-- dump date 20140619_094251 -- class Genbank::CDS -- table cds_note -- id note YP_004602267.1 PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA; COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: dap:Dacet_2869 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain YP_004602268.1 PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit; COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); HAMAP: DNA replication and repair protein recF; KEGG: cni:Calni_0004 smc domain protein; SPTR: SMC domain protein YP_004602269.1 PFAM: RecF/RecN/SMC N terminal domain; COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR011557:IPR003594:IPR001241:IPR013506:IPR 006171:IPR002288; KEGG: cni:Calni_0005 DNA gyrase subunit B; PFAM: DNA topoisomerase, type IIA, subunit B, region 2; ATP-binding region, ATPase-like; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal; SMART: DNA topoisomerase, type IIA, subunit B or N-terminal; ATP-binding region, ATPase-like; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase, subunit B YP_004602270.1 PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit; COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR005743:IPR002205:IPR006691; KEGG: cni:Calni_0006 DNA gyrase subunit A; PFAM: DNA topoisomerase, type IIA, subunit A or C-terminal; DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A or C-terminal; SPTR: DNA gyrase subunit A; TIGRFAM: DNA gyrase, subunit A YP_004602271.1 PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit; COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; HAMAP: Tetrahydrofolate dehydrogenase/cyclohydrolase; InterPro IPR000672:IPR020630:IPR020631; KEGG: cni:Calni_0007 5,10-methylenetetrahydrofolate dehydrogenase (nadp+); methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: Bifunctional protein folD YP_004602272.1 PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; COGs: COG0486 GTPase; HAMAP: tRNA modification GTPase TrmE; InterPro IPR004520:IPR005225:IPR018948:IPR002917; KEGG: ddf:DEFDS_0006 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE, N-terminal; GTP-binding protein, HSR1-related; SPTR: tRNA modification GTPase TrmE; TIGRFAM: tRNA modification GTPase TrmE; Small GTP-binding protein YP_004602273.1 PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein domain; COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; HAMAP: Glucose-inhibited division protein A; InterPro IPR004416:IPR002218; KEGG: ddf:DEFDS_0007 glucose inhibited division protein A; PFAM: Glucose-inhibited division protein A-related; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; TIGRFAM: Glucose-inhibited division protein A YP_004602274.1 PFAM: Glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A; COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; HAMAP: rRNA small subunit methyltransferase G; InterPro IPR003682; KEGG: ddf:DEFDS_0008 glucose inhibited division protein B; PFAM: rRNA small subunit methyltransferase G; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: rRNA small subunit methyltransferase G YP_004602275.1 PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; KEGG: ddf:DEFDS_0009 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602276.1 COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR001450; KEGG: ddf:DEFDS_0264 4Fe-4S ferredoxin; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin YP_004602277.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: ddf:DEFDS_0263 nitroreductase family protein; PFAM: Nitroreductase-like; SPTR: Nitroreductase family protein YP_004602278.1 PFAM: Nitroreductase family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: ddf:DEFDS_2106 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR, C-terminal; Transcriptional regulator IclR, N-terminal; SMART: Transcriptional regulator IclR, N-terminal; SPTR: Transcriptional regulator, IclR family YP_004602279.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: cni:Calni_0449 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily protein YP_004602280.1 PFAM: Thioesterase superfamily; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR001478:IPR008915; KEGG: cni:Calni_1998 site-2 protease; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Site-2 protease; TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase YP_004602281.1 PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP; COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; HAMAP: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR003821:IPR013512:IPR013644; KEGG: cni:Calni_1999 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal; 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004602282.1 PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: ddf:DEFDS_0122 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase YP_004602283.1 PFAM: Cytidylyltransferase family; COGs: COG0020 Undecaprenyl pyrophosphate synthase; HAMAP: Undecaprenyl pyrophosphate synthase; InterPro IPR001441; KEGG: ddf:DEFDS_0121 undecaprenyl pyrophosphate synthetase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Undecaprenyl pyrophosphate synthetase; TIGRFAM:Di-trans-poly-cis-decaprenylcistransferase- like YP_004602284.1 PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; COGs: COG0233 Ribosome recycling factor; HAMAP: Ribosome recycling factor, bacterial-like; InterPro IPR002661:IPR015998; KEGG: ddf:DEFDS_0120 ribosome recycling factor Frr; PFAM: Ribosome recycling factor; SPTR: Ribosome-recycling factor; TIGRFAM: Ribosome recycling factor YP_004602285.1 PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor; COGs: COG0528 Uridylate kinase; InterPro IPR015963:IPR001048; KEGG: cni:Calni_2003 uridylate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Uridylate kinase; TIGRFAM: Uridylate kinase, bacteria YP_004602286.1 PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase; KEGG: ddf:DEFDS_0118 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602287.1 COGs: COG0681 Signal peptidase I; InterPro IPR000223:IPR019759; KEGG: ddf:DEFDS_0117 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I YP_004602288.1 PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein lepA; InterProIPR005225:IPR006297:IPR000795:IPR004161:IPR 000640:IPR013842; KEGG: ddf:DEFDS_0116 GTP-binding protein LepA; PFAM: GTP-binding protein LepA, C-terminal; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor 4; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein YP_004602289.1 PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: ddf:DEFDS_0115 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: Nucleotide sugar dehydrogenase YP_004602290.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602291.1 COGs: COG1484 DNA replication protein; InterPro IPR003593:IPR002611; KEGG: toc:Toce_0299 IstB domain protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core; SPTR: IstB domain protein ATP-binding protein YP_004602292.1 PFAM: IstB-like ATP binding protein; COGs: COG4584 Transposase and inactivated derivatives; KEGG: toc:Toce_1959 integrase catalytic region; SPTR: Integrase catalytic region YP_004602293.1 PFAM: Integrase core domain YP_004602294.1 InterPro IPR001450; KEGG: ddf:DEFDS_0633 2-oxoacid oxidoreductase subunit delta; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 2-oxoacid oxidoreductase, delta subunit YP_004602295.1 PFAM: 4Fe-4S binding domain; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: ddf:DEFDS_0634 2-oxoacid oxidoreductase subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); SPTR: 2-oxoacid oxidoreductase, alpha subunit YP_004602296.1 PFAM: domain; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: ddf:DEFDS_0635 2-oxoacid oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoacid oxidoreductase, beta subunit YP_004602297.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: ddf:DEFDS_0636 2-oxoacid oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: 2-oxoacid oxidoreductase, gamma subunit YP_004602298.1 PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: fpl:Ferp_1517 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase YP_004602299.1 PFAM: Acylphosphatase; COGs: COG0422 Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: ddf:DEFDS_1615 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: Thiamine biosynthesis protein ThiC YP_004602300.1 PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC; COGs: COG0352 Thiamine monophosphate synthase; HAMAP: Thiamine-phosphate pyrophosphorylase; InterPro IPR003733; KEGG: cni:Calni_0756 thiamine-phosphate diphosphorylase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: Thiamine monophosphate synthase YP_004602301.1 PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase; COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283:IPR000728:IPR010918; KEGG: dap:Dacet_2993 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; PRIAM: Thiamine-phosphate kinase; SPTR: Thiamine-monophosphate kinase; TIGRFAM: Thiamine-monophosphate kinase YP_004602302.1 PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase; COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: tye:THEYE_A1664 metal dependent hydrolase; SPTR: Metal dependent hydrolase YP_004602304.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR001498; KEGG: ddf:DEFDS_0500 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: Putative uncharacterized protein YP_004602305.1 PFAM: Uncharacterized protein family UPF0029; TIGRFAM: uncharacterized protein, YigZ family; KEGG: cni:Calni_0020 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602306.1 KEGG: dap:Dacet_0979 glycoside hydrolase family 13 domain protein YP_004602307.1 InterPro IPR004193; KEGG: dap:Dacet_0980 hypothetical protein; PFAM: Glycoside hydrolase, family 13, N-terminal; SPTR: Conserved hypothetical 5-AMP-activated protein kinase, beta-1 subunit (AMPK beta-1 chain) (AMPKb) YP_004602308.1 PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284:IPR007627:IPR013249; KEGG: cni:Calni_0017 RNA polymerase, sigma-24 subunit, ecf subfamily; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70 YP_004602309.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; KEGG: gme:Gmet_3452 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602310.1 PFAM: Pollen proteins Ole e I like; InterPro IPR000620; KEGG: hel:HELO_1870 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein YP_004602311.1 PFAM: EamA-like transporter family; KEGG: pfa:PF11_0207 conserved Plasmodium protein YP_004602312.1 manually curated; similar to conserved Plasmodium protein YP_004602313.1 PFAM: ATP synthase subunit C; KEGG: gur:Gura_0420 H+-transporting two-sector ATPase, E subunit; SPTR: V-type ATP synthase subunit E YP_004602314.1 PFAM: ATP synthase (E/31 kDa) subunit YP_004602315.1 InterPro IPR008218; KEGG: vacuolar H+transporting two-sector ATPase subunit F; PFAM: ATPase, V1/A1 complex, subunit F; SPTR: Vacuolar H+transporting two-sector ATPase F subunit YP_004602316.1 PFAM: ATP synthase (F/14-kDa) subunit; COGs: COG1155 H+-ATPase subunit A; InterPro IPR004100:IPR000194; KEGG: sodium-transporting two-sector ATPase; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; PRIAM: Sodium-transporting two-sector ATPase; SPTR: H+transporting two-sector ATPase alpha/beta subunit central region YP_004602317.1 PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; COGs: COG1156 H+-ATPase subunit B; InterPro IPR000194; KEGG: gur:Gura_0424 V-type ATP synthase subunit B; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; SPTR: V-type ATP synthase beta chain YP_004602318.1 PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; COGs: COG1394 H+-ATPase subunit D; InterPro IPR002699; KEGG: V-type ATPase subunit D; PFAM: ATPase, V1/A1 complex, subunit D; SPTR: V-type ATPase, D subunit; TIGRFAM: ATPase, V1/A1 complex, subunit D YP_004602319.1 PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dap:Dacet_2033 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1 YP_004602320.1 PFAM: Glycosyl transferases group 1; Domain of unknown function (DUF3524); COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: caa:Caka_1649 RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein, NodT family; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT YP_004602321.1 PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: dat:HRM2_02380 putative membrane-fusion protein; PFAM: Secretion protein HlyD; SPTR: Putative membrane-fusion protein; TIGRFAM: Secretion protein HlyD YP_004602322.1 PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: ddf:DEFDS_1907 RND efflux system multidrug efflux transporter; PFAM: Acriflavin resistance protein; SPTR: RND efflux system, multidrug efflux transporter YP_004602323.1 PFAM: AcrB/AcrD/AcrF family; KEGG: tjr:TherJR_2273 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602324.1 InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004602325.1 PFAM: Transposase domain (DUF772); manually curated YP_004602326.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; KEGG: dde:Dde_3307 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602327.1 PFAM: Trypsin; COGs: COG1391 Glutamine synthetase adenylyltransferase; InterPro IPR005190:IPR013546; KEGG: ddf:DEFDS_2134 glutamate-ammonia ligase adenylyltransferase; PFAM: Glutamate-ammonia ligase adenylyltransferase; PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase; PRIAM: [Glutamate--ammonia-ligase] adenylyltransferase; SPTR: Glutamate-ammonia ligase adenylyltransferase YP_004602328.1 PFAM: GlnD PII-uridylyltransferase; Glutamate-ammonia ligase adenylyltransferase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: cni:Calni_1866 thiamine monophosphate synthase; PFAM: Thiamine monophosphate synthase; SPTR: Putative uncharacterized protein YP_004602329.1 PFAM: Thiamine monophosphate synthase/TENI; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: dap:Dacet_0096 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR, C-terminal; Transcriptional regulator IclR, N-terminal; SMART: Transcriptional regulator IclR, N-terminal; SPTR: Transcriptional regulator, IclR family YP_004602330.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225:IPR003373:IPR002917:IPR011619:IPR 011642:IPR011640; KEGG: cni:Calni_1021 ferrous iron transport protein B; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B, N-terminal; Nucleoside recognition; Ferrous iron transport protein B, C-terminal; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein YP_004602331.1 PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain; InterPro IPR007167; KEGG: cni:Calni_1020 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SPTR: FeoA family protein YP_004602332.1 PFAM: FeoA domain; COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: cni:Calni_1019 positive regulator of sigma e, rsec/mucc; PFAM: Positive regulator of sigma(E), RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC YP_004602333.1 PFAM: Positive regulator of sigma(E), RseC/MucC; COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; InterPro IPR001636; KEGG: ddf:DEFDS_1861 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase YP_004602334.1 PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR013027:IPR004099; KEGG: cni:Calni_0602 fad-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_004602335.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR006467:IPR006638:IPR013848:IPR 007197; KEGG: cni:Calni_0603 MiaB-like tRNA modifying enzyme; PFAM: Radical SAM; Methylthiotransferase, N-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: MiaB-like tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; Methylthiotransferase YP_004602336.1 PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family; COGs: COG2844 UTP:GlnB (protein PII) uridylyltransferase; HAMAP: Protein-PII uridylyltransferase; InterProIPR010043:IPR002934:IPR013546:IPR006674:IPR 002912; KEGG: ddf:DEFDS_1857 protein-P-II uridylyltransferase; PFAM: PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase; Nucleotidyltransferase; Metal-dependent phosphohydrolase, HD region, subdomain; Amino acid-binding ACT; PRIAM: [Protein-PII] uridylyltransferase; SPTR: [Protein-PII] uridylyltransferase; TIGRFAM: Protein-PII uridylyltransferase YP_004602337.1 PFAM: GlnD PII-uridylyltransferase; HD domain; ACT domain; Nucleotidyltransferase domain; TIGRFAM: [Protein-PII] uridylyltransferase; COGs: COG0341 Preprotein translocase subunit SecF; InterPro IPR005665:IPR003335; KEGG: ddf:DEFDS_0095 preprotein translocase subunit F; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Preprotein translocase subunit F; TIGRFAM: SecF protein; SecD/SecF/SecDF export membrane protein YP_004602338.1 PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR005791:IPR003335; KEGG: ddf:DEFDS_0094 preprotein translocase subunit D; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Preprotein translocase subunit D; TIGRFAM: SecD export membrane protein; SecD/SecF/SecDF export membrane protein YP_004602339.1 PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: ddf:DEFDS_0093 preprotein translocase subunit YajC; PFAM: YajC; SPTR: Preprotein translocase subunit YajC; TIGRFAM: YajC YP_004602340.1 PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; HAMAP: Queuine tRNA-ribosyltransferase; InterPro IPR004803:IPR002616; KEGG: ddf:DEFDS_0092 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: Queuine tRNA-ribosyltransferase; Queuine/other tRNA-ribosyltransferase YP_004602341.1 PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming; COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); HAMAP: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; InterPro IPR003699; KEGG: dap:Dacet_2454 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; TIGRFAM: Queuosine biosynthesis protein; manually curated YP_004602342.1 PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; COGs: COG0498 Threonine synthase; InterPro IPR004450:IPR001926; KEGG: dap:Dacet_2455 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase YP_004602343.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase; COGs: COG0105 Nucleoside diphosphate kinase; HAMAP: Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: cni:Calni_1237 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase, core; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase, core; SPTR: Nucleoside diphosphate kinase YP_004602344.1 PFAM: Nucleoside diphosphate kinase; InterPro IPR013096; KEGG: ddf:DEFDS_2012 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein YP_004602345.1 PFAM: Cupin domain; InterPro IPR006153; KEGG: dap:Dacet_2458 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; SPTR: Sodium/hydrogen exchanger YP_004602346.1 PFAM: Sodium/hydrogen exchanger family; KEGG: dap:Dacet_2459 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602347.1 KEGG: cni:Calni_0747 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602348.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; HAMAP: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; InterPro IPR003526; KEGG: cni:Calni_0748 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core YP_004602349.1 PFAM: YgbB family; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; COGs: COG0751 Glycyl-tRNA synthetase beta subunit; HAMAP: Glycyl-tRNA synthetase beta subunit; InterPro IPR015944:IPR002311:IPR008909; KEGG: ddf:DEFDS_0236 glycyl-tRNA synthetase subunit beta; PFAM: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal; DALR anticodon binding; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase beta subunit; TIGRFAM: Glycyl-tRNA synthetase, class IIc, beta subunit YP_004602350.1 PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR010121:IPR002192:IPR008279:IPR000121; KEGG: ddf:DEFDS_0235 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase YP_004602351.1 PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase; KEGG: ddf:DEFDS_0088 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602352.1 KEGG: cni:Calni_2056 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602353.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: dap:Dacet_2810 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Histidine kinase YP_004602354.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ddf:DEFDS_0085 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Putative uncharacterized protein YP_004602355.1 PFAM: Response regulator receiver domain; COGs: COG2518 Protein-L-isoaspartate carboxylmethyltransferase; InterPro IPR000682; KEGG: ddf:DEFDS_0260 protein-L-isoaspartate (D-aspartate) O-methyltransferase; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase; PRIAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase; SPTR: Protein-L-isoaspartate O-methyltransferase YP_004602356.1 PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; COGs: COG0548 Acetylglutamate kinase; InterPro IPR004662:IPR001048; KEGG: cni:Calni_0262 N-acetylglutamate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Acetylglutamate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: Acetylglutamate kinase YP_004602357.1 PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase; KEGG: cni:Calni_1417 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602359.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: cni:Calni_0924 UspA domain-containing protein; PFAM: UspA; SPTR: UspA domain-containing protein YP_004602360.1 PFAM: Universal stress protein family; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: cni:Calni_0924 UspA domain-containing protein; PFAM: UspA; SPTR: UspA domain-containing protein YP_004602361.1 PFAM: Universal stress protein family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cni:Calni_0923 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein YP_004602362.1 PFAM: Response regulator receiver domain; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: ddf:DEFDS_0065 deoxyribonuclease TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Deoxyribonuclease, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote YP_004602363.1 PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; COGs: COG0143 Methionyl-tRNA synthetase; HAMAP: Methionyl-tRNA synthetase; InterPro IPR002304:IPR004495:IPR015413:IPR002547; KEGG: cni:Calni_0921 methionyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); tRNA-binding region; PRIAM: Methionine--tRNA ligase; SPTR: Methionyl-tRNA synthetase; TIGRFAM: Methionyl-tRNA synthetase, class Ia; Methionyl-tRNA synthetase, class Ia, beta subunit, C-terminal YP_004602364.1 PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: cni:Calni_0920 PSP1 domain protein; PFAM: PSP1, C-terminal; SPTR: PSP1 domain protein YP_004602365.1 PFAM: PSP1 C-terminal conserved region; COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: dap:Dacet_2365 DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase YP_004602366.1 TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG0125 Thymidylate kinase; HAMAP: Thymidylate kinase; InterPro IPR018094:IPR000062; KEGG: ddf:DEFDS_0069 dTMP kinase; PFAM: Thymidylate kinase-like; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: Thymidylate kinase YP_004602367.1 PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: Molybdopterin binding; Molybdenum cofactor sulfurase, C-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: Molybdenum cofactor synthesis YP_004602368.1 PFAM: Probable molybdopterin binding domain; MOSC domain; TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR004607:IPR002376; KEGG: ddf:DEFDS_0168 phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase, N-terminal; PRIAM: Phosphoribosylglycinamide formyltransferase; SPTR: Phosphoribosylglycinamide formyltransferase; TIGRFAM: Phosphoribosylglycinamide formyltransferase YP_004602369.1 PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733:IPR000728:IPR010918; KEGG: ddf:DEFDS_0167 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase YP_004602370.1 PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase; InterPro IPR001789; KEGG: ddf:DEFDS_0166 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Putative uncharacterized protein YP_004602371.1 PFAM: Response regulator receiver domain; KEGG: cni:Calni_0657 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602372.1 PFAM: CheW-like domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR001789:IPR 004105; KEGG: ddf:DEFDS_0164 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup, homodimeric; CheW-like protein; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SPTR: Putative uncharacterized protein YP_004602373.1 PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: cni:Calni_0655 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer YP_004602374.1 PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: psm:PSM_A2230 purine-binding chemotaxis protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Purine-binding chemotaxis protein YP_004602375.1 PFAM: CheW-like domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ddf:DEFDS_0161 twitching motility two-component system response regulator PilH; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Twitching motility two-component system response regulator PilH YP_004602376.1 PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cni:Calni_0652 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein YP_004602377.1 PFAM: Response regulator receiver domain; COGs: COG0669 Phosphopantetheine adenylyltransferase; HAMAP: Coenzyme A biosynthesis protein; InterPro IPR004821:IPR001980:IPR004820; KEGG: cni:Calni_0650 phosphopantetheine adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: Coenzyme A biosynthesis protein; Cytidyltransferase-related YP_004602378.1 PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR016065; KEGG: ddf:DEFDS_0157 DNA methylase; PFAM: Protein of unknown function methylase putative; SPTR: DNA methylase; TIGRFAM: Conserved hypothetical protein CHP00095; manually curated YP_004602379.1 PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; COGs: COG1243 Histone acetyltransferase; InterPro IPR006638:IPR007197; KEGG: dap:Dacet_3015 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein YP_004602380.1 PFAM: Radical SAM superfamily; COGs: COG0571 dsRNA-specific ribonuclease; HAMAP: Ribonuclease III, bacterial; InterPro IPR011907:IPR000999:IPR001159; KEGG: cni:Calni_1228 RNase III; PFAM: Ribonuclease III; Double-stranded RNA binding; PRIAM: Ribonuclease III; SMART: Ribonuclease III; Double-stranded RNA binding; SPTR: Ribonuclease 3; TIGRFAM: Ribonuclease III, bacterial YP_004602381.1 PFAM: Double-stranded RNA binding motif; RNase3 domain; TIGRFAM: ribonuclease III, bacterial; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR017568:IPR014030:IPR014031; KEGG: ddf:DEFDS_0154 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 2; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2 YP_004602382.1 PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II; HAMAP: Acyl carrier protein (ACP); InterPro IPR003231:IPR006163; KEGG: ddf:DEFDS_0153 acyl carrier protein ACP; PFAM: Phosphopantetheine-binding; SPTR: Acyl carrier protein; TIGRFAM: Acyl carrier protein (ACP) YP_004602383.1 PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR011284:IPR002198; KEGG: cni:Calni_1225 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-(Acyl-carrier-protein) reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_004602384.1 PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043; KEGG: cni:Calni_1224 (acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; SPTR: (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase YP_004602385.1 PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); HAMAP: Beta-ketoacyl-acyl carrier protein synthase III (FabH); InterPro IPR004655:IPR013751:IPR013747; KEGG: cni:Calni_1223 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 3; TIGRFAM: Beta-ketoacyl-acyl carrier protein synthase III (FabH) YP_004602386.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0416 Fatty acid/phospholipid biosynthesis enzyme; HAMAP: Phospholipid biosynthesis protein, PlsX like; InterPro IPR012281:IPR003664; KEGG: ddf:DEFDS_0149 fatty acid/phospholipid synthesis protein PlsX; PFAM: Fatty acid synthesis plsX protein; SPTR: Phosphate acyltransferase; TIGRFAM: Phospholipid biosynthesis protein, PlsX like YP_004602387.1 PFAM: Fatty acid synthesis protein; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX; COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: ddf:DEFDS_0148 50S ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p YP_004602388.1 PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: cni:Calni_1220 hypothetical protein; PFAM: Protein of unknown function DUF177; SPTR: Putative uncharacterized protein YP_004602389.1 PFAM: Uncharacterized ACR, COG1399; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ddf:DEFDS_0619 aspartate transaminase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate transaminase YP_004602390.1 PFAM: Aminotransferase class I and II; COGs: COG4276 conserved hypothetical protein; KEGG: dap:Dacet_2029 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602391.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); HAMAP: Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; InterPro IPR005882:IPR005835:IPR001451; KEGG: dap:Dacet_2836 UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; TIGRFAM: Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004602392.1 PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; HAMAP: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; InterPro IPR005855:IPR000583:IPR001347; KEGG: cni:Calni_0410 glutamine--fructose-6-phosphate transaminase; PFAM: Glutamine amidotransferase, class-II; Sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine--fructose-6-phosphate transaminase; TIGRFAM: Glucosamine-fructose-6-phosphate aminotransferase, isomerising YP_004602393.1 PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing); COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644:IPR001807; KEGG: ddf:DEFDS_1948 chloride channel protein, CIC family; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SPTR: Chloride channel protein, CIC family YP_004602394.1 PFAM: CBS domain; Voltage gated chloride channel; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: dap:Dacet_2392 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase YP_004602395.1 PFAM: UvrD/REP helicase; COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; HAMAP: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; InterPro IPR003837; KEGG: ddf:DEFDS_1950 aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase, C subunit; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; TIGRFAM: Glu-tRNAGln amidotransferase, C subunit YP_004602396.1 PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; HAMAP: Glutamyl-tRNA(Gln) amidotransferase A subunit; InterPro IPR004412:IPR000120; KEGG: ddf:DEFDS_1951 aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit A; PFAM: Amidase; PRIAM: Amidase; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase A subunit YP_004602397.1 PFAM: Amidase; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; InterPro IPR009288; KEGG: cni:Calni_1048 hypothetical protein; PFAM: AIG2-like; SPTR: Putative uncharacterized protein YP_004602398.1 PFAM: AIG2-like family; COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); HAMAP: Glutamyl-tRNA(Gln) amidotransferase, B subunit; InterPro IPR004413:IPR006075:IPR006107:IPR018027; KEGG: ddf:DEFDS_1934 aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit B; PFAM: Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, N-terminal; Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, central region; Asn/Gln amidotransferase; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase, B subunit YP_004602399.1 PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; InterPro IPR017515:IPR004360; KEGG: dap:Dacet_2428 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Methylmalonyl-CoA epimerase; TIGRFAM: Methylmalonyl-CoA epimerase YP_004602400.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: ddf:DEFDS_1937 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein YP_004602401.1 PFAM: Rhodanese-like domain; COGs: COG3221 ABC-type phosphate/phosphonate transport system periplasmic component; KEGG: ddf:DEFDS_1456 phosphate/phosphonate ABC transporter substrate-binding protein; SPTR: Phosphate/phosphonate ABC transporter, substrate-binding protein YP_004602402.1 PFAM: NMT1/THI5 like; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004602403.1 PFAM: Transposase DDE domain; manually curated YP_004602404.1 manually curated YP_004602405.1 PFAM: Transposase DDE domain; KEGG: aeh:Mlg_0129 transposase, IS4 family protein; SPTR: Transposase, IS4 family YP_004602406.1 KEGG: drt:Dret_0154 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004602407.1 PFAM: Protein of unknown function (DUF1271); COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: nth:Nther_1561 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase YP_004602408.1 PFAM: NADPH-dependent FMN reductase; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602409.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: ddf:DEFDS_1448 RND efflux system multidrug efflux transporter; PFAM: Acriflavin resistance protein; SPTR: RND efflux system, multidrug efflux transporter YP_004602410.1 PFAM: AcrB/AcrD/AcrF family; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: ddf:DEFDS_1449 RND efflux system membrane fusion protein; PFAM: Secretion protein HlyD; SPTR: RND efflux system, membrane fusion protein; TIGRFAM: Secretion protein HlyD YP_004602411.1 PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ddf:DEFDS_1450 RND efflux system outer membrane lipoprotein; PFAM: Outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein YP_004602412.1 PFAM: Outer membrane efflux protein; InterPro IPR001647; KEGG: tcx:Tcr_1884 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family YP_004602413.1 PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR013096; KEGG: hor:Hore_08490 cupin 2 conserved barrel domain protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein YP_004602414.1 PFAM: Cupin domain; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: ddf:DEFDS_1073 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: NADH dehydrogenase (ubiquinone); SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_004602415.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004602416.1 PFAM: Transposase DDE domain; InterPro IPR000620; KEGG: dak:DaAHT2_2429 protein of unknown function DUF6 transmembrane; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein YP_004602417.1 PFAM: EamA-like transporter family; KEGG: dtu:Dtur_1639 nitroreductase; SPTR: Nitroreductase YP_004602418.1 PFAM: Nitroreductase family; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: msv:Mesil_3173 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602419.1 PFAM: Transposase DDE domain; COGs: COG3189 conserved hypothetical protein; InterPro IPR007438; KEGG: noc:Noc_2090 hypothetical protein; PFAM: Protein of unknown function DUF488; SPTR: Putative uncharacterized protein YP_004602420.1 PFAM: Protein of unknown function, DUF488 YP_004602421.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); HAMAP: Trigger factor; InterPro IPR005215:IPR008881:IPR001179:IPR008880; KEGG: ddf:DEFDS_0192 trigger factor; PFAM: Trigger factor, ribosome-binding, bacterial; Peptidyl-prolyl cis-trans isomerase, FKBP-type; Trigger factor, C-terminal, bacterial; SPTR: Trigger factor; TIGRFAM: Trigger factor YP_004602422.1 PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor; COGs: COG0740 Protease subunit of ATP-dependent Clp protease; HAMAP: ATP-dependent Clp protease proteolytic subunit; InterPro IPR001907; KEGG: cni:Calni_1041 ATP-dependent clp protease proteolytic subunit ClpP; PFAM: Peptidase S14, ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: Peptidase S14, ClpP YP_004602423.1 PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; COGs: COG1219 ATP-dependent protease Clp ATPase subunit; HAMAP: Clp protease, ATP-binding subunit ClpX; InterProIPR004487:IPR003593:IPR010603:IPR013093:IPR 019489; KEGG: ddf:DEFDS_0194 ATP-dependent Clp protease ATP-binding subunit; PFAM: ATPase associated with various cellular activities, AAA-2; Zinc finger, C4-type; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpX; TIGRFAM: Clp protease, ATP-binding subunit ClpX YP_004602424.1 PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX); COGs: COG0466 ATP-dependent Lon protease; InterProIPR004815:IPR003111:IPR003593:IPR003959:IPR 008269; KEGG: ddf:DEFDS_0195 ATP-dependent Lon protease; PFAM: Peptidase S16, lon C-terminal; Peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: Peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: Peptidase S16, ATP-dependent protease La YP_004602425.1 PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La; HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: ddf:DEFDS_0196 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21 YP_004602426.1 PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: cni:Calni_1837 hypothetical protein; PFAM: Protein of unknown function DUF111; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF111 YP_004602427.1 PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: dau:Daud_0314 appr-1-p processing domain-containing protein; PFAM: Appr-1-p processing; SMART: Appr-1-p processing; SPTR: Appr-1-p processing domain protein YP_004602428.1 PFAM: Macro domain; COGs: COG2113 ABC-type proline/glycine betaine transport systems periplasmic components; InterPro IPR007210; KEGG: dde:Dde_0146 putative glycine betaine/L-proline ABC transporter solute-binding protein; PFAM: ABC-type glycine betaine transport system, substrate-binding region; SPTR: Putative glycine betaine/L-proline ABC transporter, solute-binding protein YP_004602429.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system; TIGRFAM: choline ABC transporter, periplasmic binding protein; COGs: COG0499 S-adenosylhomocysteine hydrolase; HAMAP: Adenosylhomocysteinase; InterPro IPR000043:IPR015878; KEGG: cni:Calni_0569 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase, NAD binding; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: S-adenosyl-L-homocysteine hydrolase YP_004602430.1 PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR013751; KEGG: ddf:DEFDS_1929 thiolase family protein; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Propanoyl-CoA C-acyltransferase; SPTR: Thiolase family protein YP_004602431.1 PFAM: Thiolase, C-terminal domain; manually curated YP_004602432.1 PFAM: Transposase DDE domain; manually curated YP_004602433.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218; KEGG: ddf:DEFDS_0830 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 YP_004602434.1 PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG1151 6Fe-6S prismane cluster-containing protein; HAMAP: Hybrid cluster protein; InterPro IPR010048:IPR004137; KEGG: cni:Calni_0496 hybrid cluster protein; PFAM: Prismane; SPTR: Hydroxylamine reductase; TIGRFAM: Hybrid cluster protein YP_004602435.1 PFAM: Prismane/CO dehydrogenase family; TIGRFAM: hydroxylamine reductase; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: cni:Calni_0497 transcriptional regulator, crp/fnr family; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family YP_004602436.1 PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; KEGG: ddf:DEFDS_0027 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602437.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: tdn:Suden_0117 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein YP_004602438.1 PFAM: Periplasmic binding protein; COGs: COG4139 ABC-type cobalamin transport system permease component; InterPro IPR000522; KEGG: aoe:Clos_0916 transport system permease protein; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein YP_004602439.1 PFAM: FecCD transport family; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: cpr:CPR_0781 iron(III) dicitrate transport permease-like protein YusV; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ferrichrome transport ATP-binding protein FhuC YP_004602440.1 PFAM: ABC transporter; COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: cni:Calni_1879 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor plug YP_004602441.1 PFAM: TonB-dependent Receptor Plug Domain; COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260:IPR003538; KEGG: hpc:HPPC_06595 siderophore-mediated iron transport protein (TonB); PFAM: Gram-negative bacterial tonB protein; SPTR: Siderophore-mediated iron transport protein (TonB); TIGRFAM: TonB, C-terminal YP_004602442.1 PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; COGs: COG0785 Cytochrome c biogenesis protein; InterPro IPR003834; KEGG: ddf:DEFDS_0172 cytochrome c-type biogenesis protein; PFAM: Cytochrome c assembly protein, transmembrane region; SPTR: Cytochrome c-type biogenesis protein YP_004602443.1 PFAM: Cytochrome C biogenesis protein transmembrane region; COGs: COG2332 Cytochrome c-type biogenesis protein CcmE; InterPro IPR004329; KEGG: cni:Calni_1688 CcmE/CycJ protein; PFAM: CcmE/CycJ protein; SPTR: CcmE/CycJ protein YP_004602444.1 PFAM: CcmE; InterPro IPR003660; KEGG: gme:Gmet_0018 metal dependent phosphohydrolase; PFAM: HAMP linker domain; SMART: HAMP linker domain; SPTR: Metal dependent phosphohydrolase YP_004602445.1 PFAM: HAMP domain; Protein of unknown function (DUF3365) YP_004602446.1 COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: cni:Calni_0600 methylated-DNA/protein-cysteinemethyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR:Methylated-DNA/protein-cysteinemethyltransfera se; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding YP_004602447.1 PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: ddf:DEFDS_1996 tRNA/rRNA methyltransferase; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; NusB/RsmB/TIM44; SPTR: tRNA/rRNA methyltransferase YP_004602448.1 PFAM: NOL1/NOP2/sun family; NusB family; COGs: COG0501 Zn-dependent protease with chaperone function; HAMAP: protease htpX; InterPro IPR001915; KEGG: ddf:DEFDS_1995 peptidase M48 family; PFAM: Peptidase M48, Ste24p; SPTR: Protease HtpX homolog YP_004602449.1 PFAM: Peptidase family M48; COGs: COG1852 conserved hypothetical protein; InterPro IPR002829; KEGG: cni:Calni_0072 hypothetical protein; PFAM: Protein of unknown function DUF116; SPTR: Putative uncharacterized protein YP_004602450.1 PFAM: Protein of unknown function DUF116; COGs: COG0223 Methionyl-tRNA formyltransferase; HAMAP: Methionyl-tRNA formyltransferase; InterPro IPR005794:IPR002376:IPR005793; KEGG: ddf:DEFDS_1994 methionyl-tRNA formyltransferase; PFAM: Formyl transferase, C-terminal; Formyl transferase, N-terminal; PRIAM: Methionyl-tRNA formyltransferase; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: Methionyl-tRNA formyltransferase YP_004602451.1 PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ddf:DEFDS_1993 aminotransferase I and II; PFAM: Aminotransferase, class I/II; PRIAM: LL-diaminopimelate aminotransferase; SPTR: Aminotransferase, I and II YP_004602452.1 PFAM: Aminotransferase class I and II; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: ddf:DEFDS_1992 cation efflux protein; PFAM: Cation efflux protein; SPTR: Cation efflux protein; TIGRFAM: Cation efflux protein YP_004602453.1 PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; InterPro IPR018710; KEGG: ddf:DEFDS_1990 hypothetical protein; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Putative uncharacterized protein YP_004602454.1 PFAM: Predicted membrane protein (DUF2232); COGs: COG0238 Ribosomal protein S18; HAMAP: 30S ribosomal protein S18; InterPro IPR001648; KEGG: dap:Dacet_0006 30S ribosomal protein S18; PFAM: Ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: Ribosomal protein S18 YP_004602455.1 PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: ddf:DEFDS_1988 single-strand DNA binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding YP_004602456.1 PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); COGs: COG0360 Ribosomal protein S6; HAMAP: Ribosomal protein S6, bacterial-like; InterPro IPR000529:IPR020814; KEGG: cni:Calni_0515 ribosomal protein S6; PFAM: Ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: Ribosomal protein S6 YP_004602457.1 PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225:IPR002942:IPR006145; KEGG: ddf:DEFDS_1986 ribosomal large subunit pseudouridine synthase D; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD YP_004602458.1 PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); HAMAP: NAD(P)H-quinone oxidoreductase subunit 3; InterPro IPR000440; KEGG: ddf:DEFDS_1985 NADH-quinone oxidoreductase subunit A; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3; SPTR: NADH-quinone oxidoreductase subunit YP_004602459.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; HAMAP: NAD(P)H-quinone oxidoreductase subunit K; InterPro IPR006138:IPR006137; KEGG: cni:Calni_0313 NADH dehydrogenase subunit B; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit B; TIGRFAM: NADH:ubiquinone oxidoreductase, 20kDa subunit YP_004602460.1 PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: cni:Calni_0314 NADH dehydrogenase subunit C; PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; SPTR: NADH-quinone oxidoreductase subunit C YP_004602461.1 PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; InterPro IPR010219:IPR001135; KEGG: ddf:DEFDS_1982 NADH-quinone oxidoreductase subunit D; PFAM: NADH-quinone oxidoreductase, subunit D; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, D subunit; TIGRFAM: NADH dehydrogenase I, D subunit YP_004602462.1 PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; TIGRFAM: NADH dehydrogenase I, D subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: cni:Calni_0316 NADH dehydrogenase subunit E; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase subunit E YP_004602463.1 PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575:IPR001450; KEGG: ddf:DEFDS_1980 NADH-quinone oxidoreductase subunit F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, F subunit YP_004602464.1 PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR006963:IPR006656:IPR 006657; KEGG: ddf:DEFDS_1979 NADH-quinone oxidoreductase subunit G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, G subunit YP_004602465.1 PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: NADH-quinone oxidoreductase, chain G; COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); HAMAP: NAD(P)H-quinone oxidoreductase subunit 1; InterPro IPR001694; KEGG: ddf:DEFDS_1978 NADH-quinone oxidoreductase subunit H; PFAM: NADH:ubiquinone oxidoreductase, subunit 1; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit H YP_004602466.1 PFAM: NADH dehydrogenase; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); HAMAP: NADH-quinone oxidoreductase, chain I; InterPro IPR010226:IPR001450; KEGG: ddf:DEFDS_1977 NADH-quinone oxidoreductase subunit I; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: NADH dehydrogenase; SPTR: NADH-quinone oxidoreductase subunit I; TIGRFAM: NADH-quinone oxidoreductase, chain I YP_004602467.1 PFAM: 4Fe-4S binding domain; TIGRFAM: NADH-quinone oxidoreductase, chain I; COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: cni:Calni_0322 NADH dehydrogenase subunit J; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6; SPTR: NADH dehydrogenase subunit J YP_004602468.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); HAMAP: NAD(P)H-quinone oxidoreductase subunit 4L; InterPro IPR001133; KEGG: ddf:DEFDS_1975 NADH-quinone oxidoreductase subunit K; PFAM: NADH:ubiquinone/quinone oxidoreductase, chain 4L; SPTR: NADH-quinone oxidoreductase subunit K YP_004602469.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003945:IPR001516:IPR001750; KEGG: ddf:DEFDS_1974 NADH-quinone oxidoreductase subunit L; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, L subunit; TIGRFAM: NADH-plastoquinone oxidoreductase, chain 5 YP_004602470.1 PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 C-terminus; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR010227:IPR001750; KEGG: ddf:DEFDS_1973 NADH-quinone oxidoreductase subunit M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, M subunit; TIGRFAM: NADH-quinone oxidoreductase, chain M YP_004602471.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); HAMAP: NAD(P)H-quinone oxidoreductase subunit 2; InterPro IPR010096:IPR001750; KEGG: cni:Calni_0326 NADH dehydrogenase subunit N; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit N; TIGRFAM: NADH-quinone oxidoreductase, chain N YP_004602472.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; InterPro IPR003251; KEGG: cni:Calni_0327 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin YP_004602473.1 PFAM: Rubrerythrin; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; InterPro IPR011128:IPR006109; KEGG: cni:Calni_0959 glycerol 3-phosphate dehydrogenase (nad(p)+); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+] YP_004602474.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR006375:IPR005835:IPR001538; KEGG: tcx:Tcr_1678 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_004602475.1 PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR004772:IPR003445; KEGG: dap:Dacet_2985 potassium uptake protein, TrkH family; PFAM: Cation transporter; SPTR: Potassium uptake protein, TrkH family; TIGRFAM: Potassium uptake protein TrkH YP_004602476.1 PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: dap:Dacet_2986 TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: TrkA-N domain protein YP_004602477.1 PFAM: TrkA-N domain; TrkA-C domain; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: pca:Pcar_0560 hypothetical protein; PFAM: Cation/H+ exchanger; SPTR: Sodium/hydrogen exchanger YP_004602478.1 PFAM: Sodium/hydrogen exchanger family; COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR004114:IPR000241; KEGG: dat:HRM2_18410 putative RNA methylase family protein; PFAM: Putative RNA methylase; THUMP; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: Putative uncharacterized protein YP_004602479.1 PFAM: Putative RNA methylase family UPF0020; THUMP domain; COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR002059; KEGG: ddf:DEFDS_1633 cold shock protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Cold shock protein YP_004602480.1 PFAM: 'Cold-shock' DNA-binding domain; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: cte:CT0090 glycosy hydrolase family protein; PFAM: Glycoside hydrolase, family 3, N-terminal; SPTR: Glycosyl hydrolase, family 3 YP_004602481.1 PFAM: Glycosyl hydrolase family 3 N terminal domain; COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: sfu:Sfum_4019 putative ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; TIGRFAM: ATP-binding cassette protein, ChvD family YP_004602482.1 PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family; KEGG: ddf:DEFDS_1656 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602483.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225:IPR006298:IPR000795:IPR004161:IPR 000640; KEGG: cni:Calni_0168 gtp-binding protein TypA; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein YP_004602484.1 PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain; COGs: COG3671 membrane protein; KEGG: tbd:Tbd_1218 transmembrane protein; SPTR: Probable transmembrane protein YP_004602485.1 KEGG: ddf:DEFDS_1670 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated YP_004602486.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003018:IPR001932:IPR001734:IPR010822; KEGG: ddf:DEFDS_1669 serine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; GAF; Sodium/solute symporter; SMART: Protein phosphatase 2C-related; GAF; SPTR: Serine phosphatase YP_004602487.1 PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); InterPro IPR012861; KEGG: phe:Phep_0601 protein of unknown function DUF1634; PFAM: Protein of unknown function DUF1634 YP_004602488.1 PFAM: Protein of unknown function (DUF1634); COGs: COG0730 permease; InterPro IPR002781; KEGG: ddf:DEFDS_1353 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein YP_004602489.1 PFAM: Sulfite exporter TauE/SafE; KEGG: cni:Calni_1694 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602490.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544; KEGG: cni:Calni_0961 branched chain amino acid aminotransferase apoenzyme; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched chain amino acid aminotransferase apoenzyme; TIGRFAM: Branched-chain amino acid aminotransferase II YP_004602491.1 PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II; COGs: COG0068 Hydrogenase maturation factor; InterPro IPR004421:IPR001792:IPR011125:IPR006070; KEGG: ddf:DEFDS_1539 Ni-Fe hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type; SPTR: Ni-Fe hydrogenase maturation protein HypF; TIGRFAM: Hydrogenase maturation factor, HypF-type YP_004602492.1 PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR011023:IPR001678; KEGG: cni:Calni_1279 fmu (sun) domain protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: Fmu (Sun) domain protein; TIGRFAM: Nop2p YP_004602493.1 PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006675:IPR003607:IPR006674; KEGG: ddf:DEFDS_1810 HAD-superfamily hydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: HAD-superfamily hydrolase; TIGRFAM: HDIG YP_004602494.1 PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG0682 Prolipoprotein diacylglyceryltransferase; HAMAP: Prolipoprotein diacylglyceryl transferase; InterPro IPR001640; KEGG: ddf:DEFDS_1811 prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: Prolipoprotein diacylglyceryl transferase YP_004602495.1 PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; InterPro IPR000620; KEGG: cni:Calni_0245 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein YP_004602496.1 PFAM: EamA-like transporter family; InterPro IPR000620; KEGG: dap:Dacet_1633 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein YP_004602497.1 PFAM: EamA-like transporter family YP_004602498.1 COGs: COG0280 Phosphotransacetylase; InterPro IPR004614:IPR002505; KEGG: cni:Calni_0766 phosphotransacetylase; PFAM: Phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase YP_004602499.1 PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0282 Acetate kinase; HAMAP: Acetate kinase; InterPro IPR004372:IPR000890; KEGG: cni:Calni_0765 acetate kinase; PFAM: Acetate/butyrate kinase; PRIAM: Acetate kinase; SPTR: Acetate kinase; TIGRFAM: Acetate kinase YP_004602500.1 PFAM: Acetokinase family; TIGRFAM: acetate kinase; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR010066:IPR003593:IPR003439:IPR013563; KEGG: dap:Dacet_2504 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal YP_004602501.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR010066:IPR003593:IPR003439:IPR013563; KEGG: dal:Dalk_1531 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal YP_004602502.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dap:Dacet_2506 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004602503.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dap:Dacet_2507 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004602504.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: drt:Dret_1361 extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Extracellular solute-binding protein family 5 YP_004602505.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817:IPR005110:IPR001453:IPR005111; KEGG: ddf:DEFDS_1594 molybdopterin biosynthesis protein MoeA; PFAM: MoeA, N-terminal region, domain I/II; Molybdopterin binding; MoeA, C-terminal, domain IV; SPTR: Molybdopterin biosynthesis protein MoeA; TIGRFAM: Molybdenum cofactor synthesis YP_004602506.1 PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: ddf:DEFDS_1595 ribosomal large subunit pseudouridine synthase A; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Ribosomal large subunit pseudouridine synthase A YP_004602507.1 PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; KEGG: dap:Dacet_0352 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated YP_004602508.1 PFAM: Class III cytochrome C family; COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR004559:IPR006638:IPR007197:IPR010723; KEGG: ddf:DEFDS_2032 oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM; HemN, C-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Putative oxygen-independent coproporphyrinogen III oxidase YP_004602509.1 PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: ddf:DEFDS_0328 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004602510.1 PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: lipid A export permease/ATP-binding protein MsbA; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ddf:DEFDS_0329 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase YP_004602511.1 PFAM: Glycosyl transferases group 1; KEGG: fph:Fphi_1263 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602512.1 PFAM: RmlD substrate binding domain; InterPro IPR001173; KEGG: sus:Acid_5170 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, family 2 YP_004602513.1 PFAM: Glycosyl transferase family 2; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005907:IPR005835; KEGG: cpb:Cphamn1_1914 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate thymidylyltransferase; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, long form YP_004602514.1 PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form; manually curated YP_004602515.1 PFAM: Methyltransferase domain; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ddf:DEFDS_0336 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase YP_004602516.1 PFAM: Glycosyl transferases group 1; InterPro IPR007016; KEGG: dvm:DvMF_3018 O-antigen polymerase; PFAM: O-antigen ligase-related; SPTR: O-antigen polymerase YP_004602517.1 PFAM: O-Antigen ligase; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ddf:DEFDS_0337 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase YP_004602518.1 PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dap:Dacet_1893 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1 YP_004602519.1 PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ddf:DEFDS_0338 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase YP_004602520.1 PFAM: Glycosyl transferases group 1; manually curated YP_004602521.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: ddf:DEFDS_0333 ADP-heptose:LPS heptosyltransferase II; PFAM: Glycosyl transferase, family 9; SPTR: ADP-heptose:LPS heptosyltransferase II YP_004602522.1 PFAM: Glycosyltransferase family 9 (heptosyltransferase); KEGG: ddf:DEFDS_0981 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602523.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: ddf:DEFDS_0982 hypothetical protein; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Putative uncharacterized protein YP_004602524.1 PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: pca:Pcar_1271 glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyltransferase YP_004602525.1 PFAM: Glycosyl transferase family 2; COGs: COG3952 membrane protein; InterPro IPR011499; KEGG: ddf:DEFDS_0984 lipid A biosynthesis domain protein; PFAM: Lipid A biosynthesis, N-terminal; SPTR: Lipid A biosynthesis domain protein YP_004602526.1 PFAM: Lipid A Biosynthesis N-terminal domain; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: ddf:DEFDS_0985 hypothetical protein; PFAM: Glycosyl transferase, family 39; SPTR: Putative uncharacterized protein YP_004602527.1 PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: gem:GM21_1846 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase YP_004602528.1 PFAM: Nitroreductase family; InterPro IPR000524; KEGG: ddf:DEFDS_0767 hypothetical protein; PFAM: HTH transcriptional regulator, GntR; SPTR: Putative uncharacterized protein YP_004602529.1 PFAM: Bacterial regulatory proteins, gntR family; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: dsa:Desal_3220 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase, N-terminal; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: 5-oxoprolinase (ATP-hydrolyzing) YP_004602530.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region; COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692; KEGG: ddf:DEFDS_0769 N-methylhydantoinase B; PFAM: Hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase B YP_004602531.1 PFAM: Hydantoinase B/oxoprolinase; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389; KEGG: dat:HRM2_46640 TRAP-type C4-dicarboxylate transport system periplasmic component; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: TRAP-type C4-dicarboxylate transport system periplasmic component YP_004602532.1 PFAM: Bacterial extracellular solute-binding protein, family 7; COGs: COG4665 TRAP-type mannitol/chloroaromatic compound transport system small permease component; InterPro IPR007387; KEGG: ddf:DEFDS_0771 C4-dicarboxylate transporter small subunit; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: C4-dicarboxylate transporter, small subunit YP_004602533.1 PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR004681:IPR010656; KEGG: dat:HRM2_46660 putative TRAP C4-dicarboxylate transport system permease DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: Putative TRAP C4-dicarboxylate transport system permease DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit YP_004602534.1 PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: cni:Calni_0451 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase YP_004602535.1 PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Protein of unknown function (DUF3365); COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cni:Calni_0450 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged helix family YP_004602536.1 PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0348 Polyferredoxin; KEGG: cni:Calni_1875 ferredoxin-type protein, NapH/maun family; SPTR: Ferredoxin-type protein, NapH/MauN family YP_004602537.1 TIGRFAM: ferredoxin-type protein, NapH/MauN family; InterPro IPR001450; KEGG: ddf:DEFDS_1822 periplasmic nitrate reductase NapG; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Periplasmic nitrate reductase NapG YP_004602538.1 TIGRFAM: MauM/NapG family ferredoxin-type protein; KEGG: cni:Calni_1873 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602539.1 PFAM: NapD protein; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR019546:IPR006963:IPR006656:IPR 006657; KEGG: ddf:DEFDS_1820 periplasmic nitrate reductase NapA; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Twin-arginine translocation pathway, signal sequence, subgroup; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Periplasmic nitrate reductase NapA YP_004602540.1 PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; KEGG: dap:Dacet_0085 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602541.1 KEGG: ddf:DEFDS_1818 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004602542.1 KEGG: ddf:DEFDS_1817 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602543.1 COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR006054:IPR006055:IPR013520; KEGG: ddf:DEFDS_0125 hypothetical protein; PFAM: Exonuclease, RNase T/DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit YP_004602544.1 PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR018658:IPR000031; KEGG: ddf:DEFDS_0021 hypothetical protein; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; Protein of unknown function DUF2089; SPTR: Putative uncharacterized protein YP_004602545.1 PFAM: AIR carboxylase; COGs: COG0293 23S rRNA methylase; HAMAP: Ribosomal RNA large subunit methyltransferase E; InterPro IPR002877; KEGG: ddf:DEFDS_0022 cell division protein methyltransferase FtsJ; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Cell division protein methyltransferase FtsJ YP_004602546.1 PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ; COGs: COG1530 Ribonuclease G and E; InterPro IPR004659:IPR003029:IPR019307; KEGG: cni:Calni_1377 RNase G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain; SPTR: RNAse G; TIGRFAM: Ribonuclease E/G YP_004602547.1 PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family; KEGG: ddf:DEFDS_0024 mutual gliding protein A; SPTR: Mutual gliding protein A YP_004602548.1 PFAM: ADP-ribosylation factor family; InterPro IPR004942; KEGG: cni:Calni_1375 roadblock/lc7 family protein; PFAM: Dynein light chain-related; SPTR: Roadblock/LC7 family protein YP_004602549.1 PFAM: Roadblock/LC7 domain; COGs: COG0353 Recombinational DNA repair protein (RecF pathway); HAMAP: Recombination protein recR; InterPro IPR000093:IPR006154:IPR015967:IPR006171; KEGG: cni:Calni_1374 DNA replication and repair protein RecR; PFAM: Toprim domain; Zinc finger C4-type, RecR; SMART: Toprim domain, subgroup; SPTR: DNA replication and repair protein RecR; TIGRFAM: RecR protein YP_004602550.1 PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR; COGs: COG0718 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0133; InterPro IPR004401; KEGG: ddf:DEFDS_0142 hypothetical protein; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein DEFDS_0142; TIGRFAM: Uncharacterised protein family UPF0133 YP_004602551.1 PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR012763:IPR003593:IPR003959; KEGG: ddf:DEFDS_0141 DNA polymerase III gamma/tau subunits; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: DNA polymerase III, gamma/tau subunits; TIGRFAM: DNA polymerase III, subunit gamma/ tau YP_004602552.1 PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunit gamma and tau; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602553.1 PFAM: Transposase DDE domain YP_004602554.1 KEGG: cni:Calni_1818 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602555.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001320:IPR001638; KEGG: cni:Calni_1817 amino acid abc transporter substrate-binding protein, paat family; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; Ionotropic glutamate receptor; SPTR: Amino acid ABC transporter substrate-binding protein, PAAT family YP_004602556.1 PFAM: Bacterial extracellular solute-binding proteins, family 3; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: ddf:DEFDS_2027 amino acid ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Amino acid ABC transporter, permease; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_004602557.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ddf:DEFDS_2026 amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid ABC transporter, ATP-binding protein YP_004602558.1 PFAM: ABC transporter; InterPro IPR001041; KEGG: ddf:DEFDS_2025 hypothetical protein; PFAM: Ferredoxin; SPTR: Putative uncharacterized protein YP_004602559.1 PFAM: 2Fe-2S iron-sulfur cluster binding domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ddf:DEFDS_0145 two-component response regulator; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component response regulator YP_004602560.1 PFAM: Response regulator receiver domain; COGs: COG1923 Uncharacterized host factor I protein; InterPro IPR005001:IPR001163; KEGG: ddf:DEFDS_0146 small nuclear ribonucleoprotein; PFAM: Like-Sm ribonucleoprotein, core; SPTR: Small nuclear ribonucleoprotein; TIGRFAM: Host factor Hfq YP_004602561.1 PFAM: LSM domain; TIGRFAM: RNA chaperone Hfq; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602563.1 PFAM: Nucleotidyltransferase domain; COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: chy:CHY_2535 hypothetical protein; PFAM: Protein of unknown function DUF86; SPTR: Putative toxin-antitoxin system, antitoxin component YP_004602564.1 PFAM: Protein of unknown function DUF86; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: vvu:VV2_0683 transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Transcriptional regulator YP_004602565.1 PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: glo:Glov_1530 TrkA-C domain protein; PFAM: Regulator of K+ conductance, C-terminal; Divalent ion symporter; SPTR: TrkA-C domain protein YP_004602566.1 PFAM: Citrate transporter; TrkA-C domain; COGs: COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; InterPro IPR006240:IPR000760; KEGG: nwa:Nwat_0721 3'(2'),5'-bisphosphate nucleotidase; PFAM: Inositol monophosphatase; SPTR: 3'(2'),5'-bisphosphate nucleotidase; TIGRFAM: 3(2),5 -bisphosphate nucleotidase, bacterial YP_004602567.1 PFAM: Inositol monophosphatase family; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase, bacterial; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; HAMAP: Sulfate adenylyltransferase subunit 2; InterPro IPR011784:IPR002500; KEGG: mca:MCA2629 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase subunit 2; TIGRFAM: Sulphate adenylyltransferase, small subunit YP_004602568.1 PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, small subunit; InterPro IPR008815; KEGG: sun:SUN_0718 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein YP_004602569.1 PFAM: S23 ribosomal protein; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; HAMAP: Sulfate adenylyltransferase subunit 1; InterPro IPR011779:IPR002891:IPR000795; KEGG: aeh:Mlg_2345 sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; PFAM: Adenylylsulphate kinase, C-terminal; Protein synthesis factor, GTP-binding; PRIAM: Sulfate adenylyltransferase., Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: Sulphate adenylyltransferase, large subunit; Adenylylsulphate kinase, C-terminal YP_004602570.1 PFAM: Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK); sulfate adenylyltransferase, large subunit; small GTP-binding protein domain; InterPro IPR001584; KEGG: ppd:Ppro_1841 integrase catalytic subunit; PFAM: Integrase, catalytic core; SPTR: Integrase, catalytic region YP_004602571.1 PFAM: Integrase core domain; InterPro IPR002514; KEGG: kol:Kole_0767 transposase IS3/IS911 family protein; PFAM: Transposase IS3/IS911; SPTR: Putative uncharacterized protein YP_004602572.1 PFAM: Transposase; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: tba:TERMP_00544 putative nucleotidyltransferase; PFAM: Nucleotidyltransferase; SPTR: Putative uncharacterized protein YP_004602573.1 PFAM: Nucleotidyltransferase domain; COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: kol:Kole_0232 protein of unknown function DUF86; PFAM: Protein of unknown function DUF86; SPTR: Putative uncharacterized protein YP_004602574.1 PFAM: Protein of unknown function DUF86; KEGG: ere:EUBREC_0492 hypothetical protein YP_004602575.1 COGs: COG5421 Transposase; InterPro IPR002559; KEGG: dal:Dalk_2552 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602576.1 PFAM: Transposase DDE domain; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: bpf:BpOF4_18990 putative major facilitator superfamily protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative major facilitator superfamily protein YP_004602577.1 PFAM: Major Facilitator Superfamily; COGs: COG1814 Uncharacterized membrane protein; InterPro IPR003251:IPR008217; KEGG: pmo:Pmob_0860 hypothetical protein; PFAM: Protein of unknown function DUF125, transmembrane; Rubrerythrin; SPTR: Putative uncharacterized protein YP_004602578.1 PFAM: VIT family; Rubrerythrin; COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: ddf:DEFDS_1443 signal transduction protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Signal transduction protein YP_004602579.1 PFAM: CBS domain; InterPro IPR013096; KEGG: ddf:DEFDS_1702 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein YP_004602580.1 PFAM: Cupin domain; InterPro IPR011701; KEGG: MFS general substrate transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1 YP_004602581.1 PFAM: Major Facilitator Superfamily; COGs: COG1942 Uncharacterized protein 4-oxalocrotonate tautomerase homolog; InterPro IPR018191:IPR004370; KEGG: dze:Dd1591_4074 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; SPTR: 4-oxalocrotonate tautomerase family enzyme; TIGRFAM: 4-oxalocrotonate tautomerase, subgroup YP_004602582.1 PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: tye:THEYE_A1086 hypothetical protein; PFAM: Uncharacterised protein family UPF0066; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0066 YP_004602583.1 PFAM: Uncharacterised protein family UPF0066; TIGRFAM: putative methyltransferase, YaeB/AF_0241 family; InterPro IPR001845; KEGG: ddf:DEFDS_0052 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family YP_004602584.1 PFAM: Bacterial regulatory protein, arsR family; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ddf:DEFDS_0053 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Putative uncharacterized protein YP_004602585.1 PFAM: Outer membrane efflux protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: ddf:DEFDS_0054 acriflavin resistance protein, AcrA/AcrE family; PFAM: Secretion protein HlyD; SPTR: Acriflavin resistance protein, AcrA/AcrE family; TIGRFAM: Secretion protein HlyD YP_004602586.1 PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: ddf:DEFDS_0055 acriflavin resistance protein, AcrB/AcrD/AcrF family; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein, AcrB/AcrD/AcrF family YP_004602587.1 PFAM: AcrB/AcrD/AcrF family; KEGG: ddf:DEFDS_0056 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602588.1 PFAM: Protein of unknown function (DUF2892); InterPro IPR011701; KEGG: dap:Dacet_2401 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1 YP_004602589.1 PFAM: Major Facilitator Superfamily; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: ddf:DEFDS_1609 hypothetical protein; PFAM: Patatin; SPTR: Putative uncharacterized protein YP_004602590.1 PFAM: Patatin-like phospholipase; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: ddf:DEFDS_1608 transcriptional regulator, GntR family; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family YP_004602591.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: ddf:DEFDS_1607 transcriptional regulator, GntR family; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family YP_004602592.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase PurS component; InterPro IPR003850; KEGG: ddf:DEFDS_1606 phosphoribosylformylglycinamidine synthase small subunit; PFAM: Phosphoribosylformylglycinamidine synthetase, PurS subunit; SPTR: Phosphoribosylformylglycinamidine synthase, small subunit; TIGRFAM: Phosphoribosylformylglycinamidine synthetase, PurS subunit YP_004602593.1 PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein; COGs: COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain; HAMAP: Phosphoribosylformylglycinamidine synthase 1; InterPro IPR010075:IPR011698; KEGG: cni:Calni_1057 phosphoribosylformylglycinamidine synthase subunit I; PFAM: CobB/CobQ-like glutamine amidotransferase; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase subunit I; TIGRFAM: Phosphoribosylformylglycinamidine synthase I YP_004602594.1 PFAM: CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: phosphoribosylformylglycinamidine synthase I; COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; HAMAP: Phosphoribosylformylglycinamidine synthase 2; InterPro IPR010074:IPR000728:IPR010918; KEGG: cni:Calni_1056 phosphoribosylformylglycinamidine synthase subunit II; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase 2; TIGRFAM: Phosphoribosylformylglycinamidine synthase II YP_004602595.1 PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase II; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854:IPR000583:IPR000836; KEGG: ddf:DEFDS_1603 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; Phosphoribosyltransferase; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: Amidophosphoribosyl transferase YP_004602596.1 PFAM: Phosphoribosyl transferase domain; Glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase; KEGG: cni:Calni_1054 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602597.1 COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: ddf:DEFDS_0528 caffeoyl-CoA O-methyltransferase; PFAM: O-methyltransferase, family 3; SPTR: Caffeoyl-CoA O-methyltransferase YP_004602598.1 PFAM: O-methyltransferase; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: cni:Calni_1780 peptidase U32; PFAM: Peptidase U32; SPTR: Peptidase U32 YP_004602599.1 PFAM: Peptidase family U32; COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); HAMAP: DNA ligase; InterProIPR001679:IPR013839:IPR004150:IPR004149:IPR 001357:IPR013840:IPR003583; KEGG: ddf:DEFDS_0530 NAD-dependent DNA ligase; PFAM: NAD-dependent DNA ligase, adenylation; NAD-dependent DNA ligase, OB-fold; Zinc-finger, NAD-dependent DNA ligase C4-type; BRCT; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase, N-terminal; Helix-hairpin-helix DNA-binding motif, class 1; BRCT; SPTR: DNA ligase; TIGRFAM: NAD-dependent DNA ligase YP_004602600.1 PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent; COGs: COG1806 conserved hypothetical protein; HAMAP: Protein of unknown function DUF299, phosphotransferase, predicted; InterPro IPR005177; KEGG: cni:Calni_1778 hypothetical protein; PFAM: Protein of unknown function DUF299, phosphotransferase, predicted; SPTR: Putative phosphotransferase Calni_1778 YP_004602601.1 PFAM: Domain of unknown function (DUF299); InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004602602.1 PFAM: Transposase DDE domain; KEGG: sat:SYN_03116 hypothetical protein; SPTR: Hypothetical exported protein YP_004602603.1 InterPro IPR002525:IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004602604.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: msv:Mesil_3173 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602605.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: ppn:Palpr_2333 glycosyl transferase, WecB/TagA/CpsF family; PFAM: Glycosyl transferase WecB/TagA/CpsF; PRIAM: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; SPTR: Putative acetyltransferase/glucosyltransferase; TIGRFAM: Glycosyl transferase WecB/TagA/CpsF YP_004602606.1 PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family; InterPro IPR018831; KEGG: dal:Dalk_1594 hypothetical protein; PFAM: Protein of unknown function NKWYS; SPTR: Putative uncharacterized protein YP_004602607.1 PFAM: Putative capsular polysaccharide synthesis protein; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ppn:Palpr_2332 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1 YP_004602608.1 PFAM: Glycosyl transferases group 1; KEGG: sli:Slin_6401 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602609.1 InterPro IPR000863; KEGG: dae:Dtox_4099 sulfotransferase; PFAM: Sulfotransferase; SPTR: Sulfotransferase YP_004602610.1 PFAM: Sulfotransferase domain; KEGG: eli:ELI_12210 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602611.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bse:Bsel_3040 glycosyl transferase family 2 protein; PFAM: Glycosyl transferase, family 2; SPTR: WfaY protein YP_004602612.1 PFAM: Glycosyl transferase family 2; COGs: COG2327 conserved hypothetical protein; KEGG: pca:Pcar_1801 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602613.1 PFAM: Polysaccharide pyruvyl transferase; InterPro IPR000863; KEGG: syp:SYNPCC7002_A1506 hypothetical protein; PFAM: Sulfotransferase; SPTR: Putative uncharacterized protein YP_004602614.1 PFAM: Sulfotransferase domain; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: dat:HRM2_25290 lipopolysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Lipopolysaccharide biosynthesis protein YP_004602615.1 PFAM: Polysaccharide biosynthesis protein YP_004602616.1 InterPro IPR008815; KEGG: fps:FP1126 hypothetical protein; PFAM: 23S rRNA-associated protein; SPTR: Putative uncharacterized protein YP_004602617.1 PFAM: S23 ribosomal protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: saf:SULAZ_0357 polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Polysaccharide biosynthesis protein CapD YP_004602618.1 PFAM: Polysaccharide biosynthesis protein; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: wsu:WS0037 aminotransferase-like protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: AMINOTRANSFERASE HOMOLOG YP_004602619.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: swp:swp_1585 sugar transferase; PFAM: Bacterial sugar transferase; SPTR: Sugar transferase YP_004602620.1 PFAM: Bacterial sugar transferase; InterPro IPR003674; KEGG: cni:Calni_0126 oligosaccharyl transferase STT3 subunit; PFAM: Oligosaccharyl transferase, STT3 subunit; SPTR: Oligosaccharyl transferase STT3 subunit YP_004602621.1 KEGG: sfu:Sfum_0792 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602622.1 PFAM: Sulfotransferase domain; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: rma:Rmag_0889 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, family 2 YP_004602623.1 PFAM: Glycosyl transferase family 2; InterPro IPR000863; KEGG: ter:Tery_3140 sulfotransferase; PFAM: Sulfotransferase; SPTR: Sulfotransferase YP_004602624.1 PFAM: Sulfotransferase domain; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: fph:Fphi_1480 putative teichuronic acid biosynthesis glycosyl transferase; PFAM: Glycosyl transferase, family 2; SPTR: WfdV YP_004602625.1 PFAM: Glycosyl transferase family 2; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: saf:SULAZ_1210 glycosyl transferase, family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyltransferase family 2 YP_004602626.1 PFAM: Glycosyl transferase family 2; SPTR: Putative uncharacterized protein YP_004602628.1 KEGG: dba:Dbac_0822 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602629.1 PFAM: Domain of unknown function (DUF1814); InterPro IPR000863; KEGG: ter:Tery_3140 sulfotransferase; PFAM: Sulfotransferase; SPTR: Sulfotransferase YP_004602630.1 PFAM: Sulfotransferase domain; KEGG: syr:SynRCC307_0197 hypothetical protein; SPTR: Putative uncharacterized protein SynRCC307_0197 YP_004602631.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: bfr:BF2582 capsular polysaccharide transporter; PFAM: Polysaccharide biosynthesis protein; SPTR: Capsular polysaccharide repeat unit transporter YP_004602632.1 PFAM: Polysaccharide biosynthesis protein; KEGG: fjo:Fjoh_0319 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602633.1 KEGG: cyc:PCC7424_4383 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602634.1 KEGG: ava:Ava_2392 putative carbamoylphosphate synthase large subunit short form; SPTR: Putative carbamoylphosphate synthase large subunit short form YP_004602635.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: DegT/DnrJ/eryc1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase YP_004602636.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005907:IPR005835; KEGG: son:SO_3186 glucose-1-phosphate-thymidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate thymidylyltransferase; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, long form YP_004602637.1 PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form; InterPro IPR008815; KEGG: gem:GM21_0610 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein YP_004602638.1 PFAM: S23 ribosomal protein YP_004602639.1 KEGG: sdl:Sdel_0830 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602640.1 KEGG: sdl:Sdel_0829 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602642.1 InterPro IPR008815; KEGG: fps:FP1126 hypothetical protein; PFAM: 23S rRNA-associated protein; SPTR: Putative uncharacterized protein YP_004602643.1 PFAM: S23 ribosomal protein; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: cni:Calni_1166 gdp-L-fucose synthase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-L-fucose synthase; SPTR: GDP-L-fucose synthase YP_004602644.1 PFAM: NAD dependent epimerase/dehydratase family; InterPro IPR008815; KEGG: cni:Calni_1165 hypothetical protein; PFAM: 23S rRNA-associated protein; SPTR: Putative uncharacterized protein YP_004602645.1 PFAM: S23 ribosomal protein; COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR006368:IPR001509; KEGG: gem:GM21_3149 GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase YP_004602646.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase; InterPro IPR008815; KEGG: sru:SRU_1288 hypothetical protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein YP_004602647.1 PFAM: S23 ribosomal protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: sua:Saut_2008 HEPN domain-containing protein; PFAM: HEPN; SMART: HEPN; SPTR: HEPN domain protein YP_004602648.1 PFAM: HEPN domain; InterPro IPR002934; KEGG: sua:Saut_2009 hypothetical protein; PFAM: Nucleotidyltransferase; SPTR: Putative uncharacterized protein YP_004602649.1 PFAM: Nucleotidyltransferase domain; COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR005886:IPR001509; KEGG: cni:Calni_0166 udp-galactose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase YP_004602650.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: dal:Dalk_2552 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602651.1 PFAM: Transposase DDE domain; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: ddf:DEFDS_1468 long-chain fatty-acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Long-chain fatty-acid-CoA ligase YP_004602652.1 PFAM: AMP-binding enzyme; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: ddf:DEFDS_1467 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Crotonase, core; SPTR: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase YP_004602653.1 PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: ddf:DEFDS_1466 3-ketoacyl-CoA thiolase; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: 3-ketoacyl-CoA thiolase; TIGRFAM: Thiolase YP_004602654.1 PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: ddf:DEFDS_1465 acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central region; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase YP_004602655.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain; COGs: COG0824 thioesterase; InterPro IPR006684:IPR006683; KEGG: thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily protein; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase YP_004602656.1 PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family; KEGG: ddf:DEFDS_1839 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602657.1 PFAM: Chalcone-flavanone isomerase YP_004602658.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: ddf:DEFDS_1835 3-hydroxybutyryl-CoA dehydratase; PFAM: Crotonase, core; PRIAM: 3-hydroxybutyryl-CoA dehydratase; SPTR: 3-hydroxybutyryl-CoA dehydratase YP_004602659.1 PFAM: Enoyl-CoA hydratase/isomerase family; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: ddf:DEFDS_1834 butyryl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central region; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Butyryl-CoA dehydrogenase YP_004602660.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: ddf:DEFDS_1833 iron-sulfur cluster-binding protein; PFAM: Cysteine-rich region, CCG; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Iron-sulfur cluster-binding protein YP_004602661.1 PFAM: Cysteine-rich domain; Nitrate reductase gamma subunit; COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: ddf:DEFDS_1832 electron transfer flavoprotein subunit beta; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein, beta subunit YP_004602662.1 PFAM: Electron transfer flavoprotein domain; COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: ddf:DEFDS_1831 electron transfer flavoprotein subunit alpha; PFAM: Electron transfer flavoprotein, alpha subunit, C-terminal; Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein, alpha subunit YP_004602663.1 PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: tye:THEYE_A0982 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 3-hydroxyisobutyrate dehydrogenase; SPTR: 3-hydroxyisobutyrate dehydrogenase YP_004602664.1 PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; KEGG: csh:Closa_3415 protein of unknown function DUF342; SPTR: Putative uncharacterized protein YP_004602665.1 PFAM: Protein of unknown function (DUF342); COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR006050:IPR005101; KEGG: sku:Sulku_1616 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, N-terminal; PRIAM: Deoxyribodipyrimidine photo-lyase; SPTR: Deoxyribodipyrimidine photo-lyase YP_004602666.1 PFAM: FAD binding domain of DNA photolyase; DNA photolyase; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: ddf:DEFDS_1618 Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, Rrf2 family YP_004602667.1 PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein; COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: ddf:DEFDS_1619 cytochrome bd oxidase subunit I; PFAM: Cytochrome bd ubiquinol oxidase, subunit I; SPTR: Cytochrome bd oxidase subunit I YP_004602668.1 PFAM: Bacterial Cytochrome Ubiquinol Oxidase; COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: ddf:DEFDS_1620 cytochrome bd oxidase subunit II; PFAM: Cytochrome bd ubiquinol oxidase, subunit II; SPTR: Cytochrome bd oxidase subunit II; TIGRFAM: Cytochrome bd ubiquinol oxidase, subunit II YP_004602669.1 PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB); KEGG: cni:Calni_0626 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602672.1 InterPro IPR002941; KEGG: cts:Ctha_1153 DNA methylase N-4/N-6 domain-containing protein; PFAM: DNA methylase N-4/N-6; SPTR: DNA methylase N-4/N-6 domain protein YP_004602673.1 PFAM: DNA methylase; InterPro IPR019045; KEGG: mja:MJ_1449 hypothetical protein; PFAM: Restriction endonuclease, type II, MjaII; PRIAM: Type II site-specific deoxyribonuclease; SPTR: Putative Type II restriction enzyme MjaII (Endonuclease MjaII) (R.MjaII) YP_004602674.1 PFAM: MjaII restriction endonuclease; KEGG: dap:Dacet_2661 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated YP_004602675.1 InterPro IPR006675:IPR006674:IPR003607; KEGG: dak:DaAHT2_1884 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG YP_004602676.1 PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004602677.1 KEGG: cch:Cag_0599 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602678.1 KEGG: pna:Pnap_4357 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602679.1 KEGG: sat:SYN_00500 metallo-beta-lactamase superfamily hydrolase; SPTR: Hydrolase of the metallo-beta-lactamase superfamily YP_004602680.1 KEGG: hypothetical protein; SPTR: Putative uncharacterized protein YP_004602681.1 KEGG: hch:HCH_05638 restriction endonuclease; SPTR: Predicted restriction endonuclease YP_004602682.1 KEGG: ddf:DEFDS_0872 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602683.1 KEGG: ddf:DEFDS_0871 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602685.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: dat:HRM2_17930 hypothetical protein; PFAM: Integrase, catalytic core, phage; SPTR: Putative uncharacterized protein YP_004602686.1 PFAM: Phage integrase family; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR014145:IPR002755; KEGG: mpd:MCP_2125 hypothetical protein; PFAM: DNA primase, small subunit; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase LigD, polymerase domain YP_004602687.1 TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain; COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterPro IPR012319:IPR015886; KEGG: gfo:GFO_3213 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding; PRIAM: DNA-formamidopyrimidine glycosylase; SPTR: Formamidopyrimidine-DNA glycosylase YP_004602688.1 PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg); COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027; KEGG: cni:Calni_1870 fad-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Glutamate synthase (NADPH); SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_004602689.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterPro IPR001041:IPR019574:IPR001450:IPR006656; KEGG: ddf:DEFDS_1612 molybdopterin oxidoreductase molybdopterin-binding subunit; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Molybdopterin oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Molybdopterin oxidoreductase, molybdopterin-binding subunit YP_004602690.1 PFAM: Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; InterPro IPR002559; KEGG: dal:Dalk_1317 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Isrso9-transposase protein YP_004602691.1 KEGG: glo:Glov_3666 transposase IS4 family protein; SPTR: Transposase IS4 family protein YP_004602692.1 PFAM: Transposase domain (DUF772); COGs: COG1001 Adenine deaminase; HAMAP: Adenine deaminase; InterPro IPR006679:IPR006680; KEGG: adenine deaminase; PFAM: Amidohydrolase 1; PRIAM: Adenine deaminase; SPTR: Adenine deaminase; TIGRFAM: Adenine deaminase YP_004602693.1 PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; COGs: COG2252 Permease; InterPro IPR006043; KEGG: shl:Shal_3171 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Probable transporter YP_004602694.1 PFAM: Permease family YP_004602695.1 COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR003346; KEGG: sfu:Sfum_2600 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS116/IS110/IS902; SPTR: Transposase IS116/IS110/IS902 YP_004602696.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; InterPro IPR019641; KEGG: nla:NLA_12350 hypothetical protein; PFAM: Protein of unknown function DUF2506; SPTR: Putative uncharacterized protein YP_004602697.1 PFAM: Protein of unknown function (DUF2628); manually curated YP_004602698.1 InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004602699.1 PFAM: Transposase DDE domain; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR020046:IPR020047:IPR001098:IPR 002421:IPR008918; KEGG: cni:Calni_1275 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease, N-terminal; Helix-hairpin-helix motif, class 2; DNA-directed DNA polymerase, family A, palm domain; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase 1 YP_004602700.1 PFAM: 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: ddf:DEFDS_1966 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted YP_004602701.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0141 Histidinol dehydrogenase; HAMAP: Histidinol dehydrogenase, prokaryotic-type; InterPro IPR012131; KEGG: ddf:DEFDS_1965 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase, prokaryotic-type; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: Histidinol dehydrogenase, prokaryotic-type YP_004602702.1 PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; InterPro IPR008258:IPR018392:IPR002482; KEGG: ddf:DEFDS_1862 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase-like, catalytic; Peptidoglycan-binding lysin domain; SPTR: Lytic transglycosylase, catalytic YP_004602703.1 PFAM: Transglycosylase SLT domain; LysM domain YP_004602704.1 PFAM: Elongation factor Tu C-terminal domain; Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU; HAMAP: Ribosomal protein L33; InterPro IPR001705; KEGG: ddf:DEFDS_1786 50S ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33 YP_004602705.1 PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004602706.1 PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial; COGs: COG0250 Transcription antiterminator; InterPro IPR001062:IPR006645:IPR005824; KEGG: dap:Dacet_0360 NusG antitermination factor; PFAM: Transcription antitermination protein, NusG, N-terminal; KOW; SMART: Transcription antitermination protein, NusG, N-terminal; KOW; SPTR: Transcription antitermination protein nusG; TIGRFAM: Transcription antitermination protein, NusG YP_004602707.1 PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG; COGs: COG0080 Ribosomal protein L11; InterPro IPR006519:IPR020784:IPR020783:IPR000911; KEGG: cni:Calni_1532 LSU ribosomal protein l11p; PFAM: Ribosomal protein L11, N-terminal; Ribosomal protein L11, C-terminal; SMART: Ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: Ribosomal protein L11, bacterial-type YP_004602708.1 PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11; COGs: COG0081 Ribosomal protein L1; InterPro IPR005878:IPR002143; KEGG: cni:Calni_1531 LSU ribosomal protein l1p; PFAM: Ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: Ribosomal protein L1, bacterial-type YP_004602709.1 PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast; COGs: COG0244 Ribosomal protein L10; HAMAP: 50S ribosomal protein L10; InterPro IPR001790; KEGG: ddf:DEFDS_1781 50S ribosomal protein L10; PFAM: Ribosomal protein L10; SPTR: 50S ribosomal protein L10 YP_004602710.1 PFAM: Ribosomal protein L10; COGs: COG0222 Ribosomal protein L7/L12; HAMAP: Ribosomal protein L7/L12; InterPro IPR000206:IPR013823; KEGG: ddf:DEFDS_1780 50S ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12, C-terminal; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: Ribosomal protein L7/L12 YP_004602711.1 PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12; COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; HAMAP: DNA-directed RNA polymerase subunit beta; InterProIPR010243:IPR007644:IPR007642:IPR007645:IPR 019462:IPR007120:IPR007641; KEGG: ddf:DEFDS_1779 DNA-directed RNA polymerase subunit beta; PFAM: DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 2; RNA polymerase, beta subunit, protrusion; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2, domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit, bacterial-type YP_004602712.1 PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit; COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; HAMAP: DNA-directed RNA polymerase subunit beta'; InterProIPR012754:IPR007080:IPR000722:IPR007066:IPR 007083:IPR007081:IPR006592; KEGG: ddf:DEFDS_1778 DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1, domain 1; RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; SMART: RNA polymerase, N-terminal; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime YP_004602713.1 PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form; COGs: COG0048 Ribosomal protein S12; InterPro IPR005679:IPR006032; KEGG: ddf:DEFDS_1777 30S ribosomal protein S12; PFAM: Ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: Ribosomal protein S12, bacterial-type YP_004602714.1 PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle; COGs: COG0049 Ribosomal protein S7; InterPro IPR005717:IPR000235; KEGG: ddf:DEFDS_1776 30S ribosomal protein S7; PFAM: Ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: Ribosomal protein S7, bacterial-type YP_004602715.1 PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle; COGs: COG0480 Translation elongation factors (GTPase); InterProIPR004540:IPR005225:IPR000795:IPR004161:IPR 005517:IPR000640; KEGG: ddf:DEFDS_1775 translation elongation factor G; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G 2; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein YP_004602716.1 PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; COGs: COG0050 GTPase - translation elongation factors; InterProIPR004160:IPR004541:IPR005225:IPR004161:IPR 000795; KEGG: ddf:DEFDS_1787 translation elongation factor Tu; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Elongation factor Tu; TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein YP_004602717.1 PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU; COGs: COG0051 Ribosomal protein S10; HAMAP: 30S ribosomal protein S10; InterPro IPR005731:IPR001848; KEGG: dap:Dacet_0371 30S ribosomal protein S10; PFAM: Ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: Ribosomal protein S10, bacterial YP_004602718.1 PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle; COGs: COG0087 Ribosomal protein L3; InterPro IPR019927:IPR000597; KEGG: ddf:DEFDS_1772 50S ribosomal protein L3; PFAM: Ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: Ribosomal protein L3, bacterial/organelle-type YP_004602719.1 PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial; COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: ddf:DEFDS_1771 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4 YP_004602720.1 PFAM: Ribosomal protein L4/L1 family; TIGRFAM: 50S ribosomal protein L4, bacterial/organelle; COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: cni:Calni_1505 LSU ribosomal protein l23p; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23 YP_004602721.1 PFAM: Ribosomal protein L23; COGs: COG0090 Ribosomal protein L2; InterPro IPR005880:IPR002171; KEGG: ddf:DEFDS_1769 50S ribosomal protein L2; PFAM: Ribosomal protein L2; SPTR: 50S ribosomal protein L2; TIGRFAM: Ribosomal protein L2, bacterial-type YP_004602722.1 PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar; COGs: COG0185 Ribosomal protein S19; InterPro IPR005732:IPR002222; KEGG: dap:Dacet_0376 30S ribosomal protein S19; PFAM: Ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: Ribosomal protein S19, bacterial-type YP_004602723.1 PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle; COGs: COG0091 Ribosomal protein L22; InterPro IPR005727:IPR001063; KEGG: ddf:DEFDS_1767 50S ribosomal protein L22; PFAM: Ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: Ribosomal protein L22, bacterial-type YP_004602724.1 PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type; COGs: COG0092 Ribosomal protein S3; InterProIPR005704:IPR008282:IPR004044:IPR001351:IPR 004087; KEGG: ddf:DEFDS_1766 30S ribosomal protein S3; PFAM: Ribosomal protein S3, C-terminal; Ribosomal protein S3, N-terminal; K Homology, type 2; SMART: K Homology; SPTR: 30S ribosomal protein S3; TIGRFAM: Ribosomal protein S3, bacterial YP_004602725.1 PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type; COGs: COG0197 Ribosomal protein L16/L10E; HAMAP: Ribosomal protein L16; InterPro IPR000114:IPR016180; KEGG: ddf:DEFDS_1765 50S ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: Ribosomal protein L16 YP_004602726.1 PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle; InterPro IPR001854; KEGG: cni:Calni_1499 ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: Ribosomal protein L29; TIGRFAM: Ribosomal protein L29 YP_004602727.1 PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; COGs: COG0186 Ribosomal protein S17; InterPro IPR019984:IPR000266; KEGG: dap:Dacet_0381 30S 30S ribosomal protein S17; PFAM: Ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: Ribosomal protein S17, bacterial-type YP_004602728.1 PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; COGs: COG0093 Ribosomal protein L14; InterPro IPR005745:IPR000218; KEGG: cni:Calni_1497 LSU ribosomal protein l14p; PFAM: Ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: Ribosomal protein L14, bacterial-type YP_004602729.1 PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle; COGs: COG0198 Ribosomal protein L24; InterPro IPR003256; KEGG: ddf:DEFDS_1761 50S ribosomal protein L24; SPTR: 50S ribosomal protein L24; TIGRFAM: Ribosomal protein L24 YP_004602730.1 TIGRFAM: ribosomal protein L24, bacterial/organelle; COGs: COG0094 Ribosomal protein L5; InterPro IPR002132; KEGG: ddf:DEFDS_1760 50S ribosomal protein L5; PFAM: Ribosomal protein L5; SPTR: 50S ribosomal protein L5 YP_004602731.1 PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5; COGs: COG0199 Ribosomal protein S14; InterPro IPR001209; KEGG: ddf:DEFDS_1759 30S ribosomal protein S14; PFAM: Ribosomal protein S14; SPTR: 30S ribosomal protein S14 type Z YP_004602732.1 PFAM: Ribosomal protein S14p/S29e; COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: ddf:DEFDS_1758 30S ribosomal protein S8; PFAM: Ribosomal protein S8; SPTR: 30S ribosomal protein S8 YP_004602733.1 PFAM: Ribosomal protein S8; COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR019906:IPR020040; KEGG: ddf:DEFDS_1757 50S ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: Ribosomal protein L6, bacterial-type YP_004602734.1 PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type; COGs: COG0256 Ribosomal protein L18; InterPro IPR004389:IPR005484; KEGG: ddf:DEFDS_1756 50S ribosomal protein L18; PFAM: Ribosomal protein L18/L5; SPTR: 50S ribosomal protein L18; TIGRFAM: Ribosomal protein L18, bacterial YP_004602735.1 PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type; COGs: COG0098 Ribosomal protein S5; InterPro IPR005712:IPR013810:IPR005324; KEGG: ddf:DEFDS_1755 30S ribosomal protein S5; PFAM: Ribosomal protein S5, N-terminal; Ribosomal protein S5, C-terminal; SPTR: 30S ribosomal protein S5; TIGRFAM: Ribosomal protein S5, bacterial-type YP_004602736.1 PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type; COGs: COG0200 Ribosomal protein L15; InterPro IPR005749:IPR001196; KEGG: dap:Dacet_0390 50S ribosomal protein L15; PFAM: Ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: Ribosomal protein L15, bacterial-type YP_004602737.1 PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle; COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: ddf:DEFDS_1753 preprotein translocase subunit Y; PFAM: SecY protein; SPTR: Preprotein translocase subunit Y; TIGRFAM: SecY protein YP_004602738.1 PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit; COGs: COG0563 Adenylate kinase and related kinase; HAMAP: Adenylate kinase; InterPro IPR006259:IPR000850:IPR007862; KEGG: ddf:DEFDS_1752 adenylate kinase; PFAM: Adenylate kinase; Adenylate kinase, zinc-finger lid region; SPTR: Adenylate kinase; TIGRFAM: Adenylate kinase, subfamily YP_004602739.1 PFAM: Adenylate kinase, active site lid; Adenylate kinase; TIGRFAM: adenylate kinases; COGs: COG0024 Methionine aminopeptidase; InterPro IPR002467:IPR000994; KEGG: ddf:DEFDS_1751 methionine aminopeptidase; PFAM: Peptidase M24, structural domain; PRIAM: Methionyl aminopeptidase; SPTR: Methionine aminopeptidase; TIGRFAM: Peptidase M24A, methionine aminopeptidase, subfamily 1 YP_004602740.1 PFAM: Metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I; COGs: COG0361 Translation initiation factor 1 (IF-1); HAMAP: Translation initiation factor IF-1; InterPro IPR004368:IPR006196; KEGG: has:Halsa_1899 translation initiation factor IF-1; PFAM: S1, IF1 type; SPTR: Translation initiation factor IF-1; TIGRFAM: Translation initiation factor IF-1 YP_004602741.1 PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1; HAMAP: Ribosomal protein L36; InterPro IPR000473; KEGG: ddf:DEFDS_1749 50S ribosomal protein L36; PFAM: Ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: Ribosomal protein L36 YP_004602742.1 PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; COGs: COG0099 Ribosomal protein S13; InterPro IPR019980:IPR001892; KEGG: ddf:DEFDS_1748 30S ribosomal protein S13; PFAM: Ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: Ribosomal protein S13, bacterial-type YP_004602743.1 PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13; COGs: COG0100 Ribosomal protein S11; InterPro IPR019981:IPR001971; KEGG: ddf:DEFDS_1747 30S ribosomal protein S11; PFAM: Ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: Ribosomal protein S11, bacterial-type YP_004602744.1 PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR005709:IPR001912:IPR002942; KEGG: ddf:DEFDS_1746 30S ribosomal protein S4; PFAM: Ribosomal protein S4; RNA-binding S4; SMART: RNA-binding S4; SPTR: 30S ribosomal protein S4; TIGRFAM: Ribosomal protein S4, bacterial-type YP_004602745.1 PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type; COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; HAMAP: DNA-directed RNA polymerase, alpha subunit; InterProIPR011773:IPR011261:IPR011262:IPR011260:IPR 011263; KEGG: dap:Dacet_0399 DNA-directed RNA polymerase, alpha subunit; PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; RNA polymerase, alpha subunit, C-terminal; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit YP_004602746.1 PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; COGs: COG0203 Ribosomal protein L17; HAMAP: 50S ribosomal protein L17; InterPro IPR000456; KEGG: ddf:DEFDS_1744 50S ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17 YP_004602747.1 PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: ddf:DEFDS_1743 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004602748.1 PFAM: ABC transporter; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ddf:DEFDS_1742 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004602749.1 PFAM: ABC transporter; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cni:Calni_1478 class II aldolase/adducin family protein; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Class II aldolase/adducin family protein YP_004602750.1 PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: cni:Calni_1476 abc transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004602751.1 PFAM: ABC transporter; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; InterPro IPR004639:IPR005814; KEGG: ddf:DEFDS_1739 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase YP_004602752.1 PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; KEGG: ddf:DEFDS_1738 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602753.1 KEGG: ddf:DEFDS_1737 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602754.1 PFAM: Putative F0F1-ATPase subunit (ATPase_gene1); InterPro IPR008413; KEGG: cni:Calni_1473 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602755.1 PFAM: ATP synthase I chain; COGs: COG0356 F0F1-type ATP synthase subunit a; HAMAP: ATP synthase subunit a; InterPro IPR000568; KEGG: ddf:DEFDS_1735 F0F1-type ATP synthase A subunit; PFAM: ATPase, F0 complex, subunit A; SPTR: ATP synthase subunit a; TIGRFAM: ATPase, F0 complex, subunit A YP_004602756.1 PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); HAMAP: ATPase, F0 complex, subunit C; InterPro IPR000454:IPR005953:IPR002379; KEGG: cni:Calni_1471 ATP synthase f0 subcomplex C subunit; PFAM: ATPase, F0/V0 complex, subunit C; SPTR: ATP synthase F0 subcomplex C subunit; TIGRFAM: ATPase, F0 complex, subunit C, bacterial/chloroplast YP_004602757.1 PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c; KEGG: ddf:DEFDS_1733 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004602758.1 PFAM: NapC/NirT cytochrome c family, N-terminal region; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: dap:Dacet_0423 rhomboid family protein; PFAM: Peptidase S54, rhomboid; SPTR: Rhomboid family protein YP_004602759.1 PFAM: Rhomboid family; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: ddf:DEFDS_1732 hydrogenase expression/formation protein HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC; SPTR: Hydrogenase expression/formation protein HupF/HypC; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC YP_004602760.1 PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: dap:Dacet_0421 hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein; SPTR: Hydrogenase formation HypD protein; TIGRFAM: Hydrogenase formation HypD protein YP_004602761.1 PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854:IPR000728:IPR010918; KEGG: cni:Calni_1467 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; SPTR: Hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE YP_004602762.1 PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE; KEGG: cni:Calni_1466 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602763.1 PFAM: Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496; KEGG: ddf:DEFDS_1729 phosphoribosyl-AMP cyclohydrolase; PFAM: Phosphoribosyl-AMP cyclohydrolase; PRIAM: Phosphoribosyl-AMP cyclohydrolase; SPTR: Phosphoribosyl-AMP cyclohydrolase YP_004602764.1 PFAM: Phosphoribosyl-AMP cyclohydrolase; COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883; KEGG: ddf:DEFDS_1728 type IV pilus assembly protein PilM; SPTR: Type IV pilus assembly protein PilM; TIGRFAM: Type IV pilus assembly protein PilM YP_004602765.1 PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM; COGs: COG3166 Tfp pilus assembly protein PilN; InterPro IPR007813; KEGG: ddf:DEFDS_1727 hypothetical protein; PFAM: Fimbrial assembly; SPTR: Putative uncharacterized protein YP_004602766.1 PFAM: Fimbrial assembly protein (PilN); KEGG: ddf:DEFDS_1726 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602767.1 PFAM: Pilus assembly protein, PilO; KEGG: cni:Calni_1461 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602768.1 PFAM: Pilus assembly protein, PilP; COGs: COG4796 Type II secretory pathway component HofQ; InterPro IPR013355:IPR005644:IPR004846; KEGG: ddf:DEFDS_1724 hypothetical protein; PFAM: Type II/III secretion system; NolW-like; SPTR: Putative uncharacterized protein; TIGRFAM: Type IV pilus secretin PilQ YP_004602769.1 PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein; TIGRFAM: type IV pilus secretin (or competence protein) PilQ YP_004602770.1 COGs: COG0763 Lipid A disaccharide synthetase; InterPro IPR003835; KEGG: ddf:DEFDS_1723 lipid A disaccharide synthetase; PFAM: Glycosyl transferase, family 19; PRIAM: Lipid-A-disaccharide synthase; SPTR: Lipid A disaccharide synthetase; TIGRFAM: Glycosyl transferase, family 19 YP_004602771.1 PFAM: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: hch:HCH_00126 short-chain alcohol dehydrogenase-like protein; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Short-chain alcohol dehydrogenase-like protein YP_004602772.1 PFAM: short chain dehydrogenase; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: ddf:DEFDS_1236 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein YP_004602773.1 PFAM: Uncharacterized protein family UPF0027; KEGG: cni:Calni_2043 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602774.1 COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: cni:Calni_2042 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase D-component YP_004602775.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731; KEGG: cni:Calni_2041 CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase YP_004602776.1 PFAM: BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative; COGs: COG2033 Desulfoferrodoxin; InterPro IPR002742; KEGG: cni:Calni_1945 superoxide reductase; PFAM: Desulfoferrodoxin, ferrous iron-binding region; PRIAM: Superoxide reductase; SPTR: Superoxide reductase; TIGRFAM: Desulfoferrodoxin, ferrous iron-binding region YP_004602777.1 PFAM: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin ferrous iron-binding domain; manually curated YP_004602778.1 PFAM: Protein of unknown function (DUF554); COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: ddf:DEFDS_1842 phospholipase D/transphosphatidylase; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase; SPTR: Phospholipase D/transphosphatidylase YP_004602779.1 PFAM: Polyphosphate kinase; Phospholipase D Active site motif; COGs: COG0218 GTPase; HAMAP: GTP-binding protein, ribosome biogenesis, YsxC; InterPro IPR019987:IPR005225:IPR002917; KEGG: dap:Dacet_0301 ribosome biogenesis GTP-binding protein YsxC; PFAM: GTP-binding protein, HSR1-related; SPTR: Ribosome biogenesis GTP-binding protein YsxC; TIGRFAM: GTP-binding protein, ribosome biogenesis, YsxC; Small GTP-binding protein YP_004602780.1 PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB; small GTP-binding protein domain; COGs: COG2404 phosphohydrolase (DHH superfamily); InterPro IPR003156; KEGG: cni:Calni_0881 phosphoesterase DHHA1; PFAM: Phosphoesterase, DHHA1; SPTR: Phosphoesterase DHHA1 YP_004602781.1 PFAM: DHH family; DHHA1 domain; This gene is disrupted by insertion of repetitive element; manually curated YP_004602782.1 PFAM: TrkA-N domain; TrkA-C domain; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: pmx:PERMA_0591 hypothetical protein; PFAM: Cation/H+ exchanger; SPTR: Putative uncharacterized protein YP_004602783.1 PFAM: Sodium/hydrogen exchanger family; COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: cni:Calni_0564 propionyl-CoA carboxylase carboxyltransferase subunit; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase carboxyltransferase subunit YP_004602784.1 PFAM: Carboxyl transferase domain; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: cni:Calni_0565 biotin carboxylase; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Biotin carboxylase YP_004602785.1 PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089; KEGG: ddf:DEFDS_1226 biotin carboxyl carrier protein; PFAM: Biotin/lipoyl attachment; SPTR: Biotin carboxyl carrier protein YP_004602786.1 PFAM: Biotin-requiring enzyme; COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR006159:IPR006099:IPR006158; KEGG: cni:Calni_0567 methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; Cobalamin (vitamin B12)-binding; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; Methylmalonyl-CoA mutase, C-terminal YP_004602787.1 PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: dap:Dacet_1929 LAO/AO transport system ATPase; PFAM: ArgK protein; SPTR: LAO/AO transport system ATPase; TIGRFAM: ArgK protein YP_004602788.1 PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase; COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: cni:Calni_0067 anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase-like; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase YP_004602789.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; InterPro IPR003658:IPR002645; KEGG: cni:Calni_0188 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist YP_004602790.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR004097; KEGG: cni:Calni_0065 inorganic diphosphatase; PFAM: Cystathionine beta-synthase, core; DHHA2; PRIAM: Inorganic diphosphatase; SPTR: Inorganic diphosphatase YP_004602791.1 PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain; COGs: COG0196 FAD synthase; InterPro IPR002606:IPR015864:IPR015865; KEGG: ddf:DEFDS_1953 riboflavin biosynthesis regulatory protein RibF; PFAM: FAD synthetase; Riboflavin kinase; PRIAM: FAD synthetase., Riboflavin kinase; SPTR: Riboflavin biosynthesis regulatory protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase YP_004602792.1 PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0621 2-methylthioadenine synthetase; HAMAP: Ribosomal protein S12 methylthiotransferase RimO; InterProIPR005840:IPR005839:IPR013848:IPR007197:IPR 006638; KEGG: cni:Calni_0476 SSU ribosomal protein s12p methylthiotransferase; PFAM: Methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: SSU ribosomal protein S12P methylthiotransferase; TIGRFAM: Ribosomal protein S12 methylthiotransferase RimO; Methylthiotransferase YP_004602793.1 PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; radical SAM methylthiotransferase, MiaB/RimO family; COGs: COG4105 DNA uptake lipoprotein; InterPro IPR017689:IPR019734; KEGG: cni:Calni_0477 outer membrane assembly lipoprotein yfio; SPTR: Outer membrane assembly lipoprotein YfiO; TIGRFAM: Outer membrane assembly lipoprotein YfiO YP_004602794.1 TIGRFAM: outer membrane assembly lipoprotein YfiO; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734; KEGG: ddf:DEFDS_1956 tetratricopeptide repeat protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide repeat protein YP_004602795.1 PFAM: Tetratricopeptide repeat; COGs: COG0172 Seryl-tRNA synthetase; HAMAP: Seryl-tRNA synthetase; InterPro IPR002317:IPR015866:IPR002314; KEGG: ddf:DEFDS_1957 seryl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Seryl-tRNA synthetase, class IIa, N-terminal; PRIAM: Serine--tRNA ligase; SPTR: Seryl-tRNA synthetase; TIGRFAM: Seryl-tRNA synthetase, class IIa YP_004602796.1 PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase; COGs: COG0313 methyltransferase; InterPro IPR000878; KEGG: ddf:DEFDS_1958 methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Methyltransferase YP_004602797.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: pmx:PERMA_1579 putative hydroxypyruvate reductase; PFAM: MOFRL; PRIAM: Glycerate kinase; SPTR: Putative hydroxypyruvate reductase YP_004602798.1 PFAM: MOFRL family; COGs: COG3238 conserved hypothetical protein; InterPro IPR006750; KEGG: ddf:DEFDS_1960 hypothetical protein; PFAM: Protein of unknown function DUF606; SPTR: Putative uncharacterized protein YP_004602799.1 PFAM: Protein of unknown function, DUF606; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: cni:Calni_1539 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family YP_004602800.1 PFAM: Bacterial regulatory protein, arsR family; InterPro IPR001845; KEGG: ddf:DEFDS_1673 AsrR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, AsrR family YP_004602801.1 PFAM: Bacterial regulatory protein, arsR family; manually curated YP_004602802.1 PFAM: Enterobacterial TraT complement resistance protein; KEGG: mtt:Ftrac_2644 UspA domain-containing protein; SPTR: UspA domain-containing protein YP_004602803.1 PFAM: Universal stress protein family; COGs: COG1292 Choline-glycine betaine transporter; InterPro IPR000060; KEGG: mtt:Ftrac_2905 choline/carnitine/betaine transporter; PFAM: BCCT transporter; SPTR: Choline/carnitine/betaine transporter; TIGRFAM: BCCT transporter YP_004602804.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport; COGs: COG2703 Hemerythrin; InterPro IPR012827:IPR012312; KEGG: cni:Calni_0209 hemerythrin-like metal-binding protein; PFAM: Haemerythrin/HHE cation-binding motif; SPTR: Hemerythrin-like metal-binding protein; TIGRFAM: Haemerythrin-like, metal-binding YP_004602805.1 PFAM: Hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain; COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: dap:Dacet_2548 cytochrome-c3 hydrogenase; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Cytochrome-c3 hydrogenase YP_004602806.1 PFAM: Nickel-dependent hydrogenase; COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR001821:IPR006311:IPR006137; KEGG: dap:Dacet_2547 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Hydrogenase (NiFe) small subunit HydA; TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence YP_004602807.1 PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR000160:IPR013767:IPR001633:IPR 001610; KEGG: dbr:Deba_0792 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS; PAC motif; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: Diguanylate cyclase, predicted; PAS YP_004602808.1 PFAM: EAL domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602809.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602810.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004602811.1 PFAM: Transposase DDE domain; COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR001638:IPR013767:IPR013656:IPR 003661:IPR003594:IPR001789:IPR001610; KEGG: gur:Gura_2743 PAS/PAC sensor hybrid histidine kinase; PFAM: Extracellular solute-binding protein, family 3; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; SMART: Extracellular solute-binding protein, family 3; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS YP_004602812.1 PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Bacterial extracellular solute-binding proteins, family 3; PAS fold; TIGRFAM: PAS domain S-box; KEGG: ddf:DEFDS_1274 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602813.1 KEGG: ddf:DEFDS_1273 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602814.1 PFAM: Bacterial type II secretion system protein G; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ddf:DEFDS_1272 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004602815.1 PFAM: ABC transporter; KEGG: bao:BAMF_0920 dephospho-CoA kinase dephosphocoenzyme A kinase; SPTR: Dephospho-CoA kinase Dephosphocoenzyme A kinase YP_004602816.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: cni:Calni_1032 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase YP_004602817.1 PFAM: Nitroreductase family; manually curated YP_004602818.1 PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179); KEGG: hypothetical protein; SPTR: Putative uncharacterized protein YP_004602819.1 COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: ddf:DEFDS_1578 glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase YP_004602820.1 PFAM: Glycerophosphoryl diester phosphodiesterase family; COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dap:Dacet_1135 coproporphyrinogen dehydrogenase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen dehydrogenase YP_004602821.1 PFAM: Radical SAM superfamily; HemN C-terminal region; manually curated YP_004602822.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: dap:Dacet_1969 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family YP_004602823.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: ddf:DEFDS_0209 BadM/Rrf2 family transcriptional regulator; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2 YP_004602824.1 PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR004511:IPR002500; KEGG: ppn:Palpr_2548 phosphoadenylyLSUlfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase; PRIAM: Phosphoadenylyl-sulfate reductase (thioredoxin); SPTR: Phosphoadenosine phosphosulfate reductase; TIGRFAM: Phosphoadenosine phosphosulphate reductase CysH-type YP_004602825.1 PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: thioredoxin-dependent adenylylsulfate APS reductase; phosophoadenylyl-sulfate reductase (thioredoxin); InterPro IPR010035:IPR003749; KEGG: cpb:Cphamn1_0643 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis YP_004602826.1 PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277; KEGG: ppn:Palpr_1214 cys/met metabolism pyridoxaL-phosphate-dependent protein; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_004602827.1 PFAM: Cys/Met metabolism PLP-dependent enzyme; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: cpb:Cphamn1_0645 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: UBA/THIF-type NAD/FAD binding protein YP_004602828.1 PFAM: MoeZ/MoeB domain; ThiF family; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: cpb:Cphamn1_0646 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1; SPTR: Mov34/MPN/PAD-1 family protein YP_004602829.1 PFAM: Mov34/MPN/PAD-1 family; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: wsu:WS1004 hypothetical protein; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; PRIAM: Ferredoxin--nitrite reductase; SPTR: Putative uncharacterized protein YP_004602830.1 PFAM: Nitrite and sulphite reductase 4Fe-4S domain; SirA-like protein; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878; KEGG: ddf:DEFDS_2056 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Uroporphyrinogen-III C-methyltransferase; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal YP_004602831.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); KEGG: cni:Calni_2122 siroheme synthase; SPTR: Siroheme synthase YP_004602832.1 TIGRFAM: siroheme synthase, N-terminal domain; InterPro IPR000866; KEGG: dap:Dacet_2447 redoxin domain protein; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Redoxin domain protein YP_004602833.1 PFAM: Redoxin; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; KEGG: ddf:DEFDS_1637 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602834.1 PFAM: NAD synthase; TIGRFAM: TIGR00268 family protein; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; HAMAP: tRNA-specific 2-thiouridylase; InterPro IPR004506:IPR018318; KEGG: cni:Calni_1891 tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; PFAM: tRNA methyl transferase-like; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA-specific 2-thiouridylase YP_004602835.1 PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; InterPro IPR007359; KEGG: ddf:DEFDS_0306 hypothetical protein; PFAM: Positive regulator of sigma(E), RseC/MucC; SPTR: Putative uncharacterized protein YP_004602836.1 PFAM: Positive regulator of sigma(E), RseC/MucC; COGs: COG0348 Polyferredoxin; KEGG: chy:CHY_2464 iron-sulfur cluster-binding protein; SPTR: Iron-sulfur cluster-binding protein YP_004602837.1 KEGG: tjr:TherJR_2284 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602838.1 COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: tjr:TherJR_2282 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein YP_004602839.1 PFAM: Cytochrome C assembly protein; TIGRFAM: c-type cytochrome biogenesis protein CcmF; COGs: COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes; KEGG: tjr:TherJR_2281 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602840.1 PFAM: Cytochrome C biogenesis protein; KEGG: chy:CHY_1386 hypothetical protein; SPTR: Conserved domain protein YP_004602843.1 KEGG: tjr:TherJR_2193 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602844.1 PFAM: Predicted membrane protein (DUF2318); COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: tjr:TherJR_2191 protein of unknown function DUF214; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein YP_004602845.1 PFAM: Predicted permease; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sso:SSO0688 ABC transporter, ATP binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004602846.1 PFAM: ABC transporter; InterPro IPR003838; KEGG: mac:MA1674 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein YP_004602847.1 PFAM: Predicted permease; KEGG: cni:Calni_1066 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602848.1 PFAM: DSBA-like thioredoxin domain; InterPro IPR011462; KEGG: caa:Caka_2052 protein of unknown function DUF1568; SPTR: Putative uncharacterized protein YP_004602849.1 PFAM: Transposase IS200 like; manually curated YP_004602850.1 PFAM: HTH domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: BirA biotin operon repressor domain; birA, biotin-[acetyl-CoA-carboxylase] ligase region; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005815:IPR005814; KEGG: adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; biotin synthase; PFAM: Aminotransferase class-III; PRIAM: Adenosylmethionine--8-amino-7-oxononanoate transaminase; SPTR: Adenosylmethionine-8-amino-7-oxononanoate transaminase; TIGRFAM: Adenosylmethionine--8-amino-7-oxononanoate aminotransferase YP_004602851.1 PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; COGs: COG0132 Dethiobiotin synthetase; HAMAP: Dethiobiotin synthase; InterPro IPR004472; KEGG: dha:DEHA2G24772g DEHA2G24772p; PRIAM: Dethiobiotin synthase; SPTR: Dethiobiotin synthetase; TIGRFAM: Dethiobiotin synthase YP_004602852.1 TIGRFAM: dethiobiotin synthase; COGs: COG0502 Biotin synthase; HAMAP: Biotin synthase; InterPro IPR002684:IPR007197:IPR010722:IPR006638; KEGG: dol:Dole_0682 biotin synthase; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; PRIAM: Biotin synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; TIGRFAM: Biotin synthase YP_004602853.1 PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: ddf:DEFDS_1301 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase, class I/II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: 8-amino-7-oxononanoate synthase YP_004602854.1 PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; KEGG: ddf:DEFDS_1302 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602855.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: ddf:DEFDS_1303 biotin biosynthesis protein BioC; PFAM: Methyltransferase type 11; SPTR: Biotin biosynthesis protein BioC YP_004602856.1 PFAM: Methyltransferase domain; TIGRFAM: biotin biosynthesis protein BioC; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: cni:Calni_0437 O-acetylhomoserine sulfhydrolase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine sulfhydrolase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase YP_004602857.1 PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: cni:Calni_0436 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A YP_004602858.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; KEGG: dat:HRM2_02200 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602859.1 KEGG: cni:Calni_0020 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602861.1 KEGG: gur:Gura_1104 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602862.1 This gene is disrupted by insertion of repetitive element; manually curated YP_004602863.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG3267 Type II secretory pathway component ExeA (predicted ATPase); InterPro IPR003593; KEGG: gur:Gura_1106 AAA ATPase; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase YP_004602864.1 PFAM: Archaeal ATPase; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR013563:IPR003593:IPR010066; KEGG: hch:HCH_00010 dipeptide/oligopeptide/nickel ABC transporter ATPase; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide transport ATP-binding protein AppF; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal YP_004602865.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR010158; KEGG: azl:AZL_d01280 beta-ureidopropionase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-carbamoyl-L-amino-acid hydrolase; SPTR: Beta-ureidopropionase; TIGRFAM: Amidase, hydantoinase/carbamoylase; tmRNA as predicted by Rfam (RF00023), score 217.09 YP_004602866.1 PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidase, hydantoinase/carbamoylase family; COGs: COG0691 tmRNA-binding protein; HAMAP: SsrA-binding protein; InterPro IPR000037; KEGG: ddf:DEFDS_1882 SsrA RNA (tmRNA)-binding protein; PFAM: SsrA-binding protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein YP_004602867.1 PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004602868.1 PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase; COGs: COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis; HAMAP: ATP phosphoribosyltransferase regulatory subunit; InterPro IPR002314; KEGG: ddf:DEFDS_2123 ATP phosphoribosyltransferase regulatory subunit; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; PRIAM: Histidine--tRNA ligase; SPTR: ATP phosphoribosyltransferase regulatory subunit YP_004602869.1 PFAM: tRNA synthetase class II core domain (G, H, P, S and T); COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: cni:Calni_0373 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--glyoxylate transaminase; SPTR: Aminotransferase class V YP_004602870.1 PFAM: Aminotransferase class-V; InterPro IPR018649; KEGG: pin:Ping_1904 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein YP_004602871.1 PFAM: Predicted membrane protein (DUF2078); COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: histidine kinase A domain-containing protein; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Histidine kinase A domain protein YP_004602872.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: ddf:DEFDS_2111 two-component system, NtrC family, transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two-component system, NtrC family, transcriptional regulator YP_004602873.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR000362:IPR009049; KEGG: dap:Dacet_2886 argininosuccinate lyase; PFAM: Fumarate lyase; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase YP_004602874.1 PFAM: Lyase; TIGRFAM: argininosuccinate lyase; KEGG: cni:Calni_0196 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602875.1 KEGG: ddf:DEFDS_2108 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602876.1 COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: cni:Calni_0405 gtp cyclohydrolase I; PFAM: Protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase folE2; TIGRFAM: Protein of unknown function DUF198 YP_004602877.1 PFAM: Uncharacterized ACR, COG1469; TIGRFAM: TIGR00294 family protein; COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR008910:IPR006685; KEGG: ddf:DEFDS_1276 mechanosensitive ion channel, MscS family; PFAM: Mechanosensitive ion channel MscS; Conserved TM helix; SPTR: Mechanosensitive ion channel, MscS family YP_004602878.1 PFAM: Mechanosensitive ion channel; Conserved TM helix; KEGG: dap:Dacet_1137 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602879.1 COGs: COG1826 Sec-independent protein secretion pathway components; HAMAP: Twin-arginine translocation protein TatA/E; InterPro IPR003369:IPR006312; KEGG: ddf:DEFDS_2139 twin-arginine translocation system component TatB; PFAM: Bacterial sec-independent translocation protein mttA/Hcf106; SPTR: Sec-independent protein translocase protein tatA/E homolog 2 YP_004602880.1 PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family; twin arginine-targeting protein translocase TatB; COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033:IPR019822; KEGG: ddf:DEFDS_2140 twin-arginine translocation system component TatC; PFAM: Sec-independent periplasmic protein translocase; SPTR: Twin-arginine translocation system component TatC; TIGRFAM: Twin arginine-targeting protein translocase, TatC YP_004602881.1 PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR010505:IPR006638:IPR013483; KEGG: cni:Calni_1795 gtp cyclohydrolase subunit MoaA; PFAM: Molybdenum cofactor synthesis C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: Molybdenum cofactor biosynthesis protein A YP_004602882.1 PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: ddf:DEFDS_2142 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein YP_004602883.1 PFAM: Uncharacterized conserved protein (DUF2088); COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602884.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG5421 Transposase; InterPro IPR002559; KEGG: msv:Mesil_3173 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602885.1 PFAM: Transposase DDE domain; KEGG: dap:Dacet_2499 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602886.1 PFAM: Protein of unknown function (DUF456); COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: ddf:DEFDS_2161 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602887.1 PFAM: Metallo-beta-lactamase superfamily YP_004602888.1 manually curated YP_004602889.1 KEGG: ddf:DEFDS_0190 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602890.1 PFAM: Protein of unknown function (DUF1049); COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: ddf:DEFDS_0189 histidine triad family protein; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad family protein YP_004602891.1 PFAM: HIT domain; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: ddf:DEFDS_0188 transcription regulator, Sir2 family; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Transcription regulator, Sir2 family YP_004602892.1 PFAM: Sir2 family; COGs: COG0679 permease; InterPro IPR004776; KEGG: ddf:DEFDS_0071 hypothetical protein; PFAM: Auxin efflux carrier; SPTR: Auxin Efflux Carrier YP_004602893.1 PFAM: Membrane transport protein; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757; KEGG: toc:Toce_0722 copper-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter YP_004602894.1 PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2608 Copper chaperone; InterPro IPR006121:IPR006122; KEGG: nth:Nther_1097 copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper ion binding protein; TIGRFAM: Copper ion-binding YP_004602895.1 PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: cdl:CDR20291_2619 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Putative uncharacterized protein YP_004602896.1 PFAM: Uncharacterised BCR, COG1937; COGs: COG0289 Dihydrodipicolinate reductase; HAMAP: Dihydrodipicolinate reductase; InterPro IPR000846:IPR011770; KEGG: dap:Dacet_2492 dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: Dihydrodipicolinate reductase, bacterial/plant YP_004602897.1 PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase; COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; HAMAP: Dihydrodipicolinate synthase; InterPro IPR002220:IPR005263; KEGG: ddf:DEFDS_0215 dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: Dihydrodipicolinate synthase subfamily YP_004602898.1 PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase; COGs: COG0253 Diaminopimelate epimerase; HAMAP: Diaminopimelate epimerase; InterPro IPR001653; KEGG: ddf:DEFDS_0214 diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; SPTR: Diaminopimelate epimerase; TIGRFAM: Diaminopimelate epimerase YP_004602899.1 PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: dap:Dacet_2487 hydrogenase maturation protease; PFAM: Peptidase A31, hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogen uptake protein YP_004602900.1 PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease; COGs: COG1969 Ni Fe-hydrogenase I cytochrome b subunit; InterPro IPR011577:IPR000516; KEGG: cni:Calni_0098 ni/fe-hydrogenase, b-type cytochrome subunit; SPTR: Ni/Fe-hydrogenase, b-type cytochrome subunit; TIGRFAM: Nickel-dependent hydrogenase b-type cytochrome subunit YP_004602901.1 PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: ddf:DEFDS_0076 Ni-Fe hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Ni-Fe hydrogenase, large subunit YP_004602902.1 PFAM: Nickel-dependent hydrogenase; COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137:IPR001821:IPR006311; KEGG: ddf:DEFDS_0077 Ni-Fe hydrogenase small subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Ni-Fe hydrogenase, small subunit; TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence YP_004602903.1 PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA); COGs: COG2518 Protein-L-isoaspartate carboxylmethyltransferase; InterPro IPR000682; KEGG: ddf:DEFDS_1899 protein-L-isoaspartate (D-aspartate) O-methyltransferase; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase; PRIAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase; SPTR: Protein-L-isoaspartate O-methyltransferase; TIGRFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_004602904.1 PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: ddf:DEFDS_1900 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; SPTR: Nicotinate phosphoribosyltransferase YP_004602905.1 PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase; COGs: COG3769 hydrolase (HAD superfamily); InterPro IPR013200:IPR006381:IPR006379; KEGG: pmx:PERMA_1578 mannosyl-3-phosphoglycerate phosphatase; PFAM: HAD superfamily hydrolase-like, type 3; PRIAM: Mannosyl-3-phosphoglycerate phosphatase; SPTR: Glucosyl-3-phosphoglycerate phosphatase; TIGRFAM: HAD-superfamily hydrolase, superfamily IIB, YedP; HAD-superfamily hydrolase, subfamily IIB YP_004602906.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily IIB; mannosyl-3-phosphoglycerate phosphatase; KEGG: ddf:DEFDS_0171 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602907.1 COGs: COG0114 Fumarase; HAMAP: Fumarate hydratase class II; InterPro IPR000362:IPR018951; KEGG: cni:Calni_0380 fumarase; PFAM: Fumarate lyase; Fumarase C, C-terminal; PRIAM: Fumarate hydratase; SPTR: Fumarase YP_004602908.1 PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: aspartate ammonia-lyase; fumarate hydratase, class II; COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR003714:IPR006596; KEGG: ddf:DEFDS_0226 phosphate starvation-induced protein; PFAM: PhoH-like protein; SMART: Nucleotide binding protein, PINc; SPTR: Phosphate starvation-induced protein YP_004602909.1 PFAM: PhoH-like protein; COGs: COG0279 Phosphoheptose isomerase; HAMAP: Phosphoheptose isomerase; InterPro IPR020620; KEGG: ddf:DEFDS_0227 phosphoheptose isomerase; SPTR: Phosphoheptose isomerase YP_004602910.1 PFAM: SIS domain; TIGRFAM: phosphoheptose isomerase; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR004820:IPR004821; KEGG: ddf:DEFDS_0228 glycerol-3-phosphate cytidyltransferase; PFAM: Cytidylyltransferase; SPTR: Glycerol-3-phosphate cytidyltransferase; TIGRFAM: Cytidyltransferase-related YP_004602911.1 PFAM: Cytidylyltransferase; TIGRFAM: rfaE bifunctional protein, domain II; cytidyltransferase-related domain; COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR003711:IPR011545:IPR001650:IPR005118:IPR 014001:IPR004576; KEGG: cni:Calni_1739 transcription-repair coupling factor; PFAM: Transcription factor CarD; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Transcription-repair-coupling factor; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Transcription-repair coupling factor; TIGRFAM: Transcription-repair coupling factor YP_004602912.1 PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd); InterPro IPR000297; KEGG: cni:Calni_0078 ppic-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase YP_004602913.1 PFAM: PPIC-type PPIASE domain; InterPro IPR015391; KEGG: ddf:DEFDS_0231 peptidyl-prolyl cis-trans isomerase SurA; PFAM: SurA N-terminal; SPTR: Peptidyl-prolyl cis-trans isomerase SurA YP_004602914.1 PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; COGs: COG2262 GTPase; InterPro IPR002917:IPR016496; KEGG: cni:Calni_0703 gtp-binding protein HflX; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding protein HflX; TIGRFAM: GTP-binding protein, HflX; manually curated YP_004602915.1 PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cni:Calni_0454 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Putative uncharacterized protein YP_004602916.1 PFAM: Response regulator receiver domain; COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: ddf:DEFDS_0271 hypothetical protein; PFAM: Outer membrane lipoprotein carrier protein LolA; SPTR: Putative uncharacterized protein YP_004602917.1 PFAM: Outer membrane lipoprotein carrier protein LolA; TIGRFAM: periplasmic chaperone LolA; COGs: COG1663 Tetraacyldisaccharide-1-P 4'-kinase; HAMAP: Tetraacyldisaccharide 4'-kinase; InterPro IPR003758; KEGG: ddf:DEFDS_0341 tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide 4'-kinase; PRIAM: Tetraacyldisaccharide 4'-kinase; SPTR: Tetraacyldisaccharide 4'-kinase; TIGRFAM: Tetraacyldisaccharide 4'-kinase YP_004602918.1 PFAM: Tetraacyldisaccharide-1-P 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase; manually curated YP_004602919.1 PFAM: Transposase DDE domain; KEGG: ddf:DEFDS_0342 rubrerythrin domain protein; SPTR: Rubrerythrin domain protein YP_004602920.1 PFAM: Rubrerythrin; InterPro IPR003748; KEGG: hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein YP_004602921.1 PFAM: Uncharacterised ArCR, COG2043; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602922.1 InterPro IPR007272; KEGG: glo:Glov_1576 protein of unknown function DUF395 YeeE/YedE; PFAM: Protein of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein YP_004602923.1 PFAM: YeeE/YedE family (DUF395); KEGG: gsu:GSU1054 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602924.1 PFAM: SirA-like protein; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR013767:IPR003594:IPR001789:IPR000014; KEGG: dal:Dalk_3513 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; PAS; Signal transduction response regulator, receiver region; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS YP_004602925.1 PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; KEGG: ddf:DEFDS_1682 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602926.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2155); COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: ddf:DEFDS_0915 fumarate hydratase class I subunit beta; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I, beta subunit; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region YP_004602927.1 PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: ddf:DEFDS_0916 fumarate hydratase class I subunit alpha; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I, alpha subunit; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region YP_004602928.1 PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region; COGs: COG1049 Aconitase B; InterPro IPR015929:IPR001030:IPR004406; KEGG: ddf:DEFDS_0917 aconitate hydratase; PFAM: Aconitase B, N-terminal, bacterial; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: Aconitate hydratase 2; TIGRFAM: Aconitase B, bacterial YP_004602929.1 PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: gsu:GSU1465 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_004602930.1 PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; COGs: COG0039 Malate/lactate dehydrogenase; HAMAP: Malate dehydrogenase, NAD-dependent; InterPro IPR001236:IPR011275; KEGG: ddf:DEFDS_0919 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: Malate dehydrogenase; TIGRFAM: Malate dehydrogenase, NAD-dependent YP_004602931.1 PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent; COGs: COG0045 Succinyl-CoA synthetase beta subunit; HAMAP: Succinyl-CoA ligase [ADP-forming] subunit beta; InterPro IPR013650:IPR005811:IPR005809; KEGG: ddf:DEFDS_0920 succinyl-CoA synthase subunit beta; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA ligase [ADP-forming] subunit beta; TIGRFAM: Succinyl-CoA synthetase, beta subunit YP_004602932.1 PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR003781:IPR005811:IPR005810; KEGG: ddf:DEFDS_0921 succinyl-CoA synthase subunit alpha; PFAM: ATP-citrate lyase/succinyl-CoA ligase; CoA-binding; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA ligase [ADP-forming] subunit alpha; TIGRFAM: Succinyl-CoA ligase, alpha subunit YP_004602933.1 PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, alpha subunit; InterPro IPR001450; KEGG: ddf:DEFDS_0922 2-oxoglutarate ferredoxin oxidoreductase subunit delta; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, delta subunit YP_004602934.1 PFAM: 4Fe-4S binding domain; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: ddf:DEFDS_0923 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit YP_004602935.1 PFAM: domain; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: ddf:DEFDS_0924 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, beta subunit YP_004602936.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: ddf:DEFDS_0925 2-oxoglutarate ferredoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit YP_004602937.1 PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; InterPro IPR005631; KEGG: cni:Calni_0411 hypothetical protein; PFAM: Protein of unknown function DUF339; SPTR: Putative uncharacterized protein YP_004602938.1 PFAM: Protein of unknown function (DUF339); COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: ddf:DEFDS_0685 succinate dehydrogenase iron-sulfur protein; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: Succinate dehydrogenase, iron-sulfur protein; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein YP_004602939.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR011281:IPR014006; KEGG: ddf:DEFDS_0686 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: Succinate dehydrogenase, flavoprotein subunit; TIGRFAM: Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit YP_004602940.1 PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup; KEGG: ddf:DEFDS_0687 succinate dehydrogenase hydrophobic membrane anchor protein; SPTR: Succinate dehydrogenase, hydrophobic membrane anchor protein YP_004602941.1 PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; InterPro IPR014314; KEGG: ddf:DEFDS_0688 succinate dehydrogenase cytochrome b subunit; SPTR: Succinate dehydrogenase, cytochrome b subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit YP_004602942.1 PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602943.1 InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602944.1 PFAM: Transposase DDE domain; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR005580:IPR014001; KEGG: cni:Calni_1003 dead/deah box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; DbpA, RNA-binding; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein YP_004602945.1 PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: carbonate dehydratase; PFAM: Carbonic anhydrase; PRIAM: Carbonate dehydratase; SPTR: Carbonate dehydratase YP_004602946.1 PFAM: Carbonic anhydrase; COGs: COG3884 Acyl-ACP thioesterase; InterPro IPR002864; KEGG: cni:Calni_1199 acyl-acp thioesterase; PFAM: Acyl-ACP thioesterase; SPTR: Acyl-ACP thioesterase YP_004602947.1 PFAM: Acyl-ACP thioesterase YP_004602948.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ddf:DEFDS_1137 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Putative uncharacterized protein YP_004602949.1 PFAM: Glycosyl transferases group 1; InterPro IPR001296; KEGG: ddf:DEFDS_1138 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase YP_004602950.1 PFAM: Glycosyl transferases group 1; COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR001538; KEGG: tba:TERMP_00025 mannose-1-phosphate guanylyltransferase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; SPTR: Putative uncharacterized protein YP_004602951.1 PFAM: Mannose-6-phosphate isomerase; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: cni:Calni_0784 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein YP_004602952.1 PFAM: Metallo-beta-lactamase superfamily; InterPro IPR018961; KEGG: ddf:DEFDS_0621 hypothetical protein; PFAM: DnaJ homologue, subfamily C, member 28, conserved domain; SPTR: Putative uncharacterized protein YP_004602953.1 PFAM: Domain of unknown function (DUF1992); COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: ddf:DEFDS_1852 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; GntR, C-terminal; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family YP_004602954.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: mmh:Mmah_0483 L-lysine 2,3-aminomutase; PFAM: Radical SAM; PRIAM: Lysine 2,3-aminomutase; SPTR: L-lysine 2,3-aminomutase; TIGRFAM: Protein of unknown function DUF160 YP_004602955.1 PFAM: Lysine-2,3-aminomutase; TIGRFAM: KamA family protein; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146; KEGG: tac:Ta1498 glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Probable glutamine synthetase YP_004602956.1 PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: cni:Calni_0901 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Dihydroorotase; SPTR: Dihydroorotase; TIGRFAM: Dihydroorotase multifunctional complex type YP_004602957.1 PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: ddf:DEFDS_0841 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic YP_004602958.1 PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; HAMAP: Bifunctional protein pyrR; InterPro IPR000836; KEGG: ddf:DEFDS_0842 bifunctional pyrimidine biosynthesis protein PyrR; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Bifunctional protein pyrR YP_004602959.1 PFAM: Phosphoribosyl transferase domain; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002932; KEGG: glutamate synthase (NADPH) GltB2 subunit; PFAM: Glutamate synthase, central-C; SPTR: Ferredoxin-dependent glutamate synthase YP_004602960.1 PFAM: Conserved region in glutamate synthase; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004602961.1 PFAM: Transposase domain (DUF772); COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005671; KEGG: ddf:DEFDS_1662 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: 2-isopropylmalate synthase; SPTR: 2-isopropylmalate synthase; TIGRFAM: Bacterial 2-isopropylmalate synthase YP_004602962.1 PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase, bacterial type; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462:IPR004533; KEGG: cni:Calni_0491 cdp-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase YP_004602963.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; COGs: COG0688 Phosphatidylserine decarboxylase; HAMAP: Phosphatidylserine decarboxylase proenzyme; InterPro IPR003817:IPR004428; KEGG: ddf:DEFDS_1664 phosphatidylserine decarboxylase; PFAM: Phosphatidylserine decarboxylase-related; PRIAM: Phosphatidylserine decarboxylase; SPTR: Phosphatidylserine decarboxylase; TIGRFAM: Phosphatidylserine decarboxylase-related protein YP_004602964.1 PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein; manually curated YP_004602965.1 PFAM: Transposase DDE domain; Transposase domain (DUF772) YP_004602966.1 COGs: COG0059 Ketol-acid reductoisomerase; HAMAP: Ketol-acid reductoisomerase; InterPro IPR013116:IPR000506:IPR013023; KEGG: ddf:DEFDS_1665 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic; Acetohydroxy acid isomeroreductase C-terminal; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: Acetohydroxy acid isomeroreductase YP_004602967.1 PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: ddf:DEFDS_1666 acetolactate synthase small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit YP_004602968.1 PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766:IPR012846; KEGG: ddf:DEFDS_1667 acetolactate synthase large subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic YP_004602969.1 PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR000581:IPR004404; KEGG: ddf:DEFDS_1668 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase YP_004602970.1 PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; InterPro IPR002514; KEGG: kol:Kole_0767 transposase IS3/IS911 family protein; PFAM: Transposase IS3/IS911; SPTR: Putative uncharacterized protein YP_004602971.1 PFAM: Transposase; InterPro IPR001584; KEGG: ppd:Ppro_1841 integrase catalytic subunit; PFAM: Integrase, catalytic core; SPTR: Integrase, catalytic region YP_004602972.1 PFAM: Integrase core domain; COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR000583; KEGG: tcx:Tcr_1692 glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: Glutamine amidotransferase, class-II; PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine--fructose-6-phosphate transaminase YP_004602973.1 PFAM: Glutamine amidotransferases class-II; This gene is disrupted by insertion of repetitive element; manually curated YP_004602974.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: mac:MA2579 transposase; PFAM: Integrase, catalytic core; SPTR: Transposase, IS21 YP_004602975.1 PFAM: Integrase core domain; manually curated YP_004602976.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); manually curated YP_004602977.1 PFAM: IstB-like ATP binding protein; COGs: COG4584 Transposase and inactivated derivatives; KEGG: toc:Toce_1959 integrase catalytic region; SPTR: Integrase catalytic region YP_004602978.1 PFAM: Integrase core domain; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004602979.1 PFAM: Transposase DDE domain; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR019554; KEGG: sat:SYN_02695 polysaccharide export periplasmic protein; PFAM: Soluble ligand binding domain; SPTR: Periplasmic protein involved in polysaccharide export YP_004602980.1 PFAM: SLBB-domain like (DUF1017); Polysaccharide biosynthesis/export protein; SLBB domain; InterPro IPR003856; KEGG: svo:SVI_1467 chain length determinant protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: Chain length determinant protein YP_004602981.1 PFAM: Chain length determinant protein; KEGG: nde:NIDE0888 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602982.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: dap:Dacet_2770 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region YP_004602983.1 PFAM: Glycosyl transferase family 4; InterPro IPR007165; KEGG: ddf:DEFDS_0628 hypothetical protein; PFAM: Membrane protein of unknown function; SPTR: Putative uncharacterized protein YP_004602984.1 PFAM: Membrane protein of unknown function; KEGG: cni:Calni_0841 hypothetical protein; SPTR: Putative uncharacterized protein YP_004602985.1 COGs: COG4517 conserved hypothetical protein; InterPro IPR014949; KEGG: ddf:DEFDS_0630 hypothetical protein; PFAM: Protein of unknown function DUF1820; SPTR: Putative uncharacterized protein YP_004602986.1 PFAM: Domain of unknown function (DUF1820); COGs: COG0795 permease; InterPro IPR005495; KEGG: ddf:DEFDS_0631 hypothetical protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Putative uncharacterized protein YP_004602987.1 PFAM: Predicted permease YjgP/YjgQ family; COGs: COG0795 permease; InterPro IPR005495; KEGG: dap:Dacet_1505 permease YjgP/YjgQ family protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ family protein YP_004602988.1 PFAM: Predicted permease YjgP/YjgQ family; COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; HAMAP: Isopropylmalate dehydrogenase; InterPro IPR001804:IPR004429; KEGG: ddf:DEFDS_0681 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: Isopropylmalate dehydrogenase YP_004602989.1 PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR001450:IPR004017; KEGG: cni:Calni_1714 hypothetical protein; PFAM: Protein of unknown function DUF162; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; SPTR: Putative uncharacterized protein YP_004602990.1 PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: ddf:DEFDS_1348 hypothetical protein; PFAM: Protein of unknown function DUF162; SPTR: Putative uncharacterized protein YP_004602991.1 PFAM: Uncharacterised ACR, YkgG family COG1556; COGs: COG4663 TRAP-type mannitol/chloroaromatic compound transport system periplasmic component; InterPro IPR018389; KEGG: cni:Calni_1350 extracellular solute-binding protein, family 7; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Extracellular solute-binding protein, family 7 YP_004602992.1 PFAM: Bacterial extracellular solute-binding protein, family 7; COGs: COG4665 TRAP-type mannitol/chloroaromatic compound transport system small permease component; InterPro IPR007387; KEGG: cni:Calni_1351 tripartite ATP-independent periplasmic transporter DctQ component; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Tripartite ATP-independent periplasmic transporter DctQ component YP_004602993.1 PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG4664 TRAP-type mannitol/chloroaromatic compound transport system large permease component; InterPro IPR010656:IPR004681; KEGG: cni:Calni_1352 trap dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit YP_004602994.1 PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: cni:Calni_1348 fad linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: FAD linked oxidase domain protein YP_004602995.1 PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: cni:Calni_1349 hypothetical protein; PFAM: Cysteine-rich region, CCG; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein YP_004602996.1 PFAM: Cysteine-rich domain; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: cni:Calni_1712 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; GntR, C-terminal; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family YP_004602997.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: sul:SYO3AOP1_0595 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004602998.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002880:IPR019752:IPR019456:IPR001450:IPR 011766:IPR011895; KEGG: ddf:DEFDS_0568 pyruvate:ferredoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase YP_004602999.1 PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: ddf:DEFDS_0569 acyl-CoA synthase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Acyl-CoA synthase YP_004603000.1 PFAM: AMP-binding enzyme; COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: dap:Dacet_1688 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SPTR: Nitrogen regulatory protein P-II YP_004603001.1 PFAM: Nitrogen regulatory protein P-II; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: ddf:DEFDS_1474 glutamine synthetase type I; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I YP_004603002.1 PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I YP_004603003.1 PFAM: CheD; manually curated YP_004603004.1 PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; NMT1/THI5 like; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR000160; KEGG: hha:Hhal_0365 response regulator receiver modulated diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted YP_004603005.1 PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001789:IPR013767:IPR003661:IPR003594:IPR 000014:IPR001610; KEGG: signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Putative uncharacterized protein; TIGRFAM: PAS YP_004603006.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; InterPro IPR012912; KEGG: xbo:XBJ1_3617 hypothetical protein; PFAM: Plasmid pRiA4b ORF-3-like; SPTR: Putative uncharacterized protein YP_004603007.1 PFAM: Plasmid pRiA4b ORF-3-like protein; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603008.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG2186 Transcriptional regulators; InterPro IPR000524; KEGG: dal:Dalk_0697 regulatory protein GntR HTH; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Regulatory protein GntR HTH YP_004603009.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG2303 Choline dehydrogenase and related flavoprotein; InterPro IPR000172:IPR007867:IPR011533; KEGG: drt:Dret_0130 choline dehydrogenase; PFAM: Glucose-methanol-choline oxidoreductase, N-terminal; Glucose-methanol-choline oxidoreductase, C-terminal; PRIAM: Choline dehydrogenase; SPTR: Choline dehydrogenase; TIGRFAM: Choline dehydrogenase YP_004603010.1 PFAM: GMC oxidoreductase; TIGRFAM: choline dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR011264; KEGG: drt:Dret_0129 betaine aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Betaine-aldehyde dehydrogenase; SPTR: Glycine betaine aldehyde dehydrogenase; TIGRFAM: Betaine aldehyde dehydrogenase YP_004603011.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: glycine betaine aldehyde dehydrogenase; COGs: COG2113 ABC-type proline/glycine betaine transport systems periplasmic components; InterPro IPR007210; KEGG: drt:Dret_0128 substrate-binding region of ABC-type glycine betaine transport system; PFAM: ABC-type glycine betaine transport system, substrate-binding region; SPTR: Substrate-binding region of ABC-type glycine betaine transport system YP_004603012.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system; TIGRFAM: choline ABC transporter, periplasmic binding protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR012840; KEGG: ddf:DEFDS_1634 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM; SPTR: Anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like YP_004603013.1 PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; KEGG: rsd:TGRD_582 putative ribonucleoside-triphosphate reductase; SPTR: Putative ribonucleoside-triphosphate reductase YP_004603014.1 COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic YP_004603015.1 PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR013196:IPR004143; KEGG: chy:CHY_2371 BirA bifunctional protein; SPTR: BirA bifunctional protein YP_004603016.1 PFAM: HTH domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: BirA biotin operon repressor domain; birA, biotin-[acetyl-CoA-carboxylase] ligase region; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603017.1 PFAM: Transposase DDE domain; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814:IPR005815; KEGG: amc:MADE_02212 adenosylmethionine--8-amino-7-oxononanoate transaminase; PFAM: Aminotransferase class-III; PRIAM: Adenosylmethionine--8-amino-7-oxononanoate transaminase; SPTR: Adenosylmethionine--8-amino-7-oxononanoate transaminase; TIGRFAM: Adenosylmethionine--8-amino-7-oxononanoate aminotransferase YP_004603018.1 PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; COGs: COG0132 Dethiobiotin synthetase; HAMAP: Dethiobiotin synthase; InterPro IPR004472; KEGG: pmm:PMM1471 putative dethiobiotin synthase; PRIAM: Dethiobiotin synthase; SPTR: Dethiobiotin synthetase; TIGRFAM: Dethiobiotin synthase YP_004603019.1 TIGRFAM: dethiobiotin synthase; COGs: COG0502 Biotin synthase; HAMAP: Biotin synthase; InterPro IPR007197:IPR010722:IPR006638:IPR002684; KEGG: dol:Dole_0682 biotin synthase; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; PRIAM: Biotin synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; TIGRFAM: Biotin synthase YP_004603020.1 PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: ddf:DEFDS_1301 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase, class I/II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: 8-amino-7-oxononanoate synthase YP_004603021.1 PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; KEGG: dsa:Desal_1448 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603022.1 InterPro IPR013216; KEGG: ddf:DEFDS_1303 biotin biosynthesis protein BioC; PFAM: Methyltransferase type 11; SPTR: Biotin biosynthesis protein BioC YP_004603023.1 PFAM: Methyltransferase domain; TIGRFAM: biotin biosynthesis protein BioC; COGs: COG1576 conserved hypothetical protein; HAMAP: Ribosomal RNA large subunit methyltransferase H; InterPro IPR003742; KEGG: cni:Calni_2051 hypothetical protein; PFAM: SPOUT methyltransferase, predicted; SPTR: Ribosomal RNA large subunit methyltransferase H YP_004603024.1 PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH; COGs: COG1734 DnaK suppressor protein; InterPro IPR000962; KEGG: dap:Dacet_2921 transcriptional regulator, TraR/DksA family; SPTR: Transcriptional regulator, TraR/DksA family YP_004603025.1 PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA; COGs: COG0696 Phosphoglyceromutase; HAMAP: Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; InterPro IPR011258:IPR006124:IPR005995; KEGG: ddf:DEFDS_1896 phosphoglycerate mutase; PFAM: BPG-independent PGAM, N-terminal; Metalloenzyme; PRIAM: Phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent YP_004603026.1 PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: cni:Calni_1596 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase YP_004603027.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: ddf:DEFDS_1893 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I YP_004603028.1 PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: cni:Calni_1593 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase YP_004603029.1 PFAM: Phosphoglycerate kinase; COGs: COG0060 Isoleucyl-tRNA synthetase; HAMAP: Isoleucyl-tRNA synthetase; InterPro IPR002300:IPR013155:IPR010663:IPR002301; KEGG: cni:Calni_1082 isoleucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; DNA glycosylase/AP lyase/isoleucyl tRNA synthetase, zinc finger domain; PRIAM: Isoleucine--tRNA ligase; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: Isoleucyl-tRNA synthetase, class Ia YP_004603030.1 PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase; COGs: COG0597 Lipoprotein signal peptidase; HAMAP: Peptidase A8, signal peptidase II; InterPro IPR001872; KEGG: ddf:DEFDS_1186 lipoprotein signal peptidase II; PFAM: Peptidase A8, signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: Peptidase A8, signal peptidase II YP_004603031.1 PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: Bifunctional purine biosynthesis protein purH; InterPro IPR011607:IPR013982:IPR002695; KEGG: ddf:DEFDS_1187 bifunctional purine biosynthesis protein PurH; PFAM: AICARFT/IMPCHase bienzyme, formylation region; MGS-like; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, formylation region; SPTR: Bifunctional purine biosynthesis protein purH; TIGRFAM: AICARFT/IMPCHase bienzyme YP_004603032.1 PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR020562:IPR020561:IPR020560:IPR000115; KEGG: ddf:DEFDS_1188 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase YP_004603033.1 PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: dap:Dacet_1774 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: Phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_004603034.1 PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070:IPR004388; KEGG: dap:Dacet_1775 SUA5/YciO/YrdC domain protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: SUA5/yciO/yrdC domain protein; TIGRFAM: Sua5/YciO/YrdC/YwlC YP_004603035.1 PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; KEGG: caa:Caka_2024 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603036.1 KEGG: ddf:DEFDS_0308 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603037.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: ddf:DEFDS_0765 acetylornithine deacetylase; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Acetylornithine deacetylase YP_004603038.1 PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: N-acetyl-ornithine/N-acetyl-lysine deacetylase; COGs: COG0456 Acetyltransferase; InterPro IPR000182; KEGG: ddf:DEFDS_0766 acetyltransferase GNAT family; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, GNAT family YP_004603039.1 PFAM: Acetyltransferase (GNAT) family YP_004603040.1 PFAM: Sel1 repeat; KEGG: nhl:Nhal_1311 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603041.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: dap:Dacet_2762 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_004603042.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: str:Sterm_2402 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_004603043.1 PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase; manually curated YP_004603044.1 PFAM: Receptor family ligand binding region; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: dap:Dacet_0893 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator YP_004603045.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: dap:Dacet_0894 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator YP_004603046.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_0346 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004603047.1 PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dap:Dacet_0896 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004603048.1 PFAM: ABC transporter; manually curated YP_004603049.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: ddf:DEFDS_0574 phosphoesterase; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Phosphoesterase YP_004603050.1 PFAM: DHH family; DHHA1 domain; KEGG: dap:Dacet_1862 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated YP_004603051.1 COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR005653:IPR007543; KEGG: cni:Calni_0052 OstA family protein; PFAM: OstA-like protein; Organic solvent tolerance protein; SPTR: OstA family protein; manually curated YP_004603052.1 PFAM: OstA-like protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR001645; KEGG: cni:Calni_0051 FolC bifunctional protein; PFAM: Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase YP_004603053.1 PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; COGs: COG0777 Acetyl-CoA carboxylase beta subunit; HAMAP: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; InterPro IPR000022:IPR000438; KEGG: ddf:DEFDS_0579 acetyl-CoA carboxylase carboxyl transferase subunit beta; PFAM: Carboxyl transferase; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; TIGRFAM: Acetyl-CoA carboxylase carboxyl transferase, beta subunit YP_004603054.1 PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit YP_004603055.1 This gene is disrupted by insertion of repetitive element; manually curated YP_004603056.1 KEGG: ddf:DEFDS_1470 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603057.1 PFAM: Bacterial virulence factor lipase N-terminal; InterPro IPR000182:IPR012772; KEGG: bha:BH0920 diaminobutyric acid acetyltransferase; PFAM: GCN5-related N-acetyltransferase; PRIAM: Diaminobutyrate acetyltransferase; SPTR: L-2,4-diaminobutyric acid acetyl transferase; TIGRFAM: L-2,4-diaminobutyric acid acetyltransferase YP_004603058.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: diaminobutyrate acetyltransferase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814:IPR004637:IPR012773; KEGG: diaminobutyrate/2-oxoglutarate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Diaminobutyrate--2-oxoglutarate transaminase; SPTR: Diaminobutyrate/2-oxoglutarate aminotransferase; TIGRFAM: Diaminobutyrate--2-oxoglutarate aminotransferase; Diaminobutyrate-2-oxoglutarate transaminase YP_004603059.1 PFAM: Aminotransferase class-III; TIGRFAM: 2,4-diaminobutyrate 4-transaminases; diaminobutyrate--2-oxoglutarate aminotransferase; HAMAP: L-ectoine synthase; InterPro IPR010462; KEGG: dal:Dalk_1172 L-ectoine synthase; PFAM: Ectoine synthase; PRIAM: Ectoine synthase; SPTR: L-ectoine synthase YP_004603060.1 PFAM: Ectoine synthase; COGs: COG2524 transcriptional regulator protein; InterPro IPR000644; KEGG: ddf:DEFDS_0494 acetoin utilization protein AcuB; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Acetoin utilization protein AcuB YP_004603061.1 PFAM: CBS domain; COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: sul:SYO3AOP1_1339 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Transposase IS116/IS110/IS902 family protein YP_004603062.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107; KEGG: dap:Dacet_1530 integrase family protein; PFAM: Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase xerC 2 YP_004603063.1 PFAM: Phage integrase, N-terminal SAM-like domain; KEGG: fpl:Ferp_2539 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603064.1 KEGG: mfs:MFS40622_1358 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603065.1 manually curated YP_004603066.1 PFAM: IstB-like ATP binding protein; manually curated YP_004603067.1 KEGG: sun:SUN_1976 transposase; SPTR: Transposase, IS4 family protein YP_004603068.1 KEGG: pop:POPTR_597343 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603070.1 COGs: COG3031 Type II secretory pathway component PulC; KEGG: dap:Dacet_0489 type II secretory pathway component PulC-like protein; SPTR: Type II secretory pathway component PulC-like protein YP_004603071.1 TIGRFAM: general secretion pathway protein C; COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR005644:IPR004846:IPR013356; KEGG: ddf:DEFDS_1308 general secretion pathway protein D; PFAM: Type II/III secretion system; NolW-like; SPTR: General secretion pathway protein D; TIGRFAM: Type II secretion system gspD YP_004603072.1 PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein; TIGRFAM: general secretion pathway protein D; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482:IPR003593; KEGG: ddf:DEFDS_1307 general secretion pathway protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: General secretion pathway protein E YP_004603073.1 PFAM: Type II/IV secretion system protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: dap:Dacet_0492 type II secretion system F domain protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system F domain protein YP_004603074.1 PFAM: Bacterial type II secretion system protein F domain; COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: sul:SYO3AOP1_1339 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Transposase IS116/IS110/IS902 family protein YP_004603075.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: pmx:PERMA_1157 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged helix family YP_004603076.1 PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; InterPro IPR003594; KEGG: cni:Calni_1201 hypothetical protein; PFAM: ATP-binding region, ATPase-like; SPTR: Putative uncharacterized protein YP_004603078.1 COGs: COG3419 Tfp pilus assembly protein tip-associated adhesin PilY1; KEGG: sul:SYO3AOP1_1017 Tfp pilus assembly protein tip-associated adhesin PilY1-like protein; SPTR: Tfp pilus assembly protein tip-associated adhesin PilY1-like protein YP_004603079.1 InterPro IPR012902 YP_004603080.1 PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; InterPro IPR012902 YP_004603081.1 PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; InterPro IPR012902; KEGG: tye:THEYE_A0596 prepilin-type N-terminal cleavage/methylation domain protein; SPTR: Prepilin-type N-terminal cleavage/methylation domain protein YP_004603082.1 TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; KEGG: geo:Geob_3073 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603084.1 COGs: COG1484 DNA replication protein; InterPro IPR002611:IPR003593; KEGG: sfu:Sfum_2832 IstB ATP binding domain-containing protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core; SPTR: IstB domain protein ATP-binding protein YP_004603085.1 PFAM: IstB-like ATP binding protein; COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: mac:MA2579 transposase; PFAM: Integrase, catalytic core; SPTR: Transposase, IS21 YP_004603086.1 PFAM: Integrase core domain; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603087.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); InterPro IPR001387; KEGG: glo:Glov_3687 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family YP_004603088.1 PFAM: Helix-turn-helix; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: hya:HY04AAS1_1299 HipA domain protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: HipA domain protein YP_004603089.1 PFAM: HipA-like N-terminal domain; HipA-like C-terminal domain; TIGRFAM: HipA N-terminal domain; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: dap:Dacet_1179 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family YP_004603090.1 PFAM: MarR family; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: ddf:DEFDS_1074 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+); PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP+) YP_004603091.1 PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase; COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: cni:Calni_0968 integrase family protein; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase xerC 1 YP_004603092.1 PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR000644:IPR002646; KEGG: cni:Calni_0967 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; Cystathionine beta-synthase, core; Phosphoesterase, RecJ-like; SMART: Cystathionine beta-synthase, core; SPTR: Polynucleotide adenylyltransferase region YP_004603093.1 PFAM: DHH family; CBS domain; Poly A polymerase head domain; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR018111:IPR003714; KEGG: ddf:DEFDS_1078 phosphate starvation-induced protein PhoH; PFAM: PhoH-like protein; K Homology, type 1, subgroup; SPTR: Phosphate starvation-induced protein PhoH YP_004603094.1 PFAM: KH domain; PhoH-like protein; COGs: COG0319 metal-dependent hydrolase; HAMAP: Uncharacterised protein family UPF0054; InterPro IPR002036; KEGG: ddf:DEFDS_1079 hypothetical protein; PFAM: Uncharacterised protein family UPF0054; SPTR: Probable rRNA maturation factor; TIGRFAM: Uncharacterised protein family UPF0054 YP_004603095.1 PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829:IPR000326; KEGG: cni:Calni_0964 diacylglycerol kinase; PFAM: Diacylglycerol kinase, prokaryotic; Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: Diacylglycerol kinase YP_004603096.1 PFAM: Prokaryotic diacylglycerol kinase; PAP2 superfamily; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: ddf:DEFDS_1081 magnesium/cobalt efflux protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core; SPTR: Magnesium/cobalt efflux protein YP_004603097.1 PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain; COGs: COG1159 GTPase; HAMAP: GTP-binding protein Era; InterPro IPR002917:IPR004044:IPR005662:IPR005225; KEGG: ddf:DEFDS_1082 GTP-binding protein Era; PFAM: GTP-binding protein, HSR1-related; K Homology, type 2; SPTR: GTP-binding protein Era; TIGRFAM: GTP-binding protein Era; Small GTP-binding protein YP_004603098.1 PFAM: GTPase of unknown function; KH domain; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain; KEGG: ddf:DEFDS_1084 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603099.1 PFAM: Recombination protein O N terminal; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: ddf:DEFDS_1464 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603100.1 PFAM: Metallo-beta-lactamase superfamily; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603101.1 PFAM: Transposase domain (DUF772); manually curated YP_004603102.1 PFAM: Putative ammonia monooxygenase; TIGRFAM: membrane protein AbrB duplication; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: gym:GYMC10_0864 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR, N-terminal; Transcriptional regulator IclR, C-terminal; SMART: Transcriptional regulator IclR, N-terminal; SPTR: Transcriptional regulator, IclR family YP_004603103.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterPro IPR013767:IPR003594:IPR000014; KEGG: bld:BLi01245 hypothetical protein; PFAM: ATP-binding region, ATPase-like; PAS fold; SMART: ATP-binding region, ATPase-like; PAS; SPTR: Putative uncharacterized protein YP_004603104.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG4565 Response regulator of citrate/malate metabolism; InterPro IPR001789; KEGG: dap:Dacet_1391 response regulator receiver and unknown domain protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Putative uncharacterized protein YP_004603105.1 PFAM: Response regulator receiver domain; Transcriptional regulator; COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: ppr:PBPRA2754 putative tricarboxylic transport TctC; SPTR: Putative tricarboxylic transport TctC YP_004603106.1 PFAM: Tripartite tricarboxylate transporter family receptor; KEGG: tricarboxylate transport protein TctB; SPTR: Putative uncharacterized protein YP_004603107.1 COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: abu:Abu_0100 putative tricarboxylic transport protein TctA; PFAM: Protein of unknown function DUF112, transmembrane; SPTR: Putative tricarboxylic transport TctA YP_004603108.1 PFAM: Tripartite tricarboxylate transporter TctA family; COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR005793; KEGG: dap:Dacet_2496 formyl transferase domain protein; PFAM: Formyl transferase, C-terminal; SPTR: Formyl transferase domain protein YP_004603109.1 PFAM: Formyl transferase; Formyl transferase, C-terminal domain; COGs: COG4907 membrane protein; InterPro IPR018702; KEGG: ddf:DEFDS_1130 hypothetical protein; PFAM: Protein of unknown function DUF2207, membrane; SPTR: Putative uncharacterized protein YP_004603110.1 PFAM: Predicted membrane protein (DUF2207); COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: ddf:DEFDS_1131 hypothetical protein; PFAM: LemA; SPTR: Putative uncharacterized protein YP_004603111.1 PFAM: LemA family; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: ddf:DEFDS_1132 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603112.1 PFAM: Metallo-beta-lactamase superfamily; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: tba:TERMP_00347 2-oxoglutarate oxidoreductase subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoacid:ferredoxin oxidoreductase, subunit alpha; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit YP_004603113.1 PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766:IPR011896; KEGG: pfu:PF0753 2-oxoacid ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-keto acid:ferredoxin oxidoreductase subunit beta; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate YP_004603114.1 PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dap:Dacet_1247 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase YP_004603115.1 PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: cni:Calni_0864 cbs domain containing membrane protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing membrane protein YP_004603116.1 PFAM: CBS domain; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: ddf:DEFDS_0852 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein YP_004603117.1 PFAM: Uncharacterised ArCR, COG2043; COGs: COG1190 Lysyl-tRNA synthetase (class II); HAMAP: Lysyl-tRNA synthetase; InterPro IPR004365:IPR004364:IPR002313; KEGG: ddf:DEFDS_1155 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class II YP_004603118.1 PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cni:Calni_0361 phosphodiesterase, mj0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025 YP_004603119.1 TIGRFAM: phosphoesterase, MJ0936 family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: cni:Calni_0362 rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl YP_004603120.1 PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; COGs: COG1792 Cell shape-determining protein; InterPro IPR007221:IPR005223; KEGG: ddf:DEFDS_1159 cell shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Cell shape-determining protein MreC; TIGRFAM: Rod shape-determining protein MreC, subtype YP_004603121.1 PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; KEGG: dap:Dacet_1266 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603122.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: ddf:DEFDS_1161 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; TIGRFAM: Penicillin-binding protein 2 YP_004603123.1 PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR011923; KEGG: dap:Dacet_1268 rod shape-determining protein RodA; PFAM: Cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: Rod shape-determining protein RodA YP_004603124.1 PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR018768:IPR006638; KEGG: ddf:DEFDS_1163 Fe-S oxidoreductases family protein; PFAM: Radical SAM; Protein of unknown function DUF2344; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductases family protein YP_004603125.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2344); Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein; radical SAM-linked protein; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ddf:DEFDS_1164 ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family YP_004603126.1 PFAM: Ferric uptake regulator family; InterPro IPR014127; KEGG: cni:Calni_0369 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02757 YP_004603127.1 PFAM: Protein of unknown function (DUF2400); TIGRFAM: TIGR02757 family protein; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: ddf:DEFDS_1167 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin YP_004603128.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin; InterPro IPR013429; KEGG: ddf:DEFDS_1168 hypothetical protein; PFAM: Regulatory protein, FmdB, putative; SPTR: Putative uncharacterized protein; TIGRFAM: Regulatory protein, FmdB, putative YP_004603129.1 PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dap:Dacet_1449 histone family protein DNA-binding protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein YP_004603130.1 PFAM: Bacterial DNA-binding protein; TIGRFAM: integration host factor, beta subunit; COGs: COG0728 membrane protein putative virulence factor; InterPro IPR004268; KEGG: cni:Calni_1205 integral membrane protein MviN; PFAM: Flagellin assembly, membrane protein MviN; SPTR: Integral membrane protein MviN; TIGRFAM: Flagellin assembly, membrane protein MviN YP_004603131.1 PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN; COGs: COG1490 D-Tyr-tRNAtyr deacylase; HAMAP: D-tyrosyl-tRNA(Tyr) deacylase; InterPro IPR003732; KEGG: ddf:DEFDS_1421 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_004603132.1 PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: ddf:DEFDS_1420 metallo-beta-lactamase family protein; SPTR: Metallo-beta-lactamase family protein YP_004603133.1 PFAM: Metallo-beta-lactamase superfamily; COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: ddf:DEFDS_0971 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase YP_004603134.1 PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; COGs: COG1515 Deoxyinosine 3'endonuclease (endonuclease V); HAMAP: Endonuclease V; InterPro IPR007581; KEGG: ddf:DEFDS_0855 deoxyribonuclease V; PFAM: Endonuclease V; PRIAM: Deoxyribonuclease V; SPTR: Endonuclease V YP_004603135.1 PFAM: Endonuclease V; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: ddf:DEFDS_1259 patatin-like phospholipase family protein; PFAM: Patatin; SPTR: Patatin-like phospholipase family protein YP_004603136.1 PFAM: Patatin-like phospholipase; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: ddf:DEFDS_1258 hypothetical protein; PFAM: BioY protein; SPTR: Putative uncharacterized protein YP_004603137.1 PFAM: BioY family; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: ddf:DEFDS_1369 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase YP_004603138.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: ddf:DEFDS_0995 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein YP_004603139.1 PFAM: Radical SAM superfamily; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: cni:Calni_1099 hypothetical protein; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: Putative uncharacterized protein YP_004603140.1 PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: ddf:DEFDS_0997 hypothetical protein; PFAM: Alanine racemase, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: pyridoxal phosphate-dependent enzyme, YBL036C type YP_004603141.1 PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family; InterPro IPR003425; KEGG: ddf:DEFDS_0998 hypothetical protein; PFAM: Protein of unknown function YGGT; SPTR: Putative uncharacterized protein YP_004603142.1 PFAM: YGGT family; COGs: COG4956 Integral membrane protein (PIN domain superfamily); InterPro IPR002716:IPR002792:IPR006596; KEGG: ddf:DEFDS_1000 hypothetical protein; PFAM: PilT protein, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: Nucleotide binding protein, PINc; SPTR: Putative uncharacterized protein YP_004603143.1 PFAM: TRAM domain; PIN domain; COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; HAMAP: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; InterPro IPR001228; KEGG: ddf:DEFDS_1001 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; PRIAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_004603144.1 PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; manually curated YP_004603145.1 PFAM: 2-nitropropane dioxygenase; KEGG: sun:SUN_1976 transposase; SPTR: Transposase, IS4 family protein YP_004603146.1 COGs: COG5421 Transposase; InterPro IPR002559; KEGG: dal:Dalk_2552 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603147.1 PFAM: Transposase DDE domain; COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004603148.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR008030; KEGG: dap:Dacet_2046 NmrA family protein; SPTR: NmrA family protein YP_004603149.1 PFAM: Protein of unknown function (DUF2867); NmrA-like family; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: has:Halsa_0198 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted YP_004603150.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5012 cobalamin binding protein; InterPro IPR006158; KEGG: dal:Dalk_1842 cobalamin B12-binding; PFAM: Cobalamin (vitamin B12)-binding; SPTR: Cobalamin B12-binding YP_004603151.1 PFAM: B12 binding domain; KEGG: dal:Dalk_1840 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603152.1 COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: kcr:Kcr_0220 arsenite-transporting ATPase; PFAM: ATPase, anion-transporting; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenite-transporting ATPase YP_004603153.1 PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA; KEGG: cni:Calni_0016 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603154.1 COGs: COG0225 Peptide methionine sulfoxide reductase; HAMAP: Peptide methionine sulphoxide reductase MsrA; InterPro IPR002569; KEGG: sfr:Sfri_1402 peptide methionine sulfoxide reductase; PFAM: Peptide methionine sulphoxide reductase MsrA; PRIAM: Peptide-methionine (S)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrA 1; TIGRFAM: Peptide methionine sulphoxide reductase MsrA YP_004603155.1 PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603156.1 PFAM: Transposase domain (DUF772); COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: hor:Hore_20910 sodium:neurotransmitter symporter; PFAM: Sodium:neurotransmitter symporter; SPTR: Transporter YP_004603157.1 PFAM: Sodium:neurotransmitter symporter family; KEGG: cni:Calni_0609 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603158.1 PFAM: Uncharacterized protein conserved in bacteria C-term(DUF2220); COGs: COG3096 conserved hypothetical protein involved in chromosome partitioning; KEGG: cni:Calni_0610 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603159.1 PFAM: MukB N-terminal; KEGG: cni:Calni_0611 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603160.1 KEGG: cni:Calni_0612 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603161.1 manually curated YP_004603162.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: dat:HRM2_39560 HTH-type transcriptional regulator (MArR family protein); PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: HTH-type transcriptional regulator (MArR family protein) YP_004603163.1 PFAM: MarR family; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099; KEGG: gsu:GSU2588 alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Dihydrolipoyl dehydrogenase YP_004603164.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG4108 Peptide chain release factor RF-3; InterPro IPR000795:IPR004161:IPR004548:IPR005225; KEGG: gvi:glr3159 peptide chain release factor 3; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Strongly similar to translation releasing factor RF-3; TIGRFAM: Peptide chain release factor 3; Small GTP-binding protein YP_004603165.1 PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; peptide chain release factor 3; KEGG: tau:Tola_1477 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603166.1 COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: dsa:Desal_3552 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1 YP_004603167.1 PFAM: Bacterial extracellular solute-binding protein; COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: dsa:Desal_3553 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004603168.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: dsa:Desal_3554 ABC transporter related; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related YP_004603169.1 PFAM: ABC transporter; TOBE domain; manually curated YP_004603170.1 PFAM: Aminotransferase class IV; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: ddf:DEFDS_1304 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase component I YP_004603171.1 PFAM: chorismate binding enzyme; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: oih:OB0691 betaine-homocysteine methyltransferase; PFAM: Homocysteine S-methyltransferase; PRIAM: Betaine--homocysteine S-methyltransferase; SPTR: Betaine-homocysteine methyltransferase YP_004603172.1 PFAM: Homocysteine S-methyltransferase; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603173.1 PFAM: Transposase DDE domain; InterPro IPR011579:IPR004256; KEGG: mtt:Ftrac_2201 duf234 dexx-box atpase; SPTR: DUF234 DEXX-box ATPase YP_004603174.1 PFAM: Archaeal ATPase; Archaea bacterial proteins of unknown function; InterPro IPR011462; KEGG: caa:Caka_2052 protein of unknown function DUF1568; SPTR: Putative uncharacterized protein YP_004603175.1 PFAM: Transposase IS200 like; InterPro IPR004919:IPR018651; KEGG: hmo:HM1_2923 hypothetical protein; PFAM: Protein of unknown function DUF262; Protein of unknown function DUF2081; SPTR: Putative uncharacterized protein YP_004603176.1 PFAM: Uncharacterized conserved protein (DUF2081); Protein of unknown function DUF262; Protein of unknown function (DUF1524); COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR003799; KEGG: tpt:Tpet_1081 CRISPR-associated Cas2 family protein; SPTR: CRISPR-associated protein, Cas2 family; TIGRFAM: Protein of unknown function DUF196 YP_004603177.1 PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2; COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729:IPR019858; KEGG: brm:Bmur_1230 CRISPR-associated protein Cas1; PFAM: CRISPR-associated protein Cas1; SPTR: CRISPR-associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1, HMARI/TNEAP subtype; CRISPR-associated protein Cas1 YP_004603178.1 PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP; CRISPR-associated endonuclease Cas1; COGs: COG1468 RecB family exonuclease; InterPro IPR013343; KEGG: cli:Clim_0447 CRISPR-associated protein Cas4; PFAM: CRISPR-associated protein Cas4; SPTR: CRISPR-associated protein Cas4; TIGRFAM: CRISPR-associated protein Cas4 YP_004603179.1 PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4; COGs: COG1203 helicase; InterPro IPR014001:IPR001650:IPR006483:IPR006474; KEGG: tye:THEYE_A2039 CRISPR-associated helicase Cas3; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: CRISPR-associated helicase Cas3; TIGRFAM: Helicase Cas3, CRISPR-associated, core; CRISPR-associated HD domain YP_004603180.1 PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD; InterPro IPR007552:IPR013422; KEGG: tye:THEYE_A2040 CRISPR-associated protein Cas5; SPTR: CRISPR-associated protein Cas5; TIGRFAM: CRISPR-associated protein Cas5 YP_004603181.1 PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR010154:IPR013414; KEGG: tye:THEYE_A2041 CRISPR-associated regulatory protein, DevR family; SPTR: CRISPR-associated regulatory protein, DevR family; TIGRFAM: CRISPR-associated regulatory DevR; CRISPR-associated negative autoregulator YP_004603182.1 PFAM: CRISPR-associated negative autoregulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP; InterPro IPR010180; KEGG: tye:THEYE_A2042 CRISPR-associated CXXC_CXXC protein Cst1; SPTR: CRISPR-associated CXXC_CXXC protein Cst1; TIGRFAM: CRISPR-associated protein, CXXC-CXXC YP_004603183.1 PFAM: CRISPR-associated protein (Cas_CXXC_CXXC); TIGRFAM: CRISPR-associated protein Cas8a1/Cst1, subtype I-B/TNEAP; COGs: COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR002743:IPR010156; KEGG: str:Sterm_1593 CRISPR-associated protein Cas6; PFAM: Protein of unknown function DUF57; SPTR: CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein, Cas6 YP_004603184.1 PFAM: CRISPR associated protein Cas6; TIGRFAM: CRISPR-associated endoribonuclease Cas6; COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: gur:Gura_1947 hydrogenase maturation protease; PFAM: Peptidase A31, hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogen uptake protein YP_004603185.1 PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease; COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: gur:Gura_1946 nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Nickel-dependent hydrogenase, large subunit YP_004603186.1 PFAM: Nickel-dependent hydrogenase; COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: glo:Glov_0146 putative hydrogenase 2 b cytochrome subunit; PFAM: Polysulphide reductase, NrfD; SPTR: Polysulphide reductase NrfD YP_004603187.1 PFAM: Polysulphide reductase, NrfD; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450:IPR006311; KEGG: gbm:Gbem_3138 hydrogenase 2 protein HybA; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Periplasmically oriented, membrane-bound [NiFe]-hydrogenase iron-sulfur cluster-binding subunit YP_004603188.1 COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137:IPR001821:IPR006311; KEGG: dap:Dacet_1223 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Hydrogenase (NiFe) small subunit HydA; TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence YP_004603189.1 PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA); KEGG: dap:Dacet_1058 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603190.1 PFAM: ABC transporter substrate binding protein; Uncharacterized protein conserved in bacteria (DUF2325); COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR007831; KEGG: cni:Calni_1450 general secretory system II protein e domain protein; PFAM: General secretory system II, protein E, N-terminal; SPTR: General secretory system II protein E domain protein YP_004603191.1 PFAM: GSPII_E N-terminal domain; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR011545:IPR014001:IPR006555; KEGG: cni:Calni_1449 dead/deah box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; SMART: Helicase, ATP-dependent, c2 type; DEAD-like helicase, N-terminal; SPTR: DEAD/DEAH box helicase domain protein YP_004603192.1 PFAM: DEAD_2; DEAD/DEAH box helicase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: dap:Dacet_1293 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase YP_004603193.1 PFAM: Phosphoglucose isomerase; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; HAMAP: tRNA(Ile)-lysidine synthase; InterPro IPR011063:IPR012795:IPR012796; KEGG: ddf:DEFDS_1027 cell cycle protein MesJ; PFAM: PP-loop; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: Lysidine-tRNA(Ile) synthetase, N-terminal; Lysidine-tRNA(Ile) synthetase, C-terminal YP_004603194.1 PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: cni:Calni_1446 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase YP_004603195.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; COGs: COG0465 ATP-dependent Zn protease; InterProIPR011546:IPR003959:IPR000642:IPR003593:IPR 005936; KEGG: ddf:DEFDS_1029 cell division protein FtsH; PFAM: Peptidase M41; ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein FtsH; TIGRFAM: Peptidase M41, FtsH YP_004603196.1 PFAM: FtsH Extracellular; Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: cni:Calni_1444 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase YP_004603197.1 PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase; COGs: COG1624 conserved hypothetical protein; InterPro IPR003390:IPR014046; KEGG: ddf:DEFDS_1031 hypothetical protein; PFAM: DNA integrity scanning protein, DisA, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00159 YP_004603198.1 PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: TIGR00159 family protein; InterPro IPR012505; KEGG: ddf:DEFDS_1032 hypothetical protein; PFAM: YbbR-like; SPTR: Putative uncharacterized protein YP_004603199.1 PFAM: YbbR-like protein; COGs: COG1109 Phosphomannomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 006352; KEGG: ddf:DEFDS_1033 phosphoglucosamine mutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphoglucosamine mutase; TIGRFAM: Phosphoglucosamine mutase YP_004603200.1 PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase; COGs: COG0854 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ; InterPro IPR004569; KEGG: ddf:DEFDS_1034 pyridoxine 5-phosphate synthase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Pyridoxine 5'-phosphate synthase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ YP_004603201.1 PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; TIGRFAM: pyridoxine 5'-phosphate synthase; COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); HAMAP: Holo-[acyl-carrier-protein] synthase; InterPro IPR008278:IPR002582:IPR004568; KEGG: cni:Calni_1439 holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: Phosphopantethiene-protein transferase; Holo-[acyl carrier protein] synthase YP_004603202.1 PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase; COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; HAMAP: 3-deoxy-D-manno-octulosonate cytidylyltransferase; InterPro IPR004528:IPR003329; KEGG: ddf:DEFDS_1036 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: Acylneuraminate cytidylyltransferase; PRIAM: 3-deoxy-manno-octulosonate cytidylyltransferase; SPTR: 3-deoxy-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase YP_004603203.1 PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; COGs: COG0504 CTP synthase (UTP-ammonia lyase); HAMAP: CTP synthase; InterPro IPR004468:IPR017456:IPR000991; KEGG: ddf:DEFDS_1037 CTP synthase; PFAM: CTP synthase, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase YP_004603204.1 PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218:IPR006269; KEGG: ddf:DEFDS_1038 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-8-phosphooctulonate synthase; SPTR: 3-deoxy-8-phosphooctulonate synthase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase YP_004603205.1 PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347:IPR000644:IPR004800; KEGG: ddf:DEFDS_1039 arabinose-5-phosphate isomerase; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; PRIAM: Arabinose-5-phosphate isomerase; SMART: Cystathionine beta-synthase, core; SPTR: Arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ YP_004603206.1 PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834:IPR010023:IPR006549; KEGG: ddf:DEFDS_1040 3-deoxy-manno-octulosonate-8-phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: 3-deoxy-manno-octulosonate-8-phosphatase; SPTR: 3-deoxy-manno-octulosonate-8-phosphatase; TIGRFAM: Phosphatase KdsC; HAD-superfamily hydrolase, subfamily IIIA YP_004603207.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; InterPro IPR010664; KEGG: ddf:DEFDS_1041 hypothetical protein; PFAM: Protein of unknown function DUF1239; SPTR: Putative uncharacterized protein YP_004603208.1 PFAM: Protein of unknown function (DUF1239); COGs: COG1934 conserved hypothetical protein; InterPro IPR005653; KEGG: cni:Calni_1432 OstA family protein; PFAM: OstA-like protein; SPTR: OstA family protein YP_004603209.1 PFAM: OstA-like protein; TIGRFAM: lipopolysaccharide transport periplasmic protein LptA; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dap:Dacet_1308 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004603210.1 PFAM: ABC transporter; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: ddf:DEFDS_1044 DNA-directed RNA polymerase sigma 54 factor; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; RNA polymerase sigma factor 54; SPTR: DNA-directed RNA polymerase sigma 54 factor; TIGRFAM: RNA polymerase sigma factor 54 YP_004603211.1 PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor; COGs: COG1544 Ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: ddf:DEFDS_1045 sigma 54 modulation protein/ribosomal protein S30EA; PFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; SPTR: Sigma 54 modulation protein/ribosomal protein S30EA; TIGRFAM: Ribosomal protein S30Ae/sigma 54 modulation protein YP_004603212.1 PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: ddf:DEFDS_1046 PTS system fructose-specific transporter subunit IIA; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: PTS system, fructose-specific enzyme II, A component YP_004603213.1 PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component; COGs: COG1493 Serine kinase of the HPr protein regulates carbohydrate metabolism; HAMAP: HPr kinase/phosphorylase; InterPro IPR011126:IPR011104; KEGG: cni:Calni_1427 hpr(ser) kinase/phosphatase; PFAM: Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal; Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal; SPTR: HPr kinase/phosphorylase YP_004603214.1 PFAM: HPr Serine kinase N terminus; HPr Serine kinase C-terminal domain; TIGRFAM: Hpr(Ser) kinase/phosphatase; COGs: COG1660 P-loop-containing kinase; HAMAP: ATPase, P-loop-containing; InterPro IPR005337; KEGG: cni:Calni_1426 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein Calni_1426 YP_004603215.1 PFAM: P-loop ATPase protein family; COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: cni:Calni_1425 pts system fructose subfamily IIA component; PFAM: Phosphotransferase system, fructose subfamily IIA component; SPTR: PTS system fructose subfamily IIA component YP_004603216.1 PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component; COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: ddf:DEFDS_1050 PTS system fructose-specific transporter subunit IIB; PFAM: Phosphotransferase system, sorbose subfamily IIB component; SPTR: PTS system, fructose-specific enzyme II, B component YP_004603217.1 PFAM: PTS system sorbose subfamily IIB component; KEGG: ddf:DEFDS_1051 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603218.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: ddf:DEFDS_1052 hypothetical protein; PFAM: Phosphotransferase system, mannose/fructose/sorbose family IID component; SPTR: Putative uncharacterized protein YP_004603219.1 PFAM: PTS system mannose/fructose/sorbose family IID component; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: cni:Calni_1421 phosphotransferase system, phosphocarrier protein hpr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein YP_004603220.1 PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR008731:IPR008279:IPR000121:IPR006318; KEGG: ddf:DEFDS_1054 PTS system transporter enzyme I; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile region; PRIAM: Phosphoenolpyruvate--protein phosphotransferase; SPTR: PTS system, enzyme I, phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase YP_004603221.1 PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; KEGG: ddf:DEFDS_2164 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603222.1 PFAM: Predicted permease; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sfu:Sfum_0231 PAS/PAC sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: PAS/PAC sensor hybrid histidine kinase YP_004603223.1 PFAM: Response regulator receiver domain YP_004603224.1 PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: ddf:DEFDS_1484 hypothetical protein; PFAM: Protein of unknown function DUF164; SPTR: Putative uncharacterized protein YP_004603225.1 PFAM: Putative zinc ribbon domain; COGs: COG0328 Ribonuclease HI; InterPro IPR002156; KEGG: ddf:DEFDS_1483 ribonuclease HI; PFAM: Ribonuclease H; SPTR: Ribonuclease HI YP_004603226.1 PFAM: RNase H; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cbi:CLJ_B1218 zinc transporter, ZIP family; PFAM: Zinc/iron permease; SPTR: Zinc transporter, ZIP family YP_004603227.1 PFAM: ZIP Zinc transporter; KEGG: ddf:DEFDS_1480 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603228.1 COGs: COG0313 methyltransferase; HAMAP: Ribosomal RNA small subunit methyltransferase I; InterPro IPR000878:IPR008189; KEGG: ddf:DEFDS_0501 tetrapyrrole methylase family protein; PFAM: Tetrapyrrole methylase; SPTR: Ribosomal RNA small subunit methyltransferase I; TIGRFAM: Uncharacterised protein family UPF0011 YP_004603229.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family; KEGG: ddf:DEFDS_0502 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603230.1 PFAM: Protein of unknown function (DUF2914); COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: ddf:DEFDS_0503 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase YP_004603231.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; KEGG: cni:Calni_1309 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603232.1 COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638:IPR004393; KEGG: ddf:DEFDS_0506 nicotinate-nucleotide pyrophosphorylase carboxylating; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide pyrophosphorylase, carboxylating; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase YP_004603233.1 PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; COGs: COG0525 Valyl-tRNA synthetase; HAMAP: Valyl-tRNA synthetase; InterPro IPR002300:IPR013155:IPR019499:IPR002303; KEGG: ddf:DEFDS_0507 valyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA binding arm; PRIAM: Valine--tRNA ligase; SPTR: Valyl-tRNA synthetase; TIGRFAM: Valyl-tRNA synthetase, class Ia YP_004603234.1 PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase; KEGG: cni:Calni_1313 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603235.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: ddf:DEFDS_0509 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria YP_004603236.1 PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: ddf:DEFDS_0510 hypothetical protein; PFAM: YjeF-related protein, N-terminal; Uncharacterised protein family, carbohydrate kinase-related; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family, carbohydrate kinase-related; YjeF-related protein, N-terminal YP_004603237.1 PFAM: Carbohydrate kinase; YjeF-related protein N-terminus; TIGRFAM: yjeF C-terminal region, hydroxyethylthiazole kinase-related; yjeF N-terminal region; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611:IPR011913; KEGG: cni:Calni_1316 rfae bifunctional protein; PFAM: Carbohydrate/purine kinase; SPTR: RfaE bifunctional protein; TIGRFAM: RfaE bifunctional protein, domain I YP_004603238.1 PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I; InterPro IPR005651; KEGG: ddf:DEFDS_0512 hypothetical protein; PFAM: Protein of unknown function DUF343; SPTR: Putative uncharacterized protein YP_004603239.1 PFAM: Trm112p-like protein; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603240.1 PFAM: Transposase DDE domain; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR010656:IPR004681; KEGG: ddf:DEFDS_0684 C4-dicarboxylate transporter large subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: C4-dicarboxylate transporter, large subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit YP_004603241.1 PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; InterPro IPR007387; KEGG: ddf:DEFDS_0683 C4-dicarboxylate transporter small subunit; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: C4-dicarboxylate transporter, small subunit YP_004603242.1 PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389:IPR004682; KEGG: ddf:DEFDS_0682 C4-dicarboxylate transporter substrate-binding protein; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: C4-dicarboxylate transporter, substrate-binding protein; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit YP_004603243.1 PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; manually curated YP_004603244.1 PFAM: ABC transporter; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: sfu:Sfum_2735 ABC-3 protein; PFAM: ABC-3; SPTR: ABC-3 protein YP_004603245.1 PFAM: ABC 3 transport family; COGs: COG0219 rRNA methylase (SpoU class); InterPro IPR001537; KEGG: cni:Calni_1256 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: Putative tRNA (cytidine/uridine-2'-O-)-methyltransferase Calni_1256 YP_004603246.1 PFAM: SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, putative, group 2; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR013656:IPR003661:IPR003594; KEGG: ddf:DEFDS_1377 hypothetical protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Putative uncharacterized protein YP_004603247.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: ddf:DEFDS_1376 two-component system, NtrC family, response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two-component system, NtrC family, response regulator YP_004603248.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389:IPR004682; KEGG: cni:Calni_1703 trap dicarboxylate transporter, dCTP subunit; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: TRAP dicarboxylate transporter, DctP subunit; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit YP_004603249.1 PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family YP_004603250.1 KEGG: cni:Calni_1704 trap C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP C4-dicarboxylate transport system permease DctM subunit YP_004603251.1 COGs: COG2264 Ribosomal protein L11 methylase; InterPro IPR010456; KEGG: cni:Calni_1255 ribosomal L11 methyltransferase; PFAM: Ribosomal L11 methyltransferase; SPTR: Ribosomal L11 methyltransferase YP_004603252.1 PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase; InterPro IPR004843; KEGG: ddf:DEFDS_1372 metallophosphoesterase; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase YP_004603253.1 PFAM: Calcineurin-like phosphoesterase; COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: cni:Calni_1254 hypothetical protein; PFAM: Ribosomal RNA small subunit methyltransferase E; SPTR: Putative uncharacterized protein; TIGRFAM: Ribosomal RNA small subunit methyltransferase E YP_004603254.1 PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family; COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125; KEGG: cni:Calni_1253 cmp/dcmp deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding protein YP_004603255.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; InterPro IPR002514; KEGG: has:Halsa_0053 transposase IS3/IS911 family protein; PFAM: Transposase IS3/IS911; SPTR: Transposase IS3/IS911 family protein YP_004603256.1 PFAM: Transposase; COGs: COG2801 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: afl:Aflv_2449 transposase; PFAM: Integrase, catalytic core; SPTR: Transposase; manually curated YP_004603257.1 PFAM: Integrase core domain YP_004603258.1 COGs: COG1651 Protein-disulfide isomerase; KEGG: cni:Calni_1066 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603259.1 COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; HAMAP: Acetyl-CoA carboxylase, alpha subunit; InterPro IPR001095:IPR020582; KEGG: ddf:DEFDS_1173 acetyl-CoA carboxylase carboxyl transferase subunit alpha; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; TIGRFAM: Acetyl-CoA carboxylase, alpha subunit YP_004603260.1 PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); HAMAP: DNA mismatch repair protein mutL; InterPro IPR003594:IPR013507:IPR014790:IPR014763; KEGG: cni:Calni_1068 DNA mismatch repair protein MutL; PFAM: MutL, C-terminal, dimerisation; DNA mismatch repair protein, C-terminal; ATP-binding region, ATPase-like; SPTR: DNA mismatch repair protein mutL; TIGRFAM: DNA mismatch repair protein, N-terminal YP_004603261.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL; COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; HAMAP: tRNA dimethylallyltransferase; InterPro IPR002627:IPR018022; KEGG: ddf:DEFDS_1175 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase YP_004603262.1 PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase; COGs: COG1923 Uncharacterized host factor I protein; InterPro IPR001163:IPR005001; KEGG: ddf:DEFDS_1085 RNA-binding protein Hfq; PFAM: Like-Sm ribonucleoprotein, core; SPTR: Protein hfq; TIGRFAM: Host factor Hfq YP_004603263.1 PFAM: LSM domain; TIGRFAM: RNA chaperone Hfq; KEGG: ddf:DEFDS_1086 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603264.1 KEGG: cni:Calni_1667 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603265.1 InterPro IPR007060; KEGG: ddf:DEFDS_1089 cell division protein FtsB; PFAM: Septum formation initiator; SPTR: Cell division protein FtsB YP_004603266.1 PFAM: Septum formation initiator; COGs: COG1570 Exonuclease VII large subunit; HAMAP: Exodeoxyribonuclease 7 large subunit; InterPro IPR004365:IPR020579:IPR003753; KEGG: ddf:DEFDS_1090 exodeoxyribonuclease VII large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Exodeoxyribonuclease 7 large subunit; TIGRFAM: Exonuclease VII, large subunit YP_004603267.1 PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit; COGs: COG0782 Transcription elongation factor; HAMAP: Transcription elongation factor greA; InterPro IPR001437:IPR006359; KEGG: ddf:DEFDS_1091 transcription elongation factor GreA; PFAM: Transcription elongation factor, GreA/GreB region, prokaryotic; SPTR: Transcription elongation factor greA; TIGRFAM: Prokaryotic transcription elongation factor GreA YP_004603268.1 PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA; This gene is disrupted by insertion of repetitive element; manually curated YP_004603269.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462:IPR004570; KEGG: cni:Calni_1662 cdp-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR:CDP-diacylglycerol/glycerol-3-phosphate3-phosp hatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004603270.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG2006 conserved hypothetical protein; InterPro IPR007160:IPR001450; KEGG: dap:Dacet_1321 hypothetical protein; PFAM: Protein of unknown function DUF362; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein YP_004603271.1 PFAM: Domain of unknown function (DUF362); COGs: COG0344 membrane protein; HAMAP: Protein of unknown function DUF205; InterPro IPR003811:IPR020788; KEGG: ddf:DEFDS_1095 hypothetical protein; PFAM: Protein of unknown function DUF205; SPTR: Glycerol-3-phosphate acyltransferase; TIGRFAM: Membrane protein YgiH YP_004603272.1 PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase; COGs: COG0117 Pyrimidine deaminase; InterPro IPR002125:IPR002734:IPR004794:IPR011549; KEGG: cni:Calni_1660 riboflavin biosynthesis protein RibD; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; CMP/dCMP deaminase, zinc-binding; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: Riboflavin biosynthesis protein RibD; Riboflavin-specific deaminase, C-terminal YP_004603273.1 PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD; COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: ddf:DEFDS_1097 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein YP_004603274.1 PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit; COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; HAMAP: GTP cyclohydrolase-2; InterPro IPR000422:IPR000926; KEGG: ddf:DEFDS_1098 riboflavin biosynthesis bifunctional protein RibBA; PFAM: DHBP synthase RibB; GTP cyclohydrolase II; SPTR: Riboflavin biosynthesis bifunctional protein RibBA; TIGRFAM: DHBP synthase RibB; GTP cyclohydrolase II YP_004603275.1 PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; COGs: COG0054 Riboflavin synthase beta-chain; HAMAP: 6,7-dimethyl-8-ribityllumazine synthase; InterPro IPR002180; KEGG: cni:Calni_1657 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004603276.1 PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; COGs: COG0781 Transcription termination factor; HAMAP: N utilization substance protein B-like protein; InterPro IPR006027:IPR011605; KEGG: dap:Dacet_1327 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: N utilization substance protein B homolog; TIGRFAM: NusB antitermination factor YP_004603277.1 PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB; KEGG: cni:Calni_1655 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603278.1 KEGG: ddf:DEFDS_1102 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603279.1 COGs: COG3481 HD-superfamily hydrolase; InterPro IPR004365:IPR006674:IPR003607:IPR006675; KEGG: ddf:DEFDS_1104 HAD-superfamily hydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: HAD-superfamily hydrolase; TIGRFAM: HDIG YP_004603280.1 PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR006042; KEGG: ddf:DEFDS_1105 uracil transporter; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil transporter; TIGRFAM: Xanthine/uracil permease YP_004603281.1 PFAM: Permease family; TIGRFAM: uracil-xanthine permease; COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR000836:IPR005765; KEGG: cni:Calni_1651 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: Uracil phosphoribosyl transferase YP_004603282.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: cni:Calni_0487 major facilitator superfamily mfs_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1 YP_004603283.1 PFAM: Major Facilitator Superfamily; KEGG: ssm:Spirs_1067 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603284.1 COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: ssm:Spirs_1066 sodium:neurotransmitter symporter; PFAM: Sodium:neurotransmitter symporter; SPTR: Transporter YP_004603285.1 PFAM: Sodium:neurotransmitter symporter family; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR002912:IPR006236; KEGG: ddf:DEFDS_0857 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004603286.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: ddf:DEFDS_0856 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047 YP_004603287.1 PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: dap:Dacet_2223 ROK family protein; PFAM: ROK; PRIAM: Glucokinase; SPTR: ROK family protein YP_004603288.1 PFAM: ROK family; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153:IPR003148:IPR006037; KEGG: gfo:GFO_1965 KefB-and KefC-like glutathione-regulated potassium-efflux system protein; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: KefB-and KefC-like glutathione-regulated potassium-efflux system protein YP_004603289.1 PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family; COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR002912:IPR005789; KEGG: ddf:DEFDS_2182 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Amino acid-binding ACT; SPTR: Threonine dehydratase; TIGRFAM: Threonine dehydratase II YP_004603290.1 PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603291.1 PFAM: Transposase domain (DUF772); COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006199:IPR019759:IPR006200; KEGG: dap:Dacet_1375 transcriptional repressor, LexA family; PFAM: LexA DNA-binding region; Peptidase S24/S26A/S26B, conserved region; SPTR: LexA repressor; TIGRFAM: Peptidase S24, LexA repressor YP_004603292.1 PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA; KEGG: cni:Calni_0692 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603293.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; HAMAP: DNA polymerase IV; InterPro IPR001126; KEGG: ddf:DEFDS_0477 DNA polymerase IV; PFAM: DNA-repair protein, UmuC-like; PRIAM: DNA-directed DNA polymerase; SPTR: DNA polymerase IV YP_004603294.1 PFAM: impB/mucB/samB family C-terminal; IMS family HHH motif; impB/mucB/samB family YP_004603295.1 InterPro IPR001450; KEGG: ddf:DEFDS_1334 hypothetical protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein YP_004603296.1 PFAM: 4Fe-4S binding domain; COGs: COG3381 Uncharacterized component of anaerobic dehydrogenase; KEGG: ddf:DEFDS_1333 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603297.1 PFAM: Nitrate reductase delta subunit; InterPro IPR006311 YP_004603298.1 PFAM: TAT (twin-arginine translocation) pathway signal sequence; TIGRFAM: formate dehydrogenase region TAT target; Tat (twin-arginine translocation) pathway signal sequence; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR019546:IPR006963:IPR006656:IPR006657:IPR 006311; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Twin-arginine translocation pathway, signal sequence, subgroup; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit YP_004603299.1 PFAM: TAT (twin-arginine translocation) pathway signal sequence; Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450; KEGG: ddf:DEFDS_1330 formate dehydrogenase subunit beta; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Formate dehydrogenase, beta subunit YP_004603300.1 PFAM: 4Fe-4S binding domain; COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR006471; KEGG: ddf:DEFDS_1329 formate dehydrogenase subunit gamma; SPTR: Formate dehydrogenase, gamma subunit; TIGRFAM: Formate dehydrogenase, gamma subunit YP_004603301.1 PFAM: Prokaryotic cytochrome b561; TIGRFAM: formate dehydrogenase, gamma subunit; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603302.1 PFAM: Transposase domain (DUF772); COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: pmx:PERMA_0406 oligopeptidase A; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; PRIAM: Oligopeptidase A; SPTR: Oligopeptidase A YP_004603303.1 PFAM: Peptidase family M3; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR003660:IPR003594; KEGG: swo:Swol_0353 putative CheA signal transduction histidine kinases; PFAM: HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Putative CheA signal transduction histidine kinases YP_004603304.1 PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; KEGG: mag:amb2637 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603305.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: mag:amb2638 FOG: CheY-like receiver; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: FOG: CheY-like receiver YP_004603306.1 PFAM: Response regulator receiver domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dma:DMR_28660 GGDEF domain protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted YP_004603307.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0348 Polyferredoxin; InterPro IPR001450; KEGG: dap:Dacet_0868 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004603308.1 COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR018317:IPR004479; KEGG: cni:Calni_1217 ExsB protein; PFAM: Queuosine synthesis-like; SPTR: 7-cyano-7-deazaguanine synthase; TIGRFAM: Exoenzyme S synthesis protein B/queuosine synthesis YP_004603309.1 PFAM: ExsB; TIGRFAM: queuosine biosynthesis protein QueC; COGs: COG0205 6-phosphofructokinase; HAMAP: 6-phosphofructokinase; InterPro IPR000023:IPR012828; KEGG: ddf:DEFDS_0940 6-phosphofructokinase; PFAM: Phosphofructokinase; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase; TIGRFAM: 6-phosphofructokinase YP_004603310.1 PFAM: Phosphofructokinase; TIGRFAM: 6-phosphofructokinase; COGs: COG2096 conserved hypothetical protein; InterPro IPR002779:IPR017858; KEGG: cni:Calni_1215 ATP/cobalamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type; SPTR: ATP/cobalamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal YP_004603311.1 PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; COGs: COG1610 conserved hypothetical protein; InterPro IPR019004; KEGG: ddf:DEFDS_1583 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603312.1 PFAM: Yqey-like protein; InterPro IPR003825; KEGG: ddf:DEFDS_1584 colicin V production protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein YP_004603313.1 PFAM: Colicin V production protein; COGs: COG1193 Mismatch repair ATPase (MutS family); InterPro IPR000432:IPR002625:IPR007696; KEGG: ddf:DEFDS_1585 DNA mismatch repair protein MutS2; PFAM: Smr protein/MutS2 C-terminal; DNA mismatch repair protein MutS, C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; Smr protein/MutS2 C-terminal; SPTR: DNA mismatch repair protein MutS2 YP_004603314.1 PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: ddf:DEFDS_1285 MntR family transcriptional regulator; PFAM: Iron dependent repressor; SMART: Iron dependent repressor; SPTR: Transcriptional regulator, MntR family YP_004603315.1 PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1647 Esterase/lipase; KEGG: ddf:DEFDS_1284 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603316.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455:IPR000304; KEGG: ddf:DEFDS_1283 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: Delta 1-pyrroline-5-carboxylate reductase YP_004603317.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase; COGs: COG1309 Transcriptional regulator; InterPro IPR001647:IPR013570; KEGG: ddf:DEFDS_1282 TetR family transcriptional regulator; PFAM: Transcriptional regulator, YsiA, C-terminal; Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family YP_004603318.1 PFAM: YsiA-like protein, C-terminal region; Bacterial regulatory proteins, tetR family; COGs: COG2985 permease; InterPro IPR006512:IPR006037; KEGG: cni:Calni_1187 yide/ybjl duplication; PFAM: YidE/YbjL duplication; Regulator of K+ conductance, C-terminal; SPTR: YidE/YbjL duplication; TIGRFAM: YidE/YbjL duplication YP_004603319.1 PFAM: Predicted Permease Membrane Region; TrkA-C domain; TIGRFAM: AspT/YidE/YbjL antiporter duplication domain; KEGG: aae:aq_2066 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603320.1 InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603321.1 PFAM: Transposase DDE domain; manually curated YP_004603322.1 PFAM: LysE type translocator YP_004603323.1 PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA); COGs: COG4175 ABC-type proline/glycine betaine transport system ATPase component; InterPro IPR003439:IPR000644:IPR003593:IPR005892; KEGG: dsa:Desal_0676 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter-like; Cystathionine beta-synthase, core; PRIAM: Quaternary-amine-transporting ATPase; SMART: ATPase, AAA+ type, core; Cystathionine beta-synthase, core; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: Glycine betaine/L-proline transport ATP-binding subunit YP_004603324.1 PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit; COGs: COG4176 ABC-type proline/glycine betaine transport system permease component; InterPro IPR000515; KEGG: drt:Dret_2272 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004603325.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG2113 ABC-type proline/glycine betaine transport systems periplasmic components; InterPro IPR007210; KEGG: drt:Dret_2271 substrate-binding region of ABC-type glycine betaine transport system; PFAM: ABC-type glycine betaine transport system, substrate-binding region; SPTR: Substrate-binding region of ABC-type glycine betaine transport system YP_004603326.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439:IPR013563:IPR003593:IPR010066; KEGG: dap:Dacet_1755 ABC transporter related protein; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal YP_004603327.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; KEGG: ddf:DEFDS_1488 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603328.1 COGs: COG0358 DNA primase; InterProIPR002694:IPR013264:IPR006171:IPR006154:IPR 006295; KEGG: ddf:DEFDS_1487 DNA primase; SPTR: DNA primase; TIGRFAM: DNA primase, DnaG YP_004603329.1 PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR007127:IPR009042:IPR007627:IPR007624:IPR 007630:IPR014284:IPR012760; KEGG: ddf:DEFDS_1486 DNA-directed RNA polymerase sigma 70 factor; PFAM: RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma factor 70, region 1.1; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD, C-terminal; RNA polymerase sigma-70 YP_004603330.1 PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain; COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754:IPR014732; KEGG: cni:Calni_0988 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 1, core YP_004603331.1 PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 1; COGs: COG0461 Orotate phosphoribosyltransferase; HAMAP: Orotate phosphoribosyltransferase; InterPro IPR000836:IPR006273; KEGG: cni:Calni_0989 orotate phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: Orotate phosphoribosyltransferase, Thermus type YP_004603332.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase, Thermus family; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR001789:IPR003661:IPR003594; KEGG: ddf:DEFDS_0953 hypothetical protein; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Putative uncharacterized protein YP_004603333.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: ddf:DEFDS_0949 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted YP_004603334.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0820 Fe-S-cluster redox enzyme; HAMAP: Ribosomal RNA large subunit methyltransferase RlmN; InterPro IPR004383:IPR007197; KEGG: cni:Calni_0271 23S rRNA m(2)a-2503 methyltransferase; PFAM: Radical SAM; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: Ribosomal RNA large subunit methyltransferase RlmN YP_004603335.1 PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase; InterPro IPR000551; KEGG: cni:Calni_1033 regulatory protein MerR; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Regulatory protein MerR YP_004603336.1 PFAM: MerR family regulatory protein; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dap:Dacet_1204 histone family protein DNA-binding protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein YP_004603337.1 PFAM: Bacterial DNA-binding protein; TIGRFAM: integration host factor, alpha subunit; KEGG: ddf:DEFDS_1533 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603338.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR005517:IPR000640:IPR004540:IPR 005225; KEGG: ddf:DEFDS_1534 translation elongation factor G; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G 1; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein YP_004603339.1 PFAM: Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107:IPR010201; KEGG: ddf:DEFDS_1535 membrane protease subunit HflK; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Membrane protease subunit HflK; TIGRFAM: HflK YP_004603340.1 PFAM: SPFH domain / Band 7 family; TIGRFAM: HflK protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107:IPR010200; KEGG: ddf:DEFDS_1536 membrane protease subunit HflC; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Membrane protease subunit HflC; TIGRFAM: HflC YP_004603341.1 PFAM: SPFH domain / Band 7 family; TIGRFAM: HflC protein; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: ddf:DEFDS_1176 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase YP_004603342.1 PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304:IPR006124:IPR013371:IPR004456; KEGG: ddf:DEFDS_1177 phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme; PRIAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal YP_004603343.1 PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal form; proposed homoserine kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: ddf:DEFDS_1178 aspartate kinase monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class YP_004603344.1 PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005675; KEGG: cni:Calni_0870 (R)-citramalate synthase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Pyruvate carboxyltransferase; PRIAM: (R)-citramalate synthase; SPTR: (R)-citramalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related YP_004603345.1 PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0796 Glutamate racemase; HAMAP: Glutamate racemase; InterPro IPR004391:IPR015942; KEGG: sul:SYO3AOP1_0987 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: Glutamate racemase; TIGRFAM: Glutamate racemase YP_004603346.1 PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase; InterPro IPR013509:IPR000788:IPR013344; KEGG: ddf:DEFDS_1169 ribonucleoside-diphosphate reductase alpha chain; PFAM: Ribonucleotide reductase large subunit, C-terminal; Ribonucleotide reductase large subunit, N-terminal; PRIAM: Ribonucleoside-diphosphate reductase; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent YP_004603347.1 PFAM: Ribonucleotide reductase, all-alpha domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; KEGG: cni:Calni_1519 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603348.1 InterPro IPR003088; KEGG: ddf:DEFDS_1171 cytochrome c family protein; PFAM: Cytochrome c, class I; SPTR: Cytochrome c family protein YP_004603349.1 PFAM: Cytochrome c; Bacterial Cytochrome Ubiquinol Oxidase; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: cni:Calni_1860 php domain protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein YP_004603350.1 PFAM: PHP domain; KEGG: ddf:DEFDS_0780 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603351.1 COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR002880:IPR011766:IPR001450:IPR017721; KEGG: ddf:DEFDS_0781 indolepyruvate ferredoxin oxidoreductase subunit alpha; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Indolepyruvate ferredoxin oxidoreductase, alpha subunit; TIGRFAM: Indolepyruvate ferredoxin oxidoreductase, alpha subunit YP_004603352.1 PFAM: domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: dap:Dacet_1341 pyruvate/ketoisovalerate oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Pyruvate/ketoisovalerate oxidoreductase YP_004603353.1 PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: dap:Dacet_1342 PHP domain protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein YP_004603354.1 PFAM: PHP domain; COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; HAMAP: Molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: ddf:DEFDS_1017 molybdopterin-guanine dinucleotide biosynthesis protein A; SPTR: Probable molybdopterin-guanine dinucleotide biosynthesis protein A YP_004603355.1 COGs: COG1526 Uncharacterized protein required for formate dehydrogenase activity; InterPro IPR003786; KEGG: ddf:DEFDS_1018 formate dehydrogenase accessory protein FdhD; PFAM: Formate dehydrogenase, subunit FdhD; SPTR: Formate dehydrogenase accessory protein FdhD; TIGRFAM: Formate dehydrogenase, subunit FdhD YP_004603356.1 PFAM: FdhD/NarQ family; TIGRFAM: formate dehydrogenase family accessory protein FdhD; COGs: COG0556 Helicase subunit of the DNA excision repair complex; HAMAP: Excinuclease ABC, B subunit; InterProIPR004807:IPR006935:IPR001650:IPR001943:IPR 014001; KEGG: dap:Dacet_0842 excinuclease ABC, B subunit; PFAM: DNA/RNA helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: UvrABC system protein B; TIGRFAM: Excinuclease ABC, B subunit YP_004603357.1 PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: ddf:DEFDS_0662 penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein 1A; TIGRFAM: Penicillin-binding protein 1A YP_004603358.1 PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR003594; KEGG: ddf:DEFDS_0661 two-component system, NtrC family, response regulator GlnL; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Two-component system, NtrC family, response regulator GlnL YP_004603359.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: dap:Dacet_2326 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family YP_004603360.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004603361.1 InterPro IPR001387:IPR013096; KEGG: ddf:DEFDS_0680 transcriptional regulator; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator YP_004603362.1 PFAM: Cupin domain; Helix-turn-helix; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: cni:Calni_1121 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603363.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661; KEGG: cni:Calni_1120 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Integral membrane sensor signal transduction histidine kinase YP_004603364.1 PFAM: His Kinase A (phosphoacceptor) domain; InterPro IPR001387:IPR013096; KEGG: dap:Dacet_1432 transcriptional regulator, XRE family; PFAM: Cupin 2, conserved barrel; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family YP_004603365.1 PFAM: Cupin domain; Helix-turn-helix; COGs: COG0413 Ketopantoate hydroxymethyltransferase; HAMAP: Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: ddf:DEFDS_0843 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: Ketopantoate hydroxymethyltransferase YP_004603366.1 PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; COGs: COG0414 Panthothenate synthetase; HAMAP: Pantoate-beta-alanine ligase; InterPro IPR003721; KEGG: dap:Dacet_1430 pantoate/beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: Pantoate-beta-alanine ligase YP_004603367.1 PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase; COGs: COG0853 Aspartate 1-decarboxylase; HAMAP: Aspartate decarboxylase; InterPro IPR003190; KEGG: cni:Calni_1116 L-aspartate 1-decarboxylase; PFAM: Aspartate decarboxylase; PRIAM: Aspartate 1-decarboxylase; SPTR: Aspartate 1-decarboxylase; TIGRFAM: Aspartate decarboxylase YP_004603368.1 PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase; COGs: COG1200 RecG-like helicase; InterPro IPR011545:IPR001650:IPR014001:IPR004609; KEGG: cni:Calni_0994 ATP-dependent DNA helicase RecG; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent DNA helicase RecG; TIGRFAM: DNA helicase, ATP-dependent, RecG YP_004603369.1 PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG; KEGG: ddf:DEFDS_1216 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603370.1 COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR011545:IPR001650:IPR018973:IPR014001; KEGG: dap:Dacet_1226 DEAD/DEAH box helicase domain protein; PFAM: Protein of unknown function DUF1998; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein YP_004603371.1 PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR009042:IPR007627:IPR007624:IPR007630:IPR 014284; KEGG: ddf:DEFDS_1924 DNA-directed RNA polymerase sigma 70 factor; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70 YP_004603372.1 PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176:IPR003959:IPR013093:IPR019489:IPR 003593:IPR017730; KEGG: ddf:DEFDS_1925 ATP-dependent Clp protease ATP-binding subunit ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpB; TIGRFAM: Chaperonin ClpB YP_004603373.1 PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: ddf:DEFDS_1926 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator, MerR family YP_004603374.1 PFAM: MerR family regulatory protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone protein dnaJ; InterPro IPR001623:IPR001305:IPR002939:IPR012724; KEGG: ddf:DEFDS_1927 molecular chaperone DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich region; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ 1; TIGRFAM: Chaperone DnaJ YP_004603375.1 PFAM: DnaJ central domain (4 repeats); DnaJ domain; DnaJ C terminal region; TIGRFAM: chaperone protein DnaJ; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ddf:DEFDS_1928 heat shock protein Hsp20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20 YP_004603376.1 PFAM: Hsp20/alpha crystallin family; COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR003538:IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; PFAM: Gram-negative bacterial tonB protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal YP_004603377.1 PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; InterPro IPR002804; KEGG: ddf:DEFDS_1459 hypothetical protein; PFAM: Archease, tRNA m5C methyltransferase chaperone; SPTR: Putative uncharacterized protein YP_004603378.1 PFAM: Archease protein family (DUF101/UPF0211); KEGG: ddf:DEFDS_0820 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603379.1 KEGG: ddf:DEFDS_0821 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004603380.1 PFAM: Class III cytochrome C family; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603381.1 PFAM: Transposase DDE domain; manually curated YP_004603382.1 PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N'; COGs: COG0407 Uroporphyrinogen-III decarboxylase; HAMAP: Uroporphyrinogen decarboxylase HemE; InterPro IPR006361:IPR000257; KEGG: ddf:DEFDS_0318 uroporphyrinogen decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D); PRIAM: Uroporphyrinogen decarboxylase; SPTR: Uroporphyrinogen decarboxylase; TIGRFAM: Uroporphyrinogen decarboxylase HemE YP_004603383.1 PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: uroporphyrinogen decarboxylase; methyltransferase, MtaA/CmuA family; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); HAMAP: Ferrochelatase; InterPro IPR001015; KEGG: ddf:DEFDS_0319 ferrochelatase; PFAM: Ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: Ferrochelatase YP_004603384.1 PFAM: Ferrochelatase; TIGRFAM: ferrochelatase; COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: ddf:DEFDS_0320 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related YP_004603385.1 PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR003382:IPR004507; KEGG: dap:Dacet_1255 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Phenylacrylic acid decarboxylase YP_004603386.1 PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; KEGG: ddf:DEFDS_0322 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603387.1 KEGG: ddf:DEFDS_0323 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603388.1 KEGG: ddf:DEFDS_0325 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603389.1 KEGG: cni:Calni_0442 cytochrome c family protein; SPTR: Cytochrome c family protein YP_004603390.1 COGs: COG4121 conserved hypothetical protein; InterPro IPR008471; KEGG: ddf:DEFDS_0197 hypothetical protein; PFAM: Protein of unknown function DUF752; SPTR: Putative uncharacterized protein YP_004603391.1 PFAM: Protein of unknown function (DUF752); COGs: COG0029 Aspartate oxidase; InterPro IPR003953:IPR004112:IPR005288; KEGG: cni:Calni_1125 L-aspartate oxidase; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: L-aspartate oxidase; SPTR: L-aspartate oxidase; TIGRFAM: L-aspartate oxidase YP_004603392.1 PFAM: domain; FAD binding domain; TIGRFAM: L-aspartate oxidase; KEGG: ddf:DEFDS_0199 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603393.1 InterPro IPR007197; KEGG: dap:Dacet_0745 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein YP_004603394.1 COGs: COG0148 Enolase; HAMAP: Enolase; InterPro IPR000941:IPR020811:IPR020810; KEGG: ddf:DEFDS_0201 enolase; PFAM: Enolase, C-terminal; Enolase, N-terminal; PRIAM: Phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: Enolase YP_004603395.1 PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase; COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: ddf:DEFDS_1140 peptidase M29, aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Peptidase M29, aminopeptidase II YP_004603396.1 PFAM: Thermophilic metalloprotease (M29); COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: cni:Calni_0866 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Ribonuclease BN YP_004603397.1 PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN); COGs: COG3381 Uncharacterized component of anaerobic dehydrogenase; InterPro IPR010395; KEGG: ddf:DEFDS_1625 cytoplasmic chaperone TorD; SPTR: Cytoplasmic chaperone TorD YP_004603398.1 PFAM: Nitrate reductase delta subunit; KEGG: ddf:DEFDS_1624 cytochrome c family protein; SPTR: Cytochrome c family protein YP_004603399.1 KEGG: ddf:DEFDS_1623 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603400.1 PFAM: Protein of unknown function (DUF3373); COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cni:Calni_0613 transcriptional regulator, badm/rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2 YP_004603401.1 PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: dvl:Dvul_1399 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase YP_004603402.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004603403.1 PFAM: Aminotransferase class I and II; InterPro IPR002145; PFAM: CopG-like DNA-binding YP_004603404.1 PFAM: Ribbon-helix-helix protein, copG family; COGs: COG2206 HD-GYP domain; InterPro IPR001789:IPR006674:IPR003607:IPR006675; KEGG: ddf:DEFDS_1712 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Signal transduction response regulator, receiver region; SMART: Metal-dependent phosphohydrolase, HD region; Signal transduction response regulator, receiver region; SPTR: Putative uncharacterized protein; TIGRFAM: HDIG YP_004603405.1 PFAM: HD domain; Response regulator receiver domain; TIGRFAM: uncharacterized domain HDIG YP_004603406.1 PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR011912; KEGG: ddf:DEFDS_0970 ADP-glyceromanno-heptose 6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: ADP-glyceromanno-heptose 6-epimerase; SPTR: ADP-glyceromanno-heptose 6-epimerase; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase YP_004603407.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; COGs: COG1586 S-adenosylmethionine decarboxylase; HAMAP: S-adenosylmethionine decarboxylase proenzyme; InterPro IPR003826:IPR017716; KEGG: ddf:DEFDS_0969 adenosylmethionine decarboxylase; PFAM: S-adenosylmethionine decarboxylase, bacterial/archaeal; PRIAM: Adenosylmethionine decarboxylase; SPTR: S-adenosylmethionine decarboxylase proenzyme; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme YP_004603408.1 PFAM: S-adenosylmethionine decarboxylase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme, Bacillus form; COGs: COG1945 conserved hypothetical protein; HAMAP: Pyruvoyl-dependent arginine decarboxylase; InterPro IPR002724; KEGG: mvu:Metvu_0499 pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Pyruvoyl-dependent arginine decarboxylase; TIGRFAM: Pyruvoyl-dependent arginine decarboxylase YP_004603409.1 PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; COGs: COG0421 Spermidine synthase; HAMAP: Spermidine synthase; InterPro IPR001045; KEGG: ddf:DEFDS_0968 spermidine synthase; PFAM: Spermine synthase; SPTR: Spermidine synthase; TIGRFAM: Spermine synthase YP_004603410.1 PFAM: Spermine/spermidine synthase; TIGRFAM: spermidine synthase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005925; KEGG: ddf:DEFDS_0967 agmatinase; PFAM: Ureohydrolase; PRIAM: Agmatinase; SPTR: Agmatinase; TIGRFAM: Putative agmatinase YP_004603411.1 PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: cni:Calni_1071 histone family protein DNA-binding protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein YP_004603412.1 PFAM: Bacterial DNA-binding protein; InterPro IPR001387:IPR013096; KEGG: cni:Calni_1070 helix-turn-helix domain protein; PFAM: Cupin 2, conserved barrel; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Helix-turn-helix domain protein YP_004603413.1 PFAM: Cupin domain; Helix-turn-helix; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: ddf:DEFDS_0964 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase YP_004603414.1 PFAM: AMP-binding enzyme; TIGRFAM: phenylacetate-CoA ligase; COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: ddf:DEFDS_0963 hypothetical protein; PFAM: Amino acid-binding ACT; SPTR: Putative uncharacterized protein YP_004603415.1 PFAM: ACT domain; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: ddf:DEFDS_0962 branched-chain amino acid ABC transporter substrate-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: Branched-chain amino acid ABC transporter, substrate-binding protein YP_004603416.1 PFAM: Receptor family ligand binding region; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: ddf:DEFDS_0962 branched-chain amino acid ABC transporter substrate-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: Branched-chain amino acid ABC transporter, substrate-binding protein YP_004603417.1 PFAM: Receptor family ligand binding region; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: cni:Calni_0893 amino acid/amide abc transporter membrane protein 1, haat family; PFAM: Bacterial inner-membrane translocator; SPTR: Amino acid/amide ABC transporter membrane protein 1, HAAT family YP_004603418.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: cni:Calni_0894 amino acid/amide abc transporter membrane protein 2, haat family; PFAM: Bacterial inner-membrane translocator; SPTR: Amino acid/amide ABC transporter membrane protein 2, HAAT family YP_004603419.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: cni:Calni_0895 amino acid/amide abc transporter ATP-binding protein 1, haat family; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family YP_004603420.1 PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: cni:Calni_0896 amino acid/amide abc transporter ATP-binding protein 2, haat family; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family YP_004603421.1 PFAM: ABC transporter; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: ddf:DEFDS_0957 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase YP_004603422.1 PFAM: AMP-binding enzyme; COGs: COG1896 hydrolase of HD superfamily; InterPro IPR006674; KEGG: ddf:DEFDS_0956 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Putative uncharacterized protein YP_004603423.1 KEGG: cni:Calni_0899 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603424.1 COGs: COG1283 Na+/phosphate symporter; InterPro IPR003841:IPR008170:IPR004633; KEGG: ddf:DEFDS_0081 Na:phosphate symporter; PFAM: Na/Pi-cotransporter; PhoU; SPTR: Na:phosphate symporter; TIGRFAM: Na/Pi co-transporter II-related YP_004603425.1 PFAM: PhoU domain; Na+/Pi-cotransporter; TIGRFAM: Na/Pi-cotransporter; COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: ddf:DEFDS_1930 phosphatase Ppx/GppA family; PFAM: Ppx/GppA phosphatase; SPTR: Phosphatase, Ppx/GppA family YP_004603426.1 PFAM: Ppx/GppA phosphatase family; COGs: COG4399 conserved hypothetical protein; InterPro IPR007383; KEGG: ddf:DEFDS_1931 hypothetical protein; PFAM: Protein of unknown function DUF445, transmembrane; SPTR: Putative uncharacterized protein YP_004603427.1 PFAM: Protein of unknown function (DUF445); COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: ddf:DEFDS_1002 peptidase M50 family; PFAM: Peptidase M50; SPTR: Peptidase, M50 family YP_004603428.1 PFAM: Peptidase family M50; COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002305:IPR002306; KEGG: ddf:DEFDS_1003 tryptophanyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Tryptophanyl-tRNA synthetase; TIGRFAM: Tryptophanyl-tRNA synthetase, class Ib YP_004603429.1 PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase; COGs: COG1354 conserved hypothetical protein; HAMAP: Segregation and condensation protein A; InterPro IPR003768; KEGG: dap:Dacet_1364 chromosome segregation and condensation protein ScpA; PFAM: Prokaryotic chromosome segregation/condensation protein ScpA; SPTR: Chromosome segregation and condensation protein ScpA YP_004603430.1 PFAM: ScpA/B protein; COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: dap:Dacet_1365 chromosome segregation and condensation protein, ScpB; PFAM: Chromosome segregation/condensation protein ScpB, prokaryote; SPTR: Chromosome segregation and condensation protein, ScpB; TIGRFAM: Chromosome segregation/condensation protein ScpB, prokaryote YP_004603431.1 PFAM: Putative transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: dap:Dacet_1366 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F YP_004603432.1 PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: ddf:DEFDS_1007 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: 6-pyruvoyl-tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD YP_004603433.1 PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein; COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: ddf:DEFDS_1008 hypothetical protein; PFAM: Radical SAM; SPTR: Putative uncharacterized protein YP_004603434.1 PFAM: Radical SAM superfamily; InterPro IPR013105:IPR001440:IPR019734; KEGG: ddf:DEFDS_1009 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Putative uncharacterized protein YP_004603435.1 COGs: COG3267 Type II secretory pathway component ExeA (predicted ATPase); InterPro IPR011579:IPR003593; KEGG: ddf:DEFDS_1010 general secretion pathway protein A; SMART: ATPase, AAA+ type, core; SPTR: General secretion pathway protein A YP_004603436.1 PFAM: Archaeal ATPase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterPro IPR003660:IPR003661:IPR003594; KEGG: dap:Dacet_1368 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Integral membrane sensor signal transduction histidine kinase YP_004603437.1 PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: ddf:DEFDS_1012 two-component, sigma54 specific, transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two-component, sigma54 specific, transcriptional regulator YP_004603438.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135:IPR005720; KEGG: cni:Calni_1008 dihydroorotate oxidase B, catalytic subunit; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; PRIAM: Dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase; TIGRFAM: Dihydroorotate dehydrogenase, class 1, core YP_004603439.1 PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: ddf:DEFDS_1218 dihydroorotate dehydrogenase electron transfer subunit; PFAM: Oxidoreductase FAD/NAD(P)-binding; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Dihydroorotate dehydrogenase electron transfer subunit YP_004603440.1 PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481:IPR005479:IPR005480:IPR011607:IPR 012607:IPR006275; KEGG: ddf:DEFDS_1217 carbamoylphosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Ribosomal protein S22; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent YP_004603441.1 PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR000014; KEGG: cni:Calni_1645 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; SPTR: Signal transduction histidine kinase, nitrogen specific, NtrB YP_004603442.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: ddf:DEFDS_1111 type IV pilus assembly protein PilC; PFAM: Type II secretion system F domain; SPTR: Type IV pilus assembly protein PilC YP_004603443.1 PFAM: Bacterial type II secretion system protein F domain; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR001482:IPR006321; KEGG: ddf:DEFDS_1110 twitching motility protein PilT; PFAM: Type II secretion system protein E; SPTR: Twitching motility protein PilT; TIGRFAM: Pilus retraction protein PilT YP_004603444.1 PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482:IPR003593:IPR013374; KEGG: ddf:DEFDS_1109 type IV pilus assembly protein PilB; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Type IV pilus assembly protein PilB; TIGRFAM: ATPase, type IV, pilus assembly, PilB YP_004603445.1 PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB; general secretory pathway protein E; COGs: COG0169 Shikimate 5-dehydrogenase; HAMAP: Shikimate dehydrogenase; InterPro IPR013708:IPR006151:IPR011342; KEGG: ddf:DEFDS_1108 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: Shikimate 5-dehydrogenase; TIGRFAM: Quinate/shikimate 5-dehydrogenase YP_004603446.1 PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; COGs: COG2928 conserved hypothetical protein; InterPro IPR007462; KEGG: ddf:DEFDS_1107 hypothetical protein; PFAM: Protein of unknown function DUF502; SPTR: Putative uncharacterized protein YP_004603447.1 PFAM: Protein of unknown function (DUF502); COGs: COG1584 membrane protein; InterPro IPR000791; KEGG: ddf:DEFDS_0518 hypothetical protein; PFAM: GPR1/FUN34/yaaH; SPTR: Putative uncharacterized protein YP_004603448.1 PFAM: GPR1/FUN34/yaaH family; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR001450:IPR002932; KEGG: ddf:DEFDS_1016 hypothetical protein; PFAM: Glutamate synthase, central-C; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Glutamate synthase (NADPH); SPTR: Putative uncharacterized protein YP_004603449.1 PFAM: Conserved region in glutamate synthase; KEGG: ddf:DEFDS_1015 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603450.1 PFAM: Glutamine amidotransferases class-II; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027; KEGG: dap:Dacet_0101 glucose-inhibited division protein A; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Glutamate synthase (NADPH); SPTR: Glucose-inhibited division protein A YP_004603451.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1796 DNA polymerase IV (family X); InterPro IPR004013:IPR002054:IPR003141; KEGG: ddf:DEFDS_1013 DNA polymerase family X; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase, family X; Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase, family X YP_004603452.1 PFAM: PHP domain; COGs: COG1896 hydrolase of HD superfamily; KEGG: sfu:Sfum_0396 HAD superfamily hydrolase; SPTR: Hydrolase (HAD superfamily) YP_004603453.1 COGs: COG0861 Membrane protein TerC possibly involved in tellurium resistance; InterPro IPR005496; KEGG: azl:AZL_002460 TerC-like membrane protein; PFAM: Integral membrane protein TerC; SPTR: TerC-like membrane protein YP_004603454.1 PFAM: Integral membrane protein TerC family; COGs: COG4663 TRAP-type mannitol/chloroaromatic compound transport system periplasmic component; InterPro IPR018389; KEGG: ant:Arnit_0124 family 7 extracellular solute-binding protein; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Extracellular solute-binding protein, family 7 YP_004603455.1 PFAM: Bacterial extracellular solute-binding protein, family 7; COGs: COG4664 TRAP-type mannitol/chloroaromatic compound transport system large permease component; InterPro IPR010656:IPR004681; KEGG: trap dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit YP_004603456.1 PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG4665 TRAP-type mannitol/chloroaromatic compound transport system small permease component; InterPro IPR007387; KEGG: ant:Arnit_0123 tripartite ATP-independent periplasmic transporter subunit DctQ; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Tripartite ATP-independent periplasmic transporter DctQ component YP_004603457.1 PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG4663 TRAP-type mannitol/chloroaromatic compound transport system periplasmic component; InterPro IPR018389; KEGG: ant:Arnit_0124 family 7 extracellular solute-binding protein; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Extracellular solute-binding protein, family 7 YP_004603458.1 PFAM: Bacterial extracellular solute-binding protein, family 7; InterPro IPR000866; KEGG: cni:Calni_0068 alkyl hydroperoxide reductase/thiol specific antioxidant/mal allergen; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_004603459.1 PFAM: AhpC/TSA family; COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR002912; KEGG: ddf:DEFDS_1490 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; Amino acid-binding ACT; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing protein YP_004603460.1 PFAM: CBS domain; ACT domain; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: cni:Calni_1820 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: Phenylacetate-CoA ligase YP_004603461.1 PFAM: AMP-binding enzyme; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: cni:Calni_1821 amino acid/amide abc transporter ATP-binding protein 2, haat family; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Branched-chain amino acid ABC transporter, ATP-binding protein YP_004603462.1 PFAM: ABC transporter; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: ddf:DEFDS_1493 branched-chain amino acid ABC transporter substrate-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: Branched-chain amino acid ABC transporter, substrate-binding protein YP_004603463.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: ddf:DEFDS_1494 branched-chain amino acid ABC transporter permease; PFAM: Bacterial inner-membrane translocator; SPTR: Branched-chain amino acid ABC transporter, permease YP_004603464.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: cni:Calni_1824 amino acid/amide abc transporter membrane protein 1, haat family; PFAM: Bacterial inner-membrane translocator; SPTR: Amino acid/amide ABC transporter membrane protein 1, HAAT family YP_004603465.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: cni:Calni_1825 amp-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-dependent synthetase and ligase YP_004603466.1 PFAM: AMP-binding enzyme; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: cni:Calni_1826 amino acid/amide abc transporter ATP-binding protein 1, haat family; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family YP_004603467.1 PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR004879; KEGG: ddf:DEFDS_1296 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603468.1 PFAM: Protein of unknown function, DUF255; KEGG: ddf:DEFDS_1290 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603469.1 PFAM: Membrane protein of unknown function (DUF340); COGs: COG2431 membrane protein; InterPro IPR005642; KEGG: ddf:DEFDS_1289 hypothetical protein; PFAM: Protein of unknown function DUF340, prokaryotic membrane; SPTR: Putative uncharacterized protein YP_004603470.1 PFAM: Membrane protein of unknown function (DUF340); COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: ddf:DEFDS_1457 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein YP_004603471.1 PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain; KEGG: dap:Dacet_2935 transcriptional regulator, TraR/DksA family; SPTR: Transcriptional regulator, TraR/DksA family YP_004603472.1 PFAM: Prokaryotic dksA/traR C4-type zinc finger; COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: dap:Dacet_2435 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004603473.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR005892:IPR003439:IPR000644:IPR003593; KEGG: dap:Dacet_2436 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter-like; Cystathionine beta-synthase, core; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; Cystathionine beta-synthase, core; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: Glycine betaine/L-proline transport ATP-binding subunit YP_004603474.1 PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit; COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: dap:Dacet_2437 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004603475.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: dap:Dacet_2438 substrate-binding region of ABC-type glycine betaine transport system; PFAM: ABC-type glycine betaine transport system, substrate-binding region; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; manually curated YP_004603476.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: dal:Dalk_2552 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603477.1 PFAM: Transposase DDE domain; KEGG: pin:Ping_0589 cyclic-di-GMP regulatory protein; SPTR: Regulatory protein for cyclic-di-GMP, EAL/GGDEF domains YP_004603478.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted YP_004603479.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004603480.1 PFAM: EamA-like transporter family; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603481.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); manually curated YP_004603482.1 COGs: COG0268 Ribosomal protein S20; HAMAP: Ribosomal protein S20; InterPro IPR002583; KEGG: ddf:DEFDS_1532 30S ribosomal protein S20; PFAM: Ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: Ribosomal protein S20 YP_004603483.1 PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20; InterPro IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; SPTR: Pilin inverting protein, putative YP_004603484.1 PFAM: Transposase IS116/IS110/IS902 family; InterPro IPR002525; KEGG: tye:THEYE_A1667 pilin inverting protein, putative; PFAM: Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004603485.1 PFAM: Transposase; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603486.1 PFAM: Transposase domain (DUF772); COGs: COG4123 O-methyltransferase; InterPro IPR007848; KEGG: ddf:DEFDS_1884 SAM-dependent methyltransferase; PFAM: Methyltransferase small; SPTR: SAM-dependent methyltransferase YP_004603487.1 PFAM: Methyltransferase small domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 001789; KEGG: ppd:Ppro_2598 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS YP_004603488.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Protein of unknown function (DUF3365); PAS fold; TIGRFAM: PAS domain S-box YP_004603489.1 InterPro IPR007712; KEGG: mrb:Mrub_0782 plasmid stabilization system; PFAM: Plasmid stabilisation system; SPTR: Plasmid stabilization system YP_004603490.1 PFAM: Plasmid stabilisation system protein YP_004603491.1 PFAM: Peptidase family M23; COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: cni:Calni_0279 SNARE associated golgi protein-related protein; PFAM: SNARE associated Golgi protein; SPTR: SNARE associated Golgi protein-related protein YP_004603492.1 PFAM: SNARE associated Golgi protein; COGs: COG0497 ATPase involved in DNA repair; InterPro IPR004604:IPR003395; KEGG: cni:Calni_0278 DNA repair protein RecN; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: DNA repair protein RecN; TIGRFAM: DNA recombination/repair protein RecN YP_004603493.1 PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN; COGs: COG0061 sugar kinase; HAMAP: inorganic polyphosphate/ATP-NAD kinase; InterPro IPR002504; KEGG: ddf:DEFDS_0942 NAD(+) kinase; PFAM: ATP-NAD/AcoX kinase; PRIAM: NAD(+) kinase; SPTR: Probable inorganic polyphosphate/ATP-NAD kinase YP_004603494.1 PFAM: ATP-NAD kinase; COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002942:IPR002877; KEGG: ddf:DEFDS_0943 hemolysin A; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4; SMART: RNA-binding S4; SPTR: Hemolysin A; TIGRFAM: Haemolysin A YP_004603495.1 PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein; COGs: COG1154 Deoxyxylulose-5-phosphate synthase; HAMAP: Deoxyxylulose-5-phosphate synthase; InterPro IPR005477:IPR005475:IPR005476; KEGG: ddf:DEFDS_0944 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: Deoxyxylulose-5-phosphate synthase YP_004603496.1 PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dap:Dacet_1901 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase YP_004603497.1 PFAM: Polyprenyl synthetase; HAMAP: Exonuclease VII, small subunit; InterPro IPR003761; KEGG: ddf:DEFDS_0946 exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; SPTR: Exodeoxyribonuclease 7 small subunit; TIGRFAM: Exonuclease VII, small subunit YP_004603498.1 PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603499.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG2217 Cation transport ATPase; InterProIPR006416:IPR001757:IPR006121:IPR008250:IPR 005834; KEGG: cac:CA_C2241 cation transport P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Cation transport P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter YP_004603500.1 PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: fno:Fnod_0771 regulatory protein ArsR; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Regulatory protein ArsR YP_004603501.1 PFAM: Bacterial regulatory protein, arsR family; manually curated YP_004603502.1 PFAM: ABC transporter; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Probable transposase YP_004603503.1 PFAM: Transposase DDE domain; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603504.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); KEGG: sun:SUN_1938 hypothetical protein; SPTR: Transposase, IS4 family protein YP_004603505.1 manually curated YP_004603506.1 PFAM: Predicted permease; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: ddf:DEFDS_0073 hypothetical protein; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; SPTR: Putative uncharacterized protein YP_004603507.1 PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: ddf:DEFDS_0658 branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Branched-chain amino acid ABC transporter, ATP-binding protein YP_004603508.1 PFAM: ABC transporter; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dat:HRM2_04920 LivG2; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: LivG2 YP_004603509.1 PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: ddf:DEFDS_0656 branched-chain amino acid ABC transporter permease; PFAM: Bacterial inner-membrane translocator; SPTR: Branched-chain amino acid ABC transporter, permease YP_004603510.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: dps:DP2489 high-affinity branched-chain amino acid ABC-transporter, permease protein (BraD); PFAM: Bacterial inner-membrane translocator; SPTR: Probable high-affinity branched-chain amino acid ABC-transporter, permease protein (BraD) YP_004603511.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: ddf:DEFDS_0654 branched-chain amino acid ABC transporter substrate-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: Branched-chain amino acid ABC transporter, substrate-binding protein YP_004603512.1 PFAM: Receptor family ligand binding region; COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); HAMAP: Tryptophan synthase beta chain; InterPro IPR006316:IPR001926; KEGG: cni:Calni_2017 tryptophan synthase, beta chain; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain 1; TIGRFAM: Tryptophan synthase, beta chain-like YP_004603513.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: ddf:DEFDS_1431 hypothetical protein; PFAM: Protein of unknown function DUF208; SPTR: Putative uncharacterized protein YP_004603514.1 PFAM: Uncharacterized BCR, COG1636; KEGG: cni:Calni_0030 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603515.1 PFAM: Protein of unknown function (DUF2905); COGs: COG1278 Cold shock protein; InterPro IPR002059:IPR011129; KEGG: ddf:DEFDS_1433 cold shock protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Cold shock protein YP_004603516.1 PFAM: 'Cold-shock' DNA-binding domain; InterPro IPR003448; KEGG: cni:Calni_1063 molybdopterin biosynthesis protein MoaE; PFAM: Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin biosynthesis protein MoaE YP_004603517.1 PFAM: MoaE protein; COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931; KEGG: cni:Calni_0550 transglutaminase domain-containing protein; PFAM: Transglutaminase-like; SMART: Transglutaminase-like; SPTR: Transglutaminase domain-containing protein YP_004603518.1 PFAM: Transglutaminase-like superfamily; Domain of unknown function (DUF3488); manually curated YP_004603519.1 PFAM: ATPase family associated with various cellular activities (AAA); COGs: COG4327 membrane protein; InterPro IPR019886; KEGG: ddf:DEFDS_1575 hypothetical protein; SPTR: Putative solute symporter protein; TIGRFAM: Probable solute:sodium symporter, small subunit YP_004603520.1 TIGRFAM: putative solute:sodium symporter small subunit; COGs: COG4147 symporter; InterPro IPR019899:IPR001734; KEGG: ddf:DEFDS_1574 solute:sodium symporter; PFAM: Sodium/solute symporter; SPTR: Solute:sodium symporter; TIGRFAM: Sodium/solute symporter, VC2705 subfamily YP_004603521.1 PFAM: Sodium:solute symporter family; TIGRFAM: probable sodium:solute symporter, VC_2705 subfamily; KEGG: ddf:DEFDS_1573 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603522.1 COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000595:IPR000644:IPR005105:IPR018821; KEGG: ddf:DEFDS_1572 cyclic nucleotide binding protein; PFAM: Protein of unknown function DUF294, nucleotidyltransferase putative; Cystathionine beta-synthase, core; Cyclic nucleotide-binding; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: Cystathionine beta-synthase, core; Cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding protein YP_004603523.1 PFAM: Putative nucleotidyltransferase substrate binding domain; CBS domain; Cyclic nucleotide-binding domain; Putative nucleotidyltransferase DUF294; COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015413:IPR013155; KEGG: ddf:DEFDS_0790 leucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Valine--tRNA ligase; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial YP_004603524.1 PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; KEGG: cni:Calni_0470 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603525.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372; KEGG: cni:Calni_0471 DNA polymerase III delta; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III delta YP_004603526.1 PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1489 DNA-binding protein stimulates sugar fermentation; HAMAP: Sugar fermentation stimulation protein; InterPro IPR005224; KEGG: cni:Calni_0493 sugar fermentation stimulation protein; PFAM: Sugar fermentation stimulation protein; SPTR: Sugar fermentation stimulation protein; TIGRFAM: Sugar fermentation stimulation protein YP_004603527.1 PFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: ddf:DEFDS_1602 hypothetical protein; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Putative uncharacterized protein YP_004603528.1 PFAM: Transglycosylase SLT domain; InterPro IPR000182; KEGG: dae:Dtox_2879 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004603529.1 PFAM: Acetyltransferase (GNAT) family; COGs: COG3044 ATPase of the ABC class; InterPro IPR019195; KEGG: tit:Thit_0992 ABC transporter, ATPase, predicted; PFAM: ABC transporter, ATPase, predicted; SPTR: Putative uncharacterized protein YP_004603530.1 PFAM: Predicted ATPase of the ABC class; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638:IPR001320; KEGG: drt:Dret_1093 extracellular solute-binding protein family 3; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; Ionotropic glutamate receptor; SPTR: Extracellular solute-binding protein family 3 YP_004603531.1 PFAM: Bacterial extracellular solute-binding proteins, family 3; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: dvm:DvMF_1919 polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_004603532.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dsa:Desal_2287 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related YP_004603533.1 PFAM: ABC transporter; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192; KEGG: dap:Dacet_2177 pyruvate phosphate dikinase PEP/pyruvate-binding protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding protein YP_004603534.1 PFAM: Pyruvate phosphate dikinase, PEP/pyruvate binding domain; COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: dap:Dacet_2178 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glu/Leu/Phe/Val dehydrogenase YP_004603535.1 PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603536.1 COGs: COG3332 conserved hypothetical protein; InterPro IPR008551; KEGG: swo:Swol_2245 hypothetical protein; PFAM: Protein of unknown function DUF833; SPTR: Putative uncharacterized protein YP_004603537.1 PFAM: Protein of unknown function (DUF833); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: sfu:Sfum_1309 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Lactaldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase (NAD(+)) YP_004603538.1 PFAM: Aldehyde dehydrogenase family; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR004017; KEGG: cni:Calni_1838 fad linked oxidase domain protein; PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; Cysteine-rich region, CCG; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: FAD linked oxidase domain protein YP_004603539.1 PFAM: Cysteine-rich domain; FAD binding domain; FAD linked oxidases, C-terminal domain; KEGG: ddf:DEFDS_1393 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603540.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: tRNA-i(6)A37 modification enzyme MiaB; InterProIPR005839:IPR006463:IPR013848:IPR007197:IPR 002792:IPR006638; KEGG: ddf:DEFDS_1391 tRNA-i(6)A37 thiotransferase enzyme; PFAM: Methylthiotransferase, N-terminal; Radical SAM; Deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: tRNA-i(6)A37 thiotransferase enzyme; TIGRFAM: Methylthiotransferase; tRNA-i(6)A37 modification enzyme MiaB YP_004603541.1 PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; radical SAM methylthiotransferase, MiaB/RimO family; COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: ddf:DEFDS_1390 hypothetical protein; PFAM: Protein of unknown function DUF151; SPTR: Putative uncharacterized protein YP_004603542.1 PFAM: Uncharacterised ACR, COG1259; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: ddf:DEFDS_1389 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: Putative uncharacterized protein YP_004603543.1 PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; COGs: COG4717 conserved hypothetical protein; KEGG: mbu:Mbur_1259 hypothetical protein; SPTR: ATPase domain-like membrane protein YP_004603544.1 COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: cni:Calni_1842 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_004603545.1 PFAM: Carbon-nitrogen hydrolase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099; KEGG: aca:ACP_1229 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Pyridine nucleotide-disulphide oxidoreductase YP_004603546.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: gme:Gmet_0123 flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; PRIAM: 2,4-dienoyl-CoA reductase (NADPH); SPTR: Flavin oxidoreductase/NADH oxidase YP_004603547.1 PFAM: NADH:flavin oxidoreductase / NADH oxidase family; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: ddf:DEFDS_0678 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Isochorismatase hydrolase YP_004603548.1 PFAM: Isochorismatase family; COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR004572:IPR002937; KEGG: ddf:DEFDS_1356 protoporphyrinogen oxidase; PFAM: Amine oxidase; PRIAM: Protoporphyrinogen oxidase; SPTR: Protoporphyrinogen oxidase; TIGRFAM: Protoporphyrinogen oxidase YP_004603549.1 PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase; InterPro IPR003790; KEGG: ddf:DEFDS_1357 hypothetical protein; PFAM: Protein of unknown function DUF187; SPTR: Putative uncharacterized protein YP_004603550.1 PFAM: Uncharacterised BCR, COG1649; InterPro IPR007730; KEGG: ddf:DEFDS_1358 hypothetical protein; PFAM: Sporulation/cell division region, bacteria; SPTR: Putative uncharacterized protein YP_004603551.1 PFAM: Sporulation related domain; COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR005148:IPR015945:IPR008909; KEGG: cni:Calni_1453 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; Arginyl tRNA synthetase, class Ic, N-terminal; DALR anticodon binding; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic YP_004603552.1 PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; COGs: COG1280 Putative threonine efflux protein; InterPro IPR001123; KEGG: hel:HELO_3429 hypothetical protein; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Putative uncharacterized protein YP_004603553.1 PFAM: LysE type translocator; TIGRFAM: The Resistance to Homoserine/Threonine (RhtB) Family protein; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603554.1 PFAM: Transposase domain (DUF772) YP_004603555.1 KEGG: cni:Calni_1608 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603556.1 InterPro IPR010173:IPR005537; KEGG: cni:Calni_1609 crispr-associated RAMP protein, csm5 family; PFAM: Protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, Csm5 family; TIGRFAM: CRISPR-associated protein, TM1807 YP_004603557.1 PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm5; InterPro IPR005537; KEGG: cni:Calni_1610 crispr-associated protein, csm4 family; PFAM: Protein of unknown function DUF324; SPTR: CRISPR-associated protein, Csm4 family YP_004603558.1 TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm4; COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR013412:IPR005537; KEGG: cni:Calni_1611 crispr-associated protein, csm3 family; PFAM: Protein of unknown function DUF324; SPTR: CRISPR-associated protein, Csm3 family; TIGRFAM: CRISPR-associated RAMP Csm3 YP_004603559.1 PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm3; InterPro IPR010149; KEGG: cni:Calni_1612 crispr-associated protein, csm2 family; PFAM: CRISPR-associated protein, TM1810 C-terminal; SPTR: CRISPR-associated protein, Csm2 family; TIGRFAM: CRISPR-associated protein, TM1810 C-terminal YP_004603560.1 PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR type III-A/MTUBE-associated protein Csm2; This gene is disrupted by insertion of repetitive element; manually curated YP_004603561.1 PFAM: Transposase domain (DUF772); InterPro IPR015093; KEGG: cni:Calni_1614 hypothetical protein; PFAM: Protein of unknown function DUF1887; SPTR: Putative uncharacterized protein YP_004603562.1 PFAM: Domain of unknown function (DUF1887); KEGG: cni:Calni_1615 crispr-associated protein cas6; SPTR: CRISPR-associated protein Cas6 YP_004603563.1 PFAM: Uncharacterized conserved protein (DUF2276); InterPro IPR002059; KEGG: cni:Calni_1600 hypothetical protein; PFAM: Cold-shock protein, DNA-binding; SPTR: Putative uncharacterized protein YP_004603564.1 PFAM: 'Cold-shock' DNA-binding domain; COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR003799; KEGG: cni:Calni_1597 crispr-associated protein cas2; SPTR: CRISPR-associated protein Cas2; TIGRFAM: Protein of unknown function DUF196 YP_004603565.1 PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2; COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729; KEGG: cni:Calni_1599 crispr-associated protein cas1; PFAM: CRISPR-associated protein Cas1; SPTR: CRISPR-associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1 YP_004603566.1 PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1; COGs: COG4951 conserved hypothetical protein; KEGG: cni:Calni_1598 DNA primase small subunit; SPTR: DNA primase small subunit YP_004603567.1 KEGG: cni:Calni_1607 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603568.1 KEGG: cni:Calni_1606 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603569.1 KEGG: cni:Calni_1605 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603570.1 KEGG: cni:Calni_1604 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603571.1 InterPro IPR000620; KEGG: cni:Calni_1114 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein YP_004603572.1 PFAM: EamA-like transporter family; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR005116:IPR003593; KEGG: dsa:Desal_2874 ABC transporter related; PFAM: ABC transporter-like; Transport-associated OB, type 1; PRIAM: Molybdate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative abc-transport system ATP-binding protein YP_004603573.1 PFAM: ABC transporter; TOBE domain; TIGRFAM: molybdenum-pterin binding domain; COGs: COG4662 ABC-type tungstate transport system periplasmic component; InterPro IPR000515; KEGG: dat:HRM2_17610 predicted ABC-type molybdate/tungstate transporter, permease component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Predicted ABC-type molybdate/tungstate transporter, permease component YP_004603574.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG2998 ABC-type tungstate transport system permease component; KEGG: dat:HRM2_17620 predicted ABC-type molybdate/tungstate transporter, periplasmic substrate binding protein; SPTR: Putative tungstate ABC transporter, tungstate-binding protein YP_004603575.1 COGs: COG1910 Periplasmic molybdate-binding protein/domain; InterPro IPR010093; KEGG: sat:SYN_00844 molybdate-binding protein domain; SPTR: Molybdate-binding protein domain; TIGRFAM: Excisionase/Xis, DNA-binding YP_004603576.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: ddf:DEFDS_1360 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603577.1 KEGG: ddf:DEFDS_1361 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603578.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789; KEGG: gur:Gura_4030 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein YP_004603579.1 PFAM: Response regulator receiver domain; KEGG: cni:Calni_0969 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603580.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR003439:IPR003593; KEGG: cni:Calni_0970 sigma 54 interacting domain protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Sigma 54 interacting domain protein YP_004603581.1 PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: cni:Calni_0971 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein YP_004603582.1 PFAM: Predicted permease; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: ddf:DEFDS_1364 hypothetical protein; PFAM: Peptidase M23; SPTR: Putative uncharacterized protein YP_004603583.1 PFAM: Peptidase family M23; COGs: COG0793 Periplasmic protease; InterPro IPR004447:IPR001478:IPR005151; KEGG: ddf:DEFDS_1365 carboxyl-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; PRIAM: C-terminal processing peptidase; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Carboxyl-terminal protease; TIGRFAM: Peptidase S41A, C-terminal protease YP_004603584.1 PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); COGs: COG2861 conserved hypothetical protein; InterPro IPR006837; KEGG: cni:Calni_0974 hypothetical protein; PFAM: Protein of unknown function DUF610, YibQ; SPTR: Putative uncharacterized protein YP_004603585.1 PFAM: Divergent polysaccharide deacetylase; COGs: COG0533 Metal-dependent protease with possible chaperone activity; HAMAP: O-sialoglycoprotein endopeptidase; InterPro IPR017861:IPR000905; KEGG: dap:Dacet_1813 metalloendopeptidase, glycoprotease family; PFAM: Peptidase M22, glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: Probable O-sialoglycoprotein endopeptidase; TIGRFAM: putative glycoprotease GCP; Peptidase M22, glycoprotease, subgroup YP_004603586.1 PFAM: Glycoprotease family; TIGRFAM: putative glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family; COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269; KEGG: ddf:DEFDS_1368 tRNA-dihydrouridine synthase; PFAM: tRNA-dihydrouridine synthase; SPTR: tRNA-dihydrouridine synthase YP_004603587.1 PFAM: Dihydrouridine synthase (Dus); TIGRFAM: putative TIM-barrel protein, nifR3 family; COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: ddf:DEFDS_0624 fibronectin/fibrinogen-binding protein; PFAM: Protein of unknown function DUF814; Fibronectin-binding A, N-terminal; SPTR: Fibronectin/fibrinogen-binding protein YP_004603588.1 PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR001482:IPR003593; KEGG: cni:Calni_1207 pilus retraction atpase PilT; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Pilus retraction ATPase PilT; TIGRFAM: Pilus retraction protein PilT YP_004603589.1 PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT; InterPro IPR007831; KEGG: ddf:DEFDS_0626 hypothetical protein; PFAM: General secretory system II, protein E, N-terminal; SPTR: Putative uncharacterized protein YP_004603590.1 PFAM: GSPII_E N-terminal domain; InterPro IPR001440:IPR019734; KEGG: ddf:DEFDS_0627 hypothetical protein; PFAM: Tetratricopeptide TPR-1; SPTR: Putative uncharacterized protein YP_004603591.1 KEGG: ddf:DEFDS_1231 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603592.1 PFAM: Thioesterase superfamily; KEGG: ddf:DEFDS_0677 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004603593.1 KEGG: geo:Geob_1347 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603595.1 KEGG: pop:POPTR_597343 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603596.1 InterPro IPR002559; KEGG: sun:SUN_1976 transposase; PFAM: Transposase, IS4-like; SPTR: Probable transposase YP_004603597.1 PFAM: Transposase DDE domain; KEGG: dap:Dacet_1791 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603598.1 KEGG: dap:Dacet_1790 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603599.1 Bacterial RNase P class A as predicted by Rfam (RF00010), score 305.73 YP_004603600.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: cni:Calni_0544 hypothetical protein; PFAM: Secretion protein HlyD; SPTR: Putative uncharacterized protein YP_004603601.1 PFAM: HlyD family secretion protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593; KEGG: cni:Calni_0543 abc transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004603602.1 PFAM: ABC transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: cni:Calni_0542 abc-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter YP_004603603.1 PFAM: ABC-2 type transporter; InterPro IPR013525; KEGG: cni:Calni_0541 abc-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter YP_004603604.1 PFAM: ABC-2 type transporter; COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: cni:Calni_1365 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase catalytic YP_004603605.1 PFAM: Transglycosylase SLT domain; COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR006054:IPR013520:IPR006055; KEGG: dap:Dacet_1757 DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease; SPTR: DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit YP_004603606.1 PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: ddf:DEFDS_1380 hypothetical protein; PFAM: Iojap-related protein; SPTR: Putative uncharacterized protein; TIGRFAM: Iojap-related protein YP_004603607.1 PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein; COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; HAMAP: nicotinate-nucleotide adenylyltransferase; InterPro IPR004821:IPR005248:IPR004820; KEGG: ddf:DEFDS_1381 nicotinate-nucleotide adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: Probable nicotinate-nucleotide adenylyltransferase; Cytidyltransferase-related YP_004603608.1 PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain; COGs: COG0014 Gamma-glutamyl phosphate reductase; HAMAP: Glutamate-5-semialdehyde dehydrogenase; InterPro IPR000965:IPR012134; KEGG: ddf:DEFDS_1382 glutamate-5-semialdehyde dehydrogenase; PRIAM: Glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: Gamma-glutamyl phosphate reductase GPR YP_004603609.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase; COGs: COG0263 Glutamate 5-kinase; HAMAP: Glutamate 5-kinase; InterPro IPR005715:IPR001048:IPR002478; KEGG: ddf:DEFDS_1383 glutamate 5-kinase; PFAM: Aspartate/glutamate/uridylate kinase; Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: Glutamate 5-kinase; TIGRFAM: Glutamate 5-kinase, ProB-related YP_004603610.1 PFAM: Amino acid kinase family; PUA domain; TIGRFAM: glutamate 5-kinase YP_004603611.1 COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: cni:Calni_0781 had-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3 YP_004603612.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; 2-phosphoglycolate phosphatase, prokaryotic; KEGG: tye:THEYE_A1944 lipoprotein, putative; SPTR: Putative uncharacterized protein YP_004603613.1 PFAM: Protein of unknown function (DUF3617); COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603614.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR013655:IPR013767:IPR003594:IPR 001789:IPR001610; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold; PAS fold-3; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; PAS; PAC motif; Signal transduction response regulator, receiver region; SPTR: Multi-sensor hybrid histidine kinase; TIGRFAM: PAS YP_004603615.1 PFAM: ABC transporter substrate binding protein; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: nis:NIS_1506 ribosomal large subunit pseudouridine synthase D; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase YP_004603616.1 PFAM: RNA pseudouridylate synthase YP_004603617.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004603618.1 COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: gsu:GSU0910 aldehyde:ferredoxin oxidoreductase, tungsten-containing; PFAM: Aldehyde ferredoxin oxidoreductase, C-terminal; Aldehyde ferredoxin oxidoreductase, N-terminal; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal; SPTR: Aldehyde:ferredoxin oxidoreductase, tungsten-containing YP_004603619.1 PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450; KEGG: ddf:DEFDS_0246 4Fe-4S ferredoxin; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin YP_004603620.1 PFAM: 4Fe-4S binding domain; InterPro IPR003749; KEGG: ddf:DEFDS_1122 molybdenum cofactor biosynthesis protein D; PFAM: ThiamineS; SPTR: Molybdenum cofactor biosynthesis protein D YP_004603621.1 PFAM: ThiS family; KEGG: dap:Dacet_0430 integral membrane sensor signal transduction histidine kinase; SPTR: Integral membrane sensor signal transduction histidine kinase YP_004603622.1 InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603623.1 PFAM: Transposase DDE domain; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: cni:Calni_0441 cobalamin (vitamin b12) biosynthesis CbiM protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein YP_004603624.1 PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM; COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: cni:Calni_0440 cobalt transport protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport protein YP_004603625.1 PFAM: Cobalt transport protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: cni:Calni_0439 abc transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004603626.1 PFAM: ABC transporter; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006388:IPR006328:IPR005834; KEGG: slt:Slit_1336 haloacid dehalogenase, type II; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: (S)-2-haloacid dehalogenase; SPTR: Haloacid dehalogenase, type II; TIGRFAM: Haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 YP_004603627.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; 2-haloalkanoic acid dehalogenase, type II; KEGG: cyp:PCC8801_3050 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated YP_004603628.1 COGs: COG5421 Transposase; InterPro IPR002559; KEGG: dal:Dalk_2552 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603629.1 PFAM: Transposase DDE domain; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: ddf:DEFDS_1789 MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial YP_004603630.1 PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603631.1 PFAM: Transposase DDE domain; KEGG: ddf:DEFDS_1790 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603632.1 COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175; KEGG: cni:Calni_0563 endoribonuclease L-psp; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; TIGRFAM: YjgF-like protein YP_004603633.1 PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative; KEGG: ddf:DEFDS_0649 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603634.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ddf:DEFDS_0648 octaprenyl-diphosphate synthase; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: Octaprenyl-diphosphate synthase YP_004603635.1 PFAM: Polyprenyl synthetase; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197; KEGG: ddf:DEFDS_0647 pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM; SPTR: Pyruvate-formate lyase-activating enzyme YP_004603636.1 PFAM: Radical SAM superfamily; COGs: COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: ddf:DEFDS_0646 thiamine biosynthesis lipoprotein ApbE; PFAM: ApbE-like lipoprotein; SPTR: Thiamine biosynthesis lipoprotein ApbE YP_004603637.1 PFAM: ApbE family; InterPro IPR010739; KEGG: ddf:DEFDS_0645 hypothetical protein; PFAM: Protein of unknown function DUF1312; SPTR: Putative uncharacterized protein YP_004603638.1 PFAM: Protein of unknown function (DUF1312); COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: ddf:DEFDS_0644 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Putative uncharacterized protein YP_004603639.1 PFAM: Heptaprenyl diphosphate synthase component I; COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; HAMAP: Maf-like protein; InterPro IPR003697; KEGG: cni:Calni_0556 maf protein; PFAM: Maf-like protein; SPTR: Maf-like protein Calni_0556; TIGRFAM: Maf-like protein YP_004603640.1 PFAM: Maf-like protein; TIGRFAM: MAF protein; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: ddf:DEFDS_0642 long-chain fatty-acid-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Long-chain fatty-acid-CoA ligase YP_004603641.1 PFAM: AMP-binding enzyme; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR013563:IPR003593; KEGG: ddf:DEFDS_0839 phosphate-transporting ATPase; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Phosphate-transporting ATPase YP_004603642.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR002308:IPR015803:IPR015273; KEGG: ddf:DEFDS_0838 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia YP_004603643.1 PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: cni:Calni_0408 nad-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucuronate 4-epimerase; SPTR: NAD-dependent epimerase/dehydratase YP_004603644.1 PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: cni:Calni_0212 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_004603645.1 PFAM: Carbon-nitrogen hydrolase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: cni:Calni_0213 acetyl-CoA hydrolase; PFAM: Acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: Acetyl-CoA hydrolase YP_004603646.1 PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; TIGRFAM: succinate CoA transferases; InterPro IPR000845; KEGG: dap:Dacet_1934 purine or other phosphorylase family 1; PFAM: Nucleoside phosphorylase; SPTR: Purine or other phosphorylase family 1 YP_004603647.1 PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase; COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR004620:IPR003171; KEGG: ddf:DEFDS_1143 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; PRIAM: Methylenetetrahydrofolate reductase (NAD(P)H); SPTR: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase YP_004603648.1 PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: dap:Dacet_1180 ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family YP_004603649.1 PFAM: Ferric uptake regulator family; COGs: COG0753 Catalase; InterPro IPR018028:IPR010582; KEGG: nhl:Nhal_1142 catalase; PFAM: Catalase related subgroup; Catalase-related immune responsive; PRIAM: Catalase; SPTR: Catalase YP_004603650.1 PFAM: Catalase; Catalase-related immune-responsive; COGs: COG0506 Proline dehydrogenase; InterPro IPR002872; KEGG: ddf:DEFDS_1068 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase YP_004603651.1 PFAM: Proline dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005931:IPR015590; KEGG: cni:Calni_0885 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: 1-pyrroline-5-carboxylate dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 1 YP_004603652.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; HAMAP: 5-methylthioadenosine/S-adenosylhomocysteine deaminase; InterPro IPR006680; KEGG: ddf:DEFDS_1223 N-ethylammeline chlorohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: 5-methylthioadenosine/S-adenosylhomocysteine deaminase YP_004603653.1 PFAM: Amidohydrolase family; InterPro IPR008815; KEGG: sun:SUN_0718 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein YP_004603654.1 PFAM: S23 ribosomal protein; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR019468; KEGG: ddf:DEFDS_1224 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase, C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase YP_004603655.1 PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: ddf:DEFDS_0484 ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase B; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B YP_004603656.1 PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family; COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: ddf:DEFDS_0485 glycine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase YP_004603657.1 PFAM: Serine hydroxymethyltransferase; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: ddf:DEFDS_0486 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: CMP/dCMP deaminase, zinc-binding protein YP_004603658.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; HAMAP: Electron transport complex protein rnfC; InterPro IPR010208:IPR011538:IPR019554:IPR001450; KEGG: cni:Calni_0590 electron transport complex, rnfabcdge type, C subunit; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Electron transport complex, RnfABCDGE type, C subunit; TIGRFAM: Electron transport complex, RnfC YP_004603659.1 PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR011303:IPR004338; KEGG: ddf:DEFDS_0488 electron transport complex protein RnfD; PFAM: NADH-quinone reductase NQR2/RnfD; SPTR: Electron transport complex protein RnfD; TIGRFAM: Electron transport complex, RnfD YP_004603660.1 PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; COGs: COG4659 NADH:ubiquinone oxidoreductase subunit RnfG; InterPro IPR010209:IPR007329; KEGG: ddf:DEFDS_0489 electron transport complex protein RnfG; PFAM: FMN-binding; SPTR: Electron transport complex protein RnfG; TIGRFAM: Electron transport complex, RnfG YP_004603661.1 PFAM: FMN-binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; InterPro IPR010968:IPR003667; KEGG: ddf:DEFDS_0490 electron transport complex protein RnfE; PFAM: Electron transport complex, Rnf/Nqr; SPTR: Electron transport complex protein RnfE; TIGRFAM: Electron transport complex, RnfE YP_004603662.1 PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; COGs: COG4657 NADH:ubiquinone oxidoreductase subunit RnfA; InterPro IPR011293:IPR003667; KEGG: ddf:DEFDS_0491 electron transport complex protein RnfA; PFAM: Electron transport complex, Rnf/Nqr; SPTR: Electron transport complex protein RnfA; TIGRFAM: Electron transport complex, RnfA YP_004603663.1 PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; COGs: COG2878 NADH:ubiquinone oxidoreductase subunit RnfB; InterPro IPR010207:IPR007202:IPR001450; KEGG: ddf:DEFDS_0492 electron transport complex protein RnfB; PFAM: Putative Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Electron transport complex protein RnfB; TIGRFAM: Electron transport complex, RnfB YP_004603664.1 PFAM: Putative Fe-S cluster; 4Fe-4S binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: ddf:DEFDS_0493 acetoin utilization protein AcuC; PFAM: Histone deacetylase superfamily; SPTR: Acetoin utilization protein AcuC YP_004603665.1 PFAM: Histone deacetylase domain; COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004603666.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: ddf:DEFDS_1074 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+); PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP+) YP_004603667.1 PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase; COGs: COG2165 Type II secretory pathway pseudopilin PulG; InterPro IPR012902:IPR010054:IPR013545; KEGG: ddf:DEFDS_1311 general secretion pathway protein G; PFAM: Type II secretion system protein G; Prepilin-type cleavage/methylation, N-terminal; SPTR: General secretion pathway protein G; TIGRFAM: General secretion pathway protein G; Prepilin-type cleavage/methylation, N-terminal YP_004603668.1 PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain; InterPro IPR012902; KEGG: dap:Dacet_0486 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603669.1 TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; InterPro IPR012902; KEGG: ddf:DEFDS_1313 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603670.1 PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; InterPro IPR012902; KEGG: dap:Dacet_0484 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603671.1 TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; KEGG: dap:Dacet_0483 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603672.1 PFAM: General secretion pathway protein K; KEGG: ddf:DEFDS_1316 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603673.1 KEGG: ddf:DEFDS_1317 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603674.1 KEGG: ddf:DEFDS_1318 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603675.1 KEGG: ddf:DEFDS_1319 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603676.1 COGs: COG1971 membrane protein; HAMAP: UPF0059 membrane protein yebN; InterPro IPR003810; KEGG: cni:Calni_1186 hypothetical protein; PFAM: Protein of unknown function DUF204; SPTR: UPF0059 membrane protein Calni_1186 YP_004603677.1 PFAM: Domain of unknown function DUF; COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: ddf:DEFDS_1279 hypothetical protein; PFAM: Protein of unknown function DUF178; SPTR: Putative uncharacterized protein YP_004603678.1 PFAM: Putative periplasminc binding protein (DUF178); COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: ddf:DEFDS_1278 mechanosensitive ion channel, MscS family; PFAM: Mechanosensitive ion channel MscS; SPTR: Mechanosensitive ion channel, MscS family YP_004603679.1 PFAM: Mechanosensitive ion channel; KEGG: ddf:DEFDS_1277 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603680.1 PFAM: Stringent starvation protein B; InterPro IPR018392:IPR002482; KEGG: ddf:DEFDS_0822 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Putative uncharacterized protein YP_004603681.1 PFAM: LysM domain; COGs: COG0173 Aspartyl-tRNA synthetase; InterPro IPR004524:IPR004365:IPR004364:IPR004115; KEGG: cni:Calni_0871 aspartyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; GAD domain; PRIAM: Aspartate--tRNA ligase; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type YP_004603682.1 PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type; COGs: COG0124 Histidyl-tRNA synthetase; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR015807:IPR002314:IPR004154; KEGG: ddf:DEFDS_1553 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup YP_004603683.1 PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; COGs: COG1661 DNA-binding protein with PD1-like DNA-binding motif; InterPro IPR005175; KEGG: ddf:DEFDS_1554 hypothetical protein; PFAM: Protein of unknown function DUF296; SPTR: Putative uncharacterized protein YP_004603684.1 PFAM: Domain of unknown function (DUF296); COGs: COG1102 Cytidylate kinase; KEGG: cni:Calni_0873 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603685.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dap:Dacet_1438 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_004603686.1 PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099; KEGG: dap:Dacet_1440 pyridine nucleotide-disulfide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Pyridine nucleotide-disulfide oxidoreductase dimerization region YP_004603687.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; COGs: COG0192 S-adenosylmethionine synthetase; HAMAP: S-adenosylmethionine synthase; InterPro IPR002133; KEGG: ddf:DEFDS_1515 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase YP_004603688.1 PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; KEGG: ddf:DEFDS_1516 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603689.1 COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: cni:Calni_0878 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein-alanine acetyltransferase; TIGRFAM: Ribosomal-protein-alanine acetyltransferase YP_004603690.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dap:Dacet_1445 peptidase M22 glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22 glycoprotease; TIGRFAM: universal protein YeaZ YP_004603691.1 PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG0756 dUTPase; HAMAP: Deoxyuridine 5'-triphosphate nucleotidohydrolase; InterPro IPR008181:IPR008180; KEGG: cni:Calni_0915 deoxyuridine 5'-triphosphate nucleotidohydrolase; PFAM: DeoxyUTP pyrophosphatase domain; PRIAM: dUTP diphosphatase; SPTR: Deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: DeoxyUTP pyrophosphatase domain, subfamily 1 YP_004603692.1 PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); COGs: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); HAMAP: Polyribonucleotide nucleotidyltransferase; InterProIPR012162:IPR001247:IPR015847:IPR015848:IPR 018111:IPR003029:IPR004087; KEGG: cni:Calni_1295 polyribonucleotide nucleotidyltransferase; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; K Homology, type 1, subgroup; Ribosomal protein S1, RNA binding domain; PRIAM: Polyribonucleotide nucleotidyltransferase; SPTR: Polyribonucleotide nucleotidyltransferase; TIGRFAM: Polyribonucleotide nucleotidyltransferase YP_004603693.1 PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; Polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase; COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR005290:IPR000589; KEGG: ddf:DEFDS_1521 30S ribosomal protein S15; PFAM: Ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: Ribosomal protein S15, bacterial-type YP_004603694.1 PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle; COGs: COG0130 Pseudouridine synthase; HAMAP: tRNA pseudouridine synthase B; InterPro IPR014780:IPR002501; KEGG: ddf:DEFDS_1522 tRNA pseudouridine synthase B; PFAM: Pseudouridine synthase II, TruB, N-terminal; SPTR: tRNA pseudouridine synthase B; TIGRFAM: Pseudouridine synthase II, TruB, N-terminal, bacterial-type YP_004603695.1 PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase; COGs: COG0858 Ribosome-binding factor A; HAMAP: Ribosome-binding factor A; InterPro IPR000238; KEGG: cni:Calni_1298 ribosome-binding factor A; PFAM: Ribosome-binding factor A; SPTR: Ribosome-binding factor A; TIGRFAM: Ribosome-binding factor A YP_004603696.1 PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; COGs: COG1550 conserved hypothetical protein; InterPro IPR007546; KEGG: ddf:DEFDS_1524 hypothetical protein; PFAM: Protein of unknown function DUF503; SPTR: Putative uncharacterized protein YP_004603697.1 PFAM: Protein of unknown function (DUF503); COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterProIPR000178:IPR005225:IPR006847:IPR000795:IPR 004161; KEGG: ddf:DEFDS_1525 translation initiation factor IF-2; PFAM: Protein synthesis factor, GTP-binding; Translation initiation factor IF-2, N-terminal; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Translation initiation factor IF-2; TIGRFAM: Initiation factor 2; Small GTP-binding protein YP_004603698.1 PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2; InterPro IPR007393; KEGG: ddf:DEFDS_1526 hypothetical protein; PFAM: Protein of unknown function DUF448; SPTR: Putative uncharacterized protein; manually curated YP_004603699.1 PFAM: Protein of unknown function (DUF448); COGs: COG0195 Transcription elongation factor; InterPro IPR010213:IPR013735:IPR003029:IPR004087; KEGG: ddf:DEFDS_1527 N utilization substance protein A; PFAM: Transcription factor NusA, N-terminal; Ribosomal protein S1, RNA binding domain; SPTR: N utilization substance protein A; TIGRFAM: Transcription termination factor NusA YP_004603700.1 PFAM: NusA N-terminal domain; S1 RNA binding domain; TIGRFAM: transcription termination factor NusA; HAMAP: Uncharacterised protein family UPF0090, bacteria; InterPro IPR003728:IPR020790; KEGG: ddf:DEFDS_1528 hypothetical protein; PFAM: Uncharacterised protein family UPF0090; SPTR: Ribosome maturation factor rimP YP_004603701.1 PFAM: Uncharacterised BCR, YhbC family COG0779; KEGG: cni:Calni_0995 lipoprotein; SPTR: Putative lipoprotein YP_004603702.1 KEGG: cni:Calni_1389 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603703.1 KEGG: cni:Calni_1388 lipoprotein; SPTR: Putative lipoprotein YP_004603704.1 COGs: COG0158 Fructose-1 6-bisphosphatase; HAMAP: Fructose-1,6-bisphosphatase; InterPro IPR000146; KEGG: ddf:DEFDS_1408 fructose-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 1 YP_004603705.1 PFAM: Fructose-1-6-bisphosphatase; COGs: COG0648 Endonuclease IV; HAMAP: Endodeoxyribonuclease IV; InterPro IPR001719:IPR012307; KEGG: ddf:DEFDS_1407 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; PRIAM: Deoxyribonuclease IV (phage-T(4)-induced); SMART: Endodeoxyribonuclease IV; SPTR: Probable endonuclease 4; TIGRFAM: Endodeoxyribonuclease IV YP_004603706.1 PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1); COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: ddf:DEFDS_1406 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Isochorismatase hydrolase YP_004603707.1 PFAM: Isochorismatase family; COGs: COG2187 conserved hypothetical protein; KEGG: ddf:DEFDS_1405 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603708.1 COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: ddf:DEFDS_1404 ribonuclease Z; SPTR: Ribonuclease Z YP_004603709.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR001160:IPR002933:IPR011650; KEGG: mac:MA2653 aminoacyl-histidine dipeptidase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Xaa-His dipeptidase; SPTR: Aminoacyl-histidine dipeptidase; TIGRFAM: Peptidase M20C, Xaa-His dipeptidase YP_004603710.1 PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: aminoacyl-histidine dipeptidase; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ddf:DEFDS_1576 heat shock protein Hsp20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20 YP_004603711.1 PFAM: Hsp20/alpha crystallin family; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: ddf:DEFDS_0515 cardiolipin synthetase; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase; SPTR: Cardiolipin synthetase YP_004603712.1 PFAM: Phospholipase D Active site motif; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR005911:IPR007197:IPR006638; KEGG: ddf:DEFDS_0514 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01212 YP_004603713.1 PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family; COGs: COG1565 conserved hypothetical protein; InterPro IPR003788; KEGG: ddf:DEFDS_1262 hypothetical protein; PFAM: Protein of unknown function DUF185; SPTR: Putative uncharacterized protein YP_004603714.1 PFAM: Uncharacterized ACR, COG1565; KEGG: ddf:DEFDS_1263 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603715.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: ddf:DEFDS_1264 biopolymer transport protein, ExbD/TolR family; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein, ExbD/TolR family YP_004603716.1 PFAM: Biopolymer transport protein ExbD/TolR; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: ddf:DEFDS_1265 biopolymer transport protein, ExbB/TolQ family; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Biopolymer transport protein, ExbB/TolQ family YP_004603717.1 PFAM: MotA/TolQ/ExbB proton channel family; KEGG: cni:Calni_0635 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603718.1 COGs: COG0496 acid phosphatase; HAMAP: Multifunctional protein surE; InterPro IPR002828; KEGG: ddf:DEFDS_1267 stationary-phase survival protein; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: 5'-nucleotidase surE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase YP_004603719.1 PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099; KEGG: ddf:DEFDS_0705 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_004603720.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; COGs: COG1342 DNA-binding protein; HAMAP: UPF0251 protein; InterPro IPR002852; KEGG: ddf:DEFDS_1700 hypothetical protein; PFAM: Uncharacterised protein family UPF0251; SPTR: UPF0251 protein DEFDS_1700 YP_004603721.1 PFAM: Protein of unknown function DUF134; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006311:IPR006963:IPR006656:IPR006657; KEGG: ddf:DEFDS_1699 molybdopterin oxidoreductase molybdopterin-binding subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; PRIAM: Trimethylamine-N-oxide reductase (cytochrome c); SPTR: Molybdopterin oxidoreductase, molybdopterin-binding subunit YP_004603722.1 PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450; KEGG: ddf:DEFDS_1698 molybdopterin oxidoreductase 4Fe-4S ferredoxin, iron-sulfur binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Molybdopterin oxidoreductase, 4Fe-4S ferredoxin, iron-sulfur binding protein YP_004603723.1 PFAM: 4Fe-4S binding domain; COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: ddf:DEFDS_1697 molybdopterin oxidoreductase membrane subunit; PFAM: Polysulphide reductase, NrfD; SPTR: Molybdopterin oxidoreductase, membrane subunit YP_004603724.1 PFAM: Polysulphide reductase, NrfD; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: ddf:DEFDS_1685 iron-molybdenum cofactor-binding protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Iron-molybdenum cofactor-binding protein YP_004603725.1 PFAM: Dinitrogenase iron-molybdenum cofactor YP_004603726.1 COGs: COG1342 DNA-binding protein; HAMAP: UPF0251 protein; InterPro IPR002852; KEGG: ddf:DEFDS_1690 hypothetical protein; PFAM: Uncharacterised protein family UPF0251; SPTR: UPF0251 protein DEFDS_1690 YP_004603727.1 PFAM: Protein of unknown function DUF134; COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: ddf:DEFDS_1691 molybdopterin oxidoreductase membrane subunit; PFAM: Polysulphide reductase, NrfD; SPTR: Molybdopterin oxidoreductase, membrane subunit YP_004603728.1 PFAM: Polysulphide reductase, NrfD; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450; KEGG: ddf:DEFDS_1692 molybdopterin oxidoreductase 4Fe-4S ferredoxin; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Molybdopterin oxidoreductase, 4Fe-4S ferredoxin YP_004603729.1 PFAM: 4Fe-4S binding domain; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006311:IPR006963:IPR006656:IPR006657; KEGG: ddf:DEFDS_1693 molybdopterin oxidoreductase molybdopterin-binding subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Molybdopterin oxidoreductase, molybdopterin-binding subunit YP_004603730.1 PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603731.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG1533 DNA repair photolyase; KEGG: ddf:DEFDS_1338 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603732.1 KEGG: dap:Dacet_2224 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603733.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR004390:IPR013822:IPR000897:IPR003593; KEGG: ddf:DEFDS_1340 signal recognition particle receptor FtsY; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; SMART: ATPase, AAA+ type, core; SPTR: Signal recognition particle receptor FtsY; TIGRFAM: Cell division transporter substrate-binding protein FtsY YP_004603734.1 PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY; COGs: COG1196 Chromosome segregation ATPase; InterPro IPR011890:IPR003395; KEGG: ddf:DEFDS_1341 chromosome segregation protein SMC; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: Chromosome segregation protein SMC; TIGRFAM: Chromosome segregation protein SMC YP_004603735.1 PFAM: RecF/RecN/SMC N terminal domain; COGs: COG1048 Aconitase A; InterPro IPR006249:IPR001030:IPR000573; KEGG: cni:Calni_1064 aconitase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; PRIAM: Aconitate hydratase; SPTR: Aconitate hydratase; TIGRFAM: Aconitase/iron regulatory protein 2 YP_004603736.1 PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1; InterPro IPR001623; KEGG: cni:Calni_1269 heat shock protein DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein YP_004603737.1 PFAM: DnaJ domain; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: ddf:DEFDS_1499 inositol-phosphate phosphatase; PFAM: Inositol monophosphatase; PRIAM: Inositol-phosphate phosphatase; SPTR: Inositol-phosphate phosphatase YP_004603738.1 PFAM: Inositol monophosphatase family; COGs: COG1485 ATPase; InterPro IPR005654; KEGG: cni:Calni_1271 afg1-family atpase; PFAM: ATPase, AFG1-like; SPTR: AFG1-family ATPase YP_004603739.1 PFAM: AFG1-like ATPase; COGs: COG4866 conserved hypothetical protein; InterPro IPR016732; KEGG: ddf:DEFDS_0806 hypothetical protein; PFAM: Uncharacterised conserved protein UCP018688; SPTR: Putative uncharacterized protein YP_004603740.1 PFAM: Uncharacterized conserved protein (DUF2156); COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: ddf:DEFDS_0807 multidrug resistance protein, MATE family; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: Multidrug resistance protein, MATE family; TIGRFAM: Multi antimicrobial extrusion protein MatE; manually curated YP_004603741.1 PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; InterPro IPR002541; KEGG: dap:Dacet_2906 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein YP_004603742.1 PFAM: Cytochrome C assembly protein; COGs: COG0373 Glutamyl-tRNA reductase; HAMAP: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase; InterPro IPR000343:IPR015895:IPR006151:IPR015896; KEGG: cni:Calni_1982 glutamyl-tRNA reductase; PFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, C-terminal; SPTR: Glutamyl-tRNA reductase; TIGRFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase YP_004603743.1 PFAM: Glutamyl-tRNAGlu reductase, N-terminal domain; Shikimate / quinate 5-dehydrogenase; Glutamyl-tRNAGlu reductase, dimerisation domain; TIGRFAM: glutamyl-tRNA reductase; COGs: COG0181 Porphobilinogen deaminase; HAMAP: Porphobilinogen deaminase; InterPro IPR000860; KEGG: ddf:DEFDS_0810 porphobilinogen deaminase; PFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; SPTR: Porphobilinogen deaminase; TIGRFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase YP_004603744.1 PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase; COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: ddf:DEFDS_0811 uroporphyrinogen-III synthase; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III synthase; SPTR: Uroporphyrinogen-III synthase YP_004603745.1 PFAM: Uroporphyrinogen-III synthase HemD; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: ddf:DEFDS_0812 porphobilinogen synthase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase YP_004603746.1 PFAM: Delta-aminolevulinic acid dehydratase; COGs: COG2607 ATPase (AAA+ superfamily); InterPro IPR008533:IPR003593; KEGG: ddf:DEFDS_0813 hypothetical protein; PFAM: Protein of unknown function DUF815; SMART: ATPase, AAA+ type, core; SPTR: Putative uncharacterized protein YP_004603747.1 PFAM: Protein of unknown function (DUF815); COGs: COG0517 FOG: CBS domain; InterPro IPR000644:IPR002912; KEGG: dvm:DvMF_1585 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; Amino acid-binding ACT; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing protein YP_004603748.1 PFAM: CBS domain; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: afw:Anae109_1451 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related YP_004603749.1 PFAM: ABC transporter; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: axy:AXYL_03133 ABC transporter family protein 47; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter family protein 47 YP_004603750.1 PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: nha:Nham_3647 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator YP_004603751.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: tye:THEYE_A0767 branched-chain amino acid ABC transporter, permease protein; PFAM: Bacterial inner-membrane translocator; SPTR: Branched-chain amino acid ABC transporter, permease protein YP_004603752.1 PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: bmr:BMI_II1199 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative; PFAM: Extracellular ligand-binding receptor; SPTR: Putative uncharacterized protein YP_004603753.1 PFAM: Receptor family ligand binding region; COGs: COG0628 permease; InterPro IPR002549; KEGG: dol:Dole_2006 hypothetical protein; PFAM: Uncharacterised protein family UPF0118; SPTR: Putative uncharacterized protein YP_004603754.1 PFAM: Domain of unknown function DUF20; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR014189:IPR013154:IPR013149; KEGG: gur:Gura_0180 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Alcohol dehydrogenase, zinc-binding domain protein; TIGRFAM: Quinone oxidoreductase putative, PIG3 YP_004603755.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative NAD(P)H quinone oxidoreductase, PIG3 family; COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: ddf:DEFDS_1125 hypothetical protein; PFAM: Diacylglycerol kinase, catalytic region; SMART: Diacylglycerol kinase, catalytic region; SPTR: Putative uncharacterized protein YP_004603756.1 PFAM: Diacylglycerol kinase catalytic domain; KEGG: ddf:DEFDS_1124 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603757.1 COGs: COG2107 periplasmic solute-binding protein; InterPro IPR003794; KEGG: ddf:DEFDS_1123 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603758.1 PFAM: Putative periplasminc binding protein (DUF178); COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: ddf:DEFDS_1121 ABC transporter substrate-binding protein; PFAM: Mammalian cell entry related; SPTR: ABC transporter, substrate-binding protein YP_004603759.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein; COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003439:IPR003593; KEGG: cni:Calni_0909 abc transporter related protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004603760.1 PFAM: ABC transporter; COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: ddf:DEFDS_1119 ABC transporter permease; PFAM: Protein of unknown function DUF140; SPTR: ABC transporter, permease; TIGRFAM: Protein of unknown function DUF140 YP_004603761.1 PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein; COGs: COG0787 Alanine racemase; HAMAP: Alanine racemase; InterPro IPR000821:IPR001608:IPR011079; KEGG: ddf:DEFDS_1118 alanine racemase; PFAM: Alanine racemase, C-terminal; Alanine racemase, N-terminal; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: Alanine racemase YP_004603762.1 PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase; COGs: COG1186 Protein chain release factor B; HAMAP: Peptide chain release factor 2, bacterial; InterPro IPR004374:IPR005139:IPR000352:IPR020853; KEGG: ddf:DEFDS_1117 peptide chain release factor RF-2; PFAM: Class I peptide chain release factor; Peptide chain release factor; SPTR: Peptide chain release factor 2; TIGRFAM: Peptide chain release factor 2 YP_004603763.1 PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: dap:Dacet_1409 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004603764.1 PFAM: Acetyltransferase (GNAT) family; KEGG: ddf:DEFDS_1114 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603765.1 InterPro IPR000620; KEGG: cni:Calni_1273 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein YP_004603766.1 PFAM: EamA-like transporter family; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: ddf:DEFDS_0814 citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase YP_004603767.1 PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; KEGG: ddf:DEFDS_0696 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603768.1 COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846:IPR005843; KEGG: ddf:DEFDS_0735 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; SPTR: Phosphomannomutase YP_004603769.1 PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1866 Phosphoenolpyruvate carboxykinase (ATP); HAMAP: Phosphoenolpyruvate carboxykinase [ATP]; InterPro IPR001272; KEGG: ddf:DEFDS_1461 phosphoenolpyruvate carboxykinase (ATP); PFAM: Phosphoenolpyruvate carboxykinase, ATP-utilising; PRIAM: Phosphoenolpyruvate carboxykinase (ATP); SPTR: Phosphoenolpyruvate carboxykinase [ATP]; TIGRFAM: Phosphoenolpyruvate carboxykinase, ATP-utilising YP_004603770.1 PFAM: Phosphoenolpyruvate carboxykinase; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP); InterPro IPR003615:IPR002711; KEGG: cni:Calni_0828 hnh endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease YP_004603771.1 PFAM: HNH endonuclease; COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR018164:IPR012947:IPR003156:IPR002318; KEGG: ddf:DEFDS_1463 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; Phosphoesterase, DHHA1; SPTR: Alanyl-tRNA synthetase; TIGRFAM: Alanyl-tRNA synthetase, class IIc YP_004603772.1 PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase; KEGG: ddf:DEFDS_1923 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603773.1 PFAM: Poly(hydroxyalcanoate) granule associated protein (phasin); TIGRFAM: poly(hydroxyalkanoate) granule-associated protein; InterPro IPR000086; KEGG: ddf:DEFDS_1922 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase YP_004603774.1 PFAM: NUDIX domain; COGs: COG2902 NAD-specific glutamate dehydrogenase; InterPro IPR007780; KEGG: ddf:DEFDS_1921 NAD-glutamate dehydrogenase; PFAM: Bacterial NAD-glutamate dehydrogenase; SPTR: NAD-glutamate dehydrogenase YP_004603775.1 PFAM: Bacterial NAD-glutamate dehydrogenase; COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: ddf:DEFDS_0496 peptidase M16 family; PFAM: Peptidase M16, N-terminal; Peptidase M16, C-terminal; PRIAM: processing peptidase; SPTR: Peptidase, M16 family YP_004603776.1 PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); COGs: COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; InterPro IPR002818; KEGG: ddf:DEFDS_1436 sigma cross-reacting protein 27A; PFAM: ThiJ/PfpI; SPTR: Sigma cross-reacting protein 27A YP_004603777.1 PFAM: DJ-1/PfpI family; KEGG: cni:Calni_1011 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603778.1 PFAM: Protein of unknown function, DUF400; KEGG: cni:Calni_1012 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603779.1 PFAM: Curli production assembly/transport component CsgG; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273; KEGG: dap:Dacet_1557 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Phage SPO1 DNA polymerase-related protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein YP_004603780.1 PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4; COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382:IPR007085:IPR005252; KEGG: cni:Calni_1014 phosphopantothenoylcysteine decarboxylase; phosphopantothenate-cysteine ligase; PFAM: Flavoprotein; DNA/pantothenate metabolism flavoprotein, C-terminal; PRIAM: Phosphopantothenate--cysteine ligase; SPTR: Phosphopantothenoylcysteine decarboxylase; Phosphopantothenate-cysteine ligase; TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase YP_004603781.1 PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic; InterPro IPR006110:IPR003716; KEGG: dap:Dacet_1559 DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; SPTR: DNA-directed RNA polymerase, omega subunit; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004603782.1 PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit; COGs: COG0194 Guanylate kinase; HAMAP: Guanylate kinase, sub-group; InterPro IPR008145:IPR008144:IPR017665; KEGG: cni:Calni_1016 guanylate kinase; PFAM: Guanylate kinase; PRIAM: Guanylate kinase; SMART: Guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: Guanylate kinase, sub-group YP_004603783.1 PFAM: Guanylate kinase; TIGRFAM: guanylate kinase; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: dap:Dacet_1561 hypothetical protein; PFAM: Domain of unknown function DUF1732; YicC-like, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00255 YP_004603784.1 PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: ddf:DEFDS_1430 hypothetical protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Putative uncharacterized protein YP_004603785.1 PFAM: SPFH domain / Band 7 family YP_004603786.1 PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; COGs: COG1380 Putative effector of murein hydrolase LrgA; InterPro IPR005538; KEGG: ddf:DEFDS_0562 LrgA family protein; PFAM: LrgA; SPTR: LrgA family protein YP_004603787.1 PFAM: LrgA family; COGs: COG1346 Putative effector of murein hydrolase; InterPro IPR007300:IPR005261; KEGG: ddf:DEFDS_0561 LrgB family protein; PFAM: LrgB-like protein; SPTR: LrgB family protein; TIGRFAM: Conserved hypothetical protein CHP00659 YP_004603788.1 PFAM: LrgB-like family; TIGRFAM: TIGR00659 family protein; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: cni:Calni_0640 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase YP_004603789.1 PFAM: RNA pseudouridylate synthase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099; KEGG: gem:GM21_2049 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_004603790.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: cni:Calni_0845 UspA domain-containing protein; PFAM: UspA; SPTR: UspA domain-containing protein YP_004603791.1 PFAM: Universal stress protein family; COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183; KEGG: cni:Calni_0514 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase YP_004603792.1 PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: cni:Calni_1071 histone family protein DNA-binding protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein YP_004603793.1 PFAM: Bacterial DNA-binding protein; COGs: COG0554 Glycerol kinase; HAMAP: Glycerol kinase; InterPro IPR018484:IPR018485:IPR005999; KEGG: dsa:Desal_3151 glycerol kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: Glycerol kinase; SPTR: Glycerol kinase; TIGRFAM: Glycerol kinase YP_004603794.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase; KEGG: hel:HELO_1656 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603795.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156:IPR004610; KEGG: cni:Calni_0058 single-stranded-DNA-specific exonuclease RecJ; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; manually curated YP_004603796.1 PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004603798.1 COGs: COG2378 transcriptional regulator protein; KEGG: ddf:DEFDS_0885 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603800.1 KEGG: tai:Taci_1486 protein of unknown function DUF262; SPTR: Putative uncharacterized protein YP_004603801.1 KEGG: ddf:DEFDS_0890 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603802.1 KEGG: pin:Ping_2476 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603803.1 SPTR: Putative uncharacterized protein YP_004603804.1 COGs: COG1672 ATPase (AAA+ superfamily); InterPro IPR011579:IPR004256; KEGG: saf:SULAZ_0007 ATPase; SPTR: ATPase YP_004603805.1 PFAM: Archaeal ATPase; Archaea bacterial proteins of unknown function; COGs: COG3857 ATP-dependent nuclease subunit B; KEGG: nth:Nther_0840 ATP-dependent nuclease subunit B-like protein; SPTR: ATP-dependent nuclease subunit B-like protein YP_004603806.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212; KEGG: nth:Nther_0841 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase YP_004603807.1 PFAM: UvrD/REP helicase; InterPro IPR007159; KEGG: aac:Aaci_0601 SpoVT/AbrB domain protein; PFAM: Transcription regulator AbrB/SpoV, predicted; SPTR: Virulence associated protein B YP_004603808.1 PFAM: SpoVT / AbrB like domain; COGs: COG1487 nucleic acid-binding protein contains PIN domain; InterPro IPR002716; KEGG: dap:Dacet_0540 PilT protein domain protein; PFAM: PilT protein, N-terminal; SPTR: Virulence associated protein C YP_004603809.1 PFAM: PIN domain YP_004603810.1 InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603811.1 PFAM: Transposase domain (DUF772) YP_004603812.1 KEGG: cni:Calni_1608 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603813.1 COGs: COG1604 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR010172; KEGG: sat:SYN_02247 putative cytoplasmic protein; PFAM: Protein of unknown function DUF324; SPTR: Hypothetical cytosolic protein; TIGRFAM: CRISPR-associated protein, TM1791 YP_004603814.1 PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-B/RAMP module RAMP protein Cmr6; InterPro IPR010160; KEGG: sat:SYN_02248 putative cytoplasmic protein; PFAM: CRISPR-associated protein, TM1791.1; SPTR: Hypothetical cytosolic protein; TIGRFAM: CRISPR-associated protein, TM1791.1 YP_004603815.1 PFAM: CRISPR-associated protein (Cas_Cmr5); TIGRFAM: CRISPR type III-B/RAMP module-associated protein Cmr5; COGs: COG1336 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR013410; KEGG: sat:SYN_02249 hypothetical protein; PFAM: Protein of unknown function DUF324; SPTR: Hypothetical exported protein; TIGRFAM: CRISPR-associated RAMP Cmr4 YP_004603816.1 PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-B/RAMP module RAMP protein Cmr4; COGs: COG1769 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR019117; KEGG: sat:SYN_02250 putative cytoplasmic protein; PFAM: CRISPR-associated protein, Cmr3; SPTR: Hypothetical cytosolic protein YP_004603817.1 PFAM: CRISPR-associated protein (Cas_Cmr3); TIGRFAM: CRISPR type III-B/RAMP module-associated protein Cmr3; COGs: COG1353 hydrolase of the HD superfamily (permuted catalytic motifs); InterPro IPR013407; KEGG: sat:SYN_02251 HD superfamily hydrolase; SPTR: Hydrolase of the HD superfamily; TIGRFAM: CRISPR-associated protein Crm2 YP_004603818.1 PFAM: CRISPR-associated protein; TIGRFAM: CRISPR-associated protein Cas10/Cmr2, subtype III-B; COGs: COG1367 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR007522; KEGG: sat:SYN_02252 putative cytoplasmic protein; PFAM: Protein of unknown function DUF324; SPTR: Hypothetical cytosolic protein; TIGRFAM: CRISPR-associated protein TM1795 family, N-terminal YP_004603819.1 PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-B/RAMP module RAMP protein Cmr1; InterPro IPR011742:IPR013383; KEGG: ttm:Tthe_2633 CRISPR-associated protein, TM1812 family; PFAM: CRISPR-associated protein, TM1812; SPTR: CRISPR-associated protein, TM1812 family; TIGRFAM: CRISPR-associated protein, TM1812; CRISPR-associated protein DxTHG, conserved site YP_004603820.1 PFAM: CRISPR-associated protein (cas_TM1812); TIGRFAM: CRISPR-associated protein, TM1812 family; CRISPR-associated DxTHG motif protein; KEGG: cni:Calni_1615 crispr-associated protein cas6; SPTR: CRISPR-associated protein Cas6 YP_004603821.1 PFAM: Uncharacterized conserved protein (DUF2276); InterPro IPR002059; KEGG: cni:Calni_1600 hypothetical protein; PFAM: Cold-shock protein, DNA-binding; SPTR: Putative uncharacterized protein YP_004603822.1 PFAM: 'Cold-shock' DNA-binding domain; COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR003799; KEGG: cni:Calni_1597 crispr-associated protein cas2; SPTR: CRISPR-associated protein Cas2; TIGRFAM: Protein of unknown function DUF196 YP_004603823.1 PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2; COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729; KEGG: cni:Calni_1599 crispr-associated protein cas1; PFAM: CRISPR-associated protein Cas1; SPTR: CRISPR-associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1 YP_004603824.1 PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1; COGs: COG4951 conserved hypothetical protein; KEGG: cni:Calni_1598 DNA primase small subunit; SPTR: DNA primase small subunit YP_004603825.1 KEGG: cni:Calni_1607 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603826.1 InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603827.1 PFAM: Transposase DDE domain; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603828.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); KEGG: cni:Calni_1606 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603829.1 KEGG: cni:Calni_1605 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603830.1 KEGG: cni:Calni_1604 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603831.1 InterPro IPR018973; KEGG: dat:HRM2_14650 Dbp; PFAM: Protein of unknown function DUF1998; SPTR: Dbp YP_004603832.1 PFAM: Domain of unknown function (DUF1998); manually curated YP_004603833.1 InterPro IPR002104; KEGG: dap:Dacet_1090 integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Integrase family protein YP_004603834.1 PFAM: Domain of unknown function (DUF3596); Phage integrase family YP_004603835.1 PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme YP_004603836.1 COGs: COG5421 Transposase; InterPro IPR002559; KEGG: dal:Dalk_4290 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Putative uncharacterized protein YP_004603837.1 PFAM: Transposase DDE domain; KEGG: dal:Dalk_2552 transposase IS4 family protein; SPTR: Transposase IS4 family protein YP_004603838.1 InterPro IPR007712:IPR012753; KEGG: ana:asl4561 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: Putative uncharacterized protein; TIGRFAM: Addiction module toxin, RelE/StbE YP_004603839.1 PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family YP_004603840.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: ppd:Ppro_1126 phage integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Phage integrase family protein YP_004603841.1 PFAM: Phage integrase family; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: cni:Calni_0772 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA YP_004603842.1 PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); HAMAP: Ribosomal RNA adenine dimethylase; InterPro IPR020598:IPR001737:IPR011530; KEGG: cni:Calni_0771 dimethyladenosine transferase; PFAM: Ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase, N-terminal; SPTR: Ribosomal RNA small subunit methyltransferase A; TIGRFAM: Ribosomal RNA adenine dimethylase YP_004603843.1 PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase; COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR006055:IPR013520:IPR006054; KEGG: ddf:DEFDS_1873 hypothetical protein; PFAM: Exonuclease, RNase T/DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit YP_004603844.1 PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; COGs: COG4147 symporter; InterPro IPR001734:IPR019900; KEGG: afw:Anae109_3836 SSS family solute/sodium (Na+) symporter; PFAM: Sodium/solute symporter; SPTR: SSS sodium solute transporter superfamily; TIGRFAM: Sodium/solute symporter, subgroup YP_004603845.1 PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; COGs: COG3162 membrane protein; InterPro IPR007436; KEGG: dap:Dacet_1118 hypothetical protein; PFAM: Protein of unknown function DUF485; SPTR: Putative uncharacterized protein YP_004603846.1 PFAM: Protein of unknown function, DUF485; COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000595:IPR000644:IPR005105:IPR018821; KEGG: cni:Calni_0767 cbs domain and cyclic nucleotide-regulated nucleotidyltransferase; PFAM: Protein of unknown function DUF294, nucleotidyltransferase putative; Cystathionine beta-synthase, core; Cyclic nucleotide-binding; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: Cyclic nucleotide-binding; Cystathionine beta-synthase, core; SPTR: Putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase YP_004603847.1 PFAM: Putative nucleotidyltransferase substrate binding domain; CBS domain; Cyclic nucleotide-binding domain; Putative nucleotidyltransferase DUF294; KEGG: dap:Dacet_0906 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603848.1 KEGG: ddf:DEFDS_2030 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603849.1 COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: cni:Calni_1857 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00730 YP_004603850.1 PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003661:IPR003594:IPR003660:IPR 013767:IPR013656; KEGG: gur:Gura_2743 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold-4; HAMP linker domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS YP_004603851.1 PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: cni:Calni_0192 hypothetical protein; PFAM: ABC transporter substrate binding protein; SPTR: Putative uncharacterized protein YP_004603852.1 PFAM: ABC transporter substrate binding protein; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: dde:Dde_3036 hypothetical protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SPTR: CBS protein YP_004603853.1 PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: gbm:Gbem_0270 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted YP_004603854.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3152 membrane protein; InterPro IPR008523; KEGG: cpb:Cphamn1_0612 protein of unknown function DUF805; PFAM: Protein of unknown function DUF805; SPTR: Putative uncharacterized protein YP_004603855.1 PFAM: Protein of unknown function (DUF805); COGs: COG0412 Dienelactone hydrolase; InterPro IPR002925; KEGG: dap:Dacet_0983 dienelactone hydrolase; PFAM: Dienelactone hydrolase; SPTR: Dienelactone hydrolase YP_004603856.1 PFAM: Dienelactone hydrolase family YP_004603857.1 PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004603858.1 PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; COGs: COG0264 Translation elongation factor Ts; HAMAP: Elongation factor Ts; InterPro IPR000449:IPR014039:IPR001816; KEGG: ddf:DEFDS_0050 translation elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B, dimerisation; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; SPTR: Elongation factor Ts; TIGRFAM: Translation elongation factor EFTs/EF1B YP_004603859.1 PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047; KEGG: ddf:DEFDS_0078 sucrose phosphorylase; PFAM: Glycosyl hydrolase, family 13, catalytic region; PRIAM: Sucrose phosphorylase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Sucrose phosphorylase YP_004603860.1 PFAM: Alpha amylase, catalytic domain; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: cni:Calni_0188 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist YP_004603861.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_004603862.1 PFAM: 2-nitropropane dioxygenase; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254:IPR011782; KEGG: ddf:DEFDS_1060 peptidase S1C, Do; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF; SPTR: Peptidase S1C, Do; TIGRFAM: Peptidase S1C, Do YP_004603863.1 PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; KEGG: cni:Calni_0954 sigma e regulatory protein, MucB/rseb; SPTR: Putative sigma E regulatory protein, MucB/RseB YP_004603864.1 KEGG: dap:Dacet_1972 putative transmembrane anti-sigma factor; SPTR: Putative transmembrane anti-sigma factor YP_004603865.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: ddf:DEFDS_1057 DNA-directed RNA polymerase sigma 70 factor; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70 YP_004603866.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603867.1 PFAM: Transposase DDE domain; InterPro IPR003251; KEGG: ddf:DEFDS_0850 hypothetical protein; PFAM: Rubrerythrin; SPTR: Putative uncharacterized protein YP_004603868.1 PFAM: Rubrerythrin; manually curated YP_004603869.1 PFAM: Cupin domain; Helix-turn-helix; COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: sta:STHERM_c04700 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin YP_004603870.1 PFAM: Rubredoxin; COGs: COG0426 flavoprotein; InterPro IPR008254; KEGG: ddf:DEFDS_0572 rubredoxin-oxygen oxidoreductase; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Rubredoxin-oxygen oxidoreductase YP_004603871.1 PFAM: Flavodoxin; Metallo-beta-lactamase superfamily; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: ddf:DEFDS_0571 K+ transport (Trk) system NAD-binding component; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: K+ transport (Trk) system, NAD-binding component YP_004603872.1 PFAM: TrkA-N domain; TrkA-C domain; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: ddf:DEFDS_0570 K+ transport (Trk) system membrane component; PFAM: Cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: K+ transport (Trk) system, membrane component YP_004603873.1 PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family; InterPro IPR004039; KEGG: dal:Dalk_5026 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Putative uncharacterized protein YP_004603874.1 PFAM: Rubredoxin; COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: ddf:DEFDS_1556 nitrogen-fixing NifU domain protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; SPTR: Nitrogen-fixing NifU domain protein YP_004603875.1 PFAM: NifU-like domain; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871:IPR017787; KEGG: cni:Calni_1679 fes cluster assembly scaffold protein NifU; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: FeS cluster assembly scaffold protein NifU; TIGRFAM: NIF system FeS cluster assembly, NifU-like YP_004603876.1 PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold IscU; FeS cluster assembly scaffold protein NifU, Clostridium type; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: ddf:DEFDS_1558 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase YP_004603877.1 PFAM: Aminotransferase class-V; KEGG: dap:Dacet_1242 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603878.1 COGs: COG1426 conserved hypothetical protein; InterPro IPR001387; KEGG: ddf:DEFDS_1560 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Putative uncharacterized protein YP_004603879.1 PFAM: Helix-turn-helix; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR013105:IPR001440; KEGG: ddf:DEFDS_1561 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein YP_004603880.1 PFAM: Tetratricopeptide repeat; COGs: COG1521 Putative transcriptional regulator protein; HAMAP: Type III pantothenate kinase; InterPro IPR004619; KEGG: cni:Calni_1675 pantothenate kinase; PFAM: Bordetella pertussis Bvg accessory factor; PRIAM: Pantothenate kinase; SPTR: Type III pantothenate kinase; TIGRFAM: Bordetella pertussis Bvg accessory factor YP_004603881.1 PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III; COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143:IPR003142:IPR004408; KEGG: dap:Dacet_1239 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase YP_004603882.1 PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cni:Calni_1673 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein YP_004603883.1 PFAM: Response regulator receiver domain; manually curated YP_004603884.1 PFAM: Desulfoferrodoxin, N-terminal domain; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; COGs: COG0217 conserved hypothetical protein; HAMAP: Protein of unknown function DUF28; InterPro IPR002876; KEGG: ddf:DEFDS_1661 hypothetical protein; PFAM: Protein of unknown function DUF28; SPTR: UPF0082 protein DEFDS_1661; TIGRFAM: Protein of unknown function DUF28 YP_004603885.1 PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family; COGs: COG0817 Holliday junction resolvasome endonuclease subunit; HAMAP: Crossover junction endodeoxyribonuclease RuvC; InterPro IPR002176; KEGG: dap:Dacet_0474 crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: Crossover junction endodeoxyribonuclease RuvC YP_004603886.1 PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; HAMAP: Holliday junction ATP-dependent DNA helicase ruvA; InterPro IPR013849:IPR000445:IPR011114:IPR000085; KEGG: dap:Dacet_0475 Holliday junction DNA helicase RuvA; PFAM: DNA helicase, Holliday junction RuvA type, domain I, bacterial; Helix-hairpin-helix motif; DNA helicase, Holliday junction RuvA type, domain III, C-terminal; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Bacterial DNA recombination protein RuvA YP_004603887.1 PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ddf:DEFDS_0602 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase YP_004603888.1 PFAM: Glycosyl transferases group 1; COGs: COG0206 Cell division GTPase; InterPro IPR003008:IPR018316:IPR000158; KEGG: ddf:DEFDS_0601 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: Cell division protein FtsZ, N-terminal YP_004603889.1 PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ; COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494:IPR020823; KEGG: ddf:DEFDS_0600 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA YP_004603890.1 PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA; InterPro IPR013685; KEGG: dap:Dacet_2198 hypothetical protein; PFAM: Polypeptide-transport-associated, FtsQ-type; SPTR: Putative uncharacterized protein YP_004603891.1 PFAM: POTRA domain, FtsQ-type; COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; HAMAP: D-alanine--D-alanine ligase; InterPro IPR011127:IPR011095:IPR005905; KEGG: cni:Calni_1723 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase, C-terminal; D-alanine--D-alanine ligase, N-terminal; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase YP_004603892.1 PFAM: D-ala D-ala ligase N-terminus; D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; HAMAP: UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221:IPR004101:IPR005758; KEGG: cni:Calni_1724 UDP-N-acetylmuramate--L-alanine ligase; PFAM: Mur ligase, N-terminal; Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramate--L-alanine ligase; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate-alanine ligase YP_004603893.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase; COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; HAMAP:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; InterPro IPR004276:IPR007235; KEGG: ddf:DEFDS_0596 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: Glycosyl transferase, family 28, C-terminal; Glycosyl transferase, family 28; PRIAM: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase YP_004603894.1 PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: cni:Calni_1726 cell division protein FtsW; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW YP_004603895.1 PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; HAMAP: UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR013221:IPR004101:IPR005762; KEGG: cni:Calni_1727 UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase YP_004603896.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; HAMAP: Phospho-N-acetylmuramoyl-pentapeptide transferase; InterPro IPR018480:IPR018481:IPR003524; KEGG: ddf:DEFDS_0593 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4, conserved region; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:Phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM: Phospho-N-acetylmuramoyl-pentapeptide transferase YP_004603897.1 PFAM: Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; Glycosyl transferase family 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR000713:IPR013221:IPR005863; KEGG: cni:Calni_1729 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; PRIAM:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-a lanineligase; SPTR:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diam inopimelate/D-alanyl-D-alanylligase; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase YP_004603898.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; HAMAP:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di aminopimelateligase; InterPro IPR000713:IPR013221:IPR004101:IPR005761; KEGG: cni:Calni_1730 UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelateligase; SPTR: UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelateligase YP_004603899.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: cni:Calni_1731 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase YP_004603900.1 PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; KEGG: ddf:DEFDS_0589 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603901.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; HAMAP: S-adenosyl-L-methionine-dependent methyltransferase, MraW; InterPro IPR002903; KEGG: ddf:DEFDS_0588 S-adenosyl-methyltransferase; PFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW YP_004603902.1 PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW; COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR020603:IPR003444; KEGG: cni:Calni_1734 mraz protein; PFAM: MraZ domain; SPTR: Protein MraZ; TIGRFAM: MraZ YP_004603903.1 PFAM: MraZ protein; TIGRFAM: mraZ protein; COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); HAMAP: ATPase, F1 complex, delta/epsilon subunit; InterPro IPR020546:IPR020547:IPR001469; KEGG: ddf:DEFDS_1885 F0F1-type ATP synthase subunit epsilon; PFAM: ATPase, F1 complex, delta/epsilon subunit, N-terminal; ATPase, F1 complex, delta/epsilon subunit, C-terminal; SPTR: ATP synthase epsilon chain; TIGRFAM: ATPase, F1 complex, delta/epsilon subunit YP_004603904.1 PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain; ATP synthase, Delta/Epsilon chain, long alpha-helix domain; TIGRFAM: ATP synthase, F1 epsilon subunit (delta in mitochondria); COGs: COG0055 F0F1-type ATP synthase beta subunit; HAMAP: ATPase, F1 complex, beta subunit; InterProIPR003593:IPR004100:IPR000194:IPR000793:IPR 005722; KEGG: ddf:DEFDS_1886 F0F1-type ATP synthase subunit beta; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP synthase subunit beta; TIGRFAM: ATPase, F1 complex, beta subunit YP_004603905.1 PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; TIGRFAM: ATP synthase, F1 beta subunit; COGs: COG0224 F0F1-type ATP synthase gamma subunit; HAMAP: ATP synthase gamma chain; InterPro IPR000131; KEGG: ddf:DEFDS_1887 F0F1-type ATP synthase subunit gamma; PFAM: ATPase, F1 complex, gamma subunit; SPTR: ATP synthase gamma chain; TIGRFAM: ATPase, F1 complex, gamma subunit YP_004603906.1 PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit; COGs: COG0056 F0F1-type ATP synthase alpha subunit; HAMAP: ATPase, F1 complex, alpha subunit; InterPro IPR004100:IPR000194:IPR000793:IPR005294; KEGG: cni:Calni_1589 ATP synthase f1 subcomplex alpha subunit; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SPTR: ATP synthase subunit alpha; TIGRFAM: ATPase, F1 complex, alpha subunit YP_004603907.1 PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; TIGRFAM: proton translocating ATP synthase, F1 alpha subunit; COGs: COG0712 F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); HAMAP: ATPase, F1 complex, OSCP/delta subunit; InterPro IPR000711; KEGG: ddf:DEFDS_1889 F0F1-type ATP synthase subunit delta; PFAM: ATPase, F1 complex, OSCP/delta subunit; SPTR: ATP synthase subunit delta; TIGRFAM: ATPase, F1 complex, OSCP/delta subunit YP_004603908.1 PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit; COGs: COG0711 F0F1-type ATP synthase subunit b; HAMAP: ATP synthase subunit b; InterPro IPR002146:IPR005864; KEGG: cni:Calni_1591 h+transporting two-sector atpase B/b' subunit; PFAM: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; SPTR: H+transporting two-sector ATPase B/B' subunit; TIGRFAM: ATPase, F0 complex, subunit B, bacterial YP_004603909.1 PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b; HAMAP: ATP synthase subunit b; InterPro IPR002146; KEGG: ddf:DEFDS_1891 F0F1-type ATP synthase B' subunit; PFAM: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; SPTR: F0F1-type ATP synthase, B' subunit YP_004603910.1 PFAM: ATP synthase B/B' CF(0); COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: gme:Gmet_2645 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family YP_004603911.1 PFAM: YsiA-like protein, C-terminal region; Bacterial regulatory proteins, tetR family; KEGG: gur:Gura_3349 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603912.1 manually curated YP_004603913.1 PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603914.1 InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004603915.1 PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603916.1 PFAM: Transposase domain (DUF772); manually curated YP_004603917.1 PFAM: IstB-like ATP binding protein; COGs: COG4584 Transposase and inactivated derivatives; KEGG: toc:Toce_1959 integrase catalytic region; SPTR: Integrase catalytic region YP_004603918.1 PFAM: Integrase core domain; InterPro IPR004370; KEGG: ddf:DEFDS_1325 4-oxalocrotonate tautomerase; PFAM: 4-oxalocrotonate tautomerase; SPTR: 4-oxalocrotonate tautomerase YP_004603919.1 PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; COGs: COG2951 Membrane-bound lytic murein transglycosylase B; KEGG: ddf:DEFDS_0819 membrane-bound lytic murein transglycosylase B; SPTR: Membrane-bound lytic murein transglycosylase B YP_004603920.1 TIGRFAM: lytic murein transglycosylase B; InterPro IPR004096; KEGG: dat:HRM2_39440 hypothetical protein; PFAM: 4-vinyl reductase, 4VR; SPTR: Putative uncharacterized protein YP_004603921.1 PFAM: V4R domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dds:Ddes_0422 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase YP_004603922.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603923.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); manually curated YP_004603924.1 PFAM: Quinolinate synthetase A protein; TIGRFAM: quinolinate synthetase complex, A subunit; COGs: COG1692 conserved hypothetical protein; InterPro IPR004843; KEGG: ddf:DEFDS_0482 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: Putative uncharacterized protein YP_004603925.1 TIGRFAM: metallophosphoesterase, MG_246/BB_0505 family; COGs: COG1418 HD superfamily hydrolase; HAMAP: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; InterProIPR004087:IPR003607:IPR018111:IPR006674:IPR 017705:IPR006675; KEGG: ddf:DEFDS_0481 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; K Homology, type 1, subgroup; SMART: Metal-dependent phosphohydrolase, HD region; K Homology; SPTR: Putative uncharacterized protein; TIGRFAM: 2,3-cyclic-nucleotide 2-phosphodiesterase; HDIG YP_004603926.1 PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG; COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: ddf:DEFDS_0480 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase YP_004603927.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: cni:Calni_0332 aaa atpase central domain protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase central domain protein YP_004603928.1 PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA); 6S / SsrS RNA as predicted by Rfam (RF00013), score 108.25 YP_004603929.1 PFAM: Cell division protein ZapA; KEGG: dap:Dacet_1925 hypothetical protein YP_004603930.1 PFAM: Protein of unknown function (DUF904); COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR002547:IPR005146:IPR005147:IPR005121:IPR 004532; KEGG: ddf:DEFDS_1621 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding region; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial YP_004603931.1 PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain; InterPro IPR004188:IPR002319:IPR004529; KEGG: ddf:DEFDS_1622 phenylalanyl-tRNA synthetase subunit alpha; PFAM: Phenylalanyl-tRNA synthetase alpha chain; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit YP_004603932.1 PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; COGs: COG0292 Ribosomal protein L20; HAMAP: Ribosomal protein L20; InterPro IPR005813; KEGG: ddf:DEFDS_1501 50S ribosomal protein L20; PFAM: Ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: Ribosomal protein L20 YP_004603933.1 PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20; HAMAP: Ribosomal protein L35; InterPro IPR001706; KEGG: ddf:DEFDS_1502 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: Ribosomal protein L35 YP_004603934.1 PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; COGs: COG0290 Translation initiation factor 3 (IF-3); HAMAP: Translation initiation factor IF-3; InterPro IPR019814:IPR019815:IPR001288; KEGG: cni:Calni_1323 bacterial translation initiation factor 3 (bif-3); PFAM: Translation initiation factor 3, C-terminal; Translation initiation factor 3, N-terminal; SPTR: Translation initiation factor IF-3; TIGRFAM: Translation initiation factor 3; manually curated YP_004603935.1 PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR004095:IPR012947:IPR002314:IPR004154:IPR 002320; KEGG: ddf:DEFDS_1504 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; SPTR: Threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa YP_004603936.1 PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TGS domain; TIGRFAM: threonyl-tRNA synthetase; This gene is disrupted by insertion of repetitive element; manually curated YP_004603937.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603938.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG0566 rRNA methylase; InterPro IPR001537:IPR004441; KEGG: cni:Calni_0015 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3 YP_004603939.1 PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; InterPro IPR011642; KEGG: ddf:DEFDS_2159 hypothetical protein; PFAM: Nucleoside recognition; SPTR: Putative uncharacterized protein YP_004603940.1 PFAM: Nucleoside recognition; KEGG: ddf:DEFDS_2158 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603941.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: ddf:DEFDS_0392 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603942.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: dat:HRM2_48360 TolC; PFAM: Outer membrane efflux protein; SPTR: TolC YP_004603943.1 PFAM: Outer membrane efflux protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: dat:HRM2_48370 NolG; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein YP_004603944.1 PFAM: AcrB/AcrD/AcrF family; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_48380 putative membrane-fusion protein; PFAM: Secretion protein HlyD; SPTR: Putative membrane-fusion protein; TIGRFAM: Secretion protein HlyD YP_004603945.1 PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: ant:Arnit_0841 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family protein YP_004603946.1 PFAM: MarR family; KEGG: ddf:DEFDS_1152 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603947.1 InterPro IPR008815:IPR012902; KEGG: nam:NAMH_1676 S23 ribosomal; PFAM: 23S rRNA-associated protein; Prepilin-type cleavage/methylation, N-terminal; SPTR: S23 ribosomal YP_004603948.1 PFAM: S23 ribosomal protein; InterPro IPR012902; KEGG: cni:Calni_0394 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603949.1 TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; InterPro IPR008815; KEGG: dba:Dbac_2569 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein YP_004603950.1 PFAM: S23 ribosomal protein; InterPro IPR012902; KEGG: cni:Calni_0395 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603951.1 PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; KEGG: cni:Calni_0396 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603952.1 InterPro IPR002559; KEGG: glo:Glov_3666 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004603953.1 PFAM: Transposase domain (DUF772); manually curated YP_004603954.1 PFAM: Transposase domain (DUF772); KEGG: dae:Dtox_1626 transposase IS4 family protein; SPTR: Transposase IS4 family protein YP_004603955.1 manually curated YP_004603956.1 PFAM: Integrase core domain; InterPro IPR002525; KEGG: sul:SYO3AOP1_1339 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS111A/IS1328/IS1533; SPTR: Transposase IS116/IS110/IS902 family protein YP_004603957.1 PFAM: Transposase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mmq:MmarC5_1142 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase YP_004603958.1 PFAM: NADPH-dependent FMN reductase; COGs: COG0815 Apolipoprotein N-acyltransferase; HAMAP: Apolipoprotein N-acyltransferase; InterPro IPR003010:IPR004563; KEGG: ddf:DEFDS_0986 apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase; TIGRFAM: Apolipoprotein N-acyltransferase YP_004603959.1 PFAM: Carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase; HAMAP: Twin-arginine translocation protein TatA/E; InterPro IPR003369:IPR006312; KEGG: ddf:DEFDS_0987 twin-arginine translocation protein, TatA/E family; PFAM: Bacterial sec-independent translocation protein mttA/Hcf106; SPTR: Sec-independent protein translocase protein tatA/E homolog 1; TIGRFAM: Twin-arginine translocation protein TatA/E YP_004603960.1 PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family; COGs: COG4012 conserved hypothetical protein; InterPro IPR014846; KEGG: ddf:DEFDS_0988 hypothetical protein; PFAM: Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme; SPTR: Putative uncharacterized protein YP_004603961.1 PFAM: Putative pyruvate format-lyase activating enzyme (DUF1786); COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: ddf:DEFDS_0989 cobalt/nickel ABC transporter permease; PFAM: Cobalt transport protein; SPTR: Cobalt/nickel ABC transporter, permease YP_004603962.1 PFAM: Cobalt transport protein; COGs: COG0101 Pseudouridylate synthase; HAMAP: Pseudouridine synthase I, TruA; InterPro IPR020097:IPR001406; KEGG: cni:Calni_0390 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: Pseudouridine synthase I, TruA YP_004603963.1 PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I; KEGG: cni:Calni_0034 hypothetical protein YP_004603964.1 KEGG: ddf:DEFDS_1354 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603966.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ilo:IL0120 membrane-associated protein; PFAM: Glycosyl transferase, group 1; SPTR: Membrane-associated protein YP_004603967.1 PFAM: Glycosyl transferases group 1; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603968.1 PFAM: Transposase DDE domain; Transposase domain (DUF772) YP_004603969.1 InterPro IPR005242; KEGG: maq:Maqu_3008 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603970.1 PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein; COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; HAMAP: Thiazole biosynthesis; InterPro IPR008867; KEGG: cni:Calni_0489 thiazole-phosphate synthase; PFAM: Thiazole biosynthesis; SPTR: Thiazole synthase YP_004603971.1 PFAM: Thiazole biosynthesis protein ThiG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR012726; KEGG: cni:Calni_0488 tyrosine lyase thih; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SPTR: Tyrosine lyase ThiH; TIGRFAM: Thiazole biosynthesis ThiH YP_004603972.1 PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR010280; KEGG: ddf:DEFDS_0222 tRNA (uracil-5-)-methyltransferase; PFAM: Deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; SPTR: tRNA (Uracil-5-)-methyltransferase YP_004603973.1 PFAM: tRNA (Uracil-5-)-methyltransferase; TRAM domain YP_004603974.1 InterPro IPR003660:IPR004010; KEGG: dat:HRM2_16030 hypothetical protein; PFAM: HAMP linker domain; Cache; SMART: HAMP linker domain; SPTR: Putative uncharacterized protein YP_004603975.1 PFAM: HAMP domain; Cache domain; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: cni:Calni_1306 chromosome segregation atpase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Chromosome segregation ATPase YP_004603976.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: ddf:DEFDS_0127 chromosome partitioning protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: Chromosome partitioning protein ParB; TIGRFAM: ParB-like partition protein YP_004603977.1 PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: ddf:DEFDS_0128 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: Putative uncharacterized protein YP_004603978.1 PFAM: Protein of unknown function, DUF583; COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652; KEGG: cni:Calni_1303 triosephosphate isomerase; PFAM: Triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: Triosephosphate isomerase YP_004603979.1 PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; COGs: COG1314 Preprotein translocase subunit SecG; InterPro IPR004692; KEGG: cni:Calni_0863 preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: Preprotein translocase SecG subunit YP_004603980.1 PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: ddf:DEFDS_0131 peptide/nickel ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Peptide/nickel ABC transporter, substrate-binding protein YP_004603981.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: ddf:DEFDS_0132 peptide/nickel ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Peptide/nickel ABC transporter, permease YP_004603982.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dap:Dacet_2982 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004603983.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: cni:Calni_0358 nad-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase YP_004603984.1 PFAM: NAD dependent epimerase/dehydratase family; COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: dap:Dacet_2445 DNA repair protein RadC; PFAM: DNA repair, RadC-like; SPTR: DNA repair protein RadC; TIGRFAM: DNA repair, RadC-like; manually curated YP_004603985.1 PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; manually curated YP_004603986.1 KEGG: kol:Kole_0062 DNA methylase N-4/N-6 domain protein; SPTR: Methyltransferase YP_004603987.1 PFAM: Type III restriction/modification enzyme methylation subunit; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004603988.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); manually curated YP_004603989.1 PFAM: Type III restriction enzyme, res subunit; KEGG: bhy:BHWA1_00405 type II restriction-modification enzyme; SPTR: Type II restriction-modification enzyme YP_004603990.1 KEGG: mta:Moth_0637 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603991.1 KEGG: shc:Shell_0165 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603992.1 KEGG: sbm:Shew185_3249 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603993.1 KEGG: gvi:glr4337 hypothetical protein; SPTR: Glr4337 protein YP_004603994.1 PFAM: Protein of unknwon function (DUF2893); COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: ddf:DEFDS_1268 ATP-binding protein, CobQ/CobB/MinD/ParA family; PFAM: ATPase-like, ParA/MinD; SPTR: ATP-binding protein, CobQ/CobB/MinD/ParA family YP_004603995.1 PFAM: ParA/MinD ATPase like; Anion-transporting ATPase; TIGRFAM: YgiT-type zinc finger domain; COGs: COG1038 Pyruvate carboxylase; InterProIPR005481:IPR005479:IPR005482:IPR000891:IPR 003379:IPR000089:IPR005930; KEGG: cni:Calni_0495 pyruvate carboxylase; PFAM: Conserved carboxylase region; Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; Pyruvate carboxyltransferase; Biotin/lipoyl attachment; PRIAM: Pyruvate carboxylase; SPTR: Pyruvate carboxylase; TIGRFAM: Pyruvate carboxylase YP_004603996.1 PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; HMGL-like; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; Conserved carboxylase domain; TIGRFAM: pyruvate carboxylase; COGs: COG0301 Thiamine biosynthesis ATP pyrophosphatase; HAMAP: Thiamine biosynthesis protein; InterPro IPR004114:IPR020536:IPR003720; KEGG: ddf:DEFDS_1945 thiamine biosynthesis protein ThiI; PFAM: Thiamine biosynthesis protein, C-terminal; THUMP; SPTR: Probable tRNA sulfurtransferase; TIGRFAM: Thiamine biosynthesis protein YP_004603997.1 PFAM: Thiamine biosynthesis protein (ThiI); THUMP domain; TIGRFAM: thiazole biosynthesis/tRNA modification protein ThiI; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: ddf:DEFDS_1944 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase, class V YP_004603998.1 PFAM: Aminotransferase class-V; KEGG: dap:Dacet_0519 hypothetical protein; SPTR: Putative uncharacterized protein YP_004603999.1 COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006657; KEGG: ddf:DEFDS_1943 hypothetical protein; PFAM: Molydopterin dinucleotide-binding region; SPTR: Putative uncharacterized protein YP_004604000.1 PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR003593:IPR003439:IPR005670; KEGG: drt:Dret_0469 phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter-like; PRIAM: Phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Phosphate ABC transporter, ATPase subunit; TIGRFAM: Phosphate transport system permease protein 1 YP_004604001.1 PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: drt:Dret_0466 phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: Phosphate transport system permease protein 2 YP_004604002.1 PFAM: Binding-protein-dependent transport system inner membrane component; Domain of unknown function (DUF3333); TIGRFAM: phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR011864; KEGG: cch:Cag_0500 phosphate ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter membrane protein 1, PhoT family; TIGRFAM: Phosphate ABC transporter, permease protein PstC YP_004604003.1 PFAM: Binding-protein-dependent transport system inner membrane component; Phosphate ATP-binding cassette transporter; TIGRFAM: phosphate ABC transporter, permease protein PstC; COGs: COG0226 ABC-type phosphate transport system periplasmic component; KEGG: drt:Dret_0464 periplasmic phosphate binding protein; SPTR: Periplasmic phosphate binding protein YP_004604004.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: ddf:DEFDS_1239 polar amino acid ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid ABC transporter, permease; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_004604005.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638:IPR001320; KEGG: ddf:DEFDS_1238 polar amino acid ABC transporter substrate-binding protein; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; Ionotropic glutamate receptor; SPTR: Polar amino acid ABC transporter, substrate-binding protein YP_004604006.1 PFAM: Bacterial extracellular solute-binding proteins, family 3; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: drt:Dret_0475 polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; manually curated YP_004604007.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; HAMAP: UDP-N-acetylenolpyruvoylglucosamine reductase; InterPro IPR006094:IPR011601:IPR003170; KEGG: cni:Calni_0129 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004604008.1 PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845; KEGG: dap:Dacet_0477 purine or other phosphorylase family 1; PFAM: Nucleoside phosphorylase; PRIAM: S-methyl-5'-thioadenosine phosphorylase; SPTR: Purine or other phosphorylase family 1 YP_004604009.1 PFAM: Phosphorylase superfamily; TIGRFAM: 5'-deoxy-5'-methylthioadenosine phosphorylase; COGs: COG2860 membrane protein; InterPro IPR005115; KEGG: ddf:DEFDS_0473 hypothetical protein; PFAM: Uncharacterised protein family UPF0126; SPTR: Putative uncharacterized protein YP_004604010.1 PFAM: UPF0126 domain; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: dap:Dacet_0476 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004604011.1 PFAM: ABC transporter; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838:IPR011925; KEGG: ddf:DEFDS_0471 lipoprotein-releasing system permease protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Lipoprotein-releasing system permease protein; TIGRFAM: Lipoprotein releasing system, transmembrane protein, LolC/E family YP_004604012.1 PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase [glutamine-hydrolyzing]; InterPro IPR000991:IPR018318:IPR001674:IPR004739; KEGG: cni:Calni_0134 gmp synthase (glutamine-hydrolyzing); PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transferase-like; PRIAM: GMP synthase (glutamine-hydrolyzing); SPTR: GMP synthase [glutamine-hydrolyzing]; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal YP_004604013.1 PFAM: Glutamine amidotransferase class-I; GMP synthase C terminal domain; Asparagine synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR000644:IPR001093:IPR005990; KEGG: ddf:DEFDS_0469 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; PRIAM: IMP dehydrogenase; SMART: Cystathionine beta-synthase, core; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase YP_004604014.1 PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; COGs: COG0171 NAD synthase; HAMAP: NH(3)-dependent NAD(+) synthetase; InterPro IPR003694; KEGG: cni:Calni_0136 nh(3)-dependent nad(+) synthetase; PFAM: NAD+ synthase; SPTR: NH(3)-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthase YP_004604015.1 PFAM: NAD synthase; TIGRFAM: NAD+ synthetase; COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: ddf:DEFDS_0467 hydrolase carbon-nitrogen family; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Hydrolase, carbon-nitrogen family YP_004604016.1 PFAM: Carbon-nitrogen hydrolase; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: ddf:DEFDS_0466 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region YP_004604017.1 PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC; InterPro IPR003646:IPR013247; KEGG: ddf:DEFDS_0465 hypothetical protein; PFAM: SH3, type 3; SMART: Bacterial SH3-like region; SPTR: Putative uncharacterized protein YP_004604018.1 PFAM: Bacterial SH3 domain; COGs: COG0012 GTPase probable translation factor; InterPro IPR002917:IPR013029:IPR004396; KEGG: ddf:DEFDS_0464 GTP-binding protein; PFAM: Protein of unknown function DUF933; GTP-binding protein, HSR1-related; SPTR: GTP-binding protein; TIGRFAM: Conserved hypothetical protein CHP00092 YP_004604019.1 PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF; COGs: COG3808 Inorganic pyrophosphatase; HAMAP: Pyrophosphate-energized proton pump; InterPro IPR004131; KEGG: ddf:DEFDS_0463 V-type H(+)-translocating pyrophosphatase; PFAM: Inorganic H+ pyrophosphatase; PRIAM: Inorganic diphosphatase; SPTR: Putative K(+)-stimulated pyrophosphate-energized sodium pump; TIGRFAM: Inorganic H+ pyrophosphatase YP_004604020.1 PFAM: Inorganic H+ pyrophosphatase; TIGRFAM: vacuolar-type H(+)-translocating pyrophosphatase; COGs: COG0193 Peptidyl-tRNA hydrolase; HAMAP: Peptidyl-tRNA hydrolase; InterPro IPR001328; KEGG: cni:Calni_0240 peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: Peptidyl-tRNA hydrolase YP_004604021.1 PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: ddf:DEFDS_0461 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase YP_004604022.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; InterPro IPR006204:IPR013750:IPR004424; KEGG: ddf:DEFDS_0460 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; SPTR: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004604023.1 PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; KEGG: dap:Dacet_0068 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604024.1 InterPro IPR019734:IPR001440:IPR013105; KEGG: cni:Calni_0236 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein YP_004604025.1 PFAM: Tetratricopeptide repeat; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482:IPR004549; KEGG: ddf:DEFDS_0457 acetyl-CoA carboxylase biotin carboxylase subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Acetyl-CoA carboxylase, biotin carboxylase subunit; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase YP_004604026.1 PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; COGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR000089:IPR001249; KEGG: ddf:DEFDS_0456 acetyl-CoA carboxylase biotin carboxyl carrier protein; PFAM: Biotin/lipoyl attachment; SPTR: Acetyl-CoA carboxylase, biotin carboxyl carrier protein; TIGRFAM: Acetyl-CoA biotin carboxyl carrier YP_004604027.1 PFAM: Biotin-requiring enzyme; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); HAMAP: Translation elongation factor P; InterPro IPR013185:IPR001059:IPR015365:IPR011768; KEGG: cni:Calni_0233 translation elongation factor P; PFAM: Elongation factor P, C-terminal; Translation elongation factor, KOW-like; Translation elongation factor P/YeiP, central; SPTR: Elongation factor P; TIGRFAM: Translation elongation factor P YP_004604028.1 PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: ddf:DEFDS_0454 X-Pro dipeptidase; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: X-Pro dipeptidase YP_004604029.1 PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0757 3-dehydroquinate dehydratase II; HAMAP: Dehydroquinase, class II; InterPro IPR001874; KEGG: ddf:DEFDS_0453 3-dehydroquinate dehydratase II; PFAM: Dehydroquinase, class II; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase II; TIGRFAM: Dehydroquinase, class II YP_004604030.1 PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II; InterPro IPR004942; KEGG: ddf:DEFDS_0452 hypothetical protein; PFAM: Dynein light chain-related; SPTR: Putative uncharacterized protein YP_004604031.1 PFAM: Roadblock/LC7 domain; InterPro IPR019734:IPR001440:IPR013105; KEGG: ddf:DEFDS_0451 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Putative uncharacterized protein YP_004604032.1 COGs: COG0337 3-dehydroquinate synthetase; HAMAP: 3-dehydroquinate synthase; InterPro IPR002658:IPR016037; KEGG: cni:Calni_0228 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase AroB, subgroup YP_004604033.1 PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase; COGs: COG0703 Shikimate kinase; HAMAP: Shikimate kinase; InterPro IPR000623; KEGG: ddf:DEFDS_0449 shikimate kinase; PFAM: Shikimate kinase; PRIAM: Shikimate kinase; SPTR: Shikimate kinase YP_004604034.1 PFAM: Shikimate kinase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001460; KEGG: ddf:DEFDS_0448 hypothetical protein; PFAM: Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative uncharacterized protein YP_004604035.1 PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; HAMAP: Nucleoside-triphosphatase rdgB; InterPro IPR002637; KEGG: ddf:DEFDS_0447 nucleoside-triphosphatase; PFAM: Ham1-like protein; PRIAM: Nucleoside-triphosphatase; SPTR: Nucleoside-triphosphatase; TIGRFAM: Ham1-like protein YP_004604036.1 PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; COGs: COG0689 RNase PH; HAMAP: Ribonuclease phosphorolytic, bacterial-type; InterPro IPR001247:IPR015847:IPR002381; KEGG: ddf:DEFDS_0446 tRNA nucleotidyltransferase; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: Ribonuclease PH; TIGRFAM: Ribonuclease phosphorolytic, bacterial-type YP_004604037.1 PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH; InterPro IPR007712:IPR012753; KEGG: sde:Sde_2750 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: Plasmid stabilization system protein; TIGRFAM: Addiction module toxin, RelE/StbE YP_004604038.1 PFAM: Plasmid stabilisation system protein; InterPro IPR003756:IPR006442; KEGG: sde:Sde_2751 ATPase; SPTR: Putative uncharacterized protein; TIGRFAM: Prevent-host-death protein YP_004604039.1 PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; COGs: COG0606 ATPase with chaperone activity; InterPro IPR003593:IPR000523:IPR004482; KEGG: ddf:DEFDS_2092 Mg chelatase-related protein; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Mg chelatase-related protein; TIGRFAM: Mg chelatase-related protein YP_004604040.1 PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002142:IPR004635; KEGG: ddf:DEFDS_2093 signal peptide peptidase SppA; PFAM: Peptidase S49; SPTR: Signal peptide peptidase SppA; TIGRFAM: Peptidase S49, SppA YP_004604041.1 PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837; KEGG: ddf:DEFDS_2094 Ca2+:cation antiporter, CaCA family; PFAM: Sodium/calcium exchanger membrane region; SPTR: Ca2+:cation antiporter, CaCA family YP_004604042.1 PFAM: Sodium/calcium exchanger protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: dap:Dacet_2952 hydroxymethylbutenyl pyrophosphate reductase; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: Hydroxymethylbutenyl pyrophosphate reductase YP_004604043.1 PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1; COGs: COG0761 Penicillin tolerance protein; HAMAP: LytB protein; InterPro IPR003451; KEGG: ddf:DEFDS_2096 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: LytB protein YP_004604044.1 PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR000623:IPR011994:IPR003136; KEGG: cni:Calni_0093 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase YP_004604045.1 PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; HAMAP: 3-phosphoshikimate 1-carboxyvinyltransferase, subgroup; InterPro IPR001986:IPR006264; KEGG: cni:Calni_0092 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: 3-phosphoshikimate 1-carboxyvinyltransferase, core; PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase, subgroup YP_004604046.1 PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: ddf:DEFDS_2099 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase YP_004604047.1 PFAM: Prephenate dehydrogenase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: ddf:DEFDS_2100 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 YP_004604048.1 PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR004839:IPR005861; KEGG: cni:Calni_0089 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: Histidinol-phosphate aminotransferase YP_004604049.1 PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0077 Prephenate dehydratase; InterPro IPR020822:IPR001086:IPR002912:IPR010957; KEGG: cni:Calni_0088 chorismate mutase; prephenate dehydratase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SPTR: Chorismate mutase; prephenate dehydratase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain YP_004604050.1 PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of gram positive AroA protein; chorismate mutase domain of proteobacterial P-protein, clade 2; KEGG: cni:Calni_0584 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604051.1 PFAM: Sporulation and spore germination; COGs: COG0655 Multimeric flavodoxin WrbA; HAMAP: Flavoprotein wrbA; InterPro IPR008254:IPR010089; KEGG: glo:Glov_0105 TrpR binding protein WrbA; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavoprotein wrbA; TIGRFAM: Flavoprotein WrbA YP_004604052.1 PFAM: NADPH-dependent FMN reductase; TIGRFAM: NAD(P)H:quinone oxidoreductase, type IV; COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: ddf:DEFDS_1568 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin YP_004604053.1 PFAM: Rubrerythrin; InterPro IPR000297; KEGG: cni:Calni_0648 ppic-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase YP_004604054.1 PFAM: PPIC-type PPIASE domain; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604055.1 PFAM: Transposase DDE domain; COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: ddf:DEFDS_0404 phosphate transport system regulator; PFAM: PhoU; SPTR: Phosphate transport system regulator; TIGRFAM: PhoU YP_004604056.1 PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cni:Calni_1570 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged helix family YP_004604057.1 PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: dap:Dacet_1228 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Integral membrane sensor signal transduction histidine kinase YP_004604058.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752:IPR000086:IPR003710; KEGG: ddf:DEFDS_2126 hypothetical protein; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal; Ketopantoate reductase ApbA/PanE, C-terminal; NUDIX hydrolase domain; PRIAM: 2-dehydropantoate 2-reductase; SPTR: Putative uncharacterized protein; TIGRFAM: Ketopantoate reductase ApbA/PanE YP_004604059.1 PFAM: Ketopantoate reductase PanE/ApbA; NUDIX domain; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR013093:IPR 019489; KEGG: ddf:DEFDS_2127 ATP-dependent Clp protease ATP-binding subunit ClpC; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpC YP_004604060.1 PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); COGs: COG2716 Glycine cleavage system regulatory protein; InterPro IPR002912; KEGG: ddf:DEFDS_2129 glycine cleavage system transcriptional repressor; PFAM: Amino acid-binding ACT; SPTR: Glycine cleavage system transcriptional repressor YP_004604061.1 PFAM: ACT domain; COGs: COG0242 N-formylmethionyl-tRNA deformylase; HAMAP: Formylmethionine deformylase; InterPro IPR000181; KEGG: ddf:DEFDS_2130 polypeptide deformylase; PFAM: Formylmethionine deformylase; PRIAM: Peptide deformylase; SPTR: Peptide deformylase 2; TIGRFAM: Formylmethionine deformylase YP_004604062.1 PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: cni:Calni_0206 D-isomer specific 2-hydroxyacid dehydrogenase nad-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Glyoxylate reductase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein YP_004604063.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004604064.1 PFAM: Uncharacterised protein family (UPF0153); COGs: COG1484 DNA replication protein; InterPro IPR002611; KEGG: ere:EUBREC_3222 possible transposase; PFAM: IstB-like ATP-binding protein; SPTR: DNA replication protein YP_004604065.1 PFAM: IstB-like ATP binding protein; IstB-like ATP binding N-terminal; This gene is disrupted by insertion of repetitive element; manually curated YP_004604066.1 PFAM: Transposase domain (DUF772); manually curated YP_004604067.1 PFAM: Transcriptional Coactivator p15 (PC4) YP_004604068.1 COGs: COG3091 conserved hypothetical protein; InterPro IPR006640:IPR005622; KEGG: cni:Calni_0195 hypothetical protein; SMART: Protein of unknown function SprT; SPTR: Putative uncharacterized protein YP_004604069.1 PFAM: SprT-like family YP_004604070.1 PFAM: Protein of unknown function (DUF2283); KEGG: cli:Clim_0720 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604072.1 InterPro IPR018649; KEGG: ddf:DEFDS_0309 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein YP_004604073.1 PFAM: Predicted membrane protein (DUF2078); KEGG: ddf:DEFDS_0913 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604074.1 PFAM: Protein of unknown function (DUF2874); InterPro IPR019020; KEGG: ppr:PBPRB0283 hypothetical protein; PFAM: Cytochrome c-552/DMSO reductase-like, haem-binding domain; SPTR: Putative uncharacterized protein YP_004604075.1 PFAM: Ethylbenzene dehydrogenase; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: response regulator receiver; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver YP_004604076.1 PFAM: Response regulator receiver domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594; KEGG: ATPase ATP-binding domain-containing protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: ATP-binding region ATPase domain protein YP_004604077.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: fnu:FN1352 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004604078.1 PFAM: ABC transporter; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: yen:YE2493 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Raw score 9.02 YP_004604079.1 PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: clo:HMPREF0868_0236 efflux ABC transporter permease; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Permease domain protein YP_004604080.1 PFAM: Predicted permease; COGs: COG4393 membrane protein; InterPro IPR018758; KEGG: tde:TDE1512 hypothetical protein; PFAM: Protein of unknown function DUF2318, membrane; SPTR: Membrane protein, putative YP_004604081.1 PFAM: Predicted membrane protein (DUF2318); COGs: COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport; InterPro IPR018470; KEGG: yen:YE2496 hypothetical protein; PFAM: Ferrous iron transport protein, bacterial; SPTR: Membrane antigen YP_004604082.1 PFAM: Fe2+ transport protein; COGs: COG0672 High-affinity Fe2+/Pb2+ permease; InterPro IPR004923; KEGG: cko:CKO_02057 hypothetical protein; PFAM: Iron permease FTR1; SPTR: Putative iron permease YP_004604083.1 PFAM: Iron permease FTR1 family; TIGRFAM: FTR1 family protein; KEGG: glo:Glov_1973 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604084.1 COGs: COG2270 Permease of the major facilitator superfamily; InterPro IPR011701; KEGG: sfu:Sfum_3450 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1 YP_004604085.1 PFAM: Vacuole effluxer Atg22 like; InterPro IPR000182; KEGG: hse:Hsero_1858 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase protein YP_004604086.1 PFAM: Acetyltransferase (GNAT) family; KEGG: hypothetical protein; SPTR: Putative uncharacterized protein YP_004604087.1 PFAM: Protein required for attachment to host cells; manually curated YP_004604088.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR014188:IPR013154:IPR013149; KEGG: amc:MADE_01969 alcohol dehydrogenase, zinc-containing; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase, zinc-containing; TIGRFAM: Quinone oxidoreductase putative, YhdH/YhfP YP_004604089.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family; KEGG: drt:Dret_1468 anti-ECFsigma factor, ChrR; SPTR: Anti-ECFsigma factor, ChrR YP_004604090.1 InterPro IPR000620; KEGG: ddf:DEFDS_0955 drug/metabolite transporter DME family; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Drug/metabolite transporter, DME family YP_004604091.1 PFAM: EamA-like transporter family YP_004604092.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2062); COGs: COG0466 ATP-dependent Lon protease; InterProIPR004815:IPR003111:IPR003593:IPR003959:IPR 008269; KEGG: ddf:DEFDS_1706 ATP-dependent Lon protease; PFAM: Peptidase S16, lon C-terminal; Peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: Peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: Peptidase S16, ATP-dependent protease La YP_004604093.1 PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ddf:DEFDS_1707 small heat shock protein, class I; PFAM: Heat shock protein Hsp20; SPTR: Small heat shock protein, class I YP_004604094.1 PFAM: Hsp20/alpha crystallin family; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005771:IPR005835; KEGG: cni:Calni_1635 udp-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UDP-glucose pyrophosphorylase; TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type YP_004604095.1 PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: ddf:DEFDS_1709 hypothetical protein; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; SPTR: Putative uncharacterized protein YP_004604096.1 PFAM: Memo-like protein; KEGG: dap:Dacet_1841 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604097.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050:IPR006638:IPR007197; KEGG: ddf:DEFDS_1711 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: putative menaquinone biosynthesis protein; FO synthase, subunit 2 YP_004604098.1 PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily; COGs: COG2206 HD-GYP domain; InterPro IPR001789:IPR003607:IPR006674; KEGG: ddf:DEFDS_1712 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Signal transduction response regulator, receiver region; Metal-dependent phosphohydrolase, HD region; SPTR: Putative uncharacterized protein YP_004604099.1 PFAM: HD domain; Response regulator receiver domain; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: cni:Calni_0537 heat shock protein DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein YP_004604100.1 PFAM: DnaJ domain YP_004604101.1 COGs: COG2871 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrF; InterPro IPR010205:IPR001041:IPR008333:IPR001433; KEGG: ddf:DEFDS_1913 Na(+)-translocating NADH-quinone reductase subunit F; PFAM: Oxidoreductase FAD/NAD(P)-binding; Ferredoxin; Oxidoreductase FAD-binding region; PRIAM: Phenol 2-monooxygenase; SPTR: Na(+)-translocating NADH-quinone reductase subunit F; TIGRFAM: NADH-quinone reductase, Na(+)-translocating, F subunit YP_004604102.1 PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit; COGs: COG2209 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrE; HAMAP: Na(+)-translocating NADH-quinone reductase subunit E; InterPro IPR010967:IPR003667; KEGG: ddf:DEFDS_1914 Na(+)-translocating NADH-quinone reductase subunit E; PFAM: Electron transport complex, Rnf/Nqr; SPTR: Na(+)-translocating NADH-quinone reductase subunit E; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit YP_004604103.1 PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit; COGs: COG1347 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrD; InterPro IPR011292:IPR003667; KEGG: ddf:DEFDS_1915 Na(+)-translocating NADH-quinone reductase subunit D; PFAM: Electron transport complex, Rnf/Nqr; SPTR: Na(+)-translocating NADH-quinone reductase subunit D; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit YP_004604104.1 PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit; COGs: COG2869 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrC; InterPro IPR010204:IPR007329; KEGG: dap:Dacet_2020 NADH:ubiquinone oxidoreductase, subunit C; PFAM: FMN-binding; SPTR: NADH:ubiquinone oxidoreductase, subunit C; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit YP_004604105.1 PFAM: FMN-binding domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; COGs: COG1805 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrB; InterPro IPR010966:IPR004338; KEGG: dap:Dacet_2021 NADH:ubiquinone oxidoreductase, subunit B; PFAM: NADH-quinone reductase NQR2/RnfD; SPTR: NADH:ubiquinone oxidoreductase, subunit B; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit YP_004604106.1 PFAM: NQR2, RnfD, RnfE family; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit; COGs: COG1726 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrA; HAMAP: Na(+)-translocating NADH-quinone reductase subunit A; InterPro IPR008703; KEGG: ilo:IL1050 Na(+)-translocating NADH-quinone reductase subunit A; PFAM: Na-translocating NADH-quinone reductase subunit A; SPTR: Na(+)-translocating NADH-quinone reductase subunit A; TIGRFAM: Na-translocating NADH-quinone reductase subunit A YP_004604107.1 PFAM: Na(+)-translocating NADH-quinone reductase subunit A (NQRA); NQRA C-terminal domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit YP_004604108.1 COGs: COG4584 Transposase and inactivated derivatives; KEGG: toc:Toce_1959 integrase catalytic region; SPTR: Integrase catalytic region YP_004604109.1 PFAM: Integrase core domain; COGs: COG1484 DNA replication protein; InterPro IPR003593:IPR002611; KEGG: toc:Toce_0299 IstB domain protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core; SPTR: IstB domain protein ATP-binding protein YP_004604110.1 PFAM: IstB-like ATP binding protein; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604111.1 COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004604112.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: ddf:DEFDS_0280 transposase IS4 family; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604113.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG1832 CoA-binding protein; InterPro IPR003781; KEGG: cni:Calni_0337 CoA-binding domain protein; PFAM: CoA-binding; SPTR: CoA-binding domain protein YP_004604114.1 PFAM: CoA binding domain; COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: ddf:DEFDS_1021 carbamoylphosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoylphosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit YP_004604115.1 PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: ddf:DEFDS_1020 aminodeoxychorismate lyase; PFAM: Uncharacterised protein family YceG-like; SPTR: Aminodeoxychorismate lyase; TIGRFAM: Uncharacterised protein family YceG-like YP_004604116.1 PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family; manually curated YP_004604117.1 PFAM: Transposase DDE domain; Transposase domain (DUF772) YP_004604118.1 COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: mac:MA2579 transposase; PFAM: Integrase, catalytic core; SPTR: Transposase, IS21 YP_004604119.1 PFAM: Integrase core domain YP_004604120.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase beta domain protein region YP_004604121.1 PFAM: Nucleotidyltransferase domain; InterPro IPR011462; KEGG: pca:Pcar_2264 transposase and inactivated derivatives; SPTR: Putative uncharacterized protein YP_004604122.1 PFAM: Transposase IS200 like; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604123.1 PFAM: Transposase DDE domain; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: cni:Calni_1143 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region YP_004604124.1 PFAM: Glycosyl transferase family 4; manually curated YP_004604125.1 PFAM: Transposase domain (DUF772); manually curated YP_004604126.1 PFAM: Transposase DDE domain; manually curated YP_004604127.1 PFAM: IstB-like ATP binding protein; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: msv:Mesil_3173 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604128.1 PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604129.1 PFAM: Transposase DDE domain; manually curated YP_004604130.1 PFAM: Aldehyde dehydrogenase family; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: hna:Hneap_2201 peptidase M24; PFAM: Creatinase; Peptidase M24, structural domain; SPTR: Peptidase M24 YP_004604131.1 PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR004637:IPR005814; KEGG: hna:Hneap_2200 2,4-diaminobutyrate 4-transaminase; PFAM: Aminotransferase class-III; PRIAM: Diaminobutyrate--2-oxoglutarate transaminase; SPTR: Diaminobutyrate--2-oxoglutarate transaminase; TIGRFAM: Diaminobutyrate-2-oxoglutarate transaminase YP_004604132.1 PFAM: Aminotransferase class-III; TIGRFAM: 2,4-diaminobutyrate 4-transaminases; diaminobutyrate--2-oxoglutarate aminotransferase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168:IPR002933:IPR011650; KEGG: ant:Arnit_1214 amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Hippurate hydrolase; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase YP_004604133.1 PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR011822:IPR003726:IPR000489:IPR003759:IPR 006158:IPR004223; KEGG: ddf:DEFDS_1683 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding; Vitamin B12 dependent methionine synthase, activation region; PRIAM: Methionine synthase; SPTR: 5-methyltetrahydrofolate--homocysteine methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase YP_004604134.1 PFAM: Pterin binding enzyme; Vitamin B12 dependent methionine synthase, activation domain; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR014343:IPR003593:IPR003439; KEGG: rhi:NGR_a01510 probable amino-acid ABC transporter ATP-binding protein y4tH; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Probable amino-acid ABC transporter ATP-binding protein y4tH; TIGRFAM: Ectoine/hydroxyectoine ABC transporter, ATP-binding protein YP_004604135.1 PFAM: ABC transporter; TIGRFAM: ectoine/hydroxyectoine ABC transporter, ATP-binding protein; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR014341:IPR010065:IPR000515; KEGG: rhi:NGR_a01520 probable amino-acid ABC transporter permease y4tG; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Probable amino-acid ABC transporter permease protein y4tG; TIGRFAM: Ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_004604136.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; ectoine/hydroxyectoine ABC transporter, permease protein EhuD; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR014342:IPR010065:IPR000515; KEGG: rhi:NGR_a01530 probable amino-acid ABC transporter permease y4tF; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Probable amino-acid ABC transporter permease protein y4tF; TIGRFAM: Ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_004604137.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; ectoine/hydroxyectoine ABC transporter, permease protein EhuC; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR014337:IPR001638; KEGG: rhi:NGR_a01540 probable periplasmic amino-acid binding protein y4tE of ABC-transporter; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; SPTR: Probable amino-acid ABC transporter periplasmic-binding protein y4tE; TIGRFAM: Ectoine/hydroxyEctoine ABC transporter solute-binding protein YP_004604138.1 PFAM: Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: ectoine/hydroxyectoine ABC transporter solute-binding protein; COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: ddf:DEFDS_0114 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Putative uncharacterized protein YP_004604139.1 PFAM: Protein of unknown function (DUF1015); COGs: COG0162 Tyrosyl-tRNA synthetase; HAMAP: Tyrosyl-tRNA synthetase; InterPro IPR002307:IPR002305; KEGG: ddf:DEFDS_0113 tyrosyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial YP_004604140.1 PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase; COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR010627:IPR000045; KEGG: ddf:DEFDS_0112 type IV prepilin peptidase; PFAM: Peptidase A24A, N-terminal; Peptidase A24A, prepilin type IV; PRIAM: Prepilin peptidase; SPTR: Type IV prepilin peptidase YP_004604141.1 PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase family; COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: ddf:DEFDS_0110 hypothetical protein; PFAM: Protein of unknown function DUF1009; SPTR: Putative uncharacterized protein YP_004604142.1 PFAM: Protein of unknown function (DUF1009); COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: cni:Calni_0305 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; SPTR: Oxidoreductase domain protein YP_004604143.1 PFAM: Oxidoreductase family, NAD-binding Rossmann fold; COGs: COG1043 Acyl-(acyl carrier protein); InterPro IPR010137:IPR001451; KEGG: cni:Calni_0304 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineo-acyltransferase; PRIAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:Acyl-(Acyl-carrier-protein)--UDP-N-acetylgluco samineO-acyltransferase; TIGRFAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgl ucosamineO-acyltransferase YP_004604144.1 PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; HAMAP: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; InterPro IPR010084:IPR013114; KEGG: ddf:DEFDS_0107 3R-hydroxymyristoyl ACP dehydrase; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; TIGRFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ YP_004604145.1 PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ; COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); HAMAP: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; InterPro IPR007691:IPR001451; KEGG: cni:Calni_0302 udp-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; PFAM: Bacterial transferase hexapeptide repeat; SPTR: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_004604146.1 PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; InterPro IPR005632; KEGG: ddf:DEFDS_0105 outer membrane protein OmpH; PFAM: Outer membrane chaperone Skp (OmpH); SPTR: Outer membrane protein OmpH YP_004604147.1 PFAM: Outer membrane protein (OmpH-like); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474:IPR010827:IPR000184; KEGG: ddf:DEFDS_0104 hypothetical protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Putative uncharacterized protein; TIGRFAM: Outer membrane assembly protein, YaeT YP_004604148.1 PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein; COGs: COG0040 ATP phosphoribosyltransferase; HAMAP: ATP phosphoribosyltransferase; InterPro IPR013820; KEGG: cni:Calni_0299 ATP phosphoribosyltransferase (homohexameric); PFAM: ATP phosphoribosyltransferase, catalytic region; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, catalytic region YP_004604149.1 PFAM: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase; COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; HAMAP: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; InterPro IPR005750:IPR001986; KEGG: cni:Calni_0298 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: 3-phosphoshikimate 1-carboxyvinyltransferase, core; PRIAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004604150.1 PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR004556:IPR019874:IPR013217; KEGG: ddf:DEFDS_0101 modification methylase HemK family; PFAM: Methyltransferase type 12; SPTR: Modification methylase, HemK family; TIGRFAM: Protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK YP_004604151.1 PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific; COGs: COG0216 Protein chain release factor A; HAMAP: Peptide chain release factor 1; InterPro IPR004373:IPR005139:IPR000352; KEGG: ddf:DEFDS_0100 peptide chain release factor RF-1; PFAM: Class I peptide chain release factor; Peptide chain release factor; SPTR: Peptide chain release factor 1; TIGRFAM: Peptide chain release factor 1 YP_004604152.1 PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1; COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: cni:Calni_0295 hypothetical protein; PFAM: Protein of unknown function DUF1385; SPTR: Putative uncharacterized protein YP_004604153.1 PFAM: Protein of unknown function (DUF1385); COGs: COG1351 alternative thymidylate synthase; HAMAP: Thymidylate synthase thyX; InterPro IPR003669; KEGG: cni:Calni_0294 thymidylate synthase (fad); PFAM: Thymidylate synthase ThyX; SPTR: Thymidylate synthase thyX; TIGRFAM: Thymidylate synthase ThyX YP_004604154.1 PFAM: Thymidylate synthase complementing protein; TIGRFAM: thymidylate synthase, flavin-dependent; COGs: COG0254 Ribosomal protein L31; HAMAP: 50S ribosomal protein L31; InterPro IPR002150; KEGG: ddf:DEFDS_0097 50S ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: Ribosomal protein L31 YP_004604155.1 PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31; COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: ddf:DEFDS_0248 30S ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9 YP_004604156.1 PFAM: Ribosomal protein S9/S16; COGs: COG0102 Ribosomal protein L13; InterPro IPR005823:IPR005822; KEGG: ddf:DEFDS_0249 50S ribosomal protein L13; PFAM: Ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: Ribosomal protein L13, bacterial-type YP_004604157.1 PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type; COGs: COG0335 Ribosomal protein L19; HAMAP: Ribosomal protein L19; InterPro IPR001857; KEGG: cni:Calni_2013 LSU ribosomal protein l19p; PFAM: Ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: Ribosomal protein L19 YP_004604158.1 PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type; COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; HAMAP: tRNA (guanine-N1-)-methyltransferase, bacteria; InterPro IPR002649:IPR016009:IPR019230; KEGG: ddf:DEFDS_0251 tRNA (guanine-N(1)-)-methyltransferase; PFAM: Protein of unknown function DUF2168; tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1-)-methyltransferase, bacteria YP_004604159.1 PFAM: tRNA (Guanine-1)-methyltransferase; Uncharacterized protein conserved in bacteria (DUF2168); TIGRFAM: tRNA (guanine-N1)-methyltransferase; COGs: COG0806 RimM protein required for 16S rRNA processing; HAMAP: 16S rRNA processing protein RimM; InterPro IPR011961:IPR002676:IPR007903; KEGG: cni:Calni_2011 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel; SPTR: Ribosome maturation factor rimM; TIGRFAM: 16S rRNA processing protein RimM YP_004604160.1 PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM; COGs: COG1837 RNA-binding protein (contains KH domain); HAMAP: Uncharacterised protein family UPF0109, bacterial; InterPro IPR020627; KEGG: ddf:DEFDS_0253 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604161.1 PFAM: KH domain; COGs: COG0228 Ribosomal protein S16; HAMAP: Ribosomal protein S16; InterPro IPR000307; KEGG: cni:Calni_2009 SSU ribosomal protein s16p; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: Ribosomal protein S16 YP_004604162.1 PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; COGs: COG0541 Signal recognition particle GTPase; InterProIPR004780:IPR003593:IPR013822:IPR000897:IPR 004125; KEGG: ddf:DEFDS_0255 signal recognition particle protein; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; Signal recognition particle, SRP54 subunit, M-domain; SMART: ATPase, AAA+ type, core; SPTR: Signal recognition particle protein; TIGRFAM: Signal recognition particle, SRP YP_004604163.1 PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein; COGs: COG0237 Dephospho-CoA kinase; HAMAP: Dephospho-CoA kinase; InterPro IPR001977; KEGG: ddf:DEFDS_0315 dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; TIGRFAM: Dephospho-CoA kinase YP_004604164.1 PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; InterPro IPR005358; KEGG: ddf:DEFDS_0314 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein YP_004604165.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: ddf:DEFDS_0313 fumarylacetoacetate hydrolase family protein; PFAM: Fumarylacetoacetase, C-terminal-like; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: Fumarylacetoacetate hydrolase family protein YP_004604166.1 PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR006675:IPR003607:IPR002646:IPR006674; KEGG: ddf:DEFDS_0057 tRNA nucleotidyltransferase (CCA-adding enzyme); PFAM: Polynucleotide adenylyltransferase region; Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: tRNA nucleotidyltransferase (CCA-adding enzyme); TIGRFAM: HDIG YP_004604167.1 PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: cni:Calni_1754 phosphodiesterase, mj0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025 YP_004604168.1 PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family; COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR006076; KEGG: ddf:DEFDS_0059 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase YP_004604169.1 PFAM: FAD dependent oxidoreductase; KEGG: cni:Calni_0426 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604170.1 InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604171.1 PFAM: Transposase DDE domain; COGs: COG1158 Transcription termination factor; InterProIPR004665:IPR011129:IPR003593:IPR011112:IPR 011113:IPR000194; KEGG: ddf:DEFDS_0096 transcription termination factor Rho; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; Rho termination factor, RNA-binding; Rho termination factor, N-terminal; SMART: Cold shock protein; ATPase, AAA+ type, core; SPTR: Transcription termination factor Rho; TIGRFAM: Transcription termination factor Rho YP_004604172.1 PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho; InterPro IPR015414; KEGG: dol:Dole_2781 SNARE associated Golgi protein; PFAM: SNARE associated Golgi protein; SPTR: Putative uncharacterized protein YP_004604173.1 PFAM: SNARE associated Golgi protein; KEGG: drt:Dret_2127 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604174.1 COGs: COG1687 branched-chain amino acid permease (azaleucine resistance); InterPro IPR008407; KEGG: sdl:Sdel_1541 branched-chain amino acid transport; PFAM: Branched-chain amino acid transport; SPTR: Branched-chain amino acid transport YP_004604175.1 PFAM: Branched-chain amino acid transport protein (AzlD); COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: wsu:WS1320 hypothetical protein; PFAM: AzlC-like; SPTR: Putative uncharacterized protein YP_004604176.1 PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604177.1 PFAM: Transposase DDE domain YP_004604178.1 PFAM: Chorismate synthase; TIGRFAM: chorismate synthase; COGs: COG1993 conserved hypothetical protein; InterPro IPR003793; KEGG: ddf:DEFDS_0610 hypothetical protein; PFAM: Protein of unknown function DUF190; SPTR: Putative uncharacterized protein YP_004604179.1 PFAM: Uncharacterized ACR, COG1993; COGs: COG0239 Integral membrane protein possibly involved in chromosome condensation; HAMAP: CrcB-like protein; InterPro IPR003691; KEGG: dap:Dacet_1834 CrcB protein; PFAM: Camphor resistance CrcB protein; SPTR: Protein CrcB homolog; TIGRFAM: Camphor resistance CrcB protein YP_004604180.1 PFAM: CrcB-like protein; TIGRFAM: crcB protein; KEGG: ddf:DEFDS_0608 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated YP_004604181.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR014187:IPR013154; KEGG: ddf:DEFDS_1932 alcohol dehydrogenase zinc-binding; PFAM: Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase, zinc-binding; TIGRFAM: Alcohol dehydrogenase, zinc-binding type 2 YP_004604182.1 PFAM: Alcohol dehydrogenase GroES-like domain; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: dba:Dbac_1690 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-dependent synthetase and ligase YP_004604183.1 PFAM: AMP-binding enzyme; COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: cni:Calni_0752 tRNA (adenine-58-n(1)-) methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: tRNA (Adenine-58-N(1)-) methyltransferase YP_004604184.1 PFAM: tRNA methyltransferase complex GCD14 subunit; COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004604185.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; InterPro IPR009875; PFAM: Type IV pilus assembly PilZ YP_004604186.1 PFAM: PilZ domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: dau:Daud_1728 putative PAS/PAC sensor protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Putative PAS/PAC sensor protein YP_004604187.1 PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; InterPro IPR010177; KEGG: ddf:DEFDS_0760 multiheme C-type cytochrome; PFAM: Doubled CXXCH motif; SPTR: Multiheme c-type cytochrome; TIGRFAM: Doubled CXXCH motif YP_004604188.1 PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain YP_004604189.1 InterPro IPR001258; KEGG: ddf:DEFDS_0759 hypothetical protein; PFAM: NHL repeat; SPTR: Putative uncharacterized protein YP_004604190.1 PFAM: NHL repeat; KEGG: ddf:DEFDS_0758 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604191.1 KEGG: ddf:DEFDS_0757 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604192.1 KEGG: ddf:DEFDS_0756 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004604193.1 PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain; KEGG: ddf:DEFDS_0755 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004604194.1 InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004604195.1 PFAM: Transposase domain (DUF772); KEGG: ddf:DEFDS_0754 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004604196.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: ddf:DEFDS_0752 two-component system, NtrC family, response regulator AtoC; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two-component system, NtrC family, response regulator AtoC YP_004604197.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ddf:DEFDS_0751 hypothetical protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Putative uncharacterized protein YP_004604198.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; InterPro IPR001258; KEGG: ddf:DEFDS_0750 hypothetical protein; PFAM: NHL repeat; SPTR: Putative uncharacterized protein YP_004604199.1 PFAM: NHL repeat; InterPro IPR010177; KEGG: ddf:DEFDS_0749 multiheme C-type cytochrome; PFAM: Doubled CXXCH motif; SPTR: Multiheme c-type cytochrome; TIGRFAM: Doubled CXXCH motif YP_004604200.1 PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain; KEGG: ddf:DEFDS_0748 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604201.1 InterPro IPR010177; KEGG: ddf:DEFDS_0747 multiheme C-type cytochrome; PFAM: Doubled CXXCH motif; SPTR: Multiheme c-type cytochrome; TIGRFAM: Doubled CXXCH motif YP_004604202.1 PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain; InterPro IPR010177; KEGG: ddf:DEFDS_0746 multiheme C-type cytochrome; PFAM: Doubled CXXCH motif; SPTR: Multiheme c-type cytochrome; TIGRFAM: Doubled CXXCH motif YP_004604203.1 PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain; InterPro IPR001258; KEGG: ddf:DEFDS_0745 hypothetical protein; PFAM: NHL repeat; SPTR: Putative uncharacterized protein YP_004604204.1 PFAM: NHL repeat; KEGG: ddf:DEFDS_0744 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004604205.1 KEGG: ddf:DEFDS_0743 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604206.1 PFAM: Cytochrome b(N-terminal)/b6/petB; KEGG: ddf:DEFDS_0742 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004604207.1 KEGG: ddf:DEFDS_0741 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome YP_004604208.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: ddf:DEFDS_0740 signal transduction response regulator; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PRIAM: Diguanylate kinase; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; SPTR: Signal transduction response regulator; TIGRFAM: Diguanylate cyclase, predicted YP_004604209.1 PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0526 Thiol-disulfide isomerase and thioredoxins; InterPro IPR000866; KEGG: ddf:DEFDS_1942 thioredoxin family protein; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Thioredoxin family protein YP_004604210.1 PFAM: AhpC/TSA family; COGs: COG1160 GTPase; HAMAP: GTP-binding, EngA; InterPro IPR016484:IPR005225:IPR002917; KEGG: ddf:DEFDS_1072 small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: GTP-binding, EngA; Small GTP-binding protein YP_004604211.1 PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain; COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR004527:IPR020058; KEGG: ddf:DEFDS_1071 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: Glutamate--tRNA ligase; SPTR: Glutamyl-tRNA synthetase; TIGRFAM: Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial YP_004604212.1 PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: cni:Calni_2046 response regulator receiver modulated diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted YP_004604213.1 PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890; KEGG: cni:Calni_0977 anthranilate synthase, component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, component I YP_004604214.1 PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR006221:IPR000991; KEGG: ddf:DEFDS_0439 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase YP_004604215.1 PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; COGs: COG0547 Anthranilate phosphoribosyltransferase; HAMAP: Anthranilate phosphoribosyl transferase; InterPro IPR005940:IPR017459:IPR000312; KEGG: cni:Calni_0979 anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: Anthranilate phosphoribosyl transferase YP_004604216.1 PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: cni:Calni_0980 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol-phosphate synthase YP_004604217.1 PFAM: Indole-3-glycerol phosphate synthase; COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: ddf:DEFDS_0442 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: N-(5'-phosphoribosyl)anthranilate isomerase YP_004604218.1 PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0133 Tryptophan synthase beta chain; HAMAP: Tryptophan synthase beta chain; InterPro IPR006654:IPR001926; KEGG: ddf:DEFDS_0443 tryptophan synthase subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain 1; TIGRFAM: Tryptophan synthase, beta chain YP_004604219.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit; COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR002028; KEGG: cni:Calni_0983 tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase, alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: Tryptophan synthase, alpha chain YP_004604220.1 PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit; KEGG: ddf:DEFDS_1681 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604221.1 PFAM: Nitrous oxide-stimulated promoter; KEGG: cni:Calni_0024 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604222.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cni:Calni_0023 abc transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein YP_004604223.1 PFAM: ABC transporter; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR003495; KEGG: cni:Calni_0022 cobalamin synthesis protein p47k; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Cobalamin synthesis protein P47K YP_004604224.1 PFAM: CobW/HypB/UreG, nucleotide-binding domain; COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR015077; KEGG: cni:Calni_0021 hypothetical protein; PFAM: Domain of unknown function DUF1858; SPTR: Putative uncharacterized protein YP_004604225.1 PFAM: Domain of unknown function (DUF1858); COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; HAMAP: Glycyl-tRNA synthetase, class IIc, alpha subunit; InterPro IPR002310; KEGG: ddf:DEFDS_0639 glycyl-tRNA synthetase subunit alpha; PFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit YP_004604226.1 PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit; COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: cni:Calni_0743 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase YP_004604227.1 PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168:IPR002933:IPR011650; KEGG: ddf:DEFDS_1806 N-acetyl-L-amino acid amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: N-acetyl-L-amino acid amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase YP_004604228.1 PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase; COGs: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; HAMAP: L-seryl-tRNA(Sec) selenium transferase; InterPro IPR004534:IPR018319; KEGG: ddf:DEFDS_0273 L-seryl-tRNA(Sec) selenium transferase; PFAM: Pyridoxal phosphate-dependent transferase; PRIAM: L-seryl-tRNA(Sec) selenium transferase; SPTR: L-seryl-tRNA(Sec) selenium transferase; TIGRFAM: L-seryl-tRNA selenium transferase YP_004604229.1 PFAM: L-seryl-tRNA selenium transferase; TIGRFAM: seryl-tRNA(sec) selenium transferase; COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR005225:IPR004535:IPR000795:IPR004161:IPR 015191; KEGG: ddf:DEFDS_0272 selenocysteine-specific translation elongation factor; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor SelB, winged helix, type 3; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: Translation elongation factor, selenocysteine-specific; Small GTP-binding protein YP_004604230.1 PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winged helix; TIGRFAM: selenocysteine-specific elongation factor SelB; small GTP-binding protein domain; This gene is disrupted by insertion of repetitive element; manually curated YP_004604231.1 PFAM: Transposase DDE domain; InterPro IPR007456; KEGG: dap:Dacet_0848 hypothetical protein; PFAM: Protein of unknown function DUF494; SPTR: Putative uncharacterized protein YP_004604232.1 PFAM: Protein of unknown function (DUF494); COGs: COG0550 Topoisomerase IA; InterProIPR005733:IPR006154:IPR003601:IPR003602:IPR 006171:IPR013497:IPR013498; KEGG: ddf:DEFDS_1803 DNA topoisomerase I; PFAM: DNA topoisomerase, type IA, central; Toprim domain; DNA topoisomerase, type IA, zn finger; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; SPTR: DNA topoisomerase I; TIGRFAM: DNA topoisomerase I, bacterial-type YP_004604233.1 PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial; COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; HAMAP:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferasetrmFO; InterPro IPR004417:IPR002218; KEGG: ddf:DEFDS_1802 glucose inhibited division protein A; PFAM: Glucose-inhibited division protein A-related; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferaseTrmFO; TIGRFAM:Methylenetetrahydrofolate--tRNA-(uracil-5-) -methyltransferase,TrmFO YP_004604234.1 PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase; COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: cni:Calni_1109 integrase family protein; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase xerC 2 YP_004604235.1 PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; COGs: COG0709 Selenophosphate synthase; InterPro IPR004536:IPR000728:IPR010918; KEGG: ddf:DEFDS_0345 selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; SPTR: Selenide, water dikinase; TIGRFAM: Selenide water dikinase YP_004604236.1 PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: selenium donor protein; InterPro IPR019870:IPR001455; KEGG: ddf:DEFDS_0344 hypothetical protein; PFAM: SirA-like; SPTR: Putative uncharacterized protein; TIGRFAM: SirA-related, selenium metabolism YP_004604237.1 PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ddf:DEFDS_0343 aminotransferase I and II; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase, I and II YP_004604238.1 PFAM: Aminotransferase class I and II; COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR003333; KEGG: ddf:DEFDS_1472 cyclopropane-fatty-acyl-phospholipid synthase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; PRIAM: Cyclopropane-fatty-acyl-phospholipid synthase; SPTR: Cyclopropane-fatty-acyl-phospholipid synthase YP_004604239.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: chu:CHU_0540 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: ArsR family bacterial regulatory protein YP_004604240.1 PFAM: Bacterial regulatory protein, arsR family; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: chu:CHU_1514 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; SPTR: Protein containing Methyltransferase type 11 domain YP_004604241.1 PFAM: Methyltransferase domain; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004604242.1 PFAM: Transposase domain (DUF772); COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: cni:Calni_0116 SNARE associated golgi protein-related protein; PFAM: SNARE associated Golgi protein; SPTR: SNARE associated Golgi protein-related protein YP_004604243.1 PFAM: SNARE associated Golgi protein; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099; KEGG: dap:Dacet_1398 pyridine nucleotide-disulfide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Pyridine nucleotide-disulfide oxidoreductase dimerization region YP_004604244.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; COGs: COG3222 conserved hypothetical protein; InterPro IPR018641; KEGG: gfo:GFO_3609 hypothetical protein; PFAM: Protein of unknown function DUF2064; SPTR: Putative uncharacterized protein YP_004604245.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2064); COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: noc:Noc_0586 UbiE/COQ5 methyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: UbiE/COQ5 methyltransferase; manually curated YP_004604246.1 PFAM: Methyltransferase domain; manually curated YP_004604247.1 PFAM: Glycosyl transferase family 2; InterPro IPR010181; KEGG: dap:Dacet_1415 C_GCAxxG_C_C family protein; PFAM: CGCAxxGCC motif; SPTR: C_GCAxxG_C_C family protein; TIGRFAM: CGCAxxGCC motif YP_004604248.1 PFAM: Putative redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR000014:IPR003593:IPR013767:IPR002078; KEGG: cni:Calni_1353 sigma54 specific transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; PAS fold; SMART: ATPase, AAA+ type, core; PAS; SPTR: Putative sigma54 specific transcriptional regulator; TIGRFAM: PAS YP_004604249.1 PFAM: Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4663 TRAP-type mannitol/chloroaromatic compound transport system periplasmic component; InterPro IPR018389; KEGG: cni:Calni_1350 extracellular solute-binding protein, family 7; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Extracellular solute-binding protein, family 7 YP_004604250.1 PFAM: Bacterial extracellular solute-binding protein, family 7; COGs: COG4665 TRAP-type mannitol/chloroaromatic compound transport system small permease component; InterPro IPR007387; KEGG: cni:Calni_1351 tripartite ATP-independent periplasmic transporter DctQ component; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Tripartite ATP-independent periplasmic transporter DctQ component YP_004604251.1 PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG4664 TRAP-type mannitol/chloroaromatic compound transport system large permease component; InterPro IPR004681:IPR010656; KEGG: cni:Calni_1352 trap dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit YP_004604252.1 PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: cni:Calni_1354 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase YP_004604253.1 PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR012792:IPR012791:IPR004165; KEGG: cni:Calni_1355 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; 3-oxoacid CoA-transferase, subunit A YP_004604254.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; 3-oxoacid CoA-transferase, A subunit; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR011294:IPR002198; KEGG: cni:Calni_1356 3-hydroxybutyrate dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-hydroxybutyrate dehydrogenase; SPTR: 3-hydroxybutyrate dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase YP_004604255.1 PFAM: short chain dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR001450; KEGG: dap:Dacet_0227 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004604256.1 PFAM: 4Fe-4S binding domain; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: cni:Calni_0511 DegT/DnrJ/eryc1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase YP_004604257.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG2121 conserved hypothetical protein; InterPro IPR007172; KEGG: ddf:DEFDS_0135 hypothetical protein; PFAM: Protein of unknown function DUF374; SPTR: Putative uncharacterized protein YP_004604258.1 PFAM: Domain of unknown function (DUF374); COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR007507; KEGG: cni:Calni_0509 three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; PFAM: Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal; SPTR: Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein YP_004604259.1 PFAM: 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: ddf:DEFDS_0137 lipid A biosynthesis lauroyl acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis lauroyl acyltransferase YP_004604260.1 PFAM: Bacterial lipid A biosynthesis acyltransferase; COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR006543:IPR006549:IPR005834; KEGG: cni:Calni_0507 histidinol-phosphate phosphatase family protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Histidinol-phosphate phosphatase family protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; Histidinol-phosphate phosphatase YP_004604261.1 PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family domain; COGs: COG0078 Ornithine carbamoyltransferase; HAMAP: Ornithine carbamoyltransferase; InterPro IPR002292:IPR006132:IPR006131; KEGG: ddf:DEFDS_1628 ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Ornithine carbamoyltransferase; SPTR: Ornithine carbamoyltransferase; TIGRFAM: Ornithine carbamoyltransferase YP_004604262.1 PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: ddf:DEFDS_1629 acetylornithine transaminase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine transaminase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase YP_004604263.1 PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; InterPro IPR001450; KEGG: cni:Calni_1000 hypothetical protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein YP_004604264.1 PFAM: 4Fe-4S binding domain; KEGG: cni:Calni_1001 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604265.1 COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: ddf:DEFDS_0690 hypothetical protein; PFAM: AMMECR1; SPTR: Putative uncharacterized protein; TIGRFAM: AMMECR1 YP_004604266.1 PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; KEGG: dps:DP2152 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604267.1 PFAM: Pyridoxamine 5'-phosphate oxidase; COGs: COG0225 Peptide methionine sulfoxide reductase; HAMAP: Peptide methionine sulfoxide reductase msrB; Peptide methionine sulphoxide reductase MsrA; InterPro IPR002569:IPR002579; KEGG: dat:HRM2_08740 MsrAB; PFAM: Peptide methionine sulphoxide reductase MsrA; Methionine sulphoxide reductase B; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: MsrAB; TIGRFAM: Methionine sulphoxide reductase B; Peptide methionine sulphoxide reductase MsrA; manually curated YP_004604268.1 PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604269.1 PFAM: Transposase DDE domain; manually curated YP_004604270.1 COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR006286:IPR002818; KEGG: cni:Calni_0548 intracellular protease, PfpI family; PFAM: ThiJ/PfpI; SPTR: Intracellular protease, PfpI family; TIGRFAM: Peptidase C56, PfpI YP_004604271.1 PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family; InterPro IPR002645; KEGG: dap:Dacet_2858 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist YP_004604272.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; InterPro IPR002645; KEGG: cni:Calni_0942 pbs lyase heat domain protein repeat-containing protein; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: PBS lyase HEAT domain protein repeat-containing protein YP_004604273.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit; HAMAP: ATP-dependent hsl protease ATP-binding subunit hslU; InterPro IPR004491:IPR003593:IPR013093; KEGG: ddf:DEFDS_2156 ATP-dependent protease HslVU, ATPase subunit HslU; PFAM: ATPase associated with various cellular activities, AAA-2; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent protease ATPase subunit HslU; TIGRFAM: Heat shock protein HslU YP_004604274.1 PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent protease HslVU, ATPase subunit; COGs: COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit; HAMAP: ATP-dependent protease hslV; InterPro IPR001353; KEGG: ddf:DEFDS_2155 ATP-dependent protease HslVU, peptidase subunit HslV; PFAM: Proteasome, subunit alpha/beta; SPTR: ATP-dependent protease subunit HslV; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit YP_004604275.1 PFAM: Proteasome subunit; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604276.1 PFAM: Transposase DDE domain; COGs: COG1067 ATP-dependent protease; InterPro IPR008269; KEGG: rxy:Rxyl_1929 ATP-dependent protease; PFAM: Peptidase S16, lon C-terminal; SPTR: ATP-dependent protease, putative YP_004604277.1 PFAM: Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; COGs: COG0326 Molecular chaperone HSP90 family; HAMAP: Chaperone protein htpG; InterPro IPR001404:IPR003594:IPR020576; KEGG: cni:Calni_0147 heat shock protein HSP90; PFAM: Heat shock protein Hsp90, C-terminal; ATP-binding region, ATPase-like; SPTR: Chaperone protein htpG YP_004604278.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; HAMAP: tRNA-specific 2-thiouridylase; InterPro IPR004506:IPR018318; KEGG: ddf:DEFDS_1156 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase-like; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA-specific 2-thiouridylase YP_004604279.1 PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604280.1 PFAM: Transposase DDE domain; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ddf:DEFDS_1153 hypothetical protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: Putative uncharacterized protein YP_004604281.1 PFAM: NOL1/NOP2/sun family; InterPro IPR013216; KEGG: cni:Calni_1990 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11 YP_004604282.1 PFAM: Methyltransferase domain; manually curated YP_004604283.1 PFAM: General secretion pathway protein K; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: ddf:DEFDS_1437 Sir2 family transcriptional regulator; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Transcriptional regulator, Sir2 family YP_004604284.1 PFAM: Sir2 family; KEGG: dap:Dacet_2751 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604285.1 PFAM: Protein of unknown function (DUF2860); InterPro IPR013429; KEGG: ddf:DEFDS_1611 hypothetical protein; PFAM: Regulatory protein, FmdB, putative; SPTR: Putative uncharacterized protein; TIGRFAM: Regulatory protein, FmdB, putative YP_004604286.1 PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family; COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR001450; KEGG: toc:Toce_2222 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004604287.1 PFAM: 4Fe-4S binding domain; InterPro IPR010181; KEGG: mpd:MCP_2169 hypothetical protein; PFAM: CGCAxxGCC motif; SPTR: Putative uncharacterized protein; TIGRFAM: CGCAxxGCC motif YP_004604288.1 PFAM: Putative redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein YP_004604289.1 PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; HAMAP: Methylthioribose-1-phosphate isomerase; InterPro IPR005251:IPR011559:IPR000649; KEGG: ddf:DEFDS_0061 translation initiation factor IF-2B; PFAM: Initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: Translation initiation factor IF-2B; TIGRFAM: Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase; Initiation factor 2B alpha/beta/delta YP_004604290.1 PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-methyl-5-thioribose-1-phosphate isomerase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: ddf:DEFDS_0060 hypothetical protein; PFAM: NADPH-dependent FMN reductase; SPTR: Putative uncharacterized protein YP_004604291.1 PFAM: NADPH-dependent FMN reductase; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: cni:Calni_0431 peptidase M24; PFAM: Peptidase M24, structural domain; SPTR: Peptidase M24 YP_004604292.1 PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284:IPR009042:IPR007627:IPR007624:IPR 007630; KEGG: dap:Dacet_0446 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70 YP_004604293.1 PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005268:IPR005269; KEGG: ddf:DEFDS_0259 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00725 YP_004604294.1 PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: cni:Calni_0623 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2 YP_004604295.1 PFAM: Glycosyl transferase family 2; COGs: COG1522 Transcriptional regulators; InterPro IPR019888:IPR019887; KEGG: dap:Dacet_2404 transcriptional regulator, AsnC family; PFAM: Transcription regulator, AsnC-type, C-terminal; SMART: Transcription regulator, AsnC-type; SPTR: Transcriptional regulator, AsnC family YP_004604296.1 PFAM: AsnC family; COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003651; KEGG: cni:Calni_0621 DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD domain; SPTR: DNA-(Apurinic or apyrimidinic site) lyase YP_004604297.1 PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: endonuclease III; KEGG: ddf:DEFDS_1866 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604298.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: ddf:DEFDS_2167 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase YP_004604299.1 PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase NifS; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cni:Calni_0618 transcriptional regulator, badm/rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2 YP_004604300.1 PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein; COGs: COG1045 Serine acetyltransferase; InterPro IPR005881:IPR001451; KEGG: ddf:DEFDS_2169 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase YP_004604301.1 PFAM: Serine acetyltransferase, N-terminal; TIGRFAM: serine O-acetyltransferase; InterPro IPR001450; KEGG: ddf:DEFDS_2170 4Fe-4S ferredoxin; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin YP_004604302.1 PFAM: 4Fe-4S binding domain; KEGG: ddf:DEFDS_2171 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604303.1 InterPro IPR000086; KEGG: ddf:DEFDS_2172 phosphohydrolase MutT/NUDIX family; PFAM: NUDIX hydrolase domain; SPTR: Phosphohydrolase, MutT/NUDIX family YP_004604304.1 PFAM: NUDIX domain; COGs: COG2021 Homoserine acetyltransferase; HAMAP: Homoserine O-acetyltransferase; InterPro IPR006296:IPR000073; KEGG: ddf:DEFDS_1867 homoserine O-acetyltransferase; PFAM: Alpha/beta hydrolase fold-1; PRIAM: Homoserine O-acetyltransferase; SPTR: Homoserine O-acetyltransferase; TIGRFAM: Homoserine O-acetyltransferase YP_004604305.1 PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase; InterPro IPR013216; KEGG: ddf:DEFDS_1868 methyltransferase UbiE/COQ5 family; PFAM: Methyltransferase type 11; SPTR: Methyltransferase, UbiE/COQ5 family YP_004604306.1 PFAM: Methyltransferase domain; COGs: COG4619 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ddf:DEFDS_1869 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein YP_004604307.1 PFAM: ABC transporter; COGs: COG0390 ABC-type uncharacterized transport system permease component; InterPro IPR005226; KEGG: ddf:DEFDS_1870 ABC transporter permease; PFAM: Conserved hypothetical protein CHP00245; SPTR: ABC transporter, permease; TIGRFAM: Conserved hypothetical protein CHP00245 YP_004604308.1 PFAM: Uncharacterised protein family (UPF0014); TIGRFAM: TIGR00245 family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR000644; KEGG: ddf:DEFDS_1871 chloride channel protein, CIC family; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SPTR: Chloride channel protein, CIC family YP_004604309.1 PFAM: CBS domain; Voltage gated chloride channel; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604310.1 PFAM: Transposase DDE domain; COGs: COG0628 permease; InterPro IPR002549; KEGG: ddf:DEFDS_2005 transporter; PFAM: Uncharacterised protein family UPF0118; SPTR: Transporter YP_004604311.1 PFAM: Domain of unknown function DUF20; COGs: COG0176 Transaldolase; HAMAP: transaldolase; InterPro IPR004731:IPR001585; KEGG: ddf:DEFDS_0352 transaldolase; PFAM: Transaldolase; SPTR: Probable transaldolase; TIGRFAM: Transaldolase C YP_004604312.1 PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family; InterPro IPR011017:IPR007029; KEGG: ddf:DEFDS_0351 hypothetical protein; PFAM: YHS; SMART: TRASH; SPTR: Putative uncharacterized protein YP_004604313.1 PFAM: YHS domain; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: ddf:DEFDS_0350 single-stranded nucleic acid binding protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Single-stranded nucleic acid binding protein YP_004604314.1 COGs: COG0706 Preprotein translocase subunit YidC; HAMAP: Membrane protein oxaA; InterPro IPR019998:IPR020001:IPR001708; KEGG: cni:Calni_1028 membrane protein insertase, YidC/oxa1 family; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Membrane protein oxaA; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; Membrane insertion protein, OxoA/YidC, N-terminal YP_004604315.1 PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain; COGs: COG0759 conserved hypothetical protein; HAMAP: Protein of unknown function DUF37; InterPro IPR002696; KEGG: ddf:DEFDS_0348 hypothetical protein; PFAM: Protein of unknown function DUF37; SPTR: UPF0161 protein DEFDS_0348; TIGRFAM: Protein of unknown function DUF37; manually curated YP_004604316.1 PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD; COGs: COG0594 RNase P protein component; HAMAP: Ribonuclease P; InterPro IPR000100; KEGG: ddf:DEFDS_0347 ribonuclease P protein component; PFAM: Ribonuclease P; SPTR: Ribonuclease P protein component; TIGRFAM: Ribonuclease P YP_004604317.1 PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial; HAMAP: 50S ribosomal protein L34; InterPro IPR000271; KEGG: dap:Dacet_0033 50S ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34 YP_004604318.1 PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type YP_004604319.1 PFAM: DNA methylase; InterPro IPR002789; KEGG: sea:SeAg_B4804 hypothetical protein; PFAM: Protein of unknown function DUF87; SPTR: Putative uncharacterized protein YP_004604320.1 PFAM: Domain of unknown function DUF87; InterPro IPR018977; KEGG: mma:MM_0197 hypothetical protein; PFAM: NurA domain; SPTR: Conserved protein YP_004604321.1 PFAM: NurA domain; manually curated YP_004604322.1 PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: pgn:PGN_0575 transposase in ISPg1; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604323.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR011777:IPR006076; KEGG: pca:Pcar_2388 flavoprotein-containing dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: Flavoprotein-containing dehydrogenase; TIGRFAM: Geranylgeranyl reductase, plant/prokaryotic YP_004604324.1 PFAM: FAD binding domain; TIGRFAM: geranylgeranyl reductase family; manually curated YP_004604325.1 PFAM: Transposase DDE domain; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: dap:Dacet_2797 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase YP_004604326.1 PFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0118 Glutamine amidotransferase; HAMAP: Imidazole glycerol phosphate synthase, subunit H; InterPro IPR010139:IPR000991; KEGG: cni:Calni_1940 imidazole glycerol phosphate synthase subunit HisH; PFAM: Glutamine amidotransferase class-I, C-terminal; SPTR: Imidazole glycerol phosphate synthase subunit hisH; TIGRFAM: Imidazole glycerol phosphate synthase, subunit H YP_004604327.1 PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; InterPro IPR006063:IPR006062; KEGG: cni:Calni_1939 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004604328.1 PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG1267 Phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: ddf:DEFDS_0041 phosphatidylglycerophosphatase; PFAM: Phosphatidylglycerophosphatase A; SPTR: Phosphatidylglycerophosphatase YP_004604329.1 PFAM: Phosphatidylglycerophosphatase A; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR008136:IPR001453; KEGG: cni:Calni_1937 competence/damage-inducible protein CinA; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal YP_004604330.1 PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1514 2'-5' RNA ligase; InterPro IPR004175:IPR014051; KEGG: ddf:DEFDS_0039 2'-5' RNA ligase; PFAM: Phosphoesterase, HXTX; SPTR: 2'-5' RNA ligase; TIGRFAM: 2',5' RNA ligase YP_004604331.1 PFAM: 2',5' RNA ligase family; TIGRFAM: 2'-5' RNA ligase; COGs: COG0468 RecA/RadA recombinase; HAMAP: DNA recombination and repair protein RecA; InterPro IPR013765:IPR003593; KEGG: ddf:DEFDS_0038 DNA recombination protein RecA; PFAM: DNA recombination and repair protein RecA; SMART: ATPase, AAA+ type, core; SPTR: Protein recA; TIGRFAM: DNA recombination and repair protein RecA YP_004604332.1 PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR001482; KEGG: ddf:DEFDS_0037 twitching motility protein PilT; PFAM: Type II secretion system protein E; SPTR: Twitching motility protein PilT; TIGRFAM: Pilus retraction protein PilT YP_004604333.1 PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT; COGs: COG2137 conserved hypothetical protein; KEGG: ddf:DEFDS_0036 regulatory protein RecX; SPTR: Regulatory protein recX YP_004604334.1 PFAM: RecX family; COGs: COG0359 Ribosomal protein L9; HAMAP: Ribosomal protein L9, bacteria/chloroplast; InterPro IPR020594:IPR020070:IPR020069; KEGG: bts:Btus_3301 ribosomal protein L9; PFAM: Ribosomal protein L9, C-terminal; Ribosomal protein L9, N-terminal; SPTR: 50S ribosomal protein L9; TIGRFAM: Ribosomal protein L9, bacteria/chloroplast YP_004604335.1 PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9; COGs: COG0305 Replicative DNA helicase; InterPro IPR007692:IPR003593:IPR007693:IPR007694; KEGG: ddf:DEFDS_0034 replicative DNA helicase DnaB; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Replicative DNA helicase DnaB; TIGRFAM: DNA helicase, DnaB type YP_004604336.1 PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; COGs: COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; HAMAP: UDP-3-O-acyl N-acetylglucosamine deacetylase; InterPro IPR004463; KEGG: ddf:DEFDS_0033 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; PFAM: UDP-3-O-acyl N-acetylglucosamine deacetylase; SPTR: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; TIGRFAM: UDP-3-O-acyl N-acetylglucosamine deacetylase YP_004604337.1 PFAM: UDP-3-O-acyl N-acetylglycosamine deacetylase; TIGRFAM: UDP-3-0-acyl N-acetylglucosamine deacetylase; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: ddf:DEFDS_1961 peptidase M48 family; PFAM: Peptidase M48, Ste24p; PRIAM: Ste24 endopeptidase; SPTR: Peptidase, M48 family YP_004604338.1 PFAM: Peptidase family M48; COGs: COG0442 Prolyl-tRNA synthetase; HAMAP: Prolyl-tRNA synthetase; InterPro IPR004500:IPR002314:IPR007214:IPR004154; KEGG: cni:Calni_0984 prolyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; YbaK/aminoacyl-tRNA synthetase associated region; Anticodon-binding; SPTR: Prolyl-tRNA synthetase; TIGRFAM: Prolyl-tRNA synthetase, class IIa, bacterial YP_004604339.1 PFAM: Anticodon binding domain; YbaK / prolyl-tRNA synthetases associated domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: ddf:DEFDS_1144 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein YP_004604340.1 PFAM: Radical SAM superfamily; COGs: COG0679 permease; InterPro IPR004776; KEGG: cni:Calni_0181 auxin efflux carrier; PFAM: Auxin efflux carrier; SPTR: Auxin Efflux Carrier YP_004604341.1 PFAM: Membrane transport protein; COGs: COG2255 Holliday junction resolvasome helicase subunit; HAMAP: DNA helicase, Holliday junction RuvB type; InterProIPR004605:IPR003593:IPR008824:IPR003959:IPR 008823; KEGG: ddf:DEFDS_1809 Holliday junction DNA helicase RuvB; PFAM: DNA helicase, Holliday junction RuvB type, C-terminal; ATPase, AAA-type, core; DNA helicase, Holliday junction RuvB type, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: DNA helicase, Holliday junction RuvB type YP_004604342.1 PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit; COGs: COG1066 ATP-dependent serine protease; InterPro IPR004504:IPR003593; KEGG: cni:Calni_0998 DNA replication and repair protein RadA; SMART: ATPase, AAA+ type, core; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA YP_004604343.1 PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA; COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: ddf:DEFDS_1807 enoyl-[acyl-carrier protein] reductase (NADH); PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: Enoyl-[acyl-carrier-protein] reductase [NADH] YP_004604344.1 PFAM: short chain dehydrogenase; InterPro IPR002482:IPR018392; KEGG: ddf:DEFDS_0274 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Putative uncharacterized protein YP_004604345.1 PFAM: LysM domain; COGs: COG1729 conserved hypothetical protein; InterPro IPR014162; KEGG: ddf:DEFDS_0275 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Tol-Pal system, YbgF YP_004604346.1 TIGRFAM: tol-pal system protein YbgF; COGs: COG1528 Ferritin-like protein; InterPro IPR008331; KEGG: ddf:DEFDS_0829 ferritin; PFAM: Ferritin/Dps protein; PRIAM: Ferroxidase; SPTR: Ferritin YP_004604347.1 PFAM: Ferritin-like domain; KEGG: cni:Calni_1683 hypothetical protein YP_004604348.1 COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR002541; KEGG: ddf:DEFDS_0177 heme exporter membrane protein; PFAM: Cytochrome c assembly protein; SPTR: Heme exporter membrane protein YP_004604349.1 PFAM: Cytochrome C assembly protein; COGs: COG2386 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR003544; KEGG: cni:Calni_1685 cytochrome c-type biogenesis protein CcmB; PFAM: Cytochrome c-type biogenesis protein CcmB; SPTR: Cytochrome c-type biogenesis protein CcmB YP_004604350.1 PFAM: CcmB protein; TIGRFAM: heme exporter protein CcmB; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ddf:DEFDS_0175 heme exporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Heme exporter ATP-binding protein YP_004604351.1 PFAM: ABC transporter; COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: ddf:DEFDS_0174 cytochrome c-type biogenesis protein CcmF; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c-type biogenesis protein CcmF YP_004604352.1 PFAM: Cytochrome C assembly protein; TIGRFAM: c-type cytochrome biogenesis protein CcmF; COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: cni:Calni_0661 peptidase M16 domain protein; PFAM: Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase M16 domain protein YP_004604353.1 PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); COGs: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); InterPro IPR002942; KEGG: dap:Dacet_0255 RNA-binding S4 domain protein; PFAM: RNA-binding S4; SMART: RNA-binding S4; SPTR: RNA-binding S4 domain protein YP_004604354.1 PFAM: S4 domain; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749; KEGG: cni:Calni_0108 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2 YP_004604355.1 PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR003141:IPR004013:IPR011708:IPR 004365; KEGG: ddf:DEFDS_2002 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit YP_004604356.1 PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc); COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: ddf:DEFDS_2001 molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region YP_004604357.1 PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB; COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: ddf:DEFDS_2000 hypothetical protein; PFAM: ComEC/Rec2-related protein; SPTR: Putative uncharacterized protein; TIGRFAM: ComEC/Rec2-related protein YP_004604358.1 PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR012729:IPR000594; KEGG: ddf:DEFDS_1999 thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: Thiamine biosynthesis protein ThiF; TIGRFAM: Thiamine biosynthesis protein ThiF YP_004604359.1 PFAM: ThiF family; TIGRFAM: thiamine biosynthesis protein ThiF, family 2; InterPro IPR010035:IPR003749; KEGG: dsa:Desal_2647 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis YP_004604360.1 PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_004604361.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610:IPR001667:IPR003156; KEGG: ddf:DEFDS_0047 single-strand DNA-specific exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Single-strand DNA-specific exonuclease; TIGRFAM: Bacterial RecJ exonuclease YP_004604362.1 PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR004811:IPR003607:IPR006674:IPR007685:IPR 004095:IPR002912; KEGG: ddf:DEFDS_0048 GTP pyrophosphokinase; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD region, subdomain; TGS; Amino acid-binding ACT; PRIAM: GTP diphosphokinase; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: GTP pyrophosphokinase; TIGRFAM: RelA/SpoT protein YP_004604363.1 PFAM: HD domain; ACT domain; Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family; COGs: COG0227 Ribosomal protein L28; HAMAP: Ribosomal protein L28; InterPro IPR001383; KEGG: ddf:DEFDS_0316 50S ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28 YP_004604364.1 PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; InterPro IPR015077; KEGG: ddf:DEFDS_0803 hypothetical protein; PFAM: Domain of unknown function DUF1858; SPTR: Putative uncharacterized protein YP_004604365.1 PFAM: Domain of unknown function (DUF1858); TIGRFAM: hydrid cluster protein-associated redox disulfide domain; COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; HAMAP: tRNA (guanine-N(7)-)-methyltransferase; InterPro IPR003358; KEGG: cni:Calni_0597 tRNA (guanine-n(7)-)-methyltransferase; PFAM: tRNA (guanine-N-7) methyltransferase; SPTR: tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N-7) methyltransferase YP_004604366.1 PFAM: Putative methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: dap:Dacet_0511 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative uncharacterized protein YP_004604367.1 PFAM: Clp protease; NfeD-like; KEGG: dap:Dacet_0510 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604368.1 PFAM: Protein of unknown function (DUF493); COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: ddf:DEFDS_0203 universal stress protein; PFAM: UspA; SPTR: Universal stress protein YP_004604369.1 PFAM: Universal stress protein family; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853:IPR010656; KEGG: dap:Dacet_1218 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein YP_004604370.1 PFAM: Domain of unknown function (DUF3394); DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: ddf:DEFDS_1847 TRAP-type transporter substrate-binding protein; SPTR: TRAP-type transport system, substrate-binding protein; TIGRFAM: TRAP transporter solute receptor, TAXI family YP_004604371.1 PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family; COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: UvrABC system protein C; InterPro IPR004791:IPR000305:IPR001943:IPR001162; KEGG: cni:Calni_1412 excinuclease abc, C subunit; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; UvrB/UvrC protein; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, C subunit YP_004604372.1 PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit; COGs: COG0797 Lipoprotein; InterPro IPR012997:IPR005132:IPR007730; KEGG: ddf:DEFDS_2081 rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation/cell division region, bacteria; SPTR: Rare lipoprotein A; TIGRFAM: Rare lipoprotein A, bacterial YP_004604373.1 PFAM: Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Sporulation related domain; TIGRFAM: rare lipoprotein A; COGs: COG2603 ATPase; InterPro IPR017582:IPR001763; KEGG: dap:Dacet_0054 tRNA 2-selenouridine synthase; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: tRNA 2-selenouridine synthase; TIGRFAM: tRNA 2-selenouridine synthase YP_004604374.1 PFAM: Rhodanese-like domain; TIGRFAM: tRNA 2-selenouridine synthase; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: cni:Calni_1696 transcriptional regulator, LysR family; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family YP_004604375.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; COGs: COG0260 Leucyl aminopeptidase; HAMAP: cytosol aminopeptidase; InterPro IPR000819; KEGG: ddf:DEFDS_2072 leucyl aminopeptidase; PFAM: Peptidase M17, leucyl aminopeptidase, C-terminal; SPTR: Probable cytosol aminopeptidase YP_004604376.1 PFAM: Cytosol aminopeptidase family, catalytic domain; Cytosol aminopeptidase family, N-terminal domain; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: tcx:Tcr_1009 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylglycohydrolase family protein YP_004604377.1 PFAM: ADP-ribosylglycohydrolase; KEGG: ddf:DEFDS_1792 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604378.1 COGs: COG2105 conserved hypothetical protein; InterPro IPR009288; KEGG: ddf:DEFDS_1791 hypothetical protein; PFAM: AIG2-like; SPTR: Putative uncharacterized protein YP_004604379.1 PFAM: AIG2-like family YP_004604380.1 COGs: COG5421 Transposase; KEGG: msv:Mesil_3173 transposase IS4 family protein; SPTR: Transposase IS4 family protein YP_004604381.1 PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: sun:SUN_2108 transposase; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 YP_004604382.1 PFAM: Transposase domain (DUF772) YP_004604383.1 PFAM: Response regulator receiver domain; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: dap:Dacet_2411 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein Dacet_2411; TIGRFAM: Uncharacterised protein family UPF0102 YP_004604384.1 PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: cni:Calni_1995 ribonuclease H; PFAM: Ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease YP_004604385.1 PFAM: Ribonuclease HII; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: cni:Calni_1996 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB YP_004604386.1 PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); HAMAP: Hydrogenase nickel incorporation protein HypA/HybF; InterPro IPR000688; KEGG: ddf:DEFDS_0183 hydrogenase expression/synthesis protein HypA; PFAM: Hydrogenase nickel incorporation protein HypA/HybF; SPTR: Probable hydrogenase nickel incorporation protein hypA; TIGRFAM: Hydrogenase nickel incorporation protein HypA/HybF YP_004604387.1 PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA; COGs: COG3605 Signal transduction protein containing GAF and PtsI domains; InterPro IPR003018:IPR008731:IPR008279:IPR000121; KEGG: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; GAF; PEP-utilising enzyme, mobile region; PRIAM: Phosphoenolpyruvate--protein phosphotransferase; SMART: GAF; SPTR: Phosphoenolpyruvate-protein phosphotransferase YP_004604388.1 PFAM: GAF domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR002489:IPR006076:IPR001327:IPR001450; KEGG: ddf:DEFDS_2136 ferredoxin-dependent glutamate synthase subunit beta; PFAM: FAD dependent oxidoreductase; Glutamate synthase, alpha subunit, C-terminal; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Glutamate synthase (NADPH); SPTR: Ferredoxin-dependent glutamate synthase, beta subunit YP_004604389.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; GXGXG motif; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR001450:IPR002932; KEGG: ddf:DEFDS_2137 ferredoxin-dependent glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Glutamate synthase (NADPH); SPTR: Ferredoxin-dependent glutamate synthase, alpha subunit YP_004604390.1 PFAM: 4Fe-4S binding domain; Conserved region in glutamate synthase; KEGG: ddf:DEFDS_2138 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604391.1 PFAM: Glutamine amidotransferases class-II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dap:Dacet_1550 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II YP_004604392.1 PFAM: Aminotransferase class I and II; COGs: COG0261 Ribosomal protein L21; HAMAP: Ribosomal protein L21; InterPro IPR001787; KEGG: ddf:DEFDS_0265 50S ribosomal protein L21; PFAM: Ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: Ribosomal protein L21 YP_004604393.1 PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21; COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: ddf:DEFDS_0266 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27 YP_004604394.1 PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; COGs: COG0536 GTPase; HAMAP: GTPase obg; InterPro IPR014100:IPR006169:IPR002917; KEGG: cni:Calni_2040 gtp-binding protein obg/CgtA; PFAM: GTP1/OBG subdomain; GTP-binding protein, HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA YP_004604395.1 PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; InterPro IPR007922; KEGG: ddf:DEFDS_0268 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein YP_004604396.1 PFAM: Protein of unknown function (DUF721); COGs: COG0242 N-formylmethionyl-tRNA deformylase; HAMAP: Formylmethionine deformylase; InterPro IPR000181; KEGG: dap:Dacet_0028 peptide deformylase; PFAM: Formylmethionine deformylase; SPTR: Peptide deformylase 1; TIGRFAM: Formylmethionine deformylase YP_004604397.1 PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase; COGs: COG2183 Transcriptional accessory protein; InterPro IPR018974:IPR003029:IPR006641; KEGG: dap:Dacet_1817 Tex-like protein protein-like protein; PFAM: Tex-like protein, N-terminal; Ribosomal protein S1, RNA binding domain; SMART: Resolvase, RNase H-like fold; SPTR: Tex-like protein protein-like protein YP_004604398.1 PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR011910:IPR002201; KEGG: ddf:DEFDS_1147 ADP-heptose:LPS heptosyltransferase II; PFAM: Glycosyl transferase, family 9; SPTR: ADP-heptose:LPS heptosyltransferase II; TIGRFAM: Lipopolysaccharide heptosyltransferase II YP_004604399.1 PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: ddf:DEFDS_1146 heptosyltransferase family protein; PFAM: Glycosyl transferase, family 9; SPTR: Heptosyltransferase family protein YP_004604400.1 PFAM: Glycosyltransferase family 9 (heptosyltransferase); COGs: COG1434 conserved hypothetical protein; InterPro IPR003848; KEGG: saf:SULAZ_1499 hypothetical protein; PFAM: Protein of unknown function DUF218; SPTR: Putative uncharacterized protein YP_004604401.1 PFAM: DUF218 domain; COGs: COG5421 Transposase; KEGG: msv:Mesil_3173 transposase IS4 family protein; SPTR: Transposase IS4 family protein YP_004604402.1 PFAM: Transposase DDE domain; manually curated YP_004604403.1 PFAM: Peptidase family M23; COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); HAMAP: Arginine biosynthesis protein ArgJ; InterPro IPR002813; KEGG: ddf:DEFDS_2004 arginine biosynthesis bifunctional protein ArgJ; PFAM: Arginine biosynthesis protein ArgJ; PRIAM: Glutamate N-acetyltransferase; SPTR: Arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: Arginine biosynthesis protein ArgJ YP_004604404.1 PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase; COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; HAMAP: N-acetyl-gamma-glutamyl-phosphate reductase; InterPro IPR000706:IPR000534:IPR012280; KEGG: ddf:DEFDS_0210 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, NAD-binding; Semialdehyde dehydrogenase, dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase YP_004604405.1 PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form; COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphatase; InterPro IPR008179; KEGG: cni:Calni_0265 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP pyrophosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase YP_004604406.1 PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0107 Imidazoleglycerol-phosphate synthase; HAMAP: Imidazole glycerol phosphate synthase subunit hisF; InterPro IPR004651:IPR006062; KEGG: dap:Dacet_3004 imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: Histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: Histidine biosynthesis, HisF YP_004604407.1 PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; COGs: COG2814 Arabinose efflux permease; InterPro IPR004638:IPR011701; KEGG: cni:Calni_1901 drug resistance transporter, EmrB/QacA subfamily; PFAM: Major facilitator superfamily MFS-1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily YP_004604408.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: ddf:DEFDS_0616 multidrug-efflux transporter MFP family; PFAM: Secretion protein HlyD; SPTR: Multidrug-efflux transporter, MFP family YP_004604409.1 PFAM: HlyD family secretion protein; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ddf:DEFDS_0615 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Putative uncharacterized protein YP_004604410.1 PFAM: Outer membrane efflux protein; COGs: COG1330 Exonuclease V gamma subunit; InterPro IPR006697; KEGG: gur:Gura_0582 exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit; PRIAM: Exodeoxyribonuclease V; SPTR: DNA helicase/exodeoxyribonuclease V, gamma subunit; TIGRFAM: Exodeoxyribonuclease V, RecC subunit YP_004604411.1 PFAM: Exodeoxyribonuclease V, gamma subunit; TIGRFAM: exodeoxyribonuclease V, gamma subunit; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR004586:IPR000212; KEGG: sat:SYN_02552 exodeoxyribonuclease V subunit beta; PFAM: DNA helicase, UvrD/REP type; SPTR: Putative uncharacterized protein; TIGRFAM: Exodeoxyribonuclease V, beta subunit YP_004604412.1 PFAM: UvrD/REP helicase; TIGRFAM: exodeoxyribonuclease V, beta subunit; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006344:IPR000606; KEGG: gem:GM21_0323 exodeoxyribonuclease V, alpha subunit; PFAM: RNA helicase 1, viral; PRIAM: Exodeoxyribonuclease V; SPTR: Exodeoxyribonuclease V, alpha subunit; TIGRFAM: Exodeoxyribonuclease V, alpha subunit YP_004604413.1 PFAM: Putative ATPase (DUF699); Viral (Superfamily 1) RNA helicase; TIGRFAM: exodeoxyribonuclease V, alpha subunit; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: dat:HRM2_35330 putative monovalent cation/H+ antiporter subunit D; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: MnhA1 YP_004604414.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; KEGG: dat:HRM2_35340 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604416.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750; KEGG: cni:Calni_0531 multisubunit sodium/proton antiporter, mrpd subunit; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Multisubunit sodium/proton antiporter, MrpD subunit YP_004604417.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: cni:Calni_0530 NADH/ubiquinone/plastoquinone (complex i); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH/Ubiquinone/plastoquinone (Complex I) YP_004604418.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: dal:Dalk_4921 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH:ubiquinone/quinone oxidoreductase, chain 4L; SPTR: NADH-ubiquinone oxidoreductase chain 4L YP_004604419.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; InterPro IPR007182; KEGG: cni:Calni_0528 na+/h+ antiporter MnhB subunit-related protein; PFAM: Na+/H+ antiporter MnhB subunit-related protein; SPTR: Na+/H+ antiporter MnhB subunit-related protein YP_004604420.1 PFAM: Domain related to MnhB subunit of Na+/H+ antiporter; KEGG: cni:Calni_0527 multicomponent na+-h+ antiporter subunit A; SPTR: Putative multicomponent Na+-H+ antiporter subunit A YP_004604421.1 COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: cni:Calni_0526 monovalent cation/proton antiporter, mnhg/PhaG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM: Na+/H+ antiporter subunit YP_004604422.1 PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; InterPro IPR007208; KEGG: cni:Calni_0525 multisubunit sodium/proton antiporter, mrpf subunit; PFAM: Multiple resistance and pH regulation protein F; SPTR: Multisubunit sodium/proton antiporter, MrpF subunit YP_004604423.1 PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF); COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: cni:Calni_0524 cation antiporter; PFAM: cation antiporter; SPTR: Cation antiporter YP_004604424.1 PFAM: Na+/H+ ion antiporter subunit; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR001453; KEGG: ddf:DEFDS_0823 molybdopterin biosynthesis protein; PFAM: Molybdopterin binding; SPTR: Molybdopterin biosynthesis protein YP_004604425.1 PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR005116:IPR003593; KEGG: ddf:DEFDS_0824 molybdate ABC transporter ATP-binding protein; PFAM: ABC transporter-like; Transport-associated OB, type 1; PRIAM: Molybdate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Molybdate ABC transporter, ATP-binding protein YP_004604426.1 PFAM: ABC transporter; TOBE domain; COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR005950:IPR006059; KEGG: ddf:DEFDS_0825 molybdate ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Molybdate ABC transporter, substrate-binding protein; TIGRFAM: Molybdenum ABC transporter, periplasmic binding protein YP_004604427.1 PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR000515; KEGG: ddf:DEFDS_0826 molybdate ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Molybdate ABC transporter, permease YP_004604428.1 PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817:IPR005110:IPR001453:IPR005111; KEGG: ddf:DEFDS_0827 molybdopterin biosynthesis protein MoeA; PFAM: Molybdopterin binding; MoeA, N-terminal region, domain I/II; MoeA, C-terminal, domain IV; SPTR: Molybdopterin biosynthesis protein MoeA; TIGRFAM: Molybdenum cofactor synthesis YP_004604429.1 PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0731 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: ddf:DEFDS_0828 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein YP_004604430.1 PFAM: Radical SAM superfamily; HAMAP: Ribosomal protein L25; InterPro IPR001021; KEGG: dap:Dacet_0468 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; SPTR: 50S ribosomal protein L25; TIGRFAM: Ribosomal protein L25 YP_004604431.1 PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form; KEGG: dap:Dacet_2467 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604432.1 This gene is disrupted by insertion of repetitive element; manually curated YP_004604433.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); InterPro IPR014865; KEGG: cni:Calni_0615 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604434.1 PFAM: DsrE/DsrF-like family; COGs: COG1794 Aspartate racemase; InterPro IPR004380:IPR015942; KEGG: swd:Swoo_1908 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Aspartate racemase; TIGRFAM: Aspartate racemase YP_004604435.1 PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: aspartate racemase; COGs: COG2606 conserved hypothetical protein; InterPro IPR004369:IPR007214; KEGG: glo:Glov_2948 YbaK/EbsC protein; PFAM: YbaK/aminoacyl-tRNA synthetase associated region; SPTR: YbaK/ebsC protein; TIGRFAM: Conserved hypothetical protein CHP00011 YP_004604436.1 PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein; COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: cni:Calni_0750 had-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1 YP_004604437.1 PFAM: haloacid dehalogenase-like hydrolase; manually curated YP_004604438.1 PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: drt:Dret_0685 amino acid carrier protein; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter YP_004604439.1 PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: ssm:Spirs_1245 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein YP_004604440.1 PFAM: Radical SAM superfamily; COGs: COG0171 NAD synthase; InterPro IPR003694; KEGG: kol:Kole_1677 NAD+ synthetase; PFAM: NAD+ synthase; PRIAM: NAD(+) synthase; SPTR: NH(3)-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthase YP_004604441.1 PFAM: NAD synthase; TIGRFAM: NAD+ synthetase; COGs: COG3621 Patatin; InterPro IPR002641; KEGG: mei:Msip34_1961 patatin; PFAM: Patatin; SPTR: Patatin YP_004604442.1 PFAM: Patatin-like phospholipase; COGs: COG3344 Retron-type reverse transcriptase; InterPro IPR000477:IPR013597; KEGG: nha:Nham_3886 RNA-directed DNA polymerase (reverse transcriptase); PFAM: RNA-directed DNA polymerase (reverse transcriptase); Group II intron, maturase-specific; SPTR: RNA-directed DNA polymerase (Reverse transcriptase) YP_004604443.1 PFAM: Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain; InterPro IPR003346; KEGG: sat:SYN_03159 transposase; PFAM: Transposase, IS116/IS110/IS902; SPTR: Transposase YP_004604444.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; KEGG: mfa:Mfla_1151 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604446.1 COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450; KEGG: dba:Dbac_2241 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004604447.1 COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006311:IPR006963:IPR006656:IPR006657; KEGG: dba:Dbac_2242 trimethylamine-N-oxide reductase (cytochrome c); PFAM: Molydopterin dinucleotide-binding region; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; PRIAM: Trimethylamine-N-oxide reductase (cytochrome c); SPTR: Trimethylamine-N-oxide reductase (Cytochrome c) YP_004604448.1 PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; COGs: COG3381 Uncharacterized component of anaerobic dehydrogenase; InterPro IPR010395; KEGG: drt:Dret_1230 cytoplasmic chaperone TorD family protein; SPTR: Cytoplasmic chaperone TorD family protein YP_004604449.1 PFAM: Nitrate reductase delta subunit; manually curated YP_004604450.1 PFAM: Integrase core domain; InterPro IPR002611; KEGG: toc:Toce_0299 IstB domain protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SPTR: IstB domain protein ATP-binding protein YP_004604451.1 PFAM: IstB-like ATP binding protein; InterPro IPR002559; KEGG: cni:Calni_2037 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604452.1 PFAM: Transposase DDE domain; manually curated YP_004604453.1 PFAM: Transposase DDE domain; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: msv:Mesil_3173 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604454.1 PFAM: Transposase DDE domain; KEGG: aeh:Mlg_0129 transposase, IS4 family protein; SPTR: Transposase YP_004604455.1 InterPro IPR005243; KEGG: dap:Dacet_2260 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2 YP_004604456.1 TIGRFAM: small redox-active disulfide protein 2; COGs: COG0701 permease; InterPro IPR005524; KEGG: cni:Calni_0175 permease; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: Permease YP_004604457.1 PFAM: Predicted permease; manually curated YP_004604458.1 PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin); COGs: COG2041 Sulfite oxidase; InterPro IPR000572; KEGG: ddf:DEFDS_0498 hypothetical protein; PFAM: Oxidoreductase, molybdopterin binding; SPTR: Putative uncharacterized protein YP_004604459.1 PFAM: Oxidoreductase molybdopterin binding domain; COGs: COG3153 acetyltransferase; InterPro IPR000182; KEGG: chl:Chy400_3399 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Probable acetyltransferase YP_004604460.1 PFAM: Acetyltransferase (GNAT) family; COGs: COG3467 flavin-nucleotide-binding protein; InterPro IPR011576; KEGG: geo:Geob_0985 pyridoxamine 5'-phosphate oxidase-related FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related FMN-binding YP_004604461.1 PFAM: Pyridoxamine 5'-phosphate oxidase; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839; KEGG: dap:Dacet_2893 transcriptional regulator, GntR family with aminotransferase domain; PFAM: HTH transcriptional regulator, GntR; Aminotransferase, class I/II; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family with aminotransferase domain YP_004604462.1 PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II; This gene is disrupted by insertion of repetitive element; manually curated YP_004604463.1 COGs: COG5421 Transposase; InterPro IPR002559; KEGG: msv:Mesil_3173 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein YP_004604464.1 PFAM: Transposase DDE domain; COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: rpc:RPC_4479 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: Short chain enoyl-CoA hydratase YP_004604465.1 PFAM: Enoyl-CoA hydratase/isomerase family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: pmo:Pmob_1584 GntR family transcriptional regulator; PFAM: Aminotransferase, class I/II; PRIAM: Aromatic-amino-acid transaminase; SPTR: Putative transcriptional regulator, GntR family YP_004604466.1 PFAM: Aminotransferase class I and II; COGs: COG2318 conserved hypothetical protein; InterPro IPR007837; KEGG: mmw:Mmwyl1_1368 DinB family protein; PFAM: DinB; SPTR: DinB family protein YP_004604467.1 PFAM: DinB family; InterPro IPR000620; KEGG: kse:Ksed_04860 membrane protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Integral membrane protein DUF6 YP_004604468.1 PFAM: EamA-like transporter family; COGs: COG2202 FOG: PAS/PAC domain; InterPro IPR000014:IPR013767:IPR013655:IPR001610; KEGG: dal:Dalk_3934 histidine kinase; PFAM: PAS fold; PAS fold-3; SMART: PAS; PAC motif; SPTR: Histidine kinase; TIGRFAM: PAS YP_004604469.1 PFAM: CHASE domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: pmx:PERMA_1548 sensor histidine kinase/response regulator; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; SPTR: ATP-binding region, ATPase-like:Histidine kinase A-like YP_004604470.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4968 Tfp pilus assembly protein PilE; InterPro IPR012902; KEGG: gme:Gmet_1399 N-terminal methylation; SPTR: N-terminal methylation YP_004604471.1 PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain YP_004604472.1 InterPro IPR007016; KEGG: emi:Emin_1087 O-antigen polymerase; PFAM: O-antigen ligase-related; SPTR: O-antigen polymerase YP_004604473.1 PFAM: O-Antigen ligase; InterPro IPR012902; KEGG: gme:Gmet_1399 N-terminal methylation; SPTR: N-terminal methylation YP_004604474.1 PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004604476.1 PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: ddf:DEFDS_1297 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604477.1 manually curated YP_004604478.1 COGs: COG4623 soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; InterPro IPR001638:IPR008258; KEGG: dol:Dole_2596 putative transglycosylase; PFAM: Extracellular solute-binding protein, family 3; Lytic transglycosylase-like, catalytic; SMART: Extracellular solute-binding protein, family 3; SPTR: Membrane-bound lytic murein transglycosylase F YP_004604479.1 PFAM: Transglycosylase SLT domain; Bacterial extracellular solute-binding proteins, family 3; COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR002525:IPR003346; KEGG: tye:THEYE_A0838 pilin inverting protein, putative; PFAM: Transposase, IS116/IS110/IS902; Transposase, IS111A/IS1328/IS1533; SPTR: Pilin inverting protein, putative YP_004604480.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase; COGs: COG0661 unusual protein kinase; InterPro IPR004147; KEGG: cni:Calni_1408 abc-1 domain-containing protein; PFAM: ABC-1; SPTR: ABC-1 domain-containing protein YP_004604481.1 PFAM: ABC1 family; COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR011108; KEGG: ddf:DEFDS_0408 hypothetical protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Putative uncharacterized protein YP_004604482.1 PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein; COGs: COG1968 Uncharacterized bacitracin resistance protein; HAMAP: Undecaprenyl-diphosphatase; InterPro IPR003824; KEGG: cni:Calni_1410 bacitracin resistance protein BacA; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenyl-diphosphatase YP_004604483.1 PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543:IPR018541:IPR003593; KEGG: dap:Dacet_2755 cell division FtsK/SpoIIIE; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase, AAA+ type, core; SPTR: Cell division FtsK/SpoIIIE YP_004604484.1 PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135; KEGG: cni:Calni_0761 dihydroorotate oxidase; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; SPTR: Dihydroorotate oxidase YP_004604485.1 PFAM: Dihydroorotate dehydrogenase; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050:IPR007197; KEGG: ddf:DEFDS_0011 hypothetical protein; PFAM: Radical SAM; SPTR: Putative uncharacterized protein; TIGRFAM: menaquinone biosynthesis protein; FO synthase, subunit 2 YP_004604486.1 PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family; COGs: COG0178 Excinuclease ATPase subunit; HAMAP: UvrABC system protein A; InterPro IPR004602:IPR003439; KEGG: ddf:DEFDS_0014 excinuclease ABC subunit A; PFAM: ABC transporter-like; SPTR: Excinuclease ABC, A subunit; TIGRFAM: Excinuclease ABC, A subunit YP_004604487.1 PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: ddf:DEFDS_0015 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase YP_004604488.1 PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; InterPro IPR007452; KEGG: cni:Calni_2065 hypothetical protein; PFAM: Protein of unknown function DUF490; SPTR: Putative uncharacterized protein YP_004604489.1 PFAM: Family of unknown function (DUF490); COGs: COG0729 Outer membrane protein; InterPro IPR010827:IPR000184; KEGG: cni:Calni_2066 surface antigen variable number repeat-containing protein; PFAM: Surface antigen variable number; Bacterial surface antigen (D15); SPTR: Surface antigen variable number repeat-containing protein YP_004604490.1 PFAM: Surface antigen variable number repeat; Surface antigen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479; KEGG: ddf:DEFDS_0018 peroxiredoxin; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin, C-terminal; PRIAM: Peroxiredoxin; SPTR: Peroxiredoxin YP_004604491.1 PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; KEGG: ddf:DEFDS_2073 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604492.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: ddf:DEFDS_2074 acetyl-CoA synthetase family protein; PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase family protein YP_004604493.1 PFAM: AMP-binding enzyme; COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: ddf:DEFDS_2076 enoyl-CoA hydratase/isomerase family protein; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase/isomerase family protein YP_004604494.1 PFAM: Enoyl-CoA hydratase/isomerase family; COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: dap:Dacet_2933 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase/isomerase YP_004604495.1 PFAM: Enoyl-CoA hydratase/isomerase family; COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794; KEGG: pmx:PERMA_0022 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase YP_004604496.1 PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; InterPro IPR006240:IPR000760; KEGG: nhl:Nhal_2283 3'(2'),5'-bisphosphate nucleotidase; PFAM: Inositol monophosphatase; SPTR: 3'(2'),5'-bisphosphate nucleotidase; TIGRFAM: 3(2),5 -bisphosphate nucleotidase, bacterial YP_004604497.1 PFAM: Inositol monophosphatase family; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase, bacterial; InterPro IPR002559; KEGG: pop:POPTR_597343 hypothetical protein; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family protein YP_004604498.1 PFAM: Transposase DDE domain; KEGG: ddf:DEFDS_0045 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604499.1 PFAM: Phosphate-starvation-inducible E; COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); HAMAP: Protein translocase subunit secA; InterProIPR000185:IPR011115:IPR011130:IPR001650:IPR 011116:IPR004027; KEGG: ddf:DEFDS_0046 preprotein translocase subunit A; PFAM: SecA DEAD-like; SecA preprotein cross-linking region; DNA/RNA helicase, C-terminal; SecA Wing/Scaffold; SEC-C motif; SMART: DNA/RNA helicase, C-terminal; SPTR: Protein translocase subunit secA; TIGRFAM: SecA protein YP_004604500.1 PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit; This gene is disrupted by insertion of repetitive element; manually curated YP_004604501.1 PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR004488:IPR002523; KEGG: pca:Pcar_2713 magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA-like; SPTR: Magnesium and cobalt transport protein CorA; TIGRFAM: Magnesium/cobalt transport protein CorA YP_004604502.1 PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA); manually curated YP_004604503.1 PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; HAMAP: UbiE/COQ5 methyltransferase; InterPro IPR004033; KEGG: ddf:DEFDS_1643 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; SPTR: Menaquinone biosynthesis methyltransferase ubiE; TIGRFAM: UbiE/COQ5 methyltransferase YP_004604504.1 PFAM: ubiE/COQ5 methyltransferase family; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; KEGG: ddf:DEFDS_1646 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604505.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR010237:IPR006402:IPR005834; KEGG: ddf:DEFDS_1650 pyrimidine 5'-nucleotidase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Pyrimidine 5'-nucleotidase; TIGRFAM: Pyrimidine 5-nucleotidase; HAD-superfamily hydrolase, subfamily IA, variant 3 YP_004604506.1 TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; pyrimidine 5'-nucleotidase; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: ddf:DEFDS_1906 histidine triad family protein; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad family protein YP_004604507.1 PFAM: HIT domain; COGs: COG0459 Chaperonin GroEL (HSP60 family); HAMAP: 60 kDa chaperonin; InterPro IPR001844:IPR002423; KEGG: ddf:DEFDS_0240 chaperonin GroEL; PFAM: Chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: Chaperonin Cpn60 YP_004604508.1 PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL; COGs: COG0234 Co-chaperonin GroES (HSP10); HAMAP: Chaperonin Cpn10, subgroup; InterPro IPR001476:IPR020818; KEGG: cni:Calni_2033 chaperonin cpn10; PFAM: Chaperonin Cpn10; SPTR: 10 kDa chaperonin YP_004604509.1 PFAM: Chaperonin 10 Kd subunit; COGs: COG0065 3-isopropylmalate dehydratase large subunit; HAMAP: 3-isopropylmalate dehydratase, large subunit region; InterPro IPR004430:IPR001030; KEGG: cni:Calni_2034 3-isopropylmalate dehydratase, large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: 3-isopropylmalate dehydratase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit region YP_004604510.1 PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR004431:IPR000573; KEGG: cni:Calni_2035 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: 3-isopropylmalate dehydratase small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit region YP_004604511.1 PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853:IPR010656; KEGG: cni:Calni_0389 trap transporter, 4tm/12tm fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein YP_004604512.1 PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: ddf:DEFDS_1400 TRAP-type transporter substrate-binding protein; SPTR: TRAP-type transport system, substrate-binding protein; TIGRFAM: TRAP transporter solute receptor, TAXI family YP_004604513.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; KEGG: ddf:DEFDS_1401 hypothetical protein; SPTR: Putative uncharacterized protein YP_004604514.1 PFAM: ABC transporter substrate binding protein; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: ddf:DEFDS_1402 two-component system, NtrC family, response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Two-component system, NtrC family, response regulator YP_004604515.1 PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003660:IPR003661:IPR003594; KEGG: ddf:DEFDS_1403 hypothetical protein; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Putative uncharacterized protein YP_004604516.1 PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: ddf:DEFDS_1547 solute:sodium symporter; PFAM: Sodium/solute symporter; SPTR: Solute:sodium symporter YP_004604517.1 PFAM: Sodium:solute symporter family; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR006424:IPR020828:IPR020829; KEGG: gbm:Gbem_3789 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I YP_004604518.1 PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0004 Ammonia permease; InterPro IPR019879:IPR001905; KEGG: hel:HELO_1099 ammonium transporter; PFAM: Ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: Probable ammonium transporter, marine subtype; Ammonium transporter YP_004604519.1 PFAM: Ammonium Transporter Family; TIGRFAM: probable ammonium transporter, marine subtype; ammonium transporter; COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: geo:Geob_1818 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SPTR: Nitrogen regulatory protein P-II YP_004604520.1 PFAM: Nitrogen regulatory protein P-II YP_004604521.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone protein dnaJ; InterPro IPR012724:IPR001623:IPR001305:IPR002939; KEGG: cni:Calni_0253 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich region; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ 2; TIGRFAM: Chaperone DnaJ YP_004604522.1 PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ; COGs: COG0443 Molecular chaperone; HAMAP: Chaperone DnaK; InterPro IPR012725:IPR013126; KEGG: ddf:DEFDS_2114 molecular chaperone DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: Chaperone DnaK YP_004604523.1 PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK; Fe-S protein assembly chaperone HscA; COGs: COG0576 Molecular chaperone GrpE (heat shock protein); HAMAP: GrpE nucleotide exchange factor; InterPro IPR000740; KEGG: ddf:DEFDS_2115 molecular chaperone GrpE; PFAM: GrpE nucleotide exchange factor; SPTR: Protein grpE YP_004604524.1 PFAM: GrpE; COGs: COG1420 Transcriptional regulator of heat shock gene; HAMAP: Negative regulator of class I heat shock protein; InterPro IPR002571; KEGG: cni:Calni_0250 heat-inducible transcription repressor HrcA; PFAM: Negative regulator of class I heat shock protein; SPTR: Heat-inducible transcription repressor hrcA; TIGRFAM: Negative regulator of class I heat shock protein YP_004604525.1 PFAM: HrcA protein C terminal domain; TIGRFAM: heat shock gene repressor HrcA; COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: ddf:DEFDS_2013 hypothetical protein; PFAM: Protein of unknown function DUF72; SPTR: Putative uncharacterized protein YP_004604526.1 PFAM: Protein of unknown function DUF72; KEGG: mfv:Mfer_0339 smc domain protein YP_004604527.1 Signal predicted by SignalP 3.0 HMM; IMG reference gene:2505696881_SP