-- dump date   	20140619_094336
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
755732000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
755732000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
755732000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732000004	Walker A motif; other site
755732000005	ATP binding site [chemical binding]; other site
755732000006	Walker B motif; other site
755732000007	arginine finger; other site
755732000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
755732000009	DnaA box-binding interface [nucleotide binding]; other site
755732000010	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732000011	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732000012	Active site serine [active]
755732000013	Uncharacterized conserved protein [Function unknown]; Region: COG1739
755732000014	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
755732000015	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
755732000016	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
755732000017	metal binding site [ion binding]; metal-binding site
755732000018	flavoprotein, HI0933 family; Region: TIGR00275
755732000019	Propeptide_C25; Region: Propeptide_C25; pfam08126
755732000020	gingipain subgroup of the Peptidase C25 family N-terminal domain; Region: Peptidase_C25_N_gingipain; cd10913
755732000021	active site
755732000022	Peptidase family C25, C terminal ig-like domain; Region: Peptidase_C25_C; pfam03785
755732000023	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000024	conserved hypothetical protein; Region: TIGR02231
755732000025	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
755732000026	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
755732000027	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
755732000028	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
755732000029	active site
755732000030	substrate binding site [chemical binding]; other site
755732000031	metal binding site [ion binding]; metal-binding site
755732000032	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
755732000033	homopentamer interface [polypeptide binding]; other site
755732000034	active site
755732000035	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732000036	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732000037	TPR motif; other site
755732000038	binding surface
755732000039	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000040	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
755732000041	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732000042	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
755732000043	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
755732000044	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
755732000045	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000046	Predicted transcriptional regulators [Transcription]; Region: COG1510
755732000047	MarR family; Region: MarR_2; cl17246
755732000048	Protein of unknown function, DUF393; Region: DUF393; cl01136
755732000049	Tandem repeat subunit of reelin and related proteins; Region: Reelin_subrepeat_like; cl15240
755732000050	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
755732000051	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732000052	Uncharacterized conserved protein [Function unknown]; Region: COG1434
755732000053	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
755732000054	putative active site [active]
755732000055	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732000056	Enoyl-(Acyl carrier protein) reductase; Region: adh_short_C2; pfam13561
755732000057	NAD(P) binding site [chemical binding]; other site
755732000058	active site
755732000059	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
755732000060	putative hydrolase; Provisional; Region: PRK02113
755732000061	Protein of unknown function (DUF423); Region: DUF423; pfam04241
755732000062	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
755732000063	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
755732000064	Walker A/P-loop; other site
755732000065	ATP binding site [chemical binding]; other site
755732000066	Q-loop/lid; other site
755732000067	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
755732000068	ABC transporter signature motif; other site
755732000069	Walker B; other site
755732000070	D-loop; other site
755732000071	H-loop/switch region; other site
755732000072	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
755732000073	Flavoprotein; Region: Flavoprotein; pfam02441
755732000074	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
755732000075	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
755732000076	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
755732000077	active site
755732000078	nucleophile elbow; other site
755732000079	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
755732000080	Peptidase family M23; Region: Peptidase_M23; pfam01551
755732000081	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732000082	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732000083	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732000084	peptidyl-prolyl isomerase, gliding motility-associated; Region: ppisom_GldI; TIGR03516
755732000085	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732000086	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
755732000087	DHH family; Region: DHH; pfam01368
755732000088	DHHA1 domain; Region: DHHA1; pfam02272
755732000089	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
755732000090	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
755732000091	dimer interface [polypeptide binding]; other site
755732000092	active site
755732000093	catalytic residue [active]
755732000094	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
755732000095	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
755732000096	nucleotide binding pocket [chemical binding]; other site
755732000097	K-X-D-G motif; other site
755732000098	catalytic site [active]
755732000099	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
755732000100	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
755732000101	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
755732000102	Dimer interface [polypeptide binding]; other site
755732000103	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
755732000104	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
755732000105	active site
755732000106	Protein of unknown function (DUF1271); Region: DUF1271; pfam06902
755732000107	CDGSH-type zinc finger. Function unknown; Region: ZnF_CDGSH; smart00704
755732000108	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
755732000109	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732000110	S-adenosylmethionine binding site [chemical binding]; other site
755732000111	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
755732000112	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732000113	methionine sulfoxide reductase B; Provisional; Region: PRK05508
755732000114	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
755732000115	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732000116	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732000117	catalytic residues [active]
755732000118	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
755732000119	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
755732000120	hinge; other site
755732000121	active site
755732000122	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
755732000123	Predicted membrane protein (DUF2306); Region: DUF2306; pfam10067
755732000124	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732000125	TPR motif; other site
755732000126	TPR repeat; Region: TPR_11; pfam13414
755732000127	binding surface
755732000128	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
755732000129	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000130	Penicillinase repressor; Region: Pencillinase_R; pfam03965
755732000131	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
755732000132	Gram-negative bacterial tonB protein; Region: TonB; cl10048
755732000133	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
755732000134	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
755732000135	Divergent AAA domain; Region: AAA_4; pfam04326
755732000136	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
755732000137	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
755732000138	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
755732000139	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
755732000140	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732000141	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732000142	NAD(P) binding site [chemical binding]; other site
755732000143	active site
755732000144	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
755732000145	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732000146	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000147	active site
755732000148	phosphorylation site [posttranslational modification]
755732000149	intermolecular recognition site; other site
755732000150	dimerization interface [polypeptide binding]; other site
755732000151	LytTr DNA-binding domain; Region: LytTR; smart00850
755732000152	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732000153	Histidine kinase; Region: His_kinase; pfam06580
755732000154	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732000155	ATP binding site [chemical binding]; other site
755732000156	Mg2+ binding site [ion binding]; other site
755732000157	G-X-G motif; other site
755732000158	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732000159	PKD domain; Region: PKD; pfam00801
755732000160	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732000161	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732000162	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
755732000163	heme-binding site [chemical binding]; other site
755732000164	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
755732000165	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
755732000166	trimer interface [polypeptide binding]; other site
755732000167	putative metal binding site [ion binding]; other site
755732000168	Transcriptional regulator [Transcription]; Region: LysR; COG0583
755732000169	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
755732000170	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
755732000171	dimerization interface [polypeptide binding]; other site
755732000172	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
755732000173	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
755732000174	dimerization interface [polypeptide binding]; other site
755732000175	DPS ferroxidase diiron center [ion binding]; other site
755732000176	ion pore; other site
755732000177	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
755732000178	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
755732000179	dimer interface [polypeptide binding]; other site
755732000180	decamer (pentamer of dimers) interface [polypeptide binding]; other site
755732000181	catalytic triad [active]
755732000182	peroxidatic and resolving cysteines [active]
755732000183	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732000184	catalytic residues [active]
755732000185	vitamin B12-dependent ribonucleotide reductase; Validated; Region: PRK06556
755732000186	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
755732000187	DNA-binding site [nucleotide binding]; DNA binding site
755732000188	RNA-binding motif; other site
755732000189	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
755732000190	DNA-binding site [nucleotide binding]; DNA binding site
755732000191	RNA-binding motif; other site
755732000192	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
755732000193	Phage Tail Collar Domain; Region: Collar; pfam07484
755732000194	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
755732000195	Phage Tail Collar Domain; Region: Collar; pfam07484
755732000196	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
755732000197	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
755732000198	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
755732000199	active site
755732000200	substrate binding site [chemical binding]; other site
755732000201	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
755732000202	cosubstrate binding site; other site
755732000203	catalytic site [active]
755732000204	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
755732000205	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000206	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000207	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000208	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000209	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000210	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000211	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000212	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000213	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000214	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000215	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732000216	TPR motif; other site
755732000217	TPR repeat; Region: TPR_11; pfam13414
755732000218	binding surface
755732000219	TPR repeat; Region: TPR_11; pfam13414
755732000220	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732000221	binding surface
755732000222	TPR motif; other site
755732000223	TPR repeat; Region: TPR_11; pfam13414
755732000224	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732000225	TPR repeat; Region: TPR_11; pfam13414
755732000226	binding surface
755732000227	TPR motif; other site
755732000228	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
755732000229	Predicted transcriptional regulators [Transcription]; Region: COG1695
755732000230	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
755732000231	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
755732000232	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732000233	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732000234	ligand binding site [chemical binding]; other site
755732000235	flexible hinge region; other site
755732000236	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
755732000237	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR1; cd08267
755732000238	putative NAD(P) binding site [chemical binding]; other site
755732000239	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
755732000240	active site
755732000241	phytoene desaturase; Region: crtI_fam; TIGR02734
755732000242	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732000243	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732000244	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000245	active site
755732000246	phosphorylation site [posttranslational modification]
755732000247	intermolecular recognition site; other site
755732000248	dimerization interface [polypeptide binding]; other site
755732000249	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732000250	DNA binding site [nucleotide binding]
755732000251	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
755732000252	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732000253	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732000254	ATP binding site [chemical binding]; other site
755732000255	Mg2+ binding site [ion binding]; other site
755732000256	G-X-G motif; other site
755732000257	Outer membrane efflux protein; Region: OEP; pfam02321
755732000258	Outer membrane efflux protein; Region: OEP; pfam02321
755732000259	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732000260	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732000261	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732000262	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
755732000263	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732000264	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732000265	Methyltransferase domain; Region: Methyltransf_23; pfam13489
755732000266	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732000267	S-adenosylmethionine binding site [chemical binding]; other site
755732000268	diaminopimelate decarboxylase; Region: lysA; TIGR01048
755732000269	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
755732000270	active site
755732000271	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
755732000272	substrate binding site [chemical binding]; other site
755732000273	catalytic residues [active]
755732000274	dimer interface [polypeptide binding]; other site
755732000275	conserved hypothetical protein; Region: TIGR02231
755732000276	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
755732000277	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
755732000278	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
755732000279	legume lectins; Region: lectin_L-type; cd01951
755732000280	homotetramer interaction site [polypeptide binding]; other site
755732000281	carbohydrate binding site [chemical binding]; other site
755732000282	metal binding site [ion binding]; metal-binding site
755732000283	Transcriptional regulators [Transcription]; Region: PurR; COG1609
755732000284	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
755732000285	DNA binding site [nucleotide binding]
755732000286	domain linker motif; other site
755732000287	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
755732000288	dimerization interface [polypeptide binding]; other site
755732000289	ligand binding site [chemical binding]; other site
755732000290	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
755732000291	ATP-NAD kinase; Region: NAD_kinase; pfam01513
755732000292	FOG: CBS domain [General function prediction only]; Region: COG0517
755732000293	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
755732000294	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
755732000295	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
755732000296	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732000297	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000298	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
755732000299	putative active site [active]
755732000300	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
755732000301	active site
755732000302	hydrophilic channel; other site
755732000303	dimerization interface [polypeptide binding]; other site
755732000304	catalytic residues [active]
755732000305	active site lid [active]
755732000306	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
755732000307	PGAP1-like protein; Region: PGAP1; pfam07819
755732000308	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732000309	Protein export membrane protein; Region: SecD_SecF; cl14618
755732000310	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732000311	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732000312	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732000313	Outer membrane efflux protein; Region: OEP; pfam02321
755732000314	Outer membrane efflux protein; Region: OEP; pfam02321
755732000315	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
755732000316	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
755732000317	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
755732000318	EamA-like transporter family; Region: EamA; pfam00892
755732000319	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
755732000320	Protein of unknown function DUF58; Region: DUF58; pfam01882
755732000321	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
755732000322	Methyltransferase domain; Region: Methyltransf_24; pfam13578
755732000323	cytochrome c-550; Provisional; Region: psbV; cl17239
755732000324	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
755732000325	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
755732000326	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732000327	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732000328	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732000329	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732000330	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
755732000331	Family description; Region: VCBS; pfam13517
755732000332	Family description; Region: VCBS; pfam13517
755732000333	Family description; Region: VCBS; pfam13517
755732000334	Family description; Region: VCBS; pfam13517
755732000335	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000336	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000337	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732000338	NAD(P) binding site [chemical binding]; other site
755732000339	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732000340	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
755732000341	active site
755732000342	Uncharacterized conserved protein [Function unknown]; Region: COG2454
755732000343	GTP-binding protein YchF; Reviewed; Region: PRK09601
755732000344	YchF GTPase; Region: YchF; cd01900
755732000345	G1 box; other site
755732000346	GTP/Mg2+ binding site [chemical binding]; other site
755732000347	Switch I region; other site
755732000348	G2 box; other site
755732000349	Switch II region; other site
755732000350	G3 box; other site
755732000351	G4 box; other site
755732000352	G5 box; other site
755732000353	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
755732000354	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000355	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
755732000356	PA_M28_2: Protease-associated (PA) domain, peptidase family M28, subfamily-2. A subfamily of PA-domain containing proteins belonging to the peptidase family M28. Family M28 contains aminopeptidases and carboxypeptidases, and has co-catalytic zinc ions; Region: PA_M28_2; cd04815
755732000357	PA/protease or protease-like domain interface [polypeptide binding]; other site
755732000358	M28 Zn-Peptidase Plasma glutamate carboxypeptidase; Region: M28_Pgcp_like; cd03883
755732000359	Peptidase family M28; Region: Peptidase_M28; pfam04389
755732000360	metal binding site [ion binding]; metal-binding site
755732000361	DinB superfamily; Region: DinB_2; pfam12867
755732000362	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
755732000363	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
755732000364	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732000365	catalytic residue [active]
755732000366	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732000367	Histidine kinase; Region: HisKA_2; pfam07568
755732000368	MarC family integral membrane protein; Region: MarC; cl00919
755732000369	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732000370	OsmC-like protein; Region: OsmC; cl00767
755732000371	HPP family; Region: HPP; pfam04982
755732000372	hypothetical protein; Provisional; Region: PRK07758
755732000373	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
755732000374	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
755732000375	Zn binding site [ion binding]; other site
755732000376	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
755732000377	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
755732000378	Periplasmic lysozyme inhibitor, I-type (PliI) and similar proteins; Region: PliI_like; cd09632
755732000379	putative inhibitory loop; other site
755732000380	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
755732000381	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
755732000382	active site
755732000383	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
755732000384	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
755732000385	active site
755732000386	putative DNA-binding cleft [nucleotide binding]; other site
755732000387	dimer interface [polypeptide binding]; other site
755732000388	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
755732000389	dihydroorotase; Reviewed; Region: PRK09236
755732000390	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
755732000391	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
755732000392	active site
755732000393	D-aminoacylase, C-terminal region; Region: D-aminoacyl_C; pfam07908
755732000394	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
755732000395	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
755732000396	Ligand binding site; other site
755732000397	Putative Catalytic site; other site
755732000398	DXD motif; other site
755732000399	choice-of-anchor B domain; Region: choice_anch_B; TIGR04312
755732000400	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000401	recombination regulator RecX; Reviewed; Region: recX; PRK00117
755732000402	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
755732000403	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
755732000404	homodimer interface [polypeptide binding]; other site
755732000405	oligonucleotide binding site [chemical binding]; other site
755732000406	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
755732000407	IHF - DNA interface [nucleotide binding]; other site
755732000408	IHF dimer interface [polypeptide binding]; other site
755732000409	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
755732000410	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
755732000411	minor groove reading motif; other site
755732000412	helix-hairpin-helix signature motif; other site
755732000413	substrate binding pocket [chemical binding]; other site
755732000414	active site
755732000415	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
755732000416	DNA binding and oxoG recognition site [nucleotide binding]
755732000417	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
755732000418	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
755732000419	dimer interface [polypeptide binding]; other site
755732000420	ssDNA binding site [nucleotide binding]; other site
755732000421	tetramer (dimer of dimers) interface [polypeptide binding]; other site
755732000422	Domain of unknown function DUF21; Region: DUF21; pfam01595
755732000423	gliding motility-associated protein GldE; Region: GldE; TIGR03520
755732000424	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
755732000425	Transporter associated domain; Region: CorC_HlyC; smart01091
755732000426	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
755732000427	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
755732000428	active site
755732000429	Zn binding site [ion binding]; other site
755732000430	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
755732000431	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
755732000432	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
755732000433	Divergent AAA domain; Region: AAA_4; pfam04326
755732000434	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
755732000435	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
755732000436	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
755732000437	shikimate binding site; other site
755732000438	NAD(P) binding site [chemical binding]; other site
755732000439	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
755732000440	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
755732000441	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732000442	active site residue [active]
755732000443	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
755732000444	active site 2 [active]
755732000445	active site 1 [active]
755732000446	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
755732000447	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
755732000448	FMN binding site [chemical binding]; other site
755732000449	substrate binding site [chemical binding]; other site
755732000450	putative catalytic residue [active]
755732000451	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
755732000452	UbiA prenyltransferase family; Region: UbiA; pfam01040
755732000453	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
755732000454	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
755732000455	active site
755732000456	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
755732000457	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
755732000458	FMN binding site [chemical binding]; other site
755732000459	substrate binding site [chemical binding]; other site
755732000460	putative catalytic residue [active]
755732000461	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
755732000462	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
755732000463	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
755732000464	nucleotide binding site [chemical binding]; other site
755732000465	NEF interaction site [polypeptide binding]; other site
755732000466	SBD interface [polypeptide binding]; other site
755732000467	amino acid transporter; Region: 2A0306; TIGR00909
755732000468	amino acid transporter; Region: 2A0306; TIGR00909
755732000469	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
755732000470	ABC1 family; Region: ABC1; cl17513
755732000471	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
755732000472	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
755732000473	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732000474	Walker A/P-loop; other site
755732000475	ATP binding site [chemical binding]; other site
755732000476	Q-loop/lid; other site
755732000477	ABC transporter signature motif; other site
755732000478	Walker B; other site
755732000479	D-loop; other site
755732000480	H-loop/switch region; other site
755732000481	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
755732000482	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
755732000483	motif 1; other site
755732000484	active site
755732000485	motif 2; other site
755732000486	motif 3; other site
755732000487	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
755732000488	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732000489	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
755732000490	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732000491	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
755732000492	NAD binding site [chemical binding]; other site
755732000493	homotetramer interface [polypeptide binding]; other site
755732000494	homodimer interface [polypeptide binding]; other site
755732000495	active site
755732000496	substrate binding site [chemical binding]; other site
755732000497	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732000498	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
755732000499	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
755732000500	NAD(P) binding site [chemical binding]; other site
755732000501	homodimer interface [polypeptide binding]; other site
755732000502	substrate binding site [chemical binding]; other site
755732000503	active site
755732000504	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
755732000505	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
755732000506	inhibitor-cofactor binding pocket; inhibition site
755732000507	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732000508	catalytic residue [active]
755732000509	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
755732000510	ligand binding site; other site
755732000511	tetramer interface; other site
755732000512	Methyltransferase domain; Region: Methyltransf_23; pfam13489
755732000513	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732000514	S-adenosylmethionine binding site [chemical binding]; other site
755732000515	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
755732000516	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732000517	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732000518	NAD(P) binding site [chemical binding]; other site
755732000519	active site
755732000520	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
755732000521	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732000522	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
755732000523	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
755732000524	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
755732000525	pseudaminic acid synthase; Region: PseI; TIGR03586
755732000526	NeuB family; Region: NeuB; pfam03102
755732000527	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
755732000528	NeuB binding interface [polypeptide binding]; other site
755732000529	putative substrate binding site [chemical binding]; other site
755732000530	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
755732000531	Response regulator receiver domain; Region: Response_reg; pfam00072
755732000532	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000533	active site
755732000534	phosphorylation site [posttranslational modification]
755732000535	intermolecular recognition site; other site
755732000536	dimerization interface [polypeptide binding]; other site
755732000537	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732000538	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
755732000539	Walker A motif; other site
755732000540	ATP binding site [chemical binding]; other site
755732000541	Walker B motif; other site
755732000542	arginine finger; other site
755732000543	exopolyphosphatase; Region: exo_poly_only; TIGR03706
755732000544	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
755732000545	nucleotide binding site [chemical binding]; other site
755732000546	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
755732000547	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
755732000548	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732000549	Walker A/P-loop; other site
755732000550	ATP binding site [chemical binding]; other site
755732000551	Q-loop/lid; other site
755732000552	ABC transporter signature motif; other site
755732000553	Walker B; other site
755732000554	D-loop; other site
755732000555	H-loop/switch region; other site
755732000556	CAAX protease self-immunity; Region: Abi; pfam02517
755732000557	chaperone protein DnaJ; Provisional; Region: PRK14289
755732000558	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732000559	HSP70 interaction site [polypeptide binding]; other site
755732000560	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
755732000561	substrate binding site [polypeptide binding]; other site
755732000562	dimer interface [polypeptide binding]; other site
755732000563	GrpE; Region: GrpE; pfam01025
755732000564	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
755732000565	dimer interface [polypeptide binding]; other site
755732000566	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
755732000567	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
755732000568	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
755732000569	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
755732000570	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732000571	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
755732000572	dimer interface [polypeptide binding]; other site
755732000573	phosphorylation site [posttranslational modification]
755732000574	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732000575	ATP binding site [chemical binding]; other site
755732000576	Mg2+ binding site [ion binding]; other site
755732000577	G-X-G motif; other site
755732000578	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732000579	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000580	active site
755732000581	phosphorylation site [posttranslational modification]
755732000582	intermolecular recognition site; other site
755732000583	dimerization interface [polypeptide binding]; other site
755732000584	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732000585	DNA binding site [nucleotide binding]
755732000586	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
755732000587	Sulfatase; Region: Sulfatase; cl17466
755732000588	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
755732000589	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
755732000590	FeS/SAM binding site; other site
755732000591	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
755732000592	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
755732000593	substrate binding pocket [chemical binding]; other site
755732000594	chain length determination region; other site
755732000595	substrate-Mg2+ binding site; other site
755732000596	catalytic residues [active]
755732000597	aspartate-rich region 1; other site
755732000598	active site lid residues [active]
755732000599	aspartate-rich region 2; other site
755732000600	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732000601	DNA primase, catalytic core; Region: dnaG; TIGR01391
755732000602	CHC2 zinc finger; Region: zf-CHC2; pfam01807
755732000603	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
755732000604	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
755732000605	active site
755732000606	metal binding site [ion binding]; metal-binding site
755732000607	interdomain interaction site; other site
755732000608	Mechanosensitive ion channel; Region: MS_channel; pfam00924
755732000609	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
755732000610	dimer interface [polypeptide binding]; other site
755732000611	substrate binding site [chemical binding]; other site
755732000612	metal binding sites [ion binding]; metal-binding site
755732000613	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
755732000614	TPR repeat; Region: TPR_11; pfam13414
755732000615	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732000616	binding surface
755732000617	TPR motif; other site
755732000618	Alg9-like mannosyltransferase family; Region: Glyco_transf_22; cl17751
755732000619	Alg9-like mannosyltransferase family; Region: Glyco_transf_22; cl17751
755732000620	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
755732000621	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
755732000622	metal ion-dependent adhesion site (MIDAS); other site
755732000623	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000624	Response regulator receiver domain; Region: Response_reg; pfam00072
755732000625	active site
755732000626	phosphorylation site [posttranslational modification]
755732000627	intermolecular recognition site; other site
755732000628	dimerization interface [polypeptide binding]; other site
755732000629	Uncharacterized conserved protein [Function unknown]; Region: COG2353
755732000630	Uncharacterized conserved protein [Function unknown]; Region: COG2353
755732000631	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
755732000632	Transposase; Region: DDE_Tnp_ISL3; pfam01610
755732000633	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
755732000634	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
755732000635	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
755732000636	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
755732000637	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
755732000638	active site
755732000639	metal binding site [ion binding]; metal-binding site
755732000640	Bacterial sugar transferase; Region: Bac_transf; pfam02397
755732000641	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
755732000642	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
755732000643	putative NADP binding site [chemical binding]; other site
755732000644	putative substrate binding site [chemical binding]; other site
755732000645	active site
755732000646	3-oxo-5-alpha-steroid 4-dehydrogenase; Region: Steroid_dh; cl17474
755732000647	Domain of unknown function (DUF4135); Region: DUF4135; pfam13575
755732000648	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
755732000649	TRAM domain; Region: TRAM; pfam01938
755732000650	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732000651	S-adenosylmethionine binding site [chemical binding]; other site
755732000652	Rrf2 family protein; Region: rrf2_super; TIGR00738
755732000653	Transcriptional regulator; Region: Rrf2; pfam02082
755732000654	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
755732000655	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
755732000656	active site
755732000657	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
755732000658	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
755732000659	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
755732000660	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
755732000661	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
755732000662	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
755732000663	trimer interface [polypeptide binding]; other site
755732000664	active site
755732000665	UDP-GlcNAc binding site [chemical binding]; other site
755732000666	lipid binding site [chemical binding]; lipid-binding site
755732000667	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732000668	catalytic residues [active]
755732000669	Protein of unknown function (DUF493); Region: DUF493; pfam04359
755732000670	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
755732000671	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
755732000672	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
755732000673	dimer interface [polypeptide binding]; other site
755732000674	tetramer interface [polypeptide binding]; other site
755732000675	PYR/PP interface [polypeptide binding]; other site
755732000676	TPP binding site [chemical binding]; other site
755732000677	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
755732000678	TPP-binding site; other site
755732000679	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
755732000680	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
755732000681	CoenzymeA binding site [chemical binding]; other site
755732000682	subunit interaction site [polypeptide binding]; other site
755732000683	PHB binding site; other site
755732000684	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732000685	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
755732000686	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
755732000687	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732000688	Active site serine [active]
755732000689	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
755732000690	Found in ATP-dependent protease La (LON); Region: LON; smart00464
755732000691	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732000692	Walker A motif; other site
755732000693	ATP binding site [chemical binding]; other site
755732000694	Walker B motif; other site
755732000695	arginine finger; other site
755732000696	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
755732000697	Fatty acid desaturase; Region: FA_desaturase; pfam00487
755732000698	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
755732000699	putative di-iron ligands [ion binding]; other site
755732000700	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
755732000701	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732000702	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732000703	ligand binding site [chemical binding]; other site
755732000704	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
755732000705	23S rRNA binding site [nucleotide binding]; other site
755732000706	L21 binding site [polypeptide binding]; other site
755732000707	L13 binding site [polypeptide binding]; other site
755732000708	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
755732000709	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
755732000710	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
755732000711	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
755732000712	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
755732000713	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
755732000714	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
755732000715	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
755732000716	active site
755732000717	dimer interface [polypeptide binding]; other site
755732000718	motif 1; other site
755732000719	motif 2; other site
755732000720	motif 3; other site
755732000721	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
755732000722	anticodon binding site; other site
755732000723	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
755732000724	Competence protein; Region: Competence; pfam03772
755732000725	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
755732000726	putative ligand binding site [chemical binding]; other site
755732000727	EamA-like transporter family; Region: EamA; pfam00892
755732000728	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
755732000729	EamA-like transporter family; Region: EamA; pfam00892
755732000730	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
755732000731	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
755732000732	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
755732000733	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
755732000734	Ribokinase-like subgroup C.  Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_C; cd01946
755732000735	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
755732000736	substrate binding site [chemical binding]; other site
755732000737	ATP binding site [chemical binding]; other site
755732000738	von Willebrand factor type D domain; Region: VWD; cl02516
755732000739	AsmA family; Region: AsmA; pfam05170
755732000740	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
755732000741	MarC family integral membrane protein; Region: MarC; pfam01914
755732000742	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
755732000743	putative hydrophobic ligand binding site [chemical binding]; other site
755732000744	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732000745	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
755732000746	metal ion-dependent adhesion site (MIDAS); other site
755732000747	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000748	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732000749	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732000750	DNA binding residues [nucleotide binding]
755732000751	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
755732000752	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; cl01409
755732000753	Peptide-N-glycosidase F, N terminal; Region: N-glycanase_N; pfam09112
755732000754	Peptide-N-glycosidase F, C terminal; Region: N-glycanase_C; pfam09113
755732000755	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000756	fumarate hydratase; Reviewed; Region: fumC; PRK00485
755732000757	Class II fumarases; Region: Fumarase_classII; cd01362
755732000758	active site
755732000759	tetramer interface [polypeptide binding]; other site
755732000760	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
755732000761	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000762	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
755732000763	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
755732000764	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
755732000765	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000766	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
755732000767	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
755732000768	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
755732000769	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
755732000770	active site
755732000771	substrate binding site [chemical binding]; other site
755732000772	Mg2+ binding site [ion binding]; other site
755732000773	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732000774	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: alt_bact_glmU; TIGR03991
755732000775	Sugar nucleotidyl transferase; Region: NTP_transf_4; pfam13562
755732000776	Uncharacterized proteins, Left-handed parallel beta-Helix (LbH) domain: Members in this group are uncharacterized bacterial proteins containing a LbH domain with multiple turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif...; Region: LbH_unknown; cd05635
755732000777	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
755732000778	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
755732000779	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732000780	motif II; other site
755732000781	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
755732000782	Na binding site [ion binding]; other site
755732000783	trigger factor; Region: tig; TIGR00115
755732000784	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
755732000785	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
755732000786	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
755732000787	Histidine kinase; Region: His_kinase; pfam06580
755732000788	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732000789	MarR family; Region: MarR; pfam01047
755732000790	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732000791	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732000792	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732000793	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732000794	Protein export membrane protein; Region: SecD_SecF; cl14618
755732000795	Outer membrane efflux protein; Region: OEP; pfam02321
755732000796	Outer membrane efflux protein; Region: OEP; pfam02321
755732000797	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732000798	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000799	active site
755732000800	phosphorylation site [posttranslational modification]
755732000801	intermolecular recognition site; other site
755732000802	dimerization interface [polypeptide binding]; other site
755732000803	LytTr DNA-binding domain; Region: LytTR; smart00850
755732000804	Sulfatase; Region: Sulfatase; cl17466
755732000805	SEC-C motif; Region: SEC-C; pfam02810
755732000806	hypothetical protein; Provisional; Region: PRK04233
755732000807	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732000808	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732000809	GldM C-terminal domain; Region: GldM_C; pfam12080
755732000810	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732000811	helicase 45; Provisional; Region: PTZ00424
755732000812	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
755732000813	ATP binding site [chemical binding]; other site
755732000814	Mg++ binding site [ion binding]; other site
755732000815	motif III; other site
755732000816	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732000817	nucleotide binding region [chemical binding]; other site
755732000818	ATP-binding site [chemical binding]; other site
755732000819	fumarate hydratase; Provisional; Region: PRK15389
755732000820	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
755732000821	Fumarase C-terminus; Region: Fumerase_C; pfam05683
755732000822	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
755732000823	GIY-YIG motif/motif A; other site
755732000824	putative active site [active]
755732000825	putative metal binding site [ion binding]; other site
755732000826	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732000827	ATP binding site [chemical binding]; other site
755732000828	Mg2+ binding site [ion binding]; other site
755732000829	G-X-G motif; other site
755732000830	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
755732000831	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
755732000832	putative active site [active]
755732000833	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
755732000834	Zn binding site [ion binding]; other site
755732000835	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
755732000836	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
755732000837	Cl- selectivity filter; other site
755732000838	Cl- binding residues [ion binding]; other site
755732000839	pore gating glutamate residue; other site
755732000840	dimer interface [polypeptide binding]; other site
755732000841	FOG: CBS domain [General function prediction only]; Region: COG0517
755732000842	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
755732000843	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732000844	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
755732000845	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
755732000846	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
755732000847	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
755732000848	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
755732000849	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
755732000850	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
755732000851	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
755732000852	FMN binding site [chemical binding]; other site
755732000853	substrate binding site [chemical binding]; other site
755732000854	putative catalytic residue [active]
755732000855	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
755732000856	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732000857	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
755732000858	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732000859	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732000860	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732000861	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732000862	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732000863	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732000864	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732000865	TPR motif; other site
755732000866	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000867	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
755732000868	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
755732000869	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732000870	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
755732000871	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
755732000872	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
755732000873	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732000874	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
755732000875	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
755732000876	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
755732000877	Ligand Binding Site [chemical binding]; other site
755732000878	TilS substrate C-terminal domain; Region: TilS_C; smart00977
755732000879	salicylate synthase; Region: salicyl_syn; TIGR03494
755732000880	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
755732000881	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
755732000882	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Region: LPLAT_AAK14816-like; cd07992
755732000883	putative acyl-acceptor binding pocket; other site
755732000884	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732000885	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732000886	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732000887	binding surface
755732000888	TPR motif; other site
755732000889	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732000890	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732000891	Histidine kinase; Region: HisKA_3; pfam07730
755732000892	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732000893	ATP binding site [chemical binding]; other site
755732000894	Mg2+ binding site [ion binding]; other site
755732000895	G-X-G motif; other site
755732000896	Caspase domain; Region: Peptidase_C14; pfam00656
755732000897	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
755732000898	metal binding triad [ion binding]; metal-binding site
755732000899	2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; Region: OAS1_C; pfam10421
755732000900	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
755732000901	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732000902	Walker A motif; other site
755732000903	ATP binding site [chemical binding]; other site
755732000904	Walker B motif; other site
755732000905	arginine finger; other site
755732000906	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
755732000907	active site
755732000908	NTP binding site [chemical binding]; other site
755732000909	metal binding triad [ion binding]; metal-binding site
755732000910	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
755732000911	active site
755732000912	nucleophile elbow; other site
755732000913	Putative Ser protein kinase [Signal transduction mechanisms]; Region: PrkA; COG2766
755732000914	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
755732000915	non-specific DNA binding site [nucleotide binding]; other site
755732000916	salt bridge; other site
755732000917	sequence-specific DNA binding site [nucleotide binding]; other site
755732000918	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732000919	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
755732000920	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
755732000921	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732000922	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732000923	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
755732000924	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
755732000925	active site
755732000926	DNA binding site [nucleotide binding]
755732000927	Int/Topo IB signature motif; other site
755732000928	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
755732000929	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
755732000930	catalytic residues [active]
755732000931	catalytic nucleophile [active]
755732000932	Recombinase; Region: Recombinase; pfam07508
755732000933	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732000934	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732000935	non-specific DNA binding site [nucleotide binding]; other site
755732000936	salt bridge; other site
755732000937	sequence-specific DNA binding site [nucleotide binding]; other site
755732000938	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
755732000939	SIR2-like domain; Region: SIR2_2; pfam13289
755732000940	Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs; Region: Piwi_piwi-like_ProArk; cd04659
755732000941	5' RNA guide strand anchoring site; other site
755732000942	active site
755732000943	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
755732000944	putative active site [active]
755732000945	putative NTP binding site [chemical binding]; other site
755732000946	putative nucleic acid binding site [nucleotide binding]; other site
755732000947	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
755732000948	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
755732000949	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732000950	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732000951	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
755732000952	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
755732000953	Peptidase family M28; Region: Peptidase_M28; pfam04389
755732000954	metal binding site [ion binding]; metal-binding site
755732000955	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000956	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
755732000957	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
755732000958	Soluble P-type ATPase [General function prediction only]; Region: COG4087
755732000959	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732000960	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732000961	catalytic residues [active]
755732000962	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
755732000963	Protein of unknown function (DUF3703); Region: DUF3703; pfam12487
755732000964	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732000965	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732000966	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732000967	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
755732000968	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
755732000969	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
755732000970	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732000971	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732000972	dimer interface [polypeptide binding]; other site
755732000973	phosphorylation site [posttranslational modification]
755732000974	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732000975	ATP binding site [chemical binding]; other site
755732000976	Mg2+ binding site [ion binding]; other site
755732000977	G-X-G motif; other site
755732000978	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732000979	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732000980	active site
755732000981	phosphorylation site [posttranslational modification]
755732000982	intermolecular recognition site; other site
755732000983	dimerization interface [polypeptide binding]; other site
755732000984	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732000985	DNA binding site [nucleotide binding]
755732000986	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
755732000987	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732000988	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732000989	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732000990	MerC mercury resistance protein; Region: MerC; cl03934
755732000991	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
755732000992	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
755732000993	Transposase; Region: HTH_Tnp_1; cl17663
755732000994	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732000995	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732000996	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732000997	HD domain; Region: HD_3; pfam13023
755732000998	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732000999	Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681
755732001000	active site
755732001001	Domain of unknown function (DUF2383); Region: DUF2383; pfam09537
755732001002	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
755732001003	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
755732001004	Escherichia coli Mg2+ transporter CorA_like subfamily; Region: EcCorA-like; cd12825
755732001005	Cl binding site [ion binding]; other site
755732001006	oligomer interface [polypeptide binding]; other site
755732001007	acyl-coenzyme A oxidase; Region: PLN02526
755732001008	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
755732001009	active site
755732001010	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
755732001011	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
755732001012	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732001013	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
755732001014	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
755732001015	generic binding surface II; other site
755732001016	ssDNA binding site; other site
755732001017	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732001018	ATP binding site [chemical binding]; other site
755732001019	putative Mg++ binding site [ion binding]; other site
755732001020	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732001021	nucleotide binding region [chemical binding]; other site
755732001022	ATP-binding site [chemical binding]; other site
755732001023	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
755732001024	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
755732001025	FMN binding site [chemical binding]; other site
755732001026	active site
755732001027	catalytic residues [active]
755732001028	substrate binding site [chemical binding]; other site
755732001029	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
755732001030	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
755732001031	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732001032	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
755732001033	active site
755732001034	C-terminal peptidase (prc); Region: prc; TIGR00225
755732001035	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
755732001036	Catalytic dyad [active]
755732001037	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cl00540
755732001038	tetramerization interface [polypeptide binding]; other site
755732001039	active site
755732001040	UbiA prenyltransferase family; Region: UbiA; pfam01040
755732001041	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
755732001042	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
755732001043	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
755732001044	CoA-ligase; Region: Ligase_CoA; pfam00549
755732001045	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
755732001046	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
755732001047	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
755732001048	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
755732001049	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
755732001050	Family of unknown function (DUF490); Region: DUF490; pfam04357
755732001051	UGMP family protein; Validated; Region: PRK09604
755732001052	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
755732001053	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
755732001054	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
755732001055	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
755732001056	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
755732001057	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732001058	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732001059	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732001060	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732001061	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732001062	glutamate dehydrogenase; Provisional; Region: PRK09414
755732001063	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
755732001064	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
755732001065	NAD(P) binding site [chemical binding]; other site
755732001066	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
755732001067	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
755732001068	TPP-binding site [chemical binding]; other site
755732001069	tetramer interface [polypeptide binding]; other site
755732001070	heterodimer interface [polypeptide binding]; other site
755732001071	phosphorylation loop region [posttranslational modification]
755732001072	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
755732001073	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
755732001074	alpha subunit interface [polypeptide binding]; other site
755732001075	TPP binding site [chemical binding]; other site
755732001076	heterodimer interface [polypeptide binding]; other site
755732001077	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
755732001078	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
755732001079	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
755732001080	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
755732001081	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
755732001082	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
755732001083	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
755732001084	Protein of unknown function (Porph_ging); Region: Porph_ging; cl09903
755732001085	Arginase family; Region: Arginase; cd09989
755732001086	active site
755732001087	Mn binding site [ion binding]; other site
755732001088	oligomer interface [polypeptide binding]; other site
755732001089	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
755732001090	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
755732001091	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732001092	active site
755732001093	HIGH motif; other site
755732001094	nucleotide binding site [chemical binding]; other site
755732001095	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
755732001096	KMSK motif region; other site
755732001097	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
755732001098	tRNA binding surface [nucleotide binding]; other site
755732001099	anticodon binding site; other site
755732001100	Predicted membrane protein [Function unknown]; Region: COG2261
755732001101	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
755732001102	RNA methyltransferase, RsmE family; Region: TIGR00046
755732001103	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
755732001104	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
755732001105	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
755732001106	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
755732001107	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
755732001108	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
755732001109	G1 box; other site
755732001110	putative GEF interaction site [polypeptide binding]; other site
755732001111	GTP/Mg2+ binding site [chemical binding]; other site
755732001112	Switch I region; other site
755732001113	G2 box; other site
755732001114	G3 box; other site
755732001115	Switch II region; other site
755732001116	G4 box; other site
755732001117	G5 box; other site
755732001118	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
755732001119	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732001120	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
755732001121	ligand binding site [chemical binding]; other site
755732001122	active site
755732001123	UGI interface [polypeptide binding]; other site
755732001124	catalytic site [active]
755732001125	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
755732001126	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
755732001127	substrate binding site [chemical binding]; other site
755732001128	active site
755732001129	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732001130	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732001131	ligand binding site [chemical binding]; other site
755732001132	esterase, PHB depolymerase family; Region: esterase_phb; TIGR01840
755732001133	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732001135	putative substrate translocation pore; other site
755732001136	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
755732001137	Hint module; Region: Hint; pfam01079
755732001138	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001139	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
755732001140	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001141	active site
755732001142	phosphorylation site [posttranslational modification]
755732001143	intermolecular recognition site; other site
755732001144	dimerization interface [polypeptide binding]; other site
755732001145	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732001146	Walker A motif; other site
755732001147	ATP binding site [chemical binding]; other site
755732001148	Walker B motif; other site
755732001149	arginine finger; other site
755732001150	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
755732001151	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
755732001152	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
755732001153	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
755732001154	Soluble P-type ATPase [General function prediction only]; Region: COG4087
755732001155	K+-transporting ATPase, c chain; Region: KdpC; cl00944
755732001156	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
755732001157	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
755732001158	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
755732001159	Ligand Binding Site [chemical binding]; other site
755732001160	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
755732001161	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
755732001162	dimerization interface [polypeptide binding]; other site
755732001163	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
755732001164	putative active site [active]
755732001165	heme pocket [chemical binding]; other site
755732001166	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732001167	dimer interface [polypeptide binding]; other site
755732001168	phosphorylation site [posttranslational modification]
755732001169	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732001170	ATP binding site [chemical binding]; other site
755732001171	Mg2+ binding site [ion binding]; other site
755732001172	G-X-G motif; other site
755732001173	K+ potassium transporter; Region: K_trans; pfam02705
755732001174	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732001175	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001176	active site
755732001177	phosphorylation site [posttranslational modification]
755732001178	intermolecular recognition site; other site
755732001179	dimerization interface [polypeptide binding]; other site
755732001180	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732001181	DNA binding site [nucleotide binding]
755732001182	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
755732001183	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
755732001184	Prokaryotic RING finger family 4; Region: Prok-RING_4; pfam14447
755732001185	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
755732001186	putative metal binding site [ion binding]; other site
755732001187	Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417
755732001188	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
755732001189	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
755732001190	WYL domain; Region: WYL; pfam13280
755732001191	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
755732001192	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
755732001193	Transposase; Region: DDE_Tnp_ISL3; pfam01610
755732001194	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732001195	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732001196	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001197	active site
755732001198	phosphorylation site [posttranslational modification]
755732001199	intermolecular recognition site; other site
755732001200	dimerization interface [polypeptide binding]; other site
755732001201	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732001202	DNA binding residues [nucleotide binding]
755732001203	dimerization interface [polypeptide binding]; other site
755732001204	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
755732001205	Walker A motif; other site
755732001206	ATP binding site [chemical binding]; other site
755732001207	Walker B motif; other site
755732001208	arginine finger; other site
755732001209	N-acetylmuramoyl-L-alanine amidase; Region: Amidase_2; pfam01510
755732001210	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732001211	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
755732001212	Transposase; Region: DDE_Tnp_ISL3; pfam01610
755732001213	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
755732001214	Abi-like protein; Region: Abi_2; pfam07751
755732001215	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732001216	non-specific DNA binding site [nucleotide binding]; other site
755732001217	salt bridge; other site
755732001218	sequence-specific DNA binding site [nucleotide binding]; other site
755732001219	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
755732001220	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
755732001221	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
755732001222	Methyltransferase domain; Region: Methyltransf_26; pfam13659
755732001223	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732001224	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732001225	non-specific DNA binding site [nucleotide binding]; other site
755732001226	salt bridge; other site
755732001227	sequence-specific DNA binding site [nucleotide binding]; other site
755732001228	VirE N-terminal domain; Region: VirE_N; pfam08800
755732001229	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
755732001230	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732001231	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
755732001232	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
755732001233	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
755732001234	Int/Topo IB signature motif; other site
755732001235	Pirin; Region: Pirin; pfam02678
755732001236	Pirin-related protein [General function prediction only]; Region: COG1741
755732001237	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
755732001238	dimer interface [polypeptide binding]; other site
755732001239	FMN binding site [chemical binding]; other site
755732001240	Uncharacterized conserved protein [Function unknown]; Region: COG2353
755732001241	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001242	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001243	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732001244	Family description; Region: VCBS; pfam13517
755732001245	Family description; Region: VCBS; pfam13517
755732001246	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001247	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
755732001248	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
755732001249	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
755732001250	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
755732001251	Uncharacterized conserved protein [Function unknown]; Region: COG2353
755732001252	Reeler, the N-terminal domain of reelin, F-spondin, and a variety of other proteins; Region: Reeler; cd08544
755732001253	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001254	methionine sulfoxide reductase B; Provisional; Region: PRK05508
755732001255	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
755732001256	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
755732001257	N-acetyl-D-glucosamine binding site [chemical binding]; other site
755732001258	catalytic residue [active]
755732001259	Haemolytic domain; Region: Haemolytic; pfam01809
755732001260	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001261	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
755732001262	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732001263	active site
755732001264	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732001265	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001266	aspartate aminotransferase; Provisional; Region: PRK05764
755732001267	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
755732001268	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732001269	homodimer interface [polypeptide binding]; other site
755732001270	catalytic residue [active]
755732001271	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
755732001272	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001273	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732001274	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732001275	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
755732001276	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732001277	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
755732001278	protein binding site [polypeptide binding]; other site
755732001279	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
755732001280	Domain interface; other site
755732001281	Peptide binding site; other site
755732001282	Active site tetrad [active]
755732001283	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
755732001284	dimer interface [polypeptide binding]; other site
755732001285	putative tRNA-binding site [nucleotide binding]; other site
755732001286	DinB superfamily; Region: DinB_2; pfam12867
755732001287	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732001288	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
755732001289	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
755732001290	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
755732001291	Probable Catalytic site; other site
755732001292	metal-binding site
755732001293	SdiA-regulated; Region: SdiA-regulated; cd09971
755732001294	putative active site [active]
755732001295	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
755732001296	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
755732001297	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732001298	S-adenosylmethionine binding site [chemical binding]; other site
755732001299	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
755732001300	Dehydroquinase class II; Region: DHquinase_II; pfam01220
755732001301	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
755732001302	active site
755732001303	trimer interface [polypeptide binding]; other site
755732001304	dimer interface [polypeptide binding]; other site
755732001305	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
755732001306	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
755732001307	active site
755732001308	Int/Topo IB signature motif; other site
755732001309	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
755732001310	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
755732001311	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732001312	FeS/SAM binding site; other site
755732001313	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
755732001314	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
755732001315	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
755732001316	active site residue [active]
755732001317	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
755732001318	four helix bundle protein; Region: TIGR02436
755732001319	replicative DNA helicase; Region: DnaB; TIGR00665
755732001320	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
755732001321	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
755732001322	Walker A motif; other site
755732001323	ATP binding site [chemical binding]; other site
755732001324	Walker B motif; other site
755732001325	DNA binding loops [nucleotide binding]
755732001326	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732001327	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
755732001328	active site
755732001329	putative catalytic site [active]
755732001330	DNA binding site [nucleotide binding]
755732001331	putative phosphate binding site [ion binding]; other site
755732001332	metal binding site A [ion binding]; metal-binding site
755732001333	AP binding site [nucleotide binding]; other site
755732001334	metal binding site B [ion binding]; metal-binding site
755732001335	MutS domain III; Region: MutS_III; pfam05192
755732001336	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732001337	Walker A/P-loop; other site
755732001338	ATP binding site [chemical binding]; other site
755732001339	Q-loop/lid; other site
755732001340	ABC transporter signature motif; other site
755732001341	Walker B; other site
755732001342	D-loop; other site
755732001343	H-loop/switch region; other site
755732001344	POT family; Region: PTR2; cl17359
755732001345	Protein of unknown function, DUF481; Region: DUF481; cl01213
755732001346	Predicted permeases [General function prediction only]; Region: COG0795
755732001347	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
755732001348	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
755732001349	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
755732001350	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
755732001351	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
755732001352	active site
755732001353	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
755732001354	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732001355	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
755732001356	DNA binding residues [nucleotide binding]
755732001357	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
755732001358	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
755732001359	acyl-activating enzyme (AAE) consensus motif; other site
755732001360	putative AMP binding site [chemical binding]; other site
755732001361	putative active site [active]
755732001362	putative CoA binding site [chemical binding]; other site
755732001363	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
755732001364	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
755732001365	active site
755732001366	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
755732001367	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732001368	NAD(P) binding site [chemical binding]; other site
755732001369	active site
755732001370	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
755732001371	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
755732001372	dimerization interface [polypeptide binding]; other site
755732001373	ATP binding site [chemical binding]; other site
755732001374	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
755732001375	dimerization interface [polypeptide binding]; other site
755732001376	ATP binding site [chemical binding]; other site
755732001377	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
755732001378	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732001379	S-adenosylmethionine binding site [chemical binding]; other site
755732001380	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
755732001381	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
755732001382	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
755732001383	Homeodomain-like domain; Region: HTH_23; pfam13384
755732001384	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732001385	putative substrate translocation pore; other site
755732001386	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732001387	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732001388	non-specific DNA binding site [nucleotide binding]; other site
755732001389	salt bridge; other site
755732001390	sequence-specific DNA binding site [nucleotide binding]; other site
755732001391	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
755732001392	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
755732001393	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
755732001394	acetyl-CoA synthetase; Provisional; Region: PRK00174
755732001395	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
755732001396	active site
755732001397	CoA binding site [chemical binding]; other site
755732001398	acyl-activating enzyme (AAE) consensus motif; other site
755732001399	AMP binding site [chemical binding]; other site
755732001400	acetate binding site [chemical binding]; other site
755732001401	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
755732001402	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001403	active site
755732001404	phosphorylation site [posttranslational modification]
755732001405	intermolecular recognition site; other site
755732001406	dimerization interface [polypeptide binding]; other site
755732001407	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
755732001408	Na binding site [ion binding]; other site
755732001409	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732001410	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732001411	dimer interface [polypeptide binding]; other site
755732001412	phosphorylation site [posttranslational modification]
755732001413	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732001414	ATP binding site [chemical binding]; other site
755732001415	Mg2+ binding site [ion binding]; other site
755732001416	G-X-G motif; other site
755732001417	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732001418	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732001419	binding surface
755732001420	TPR repeat; Region: TPR_11; pfam13414
755732001421	TPR motif; other site
755732001422	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
755732001423	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
755732001424	active site
755732001425	catalytic triad [active]
755732001426	oxyanion hole [active]
755732001427	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732001428	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
755732001429	active site
755732001430	catalytic triad [active]
755732001431	oxyanion hole [active]
755732001432	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
755732001433	nucleotide binding site/active site [active]
755732001434	HIT family signature motif; other site
755732001435	catalytic residue [active]
755732001436	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
755732001437	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
755732001438	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
755732001439	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001440	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001441	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732001442	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732001443	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
755732001444	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
755732001445	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
755732001446	geranylgeranylglyceryl phosphate synthase-like protein; Reviewed; Region: PRK04169
755732001447	phosphate binding site [ion binding]; other site
755732001448	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732001449	active site
755732001450	PKD domain; Region: PKD; pfam00801
755732001451	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
755732001452	DEAD-like helicases superfamily; Region: DEXDc; smart00487
755732001453	putative Mg++ binding site [ion binding]; other site
755732001454	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
755732001455	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
755732001456	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
755732001457	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732001458	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
755732001459	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
755732001460	dimerization interface [polypeptide binding]; other site
755732001461	active site
755732001462	Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472
755732001463	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
755732001464	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
755732001465	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
755732001466	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732001467	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732001468	NAD(P) binding site [chemical binding]; other site
755732001469	active site
755732001470	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
755732001471	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
755732001472	inhibitor-cofactor binding pocket; inhibition site
755732001473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732001474	catalytic residue [active]
755732001475	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
755732001476	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
755732001477	putative trimer interface [polypeptide binding]; other site
755732001478	putative CoA binding site [chemical binding]; other site
755732001479	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
755732001480	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732001481	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732001482	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
755732001483	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732001484	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
755732001485	active site
755732001486	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
755732001487	dimer interface [polypeptide binding]; other site
755732001488	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
755732001489	Ligand Binding Site [chemical binding]; other site
755732001490	Molecular Tunnel; other site
755732001491	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732001492	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732001493	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
755732001494	active site
755732001495	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
755732001496	homodimer interface [polypeptide binding]; other site
755732001497	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732001498	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
755732001499	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
755732001500	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
755732001501	active site
755732001502	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
755732001503	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
755732001504	Ligand Binding Site [chemical binding]; other site
755732001505	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732001506	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732001507	NAD(P) binding site [chemical binding]; other site
755732001508	active site
755732001509	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732001510	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732001511	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732001512	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732001513	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
755732001514	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
755732001515	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
755732001516	active site
755732001517	dimer interface [polypeptide binding]; other site
755732001518	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
755732001519	Ligand Binding Site [chemical binding]; other site
755732001520	Molecular Tunnel; other site
755732001521	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
755732001522	putative hydrophobic ligand binding site [chemical binding]; other site
755732001523	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
755732001524	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
755732001525	dimer interface [polypeptide binding]; other site
755732001526	short chain dehydrogenase; Validated; Region: PRK06182
755732001527	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
755732001528	NADP binding site [chemical binding]; other site
755732001529	active site
755732001530	steroid binding site; other site
755732001531	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
755732001532	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
755732001533	active site
755732001534	dimerization interface [polypeptide binding]; other site
755732001535	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
755732001536	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
755732001537	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
755732001538	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
755732001539	urocanate hydratase; Provisional; Region: PRK05414
755732001540	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
755732001541	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732001542	enolase; Provisional; Region: eno; PRK00077
755732001543	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
755732001544	dimer interface [polypeptide binding]; other site
755732001545	metal binding site [ion binding]; metal-binding site
755732001546	substrate binding pocket [chemical binding]; other site
755732001547	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
755732001548	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
755732001549	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
755732001550	catalytic site [active]
755732001551	subunit interface [polypeptide binding]; other site
755732001552	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
755732001553	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
755732001554	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
755732001555	alphaNTD homodimer interface [polypeptide binding]; other site
755732001556	alphaNTD - beta interaction site [polypeptide binding]; other site
755732001557	alphaNTD - beta' interaction site [polypeptide binding]; other site
755732001558	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
755732001559	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
755732001560	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
755732001561	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
755732001562	RNA binding surface [nucleotide binding]; other site
755732001563	30S ribosomal protein S11; Validated; Region: PRK05309
755732001564	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
755732001565	30S ribosomal protein S13; Region: bact_S13; TIGR03631
755732001566	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
755732001567	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
755732001568	rRNA binding site [nucleotide binding]; other site
755732001569	predicted 30S ribosome binding site; other site
755732001570	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
755732001571	SecY translocase; Region: SecY; pfam00344
755732001572	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
755732001573	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
755732001574	23S rRNA binding site [nucleotide binding]; other site
755732001575	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
755732001576	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
755732001577	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
755732001578	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
755732001579	5S rRNA interface [nucleotide binding]; other site
755732001580	L27 interface [polypeptide binding]; other site
755732001581	23S rRNA interface [nucleotide binding]; other site
755732001582	L5 interface [polypeptide binding]; other site
755732001583	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
755732001584	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
755732001585	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
755732001586	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
755732001587	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
755732001588	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
755732001589	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
755732001590	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
755732001591	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
755732001592	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
755732001593	RNA binding site [nucleotide binding]; other site
755732001594	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
755732001595	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
755732001596	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
755732001597	23S rRNA interface [nucleotide binding]; other site
755732001598	putative translocon interaction site; other site
755732001599	signal recognition particle (SRP54) interaction site; other site
755732001600	L23 interface [polypeptide binding]; other site
755732001601	trigger factor interaction site; other site
755732001602	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
755732001603	23S rRNA interface [nucleotide binding]; other site
755732001604	5S rRNA interface [nucleotide binding]; other site
755732001605	putative antibiotic binding site [chemical binding]; other site
755732001606	L25 interface [polypeptide binding]; other site
755732001607	L27 interface [polypeptide binding]; other site
755732001608	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
755732001609	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
755732001610	G-X-X-G motif; other site
755732001611	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
755732001612	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
755732001613	putative translocon binding site; other site
755732001614	protein-rRNA interface [nucleotide binding]; other site
755732001615	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
755732001616	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
755732001617	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
755732001618	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
755732001619	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
755732001620	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
755732001621	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
755732001622	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
755732001623	elongation factor G; Reviewed; Region: PRK12739
755732001624	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
755732001625	G1 box; other site
755732001626	putative GEF interaction site [polypeptide binding]; other site
755732001627	GTP/Mg2+ binding site [chemical binding]; other site
755732001628	Switch I region; other site
755732001629	G2 box; other site
755732001630	G3 box; other site
755732001631	Switch II region; other site
755732001632	G4 box; other site
755732001633	G5 box; other site
755732001634	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
755732001635	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
755732001636	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
755732001637	30S ribosomal protein S7; Validated; Region: PRK05302
755732001638	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
755732001639	S17 interaction site [polypeptide binding]; other site
755732001640	S8 interaction site; other site
755732001641	16S rRNA interaction site [nucleotide binding]; other site
755732001642	streptomycin interaction site [chemical binding]; other site
755732001643	23S rRNA interaction site [nucleotide binding]; other site
755732001644	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
755732001645	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
755732001646	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001647	Family description; Region: VCBS; pfam13517
755732001648	Family description; Region: VCBS; pfam13517
755732001649	Family description; Region: VCBS; pfam13517
755732001650	Family description; Region: VCBS; pfam13517
755732001651	Family description; Region: VCBS; pfam13517
755732001652	Family description; Region: VCBS; pfam13517
755732001653	Family description; Region: VCBS; pfam13517
755732001654	Family description; Region: VCBS; pfam13517
755732001655	Family description; Region: VCBS; pfam13517
755732001656	Family description; Region: VCBS; pfam13517
755732001657	Lamin Tail Domain; Region: LTD; pfam00932
755732001658	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001659	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
755732001660	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
755732001661	dimer interface [polypeptide binding]; other site
755732001662	active site
755732001663	CoA binding pocket [chemical binding]; other site
755732001664	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001665	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
755732001666	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
755732001667	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
755732001668	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
755732001669	Switch II region; other site
755732001670	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
755732001671	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
755732001672	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
755732001673	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
755732001674	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
755732001675	FMN binding site [chemical binding]; other site
755732001676	active site
755732001677	substrate binding site [chemical binding]; other site
755732001678	catalytic residue [active]
755732001679	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
755732001680	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
755732001681	putative NAD(P) binding site [chemical binding]; other site
755732001682	dimer interface [polypeptide binding]; other site
755732001683	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
755732001684	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
755732001685	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
755732001686	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
755732001687	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732001688	Predicted membrane protein [Function unknown]; Region: COG4267
755732001689	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732001690	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
755732001691	Part of AAA domain; Region: AAA_19; pfam13245
755732001692	Family description; Region: UvrD_C_2; pfam13538
755732001693	GLPGLI family protein; Region: GLPGLI; TIGR01200
755732001694	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732001695	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
755732001696	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
755732001697	dimer interface [polypeptide binding]; other site
755732001698	ssDNA binding site [nucleotide binding]; other site
755732001699	tetramer (dimer of dimers) interface [polypeptide binding]; other site
755732001700	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
755732001701	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
755732001702	dimer interface [polypeptide binding]; other site
755732001703	ssDNA binding site [nucleotide binding]; other site
755732001704	tetramer (dimer of dimers) interface [polypeptide binding]; other site
755732001705	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
755732001706	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
755732001707	dimer interface [polypeptide binding]; other site
755732001708	ssDNA binding site [nucleotide binding]; other site
755732001709	tetramer (dimer of dimers) interface [polypeptide binding]; other site
755732001710	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
755732001711	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
755732001712	Domain of unknown function (DUF4304); Region: DUF4304; pfam14137
755732001713	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
755732001714	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
755732001715	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
755732001716	NAD binding site [chemical binding]; other site
755732001717	active site
755732001718	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732001719	Histidine kinase; Region: His_kinase; pfam06580
755732001720	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732001721	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732001722	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001723	active site
755732001724	phosphorylation site [posttranslational modification]
755732001725	intermolecular recognition site; other site
755732001726	dimerization interface [polypeptide binding]; other site
755732001727	LytTr DNA-binding domain; Region: LytTR; smart00850
755732001728	DNA topoisomerase III; Provisional; Region: PRK07726
755732001729	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
755732001730	active site
755732001731	putative interdomain interaction site [polypeptide binding]; other site
755732001732	putative metal-binding site [ion binding]; other site
755732001733	putative nucleotide binding site [chemical binding]; other site
755732001734	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
755732001735	domain I; other site
755732001736	DNA binding groove [nucleotide binding]
755732001737	phosphate binding site [ion binding]; other site
755732001738	domain II; other site
755732001739	domain III; other site
755732001740	nucleotide binding site [chemical binding]; other site
755732001741	catalytic site [active]
755732001742	domain IV; other site
755732001743	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
755732001744	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
755732001745	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
755732001746	folate binding site [chemical binding]; other site
755732001747	NADP+ binding site [chemical binding]; other site
755732001748	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
755732001749	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
755732001750	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
755732001751	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
755732001752	metal binding site [ion binding]; metal-binding site
755732001753	dimer interface [polypeptide binding]; other site
755732001754	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
755732001755	catalytic site [active]
755732001756	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732001757	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732001758	dimer interface [polypeptide binding]; other site
755732001759	phosphorylation site [posttranslational modification]
755732001760	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732001761	ATP binding site [chemical binding]; other site
755732001762	Mg2+ binding site [ion binding]; other site
755732001763	G-X-G motif; other site
755732001764	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
755732001765	active site residue [active]
755732001766	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
755732001767	ATP-GRASP peptide maturase, grasp-with-spasm system; Region: GRASP_w_spasm; TIGR04192
755732001768	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
755732001769	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
755732001770	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
755732001771	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
755732001772	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
755732001773	MutS domain I; Region: MutS_I; pfam01624
755732001774	MutS domain II; Region: MutS_II; pfam05188
755732001775	MutS domain III; Region: MutS_III; pfam05192
755732001776	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
755732001777	Walker A/P-loop; other site
755732001778	ATP binding site [chemical binding]; other site
755732001779	Q-loop/lid; other site
755732001780	ABC transporter signature motif; other site
755732001781	Walker B; other site
755732001782	D-loop; other site
755732001783	H-loop/switch region; other site
755732001784	Fatty acid desaturase; Region: FA_desaturase; pfam00487
755732001785	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
755732001786	putative di-iron ligands [ion binding]; other site
755732001787	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732001788	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001789	active site
755732001790	phosphorylation site [posttranslational modification]
755732001791	intermolecular recognition site; other site
755732001792	dimerization interface [polypeptide binding]; other site
755732001793	LytTr DNA-binding domain; Region: LytTR; pfam04397
755732001794	Histidine kinase; Region: His_kinase; pfam06580
755732001795	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732001796	ATP binding site [chemical binding]; other site
755732001797	Mg2+ binding site [ion binding]; other site
755732001798	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732001799	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
755732001800	Histidine kinase; Region: His_kinase; pfam06580
755732001801	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732001802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001803	active site
755732001804	phosphorylation site [posttranslational modification]
755732001805	intermolecular recognition site; other site
755732001806	dimerization interface [polypeptide binding]; other site
755732001807	LytTr DNA-binding domain; Region: LytTR; smart00850
755732001808	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
755732001809	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
755732001810	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
755732001811	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
755732001812	alpha subunit interface [polypeptide binding]; other site
755732001813	TPP binding site [chemical binding]; other site
755732001814	heterodimer interface [polypeptide binding]; other site
755732001815	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
755732001816	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
755732001817	Ligand binding site [chemical binding]; other site
755732001818	Electron transfer flavoprotein domain; Region: ETF; pfam01012
755732001819	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
755732001820	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
755732001821	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
755732001822	Bifunctional nuclease; Region: DNase-RNase; pfam02577
755732001823	UvrB/uvrC motif; Region: UVR; pfam02151
755732001824	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
755732001825	CotH protein; Region: CotH; pfam08757
755732001826	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732001827	thymidylate synthase; Reviewed; Region: thyA; PRK01827
755732001828	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
755732001829	dimerization interface [polypeptide binding]; other site
755732001830	active site
755732001831	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
755732001832	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732001833	ATP binding site [chemical binding]; other site
755732001834	putative Mg++ binding site [ion binding]; other site
755732001835	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732001836	nucleotide binding region [chemical binding]; other site
755732001837	ATP-binding site [chemical binding]; other site
755732001838	RQC domain; Region: RQC; pfam09382
755732001839	HRDC domain; Region: HRDC; pfam00570
755732001840	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
755732001841	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732001842	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
755732001843	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
755732001844	Walker A/P-loop; other site
755732001845	ATP binding site [chemical binding]; other site
755732001846	Q-loop/lid; other site
755732001847	ABC transporter signature motif; other site
755732001848	Walker B; other site
755732001849	D-loop; other site
755732001850	H-loop/switch region; other site
755732001851	Surface antigen; Region: Bac_surface_Ag; pfam01103
755732001852	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732001853	AAA domain; Region: AAA_30; pfam13604
755732001854	Family description; Region: UvrD_C_2; pfam13538
755732001855	von Willebrand factor type A domain; Region: VWA_2; pfam13519
755732001856	S-adenosylmethionine synthetase; Validated; Region: PRK05250
755732001857	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
755732001858	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
755732001859	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
755732001860	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
755732001861	Histidine kinase; Region: His_kinase; pfam06580
755732001862	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732001863	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001864	active site
755732001865	phosphorylation site [posttranslational modification]
755732001866	intermolecular recognition site; other site
755732001867	dimerization interface [polypeptide binding]; other site
755732001868	LytTr DNA-binding domain; Region: LytTR; smart00850
755732001869	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
755732001870	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
755732001871	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
755732001872	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
755732001873	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
755732001874	Protein of unknown function (DUF419); Region: DUF419; pfam04237
755732001875	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
755732001876	metal-binding site [ion binding]
755732001877	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732001878	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732001879	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732001880	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
755732001881	metal binding site 2 [ion binding]; metal-binding site
755732001882	putative DNA binding helix; other site
755732001883	metal binding site 1 [ion binding]; metal-binding site
755732001884	dimer interface [polypeptide binding]; other site
755732001885	structural Zn2+ binding site [ion binding]; other site
755732001886	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
755732001887	Cation efflux family; Region: Cation_efflux; pfam01545
755732001888	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
755732001889	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
755732001890	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732001891	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
755732001892	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
755732001893	Substrate binding site; other site
755732001894	SprT-like family; Region: SprT-like; pfam10263
755732001895	SprT homologues; Region: SprT; cl01182
755732001896	Permease; Region: Permease; pfam02405
755732001897	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
755732001898	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
755732001899	Walker A/P-loop; other site
755732001900	ATP binding site [chemical binding]; other site
755732001901	Q-loop/lid; other site
755732001902	ABC transporter signature motif; other site
755732001903	Walker B; other site
755732001904	D-loop; other site
755732001905	H-loop/switch region; other site
755732001906	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
755732001907	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
755732001908	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
755732001909	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
755732001910	Histidine kinase; Region: His_kinase; pfam06580
755732001911	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732001912	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732001913	active site
755732001914	phosphorylation site [posttranslational modification]
755732001915	intermolecular recognition site; other site
755732001916	dimerization interface [polypeptide binding]; other site
755732001917	LytTr DNA-binding domain; Region: LytTR; smart00850
755732001918	Tandem repeat subunit of reelin and related proteins; Region: Reelin_subrepeat_like; cl15240
755732001919	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732001920	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732001921	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732001922	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732001923	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
755732001924	active site
755732001925	nucleotide binding site [chemical binding]; other site
755732001926	HIGH motif; other site
755732001927	KMSKS motif; other site
755732001928	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
755732001929	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
755732001930	tetramerization interface [polypeptide binding]; other site
755732001931	active site
755732001932	pantoate--beta-alanine ligase; Region: panC; TIGR00018
755732001933	Pantoate-beta-alanine ligase; Region: PanC; cd00560
755732001934	active site
755732001935	ATP-binding site [chemical binding]; other site
755732001936	pantoate-binding site; other site
755732001937	HXXH motif; other site
755732001938	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
755732001939	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
755732001940	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
755732001941	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
755732001942	glutaminase active site [active]
755732001943	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
755732001944	dimer interface [polypeptide binding]; other site
755732001945	active site
755732001946	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
755732001947	dimer interface [polypeptide binding]; other site
755732001948	active site
755732001949	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
755732001950	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732001951	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
755732001952	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
755732001953	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
755732001954	substrate binding site; other site
755732001955	tetramer interface; other site
755732001956	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
755732001957	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
755732001958	substrate binding pocket [chemical binding]; other site
755732001959	chain length determination region; other site
755732001960	substrate-Mg2+ binding site; other site
755732001961	catalytic residues [active]
755732001962	aspartate-rich region 1; other site
755732001963	active site lid residues [active]
755732001964	aspartate-rich region 2; other site
755732001965	lycopene cyclase domain; Region: CarR_dom_SF; TIGR03462
755732001966	lycopene cyclase domain; Region: CarR_dom_SF; TIGR03462
755732001967	beta-carotene hydroxylase; Region: PLN02601
755732001968	Protein of unknown function (DUF422); Region: DUF422; cl00991
755732001969	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732001970	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732001971	TPR motif; other site
755732001972	binding surface
755732001973	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732001974	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732001975	binding surface
755732001976	TPR motif; other site
755732001977	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732001978	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732001979	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
755732001980	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
755732001981	HflX GTPase family; Region: HflX; cd01878
755732001982	G1 box; other site
755732001983	GTP/Mg2+ binding site [chemical binding]; other site
755732001984	Switch I region; other site
755732001985	G2 box; other site
755732001986	G3 box; other site
755732001987	Switch II region; other site
755732001988	G4 box; other site
755732001989	G5 box; other site
755732001990	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
755732001991	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
755732001992	active site
755732001993	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
755732001994	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
755732001995	active site
755732001996	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
755732001997	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
755732001998	Amidohydrolase; Region: Amidohydro_4; pfam13147
755732001999	active site
755732002000	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002001	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
755732002002	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
755732002003	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
755732002004	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732002005	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002006	NifU-like domain; Region: NifU; cl00484
755732002007	Domain of unknown function DUF59; Region: DUF59; pfam01883
755732002008	septum site-determining protein MinD; Region: minD_bact; TIGR01968
755732002009	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
755732002010	Walker A motif; other site
755732002011	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732002012	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
755732002013	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732002014	ligand binding site [chemical binding]; other site
755732002015	CoA binding domain; Region: CoA_binding_2; pfam13380
755732002016	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
755732002017	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
755732002018	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
755732002019	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
755732002020	RNA binding site [nucleotide binding]; other site
755732002021	active site
755732002022	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
755732002023	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
755732002024	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
755732002025	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
755732002026	YceI-like domain; Region: YceI; pfam04264
755732002027	Pyrococcus aspartate kinase subunit, putative; Region: AspKin_pair; TIGR02078
755732002028	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
755732002029	nucleotide binding site [chemical binding]; other site
755732002030	substrate binding site [chemical binding]; other site
755732002031	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732002032	ligand binding site [chemical binding]; other site
755732002033	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732002034	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732002035	ligand binding site [chemical binding]; other site
755732002036	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
755732002037	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
755732002038	DNA binding residues [nucleotide binding]
755732002039	B12 binding domain; Region: B12-binding_2; pfam02607
755732002040	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
755732002041	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732002042	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732002043	DNA binding residues [nucleotide binding]
755732002044	phytoene desaturase; Region: crtI_fam; TIGR02734
755732002045	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732002046	RAB proteins geranylgeranyltransferase component A (RAB escort protein) [Posttranslational modification, protein turnover, chaperones]; Region: MRS6; cl17678
755732002047	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
755732002048	active site lid residues [active]
755732002049	substrate binding pocket [chemical binding]; other site
755732002050	catalytic residues [active]
755732002051	substrate-Mg2+ binding site; other site
755732002052	aspartate-rich region 1; other site
755732002053	aspartate-rich region 2; other site
755732002054	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
755732002055	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
755732002056	active site
755732002057	metal binding site [ion binding]; metal-binding site
755732002058	nudix motif; other site
755732002059	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
755732002060	active site
755732002061	DNA photolyase; Region: DNA_photolyase; pfam00875
755732002062	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
755732002063	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732002064	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
755732002065	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
755732002066	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
755732002067	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
755732002068	active site
755732002069	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
755732002070	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
755732002071	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
755732002072	SurA N-terminal domain; Region: SurA_N; pfam09312
755732002073	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
755732002074	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
755732002075	MoxR-like ATPases [General function prediction only]; Region: COG0714
755732002076	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732002077	Walker A motif; other site
755732002078	ATP binding site [chemical binding]; other site
755732002079	Walker B motif; other site
755732002080	arginine finger; other site
755732002081	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
755732002082	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
755732002083	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732002084	phosphatidylinositol phosphate kinase; Provisional; Region: PLN03185
755732002085	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732002086	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
755732002087	hypothetical protein; Provisional; Region: PRK07236
755732002088	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
755732002089	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
755732002090	heme-binding site [chemical binding]; other site
755732002091	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
755732002092	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
755732002093	active site
755732002094	catalytic site [active]
755732002095	substrate binding site [chemical binding]; other site
755732002096	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
755732002097	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
755732002098	active site
755732002099	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
755732002100	generic binding surface II; other site
755732002101	generic binding surface I; other site
755732002102	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
755732002103	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
755732002104	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
755732002105	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
755732002106	active site
755732002107	catalytic residues [active]
755732002108	metal binding site [ion binding]; metal-binding site
755732002109	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
755732002110	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
755732002111	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
755732002112	trimer interface [polypeptide binding]; other site
755732002113	active site
755732002114	substrate binding site [chemical binding]; other site
755732002115	CoA binding site [chemical binding]; other site
755732002116	Protein of unknown function DUF262; Region: DUF262; pfam03235
755732002117	Uncharacterized conserved protein [Function unknown]; Region: COG1479
755732002118	aconitate hydratase, mitochondrial; Region: aconitase_mito; TIGR01340
755732002119	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Mitochondrial; cd01584
755732002120	substrate binding site [chemical binding]; other site
755732002121	ligand binding site [chemical binding]; other site
755732002122	Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes...; Region: AcnA_Mitochon_Swivel; cd01578
755732002123	substrate binding site [chemical binding]; other site
755732002124	YcfA-like protein; Region: YcfA; cl00752
755732002125	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
755732002126	Aconitate hydratase 2 N-terminus; Region: Aconitase_2_N; pfam06434
755732002127	substrate binding site [chemical binding]; other site
755732002128	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
755732002129	substrate binding site [chemical binding]; other site
755732002130	ligand binding site [chemical binding]; other site
755732002131	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002132	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732002133	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732002134	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002135	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732002136	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002137	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732002138	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002139	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732002140	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002141	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732002142	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002143	active site
755732002144	phosphorylation site [posttranslational modification]
755732002145	intermolecular recognition site; other site
755732002146	dimerization interface [polypeptide binding]; other site
755732002147	LytTr DNA-binding domain; Region: LytTR; smart00850
755732002148	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732002149	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002150	binding surface
755732002151	TPR motif; other site
755732002152	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002153	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002154	Histidine kinase; Region: His_kinase; pfam06580
755732002155	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732002156	ATP binding site [chemical binding]; other site
755732002157	Mg2+ binding site [ion binding]; other site
755732002158	G-X-G motif; other site
755732002159	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002160	Family of unknown function (DUF3836); Region: DUF3836; pfam12930
755732002161	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002162	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
755732002163	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
755732002164	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
755732002165	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
755732002166	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
755732002167	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
755732002168	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
755732002169	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732002170	catalytic triad [active]
755732002171	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
755732002172	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
755732002173	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
755732002174	LytTr DNA-binding domain; Region: LytTR; smart00850
755732002175	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
755732002176	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
755732002177	ATP-GRASP peptide maturase, grasp-with-spasm system; Region: GRASP_w_spasm; TIGR04192
755732002178	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732002179	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732002180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002181	active site
755732002182	phosphorylation site [posttranslational modification]
755732002183	LytTr DNA-binding domain; Region: LytTR; smart00850
755732002184	Histidine kinase; Region: His_kinase; pfam06580
755732002185	CAAX protease self-immunity; Region: Abi; pfam02517
755732002186	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
755732002187	Protein of unknown function (DUF1043); Region: DUF1043; cl11473
755732002188	A predicted NlpC/p60-like peptidase; Region: BtrH; pfam14399
755732002189	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
755732002190	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
755732002191	putative active site [active]
755732002192	putative NTP binding site [chemical binding]; other site
755732002193	putative nucleic acid binding site [nucleotide binding]; other site
755732002194	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
755732002195	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732002196	putative metal binding site [ion binding]; other site
755732002197	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
755732002198	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
755732002199	NADP binding site [chemical binding]; other site
755732002200	homopentamer interface [polypeptide binding]; other site
755732002201	substrate binding site [chemical binding]; other site
755732002202	active site
755732002203	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
755732002204	active site
755732002205	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
755732002206	homodecamer interface [polypeptide binding]; other site
755732002207	GTP cyclohydrolase I; Provisional; Region: PLN03044
755732002208	active site
755732002209	putative catalytic site residues [active]
755732002210	zinc binding site [ion binding]; other site
755732002211	GTP-CH-I/GFRP interaction surface; other site
755732002212	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
755732002213	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
755732002214	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
755732002215	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
755732002216	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
755732002217	GH3 auxin-responsive promoter; Region: GH3; pfam03321
755732002218	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
755732002219	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
755732002220	Substrate-binding site [chemical binding]; other site
755732002221	Substrate specificity [chemical binding]; other site
755732002222	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002223	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732002224	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732002225	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732002226	DNA binding residues [nucleotide binding]
755732002227	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
755732002228	catalytic core [active]
755732002229	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
755732002230	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
755732002231	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732002232	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732002233	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
755732002234	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732002235	Ketosteroid isomerase-related protein [General function prediction only]; Region: COG3631
755732002236	Type III pantothenate kinase; Region: Pan_kinase; cl17198
755732002237	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
755732002238	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732002239	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
755732002240	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
755732002241	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
755732002242	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
755732002243	substrate binding pocket [chemical binding]; other site
755732002244	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
755732002245	B12 binding site [chemical binding]; other site
755732002246	cobalt ligand [ion binding]; other site
755732002247	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
755732002248	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002249	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732002250	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002251	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002252	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732002253	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002254	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002255	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002256	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732002257	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
755732002258	RNA/DNA hybrid binding site [nucleotide binding]; other site
755732002259	active site
755732002260	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
755732002261	proline aminopeptidase P II; Provisional; Region: PRK10879
755732002262	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
755732002263	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
755732002264	active site
755732002265	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732002266	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
755732002267	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002268	active site
755732002269	phosphorylation site [posttranslational modification]
755732002270	intermolecular recognition site; other site
755732002271	dimerization interface [polypeptide binding]; other site
755732002272	LytTr DNA-binding domain; Region: LytTR; smart00850
755732002273	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732002274	Histidine kinase; Region: His_kinase; pfam06580
755732002275	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732002276	Mg2+ binding site [ion binding]; other site
755732002277	G-X-G motif; other site
755732002278	thiamine-monophosphate kinase; Region: thiL; TIGR01379
755732002279	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
755732002280	ATP binding site [chemical binding]; other site
755732002281	dimerization interface [polypeptide binding]; other site
755732002282	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
755732002283	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
755732002284	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002285	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
755732002286	active site
755732002287	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
755732002288	homotrimer interaction site [polypeptide binding]; other site
755732002289	putative active site [active]
755732002290	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
755732002291	active site
755732002292	DNA binding site [nucleotide binding]
755732002293	Int/Topo IB signature motif; other site
755732002294	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732002295	sequence-specific DNA binding site [nucleotide binding]; other site
755732002296	salt bridge; other site
755732002297	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
755732002298	AAA ATPase domain; Region: AAA_16; pfam13191
755732002299	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
755732002300	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
755732002301	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
755732002302	NodB motif; other site
755732002303	active site
755732002304	catalytic site [active]
755732002305	metal binding site [ion binding]; metal-binding site
755732002306	Protein of unknown function (DUF2480); Region: DUF2480; pfam10652
755732002307	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
755732002308	acyl-CoA esterase; Provisional; Region: PRK10673
755732002309	Transposase IS200 like; Region: Y1_Tnp; cl00848
755732002310	Gram-negative bacterial tonB protein; Region: TonB; cl10048
755732002311	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002312	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002313	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002314	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
755732002315	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
755732002316	substrate binding site [chemical binding]; other site
755732002317	dimer interface [polypeptide binding]; other site
755732002318	NADP binding site [chemical binding]; other site
755732002319	catalytic residues [active]
755732002320	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
755732002321	active site 2 [active]
755732002322	active site 1 [active]
755732002323	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
755732002324	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
755732002325	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002326	PBP superfamily domain; Region: PBP_like_2; pfam12849
755732002327	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002328	binding surface
755732002329	TPR motif; other site
755732002330	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002331	TPR motif; other site
755732002332	binding surface
755732002333	TPR repeat; Region: TPR_11; pfam13414
755732002334	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002335	TPR motif; other site
755732002336	binding surface
755732002337	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002338	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
755732002339	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
755732002340	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
755732002341	alpha subunit interaction interface [polypeptide binding]; other site
755732002342	Walker A motif; other site
755732002343	ATP binding site [chemical binding]; other site
755732002344	Walker B motif; other site
755732002345	inhibitor binding site; inhibition site
755732002346	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
755732002347	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
755732002348	gamma subunit interface [polypeptide binding]; other site
755732002349	LBP interface [polypeptide binding]; other site
755732002350	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
755732002351	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
755732002352	catalytic residue [active]
755732002353	putative FPP diphosphate  binding site; other site
755732002354	putative FPP binding hydrophobic cleft; other site
755732002355	dimer interface [polypeptide binding]; other site
755732002356	putative IPP diphosphate binding site; other site
755732002357	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
755732002358	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
755732002359	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
755732002360	Surface antigen; Region: Bac_surface_Ag; pfam01103
755732002361	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
755732002362	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
755732002363	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
755732002364	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
755732002365	putative active site [active]
755732002366	metal binding site [ion binding]; metal-binding site
755732002367	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
755732002368	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
755732002369	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732002370	putative heme d1 biosynthesis radical SAM protein NirJ2; Region: rSAM_NirJ2; TIGR04055
755732002371	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732002372	FeS/SAM binding site; other site
755732002373	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
755732002374	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
755732002375	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
755732002376	substrate-cofactor binding pocket; other site
755732002377	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732002378	catalytic residue [active]
755732002379	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex; Region: CESA_CaSu_A2; cd06437
755732002380	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
755732002381	DXD motif; other site
755732002382	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
755732002383	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
755732002384	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
755732002385	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
755732002386	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
755732002387	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
755732002388	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
755732002389	ligand binding site [chemical binding]; other site
755732002390	homodimer interface [polypeptide binding]; other site
755732002391	NAD(P) binding site [chemical binding]; other site
755732002392	trimer interface B [polypeptide binding]; other site
755732002393	trimer interface A [polypeptide binding]; other site
755732002394	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
755732002395	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
755732002396	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
755732002397	NAD(P) binding site [chemical binding]; other site
755732002398	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
755732002399	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002400	active site
755732002401	phosphorylation site [posttranslational modification]
755732002402	intermolecular recognition site; other site
755732002403	dimerization interface [polypeptide binding]; other site
755732002404	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732002405	Walker A motif; other site
755732002406	ATP binding site [chemical binding]; other site
755732002407	Walker B motif; other site
755732002408	arginine finger; other site
755732002409	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
755732002410	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732002411	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732002412	dimer interface [polypeptide binding]; other site
755732002413	phosphorylation site [posttranslational modification]
755732002414	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732002415	ATP binding site [chemical binding]; other site
755732002416	Mg2+ binding site [ion binding]; other site
755732002417	G-X-G motif; other site
755732002418	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
755732002419	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
755732002420	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
755732002421	Sulfate transporter family; Region: Sulfate_transp; pfam00916
755732002422	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
755732002423	active site clefts [active]
755732002424	zinc binding site [ion binding]; other site
755732002425	dimer interface [polypeptide binding]; other site
755732002426	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
755732002427	A new structural DNA glycosylase; Region: AlkD_like; cl11434
755732002428	active site
755732002429	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732002430	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732002431	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732002432	DNA binding residues [nucleotide binding]
755732002433	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
755732002434	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
755732002435	Peptidase family M28; Region: Peptidase_M28; pfam04389
755732002436	metal binding site [ion binding]; metal-binding site
755732002437	thymidine kinase; Provisional; Region: PRK04296
755732002438	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
755732002439	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
755732002440	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732002441	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
755732002442	active site
755732002443	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
755732002444	dimer interface [polypeptide binding]; other site
755732002445	substrate binding site [chemical binding]; other site
755732002446	catalytic residues [active]
755732002447	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
755732002448	ligand binding site [chemical binding]; other site
755732002449	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732002450	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732002451	ligand binding site [chemical binding]; other site
755732002452	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
755732002453	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
755732002454	DNA binding site [nucleotide binding]
755732002455	active site
755732002456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
755732002457	SPFH domain / Band 7 family; Region: Band_7; pfam01145
755732002458	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
755732002459	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
755732002460	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
755732002461	core domain interface [polypeptide binding]; other site
755732002462	delta subunit interface [polypeptide binding]; other site
755732002463	epsilon subunit interface [polypeptide binding]; other site
755732002464	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
755732002465	four helix bundle protein; Region: TIGR02436
755732002466	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
755732002467	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
755732002468	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
755732002469	beta subunit interaction interface [polypeptide binding]; other site
755732002470	Walker A motif; other site
755732002471	ATP binding site [chemical binding]; other site
755732002472	Walker B motif; other site
755732002473	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
755732002474	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
755732002475	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
755732002476	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
755732002477	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
755732002478	ATP synthase subunit C; Region: ATP-synt_C; cl00466
755732002479	ATP synthase A chain; Region: ATP-synt_A; cl00413
755732002480	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; cl09754
755732002481	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
755732002482	Colicin V production protein; Region: Colicin_V; pfam02674
755732002483	hypothetical protein; Provisional; Region: PRK12378
755732002484	RIP metalloprotease RseP; Region: TIGR00054
755732002485	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
755732002486	active site
755732002487	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
755732002488	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
755732002489	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
755732002490	putative substrate binding region [chemical binding]; other site
755732002491	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
755732002492	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732002493	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
755732002494	active site
755732002495	catalytic residues [active]
755732002496	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
755732002497	4Fe-4S binding domain; Region: Fer4; cl02805
755732002498	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
755732002499	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
755732002500	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
755732002501	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732002502	Walker A motif; other site
755732002503	ATP binding site [chemical binding]; other site
755732002504	Walker B motif; other site
755732002505	arginine finger; other site
755732002506	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
755732002507	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
755732002508	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
755732002509	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
755732002510	Cytochrome c; Region: Cytochrom_C; pfam00034
755732002511	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
755732002512	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
755732002513	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
755732002514	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
755732002515	molybdopterin cofactor binding site; other site
755732002516	The MopB_CT_PHLH CD includes a group of related uncharacterized putative hydrogenase-like homologs (PHLH) of molybdopterin binding proteins. This CD is of the PHLH region homologous to the conserved molybdopterin-binding C-terminal (MopB_CT) region...; Region: MopB_CT_PHLH; cd02784
755732002517	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
755732002518	Cytochrome c; Region: Cytochrom_C; cl11414
755732002519	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
755732002520	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
755732002521	heme-binding residues [chemical binding]; other site
755732002522	HI0933-like protein; Region: HI0933_like; pfam03486
755732002523	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732002524	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
755732002525	ATP-grasp domain; Region: ATP-grasp; pfam02222
755732002526	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
755732002527	putative metal binding residues [ion binding]; other site
755732002528	signature motif; other site
755732002529	dimer interface [polypeptide binding]; other site
755732002530	active site
755732002531	polyP binding site; other site
755732002532	substrate binding site [chemical binding]; other site
755732002533	acceptor-phosphate pocket; other site
755732002534	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732002535	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
755732002536	Protein of unknown function, DUF399; Region: DUF399; cl01139
755732002537	Sulfatase; Region: Sulfatase; pfam00884
755732002538	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
755732002539	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
755732002540	Etoposide-induced protein 2.4 (EI24); Region: EI24; cl01126
755732002541	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
755732002542	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
755732002543	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
755732002544	active site
755732002545	substrate binding site [chemical binding]; other site
755732002546	coenzyme B12 binding site [chemical binding]; other site
755732002547	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
755732002548	B12 binding site [chemical binding]; other site
755732002549	cobalt ligand [ion binding]; other site
755732002550	Stage II sporulation protein; Region: SpoIID; pfam08486
755732002551	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
755732002552	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
755732002553	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
755732002554	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
755732002555	PQQ-like domain; Region: PQQ_2; pfam13360
755732002556	DNA polymerase I; Provisional; Region: PRK05755
755732002557	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
755732002558	active site
755732002559	metal binding site 1 [ion binding]; metal-binding site
755732002560	putative 5' ssDNA interaction site; other site
755732002561	metal binding site 3; metal-binding site
755732002562	metal binding site 2 [ion binding]; metal-binding site
755732002563	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
755732002564	putative DNA binding site [nucleotide binding]; other site
755732002565	putative metal binding site [ion binding]; other site
755732002566	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
755732002567	active site
755732002568	catalytic site [active]
755732002569	substrate binding site [chemical binding]; other site
755732002570	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
755732002571	active site
755732002572	DNA binding site [nucleotide binding]
755732002573	catalytic site [active]
755732002574	Peptidase M36 family also known as fungalysin family; Region: M36; cd09596
755732002575	PA_subtilisin_1: Protease-associated domain containing subtilisin-like proteases, subgroup 1. A subgroup of PA domain-containing subtilisin-like proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined; Region: PA_subtilisin_1; cd04818
755732002576	PA/protease or protease-like domain interface [polypeptide binding]; other site
755732002577	Peptidase M36 family also known as fungalysin family; Region: M36; cd09596
755732002578	Fungalysin metallopeptidase (M36); Region: Peptidase_M36; pfam02128
755732002579	Zn binding site [ion binding]; other site
755732002580	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002581	PhoD-like phosphatase; Region: PhoD; pfam09423
755732002582	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
755732002583	putative active site [active]
755732002584	putative metal binding site [ion binding]; other site
755732002585	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
755732002586	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002587	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002588	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
755732002589	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
755732002590	active site
755732002591	metal binding site [ion binding]; metal-binding site
755732002592	Part of AAA domain; Region: AAA_19; pfam13245
755732002593	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
755732002594	AAA domain; Region: AAA_12; pfam13087
755732002595	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
755732002596	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
755732002597	homodimer interface [polypeptide binding]; other site
755732002598	substrate-cofactor binding pocket; other site
755732002599	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732002600	catalytic residue [active]
755732002601	short chain dehydrogenase; Provisional; Region: PRK06924
755732002602	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732002603	NAD(P) binding site [chemical binding]; other site
755732002604	active site
755732002605	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732002606	active site
755732002607	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732002608	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732002609	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002610	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732002611	active site
755732002612	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732002613	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732002614	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002615	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
755732002616	active site
755732002617	catalytic site [active]
755732002618	substrate binding site [chemical binding]; other site
755732002619	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
755732002620	GAF domain; Region: GAF_2; pfam13185
755732002621	Bacterial Ig-like domain; Region: Big_5; pfam13205
755732002622	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
755732002623	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
755732002624	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
755732002625	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732002626	active site
755732002627	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
755732002628	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
755732002629	5S rRNA interface [nucleotide binding]; other site
755732002630	CTC domain interface [polypeptide binding]; other site
755732002631	L16 interface [polypeptide binding]; other site
755732002632	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
755732002633	substrate binding site [chemical binding]; other site
755732002634	amidase catalytic site [active]
755732002635	Zn binding residues [ion binding]; other site
755732002636	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
755732002637	heterodimerization interface [polypeptide binding]; other site
755732002638	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002639	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
755732002640	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732002641	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732002642	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
755732002643	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
755732002644	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
755732002645	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
755732002646	homotrimer interaction site [polypeptide binding]; other site
755732002647	putative active site [active]
755732002648	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732002649	S-adenosylmethionine binding site [chemical binding]; other site
755732002650	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732002651	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002652	active site
755732002653	phosphorylation site [posttranslational modification]
755732002654	intermolecular recognition site; other site
755732002655	dimerization interface [polypeptide binding]; other site
755732002656	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732002657	dimerization interface [polypeptide binding]; other site
755732002658	DNA binding residues [nucleotide binding]
755732002659	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732002660	Histidine kinase; Region: HisKA_3; pfam07730
755732002661	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732002662	ATP binding site [chemical binding]; other site
755732002663	Mg2+ binding site [ion binding]; other site
755732002664	G-X-G motif; other site
755732002665	Protein of unknown function (DUF3606); Region: DUF3606; pfam12244
755732002666	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
755732002667	hypothetical protein; Provisional; Region: PRK00955
755732002668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732002669	Cortical protein marker for cell polarity; Region: Rax2; pfam12768
755732002670	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
755732002671	multifunctional aminopeptidase A; Provisional; Region: PRK00913
755732002672	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
755732002673	interface (dimer of trimers) [polypeptide binding]; other site
755732002674	Substrate-binding/catalytic site; other site
755732002675	Zn-binding sites [ion binding]; other site
755732002676	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
755732002677	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
755732002678	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
755732002679	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
755732002680	putative phosphate acyltransferase; Provisional; Region: PRK05331
755732002681	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
755732002682	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
755732002683	dimer interface [polypeptide binding]; other site
755732002684	active site
755732002685	CoA binding pocket [chemical binding]; other site
755732002686	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
755732002687	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
755732002688	carboxyltransferase (CT) interaction site; other site
755732002689	biotinylation site [posttranslational modification]; other site
755732002690	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
755732002691	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
755732002692	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
755732002693	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
755732002694	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
755732002695	dimerization interface [polypeptide binding]; other site
755732002696	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732002697	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002698	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002699	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732002700	Family description; Region: VCBS; pfam13517
755732002701	Family description; Region: VCBS; pfam13517
755732002702	Family description; Region: VCBS; pfam13517
755732002703	Family description; Region: VCBS; pfam13517
755732002704	Family description; Region: VCBS; pfam13517
755732002705	Family description; Region: VCBS; pfam13517
755732002706	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002707	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732002708	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732002709	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732002710	DNA binding residues [nucleotide binding]
755732002711	Integral membrane protein DUF95; Region: DUF95; pfam01944
755732002712	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
755732002713	MoxR-like ATPases [General function prediction only]; Region: COG0714
755732002714	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732002715	Walker A motif; other site
755732002716	ATP binding site [chemical binding]; other site
755732002717	Walker B motif; other site
755732002718	arginine finger; other site
755732002719	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
755732002720	Protein of unknown function DUF58; Region: DUF58; pfam01882
755732002721	von Willebrand factor type A domain; Region: VWA_2; pfam13519
755732002722	metal ion-dependent adhesion site (MIDAS); other site
755732002723	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
755732002724	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
755732002725	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002726	MepB protein; Region: MepB; cl01985
755732002727	Domain of unknown function (DUF4259); Region: DUF4259; pfam14078
755732002728	aldehyde dehydrogenase family 7 member; Region: PLN02315
755732002729	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
755732002730	tetrameric interface [polypeptide binding]; other site
755732002731	NAD binding site [chemical binding]; other site
755732002732	catalytic residues [active]
755732002733	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002734	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002735	binding surface
755732002736	TPR motif; other site
755732002737	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002738	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002739	Tetratricopeptide repeat; Region: TPR_10; cl17452
755732002740	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002741	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002742	binding surface
755732002743	TPR motif; other site
755732002744	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002745	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732002746	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
755732002747	Domain of unknown function (DUF4424); Region: DUF4424; pfam14415
755732002748	YARHG domain; Region: YARHG; pfam13308
755732002749	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732002750	CHAP domain; Region: CHAP; pfam05257
755732002751	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732002752	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
755732002753	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
755732002754	peptide binding site [polypeptide binding]; other site
755732002755	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732002756	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
755732002757	dimer interface [polypeptide binding]; other site
755732002758	substrate binding site [chemical binding]; other site
755732002759	metal binding site [ion binding]; metal-binding site
755732002760	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
755732002761	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732002762	motif II; other site
755732002763	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
755732002764	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
755732002765	TPP-binding site [chemical binding]; other site
755732002766	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
755732002767	dimer interface [polypeptide binding]; other site
755732002768	PYR/PP interface [polypeptide binding]; other site
755732002769	TPP binding site [chemical binding]; other site
755732002770	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
755732002771	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
755732002772	E3 interaction surface; other site
755732002773	lipoyl attachment site [posttranslational modification]; other site
755732002774	e3 binding domain; Region: E3_binding; pfam02817
755732002775	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
755732002776	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732002777	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
755732002778	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002779	binding surface
755732002780	TPR motif; other site
755732002781	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002782	binding surface
755732002783	TPR motif; other site
755732002784	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
755732002785	Domain of unknown function (DUF4377); Region: DUF4377; pfam14302
755732002786	META domain; Region: META; pfam03724
755732002787	META domain; Region: META; pfam03724
755732002788	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
755732002789	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
755732002790	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002791	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
755732002792	catalytic triad [active]
755732002793	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
755732002794	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
755732002795	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
755732002796	trmE is a tRNA modification GTPase; Region: trmE; cd04164
755732002797	G1 box; other site
755732002798	GTP/Mg2+ binding site [chemical binding]; other site
755732002799	Switch I region; other site
755732002800	G2 box; other site
755732002801	Switch II region; other site
755732002802	G3 box; other site
755732002803	G4 box; other site
755732002804	G5 box; other site
755732002805	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
755732002806	Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; Region: MAM; cl02479
755732002807	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002808	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
755732002809	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
755732002810	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
755732002811	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732002812	Walker A/P-loop; other site
755732002813	ATP binding site [chemical binding]; other site
755732002814	Q-loop/lid; other site
755732002815	ABC transporter signature motif; other site
755732002816	Walker B; other site
755732002817	D-loop; other site
755732002818	H-loop/switch region; other site
755732002819	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
755732002820	nucleoside/Zn binding site; other site
755732002821	dimer interface [polypeptide binding]; other site
755732002822	catalytic motif [active]
755732002823	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
755732002824	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
755732002825	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
755732002826	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
755732002827	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
755732002828	dimer interface [polypeptide binding]; other site
755732002829	motif 1; other site
755732002830	active site
755732002831	motif 2; other site
755732002832	motif 3; other site
755732002833	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
755732002834	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732002835	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002836	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002837	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732002838	TPR motif; other site
755732002839	binding surface
755732002840	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732002841	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
755732002842	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
755732002843	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
755732002844	active site
755732002845	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
755732002846	CutC family; Region: CutC; cl01218
755732002847	Metallo-peptidase family M12B Reprolysin-like; Region: Reprolysin_2; pfam13574
755732002848	active site
755732002849	Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family; Region: GPI-anchored; pfam10342
755732002850	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002851	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
755732002852	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
755732002853	AMP nucleosidase; Provisional; Region: PRK07115
755732002854	AAA domain; Region: AAA_14; pfam13173
755732002855	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
755732002856	TraB family; Region: TraB; pfam01963
755732002857	imidazolonepropionase; Validated; Region: PRK09356
755732002858	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
755732002859	active site
755732002860	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
755732002861	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732002862	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732002863	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732002864	LysE type translocator; Region: LysE; cl00565
755732002865	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
755732002866	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
755732002867	Ligand binding site; other site
755732002868	Putative Catalytic site; other site
755732002869	DXD motif; other site
755732002870	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
755732002871	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
755732002872	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
755732002873	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
755732002874	Transglycosylase; Region: Transgly; pfam00912
755732002875	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
755732002876	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
755732002877	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
755732002878	active site
755732002879	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
755732002880	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
755732002881	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
755732002882	active site
755732002883	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
755732002884	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732002885	FeS/SAM binding site; other site
755732002886	HemN C-terminal domain; Region: HemN_C; pfam06969
755732002887	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
755732002888	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
755732002889	active site
755732002890	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
755732002891	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
755732002892	active site
755732002893	metal binding site [ion binding]; metal-binding site
755732002894	Sporulation related domain; Region: SPOR; pfam05036
755732002895	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
755732002896	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
755732002897	dimer interface [polypeptide binding]; other site
755732002898	ssDNA binding site [nucleotide binding]; other site
755732002899	tetramer (dimer of dimers) interface [polypeptide binding]; other site
755732002900	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
755732002901	Transposase; Region: DDE_Tnp_ISL3; pfam01610
755732002902	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
755732002903	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
755732002904	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
755732002905	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
755732002906	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
755732002907	tetramer interface [polypeptide binding]; other site
755732002908	heme binding pocket [chemical binding]; other site
755732002909	NADPH binding site [chemical binding]; other site
755732002910	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
755732002911	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002912	active site
755732002913	phosphorylation site [posttranslational modification]
755732002914	intermolecular recognition site; other site
755732002915	dimerization interface [polypeptide binding]; other site
755732002916	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732002917	Walker A motif; other site
755732002918	ATP binding site [chemical binding]; other site
755732002919	Walker B motif; other site
755732002920	arginine finger; other site
755732002921	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732002922	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732002923	dimer interface [polypeptide binding]; other site
755732002924	phosphorylation site [posttranslational modification]
755732002925	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732002926	ATP binding site [chemical binding]; other site
755732002927	Mg2+ binding site [ion binding]; other site
755732002928	G-X-G motif; other site
755732002929	Response regulator receiver domain; Region: Response_reg; pfam00072
755732002930	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732002931	active site
755732002932	phosphorylation site [posttranslational modification]
755732002933	intermolecular recognition site; other site
755732002934	dimerization interface [polypeptide binding]; other site
755732002935	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
755732002936	HipA N-terminal domain; Region: Couple_hipA; pfam13657
755732002937	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
755732002938	HipA-like N-terminal domain; Region: HipA_N; pfam07805
755732002939	HipA-like C-terminal domain; Region: HipA_C; pfam07804
755732002940	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732002941	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732002942	non-specific DNA binding site [nucleotide binding]; other site
755732002943	salt bridge; other site
755732002944	sequence-specific DNA binding site [nucleotide binding]; other site
755732002945	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
755732002946	CotH protein; Region: CotH; pfam08757
755732002947	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002948	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
755732002949	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
755732002950	RNA binding surface [nucleotide binding]; other site
755732002951	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
755732002952	active site
755732002953	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
755732002954	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
755732002955	dimer interface [polypeptide binding]; other site
755732002956	putative anticodon binding site; other site
755732002957	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
755732002958	motif 1; other site
755732002959	active site
755732002960	motif 2; other site
755732002961	motif 3; other site
755732002962	conserved hypothetical protein, HNE_0200 family; Region: chp_HNE_0200; TIGR03806
755732002963	Family description; Region: VCBS; pfam13517
755732002964	Family description; Region: VCBS; pfam13517
755732002965	Family description; Region: VCBS; pfam13517
755732002966	Family description; Region: VCBS; pfam13517
755732002967	Family description; Region: VCBS; pfam13517
755732002968	Family description; Region: VCBS; pfam13517
755732002969	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
755732002970	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002971	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
755732002972	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732002973	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732002974	ABC transporter; Region: ABC_tran_2; pfam12848
755732002975	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732002976	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
755732002977	Recombination protein O N terminal; Region: RecO_N; pfam11967
755732002978	Recombination protein O C terminal; Region: RecO_C; pfam02565
755732002979	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
755732002980	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
755732002981	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
755732002982	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
755732002983	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732002984	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732002985	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
755732002986	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
755732002987	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
755732002988	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732002989	exopolyphosphatase; Region: exo_poly_only; TIGR03706
755732002990	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
755732002991	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732002992	Site-specific recombinase; Region: SpecificRecomb; cl15411
755732002993	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
755732002994	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732002995	active site
755732002996	HIGH motif; other site
755732002997	nucleotide binding site [chemical binding]; other site
755732002998	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
755732002999	active site
755732003000	KMSKS motif; other site
755732003001	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
755732003002	tRNA binding surface [nucleotide binding]; other site
755732003003	anticodon binding site; other site
755732003004	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
755732003005	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732003006	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732003007	DNA binding residues [nucleotide binding]
755732003008	Anti-sigma-K factor rskA; Region: RskA; pfam10099
755732003009	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
755732003010	dimer interface [polypeptide binding]; other site
755732003011	catalytic triad [active]
755732003012	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
755732003013	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
755732003014	NAD binding site [chemical binding]; other site
755732003015	catalytic residues [active]
755732003016	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732003017	ligand binding site [chemical binding]; other site
755732003018	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732003019	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732003020	active site
755732003021	phosphorylation site [posttranslational modification]
755732003022	intermolecular recognition site; other site
755732003023	dimerization interface [polypeptide binding]; other site
755732003024	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732003025	DNA binding site [nucleotide binding]
755732003026	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732003027	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732003028	dimer interface [polypeptide binding]; other site
755732003029	phosphorylation site [posttranslational modification]
755732003030	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732003031	ATP binding site [chemical binding]; other site
755732003032	Mg2+ binding site [ion binding]; other site
755732003033	G-X-G motif; other site
755732003034	helicase 45; Provisional; Region: PTZ00424
755732003035	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
755732003036	ATP binding site [chemical binding]; other site
755732003037	putative Mg++ binding site [ion binding]; other site
755732003038	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732003039	nucleotide binding region [chemical binding]; other site
755732003040	ATP-binding site [chemical binding]; other site
755732003041	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003042	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
755732003043	Fasciclin domain; Region: Fasciclin; pfam02469
755732003044	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
755732003045	MgtE intracellular N domain; Region: MgtE_N; pfam03448
755732003046	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
755732003047	Divalent cation transporter; Region: MgtE; pfam01769
755732003048	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732003049	C-terminal peptidase (prc); Region: prc; TIGR00225
755732003050	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
755732003051	protein binding site [polypeptide binding]; other site
755732003052	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
755732003053	Catalytic dyad [active]
755732003054	ribonuclease P; Reviewed; Region: rnpA; PRK01903
755732003055	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
755732003056	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732003057	active site
755732003058	HIGH motif; other site
755732003059	nucleotide binding site [chemical binding]; other site
755732003060	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
755732003061	KMSKS motif; other site
755732003062	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
755732003063	tRNA binding surface [nucleotide binding]; other site
755732003064	anticodon binding site; other site
755732003065	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
755732003066	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
755732003067	cofactor binding site; other site
755732003068	DNA binding site [nucleotide binding]
755732003069	substrate interaction site [chemical binding]; other site
755732003070	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
755732003071	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
755732003072	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
755732003073	putative DNA binding site [nucleotide binding]; other site
755732003074	putative Zn2+ binding site [ion binding]; other site
755732003075	AsnC family; Region: AsnC_trans_reg; pfam01037
755732003076	GxxExxY protein; Region: GxxExxY; TIGR04256
755732003077	YtxH-like protein; Region: YtxH; pfam12732
755732003078	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
755732003079	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
755732003080	NAD binding site [chemical binding]; other site
755732003081	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
755732003082	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
755732003083	active site
755732003084	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
755732003085	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
755732003086	acyl-activating enzyme (AAE) consensus motif; other site
755732003087	active site
755732003088	AMP binding site [chemical binding]; other site
755732003089	CoA binding site [chemical binding]; other site
755732003090	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
755732003091	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732003092	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
755732003093	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732003094	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
755732003095	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
755732003096	putative acyl-acceptor binding pocket; other site
755732003097	Methyltransferase domain; Region: Methyltransf_31; pfam13847
755732003098	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732003099	S-adenosylmethionine binding site [chemical binding]; other site
755732003100	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
755732003101	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732003102	O-methyltransferase; Region: Methyltransf_2; pfam00891
755732003103	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
755732003104	active sites [active]
755732003105	tetramer interface [polypeptide binding]; other site
755732003106	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732003107	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
755732003108	NAD(P) binding site [chemical binding]; other site
755732003109	active site
755732003110	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
755732003111	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
755732003112	dimer interface [polypeptide binding]; other site
755732003113	active site
755732003114	Phosphopantetheine attachment site; Region: PP-binding; cl09936
755732003115	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
755732003116	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
755732003117	putative acyl-acceptor binding pocket; other site
755732003118	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
755732003119	active site 2 [active]
755732003120	active site 1 [active]
755732003121	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
755732003122	active site
755732003123	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
755732003124	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
755732003125	dimer interface [polypeptide binding]; other site
755732003126	active site
755732003127	Phosphopantetheine attachment site; Region: PP-binding; cl09936
755732003128	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
755732003129	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
755732003130	dimer interface [polypeptide binding]; other site
755732003131	active site
755732003132	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
755732003133	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
755732003134	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
755732003135	NodB motif; other site
755732003136	active site
755732003137	catalytic site [active]
755732003138	metal binding site [ion binding]; metal-binding site
755732003139	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
755732003140	FabA/Z, beta-hydroxyacyl-acyl carrier protein (ACP)-dehydratases: One of several distinct enzyme types of the dissociative, type II, fatty acid synthase system (found in bacteria and plants) required to complete successive cycles of fatty acid elongation; Region: FabA_FabZ; cd00493
755732003141	active site 2 [active]
755732003142	dimer interface [polypeptide binding]; other site
755732003143	active site 1 [active]
755732003144	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
755732003145	Ligand binding site; other site
755732003146	Putative Catalytic site; other site
755732003147	DXD motif; other site
755732003148	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; pfam09835
755732003149	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK06816
755732003150	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
755732003151	dimer interface [polypeptide binding]; other site
755732003152	active site
755732003153	A predicted NlpC/p60-like peptidase; Region: BtrH; pfam14399
755732003154	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
755732003155	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732003156	Walker A/P-loop; other site
755732003157	ATP binding site [chemical binding]; other site
755732003158	Q-loop/lid; other site
755732003159	ABC transporter signature motif; other site
755732003160	Walker B; other site
755732003161	D-loop; other site
755732003162	H-loop/switch region; other site
755732003163	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
755732003164	ABC-2 type transporter; Region: ABC2_membrane; cl17235
755732003165	Phosphopantetheine attachment site; Region: PP-binding; cl09936
755732003166	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
755732003167	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
755732003168	dimer interface [polypeptide binding]; other site
755732003169	active site
755732003170	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
755732003171	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; cl01132
755732003172	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
755732003173	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
755732003174	active site
755732003175	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
755732003176	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
755732003177	domain interfaces; other site
755732003178	active site
755732003179	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
755732003180	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
755732003181	NAD(P) binding pocket [chemical binding]; other site
755732003182	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
755732003183	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
755732003184	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
755732003185	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
755732003186	DHH family; Region: DHH; pfam01368
755732003187	DHHA1 domain; Region: DHHA1; pfam02272
755732003188	twin arginine-targeting protein translocase, TatA/E family; Region: tatAE; TIGR01411
755732003189	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
755732003190	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
755732003191	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
755732003192	N-acetyl-D-glucosamine binding site [chemical binding]; other site
755732003193	catalytic residue [active]
755732003194	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732003195	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732003196	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
755732003197	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
755732003198	putative metal binding site; other site
755732003199	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
755732003200	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732003201	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
755732003202	putative active site [active]
755732003203	Phosphoglycerate kinase; Region: PGK; pfam00162
755732003204	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
755732003205	substrate binding site [chemical binding]; other site
755732003206	hinge regions; other site
755732003207	ADP binding site [chemical binding]; other site
755732003208	catalytic site [active]
755732003209	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
755732003210	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
755732003211	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
755732003212	putative acyl-acceptor binding pocket; other site
755732003213	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
755732003214	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
755732003215	active site
755732003216	HIGH motif; other site
755732003217	dimer interface [polypeptide binding]; other site
755732003218	KMSKS motif; other site
755732003219	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
755732003220	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
755732003221	polyphosphate kinase; Provisional; Region: PRK05443
755732003222	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
755732003223	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
755732003224	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
755732003225	domain interface [polypeptide binding]; other site
755732003226	active site
755732003227	catalytic site [active]
755732003228	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
755732003229	domain interface [polypeptide binding]; other site
755732003230	active site
755732003231	catalytic site [active]
755732003232	Histidine kinase; Region: His_kinase; pfam06580
755732003233	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732003234	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
755732003235	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
755732003236	dimer interface [polypeptide binding]; other site
755732003237	anticodon binding site; other site
755732003238	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
755732003239	homodimer interface [polypeptide binding]; other site
755732003240	motif 1; other site
755732003241	active site
755732003242	motif 2; other site
755732003243	GAD domain; Region: GAD; pfam02938
755732003244	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
755732003245	motif 3; other site
755732003246	NlpE N-terminal domain; Region: NlpE; pfam04170
755732003247	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
755732003248	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
755732003249	NAD(P) binding site [chemical binding]; other site
755732003250	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732003251	Ligand Binding Site [chemical binding]; other site
755732003252	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732003253	Predicted methyltransferases [General function prediction only]; Region: COG0313
755732003254	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
755732003255	putative SAM binding site [chemical binding]; other site
755732003256	putative homodimer interface [polypeptide binding]; other site
755732003257	RDD family; Region: RDD; pfam06271
755732003258	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
755732003259	putative catalytic site [active]
755732003260	putative metal binding site [ion binding]; other site
755732003261	putative phosphate binding site [ion binding]; other site
755732003262	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
755732003263	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
755732003264	oligomer interface [polypeptide binding]; other site
755732003265	active site
755732003266	metal binding site [ion binding]; metal-binding site
755732003267	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732003268	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003269	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732003270	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732003271	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732003272	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
755732003273	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
755732003274	Cu(I) binding site [ion binding]; other site
755732003275	L-fucose transporter; Provisional; Region: PRK10133; cl17665
755732003276	L-fucose transporter; Provisional; Region: PRK10133; cl17665
755732003277	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
755732003278	putative Iron-sulfur protein interface [polypeptide binding]; other site
755732003279	proximal heme binding site [chemical binding]; other site
755732003280	putative dimer interface [polypeptide binding]; other site
755732003281	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
755732003282	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
755732003283	L-aspartate oxidase; Provisional; Region: PRK06175
755732003284	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
755732003285	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
755732003286	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
755732003287	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
755732003288	PA_subtilisin_1: Protease-associated domain containing subtilisin-like proteases, subgroup 1. A subgroup of PA domain-containing subtilisin-like proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined; Region: PA_subtilisin_1; cd04818
755732003289	PA/protease or protease-like domain interface [polypeptide binding]; other site
755732003290	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003291	Domain of unknown function (DUF2341); Region: DUF2341; pfam10102
755732003292	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003293	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732003294	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732003295	dimer interface [polypeptide binding]; other site
755732003296	phosphorylation site [posttranslational modification]
755732003297	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732003298	ATP binding site [chemical binding]; other site
755732003299	Mg2+ binding site [ion binding]; other site
755732003300	G-X-G motif; other site
755732003301	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
755732003302	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
755732003303	active site
755732003304	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
755732003305	putative catalytic residue [active]
755732003306	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
755732003307	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003308	DNA repair protein RadA; Provisional; Region: PRK11823
755732003309	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
755732003310	Walker A motif/ATP binding site; other site
755732003311	ATP binding site [chemical binding]; other site
755732003312	Walker B motif; other site
755732003313	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
755732003314	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003315	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003316	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732003317	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003318	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
755732003319	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
755732003320	putative active site [active]
755732003321	PhoH-like protein; Region: PhoH; pfam02562
755732003322	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
755732003323	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; pfam09995
755732003324	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003325	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
755732003326	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
755732003327	Cl- selectivity filter; other site
755732003328	Cl- binding residues [ion binding]; other site
755732003329	pore gating glutamate residue; other site
755732003330	dimer interface [polypeptide binding]; other site
755732003331	GxxExxY protein; Region: GxxExxY; TIGR04256
755732003332	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
755732003333	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
755732003334	active site
755732003335	HIGH motif; other site
755732003336	KMSKS motif; other site
755732003337	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
755732003338	tRNA binding surface [nucleotide binding]; other site
755732003339	anticodon binding site; other site
755732003340	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
755732003341	dimer interface [polypeptide binding]; other site
755732003342	putative tRNA-binding site [nucleotide binding]; other site
755732003343	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
755732003344	ligand binding site [chemical binding]; other site
755732003345	dimer interface [polypeptide binding]; other site
755732003346	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732003347	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
755732003348	active site
755732003349	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
755732003350	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
755732003351	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
755732003352	generic binding surface II; other site
755732003353	generic binding surface I; other site
755732003354	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
755732003355	FeoA domain; Region: FeoA; pfam04023
755732003356	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
755732003357	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
755732003358	G1 box; other site
755732003359	GTP/Mg2+ binding site [chemical binding]; other site
755732003360	Switch I region; other site
755732003361	G2 box; other site
755732003362	G3 box; other site
755732003363	Switch II region; other site
755732003364	G4 box; other site
755732003365	G5 box; other site
755732003366	Nucleoside recognition; Region: Gate; pfam07670
755732003367	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
755732003368	Nucleoside recognition; Region: Gate; pfam07670
755732003369	LemA family; Region: LemA; cl00742
755732003370	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
755732003371	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
755732003372	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
755732003373	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
755732003374	RNA binding surface [nucleotide binding]; other site
755732003375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
755732003376	Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; cl01267
755732003377	SEC-C motif; Region: SEC-C; pfam02810
755732003378	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732003379	dimerization interface [polypeptide binding]; other site
755732003380	putative DNA binding site [nucleotide binding]; other site
755732003381	putative Zn2+ binding site [ion binding]; other site
755732003382	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
755732003383	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
755732003384	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
755732003385	Methyltransferase domain; Region: Methyltransf_23; pfam13489
755732003386	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732003387	S-adenosylmethionine binding site [chemical binding]; other site
755732003388	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
755732003389	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
755732003390	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
755732003391	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
755732003392	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
755732003393	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732003394	Colicin V production protein; Region: Colicin_V; pfam02674
755732003395	Tropomyosin like; Region: Tropomyosin_1; pfam12718
755732003396	Spectrin repeat; Region: Spectrin; pfam00435
755732003397	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
755732003398	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
755732003399	HIGH motif; other site
755732003400	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
755732003401	active site
755732003402	KMSKS motif; other site
755732003403	Dihydroneopterin aldolase; Region: FolB; pfam02152
755732003404	active site
755732003405	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732003406	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732003407	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732003408	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732003409	DNA binding residues [nucleotide binding]
755732003410	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732003411	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732003412	catalytic residues [active]
755732003413	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
755732003414	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
755732003415	Peptidase family M28; Region: Peptidase_M28; pfam04389
755732003416	metal binding site [ion binding]; metal-binding site
755732003417	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
755732003418	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732003419	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732003420	active site
755732003421	phosphorylation site [posttranslational modification]
755732003422	intermolecular recognition site; other site
755732003423	dimerization interface [polypeptide binding]; other site
755732003424	LytTr DNA-binding domain; Region: LytTR; smart00850
755732003425	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
755732003426	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
755732003427	active site
755732003428	catalytic residues [active]
755732003429	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003430	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732003431	Coenzyme A binding pocket [chemical binding]; other site
755732003432	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
755732003433	ribonuclease R; Region: RNase_R; TIGR02063
755732003434	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
755732003435	RNB domain; Region: RNB; pfam00773
755732003436	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
755732003437	RNA binding site [nucleotide binding]; other site
755732003438	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732003439	Walker A motif; other site
755732003440	ATP binding site [chemical binding]; other site
755732003441	Walker B motif; other site
755732003442	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
755732003443	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
755732003444	Ferritin-like domain; Region: Ferritin; pfam00210
755732003445	ferroxidase diiron center [ion binding]; other site
755732003446	Two component regulator propeller; Region: Reg_prop; pfam07494
755732003447	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732003448	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
755732003449	cyclase homology domain; Region: CHD; cd07302
755732003450	nucleotidyl binding site; other site
755732003451	metal binding site [ion binding]; metal-binding site
755732003452	dimer interface [polypeptide binding]; other site
755732003453	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
755732003454	Zn2+ binding site [ion binding]; other site
755732003455	Mg2+ binding site [ion binding]; other site
755732003456	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732003457	Ligand Binding Site [chemical binding]; other site
755732003458	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732003459	Ligand Binding Site [chemical binding]; other site
755732003460	GH3 auxin-responsive promoter; Region: GH3; pfam03321
755732003461	EamA-like transporter family; Region: EamA; pfam00892
755732003462	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
755732003463	EamA-like transporter family; Region: EamA; pfam00892
755732003464	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
755732003465	AMP binding site [chemical binding]; other site
755732003466	metal binding site [ion binding]; metal-binding site
755732003467	active site
755732003468	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732003469	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732003470	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732003471	DNA binding residues [nucleotide binding]
755732003472	Domain of unknown function (DUF4382); Region: DUF4382; pfam14321
755732003473	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
755732003474	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
755732003475	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732003476	ATP binding site [chemical binding]; other site
755732003477	putative Mg++ binding site [ion binding]; other site
755732003478	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732003479	nucleotide binding region [chemical binding]; other site
755732003480	ATP-binding site [chemical binding]; other site
755732003481	TRCF domain; Region: TRCF; pfam03461
755732003482	Fic family protein [Function unknown]; Region: COG3177
755732003483	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
755732003484	Fic/DOC family; Region: Fic; pfam02661
755732003485	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732003486	active site
755732003487	PKD domain; Region: PKD; pfam00801
755732003488	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003489	Penicillinase repressor; Region: Pencillinase_R; pfam03965
755732003490	Peptidase C1-like family; Region: Peptidase_C1_2; cl17447
755732003491	DNA protecting protein DprA; Region: dprA; TIGR00732
755732003492	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
755732003493	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
755732003494	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
755732003495	GIY-YIG motif/motif A; other site
755732003496	active site
755732003497	catalytic site [active]
755732003498	putative DNA binding site [nucleotide binding]; other site
755732003499	metal binding site [ion binding]; metal-binding site
755732003500	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
755732003501	Peptidase family M48; Region: Peptidase_M48; pfam01435
755732003502	Putative cyclase; Region: Cyclase; pfam04199
755732003503	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
755732003504	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732003505	dimerization interface [polypeptide binding]; other site
755732003506	putative DNA binding site [nucleotide binding]; other site
755732003507	putative Zn2+ binding site [ion binding]; other site
755732003508	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
755732003509	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
755732003510	substrate binding site [chemical binding]; other site
755732003511	oxyanion hole (OAH) forming residues; other site
755732003512	trimer interface [polypeptide binding]; other site
755732003513	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
755732003514	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732003515	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732003516	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732003517	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732003518	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003519	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003520	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732003521	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003522	Sporulation related domain; Region: SPOR; pfam05036
755732003523	DoxX-like family; Region: DoxX_2; pfam13564
755732003524	Predicted transcriptional regulators [Transcription]; Region: COG1733
755732003525	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
755732003526	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732003527	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732003528	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
755732003529	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003530	binding surface
755732003531	TPR motif; other site
755732003532	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
755732003533	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003534	binding surface
755732003535	TPR motif; other site
755732003536	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
755732003537	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
755732003538	Walker A/P-loop; other site
755732003539	ATP binding site [chemical binding]; other site
755732003540	Q-loop/lid; other site
755732003541	ABC transporter signature motif; other site
755732003542	Walker B; other site
755732003543	D-loop; other site
755732003544	H-loop/switch region; other site
755732003545	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
755732003546	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732003547	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732003548	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
755732003549	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732003550	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732003551	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003552	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732003553	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732003554	active site
755732003555	phosphorylation site [posttranslational modification]
755732003556	intermolecular recognition site; other site
755732003557	dimerization interface [polypeptide binding]; other site
755732003558	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732003559	DNA binding site [nucleotide binding]
755732003560	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
755732003561	catalytic motif [active]
755732003562	Zn binding site [ion binding]; other site
755732003563	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
755732003564	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732003565	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
755732003566	protein binding site [polypeptide binding]; other site
755732003567	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
755732003568	Catalytic dyad [active]
755732003569	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732003570	active site
755732003571	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003572	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003573	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
755732003574	FAD binding site [chemical binding]; other site
755732003575	TPR repeat; Region: TPR_11; pfam13414
755732003576	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003577	binding surface
755732003578	TPR motif; other site
755732003579	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
755732003580	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
755732003581	inhibitor-cofactor binding pocket; inhibition site
755732003582	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732003583	catalytic residue [active]
755732003584	kynureninase; Region: kynureninase; TIGR01814
755732003585	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
755732003586	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732003587	catalytic residue [active]
755732003588	FAD binding domain; Region: FAD_binding_3; pfam01494
755732003589	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732003590	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
755732003591	Predicted membrane protein [Function unknown]; Region: COG3463
755732003592	Predicted membrane protein (DUF2079); Region: DUF2079; pfam09852
755732003593	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732003594	ArsC family; Region: ArsC; pfam03960
755732003595	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
755732003596	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
755732003597	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
755732003598	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
755732003599	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
755732003600	Predicted membrane protein [Function unknown]; Region: COG1238
755732003601	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003602	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
755732003603	active site
755732003604	catalytic triad [active]
755732003605	dimer interface [polypeptide binding]; other site
755732003606	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003607	methionine aminotransferase; Validated; Region: PRK09082
755732003608	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
755732003609	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732003610	homodimer interface [polypeptide binding]; other site
755732003611	catalytic residue [active]
755732003612	glycine dehydrogenase; Provisional; Region: PRK05367
755732003613	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
755732003614	tetramer interface [polypeptide binding]; other site
755732003615	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732003616	catalytic residue [active]
755732003617	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
755732003618	tetramer interface [polypeptide binding]; other site
755732003619	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732003620	catalytic residue [active]
755732003621	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003622	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003623	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003624	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003625	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003626	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003627	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003628	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003629	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003630	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003631	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003632	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732003633	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732003634	active site
755732003635	phosphorylation site [posttranslational modification]
755732003636	intermolecular recognition site; other site
755732003637	dimerization interface [polypeptide binding]; other site
755732003638	LytTr DNA-binding domain; Region: LytTR; smart00850
755732003639	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732003640	binding surface
755732003641	TPR motif; other site
755732003642	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003643	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003644	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003645	binding surface
755732003646	TPR motif; other site
755732003647	Histidine kinase; Region: His_kinase; pfam06580
755732003648	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732003649	ATP binding site [chemical binding]; other site
755732003650	Mg2+ binding site [ion binding]; other site
755732003651	G-X-G motif; other site
755732003652	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732003653	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
755732003654	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
755732003655	catalytic residues [active]
755732003656	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732003657	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732003658	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003659	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
755732003660	Peptidase family M23; Region: Peptidase_M23; pfam01551
755732003661	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
755732003662	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003663	TPR motif; other site
755732003664	binding surface
755732003665	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732003666	binding surface
755732003667	TPR motif; other site
755732003668	TPR repeat; Region: TPR_11; pfam13414
755732003669	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003670	binding surface
755732003671	TPR motif; other site
755732003672	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732003673	TPR repeat; Region: TPR_11; pfam13414
755732003674	TPR motif; other site
755732003675	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
755732003676	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
755732003677	active site
755732003678	Substrate binding site; other site
755732003679	Mg++ binding site; other site
755732003680	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
755732003681	putative trimer interface [polypeptide binding]; other site
755732003682	putative CoA binding site [chemical binding]; other site
755732003683	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
755732003684	trimer interface [polypeptide binding]; other site
755732003685	active site
755732003686	GldH lipoprotein; Region: GldH_lipo; pfam14109
755732003687	PSP1 C-terminal conserved region; Region: PSP1; cl00770
755732003688	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
755732003689	DNA polymerase III subunit delta'; Validated; Region: PRK08485
755732003690	AAA domain; Region: AAA_13; pfam13166
755732003691	hypothetical protein; Provisional; Region: PRK11281
755732003692	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
755732003693	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003694	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
755732003695	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
755732003696	putative active site [active]
755732003697	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
755732003698	bifunctional phosphoglucose/phosphomannose isomerase; Validated; Region: PRK08674
755732003699	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
755732003700	The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to...; Region: SIS_PGI_PMI_2; cd05637
755732003701	dimer interface [polypeptide binding]; other site
755732003702	active site
755732003703	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732003704	TIGR01777 family protein; Region: yfcH
755732003705	NAD(P) binding site [chemical binding]; other site
755732003706	active site
755732003707	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
755732003708	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732003709	catalytic triad [active]
755732003710	recombinase A; Provisional; Region: recA; PRK09354
755732003711	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
755732003712	hexamer interface [polypeptide binding]; other site
755732003713	Walker A motif; other site
755732003714	ATP binding site [chemical binding]; other site
755732003715	Walker B motif; other site
755732003716	hypothetical protein; Provisional; Region: PRK11820
755732003717	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
755732003718	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
755732003719	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
755732003720	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
755732003721	catalytic site [active]
755732003722	G-X2-G-X-G-K; other site
755732003723	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
755732003724	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
755732003725	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
755732003726	active site
755732003727	(T/H)XGH motif; other site
755732003728	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
755732003729	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732003730	ATP binding site [chemical binding]; other site
755732003731	putative Mg++ binding site [ion binding]; other site
755732003732	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732003733	nucleotide binding region [chemical binding]; other site
755732003734	ATP-binding site [chemical binding]; other site
755732003735	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
755732003736	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
755732003737	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732003738	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732003739	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732003740	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
755732003741	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003742	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
755732003743	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
755732003744	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732003745	motif II; other site
755732003746	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
755732003747	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
755732003748	Imelysin; Region: Peptidase_M75; cl09159
755732003749	Predicted thiol oxidoreductase [Energy production and conversion]; Region: COG3488
755732003750	Protein of unknown function (DUF1111); Region: DUF1111; pfam06537
755732003751	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732003752	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732003753	ligand binding site [chemical binding]; other site
755732003754	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
755732003755	active site
755732003756	catalytic triad [active]
755732003757	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732003758	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732003759	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003760	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
755732003761	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
755732003762	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
755732003763	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732003764	Walker A/P-loop; other site
755732003765	ATP binding site [chemical binding]; other site
755732003766	Q-loop/lid; other site
755732003767	ABC transporter signature motif; other site
755732003768	Walker B; other site
755732003769	D-loop; other site
755732003770	H-loop/switch region; other site
755732003771	chaperone protein DnaJ; Provisional; Region: PRK14299
755732003772	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732003773	HSP70 interaction site [polypeptide binding]; other site
755732003774	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
755732003775	substrate binding site [polypeptide binding]; other site
755732003776	dimer interface [polypeptide binding]; other site
755732003777	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
755732003778	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
755732003779	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
755732003780	Int/Topo IB signature motif; other site
755732003781	RteC protein; Region: RteC; pfam09357
755732003782	Helix-turn-helix domain; Region: HTH_17; cl17695
755732003783	RNA helicase; Region: RNA_helicase; pfam00910
755732003784	Predicted transcriptional regulator [Transcription]; Region: COG2378
755732003785	WYL domain; Region: WYL; pfam13280
755732003786	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732003787	ATP binding site [chemical binding]; other site
755732003788	Mg2+ binding site [ion binding]; other site
755732003789	G-X-G motif; other site
755732003790	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
755732003791	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
755732003792	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
755732003793	HsdM N-terminal domain; Region: HsdM_N; pfam12161
755732003794	Methyltransferase domain; Region: Methyltransf_26; pfam13659
755732003795	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
755732003796	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
755732003797	Divergent AAA domain; Region: AAA_4; pfam04326
755732003798	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
755732003799	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
755732003800	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
755732003801	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
755732003802	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
755732003803	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
755732003804	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732003805	ATP binding site [chemical binding]; other site
755732003806	putative Mg++ binding site [ion binding]; other site
755732003807	nucleotide binding region [chemical binding]; other site
755732003808	helicase superfamily c-terminal domain; Region: HELICc; smart00490
755732003809	ATP-binding site [chemical binding]; other site
755732003810	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
755732003811	putative catalytic site [active]
755732003812	putative metal binding site [ion binding]; other site
755732003813	putative phosphate binding site [ion binding]; other site
755732003814	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
755732003815	active site
755732003816	homodimer interface [polypeptide binding]; other site
755732003817	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
755732003818	active site
755732003819	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
755732003820	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
755732003821	substrate binding site; other site
755732003822	dimer interface; other site
755732003823	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003824	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
755732003825	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
755732003826	Fatty acid desaturase; Region: FA_desaturase; pfam00487
755732003827	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
755732003828	putative di-iron ligands [ion binding]; other site
755732003829	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
755732003830	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
755732003831	putative active site [active]
755732003832	catalytic residue [active]
755732003833	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
755732003834	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
755732003835	Ligand binding site; other site
755732003836	oligomer interface; other site
755732003837	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
755732003838	lipoprotein signal peptidase; Provisional; Region: PRK14787
755732003839	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
755732003840	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
755732003841	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732003842	S-adenosylmethionine binding site [chemical binding]; other site
755732003843	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
755732003844	Protein metal binding site; Region: Cu-binding_MopE; pfam11617
755732003845	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003846	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
755732003847	Lumazine binding domain; Region: Lum_binding; pfam00677
755732003848	Lumazine binding domain; Region: Lum_binding; pfam00677
755732003849	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
755732003850	O-Antigen ligase; Region: Wzy_C; pfam04932
755732003851	Chain length determinant protein [Cell envelope biogenesis, outer membrane]; Region: WzzB; COG3765
755732003852	Chain length determinant protein; Region: Wzz; pfam02706
755732003853	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
755732003854	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
755732003855	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
755732003856	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
755732003857	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732003858	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
755732003859	GTP-binding protein LepA; Provisional; Region: PRK05433
755732003860	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
755732003861	G1 box; other site
755732003862	putative GEF interaction site [polypeptide binding]; other site
755732003863	GTP/Mg2+ binding site [chemical binding]; other site
755732003864	Switch I region; other site
755732003865	G2 box; other site
755732003866	G3 box; other site
755732003867	Switch II region; other site
755732003868	G4 box; other site
755732003869	G5 box; other site
755732003870	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
755732003871	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
755732003872	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
755732003873	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732003874	ligand binding site [chemical binding]; other site
755732003875	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732003876	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732003877	active site
755732003878	phosphorylation site [posttranslational modification]
755732003879	intermolecular recognition site; other site
755732003880	dimerization interface [polypeptide binding]; other site
755732003881	LytTr DNA-binding domain; Region: LytTR; smart00850
755732003882	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003883	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732003884	binding surface
755732003885	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003886	TPR motif; other site
755732003887	Histidine kinase; Region: His_kinase; pfam06580
755732003888	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732003889	ATP binding site [chemical binding]; other site
755732003890	Mg2+ binding site [ion binding]; other site
755732003891	G-X-G motif; other site
755732003892	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732003893	active site
755732003894	HIGH motif; other site
755732003895	nucleotide binding site [chemical binding]; other site
755732003896	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732003897	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
755732003898	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732003899	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732003900	active site
755732003901	KMSKS motif; other site
755732003902	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
755732003903	tRNA binding surface [nucleotide binding]; other site
755732003904	Anticodon-binding domain of tRNA; Region: Anticodon_1; pfam08264
755732003905	GxxExxY protein; Region: GxxExxY; TIGR04256
755732003906	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
755732003907	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
755732003908	dimerization interface [polypeptide binding]; other site
755732003909	DPS ferroxidase diiron center [ion binding]; other site
755732003910	ion pore; other site
755732003911	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
755732003912	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
755732003913	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003914	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003915	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003916	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003917	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003918	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732003919	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732003920	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732003921	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732003922	active site
755732003923	phosphorylation site [posttranslational modification]
755732003924	intermolecular recognition site; other site
755732003925	dimerization interface [polypeptide binding]; other site
755732003926	LytTr DNA-binding domain; Region: LytTR; smart00850
755732003927	Two component regulator propeller; Region: Reg_prop; pfam07494
755732003928	Histidine kinase; Region: His_kinase; pfam06580
755732003929	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732003930	Mg2+ binding site [ion binding]; other site
755732003931	G-X-G motif; other site
755732003932	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
755732003933	putative active site [active]
755732003934	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
755732003935	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732003936	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732003937	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
755732003938	PemK-like protein; Region: PemK; pfam02452
755732003939	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
755732003940	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732003941	putative substrate translocation pore; other site
755732003942	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
755732003943	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732003944	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732003945	Outer membrane efflux protein; Region: OEP; pfam02321
755732003946	Outer membrane efflux protein; Region: OEP; pfam02321
755732003947	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
755732003948	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
755732003949	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
755732003950	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
755732003951	dimer interface [polypeptide binding]; other site
755732003952	active site
755732003953	metal binding site [ion binding]; metal-binding site
755732003954	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
755732003955	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
755732003956	TPP-binding site; other site
755732003957	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
755732003958	PYR/PP interface [polypeptide binding]; other site
755732003959	dimer interface [polypeptide binding]; other site
755732003960	TPP binding site [chemical binding]; other site
755732003961	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
755732003962	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
755732003963	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
755732003964	Predicted permeases [General function prediction only]; Region: COG0679
755732003965	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
755732003966	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
755732003967	putative dimer interface [polypeptide binding]; other site
755732003968	putative anticodon binding site; other site
755732003969	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
755732003970	homodimer interface [polypeptide binding]; other site
755732003971	motif 1; other site
755732003972	motif 2; other site
755732003973	active site
755732003974	motif 3; other site
755732003975	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
755732003976	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
755732003977	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
755732003978	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
755732003979	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
755732003980	active site
755732003981	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cl00049
755732003982	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732003983	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG4935
755732003984	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732003985	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
755732003986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732003987	binding surface
755732003988	TPR motif; other site
755732003989	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003990	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003991	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732003992	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732003993	Histidine kinase; Region: HisKA_3; pfam07730
755732003994	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732003995	ATP binding site [chemical binding]; other site
755732003996	Mg2+ binding site [ion binding]; other site
755732003997	G-X-G motif; other site
755732003998	two component system sensor kinase SsrB; Provisional; Region: PRK15369
755732003999	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732004000	active site
755732004001	phosphorylation site [posttranslational modification]
755732004002	intermolecular recognition site; other site
755732004003	dimerization interface [polypeptide binding]; other site
755732004004	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732004005	DNA binding residues [nucleotide binding]
755732004006	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004007	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004008	Uncharacterized conserved protein [Function unknown]; Region: COG1432
755732004009	LabA_like proteins; Region: LabA_like; cd06167
755732004010	putative metal binding site [ion binding]; other site
755732004011	GTP-binding protein Der; Reviewed; Region: PRK00093
755732004012	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
755732004013	G1 box; other site
755732004014	GTP/Mg2+ binding site [chemical binding]; other site
755732004015	Switch I region; other site
755732004016	G2 box; other site
755732004017	Switch II region; other site
755732004018	G3 box; other site
755732004019	G4 box; other site
755732004020	G5 box; other site
755732004021	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
755732004022	G1 box; other site
755732004023	GTP/Mg2+ binding site [chemical binding]; other site
755732004024	Switch I region; other site
755732004025	G2 box; other site
755732004026	G3 box; other site
755732004027	Switch II region; other site
755732004028	G4 box; other site
755732004029	G5 box; other site
755732004030	GTPase Era; Reviewed; Region: era; PRK00089
755732004031	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
755732004032	G1 box; other site
755732004033	GTP/Mg2+ binding site [chemical binding]; other site
755732004034	Switch I region; other site
755732004035	G2 box; other site
755732004036	Switch II region; other site
755732004037	G3 box; other site
755732004038	G4 box; other site
755732004039	G5 box; other site
755732004040	KH domain; Region: KH_2; pfam07650
755732004041	yiaA/B two helix domain; Region: YiaAB; pfam05360
755732004042	yiaA/B two helix domain; Region: YiaAB; pfam05360
755732004043	Leucine rich repeat; Region: LRR_8; pfam13855
755732004044	Leucine rich repeat; Region: LRR_8; pfam13855
755732004045	Leucine rich repeat; Region: LRR_8; pfam13855
755732004046	Leucine rich repeat; Region: LRR_8; pfam13855
755732004047	Leucine rich repeat; Region: LRR_8; pfam13855
755732004048	Leucine rich repeat; Region: LRR_8; pfam13855
755732004049	Leucine rich repeat; Region: LRR_8; pfam13855
755732004050	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
755732004051	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732004052	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732004053	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732004054	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732004055	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732004056	DNA binding residues [nucleotide binding]
755732004057	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
755732004058	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
755732004059	TrkA-C domain; Region: TrkA_C; pfam02080
755732004060	TrkA-C domain; Region: TrkA_C; pfam02080
755732004061	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
755732004062	Protein of unknown function (DUF1295); Region: DUF1295; cl17837
755732004063	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
755732004064	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732004065	active site
755732004066	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
755732004067	dimer interface [polypeptide binding]; other site
755732004068	putative radical transfer pathway; other site
755732004069	diiron center [ion binding]; other site
755732004070	tyrosyl radical; other site
755732004071	ribonucleoside--diphosphate reductase large subunit; Region: PLN02437
755732004072	ATP cone domain; Region: ATP-cone; pfam03477
755732004073	Class I ribonucleotide reductase; Region: RNR_I; cd01679
755732004074	active site
755732004075	dimer interface [polypeptide binding]; other site
755732004076	catalytic residues [active]
755732004077	effector binding site; other site
755732004078	R2 peptide binding site; other site
755732004079	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
755732004080	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004081	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004082	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004083	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
755732004084	Peptidase family M1; Region: Peptidase_M1; pfam01433
755732004085	Zn binding site [ion binding]; other site
755732004086	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
755732004087	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
755732004088	carboxyltransferase (CT) interaction site; other site
755732004089	biotinylation site [posttranslational modification]; other site
755732004090	Outer membrane protein Omp28; Region: Omp28; pfam11551
755732004091	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
755732004092	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732004093	catalytic residues [active]
755732004094	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004095	NAD-dependent deacetylase; Provisional; Region: PRK00481
755732004096	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
755732004097	NAD+ binding site [chemical binding]; other site
755732004098	substrate binding site [chemical binding]; other site
755732004099	Zn binding site [ion binding]; other site
755732004100	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732004101	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004102	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
755732004103	Malic enzyme, N-terminal domain; Region: malic; pfam00390
755732004104	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
755732004105	putative NAD(P) binding site [chemical binding]; other site
755732004106	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
755732004107	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
755732004108	RuvA N terminal domain; Region: RuvA_N; pfam01330
755732004109	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
755732004110	cell surface protein SprA; Region: surface_SprA; TIGR04189
755732004111	Motility related/secretion protein; Region: SprA_N; pfam14349
755732004112	Motility related/secretion protein; Region: SprA_N; pfam14349
755732004113	Motility related/secretion protein; Region: SprA_N; pfam14349
755732004114	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732004115	Coenzyme A binding pocket [chemical binding]; other site
755732004116	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
755732004117	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
755732004118	putative active site [active]
755732004119	catalytic triad [active]
755732004120	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
755732004121	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
755732004122	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
755732004123	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
755732004124	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
755732004125	Domain of unknown function DUF21; Region: DUF21; pfam01595
755732004126	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
755732004127	Transporter associated domain; Region: CorC_HlyC; smart01091
755732004128	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
755732004129	active site
755732004130	catalytic residues [active]
755732004131	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004132	ribosome maturation protein RimP; Reviewed; Region: PRK00092
755732004133	Sm and related proteins; Region: Sm_like; cl00259
755732004134	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
755732004135	putative oligomer interface [polypeptide binding]; other site
755732004136	putative RNA binding site [nucleotide binding]; other site
755732004137	transcription termination factor NusA; Region: NusA; TIGR01953
755732004138	NusA N-terminal domain; Region: NusA_N; pfam08529
755732004139	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
755732004140	RNA binding site [nucleotide binding]; other site
755732004141	homodimer interface [polypeptide binding]; other site
755732004142	NusA-like KH domain; Region: KH_5; pfam13184
755732004143	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
755732004144	G-X-X-G motif; other site
755732004145	translation initiation factor IF-2; Region: IF-2; TIGR00487
755732004146	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
755732004147	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
755732004148	G1 box; other site
755732004149	putative GEF interaction site [polypeptide binding]; other site
755732004150	GTP/Mg2+ binding site [chemical binding]; other site
755732004151	Switch I region; other site
755732004152	G2 box; other site
755732004153	G3 box; other site
755732004154	Switch II region; other site
755732004155	G4 box; other site
755732004156	G5 box; other site
755732004157	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
755732004158	Translation-initiation factor 2; Region: IF-2; pfam11987
755732004159	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
755732004160	Domain of unknown function (DUF4395); Region: DUF4395; pfam14340
755732004161	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
755732004162	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
755732004163	dimer interface [polypeptide binding]; other site
755732004164	decamer (pentamer of dimers) interface [polypeptide binding]; other site
755732004165	catalytic triad [active]
755732004166	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004167	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
755732004168	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732004169	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732004170	ligand binding site [chemical binding]; other site
755732004171	flexible hinge region; other site
755732004172	Outer membrane efflux protein; Region: OEP; pfam02321
755732004173	Outer membrane efflux protein; Region: OEP; pfam02321
755732004174	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732004175	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732004176	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
755732004177	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
755732004178	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
755732004179	TM1410 hypothetical-related protein; Region: DUF297; cl00997
755732004180	TM1410 hypothetical-related protein; Region: DUF297; cl00997
755732004181	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732004182	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
755732004183	DKNYY family; Region: DKNYY; pfam13644
755732004184	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
755732004185	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732004186	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
755732004187	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
755732004188	NAD binding site [chemical binding]; other site
755732004189	homodimer interface [polypeptide binding]; other site
755732004190	active site
755732004191	substrate binding site [chemical binding]; other site
755732004192	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732004193	rod shape-determining protein MreC; Provisional; Region: PRK13922
755732004194	rod shape-determining protein MreC; Region: MreC; pfam04085
755732004195	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
755732004196	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
755732004197	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
755732004198	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
755732004199	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
755732004200	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
755732004201	Lamin Tail Domain; Region: LTD; pfam00932
755732004202	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
755732004203	CotH protein; Region: CotH; pfam08757
755732004204	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004205	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732004206	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
755732004207	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
755732004208	purine monophosphate binding site [chemical binding]; other site
755732004209	dimer interface [polypeptide binding]; other site
755732004210	putative catalytic residues [active]
755732004211	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
755732004212	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
755732004213	rod shape-determining protein MreB; Provisional; Region: PRK13927
755732004214	MreB and similar proteins; Region: MreB_like; cd10225
755732004215	nucleotide binding site [chemical binding]; other site
755732004216	Mg binding site [ion binding]; other site
755732004217	putative protofilament interaction site [polypeptide binding]; other site
755732004218	RodZ interaction site [polypeptide binding]; other site
755732004219	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
755732004220	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
755732004221	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
755732004222	active site
755732004223	substrate binding site [chemical binding]; other site
755732004224	cosubstrate binding site; other site
755732004225	catalytic site [active]
755732004226	acyl carrier protein; Provisional; Region: acpP; PRK00982
755732004227	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
755732004228	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
755732004229	dimer interface [polypeptide binding]; other site
755732004230	active site
755732004231	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
755732004232	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
755732004233	dimerization interface [polypeptide binding]; other site
755732004234	active site
755732004235	metal binding site [ion binding]; metal-binding site
755732004236	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
755732004237	dsRNA binding site [nucleotide binding]; other site
755732004238	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004239	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
755732004240	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
755732004241	domain interfaces; other site
755732004242	active site
755732004243	Bacterial Ig-like domain; Region: Big_5; pfam13205
755732004244	Lamin Tail Domain; Region: LTD; pfam00932
755732004245	Lamin Tail Domain; Region: LTD; pfam00932
755732004246	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
755732004247	helicase 45; Provisional; Region: PTZ00424
755732004248	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
755732004249	ATP binding site [chemical binding]; other site
755732004250	Mg++ binding site [ion binding]; other site
755732004251	motif III; other site
755732004252	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732004253	nucleotide binding region [chemical binding]; other site
755732004254	ATP-binding site [chemical binding]; other site
755732004255	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
755732004256	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
755732004257	Protein of unknown function (DUF420); Region: DUF420; pfam04238
755732004258	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
755732004259	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
755732004260	Cu(I) binding site [ion binding]; other site
755732004261	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732004262	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; pfam03626
755732004263	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
755732004264	Subunit I/III interface [polypeptide binding]; other site
755732004265	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
755732004266	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
755732004267	protoheme IX farnesyltransferase; Region: cyoE_ctaB; TIGR01473
755732004268	UbiA prenyltransferase family; Region: UbiA; pfam01040
755732004269	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
755732004270	active site
755732004271	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
755732004272	intersubunit interface [polypeptide binding]; other site
755732004273	active site
755732004274	catalytic residue [active]
755732004275	Aldehyde dehydrogenase family 16A1-like; Region: ALDH_F16; cd07111
755732004276	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
755732004277	NAD(P) binding site [chemical binding]; other site
755732004278	catalytic residues [active]
755732004279	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
755732004280	NAD(P) binding site [chemical binding]; other site
755732004281	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004282	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732004283	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732004284	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
755732004285	lipoyl attachment site [posttranslational modification]; other site
755732004286	peptide chain release factor 2; Validated; Region: prfB; PRK00578
755732004287	This domain is found in peptide chain release factors; Region: PCRF; smart00937
755732004288	RF-1 domain; Region: RF-1; pfam00472
755732004289	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732004290	ArsC family; Region: ArsC; pfam03960
755732004291	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
755732004292	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
755732004293	dimer interface [polypeptide binding]; other site
755732004294	active site
755732004295	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
755732004296	catalytic residues [active]
755732004297	substrate binding site [chemical binding]; other site
755732004298	DOMON-like domain of copper-dependent monooxygenases and related proteins; Region: DOMON_DOH; cd09631
755732004299	DOMON domain; Region: DOMON; pfam03351
755732004300	putative ligand binding site [chemical binding]; other site
755732004301	Bacterial Ig-like domain; Region: Big_5; pfam13205
755732004302	Bacterial Ig-like domain; Region: Big_5; pfam13205
755732004303	Bacterial Ig-like domain; Region: Big_5; pfam13205
755732004304	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
755732004305	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
755732004306	MoxR-like ATPases [General function prediction only]; Region: COG0714
755732004307	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732004308	Walker A motif; other site
755732004309	ATP binding site [chemical binding]; other site
755732004310	Walker B motif; other site
755732004311	arginine finger; other site
755732004312	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
755732004313	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
755732004314	metal ion-dependent adhesion site (MIDAS); other site
755732004315	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
755732004316	metal ion-dependent adhesion site (MIDAS); other site
755732004317	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
755732004318	metal ion-dependent adhesion site (MIDAS); other site
755732004319	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732004320	binding surface
755732004321	TPR motif; other site
755732004322	Oxygen tolerance; Region: BatD; pfam13584
755732004323	heme biosynthesis-associated TPR protein; Region: TPR_hemY_coli; TIGR00540
755732004324	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
755732004325	Fasciclin domain; Region: Fasciclin; pfam02469
755732004326	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
755732004327	active site
755732004328	PKD domain; Region: PKD; pfam00801
755732004329	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004330	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
755732004331	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
755732004332	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
755732004333	seryl-tRNA synthetase; Provisional; Region: PRK05431
755732004334	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
755732004335	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
755732004336	motif 1; other site
755732004337	dimer interface [polypeptide binding]; other site
755732004338	active site
755732004339	motif 2; other site
755732004340	motif 3; other site
755732004341	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732004342	binding surface
755732004343	TPR motif; other site
755732004344	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
755732004345	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
755732004346	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; pfam00329
755732004347	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
755732004348	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
755732004349	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
755732004350	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
755732004351	putative dimer interface [polypeptide binding]; other site
755732004352	[2Fe-2S] cluster binding site [ion binding]; other site
755732004353	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
755732004354	SLBB domain; Region: SLBB; pfam10531
755732004355	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
755732004356	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
755732004357	catalytic loop [active]
755732004358	iron binding site [ion binding]; other site
755732004359	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
755732004360	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
755732004361	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
755732004362	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
755732004363	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
755732004364	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
755732004365	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
755732004366	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
755732004367	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
755732004368	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
755732004369	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
755732004370	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
755732004371	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
755732004372	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00144
755732004373	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
755732004374	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
755732004375	Ligand binding site; other site
755732004376	Putative Catalytic site; other site
755732004377	DXD motif; other site
755732004378	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732004379	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732004380	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732004381	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732004382	NAD(P) binding site [chemical binding]; other site
755732004383	active site
755732004384	homogentisate 1,2-dioxygenase; Region: HgmA; cl17306
755732004385	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
755732004386	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
755732004387	dimer interface [polypeptide binding]; other site
755732004388	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
755732004389	active site
755732004390	Fe binding site [ion binding]; other site
755732004391	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732004392	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732004393	Lipoate-protein ligase B [Coenzyme metabolism]; Region: LipB; COG0321
755732004394	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
755732004395	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
755732004396	active site
755732004397	oxyanion hole [active]
755732004398	catalytic triad [active]
755732004399	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
755732004400	active site
755732004401	oxyanion hole [active]
755732004402	catalytic triad [active]
755732004403	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
755732004404	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
755732004405	catalytic residues [active]
755732004406	methionine sulfoxide reductase A; Provisional; Region: PRK14054
755732004407	SurA N-terminal domain; Region: SurA_N_3; cl07813
755732004408	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
755732004409	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732004410	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cl00218
755732004411	active site
755732004412	catalytic residues [active]
755732004413	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cl00218
755732004414	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004415	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
755732004416	active site
755732004417	catalytic residues [active]
755732004418	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
755732004419	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
755732004420	active site
755732004421	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732004422	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
755732004423	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
755732004424	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732004425	active site residue [active]
755732004426	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732004427	active site residue [active]
755732004428	Keratin; Region: Keratin; pfam02422
755732004429	glycyl-tRNA synthetase; Provisional; Region: PRK04173
755732004430	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
755732004431	motif 1; other site
755732004432	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
755732004433	motif 1; other site
755732004434	dimer interface [polypeptide binding]; other site
755732004435	active site
755732004436	motif 2; other site
755732004437	motif 3; other site
755732004438	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
755732004439	anticodon binding site; other site
755732004440	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732004441	Histidine kinase; Region: HisKA_3; pfam07730
755732004442	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732004443	ATP binding site [chemical binding]; other site
755732004444	Mg2+ binding site [ion binding]; other site
755732004445	G-X-G motif; other site
755732004446	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732004447	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732004448	intermolecular recognition site; other site
755732004449	active site
755732004450	dimerization interface [polypeptide binding]; other site
755732004451	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
755732004452	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732004453	DNA binding residues [nucleotide binding]
755732004454	dimerization interface [polypeptide binding]; other site
755732004455	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
755732004456	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
755732004457	active site
755732004458	catalytic residues [active]
755732004459	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
755732004460	Late embryogenesis abundant protein; Region: LEA_2; pfam03168
755732004461	hypothetical protein; Provisional; Region: PRK08201
755732004462	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
755732004463	metal binding site [ion binding]; metal-binding site
755732004464	putative dimer interface [polypeptide binding]; other site
755732004465	Calx-beta domain; Region: Calx-beta; cl02522
755732004466	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004467	phosphoglyceromutase; Provisional; Region: PRK05434
755732004468	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
755732004469	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732004470	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732004471	dimer interface [polypeptide binding]; other site
755732004472	phosphorylation site [posttranslational modification]
755732004473	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732004474	ATP binding site [chemical binding]; other site
755732004475	Mg2+ binding site [ion binding]; other site
755732004476	G-X-G motif; other site
755732004477	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
755732004478	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
755732004479	active site
755732004480	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004481	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732004482	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
755732004483	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
755732004484	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732004485	FeS/SAM binding site; other site
755732004486	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
755732004487	active site
755732004488	catalytic motif [active]
755732004489	Zn binding site [ion binding]; other site
755732004490	membrane ATPase/protein kinase; Provisional; Region: PRK09435
755732004491	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
755732004492	Walker A; other site
755732004493	S4 domain; Region: S4_2; pfam13275
755732004494	3-hydroxyanthranilic acid dioxygenase; Region: 3-HAO; cl17399
755732004495	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004496	short chain dehydrogenase; Provisional; Region: PRK08339
755732004497	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
755732004498	putative NAD(P) binding site [chemical binding]; other site
755732004499	putative active site [active]
755732004500	Calx-beta domain; Region: Calx-beta; cl02522
755732004501	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004502	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004503	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
755732004504	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
755732004505	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
755732004506	Walker A/P-loop; other site
755732004507	ATP binding site [chemical binding]; other site
755732004508	Q-loop/lid; other site
755732004509	ABC transporter signature motif; other site
755732004510	Walker B; other site
755732004511	D-loop; other site
755732004512	H-loop/switch region; other site
755732004513	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
755732004514	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
755732004515	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
755732004516	PAS domain; Region: PAS_9; pfam13426
755732004517	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
755732004518	putative active site [active]
755732004519	heme pocket [chemical binding]; other site
755732004520	PAS domain S-box; Region: sensory_box; TIGR00229
755732004521	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
755732004522	putative active site [active]
755732004523	heme pocket [chemical binding]; other site
755732004524	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732004525	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
755732004526	ATP-grasp domain; Region: ATP-grasp; pfam02222
755732004527	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732004528	active site
755732004529	adenylate kinase; Reviewed; Region: adk; PRK00279
755732004530	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
755732004531	AMP-binding site [chemical binding]; other site
755732004532	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
755732004533	GTPase CgtA; Reviewed; Region: obgE; PRK12299
755732004534	GTP1/OBG; Region: GTP1_OBG; pfam01018
755732004535	Obg GTPase; Region: Obg; cd01898
755732004536	G1 box; other site
755732004537	GTP/Mg2+ binding site [chemical binding]; other site
755732004538	Switch I region; other site
755732004539	G2 box; other site
755732004540	G3 box; other site
755732004541	Switch II region; other site
755732004542	G4 box; other site
755732004543	G5 box; other site
755732004544	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
755732004545	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
755732004546	active site
755732004547	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
755732004548	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732004549	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
755732004550	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
755732004551	putative acyl-acceptor binding pocket; other site
755732004552	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
755732004553	HYR domain; Region: HYR; pfam02494
755732004554	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
755732004555	HYR domain; Region: HYR; pfam02494
755732004556	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004557	AIR carboxylase; Region: AIRC; pfam00731
755732004558	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004559	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
755732004560	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
755732004561	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
755732004562	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
755732004563	FtsX-like permease family; Region: FtsX; pfam02687
755732004564	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
755732004565	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
755732004566	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
755732004567	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004568	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
755732004569	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732004570	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732004571	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732004572	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732004573	ligand binding site [chemical binding]; other site
755732004574	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004575	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
755732004576	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
755732004577	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
755732004578	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
755732004579	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
755732004580	N-acetyl-D-glucosamine binding site [chemical binding]; other site
755732004581	catalytic residue [active]
755732004582	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
755732004583	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
755732004584	Mg++ binding site [ion binding]; other site
755732004585	putative catalytic motif [active]
755732004586	substrate binding site [chemical binding]; other site
755732004587	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
755732004588	Chain length determinant protein; Region: Wzz; pfam02706
755732004589	tyrosine kinase; Provisional; Region: PRK11519
755732004590	Arabidopsis broad-spectrum mildew resistance protein RPW8; Region: RPW8; pfam05659
755732004591	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
755732004592	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
755732004593	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
755732004594	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
755732004595	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732004596	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
755732004597	putative ADP-binding pocket [chemical binding]; other site
755732004598	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
755732004599	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
755732004600	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
755732004601	inhibitor-cofactor binding pocket; inhibition site
755732004602	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732004603	catalytic residue [active]
755732004604	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
755732004605	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
755732004606	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
755732004607	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
755732004608	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
755732004609	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
755732004610	NAD binding site [chemical binding]; other site
755732004611	putative substrate binding site 2 [chemical binding]; other site
755732004612	putative substrate binding site 1 [chemical binding]; other site
755732004613	active site
755732004614	putative trimer interface [polypeptide binding]; other site
755732004615	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
755732004616	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
755732004617	putative trimer interface [polypeptide binding]; other site
755732004618	putative active site [active]
755732004619	putative substrate binding site [chemical binding]; other site
755732004620	putative CoA binding site [chemical binding]; other site
755732004621	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
755732004622	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
755732004623	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
755732004624	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
755732004625	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
755732004626	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
755732004627	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
755732004628	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004629	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732004630	legume lectins; Region: lectin_L-type; cl14058
755732004631	carbohydrate binding site [chemical binding]; other site
755732004632	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004633	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004634	legume lectins; Region: lectin_L-type; cl14058
755732004635	homotetramer interaction site [polypeptide binding]; other site
755732004636	carbohydrate binding site [chemical binding]; other site
755732004637	metal binding site [ion binding]; metal-binding site
755732004638	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004639	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004640	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004641	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732004642	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732004643	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732004644	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732004645	binding surface
755732004646	TPR motif; other site
755732004647	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732004648	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
755732004649	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
755732004650	NAD binding site [chemical binding]; other site
755732004651	substrate binding site [chemical binding]; other site
755732004652	homodimer interface [polypeptide binding]; other site
755732004653	active site
755732004654	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
755732004655	YceI-like domain; Region: YceI; pfam04264
755732004656	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732004657	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
755732004658	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
755732004659	dimer interface [polypeptide binding]; other site
755732004660	active site
755732004661	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
755732004662	Fe-S metabolism associated domain; Region: SufE; cl00951
755732004663	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
755732004664	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
755732004665	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732004666	catalytic residue [active]
755732004667	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732004668	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732004669	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732004670	DNA binding residues [nucleotide binding]
755732004671	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
755732004672	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
755732004673	RNA binding surface [nucleotide binding]; other site
755732004674	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
755732004675	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732004676	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004677	FeS assembly protein SufD; Region: sufD; TIGR01981
755732004678	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
755732004679	FeS assembly ATPase SufC; Region: sufC; TIGR01978
755732004680	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
755732004681	Walker A/P-loop; other site
755732004682	ATP binding site [chemical binding]; other site
755732004683	Q-loop/lid; other site
755732004684	ABC transporter signature motif; other site
755732004685	Walker B; other site
755732004686	D-loop; other site
755732004687	H-loop/switch region; other site
755732004688	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
755732004689	putative ABC transporter; Region: ycf24; CHL00085
755732004690	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
755732004691	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732004692	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732004693	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732004694	Calx-beta domain; Region: Calx-beta; cl02522
755732004695	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732004696	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
755732004697	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
755732004698	active site
755732004699	Riboflavin kinase; Region: Flavokinase; pfam01687
755732004700	Leucine rich repeat; Region: LRR_8; pfam13855
755732004701	Leucine rich repeat; Region: LRR_8; pfam13855
755732004702	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
755732004703	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
755732004704	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732004705	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
755732004706	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
755732004707	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004708	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
755732004709	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
755732004710	active site
755732004711	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732004712	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732004713	ligand binding site [chemical binding]; other site
755732004714	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
755732004715	dimerization interface [polypeptide binding]; other site
755732004716	ATP binding site [chemical binding]; other site
755732004717	peptide chain release factor 1; Validated; Region: prfA; PRK00591
755732004718	PCRF domain; Region: PCRF; pfam03462
755732004719	RF-1 domain; Region: RF-1; pfam00472
755732004720	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732004721	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732004722	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732004723	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
755732004724	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
755732004725	active site
755732004726	dimer interface [polypeptide binding]; other site
755732004727	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
755732004728	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
755732004729	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
755732004730	intersubunit interface [polypeptide binding]; other site
755732004731	active site
755732004732	Zn2+ binding site [ion binding]; other site
755732004733	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
755732004734	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004735	Pirin-related protein [General function prediction only]; Region: COG1741
755732004736	Pirin; Region: Pirin; pfam02678
755732004737	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
755732004738	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732004739	ligand binding site [chemical binding]; other site
755732004740	Surface antigen; Region: Bac_surface_Ag; pfam01103
755732004741	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
755732004742	Cupin domain; Region: Cupin_2; cl17218
755732004743	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
755732004744	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732004745	motif I; other site
755732004746	motif II; other site
755732004747	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
755732004748	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
755732004749	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732004750	Sulfatase; Region: Sulfatase; cl17466
755732004751	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
755732004752	active site
755732004753	Int/Topo IB signature motif; other site
755732004754	DNA binding site [nucleotide binding]
755732004755	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732004756	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
755732004757	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732004758	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732004759	non-specific DNA binding site [nucleotide binding]; other site
755732004760	salt bridge; other site
755732004761	sequence-specific DNA binding site [nucleotide binding]; other site
755732004762	Superfamily II helicase [General function prediction only]; Region: COG1204
755732004763	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
755732004764	ATP binding site [chemical binding]; other site
755732004765	putative Mg++ binding site [ion binding]; other site
755732004766	helicase superfamily c-terminal domain; Region: HELICc; smart00490
755732004767	Protein of unknown function (DUF4238); Region: DUF4238; pfam14022
755732004768	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
755732004769	active site
755732004770	catalytic triad [active]
755732004771	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
755732004772	putative active site [active]
755732004773	putative NTP binding site [chemical binding]; other site
755732004774	putative nucleic acid binding site [nucleotide binding]; other site
755732004775	CHC2 zinc finger; Region: zf-CHC2; cl17510
755732004776	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
755732004777	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
755732004778	active site
755732004779	metal binding site [ion binding]; metal-binding site
755732004780	interdomain interaction site; other site
755732004781	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
755732004782	PspC domain; Region: PspC; cl00864
755732004783	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
755732004784	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
755732004785	NADP binding site [chemical binding]; other site
755732004786	active site
755732004787	putative substrate binding site [chemical binding]; other site
755732004788	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
755732004789	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
755732004790	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732004791	active site
755732004792	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
755732004793	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
755732004794	active site
755732004795	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
755732004796	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
755732004797	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
755732004798	active site
755732004799	DNA binding site [nucleotide binding]
755732004800	Int/Topo IB signature motif; other site
755732004801	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
755732004802	30S subunit binding site; other site
755732004803	elongation factor Tu; Reviewed; Region: PRK12735
755732004804	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
755732004805	G1 box; other site
755732004806	GEF interaction site [polypeptide binding]; other site
755732004807	GTP/Mg2+ binding site [chemical binding]; other site
755732004808	Switch I region; other site
755732004809	G2 box; other site
755732004810	G3 box; other site
755732004811	Switch II region; other site
755732004812	G4 box; other site
755732004813	G5 box; other site
755732004814	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
755732004815	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
755732004816	Antibiotic Binding Site [chemical binding]; other site
755732004817	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
755732004818	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
755732004819	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
755732004820	putative homodimer interface [polypeptide binding]; other site
755732004821	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
755732004822	heterodimer interface [polypeptide binding]; other site
755732004823	homodimer interface [polypeptide binding]; other site
755732004824	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
755732004825	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
755732004826	23S rRNA interface [nucleotide binding]; other site
755732004827	L7/L12 interface [polypeptide binding]; other site
755732004828	putative thiostrepton binding site; other site
755732004829	L25 interface [polypeptide binding]; other site
755732004830	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
755732004831	mRNA/rRNA interface [nucleotide binding]; other site
755732004832	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
755732004833	23S rRNA interface [nucleotide binding]; other site
755732004834	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
755732004835	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
755732004836	core dimer interface [polypeptide binding]; other site
755732004837	peripheral dimer interface [polypeptide binding]; other site
755732004838	L10 interface [polypeptide binding]; other site
755732004839	L11 interface [polypeptide binding]; other site
755732004840	putative EF-Tu interaction site [polypeptide binding]; other site
755732004841	putative EF-G interaction site [polypeptide binding]; other site
755732004842	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
755732004843	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
755732004844	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
755732004845	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
755732004846	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
755732004847	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
755732004848	RPB3 interaction site [polypeptide binding]; other site
755732004849	RPB1 interaction site [polypeptide binding]; other site
755732004850	RPB11 interaction site [polypeptide binding]; other site
755732004851	RPB10 interaction site [polypeptide binding]; other site
755732004852	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
755732004853	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
755732004854	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
755732004855	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
755732004856	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
755732004857	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
755732004858	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
755732004859	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
755732004860	DNA binding site [nucleotide binding]
755732004861	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
755732004862	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004863	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
755732004864	EamA-like transporter family; Region: EamA; pfam00892
755732004865	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
755732004866	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
755732004867	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732004868	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
755732004869	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
755732004870	Probable Catalytic site; other site
755732004871	metal-binding site
755732004872	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732004873	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
755732004874	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732004875	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732004876	Cell division protein ZapA; Region: ZapA; pfam05164
755732004877	phosphodiesterase; Provisional; Region: PRK12704
755732004878	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
755732004879	Zn2+ binding site [ion binding]; other site
755732004880	Mg2+ binding site [ion binding]; other site
755732004881	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
755732004882	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732004883	NAD(P) binding site [chemical binding]; other site
755732004884	active site
755732004885	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
755732004886	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
755732004887	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
755732004888	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
755732004889	O-Antigen ligase; Region: Wzy_C; pfam04932
755732004890	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
755732004891	ligand binding site; other site
755732004892	tetramer interface; other site
755732004893	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
755732004894	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
755732004895	NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_2; cd06426
755732004896	Substrate binding site; other site
755732004897	metal-binding site
755732004898	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
755732004899	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
755732004900	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
755732004901	active site
755732004902	homodimer interface [polypeptide binding]; other site
755732004903	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
755732004904	NeuB family; Region: NeuB; pfam03102
755732004905	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
755732004906	NeuB binding interface [polypeptide binding]; other site
755732004907	putative substrate binding site [chemical binding]; other site
755732004908	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
755732004909	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
755732004910	inhibitor-cofactor binding pocket; inhibition site
755732004911	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732004912	catalytic residue [active]
755732004913	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
755732004914	NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family; Region: EDH_00030; TIGR04180
755732004915	NAD binding site [chemical binding]; other site
755732004916	substrate binding site [chemical binding]; other site
755732004917	active site
755732004918	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
755732004919	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
755732004920	putative active site [active]
755732004921	oxyanion strand; other site
755732004922	catalytic triad [active]
755732004923	imidazole glycerol phosphate synthase subunit HisF; Provisional; Region: PRK01033
755732004924	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
755732004925	substrate binding site [chemical binding]; other site
755732004926	glutamase interaction surface [polypeptide binding]; other site
755732004927	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
755732004928	active site
755732004929	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
755732004930	homodimer interface [polypeptide binding]; other site
755732004931	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
755732004932	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
755732004933	putative trimer interface [polypeptide binding]; other site
755732004934	putative CoA binding site [chemical binding]; other site
755732004935	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
755732004936	ExoA is involved in the biosynthesis of succinoglycan; Region: Succinoglycan_BP_ExoA; cd02525
755732004937	Ligand binding site; other site
755732004938	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
755732004939	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
755732004940	inhibitor-cofactor binding pocket; inhibition site
755732004941	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732004942	catalytic residue [active]
755732004943	Bacterial sugar transferase; Region: Bac_transf; pfam02397
755732004944	Protein of unknown function, DUF486; Region: DUF486; cl01236
755732004945	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732004946	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
755732004947	DNA binding site [nucleotide binding]
755732004948	active site
755732004949	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732004950	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
755732004951	NAD(P) binding site [chemical binding]; other site
755732004952	active site
755732004953	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
755732004954	G1 box; other site
755732004955	GTP/Mg2+ binding site [chemical binding]; other site
755732004956	Switch I region; other site
755732004957	G2 box; other site
755732004958	G3 box; other site
755732004959	Switch II region; other site
755732004960	G4 box; other site
755732004961	G5 box; other site
755732004962	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
755732004963	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
755732004964	active site
755732004965	cell division protein MraZ; Reviewed; Region: PRK00326
755732004966	MraZ protein; Region: MraZ; pfam02381
755732004967	MraZ protein; Region: MraZ; pfam02381
755732004968	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
755732004969	MraW methylase family; Region: Methyltransf_5; cl17771
755732004970	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
755732004971	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
755732004972	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
755732004973	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
755732004974	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
755732004975	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
755732004976	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732004977	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
755732004978	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
755732004979	Mg++ binding site [ion binding]; other site
755732004980	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
755732004981	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
755732004982	putative catalytic motif [active]
755732004983	putative substrate binding site [chemical binding]; other site
755732004984	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
755732004985	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
755732004986	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732004987	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
755732004988	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
755732004989	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
755732004990	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
755732004991	active site
755732004992	homodimer interface [polypeptide binding]; other site
755732004993	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
755732004994	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
755732004995	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732004996	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
755732004997	Bacterial Ig-like domain; Region: Big_5; pfam13205
755732004998	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732004999	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732005000	active site
755732005001	phosphorylation site [posttranslational modification]
755732005002	intermolecular recognition site; other site
755732005003	dimerization interface [polypeptide binding]; other site
755732005004	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
755732005005	DNA binding residues [nucleotide binding]
755732005006	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732005007	Histidine kinase; Region: HisKA_3; pfam07730
755732005008	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732005009	ATP binding site [chemical binding]; other site
755732005010	Mg2+ binding site [ion binding]; other site
755732005011	G-X-G motif; other site
755732005012	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
755732005013	Cell division protein FtsA; Region: FtsA; smart00842
755732005014	Cell division protein FtsA; Region: FtsA; pfam14450
755732005015	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
755732005016	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
755732005017	nucleotide binding site [chemical binding]; other site
755732005018	SulA interaction site; other site
755732005019	Yqey-like protein; Region: YqeY; pfam09424
755732005020	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
755732005021	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
755732005022	Bacterial transcriptional repressor; Region: TetR; pfam13972
755732005023	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
755732005024	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
755732005025	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
755732005026	homotetramer interface [polypeptide binding]; other site
755732005027	ligand binding site [chemical binding]; other site
755732005028	catalytic site [active]
755732005029	NAD binding site [chemical binding]; other site
755732005030	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
755732005031	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
755732005032	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
755732005033	Alg9-like mannosyltransferase family; Region: Glyco_transf_22; cl17751
755732005034	NMT1/THI5 like; Region: NMT1; pfam09084
755732005035	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
755732005036	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
755732005037	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
755732005038	Walker A/P-loop; other site
755732005039	ATP binding site [chemical binding]; other site
755732005040	Q-loop/lid; other site
755732005041	ABC transporter signature motif; other site
755732005042	Walker B; other site
755732005043	D-loop; other site
755732005044	H-loop/switch region; other site
755732005045	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732005046	active site
755732005047	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
755732005048	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732005049	motif II; other site
755732005050	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
755732005051	DEAD-like helicases superfamily; Region: DEXDc; smart00487
755732005052	ATP binding site [chemical binding]; other site
755732005053	Mg++ binding site [ion binding]; other site
755732005054	motif III; other site
755732005055	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732005056	nucleotide binding region [chemical binding]; other site
755732005057	ATP-binding site [chemical binding]; other site
755732005058	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732005059	HSP70 interaction site [polypeptide binding]; other site
755732005060	KTSC domain; Region: KTSC; pfam13619
755732005061	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
755732005062	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
755732005063	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732005064	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732005065	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
755732005066	NAD(P) binding site [chemical binding]; other site
755732005067	active site
755732005068	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
755732005069	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
755732005070	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
755732005071	OsmC-like protein; Region: OsmC; pfam02566
755732005072	lipoyl synthase; Provisional; Region: PRK05481
755732005073	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732005074	FeS/SAM binding site; other site
755732005075	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
755732005076	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
755732005077	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
755732005078	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
755732005079	ferrochelatase; Reviewed; Region: hemH; PRK00035
755732005080	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
755732005081	C-terminal domain interface [polypeptide binding]; other site
755732005082	active site
755732005083	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
755732005084	active site
755732005085	N-terminal domain interface [polypeptide binding]; other site
755732005086	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
755732005087	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
755732005088	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732005089	ZIP Zinc transporter; Region: Zip; pfam02535
755732005090	Methyltransferase domain; Region: Methyltransf_31; pfam13847
755732005091	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732005092	S-adenosylmethionine binding site [chemical binding]; other site
755732005093	Domain of unknown function (DUF1987); Region: DUF1987; pfam09345
755732005094	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
755732005095	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
755732005096	CoA-binding site [chemical binding]; other site
755732005097	Peptidase S46; Region: Peptidase_S46; pfam10459
755732005098	gliding motility-associated protein GldC; Region: GldC; TIGR03515
755732005099	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
755732005100	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732005101	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
755732005102	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
755732005103	homodimer interface [polypeptide binding]; other site
755732005104	NAD binding pocket [chemical binding]; other site
755732005105	ATP binding pocket [chemical binding]; other site
755732005106	Mg binding site [ion binding]; other site
755732005107	active-site loop [active]
755732005108	Peptidase family M48; Region: Peptidase_M48; cl12018
755732005109	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
755732005110	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
755732005111	catalytic loop [active]
755732005112	iron binding site [ion binding]; other site
755732005113	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
755732005114	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
755732005115	ring oligomerisation interface [polypeptide binding]; other site
755732005116	ATP/Mg binding site [chemical binding]; other site
755732005117	stacking interactions; other site
755732005118	hinge regions; other site
755732005119	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
755732005120	oligomerisation interface [polypeptide binding]; other site
755732005121	mobile loop; other site
755732005122	roof hairpin; other site
755732005123	Preprotein translocase SecG subunit; Region: SecG; pfam03840
755732005124	Lipopolysaccharide-assembly; Region: LptE; pfam04390
755732005125	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732005126	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
755732005127	Walker A motif; other site
755732005128	ATP binding site [chemical binding]; other site
755732005129	Walker B motif; other site
755732005130	arginine finger; other site
755732005131	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
755732005132	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
755732005133	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
755732005134	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732005135	FeS/SAM binding site; other site
755732005136	TRAM domain; Region: TRAM; pfam01938
755732005137	DNA topoisomerase I; Validated; Region: PRK06599
755732005138	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
755732005139	active site
755732005140	interdomain interaction site; other site
755732005141	putative metal-binding site [ion binding]; other site
755732005142	nucleotide binding site [chemical binding]; other site
755732005143	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
755732005144	domain I; other site
755732005145	DNA binding groove [nucleotide binding]
755732005146	phosphate binding site [ion binding]; other site
755732005147	domain II; other site
755732005148	domain III; other site
755732005149	nucleotide binding site [chemical binding]; other site
755732005150	catalytic site [active]
755732005151	domain IV; other site
755732005152	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
755732005153	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
755732005154	putative active site [active]
755732005155	putative metal binding site [ion binding]; other site
755732005156	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
755732005157	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
755732005158	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
755732005159	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
755732005160	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
755732005161	GldM C-terminal domain; Region: GldM_C; pfam12080
755732005162	gliding motility associated protien GldN; Region: GldN; TIGR03523
755732005163	gliding motility associated protien GldN; Region: GldN; TIGR03523
755732005164	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
755732005165	GldM C-terminal domain; Region: GldM_C; pfam12080
755732005166	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
755732005167	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732005168	Walker A/P-loop; other site
755732005169	ATP binding site [chemical binding]; other site
755732005170	Q-loop/lid; other site
755732005171	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732005172	ABC transporter signature motif; other site
755732005173	Walker B; other site
755732005174	D-loop; other site
755732005175	ABC transporter; Region: ABC_tran_2; pfam12848
755732005176	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732005177	Protein of unknown function (DUF2797); Region: DUF2797; pfam10977
755732005178	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732005179	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732005180	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732005181	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732005182	non-specific DNA binding site [nucleotide binding]; other site
755732005183	salt bridge; other site
755732005184	sequence-specific DNA binding site [nucleotide binding]; other site
755732005185	Clp protease; Region: CLP_protease; pfam00574
755732005186	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
755732005187	oligomer interface [polypeptide binding]; other site
755732005188	active site residues [active]
755732005189	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
755732005190	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
755732005191	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732005192	Walker A motif; other site
755732005193	ATP binding site [chemical binding]; other site
755732005194	Walker B motif; other site
755732005195	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
755732005196	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732005197	S-adenosylmethionine binding site [chemical binding]; other site
755732005198	K+ potassium transporter; Region: K_trans; pfam02705
755732005199	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
755732005200	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
755732005201	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732005202	dimer interface [polypeptide binding]; other site
755732005203	phosphorylation site [posttranslational modification]
755732005204	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732005205	ATP binding site [chemical binding]; other site
755732005206	Mg2+ binding site [ion binding]; other site
755732005207	G-X-G motif; other site
755732005208	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732005209	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732005210	active site
755732005211	phosphorylation site [posttranslational modification]
755732005212	intermolecular recognition site; other site
755732005213	dimerization interface [polypeptide binding]; other site
755732005214	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732005215	DNA binding site [nucleotide binding]
755732005216	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
755732005217	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
755732005218	dimerization interface 3.5A [polypeptide binding]; other site
755732005219	active site
755732005220	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732005221	Histidine kinase; Region: His_kinase; pfam06580
755732005222	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732005223	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
755732005224	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
755732005225	active site
755732005226	HIGH motif; other site
755732005227	dimer interface [polypeptide binding]; other site
755732005228	KMSKS motif; other site
755732005229	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005230	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
755732005231	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
755732005232	amphipathic channel; other site
755732005233	Asn-Pro-Ala signature motifs; other site
755732005234	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
755732005235	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
755732005236	Walker A/P-loop; other site
755732005237	ATP binding site [chemical binding]; other site
755732005238	Q-loop/lid; other site
755732005239	ABC transporter signature motif; other site
755732005240	Walker B; other site
755732005241	D-loop; other site
755732005242	H-loop/switch region; other site
755732005243	GTPase RsgA; Reviewed; Region: PRK00098
755732005244	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
755732005245	RNA binding site [nucleotide binding]; other site
755732005246	homodimer interface [polypeptide binding]; other site
755732005247	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
755732005248	GTPase/Zn-binding domain interface [polypeptide binding]; other site
755732005249	GTP/Mg2+ binding site [chemical binding]; other site
755732005250	G4 box; other site
755732005251	G5 box; other site
755732005252	G1 box; other site
755732005253	Switch I region; other site
755732005254	G2 box; other site
755732005255	G3 box; other site
755732005256	Switch II region; other site
755732005257	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
755732005258	putative active site [active]
755732005259	dimerization interface [polypeptide binding]; other site
755732005260	putative tRNAtyr binding site [nucleotide binding]; other site
755732005261	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
755732005262	homodimer interface [polypeptide binding]; other site
755732005263	metal binding site [ion binding]; metal-binding site
755732005264	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
755732005265	active site flap/lid [active]
755732005266	nucleophilic elbow; other site
755732005267	catalytic triad [active]
755732005268	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
755732005269	nudix motif; other site
755732005270	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs; Region: NTP-PPase_DR2231_like; cd11530
755732005271	metal binding site [ion binding]; metal-binding site
755732005272	Transposase IS200 like; Region: Y1_Tnp; cl00848
755732005273	Phosphate transporter family; Region: PHO4; pfam01384
755732005274	Phosphate transporter family; Region: PHO4; pfam01384
755732005275	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
755732005276	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732005277	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732005278	active site
755732005279	phosphorylation site [posttranslational modification]
755732005280	intermolecular recognition site; other site
755732005281	dimerization interface [polypeptide binding]; other site
755732005282	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732005283	DNA binding site [nucleotide binding]
755732005284	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732005285	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732005286	active site
755732005287	phosphorylation site [posttranslational modification]
755732005288	intermolecular recognition site; other site
755732005289	dimerization interface [polypeptide binding]; other site
755732005290	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732005291	DNA binding site [nucleotide binding]
755732005292	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
755732005293	Glycoprotease family; Region: Peptidase_M22; pfam00814
755732005294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732005295	Major Facilitator Superfamily; Region: MFS_1; pfam07690
755732005296	putative substrate translocation pore; other site
755732005297	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
755732005298	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
755732005299	Chorismate mutase type II; Region: CM_2; smart00830
755732005300	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
755732005301	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
755732005302	hinge; other site
755732005303	active site
755732005304	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
755732005305	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
755732005306	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732005307	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
755732005308	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005309	binding surface
755732005310	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732005311	TPR motif; other site
755732005312	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732005313	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732005314	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732005315	adenylosuccinate lyase; Provisional; Region: PRK09285
755732005316	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
755732005317	tetramer interface [polypeptide binding]; other site
755732005318	active site
755732005319	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
755732005320	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
755732005321	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
755732005322	putative active site [active]
755732005323	catalytic triad [active]
755732005324	putative dimer interface [polypeptide binding]; other site
755732005325	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
755732005326	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
755732005327	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
755732005328	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
755732005329	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732005330	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732005331	DoxX-like family; Region: DoxX_2; pfam13564
755732005332	Predicted transcriptional regulators [Transcription]; Region: COG1733
755732005333	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
755732005334	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732005335	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732005336	ligand binding site [chemical binding]; other site
755732005337	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
755732005338	RNA/DNA hybrid binding site [nucleotide binding]; other site
755732005339	active site
755732005340	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005341	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
755732005342	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
755732005343	active site
755732005344	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
755732005345	GAF domain; Region: GAF; pfam01590
755732005346	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732005347	Histidine kinase; Region: HisKA_2; pfam07568
755732005348	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732005349	ATP binding site [chemical binding]; other site
755732005350	Mg2+ binding site [ion binding]; other site
755732005351	G-X-G motif; other site
755732005352	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732005353	Coenzyme A binding pocket [chemical binding]; other site
755732005354	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
755732005355	CoA-transferase family III; Region: CoA_transf_3; pfam02515
755732005356	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
755732005357	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
755732005358	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
755732005359	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
755732005360	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
755732005361	RNA binding site [nucleotide binding]; other site
755732005362	Protein of unknown function (DUF2459); Region: DUF2459; pfam09601
755732005363	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
755732005364	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
755732005365	active site
755732005366	HIGH motif; other site
755732005367	nucleotide binding site [chemical binding]; other site
755732005368	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
755732005369	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
755732005370	active site
755732005371	KMSKS motif; other site
755732005372	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
755732005373	tRNA binding surface [nucleotide binding]; other site
755732005374	anticodon binding site; other site
755732005375	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
755732005376	Transposase IS200 like; Region: Y1_Tnp; cl00848
755732005377	Two component regulator propeller; Region: Reg_prop; pfam07494
755732005378	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732005379	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732005380	DNA binding site [nucleotide binding]
755732005381	aspartate aminotransferase; Provisional; Region: PRK05764
755732005382	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
755732005383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732005384	homodimer interface [polypeptide binding]; other site
755732005385	catalytic residue [active]
755732005386	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
755732005387	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
755732005388	putative ribose interaction site [chemical binding]; other site
755732005389	putative ADP binding site [chemical binding]; other site
755732005390	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
755732005391	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732005392	S-adenosylmethionine binding site [chemical binding]; other site
755732005393	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732005394	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
755732005395	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
755732005396	TPR repeat; Region: TPR_11; pfam13414
755732005397	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005398	binding surface
755732005399	TPR motif; other site
755732005400	TPR repeat; Region: TPR_11; pfam13414
755732005401	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005402	binding surface
755732005403	TPR motif; other site
755732005404	TPR repeat; Region: TPR_11; pfam13414
755732005405	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005406	binding surface
755732005407	TPR motif; other site
755732005408	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732005409	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
755732005410	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
755732005411	Surface antigen; Region: Bac_surface_Ag; pfam01103
755732005412	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
755732005413	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
755732005414	active site
755732005415	intersubunit interface [polypeptide binding]; other site
755732005416	zinc binding site [ion binding]; other site
755732005417	Na+ binding site [ion binding]; other site
755732005418	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
755732005419	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
755732005420	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
755732005421	HutD; Region: HutD; cl01532
755732005422	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
755732005423	16S/18S rRNA binding site [nucleotide binding]; other site
755732005424	S13e-L30e interaction site [polypeptide binding]; other site
755732005425	25S rRNA binding site [nucleotide binding]; other site
755732005426	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
755732005427	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
755732005428	RNase E interface [polypeptide binding]; other site
755732005429	trimer interface [polypeptide binding]; other site
755732005430	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
755732005431	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
755732005432	RNase E interface [polypeptide binding]; other site
755732005433	trimer interface [polypeptide binding]; other site
755732005434	active site
755732005435	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
755732005436	RNA binding site [nucleotide binding]; other site
755732005437	domain interface; other site
755732005438	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
755732005439	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
755732005440	Transglycosylase; Region: Transgly; pfam00912
755732005441	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
755732005442	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
755732005443	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
755732005444	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
755732005445	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732005446	Histidine kinase; Region: His_kinase; pfam06580
755732005447	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732005448	Mg2+ binding site [ion binding]; other site
755732005449	G-X-G motif; other site
755732005450	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732005451	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732005452	active site
755732005453	phosphorylation site [posttranslational modification]
755732005454	intermolecular recognition site; other site
755732005455	dimerization interface [polypeptide binding]; other site
755732005456	LytTr DNA-binding domain; Region: LytTR; smart00850
755732005457	Protein of unknown function (DUF962); Region: DUF962; cl01879
755732005458	MG2 domain; Region: A2M_N; pfam01835
755732005459	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
755732005460	Alpha-2-macroglobulin family; Region: A2M; pfam00207
755732005461	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
755732005462	surface patch; other site
755732005463	thioester region; other site
755732005464	specificity defining residues; other site
755732005465	leukotriene A-4 hydrolase/aminopeptidase; Region: leuko_A4_hydro; TIGR02411
755732005466	Peptidase M1 family contains leukotriene A4 hydrolase; Region: M1_LTA4H; cd09599
755732005467	active site
755732005468	Zn binding site [ion binding]; other site
755732005469	Leukotriene A4 hydrolase, C-terminal; Region: Leuk-A4-hydro_C; pfam09127
755732005470	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
755732005471	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
755732005472	putative ATP binding site [chemical binding]; other site
755732005473	putative substrate interface [chemical binding]; other site
755732005474	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
755732005475	active site
755732005476	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732005477	putative substrate translocation pore; other site
755732005478	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732005479	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732005480	putative substrate translocation pore; other site
755732005481	POT family; Region: PTR2; cl17359
755732005482	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
755732005483	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
755732005484	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
755732005485	FMN binding site [chemical binding]; other site
755732005486	active site
755732005487	catalytic residues [active]
755732005488	substrate binding site [chemical binding]; other site
755732005489	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
755732005490	classical (c) SDRs; Region: SDR_c; cd05233
755732005491	NAD(P) binding site [chemical binding]; other site
755732005492	active site
755732005493	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
755732005494	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
755732005495	FAD binding pocket [chemical binding]; other site
755732005496	FAD binding motif [chemical binding]; other site
755732005497	phosphate binding motif [ion binding]; other site
755732005498	beta-alpha-beta structure motif; other site
755732005499	NAD(p) ribose binding residues [chemical binding]; other site
755732005500	NAD binding pocket [chemical binding]; other site
755732005501	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
755732005502	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
755732005503	catalytic loop [active]
755732005504	iron binding site [ion binding]; other site
755732005505	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
755732005506	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
755732005507	FAD binding pocket [chemical binding]; other site
755732005508	FAD binding motif [chemical binding]; other site
755732005509	phosphate binding motif [ion binding]; other site
755732005510	beta-alpha-beta structure motif; other site
755732005511	NAD(p) ribose binding residues [chemical binding]; other site
755732005512	NAD binding pocket [chemical binding]; other site
755732005513	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
755732005514	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
755732005515	catalytic loop [active]
755732005516	iron binding site [ion binding]; other site
755732005517	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
755732005518	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005519	TPR motif; other site
755732005520	binding surface
755732005521	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732005522	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732005523	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005524	binding surface
755732005525	TPR motif; other site
755732005526	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
755732005527	delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Region: D1pyr5carbox1; TIGR01236
755732005528	Glutamate binding site [chemical binding]; other site
755732005529	NAD binding site [chemical binding]; other site
755732005530	catalytic residues [active]
755732005531	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732005532	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732005533	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732005534	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
755732005535	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
755732005536	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
755732005537	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
755732005538	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
755732005539	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
755732005540	DNA polymerase III subunit beta; Validated; Region: PRK05643
755732005541	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
755732005542	putative DNA binding surface [nucleotide binding]; other site
755732005543	dimer interface [polypeptide binding]; other site
755732005544	beta-clamp/clamp loader binding surface; other site
755732005545	beta-clamp/translesion DNA polymerase binding surface; other site
755732005546	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
755732005547	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
755732005548	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
755732005549	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
755732005550	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; pfam01887
755732005551	PhoH-like protein; Region: PhoH; pfam02562
755732005552	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
755732005553	ATP binding site [chemical binding]; other site
755732005554	active site
755732005555	substrate binding site [chemical binding]; other site
755732005556	short chain dehydrogenase; Provisional; Region: PRK06181
755732005557	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732005558	NAD(P) binding site [chemical binding]; other site
755732005559	active site
755732005560	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732005561	Histidine kinase; Region: HisKA_2; pfam07568
755732005562	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732005563	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
755732005564	dimer interface [polypeptide binding]; other site
755732005565	active site
755732005566	Tellurite resistance protein TerB; Region: TerB; cl17311
755732005567	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732005568	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732005569	DinB superfamily; Region: DinB_2; pfam12867
755732005570	Bacterial SH3 domain; Region: SH3_4; pfam06347
755732005571	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
755732005572	NlpC/P60 family; Region: NLPC_P60; pfam00877
755732005573	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
755732005574	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
755732005575	dimer interface [polypeptide binding]; other site
755732005576	active site
755732005577	glycine-pyridoxal phosphate binding site [chemical binding]; other site
755732005578	folate binding site [chemical binding]; other site
755732005579	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
755732005580	Interdomain contacts; other site
755732005581	Cytokine receptor motif; other site
755732005582	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005583	Aspartyl/Asparaginyl beta-hydroxylase; Region: Asp_Arg_Hydrox; cl17820
755732005584	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
755732005585	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
755732005586	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
755732005587	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732005588	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_1; cd01832
755732005589	active site
755732005590	catalytic triad [active]
755732005591	oxyanion hole [active]
755732005592	fumarylacetoacetase; Region: PLN02856
755732005593	Domain of unknown function (DUF1969); Region: DUF1969; pfam09298
755732005594	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
755732005595	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
755732005596	HD domain; Region: HD_4; pfam13328
755732005597	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
755732005598	synthetase active site [active]
755732005599	NTP binding site [chemical binding]; other site
755732005600	metal binding site [ion binding]; metal-binding site
755732005601	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
755732005602	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
755732005603	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
755732005604	metal binding site 2 [ion binding]; metal-binding site
755732005605	putative DNA binding helix; other site
755732005606	metal binding site 1 [ion binding]; metal-binding site
755732005607	dimer interface [polypeptide binding]; other site
755732005608	structural Zn2+ binding site [ion binding]; other site
755732005609	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
755732005610	anti sigma factor interaction site; other site
755732005611	regulatory phosphorylation site [posttranslational modification]; other site
755732005612	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
755732005613	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
755732005614	GDP-binding site [chemical binding]; other site
755732005615	ACT binding site; other site
755732005616	IMP binding site; other site
755732005617	OstA-like protein; Region: OstA_2; pfam13100
755732005618	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
755732005619	OstA-like protein; Region: OstA; cl00844
755732005620	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
755732005621	Domain of unknown function DUF20; Region: UPF0118; pfam01594
755732005622	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
755732005623	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
755732005624	dimer interface [polypeptide binding]; other site
755732005625	active site
755732005626	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
755732005627	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
755732005628	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
755732005629	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
755732005630	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
755732005631	substrate binding site [chemical binding]; other site
755732005632	oxyanion hole (OAH) forming residues; other site
755732005633	trimer interface [polypeptide binding]; other site
755732005634	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
755732005635	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
755732005636	CoenzymeA binding site [chemical binding]; other site
755732005637	subunit interaction site [polypeptide binding]; other site
755732005638	PHB binding site; other site
755732005639	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
755732005640	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
755732005641	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732005642	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732005643	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732005644	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732005645	non-specific DNA binding site [nucleotide binding]; other site
755732005646	salt bridge; other site
755732005647	sequence-specific DNA binding site [nucleotide binding]; other site
755732005648	Fic family protein [Function unknown]; Region: COG3177
755732005649	Fic/DOC family; Region: Fic; pfam02661
755732005650	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
755732005651	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
755732005652	tetramer interface [polypeptide binding]; other site
755732005653	TPP-binding site [chemical binding]; other site
755732005654	heterodimer interface [polypeptide binding]; other site
755732005655	phosphorylation loop region [posttranslational modification]
755732005656	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
755732005657	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
755732005658	alpha subunit interface [polypeptide binding]; other site
755732005659	TPP binding site [chemical binding]; other site
755732005660	heterodimer interface [polypeptide binding]; other site
755732005661	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
755732005662	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
755732005663	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
755732005664	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
755732005665	trimer interface [polypeptide binding]; other site
755732005666	active site
755732005667	UDP-GlcNAc binding site [chemical binding]; other site
755732005668	lipid binding site [chemical binding]; lipid-binding site
755732005669	GAF domain; Region: GAF_3; pfam13492
755732005670	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
755732005671	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732005672	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
755732005673	active site
755732005674	FlgD Ig-like domain; Region: FlgD_ig; pfam13860
755732005675	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
755732005676	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
755732005677	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
755732005678	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
755732005679	dimer interface [polypeptide binding]; other site
755732005680	NADP binding site [chemical binding]; other site
755732005681	catalytic residues [active]
755732005682	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
755732005683	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
755732005684	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
755732005685	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
755732005686	substrate binding site [chemical binding]; other site
755732005687	oxyanion hole (OAH) forming residues; other site
755732005688	trimer interface [polypeptide binding]; other site
755732005689	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
755732005690	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
755732005691	active site
755732005692	DNA polymerase IV; Validated; Region: PRK02406
755732005693	DNA binding site [nucleotide binding]
755732005694	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732005695	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732005696	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732005697	DNA binding residues [nucleotide binding]
755732005698	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005699	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
755732005700	23S rRNA interface [nucleotide binding]; other site
755732005701	L3 interface [polypeptide binding]; other site
755732005702	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
755732005703	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
755732005704	rRNA interaction site [nucleotide binding]; other site
755732005705	S8 interaction site; other site
755732005706	putative laminin-1 binding site; other site
755732005707	elongation factor Ts; Provisional; Region: tsf; PRK09377
755732005708	UBA/TS-N domain; Region: UBA; pfam00627
755732005709	Elongation factor TS; Region: EF_TS; pfam00889
755732005710	Elongation factor TS; Region: EF_TS; pfam00889
755732005711	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
755732005712	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
755732005713	putative nucleotide binding site [chemical binding]; other site
755732005714	uridine monophosphate binding site [chemical binding]; other site
755732005715	homohexameric interface [polypeptide binding]; other site
755732005716	ribosome recycling factor; Reviewed; Region: frr; PRK00083
755732005717	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
755732005718	hinge region; other site
755732005719	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
755732005720	Family description; Region: UvrD_C_2; pfam13538
755732005721	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
755732005722	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
755732005723	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
755732005724	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732005725	Histidine kinase; Region: HisKA_2; pfam07568
755732005726	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732005727	ATP binding site [chemical binding]; other site
755732005728	Mg2+ binding site [ion binding]; other site
755732005729	G-X-G motif; other site
755732005730	WYL domain; Region: WYL; pfam13280
755732005731	enoyl-CoA hydratase; Provisional; Region: PRK08140
755732005732	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
755732005733	substrate binding site [chemical binding]; other site
755732005734	oxyanion hole (OAH) forming residues; other site
755732005735	trimer interface [polypeptide binding]; other site
755732005736	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
755732005737	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
755732005738	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
755732005739	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
755732005740	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
755732005741	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
755732005742	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005743	binding surface
755732005744	TPR motif; other site
755732005745	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732005746	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732005747	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732005748	DNA binding residues [nucleotide binding]
755732005749	6-phosphofructokinase; Provisional; Region: PRK03202
755732005750	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
755732005751	active site
755732005752	ADP/pyrophosphate binding site [chemical binding]; other site
755732005753	dimerization interface [polypeptide binding]; other site
755732005754	allosteric effector site; other site
755732005755	fructose-1,6-bisphosphate binding site; other site
755732005756	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
755732005757	active site
755732005758	multimer interface [polypeptide binding]; other site
755732005759	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
755732005760	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
755732005761	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
755732005762	FeoA domain; Region: FeoA; pfam04023
755732005763	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
755732005764	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
755732005765	intersubunit interface [polypeptide binding]; other site
755732005766	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
755732005767	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
755732005768	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
755732005769	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
755732005770	ABC-ATPase subunit  interface; other site
755732005771	dimer interface [polypeptide binding]; other site
755732005772	putative PBP binding regions; other site
755732005773	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
755732005774	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
755732005775	dimer interface [polypeptide binding]; other site
755732005776	putative PBP binding regions; other site
755732005777	ABC-ATPase subunit  interface; other site
755732005778	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
755732005779	putative active site [active]
755732005780	putative CoA binding site [chemical binding]; other site
755732005781	nudix motif; other site
755732005782	metal binding site [ion binding]; metal-binding site
755732005783	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
755732005784	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732005785	ATP binding site [chemical binding]; other site
755732005786	Mg2+ binding site [ion binding]; other site
755732005787	G-X-G motif; other site
755732005788	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
755732005789	anchoring element; other site
755732005790	dimer interface [polypeptide binding]; other site
755732005791	ATP binding site [chemical binding]; other site
755732005792	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
755732005793	active site
755732005794	putative metal-binding site [ion binding]; other site
755732005795	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
755732005796	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
755732005797	catalytic residues [active]
755732005798	dimer interface [polypeptide binding]; other site
755732005799	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732005800	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732005801	ligand binding site [chemical binding]; other site
755732005802	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005803	TPR motif; other site
755732005804	binding surface
755732005805	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
755732005806	catalytic center binding site [active]
755732005807	ATP binding site [chemical binding]; other site
755732005808	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
755732005809	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
755732005810	tandem repeat interface [polypeptide binding]; other site
755732005811	oligomer interface [polypeptide binding]; other site
755732005812	active site residues [active]
755732005813	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
755732005814	tandem repeat interface [polypeptide binding]; other site
755732005815	oligomer interface [polypeptide binding]; other site
755732005816	active site residues [active]
755732005817	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
755732005818	FAD binding domain; Region: FAD_binding_4; pfam01565
755732005819	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
755732005820	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
755732005821	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
755732005822	ATP binding site [chemical binding]; other site
755732005823	Mg++ binding site [ion binding]; other site
755732005824	motif III; other site
755732005825	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732005826	nucleotide binding region [chemical binding]; other site
755732005827	ATP-binding site [chemical binding]; other site
755732005828	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
755732005829	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
755732005830	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
755732005831	intersubunit interface [polypeptide binding]; other site
755732005832	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
755732005833	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
755732005834	ABC-ATPase subunit  interface; other site
755732005835	dimer interface [polypeptide binding]; other site
755732005836	putative PBP binding regions; other site
755732005837	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
755732005838	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
755732005839	Walker A/P-loop; other site
755732005840	ATP binding site [chemical binding]; other site
755732005841	Q-loop/lid; other site
755732005842	ABC transporter signature motif; other site
755732005843	Walker B; other site
755732005844	D-loop; other site
755732005845	H-loop/switch region; other site
755732005846	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
755732005847	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
755732005848	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732005849	Walker A motif; other site
755732005850	ATP binding site [chemical binding]; other site
755732005851	Walker B motif; other site
755732005852	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
755732005853	Methyltransferase domain; Region: Methyltransf_23; pfam13489
755732005854	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732005855	S-adenosylmethionine binding site [chemical binding]; other site
755732005856	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732005857	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732005858	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732005859	DNA binding residues [nucleotide binding]
755732005860	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732005861	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732005862	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
755732005863	dimer interface [polypeptide binding]; other site
755732005864	catalytic triad [active]
755732005865	peroxidatic and resolving cysteines [active]
755732005866	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: LpqC; COG3509
755732005867	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005868	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
755732005869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732005870	Major Facilitator Superfamily; Region: MFS_1; pfam07690
755732005871	putative substrate translocation pore; other site
755732005872	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732005873	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732005874	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
755732005875	MarR family; Region: MarR_2; pfam12802
755732005876	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
755732005877	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
755732005878	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
755732005879	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
755732005880	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005881	binding surface
755732005882	TPR motif; other site
755732005883	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732005884	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732005885	binding surface
755732005886	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732005887	TPR motif; other site
755732005888	TPR repeat; Region: TPR_11; pfam13414
755732005889	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732005890	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732005891	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732005892	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
755732005893	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
755732005894	GIY-YIG motif/motif A; other site
755732005895	putative active site [active]
755732005896	putative metal binding site [ion binding]; other site
755732005897	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
755732005898	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732005899	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
755732005900	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
755732005901	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
755732005902	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09560
755732005903	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
755732005904	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
755732005905	NAD(P) binding pocket [chemical binding]; other site
755732005906	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
755732005907	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
755732005908	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
755732005909	active site
755732005910	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
755732005911	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
755732005912	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732005913	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
755732005914	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
755732005915	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
755732005916	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
755732005917	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
755732005918	active site
755732005919	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
755732005920	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
755732005921	homotrimer interaction site [polypeptide binding]; other site
755732005922	zinc binding site [ion binding]; other site
755732005923	CDP-binding sites; other site
755732005924	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
755732005925	biotin synthase; Region: bioB; TIGR00433
755732005926	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732005927	FeS/SAM binding site; other site
755732005928	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
755732005929	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
755732005930	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
755732005931	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732005932	catalytic residue [active]
755732005933	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
755732005934	DNA-binding site [nucleotide binding]; DNA binding site
755732005935	RNA-binding motif; other site
755732005936	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
755732005937	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
755732005938	WHG domain; Region: WHG; pfam13305
755732005939	Outer membrane efflux protein; Region: OEP; pfam02321
755732005940	Outer membrane efflux protein; Region: OEP; pfam02321
755732005941	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732005942	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732005943	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732005944	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732005945	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005946	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
755732005947	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732005948	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
755732005949	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732005950	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732005951	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732005952	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
755732005953	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732005954	TPR motif; other site
755732005955	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732005956	binding surface
755732005957	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732005958	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732005959	dimer interface [polypeptide binding]; other site
755732005960	phosphorylation site [posttranslational modification]
755732005961	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732005962	ATP binding site [chemical binding]; other site
755732005963	Mg2+ binding site [ion binding]; other site
755732005964	G-X-G motif; other site
755732005965	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732005966	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732005967	active site
755732005968	phosphorylation site [posttranslational modification]
755732005969	intermolecular recognition site; other site
755732005970	dimerization interface [polypeptide binding]; other site
755732005971	LytTr DNA-binding domain; Region: LytTR; smart00850
755732005972	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
755732005973	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
755732005974	Tim44-like domain; Region: Tim44; cl09208
755732005975	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
755732005976	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
755732005977	dimerization interface [polypeptide binding]; other site
755732005978	ligand binding site [chemical binding]; other site
755732005979	NADP binding site [chemical binding]; other site
755732005980	catalytic site [active]
755732005981	Domain of unknown function (DUF4180); Region: DUF4180; pfam13788
755732005982	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
755732005983	putative active site [active]
755732005984	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
755732005985	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR1; cd08267
755732005986	putative NAD(P) binding site [chemical binding]; other site
755732005987	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
755732005988	Uncharacterized protein family (UPF0156); Region: RHH_2; pfam03693
755732005989	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
755732005990	putative catalytic site [active]
755732005991	putative metal binding site [ion binding]; other site
755732005992	putative phosphate binding site [ion binding]; other site
755732005993	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
755732005994	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732005995	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818
755732005996	putative hydrophobic ligand binding site [chemical binding]; other site
755732005997	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
755732005998	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
755732005999	Zn2+ binding site [ion binding]; other site
755732006000	Mg2+ binding site [ion binding]; other site
755732006001	Response regulator receiver domain; Region: Response_reg; pfam00072
755732006002	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006003	active site
755732006004	phosphorylation site [posttranslational modification]
755732006005	intermolecular recognition site; other site
755732006006	dimerization interface [polypeptide binding]; other site
755732006007	PglZ domain; Region: PglZ; pfam08665
755732006008	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
755732006009	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
755732006010	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
755732006011	hexamer interface [polypeptide binding]; other site
755732006012	ligand binding site [chemical binding]; other site
755732006013	putative active site [active]
755732006014	NAD(P) binding site [chemical binding]; other site
755732006015	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732006016	Histidine kinase; Region: HisKA_2; pfam07568
755732006017	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732006018	Mg2+ binding site [ion binding]; other site
755732006019	G-X-G motif; other site
755732006020	AAA domain; Region: AAA_11; pfam13086
755732006021	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732006022	ATP binding site [chemical binding]; other site
755732006023	AAA domain; Region: AAA_30; pfam13604
755732006024	AAA domain; Region: AAA_12; pfam13087
755732006025	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
755732006026	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
755732006027	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
755732006028	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732006029	Walker A/P-loop; other site
755732006030	ATP binding site [chemical binding]; other site
755732006031	Q-loop/lid; other site
755732006032	ABC transporter signature motif; other site
755732006033	Walker B; other site
755732006034	D-loop; other site
755732006035	H-loop/switch region; other site
755732006036	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732006037	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732006038	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732006039	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
755732006040	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732006041	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cd10981
755732006042	Zn binding site [ion binding]; other site
755732006043	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; pfam04029
755732006044	Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Region: COG2045
755732006045	integral membrane protein; Region: integ_memb_HG; TIGR03954
755732006046	excinuclease ABC subunit B; Provisional; Region: PRK05298
755732006047	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732006048	ATP binding site [chemical binding]; other site
755732006049	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732006050	nucleotide binding region [chemical binding]; other site
755732006051	ATP-binding site [chemical binding]; other site
755732006052	Ultra-violet resistance protein B; Region: UvrB; pfam12344
755732006053	UvrB/uvrC motif; Region: UVR; pfam02151
755732006054	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
755732006055	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732006056	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732006057	Mg-chelatase subunit ChlI [Coenzyme metabolism]; Region: ChlI; COG1239
755732006058	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
755732006059	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
755732006060	metal ion-dependent adhesion site (MIDAS); other site
755732006061	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732006062	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
755732006063	active site
755732006064	hypothetical protein; Provisional; Region: PRK02268
755732006065	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
755732006066	MarR family; Region: MarR; pfam01047
755732006067	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732006068	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006069	active site
755732006070	phosphorylation site [posttranslational modification]
755732006071	intermolecular recognition site; other site
755732006072	dimerization interface [polypeptide binding]; other site
755732006073	LytTr DNA-binding domain; Region: LytTR; smart00850
755732006074	Histidine kinase; Region: His_kinase; pfam06580
755732006075	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732006076	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732006077	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
755732006078	FG-GAP repeat; Region: FG-GAP_2; pfam14312
755732006079	FG-GAP repeat; Region: FG-GAP_2; pfam14312
755732006080	FG-GAP repeat; Region: FG-GAP_2; pfam14312
755732006081	FG-GAP repeat; Region: FG-GAP_2; pfam14312
755732006082	FG-GAP repeat; Region: FG-GAP_2; pfam14312
755732006083	FG-GAP repeat; Region: FG-GAP_2; pfam14312
755732006084	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006085	AAA domain; Region: AAA_28; pfam13521
755732006086	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
755732006087	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
755732006088	WXG100 protein secretion system (Wss), protein EssA; Region: EssA; cl11266
755732006089	A bacterial subgroup of the C-type lectin-like (CTLD) domain; a subgroup of bacterial protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins; Region: CLECT_VCBS; cd03603
755732006090	ligand binding surface [chemical binding]; other site
755732006091	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006092	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
755732006093	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732006094	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006095	probable DNA metabolism protein; Region: SAM_7_link_chp; TIGR03915
755732006096	putative DNA modification/repair radical SAM protein; Region: rSAM_link_UDG; TIGR03916
755732006097	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732006098	FeS/SAM binding site; other site
755732006099	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732006100	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732006101	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
755732006102	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732006103	Protein of unknown function (DUF692); Region: DUF692; cl01263
755732006104	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
755732006105	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
755732006106	four helix bundle protein; Region: TIGR02436
755732006107	Uncharacterized protein conserved in bacteria (DUF2186); Region: DUF2186; pfam09952
755732006108	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
755732006109	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
755732006110	exodeoxyribonuclease X; Provisional; Region: PRK07983
755732006111	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
755732006112	active site
755732006113	catalytic site [active]
755732006114	substrate binding site [chemical binding]; other site
755732006115	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006116	TPR motif; other site
755732006117	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006118	binding surface
755732006119	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732006120	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732006121	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732006122	ligand binding site [chemical binding]; other site
755732006123	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
755732006124	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
755732006125	E3 interaction surface; other site
755732006126	lipoyl attachment site [posttranslational modification]; other site
755732006127	e3 binding domain; Region: E3_binding; pfam02817
755732006128	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
755732006129	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
755732006130	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
755732006131	Probable Catalytic site; other site
755732006132	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
755732006133	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
755732006134	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
755732006135	homotrimer interaction site [polypeptide binding]; other site
755732006136	putative active site [active]
755732006137	Glutamine amidotransferase class-I; Region: GATase; pfam00117
755732006138	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
755732006139	glutamine binding [chemical binding]; other site
755732006140	catalytic triad [active]
755732006141	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
755732006142	AAA domain; Region: AAA_33; pfam13671
755732006143	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
755732006144	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
755732006145	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
755732006146	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
755732006147	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
755732006148	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732006149	Walker A motif; other site
755732006150	ATP binding site [chemical binding]; other site
755732006151	Walker B motif; other site
755732006152	arginine finger; other site
755732006153	Peptidase family M41; Region: Peptidase_M41; pfam01434
755732006154	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
755732006155	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
755732006156	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
755732006157	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732006158	active site
755732006159	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
755732006160	active site
755732006161	Ap6A binding site [chemical binding]; other site
755732006162	nudix motif; other site
755732006163	metal binding site [ion binding]; metal-binding site
755732006164	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
755732006165	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
755732006166	active site
755732006167	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
755732006168	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
755732006169	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732006170	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732006171	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732006172	hypothetical protein; Provisional; Region: PRK09256
755732006173	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732006174	dimerization interface [polypeptide binding]; other site
755732006175	putative DNA binding site [nucleotide binding]; other site
755732006176	putative Zn2+ binding site [ion binding]; other site
755732006177	Peptidase family M48; Region: Peptidase_M48; cl12018
755732006178	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
755732006179	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732006180	dimerization interface [polypeptide binding]; other site
755732006181	putative DNA binding site [nucleotide binding]; other site
755732006182	putative Zn2+ binding site [ion binding]; other site
755732006183	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
755732006184	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
755732006185	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732006186	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006187	TPR motif; other site
755732006188	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006189	binding surface
755732006190	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006191	binding surface
755732006192	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006193	TPR motif; other site
755732006194	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006195	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006196	binding surface
755732006197	TPR motif; other site
755732006198	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006199	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732006200	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
755732006201	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
755732006202	Transposase; Region: DDE_Tnp_ISL3; pfam01610
755732006203	Response regulator receiver domain; Region: Response_reg; pfam00072
755732006204	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006205	active site
755732006206	phosphorylation site [posttranslational modification]
755732006207	intermolecular recognition site; other site
755732006208	dimerization interface [polypeptide binding]; other site
755732006209	LytTr DNA-binding domain; Region: LytTR; cl04498
755732006210	Histidine kinase; Region: His_kinase; pfam06580
755732006211	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
755732006212	B12 binding site [chemical binding]; other site
755732006213	cobalt ligand [ion binding]; other site
755732006214	Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism]; Region: ArgK; COG1703
755732006215	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
755732006216	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, unknown subfamily 1; composed of uncharacterized bacterial proteins containing a C-terminal MCM domain. MCM catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. The...; Region: MM_CoA_mutase_1; cd03678
755732006217	putative active site [active]
755732006218	putative substrate binding site [chemical binding]; other site
755732006219	putative coenzyme B12 binding site [chemical binding]; other site
755732006220	chromosomal replication initiation protein; Provisional; Region: dnaA; PRK14088
755732006221	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
755732006222	heterodimerization interface [polypeptide binding]; other site
755732006223	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732006224	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006225	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
755732006226	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
755732006227	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
755732006228	competence damage-inducible protein A; Provisional; Region: PRK00549
755732006229	putative MPT binding site; other site
755732006230	Competence-damaged protein; Region: CinA; pfam02464
755732006231	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
755732006232	ribosomal protein L33; Region: rpl33; CHL00104
755732006233	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
755732006234	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
755732006235	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
755732006236	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
755732006237	P loop; other site
755732006238	GTP binding site [chemical binding]; other site
755732006239	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
755732006240	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732006241	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732006242	DNA binding residues [nucleotide binding]
755732006243	Bacterial proteins similar to Porphyromonas gingivalis HmuY and the C-terminal domain of PARMER_03218; Region: HmuY_like; cl12009
755732006244	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006245	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
755732006246	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
755732006247	intersubunit interface [polypeptide binding]; other site
755732006248	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
755732006249	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
755732006250	ABC-ATPase subunit  interface; other site
755732006251	dimer interface [polypeptide binding]; other site
755732006252	putative PBP binding regions; other site
755732006253	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
755732006254	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
755732006255	Walker A/P-loop; other site
755732006256	ATP binding site [chemical binding]; other site
755732006257	Q-loop/lid; other site
755732006258	ABC transporter signature motif; other site
755732006259	Walker B; other site
755732006260	D-loop; other site
755732006261	H-loop/switch region; other site
755732006262	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
755732006263	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
755732006264	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
755732006265	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732006266	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
755732006267	Bacterial proteins similar to Porphyromonas gingivalis HmuY and the C-terminal domain of PARMER_03218; Region: HmuY_like; cl12009
755732006268	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
755732006269	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
755732006270	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
755732006271	dimer interface [polypeptide binding]; other site
755732006272	motif 1; other site
755732006273	active site
755732006274	motif 2; other site
755732006275	motif 3; other site
755732006276	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
755732006277	anticodon binding site; other site
755732006278	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
755732006279	active sites [active]
755732006280	tetramer interface [polypeptide binding]; other site
755732006281	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006282	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006283	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006284	binding surface
755732006285	TPR motif; other site
755732006286	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006287	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006288	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006289	binding surface
755732006290	TPR motif; other site
755732006291	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006292	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732006293	Histidine kinase; Region: HisKA_3; pfam07730
755732006294	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732006295	ATP binding site [chemical binding]; other site
755732006296	Mg2+ binding site [ion binding]; other site
755732006297	G-X-G motif; other site
755732006298	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732006299	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006300	active site
755732006301	phosphorylation site [posttranslational modification]
755732006302	intermolecular recognition site; other site
755732006303	dimerization interface [polypeptide binding]; other site
755732006304	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732006305	dimerization interface [polypeptide binding]; other site
755732006306	DNA binding residues [nucleotide binding]
755732006307	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006308	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
755732006309	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732006310	Walker A/P-loop; other site
755732006311	ATP binding site [chemical binding]; other site
755732006312	Q-loop/lid; other site
755732006313	ABC transporter signature motif; other site
755732006314	Walker B; other site
755732006315	D-loop; other site
755732006316	H-loop/switch region; other site
755732006317	ABC transporter; Region: ABC_tran_2; pfam12848
755732006318	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732006319	putative DNA binding site [nucleotide binding]; other site
755732006320	putative Zn2+ binding site [ion binding]; other site
755732006321	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
755732006322	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
755732006323	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
755732006324	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
755732006325	active site
755732006326	nucleophile elbow; other site
755732006327	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
755732006328	Surface antigen; Region: Bac_surface_Ag; pfam01103
755732006329	heat shock protein 90; Provisional; Region: PRK05218
755732006330	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732006331	ATP binding site [chemical binding]; other site
755732006332	Mg2+ binding site [ion binding]; other site
755732006333	G-X-G motif; other site
755732006334	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
755732006335	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
755732006336	putative metal binding site [ion binding]; other site
755732006337	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732006338	HSP70 interaction site [polypeptide binding]; other site
755732006339	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732006340	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
755732006341	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732006342	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
755732006343	putative SAM binding site [chemical binding]; other site
755732006344	homodimer interface [polypeptide binding]; other site
755732006345	Low molecular weight phosphatase family; Region: LMWPc; cd00115
755732006346	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
755732006347	active site
755732006348	RNA polymerase sigma factor, cyanobacterial RpoD-like family; Region: Sig70-cyanoRpoD; TIGR02997
755732006349	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
755732006350	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732006351	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
755732006352	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732006353	DNA binding residues [nucleotide binding]
755732006354	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
755732006355	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732006356	ATP binding site [chemical binding]; other site
755732006357	putative Mg++ binding site [ion binding]; other site
755732006358	helicase superfamily c-terminal domain; Region: HELICc; smart00490
755732006359	ATP-binding site [chemical binding]; other site
755732006360	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
755732006361	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732006362	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
755732006363	active site
755732006364	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732006365	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
755732006366	active site
755732006367	hypothetical protein; Provisional; Region: PRK10279
755732006368	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
755732006369	nucleophile elbow; other site
755732006370	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
755732006371	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
755732006372	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
755732006373	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006374	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006375	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
755732006376	dimer interface [polypeptide binding]; other site
755732006377	Citrate synthase; Region: Citrate_synt; pfam00285
755732006378	active site
755732006379	citrylCoA binding site [chemical binding]; other site
755732006380	NADH binding [chemical binding]; other site
755732006381	cationic pore residues; other site
755732006382	oxalacetate/citrate binding site [chemical binding]; other site
755732006383	coenzyme A binding site [chemical binding]; other site
755732006384	catalytic triad [active]
755732006385	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
755732006386	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
755732006387	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732006388	Lamin Tail Domain; Region: LTD; pfam00932
755732006389	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006390	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732006391	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732006392	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
755732006393	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732006394	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
755732006395	generic binding surface II; other site
755732006396	generic binding surface I; other site
755732006397	Endonuclease I; Region: Endonuclease_1; cl01003
755732006398	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006399	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
755732006400	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
755732006401	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
755732006402	active site
755732006403	metal binding site [ion binding]; metal-binding site
755732006404	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732006405	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
755732006406	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006407	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
755732006408	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
755732006409	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
755732006410	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
755732006411	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
755732006412	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
755732006413	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
755732006414	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
755732006415	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732006416	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
755732006417	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
755732006418	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
755732006419	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
755732006420	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
755732006421	homodimer interface [polypeptide binding]; other site
755732006422	metal binding site [ion binding]; metal-binding site
755732006423	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
755732006424	homodimer interface [polypeptide binding]; other site
755732006425	active site
755732006426	putative chemical substrate binding site [chemical binding]; other site
755732006427	metal binding site [ion binding]; metal-binding site
755732006428	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
755732006429	Family description; Region: ACT_7; pfam13840
755732006430	cytidylate kinase; Provisional; Region: cmk; PRK00023
755732006431	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
755732006432	CMP-binding site; other site
755732006433	The sites determining sugar specificity; other site
755732006434	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732006435	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
755732006436	active site
755732006437	metal binding site [ion binding]; metal-binding site
755732006438	homotetramer interface [polypeptide binding]; other site
755732006439	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
755732006440	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
755732006441	tetramer interface [polypeptide binding]; other site
755732006442	TPP-binding site [chemical binding]; other site
755732006443	heterodimer interface [polypeptide binding]; other site
755732006444	phosphorylation loop region [posttranslational modification]
755732006445	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
755732006446	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
755732006447	E3 interaction surface; other site
755732006448	lipoyl attachment site [posttranslational modification]; other site
755732006449	e3 binding domain; Region: E3_binding; pfam02817
755732006450	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
755732006451	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
755732006452	DNA-binding site [nucleotide binding]; DNA binding site
755732006453	RNA-binding motif; other site
755732006454	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
755732006455	Leucine rich repeat; Region: LRR_8; pfam13855
755732006456	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
755732006457	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
755732006458	putative trimer interface [polypeptide binding]; other site
755732006459	putative CoA binding site [chemical binding]; other site
755732006460	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
755732006461	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
755732006462	Catalytic domain of Protein Kinases; Region: PKc; cd00180
755732006463	active site
755732006464	ATP binding site [chemical binding]; other site
755732006465	substrate binding site [chemical binding]; other site
755732006466	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
755732006467	activation loop (A-loop); other site
755732006468	activation loop (A-loop); other site
755732006469	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732006470	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
755732006471	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732006472	Vitamin K-dependent gamma-carboxylase; Region: VKG_Carbox; cl02773
755732006473	Imelysin; Region: Peptidase_M75; pfam09375
755732006474	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
755732006475	Domain of unknown function (DUF1987); Region: DUF1987; pfam09345
755732006476	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
755732006477	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
755732006478	active site
755732006479	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
755732006480	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
755732006481	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006482	Predicted membrane protein (DUF2157); Region: DUF2157; cl10480
755732006483	GDYXXLXY protein; Region: GDYXXLXY; pfam14345
755732006484	Transposase IS200 like; Region: Y1_Tnp; pfam01797
755732006485	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
755732006486	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
755732006487	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
755732006488	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732006489	non-specific DNA binding site [nucleotide binding]; other site
755732006490	salt bridge; other site
755732006491	sequence-specific DNA binding site [nucleotide binding]; other site
755732006492	Domain of unknown function (DUF955); Region: DUF955; cl01076
755732006493	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
755732006494	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
755732006495	Walker A motif; other site
755732006496	ATP binding site [chemical binding]; other site
755732006497	GTPase subunit of restriction endonuclease [Defense mechanisms]; Region: McrB; COG1401
755732006498	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
755732006499	WYL domain; Region: WYL; cl14852
755732006500	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
755732006501	putative active site [active]
755732006502	putative NTP binding site [chemical binding]; other site
755732006503	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
755732006504	putative nucleic acid binding site [nucleotide binding]; other site
755732006505	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
755732006506	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
755732006507	HsdM N-terminal domain; Region: HsdM_N; pfam12161
755732006508	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
755732006509	Methyltransferase domain; Region: Methyltransf_26; pfam13659
755732006510	Uncharacterized conserved protein [Function unknown]; Region: COG1432
755732006511	Uncharacterized subfamily of N-terminal LabA-like domains; Region: LabA_like_N_1; cd11297
755732006512	putative metal binding site [ion binding]; other site
755732006513	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
755732006514	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006515	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
755732006516	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
755732006517	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
755732006518	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
755732006519	thiS-thiF/thiG interaction site; other site
755732006520	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
755732006521	ThiC-associated domain; Region: ThiC-associated; pfam13667
755732006522	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
755732006523	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
755732006524	thiamine phosphate binding site [chemical binding]; other site
755732006525	active site
755732006526	pyrophosphate binding site [ion binding]; other site
755732006527	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
755732006528	dimer interface [polypeptide binding]; other site
755732006529	substrate binding site [chemical binding]; other site
755732006530	ATP binding site [chemical binding]; other site
755732006531	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
755732006532	active site
755732006533	thiamine phosphate binding site [chemical binding]; other site
755732006534	pyrophosphate binding site [ion binding]; other site
755732006535	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
755732006536	ThiS interaction site; other site
755732006537	putative active site [active]
755732006538	tetramer interface [polypeptide binding]; other site
755732006539	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
755732006540	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732006541	FeS/SAM binding site; other site
755732006542	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
755732006543	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
755732006544	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
755732006545	ATP binding site [chemical binding]; other site
755732006546	substrate interface [chemical binding]; other site
755732006547	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
755732006548	putative active site [active]
755732006549	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
755732006550	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
755732006551	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
755732006552	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732006553	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732006554	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732006555	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732006556	DNA binding residues [nucleotide binding]
755732006557	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
755732006558	tryptophan tryptophylquinone biosynthesis enzyme MauG; Region: TTQ_mauG; TIGR03791
755732006559	YHYH protein; Region: YHYH; pfam14240
755732006560	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006561	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
755732006562	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
755732006563	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
755732006564	Walker A/P-loop; other site
755732006565	ATP binding site [chemical binding]; other site
755732006566	Q-loop/lid; other site
755732006567	ABC transporter signature motif; other site
755732006568	Walker B; other site
755732006569	D-loop; other site
755732006570	H-loop/switch region; other site
755732006571	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
755732006572	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006573	TPR repeat; Region: TPR_11; pfam13414
755732006574	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006575	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006576	binding surface
755732006577	TPR motif; other site
755732006578	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006579	binding surface
755732006580	TPR motif; other site
755732006581	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006582	Histidine kinase; Region: HisKA_3; pfam07730
755732006583	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732006584	ATP binding site [chemical binding]; other site
755732006585	Mg2+ binding site [ion binding]; other site
755732006586	G-X-G motif; other site
755732006587	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732006588	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006589	active site
755732006590	phosphorylation site [posttranslational modification]
755732006591	intermolecular recognition site; other site
755732006592	dimerization interface [polypeptide binding]; other site
755732006593	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732006594	DNA binding residues [nucleotide binding]
755732006595	dimerization interface [polypeptide binding]; other site
755732006596	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006597	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732006598	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732006599	ligand binding site [chemical binding]; other site
755732006600	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
755732006601	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
755732006602	tetramer interface [polypeptide binding]; other site
755732006603	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732006604	catalytic residue [active]
755732006605	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732006606	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
755732006607	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
755732006608	putative active site [active]
755732006609	putative metal binding residues [ion binding]; other site
755732006610	signature motif; other site
755732006611	putative dimer interface [polypeptide binding]; other site
755732006612	putative phosphate binding site [ion binding]; other site
755732006613	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u8; cd10932
755732006614	NodB motif; other site
755732006615	putative active site [active]
755732006616	putative catalytic site [active]
755732006617	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
755732006618	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
755732006619	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732006620	NAD(P) binding site [chemical binding]; other site
755732006621	active site
755732006622	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
755732006623	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
755732006624	NAD(P) binding site [chemical binding]; other site
755732006625	homodimer interface [polypeptide binding]; other site
755732006626	substrate binding site [chemical binding]; other site
755732006627	active site
755732006628	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
755732006629	active site
755732006630	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732006631	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
755732006632	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
755732006633	putative active site [active]
755732006634	putative metal binding site [ion binding]; other site
755732006635	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732006636	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732006637	catalytic residues [active]
755732006638	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
755732006639	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732006640	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732006641	catalytic residues [active]
755732006642	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
755732006643	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
755732006644	GatB domain; Region: GatB_Yqey; smart00845
755732006645	purine nucleoside phosphorylase; Provisional; Region: PRK08202
755732006646	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
755732006647	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
755732006648	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
755732006649	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
755732006650	active site
755732006651	Uncharacterized conserved protein [Function unknown]; Region: COG0327
755732006652	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
755732006653	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
755732006654	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
755732006655	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
755732006656	Putative zinc ribbon domain; Region: DUF164; pfam02591
755732006657	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
755732006658	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
755732006659	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
755732006660	catalytic residues [active]
755732006661	dimer interface [polypeptide binding]; other site
755732006662	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
755732006663	Predicted flavoprotein [General function prediction only]; Region: COG0431
755732006664	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
755732006665	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006666	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732006667	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732006668	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732006669	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732006670	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732006671	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732006672	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732006673	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006674	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
755732006675	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
755732006676	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732006677	catalytic residue [active]
755732006678	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
755732006679	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
755732006680	metal ion-dependent adhesion site (MIDAS); other site
755732006681	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006682	active site residue [active]
755732006683	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732006684	catalytic residues [active]
755732006685	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006686	active site residue [active]
755732006687	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006688	active site residue [active]
755732006689	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
755732006690	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006691	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
755732006692	active site residue [active]
755732006693	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
755732006694	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732006695	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732006696	ligand binding site [chemical binding]; other site
755732006697	flexible hinge region; other site
755732006698	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
755732006699	putative switch regulator; other site
755732006700	non-specific DNA interactions [nucleotide binding]; other site
755732006701	DNA binding site [nucleotide binding]
755732006702	sequence specific DNA binding site [nucleotide binding]; other site
755732006703	putative cAMP binding site [chemical binding]; other site
755732006704	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; cl01408
755732006705	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
755732006706	putative hydrophobic ligand binding site [chemical binding]; other site
755732006707	recombination protein F; Reviewed; Region: recF; PRK00064
755732006708	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732006709	Walker A/P-loop; other site
755732006710	ATP binding site [chemical binding]; other site
755732006711	Q-loop/lid; other site
755732006712	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732006713	ABC transporter signature motif; other site
755732006714	Walker B; other site
755732006715	D-loop; other site
755732006716	H-loop/switch region; other site
755732006717	Protein of unknown function (DUF721); Region: DUF721; pfam05258
755732006718	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
755732006719	active site
755732006720	oligomerization interface [polypeptide binding]; other site
755732006721	metal binding site [ion binding]; metal-binding site
755732006722	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
755732006723	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
755732006724	active site
755732006725	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006726	binding surface
755732006727	TPR motif; other site
755732006728	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006729	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006730	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732006731	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732006732	binding surface
755732006733	TPR motif; other site
755732006734	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732006735	Histidine kinase; Region: HisKA_3; pfam07730
755732006736	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732006737	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006738	active site
755732006739	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732006740	phosphorylation site [posttranslational modification]
755732006741	intermolecular recognition site; other site
755732006742	dimerization interface [polypeptide binding]; other site
755732006743	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732006744	DNA binding residues [nucleotide binding]
755732006745	dimerization interface [polypeptide binding]; other site
755732006746	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732006747	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732006748	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732006749	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732006750	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732006751	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732006752	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732006753	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732006754	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732006755	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732006756	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732006757	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006758	Peptidase family M48; Region: Peptidase_M48; cl12018
755732006759	amino acid transporter; Region: 2A0306; TIGR00909
755732006760	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
755732006761	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
755732006762	translocation protein TolB; Provisional; Region: tolB; PRK05137
755732006763	signal recognition particle protein; Provisional; Region: PRK10867
755732006764	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
755732006765	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
755732006766	P loop; other site
755732006767	GTP binding site [chemical binding]; other site
755732006768	Signal peptide binding domain; Region: SRP_SPB; pfam02978
755732006769	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006770	active site residue [active]
755732006771	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732006772	catalytic residues [active]
755732006773	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732006774	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
755732006775	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006776	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006777	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006778	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006779	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006780	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732006781	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732006782	Calx-beta domain; Region: Calx-beta; cl02522
755732006783	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006784	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006785	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732006786	Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Region: PKD; smart00089
755732006787	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732006788	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732006789	DinB family; Region: DinB; cl17821
755732006790	Predicted transcriptional regulator [Transcription]; Region: COG2378
755732006791	HTH domain; Region: HTH_11; pfam08279
755732006792	WYL domain; Region: WYL; pfam13280
755732006793	FAD binding domain; Region: FAD_binding_4; pfam01565
755732006794	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
755732006795	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
755732006796	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
755732006797	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
755732006798	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732006799	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
755732006800	active site
755732006801	metal binding site [ion binding]; metal-binding site
755732006802	TPR repeat; Region: TPR_11; pfam13414
755732006803	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006804	TPR motif; other site
755732006805	binding surface
755732006806	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732006807	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732006808	ligand binding site [chemical binding]; other site
755732006809	TPR repeat; Region: TPR_11; pfam13414
755732006810	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006811	binding surface
755732006812	TPR motif; other site
755732006813	TPR repeat; Region: TPR_11; pfam13414
755732006814	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006815	binding surface
755732006816	TPR motif; other site
755732006817	TPR repeat; Region: TPR_11; pfam13414
755732006818	TPR repeat; Region: TPR_11; pfam13414
755732006819	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006820	binding surface
755732006821	TPR motif; other site
755732006822	TPR repeat; Region: TPR_11; pfam13414
755732006823	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732006824	binding surface
755732006825	TPR motif; other site
755732006826	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
755732006827	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
755732006828	dimer interface [polypeptide binding]; other site
755732006829	active site
755732006830	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006831	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
755732006832	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
755732006833	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732006834	active site
755732006835	motif I; other site
755732006836	motif II; other site
755732006837	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
755732006838	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
755732006839	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
755732006840	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
755732006841	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732006842	nucleotide binding region [chemical binding]; other site
755732006843	ATP-binding site [chemical binding]; other site
755732006844	SEC-C motif; Region: SEC-C; pfam02810
755732006845	GMP synthase; Reviewed; Region: guaA; PRK00074
755732006846	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
755732006847	AMP/PPi binding site [chemical binding]; other site
755732006848	candidate oxyanion hole; other site
755732006849	catalytic triad [active]
755732006850	potential glutamine specificity residues [chemical binding]; other site
755732006851	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
755732006852	ATP Binding subdomain [chemical binding]; other site
755732006853	Ligand Binding sites [chemical binding]; other site
755732006854	Dimerization subdomain; other site
755732006855	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732006856	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
755732006857	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732006858	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
755732006859	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
755732006860	ligand binding site [chemical binding]; other site
755732006861	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
755732006862	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
755732006863	proline dehydrogenase; Region: PLN02681
755732006864	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
755732006865	active site
755732006866	dimer interface [polypeptide binding]; other site
755732006867	metal binding site [ion binding]; metal-binding site
755732006868	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
755732006869	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
755732006870	DNA binding residues [nucleotide binding]
755732006871	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
755732006872	NlpC/P60 family; Region: NLPC_P60; pfam00877
755732006873	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
755732006874	Major Facilitator Superfamily; Region: MFS_1; pfam07690
755732006875	putative substrate translocation pore; other site
755732006876	methionine sulfoxide reductase A; Provisional; Region: PRK14054
755732006877	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
755732006878	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
755732006879	Leucine rich repeat; Region: LRR_8; pfam13855
755732006880	Substrate binding site [chemical binding]; other site
755732006881	Leucine rich repeat; Region: LRR_8; pfam13855
755732006882	CAAX protease self-immunity; Region: Abi; pfam02517
755732006883	Cupin superfamily (DUF985); Region: Cupin_5; pfam06172
755732006884	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
755732006885	putative FMN binding site [chemical binding]; other site
755732006886	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732006887	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732006888	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
755732006889	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
755732006890	active site
755732006891	(T/H)XGH motif; other site
755732006892	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
755732006893	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732006894	S-adenosylmethionine binding site [chemical binding]; other site
755732006895	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
755732006896	AAA domain; Region: AAA_30; pfam13604
755732006897	Family description; Region: UvrD_C_2; pfam13538
755732006898	Family description; Region: VCBS; pfam13517
755732006899	Family description; Region: VCBS; pfam13517
755732006900	Family description; Region: VCBS; pfam13517
755732006901	Family description; Region: VCBS; pfam13517
755732006902	Family description; Region: VCBS; pfam13517
755732006903	Family description; Region: VCBS; pfam13517
755732006904	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732006905	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
755732006906	Response regulator receiver domain; Region: Response_reg; pfam00072
755732006907	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732006908	active site
755732006909	phosphorylation site [posttranslational modification]
755732006910	intermolecular recognition site; other site
755732006911	dimerization interface [polypeptide binding]; other site
755732006912	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
755732006913	Int/Topo IB signature motif; other site
755732006914	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732006915	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732006916	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
755732006917	Walker A/P-loop; other site
755732006918	ATP binding site [chemical binding]; other site
755732006919	Uncharacterized protein conserved in bacteria (DUF2186); Region: DUF2186; pfam09952
755732006920	Predicted nucleotidyltransferase [General function prediction    only]; Region: COG4849
755732006921	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
755732006922	Methyltransferase domain; Region: Methyltransf_26; pfam13659
755732006923	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
755732006924	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
755732006925	Nuclease-related domain; Region: NERD; pfam08378
755732006926	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
755732006927	Catalytic domain of Protein Kinases; Region: PKc; cd00180
755732006928	active site
755732006929	ATP binding site [chemical binding]; other site
755732006930	substrate binding site [chemical binding]; other site
755732006931	activation loop (A-loop); other site
755732006932	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
755732006933	Catalytic domain of Protein Kinases; Region: PKc; cd00180
755732006934	active site
755732006935	ATP binding site [chemical binding]; other site
755732006936	substrate binding site [chemical binding]; other site
755732006937	activation loop (A-loop); other site
755732006938	Zonular occludens toxin (Zot); Region: Zot; cl17485
755732006939	AAA-like domain; Region: AAA_10; pfam12846
755732006940	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
755732006941	active site
755732006942	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
755732006943	Int/Topo IB signature motif; other site
755732006944	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
755732006945	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732006946	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cl02712
755732006947	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
755732006948	RNA helicase; Region: RNA_helicase; pfam00910
755732006949	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732006950	non-specific DNA binding site [nucleotide binding]; other site
755732006951	salt bridge; other site
755732006952	sequence-specific DNA binding site [nucleotide binding]; other site
755732006953	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
755732006954	HsdM N-terminal domain; Region: HsdM_N; pfam12161
755732006955	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732006956	S-adenosylmethionine binding site [chemical binding]; other site
755732006957	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
755732006958	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
755732006959	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
755732006960	AAA domain; Region: AAA_13; pfam13166
755732006961	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
755732006962	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
755732006963	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732006964	ATP binding site [chemical binding]; other site
755732006965	putative Mg++ binding site [ion binding]; other site
755732006966	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
755732006967	Domain of unknown function (DUF955); Region: DUF955; pfam06114
755732006968	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732006969	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732006970	non-specific DNA binding site [nucleotide binding]; other site
755732006971	salt bridge; other site
755732006972	sequence-specific DNA binding site [nucleotide binding]; other site
755732006973	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
755732006974	metal binding triad [ion binding]; metal-binding site
755732006975	SEC-C motif; Region: SEC-C; pfam02810
755732006976	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
755732006977	Int/Topo IB signature motif; other site
755732006978	RteC protein; Region: RteC; pfam09357
755732006979	Helix-turn-helix domain; Region: HTH_17; pfam12728
755732006980	Helix-turn-helix domain; Region: HTH_36; pfam13730
755732006981	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732006982	Walker A/P-loop; other site
755732006983	ATP binding site [chemical binding]; other site
755732006984	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
755732006985	Predicted transporter component [General function prediction only]; Region: COG2391
755732006986	Sulphur transport; Region: Sulf_transp; pfam04143
755732006987	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
755732006988	Predicted transporter component [General function prediction only]; Region: COG2391
755732006989	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732006990	S-adenosylmethionine binding site [chemical binding]; other site
755732006991	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
755732006992	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006993	active site residue [active]
755732006994	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
755732006995	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
755732006996	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
755732006997	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732006998	active site residue [active]
755732006999	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732007000	active site residue [active]
755732007001	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732007002	active site residue [active]
755732007003	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732007004	catalytic residues [active]
755732007005	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732007006	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732007007	ligand binding site [chemical binding]; other site
755732007008	flexible hinge region; other site
755732007009	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
755732007010	putative switch regulator; other site
755732007011	non-specific DNA interactions [nucleotide binding]; other site
755732007012	DNA binding site [nucleotide binding]
755732007013	sequence specific DNA binding site [nucleotide binding]; other site
755732007014	putative cAMP binding site [chemical binding]; other site
755732007015	DsrE/DsrF-like family; Region: DrsE; cl00672
755732007016	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
755732007017	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
755732007018	active site
755732007019	metal binding site [ion binding]; metal-binding site
755732007020	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
755732007021	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732007022	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732007023	non-specific DNA binding site [nucleotide binding]; other site
755732007024	salt bridge; other site
755732007025	sequence-specific DNA binding site [nucleotide binding]; other site
755732007026	non-specific DNA binding site [nucleotide binding]; other site
755732007027	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
755732007028	salt bridge; other site
755732007029	sequence-specific DNA binding site [nucleotide binding]; other site
755732007030	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
755732007031	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732007032	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732007033	ATP binding site [chemical binding]; other site
755732007034	Mg2+ binding site [ion binding]; other site
755732007035	G-X-G motif; other site
755732007036	chromosome segregation protein; Provisional; Region: PRK03918
755732007037	TIGR02646 family protein; Region: TIGR02646
755732007038	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
755732007039	Methyltransferase domain; Region: Methyltransf_26; pfam13659
755732007040	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
755732007041	active site
755732007042	NTP binding site [chemical binding]; other site
755732007043	metal binding triad [ion binding]; metal-binding site
755732007044	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
755732007045	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732007046	Walker A motif; other site
755732007047	ATP binding site [chemical binding]; other site
755732007048	Walker B motif; other site
755732007049	arginine finger; other site
755732007050	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
755732007051	Transposase; Region: DDE_Tnp_ISL3; pfam01610
755732007052	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732007053	non-specific DNA binding site [nucleotide binding]; other site
755732007054	salt bridge; other site
755732007055	sequence-specific DNA binding site [nucleotide binding]; other site
755732007056	N-terminal putative catalytic domain of uncharacterized HKD family nucleases fused to putative helicases from the Snf2-like family; Region: PLDc_N_Snf2_like; cd09178
755732007057	PLD-like domain; Region: PLDc_2; pfam13091
755732007058	putative homodimer interface [polypeptide binding]; other site
755732007059	putative active site [active]
755732007060	catalytic site [active]
755732007061	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732007062	ATP binding site [chemical binding]; other site
755732007063	putative Mg++ binding site [ion binding]; other site
755732007064	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
755732007065	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732007066	nucleotide binding region [chemical binding]; other site
755732007067	ATP-binding site [chemical binding]; other site
755732007068	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
755732007069	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
755732007070	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
755732007071	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
755732007072	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732007073	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732007074	non-specific DNA binding site [nucleotide binding]; other site
755732007075	salt bridge; other site
755732007076	sequence-specific DNA binding site [nucleotide binding]; other site
755732007077	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007078	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007079	binding surface
755732007080	TPR motif; other site
755732007081	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007082	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007083	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732007084	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732007085	ATP binding site [chemical binding]; other site
755732007086	Mg2+ binding site [ion binding]; other site
755732007087	G-X-G motif; other site
755732007088	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732007089	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732007090	active site
755732007091	phosphorylation site [posttranslational modification]
755732007092	intermolecular recognition site; other site
755732007093	dimerization interface [polypeptide binding]; other site
755732007094	LytTr DNA-binding domain; Region: LytTR; smart00850
755732007095	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007096	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007097	binding surface
755732007098	TPR motif; other site
755732007099	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007100	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732007101	Histidine kinase; Region: HisKA_3; pfam07730
755732007102	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732007103	ATP binding site [chemical binding]; other site
755732007104	Mg2+ binding site [ion binding]; other site
755732007105	G-X-G motif; other site
755732007106	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732007107	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732007108	active site
755732007109	phosphorylation site [posttranslational modification]
755732007110	intermolecular recognition site; other site
755732007111	dimerization interface [polypeptide binding]; other site
755732007112	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732007113	DNA binding residues [nucleotide binding]
755732007114	dimerization interface [polypeptide binding]; other site
755732007115	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007116	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
755732007117	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
755732007118	Walker A/P-loop; other site
755732007119	ATP binding site [chemical binding]; other site
755732007120	Q-loop/lid; other site
755732007121	ABC transporter signature motif; other site
755732007122	Walker B; other site
755732007123	D-loop; other site
755732007124	H-loop/switch region; other site
755732007125	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
755732007126	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
755732007127	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732007128	dimerization interface [polypeptide binding]; other site
755732007129	putative DNA binding site [nucleotide binding]; other site
755732007130	putative Zn2+ binding site [ion binding]; other site
755732007131	Low molecular weight phosphatase family; Region: LMWPc; cl00105
755732007132	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
755732007133	arsenical-resistance protein; Region: acr3; TIGR00832
755732007134	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
755732007135	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
755732007136	metal ion-dependent adhesion site (MIDAS); other site
755732007137	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
755732007138	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732007139	CsbD-like; Region: CsbD; cl17424
755732007140	Entericidin EcnA/B family; Region: Entericidin; cl02322
755732007141	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
755732007142	YtxH-like protein; Region: YtxH; cl02079
755732007143	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732007144	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732007145	Cupin domain; Region: Cupin_2; cl17218
755732007146	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732007147	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732007148	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
755732007149	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732007150	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732007151	Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136
755732007152	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
755732007153	NAD(P) binding site [chemical binding]; other site
755732007154	catalytic residues [active]
755732007155	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
755732007156	Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; Region: KAZAL_FS; cd00104
755732007157	M28 Zn-Peptidases; Region: M28_like_1; cd05640
755732007158	Peptidase family M28; Region: Peptidase_M28; pfam04389
755732007159	metal binding site [ion binding]; metal-binding site
755732007160	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
755732007161	active site
755732007162	catalytic residues [active]
755732007163	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007164	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
755732007165	Putative ATP-dependant zinc protease; Region: Zn_protease; cl01682
755732007166	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
755732007167	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732007168	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_1; cd06251
755732007169	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
755732007170	putative active site [active]
755732007171	Zn binding site [ion binding]; other site
755732007172	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
755732007173	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732007174	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732007175	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732007176	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732007177	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
755732007178	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732007179	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732007180	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732007181	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732007182	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732007183	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732007184	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007185	binding surface
755732007186	TPR motif; other site
755732007187	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
755732007188	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732007189	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732007190	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732007191	ligand binding site [chemical binding]; other site
755732007192	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732007193	active site residue [active]
755732007194	TPR repeat; Region: TPR_11; pfam13414
755732007195	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007196	TPR motif; other site
755732007197	binding surface
755732007198	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732007199	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732007200	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732007201	ligand binding site [chemical binding]; other site
755732007202	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
755732007203	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732007204	S-adenosylmethionine binding site [chemical binding]; other site
755732007205	Protein of unknown function (DUF1569); Region: DUF1569; pfam07606
755732007206	Predicted amidohydrolase [General function prediction only]; Region: COG0388
755732007207	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
755732007208	putative active site [active]
755732007209	catalytic triad [active]
755732007210	putative dimer interface [polypeptide binding]; other site
755732007211	Preprotein binding site; other site
755732007212	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
755732007213	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
755732007214	synthetase active site [active]
755732007215	NTP binding site [chemical binding]; other site
755732007216	metal binding site [ion binding]; metal-binding site
755732007217	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732007218	Family description; Region: DsbD_2; pfam13386
755732007219	FixH; Region: FixH; pfam05751
755732007220	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
755732007221	4Fe-4S binding domain; Region: Fer4_5; pfam12801
755732007222	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
755732007223	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
755732007224	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
755732007225	Cytochrome c; Region: Cytochrom_C; pfam00034
755732007226	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
755732007227	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
755732007228	putative bifunctional cbb3-type cytochrome c oxidase subunit I/II; Provisional; Region: PRK14485
755732007229	Cytochrome cbb3 oxidase subunit I.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction...; Region: cbb3_Oxidase_I; cd01661
755732007230	Low-spin heme binding site [chemical binding]; other site
755732007231	Putative water exit pathway; other site
755732007232	Binuclear center (active site) [active]
755732007233	Putative proton exit pathway; other site
755732007234	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; pfam02433
755732007235	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
755732007236	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
755732007237	DEAD-like helicases superfamily; Region: DEXDc; smart00487
755732007238	ATP binding site [chemical binding]; other site
755732007239	putative Mg++ binding site [ion binding]; other site
755732007240	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732007241	nucleotide binding region [chemical binding]; other site
755732007242	ATP-binding site [chemical binding]; other site
755732007243	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
755732007244	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
755732007245	Heavy-metal-associated domain; Region: HMA; pfam00403
755732007246	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
755732007247	Soluble P-type ATPase [General function prediction only]; Region: COG4087
755732007248	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
755732007249	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732007250	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732007251	ligand binding site [chemical binding]; other site
755732007252	flexible hinge region; other site
755732007253	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
755732007254	putative switch regulator; other site
755732007255	non-specific DNA interactions [nucleotide binding]; other site
755732007256	DNA binding site [nucleotide binding]
755732007257	sequence specific DNA binding site [nucleotide binding]; other site
755732007258	putative cAMP binding site [chemical binding]; other site
755732007259	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
755732007260	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
755732007261	peptidase T; Region: peptidase-T; TIGR01882
755732007262	metal binding site [ion binding]; metal-binding site
755732007263	dimer interface [polypeptide binding]; other site
755732007264	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
755732007265	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
755732007266	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732007267	catalytic residue [active]
755732007268	shikimate kinase; Reviewed; Region: aroK; PRK00131
755732007269	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
755732007270	ADP binding site [chemical binding]; other site
755732007271	magnesium binding site [ion binding]; other site
755732007272	putative shikimate binding site; other site
755732007273	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
755732007274	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
755732007275	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732007276	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
755732007277	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
755732007278	Domain present in PSD-95, Dlg, and ZO-1/2; Region: PDZ; smart00228
755732007279	protein binding site [polypeptide binding]; other site
755732007280	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
755732007281	CRISPR/Cas system-associated protein Cas1; Region: Cas1_II; cd09720
755732007282	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
755732007283	Fic/DOC family; Region: Fic; pfam02661
755732007284	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
755732007285	CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI; Region: cas_Csn1; TIGR01865
755732007286	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
755732007287	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
755732007288	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
755732007289	RNA binding surface [nucleotide binding]; other site
755732007290	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
755732007291	probable active site [active]
755732007292	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
755732007293	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
755732007294	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007295	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
755732007296	hypothetical protein; Reviewed; Region: PRK00024
755732007297	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
755732007298	MPN+ (JAMM) motif; other site
755732007299	Zinc-binding site [ion binding]; other site
755732007300	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u7; cd10931
755732007301	putative active site [active]
755732007302	GSCFA family; Region: GSCFA; pfam08885
755732007303	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732007304	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732007305	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732007306	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732007307	DNA binding residues [nucleotide binding]
755732007308	malate dehydrogenase; Reviewed; Region: PRK06223
755732007309	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
755732007310	dimer interface [polypeptide binding]; other site
755732007311	NAD(P) binding site [chemical binding]; other site
755732007312	tetramer (dimer of dimers) interface [polypeptide binding]; other site
755732007313	substrate binding site [chemical binding]; other site
755732007314	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA; cl01007
755732007315	homopentamer interface [polypeptide binding]; other site
755732007316	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
755732007317	tol-pal system protein YbgF; Provisional; Region: PRK10803
755732007318	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
755732007319	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
755732007320	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
755732007321	substrate binding site [chemical binding]; other site
755732007322	oxyanion hole (OAH) forming residues; other site
755732007323	trimer interface [polypeptide binding]; other site
755732007324	mechanosensitive channel MscS; Provisional; Region: PRK10334
755732007325	Conserved TM helix; Region: TM_helix; pfam05552
755732007326	Mechanosensitive ion channel; Region: MS_channel; pfam00924
755732007327	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
755732007328	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
755732007329	CoenzymeA binding site [chemical binding]; other site
755732007330	subunit interaction site [polypeptide binding]; other site
755732007331	PHB binding site; other site
755732007332	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
755732007333	dihydropteroate synthase; Region: DHPS; TIGR01496
755732007334	substrate binding pocket [chemical binding]; other site
755732007335	dimer interface [polypeptide binding]; other site
755732007336	inhibitor binding site; inhibition site
755732007337	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
755732007338	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
755732007339	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732007340	triosephosphate isomerase; Provisional; Region: PRK14567
755732007341	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
755732007342	substrate binding site [chemical binding]; other site
755732007343	dimer interface [polypeptide binding]; other site
755732007344	catalytic triad [active]
755732007345	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
755732007346	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732007347	S-adenosylmethionine binding site [chemical binding]; other site
755732007348	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
755732007349	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007350	binding surface
755732007351	TPR repeat; Region: TPR_11; pfam13414
755732007352	TPR motif; other site
755732007353	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732007354	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
755732007355	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
755732007356	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
755732007357	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
755732007358	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732007359	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732007360	ligand binding site [chemical binding]; other site
755732007361	flexible hinge region; other site
755732007362	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732007363	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732007364	ligand binding site [chemical binding]; other site
755732007365	Rrf2 family protein; Region: rrf2_super; TIGR00738
755732007366	Transcriptional regulator; Region: Rrf2; pfam02082
755732007367	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
755732007368	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
755732007369	Low-spin heme binding site [chemical binding]; other site
755732007370	D-pathway; other site
755732007371	Putative water exit pathway; other site
755732007372	Binuclear center (active site) [active]
755732007373	K-pathway; other site
755732007374	Putative proton exit pathway; other site
755732007375	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
755732007376	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
755732007377	Cytochrome c; Region: Cytochrom_C; pfam00034
755732007378	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
755732007379	heme-binding site [chemical binding]; other site
755732007380	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
755732007381	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
755732007382	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
755732007383	Hemerythrin-like domain; Region: Hr-like; cd12108
755732007384	Beta-propeller repeat; Region: SBBP; pfam06739
755732007385	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
755732007386	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
755732007387	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
755732007388	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732007389	motif II; other site
755732007390	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
755732007391	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
755732007392	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
755732007393	Beta-Casp domain; Region: Beta-Casp; smart01027
755732007394	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
755732007395	ATP cone domain; Region: ATP-cone; pfam03477
755732007396	Restriction endonuclease; Region: Mrr_cat; pfam04471
755732007397	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732007398	Ligand Binding Site [chemical binding]; other site
755732007399	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732007400	Ligand Binding Site [chemical binding]; other site
755732007401	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
755732007402	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
755732007403	putative active site [active]
755732007404	heme pocket [chemical binding]; other site
755732007405	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732007406	dimer interface [polypeptide binding]; other site
755732007407	phosphorylation site [posttranslational modification]
755732007408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732007409	ATP binding site [chemical binding]; other site
755732007410	Mg2+ binding site [ion binding]; other site
755732007411	G-X-G motif; other site
755732007412	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
755732007413	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732007414	active site
755732007415	phosphorylation site [posttranslational modification]
755732007416	intermolecular recognition site; other site
755732007417	dimerization interface [polypeptide binding]; other site
755732007418	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732007419	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732007420	ligand binding site [chemical binding]; other site
755732007421	flexible hinge region; other site
755732007422	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
755732007423	putative switch regulator; other site
755732007424	non-specific DNA interactions [nucleotide binding]; other site
755732007425	DNA binding site [nucleotide binding]
755732007426	sequence specific DNA binding site [nucleotide binding]; other site
755732007427	putative cAMP binding site [chemical binding]; other site
755732007428	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
755732007429	putative substrate binding site [chemical binding]; other site
755732007430	putative ATP binding site [chemical binding]; other site
755732007431	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
755732007432	Outer membrane efflux protein; Region: OEP; pfam02321
755732007433	Outer membrane efflux protein; Region: OEP; pfam02321
755732007434	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732007435	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732007436	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007437	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732007438	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732007439	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
755732007440	N-terminal plug; other site
755732007441	ligand-binding site [chemical binding]; other site
755732007442	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
755732007443	YjeF-related protein N-terminus; Region: YjeF_N; cl00318
755732007444	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732007445	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732007446	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
755732007447	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007448	squalene/oxidosqualene cyclases; Region: squalene_cyclas; TIGR01787
755732007449	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
755732007450	Active site cavity [active]
755732007451	catalytic acid [active]
755732007452	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
755732007453	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
755732007454	substrate binding pocket [chemical binding]; other site
755732007455	chain length determination region; other site
755732007456	substrate-Mg2+ binding site; other site
755732007457	catalytic residues [active]
755732007458	aspartate-rich region 1; other site
755732007459	active site lid residues [active]
755732007460	aspartate-rich region 2; other site
755732007461	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
755732007462	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
755732007463	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
755732007464	diphosphomevalonate decarboxylase; Region: PLN02407
755732007465	diphosphomevalonate decarboxylase; Region: PLN02407
755732007466	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
755732007467	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
755732007468	homodimer interface [polypeptide binding]; other site
755732007469	catalytic residues [active]
755732007470	NAD binding site [chemical binding]; other site
755732007471	substrate binding pocket [chemical binding]; other site
755732007472	flexible flap; other site
755732007473	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
755732007474	phosphate binding site [ion binding]; other site
755732007475	squalene epoxidase; Provisional; Region: PTZ00367
755732007476	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
755732007477	active site lid residues [active]
755732007478	substrate binding pocket [chemical binding]; other site
755732007479	catalytic residues [active]
755732007480	substrate-Mg2+ binding site; other site
755732007481	aspartate-rich region 1; other site
755732007482	aspartate-rich region 2; other site
755732007483	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007484	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
755732007485	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732007486	Rifampin ADP-ribosyl transferase; Region: Arr-ms; pfam12120
755732007487	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732007488	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
755732007489	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
755732007490	nucleophilic elbow; other site
755732007491	catalytic site [active]
755732007492	catalytic triad; other site
755732007493	Predicted transcriptional regulators [Transcription]; Region: COG1733
755732007494	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
755732007495	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
755732007496	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
755732007497	catalytic residues [active]
755732007498	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
755732007499	dimer interface [polypeptide binding]; other site
755732007500	FMN binding site [chemical binding]; other site
755732007501	Predicted transcriptional regulators [Transcription]; Region: COG1733
755732007502	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
755732007503	SET domain; Region: SET; pfam00856
755732007504	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
755732007505	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732007506	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732007507	DNA binding residues [nucleotide binding]
755732007508	dimerization interface [polypeptide binding]; other site
755732007509	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
755732007510	Protein of unknown function (DUF3667); Region: DUF3667; pfam12412
755732007511	bis(5'-nucleosyl)-tetraphosphatase PrpE; Provisional; Region: PRK13625
755732007512	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
755732007513	active site
755732007514	metal binding site [ion binding]; metal-binding site
755732007515	Predicted proline hydroxylase [Posttranslational modification, protein turnover, chaperones]; Region: EGL-9; COG3751
755732007516	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
755732007517	Cupin domain; Region: Cupin_2; cl17218
755732007518	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732007519	salt bridge; other site
755732007520	non-specific DNA binding site [nucleotide binding]; other site
755732007521	sequence-specific DNA binding site [nucleotide binding]; other site
755732007522	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
755732007523	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732007524	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732007525	Coenzyme A binding pocket [chemical binding]; other site
755732007526	PAS fold; Region: PAS_3; pfam08447
755732007527	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732007528	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732007529	DNA binding residues [nucleotide binding]
755732007530	dimerization interface [polypeptide binding]; other site
755732007531	Domain of unknown function (DUF4269); Region: DUF4269; pfam14091
755732007532	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
755732007533	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
755732007534	active site residue [active]
755732007535	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
755732007536	active site residue [active]
755732007537	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
755732007538	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: LpqC; COG3509
755732007539	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007540	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
755732007541	TPR repeat; Region: TPR_11; pfam13414
755732007542	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
755732007543	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732007544	S-adenosylmethionine binding site [chemical binding]; other site
755732007545	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
755732007546	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
755732007547	putative active site [active]
755732007548	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
755732007549	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732007550	active site
755732007551	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
755732007552	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007553	binding surface
755732007554	TPR repeat; Region: TPR_11; pfam13414
755732007555	TPR motif; other site
755732007556	DNA gyrase subunit A; Validated; Region: PRK05560
755732007557	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
755732007558	CAP-like domain; other site
755732007559	active site
755732007560	primary dimer interface [polypeptide binding]; other site
755732007561	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
755732007562	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
755732007563	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
755732007564	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
755732007565	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
755732007566	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
755732007567	Clp amino terminal domain; Region: Clp_N; pfam02861
755732007568	Clp amino terminal domain; Region: Clp_N; pfam02861
755732007569	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732007570	Walker A motif; other site
755732007571	ATP binding site [chemical binding]; other site
755732007572	Walker B motif; other site
755732007573	arginine finger; other site
755732007574	UvrB/uvrC motif; Region: UVR; pfam02151
755732007575	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732007576	Walker A motif; other site
755732007577	ATP binding site [chemical binding]; other site
755732007578	Walker B motif; other site
755732007579	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
755732007580	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
755732007581	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
755732007582	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
755732007583	homodimer interface [polypeptide binding]; other site
755732007584	NADP binding site [chemical binding]; other site
755732007585	substrate binding site [chemical binding]; other site
755732007586	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
755732007587	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
755732007588	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
755732007589	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
755732007590	Flagellin N-methylase; Region: FliB; pfam03692
755732007591	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732007592	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
755732007593	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
755732007594	putative active site [active]
755732007595	Zn binding site [ion binding]; other site
755732007596	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
755732007597	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
755732007598	active site
755732007599	catalytic site [active]
755732007600	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
755732007601	putative rRNA binding site [nucleotide binding]; other site
755732007602	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
755732007603	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
755732007604	active site
755732007605	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
755732007606	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
755732007607	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
755732007608	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
755732007609	anti sigma factor interaction site; other site
755732007610	regulatory phosphorylation site [posttranslational modification]; other site
755732007611	ribonuclease Z; Region: RNase_Z; TIGR02651
755732007612	DinB superfamily; Region: DinB_2; pfam12867
755732007613	Protein of unknown function (DUF1572); Region: DUF1572; pfam07609
755732007614	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
755732007615	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
755732007616	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
755732007617	putative acyl-acceptor binding pocket; other site
755732007618	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
755732007619	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732007620	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732007621	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732007622	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
755732007623	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
755732007624	putative tRNA-binding site [nucleotide binding]; other site
755732007625	B3/4 domain; Region: B3_4; pfam03483
755732007626	tRNA synthetase B5 domain; Region: B5; smart00874
755732007627	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
755732007628	dimer interface [polypeptide binding]; other site
755732007629	motif 1; other site
755732007630	motif 3; other site
755732007631	motif 2; other site
755732007632	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
755732007633	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
755732007634	AAA domain; Region: AAA_26; pfam13500
755732007635	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
755732007636	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
755732007637	inhibitor-cofactor binding pocket; inhibition site
755732007638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732007639	catalytic residue [active]
755732007640	AhpC/TSA family; Region: AhpC-TSA; pfam00578
755732007641	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732007642	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007643	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732007644	RNA polymerase sigma-70 factor, TIGR02943 family; Region: Sig70_famx1
755732007645	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732007646	DNA binding residues [nucleotide binding]
755732007647	Predicted membrane protein [Function unknown]; Region: COG1289
755732007648	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
755732007649	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
755732007650	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007651	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
755732007652	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
755732007653	inhibitor-cofactor binding pocket; inhibition site
755732007654	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732007655	catalytic residue [active]
755732007656	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732007657	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732007658	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732007659	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
755732007660	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
755732007661	PYR/PP interface [polypeptide binding]; other site
755732007662	dimer interface [polypeptide binding]; other site
755732007663	TPP binding site [chemical binding]; other site
755732007664	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
755732007665	von Willebrand factor type A domain; Region: VWA_2; pfam13519
755732007666	metal ion-dependent adhesion site (MIDAS); other site
755732007667	transketolase; Reviewed; Region: PRK05899
755732007668	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
755732007669	TPP-binding site [chemical binding]; other site
755732007670	dimer interface [polypeptide binding]; other site
755732007671	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
755732007672	C-terminal domain of CHU protein family; Region: CHU_C; cl17875
755732007673	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
755732007674	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
755732007675	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
755732007676	Sporulation related domain; Region: SPOR; pfam05036
755732007677	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
755732007678	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
755732007679	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
755732007680	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
755732007681	catalytic motif [active]
755732007682	Zn binding site [ion binding]; other site
755732007683	RibD C-terminal domain; Region: RibD_C; pfam01872
755732007684	metabolite-proton symporter; Region: 2A0106; TIGR00883
755732007685	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
755732007686	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
755732007687	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
755732007688	NADH(P)-binding; Region: NAD_binding_10; pfam13460
755732007689	NAD binding site [chemical binding]; other site
755732007690	substrate binding site [chemical binding]; other site
755732007691	putative active site [active]
755732007692	Cupin domain; Region: Cupin_2; pfam07883
755732007693	Domain of unknown function (DUF4287); Region: DUF4287; pfam14117
755732007694	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
755732007695	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
755732007696	minor groove reading motif; other site
755732007697	helix-hairpin-helix signature motif; other site
755732007698	substrate binding pocket [chemical binding]; other site
755732007699	active site
755732007700	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
755732007701	tetramer interface [polypeptide binding]; other site
755732007702	TPP-binding site [chemical binding]; other site
755732007703	heterodimer interface [polypeptide binding]; other site
755732007704	phosphorylation loop region [posttranslational modification]
755732007705	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
755732007706	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
755732007707	PYR/PP interface [polypeptide binding]; other site
755732007708	dimer interface [polypeptide binding]; other site
755732007709	TPP binding site [chemical binding]; other site
755732007710	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
755732007711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732007712	PspC domain; Region: PspC; pfam04024
755732007713	Predicted transcriptional regulators [Transcription]; Region: COG1695
755732007714	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
755732007715	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
755732007716	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
755732007717	RNA binding site [nucleotide binding]; other site
755732007718	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
755732007719	RNA binding site [nucleotide binding]; other site
755732007720	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
755732007721	RNA binding site [nucleotide binding]; other site
755732007722	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
755732007723	RNA binding site [nucleotide binding]; other site
755732007724	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
755732007725	RNA binding site [nucleotide binding]; other site
755732007726	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
755732007727	RNA binding site [nucleotide binding]; other site
755732007728	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732007729	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732007730	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732007731	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
755732007732	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732007733	Predicted NAD/FAD-binding protein [General function prediction only]; Region: COG2907
755732007734	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732007735	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007736	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007737	Histidine kinase; Region: His_kinase; pfam06580
755732007738	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732007739	ATP binding site [chemical binding]; other site
755732007740	Mg2+ binding site [ion binding]; other site
755732007741	G-X-G motif; other site
755732007742	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732007743	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732007744	active site
755732007745	phosphorylation site [posttranslational modification]
755732007746	intermolecular recognition site; other site
755732007747	dimerization interface [polypeptide binding]; other site
755732007748	LytTr DNA-binding domain; Region: LytTR; smart00850
755732007749	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
755732007750	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
755732007751	FeS/SAM binding site; other site
755732007752	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
755732007753	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007754	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732007755	TPR motif; other site
755732007756	binding surface
755732007757	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007758	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732007759	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732007760	dimer interface [polypeptide binding]; other site
755732007761	phosphorylation site [posttranslational modification]
755732007762	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732007763	ATP binding site [chemical binding]; other site
755732007764	Mg2+ binding site [ion binding]; other site
755732007765	G-X-G motif; other site
755732007766	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732007767	active site
755732007768	phosphorylation site [posttranslational modification]
755732007769	intermolecular recognition site; other site
755732007770	dimerization interface [polypeptide binding]; other site
755732007771	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
755732007772	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732007773	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007774	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732007775	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
755732007776	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732007777	Cadherin repeat-like domain; Region: CA_like; cl15786
755732007778	Ca2+ binding site [ion binding]; other site
755732007779	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732007780	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
755732007781	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732007782	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732007783	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732007784	ligand binding site [chemical binding]; other site
755732007785	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732007786	Predicted membrane protein [Function unknown]; Region: COG4270
755732007787	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
755732007788	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732007789	Beta-lactamase; Region: Beta-lactamase; pfam00144
755732007790	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
755732007791	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732007792	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
755732007793	ATP-GRASP peptide maturase, grasp-with-spasm system; Region: GRASP_w_spasm; TIGR04192
755732007794	Protein of unknown function (DUF3761); Region: DUF3761; pfam12587
755732007795	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
755732007796	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
755732007797	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
755732007798	Pathogenicity locus; Region: Cdd1; pfam11731
755732007799	recombination protein RecR; Reviewed; Region: recR; PRK00076
755732007800	RecR protein; Region: RecR; pfam02132
755732007801	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
755732007802	putative active site [active]
755732007803	putative metal-binding site [ion binding]; other site
755732007804	tetramer interface [polypeptide binding]; other site
755732007805	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
755732007806	SmpB-tmRNA interface; other site
755732007807	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732007808	HSP70 interaction site [polypeptide binding]; other site
755732007809	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
755732007810	AMP binding site [chemical binding]; other site
755732007811	active site
755732007812	acyl-activating enzyme (AAE) consensus motif; other site
755732007813	CoA binding site [chemical binding]; other site
755732007814	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
755732007815	BNR repeat-like domain; Region: BNR_2; pfam13088
755732007816	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
755732007817	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
755732007818	putative acyl-acceptor binding pocket; other site
755732007819	recombination factor protein RarA; Reviewed; Region: PRK13342
755732007820	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732007821	Walker A motif; other site
755732007822	ATP binding site [chemical binding]; other site
755732007823	Walker B motif; other site
755732007824	arginine finger; other site
755732007825	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
755732007826	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
755732007827	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
755732007828	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
755732007829	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
755732007830	active site
755732007831	metal binding site [ion binding]; metal-binding site
755732007832	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
755732007833	mce related protein; Region: MCE; pfam02470
755732007834	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
755732007835	4Fe-4S binding domain; Region: Fer4_2; pfam12797
755732007836	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
755732007837	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
755732007838	Cysteine-rich domain; Region: CCG; pfam02754
755732007839	Cysteine-rich domain; Region: CCG; pfam02754
755732007840	Domain of unknown function (DUF4421); Region: DUF4421; pfam14391
755732007841	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
755732007842	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732007843	Methyltransferase domain; Region: Methyltransf_23; pfam13489
755732007844	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732007845	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
755732007846	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732007847	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732007848	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732007849	DNA binding residues [nucleotide binding]
755732007850	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
755732007851	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
755732007852	quinone interaction residues [chemical binding]; other site
755732007853	active site
755732007854	catalytic residues [active]
755732007855	FMN binding site [chemical binding]; other site
755732007856	substrate binding site [chemical binding]; other site
755732007857	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
755732007858	active site
755732007859	catalytic residues [active]
755732007860	metal binding site [ion binding]; metal-binding site
755732007861	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732007862	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
755732007863	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732007864	glyceraldehyde-3-phosphate dehydrogenase; Reviewed; Region: PRK08289
755732007865	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
755732007866	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
755732007867	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
755732007868	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732007869	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
755732007870	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732007871	DNA binding residues [nucleotide binding]
755732007872	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
755732007873	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
755732007874	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
755732007875	protein binding site [polypeptide binding]; other site
755732007876	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
755732007877	protein binding site [polypeptide binding]; other site
755732007878	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
755732007879	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
755732007880	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
755732007881	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
755732007882	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732007883	YceG-like family; Region: YceG; pfam02618
755732007884	proteins similar to Escherichia coli yceG; Region: yceG_like; cl17666
755732007885	dimerization interface [polypeptide binding]; other site
755732007886	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
755732007887	active site
755732007888	dimer interface [polypeptide binding]; other site
755732007889	catalytic nucleophile [active]
755732007890	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
755732007891	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
755732007892	MarR family; Region: MarR_2; cl17246
755732007893	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
755732007894	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732007895	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732007896	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732007897	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732007898	ATP binding site [chemical binding]; other site
755732007899	putative Mg++ binding site [ion binding]; other site
755732007900	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732007901	nucleotide binding region [chemical binding]; other site
755732007902	ATP-binding site [chemical binding]; other site
755732007903	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
755732007904	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
755732007905	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732007906	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732007907	Walker A/P-loop; other site
755732007908	ATP binding site [chemical binding]; other site
755732007909	Q-loop/lid; other site
755732007910	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732007911	ABC transporter signature motif; other site
755732007912	Walker B; other site
755732007913	ABC transporter; Region: ABC_tran_2; pfam12848
755732007914	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732007915	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
755732007916	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
755732007917	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
755732007918	metal binding site [ion binding]; metal-binding site
755732007919	dimer interface [polypeptide binding]; other site
755732007920	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732007921	Histidine kinase; Region: HisKA_2; pfam07568
755732007922	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
755732007923	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732007924	HSP70 interaction site [polypeptide binding]; other site
755732007925	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
755732007926	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732007927	HSP70 interaction site [polypeptide binding]; other site
755732007928	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732007929	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
755732007930	HSP70 interaction site [polypeptide binding]; other site
755732007931	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732007932	non-specific DNA binding site [nucleotide binding]; other site
755732007933	salt bridge; other site
755732007934	sequence-specific DNA binding site [nucleotide binding]; other site
755732007935	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
755732007936	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
755732007937	Conserved oligomeric complex COG6; Region: COG6; smart01087
755732007938	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
755732007939	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
755732007940	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732007941	Walker A/P-loop; other site
755732007942	ATP binding site [chemical binding]; other site
755732007943	Q-loop/lid; other site
755732007944	ABC transporter signature motif; other site
755732007945	Walker B; other site
755732007946	D-loop; other site
755732007947	H-loop/switch region; other site
755732007948	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
755732007949	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
755732007950	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
755732007951	NAD binding site [chemical binding]; other site
755732007952	Phe binding site; other site
755732007953	transcription antitermination factor NusB; Region: nusB; TIGR01951
755732007954	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
755732007955	Preprotein translocase subunit; Region: YajC; pfam02699
755732007956	acetyl-CoA C-acetyltransferase; Region: PLN02644
755732007957	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
755732007958	dimer interface [polypeptide binding]; other site
755732007959	active site
755732007960	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
755732007961	Protein of unknown function, DUF481; Region: DUF481; cl01213
755732007962	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
755732007963	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
755732007964	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
755732007965	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
755732007966	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
755732007967	active site
755732007968	Zn binding site [ion binding]; other site
755732007969	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
755732007970	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732007971	Coenzyme A binding pocket [chemical binding]; other site
755732007972	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
755732007973	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
755732007974	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
755732007975	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
755732007976	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
755732007977	Methyltransferase domain; Region: Methyltransf_18; pfam12847
755732007978	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
755732007979	HSP70 interaction site [polypeptide binding]; other site
755732007980	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
755732007981	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732007982	DNA binding residues [nucleotide binding]
755732007983	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
755732007984	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
755732007985	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
755732007986	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732007987	S-adenosylmethionine binding site [chemical binding]; other site
755732007988	dihydroorotase; Validated; Region: pyrC; PRK09357
755732007989	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
755732007990	active site
755732007991	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
755732007992	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
755732007993	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
755732007994	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
755732007995	Walker A/P-loop; other site
755732007996	ATP binding site [chemical binding]; other site
755732007997	Q-loop/lid; other site
755732007998	ABC transporter signature motif; other site
755732007999	Walker B; other site
755732008000	D-loop; other site
755732008001	H-loop/switch region; other site
755732008002	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
755732008003	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
755732008004	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
755732008005	dimerization interface [polypeptide binding]; other site
755732008006	active site
755732008007	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
755732008008	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
755732008009	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732008010	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
755732008011	Predicted permeases [General function prediction only]; Region: COG0795
755732008012	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
755732008013	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
755732008014	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
755732008015	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
755732008016	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008017	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
755732008018	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732008019	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732008020	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732008021	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
755732008022	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732008023	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732008024	ligand binding site [chemical binding]; other site
755732008025	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
755732008026	putative hydrophobic ligand binding site [chemical binding]; other site
755732008027	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
755732008028	Penicillinase repressor; Region: Pencillinase_R; pfam03965
755732008029	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732008030	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
755732008031	Ceramidase; Region: Ceramidase; pfam05875
755732008032	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
755732008033	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008034	Coenzyme A binding pocket [chemical binding]; other site
755732008035	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
755732008036	Domain of unknown function DUF20; Region: UPF0118; pfam01594
755732008037	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
755732008038	Ligand Binding Site [chemical binding]; other site
755732008039	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
755732008040	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
755732008041	homodimer interface [polypeptide binding]; other site
755732008042	substrate-cofactor binding pocket; other site
755732008043	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732008044	catalytic residue [active]
755732008045	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
755732008046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
755732008047	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
755732008048	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
755732008049	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
755732008050	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
755732008051	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
755732008052	substrate binding site [chemical binding]; other site
755732008053	hexamer interface [polypeptide binding]; other site
755732008054	metal binding site [ion binding]; metal-binding site
755732008055	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732008056	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732008057	ligand binding site [chemical binding]; other site
755732008058	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
755732008059	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
755732008060	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
755732008061	active site
755732008062	intersubunit interactions; other site
755732008063	catalytic residue [active]
755732008064	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
755732008065	Zn binding site [ion binding]; other site
755732008066	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732008067	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
755732008068	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
755732008069	putative active site [active]
755732008070	putative metal binding site [ion binding]; other site
755732008071	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732008072	Ligand Binding Site [chemical binding]; other site
755732008073	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
755732008074	Ligand Binding Site [chemical binding]; other site
755732008075	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
755732008076	S1 domain; Region: S1_2; pfam13509
755732008077	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732008078	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732008079	active site
755732008080	phosphorylation site [posttranslational modification]
755732008081	intermolecular recognition site; other site
755732008082	dimerization interface [polypeptide binding]; other site
755732008083	LytTr DNA-binding domain; Region: LytTR; smart00850
755732008084	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
755732008085	Histidine kinase; Region: His_kinase; pfam06580
755732008086	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732008087	Mg2+ binding site [ion binding]; other site
755732008088	CTP synthetase; Validated; Region: pyrG; PRK05380
755732008089	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
755732008090	Catalytic site [active]
755732008091	active site
755732008092	UTP binding site [chemical binding]; other site
755732008093	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
755732008094	active site
755732008095	putative oxyanion hole; other site
755732008096	catalytic triad [active]
755732008097	membrane protein insertase; Provisional; Region: PRK01318
755732008098	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
755732008099	SnoaL-like domain; Region: SnoaL_3; pfam13474
755732008100	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
755732008101	Peptidase S8 family domain in Subtilisin_Novo-like proteins; Region: Peptidases_S8_Subtilisin_Novo-like; cd07483
755732008102	active site
755732008103	catalytic triad [active]
755732008104	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
755732008105	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
755732008106	active site
755732008107	catalytic residues [active]
755732008108	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008109	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
755732008110	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
755732008111	active site
755732008112	Zn binding site [ion binding]; other site
755732008113	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
755732008114	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
755732008115	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
755732008116	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
755732008117	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
755732008118	dimer interface [polypeptide binding]; other site
755732008119	FMN binding site [chemical binding]; other site
755732008120	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
755732008121	catalytic motif [active]
755732008122	Catalytic residue [active]
755732008123	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732008124	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732008125	catalytic residues [active]
755732008126	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
755732008127	active site residue [active]
755732008128	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
755732008129	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732008130	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732008131	ligand binding site [chemical binding]; other site
755732008132	flexible hinge region; other site
755732008133	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
755732008134	putative switch regulator; other site
755732008135	non-specific DNA interactions [nucleotide binding]; other site
755732008136	DNA binding site [nucleotide binding]
755732008137	sequence specific DNA binding site [nucleotide binding]; other site
755732008138	putative cAMP binding site [chemical binding]; other site
755732008139	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
755732008140	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732008141	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
755732008142	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
755732008143	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
755732008144	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
755732008145	Beta-lactamase; Region: Beta-lactamase; cl17358
755732008146	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
755732008147	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
755732008148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732008149	ATP binding site [chemical binding]; other site
755732008150	Mg2+ binding site [ion binding]; other site
755732008151	G-X-G motif; other site
755732008152	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
755732008153	ATP binding site [chemical binding]; other site
755732008154	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
755732008155	Rhomboid family; Region: Rhomboid; pfam01694
755732008156	Rhomboid family; Region: Rhomboid; cl11446
755732008157	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
755732008158	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
755732008159	putative catalytic site [active]
755732008160	putative metal binding site [ion binding]; other site
755732008161	putative phosphate binding site [ion binding]; other site
755732008162	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
755732008163	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
755732008164	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
755732008165	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
755732008166	ATP binding site [chemical binding]; other site
755732008167	putative Mg++ binding site [ion binding]; other site
755732008168	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732008169	nucleotide binding region [chemical binding]; other site
755732008170	ATP-binding site [chemical binding]; other site
755732008171	DbpA RNA binding domain; Region: DbpA; pfam03880
755732008172	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
755732008173	active site
755732008174	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
755732008175	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
755732008176	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
755732008177	Protein of unknown function (DUF2614); Region: DUF2614; cl07936
755732008178	Methyltransferase domain; Region: Methyltransf_24; pfam13578
755732008179	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
755732008180	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR1; cd08267
755732008181	putative NAD(P) binding site [chemical binding]; other site
755732008182	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
755732008183	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
755732008184	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
755732008185	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
755732008186	metal binding site [ion binding]; metal-binding site
755732008187	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
755732008188	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
755732008189	substrate binding site [chemical binding]; other site
755732008190	glutamase interaction surface [polypeptide binding]; other site
755732008191	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
755732008192	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
755732008193	catalytic residues [active]
755732008194	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
755732008195	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
755732008196	putative active site [active]
755732008197	oxyanion strand; other site
755732008198	catalytic triad [active]
755732008199	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
755732008200	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732008201	active site
755732008202	motif I; other site
755732008203	motif II; other site
755732008204	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
755732008205	putative active site pocket [active]
755732008206	4-fold oligomerization interface [polypeptide binding]; other site
755732008207	metal binding residues [ion binding]; metal-binding site
755732008208	3-fold/trimer interface [polypeptide binding]; other site
755732008209	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
755732008210	histidinol dehydrogenase; Region: hisD; TIGR00069
755732008211	NAD binding site [chemical binding]; other site
755732008212	dimerization interface [polypeptide binding]; other site
755732008213	product binding site; other site
755732008214	substrate binding site [chemical binding]; other site
755732008215	zinc binding site [ion binding]; other site
755732008216	catalytic residues [active]
755732008217	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
755732008218	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
755732008219	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732008220	homodimer interface [polypeptide binding]; other site
755732008221	catalytic residue [active]
755732008222	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
755732008223	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
755732008224	substrate binding pocket [chemical binding]; other site
755732008225	membrane-bound complex binding site; other site
755732008226	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
755732008227	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
755732008228	dimer interface [polypeptide binding]; other site
755732008229	allosteric magnesium binding site [ion binding]; other site
755732008230	active site
755732008231	aspartate-rich active site metal binding site; other site
755732008232	Schiff base residues; other site
755732008233	Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; Region: ABCG_EPDR; cd03213
755732008234	phosphonate ABC transporter, ATP-binding protein; Region: ABC_phnC; TIGR02315
755732008235	Walker A/P-loop; other site
755732008236	ATP binding site [chemical binding]; other site
755732008237	Q-loop/lid; other site
755732008238	ABC transporter signature motif; other site
755732008239	Walker B; other site
755732008240	D-loop; other site
755732008241	H-loop/switch region; other site
755732008242	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
755732008243	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
755732008244	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
755732008245	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
755732008246	NAD(P) binding site [chemical binding]; other site
755732008247	homotetramer interface [polypeptide binding]; other site
755732008248	homodimer interface [polypeptide binding]; other site
755732008249	active site
755732008250	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
755732008251	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
755732008252	prolyl-tRNA synthetase; Provisional; Region: PRK08661
755732008253	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
755732008254	dimer interface [polypeptide binding]; other site
755732008255	motif 1; other site
755732008256	active site
755732008257	motif 2; other site
755732008258	motif 3; other site
755732008259	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
755732008260	anticodon binding site; other site
755732008261	zinc-binding site [ion binding]; other site
755732008262	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
755732008263	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
755732008264	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
755732008265	NAD(P) binding site [chemical binding]; other site
755732008266	4Fe-4S binding domain; Region: Fer4; pfam00037
755732008267	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
755732008268	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
755732008269	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
755732008270	P-loop; other site
755732008271	Magnesium ion binding site [ion binding]; other site
755732008272	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
755732008273	Magnesium ion binding site [ion binding]; other site
755732008274	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
755732008275	ParB-like nuclease domain; Region: ParBc; pfam02195
755732008276	dihydrodipicolinate reductase; Provisional; Region: PRK00048
755732008277	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
755732008278	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
755732008279	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
755732008280	Catalytic site [active]
755732008281	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
755732008282	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
755732008283	WbqC-like protein family; Region: WbqC; pfam08889
755732008284	WbqC-like protein family; Region: WbqC; pfam08889
755732008285	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
755732008286	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
755732008287	homodimer interface [polypeptide binding]; other site
755732008288	substrate-cofactor binding pocket; other site
755732008289	catalytic residue [active]
755732008290	DEAD-like helicases superfamily; Region: DEXDc; smart00487
755732008291	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732008292	ATP binding site [chemical binding]; other site
755732008293	putative Mg++ binding site [ion binding]; other site
755732008294	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732008295	nucleotide binding region [chemical binding]; other site
755732008296	ATP-binding site [chemical binding]; other site
755732008297	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732008298	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732008299	non-specific DNA binding site [nucleotide binding]; other site
755732008300	salt bridge; other site
755732008301	sequence-specific DNA binding site [nucleotide binding]; other site
755732008302	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
755732008303	Catalytic site [active]
755732008304	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
755732008305	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
755732008306	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732008307	Walker A/P-loop; other site
755732008308	ATP binding site [chemical binding]; other site
755732008309	Q-loop/lid; other site
755732008310	ABC transporter signature motif; other site
755732008311	Walker B; other site
755732008312	D-loop; other site
755732008313	H-loop/switch region; other site
755732008314	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
755732008315	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
755732008316	putative RNA binding site [nucleotide binding]; other site
755732008317	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732008318	S-adenosylmethionine binding site [chemical binding]; other site
755732008319	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
755732008320	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
755732008321	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
755732008322	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
755732008323	putative active site [active]
755732008324	substrate binding site [chemical binding]; other site
755732008325	putative cosubstrate binding site; other site
755732008326	catalytic site [active]
755732008327	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
755732008328	substrate binding site [chemical binding]; other site
755732008329	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
755732008330	IHF - DNA interface [nucleotide binding]; other site
755732008331	IHF dimer interface [polypeptide binding]; other site
755732008332	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008333	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008334	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
755732008335	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
755732008336	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
755732008337	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732008338	catalytic residue [active]
755732008339	Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303
755732008340	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
755732008341	putative ligand binding site [chemical binding]; other site
755732008342	NAD binding site [chemical binding]; other site
755732008343	dimerization interface [polypeptide binding]; other site
755732008344	catalytic site [active]
755732008345	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
755732008346	Uncharacterized conserved protein [Function unknown]; Region: COG4198
755732008347	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
755732008348	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
755732008349	catalytic residue [active]
755732008350	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
755732008351	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
755732008352	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008353	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
755732008354	active site
755732008355	catalytic triad [active]
755732008356	oxyanion hole [active]
755732008357	Peptidase family M49; Region: Peptidase_M49; pfam03571
755732008358	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
755732008359	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732008360	Protein of unknown function, DUF479; Region: DUF479; cl01203
755732008361	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
755732008362	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
755732008363	substrate binding pocket [chemical binding]; other site
755732008364	membrane-bound complex binding site; other site
755732008365	hinge residues; other site
755732008366	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
755732008367	N-acetyl-D-glucosamine binding site [chemical binding]; other site
755732008368	catalytic residue [active]
755732008369	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
755732008370	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
755732008371	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732008372	Walker A/P-loop; other site
755732008373	ATP binding site [chemical binding]; other site
755732008374	ABC transporter; Region: ABC_tran; pfam00005
755732008375	Q-loop/lid; other site
755732008376	ABC transporter signature motif; other site
755732008377	Walker B; other site
755732008378	D-loop; other site
755732008379	H-loop/switch region; other site
755732008380	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
755732008381	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
755732008382	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
755732008383	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
755732008384	catalytic residues [active]
755732008385	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008386	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
755732008387	Saccharopine Dehydrogenase like proteins; Region: SDH_like; cd05199
755732008388	active site
755732008389	ligand binding site [chemical binding]; other site
755732008390	NAD(P) binding site [chemical binding]; other site
755732008391	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
755732008392	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
755732008393	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
755732008394	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
755732008395	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
755732008396	phosphate binding site [ion binding]; other site
755732008397	FOG: CBS domain [General function prediction only]; Region: COG0517
755732008398	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
755732008399	Protein of unknown function, DUF393; Region: DUF393; cl01136
755732008400	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
755732008401	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
755732008402	conserved cys residue [active]
755732008403	MutS domain III; Region: MutS_III; pfam05192
755732008404	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732008405	Walker A/P-loop; other site
755732008406	ATP binding site [chemical binding]; other site
755732008407	Q-loop/lid; other site
755732008408	ABC transporter signature motif; other site
755732008409	Walker B; other site
755732008410	D-loop; other site
755732008411	H-loop/switch region; other site
755732008412	esterase, PHB depolymerase family; Region: esterase_phb; TIGR01840
755732008413	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732008414	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
755732008415	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
755732008416	active site
755732008417	substrate-binding site [chemical binding]; other site
755732008418	metal-binding site [ion binding]
755732008419	ATP binding site [chemical binding]; other site
755732008420	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
755732008421	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732008422	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732008423	ligand binding site [chemical binding]; other site
755732008424	flexible hinge region; other site
755732008425	Uncharacterized conserved protein [Function unknown]; Region: COG2128
755732008426	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
755732008427	RNA polymerase sigma factor; Provisional; Region: PRK12513
755732008428	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732008429	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732008430	DNA binding residues [nucleotide binding]
755732008431	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
755732008432	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
755732008433	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
755732008434	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732008435	Walker A/P-loop; other site
755732008436	ATP binding site [chemical binding]; other site
755732008437	Q-loop/lid; other site
755732008438	ABC transporter signature motif; other site
755732008439	Walker B; other site
755732008440	D-loop; other site
755732008441	H-loop/switch region; other site
755732008442	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
755732008443	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
755732008444	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
755732008445	transcription termination factor Rho; Provisional; Region: PRK12608
755732008446	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
755732008447	RNA binding site [nucleotide binding]; other site
755732008448	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
755732008449	multimer interface [polypeptide binding]; other site
755732008450	Walker A motif; other site
755732008451	ATP binding site [chemical binding]; other site
755732008452	Walker B motif; other site
755732008453	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
755732008454	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
755732008455	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
755732008456	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
755732008457	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
755732008458	hypothetical protein; Provisional; Region: PRK12472
755732008459	MAEBL; Provisional; Region: PTZ00121
755732008460	hydroxyglutarate oxidase; Provisional; Region: PRK11728
755732008461	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
755732008462	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
755732008463	elongation factor P; Validated; Region: PRK00529
755732008464	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
755732008465	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
755732008466	RNA binding site [nucleotide binding]; other site
755732008467	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
755732008468	RNA binding site [nucleotide binding]; other site
755732008469	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732008470	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
755732008471	spermidine synthase; Provisional; Region: PRK00811
755732008472	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732008473	S-adenosylmethionine binding site [chemical binding]; other site
755732008474	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
755732008475	putative active site [active]
755732008476	Mn binding site [ion binding]; other site
755732008477	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732008478	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732008479	flagellar motor protein MotD; Reviewed; Region: PRK09038
755732008480	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
755732008481	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
755732008482	NlpC/P60 family; Region: NLPC_P60; pfam00877
755732008483	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732008484	C-terminal peptidase (prc); Region: prc; TIGR00225
755732008485	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
755732008486	protein binding site [polypeptide binding]; other site
755732008487	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
755732008488	Catalytic dyad [active]
755732008489	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
755732008490	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
755732008491	GMP synthase subunit A; Validated; Region: PRK00758
755732008492	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
755732008493	conserved cys residue [active]
755732008494	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
755732008495	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
755732008496	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
755732008497	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008498	Coenzyme A binding pocket [chemical binding]; other site
755732008499	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
755732008500	Smr domain; Region: Smr; pfam01713
755732008501	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
755732008502	active site
755732008503	FOG: WD40 repeat [General function prediction only]; Region: COG2319
755732008504	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
755732008505	structural tetrad; other site
755732008506	(2R)-phospho-3-sulfolactate synthase (ComA); Region: ComA; pfam02679
755732008507	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
755732008508	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008509	TPR motif; other site
755732008510	binding surface
755732008511	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008512	binding surface
755732008513	TPR motif; other site
755732008514	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008515	binding surface
755732008516	TPR motif; other site
755732008517	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008518	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008519	binding surface
755732008520	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732008521	TPR motif; other site
755732008522	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
755732008523	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
755732008524	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
755732008525	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732008526	active site
755732008527	phosphorylation site [posttranslational modification]
755732008528	intermolecular recognition site; other site
755732008529	dimerization interface [polypeptide binding]; other site
755732008530	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732008531	DNA binding site [nucleotide binding]
755732008532	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
755732008533	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732008534	dimer interface [polypeptide binding]; other site
755732008535	phosphorylation site [posttranslational modification]
755732008536	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732008537	ATP binding site [chemical binding]; other site
755732008538	Mg2+ binding site [ion binding]; other site
755732008539	G-X-G motif; other site
755732008540	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
755732008541	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
755732008542	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
755732008543	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
755732008544	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
755732008545	KWG Leptospira; Region: KWG; pfam07656
755732008546	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732008547	TspO/MBR family; Region: TspO_MBR; pfam03073
755732008548	Cna protein B-type domain; Region: Cna_B_2; pfam13715
755732008549	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
755732008550	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
755732008551	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008552	binding surface
755732008553	TPR motif; other site
755732008554	Domain of unknown function (DUF4331); Region: DUF4331; pfam14224
755732008555	Domain of unknown function (DUF4331); Region: DUF4331; pfam14224
755732008556	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008557	Domain of unknown function (DUF4331); Region: DUF4331; pfam14224
755732008558	Domain of unknown function (DUF4331); Region: DUF4331; pfam14224
755732008559	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
755732008560	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
755732008561	Leucine rich repeat; Region: LRR_8; pfam13855
755732008562	Leucine rich repeat; Region: LRR_8; pfam13855
755732008563	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4339
755732008564	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008565	Coenzyme A binding pocket [chemical binding]; other site
755732008566	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
755732008567	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
755732008568	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
755732008569	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
755732008570	SnoaL-like domain; Region: SnoaL_2; pfam12680
755732008571	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
755732008572	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
755732008573	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008574	Coenzyme A binding pocket [chemical binding]; other site
755732008575	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
755732008576	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
755732008577	Walker A/P-loop; other site
755732008578	ATP binding site [chemical binding]; other site
755732008579	Q-loop/lid; other site
755732008580	ABC transporter signature motif; other site
755732008581	Walker B; other site
755732008582	D-loop; other site
755732008583	H-loop/switch region; other site
755732008584	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
755732008585	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
755732008586	FtsX-like permease family; Region: FtsX; pfam02687
755732008587	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732008588	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732008589	Cupin domain; Region: Cupin_2; cl17218
755732008590	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
755732008591	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
755732008592	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008593	Transposase; Region: DEDD_Tnp_IS110; pfam01548
755732008594	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
755732008595	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
755732008596	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
755732008597	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
755732008598	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
755732008599	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
755732008600	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008601	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
755732008602	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
755732008603	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
755732008604	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
755732008605	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732008606	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732008607	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732008608	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732008609	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
755732008610	Cupin domain; Region: Cupin_2; cl17218
755732008611	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
755732008612	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
755732008613	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
755732008614	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
755732008615	dimerization interface [polypeptide binding]; other site
755732008616	DPS ferroxidase diiron center [ion binding]; other site
755732008617	ion pore; other site
755732008618	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
755732008619	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
755732008620	NAD(P) binding site [chemical binding]; other site
755732008621	active site
755732008622	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732008623	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732008624	ligand binding site [chemical binding]; other site
755732008625	Protein of unknown function (DUF511); Region: DUF511; cl01114
755732008626	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
755732008627	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
755732008628	Multicopper oxidase; Region: Cu-oxidase; pfam00394
755732008629	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
755732008630	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
755732008631	metal-binding site [ion binding]
755732008632	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
755732008633	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
755732008634	metal-binding site [ion binding]
755732008635	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
755732008636	metal-binding site [ion binding]
755732008637	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
755732008638	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
755732008639	metal-binding site [ion binding]
755732008640	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
755732008641	Soluble P-type ATPase [General function prediction only]; Region: COG4087
755732008642	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732008643	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732008644	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008645	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008646	Peptidase C10 family; Region: Peptidase_C10; pfam01640
755732008647	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
755732008648	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
755732008649	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
755732008650	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008651	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732008652	Predicted transcriptional regulators [Transcription]; Region: COG1510
755732008653	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732008654	putative DNA binding site [nucleotide binding]; other site
755732008655	putative Zn2+ binding site [ion binding]; other site
755732008656	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
755732008657	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732008658	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732008659	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732008660	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732008661	Protein export membrane protein; Region: SecD_SecF; cl14618
755732008662	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
755732008663	Protein of unknown function (DUF3137); Region: DUF3137; pfam11335
755732008664	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
755732008665	active site
755732008666	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008667	binding surface
755732008668	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732008669	TPR motif; other site
755732008670	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732008671	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732008672	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732008673	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008674	binding surface
755732008675	TPR motif; other site
755732008676	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732008677	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008678	binding surface
755732008679	TPR motif; other site
755732008680	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732008681	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732008682	dimer interface [polypeptide binding]; other site
755732008683	phosphorylation site [posttranslational modification]
755732008684	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732008685	ATP binding site [chemical binding]; other site
755732008686	Mg2+ binding site [ion binding]; other site
755732008687	G-X-G motif; other site
755732008688	Response regulator receiver domain; Region: Response_reg; pfam00072
755732008689	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732008690	active site
755732008691	phosphorylation site [posttranslational modification]
755732008692	intermolecular recognition site; other site
755732008693	dimerization interface [polypeptide binding]; other site
755732008694	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
755732008695	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732008696	Protein of unknown function (DUF4256); Region: DUF4256; pfam14066
755732008697	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
755732008698	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
755732008699	DoxX-like family; Region: DoxX_2; pfam13564
755732008700	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
755732008701	hydrophobic ligand binding site; other site
755732008702	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732008703	dimerization interface [polypeptide binding]; other site
755732008704	putative DNA binding site [nucleotide binding]; other site
755732008705	putative Zn2+ binding site [ion binding]; other site
755732008706	B12 binding domain; Region: B12-binding; pfam02310
755732008707	B12 binding site [chemical binding]; other site
755732008708	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
755732008709	GxxExxY protein; Region: GxxExxY; TIGR04256
755732008710	PAS domain; Region: PAS_9; pfam13426
755732008711	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732008712	Histidine kinase; Region: HisKA_2; pfam07568
755732008713	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732008714	ATP binding site [chemical binding]; other site
755732008715	Mg2+ binding site [ion binding]; other site
755732008716	G-X-G motif; other site
755732008717	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
755732008718	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732008719	non-specific DNA binding site [nucleotide binding]; other site
755732008720	salt bridge; other site
755732008721	sequence-specific DNA binding site [nucleotide binding]; other site
755732008722	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
755732008723	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
755732008724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
755732008725	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
755732008726	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
755732008727	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
755732008728	HTH domain; Region: HTH_11; pfam08279
755732008729	WYL domain; Region: WYL; pfam13280
755732008730	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732008731	S-adenosylmethionine binding site [chemical binding]; other site
755732008732	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
755732008733	DNA-binding interface [nucleotide binding]; DNA binding site
755732008734	Winged helix-turn helix; Region: HTH_29; pfam13551
755732008735	Transposase; Region: DEDD_Tnp_IS110; pfam01548
755732008736	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
755732008737	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
755732008738	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
755732008739	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cl00218
755732008740	Mechanosensitive ion channel; Region: MS_channel; pfam00924
755732008741	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
755732008742	Fic/DOC family; Region: Fic; pfam02661
755732008743	T5orf172 domain; Region: T5orf172; pfam10544
755732008744	DEAD-like helicases superfamily; Region: DEXDc; smart00487
755732008745	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
755732008746	ATP binding site [chemical binding]; other site
755732008747	putative Mg++ binding site [ion binding]; other site
755732008748	Virulence protein [General function prediction only]; Region: COG3943
755732008749	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
755732008750	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732008751	AAA domain; Region: AAA_13; pfam13166
755732008752	Walker A/P-loop; other site
755732008753	ATP binding site [chemical binding]; other site
755732008754	Q-loop/lid; other site
755732008755	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732008756	ABC transporter signature motif; other site
755732008757	Walker B; other site
755732008758	D-loop; other site
755732008759	H-loop/switch region; other site
755732008760	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
755732008761	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
755732008762	non-specific DNA binding site [nucleotide binding]; other site
755732008763	salt bridge; other site
755732008764	sequence-specific DNA binding site [nucleotide binding]; other site
755732008765	PIF1-like helicase; Region: PIF1; pfam05970
755732008766	AAA domain; Region: AAA_30; pfam13604
755732008767	Family description; Region: UvrD_C_2; pfam13538
755732008768	FG-GAP repeat; Region: FG-GAP; cl15299
755732008769	integron integrase; Region: integrase_gron; TIGR02249
755732008770	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
755732008771	active site
755732008772	DNA binding site [nucleotide binding]
755732008773	Int/Topo IB signature motif; other site
755732008774	Uncharacterized conserved protein [Function unknown]; Region: COG2968
755732008775	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
755732008776	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
755732008777	Active site serine [active]
755732008778	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
755732008779	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
755732008780	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
755732008781	G1 box; other site
755732008782	putative GEF interaction site [polypeptide binding]; other site
755732008783	GTP/Mg2+ binding site [chemical binding]; other site
755732008784	Switch I region; other site
755732008785	G2 box; other site
755732008786	G3 box; other site
755732008787	Switch II region; other site
755732008788	G4 box; other site
755732008789	G5 box; other site
755732008790	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
755732008791	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
755732008792	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
755732008793	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
755732008794	ATP binding site [chemical binding]; other site
755732008795	Mg++ binding site [ion binding]; other site
755732008796	motif III; other site
755732008797	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
755732008798	nucleotide binding region [chemical binding]; other site
755732008799	ATP-binding site [chemical binding]; other site
755732008800	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
755732008801	RNA binding site [nucleotide binding]; other site
755732008802	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
755732008803	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
755732008804	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
755732008805	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008806	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
755732008807	Helix-turn-helix domain; Region: HTH_18; pfam12833
755732008808	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
755732008809	Siderophore-interacting FAD-binding domain; Region: FAD_binding_9; pfam08021
755732008810	DinB superfamily; Region: DinB_2; pfam12867
755732008811	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
755732008812	active site flap/lid [active]
755732008813	nucleophilic elbow; other site
755732008814	catalytic triad [active]
755732008815	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
755732008816	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008817	Coenzyme A binding pocket [chemical binding]; other site
755732008818	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
755732008819	Leucine rich repeat; Region: LRR_8; pfam13855
755732008820	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
755732008821	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
755732008822	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732008823	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
755732008824	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732008825	DNA binding residues [nucleotide binding]
755732008826	dimerization interface [polypeptide binding]; other site
755732008827	Methyltransferase domain; Region: Methyltransf_11; pfam08241
755732008828	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
755732008829	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
755732008830	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732008831	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
755732008832	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
755732008833	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
755732008834	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
755732008835	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
755732008836	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732008837	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
755732008838	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
755732008839	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
755732008840	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
755732008841	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732008842	GxxExxY protein; Region: GxxExxY; TIGR04256
755732008843	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
755732008844	catalytic motif [active]
755732008845	Catalytic residue [active]
755732008846	DoxX-like family; Region: DoxX_2; pfam13564
755732008847	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
755732008848	catalytic residues [active]
755732008849	dimethylhistidine N-methyltransferase; Region: egtD_ergothio; TIGR03438
755732008850	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
755732008851	Uncharacterized conserved protein (DUF2260); Region: DUF2260; pfam10017
755732008852	ergothioneine biosynthesis protein EgtB; Region: egtB_TIGR03440
755732008853	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
755732008854	Domain of unknown function (DUF427); Region: DUF427; pfam04248
755732008855	Domain of unknown function (DUF427); Region: DUF427; pfam04248
755732008856	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732008857	Pirin-related protein [General function prediction only]; Region: COG1741
755732008858	Pirin; Region: Pirin; pfam02678
755732008859	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
755732008860	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008861	Coenzyme A binding pocket [chemical binding]; other site
755732008862	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; smart00782
755732008863	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
755732008864	PhnA protein; Region: PhnA; pfam03831
755732008865	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
755732008866	Interdomain contacts; other site
755732008867	Cytokine receptor motif; other site
755732008868	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; cl15433
755732008869	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008870	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
755732008871	Cysteine-rich CWC; Region: Cys_rich_CWC; pfam14375
755732008872	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
755732008873	Outer membrane efflux protein; Region: OEP; pfam02321
755732008874	Outer membrane efflux protein; Region: OEP; pfam02321
755732008875	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732008876	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732008877	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_4; cd08897
755732008878	putative hydrophobic ligand binding site [chemical binding]; other site
755732008879	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
755732008880	putative hydrophobic ligand binding site [chemical binding]; other site
755732008881	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
755732008882	putative hydrophobic ligand binding site [chemical binding]; other site
755732008883	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
755732008884	dimer interface [polypeptide binding]; other site
755732008885	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
755732008886	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732008887	dimerization interface [polypeptide binding]; other site
755732008888	putative DNA binding site [nucleotide binding]; other site
755732008889	putative Zn2+ binding site [ion binding]; other site
755732008890	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
755732008891	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
755732008892	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
755732008893	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
755732008894	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732008895	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
755732008896	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732008897	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
755732008898	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u2; cd11494
755732008899	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
755732008900	Na binding site [ion binding]; other site
755732008901	YcxB-like protein; Region: YcxB; pfam14317
755732008902	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
755732008903	EamA-like transporter family; Region: EamA; pfam00892
755732008904	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
755732008905	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
755732008906	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
755732008907	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
755732008908	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
755732008909	dimerization interface [polypeptide binding]; other site
755732008910	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732008911	dimer interface [polypeptide binding]; other site
755732008912	phosphorylation site [posttranslational modification]
755732008913	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732008914	ATP binding site [chemical binding]; other site
755732008915	G-X-G motif; other site
755732008916	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
755732008917	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732008918	active site
755732008919	phosphorylation site [posttranslational modification]
755732008920	intermolecular recognition site; other site
755732008921	dimerization interface [polypeptide binding]; other site
755732008922	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
755732008923	DNA binding site [nucleotide binding]
755732008924	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
755732008925	dimerization interface [polypeptide binding]; other site
755732008926	putative DNA binding site [nucleotide binding]; other site
755732008927	putative Zn2+ binding site [ion binding]; other site
755732008928	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
755732008929	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
755732008930	active site
755732008931	NTP binding site [chemical binding]; other site
755732008932	metal binding triad [ion binding]; metal-binding site
755732008933	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
755732008934	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
755732008935	Zn2+ binding site [ion binding]; other site
755732008936	Mg2+ binding site [ion binding]; other site
755732008937	Methyltransferase domain; Region: Methyltransf_23; pfam13489
755732008938	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732008939	S-adenosylmethionine binding site [chemical binding]; other site
755732008940	TraB family; Region: TraB; pfam01963
755732008941	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732008942	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
755732008943	CoA binding domain; Region: CoA_binding; smart00881
755732008944	CoA-ligase; Region: Ligase_CoA; pfam00549
755732008945	Inward rectifier potassium channel; Region: IRK; pfam01007
755732008946	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
755732008947	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
755732008948	Tetratricopeptide repeat; Region: TPR_16; pfam13432
755732008949	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732008950	TPR motif; other site
755732008951	binding surface
755732008952	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732008953	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
755732008954	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732008955	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732008956	ligand binding site [chemical binding]; other site
755732008957	UbiA prenyltransferase family; Region: UbiA; pfam01040
755732008958	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
755732008959	Maf-like protein; Region: Maf; pfam02545
755732008960	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
755732008961	active site
755732008962	dimer interface [polypeptide binding]; other site
755732008963	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732008964	Peptide-N-glycosidase F, C terminal; Region: N-glycanase_C; pfam09113
755732008965	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732008966	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
755732008967	active site
755732008968	Zn binding site [ion binding]; other site
755732008969	Predicted transcriptional regulators [Transcription]; Region: COG1733
755732008970	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
755732008971	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
755732008972	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
755732008973	NADP binding site [chemical binding]; other site
755732008974	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
755732008975	Domain of unknown function (DUF1990); Region: DUF1990; cl01969
755732008976	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
755732008977	putative catalytic site [active]
755732008978	putative phosphate binding site [ion binding]; other site
755732008979	putative metal binding site [ion binding]; other site
755732008980	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732008981	Coenzyme A binding pocket [chemical binding]; other site
755732008982	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
755732008983	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
755732008984	putative active site [active]
755732008985	heme pocket [chemical binding]; other site
755732008986	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
755732008987	dimer interface [polypeptide binding]; other site
755732008988	phosphorylation site [posttranslational modification]
755732008989	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732008990	ATP binding site [chemical binding]; other site
755732008991	Mg2+ binding site [ion binding]; other site
755732008992	G-X-G motif; other site
755732008993	Response regulator receiver domain; Region: Response_reg; pfam00072
755732008994	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732008995	active site
755732008996	phosphorylation site [posttranslational modification]
755732008997	intermolecular recognition site; other site
755732008998	dimerization interface [polypeptide binding]; other site
755732008999	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
755732009000	Zn binding site [ion binding]; other site
755732009001	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009002	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
755732009003	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
755732009004	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
755732009005	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
755732009006	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
755732009007	CysD dimerization site [polypeptide binding]; other site
755732009008	G1 box; other site
755732009009	putative GEF interaction site [polypeptide binding]; other site
755732009010	GTP/Mg2+ binding site [chemical binding]; other site
755732009011	Switch I region; other site
755732009012	G2 box; other site
755732009013	G3 box; other site
755732009014	Switch II region; other site
755732009015	G4 box; other site
755732009016	G5 box; other site
755732009017	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
755732009018	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
755732009019	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
755732009020	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
755732009021	Active Sites [active]
755732009022	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
755732009023	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
755732009024	Active Sites [active]
755732009025	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
755732009026	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
755732009027	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
755732009028	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
755732009029	active site
755732009030	SAM binding site [chemical binding]; other site
755732009031	homodimer interface [polypeptide binding]; other site
755732009032	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
755732009033	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
755732009034	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
755732009035	HEPN domain; Region: HEPN; cl00824
755732009036	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
755732009037	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
755732009038	active site
755732009039	catalytic tetrad [active]
755732009040	Predicted transcriptional regulator [Transcription]; Region: COG1959
755732009041	Transcriptional regulator; Region: Rrf2; pfam02082
755732009042	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
755732009043	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
755732009044	aspartate aminotransferase; Provisional; Region: PRK07568
755732009045	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
755732009046	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732009047	homodimer interface [polypeptide binding]; other site
755732009048	catalytic residue [active]
755732009049	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
755732009050	Domain of unknown function DUF21; Region: DUF21; pfam01595
755732009051	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
755732009052	Transporter associated domain; Region: CorC_HlyC; smart01091
755732009053	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
755732009054	Histidine kinase; Region: HisKA_2; pfam07568
755732009055	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732009056	ATP binding site [chemical binding]; other site
755732009057	Mg2+ binding site [ion binding]; other site
755732009058	G-X-G motif; other site
755732009059	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732009060	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732009061	active site
755732009062	phosphorylation site [posttranslational modification]
755732009063	intermolecular recognition site; other site
755732009064	dimerization interface [polypeptide binding]; other site
755732009065	LytTr DNA-binding domain; Region: LytTR; smart00850
755732009066	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732009067	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732009068	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
755732009069	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009070	Cadherin tandem repeat domain; Region: Cadherin_repeat; cd11304
755732009071	Ca2+ binding site [ion binding]; other site
755732009072	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732009073	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
755732009074	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
755732009075	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
755732009076	ligand binding site [chemical binding]; other site
755732009077	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
755732009078	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732009079	active site
755732009080	phosphorylation site [posttranslational modification]
755732009081	intermolecular recognition site; other site
755732009082	dimerization interface [polypeptide binding]; other site
755732009083	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732009084	DNA binding residues [nucleotide binding]
755732009085	dimerization interface [polypeptide binding]; other site
755732009086	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
755732009087	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
755732009088	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
755732009089	DNA binding residues [nucleotide binding]
755732009090	Response regulator receiver domain; Region: Response_reg; pfam00072
755732009091	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732009092	active site
755732009093	phosphorylation site [posttranslational modification]
755732009094	intermolecular recognition site; other site
755732009095	dimerization interface [polypeptide binding]; other site
755732009096	cyclase homology domain; Region: CHD; cd07302
755732009097	nucleotidyl binding site; other site
755732009098	metal binding site [ion binding]; metal-binding site
755732009099	dimer interface [polypeptide binding]; other site
755732009100	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
755732009101	Zn2+ binding site [ion binding]; other site
755732009102	Mg2+ binding site [ion binding]; other site
755732009103	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009104	LytB protein; Region: LYTB; cl00507
755732009105	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
755732009106	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
755732009107	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
755732009108	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
755732009109	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
755732009110	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
755732009111	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
755732009112	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732009113	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
755732009114	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
755732009115	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
755732009116	acyl transferase; Provisional; Region: luxD; PRK13604
755732009117	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
755732009118	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
755732009119	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
755732009120	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
755732009121	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
755732009122	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
755732009123	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
755732009124	hydrophobic ligand binding site; other site
755732009125	SnoaL-like domain; Region: SnoaL_2; pfam12680
755732009126	AIPR protein; Region: AIPR; pfam10592
755732009127	Protein of unknown function (DUF3010); Region: DUF3010; pfam11215
755732009128	Catalytic domain of Protein Kinases; Region: PKc; cd00180
755732009129	active site
755732009130	ATP binding site [chemical binding]; other site
755732009131	substrate binding site [chemical binding]; other site
755732009132	activation loop (A-loop); other site
755732009133	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
755732009134	active site
755732009135	Peptidase S46; Region: Peptidase_S46; pfam10459
755732009136	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
755732009137	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
755732009138	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
755732009139	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
755732009140	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
755732009141	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
755732009142	nucleotide binding site [chemical binding]; other site
755732009143	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
755732009144	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
755732009145	Zn2+ binding site [ion binding]; other site
755732009146	Mg2+ binding site [ion binding]; other site
755732009147	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
755732009148	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
755732009149	RimM N-terminal domain; Region: RimM; pfam01782
755732009150	Methyltransferase domain; Region: Methyltransf_31; pfam13847
755732009151	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732009152	S-adenosylmethionine binding site [chemical binding]; other site
755732009153	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
755732009154	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
755732009155	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
755732009156	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
755732009157	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
755732009158	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
755732009159	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
755732009160	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
755732009161	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
755732009162	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
755732009163	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
755732009164	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
755732009165	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732009166	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732009167	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
755732009168	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009169	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
755732009170	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
755732009171	ligand binding site [chemical binding]; other site
755732009172	flexible hinge region; other site
755732009173	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
755732009174	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
755732009175	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
755732009176	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
755732009177	catalytic residue [active]
755732009178	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
755732009179	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
755732009180	S-adenosylmethionine binding site [chemical binding]; other site
755732009181	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
755732009182	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
755732009183	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
755732009184	putative acyl-acceptor binding pocket; other site
755732009185	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; pfam09912
755732009186	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
755732009187	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
755732009188	intersubunit interface [polypeptide binding]; other site
755732009189	cystathionine beta-synthase; Region: cysta_beta; TIGR01137
755732009190	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
755732009191	dimer interface [polypeptide binding]; other site
755732009192	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732009193	catalytic residue [active]
755732009194	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
755732009195	Serine hydrolase (FSH1); Region: FSH1; pfam03959
755732009196	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
755732009197	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
755732009198	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
755732009199	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732009200	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
755732009201	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
755732009202	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
755732009203	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
755732009204	Coenzyme A binding pocket [chemical binding]; other site
755732009205	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
755732009206	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
755732009207	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
755732009208	HlyD family secretion protein; Region: HlyD_3; pfam13437
755732009209	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
755732009210	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
755732009211	putative active site [active]
755732009212	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
755732009213	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732009214	Walker A/P-loop; other site
755732009215	ATP binding site [chemical binding]; other site
755732009216	Q-loop/lid; other site
755732009217	ABC transporter signature motif; other site
755732009218	Walker B; other site
755732009219	D-loop; other site
755732009220	H-loop/switch region; other site
755732009221	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
755732009222	ATP-GRASP peptide maturase, grasp-with-spasm system; Region: GRASP_w_spasm; TIGR04192
755732009223	ATP-grasp domain; Region: ATP-grasp_4; cl17255
755732009224	O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133
755732009225	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
755732009226	homodimer interface [polypeptide binding]; other site
755732009227	substrate-cofactor binding pocket; other site
755732009228	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732009229	catalytic residue [active]
755732009230	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
755732009231	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
755732009232	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
755732009233	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
755732009234	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
755732009235	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
755732009236	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
755732009237	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
755732009238	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
755732009239	hypothetical protein; Validated; Region: PRK02101
755732009240	Tandem repeat subunit of reelin and related proteins; Region: Reelin_subrepeat_like; cl15240
755732009241	FOG: PKD repeat [General function prediction only]; Region: COG3291
755732009242	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
755732009243	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
755732009244	hydroxyglutarate oxidase; Provisional; Region: PRK11728
755732009245	Predicted dehydrogenase [General function prediction only]; Region: COG0579
755732009246	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
755732009247	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
755732009248	active site
755732009249	catalytic site [active]
755732009250	substrate binding site [chemical binding]; other site
755732009251	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
755732009252	GIY-YIG motif/motif A; other site
755732009253	active site
755732009254	catalytic site [active]
755732009255	putative DNA binding site [nucleotide binding]; other site
755732009256	metal binding site [ion binding]; metal-binding site
755732009257	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
755732009258	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
755732009259	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
755732009260	Protein export membrane protein; Region: SecD_SecF; cl14618
755732009261	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
755732009262	This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides; Region: GT1_ecORF704_like; cd03822
755732009263	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
755732009264	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
755732009265	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
755732009266	active site
755732009267	motif I; other site
755732009268	motif II; other site
755732009269	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
755732009270	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
755732009271	Ligand binding site; other site
755732009272	Putative Catalytic site; other site
755732009273	DXD motif; other site
755732009274	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
755732009275	Clp amino terminal domain; Region: Clp_N; pfam02861
755732009276	Clp amino terminal domain; Region: Clp_N; pfam02861
755732009277	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732009278	Walker A motif; other site
755732009279	ATP binding site [chemical binding]; other site
755732009280	Walker B motif; other site
755732009281	arginine finger; other site
755732009282	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
755732009283	Walker A motif; other site
755732009284	ATP binding site [chemical binding]; other site
755732009285	Walker B motif; other site
755732009286	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
755732009287	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
755732009288	putative active site [active]
755732009289	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
755732009290	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
755732009291	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
755732009292	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009293	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
755732009294	active site flap/lid [active]
755732009295	nucleophilic elbow; other site
755732009296	catalytic triad [active]
755732009297	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
755732009298	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732009299	binding surface
755732009300	TPR motif; other site
755732009301	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732009302	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732009303	binding surface
755732009304	TPR motif; other site
755732009305	TPR repeat; Region: TPR_11; pfam13414
755732009306	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
755732009307	binding surface
755732009308	TPR motif; other site
755732009309	Tetratricopeptide repeat; Region: TPR_12; pfam13424
755732009310	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
755732009311	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
755732009312	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
755732009313	N-terminal plug; other site
755732009314	ligand-binding site [chemical binding]; other site
755732009315	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009316	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
755732009317	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009318	Histidine kinase; Region: His_kinase; pfam06580
755732009319	ATP binding site [chemical binding]; other site
755732009320	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
755732009321	Mg2+ binding site [ion binding]; other site
755732009322	G-X-G motif; other site
755732009323	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
755732009324	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732009325	active site
755732009326	phosphorylation site [posttranslational modification]
755732009327	intermolecular recognition site; other site
755732009328	dimerization interface [polypeptide binding]; other site
755732009329	LytTr DNA-binding domain; Region: LytTR; smart00850
755732009330	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
755732009331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
755732009332	Walker A/P-loop; other site
755732009333	ATP binding site [chemical binding]; other site
755732009334	Q-loop/lid; other site
755732009335	ABC transporter signature motif; other site
755732009336	Walker B; other site
755732009337	D-loop; other site
755732009338	H-loop/switch region; other site
755732009339	ABC transporter; Region: ABC_tran_2; pfam12848
755732009340	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
755732009341	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
755732009342	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
755732009343	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
755732009344	Response regulator receiver domain; Region: Response_reg; pfam00072
755732009345	active site
755732009346	phosphorylation site [posttranslational modification]
755732009347	intermolecular recognition site; other site
755732009348	dimerization interface [polypeptide binding]; other site
755732009349	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
755732009350	DNA binding residues [nucleotide binding]
755732009351	dimerization interface [polypeptide binding]; other site
755732009352	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
755732009353	Histidine kinase; Region: HisKA_3; pfam07730
755732009354	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
755732009355	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
755732009356	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
755732009357	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
755732009358	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
755732009359	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
755732009360	Tetramer interface [polypeptide binding]; other site
755732009361	active site
755732009362	FMN-binding site [chemical binding]; other site
755732009363	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
755732009364	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
755732009365	active site
755732009366	substrate binding site [chemical binding]; other site
755732009367	metal binding site [ion binding]; metal-binding site
755732009368	Protein of unknown function (DUF3137); Region: DUF3137; pfam11335
755732009369	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
755732009370	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
755732009371	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
755732009372	ornithine aminotransferase; Region: Orn_aminotrans; TIGR01885
755732009373	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
755732009374	inhibitor-cofactor binding pocket; inhibition site
755732009375	pyridoxal 5'-phosphate binding site [chemical binding]; other site
755732009376	catalytic residue [active]
755732009377	Fatty acid desaturase; Region: FA_desaturase; pfam00487
755732009378	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
755732009379	putative di-iron ligands [ion binding]; other site
755732009380	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1672
755732009381	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
755732009382	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
755732009383	CAP-like domain; other site
755732009384	active site
755732009385	primary dimer interface [polypeptide binding]; other site
755732009386	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
755732009387	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
755732009388	ATP binding site [chemical binding]; other site
755732009389	Mg2+ binding site [ion binding]; other site
755732009390	G-X-G motif; other site
755732009391	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
755732009392	anchoring element; other site
755732009393	dimer interface [polypeptide binding]; other site
755732009394	ATP binding site [chemical binding]; other site
755732009395	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
755732009396	active site
755732009397	putative metal-binding site [ion binding]; other site
755732009398	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
755732009399	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
755732009400	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
755732009401	oligomer interface [polypeptide binding]; other site
755732009402	metal binding site [ion binding]; metal-binding site
755732009403	metal binding site [ion binding]; metal-binding site
755732009404	Cl binding site [ion binding]; other site
755732009405	aspartate ring; other site
755732009406	basic sphincter; other site
755732009407	putative hydrophobic gate; other site
755732009408	periplasmic entrance; other site
755732009409	formimidoylglutamase; Provisional; Region: PRK13775
755732009410	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
755732009411	putative active site [active]
755732009412	putative metal binding site [ion binding]; other site
755732009413	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
755732009414	active site