 NP_439464.1 CDS ihfA NC_000907.1 1391712 1392002 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1391712..1392002 Haemophilus influenzae Rd KW20 949629 NP_439465.1 CDS nlpC NC_000907.1 1392055 1392540 D similar to GB:M14031 SP:P23898 PID:145446 GB:U00096 PID:1742788; lipoprotein 1392055..1392540 Haemophilus influenzae Rd KW20 949594 NP_439466.2 CDS HI1315 NC_000907.1 1392718 1393023 D hypothetical protein 1392718..1393023 Haemophilus influenzae Rd KW20 950581 NP_439467.2 CDS HI1316 NC_000907.1 1393010 1393996 D sulfatase-like protein 1393010..1393996 Haemophilus influenzae Rd KW20 950238 NP_439468.1 CDS HI1317 NC_000907.1 1394078 1394893 D similar to GB:U00096 SP:P39173 PID:1736408 PID:1742898 PID:1788080; hypothetical protein 1394078..1394893 Haemophilus influenzae Rd KW20 950209 NP_439469.1 CDS infC NC_000907.1 1395026 1395568 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1395026..1395568 Haemophilus influenzae Rd KW20 950242 NP_439470.1 CDS rpmI NC_000907.1 1395779 1395976 D 50S ribosomal protein L35 1395779..1395976 Haemophilus influenzae Rd KW20 950241 NP_439471.1 CDS rplT NC_000907.1 1396043 1396396 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1396043..1396396 Haemophilus influenzae Rd KW20 950247 NP_439472.1 CDS recB NC_000907.1 1396509 1400144 D similar to SP:P08394 GB:X04581 GB:X04582 PID:42682 PID:763090; exodeoxyribonuclease V subunit beta 1396509..1400144 Haemophilus influenzae Rd KW20 950246 NP_439473.1 CDS recD NC_000907.1 1400144 1402066 D similar to SP:P04993 GB:X04581 GB:X04582 PID:42683 PID:42691; exodeoxyribonuclease V subunit alpha 1400144..1402066 Haemophilus influenzae Rd KW20 950249 NP_439474.1 CDS HI1323 NC_000907.1 1402135 1402581 R similar to SP:P45569 GB:U00096 PID:1787190; hypothetical protein complement(1402135..1402581) Haemophilus influenzae Rd KW20 950258 NP_439475.1 CDS HI1324 NC_000907.1 1402678 1404483 D similar to GB:D00863 SP:P36772 PID:402504; lon protease 1402678..1404483 Haemophilus influenzae Rd KW20 950250 NP_439476.1 CDS fabA NC_000907.1 1404652 1405185 D catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1404652..1405185 Haemophilus influenzae Rd KW20 950257 NP_439477.1 CDS HI1326 NC_000907.1 1405419 1406147 D hypothetical protein 1405419..1406147 Haemophilus influenzae Rd KW20 950251 NP_439478.1 CDS HI1327 NC_000907.1 1406144 1406281 D hypothetical protein 1406144..1406281 Haemophilus influenzae Rd KW20 950255 NP_439479.1 CDS rpsO NC_000907.1 1406417 1406686 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1406417..1406686 Haemophilus influenzae Rd KW20 950244 NP_439482.1 CDS dacB NC_000907.1 1407458 1408897 R penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase complement(1407458..1408897) Haemophilus influenzae Rd KW20 950252 NP_439483.1 CDS greA NC_000907.1 1409061 1409537 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1409061..1409537 Haemophilus influenzae Rd KW20 950254 NP_439484.1 CDS yhbY NC_000907.1 1409576 1409875 R contains RNA-binding domains; monomeric; similar to SP:P42550 PID:606118 GB:U00096 PID:1789570; hypothetical protein complement(1409576..1409875) Haemophilus influenzae Rd KW20 949671 NP_439485.1 CDS rrmJ NC_000907.1 1410002 1410631 D Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 1410002..1410631 Haemophilus influenzae Rd KW20 950794 NP_439486.1 CDS ftsH NC_000907.1 1410722 1412629 D similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116; cell division protein 1410722..1412629 Haemophilus influenzae Rd KW20 950795 NP_439487.1 CDS folP-1 NC_000907.1 1412741 1413568 D similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777; dihydropteroate synthase 1412741..1413568 Haemophilus influenzae Rd KW20 950701 NP_439488.1 CDS glmM NC_000907.1 1413606 1414943 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1413606..1414943 Haemophilus influenzae Rd KW20 950893 NP_439489.1 CDS HI1338 NC_000907.1 1415002 1415496 D similar to GB:U00096 PID:1788681; hypothetical protein 1415002..1415496 Haemophilus influenzae Rd KW20 950260 NP_439490.1 CDS HI1339 NC_000907.1 1415698 1416087 D hypothetical protein 1415698..1416087 Haemophilus influenzae Rd KW20 950818 NP_439491.1 CDS HI1340 NC_000907.1 1416165 1417490 R similar to PID:882689 GB:U00096 SP:Q46920 PID:1789158; hypothetical protein complement(1416165..1417490) Haemophilus influenzae Rd KW20 950814 NP_439492.1 CDS HI1341 NC_000907.1 1417617 1418228 R hemoglobin-binding protein complement(1417617..1418228) Haemophilus influenzae Rd KW20 950616 NP_439493.1 CDS HI1343 NC_000907.1 1418131 1418847 R hypothetical protein complement(1418131..1418847) Haemophilus influenzae Rd KW20 949643 NP_439494.1 CDS HI1342 NC_000907.1 1418744 1420123 D similar to SP:P43672 GB:U00096 PID:1787182 PID:2251144; ABC transporter ATP-binding protein 1418744..1420123 Haemophilus influenzae Rd KW20 950264 NP_439495.1 CDS potD NC_000907.1 1420204 1421343 R similar to PID:1142681; spermidine/putrescine ABC transporter substrate-binding protein complement(1420204..1421343) Haemophilus influenzae Rd KW20 950266 NP_439496.1 CDS potC NC_000907.1 1421416 1422159 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1421416..1422159) Haemophilus influenzae Rd KW20 950267 NP_439497.1 CDS potB NC_000907.1 1422185 1423045 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1422185..1423045) Haemophilus influenzae Rd KW20 950272 NP_439498.2 CDS potA NC_000907.1 1423029 1424177 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1423029..1424177) Haemophilus influenzae Rd KW20 950268 NP_439499.1 CDS pepT NC_000907.1 1424443 1425681 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1424443..1425681 Haemophilus influenzae Rd KW20 950265 NP_439500.1 CDS HI1349 NC_000907.1 1426245 1426727 R similar to PID:1652428; hypothetical protein complement(1426245..1426727) Haemophilus influenzae Rd KW20 950182 NP_439501.1 CDS cdd NC_000907.1 1427001 1427879 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1427001..1427879 Haemophilus influenzae Rd KW20 950271 NP_439502.1 CDS HI1351 NC_000907.1 1427922 1428887 R similar to GB:U00096 PID:1788178; hypothetical protein complement(1427922..1428887) Haemophilus influenzae Rd KW20 950443 NP_439503.1 CDS putP NC_000907.1 1428884 1430398 R proline permease; similar to GB:D32069 PID:509694 PID:913690; sodium/proline symporter complement(1428884..1430398) Haemophilus influenzae Rd KW20 950133 NP_439504.1 CDS cafA NC_000907.1 1430514 1431989 D involved in the processing of the 5'end of 16S rRNA; ribonuclease G 1430514..1431989 Haemophilus influenzae Rd KW20 950270 NP_439505.1 CDS glnS NC_000907.1 1432409 1434082 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1432409..1434082 Haemophilus influenzae Rd KW20 950274 NP_439506.1 CDS HI1355 NC_000907.1 1434148 1434612 D similar to GB:U00096 PID:1787429; hypothetical protein 1434148..1434612 Haemophilus influenzae Rd KW20 950283 NP_439507.1 CDS malQ NC_000907.1 1434674 1436773 D similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096; 4-alpha-glucanotransferase 1434674..1436773 Haemophilus influenzae Rd KW20 950287 NP_439508.1 CDS glgB NC_000907.1 1436783 1438975 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 1436783..1438975 Haemophilus influenzae Rd KW20 950275 NP_439509.1 CDS glgX NC_000907.1 1439071 1441050 D similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096; glycogen operon protein 1439071..1441050 Haemophilus influenzae Rd KW20 949470 NP_439510.1 CDS glgC NC_000907.1 1441040 1442374 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1441040..1442374 Haemophilus influenzae Rd KW20 950593 NP_439511.1 CDS glgA NC_000907.1 1442482 1443912 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1442482..1443912 Haemophilus influenzae Rd KW20 950277 NP_439512.1 CDS HI1361 NC_000907.1 1444158 1446623 D similar to GB:J03966 SP:P13031 GB:M22368 GB:X16931 PID:146146; hypothetical protein 1444158..1446623 Haemophilus influenzae Rd KW20 950286 NP_439513.1 CDS pntA NC_000907.1 1446885 1448423 D forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1446885..1448423 Haemophilus influenzae Rd KW20 950278 NP_439514.1 CDS pntB NC_000907.1 1448434 1449858 D catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1448434..1449858 Haemophilus influenzae Rd KW20 950280 NP_439515.1 CDS HI1364 NC_000907.1 1449976 1450842 R similar to SP:P37641 PID:466658 GB:U00096 PID:1789938; transcriptional regulator complement(1449976..1450842) Haemophilus influenzae Rd KW20 950273 NP_439516.1 CDS topA NC_000907.1 1450938 1453544 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1450938..1453544 Haemophilus influenzae Rd KW20 950025 NP_439517.1 CDS acpD NC_000907.1 1453620 1454204 R similar to GB:U00096 PID:1742298 PID:1742303 PID:1787680; acyl carrier protein phosphodiesterase complement(1453620..1454204) Haemophilus influenzae Rd KW20 950279 NP_439518.1 CDS thrS NC_000907.1 1454489 1456420 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1454489..1456420 Haemophilus influenzae Rd KW20 950281 NP_439519.1 CDS HI1368 NC_000907.1 1456539 1459319 R similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451; zinc protease complement(1456539..1459319) Haemophilus influenzae Rd KW20 950673 NP_439520.1 CDS HI1369 NC_000907.1 1459423 1461942 R similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771; hypothetical protein complement(1459423..1461942) Haemophilus influenzae Rd KW20 950892 NP_439521.1 CDS mopI NC_000907.1 1461986 1462195 R similar to GB:M17157 SP:P04952 SP:P08854 GB:M17158 GB:X04982; molybdenum-pterin binding protein complement(1461986..1462195) Haemophilus influenzae Rd KW20 950284 NP_439522.1 CDS HI1371 NC_000907.1 1462303 1462632 R similar to GB:L05610 SP:P45573 PID:145087; dissimilatory sulfite reductase, desulfoviridin subunit gamma complement(1462303..1462632) Haemophilus influenzae Rd KW20 950285 NP_439523.1 CDS HI1371.1 NC_000907.1 1462634 1463575 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1462634..1463575) Haemophilus influenzae Rd KW20 950672 NP_439524.2 CDS kicB NC_000907.1 1463725 1465059 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1463725..1465059 Haemophilus influenzae Rd KW20 950891 NP_439525.1 CDS kicA NC_000907.1 1465106 1465837 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1465106..1465837 Haemophilus influenzae Rd KW20 950288 NP_439526.1 CDS mukB NC_000907.1 1465837 1470369 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1465837..1470369 Haemophilus influenzae Rd KW20 950289 NP_439527.1 CDS HI1375 NC_000907.1 1470440 1471348 D hypothetical protein 1470440..1471348 Haemophilus influenzae Rd KW20 950817 NP_439528.1 CDS HI1376 NC_000907.1 1471351 1472226 D hypothetical protein 1471351..1472226 Haemophilus influenzae Rd KW20 950804 NP_439529.1 CDS sbcB NC_000907.1 1472239 1473660 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1472239..1473660 Haemophilus influenzae Rd KW20 950828 NP_439530.1 CDS phoR NC_000907.1 1474351 1475628 R similar to SP:P08400 GB:X04704 PID:581188 GB:U00096 PID:1657596; phosphate regulon sensor protein PhoR complement(1474351..1475628) Haemophilus influenzae Rd KW20 950291 NP_439531.1 CDS phoB NC_000907.1 1475625 1476320 R similar to SP:P08402 GB:X04026 PID:42388 GB:U00096 PID:1657595; phosphate regulon transcriptional regulatory protein PhoB complement(1475625..1476320) Haemophilus influenzae Rd KW20 950671 NP_439533.1 CDS pstA NC_000907.1 1477193 1478041 R similar to GB:L10328 SP:P07654 GB:K01992 GB:X02723 PID:147258; phosphate ABC transporter permease complement(1477193..1478041) Haemophilus influenzae Rd KW20 950294 NP_439534.1 CDS pstC NC_000907.1 1478043 1478990 R similar to GB:L10328 SP:P07653 GB:K01992 GB:X02723 PID:147257; phosphate ABC transporter permease complement(1478043..1478990) Haemophilus influenzae Rd KW20 950295 NP_439535.1 CDS pstS NC_000907.1 1479081 1480084 R phosphate ABC transporter substrate-binding protein complement(join(1479081..1480076,1480076..1480084)) Haemophilus influenzae Rd KW20 950702 NP_439536.1 CDS rsgA NC_000907.1 1480541 1481089 D similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567; ferritin like protein 1 1480541..1481089 Haemophilus influenzae Rd KW20 950297 NP_439537.1 CDS rsgA NC_000907.1 1481105 1481602 D similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567; ferritin 1481105..1481602 Haemophilus influenzae Rd KW20 950298 NP_439538.1 CDS HI1386 NC_000907.1 1481976 1482422 D hypothetical protein 1481976..1482422 Haemophilus influenzae Rd KW20 950299 NP_439539.1 CDS trpE NC_000907.1 1482528 1484084 D with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1482528..1484084 Haemophilus influenzae Rd KW20 950300 NP_439540.1 CDS trpG NC_000907.1 1484097 1484678 D TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1484097..1484678 Haemophilus influenzae Rd KW20 950293 NP_439541.1 CDS HI1388.1 NC_000907.1 1484727 1485113 D hypothetical protein 1484727..1485113 Haemophilus influenzae Rd KW20 950703 NP_439542.1 CDS trpD NC_000907.1 1485166 1486167 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1485166..1486167 Haemophilus influenzae Rd KW20 950894 NP_439543.1 CDS trpC NC_000907.1 1486204 1487637 D monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1486204..1487637 Haemophilus influenzae Rd KW20 950301 YP_008530237.1 CDS hybG NC_000907.1 1487699 1487971 D hydrogenase 2 accessory protein 1487699..1487971 Haemophilus influenzae Rd KW20 950155 NP_439545.1 CDS valS NC_000907.1 1488005 1490869 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1488005..1490869) Haemophilus influenzae Rd KW20 950584 NP_439546.1 CDS hindIIIM NC_000907.1 1490870 1491799 R similar to GB:L15391 PID:1574226; modification methylase complement(1490870..1491799) Haemophilus influenzae Rd KW20 950302 NP_439547.1 CDS hindIIIR NC_000907.1 1491780 1492682 R similar to GB:L15391 PID:1574230; type II restriction endonuclease complement(1491780..1492682) Haemophilus influenzae Rd KW20 950303 NP_439548.1 CDS HI1394 NC_000907.1 1492630 1493001 R similar to PID:887850 GB:U00096 SP:Q46828 PID:1789267; hypothetical protein complement(1492630..1493001) Haemophilus influenzae Rd KW20 950304 NP_439550.1 CDS holC NC_000907.1 1493866 1494300 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(1493866..1494300) Haemophilus influenzae Rd KW20 950308 NP_439551.1 CDS fumC NC_000907.1 1494535 1495929 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1494535..1495929 Haemophilus influenzae Rd KW20 950314 NP_439552.1 CDS HI1399 NC_000907.1 1496057 1496665 D hypothetical protein 1496057..1496665 Haemophilus influenzae Rd KW20 950317 NP_439553.1 CDS HI1400 NC_000907.1 1496764 1497588 R similar to GB:U00096 PID:1787520; hypothetical protein complement(1496764..1497588) Haemophilus influenzae Rd KW20 950717 NP_439554.1 CDS pyrD NC_000907.1 1497588 1498607 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(1497588..1498607) Haemophilus influenzae Rd KW20 950325 NP_439556.1 CDS yhxB NC_000907.1 1499076 1499624 R tail fiber protein/phosphomannomutase complement(1499076..1499624) Haemophilus influenzae Rd KW20 950856 NP_439557.1 CDS HI1405 NC_000907.1 1500122 1501222 R hypothetical protein complement(1500122..1501222) Haemophilus influenzae Rd KW20 950333 NP_439558.1 CDS HI1406 NC_000907.1 1501283 1501639 R hypothetical protein complement(1501283..1501639) Haemophilus influenzae Rd KW20 950830 NP_439559.1 CDS HI1407 NC_000907.1 1502127 1503470 R similar to GB:L10330 PID:437700; plasmid RP4 TraN-like protein complement(1502127..1503470) Haemophilus influenzae Rd KW20 950320 NP_439560.1 CDS HI1409 NC_000907.1 1503394 1504704 R hypothetical protein complement(1503394..1504704) Haemophilus influenzae Rd KW20 950321 NP_439561.1 CDS HI1410 NC_000907.1 1504706 1505890 R terminase large subunit-like protein complement(1504706..1505890) Haemophilus influenzae Rd KW20 950727 NP_439562.1 CDS HI1411 NC_000907.1 1506035 1506550 R similar to SP:Q38627 PID:522116; terminase small subunit complement(1506035..1506550) Haemophilus influenzae Rd KW20 950482 NP_439563.1 CDS HI1412 NC_000907.1 1506560 1507081 R similar to SP:P21417 PID:1196685; hypothetical protein complement(1506560..1507081) Haemophilus influenzae Rd KW20 950722 NP_439564.1 CDS HI1413 NC_000907.1 1507209 1507490 R hypothetical protein complement(1507209..1507490) Haemophilus influenzae Rd KW20 949414 NP_439565.1 CDS HI1414 NC_000907.1 1507402 1507677 R hypothetical protein complement(1507402..1507677) Haemophilus influenzae Rd KW20 950322 NP_439566.1 CDS HI1415 NC_000907.1 1507670 1508272 R hypothetical protein complement(1507670..1508272) Haemophilus influenzae Rd KW20 950713 NP_439567.1 CDS HI1416 NC_000907.1 1508241 1508597 R hypothetical protein complement(1508241..1508597) Haemophilus influenzae Rd KW20 950758 NP_439568.2 CDS HI1418 NC_000907.1 1509035 1509601 R hypothetical protein complement(1509035..1509601) Haemophilus influenzae Rd KW20 950323 NP_439569.1 CDS HI1419 NC_000907.1 1509962 1510261 D hypothetical protein 1509962..1510261 Haemophilus influenzae Rd KW20 949900 NP_439570.1 CDS HI1420 NC_000907.1 1510258 1510551 D hypothetical protein 1510258..1510551 Haemophilus influenzae Rd KW20 950760 NP_439571.1 CDS HI1422 NC_000907.1 1511013 1511588 D hypothetical protein 1511013..1511588 Haemophilus influenzae Rd KW20 949966 NP_439572.1 CDS HI1423 NC_000907.1 1511874 1512158 D hypothetical protein 1511874..1512158 Haemophilus influenzae Rd KW20 950324 NP_439573.1 CDS HI1424 NC_000907.1 1512159 1513073 R similar to SP:P10487 GB:D90039 SP:P16470 GB:AB027308 GB:AB027308; integrase/recombinase complement(1512159..1513073) Haemophilus influenzae Rd KW20 950326 NP_439574.1 CDS fnr NC_000907.1 1513585 1514358 D Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1513585..1514358 Haemophilus influenzae Rd KW20 950327 NP_439575.2 CDS HI1426 NC_000907.1 1514479 1515408 D with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1514479..1515408 Haemophilus influenzae Rd KW20 950328 NP_439576.1 CDS HI1427 NC_000907.1 1515608 1516444 D hypothetical protein 1515608..1516444 Haemophilus influenzae Rd KW20 950330 NP_439577.1 CDS purN NC_000907.1 1516529 1517167 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(1516529..1517167) Haemophilus influenzae Rd KW20 950331 NP_439578.1 CDS purM NC_000907.1 1517222 1518256 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(1517222..1518256) Haemophilus influenzae Rd KW20 950335 NP_439579.1 CDS HI1430 NC_000907.1 1518436 1519194 D similar to GB:U00096 PID:1787820; short chain dehydrogenase/reductase 1518436..1519194 Haemophilus influenzae Rd KW20 950332 NP_439580.1 CDS trpB NC_000907.1 1519211 1520404 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1519211..1520404 Haemophilus influenzae Rd KW20 950336 NP_439581.1 CDS trpA NC_000907.1 1520404 1521210 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1520404..1521210 Haemophilus influenzae Rd KW20 950337 NP_439582.1 CDS usg1 NC_000907.1 1521348 1522301 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(1521348..1522301) Haemophilus influenzae Rd KW20 950338 NP_439583.1 CDS ybaK NC_000907.1 1522360 1522836 D contains a C-type lectin fold; similar to prolyl-tRNA synthetases; similar to GB:L23802 SP:P36922 PID:388109; hypothetical protein 1522360..1522836 Haemophilus influenzae Rd KW20 949657 NP_439584.1 CDS cspD NC_000907.1 1522993 1523211 R similar to SP:P24245 GB:U00096 PID:1651400 PID:1787107; cold shock-like protein complement(1522993..1523211) Haemophilus influenzae Rd KW20 949903 NP_439585.2 CDS HI1434.2 NC_000907.1 1523361 1523519 R similar to GB:U00096 PID:1788113; hypothetical protein complement(1523361..1523519) Haemophilus influenzae Rd KW20 949916 NP_439587.1 CDS HI1436 NC_000907.1 1524226 1524546 R similar to PID:882688 GB:U00096 PID:882687; hypothetical protein complement(1524226..1524546) Haemophilus influenzae Rd KW20 950784 NP_439589.1 CDS xseB NC_000907.1 1526179 1526433 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1526179..1526433 Haemophilus influenzae Rd KW20 950341 NP_439590.1 CDS ispA NC_000907.1 1526433 1527320 D similar to GB:D00694 SP:P22939 PID:216584 GB:U00096 PID:1773105; geranyltranstransferase 1526433..1527320 Haemophilus influenzae Rd KW20 950833 NP_439591.1 CDS dxs NC_000907.1 1527362 1529239 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1527362..1529239 Haemophilus influenzae Rd KW20 950315 NP_439592.1 CDS sspB NC_000907.1 1529275 1529727 R similar to GB:M69028 SP:P25663 GB:X05088 PID:147872 PID:42999; ClpXP protease specificity-enhancing factor complement(1529275..1529727) Haemophilus influenzae Rd KW20 950343 NP_439593.1 CDS sspA NC_000907.1 1529727 1530365 R similar to SP:P31784 PID:241868; stringent starvation protein A complement(1529727..1530365) Haemophilus influenzae Rd KW20 950832 NP_439594.1 CDS rpsI NC_000907.1 1530546 1530938 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(1530546..1530938) Haemophilus influenzae Rd KW20 950342 NP_439595.1 CDS rplM NC_000907.1 1530955 1531383 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(1530955..1531383) Haemophilus influenzae Rd KW20 950831 NP_439596.1 CDS metF NC_000907.1 1531847 1532725 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 1531847..1532725 Haemophilus influenzae Rd KW20 950344 NP_439597.1 CDS bioD NC_000907.1 1532814 1533542 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1532814..1533542) Haemophilus influenzae Rd KW20 950720 NP_439598.1 CDS HI1446 NC_000907.1 1533645 1533968 R similar to GB:U00096 PID:1787427; hypothetical protein complement(1533645..1533968) Haemophilus influenzae Rd KW20 950564 NP_439599.1 CDS folE NC_000907.1 1533972 1534628 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(1533972..1534628) Haemophilus influenzae Rd KW20 950345 NP_439600.1 CDS moeA NC_000907.1 1534766 1535980 D similar to GB:M21151 SP:P12281 PID:145539 GB:U00096 PID:1651376; molybdopterin biosynthesis protein 1534766..1535980 Haemophilus influenzae Rd KW20 950719 NP_439601.1 CDS moeB NC_000907.1 1535984 1536715 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1535984..1536715 Haemophilus influenzae Rd KW20 950565 NP_439602.1 CDS HI1450 NC_000907.1 1536782 1537105 D highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1536782..1537105 Haemophilus influenzae Rd KW20 950346 NP_439603.1 CDS HI1452 NC_000907.1 1537173 1537760 R hypothetical protein complement(1537173..1537760) Haemophilus influenzae Rd KW20 950785 NP_439604.1 CDS purL NC_000907.1 1537998 1538468 R similar to GB:AL009126; phosphoribosylformylglycinamidine synthase complement(1537998..1538468) Haemophilus influenzae Rd KW20 950347 NP_439605.1 CDS HI1454 NC_000907.1 1538510 1539151 R similar to SP:P45706 PID:870925 PID:1405449 GB:AL009126; hypothetical protein complement(1538510..1539151) Haemophilus influenzae Rd KW20 950340 NP_439606.1 CDS msrA NC_000907.1 1539163 1540224 R this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase subunits A/B complement(1539163..1540224) Haemophilus influenzae Rd KW20 950358 NP_439607.2 CDS HI1456 NC_000907.1 1540419 1540868 R hypothetical protein complement(1540419..1540868) Haemophilus influenzae Rd KW20 950348 NP_439608.1 CDS HI1457 NC_000907.1 1540879 1541415 R similar to PID:2367659; opacity protein complement(1540879..1541415) Haemophilus influenzae Rd KW20 950146 NP_439610.2 CDS HI1459 NC_000907.1 1542231 1542776 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor complement(1542231..1542776) Haemophilus influenzae Rd KW20 950350 NP_439611.1 CDS HI1462 NC_000907.1 1544081 1545445 D similar to GB:U00096 SP:P77211 PID:1778487 PID:1786785; hypothetical protein 1544081..1545445 Haemophilus influenzae Rd KW20 950787 NP_439612.2 CDS HI1462.1 NC_000907.1 1545523 1545912 R hypothetical protein complement(1545523..1545912) Haemophilus influenzae Rd KW20 950572 NP_439613.1 CDS HI1462.2 NC_000907.1 1546114 1546608 R similar to GB:U00096 PID:1788681; hypothetical protein complement(1546114..1546608) Haemophilus influenzae Rd KW20 950352 NP_439614.1 CDS glmM NC_000907.1 1546667 1548004 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1546667..1548004) Haemophilus influenzae Rd KW20 950567 NP_439615.1 CDS folP-2 NC_000907.1 1548042 1548869 R similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777; dihydropteroate synthase complement(1548042..1548869) Haemophilus influenzae Rd KW20 950351 NP_439616.1 CDS HI1465 NC_000907.1 1548981 1550126 R similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116; cell division FtsH-like protein complement(1548981..1550126) Haemophilus influenzae Rd KW20 950570 NP_439618.1 CDS HI1467 NC_000907.1 1552525 1554294 D similar to SP:Q50614 PID:1483552; ABC transporter ATP-binding protein 1552525..1554294 Haemophilus influenzae Rd KW20 950646 NP_439619.1 CDS rpsO NC_000907.1 1554432 1554701 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1554432..1554701) Haemophilus influenzae Rd KW20 950650 NP_439621.1 CDS HI1470 NC_000907.1 1555042 1555803 R similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024; iron chelatin ABC transporter ATP-binding protein complement(1555042..1555803) Haemophilus influenzae Rd KW20 950600 NP_439622.1 CDS HI1471 NC_000907.1 1555796 1556809 R similar to GB:AE000511 SP:O05731 PID:2072455 PID:2314025; iron chelatin ABC transporter permease complement(1555796..1556809) Haemophilus influenzae Rd KW20 950354 NP_439623.1 CDS HI1472 NC_000907.1 1556796 1557851 R similar to GB:AE000511 PID:2314746; iron chelatin ABC transporter substrate-binding protein complement(1556796..1557851) Haemophilus influenzae Rd KW20 950575 NP_439624.1 CDS modD NC_000907.1 1557919 1558764 R involved in molybdenum transport; molybdenum transport protein ModD complement(1557919..1558764) Haemophilus influenzae Rd KW20 950721 NP_439625.1 CDS HI1474 NC_000907.1 1558774 1559373 R similar to GB:AE000511 PID:2313950; ABC transporter ATP-binding protein complement(1558774..1559373) Haemophilus influenzae Rd KW20 950574 NP_439626.1 CDS HI1475 NC_000907.1 1559375 1559734 R hypothetical protein complement(1559375..1559734) Haemophilus influenzae Rd KW20 950353 NP_439627.1 CDS HI1476 NC_000907.1 1559962 1560681 R similar to SP:Q37906 PID:403436; transcriptional regulatory protein complement(1559962..1560681) Haemophilus influenzae Rd KW20 950582 NP_439628.1 CDS ner NC_000907.1 1560909 1561178 D similar to SP:P06903; DNA-binding protein 1560909..1561178 Haemophilus influenzae Rd KW20 950789 NP_439629.1 CDS muA NC_000907.1 1561212 1563275 D similar to SP:P07636 PID:15450 PID:15810 PID:215511 PID:215547; transposase 1561212..1563275 Haemophilus influenzae Rd KW20 950583 NP_439630.1 CDS HI1479 NC_000907.1 1563332 1563604 D hypothetical protein 1563332..1563604 Haemophilus influenzae Rd KW20 950355 NP_439631.1 CDS HI1480 NC_000907.1 1563537 1564007 R hypothetical protein complement(1563537..1564007) Haemophilus influenzae Rd KW20 950577 NP_439632.1 CDS muB NC_000907.1 1564041 1564904 D similar to SP:P03763 PID:15448 PID:215512 PID:215550; DNA transposition protein 1564041..1564904 Haemophilus influenzae Rd KW20 950585 NP_439633.1 CDS HI1482 NC_000907.1 1564965 1565282 D hypothetical protein 1564965..1565282 Haemophilus influenzae Rd KW20 950568 NP_439634.1 CDS gam NC_000907.1 1565297 1565806 D similar to SP:P06023 PID:15461 PID:215562; host-nuclease inhibitor protein 1565297..1565806 Haemophilus influenzae Rd KW20 950566 NP_439635.1 CDS HI1485 NC_000907.1 1566436 1566657 D hypothetical protein 1566436..1566657 Haemophilus influenzae Rd KW20 950356 NP_439636.1 CDS HI1486 NC_000907.1 1566657 1566830 D hypothetical protein 1566657..1566830 Haemophilus influenzae Rd KW20 950578 NP_439637.1 CDS HI1487 NC_000907.1 1566833 1567393 D hypothetical protein 1566833..1567393 Haemophilus influenzae Rd KW20 950580 NP_439638.1 CDS HI1488 NC_000907.1 1567567 1568124 D similar to PID:215574; hypothetical protein 1567567..1568124 Haemophilus influenzae Rd KW20 950788 NP_439639.1 CDS HI1489 NC_000907.1 1568121 1568675 D hypothetical protein 1568121..1568675 Haemophilus influenzae Rd KW20 950579 NP_439641.1 CDS HI1492 NC_000907.1 1569309 1569815 D hypothetical protein 1569309..1569815 Haemophilus influenzae Rd KW20 950359 NP_439642.1 CDS HI1493 NC_000907.1 1569897 1570181 D hypothetical protein 1569897..1570181 Haemophilus influenzae Rd KW20 950360 NP_439644.1 CDS HI1495 NC_000907.1 1570448 1570708 D hypothetical protein 1570448..1570708 Haemophilus influenzae Rd KW20 950744 NP_439645.1 CDS HI1496 NC_000907.1 1570705 1570959 D hypothetical protein 1570705..1570959 Haemophilus influenzae Rd KW20 950362 NP_439646.1 CDS HI1497 NC_000907.1 1571077 1571304 D similar to SP:Q06424 PID:288658; hypothetical protein 1571077..1571304 Haemophilus influenzae Rd KW20 950363 NP_439647.1 CDS HI1498 NC_000907.1 1571211 1571630 D hypothetical protein 1571211..1571630 Haemophilus influenzae Rd KW20 950364 NP_439648.1 CDS HI1498.1 NC_000907.1 1571635 1571943 D hypothetical protein 1571635..1571943 Haemophilus influenzae Rd KW20 950365 NP_439649.1 CDS HI1499 NC_000907.1 1571955 1572524 D hypothetical protein 1571955..1572524 Haemophilus influenzae Rd KW20 950366 NP_439650.1 CDS HI1500 NC_000907.1 1572524 1574050 D hypothetical protein 1572524..1574050 Haemophilus influenzae Rd KW20 950367 NP_439651.1 CDS HI1501 NC_000907.1 1574062 1575624 D hypothetical protein 1574062..1575624 Haemophilus influenzae Rd KW20 950368 NP_439652.1 CDS HI1502 NC_000907.1 1575715 1576959 D hypothetical protein 1575715..1576959 Haemophilus influenzae Rd KW20 950369 NP_439653.1 CDS HI1503 NC_000907.1 1577097 1577537 D similar to bacteriophage Mu G-1 protein; SP:Q01261 PID:215535; Mu-like prophage FluMu G protein 1577097..1577537 Haemophilus influenzae Rd KW20 950371 NP_439654.1 CDS HI1504 NC_000907.1 1577768 1578835 D similar to bacteriophage Mu I protein; similar to SP:Q01267 PID:215536; bacteriophage Mu I protein 1577768..1578835 Haemophilus influenzae Rd KW20 950372 NP_439655.1 CDS HI1505 NC_000907.1 1578835 1579761 D hypothetical protein 1578835..1579761 Haemophilus influenzae Rd KW20 950373 NP_439658.1 CDS HI1508 NC_000907.1 1580232 1580657 D similar to PID:2353778; hypothetical protein 1580232..1580657 Haemophilus influenzae Rd KW20 950376 NP_439659.2 CDS HI1509 NC_000907.1 1580657 1581208 D similar to PID:2353777; hypothetical protein 1580657..1581208 Haemophilus influenzae Rd KW20 950377 NP_439660.1 CDS HI1510 NC_000907.1 1581221 1581412 D similar to PID:1834290; hypothetical protein 1581221..1581412 Haemophilus influenzae Rd KW20 950834 NP_439661.1 CDS HI1511 NC_000907.1 1581412 1582875 D similar to bacteriophage Mu L protein; PID:1834291; sheath protein gpL 1581412..1582875 Haemophilus influenzae Rd KW20 950573 NP_439662.1 CDS HI1512 NC_000907.1 1582885 1583241 D similar to PID:1834292; hypothetical protein 1582885..1583241 Haemophilus influenzae Rd KW20 950378 NP_439663.1 CDS HI1513 NC_000907.1 1583254 1583637 D similar to PID:1834293; hypothetical protein 1583254..1583637 Haemophilus influenzae Rd KW20 950379 NP_439664.1 CDS HI1514 NC_000907.1 1583718 1585613 D monofunctional biosynthetic peptidoglycan transglycosylase 1583718..1585613 Haemophilus influenzae Rd KW20 950380 NP_439665.1 CDS muN NC_000907.1 1585613 1586980 D similar to SP:P08557 PID:15105; 64 kDa virion protein 1585613..1586980 Haemophilus influenzae Rd KW20 950381 NP_439667.1 CDS HI1518 NC_000907.1 1588277 1588825 D hypothetical protein 1588277..1588825 Haemophilus influenzae Rd KW20 950383 NP_439668.1 CDS HI1519 NC_000907.1 1588834 1589241 D hypothetical protein 1588834..1589241 Haemophilus influenzae Rd KW20 950384 NP_439669.1 CDS HI1520 NC_000907.1 1589241 1590308 D similar to GB:U00096 PID:1787398; hypothetical protein 1589241..1590308 Haemophilus influenzae Rd KW20 950385 NP_439670.2 CDS HI1521 NC_000907.1 1590340 1590900 D similar to GB:U00096 PID:1787399; hypothetical protein 1590340..1590900 Haemophilus influenzae Rd KW20 950386 NP_439671.1 CDS HI1522 NC_000907.1 1590900 1592771 D hypothetical protein 1590900..1592771 Haemophilus influenzae Rd KW20 950387 NP_439672.1 CDS HI1522.1 NC_000907.1 1593255 1593374 D hypothetical protein 1593255..1593374 Haemophilus influenzae Rd KW20 950388 NP_439673.1 CDS HI1523 NC_000907.1 1593385 1594275 D hypothetical protein 1593385..1594275 Haemophilus influenzae Rd KW20 949672 NP_439674.1 CDS HI1525 NC_000907.1 1594829 1595566 R similar to GB:AE000666; molybdate-binding periplasmic protein complement(1594829..1595566) Haemophilus influenzae Rd KW20 950823 NP_439675.1 CDS rfaE NC_000907.1 1595753 1597183 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(1595753..1597183) Haemophilus influenzae Rd KW20 949890 NP_439676.2 CDS htrB NC_000907.1 1597280 1598215 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1597280..1598215 Haemophilus influenzae Rd KW20 950389 NP_439677.1 CDS parE NC_000907.1 1598289 1600187 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1598289..1600187 Haemophilus influenzae Rd KW20 950390 NP_439678.1 CDS parC NC_000907.1 1600254 1602497 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1600254..1602497 Haemophilus influenzae Rd KW20 950391 NP_439679.1 CDS gltS NC_000907.1 1602539 1603753 D similar to GB:L10328 SP:P19933 GB:D00626 GB:X17499 PID:216541; glutamate permease 1602539..1603753 Haemophilus influenzae Rd KW20 950392 NP_439680.1 CDS rimK NC_000907.1 1603792 1604700 R similar to SP:P17116 GB:X15859 PID:42747 GB:U00096 PID:1651386; ribosomal protein S6 modification protein complement(1603792..1604700) Haemophilus influenzae Rd KW20 950393 NP_439681.1 CDS grxA NC_000907.1 1604817 1605080 D functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1604817..1605080 Haemophilus influenzae Rd KW20 950394 NP_439682.1 CDS fabB NC_000907.1 1605147 1606367 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(1605147..1606367) Haemophilus influenzae Rd KW20 950395 NP_439686.1 CDS licA NC_000907.1 1608780 1609583 D similar to GB:M27280 SP:P14181 GB:M37912 PID:1574379; lic-1 operon protein 1608780..1609583 Haemophilus influenzae Rd KW20 950399 NP_439687.1 CDS licB NC_000907.1 1609583 1610461 D similar to GB:M27280 SP:P14182; lic-1 operon protein 1609583..1610461 Haemophilus influenzae Rd KW20 950400 NP_439688.1 CDS licC NC_000907.1 1610458 1611159 D similar to GB:M27280 SP:P14183; lic-1 operon protein 1610458..1611159 Haemophilus influenzae Rd KW20 950402 NP_439689.1 CDS licD NC_000907.1 1611159 1611956 D similar to GB:M27280 SP:P14184; lic-1 operon protein 1611159..1611956 Haemophilus influenzae Rd KW20 950403 NP_439690.1 CDS sppA NC_000907.1 1611994 1613841 R similar to GB:M13359 SP:P08395 GB:U13772 GB:U13773 GB:U13774; protease IV complement(1611994..1613841) Haemophilus influenzae Rd KW20 950404 NP_439691.1 CDS HI1542 NC_000907.1 1613939 1614493 D similar to PID:2253239; hypothetical protein 1613939..1614493 Haemophilus influenzae Rd KW20 950405 NP_439692.1 CDS HI1543 NC_000907.1 1614541 1615095 R similar to GB:U00096 SP:P75915 PID:1787272; anaerobic dehydrogenase subunit complement(1614541..1615095) Haemophilus influenzae Rd KW20 950406 NP_439693.1 CDS HI1544 NC_000907.1 1615095 1615703 R similar to SP:Q64669 PID:595518; NAD(P)H oxidoreductase complement(1615095..1615703) Haemophilus influenzae Rd KW20 950407 NP_439694.1 CDS HI1545 NC_000907.1 1615824 1617068 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(1615824..1617068) Haemophilus influenzae Rd KW20 950408 NP_439695.1 CDS HI1546 NC_000907.1 1617353 1617775 D hypothetical protein 1617353..1617775 Haemophilus influenzae Rd KW20 950409 NP_439696.1 CDS aroG NC_000907.1 1617864 1618952 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1617864..1618952) Haemophilus influenzae Rd KW20 950411 NP_439697.1 CDS HI1548 NC_000907.1 1619170 1620420 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE complement(1619170..1620420) Haemophilus influenzae Rd KW20 950412 NP_439698.1 CDS HI1549 NC_000907.1 1620420 1621103 R similar to GB:U00096 SP:P75957 PID:1787361; ABC transporter ATP-binding protein complement(1620420..1621103) Haemophilus influenzae Rd KW20 950413 NP_439699.1 CDS bioD NC_000907.1 1621250 1621825 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1621250..1621825) Haemophilus influenzae Rd KW20 950414 NP_439700.1 CDS HI1551 NC_000907.1 1621835 1622617 R similar to GB:J04423 SP:P12999 PID:145427 PID:490221 GB:U00096; biotin synthase complement(1621835..1622617) Haemophilus influenzae Rd KW20 950415 NP_439701.1 CDS HI1552 NC_000907.1 1622605 1623252 R hypothetical protein complement(1622605..1623252) Haemophilus influenzae Rd KW20 950563 NP_439702.1 CDS bioF NC_000907.1 1623262 1624404 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(1623262..1624404) Haemophilus influenzae Rd KW20 950334 NP_439703.1 CDS bioA NC_000907.1 1624413 1625705 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(1624413..1625705) Haemophilus influenzae Rd KW20 950608 NP_439704.1 CDS HI1555 NC_000907.1 1625724 1626905 R similar to GB:U00096 SP:P75956 PID:1787360; hypothetical protein complement(1625724..1626905) Haemophilus influenzae Rd KW20 949639 NP_439705.1 CDS HI1556 NC_000907.1 1626905 1627852 R Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase complement(1626905..1627852) Haemophilus influenzae Rd KW20 950416 NP_439706.1 CDS kdsA NC_000907.1 1627912 1628766 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1627912..1628766) Haemophilus influenzae Rd KW20 950417 NP_439707.1 CDS HI1558 NC_000907.1 1628781 1629584 R similar to SP:P20101 GB:X05552 PID:41872 PID:1008040 GB:U00096; hypothetical protein complement(1628781..1629584) Haemophilus influenzae Rd KW20 950418 NP_439708.1 CDS hemK NC_000907.1 1629584 1630462 R similar to GB:D28567 SP:P37186 PID:466533 PID:968931 GB:U00096; hypothetical protein complement(1629584..1630462) Haemophilus influenzae Rd KW20 950419 NP_439709.1 CDS HI1560 NC_000907.1 1630462 1630932 R hypothetical protein complement(1630462..1630932) Haemophilus influenzae Rd KW20 950420 NP_439710.1 CDS prfA NC_000907.1 1630955 1632040 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1630955..1632040) Haemophilus influenzae Rd KW20 950421 NP_439712.1 CDS HI1563 NC_000907.1 1632558 1633094 R similar to GB:U00096 PID:1788666; hypothetical protein complement(1632558..1633094) Haemophilus influenzae Rd KW20 950423 NP_439713.1 CDS HI1564 NC_000907.1 1633127 1633279 R hypothetical protein complement(1633127..1633279) Haemophilus influenzae Rd KW20 950424 NP_439715.1 CDS HI1568 NC_000907.1 1636791 1637207 R similar to bacteriophage Mu G-2 protein; SP:Q01261 PID:215535; Mu-like prophage FluMu G protein complement(1636791..1637207) Haemophilus influenzae Rd KW20 950426 NP_439717.1 CDS HI1571 NC_000907.1 1638049 1638288 R hypothetical protein complement(1638049..1638288) Haemophilus influenzae Rd KW20 950428 NP_439719.1 CDS pykA NC_000907.1 1640232 1641668 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1640232..1641668 Haemophilus influenzae Rd KW20 950433 NP_439720.1 CDS dnaB NC_000907.1 1641702 1643216 D unwinds double stranded DNA; replicative DNA helicase 1641702..1643216 Haemophilus influenzae Rd KW20 950434 NP_439721.1 CDS alr NC_000907.1 1643226 1644308 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1643226..1644308 Haemophilus influenzae Rd KW20 950435 NP_439722.2 CDS pgi NC_000907.1 1644405 1646054 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1644405..1646054 Haemophilus influenzae Rd KW20 950436 NP_439724.1 CDS HI1578 NC_000907.1 1646702 1647673 D similar to PID:595813; glycosyl transferase 1646702..1647673 Haemophilus influenzae Rd KW20 950438 NP_439725.1 CDS lpp NC_000907.1 1647856 1648323 R similar to GB:M18877 SP:P10325; 15 kDa peptidoglycan-associated lipoprotein complement(1647856..1648323) Haemophilus influenzae Rd KW20 950439 NP_439728.1 CDS argS NC_000907.1 1649297 1651030 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1649297..1651030 Haemophilus influenzae Rd KW20 950446 NP_439729.1 CDS ilvH NC_000907.1 1651323 1651814 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(1651323..1651814) Haemophilus influenzae Rd KW20 950447 NP_439730.1 CDS ilvI NC_000907.1 1651814 1653535 R acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 3 catalytic subunit complement(1651814..1653535) Haemophilus influenzae Rd KW20 950449 NP_439731.1 CDS HI1586 NC_000907.1 1653802 1655361 R similar to GB:AE000511 PID:2314087; isoleucyl-tRNA synthetase complement(1653802..1655361) Haemophilus influenzae Rd KW20 950450 NP_439732.1 CDS hns NC_000907.1 1655765 1656169 D similar to GB:X07688 SP:P08936 GB:X57231 GB:X59940 GB:X67326; DNA-binding protein H-NS 1655765..1656169 Haemophilus influenzae Rd KW20 950451 NP_439733.1 CDS purU NC_000907.1 1656239 1657075 D produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1656239..1657075 Haemophilus influenzae Rd KW20 950306 NP_439734.1 CDS aroA NC_000907.1 1657075 1658373 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1657075..1658373 Haemophilus influenzae Rd KW20 950448 NP_439735.1 CDS HI1590 NC_000907.1 1658455 1659795 R similar to SP:P45526 GB:U00096 PID:1787119; recombination factor protein RarA complement(1658455..1659795) Haemophilus influenzae Rd KW20 950837 NP_439736.1 CDS lolA NC_000907.1 1659856 1660473 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(1659856..1660473) Haemophilus influenzae Rd KW20 950452 NP_439738.2 CDS lrp NC_000907.1 1663262 1663741 R mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator complement(1663262..1663741) Haemophilus influenzae Rd KW20 950361 NP_439739.2 CDS radA NC_000907.1 1663821 1665197 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(1663821..1665197) Haemophilus influenzae Rd KW20 950453 NP_439740.1 CDS HI1598 NC_000907.1 1665333 1666391 R similar to SP:P30871 GB:Z21844 PID:49399 GB:U00096 PID:1789434; hypothetical protein complement(1665333..1666391) Haemophilus influenzae Rd KW20 950454 NP_439741.2 CDS HI1599 NC_000907.1 1666703 1667401 R hypothetical protein complement(1666703..1667401) Haemophilus influenzae Rd KW20 950442 NP_439742.1 CDS HI1600 NC_000907.1 1667409 1668362 R hypothetical protein complement(1667409..1668362) Haemophilus influenzae Rd KW20 950455 NP_439743.1 CDS HI1601 NC_000907.1 1668392 1668679 R hypothetical protein complement(1668392..1668679) Haemophilus influenzae Rd KW20 950456 NP_439744.2 CDS HI1602 NC_000907.1 1668718 1669158 R hypothetical protein complement(1668718..1669158) Haemophilus influenzae Rd KW20 950457 NP_439745.1 CDS HI1603 NC_000907.1 1669381 1670061 D similar to GB:AE000782; phosphate transport regulator 1669381..1670061 Haemophilus influenzae Rd KW20 950838 NP_439746.1 CDS HI1604 NC_000907.1 1670086 1671348 D similar to PID:1814405; phosphate permease 1670086..1671348 Haemophilus influenzae Rd KW20 950410 NP_439747.1 CDS HI1605 NC_000907.1 1671414 1672025 D similar to SP:P39202 PID:1203798 GB:U00096 PID:1789435; hypothetical protein 1671414..1672025 Haemophilus influenzae Rd KW20 950458 NP_439748.1 CDS cca NC_000907.1 1672032 1673282 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1672032..1673282 Haemophilus influenzae Rd KW20 950839 NP_439749.1 CDS lolB NC_000907.1 1673345 1673974 D Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1673345..1673974 Haemophilus influenzae Rd KW20 950296 NP_439750.1 CDS ipk NC_000907.1 1673986 1674927 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1673986..1674927 Haemophilus influenzae Rd KW20 950459 NP_439751.1 CDS prsA NC_000907.1 1674929 1675876 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1674929..1675876 Haemophilus influenzae Rd KW20 950463 NP_439752.1 CDS tyrS NC_000907.1 1675940 1677145 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1675940..1677145) Haemophilus influenzae Rd KW20 950464 NP_439753.1 CDS sfsA NC_000907.1 1677346 1678062 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(1677346..1678062) Haemophilus influenzae Rd KW20 950840 NP_439754.1 CDS HI1612 NC_000907.1 1678071 1679465 R NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein complement(1678071..1679465) Haemophilus influenzae Rd KW20 950466 NP_439755.1 CDS ribE NC_000907.1 1679509 1680123 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1679509..1680123 Haemophilus influenzae Rd KW20 950465 NP_439756.1 CDS pepN NC_000907.1 1680195 1682804 R similar to GB:M15273 SP:P04825 GB:M15676 GB:X04020 PID:147142; aminopeptidase N complement(1680195..1682804) Haemophilus influenzae Rd KW20 950613 NP_439757.1 CDS purE NC_000907.1 1682965 1683459 D Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 1682965..1683459 Haemophilus influenzae Rd KW20 949616 NP_439758.1 CDS purK NC_000907.1 1683529 1684617 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1683529..1684617 Haemophilus influenzae Rd KW20 950468 NP_439759.1 CDS aspC NC_000907.1 1684756 1685946 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1684756..1685946 Haemophilus influenzae Rd KW20 950841 NP_439760.2 CDS HI1618 NC_000907.1 1686173 1686790 R similar to GB:AE000666; ABC transporter ATP-binding protein complement(1686173..1686790) Haemophilus influenzae Rd KW20 950842 NP_439763.1 CDS HI1621 NC_000907.1 1687425 1688045 R catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM complement(1687425..1688045) Haemophilus influenzae Rd KW20 950848 NP_439764.1 CDS HI1622 NC_000907.1 1688045 1688530 R hypothetical protein complement(1688045..1688530) Haemophilus influenzae Rd KW20 950474 NP_439765.1 CDS HI1624 NC_000907.1 1688543 1689226 R branched chain amino acid ABC transporter substrate-binding protein complement(1688543..1689226) Haemophilus influenzae Rd KW20 950470 NP_439766.1 CDS merR2 NC_000907.1 1689316 1689723 D similar to GB:X57326 PID:48151; mercuric resistance operon regulatory protein 1689316..1689723 Haemophilus influenzae Rd KW20 950843 NP_439767.1 CDS HI1625 NC_000907.1 1689783 1690280 R hypothetical protein complement(1689783..1690280) Haemophilus influenzae Rd KW20 950478 NP_439768.1 CDS HI1626 NC_000907.1 1690281 1690997 R similar to SP:P46909 PID:971339 GB:AL009126; hypothetical protein complement(1690281..1690997) Haemophilus influenzae Rd KW20 950846 NP_439769.1 CDS HI1627 NC_000907.1 1691109 1691459 D similar to PID:2407234; hypothetical protein 1691109..1691459 Haemophilus influenzae Rd KW20 950462 NP_439770.1 CDS HI1628 NC_000907.1 1691490 1691894 D similar to SP:P39436 PID:606172 GB:U00096 PID:1789628; hypothetical protein 1691490..1691894 Haemophilus influenzae Rd KW20 950472 NP_439771.2 CDS HI1629 NC_000907.1 1691957 1692544 R similar to GB:M68934 SP:P09548 GB:X02743 PID:146363 GB:U00096; hypothetical protein complement(1691957..1692544) Haemophilus influenzae Rd KW20 950844 NP_439772.1 CDS rpL25 NC_000907.1 1692762 1693049 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1692762..1693049 Haemophilus influenzae Rd KW20 950473 NP_439773.1 CDS HI1631 NC_000907.1 1693148 1693720 R hypothetical protein complement(1693148..1693720) Haemophilus influenzae Rd KW20 950845 NP_439774.1 CDS HI1632 NC_000907.1 1694577 1694942 D hypothetical protein 1694577..1694942 Haemophilus influenzae Rd KW20 950850 NP_439775.1 CDS purA NC_000907.1 1695071 1696369 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1695071..1696369 Haemophilus influenzae Rd KW20 950476 NP_439776.2 CDS dapD NC_000907.1 1696426 1697253 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(1696426..1697253) Haemophilus influenzae Rd KW20 950847 NP_439777.1 CDS purR NC_000907.1 1697612 1698622 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1697612..1698622 Haemophilus influenzae Rd KW20 950319 NP_439778.1 CDS ppc NC_000907.1 1698805 1701444 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1698805..1701444 Haemophilus influenzae Rd KW20 950481 NP_439779.1 CDS HI1637 NC_000907.1 1701481 1702893 R similar to GB:U00096 PID:1787581; hypothetical protein complement(1701481..1702893) Haemophilus influenzae Rd KW20 950851 NP_439780.1 CDS sapA NC_000907.1 1702963 1704660 D similar to SP:P36634 GB:X52093 GB:X74212 PID:414208; anti peptide resistance ABC transporter substrate-binding protein 1702963..1704660 Haemophilus influenzae Rd KW20 950479 NP_439781.1 CDS sapB NC_000907.1 1704660 1705625 D similar to SP:P36668 GB:X52093 GB:X74212 PID:414209; peptide ABC transporter permease 1704660..1705625 Haemophilus influenzae Rd KW20 950849 NP_439782.1 CDS sapC NC_000907.1 1705615 1706502 D similar to SP:P36669 GB:X74212 PID:414210; peptide ABC transporter permease 1705615..1706502 Haemophilus influenzae Rd KW20 950835 NP_439783.1 CDS sapD NC_000907.1 1706506 1707555 D similar to SP:P36636 GB:X74212 PID:414211; peptide ABC transporter ATP-binding protein 1706506..1707555 Haemophilus influenzae Rd KW20 950483 NP_439784.1 CDS sapF NC_000907.1 1707555 1708364 D similar to SP:P36637 GB:U08190 PID:470683 GB:U00096 PID:1279404; anti peptide resistance ABC transporter ATPase 1707555..1708364 Haemophilus influenzae Rd KW20 950853 NP_439785.1 CDS HI1643 NC_000907.1 1708376 1709392 D similar to SP:P33019 PID:405879 GB:U00096 PID:1788482; hypothetical protein 1708376..1709392 Haemophilus influenzae Rd KW20 950484 NP_439786.1 CDS truA NC_000907.1 1709484 1710293 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1709484..1710293) Haemophilus influenzae Rd KW20 950487 NP_439787.1 CDS fbp NC_000907.1 1710527 1711528 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1710527..1711528 Haemophilus influenzae Rd KW20 950852 NP_439788.1 CDS cmk NC_000907.1 1711447 1712115 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1711447..1712115) Haemophilus influenzae Rd KW20 950485 NP_439789.1 CDS HI1647 NC_000907.1 1712590 1713465 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1712590..1713465 Haemophilus influenzae Rd KW20 950488 NP_439790.2 CDS HI1648 NC_000907.1 1713466 1714044 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1713466..1714044 Haemophilus influenzae Rd KW20 950854 NP_439791.1 CDS dld NC_000907.1 1714592 1716286 R component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase complement(1714592..1716286) Haemophilus influenzae Rd KW20 950490 NP_439792.1 CDS HI1650 NC_000907.1 1716547 1716657 D hypothetical protein 1716547..1716657 Haemophilus influenzae Rd KW20 950489 NP_439793.1 CDS HI1651 NC_000907.1 1716772 1717050 R nucleotide sequence similar to HI0220; hypothetical protein complement(1716772..1717050) Haemophilus influenzae Rd KW20 950855 NP_439794.1 CDS spr NC_000907.1 1717801 1718352 R similar to GB:U00096 SP:P77685 PID:1498150 PID:1736840 PID:1788501; lipoprotein complement(1717801..1718352) Haemophilus influenzae Rd KW20 950494 NP_439795.2 CDS tldD NC_000907.1 1718465 1719912 R similar to Zn-dependent protease; this region contains an authentic frame shift and is not the result of a sequencing artifact; similar to SP:P46473 PID:606183 GB:U00096 PID:1732437 PID:1789640; hypothetical protein complement(join(1718465..1718884,1718884..1719912)) Haemophilus influenzae Rd KW20 950857 NP_439796.1 CDS HI1654 NC_000907.1 1720014 1720865 R similar to SP:P45528 PID:606086 GB:U00096 PID:1789535; hypothetical protein complement(1720014..1720865) Haemophilus influenzae Rd KW20 950491 NP_439797.1 CDS HI1655 NC_000907.1 1720937 1722664 D similar to PID:1353671; antigen 1720937..1722664 Haemophilus influenzae Rd KW20 950219 NP_439798.1 CDS HI1656 NC_000907.1 1722664 1723023 D similar to SP:P45465 PID:606088 GB:U00096 PID:1789538; hypothetical protein 1722664..1723023 Haemophilus influenzae Rd KW20 950807 NP_439799.1 CDS HI1657 NC_000907.1 1723036 1723620 D similar to SP:P45466 PID:606089 GB:U00096 PID:1789539; hypothetical protein 1723036..1723620 Haemophilus influenzae Rd KW20 950796 NP_439800.1 CDS HI1658 NC_000907.1 1723677 1724258 D similar to SP:P45467 PID:606090 GB:U00096 PID:1789540; hypothetical protein 1723677..1724258 Haemophilus influenzae Rd KW20 950803 NP_439801.2 CDS nrdA NC_000907.1 1724513 1726783 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1724513..1726783 Haemophilus influenzae Rd KW20 950495 NP_439802.1 CDS nrdB NC_000907.1 1726925 1728055 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1726925..1728055 Haemophilus influenzae Rd KW20 950858 NP_439803.1 CDS sucB NC_000907.1 1728171 1729400 R similar to GB:J01619 SP:P07016 GB:X00664 PID:146202 PID:43022; 2-oxoglutarate dehydrogenase E2 component dihydrolipoamide succinyltransferase complement(1728171..1729400) Haemophilus influenzae Rd KW20 950492 NP_439804.2 CDS sucA NC_000907.1 1729503 1732310 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(1729503..1732310) Haemophilus influenzae Rd KW20 950496 NP_439805.1 CDS HI1663 NC_000907.1 1732513 1733151 R similar to GB:U00096 SP:P75849 PID:1787158; hypothetical protein complement(1732513..1733151) Haemophilus influenzae Rd KW20 950497 NP_439806.2 CDS HI1664 NC_000907.1 1733161 1733916 R similar to GB:U00089 SP:P78005 PID:1673805; hypothetical protein complement(1733161..1733916) Haemophilus influenzae Rd KW20 950504 NP_439809.1 CDS HI1667 NC_000907.1 1734543 1736012 R similar to SP:P22525 GB:X57550 PID:42044 GB:U00096 PID:1787155; hypothetical protein complement(1734543..1736012) Haemophilus influenzae Rd KW20 950498 NP_439810.1 CDS prc NC_000907.1 1736086 1738173 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1736086..1738173) Haemophilus influenzae Rd KW20 950859 NP_439812.1 CDS HI1670 NC_000907.1 1738359 1738832 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(1738359..1738832) Haemophilus influenzae Rd KW20 950501 NP_439813.1 CDS HI1671 NC_000907.1 1739016 1740266 D similar to GB:U00096 PID:1736474 PID:1736480 PID:1788137; hypothetical protein 1739016..1740266 Haemophilus influenzae Rd KW20 950860 NP_439814.1 CDS HI1672 NC_000907.1 1740250 1742895 D similar to GB:U00096 PID:1736475 PID:1736481 PID:1788138; hypothetical protein 1740250..1742895 Haemophilus influenzae Rd KW20 950502 NP_439815.1 CDS moaE NC_000907.1 1742950 1743402 R similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003; molybdopterin converting factor subunit 2 complement(1742950..1743402) Haemophilus influenzae Rd KW20 950861 NP_439816.1 CDS moaD NC_000907.1 1743403 1743648 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit complement(1743403..1743648) Haemophilus influenzae Rd KW20 950503 NP_439817.1 CDS moaC NC_000907.1 1743650 1744132 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(1743650..1744132) Haemophilus influenzae Rd KW20 950864 NP_439818.1 CDS moaA NC_000907.1 1744224 1745237 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(1744224..1745237) Haemophilus influenzae Rd KW20 950505 NP_439819.1 CDS HI1677 NC_000907.1 1745682 1746353 D Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 1745682..1746353 Haemophilus influenzae Rd KW20 950862 NP_439820.1 CDS kpsF NC_000907.1 1746890 1747903 D similar to GB:L19929 SP:P42502 PID:455424; arabinose-5-phosphate isomerase KpsF 1746890..1747903 Haemophilus influenzae Rd KW20 950863 NP_439821.1 CDS yrbI NC_000907.1 1747913 1748455 D forms homotetramers; similar to SP:P45396 PID:606137 GB:U00096 PID:2367202; phosphatase 1747913..1748455 Haemophilus influenzae Rd KW20 950506 NP_439822.1 CDS HI1680 NC_000907.1 1748553 1750709 R similar to GB:U00096 PID:1787194; hypothetical protein complement(1748553..1750709) Haemophilus influenzae Rd KW20 950508 NP_439823.1 CDS HI1681 NC_000907.1 1750777 1751442 R similar to GB:U00096 PID:1787198; hypothetical protein complement(1750777..1751442) Haemophilus influenzae Rd KW20 950865 NP_439824.1 CDS sohB NC_000907.1 1751640 1752701 D SohB; periplasmic protein; member of the peptidase S49 family; protease 1751640..1752701 Haemophilus influenzae Rd KW20 950509 NP_439825.1 CDS HI1683 NC_000907.1 1752983 1753561 D similar to rnfA/rnfE proteins; similar to GB:U00096 PID:1787914; Na(+)-translocating NADH-quinone reductase subunit E 1752983..1753561 Haemophilus influenzae Rd KW20 950867 NP_439826.1 CDS HI1684 NC_000907.1 1753649 1754230 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1753649..1754230 Haemophilus influenzae Rd KW20 950511 NP_439827.1 CDS HI1685 NC_000907.1 1754231 1756690 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1754231..1756690 Haemophilus influenzae Rd KW20 950866 NP_439828.1 CDS rnfD NC_000907.1 1756695 1757771 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1756695..1757771 Haemophilus influenzae Rd KW20 950513 NP_439829.1 CDS rnfG NC_000907.1 1757771 1758394 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1757771..1758394 Haemophilus influenzae Rd KW20 950514 NP_439830.1 CDS HI1688 NC_000907.1 1758396 1759103 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1758396..1759103 Haemophilus influenzae Rd KW20 950516 NP_439831.1 CDS nth NC_000907.1 1759288 1759923 D similar to GB:J02857 SP:P20625 PID:146972 GB:U00096 PID:1742691; endonuclease III 1759288..1759923 Haemophilus influenzae Rd KW20 950507 NP_439832.1 CDS HI1690 NC_000907.1 1759981 1761354 D similar to GB:AL009126; sodium-dependent transporter 1759981..1761354 Haemophilus influenzae Rd KW20 950500 NP_439833.1 CDS modC NC_000907.1 1761378 1762433 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(1761378..1762433) Haemophilus influenzae Rd KW20 950518 NP_439834.1 CDS modB NC_000907.1 1762420 1763109 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease complement(1762420..1763109) Haemophilus influenzae Rd KW20 949953 NP_439835.1 CDS modA NC_000907.1 1763283 1764047 R similar to GB:L34009 SP:P37329 PID:504498 PID:973214 PID:1147817; molybdenum ABC transporter substrate-binding protein complement(1763283..1764047) Haemophilus influenzae Rd KW20 950605 NP_439836.1 CDS modE NC_000907.1 1764185 1764952 D similar to PID:1002825 SP:P46930 GB:U00096 PID:1147816 PID:1786976; molybdenum transport protein 1764185..1764952 Haemophilus influenzae Rd KW20 950754 NP_439837.2 CDS HI1695 NC_000907.1 1765061 1765846 R similar to PID:600434 SP:Q46635; UDP-galactose--lipooligosaccharide galactosyltransferase complement(1765061..1765846) Haemophilus influenzae Rd KW20 950753 NP_439838.1 CDS HI1696 NC_000907.1 1765866 1766750 R similar to PID:1944156; lipopolysaccharide biosynthesis protein complement(1765866..1766750) Haemophilus influenzae Rd KW20 950519 NP_439839.1 CDS HI1697 NC_000907.1 1766762 1767535 R similar to GB:U05670; UDP-GlcNAc--lipooligosaccharide N-acetylglucosaminyl glycosyltransferase complement(1766762..1767535) Haemophilus influenzae Rd KW20 950869 NP_439840.1 CDS HI1698 NC_000907.1 1767547 1768608 R similar to PID:633695; lipopolysaccharide biosynthesis protein complement(1767547..1768608) Haemophilus influenzae Rd KW20 950521 NP_439841.1 CDS HI1699 NC_000907.1 1768610 1769524 R similar to PID:1546004; lipopolysaccharide biosynthesis protein complement(1768610..1769524) Haemophilus influenzae Rd KW20 950520 NP_439842.2 CDS HI1700 NC_000907.1 1769521 1770726 R similar to GB:AE000666; lipopolysaccharide biosynthesis protein complement(1769521..1770726) Haemophilus influenzae Rd KW20 950658 NP_439843.1 CDS HI1701 NC_000907.1 1770861 1771604 D similar to PID:1652989; hypothetical protein 1770861..1771604 Haemophilus influenzae Rd KW20 949784 NP_439844.1 CDS metE NC_000907.1 1771826 1774096 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase complement(1771826..1774096) Haemophilus influenzae Rd KW20 949942 NP_439845.1 CDS HI1703 NC_000907.1 1774289 1775365 R similar to GB:U14003 SP:P39341 PID:537104 GB:U00096 PID:1790713; hypothetical protein complement(1774289..1775365) Haemophilus influenzae Rd KW20 950522 NP_439846.1 CDS HI1704 NC_000907.1 1775349 1776467 R similar to GB:U14003 SP:P39340 PID:537103 GB:U00096 PID:1790712; hypothetical protein complement(1775349..1776467) Haemophilus influenzae Rd KW20 949709 NP_439847.1 CDS pepA NC_000907.1 1776575 1778050 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1776575..1778050 Haemophilus influenzae Rd KW20 949712 NP_439848.2 CDS betT NC_000907.1 1778086 1780029 R similar to SP:P17447 GB:X52905 PID:48716 GB:U00096 PID:1657512; high affinity choline transport protein complement(1778086..1780029) Haemophilus influenzae Rd KW20 950523 NP_439849.1 CDS ygiY NC_000907.1 1780390 1781745 R similar to SP:P40719 PID:882556 GB:U00096 PID:1789403; sensor protein QseC complement(1780390..1781745) Haemophilus influenzae Rd KW20 950868 NP_439850.1 CDS ygiX NC_000907.1 1781742 1782407 R similar to PID:882555 SP:P52076 GB:U00096 PID:1789402; transcriptional regulatory protein complement(1781742..1782407) Haemophilus influenzae Rd KW20 950525 NP_439851.1 CDS HI1709 NC_000907.1 1782470 1782835 R similar to PID:882554 SP:P52083 GB:U00096 PID:1789401; hypothetical protein complement(1782470..1782835) Haemophilus influenzae Rd KW20 950526 NP_439853.1 CDS crr NC_000907.1 1783345 1783845 R functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit complement(1783345..1783845) Haemophilus influenzae Rd KW20 950531 NP_439854.1 CDS ptsI NC_000907.1 1783905 1785632 R Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase complement(1783905..1785632) Haemophilus influenzae Rd KW20 950872 NP_439855.1 CDS ptsH NC_000907.1 1785712 1785969 R similar to SP:P07006 PID:153936 PID:47845; phosphocarrier protein HPr complement(1785712..1785969) Haemophilus influenzae Rd KW20 950527 NP_439856.1 CDS HI1714 NC_000907.1 1786128 1787168 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1786128..1787168) Haemophilus influenzae Rd KW20 950871 NP_439857.1 CDS HI1715 NC_000907.1 1787239 1787787 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1787239..1787787 Haemophilus influenzae Rd KW20 950529 NP_439858.1 CDS HI1716 NC_000907.1 1788088 1789155 R rfe; similar to GB:M87049 SP:P24235 GB:M76129 PID:147578 PID:148187; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase complement(1788088..1789155) Haemophilus influenzae Rd KW20 950539 NP_439860.1 CDS glnD NC_000907.1 1790426 1793017 R similar to GB:M96431 SP:P27249 PID:146155 PID:49393 PID:473822; PII uridylyl-transferase complement(1790426..1793017) Haemophilus influenzae Rd KW20 950533 NP_439861.2 CDS HI1720 NC_000907.1 1793136 1793645 D similar to GB:U09558 PID:495495; hypothetical protein 1793136..1793645 Haemophilus influenzae Rd KW20 950873 NP_439862.2 CDS HI1721 NC_000907.1 1793696 1794463 D similar to SP:P19769 GB:X07037 PID:581111 PID:912474 GB:U00096; transposase 1793696..1794463 Haemophilus influenzae Rd KW20 950534 NP_439863.1 CDS map NC_000907.1 1794526 1795332 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1794526..1795332) Haemophilus influenzae Rd KW20 950876 NP_439864.1 CDS HI1723 NC_000907.1 1795468 1795812 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1795468..1795812 Haemophilus influenzae Rd KW20 950536 NP_439865.2 CDS HI1724 NC_000907.1 1795814 1796167 D similar to SP:P45567 GB:U00096 PID:1786310; hypothetical protein 1795814..1796167 Haemophilus influenzae Rd KW20 950875 NP_439866.1 CDS ponB NC_000907.1 1796174 1798519 D similar to GB:D26562 SP:P02919 GB:M12486 GB:X02163 PID:145948; penicillin-binding protein 1B 1796174..1798519 Haemophilus influenzae Rd KW20 950545 NP_439867.2 CDS hemH NC_000907.1 1798692 1799564 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1798692..1799564 Haemophilus influenzae Rd KW20 950883 NP_439868.1 CDS argG NC_000907.1 1799720 1801054 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 1799720..1801054 Haemophilus influenzae Rd KW20 950537 NP_439869.1 CDS HI1728 NC_000907.1 1801125 1802318 R similar to SP:P42964 PID:707085 PID:1805475 GB:AL009126; hypothetical protein complement(1801125..1802318) Haemophilus influenzae Rd KW20 950517 NP_439870.1 CDS HI1729m NC_000907.1 1802362 1803099 R LamB/YcsF family protein complement(1802362..1803099) Haemophilus influenzae Rd KW20 950524 NP_439871.1 CDS HI1730 NC_000907.1 1803086 1804015 R similar to GB:U00096 SP:P75745 PID:1786930; hypothetical protein complement(1803086..1804015) Haemophilus influenzae Rd KW20 950540 NP_439872.1 CDS HI1731 NC_000907.1 1804012 1804653 R similar to GB:U00096 SP:P75744 PID:1786929; hypothetical protein complement(1804012..1804653) Haemophilus influenzae Rd KW20 950880 NP_439873.1 CDS HI1731a NC_000907.1 1804886 1807948 R Hsf-like protein complement(1804886..1807948) Haemophilus influenzae Rd KW20 950541 NP_439875.1 CDS rnb NC_000907.1 1809215 1811194 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1809215..1811194) Haemophilus influenzae Rd KW20 950879 NP_439876.2 CDS fabI NC_000907.1 1811277 1812065 R acyl-carrier-protein reductase; similar to GB:M97219 SP:P29132 GB:X78733 PID:145851 PID:587106; enoyl reductase complement(1811277..1812065) Haemophilus influenzae Rd KW20 950535 NP_439877.1 CDS prfC NC_000907.1 1812244 1813827 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1812244..1813827 Haemophilus influenzae Rd KW20 950874 NP_439878.1 CDS HI1736 NC_000907.1 1813903 1814136 R hypothetical protein complement(1813903..1814136) Haemophilus influenzae Rd KW20 950544 NP_439879.1 CDS HI1737 NC_000907.1 1814239 1814568 R similar to GB:AL009126; branched-chain amino acid ABC transporter permease complement(1814239..1814568) Haemophilus influenzae Rd KW20 950881 NP_439880.1 CDS HI1738 NC_000907.1 1814565 1815299 R similar to GB:AL009126; branched-chain amino acid ABC transporter permease complement(1814565..1815299) Haemophilus influenzae Rd KW20 950553 NP_439881.1 CDS metR NC_000907.1 1815309 1816238 R similar to GB:J04155 SP:P19797 GB:M37630 PID:1790262; transcriptional activator complement(1815309..1816238) Haemophilus influenzae Rd KW20 950886 NP_439882.1 CDS lldD NC_000907.1 1822366 1823511 R flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase complement(1822366..1823511) Haemophilus influenzae Rd KW20 950543 NP_439883.1 CDS murI NC_000907.1 1823723 1824532 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1823723..1824532) Haemophilus influenzae Rd KW20 950882 NP_439884.1 CDS recG NC_000907.1 1824562 1826643 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1824562..1826643) Haemophilus influenzae Rd KW20 950549 NP_439885.2 CDS spoT NC_000907.1 1826640 1828754 R similar to GB:L10328 SP:P17580 GB:M24503 PID:290500 PID:551840; guanosine-3'5'-bis(diphosphate) 3'- pyrophosphohydrolase complement(1826640..1828754) Haemophilus influenzae Rd KW20 950884 NP_439886.1 CDS rpoZ NC_000907.1 1828934 1829200 R promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1828934..1829200) Haemophilus influenzae Rd KW20 950552 NP_439887.1 CDS gmk NC_000907.1 1829263 1829889 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1829263..1829889) Haemophilus influenzae Rd KW20 950885 HI10044.1 tRNA HI10044.1 NC_000907.1 47152 47241 D tRNA-Ser 47152..47241 Haemophilus influenzae Rd KW20 950941 HI0086.2 tRNA HI0086.2 NC_000907.1 91546 91621 D tRNA-Gly 91546..91621 Haemophilus influenzae Rd KW20 950985 HI0086.1 tRNA tRNA-Cys-1 NC_000907.1 91628 91701 D tRNA-Cys 91628..91701 Haemophilus influenzae Rd KW20 950986 HI0086.3 tRNA HI0086.3 NC_000907.1 91729 91815 D tRNA-Leu 91729..91815 Haemophilus influenzae Rd KW20 950988 HI0086.4 tRNA HI0086.4 NC_000907.1 91866 91941 D tRNA-Lys 91866..91941 Haemophilus influenzae Rd KW20 950984 HI1003.4 tRNA tRNA-Glu-1 NC_000907.1 126969 127044 R tRNA-Glu complement(126969..127044) Haemophilus influenzae Rd KW20 951008 HI0113.6 tRNA tRNA-Pro-1 NC_000907.1 128892 128968 R tRNA-Pro complement(128892..128968) Haemophilus influenzae Rd KW20 951019 HI0113.7 tRNA tRNA-His-1 NC_000907.1 128990 129065 R tRNA-His complement(128990..129065) Haemophilus influenzae Rd KW20 951020 HI0113.8 tRNA tRNA-Arg-1 NC_000907.1 129092 129168 R tRNA-Arg complement(129092..129168) Haemophilus influenzae Rd KW20 951022 HI0116.1 tRNA tRNA-Met-1 NC_000907.1 131584 131660 R tRNA-Met complement(131584..131660) Haemophilus influenzae Rd KW20 951023 HI0123.1 tRNA HI0123.1 NC_000907.1 139513 139588 D tRNA-Gly 139513..139588 Haemophilus influenzae Rd KW20 951029 HI0123.2 tRNA HI0123.2 NC_000907.1 139593 139679 D tRNA-Leu 139593..139679 Haemophilus influenzae Rd KW20 951033 HI0123.3 tRNA HI0123.3 NC_000907.1 139730 139805 D tRNA-Lys 139730..139805 Haemophilus influenzae Rd KW20 951035 HI0136.1 tRNA tRNA-Asp-1 NC_000907.1 152228 152304 R tRNA-Asp complement(152228..152304) Haemophilus influenzae Rd KW20 951046 HI0136.2 tRNA HI0136.2 NC_000907.1 152328 152404 R tRNA-Asp complement(152328..152404) Haemophilus influenzae Rd KW20 951044 HI0220.6 tRNA HI0220.6 NC_000907.1 245806 245881 R tRNA-Glu complement(245806..245881) Haemophilus influenzae Rd KW20 951133 HI0247.1 tRNA tRNA-Ser-2 NC_000907.1 288153 288242 R tRNA-Ser complement(288153..288242) Haemophilus influenzae Rd KW20 949382 HI0273.1 tRNA tRNA-Ala-1 NC_000907.1 307279 307354 R tRNA-Ala complement(307279..307354) Haemophilus influenzae Rd KW20 950709 HI0274.1 tRNA HI0274.1 NC_000907.1 309048 309123 D tRNA-Val 309048..309123 Haemophilus influenzae Rd KW20 950310 HI0274.2 tRNA HI0274.2 NC_000907.1 309167 309242 D tRNA-Val 309167..309242 Haemophilus influenzae Rd KW20 949399 HI0274.3 tRNA HI0274.3 NC_000907.1 309301 309376 D tRNA-Val 309301..309376 Haemophilus influenzae Rd KW20 950777 HI0274.4 tRNA tRNA-Val-4 NC_000907.1 309429 309504 D tRNA-Val 309429..309504 Haemophilus influenzae Rd KW20 949496 HI0326.1 tRNA HI0326.1 NC_000907.1 355348 355437 R tRNA-Ser complement(355348..355437) Haemophilus influenzae Rd KW20 950059 HI0380.1 tRNA tRNA-Lys-3 NC_000907.1 401796 401871 R tRNA-Lys complement(401796..401871) Haemophilus influenzae Rd KW20 949584 HI0380.2 tRNA HI0380.2 NC_000907.1 401895 401970 R tRNA-Lys complement(401895..401970) Haemophilus influenzae Rd KW20 949483 HI0445.1 tRNA tRNA-Leu-3 NC_000907.1 467760 467842 D tRNA-Leu 467760..467842 Haemophilus influenzae Rd KW20 950732 HI0601.6 tRNA HI0601.6 NC_000907.1 625444 625520 D tRNA-Ile 625444..625520 Haemophilus influenzae Rd KW20 949649 HI0601.7 tRNA HI0601.7 NC_000907.1 625606 625681 D tRNA-Ala 625606..625681 Haemophilus influenzae Rd KW20 950686 HI0601.8 tRNA HI0601.8 NC_000907.1 629523 629599 D tRNA-Asp 629523..629599 Haemophilus influenzae Rd KW20 950586 HI0601.5 tRNA tRNA-Trp-1 NC_000907.1 629628 629703 D tRNA-Trp 629628..629703 Haemophilus influenzae Rd KW20 950135 HI0609.1 tRNA HI0609.1 NC_000907.1 641105 641181 D tRNA-Pro 641105..641181 Haemophilus influenzae Rd KW20 949662 HI0609.2 tRNA HI0609.2 NC_000907.1 641229 641305 D tRNA-Arg 641229..641305 Haemophilus influenzae Rd KW20 949999 HI0621.5 tRNA HI0621.5 NC_000907.1 658778 658853 D tRNA-Glu 658778..658853 Haemophilus influenzae Rd KW20 949760 HI0631.4 tRNA HI0631.4 NC_000907.1 671274 671349 D tRNA-Thr 671274..671349 Haemophilus influenzae Rd KW20 950723 HI0631.1 tRNA tRNA-Tyr-1 NC_000907.1 671379 671463 D tRNA-Tyr 671379..671463 Haemophilus influenzae Rd KW20 949685 HI0631.2 tRNA tRNA-Gly-3 NC_000907.1 671506 671580 D tRNA-Gly 671506..671580 Haemophilus influenzae Rd KW20 949743 HI0631.3 tRNA tRNA-Thr-2 NC_000907.1 671584 671659 D tRNA-Thr 671584..671659 Haemophilus influenzae Rd KW20 950677 HI0642.3 tRNA HI0642.3 NC_000907.1 684859 684935 R tRNA-Arg complement(684859..684935) Haemophilus influenzae Rd KW20 950736 HI0642.2 tRNA HI0642.2 NC_000907.1 684993 685069 R tRNA-Arg complement(684993..685069) Haemophilus influenzae Rd KW20 950816 HI0642.1 tRNA HI0642.1 NC_000907.1 685090 685184 R tRNA-Ser complement(685090..685184) Haemophilus influenzae Rd KW20 949692 HI0707.1 tRNA tRNA-SeC(p)-1 NC_000907.1 753791 753881 R tRNA-Sec complement(753791..753881) Haemophilus influenzae Rd KW20 949733 HI0723.2 tRNA tRNA-Ile-2 NC_000907.1 772829 772905 D tRNA-Ile 772829..772905 Haemophilus influenzae Rd KW20 949744 HI0723.5 tRNA HI0723.5 NC_000907.1 772991 773066 D tRNA-Ala 772991..773066 Haemophilus influenzae Rd KW20 949745 HI0761.1 tRNA HI0761.1 NC_000907.1 825313 825388 D tRNA-Phe 825313..825388 Haemophilus influenzae Rd KW20 949778 HI0761.2 tRNA HI0761.2 NC_000907.1 825391 825466 D tRNA-Asn 825391..825466 Haemophilus influenzae Rd KW20 949779 HI0923.1 tRNA HI0923.1 NC_000907.1 981435 981511 R tRNA-Met complement(981435..981511) Haemophilus influenzae Rd KW20 950667 HI1247.1 tRNA HI1247.1 NC_000907.1 1324965 1325040 D tRNA-Asn 1324965..1325040 Haemophilus influenzae Rd KW20 950627 HI1281.1 tRNA HI1281.1 NC_000907.1 1358358 1358434 D tRNA-Met 1358358..1358434 Haemophilus influenzae Rd KW20 950212 HI1424.1 tRNA HI1424.1 NC_000907.1 1513211 1513296 R tRNA-Leu complement(1513211..1513296) Haemophilus influenzae Rd KW20 950829 HI1502.1 tRNA HI1502.1 NC_000907.1 1576960 1577041 R tRNA-OTHER complement(1576960..1577041) Haemophilus influenzae Rd KW20 950370 HI1572.1 tRNA HI1572.1 NC_000907.1 1639927 1640003 R tRNA-Val complement(1639927..1640003) Haemophilus influenzae Rd KW20 950432 HI1631.4 tRNA HI1631.4 NC_000907.1 1693872 1693946 R tRNA-Gln complement(1693872..1693946) Haemophilus influenzae Rd KW20 950475 HI1631.3 tRNA HI1631.3 NC_000907.1 1693994 1694068 R tRNA-Gln complement(1693994..1694068) Haemophilus influenzae Rd KW20 950460 HI1631.2 tRNA HI1631.2 NC_000907.1 1694097 1694181 R tRNA-Leu complement(1694097..1694181) Haemophilus influenzae Rd KW20 950477 HI1631.1 tRNA HI1631.1 NC_000907.1 1694187 1694263 R tRNA-Met complement(1694187..1694263) Haemophilus influenzae Rd KW20 950480 HI1715.1 tRNA HI1715.1 NC_000907.1 1787881 1787956 D tRNA-Gly 1787881..1787956 Haemophilus influenzae Rd KW20 950532 HI1739.5 tRNA HI1739.5 NC_000907.1 1820143 1820218 R tRNA-Ala complement(1820143..1820218) Haemophilus influenzae Rd KW20 950551 HI1739.4 tRNA HI1739.4 NC_000907.1 1820304 1820380 R tRNA-Ile complement(1820304..1820380) Haemophilus influenzae Rd KW20 950542 HI0113.2 rRNA HIrrnE5S NC_000907.1 123431 123559 R 5S ribosomal RNA complement(123431..123559) Haemophilus influenzae Rd KW20 951012 HI0113.3 rRNA HIrrnE23S NC_000907.1 123800 126702 R 23S ribosomal RNA complement(123800..126702) Haemophilus influenzae Rd KW20 951017 HI1003.5 rRNA HIrrnE16S NC_000907.1 127172 128720 R 16S ribosomal RNA complement(127172..128720) Haemophilus influenzae Rd KW20 951018 HI0220.3 rRNA HIrrnF5S NC_000907.1 242269 242397 R 5S ribosomal RNA complement(242269..242397) Haemophilus influenzae Rd KW20 951130 HI0220.4 rRNA HIrrnF23S NC_000907.1 242637 245539 R 23S ribosomal RNA complement(242637..245539) Haemophilus influenzae Rd KW20 951132 HI0220.5 rRNA HIrrnF16S NC_000907.1 246009 247557 R 16S ribosomal RNA complement(246009..247557) Haemophilus influenzae Rd KW20 951135 HI0601.2 rRNA HIrrnA16S NC_000907.1 623821 625369 D 16S ribosomal RNA 623821..625369 Haemophilus influenzae Rd KW20 949648 HI0601.3 rRNA HIrrnA23S NC_000907.1 626083 628985 D 23S ribosomal RNA 626083..628985 Haemophilus influenzae Rd KW20 950825 HI0601.4 rRNA HIrrnA5S NC_000907.1 629226 629354 D 5S ribosomal RNA 629226..629354 Haemophilus influenzae Rd KW20 949481 HI0601.9 rRNA HI0601.9 NC_000907.1 629394 629512 D 5S ribosomal RNA 629394..629512 Haemophilus influenzae Rd KW20 5696428 HI0621.2 rRNA HIrrnB16S NC_000907.1 657103 658651 D 16S ribosomal RNA 657103..658651 Haemophilus influenzae Rd KW20 949676 HI0621.3 rRNA HIrrnB23S NC_000907.1 659120 662022 D 23S ribosomal RNA 659120..662022 Haemophilus influenzae Rd KW20 949677 HI0621.4 rRNA HIrrnB5S NC_000907.1 662263 662391 D 5S ribosomal RNA 662263..662391 Haemophilus influenzae Rd KW20 949972 HI0723.1 rRNA HIrrnC16S NC_000907.1 771206 772754 D 16S ribosomal RNA 771206..772754 Haemophilus influenzae Rd KW20 950730 HI0723.3 rRNA HIrrnC23S NC_000907.1 773468 776370 D 23S ribosomal RNA 773468..776370 Haemophilus influenzae Rd KW20 949747 HI0723.4 rRNA HIrrnC5S NC_000907.1 776611 776739 D 5S ribosomal RNA 776611..776739 Haemophilus influenzae Rd KW20 949748 HI1739.7 rRNA HIrrnD5S NC_000907.1 1816484 1816598 R 5S ribosomal RNA complement(1816484..1816598) Haemophilus influenzae Rd KW20 950546 HI1739.6 rRNA HIrrnD23S NC_000907.1 1816839 1819741 R 23S ribosomal RNA complement(1816839..1819741) Haemophilus influenzae Rd KW20 950547 HI1739.3 rRNA HIrrnD16S NC_000907.1 1820456 1822004 R 16S ribosomal RNA complement(1820456..1822004) Haemophilus influenzae Rd KW20 950548