-- dump date 20140619_091237 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 364106000001 SEQ_END SEQ_END NC_007941.1 114230 114230 DR NC_007941.1; contig end 114230..114230 Escherichia coli UTI89 364106000002 SEQ_END SEQ_END NC_007946.1 5065741 5065741 DR NC_007946.1; contig end 5065741..5065741 Escherichia coli UTI89 YP_538600.1 CDS UTI89_P001 NC_007941.1 1 591 D hypothetical protein 1..591 Escherichia coli UTI89 3996368 YP_538601.1 CDS repB NC_007941.1 831 1091 D replication protein 831..1091 Escherichia coli UTI89 3996369 YP_538602.1 CDS UTI89_P003 NC_007941.1 1324 1398 D RepA6; leader peptide RepL 1324..1398 Escherichia coli UTI89 3996370 YP_538603.1 CDS repA1 NC_007941.1 1391 2248 D RepA; replication protein 1391..2248 Escherichia coli UTI89 3996371 YP_538604.1 CDS UTI89_P005 NC_007941.1 3238 3831 R putative transposase complement(3238..3831) Escherichia coli UTI89 3996372 YP_538605.1 CDS UTI89_P006 NC_007941.1 3292 4008 D tnIS26; transposase for IS26 3292..4008 Escherichia coli UTI89 3996373 YP_538606.1 CDS scsC NC_007941.1 4056 4265 D secreted copper-sensitivity suppressor C 4056..4265 Escherichia coli UTI89 3996374 YP_538607.1 CDS scsD NC_007941.1 4255 4761 D secreted copper-sensitivity suppressor D 4255..4761 Escherichia coli UTI89 3996375 YP_538608.1 CDS UTI89_P009 NC_007941.1 4998 5759 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 4998..5759 Escherichia coli UTI89 3996376 YP_538609.1 CDS UTI89_P010 NC_007941.1 6106 7992 D hypothetical protein 6106..7992 Escherichia coli UTI89 3996377 YP_538610.1 CDS UTI89_P011 NC_007941.1 8033 8560 D hypothetical protein 8033..8560 Escherichia coli UTI89 3996378 YP_538611.1 CDS UTI89_P012 NC_007941.1 8664 10043 D hypothetical protein 8664..10043 Escherichia coli UTI89 3996379 YP_538612.1 CDS UTI89_P013 NC_007941.1 10046 11329 D hypothetical protein 10046..11329 Escherichia coli UTI89 3996380 YP_538613.1 CDS UTI89_P014 NC_007941.1 11319 12449 D putative integral membrane protein 11319..12449 Escherichia coli UTI89 3996381 YP_538614.1 CDS UTI89_P015 NC_007941.1 12454 13149 D ABC transporter, ATP-binding protein 12454..13149 Escherichia coli UTI89 3996382 YP_538615.1 CDS UTI89_P016 NC_007941.1 13136 13621 D putative thioredoxin-family protein 13136..13621 Escherichia coli UTI89 3996383 YP_538616.1 CDS UTI89_P017 NC_007941.1 13751 14131 D hypothetical protein 13751..14131 Escherichia coli UTI89 3996384 YP_538617.1 CDS UTI89_P018 NC_007941.1 15493 15918 D hypothetical protein 15493..15918 Escherichia coli UTI89 3996385 YP_538618.1 CDS UTI89_P019 NC_007941.1 15809 16204 D hypothetical protein 15809..16204 Escherichia coli UTI89 3996386 YP_538619.1 CDS UTI89_P020 NC_007941.1 16439 16855 D hypothetical protein 16439..16855 Escherichia coli UTI89 3996387 YP_538620.1 CDS UTI89_P021 NC_007941.1 16610 16936 R putative transposase OrfA protein of insertion sequence IS629 complement(16610..16936) Escherichia coli UTI89 3996388 YP_538621.1 CDS UTI89_P022 NC_007941.1 17038 17298 D hypothetical protein 17038..17298 Escherichia coli UTI89 3996389 YP_538622.1 CDS UTI89_P023 NC_007941.1 17295 17804 D hypothetical protein 17295..17804 Escherichia coli UTI89 3996390 YP_538623.1 CDS UTI89_P024 NC_007941.1 17824 18132 R hypothetical protein complement(17824..18132) Escherichia coli UTI89 3996391 YP_538624.1 CDS UTI89_P025 NC_007941.1 18200 18322 D hypothetical protein 18200..18322 Escherichia coli UTI89 3996392 YP_538625.1 CDS UTI89_P026 NC_007941.1 18300 18635 D immunity protein 18300..18635 Escherichia coli UTI89 3996393 YP_538626.1 CDS cjrA NC_007941.1 21105 21980 D putative inner membrane lipoprotein 21105..21980 Escherichia coli UTI89 3996394 YP_538627.1 CDS cjrB NC_007941.1 21988 22764 D putative periplasmic colicin Js sensitivity protein CjrB 21988..22764 Escherichia coli UTI89 3996395 YP_538628.1 CDS cjrC NC_007941.1 22933 25194 D putative outer membrane colicin Js receptor 22933..25194 Escherichia coli UTI89 3996396 YP_538629.1 CDS senB NC_007941.1 25164 26438 D enterotoxin TieB protein 25164..26438 Escherichia coli UTI89 3996397 YP_538630.1 CDS UTI89_P031 NC_007941.1 26961 27227 R transposase complement(26961..27227) Escherichia coli UTI89 3996398 YP_538631.1 CDS UTI89_P032 NC_007941.1 27292 27618 D hypothetical protein 27292..27618 Escherichia coli UTI89 3996399 YP_538632.1 CDS UTI89_P033 NC_007941.1 27760 28515 R insertion sequence ATP-binding protein complement(27760..28515) Escherichia coli UTI89 3996400 YP_538633.1 CDS UTI89_P034 NC_007941.1 28512 30011 R hypothetical protein complement(28512..30011) Escherichia coli UTI89 3996401 YP_538634.1 CDS UTI89_P035 NC_007941.1 30440 30811 R hypothetical protein complement(30440..30811) Escherichia coli UTI89 3996402 YP_538635.1 CDS UTI89_P036 NC_007941.1 30726 31151 R hypothetical protein complement(30726..31151) Escherichia coli UTI89 3996403 YP_538636.1 CDS UTI89_P037 NC_007941.1 31120 32628 D hypothetical protein 31120..32628 Escherichia coli UTI89 3996404 YP_538637.1 CDS UTI89_P038 NC_007941.1 33130 33534 D hypothetical protein 33130..33534 Escherichia coli UTI89 3996405 YP_538638.1 CDS UTI89_P039 NC_007941.1 33531 33878 D hypothetical protein 33531..33878 Escherichia coli UTI89 3996406 YP_538639.1 CDS UTI89_P040 NC_007941.1 34958 35980 D putative transposase 34958..35980 Escherichia coli UTI89 3996407 YP_538640.1 CDS UTI89_P041 NC_007941.1 35977 36759 D transposase/IS protein 35977..36759 Escherichia coli UTI89 3996408 YP_538641.1 CDS UTI89_P042 NC_007941.1 37498 38286 R hypothetical protein complement(37498..38286) Escherichia coli UTI89 3996409 YP_538642.1 CDS UTI89_P043 NC_007941.1 38296 40266 R putative hemin receptor complement(38296..40266) Escherichia coli UTI89 3996410 YP_538643.3 CDS UTI89_P044 NC_007941.1 40503 40913 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 40503..40913 Escherichia coli UTI89 3996411 YP_538644.1 CDS pixB NC_007941.1 41509 41781 D hypothetical protein 41509..41781 Escherichia coli UTI89 3996412 YP_538645.1 CDS UTI89_P046 NC_007941.1 44164 44352 D hypothetical serine-threonine protein kinase 44164..44352 Escherichia coli UTI89 3996413 YP_538646.1 CDS UTI89_P047 NC_007941.1 44334 44462 D hypothetical protein 44334..44462 Escherichia coli UTI89 3996414 YP_538647.1 CDS int NC_007941.1 44473 45213 D site-specific recombinase 44473..45213 Escherichia coli UTI89 3996415 YP_538648.1 CDS UTI89_P049 NC_007941.1 44902 45219 R hypothetical protein complement(44902..45219) Escherichia coli UTI89 3996416 YP_538649.1 CDS UTI89_P050 NC_007941.1 45456 46433 R replication protein RepFIB (P307 replicon) complement(45456..46433) Escherichia coli UTI89 3996417 YP_538650.1 CDS UTI89_P051 NC_007941.1 46171 46500 D hypothetical protein 46171..46500 Escherichia coli UTI89 3996418 YP_538651.1 CDS ydiA NC_007941.1 47608 48249 R hypothetical protein complement(47608..48249) Escherichia coli UTI89 3996419 YP_538652.1 CDS UTI89_P053 NC_007941.1 48236 48466 D hypothetical protein 48236..48466 Escherichia coli UTI89 3996420 YP_538653.1 CDS UTI89_P054 NC_007941.1 49212 49379 R hypothetical protein complement(49212..49379) Escherichia coli UTI89 3996421 YP_538654.1 CDS yeaA NC_007941.1 49706 49933 R hypothetical protein complement(49706..49933) Escherichia coli UTI89 3996422 YP_538655.1 CDS ccdA NC_007941.1 50571 50789 D plasmid maintenance protein CcdA 50571..50789 Escherichia coli UTI89 3996423 YP_538656.1 CDS ccdB NC_007941.1 50770 51096 D controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 50770..51096 Escherichia coli UTI89 3996424 YP_538657.1 CDS rsvB NC_007941.1 51097 51906 D resolvase 51097..51906 Escherichia coli UTI89 3996425 YP_538658.1 CDS UTI89_P059 NC_007941.1 51100 51780 R hypothetical protein complement(51100..51780) Escherichia coli UTI89 3996426 YP_538659.1 CDS UTI89_P060 NC_007941.1 52044 52319 R hypothetical protein complement(52044..52319) Escherichia coli UTI89 3996427 YP_538660.1 CDS UTI89_P061 NC_007941.1 52313 52957 R hypothetical protein complement(52313..52957) Escherichia coli UTI89 3996428 YP_538661.1 CDS stbA NC_007941.1 53186 54157 D stable plasmid inheritance protein 53186..54157 Escherichia coli UTI89 3996429 YP_538662.1 CDS stbB NC_007941.1 54162 54554 D stable plasmid inheritance protein 54162..54554 Escherichia coli UTI89 3996430 YP_538663.1 CDS impA NC_007941.1 55829 56266 R UV protection and mutation protein complement(55829..56266) Escherichia coli UTI89 3996431 YP_538664.1 CDS impC NC_007941.1 56263 56511 R UV protection and mutation protein complement(56263..56511) Escherichia coli UTI89 3996432 YP_538665.1 CDS UTI89_P066 NC_007941.1 56646 57164 D hypothetical protein 56646..57164 Escherichia coli UTI89 3996433 YP_538666.1 CDS UTI89_P067 NC_007941.1 57183 58403 D transposase 57183..58403 Escherichia coli UTI89 3996434 YP_538667.1 CDS UTI89_P068 NC_007941.1 58515 58784 D hypothetical protein 58515..58784 Escherichia coli UTI89 3996435 YP_538668.1 CDS yccB NC_007941.1 58798 59652 D hypothetical protein 58798..59652 Escherichia coli UTI89 3996436 YP_538669.1 CDS istB NC_007941.1 59646 60443 R IS21 putative ATP-binding protein complement(59646..60443) Escherichia coli UTI89 3996437 YP_538670.1 CDS istA NC_007941.1 60443 61615 R transposase for insertion sequence element IS21 complement(60443..61615) Escherichia coli UTI89 3996438 YP_538671.1 CDS UTI89_P072 NC_007941.1 61466 61687 D hypothetical protein 61466..61687 Escherichia coli UTI89 3996439 YP_538672.1 CDS UTI89_P073 NC_007941.1 61656 61859 D hypothetical protein 61656..61859 Escherichia coli UTI89 3996440 YP_538673.1 CDS yfbA NC_007941.1 61856 62167 D hypothetical protein 61856..62167 Escherichia coli UTI89 3996441 YP_538674.1 CDS UTI89_P075 NC_007941.1 62243 62926 D putative methylase 62243..62926 Escherichia coli UTI89 3996442 YP_538675.1 CDS yfeB NC_007941.1 62927 63148 D hypothetical protein 62927..63148 Escherichia coli UTI89 3996443 YP_538676.1 CDS yfcB NC_007941.1 63162 63596 D hypothetical protein 63162..63596 Escherichia coli UTI89 3996444 YP_538677.1 CDS ycfA NC_007941.1 63641 64411 D hypothetical protein 63641..64411 Escherichia coli UTI89 3996445 YP_538678.1 CDS yciB NC_007941.1 64827 65252 D hypothetical protein 64827..65252 Escherichia coli UTI89 3996446 YP_538679.1 CDS UTI89_P080 NC_007941.1 65299 65721 D hypothetical protein 65299..65721 Escherichia coli UTI89 3996447 YP_538680.1 CDS UTI89_P081 NC_007941.1 65718 65909 D hypothetical protein 65718..65909 Escherichia coli UTI89 3996448 YP_538681.1 CDS ycjB NC_007941.1 65773 66156 D hypothetical protein 65773..66156 Escherichia coli UTI89 3996449 YP_538682.1 CDS UTI89_P083 NC_007941.1 65886 66380 R hypothetical protein complement(65886..66380) Escherichia coli UTI89 3996450 YP_538683.1 CDS UTI89_P084 NC_007941.1 66029 66388 D hypothetical protein 66029..66388 Escherichia coli UTI89 3996451 YP_538684.1 CDS UTI89_P085 NC_007941.1 66356 66613 R hypothetical protein complement(66356..66613) Escherichia coli UTI89 3996452 YP_538685.1 CDS UTI89_P086 NC_007941.1 66872 67102 D hypothetical protein 66872..67102 Escherichia coli UTI89 3996453 YP_538686.1 CDS UTI89_P087 NC_007941.1 66890 67150 R hypothetical protein complement(66890..67150) Escherichia coli UTI89 3996454 YP_538687.1 CDS ydbA NC_007941.1 67154 68515 D hypothetical protein 67154..68515 Escherichia coli UTI89 3996455 YP_538688.1 CDS UTI89_P089 NC_007941.1 68562 69125 D hypothetical protein 68562..69125 Escherichia coli UTI89 3996456 YP_538689.1 CDS UTI89_P090 NC_007941.1 69211 69669 R hypothetical protein complement(69211..69669) Escherichia coli UTI89 3996457 YP_538690.1 CDS UTI89_P091 NC_007941.1 69670 69906 R hypothetical protein complement(69670..69906) Escherichia coli UTI89 3996458 YP_538691.1 CDS ssb NC_007941.1 69932 70498 D single-stranded DNA-binding protein 69932..70498 Escherichia coli UTI89 3996459 YP_538692.1 CDS ydeA NC_007941.1 70549 70788 D hypothetical protein 70549..70788 Escherichia coli UTI89 3996460 YP_538693.3 CDS ycjA NC_007941.1 70757 72805 D hypothetical protein 70757..72805 Escherichia coli UTI89 3996461 YP_538694.1 CDS psiB NC_007941.1 72860 73294 D plasmid SOS inhibition protein B 72860..73294 Escherichia coli UTI89 3996462 YP_538695.1 CDS UTI89_P096 NC_007941.1 73291 74010 D PsiA; plasmid SOS inhibition protein A 73291..74010 Escherichia coli UTI89 3996463 YP_538696.1 CDS UTI89_P097 NC_007941.1 74228 74440 D Mok; similar to F leading maintenance protein C; modulator of post-segregation killing protein 74228..74440 Escherichia coli UTI89 3996464 YP_538697.1 CDS flmA NC_007941.1 74286 74444 D small toxic polypeptide 74286..74444 Escherichia coli UTI89 3996465 YP_538698.1 CDS UTI89_P099 NC_007941.1 75060 75296 R hypothetical protein complement(75060..75296) Escherichia coli UTI89 3996466 YP_538699.1 CDS UTI89_P100 NC_007941.1 75360 75647 D hypothetical protein 75360..75647 Escherichia coli UTI89 3996467 YP_538700.1 CDS UTI89_P101 NC_007941.1 75766 76587 D hypothetical protein 75766..76587 Escherichia coli UTI89 3996468 YP_538701.1 CDS UTI89_P102 NC_007941.1 76883 77392 R lytic transglycosylase complement(76883..77392) Escherichia coli UTI89 3996469 YP_538702.1 CDS traM NC_007941.1 77816 78199 D conjugal transfer protein TraM 77816..78199 Escherichia coli UTI89 3996470 YP_538703.1 CDS traJ NC_007941.1 78333 79079 D functional relaxosome complex initiator 78333..79079 Escherichia coli UTI89 3996471 YP_538704.1 CDS traY NC_007941.1 79173 79400 D conjugal transfer protein TraY 79173..79400 Escherichia coli UTI89 3996472 YP_538705.1 CDS traA NC_007941.1 79434 79793 D conjugal transfer pilin subunit TraA 79434..79793 Escherichia coli UTI89 3996473 YP_538706.1 CDS traL NC_007941.1 79808 80119 D conjugal transfer pilus assembly protein TraL 79808..80119 Escherichia coli UTI89 3996474 YP_538707.1 CDS traE NC_007941.1 80141 80707 D conjugal transfer pilus assembly protein TraE 80141..80707 Escherichia coli UTI89 3996475 YP_538708.1 CDS traK NC_007941.1 80694 81422 D conjugal transfer protein TraK 80694..81422 Escherichia coli UTI89 3996476 YP_538709.1 CDS traB NC_007941.1 81422 82849 D conjugal transfer pilus assembly protein TraB 81422..82849 Escherichia coli UTI89 3996477 YP_538710.1 CDS traP NC_007941.1 82839 83429 D conjugal transfer protein TraP 82839..83429 Escherichia coli UTI89 3996478 YP_538711.1 CDS trbD NC_007941.1 83368 83736 D conjugal transfer protein TrbD 83368..83736 Escherichia coli UTI89 3996479 YP_538712.1 CDS traV NC_007941.1 83978 84493 D conjugal transfer protein TraV 83978..84493 Escherichia coli UTI89 3996480 YP_538713.1 CDS traR NC_007941.1 84628 84849 D conjugal transfer protein TraR 84628..84849 Escherichia coli UTI89 3996481 YP_538714.1 CDS yfiA NC_007941.1 84842 85315 D hypothetical protein 84842..85315 Escherichia coli UTI89 3996482 YP_538715.1 CDS UTI89_P116 NC_007941.1 85395 85613 D hypothetical protein 85395..85613 Escherichia coli UTI89 3996483 YP_538716.1 CDS traC NC_007941.1 85980 88610 D similar to VirB4; conjugal transfer ATP-binding protein TraC 85980..88610 Escherichia coli UTI89 3996484 YP_538717.1 CDS trbI NC_007941.1 88607 88993 D conjugal transfer protein TrbI 88607..88993 Escherichia coli UTI89 3996485 YP_538718.1 CDS traW NC_007941.1 88990 89622 D conjugal transfer pilus assembly protein TraW 88990..89622 Escherichia coli UTI89 3996486 YP_538719.1 CDS traU NC_007941.1 89619 90611 D conjugal transfer pilus assembly protein TraU 89619..90611 Escherichia coli UTI89 3996487 YP_538720.1 CDS UTI89_P121 NC_007941.1 90635 90946 D hypothetical protein 90635..90946 Escherichia coli UTI89 3996488 YP_538721.1 CDS trbC NC_007941.1 90955 91593 D conjugal transfer pilus assembly protein TrbC 90955..91593 Escherichia coli UTI89 3996489 YP_538722.1 CDS traN NC_007941.1 91590 93440 D TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 91590..93440 Escherichia coli UTI89 3996490 YP_538723.1 CDS trbE NC_007941.1 93464 93724 D conjugal transfer protein TrbE 93464..93724 Escherichia coli UTI89 3996491 YP_538724.1 CDS traF NC_007941.1 93687 94460 D type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal pilus assembly protein TraF 93687..94460 Escherichia coli UTI89 3996492 YP_538725.1 CDS trbA NC_007941.1 94474 94815 D conjugal transfer protein TrbA 94474..94815 Escherichia coli UTI89 3996493 YP_538726.1 CDS artA NC_007941.1 94796 95131 R hypothetical protein complement(94796..95131) Escherichia coli UTI89 3996494 YP_538727.1 CDS traQ NC_007941.1 95212 95496 D conjugal transfer pilin chaperone TraQ 95212..95496 Escherichia coli UTI89 3996495 YP_538728.1 CDS trbB NC_007941.1 95483 96028 D conjugal transfer protein TrbB 95483..96028 Escherichia coli UTI89 3996496 YP_538729.1 CDS trbJ NC_007941.1 95958 96305 D conjugal transfer protein TrbJ 95958..96305 Escherichia coli UTI89 3996497 YP_538730.1 CDS trbF NC_007941.1 96253 96678 D conjugal transfer protein TrbF 96253..96678 Escherichia coli UTI89 3996498 YP_538731.1 CDS traH NC_007941.1 96656 98038 D conjugal transfer pilus assembly protein TraH 96656..98038 Escherichia coli UTI89 3996499 YP_538732.1 CDS traG NC_007941.1 98035 100857 D conjugal transfer mating pair stabilization protein TraG 98035..100857 Escherichia coli UTI89 3996500 YP_538733.1 CDS traS NC_007941.1 100873 101358 D surface exclusion inner membrane protein 100873..101358 Escherichia coli UTI89 3996501 YP_538734.1 CDS traT NC_007941.1 101407 102138 D conjugal transfer surface exclusion protein TraT 101407..102138 Escherichia coli UTI89 3996502 YP_538735.1 CDS yhfA NC_007941.1 102296 103078 D hypothetical protein 102296..103078 Escherichia coli UTI89 3996503 YP_538736.1 CDS traD NC_007941.1 103129 105273 D type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD 103129..105273 Escherichia coli UTI89 3996504 YP_538737.1 CDS traI NC_007941.1 105273 110543 D cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer nickase/helicase TraI 105273..110543 Escherichia coli UTI89 3996505 YP_538738.1 CDS UTI89_P139 NC_007941.1 107306 107875 R hypothetical protein complement(107306..107875) Escherichia coli UTI89 3996506 YP_538739.1 CDS traX NC_007941.1 110506 111309 D conjugal transfer pilus acetylation protein TraX 110506..111309 Escherichia coli UTI89 3996507 YP_538740.1 CDS UTI89_P141 NC_007941.1 111368 112228 D hypothetical protein 111368..112228 Escherichia coli UTI89 3996508 YP_538741.1 CDS finO NC_007941.1 112331 112891 D conjugal transfer fertility inhibition protein FinO 112331..112891 Escherichia coli UTI89 3996509 YP_538742.1 CDS UTI89_P143 NC_007941.1 113020 113232 D hypothetical protein 113020..113232 Escherichia coli UTI89 3996510 YP_538743.1 CDS UTI89_P144 NC_007941.1 113465 113938 D hypothetical protein 113465..113938 Escherichia coli UTI89 3996511 YP_538744.1 CDS hmo NC_007941.1 113984 114193 D putative regulator 113984..114193 Escherichia coli UTI89 3996512 YP_539042.1 CDS thrL NC_007946.1 190 255 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 190..255 Escherichia coli UTI89 3993026 YP_539043.1 CDS thrA NC_007946.1 336 2798 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 336..2798 Escherichia coli UTI89 3993027 YP_539044.1 CDS thrB NC_007946.1 2800 3732 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2800..3732 Escherichia coli UTI89 3993028 YP_539045.1 CDS thrC NC_007946.1 3733 5019 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3733..5019 Escherichia coli UTI89 3993029 YP_539046.1 CDS yaaX NC_007946.1 5233 5529 D hypothetical protein 5233..5529 Escherichia coli UTI89 3993030 YP_539047.1 CDS UTI89_C0006 NC_007946.1 5309 5557 R hypothetical protein complement(5309..5557) Escherichia coli UTI89 3993031 YP_539048.1 CDS yaaA NC_007946.1 5569 6345 R hypothetical protein complement(5569..6345) Escherichia coli UTI89 3993032 YP_539049.1 CDS yaaJ NC_007946.1 6415 7845 R transporter YaaJ complement(6415..7845) Escherichia coli UTI89 3993033 YP_539050.2 CDS talB NC_007946.1 8124 9077 D transaldolase B 8124..9077 Escherichia coli UTI89 3993034 YP_539051.1 CDS mogA NC_007946.1 9189 9779 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9189..9779 Escherichia coli UTI89 3993035 YP_539052.1 CDS yaaH NC_007946.1 9984 10550 R hypothetical protein complement(9984..10550) Escherichia coli UTI89 3993036 YP_539053.1 CDS yaaW NC_007946.1 10699 11412 R hypothetical protein complement(10699..11412) Escherichia coli UTI89 3993037 YP_539055.1 CDS yaaI NC_007946.1 11438 11842 R hypothetical protein complement(11438..11842) Escherichia coli UTI89 3993039 YP_539056.1 CDS UTI89_C0015 NC_007946.1 12172 14208 R glutamate dehydrogenase complement(12172..14208) Escherichia coli UTI89 3993040 YP_539057.1 CDS dnaK NC_007946.1 12214 14130 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12214..14130 Escherichia coli UTI89 3993041 YP_539058.1 CDS dnaJ NC_007946.1 14219 15349 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 14219..15349 Escherichia coli UTI89 3993042 YP_539059.1 CDS gef NC_007946.1 15454 15663 R gef membrane toxin complement(15454..15663) Escherichia coli UTI89 3993043 YP_539060.1 CDS UTI89_C0019 NC_007946.1 16218 16979 D hypothetical protein 16218..16979 Escherichia coli UTI89 3992736 YP_539061.1 CDS UTI89_C0020 NC_007946.1 16963 18492 D hypothetical protein 16963..18492 Escherichia coli UTI89 3992737 YP_539062.1 CDS UTI89_C0021 NC_007946.1 18621 19880 D hypothetical protein 18621..19880 Escherichia coli UTI89 3992738 YP_539063.1 CDS nhaA NC_007946.1 20115 21281 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 20115..21281 Escherichia coli UTI89 3992739 YP_539064.2 CDS nhaR NC_007946.1 21347 22246 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 21347..22246 Escherichia coli UTI89 3992740 YP_539065.1 CDS UTI89_C0024 NC_007946.1 22258 22590 D hypothetical protein 22258..22590 Escherichia coli UTI89 3992741 YP_539066.1 CDS rpsT NC_007946.1 22342 22605 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(22342..22605) Escherichia coli UTI89 3992742 YP_539067.1 CDS yaaY NC_007946.1 22708 22926 D hypothetical protein 22708..22926 Escherichia coli UTI89 3992743 YP_539068.1 CDS ribF NC_007946.1 22934 23875 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 22934..23875 Escherichia coli UTI89 3992744 YP_539069.1 CDS ileS NC_007946.1 23918 26734 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 23918..26734 Escherichia coli UTI89 3992745 YP_539070.1 CDS lspA NC_007946.1 26734 27228 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 26734..27228 Escherichia coli UTI89 3992746 YP_539071.1 CDS slpA NC_007946.1 27336 27785 D peptidyl-prolyl cis- trans isomerase 27336..27785 Escherichia coli UTI89 3992747 YP_539072.1 CDS ispH NC_007946.1 27787 28737 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 27787..28737 Escherichia coli UTI89 3992748 YP_539073.1 CDS yaaF NC_007946.1 28803 29717 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 28803..29717 Escherichia coli UTI89 3992749 YP_539074.1 CDS UTI89_C0033 NC_007946.1 29740 30105 D hypothetical protein 29740..30105 Escherichia coli UTI89 3992750 YP_539075.1 CDS dapB NC_007946.1 30266 31087 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 30266..31087 Escherichia coli UTI89 3992751 YP_539076.1 CDS UTI89_C0035 NC_007946.1 31099 31296 R hypothetical protein complement(31099..31296) Escherichia coli UTI89 3992752 YP_539077.1 CDS carA NC_007946.1 31516 32691 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 31516..32691 Escherichia coli UTI89 3992753 YP_539078.1 CDS carB NC_007946.1 32709 35930 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 32709..35930 Escherichia coli UTI89 3992754 YP_539079.1 CDS UTI89_C0038 NC_007946.1 36103 36612 D transposase 36103..36612 Escherichia coli UTI89 3992755 YP_539080.1 CDS UTI89_C0039 NC_007946.1 36649 36867 R hypothetical protein complement(36649..36867) Escherichia coli UTI89 3993409 YP_539081.2 CDS caiF NC_007946.1 36902 37297 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 36902..37297 Escherichia coli UTI89 3993410 YP_539082.1 CDS caiE NC_007946.1 37416 38027 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(37416..38027) Escherichia coli UTI89 3993411 YP_539083.1 CDS caiD NC_007946.1 38012 38905 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(38012..38905) Escherichia coli UTI89 3993412 YP_539084.1 CDS caiC NC_007946.1 38906 40474 R crotonobetaine/carnitine-CoA ligase complement(38906..40474) Escherichia coli UTI89 3993413 YP_539085.1 CDS caiB NC_007946.1 40532 41749 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(40532..41749) Escherichia coli UTI89 3993414 YP_539086.1 CDS caiA NC_007946.1 41877 43019 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(41877..43019) Escherichia coli UTI89 3993415 YP_539087.1 CDS caiT NC_007946.1 43050 44564 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(43050..44564) Escherichia coli UTI89 3993416 YP_539088.2 CDS fixA NC_007946.1 45037 45807 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45037..45807 Escherichia coli UTI89 3993417 YP_539089.1 CDS fixB NC_007946.1 45822 46763 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 45822..46763 Escherichia coli UTI89 3993418 YP_539090.1 CDS fixC NC_007946.1 46814 48100 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 46814..48100 Escherichia coli UTI89 3993419 YP_539091.1 CDS fixX NC_007946.1 48097 48384 D ferredoxin 48097..48384 Escherichia coli UTI89 3993420 YP_539092.1 CDS yaaU NC_007946.1 48443 49774 D metabolite transport protein YaaU 48443..49774 Escherichia coli UTI89 3993421 YP_539093.1 CDS yabF NC_007946.1 49882 50412 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 49882..50412 Escherichia coli UTI89 3993422 YP_539094.1 CDS kefC NC_007946.1 50405 52267 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 50405..52267 Escherichia coli UTI89 3993423 YP_539095.1 CDS folA NC_007946.1 52324 52938 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52324..52938 Escherichia coli UTI89 3993424 YP_539096.1 CDS UTI89_C0055 NC_007946.1 53024 53257 D antitoxin of gyrase inhibiting toxin-antitoxin system 53024..53257 Escherichia coli UTI89 3993425 YP_539097.1 CDS apaH NC_007946.1 53572 54420 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(53572..54420) Escherichia coli UTI89 3993426 YP_539098.1 CDS apaG NC_007946.1 54427 54804 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(54427..54804) Escherichia coli UTI89 3993427 YP_539099.1 CDS ksgA NC_007946.1 54807 55628 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(54807..55628) Escherichia coli UTI89 3993619 YP_539100.1 CDS pdxA NC_007946.1 55625 56614 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(55625..56614) Escherichia coli UTI89 3993620 YP_539101.1 CDS surA NC_007946.1 56614 57900 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(56614..57900) Escherichia coli UTI89 3993621 YP_539102.1 CDS imp NC_007946.1 57953 60307 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(57953..60307) Escherichia coli UTI89 3993622 YP_539103.2 CDS djlA NC_007946.1 60562 61377 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 60562..61377 Escherichia coli UTI89 3993623 YP_539104.1 CDS rluA NC_007946.1 61527 62186 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(61527..62186) Escherichia coli UTI89 3993624 YP_539105.1 CDS hepA NC_007946.1 62198 65104 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(62198..65104) Escherichia coli UTI89 3993625 YP_539106.1 CDS polB NC_007946.1 65268 67619 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(65268..67619) Escherichia coli UTI89 3993626 YP_539107.1 CDS araD NC_007946.1 67694 68389 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(67694..68389) Escherichia coli UTI89 3993627 YP_539108.1 CDS araA NC_007946.1 68674 70176 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(68674..70176) Escherichia coli UTI89 3993628 YP_539109.1 CDS araB NC_007946.1 70187 71887 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(70187..71887) Escherichia coli UTI89 3993629 YP_539110.1 CDS araC NC_007946.1 72175 73071 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 72175..73071 Escherichia coli UTI89 3993630 YP_539111.1 CDS UTI89_C0070 NC_007946.1 73336 73458 D hypothetical protein 73336..73458 Escherichia coli UTI89 3993631 YP_539112.1 CDS UTI89_C0071 NC_007946.1 73583 74194 D hypothetical protein 73583..74194 Escherichia coli UTI89 3993632 YP_539113.1 CDS UTI89_C0072 NC_007946.1 74440 74862 D hypothetical protein 74440..74862 Escherichia coli UTI89 3993633 YP_539114.1 CDS yabI NC_007946.1 75017 75781 D hypothetical protein 75017..75781 Escherichia coli UTI89 3993634 YP_539115.1 CDS thiQ NC_007946.1 75895 76614 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(75895..76614) Escherichia coli UTI89 3993635 YP_539116.1 CDS thiP NC_007946.1 76577 78187 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(76577..78187) Escherichia coli UTI89 3993636 YP_539117.2 CDS tbpA NC_007946.1 78163 79146 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(78163..79146) Escherichia coli UTI89 3993637 YP_539118.1 CDS yabN NC_007946.1 79310 80986 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(79310..80986) Escherichia coli UTI89 3993638 YP_539119.1 CDS leuD NC_007946.1 81293 81898 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(81293..81898) Escherichia coli UTI89 3994500 YP_539120.1 CDS leuC NC_007946.1 81909 83309 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(81909..83309) Escherichia coli UTI89 3994501 YP_539121.1 CDS leuB NC_007946.1 83312 84406 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(83312..84406) Escherichia coli UTI89 3994502 YP_539122.1 CDS leuA NC_007946.1 84403 85974 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(84403..85974) Escherichia coli UTI89 3994503 YP_539123.1 CDS leuL NC_007946.1 86066 86152 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(86066..86152) Escherichia coli UTI89 3994504 YP_539124.1 CDS UTI89_C0083 NC_007946.1 86611 86733 D hypothetical protein 86611..86733 Escherichia coli UTI89 3994505 YP_539125.1 CDS leuO NC_007946.1 86810 87754 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 86810..87754 Escherichia coli UTI89 3994506 YP_539126.2 CDS ilvI NC_007946.1 88072 89796 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 88072..89796 Escherichia coli UTI89 3994507 YP_539127.2 CDS ilvH NC_007946.1 89799 90290 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 89799..90290 Escherichia coli UTI89 3994508 YP_539128.1 CDS fruL NC_007946.1 90293 90388 D FruR leader peptide 90293..90388 Escherichia coli UTI89 3994509 YP_539129.1 CDS UTI89_C0088 NC_007946.1 90342 90473 D hypothetical protein 90342..90473 Escherichia coli UTI89 3994510 YP_539130.1 CDS fruR NC_007946.1 90470 91474 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 90470..91474 Escherichia coli UTI89 3994511 YP_539131.1 CDS mraZ NC_007946.1 92040 92534 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 92040..92534 Escherichia coli UTI89 3994512 YP_539132.1 CDS mraW NC_007946.1 92536 93477 D yabC, orfB; S-adenosyl-methyltransferase 92536..93477 Escherichia coli UTI89 3994513 YP_539133.1 CDS ftsL NC_007946.1 93474 93839 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 93474..93839 Escherichia coli UTI89 3994514 YP_539134.1 CDS ftsI NC_007946.1 93855 95621 D peptidoglycan synthetase FtsI 93855..95621 Escherichia coli UTI89 3994515 YP_539135.1 CDS murE NC_007946.1 95608 97095 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 95608..97095 Escherichia coli UTI89 3994516 YP_539136.1 CDS murF NC_007946.1 97092 98450 D UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 97092..98450 Escherichia coli UTI89 3994517 YP_539137.1 CDS mraY NC_007946.1 98444 99526 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 98444..99526 Escherichia coli UTI89 3994518 YP_539138.1 CDS murD NC_007946.1 99529 100845 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 99529..100845 Escherichia coli UTI89 3992618 YP_539139.1 CDS ftsW NC_007946.1 100842 102089 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 100842..102089 Escherichia coli UTI89 3992619 YP_539140.1 CDS murG NC_007946.1 102086 103153 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 102086..103153 Escherichia coli UTI89 3992620 YP_539141.1 CDS murC NC_007946.1 103207 104682 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 103207..104682 Escherichia coli UTI89 3992621 YP_539142.1 CDS ddl NC_007946.1 104675 105595 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 104675..105595 Escherichia coli UTI89 3992622 YP_539143.1 CDS ftsQ NC_007946.1 105597 106427 D involved in septum formation; cell division protein FtsQ 105597..106427 Escherichia coli UTI89 3992623 YP_539144.1 CDS ftsA NC_007946.1 106424 107686 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 106424..107686 Escherichia coli UTI89 3992624 YP_539145.1 CDS ftsZ NC_007946.1 107747 108898 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 107747..108898 Escherichia coli UTI89 3992625 YP_539146.1 CDS lpxC NC_007946.1 108999 109916 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 108999..109916 Escherichia coli UTI89 3992626 YP_539147.2 CDS secM NC_007946.1 110147 110659 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 110147..110659 Escherichia coli UTI89 3992627 YP_539148.1 CDS secA NC_007946.1 110721 113426 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 110721..113426 Escherichia coli UTI89 3992628 YP_539149.1 CDS mutT NC_007946.1 113486 113884 D nucleoside triphosphate pyrophosphohydrolase 113486..113884 Escherichia coli UTI89 3992629 YP_539150.1 CDS yacG NC_007946.1 113972 114169 R zinc-binding protein complement(113972..114169) Escherichia coli UTI89 3992630 YP_539151.1 CDS yacF NC_007946.1 114179 114922 R hypothetical protein complement(114179..114922) Escherichia coli UTI89 3992631 YP_539152.1 CDS coaE NC_007946.1 114922 115542 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(114922..115542) Escherichia coli UTI89 3992632 YP_539153.1 CDS guaC NC_007946.1 115767 116810 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 115767..116810 Escherichia coli UTI89 3992633 YP_539154.1 CDS hofC NC_007946.1 116845 118047 R type IV pilin biogenesis protein complement(116845..118047) Escherichia coli UTI89 3992634 YP_539155.1 CDS hofB NC_007946.1 118037 119422 R hypothetical protein complement(118037..119422) Escherichia coli UTI89 3992635 YP_539156.1 CDS ppdD NC_007946.1 119432 119872 R major pilin subunit complement(119432..119872) Escherichia coli UTI89 3992636 YP_539157.1 CDS UTI89_C0116 NC_007946.1 119890 120063 D hypothetical protein 119890..120063 Escherichia coli UTI89 3992637 YP_539158.2 CDS nadC NC_007946.1 120076 120969 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(120076..120969) Escherichia coli UTI89 3993332 YP_539159.1 CDS ampD NC_007946.1 121057 121608 D N-acetyl-anhydromuranmyl-L-alanine amidase 121057..121608 Escherichia coli UTI89 3993333 YP_539160.1 CDS ampE NC_007946.1 121605 122459 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 121605..122459 Escherichia coli UTI89 3993334 YP_539161.1 CDS aroP NC_007946.1 122502 123872 R aromatic amino acid transporter complement(122502..123872) Escherichia coli UTI89 3993335 YP_539162.1 CDS usp NC_007946.1 124400 126181 D uropathogenic specific protein 124400..126181 Escherichia coli UTI89 3993336 YP_539163.1 CDS UTI89_C0122 NC_007946.1 126184 126468 D hypothetical protein 126184..126468 Escherichia coli UTI89 3993337 YP_539164.1 CDS UTI89_C0123 NC_007946.1 126876 127166 D hypothetical protein 126876..127166 Escherichia coli UTI89 3993338 YP_539165.1 CDS UTI89_C0124 NC_007946.1 127575 127865 D hypothetical protein 127575..127865 Escherichia coli UTI89 3993339 YP_539166.2 CDS pdhR NC_007946.1 128321 129085 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 128321..129085 Escherichia coli UTI89 3993340 YP_539167.1 CDS UTI89_C0126 NC_007946.1 129082 129264 R hypothetical protein complement(129082..129264) Escherichia coli UTI89 3993341 YP_539168.1 CDS aceE NC_007946.1 129246 131909 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 129246..131909 Escherichia coli UTI89 3993342 YP_539169.1 CDS aceF NC_007946.1 131924 133816 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 131924..133816 Escherichia coli UTI89 3993343 YP_539170.2 CDS lpdA NC_007946.1 134024 135448 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 134024..135448 Escherichia coli UTI89 3993344 YP_539171.1 CDS yacH NC_007946.1 135690 137447 R hypothetical protein complement(135690..137447) Escherichia coli UTI89 3993345 YP_539172.2 CDS acnB NC_007946.1 137802 140399 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 137802..140399 Escherichia coli UTI89 3993346 YP_539173.2 CDS yacL NC_007946.1 140574 140936 D hypothetical protein 140574..140936 Escherichia coli UTI89 3993347 YP_539174.1 CDS speD NC_007946.1 140974 141768 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(140974..141768) Escherichia coli UTI89 3993348 YP_539175.1 CDS speE NC_007946.1 141784 142650 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(141784..142650) Escherichia coli UTI89 3993349 YP_539176.1 CDS yacC NC_007946.1 142756 143274 R hypothetical protein complement(142756..143274) Escherichia coli UTI89 3993350 YP_539177.2 CDS cueO NC_007946.1 143269 144819 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 143269..144819 Escherichia coli UTI89 3992950 YP_539178.1 CDS gcd NC_007946.1 144866 147274 R glucose dehydrogenase complement(144866..147274) Escherichia coli UTI89 3992951 YP_539179.1 CDS hpt NC_007946.1 147423 147998 D hypoxanthine phosphoribosyltransferase 147423..147998 Escherichia coli UTI89 3992952 YP_539180.1 CDS yadF NC_007946.1 148039 148701 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(148039..148701) Escherichia coli UTI89 3992953 YP_539181.1 CDS yadG NC_007946.1 148810 149736 D hypothetical protein 148810..149736 Escherichia coli UTI89 3992954 YP_539182.1 CDS yadH NC_007946.1 149733 150503 D ABC transporter 149733..150503 Escherichia coli UTI89 3992955 YP_539183.1 CDS yadI NC_007946.1 150608 151048 D PTS system IIA component YadI 150608..151048 Escherichia coli UTI89 3992956 YP_539184.1 CDS yadE NC_007946.1 151112 152341 D hypothetical protein 151112..152341 Escherichia coli UTI89 3992957 YP_539185.1 CDS panD NC_007946.1 152345 152725 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(152345..152725) Escherichia coli UTI89 3992958 YP_539186.1 CDS UTI89_C0145 NC_007946.1 152693 152878 D hypothetical protein 152693..152878 Escherichia coli UTI89 3992959 YP_539187.1 CDS yadD NC_007946.1 152999 153883 D hypothetical protein 152999..153883 Escherichia coli UTI89 3992960 YP_539188.1 CDS panC NC_007946.1 153965 154816 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(153965..154816) Escherichia coli UTI89 3992961 YP_539189.1 CDS panB NC_007946.1 154828 155622 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(154828..155622) Escherichia coli UTI89 3992962 YP_539190.1 CDS yadC NC_007946.1 155734 157023 R fimbrial-like adhesin protein complement(155734..157023) Escherichia coli UTI89 3992963 YP_539191.1 CDS yadK NC_007946.1 157049 157645 R fimbrial subunit YadK complement(157049..157645) Escherichia coli UTI89 3992964 YP_539192.1 CDS yadL NC_007946.1 157672 158286 R fimbrial subunit YadL complement(157672..158286) Escherichia coli UTI89 3992965 YP_539193.1 CDS yadM NC_007946.1 158292 158858 R fimbrial subunit YadM complement(158292..158858) Escherichia coli UTI89 3992966 YP_539194.1 CDS htrE NC_007946.1 158875 161463 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(158875..161463) Escherichia coli UTI89 3992967 YP_539195.1 CDS ecpD NC_007946.1 161498 162238 R chaperone protein EcpD complement(161498..162238) Escherichia coli UTI89 3992968 YP_539196.1 CDS yadN NC_007946.1 162347 162961 R fimbrial subunit YadN complement(162347..162961) Escherichia coli UTI89 3992969 YP_539197.1 CDS folK NC_007946.1 163299 163778 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(163299..163778) Escherichia coli UTI89 3993233 YP_539198.1 CDS pcnB NC_007946.1 163775 165193 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase complement(163775..165193) Escherichia coli UTI89 3993234 YP_539199.2 CDS yadB NC_007946.1 165232 166128 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(165232..166128) Escherichia coli UTI89 3993235 YP_539200.2 CDS dksA NC_007946.1 166195 166650 R RNA polymerase-binding transcription factor complement(166195..166650) Escherichia coli UTI89 3993236 YP_539201.1 CDS sfsA NC_007946.1 166828 167532 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(166828..167532) Escherichia coli UTI89 3993237 YP_539202.1 CDS ligT NC_007946.1 167547 168086 R 2'-5' RNA ligase complement(167547..168086) Escherichia coli UTI89 3993238 YP_539203.1 CDS hrpB NC_007946.1 168106 170580 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 168106..170580 Escherichia coli UTI89 3993239 YP_539204.1 CDS UTI89_C0163 NC_007946.1 170508 170675 R hypothetical protein complement(170508..170675) Escherichia coli UTI89 3993240 YP_539205.1 CDS mrcB NC_007946.1 170674 173208 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 170674..173208 Escherichia coli UTI89 3993241 YP_539206.1 CDS UTI89_C0165 NC_007946.1 173273 173455 R hypothetical protein complement(173273..173455) Escherichia coli UTI89 3993242 YP_539207.1 CDS fhuA NC_007946.1 173428 175671 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 173428..175671 Escherichia coli UTI89 3993243 YP_539208.2 CDS fhuC NC_007946.1 175722 176519 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 175722..176519 Escherichia coli UTI89 3993244 YP_539209.1 CDS fhuD NC_007946.1 176516 177409 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 176516..177409 Escherichia coli UTI89 3993245 YP_539210.1 CDS fhuB NC_007946.1 177406 179388 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 177406..179388 Escherichia coli UTI89 3993246 YP_539211.1 CDS hemL NC_007946.1 179423 180703 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(179423..180703) Escherichia coli UTI89 3993247 YP_539212.1 CDS yadQ NC_007946.1 180928 182349 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 180928..182349 Escherichia coli UTI89 3993248 YP_539213.1 CDS yadR NC_007946.1 182398 182775 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 182398..182775 Escherichia coli UTI89 3993249 YP_539214.1 CDS yadS NC_007946.1 182822 183445 R hypothetical protein complement(182822..183445) Escherichia coli UTI89 3993250 YP_539215.1 CDS yadT NC_007946.1 183483 184283 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(183483..184283) Escherichia coli UTI89 3993251 YP_539216.1 CDS mtn NC_007946.1 184276 184974 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(184276..184974) Escherichia coli UTI89 3992489 YP_539217.1 CDS dgt NC_007946.1 185058 186575 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 185058..186575 Escherichia coli UTI89 3992490 YP_539218.1 CDS degP NC_007946.1 186705 188129 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 186705..188129 Escherichia coli UTI89 3992491 YP_539219.1 CDS cdaR NC_007946.1 188307 189437 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 188307..189437 Escherichia coli UTI89 3992492 YP_539220.1 CDS yaeH NC_007946.1 189491 189877 R hypothetical protein complement(189491..189877) Escherichia coli UTI89 3992493 YP_539221.1 CDS dapD NC_007946.1 190189 191013 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(190189..191013) Escherichia coli UTI89 3992494 YP_539222.1 CDS glnD NC_007946.1 191044 193716 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(191044..193716) Escherichia coli UTI89 3992495 YP_539223.1 CDS map NC_007946.1 193778 194572 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(193778..194572) Escherichia coli UTI89 3992496 YP_539224.2 CDS rpsB NC_007946.1 194940 195665 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 194940..195665 Escherichia coli UTI89 3992497 YP_539225.1 CDS UTI89_C0184 NC_007946.1 195617 196546 R hypothetical protein complement(195617..196546) Escherichia coli UTI89 3992498 YP_539226.1 CDS tsf NC_007946.1 195800 196651 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 195800..196651 Escherichia coli UTI89 3992499 YP_539227.1 CDS pyrH NC_007946.1 196798 197523 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 196798..197523 Escherichia coli UTI89 3992500 YP_539228.1 CDS frr NC_007946.1 197673 198230 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 197673..198230 Escherichia coli UTI89 3992501 YP_539229.1 CDS dxr NC_007946.1 198322 199518 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 198322..199518 Escherichia coli UTI89 3992502 YP_539230.1 CDS uppS NC_007946.1 199704 200465 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 199704..200465 Escherichia coli UTI89 3992503 YP_539231.1 CDS cdsA NC_007946.1 200478 201335 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 200478..201335 Escherichia coli UTI89 3992504 YP_539232.1 CDS ecfE NC_007946.1 201302 202699 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 201302..202699 Escherichia coli UTI89 3992505 YP_539233.1 CDS ecfK NC_007946.1 202729 205161 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 202729..205161 Escherichia coli UTI89 3992506 YP_539234.1 CDS hlpA NC_007946.1 205283 205768 D periplasmic chaperone 205283..205768 Escherichia coli UTI89 3992507 YP_539235.1 CDS lpxD NC_007946.1 205772 206797 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 205772..206797 Escherichia coli UTI89 3992508 YP_539236.1 CDS fabZ NC_007946.1 206809 207357 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 206809..207357 Escherichia coli UTI89 3994667 YP_539237.1 CDS lpxA NC_007946.1 207361 208149 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 207361..208149 Escherichia coli UTI89 3994668 YP_539238.1 CDS lpxB NC_007946.1 208149 209297 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 208149..209297 Escherichia coli UTI89 3994669 YP_539239.1 CDS rnhB NC_007946.1 209294 209890 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 209294..209890 Escherichia coli UTI89 3994670 YP_539240.1 CDS dnaE NC_007946.1 209927 213409 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 209927..213409 Escherichia coli UTI89 3994671 YP_539241.1 CDS accA NC_007946.1 213422 214381 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 213422..214381 Escherichia coli UTI89 3994672 YP_539242.1 CDS ldcC NC_007946.1 214479 216620 D lysine decarboxylase, constitutive 214479..216620 Escherichia coli UTI89 3994673 YP_539243.2 CDS yaeR NC_007946.1 216677 217066 D hypothetical protein 216677..217066 Escherichia coli UTI89 3994674 YP_539244.1 CDS tilS NC_007946.1 217131 218429 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 217131..218429 Escherichia coli UTI89 3994675 YP_539245.1 CDS rof NC_007946.1 218477 218737 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(218477..218737) Escherichia coli UTI89 3994676 YP_539246.1 CDS yaeP NC_007946.1 218724 218942 R hypothetical protein complement(218724..218942) Escherichia coli UTI89 3994677 YP_539247.1 CDS yaeQ NC_007946.1 219090 219635 D hypothetical protein 219090..219635 Escherichia coli UTI89 3994678 YP_539248.1 CDS yaeJ NC_007946.1 219632 220054 D peptidyl-tRNA hydrolase domain-containing protein 219632..220054 Escherichia coli UTI89 3994679 YP_539249.1 CDS cutF NC_007946.1 220068 220778 D lipoprotein involved with copper homeostasis and adhesion 220068..220778 Escherichia coli UTI89 3994680 YP_539250.2 CDS yaeF NC_007946.1 220934 221758 R hypothetical protein complement(220934..221758) Escherichia coli UTI89 3994681 YP_539251.2 CDS proS NC_007946.1 221811 223529 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(221811..223529) Escherichia coli UTI89 3994682 YP_539252.1 CDS yaeB NC_007946.1 223640 224347 R hypothetical protein complement(223640..224347) Escherichia coli UTI89 3994683 YP_539253.1 CDS rcsF NC_007946.1 224344 224748 R outer membrane lipoprotein complement(224344..224748) Escherichia coli UTI89 3994684 YP_539254.1 CDS metQ NC_007946.1 224866 225681 R DL-methionine transporter substrate-binding subunit complement(224866..225681) Escherichia coli UTI89 3994685 YP_539255.1 CDS metI NC_007946.1 225721 226374 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit complement(225721..226374) Escherichia coli UTI89 3994574 YP_539256.1 CDS metN NC_007946.1 226367 227398 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(226367..227398) Escherichia coli UTI89 3994575 YP_539257.1 CDS yaeD NC_007946.1 227586 228158 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 227586..228158 Escherichia coli UTI89 3994576 YP_539261.1 CDS dkgB NC_007946.1 233915 234718 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 233915..234718 Escherichia coli UTI89 3994586 YP_539262.1 CDS UTI89_C0227 NC_007946.1 234715 235629 R LysR family transcriptional regulator complement(234715..235629) Escherichia coli UTI89 3994587 YP_539263.1 CDS yafD NC_007946.1 235846 236670 D hypothetical protein 235846..236670 Escherichia coli UTI89 3992085 YP_539264.1 CDS yafE NC_007946.1 236748 237518 D hypothetical protein 236748..237518 Escherichia coli UTI89 3992086 YP_539265.1 CDS mltD NC_007946.1 237565 238923 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(237565..238923) Escherichia coli UTI89 3992087 YP_539266.1 CDS gloB NC_007946.1 238995 239750 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(238995..239750) Escherichia coli UTI89 3992088 YP_539267.1 CDS yafS NC_007946.1 239766 240506 D hypothetical protein 239766..240506 Escherichia coli UTI89 3992089 YP_539268.1 CDS rnhA NC_007946.1 240503 241081 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(240503..241081) Escherichia coli UTI89 3992090 YP_539269.1 CDS dnaQ NC_007946.1 241026 241766 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 241026..241766 Escherichia coli UTI89 3992091 YP_539270.1 CDS yafT NC_007946.1 242304 243089 D aminopeptidase 242304..243089 Escherichia coli UTI89 3992093 YP_539271.1 CDS UTI89_C0237 NC_007946.1 243429 243908 R hypothetical protein complement(243429..243908) Escherichia coli UTI89 3992094 YP_539272.1 CDS UTI89_C0238 NC_007946.1 243926 245368 R hypothetical protein complement(243926..245368) Escherichia coli UTI89 3992095 YP_539273.1 CDS UTI89_C0239 NC_007946.1 245295 248762 R hypothetical protein complement(245295..248762) Escherichia coli UTI89 3992096 YP_539274.1 CDS UTI89_C0240 NC_007946.1 248842 250284 R hypothetical protein complement(248842..250284) Escherichia coli UTI89 3992097 YP_539275.1 CDS UTI89_C0241 NC_007946.1 250289 251032 R hypothetical protein complement(250289..251032) Escherichia coli UTI89 3992098 YP_539276.1 CDS UTI89_C0242 NC_007946.1 251029 253788 R hypothetical protein complement(251029..253788) Escherichia coli UTI89 3992099 YP_539277.1 CDS UTI89_C0243 NC_007946.1 253798 254562 R hypothetical protein complement(253798..254562) Escherichia coli UTI89 3992100 YP_539278.1 CDS UTI89_C0244 NC_007946.1 254567 255913 R hypothetical protein complement(254567..255913) Escherichia coli UTI89 3992101 YP_539279.1 CDS UTI89_C0245 NC_007946.1 255916 256440 R hypothetical protein complement(255916..256440) Escherichia coli UTI89 3992102 YP_539280.1 CDS UTI89_C0246 NC_007946.1 256437 257729 R hypothetical protein complement(256437..257729) Escherichia coli UTI89 3993985 YP_539281.1 CDS UTI89_C0247 NC_007946.1 257734 258783 R hypothetical protein complement(257734..258783) Escherichia coli UTI89 3993986 YP_539282.1 CDS UTI89_C0248 NC_007946.1 258747 260588 R hypothetical protein complement(258747..260588) Escherichia coli UTI89 3993987 YP_539283.1 CDS UTI89_C0249 NC_007946.1 260594 261019 R hypothetical protein complement(260594..261019) Escherichia coli UTI89 3993988 YP_539284.1 CDS UTI89_C0250 NC_007946.1 261024 262508 R hypothetical protein complement(261024..262508) Escherichia coli UTI89 3993989 YP_539285.1 CDS UTI89_C0251 NC_007946.1 262531 263034 R hypothetical protein complement(262531..263034) Escherichia coli UTI89 3993990 YP_539286.1 CDS UTI89_C0252 NC_007946.1 263740 264258 D hypothetical protein 263740..264258 Escherichia coli UTI89 3993991 YP_539287.1 CDS UTI89_C0253 NC_007946.1 264479 266461 D hypothetical protein 264479..266461 Escherichia coli UTI89 3993992 YP_539288.1 CDS UTI89_C0254 NC_007946.1 266568 267614 D hypothetical protein 266568..267614 Escherichia coli UTI89 3993993 YP_539289.1 CDS UTI89_C0255 NC_007946.1 267607 269046 D hypothetical protein 267607..269046 Escherichia coli UTI89 3993994 YP_539290.1 CDS UTI89_C0256 NC_007946.1 269021 269311 D hypothetical protein 269021..269311 Escherichia coli UTI89 3993995 YP_539291.1 CDS UTI89_C0257 NC_007946.1 270562 271065 D hypothetical protein 270562..271065 Escherichia coli UTI89 3993996 YP_539292.1 CDS UTI89_C0258 NC_007946.1 271135 271647 D hypothetical protein 271135..271647 Escherichia coli UTI89 3993997 YP_539293.1 CDS UTI89_C0259 NC_007946.1 271918 272697 R hypothetical protein complement(271918..272697) Escherichia coli UTI89 3993998 YP_539294.1 CDS ykfE NC_007946.1 272842 273315 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 272842..273315 Escherichia coli UTI89 3993999 YP_539295.2 CDS fadE NC_007946.1 273358 275802 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(273358..275802) Escherichia coli UTI89 3994000 YP_539296.2 CDS gmhA NC_007946.1 276042 276620 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 276042..276620 Escherichia coli UTI89 3994001 YP_539297.1 CDS yafJ NC_007946.1 276810 277592 D amidotransferase 276810..277592 Escherichia coli UTI89 3994002 YP_539298.1 CDS yafK NC_007946.1 277563 278303 R hypothetical protein complement(277563..278303) Escherichia coli UTI89 3994003 YP_539299.1 CDS UTI89_C0265 NC_007946.1 278560 278697 R hypothetical protein complement(278560..278697) Escherichia coli UTI89 3994004 YP_539300.1 CDS yafL NC_007946.1 278672 279364 D lipoprotein YafL 278672..279364 Escherichia coli UTI89 3990094 YP_539301.1 CDS yafM NC_007946.1 279540 280037 D hypothetical protein 279540..280037 Escherichia coli UTI89 3990095 YP_539302.1 CDS UTI89_C0268 NC_007946.1 280120 280329 R hypothetical protein complement(280120..280329) Escherichia coli UTI89 3990096 YP_539303.1 CDS fhiA NC_007946.1 280357 282096 R FhiA protein complement(280357..282096) Escherichia coli UTI89 3990097 YP_539304.1 CDS mbhA NC_007946.1 282038 282826 D hypothetical protein 282038..282826 Escherichia coli UTI89 3990098 YP_539305.1 CDS dinP NC_007946.1 282897 283952 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 282897..283952 Escherichia coli UTI89 3990099 YP_539306.1 CDS yafN NC_007946.1 284004 284297 D antitoxin of the YafO-YafN toxin-antitoxin system 284004..284297 Escherichia coli UTI89 3990100 YP_539307.1 CDS yafO NC_007946.1 284300 284698 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 284300..284698 Escherichia coli UTI89 3990101 YP_539308.1 CDS yafP NC_007946.1 284708 285160 D hypothetical protein 284708..285160 Escherichia coli UTI89 3990102 YP_539309.1 CDS UTI89_C0275 NC_007946.1 285338 286489 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 285338..286489 Escherichia coli UTI89 3990103 YP_539310.2 CDS prfH NC_007946.1 286600 287100 D similar to release factor 1 and 2; peptide chain release factor-like protein 286600..287100 Escherichia coli UTI89 3990104 YP_539311.1 CDS pepD NC_007946.1 287157 288614 R aminoacyl-histidine dipeptidase complement(287157..288614) Escherichia coli UTI89 3990105 YP_539312.1 CDS gpt NC_007946.1 288875 289333 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 288875..289333 Escherichia coli UTI89 3990106 YP_539313.1 CDS UTI89_C0279 NC_007946.1 289007 289459 R hypothetical protein complement(289007..289459) Escherichia coli UTI89 3990107 YP_539314.1 CDS frsA NC_007946.1 289425 290669 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 289425..290669 Escherichia coli UTI89 3990108 YP_539315.1 CDS crl NC_007946.1 290727 291128 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 290727..291128 Escherichia coli UTI89 3990109 YP_539316.1 CDS phoE NC_007946.1 291238 292299 R outer membrane phosphoporin protein E complement(291238..292299) Escherichia coli UTI89 3990110 YP_539317.2 CDS proB NC_007946.1 292582 293685 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 292582..293685 Escherichia coli UTI89 3990111 YP_539318.1 CDS proA NC_007946.1 293697 294950 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 293697..294950 Escherichia coli UTI89 3990112 YP_539319.1 CDS UTI89_C0286 NC_007946.1 295228 297168 D integrase 295228..297168 Escherichia coli UTI89 3993776 YP_539320.1 CDS UTI89_C0287 NC_007946.1 297292 297624 R hypothetical protein complement(297292..297624) Escherichia coli UTI89 3993777 YP_539321.1 CDS UTI89_C0288 NC_007946.1 297787 299625 R similar to pathogenesis-related protein; hypothetical protein complement(297787..299625) Escherichia coli UTI89 3993778 YP_539322.1 CDS UTI89_C0289 NC_007946.1 299622 301769 R hypothetical protein complement(299622..301769) Escherichia coli UTI89 3993779 YP_539323.1 CDS UTI89_C0290 NC_007946.1 302117 302680 D resolvase 302117..302680 Escherichia coli UTI89 3993780 YP_539324.1 CDS UTI89_C0291 NC_007946.1 302838 303335 R hypothetical protein complement(302838..303335) Escherichia coli UTI89 3993781 YP_539325.1 CDS UTI89_C0292 NC_007946.1 303574 304038 D transcription regulator 303574..304038 Escherichia coli UTI89 3993782 YP_539326.1 CDS UTI89_C0293 NC_007946.1 304545 305459 R hypothetical protein complement(304545..305459) Escherichia coli UTI89 3993783 YP_539327.1 CDS UTI89_C0295 NC_007946.1 305929 306267 D CP4-like integrase 305929..306267 Escherichia coli UTI89 3993785 YP_539328.1 CDS UTI89_C0296 NC_007946.1 305979 306371 R hypothetical protein complement(305979..306371) Escherichia coli UTI89 3993786 YP_539329.1 CDS UTI89_C0297 NC_007946.1 306702 307226 R hypothetical protein complement(306702..307226) Escherichia coli UTI89 3993787 YP_539330.1 CDS UTI89_C0298 NC_007946.1 311796 311993 D hypothetical protein 311796..311993 Escherichia coli UTI89 3993788 YP_539331.1 CDS insA NC_007946.1 312076 312291 D InsA protein 312076..312291 Escherichia coli UTI89 3993789 YP_539332.1 CDS insB NC_007946.1 312482 312757 R hypothetical protein complement(312482..312757) Escherichia coli UTI89 3993790 YP_539333.1 CDS UTI89_C0301 NC_007946.1 312593 312769 D InsB protein 312593..312769 Escherichia coli UTI89 3993791 YP_539334.1 CDS UTI89_C0302 NC_007946.1 313148 313378 D hypothetical protein 313148..313378 Escherichia coli UTI89 3993792 YP_539335.1 CDS yagU NC_007946.1 313593 314207 D hypothetical protein 313593..314207 Escherichia coli UTI89 3994040 YP_539336.1 CDS ykgJ NC_007946.1 314456 314785 R ferredoxin complement(314456..314785) Escherichia coli UTI89 3994041 YP_539337.1 CDS yagV NC_007946.1 315092 315847 R hypothetical protein complement(315092..315847) Escherichia coli UTI89 3994042 YP_539338.1 CDS yagW NC_007946.1 315771 317414 R hypothetical protein complement(315771..317414) Escherichia coli UTI89 3994043 YP_539339.1 CDS yagX NC_007946.1 317404 319929 R hypothetical protein complement(317404..319929) Escherichia coli UTI89 3994044 YP_539340.1 CDS yagY NC_007946.1 319955 320671 R hypothetical protein complement(319955..320671) Escherichia coli UTI89 3994045 YP_539341.1 CDS matB NC_007946.1 320680 321297 R MatB complement(320680..321297) Escherichia coli UTI89 3994046 YP_539342.1 CDS matA NC_007946.1 321340 321930 R hypothetical protein complement(321340..321930) Escherichia coli UTI89 3994047 YP_539343.1 CDS UTI89_C0311 NC_007946.1 322335 322559 R hypothetical protein complement(322335..322559) Escherichia coli UTI89 3994048 YP_539344.1 CDS UTI89_C0312 NC_007946.1 322354 322644 D hypothetical protein 322354..322644 Escherichia coli UTI89 3994049 YP_539345.1 CDS rpmJ NC_007946.1 322966 323109 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(322966..323109) Escherichia coli UTI89 3994050 YP_539346.2 CDS rpmE2 NC_007946.1 323106 323369 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(323106..323369) Escherichia coli UTI89 3994051 YP_539347.1 CDS UTI89_C0315 NC_007946.1 324309 325451 R NADH-dependent flavin oxidoreductase complement(324309..325451) Escherichia coli UTI89 3994052 YP_539348.1 CDS ycjY NC_007946.1 325623 326543 R hypothetical protein complement(325623..326543) Escherichia coli UTI89 3994053 YP_539349.1 CDS UTI89_C0317 NC_007946.1 326637 327626 D LysR family transcriptional regulator 326637..327626 Escherichia coli UTI89 3994054 YP_539350.1 CDS ycjZ NC_007946.1 327751 328719 D transcriptional regulator YcjZ 327751..328719 Escherichia coli UTI89 3994055 YP_539351.1 CDS UTI89_C0319 NC_007946.1 328750 329739 R aldo/keto reductase complement(328750..329739) Escherichia coli UTI89 3994056 YP_539352.1 CDS UTI89_C0320 NC_007946.1 329766 330617 R 2,5-diketo-D-gluconate reductase A complement(329766..330617) Escherichia coli UTI89 3994057 YP_539353.1 CDS eaeH NC_007946.1 331183 335433 D attaching and effacing protein, pathogenesis factor 331183..335433 Escherichia coli UTI89 3994058 YP_539354.1 CDS ykgA NC_007946.1 335558 336448 R transcriptional regulator YkgA complement(335558..336448) Escherichia coli UTI89 3990710 YP_539355.1 CDS UTI89_C0323 NC_007946.1 336648 337532 D 2,5-diketo-D-gluconate reductase A 336648..337532 Escherichia coli UTI89 3990711 YP_539356.1 CDS ykgB NC_007946.1 337692 338294 R hypothetical protein complement(337692..338294) Escherichia coli UTI89 3990712 YP_539358.1 CDS ykgI NC_007946.1 338297 338548 R hypothetical protein complement(338297..338548) Escherichia coli UTI89 3990714 YP_539359.2 CDS ykgC NC_007946.1 338642 339967 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(338642..339967) Escherichia coli UTI89 3990715 YP_539360.1 CDS ykgD NC_007946.1 340143 341048 D transcriptional regulator YkgD 340143..341048 Escherichia coli UTI89 3990716 YP_539361.1 CDS ykgE NC_007946.1 341575 342294 D hypothetical protein 341575..342294 Escherichia coli UTI89 3990717 YP_539362.1 CDS ykgF NC_007946.1 342305 343732 D electron transport protein YkgF 342305..343732 Escherichia coli UTI89 3990718 YP_539363.1 CDS ykgG NC_007946.1 343572 344420 D hypothetical protein 343572..344420 Escherichia coli UTI89 3990719 YP_539364.1 CDS UTI89_C0332 NC_007946.1 344375 344587 R hypothetical protein complement(344375..344587) Escherichia coli UTI89 3990720 YP_539365.1 CDS ykgH NC_007946.1 344662 345330 R hypothetical protein complement(344662..345330) Escherichia coli UTI89 3990721 YP_539366.1 CDS UTI89_C0334 NC_007946.1 345514 347844 R hypothetical protein complement(345514..347844) Escherichia coli UTI89 3990722 YP_539367.1 CDS UTI89_C0335 NC_007946.1 347853 348614 R hypothetical protein complement(347853..348614) Escherichia coli UTI89 3990723 YP_539368.1 CDS UTI89_C0336 NC_007946.1 348768 349472 R hypothetical protein complement(348768..349472) Escherichia coli UTI89 3990724 YP_539369.1 CDS UTI89_C0337 NC_007946.1 349444 349599 R hypothetical protein complement(349444..349599) Escherichia coli UTI89 3990725 YP_539370.1 CDS fimX NC_007946.1 349892 350494 R type 1 fimbriae regulatory protein FimX complement(349892..350494) Escherichia coli UTI89 3990726 YP_539371.1 CDS UTI89_C0339 NC_007946.1 351273 351500 D hypothetical protein 351273..351500 Escherichia coli UTI89 3990727 YP_539372.2 CDS betA NC_007946.1 351525 353213 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(351525..353213) Escherichia coli UTI89 3990728 YP_539373.1 CDS betB NC_007946.1 353227 354702 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(353227..354702) Escherichia coli UTI89 3990729 YP_539374.1 CDS betI NC_007946.1 354713 355318 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(354713..355318) Escherichia coli UTI89 3992181 YP_539375.1 CDS betT NC_007946.1 355429 357462 D proton-motive-force-driven choline transporter; choline transport protein BetT 355429..357462 Escherichia coli UTI89 3992182 YP_539376.1 CDS yahA NC_007946.1 358334 359428 D hypothetical protein 358334..359428 Escherichia coli UTI89 3992183 YP_539377.1 CDS yahB NC_007946.1 359470 360402 R transcriptional regulator YahB complement(359470..360402) Escherichia coli UTI89 3992184 YP_539378.1 CDS yahC NC_007946.1 360494 360991 R hypothetical protein complement(360494..360991) Escherichia coli UTI89 3992185 YP_539379.1 CDS UTI89_C0347 NC_007946.1 361068 361310 D hypothetical protein 361068..361310 Escherichia coli UTI89 3992186 YP_539380.1 CDS yahD NC_007946.1 361249 361854 D transcription factor 361249..361854 Escherichia coli UTI89 3992187 YP_539381.1 CDS yahE NC_007946.1 361894 362757 D hypothetical protein 361894..362757 Escherichia coli UTI89 3992188 YP_539382.1 CDS yahF NC_007946.1 362747 364294 D hypothetical protein 362747..364294 Escherichia coli UTI89 3992189 YP_539383.1 CDS yahG NC_007946.1 364294 365712 D hypothetical protein 364294..365712 Escherichia coli UTI89 3992190 YP_539384.1 CDS yahI NC_007946.1 365866 366816 D carbamate kinase 365866..366816 Escherichia coli UTI89 3992191 YP_539385.1 CDS yahJ NC_007946.1 366826 368208 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 366826..368208 Escherichia coli UTI89 3992192 YP_539386.1 CDS UTI89_C0354 NC_007946.1 368476 368916 D hypothetical protein 368476..368916 Escherichia coli UTI89 3992193 YP_539387.1 CDS UTI89_C0355 NC_007946.1 369167 370153 D periplasmic binding protein, substrate ribose 369167..370153 Escherichia coli UTI89 3992194 YP_539388.1 CDS UTI89_C0356 NC_007946.1 370187 371686 D ABC transporter ATP-binding protein 370187..371686 Escherichia coli UTI89 3992195 YP_539389.1 CDS UTI89_C0357 NC_007946.1 371679 372650 D permease 371679..372650 Escherichia coli UTI89 3992196 YP_539390.1 CDS UTI89_C0358 NC_007946.1 372647 373603 D permease 372647..373603 Escherichia coli UTI89 3992197 YP_539391.1 CDS yahK NC_007946.1 373690 374739 D zinc-type alcohol dehydrogenase-like protein YahK 373690..374739 Escherichia coli UTI89 3992198 YP_539392.1 CDS yahM NC_007946.1 375331 375606 D hypothetical protein 375331..375606 Escherichia coli UTI89 3992199 YP_539393.1 CDS yahN NC_007946.1 375623 376294 R cytochrome subunit of dehydrogenase complement(375623..376294) Escherichia coli UTI89 3994383 YP_539394.1 CDS yahO NC_007946.1 376441 376716 D hypothetical protein 376441..376716 Escherichia coli UTI89 3994384 YP_539395.1 CDS prpB NC_007946.1 378642 379532 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 378642..379532 Escherichia coli UTI89 3994385 YP_539396.1 CDS prpC NC_007946.1 379577 380746 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 379577..380746 Escherichia coli UTI89 3994386 YP_539397.1 CDS prpD NC_007946.1 380780 382231 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 380780..382231 Escherichia coli UTI89 3994387 YP_539398.1 CDS prpE NC_007946.1 382271 384157 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 382271..384157 Escherichia coli UTI89 3994388 YP_539399.1 CDS codB NC_007946.1 384482 385741 D cytosine permease 384482..385741 Escherichia coli UTI89 3994389 YP_539400.1 CDS codA NC_007946.1 385716 387014 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 385716..387014 Escherichia coli UTI89 3994390 YP_539401.1 CDS lacA NC_007946.1 387135 387797 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(387135..387797) Escherichia coli UTI89 3994391 YP_539402.1 CDS lacY NC_007946.1 387812 389065 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(387812..389065) Escherichia coli UTI89 3994392 YP_539403.1 CDS lacZ NC_007946.1 389117 392191 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(389117..392191) Escherichia coli UTI89 3994393 YP_539404.1 CDS lacI NC_007946.1 392314 393405 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(392314..393405) Escherichia coli UTI89 3994394 YP_539405.1 CDS UTI89_C0373 NC_007946.1 393433 393531 R AraC family transcriptional regulator complement(393433..393531) Escherichia coli UTI89 3994395 YP_539406.1 CDS UTI89_C0374 NC_007946.1 393598 394137 D hypothetical protein 393598..394137 Escherichia coli UTI89 3994396 YP_539407.1 CDS yaiM NC_007946.1 394363 395196 R hypothetical protein complement(394363..395196) Escherichia coli UTI89 3994397 YP_539408.1 CDS adhC NC_007946.1 395289 396398 R alcohol dehydrogenase complement(395289..396398) Escherichia coli UTI89 3994398 YP_539409.1 CDS yaiN NC_007946.1 396433 396729 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(396433..396729) Escherichia coli UTI89 3994399 YP_539410.1 CDS UTI89_C0378 NC_007946.1 396478 396780 D hypothetical protein 396478..396780 Escherichia coli UTI89 3994400 YP_539411.1 CDS yaiO NC_007946.1 396897 397670 R hypothetical protein complement(396897..397670) Escherichia coli UTI89 3994401 YP_539412.1 CDS UTI89_C0380 NC_007946.1 397672 398196 R transferase complement(397672..398196) Escherichia coli UTI89 3994402 YP_539413.1 CDS yaiP NC_007946.1 398231 399427 R hypothetical protein complement(398231..399427) Escherichia coli UTI89 3992313 YP_539414.1 CDS UTI89_C0382 NC_007946.1 399437 400123 R hypothetical protein complement(399437..400123) Escherichia coli UTI89 3992314 YP_539415.1 CDS UTI89_C0383 NC_007946.1 400568 400762 R hypothetical protein complement(400568..400762) Escherichia coli UTI89 3992315 YP_539416.2 CDS tauA NC_007946.1 400716 401678 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 400716..401678 Escherichia coli UTI89 3992316 YP_539417.1 CDS tauB NC_007946.1 401691 402458 D Part of the ABC transporter complex tauABC involved in taurine import; taurine ABC transporter ATP-binding protein 401691..402458 Escherichia coli UTI89 3992317 YP_539418.1 CDS tauC NC_007946.1 402455 403282 D taurine ABC transporter 402455..403282 Escherichia coli UTI89 3992318 YP_539419.1 CDS tauD NC_007946.1 403279 404130 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 403279..404130 Escherichia coli UTI89 3992319 YP_539420.1 CDS hemB NC_007946.1 404170 405177 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(404170..405177) Escherichia coli UTI89 3992320 YP_539421.1 CDS UTI89_C0389 NC_007946.1 405670 408657 D structural protein 405670..408657 Escherichia coli UTI89 3992321 YP_539422.1 CDS yaiV NC_007946.1 408698 409366 D DNA-binding transcriptional regulator 408698..409366 Escherichia coli UTI89 3992322 YP_539423.1 CDS yaiH NC_007946.1 409367 410524 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(409367..410524) Escherichia coli UTI89 3992323 YP_539424.1 CDS UTI89_C0392 NC_007946.1 410662 410856 D hypothetical protein 410662..410856 Escherichia coli UTI89 3992324 YP_539425.1 CDS sbmA NC_007946.1 410870 412096 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 410870..412096 Escherichia coli UTI89 3992325 YP_539426.1 CDS yaiW NC_007946.1 412109 413203 D hypothetical protein 412109..413203 Escherichia coli UTI89 3992326 YP_539427.1 CDS yaiY NC_007946.1 413262 413570 R hypothetical protein complement(413262..413570) Escherichia coli UTI89 3992327 YP_539428.1 CDS UTI89_C0396 NC_007946.1 413500 413634 D hypothetical protein 413500..413634 Escherichia coli UTI89 3992328 YP_539429.1 CDS yaiZ NC_007946.1 413698 414042 D hypothetical protein 413698..414042 Escherichia coli UTI89 3992329 YP_539430.1 CDS ddl NC_007946.1 414066 415160 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(414066..415160) Escherichia coli UTI89 3992330 YP_539431.1 CDS UTI89_C0399 NC_007946.1 415238 415360 D hypothetical protein 415238..415360 Escherichia coli UTI89 3992331 YP_539432.1 CDS UTI89_C0400 NC_007946.1 415475 415738 R hypothetical protein complement(415475..415738) Escherichia coli UTI89 3993501 YP_539433.1 CDS yaiB NC_007946.1 415623 415883 D hypothetical protein 415623..415883 Escherichia coli UTI89 3993502 YP_539434.1 CDS phoA NC_007946.1 415915 417399 D alkaline phosphatase 415915..417399 Escherichia coli UTI89 3993503 YP_539435.1 CDS psiF NC_007946.1 417500 417838 D hypothetical protein 417500..417838 Escherichia coli UTI89 3993504 YP_539436.1 CDS adrA NC_007946.1 417940 419055 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 417940..419055 Escherichia coli UTI89 3993505 YP_539437.2 CDS proC NC_007946.1 419072 419881 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(419072..419881) Escherichia coli UTI89 3993506 YP_539438.1 CDS yaiI NC_007946.1 419881 420459 D hypothetical protein 419881..420459 Escherichia coli UTI89 3993507 YP_539439.1 CDS aroL NC_007946.1 420642 421166 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 420642..421166 Escherichia coli UTI89 3993508 YP_539440.1 CDS UTI89_C0408 NC_007946.1 421156 421488 R hypothetical protein complement(421156..421488) Escherichia coli UTI89 3993509 YP_539441.1 CDS yaiA NC_007946.1 421216 421407 D hypothetical protein 421216..421407 Escherichia coli UTI89 3993510 YP_539442.1 CDS aroM NC_007946.1 421665 422342 D hypothetical protein 421665..422342 Escherichia coli UTI89 3993511 YP_539443.1 CDS yaiE NC_007946.1 422414 422698 D hypothetical protein 422414..422698 Escherichia coli UTI89 3993512 YP_539444.1 CDS UTI89_C0412 NC_007946.1 422802 422957 R hypothetical protein complement(422802..422957) Escherichia coli UTI89 3993513 YP_539445.1 CDS ykiA NC_007946.1 422906 423187 D hypothetical protein 422906..423187 Escherichia coli UTI89 3993514 YP_539446.2 CDS rdgC NC_007946.1 423345 424256 R Required for efficient pilin antigenic variation; recombination associated protein complement(423345..424256) Escherichia coli UTI89 3993515 YP_539447.2 CDS yajF NC_007946.1 424381 425289 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 424381..425289 Escherichia coli UTI89 3993516 YP_539448.1 CDS araJ NC_007946.1 425558 426826 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(425558..426826) Escherichia coli UTI89 3993517 YP_539449.1 CDS sbcC NC_007946.1 426868 430011 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC complement(426868..430011) Escherichia coli UTI89 3993518 YP_539450.1 CDS sbcD NC_007946.1 430008 431210 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD complement(430008..431210) Escherichia coli UTI89 3993519 YP_539451.1 CDS UTI89_C0419 NC_007946.1 431196 431327 D hypothetical protein 431196..431327 Escherichia coli UTI89 3993520 YP_539452.1 CDS phoB NC_007946.1 431400 432089 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 431400..432089 Escherichia coli UTI89 3993718 YP_539453.1 CDS phoR NC_007946.1 432147 433442 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 432147..433442 Escherichia coli UTI89 3993719 YP_539454.1 CDS UTI89_C0422 NC_007946.1 433655 433804 R hypothetical protein complement(433655..433804) Escherichia coli UTI89 3993720 YP_539455.1 CDS brnQ NC_007946.1 433849 435168 D branched-chain amino acid transport system II carrier protein 433849..435168 Escherichia coli UTI89 3993721 YP_539456.1 CDS proY NC_007946.1 435241 436617 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; permease 435241..436617 Escherichia coli UTI89 3993722 YP_539457.1 CDS malZ NC_007946.1 436773 438590 D maltodextrin glucosidase 436773..438590 Escherichia coli UTI89 3993723 YP_539458.2 CDS yajB NC_007946.1 438595 439176 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase complement(438595..439176) Escherichia coli UTI89 3993724 YP_539459.1 CDS queA NC_007946.1 439395 440465 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 439395..440465 Escherichia coli UTI89 3993725 YP_539460.1 CDS tgt NC_007946.1 440520 441647 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 440520..441647 Escherichia coli UTI89 3993726 YP_539461.2 CDS yajC NC_007946.1 441670 442002 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 441670..442002 Escherichia coli UTI89 3993727 YP_539462.1 CDS secD NC_007946.1 442030 443877 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 442030..443877 Escherichia coli UTI89 3993728 YP_539463.1 CDS secF NC_007946.1 443843 444859 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 443843..444859 Escherichia coli UTI89 3993729 YP_539464.1 CDS yajD NC_007946.1 444920 445336 D hypothetical protein 444920..445336 Escherichia coli UTI89 3993730 YP_539465.1 CDS tsx NC_007946.1 445374 446306 R nucleoside channel phage T6/colicin K receptor complement(445374..446306) Escherichia coli UTI89 3993731 YP_539466.2 CDS yajI NC_007946.1 446556 447095 R hypothetical protein complement(446556..447095) Escherichia coli UTI89 3993732 YP_539467.1 CDS nrdR NC_007946.1 447246 447695 D transcriptional regulator NrdR 447246..447695 Escherichia coli UTI89 3993733 YP_539468.1 CDS ribD NC_007946.1 447699 448802 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 447699..448802 Escherichia coli UTI89 3993734 YP_539469.2 CDS ribH NC_007946.1 448891 449361 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 448891..449361 Escherichia coli UTI89 3993735 YP_539470.1 CDS UTI89_C0438 NC_007946.1 449351 449884 R hypothetical protein complement(449351..449884) Escherichia coli UTI89 3993736 YP_539471.1 CDS nusB NC_007946.1 449381 449800 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 449381..449800 Escherichia coli UTI89 3993082 YP_539472.1 CDS thiL NC_007946.1 449878 450855 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 449878..450855 Escherichia coli UTI89 3993083 YP_539473.1 CDS pgpA NC_007946.1 450833 451351 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 450833..451351 Escherichia coli UTI89 3993084 YP_539474.1 CDS yajO NC_007946.1 451405 452379 R oxidoreductase YajO complement(451405..452379) Escherichia coli UTI89 3993085 YP_539475.1 CDS dxs NC_007946.1 452434 454296 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(452434..454296) Escherichia coli UTI89 3993086 YP_539476.1 CDS ispA NC_007946.1 454321 455220 R geranyltranstransferase complement(454321..455220) Escherichia coli UTI89 3993087 YP_539477.1 CDS xseB NC_007946.1 455220 455462 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(455220..455462) Escherichia coli UTI89 3993088 YP_539478.1 CDS yajK NC_007946.1 455668 457116 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 455668..457116 Escherichia coli UTI89 3993089 YP_539479.1 CDS thiJ NC_007946.1 457170 457766 R DJ-1 family protein complement(457170..457766) Escherichia coli UTI89 3993090 YP_539480.1 CDS apbA NC_007946.1 457723 458634 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(457723..458634) Escherichia coli UTI89 3993091 YP_539481.1 CDS yajQ NC_007946.1 458634 459293 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 458634..459293 Escherichia coli UTI89 3993092 YP_539482.1 CDS yajR NC_007946.1 459421 460983 R transport protein YajR complement(459421..460983) Escherichia coli UTI89 3993093 YP_539483.1 CDS cyoE NC_007946.1 460934 461869 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(460934..461869) Escherichia coli UTI89 3993094 YP_539484.1 CDS cyoD NC_007946.1 461836 462165 R cytochrome o ubiquinol oxidase subunit IV complement(461836..462165) Escherichia coli UTI89 3993095 YP_539485.1 CDS UTI89_C0453 NC_007946.1 461858 462115 D hypothetical protein 461858..462115 Escherichia coli UTI89 3993096 YP_539486.1 CDS cyoC NC_007946.1 462165 462779 R cytochrome o ubiquinol oxidase subunit III complement(462165..462779) Escherichia coli UTI89 3993097 YP_539487.1 CDS cyoB NC_007946.1 462769 464760 R cytochrome o ubiquinol oxidase subunit I complement(462769..464760) Escherichia coli UTI89 3993098 YP_539488.1 CDS cyoA NC_007946.1 464782 465729 R cytochrome o ubiquinol oxidase subunit II complement(464782..465729) Escherichia coli UTI89 3993099 YP_539489.1 CDS ampG NC_007946.1 466188 467663 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(466188..467663) Escherichia coli UTI89 3993100 YP_539490.2 CDS yajG NC_007946.1 467707 468285 R hypothetical protein complement(467707..468285) Escherichia coli UTI89 3993101 YP_539491.1 CDS UTI89_C0459 NC_007946.1 468347 468466 R hypothetical protein complement(468347..468466) Escherichia coli UTI89 3990404 YP_539492.2 CDS bolA NC_007946.1 468590 468907 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 468590..468907 Escherichia coli UTI89 3990405 YP_539493.1 CDS UTI89_C0461 NC_007946.1 468834 469256 R hypothetical protein complement(468834..469256) Escherichia coli UTI89 3990406 YP_539494.1 CDS UTI89_C0462 NC_007946.1 468841 469104 D hypothetical protein 468841..469104 Escherichia coli UTI89 3990407 YP_539495.1 CDS tig NC_007946.1 469251 470540 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 469251..470540 Escherichia coli UTI89 3990408 YP_539496.1 CDS UTI89_C0464 NC_007946.1 469260 470561 R hypothetical protein complement(469260..470561) Escherichia coli UTI89 3990409 YP_539497.1 CDS clpP NC_007946.1 470795 471418 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 470795..471418 Escherichia coli UTI89 3990410 YP_539498.1 CDS clpX NC_007946.1 471544 472818 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 471544..472818 Escherichia coli UTI89 3990411 YP_539499.1 CDS lon NC_007946.1 472961 475360 D DNA-binding ATP-dependent protease La 472961..475360 Escherichia coli UTI89 3990412 YP_539500.1 CDS hupB NC_007946.1 475569 475841 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 475569..475841 Escherichia coli UTI89 3990413 YP_539501.1 CDS ybaU NC_007946.1 476033 477904 D peptidyl-prolyl cis-trans isomerase D 476033..477904 Escherichia coli UTI89 3990414 YP_539502.1 CDS ybaV NC_007946.1 478055 478426 D hypothetical protein 478055..478426 Escherichia coli UTI89 3990415 YP_539503.1 CDS ybaW NC_007946.1 478532 478930 D hypothetical protein 478532..478930 Escherichia coli UTI89 3990416 YP_539504.1 CDS ybaX NC_007946.1 478982 479677 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(478982..479677) Escherichia coli UTI89 3990417 YP_539505.1 CDS ybaE NC_007946.1 479742 481457 R hypothetical protein complement(479742..481457) Escherichia coli UTI89 3990418 YP_539506.1 CDS cof NC_007946.1 481530 482360 D hypothetical protein 481530..482360 Escherichia coli UTI89 3990419 YP_539507.1 CDS ybaO NC_007946.1 482405 482971 D transcriptional regulator YbaO 482405..482971 Escherichia coli UTI89 3990420 YP_539508.1 CDS mdlA NC_007946.1 483001 484773 D multidrug ABC transporter ATP-binding protein 483001..484773 Escherichia coli UTI89 3990421 YP_539509.1 CDS mdlB NC_007946.1 484652 486547 D multidrug ABC transporter ATP-binding protein 484652..486547 Escherichia coli UTI89 3990422 YP_539510.1 CDS glnK NC_007946.1 486728 487066 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 486728..487066 Escherichia coli UTI89 3990151 YP_539511.1 CDS amtB NC_007946.1 487096 488382 D ammonium transporter 487096..488382 Escherichia coli UTI89 3990152 YP_539512.1 CDS tesB NC_007946.1 488431 489375 R acyl-CoA thioesterase complement(488431..489375) Escherichia coli UTI89 3990153 YP_539513.1 CDS ybaY NC_007946.1 489509 490081 D hypothetical protein 489509..490081 Escherichia coli UTI89 3990154 YP_539514.1 CDS ybaZ NC_007946.1 490112 490522 R hypothetical protein complement(490112..490522) Escherichia coli UTI89 3990155 YP_539515.1 CDS ybaA NC_007946.1 490802 491155 D hypothetical protein 490802..491155 Escherichia coli UTI89 3990156 YP_539516.1 CDS ylaB NC_007946.1 491197 492753 R hypothetical protein complement(491197..492753) Escherichia coli UTI89 3990157 YP_539517.1 CDS ylaC NC_007946.1 492911 493420 R hypothetical protein complement(492911..493420) Escherichia coli UTI89 3990158 YP_539518.1 CDS maa NC_007946.1 493497 494048 R maltose O-acetyltransferase complement(493497..494048) Escherichia coli UTI89 3990159 YP_539519.1 CDS hha NC_007946.1 494222 494452 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(494222..494452) Escherichia coli UTI89 3990160 YP_539520.1 CDS ybaJ NC_007946.1 494466 494840 R hypothetical protein complement(494466..494840) Escherichia coli UTI89 3990161 YP_539521.1 CDS acrB NC_007946.1 495385 498534 R acridine efflux pump complement(495385..498534) Escherichia coli UTI89 3990162 YP_539522.1 CDS acrA NC_007946.1 498557 499786 R acriflavine resistance protein A complement(498557..499786) Escherichia coli UTI89 3990163 YP_539523.1 CDS acrR NC_007946.1 499892 500539 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 499892..500539 Escherichia coli UTI89 3990164 YP_539524.1 CDS kefA NC_007946.1 500667 504029 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 500667..504029 Escherichia coli UTI89 3990165 YP_539525.1 CDS ybaM NC_007946.1 504241 504402 R hypothetical protein complement(504241..504402) Escherichia coli UTI89 3990166 YP_539526.1 CDS priC NC_007946.1 504416 504943 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(504416..504943) Escherichia coli UTI89 3990167 YP_539527.1 CDS ybaN NC_007946.1 505013 505390 D hypothetical protein 505013..505390 Escherichia coli UTI89 3990168 YP_539528.1 CDS apt NC_007946.1 505489 506094 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 505489..506094 Escherichia coli UTI89 3990169 YP_539529.1 CDS dnaX NC_007946.1 506223 508154 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 506223..508154 Escherichia coli UTI89 3990170 YP_539530.1 CDS UTI89_C0498 NC_007946.1 508183 508560 R hypothetical protein complement(508183..508560) Escherichia coli UTI89 3991666 YP_539531.1 CDS ybaB NC_007946.1 508192 508536 D hypothetical protein 508192..508536 Escherichia coli UTI89 3991667 YP_539532.1 CDS recR NC_007946.1 508536 509141 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 508536..509141 Escherichia coli UTI89 3991668 YP_539533.1 CDS htpG NC_007946.1 509251 511125 D molecular chaperone; heat shock protein 90 509251..511125 Escherichia coli UTI89 3991669 YP_539534.1 CDS adk NC_007946.1 511246 511950 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 511246..511950 Escherichia coli UTI89 3991670 YP_539535.1 CDS hemH NC_007946.1 512082 513044 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 512082..513044 Escherichia coli UTI89 3991671 YP_539536.1 CDS ybaC NC_007946.1 513041 514000 R acetyl esterase complement(513041..514000) Escherichia coli UTI89 3991672 YP_539537.1 CDS gsk NC_007946.1 514152 515456 D inosine-guanosine kinase 514152..515456 Escherichia coli UTI89 3991673 YP_539538.1 CDS ybaL NC_007946.1 515586 517262 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(515586..517262) Escherichia coli UTI89 3991674 YP_539539.1 CDS fsr NC_007946.1 517501 518721 R fosmidomycin resistance protein complement(517501..518721) Escherichia coli UTI89 3991675 YP_539540.1 CDS ushA NC_007946.1 518939 520591 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase 518939..520591 Escherichia coli UTI89 3991676 YP_539541.1 CDS UTI89_C0509 NC_007946.1 520629 521132 R hypothetical protein complement(520629..521132) Escherichia coli UTI89 3991677 YP_539542.1 CDS UTI89_C0510 NC_007946.1 521129 521785 R hypothetical protein complement(521129..521785) Escherichia coli UTI89 3991678 YP_539543.1 CDS ybaK NC_007946.1 521953 522432 R hypothetical protein complement(521953..522432) Escherichia coli UTI89 3991679 YP_539544.1 CDS ybaP NC_007946.1 522636 523430 R ligase complement(522636..523430) Escherichia coli UTI89 3991680 YP_539545.1 CDS UTI89_C0513 NC_007946.1 523533 523865 D hypothetical protein 523533..523865 Escherichia coli UTI89 3991681 YP_539546.1 CDS UTI89_C0514 NC_007946.1 523901 524242 D hypothetical protein 523901..524242 Escherichia coli UTI89 3991682 YP_539547.1 CDS copA NC_007946.1 524300 526804 R copper exporting ATPase complement(524300..526804) Escherichia coli UTI89 3991683 YP_539548.1 CDS ybaS NC_007946.1 527066 527998 D catalyzes the formation of glutamate from glutamine; glutaminase 527066..527998 Escherichia coli UTI89 3991684 YP_539549.1 CDS ybaT NC_007946.1 528001 529293 D transport protein YbaT 528001..529293 Escherichia coli UTI89 3991610 YP_539550.1 CDS cueR NC_007946.1 529418 529825 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 529418..529825 Escherichia coli UTI89 3991611 YP_539551.1 CDS UTI89_C0519 NC_007946.1 529829 529996 R hypothetical protein complement(529829..529996) Escherichia coli UTI89 3991612 YP_539552.1 CDS UTI89_C0520 NC_007946.1 530029 530451 R hypothetical protein complement(530029..530451) Escherichia coli UTI89 3991613 YP_539553.1 CDS UTI89_C0521 NC_007946.1 530537 531553 R adhesin complement(530537..531553) Escherichia coli UTI89 3991614 YP_539554.1 CDS UTI89_C0522 NC_007946.1 531920 532282 D hypothetical protein 531920..532282 Escherichia coli UTI89 3991615 YP_539555.1 CDS ybbJ NC_007946.1 532385 532843 R hypothetical protein complement(532385..532843) Escherichia coli UTI89 3991616 YP_539556.1 CDS ybbK NC_007946.1 532840 533757 R protease YbbK complement(532840..533757) Escherichia coli UTI89 3991617 YP_539557.1 CDS ybbL NC_007946.1 533903 534580 D ABC transporter ATP-binding protein 533903..534580 Escherichia coli UTI89 3991618 YP_539558.1 CDS ybbM NC_007946.1 534540 535346 D metal resistance protein 534540..535346 Escherichia coli UTI89 3991619 YP_539559.1 CDS ybbN NC_007946.1 535409 536299 R thioredoxin-like protein complement(535409..536299) Escherichia coli UTI89 3991620 YP_539560.1 CDS ybbO NC_007946.1 536324 537133 R short chain dehydrogenase complement(536324..537133) Escherichia coli UTI89 3991621 YP_539561.1 CDS tesA NC_007946.1 537123 537779 R multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 complement(537123..537779) Escherichia coli UTI89 3991622 YP_539562.1 CDS ybbA NC_007946.1 537717 538403 D ABC transporter ATP-binding protein 537717..538403 Escherichia coli UTI89 3991623 YP_539563.1 CDS ybbP NC_007946.1 538400 540814 D hypothetical protein 538400..540814 Escherichia coli UTI89 3991624 YP_539564.1 CDS ybbB NC_007946.1 540873 541967 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(540873..541967) Escherichia coli UTI89 3991625 YP_539565.1 CDS ybbS NC_007946.1 542036 542962 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(542036..542962) Escherichia coli UTI89 3991626 YP_539566.1 CDS ybbT NC_007946.1 543192 543674 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 543192..543674 Escherichia coli UTI89 3991627 YP_539567.1 CDS ybbU NC_007946.1 543752 544567 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 543752..544567 Escherichia coli UTI89 3991628 YP_539568.2 CDS gcl NC_007946.1 544657 546438 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 544657..546438 Escherichia coli UTI89 3991629 YP_539569.1 CDS hyi NC_007946.1 546451 547227 D hydroxypyruvate isomerase 546451..547227 Escherichia coli UTI89 3991299 YP_539570.1 CDS ybbQ NC_007946.1 547327 548205 D 2-hydroxy-3-oxopropionate reductase 547327..548205 Escherichia coli UTI89 3991300 YP_539571.1 CDS ybbW NC_007946.1 548375 549829 D allantoin permease 548375..549829 Escherichia coli UTI89 3991301 YP_539572.1 CDS ybbX NC_007946.1 549889 551250 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 549889..551250 Escherichia coli UTI89 3991302 YP_539573.1 CDS ybbY NC_007946.1 551300 552607 D purine permease YbbY 551300..552607 Escherichia coli UTI89 3991303 YP_539574.1 CDS ybbZ NC_007946.1 552623 553774 D glycerate kinase II 552623..553774 Escherichia coli UTI89 3991304 YP_539575.1 CDS ylbA NC_007946.1 553903 554688 R hypothetical protein complement(553903..554688) Escherichia coli UTI89 3991305 YP_539576.1 CDS ylbB NC_007946.1 554699 555952 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(554699..555952) Escherichia coli UTI89 3991306 YP_539577.1 CDS allD NC_007946.1 555956 557005 R ureidoglycolate dehydrogenase complement(555956..557005) Escherichia coli UTI89 3991307 YP_539578.1 CDS fdrA NC_007946.1 557322 558989 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 557322..558989 Escherichia coli UTI89 3991308 YP_539579.1 CDS ylbE NC_007946.1 558999 560258 D hypothetical protein 558999..560258 Escherichia coli UTI89 3991309 YP_539580.1 CDS ylbF NC_007946.1 560176 561084 D hypothetical protein 560176..561084 Escherichia coli UTI89 3991310 YP_539581.1 CDS arcC NC_007946.1 561081 561974 D carbamate kinase 561081..561974 Escherichia coli UTI89 3991311 YP_539582.1 CDS purK NC_007946.1 562127 563194 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(562127..563194) Escherichia coli UTI89 3991312 YP_539583.1 CDS purE NC_007946.1 563191 563727 R phosphoribosylaminoimidazole carboxylase catalytic subunit complement(563191..563727) Escherichia coli UTI89 3991313 YP_539584.1 CDS UTI89_C0552 NC_007946.1 563796 564125 R hypothetical protein complement(563796..564125) Escherichia coli UTI89 3991314 YP_539585.1 CDS ybbF NC_007946.1 564236 564958 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(564236..564958) Escherichia coli UTI89 3991315 YP_539586.1 CDS ppiB NC_007946.1 564961 565455 R peptidyl-prolyl cis-trans isomerase B complement(564961..565455) Escherichia coli UTI89 3991316 YP_539587.1 CDS cysS NC_007946.1 565629 567014 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 565629..567014 Escherichia coli UTI89 3991317 YP_539588.1 CDS ybcI NC_007946.1 567050 567571 R hypothetical protein complement(567050..567571) Escherichia coli UTI89 3993756 YP_539589.1 CDS UTI89_C0557 NC_007946.1 567657 567914 D hypothetical protein 567657..567914 Escherichia coli UTI89 3993757 YP_539590.2 CDS ybcJ NC_007946.1 567679 567891 R hypothetical protein complement(567679..567891) Escherichia coli UTI89 3993758 YP_539591.1 CDS folD NC_007946.1 567893 568759 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(567893..568759) Escherichia coli UTI89 3993759 YP_539592.1 CDS UTI89_C0560 NC_007946.1 568809 568997 D hypothetical protein 568809..568997 Escherichia coli UTI89 3993760 YP_539593.1 CDS intD NC_007946.1 569114 569467 R prophage DLP12 integrase complement(569114..569467) Escherichia coli UTI89 3993762 YP_539594.1 CDS UTI89_C0563 NC_007946.1 569442 569834 R prophage DLP12 integrase complement(569442..569834) Escherichia coli UTI89 3993763 YP_539595.1 CDS tfaQ NC_007946.1 569748 570104 D lambdoid prophage Qin tail fiber assembly protein-like protein 569748..570104 Escherichia coli UTI89 3993764 YP_539596.1 CDS UTI89_C0565 NC_007946.1 570159 570824 R hypothetical protein complement(570159..570824) Escherichia coli UTI89 3993765 YP_539597.1 CDS ompT NC_007946.1 571059 572012 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(571059..572012) Escherichia coli UTI89 3993766 YP_539598.1 CDS ybcH NC_007946.1 572670 573560 R hypothetical protein complement(572670..573560) Escherichia coli UTI89 3993767 YP_539599.1 CDS nfrA NC_007946.1 573561 576554 R bacteriophage N4 receptor, outer membrane subunit complement(573561..576554) Escherichia coli UTI89 3993768 YP_539600.1 CDS nfrB NC_007946.1 576520 578757 R bacteriophage N4 adsorption protein B complement(576520..578757) Escherichia coli UTI89 3993769 YP_539601.1 CDS cusS NC_007946.1 578907 580349 R sensor kinase CusS complement(578907..580349) Escherichia coli UTI89 3993770 YP_539602.1 CDS ylcA NC_007946.1 580339 581022 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(580339..581022) Escherichia coli UTI89 3993771 YP_539603.1 CDS cusC NC_007946.1 581179 582561 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 581179..582561 Escherichia coli UTI89 3993772 YP_539604.1 CDS ylcC NC_007946.1 582585 582917 D periplasmic copper-binding protein 582585..582917 Escherichia coli UTI89 3993773 YP_539605.1 CDS UTI89_C0574 NC_007946.1 582933 584156 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 582933..584156 Escherichia coli UTI89 3993774 YP_539606.1 CDS cusA NC_007946.1 584168 587311 D cation efflux system protein CusA 584168..587311 Escherichia coli UTI89 3992677 YP_539607.1 CDS pheP NC_007946.1 587377 588789 D phenylalanine transporter 587377..588789 Escherichia coli UTI89 3992678 YP_539608.1 CDS ybdG NC_007946.1 588871 590118 R hypothetical protein complement(588871..590118) Escherichia coli UTI89 3992679 YP_539609.1 CDS nfnB NC_007946.1 590226 590879 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(590226..590879) Escherichia coli UTI89 3992680 YP_539610.1 CDS ybdF NC_007946.1 590958 591341 R hypothetical protein complement(590958..591341) Escherichia coli UTI89 3992681 YP_539611.1 CDS ybdJ NC_007946.1 591406 591654 R hypothetical protein complement(591406..591654) Escherichia coli UTI89 3992682 YP_539612.1 CDS ybdK NC_007946.1 591720 592838 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(591720..592838) Escherichia coli UTI89 3992683 YP_539613.1 CDS UTI89_C0582 NC_007946.1 593054 593323 R hypothetical protein complement(593054..593323) Escherichia coli UTI89 3992684 YP_539614.1 CDS entD NC_007946.1 593566 594336 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(593566..594336) Escherichia coli UTI89 3992685 YP_539615.1 CDS fepA NC_007946.1 594361 596601 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(594361..596601) Escherichia coli UTI89 3992686 YP_539616.1 CDS UTI89_C0585 NC_007946.1 596594 596725 D hypothetical protein 596594..596725 Escherichia coli UTI89 3992687 YP_539617.1 CDS fes NC_007946.1 596844 598046 D enterobactin/ferric enterobactin esterase 596844..598046 Escherichia coli UTI89 3992688 YP_539618.1 CDS UTI89_C0587 NC_007946.1 598043 598267 D hypothetical protein 598043..598267 Escherichia coli UTI89 3992689 YP_539619.1 CDS entF NC_007946.1 598264 602145 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 598264..602145 Escherichia coli UTI89 3992690 YP_539620.1 CDS fepE NC_007946.1 602361 603494 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 602361..603494 Escherichia coli UTI89 3992691 YP_539621.1 CDS fepC NC_007946.1 603491 604306 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(603491..604306) Escherichia coli UTI89 3992692 YP_539622.1 CDS fepG NC_007946.1 604303 605295 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(604303..605295) Escherichia coli UTI89 3992693 YP_539623.1 CDS fepD NC_007946.1 605292 606308 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(605292..606308) Escherichia coli UTI89 3992694 YP_539624.1 CDS ybdA NC_007946.1 606407 607657 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 606407..607657 Escherichia coli UTI89 3992695 YP_539625.1 CDS fepB NC_007946.1 607661 608617 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(607661..608617) Escherichia coli UTI89 3993178 YP_539626.1 CDS entC NC_007946.1 608794 609981 D isochorismate synthase 608794..609981 Escherichia coli UTI89 3993179 YP_539627.1 CDS entE NC_007946.1 609991 611601 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 609991..611601 Escherichia coli UTI89 3993180 YP_539628.1 CDS entB NC_007946.1 611615 612472 D 2,3-dihydro-2,3-dihydroxybenzoate synthetase 611615..612472 Escherichia coli UTI89 3993181 YP_539629.1 CDS entA NC_007946.1 612472 613218 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 612472..613218 Escherichia coli UTI89 3993182 YP_539630.1 CDS ybdB NC_007946.1 613221 613634 D hypothetical protein 613221..613634 Escherichia coli UTI89 3993183 YP_539631.1 CDS cstA NC_007946.1 613815 615920 D carbon starvation protein A 613815..615920 Escherichia coli UTI89 3993184 YP_539632.1 CDS ybdD NC_007946.1 616033 616230 D hypothetical protein 616033..616230 Escherichia coli UTI89 3993185 YP_539633.1 CDS ybdH NC_007946.1 616240 617328 R member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein complement(616240..617328) Escherichia coli UTI89 3993186 YP_539634.1 CDS ybdL NC_007946.1 617448 618608 D catalyzes the transfer of an amino moiety; aminotransferase 617448..618608 Escherichia coli UTI89 3993187 YP_539635.1 CDS ybdM NC_007946.1 618609 619238 R hypothetical protein complement(618609..619238) Escherichia coli UTI89 3993188 YP_539636.1 CDS ybdN NC_007946.1 619211 620431 R hypothetical protein complement(619211..620431) Escherichia coli UTI89 3993189 YP_539637.1 CDS ybdO NC_007946.1 620578 621516 R transcriptional regulator YbdO complement(620578..621516) Escherichia coli UTI89 3993190 YP_539638.2 CDS dsbG NC_007946.1 621685 622431 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(621685..622431) Escherichia coli UTI89 3993191 YP_539639.1 CDS ahpC NC_007946.1 622803 623366 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 622803..623366 Escherichia coli UTI89 3993192 YP_539640.1 CDS ahpF NC_007946.1 623507 625102 D alkyl hydroperoxide reductase 623507..625102 Escherichia coli UTI89 3993193 YP_539641.1 CDS uspG NC_007946.1 625223 625684 R universal stress protein UspG complement(625223..625684) Escherichia coli UTI89 3993194 YP_539642.1 CDS UTI89_C0611 NC_007946.1 625935 626318 D hypothetical protein 625935..626318 Escherichia coli UTI89 3993195 YP_539643.1 CDS rnk NC_007946.1 626007 626417 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(626007..626417) Escherichia coli UTI89 3993196 YP_539644.1 CDS rna NC_007946.1 626647 627471 R ribonuclease I complement(626647..627471) Escherichia coli UTI89 3993197 YP_539645.1 CDS citT NC_007946.1 627567 629030 R citrate DASS carrier/transporter complement(627567..629030) Escherichia coli UTI89 3990938 YP_539646.1 CDS citG NC_007946.1 629081 629959 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(629081..629959) Escherichia coli UTI89 3990939 YP_539647.1 CDS citX NC_007946.1 629934 630485 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase complement(629934..630485) Escherichia coli UTI89 3990940 YP_539648.1 CDS UTI89_C0617 NC_007946.1 630453 631847 D hypothetical protein 630453..631847 Escherichia coli UTI89 3990941 YP_539649.1 CDS citF NC_007946.1 630489 632021 R citrate lyase subunit alpha complement(630489..632021) Escherichia coli UTI89 3990942 YP_539650.1 CDS UTI89_C0619 NC_007946.1 632023 633069 D hypothetical protein 632023..633069 Escherichia coli UTI89 3990943 YP_539651.1 CDS citE NC_007946.1 632032 632955 R citrate lyase subunit beta complement(632032..632955) Escherichia coli UTI89 3990944 YP_539652.1 CDS citD NC_007946.1 632937 633233 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(632937..633233) Escherichia coli UTI89 3990945 YP_539653.1 CDS citC NC_007946.1 633248 634393 R citrate lyase synthetase complement(633248..634393) Escherichia coli UTI89 3990946 YP_539654.1 CDS dpiB NC_007946.1 634625 636343 D sensor kinase DpiB 634625..636343 Escherichia coli UTI89 3990947 YP_539655.1 CDS dpiA NC_007946.1 636312 636992 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 636312..636992 Escherichia coli UTI89 3990948 YP_539656.1 CDS dcuC NC_007946.1 637033 638418 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(637033..638418) Escherichia coli UTI89 3990949 YP_539657.1 CDS pagP NC_007946.1 639005 639565 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 639005..639565 Escherichia coli UTI89 3990950 YP_539658.1 CDS cspE NC_007946.1 639656 639949 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 639656..639949 Escherichia coli UTI89 3990951 YP_539659.1 CDS crcB NC_007946.1 640003 640386 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(640003..640386) Escherichia coli UTI89 3990952 YP_539660.1 CDS ybeM NC_007946.1 640476 641270 D amidase 640476..641270 Escherichia coli UTI89 3990953 YP_539661.1 CDS tatE NC_007946.1 641399 641602 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 641399..641602 Escherichia coli UTI89 3990954 YP_539662.1 CDS lipA NC_007946.1 641702 642667 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(641702..642667) Escherichia coli UTI89 3990955 YP_539663.1 CDS lipB NC_007946.1 643487 644128 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(643487..644128) Escherichia coli UTI89 3990956 YP_539664.1 CDS ybeD NC_007946.1 644229 644492 R hypothetical protein complement(644229..644492) Escherichia coli UTI89 3989723 YP_539665.1 CDS dacA NC_007946.1 644602 645813 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A complement(644602..645813) Escherichia coli UTI89 3989724 YP_539666.1 CDS rlpA NC_007946.1 645953 647041 R rare lipoprotein A complement(645953..647041) Escherichia coli UTI89 3989725 YP_539667.1 CDS mrdB NC_007946.1 647052 648164 R cell wall shape-determining protein complement(647052..648164) Escherichia coli UTI89 3989726 YP_539668.1 CDS mrdA NC_007946.1 648167 650068 R penicillin-binding protein 2 complement(648167..650068) Escherichia coli UTI89 3989727 YP_539669.1 CDS ybeA NC_007946.1 650099 650566 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(650099..650566) Escherichia coli UTI89 3989728 YP_539670.1 CDS ybeB NC_007946.1 650570 650887 R hypothetical protein complement(650570..650887) Escherichia coli UTI89 3989729 YP_539671.1 CDS UTI89_C0640 NC_007946.1 650901 651191 D hypothetical protein 650901..651191 Escherichia coli UTI89 3989730 YP_539672.1 CDS phpB NC_007946.1 651147 651761 R alpha-ribazole-5'-phosphate phosphatase complement(651147..651761) Escherichia coli UTI89 3989731 YP_539673.1 CDS nadD NC_007946.1 651782 652486 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(651782..652486) Escherichia coli UTI89 3989732 YP_539674.1 CDS holA NC_007946.1 652425 653456 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(652425..653456) Escherichia coli UTI89 3989733 YP_539675.1 CDS rlpB NC_007946.1 653456 654037 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(653456..654037) Escherichia coli UTI89 3989734 YP_539676.1 CDS leuS NC_007946.1 654052 656775 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(654052..656775) Escherichia coli UTI89 3989735 YP_539677.1 CDS ybeL NC_007946.1 656869 657351 D hypothetical protein 656869..657351 Escherichia coli UTI89 3989736 YP_539678.2 CDS rihA NC_007946.1 657396 658331 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(657396..658331) Escherichia coli UTI89 3989737 YP_539679.1 CDS gltL NC_007946.1 658449 659174 R ATP-binding protein of glutamate/aspartate transport system complement(658449..659174) Escherichia coli UTI89 3989738 YP_539680.1 CDS gltK NC_007946.1 659174 659848 R glutamate/aspartate transport system permease complement(659174..659848) Escherichia coli UTI89 3989739 YP_539681.1 CDS gltJ NC_007946.1 659848 660588 R glutamate ABC transporter complement(659848..660588) Escherichia coli UTI89 3989740 YP_539682.1 CDS ybeJ NC_007946.1 660758 661735 R glutamate and aspartate transporter subunit complement(660758..661735) Escherichia coli UTI89 3989741 YP_539683.1 CDS UTI89_C0652 NC_007946.1 661801 661923 D hypothetical protein 661801..661923 Escherichia coli UTI89 3989742 YP_539684.1 CDS UTI89_C0653 NC_007946.1 662120 663997 D hypothetical protein 662120..663997 Escherichia coli UTI89 3991388 YP_539685.1 CDS UTI89_C0654 NC_007946.1 663966 664142 D hypothetical protein 663966..664142 Escherichia coli UTI89 3991389 YP_539686.1 CDS lnt NC_007946.1 664124 665665 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(664124..665665) Escherichia coli UTI89 3991390 YP_539687.1 CDS ybeX NC_007946.1 665690 666568 R transport protein complement(665690..666568) Escherichia coli UTI89 3991391 YP_539688.1 CDS ybeY NC_007946.1 666658 667125 R metalloprotease complement(666658..667125) Escherichia coli UTI89 3991392 YP_539689.1 CDS ybeZ NC_007946.1 667122 668201 R ATP-binding protein in pho regulon complement(667122..668201) Escherichia coli UTI89 3991393 YP_539690.1 CDS UTI89_C0659 NC_007946.1 668315 669739 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(668315..669739) Escherichia coli UTI89 3991394 YP_539691.1 CDS ubiF NC_007946.1 669885 671060 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 669885..671060 Escherichia coli UTI89 3991395 YP_539692.1 CDS asnB NC_007946.1 672301 674199 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(672301..674199) Escherichia coli UTI89 3990331 YP_539693.1 CDS nagD NC_007946.1 674221 674973 R UMP phosphatase complement(674221..674973) Escherichia coli UTI89 3990332 YP_539694.1 CDS nagC NC_007946.1 675021 676241 R N-acetylglucosamine operon transcriptional repressor complement(675021..676241) Escherichia coli UTI89 3990333 YP_539695.1 CDS nagA NC_007946.1 676250 677398 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(676250..677398) Escherichia coli UTI89 3990334 YP_539696.1 CDS nagB NC_007946.1 677458 678258 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(677458..678258) Escherichia coli UTI89 3990335 YP_539697.1 CDS UTI89_C0673 NC_007946.1 678307 678441 R hypothetical protein complement(678307..678441) Escherichia coli UTI89 3990336 YP_539698.1 CDS nagE NC_007946.1 678591 680537 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 678591..680537 Escherichia coli UTI89 3990337 YP_539699.1 CDS UTI89_C0675 NC_007946.1 680507 680659 R hypothetical protein complement(680507..680659) Escherichia coli UTI89 3990338 YP_539700.1 CDS UTI89_C0676 NC_007946.1 680626 681906 R hypothetical protein complement(680626..681906) Escherichia coli UTI89 3990339 YP_539701.1 CDS UTI89_C0677 NC_007946.1 681920 682390 R hypothetical protein complement(681920..682390) Escherichia coli UTI89 3990340 YP_539702.1 CDS UTI89_C0678 NC_007946.1 682387 683556 R hypothetical protein complement(682387..683556) Escherichia coli UTI89 3990341 YP_539703.1 CDS UTI89_C0679 NC_007946.1 684402 685289 R dihydrodipicolinate synthase complement(684402..685289) Escherichia coli UTI89 3990342 YP_539704.1 CDS UTI89_C0680 NC_007946.1 685293 686450 R alcohol dehydrogenase complement(685293..686450) Escherichia coli UTI89 3990343 YP_539705.1 CDS UTI89_C0681 NC_007946.1 686725 687855 D hypothetical protein 686725..687855 Escherichia coli UTI89 3990344 YP_539706.1 CDS pdxA NC_007946.1 687848 688834 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 687848..688834 Escherichia coli UTI89 3990345 YP_539707.1 CDS UTI89_C0683 NC_007946.1 688836 689597 D transcriptional regulator 688836..689597 Escherichia coli UTI89 3990346 YP_539708.1 CDS glnS NC_007946.1 689817 691481 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 689817..691481 Escherichia coli UTI89 3994292 YP_539709.1 CDS ybfM NC_007946.1 691930 693336 D hypothetical protein 691930..693336 Escherichia coli UTI89 3994293 YP_539710.1 CDS ybfN NC_007946.1 693386 693712 D lipoprotein YbfN 693386..693712 Escherichia coli UTI89 3994294 YP_539711.1 CDS fur NC_007946.1 693796 694242 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(693796..694242) Escherichia coli UTI89 3994295 YP_539712.1 CDS ybfJ NC_007946.1 694287 694541 D hypothetical protein 694287..694541 Escherichia coli UTI89 3994296 YP_539713.1 CDS fldA NC_007946.1 694531 695178 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(694531..695178) Escherichia coli UTI89 3994297 YP_539714.1 CDS ybfE NC_007946.1 695201 695563 R LexA regulated protein complement(695201..695563) Escherichia coli UTI89 3994298 YP_539715.1 CDS ybfF NC_007946.1 695634 696398 R hypothetical protein complement(695634..696398) Escherichia coli UTI89 3994299 YP_539716.2 CDS seqA NC_007946.1 696583 697128 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 696583..697128 Escherichia coli UTI89 3994300 YP_539717.1 CDS pgm NC_007946.1 697103 698794 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 697103..698794 Escherichia coli UTI89 3994301 YP_539718.1 CDS potE NC_007946.1 698851 700170 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(698851..700170) Escherichia coli UTI89 3994302 YP_539719.1 CDS speF NC_007946.1 700167 702374 R ornithine decarboxylase complement(700167..702374) Escherichia coli UTI89 3994303 YP_539720.1 CDS UTI89_C0696 NC_007946.1 702379 702531 R hypothetical protein complement(702379..702531) Escherichia coli UTI89 3994304 YP_539721.1 CDS UTI89_C0697 NC_007946.1 702898 703032 D hypothetical protein 702898..703032 Escherichia coli UTI89 3994305 YP_539722.1 CDS kdpE NC_007946.1 703054 703731 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(703054..703731) Escherichia coli UTI89 3994306 YP_539723.1 CDS kdpD NC_007946.1 703728 706415 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(703728..706415) Escherichia coli UTI89 3994307 YP_539724.1 CDS kdpC NC_007946.1 706405 707001 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(706405..707001) Escherichia coli UTI89 3994308 YP_539725.1 CDS kdpB NC_007946.1 706986 709034 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(706986..709034) Escherichia coli UTI89 3994309 YP_539726.1 CDS kdpA NC_007946.1 709057 710730 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(709057..710730) Escherichia coli UTI89 3994310 YP_539727.1 CDS UTI89_C0703 NC_007946.1 710730 710933 R hypothetical protein complement(710730..710933) Escherichia coli UTI89 3994311 YP_539728.1 CDS ybfA NC_007946.1 711132 711338 D hypothetical protein 711132..711338 Escherichia coli UTI89 3993966 YP_539729.1 CDS ybgA NC_007946.1 711439 711948 D hypothetical protein 711439..711948 Escherichia coli UTI89 3993967 YP_539730.1 CDS phrB NC_007946.1 711945 713363 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 711945..713363 Escherichia coli UTI89 3993968 YP_539731.1 CDS ybgH NC_007946.1 713405 714886 R transporter YbgH complement(713405..714886) Escherichia coli UTI89 3993969 YP_539732.1 CDS ybgI NC_007946.1 715157 715900 D hydrolase-oxidase 715157..715900 Escherichia coli UTI89 3993970 YP_539733.1 CDS ybgJ NC_007946.1 715923 716579 D hypothetical protein 715923..716579 Escherichia coli UTI89 3993971 YP_539734.1 CDS ybgK NC_007946.1 716573 717505 D hypothetical protein 716573..717505 Escherichia coli UTI89 3993972 YP_539735.1 CDS ybgL NC_007946.1 717495 718229 D LamB/YcsF family protein 717495..718229 Escherichia coli UTI89 3993973 YP_539736.1 CDS nei NC_007946.1 718265 719056 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 718265..719056 Escherichia coli UTI89 3993974 YP_539737.1 CDS abrB NC_007946.1 719053 720144 R transport protein AbrB complement(719053..720144) Escherichia coli UTI89 3993975 YP_539738.1 CDS ybgO NC_007946.1 720251 720625 R hypothetical protein complement(720251..720625) Escherichia coli UTI89 3993976 YP_539739.1 CDS gltA NC_007946.1 720773 722056 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(720773..722056) Escherichia coli UTI89 3993977 YP_539740.1 CDS UTI89_C0716 NC_007946.1 722038 722229 D hypothetical protein 722038..722229 Escherichia coli UTI89 3993978 YP_539741.1 CDS sdhC NC_007946.1 722750 723154 D succinate dehydrogenase cytochrome b556 large membrane subunit 722750..723154 Escherichia coli UTI89 3993979 YP_539742.1 CDS sdhD NC_007946.1 723148 723495 D succinate dehydrogenase cytochrome b556 small membrane subunit 723148..723495 Escherichia coli UTI89 3993980 YP_539743.1 CDS sdhA NC_007946.1 723483 725261 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 723483..725261 Escherichia coli UTI89 3993981 YP_539744.1 CDS sdhB NC_007946.1 725277 725993 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 725277..725993 Escherichia coli UTI89 3993982 YP_539745.1 CDS sucA NC_007946.1 726354 729155 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 726354..729155 Escherichia coli UTI89 3993983 YP_539746.1 CDS sucB NC_007946.1 729170 730387 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 729170..730387 Escherichia coli UTI89 3993984 YP_539747.1 CDS sucC NC_007946.1 730481 731647 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 730481..731647 Escherichia coli UTI89 3993463 YP_539748.1 CDS sucD NC_007946.1 731647 732516 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 731647..732516 Escherichia coli UTI89 3993464 YP_539749.1 CDS UTI89_C0725 NC_007946.1 732756 733871 D hypothetical protein 732756..733871 Escherichia coli UTI89 3993465 YP_539750.1 CDS UTI89_C0726 NC_007946.1 733753 734097 D hypothetical protein 733753..734097 Escherichia coli UTI89 3993466 YP_539751.1 CDS cydA NC_007946.1 735198 736769 D cytochrome d terminal oxidase, polypeptide subunit I 735198..736769 Escherichia coli UTI89 3993467 YP_539752.1 CDS UTI89_C0728 NC_007946.1 736674 737954 R hypothetical protein complement(736674..737954) Escherichia coli UTI89 3993468 YP_539753.1 CDS cydB NC_007946.1 736785 737924 D cytochrome d terminal oxidase polypeptide subunit II 736785..737924 Escherichia coli UTI89 3993469 YP_539754.1 CDS UTI89_C0730 NC_007946.1 737939 738052 D hypothetical protein 737939..738052 Escherichia coli UTI89 3993470 YP_539755.1 CDS ybgE NC_007946.1 738052 738345 D hypothetical protein 738052..738345 Escherichia coli UTI89 3993471 YP_539756.1 CDS ybgC NC_007946.1 738495 738899 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 738495..738899 Escherichia coli UTI89 3993472 YP_539757.1 CDS tolQ NC_007946.1 738896 739588 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 738896..739588 Escherichia coli UTI89 3993473 YP_539758.1 CDS tolR NC_007946.1 739592 740020 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 739592..740020 Escherichia coli UTI89 3993474 YP_539759.1 CDS tolA NC_007946.1 740085 741335 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 740085..741335 Escherichia coli UTI89 3993475 YP_539760.1 CDS tolB NC_007946.1 741465 742760 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 741465..742760 Escherichia coli UTI89 3993476 YP_539761.1 CDS UTI89_C0737 NC_007946.1 742729 743346 R hypothetical protein complement(742729..743346) Escherichia coli UTI89 3993477 YP_539762.1 CDS pal NC_007946.1 742771 743316 D peptidoglycan-associated outer membrane lipoprotein 742771..743316 Escherichia coli UTI89 3993478 YP_539763.1 CDS ybgF NC_007946.1 743326 744117 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 743326..744117 Escherichia coli UTI89 3993479 YP_539764.1 CDS nadA NC_007946.1 745263 746306 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 745263..746306 Escherichia coli UTI89 3991524 YP_539765.1 CDS pnuC NC_007946.1 746344 747063 D PnuC NMN transporter 746344..747063 Escherichia coli UTI89 3991525 YP_539766.1 CDS UTI89_C0749 NC_007946.1 747060 748001 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(747060..748001) Escherichia coli UTI89 3991526 YP_539767.1 CDS UTI89_C0750 NC_007946.1 748115 748495 R homeobox protein complement(748115..748495) Escherichia coli UTI89 3991527 YP_539768.1 CDS aroG NC_007946.1 748811 749863 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 748811..749863 Escherichia coli UTI89 3991528 YP_539769.1 CDS gpmA NC_007946.1 750030 750797 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(750030..750797) Escherichia coli UTI89 3991529 YP_539770.1 CDS galM NC_007946.1 750985 752025 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(750985..752025) Escherichia coli UTI89 3991530 YP_539771.1 CDS galK NC_007946.1 752019 753167 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(752019..753167) Escherichia coli UTI89 3991531 YP_539772.1 CDS galT NC_007946.1 753171 754217 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(753171..754217) Escherichia coli UTI89 3992873 YP_539773.1 CDS UTI89_C0756 NC_007946.1 754227 755243 R UDP-galactose-4-epimerase complement(754227..755243) Escherichia coli UTI89 3992874 YP_539774.2 CDS modF NC_007946.1 755506 756978 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(755506..756978) Escherichia coli UTI89 3992875 YP_539775.1 CDS modE NC_007946.1 757046 757834 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; ModE family transcriptional regulator complement(757046..757834) Escherichia coli UTI89 3992876 YP_539776.1 CDS ybhT NC_007946.1 757957 758112 D hypothetical protein 757957..758112 Escherichia coli UTI89 3992877 YP_539777.1 CDS UTI89_C0760 NC_007946.1 758048 758257 D hypothetical protein 758048..758257 Escherichia coli UTI89 3992878 YP_539778.1 CDS modA NC_007946.1 758279 759052 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 758279..759052 Escherichia coli UTI89 3992879 YP_539779.1 CDS modB NC_007946.1 759052 759741 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 759052..759741 Escherichia coli UTI89 3992880 YP_539780.1 CDS modC NC_007946.1 759744 760802 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate ABC transporter ATP-binding protein 759744..760802 Escherichia coli UTI89 3992881 YP_539781.1 CDS ybhA NC_007946.1 760803 761621 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(760803..761621) Escherichia coli UTI89 3992882 YP_539782.1 CDS ybhE NC_007946.1 761776 762771 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 761776..762771 Escherichia coli UTI89 3992883 YP_539783.1 CDS ybhD NC_007946.1 762812 763828 R transcriptional regulator YbhD complement(762812..763828) Escherichia coli UTI89 3992884 YP_539784.1 CDS ybhH NC_007946.1 763949 765001 D hypothetical protein 763949..765001 Escherichia coli UTI89 3992885 YP_539785.1 CDS ybhI NC_007946.1 765077 766510 D hypothetical protein 765077..766510 Escherichia coli UTI89 3992886 YP_539786.2 CDS ybhJ NC_007946.1 766693 768954 D hypothetical protein 766693..768954 Escherichia coli UTI89 3992887 YP_539787.1 CDS ybhC NC_007946.1 769095 770378 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase complement(769095..770378) Escherichia coli UTI89 3992888 YP_539788.1 CDS ybhB NC_007946.1 770530 771006 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(770530..771006) Escherichia coli UTI89 3992889 YP_539789.1 CDS bioA NC_007946.1 771065 772465 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(771065..772465) Escherichia coli UTI89 3992890 YP_539790.1 CDS bioB NC_007946.1 772441 773481 D biotin synthase 772441..773481 Escherichia coli UTI89 3992891 YP_539791.1 CDS bioF NC_007946.1 773478 774632 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 773478..774632 Escherichia coli UTI89 3993848 YP_539792.1 CDS bioC NC_007946.1 774580 775374 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 774580..775374 Escherichia coli UTI89 3993849 YP_539793.1 CDS bioD NC_007946.1 775367 776044 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 775367..776044 Escherichia coli UTI89 3993850 YP_539794.1 CDS uvrB NC_007946.1 776623 778644 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 776623..778644 Escherichia coli UTI89 3993851 YP_539795.1 CDS ybhK NC_007946.1 778682 779650 R hypothetical protein complement(778682..779650) Escherichia coli UTI89 3993852 YP_539796.1 CDS UTI89_C0779 NC_007946.1 779833 779988 R hypothetical protein complement(779833..779988) Escherichia coli UTI89 3993853 YP_539797.1 CDS moaA NC_007946.1 779906 780976 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 779906..780976 Escherichia coli UTI89 3993854 YP_539798.1 CDS moaB NC_007946.1 780998 781510 D molybdopterin biosynthesis, protein B 780998..781510 Escherichia coli UTI89 3993855 YP_539799.1 CDS UTI89_C0782 NC_007946.1 781252 781743 R hypothetical protein complement(781252..781743) Escherichia coli UTI89 3993856 YP_539800.1 CDS moaC NC_007946.1 781513 781998 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 781513..781998 Escherichia coli UTI89 3993857 YP_539801.2 CDS moaD NC_007946.1 781991 782236 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 781991..782236 Escherichia coli UTI89 3993858 YP_539802.1 CDS moaE NC_007946.1 782238 782690 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 782238..782690 Escherichia coli UTI89 3993859 YP_539803.1 CDS ybhL NC_007946.1 782827 783531 D hypothetical protein 782827..783531 Escherichia coli UTI89 3993860 YP_539804.1 CDS UTI89_C0787 NC_007946.1 783463 783594 R hypothetical protein complement(783463..783594) Escherichia coli UTI89 3993861 YP_539805.1 CDS ybhM NC_007946.1 783710 784450 D hypothetical protein 783710..784450 Escherichia coli UTI89 3993862 YP_539806.1 CDS ybhN NC_007946.1 784486 785442 R hypothetical protein complement(784486..785442) Escherichia coli UTI89 3993863 YP_539807.1 CDS ybhO NC_007946.1 785442 786683 R cardiolipin synthase 2 complement(785442..786683) Escherichia coli UTI89 3993864 YP_539808.1 CDS ybhP NC_007946.1 786680 787441 R DNase complement(786680..787441) Escherichia coli UTI89 3993865 YP_539809.1 CDS ybhQ NC_007946.1 787574 787984 D hypothetical protein 787574..787984 Escherichia coli UTI89 3993866 YP_539810.1 CDS ybhR NC_007946.1 787946 789052 R hypothetical protein complement(787946..789052) Escherichia coli UTI89 3993867 YP_539811.1 CDS ybhS NC_007946.1 789063 790196 R hypothetical protein complement(789063..790196) Escherichia coli UTI89 3994481 YP_539812.1 CDS ybhF NC_007946.1 790189 791940 R ABC transporter complement(790189..791940) Escherichia coli UTI89 3994482 YP_539813.1 CDS ybhG NC_007946.1 791918 792916 R hypothetical protein complement(791918..792916) Escherichia coli UTI89 3994483 YP_539814.1 CDS ybiH NC_007946.1 792916 793599 R DNA-binding transcriptional regulator complement(792916..793599) Escherichia coli UTI89 3994484 YP_539815.1 CDS rhlE NC_007946.1 793816 795177 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 793816..795177 Escherichia coli UTI89 3994485 YP_539818.1 CDS UTI89_C0801 NC_007946.1 795410 795715 R hypothetical protein complement(795410..795715) Escherichia coli UTI89 3994488 YP_539819.1 CDS dinG NC_007946.1 795714 797864 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 795714..797864 Escherichia coli UTI89 3994489 YP_539820.1 CDS ybiB NC_007946.1 797892 798854 D glycosyl transferase 797892..798854 Escherichia coli UTI89 3994490 YP_539821.1 CDS ybiC NC_007946.1 798995 800080 D hypothetical protein 798995..800080 Escherichia coli UTI89 3994491 YP_539822.1 CDS ybiJ NC_007946.1 800308 800568 R hypothetical protein complement(800308..800568) Escherichia coli UTI89 3994492 YP_539823.1 CDS UTI89_C0806 NC_007946.1 800833 801099 R hypothetical protein complement(800833..801099) Escherichia coli UTI89 3994493 YP_539824.1 CDS ybiX NC_007946.1 801173 801886 R hydroxylase complement(801173..801886) Escherichia coli UTI89 3994494 YP_539825.1 CDS ybiL NC_007946.1 802066 804348 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(802066..804348) Escherichia coli UTI89 3994495 YP_539826.1 CDS ybiM NC_007946.1 804613 805017 R hypothetical protein complement(804613..805017) Escherichia coli UTI89 3994496 YP_539827.1 CDS ybiN NC_007946.1 805059 806075 D SAM-dependent methyltransferase 805059..806075 Escherichia coli UTI89 3994497 YP_539828.2 CDS ybiO NC_007946.1 806072 808297 R hypothetical protein complement(806072..808297) Escherichia coli UTI89 3994498 YP_539829.1 CDS glnQ NC_007946.1 808414 809136 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(808414..809136) Escherichia coli UTI89 3994499 YP_539830.1 CDS glnP NC_007946.1 809133 809792 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(809133..809792) Escherichia coli UTI89 3992638 YP_539831.1 CDS glnH NC_007946.1 809931 810677 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter substrate-binding protein complement(809931..810677) Escherichia coli UTI89 3992639 YP_539832.1 CDS UTI89_C0815 NC_007946.1 810723 811016 R hypothetical protein complement(810723..811016) Escherichia coli UTI89 3992640 YP_539833.1 CDS dps NC_007946.1 811081 811677 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(811081..811677) Escherichia coli UTI89 3992641 YP_539834.1 CDS ybiF NC_007946.1 811883 812782 R threonine and homoserine efflux system complement(811883..812782) Escherichia coli UTI89 3992642 YP_539835.1 CDS ompX NC_007946.1 813117 813638 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 813117..813638 Escherichia coli UTI89 3992643 YP_539836.1 CDS ybiP NC_007946.1 813688 815271 R hypothetical protein complement(813688..815271) Escherichia coli UTI89 3992644 YP_539837.1 CDS UTI89_C0820 NC_007946.1 815543 815671 R hypothetical protein complement(815543..815671) Escherichia coli UTI89 3992645 YP_539838.1 CDS mntR NC_007946.1 815857 816324 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 815857..816324 Escherichia coli UTI89 3992646 YP_539839.1 CDS ybiR NC_007946.1 816321 817439 D hypothetical protein 816321..817439 Escherichia coli UTI89 3992647 YP_539840.1 CDS ybiS NC_007946.1 817497 818417 R hypothetical protein complement(817497..818417) Escherichia coli UTI89 3992648 YP_539841.1 CDS ybiT NC_007946.1 818636 820228 D ABC transporter ATP-binding protein 818636..820228 Escherichia coli UTI89 3992649 YP_539842.1 CDS ybiV NC_007946.1 820428 821243 R hypothetical protein complement(820428..821243) Escherichia coli UTI89 3992650 YP_539843.1 CDS ybiW NC_007946.1 821389 823821 R formate acetyltransferase 3 complement(821389..823821) Escherichia coli UTI89 3992651 YP_539844.1 CDS UTI89_C0827 NC_007946.1 823827 824753 R pyruvate formate-lyase 3 activating enzyme complement(823827..824753) Escherichia coli UTI89 3992652 YP_539845.2 CDS UTI89_C0828 NC_007946.1 824857 825519 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 824857..825519 Escherichia coli UTI89 3992653 YP_539846.1 CDS moeB NC_007946.1 825595 826344 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(825595..826344) Escherichia coli UTI89 3992654 YP_539847.1 CDS moeA NC_007946.1 826344 827579 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(826344..827579) Escherichia coli UTI89 3992655 YP_539848.1 CDS ybiK NC_007946.1 827783 828748 D L-asparaginase 827783..828748 Escherichia coli UTI89 3992656 YP_539849.1 CDS UTI89_C0832 NC_007946.1 828627 830606 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 828627..830606 Escherichia coli UTI89 3992657 YP_539850.1 CDS UTI89_C0833 NC_007946.1 830368 832164 D hemin-binding lipoprotein 830368..832164 Escherichia coli UTI89 3993139 YP_539851.1 CDS yliC NC_007946.1 832182 833102 D ABC transporter permease 832182..833102 Escherichia coli UTI89 3993140 YP_539852.1 CDS UTI89_C0835 NC_007946.1 833105 834016 D transport system permease 833105..834016 Escherichia coli UTI89 3993141 YP_539853.1 CDS yliE NC_007946.1 834193 836541 D hypothetical protein 834193..836541 Escherichia coli UTI89 3993142 YP_539854.1 CDS yliF NC_007946.1 836549 837877 D hypothetical protein 836549..837877 Escherichia coli UTI89 3993143 YP_539855.1 CDS rimO NC_007946.1 837924 839249 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(837924..839249) Escherichia coli UTI89 3993144 YP_539856.2 CDS bssR NC_007946.1 839462 839845 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 839462..839845 Escherichia coli UTI89 3993145 YP_539857.1 CDS yliI NC_007946.1 839956 841071 D hypothetical protein 839956..841071 Escherichia coli UTI89 3993146 YP_539858.1 CDS yliJ NC_007946.1 841068 841700 R GST-like protein complement(841068..841700) Escherichia coli UTI89 3993147 YP_539859.1 CDS dacC NC_007946.1 841920 843143 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 841920..843143 Escherichia coli UTI89 3993148 YP_539860.1 CDS deoR NC_007946.1 843190 843948 R DNA-binding transcriptional repressor DeoR complement(843190..843948) Escherichia coli UTI89 3993149 YP_539861.1 CDS ybjG NC_007946.1 844006 844602 R undecaprenyl pyrophosphate phosphatase complement(844006..844602) Escherichia coli UTI89 3993150 YP_539862.1 CDS cmr NC_007946.1 844857 846119 D MdfA/Cmr MFS multidrug transporter 844857..846119 Escherichia coli UTI89 3993151 YP_539863.1 CDS ybjH NC_007946.1 846160 846426 R hypothetical protein complement(846160..846426) Escherichia coli UTI89 3993152 YP_539864.1 CDS ybjI NC_007946.1 846511 847329 R hypothetical protein complement(846511..847329) Escherichia coli UTI89 3993153 YP_539865.1 CDS ybjJ NC_007946.1 847326 848597 R DEOR-type transcriptional regulator complement(847326..848597) Escherichia coli UTI89 3993154 YP_539866.1 CDS ybjK NC_007946.1 848588 849154 D DEOR-type transcriptional regulator 848588..849154 Escherichia coli UTI89 3993155 YP_539867.1 CDS ybjL NC_007946.1 849329 851014 R hypothetical protein complement(849329..851014) Escherichia coli UTI89 3993156 YP_539868.1 CDS ybjM NC_007946.1 851284 851661 D hypothetical protein 851284..851661 Escherichia coli UTI89 3993157 YP_539869.2 CDS grxA NC_007946.1 851691 851948 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 complement(851691..851948) Escherichia coli UTI89 3993659 YP_539870.1 CDS ybjC NC_007946.1 852108 852395 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 852108..852395 Escherichia coli UTI89 3993660 YP_539871.1 CDS nfsA NC_007946.1 852379 853101 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 852379..853101 Escherichia coli UTI89 3993661 YP_539872.1 CDS rimK NC_007946.1 853162 854064 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 853162..854064 Escherichia coli UTI89 3993662 YP_539873.1 CDS ybjN NC_007946.1 854104 854628 D sensory transduction regulator 854104..854628 Escherichia coli UTI89 3993663 YP_539874.1 CDS potF NC_007946.1 854834 856090 D putrescine ABC transporter substrate-binding protein 854834..856090 Escherichia coli UTI89 3993664 YP_539875.2 CDS potG NC_007946.1 856185 857318 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding protein 856185..857318 Escherichia coli UTI89 3993665 YP_539876.1 CDS potH NC_007946.1 857328 858281 D putrescine ABC transporter 857328..858281 Escherichia coli UTI89 3993666 YP_539877.1 CDS potI NC_007946.1 858236 859123 D putrescine ABC transporter 858236..859123 Escherichia coli UTI89 3993667 YP_539878.1 CDS ybjO NC_007946.1 859183 859671 D hypothetical protein 859183..859671 Escherichia coli UTI89 3993668 YP_539879.1 CDS rumB NC_007946.1 859712 860839 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 859712..860839 Escherichia coli UTI89 3993669 YP_539880.1 CDS artJ NC_007946.1 860868 861650 R arginine-binding periplasmic protein 2 complement(860868..861650) Escherichia coli UTI89 3993670 YP_539881.1 CDS artM NC_007946.1 861825 862493 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(861825..862493) Escherichia coli UTI89 3993671 YP_539882.1 CDS artQ NC_007946.1 862493 863209 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(862493..863209) Escherichia coli UTI89 3993672 YP_539883.1 CDS artI NC_007946.1 863216 863947 R arginine-binding periplasmic protein 1 complement(863216..863947) Escherichia coli UTI89 3993673 YP_539884.2 CDS artP NC_007946.1 863965 864693 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(863965..864693) Escherichia coli UTI89 3993674 YP_539885.1 CDS ybjP NC_007946.1 864911 865450 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(864911..865450) Escherichia coli UTI89 3993675 YP_539886.1 CDS ybjQ NC_007946.1 865552 865875 D hypothetical protein 865552..865875 Escherichia coli UTI89 3993676 YP_539887.1 CDS ybjR NC_007946.1 865872 866702 D N-acetylmuramoyl-L-alanine amidase 865872..866702 Escherichia coli UTI89 3993677 YP_539888.1 CDS ybjS NC_007946.1 866699 867775 R hypothetical protein complement(866699..867775) Escherichia coli UTI89 3993678 YP_539889.1 CDS ybjT NC_007946.1 867811 869316 R hypothetical protein complement(867811..869316) Escherichia coli UTI89 3993102 YP_539890.1 CDS ybjU NC_007946.1 869252 870253 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(869252..870253) Escherichia coli UTI89 3993103 YP_539891.1 CDS poxB NC_007946.1 870290 872008 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(870290..872008) Escherichia coli UTI89 3993104 YP_539892.1 CDS hcr NC_007946.1 872141 873115 R HCP oxidoreductase, NADH-dependent complement(872141..873115) Escherichia coli UTI89 3993105 YP_539893.1 CDS ybjW NC_007946.1 873121 874779 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(873121..874779) Escherichia coli UTI89 3993106 YP_539894.1 CDS ybjE NC_007946.1 874917 875816 R hypothetical protein complement(874917..875816) Escherichia coli UTI89 3993107 YP_539895.1 CDS aqpZ NC_007946.1 876137 876838 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(876137..876838) Escherichia coli UTI89 3993108 YP_539896.1 CDS UTI89_C0879 NC_007946.1 877045 877200 R hypothetical protein complement(877045..877200) Escherichia coli UTI89 3993109 YP_539897.1 CDS ybjD NC_007946.1 877258 878916 D hypothetical protein 877258..878916 Escherichia coli UTI89 3993110 YP_539898.1 CDS ybjX NC_007946.1 878913 879905 R hypothetical protein complement(878913..879905) Escherichia coli UTI89 3993111 YP_539899.1 CDS UTI89_C0882 NC_007946.1 879974 880108 D hypothetical protein 879974..880108 Escherichia coli UTI89 3993112 YP_539900.2 CDS macA NC_007946.1 880020 881135 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 880020..881135 Escherichia coli UTI89 3993113 YP_539901.1 CDS ybjZ NC_007946.1 881132 883078 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 881132..883078 Escherichia coli UTI89 3993114 YP_539902.1 CDS cspD NC_007946.1 883151 883405 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(883151..883405) Escherichia coli UTI89 3993115 YP_539903.1 CDS UTI89_C0886 NC_007946.1 883249 883533 R hypothetical protein complement(883249..883533) Escherichia coli UTI89 3993116 YP_539904.1 CDS clpS NC_007946.1 883698 884018 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 883698..884018 Escherichia coli UTI89 3993117 YP_539905.2 CDS clpA NC_007946.1 884049 886325 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 884049..886325 Escherichia coli UTI89 3993118 YP_539906.1 CDS UTI89_C0889 NC_007946.1 886443 886715 R hypothetical protein complement(886443..886715) Escherichia coli UTI89 3993119 YP_539907.1 CDS UTI89_C0890 NC_007946.1 887218 888201 D hypothetical protein 887218..888201 Escherichia coli UTI89 3993120 YP_539908.1 CDS UTI89_C0891 NC_007946.1 888198 891431 D hypothetical protein 888198..891431 Escherichia coli UTI89 3993063 YP_539909.1 CDS UTI89_C0892 NC_007946.1 891761 893068 D hypothetical protein 891761..893068 Escherichia coli UTI89 3993064 YP_539910.1 CDS UTI89_C0893 NC_007946.1 893065 893280 D hypothetical protein 893065..893280 Escherichia coli UTI89 3993065 YP_539911.1 CDS UTI89_C0894 NC_007946.1 893347 893988 D hypothetical protein 893347..893988 Escherichia coli UTI89 3993066 YP_539912.1 CDS UTI89_C0895 NC_007946.1 893999 895000 D hypothetical protein 893999..895000 Escherichia coli UTI89 3993067 YP_539913.1 CDS UTI89_C0896 NC_007946.1 895011 895565 D hypothetical protein 895011..895565 Escherichia coli UTI89 3993068 YP_539914.1 CDS UTI89_C0898 NC_007946.1 896133 896453 D hypothetical protein 896133..896453 Escherichia coli UTI89 3993070 YP_539915.1 CDS infA NC_007946.1 896607 896825 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(896607..896825) Escherichia coli UTI89 3993071 YP_539916.1 CDS aat NC_007946.1 897110 897814 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(897110..897814) Escherichia coli UTI89 3993072 YP_539917.1 CDS cydC NC_007946.1 897856 899577 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(897856..899577) Escherichia coli UTI89 3993073 YP_539918.1 CDS cydD NC_007946.1 899578 901344 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(899578..901344) Escherichia coli UTI89 3993074 YP_539919.1 CDS trxB NC_007946.1 901467 902552 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(901467..902552) Escherichia coli UTI89 3993075 YP_539920.2 CDS lrp NC_007946.1 902976 903470 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 902976..903470 Escherichia coli UTI89 3993076 YP_539921.1 CDS ftsK NC_007946.1 903605 907648 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 903605..907648 Escherichia coli UTI89 3993077 YP_539922.1 CDS lolA NC_007946.1 907804 908418 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 907804..908418 Escherichia coli UTI89 3993078 YP_539923.1 CDS ycaJ NC_007946.1 908429 909772 D recombination factor protein RarA 908429..909772 Escherichia coli UTI89 3993079 YP_539924.1 CDS serS NC_007946.1 909863 911155 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 909863..911155 Escherichia coli UTI89 3993080 YP_539925.1 CDS UTI89_C0909 NC_007946.1 911268 911546 D hypothetical protein 911268..911546 Escherichia coli UTI89 3993081 YP_539926.1 CDS UTI89_C0910 NC_007946.1 911458 911598 R hypothetical protein complement(911458..911598) Escherichia coli UTI89 3992988 YP_539927.1 CDS UTI89_C0911 NC_007946.1 911530 911793 D hypothetical protein 911530..911793 Escherichia coli UTI89 3992989 YP_539928.1 CDS UTI89_C0912 NC_007946.1 911790 912050 R hypothetical protein complement(911790..912050) Escherichia coli UTI89 3992990 YP_539929.1 CDS UTI89_C0913 NC_007946.1 912093 913202 R bacteriophage late gene regulator complement(912093..913202) Escherichia coli UTI89 3992991 YP_539930.1 CDS UTI89_C0914 NC_007946.1 913360 914544 D tail sheath protein of prophage CP-933T 913360..914544 Escherichia coli UTI89 3992992 YP_539931.1 CDS UTI89_C0915 NC_007946.1 914544 915056 D tail fiber component of prophage CP-933T 914544..915056 Escherichia coli UTI89 3992993 YP_539932.1 CDS UTI89_C0916 NC_007946.1 915112 915486 D prophage CP-933T hypothetical protein 915112..915486 Escherichia coli UTI89 3992994 YP_539933.1 CDS UTI89_C0917 NC_007946.1 915414 915650 D phage tail protein 915414..915650 Escherichia coli UTI89 3992995 YP_539934.1 CDS UTI89_C0918 NC_007946.1 915637 918444 D phage tail protein 915637..918444 Escherichia coli UTI89 3992996 YP_539935.1 CDS UTI89_C0919 NC_007946.1 918451 918945 D tail fiber protein of prophage CP-933T 918451..918945 Escherichia coli UTI89 3992997 YP_539936.1 CDS pin NC_007946.1 918974 919573 R DNA-invertase complement(918974..919573) Escherichia coli UTI89 3992998 YP_539937.1 CDS UTI89_C0921 NC_007946.1 919678 920514 D tail fiber protein gpH 919678..920514 Escherichia coli UTI89 3992999 YP_539938.1 CDS UTI89_C0922 NC_007946.1 920518 921045 D tail fiber assembly 920518..921045 Escherichia coli UTI89 3993000 YP_539939.1 CDS UTI89_C0923 NC_007946.1 921074 921607 R tail fiber assembly protein complement(921074..921607) Escherichia coli UTI89 3993001 YP_539940.1 CDS UTI89_C0924 NC_007946.1 921610 923595 R phage protein gpH complement(921610..923595) Escherichia coli UTI89 3993002 YP_539941.1 CDS UTI89_C0925 NC_007946.1 923598 924128 R phage protein gpI complement(923598..924128) Escherichia coli UTI89 3993003 YP_539942.1 CDS UTI89_C0926 NC_007946.1 924121 925017 R phage baseplate assembly protein complement(924121..925017) Escherichia coli UTI89 3993004 YP_539943.1 CDS UTI89_C0927 NC_007946.1 925021 925371 R phage baseplate assembly protein complement(925021..925371) Escherichia coli UTI89 3993005 YP_539944.1 CDS UTI89_C0928 NC_007946.1 925368 925949 R phage protein gp15 complement(925368..925949) Escherichia coli UTI89 3993006 YP_539945.1 CDS UTI89_C0929 NC_007946.1 925946 926590 R tail completion phage protein complement(925946..926590) Escherichia coli UTI89 3993580 YP_539946.1 CDS UTI89_C0930 NC_007946.1 926574 927041 R tail completion phage protein complement(926574..927041) Escherichia coli UTI89 3993581 YP_539947.1 CDS UTI89_C0931 NC_007946.1 927179 927730 R hypothetical protein complement(927179..927730) Escherichia coli UTI89 3993582 YP_539948.1 CDS UTI89_C0932 NC_007946.1 927583 927975 R endolysin complement(927583..927975) Escherichia coli UTI89 3993583 YP_539949.1 CDS UTI89_C0933 NC_007946.1 927972 928295 R phage holin complement(927972..928295) Escherichia coli UTI89 3993584 YP_539950.1 CDS UTI89_C0934 NC_007946.1 928298 928498 R phage tail protein complement(928298..928498) Escherichia coli UTI89 3993585 YP_539951.1 CDS UTI89_C0935 NC_007946.1 928498 928992 R capsid completion protein complement(928498..928992) Escherichia coli UTI89 3993586 YP_539952.1 CDS UTI89_C0936 NC_007946.1 929094 929894 R hypothetical protein complement(929094..929894) Escherichia coli UTI89 3993587 YP_539953.1 CDS UTI89_C0937 NC_007946.1 929940 930992 R major capsid protein complement(929940..930992) Escherichia coli UTI89 3993588 YP_539954.1 CDS UTI89_C0938 NC_007946.1 931016 931852 R capsid scaffolding protein complement(931016..931852) Escherichia coli UTI89 3993589 YP_539955.1 CDS UTI89_C0939 NC_007946.1 932007 933758 D phage protein gpP 932007..933758 Escherichia coli UTI89 3993590 YP_539956.1 CDS UTI89_C0940 NC_007946.1 933758 934804 D hypothetical protein 933758..934804 Escherichia coli UTI89 3993591 YP_539957.1 CDS UTI89_C0941 NC_007946.1 934907 935263 D hypothetical protein 934907..935263 Escherichia coli UTI89 3993592 YP_539958.1 CDS UTI89_C0942 NC_007946.1 935295 935555 R hypothetical protein complement(935295..935555) Escherichia coli UTI89 3993593 YP_539959.1 CDS UTI89_C0943 NC_007946.1 935566 935829 R prophage CP-933R hypothetical protein complement(935566..935829) Escherichia coli UTI89 3993594 YP_539960.1 CDS UTI89_C0944 NC_007946.1 935831 936328 R hypothetical protein complement(935831..936328) Escherichia coli UTI89 3993595 YP_539961.1 CDS UTI89_C0945 NC_007946.1 936325 936639 R hypothetical protein complement(936325..936639) Escherichia coli UTI89 3993596 YP_539962.1 CDS UTI89_C0946 NC_007946.1 936636 936968 R ATP-dependent specificity component of ClpP serine protease, chaperone complement(936636..936968) Escherichia coli UTI89 3993597 YP_539963.1 CDS UTI89_C0947 NC_007946.1 937032 937343 R prophage CP-933T stability/partitioning protein complement(937032..937343) Escherichia coli UTI89 3993598 YP_539964.1 CDS UTI89_C0948 NC_007946.1 937348 938307 R prophage CP-933T stability/partitioning protein complement(937348..938307) Escherichia coli UTI89 3993599 YP_539965.1 CDS UTI89_C0949 NC_007946.1 938384 941206 R prophage CP-933T replication protein complement(938384..941206) Escherichia coli UTI89 3994214 YP_539966.1 CDS UTI89_C0950 NC_007946.1 941213 941578 R prophage CP-933T hypothetical protein complement(941213..941578) Escherichia coli UTI89 3994215 YP_539967.1 CDS UTI89_C0951 NC_007946.1 941651 941881 R prophage CP-933T hypothetical protein complement(941651..941881) Escherichia coli UTI89 3994216 YP_539968.1 CDS UTI89_C0952 NC_007946.1 941750 942025 D hypothetical protein 941750..942025 Escherichia coli UTI89 3994217 YP_539969.1 CDS UTI89_C0953 NC_007946.1 942252 943076 R serine protease complement(942252..943076) Escherichia coli UTI89 3994218 YP_539970.1 CDS UTI89_C0954 NC_007946.1 943073 943285 R hypothetical protein complement(943073..943285) Escherichia coli UTI89 3994219 YP_539972.1 CDS UTI89_C0956 NC_007946.1 943297 943596 R prophage CP-933T hypothetical protein complement(943297..943596) Escherichia coli UTI89 3994221 YP_539973.1 CDS UTI89_C0957 NC_007946.1 943593 943859 R hypothetical protein complement(943593..943859) Escherichia coli UTI89 3994222 YP_539974.1 CDS UTI89_C0958 NC_007946.1 943856 944059 R hypothetical protein complement(943856..944059) Escherichia coli UTI89 3994223 YP_539975.1 CDS UTI89_C0959 NC_007946.1 944083 944493 R prophage CP-933T hypothetical protein complement(944083..944493) Escherichia coli UTI89 3994224 YP_539976.1 CDS UTI89_C0960 NC_007946.1 944697 944939 R hypothetical protein complement(944697..944939) Escherichia coli UTI89 3994225 YP_539977.1 CDS UTI89_C0961 NC_007946.1 944951 945238 R hypothetical protein complement(944951..945238) Escherichia coli UTI89 3994226 YP_539978.1 CDS UTI89_C0962 NC_007946.1 945249 945599 R hypothetical protein complement(945249..945599) Escherichia coli UTI89 3994227 YP_539979.1 CDS UTI89_C0963 NC_007946.1 945933 946355 R hypothetical protein complement(945933..946355) Escherichia coli UTI89 3994228 YP_539980.1 CDS UTI89_C0964 NC_007946.1 946360 946881 R hypothetical protein complement(946360..946881) Escherichia coli UTI89 3994229 YP_539981.1 CDS UTI89_C0965 NC_007946.1 946985 947326 D bacteriophage WPhi phage protein C 946985..947326 Escherichia coli UTI89 3994230 YP_539982.1 CDS UTI89_C0966 NC_007946.1 947396 948388 D phage integrase 947396..948388 Escherichia coli UTI89 3994231 YP_539983.1 CDS dmsA NC_007946.1 948688 951132 D anaerobic dimethyl sulfoxide reductase chain A 948688..951132 Escherichia coli UTI89 3994232 YP_539984.1 CDS dmsB NC_007946.1 951143 951760 D anaerobic dimethyl sulfoxide reductase subunit B 951143..951760 Escherichia coli UTI89 3993389 YP_539985.1 CDS dmsC NC_007946.1 951762 952625 D anaerobic dimethyl sulfoxide reductase subunit C 951762..952625 Escherichia coli UTI89 3993390 YP_539986.1 CDS ycaC NC_007946.1 952661 953386 R protein YcaC complement(952661..953386) Escherichia coli UTI89 3993391 YP_539987.1 CDS UTI89_C0971 NC_007946.1 953442 953570 R hypothetical protein complement(953442..953570) Escherichia coli UTI89 3993392 YP_539988.1 CDS ycaD NC_007946.1 953601 954749 D MFS family transporter protein 953601..954749 Escherichia coli UTI89 3993393 YP_539989.2 CDS pflA NC_007946.1 954846 955586 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(954846..955586) Escherichia coli UTI89 3993394 YP_539990.1 CDS pflB NC_007946.1 955778 958060 R formate acetyltransferase 1 complement(955778..958060) Escherichia coli UTI89 3993395 YP_539991.1 CDS focA NC_007946.1 958115 959311 R formate transporter complement(958115..959311) Escherichia coli UTI89 3993396 YP_539992.1 CDS ycaO NC_007946.1 959378 961171 R hypothetical protein complement(959378..961171) Escherichia coli UTI89 3993397 YP_539993.1 CDS ycaP NC_007946.1 961268 961960 D hypothetical protein 961268..961960 Escherichia coli UTI89 3993398 YP_539994.1 CDS serC NC_007946.1 962159 963247 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 962159..963247 Escherichia coli UTI89 3993399 YP_539995.1 CDS aroA NC_007946.1 963318 964601 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 963318..964601 Escherichia coli UTI89 3993400 YP_539996.1 CDS ycaL NC_007946.1 964762 965535 D metalloprotease YcaL 964762..965535 Escherichia coli UTI89 3993401 YP_539997.1 CDS cmk NC_007946.1 965708 966391 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 965708..966391 Escherichia coli UTI89 3993402 YP_539998.1 CDS rpsA NC_007946.1 966502 968175 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 966502..968175 Escherichia coli UTI89 3993403 YP_539999.1 CDS ihfB NC_007946.1 968335 968619 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 968335..968619 Escherichia coli UTI89 3993404 YP_540000.2 CDS ycaI NC_007946.1 968825 971089 D hypothetical protein 968825..971089 Escherichia coli UTI89 3993405 YP_540001.1 CDS msbA NC_007946.1 971126 972874 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 971126..972874 Escherichia coli UTI89 3993406 YP_540002.1 CDS lpxK NC_007946.1 972871 973857 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 972871..973857 Escherichia coli UTI89 3993407 YP_540003.1 CDS ycaQ NC_007946.1 973894 975126 D hypothetical protein 973894..975126 Escherichia coli UTI89 3993408 YP_540004.1 CDS ycaR NC_007946.1 975178 975360 D hypothetical protein 975178..975360 Escherichia coli UTI89 3992815 YP_540005.1 CDS kdsB NC_007946.1 975357 976103 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 975357..976103 Escherichia coli UTI89 3992816 YP_540006.1 CDS ycbJ NC_007946.1 976257 977150 D hypothetical protein 976257..977150 Escherichia coli UTI89 3992817 YP_540007.1 CDS ycbC NC_007946.1 977127 977906 R hypothetical protein complement(977127..977906) Escherichia coli UTI89 3992818 YP_540008.1 CDS UTI89_C0992 NC_007946.1 977809 977973 R hypothetical protein complement(977809..977973) Escherichia coli UTI89 3992819 YP_540009.1 CDS smtA NC_007946.1 978030 978827 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 978030..978827 Escherichia coli UTI89 3992820 YP_540010.1 CDS mukF NC_007946.1 978824 980146 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 978824..980146 Escherichia coli UTI89 3992821 YP_540011.1 CDS mukE NC_007946.1 980100 980831 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 980100..980831 Escherichia coli UTI89 3992822 YP_540012.1 CDS mukB NC_007946.1 980831 985291 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 980831..985291 Escherichia coli UTI89 3992823 YP_540013.1 CDS ycbB NC_007946.1 985552 987399 D hypothetical protein 985552..987399 Escherichia coli UTI89 3992824 YP_540014.1 CDS ycbK NC_007946.1 987571 988128 D hypothetical protein 987571..988128 Escherichia coli UTI89 3992825 YP_540015.1 CDS ycbL NC_007946.1 988155 988802 D hypothetical protein 988155..988802 Escherichia coli UTI89 3992826 YP_540016.1 CDS aspC NC_007946.1 988852 990042 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(988852..990042) Escherichia coli UTI89 3992827 YP_540017.1 CDS ompF NC_007946.1 990227 991315 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(990227..991315) Escherichia coli UTI89 3992828 YP_540018.1 CDS asnC NC_007946.1 991917 993317 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(991917..993317) Escherichia coli UTI89 3992829 YP_540019.1 CDS pncB NC_007946.1 993486 994736 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(993486..994736) Escherichia coli UTI89 3992830 YP_540020.1 CDS pepN NC_007946.1 994954 997566 D aminopeptidase 994954..997566 Escherichia coli UTI89 3992831 YP_540021.1 CDS ssuB NC_007946.1 997761 998528 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonate ABC transporter ATP-binding protein complement(997761..998528) Escherichia coli UTI89 3992832 YP_540022.1 CDS ssuC NC_007946.1 998525 999319 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate ABC transporter permease complement(998525..999319) Escherichia coli UTI89 3992833 YP_540023.1 CDS ycbN NC_007946.1 999328 1000473 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(999328..1000473) Escherichia coli UTI89 3994706 YP_540024.2 CDS ycbO NC_007946.1 1000470 1001429 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1000470..1001429) Escherichia coli UTI89 3994707 YP_540025.1 CDS ycbP NC_007946.1 1001422 1001997 R NAD(P)H-dependent FMN reductase complement(1001422..1001997) Escherichia coli UTI89 3994708 YP_540026.1 CDS pyrD NC_007946.1 1002207 1003244 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1002207..1003244 Escherichia coli UTI89 3994709 YP_540027.1 CDS ycbW NC_007946.1 1003382 1003960 D hypothetical protein 1003382..1003960 Escherichia coli UTI89 3994710 YP_540028.1 CDS ycbX NC_007946.1 1003957 1005066 R hypothetical protein complement(1003957..1005066) Escherichia coli UTI89 3994711 YP_540029.1 CDS rlmL NC_007946.1 1005164 1007272 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1005164..1007272 Escherichia coli UTI89 3994712 YP_540030.1 CDS uup NC_007946.1 1007284 1009191 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1007284..1009191 Escherichia coli UTI89 3994713 YP_540031.1 CDS pqiA NC_007946.1 1009321 1010574 D paraquat-inducible protein A 1009321..1010574 Escherichia coli UTI89 3994714 YP_540032.1 CDS pqiB NC_007946.1 1010519 1012219 D paraquat-inducible protein B 1010519..1012219 Escherichia coli UTI89 3994715 YP_540033.1 CDS ymbA NC_007946.1 1012216 1012779 D hypothetical protein 1012216..1012779 Escherichia coli UTI89 3994716 YP_540034.1 CDS rmf NC_007946.1 1013035 1013202 D ribosome modulation factor 1013035..1013202 Escherichia coli UTI89 3994717 YP_540035.2 CDS fabA NC_007946.1 1013272 1013790 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1013272..1013790) Escherichia coli UTI89 3994718 YP_540036.1 CDS UTI89_C1020 NC_007946.1 1013859 1015619 R protease La-like protein complement(1013859..1015619) Escherichia coli UTI89 3994719 YP_540037.1 CDS ycbG NC_007946.1 1015805 1016257 D hypothetical protein 1015805..1016257 Escherichia coli UTI89 3994720 YP_540038.1 CDS ompA NC_007946.1 1016335 1017462 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein OmpA complement(1016335..1017462) Escherichia coli UTI89 3994721 YP_540039.1 CDS UTI89_C1023 NC_007946.1 1017529 1017747 D hypothetical protein 1017529..1017747 Escherichia coli UTI89 3994722 YP_540040.1 CDS sulA NC_007946.1 1017731 1018246 R SOS cell division inhibitor complement(1017731..1018246) Escherichia coli UTI89 3994723 YP_540041.1 CDS yccR NC_007946.1 1018459 1019088 D hypothetical protein 1018459..1019088 Escherichia coli UTI89 3994724 YP_540042.1 CDS yccS NC_007946.1 1019051 1021213 R hypothetical protein complement(1019051..1021213) Escherichia coli UTI89 3994725 YP_540043.1 CDS yccF NC_007946.1 1021223 1021669 R hypothetical protein complement(1021223..1021669) Escherichia coli UTI89 3993121 YP_540044.2 CDS helD NC_007946.1 1021792 1023846 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1021792..1023846 Escherichia coli UTI89 3993122 YP_540045.1 CDS mgsA NC_007946.1 1023878 1024345 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1023878..1024345) Escherichia coli UTI89 3993123 YP_540046.1 CDS yccT NC_007946.1 1024432 1025094 R hypothetical protein complement(1024432..1025094) Escherichia coli UTI89 3993124 YP_540047.1 CDS UTI89_C1031 NC_007946.1 1025186 1025680 D hypothetical protein 1025186..1025680 Escherichia coli UTI89 3993125 YP_540048.1 CDS UTI89_C1032 NC_007946.1 1025649 1026044 D hypothetical protein 1025649..1026044 Escherichia coli UTI89 3993126 YP_540049.1 CDS yccV NC_007946.1 1025725 1026093 R heat shock protein HspQ complement(1025725..1026093) Escherichia coli UTI89 3993127 YP_540050.1 CDS yccW NC_007946.1 1026100 1027290 R hypothetical protein complement(1026100..1027290) Escherichia coli UTI89 3993128 YP_540051.1 CDS UTI89_C1035 NC_007946.1 1027265 1027663 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1027265..1027663 Escherichia coli UTI89 3993129 YP_540052.1 CDS yccK NC_007946.1 1027660 1027989 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1027660..1027989) Escherichia coli UTI89 3993130 YP_540053.1 CDS yccA NC_007946.1 1028081 1028740 R hypothetical protein complement(1028081..1028740) Escherichia coli UTI89 3993131 YP_540055.1 CDS hyaA NC_007946.1 1029434 1030579 D hydrogenase-1 small chain 1029434..1030579 Escherichia coli UTI89 3993134 YP_540056.1 CDS hyaB NC_007946.1 1030576 1032369 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1030576..1032369 Escherichia coli UTI89 3993135 YP_540057.1 CDS hyaC NC_007946.1 1032388 1033095 D hydrogenase 1 b-type cytochrome subunit 1032388..1033095 Escherichia coli UTI89 3993136 YP_540058.1 CDS hyaD NC_007946.1 1033092 1033679 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1033092..1033679 Escherichia coli UTI89 3993137 YP_540059.1 CDS hyaE NC_007946.1 1033676 1034074 D involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1033676..1034074 Escherichia coli UTI89 3993138 YP_540060.1 CDS hyaF NC_007946.1 1034071 1034928 D hydrogenase-1 operon protein HyaF 1034071..1034928 Escherichia coli UTI89 3994627 YP_540061.1 CDS appC NC_007946.1 1035062 1036606 D third cytochrome oxidase subunit I 1035062..1036606 Escherichia coli UTI89 3994628 YP_540062.1 CDS appB NC_007946.1 1036618 1037754 D third cytochrome oxidase subunit II 1036618..1037754 Escherichia coli UTI89 3994629 YP_540063.1 CDS yccB NC_007946.1 1037767 1037859 D expressed during stationary phase; hypothetical protein 1037767..1037859 Escherichia coli UTI89 3994630 YP_540064.1 CDS appA NC_007946.1 1037909 1039249 D phosphoanhydride phosphorylase 1037909..1039249 Escherichia coli UTI89 3994631 YP_540065.1 CDS cspH NC_007946.1 1039237 1039449 R cold shock-like protein H complement(1039237..1039449) Escherichia coli UTI89 3994632 YP_540066.1 CDS cspG NC_007946.1 1039735 1039947 D cold shock protein CspG 1039735..1039947 Escherichia coli UTI89 3994633 YP_540067.1 CDS sfa NC_007946.1 1040088 1040351 D cold shock gene 1040088..1040351 Escherichia coli UTI89 3994634 YP_540068.1 CDS gnsB NC_007946.1 1040341 1040514 D protein that affects unsaturated fatty acid abundance 1040341..1040514 Escherichia coli UTI89 3994635 YP_540069.1 CDS UTI89_C1054 NC_007946.1 1040356 1040529 R hypothetical protein complement(1040356..1040529) Escherichia coli UTI89 3994636 YP_540070.1 CDS yccM NC_007946.1 1040563 1041636 R electron transport protein YccM complement(1040563..1041636) Escherichia coli UTI89 3994637 YP_540071.1 CDS torS NC_007946.1 1041719 1044451 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1041719..1044451) Escherichia coli UTI89 3994638 YP_540073.1 CDS torT NC_007946.1 1044534 1045562 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1044534..1045562 Escherichia coli UTI89 3994640 YP_540074.1 CDS torR NC_007946.1 1045535 1046227 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1045535..1046227) Escherichia coli UTI89 3994641 YP_540075.1 CDS torC NC_007946.1 1046319 1047539 D cytochrome c-type protein TorC 1046319..1047539 Escherichia coli UTI89 3994642 YP_540076.1 CDS torA NC_007946.1 1047539 1050085 D trimethylamine-N-oxide reductase 1 1047539..1050085 Escherichia coli UTI89 3994643 YP_540077.1 CDS torD NC_007946.1 1050049 1050681 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1050049..1050681 Escherichia coli UTI89 3994644 YP_540078.1 CDS yccD NC_007946.1 1051037 1051342 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1051037..1051342) Escherichia coli UTI89 3994645 YP_540079.1 CDS cbpA NC_007946.1 1051342 1052262 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1051342..1052262) Escherichia coli UTI89 3994646 YP_540080.1 CDS agp NC_007946.1 1052797 1054038 D glucose-1-phosphatase/inositol phosphatase 1052797..1054038 Escherichia coli UTI89 3989940 YP_540081.1 CDS yccJ NC_007946.1 1054076 1054303 R hypothetical protein complement(1054076..1054303) Escherichia coli UTI89 3989941 YP_540082.1 CDS wrbA NC_007946.1 1054324 1054920 R stationary phase that binds TrpR repressor; TrpR binding protein WrbA complement(1054324..1054920) Escherichia coli UTI89 3989942 YP_540083.1 CDS UTI89_C1068 NC_007946.1 1055324 1055482 D hypothetical protein 1055324..1055482 Escherichia coli UTI89 3989943 YP_540084.1 CDS UTI89_C1069 NC_007946.1 1055479 1055616 D hypothetical protein 1055479..1055616 Escherichia coli UTI89 3989944 YP_540085.1 CDS nmoB NC_007946.1 1056792 1057367 R 4-hydroxyphenylacetate 3-monooxygenase small chain complement(1056792..1057367) Escherichia coli UTI89 3989945 YP_540086.1 CDS UTI89_C1071 NC_007946.1 1057297 1057887 R hypothetical protein complement(1057297..1057887) Escherichia coli UTI89 3989946 YP_540087.1 CDS ycdJ NC_007946.1 1057897 1058724 R hypothetical protein complement(1057897..1058724) Escherichia coli UTI89 3989947 YP_540088.1 CDS ycdK NC_007946.1 1058705 1059091 R hypothetical protein complement(1058705..1059091) Escherichia coli UTI89 3989948 YP_540089.1 CDS ycdL NC_007946.1 1059103 1059837 R isochorismatase YcdL complement(1059103..1059837) Escherichia coli UTI89 3989949 YP_540090.1 CDS ycdM NC_007946.1 1059795 1060976 R monooxygenase YcdM complement(1059795..1060976) Escherichia coli UTI89 3989950 YP_540091.1 CDS ycdC NC_007946.1 1061146 1061811 D transcriptional regulator YcdC 1061146..1061811 Escherichia coli UTI89 3989951 YP_540092.2 CDS putA NC_007946.1 1061851 1065813 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1061851..1065813) Escherichia coli UTI89 3989952 YP_540093.1 CDS UTI89_C1078 NC_007946.1 1065868 1066077 D hypothetical protein 1065868..1066077 Escherichia coli UTI89 3989953 YP_540094.1 CDS putP NC_007946.1 1066236 1067744 D sodium/proline symporter 1066236..1067744 Escherichia coli UTI89 3989954 YP_540095.1 CDS UTI89_C1080 NC_007946.1 1067955 1068794 D hypothetical protein 1067955..1068794 Escherichia coli UTI89 3989955 YP_540096.1 CDS ycdO NC_007946.1 1068852 1069979 D hypothetical protein 1068852..1069979 Escherichia coli UTI89 3989956 YP_540097.1 CDS ycdB NC_007946.1 1069985 1071256 D hypothetical protein 1069985..1071256 Escherichia coli UTI89 3989957 YP_540098.1 CDS phoH NC_007946.1 1071747 1072670 D hypothetical protein 1071747..1072670 Escherichia coli UTI89 3989958 YP_540099.1 CDS pgaD NC_007946.1 1072720 1073133 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein complement(1072720..1073133) Escherichia coli UTI89 3991931 YP_540100.1 CDS ycdQ NC_007946.1 1073135 1074460 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1073135..1074460) Escherichia coli UTI89 3991932 YP_540101.1 CDS pgaB NC_007946.1 1074453 1076471 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1074453..1076471) Escherichia coli UTI89 3991933 YP_540102.1 CDS pgaA NC_007946.1 1076480 1078903 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1076480..1078903) Escherichia coli UTI89 3991934 YP_540103.1 CDS ycdT NC_007946.1 1079368 1080858 D hypothetical protein 1079368..1080858 Escherichia coli UTI89 3991935 YP_540104.1 CDS UTI89_C1089 NC_007946.1 1081137 1082339 D P4 family integrase 1081137..1082339 Escherichia coli UTI89 3991936 YP_540105.1 CDS UTI89_C1090 NC_007946.1 1082526 1084343 R hypothetical protein complement(1082526..1084343) Escherichia coli UTI89 3991937 YP_540106.1 CDS UTI89_C1091 NC_007946.1 1084628 1084792 D hypothetical protein 1084628..1084792 Escherichia coli UTI89 3991938 YP_540107.1 CDS UTI89_C1092 NC_007946.1 1084840 1085304 D transposase 1084840..1085304 Escherichia coli UTI89 3991939 YP_540108.1 CDS UTI89_C1093 NC_007946.1 1085457 1085753 D prophage regulatory protein 1085457..1085753 Escherichia coli UTI89 3991940 YP_540109.1 CDS yfjI NC_007946.1 1086378 1087829 D hypothetical protein 1086378..1087829 Escherichia coli UTI89 3991941 YP_540110.1 CDS UTI89_C1095 NC_007946.1 1088785 1089378 D hypothetical protein 1088785..1089378 Escherichia coli UTI89 3991942 YP_540111.1 CDS UTI89_C1096 NC_007946.1 1089477 1089734 R hypothetical protein complement(1089477..1089734) Escherichia coli UTI89 3991943 YP_540112.1 CDS UTI89_C1097 NC_007946.1 1089480 1089686 D hypothetical protein 1089480..1089686 Escherichia coli UTI89 3991944 YP_540113.1 CDS UTI89_C1098 NC_007946.1 1089855 1091855 R hypothetical protein complement(1089855..1091855) Escherichia coli UTI89 3991945 YP_540114.1 CDS UTI89_C1099 NC_007946.1 1091770 1092936 R aminotransferase complement(1091770..1092936) Escherichia coli UTI89 3991946 YP_540115.1 CDS UTI89_C1100 NC_007946.1 1093070 1093336 R tagatose-bisphosphate aldolase 2 complement(1093070..1093336) Escherichia coli UTI89 3991947 YP_540116.1 CDS UTI89_C1101 NC_007946.1 1093358 1093981 R hypothetical protein complement(1093358..1093981) Escherichia coli UTI89 3991948 YP_540117.1 CDS UTI89_C1102 NC_007946.1 1094034 1094297 R hypothetical protein complement(1094034..1094297) Escherichia coli UTI89 3991949 YP_540118.1 CDS UTI89_C1103 NC_007946.1 1095846 1096370 D hypothetical protein 1095846..1096370 Escherichia coli UTI89 3991950 YP_540119.1 CDS UTI89_C1104 NC_007946.1 1096409 1096921 D hypothetical protein 1096409..1096921 Escherichia coli UTI89 3991350 YP_540120.1 CDS UTI89_C1105 NC_007946.1 1096433 1096609 R hypothetical protein complement(1096433..1096609) Escherichia coli UTI89 3991351 YP_540121.1 CDS UTI89_C1106 NC_007946.1 1097163 1097732 D hypothetical protein 1097163..1097732 Escherichia coli UTI89 3991352 YP_540122.1 CDS sfaC NC_007946.1 1098007 1098291 R S fimbrial switch regulatory protein complement(1098007..1098291) Escherichia coli UTI89 3991353 YP_540123.1 CDS sfaB NC_007946.1 1098647 1098976 D S fimbrial switch regulatory protein 1098647..1098976 Escherichia coli UTI89 3991354 YP_540124.1 CDS sfaA NC_007946.1 1099351 1099896 D S fimbriae major subunit SfaA 1099351..1099896 Escherichia coli UTI89 3991355 YP_540125.1 CDS sfaD NC_007946.1 1099958 1100506 D S fimbriae minor subunit SfaD 1099958..1100506 Escherichia coli UTI89 3991356 YP_540126.1 CDS sfaE NC_007946.1 1100547 1101242 D S fimbriae periplasmic chaperone SfaE 1100547..1101242 Escherichia coli UTI89 3991357 YP_540127.1 CDS sfaF NC_007946.1 1101264 1103942 D S fimbriae outer membrane usher 1101264..1103942 Escherichia coli UTI89 3991358 YP_540128.1 CDS sfaG NC_007946.1 1103955 1104482 D S fimbriae minor subunit SfaG 1103955..1104482 Escherichia coli UTI89 3991359 YP_540129.1 CDS sfaS NC_007946.1 1104504 1104995 D S fimbriae minor subunit SfaS 1104504..1104995 Escherichia coli UTI89 3991360 YP_540130.1 CDS sfaH NC_007946.1 1104988 1105956 D S fimbriae minor subunit SfaH 1104988..1105956 Escherichia coli UTI89 3991361 YP_540131.1 CDS UTI89_C1116 NC_007946.1 1106260 1107000 D hypothetical protein 1106260..1107000 Escherichia coli UTI89 3991362 YP_540132.1 CDS focX NC_007946.1 1107147 1107698 D regulatory protein 1107147..1107698 Escherichia coli UTI89 3991363 YP_540133.1 CDS iroN NC_007946.1 1108192 1110369 D Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 1108192..1110369 Escherichia coli UTI89 3991364 YP_540134.1 CDS iroE NC_007946.1 1110414 1111370 R IroE protein complement(1110414..1111370) Escherichia coli UTI89 3991365 YP_540135.1 CDS iroD NC_007946.1 1111455 1112684 R IroD protein complement(1111455..1112684) Escherichia coli UTI89 3991366 YP_540136.1 CDS iroC NC_007946.1 1112788 1116573 R IroC protein complement(1112788..1116573) Escherichia coli UTI89 3991367 YP_540137.1 CDS iroB NC_007946.1 1116587 1117750 R glucosyltransferase complement(1116587..1117750) Escherichia coli UTI89 3991368 YP_540138.1 CDS UTI89_C1123 NC_007946.1 1118244 1118558 D hypothetical protein 1118244..1118558 Escherichia coli UTI89 3993370 YP_540139.1 CDS UTI89_C1124 NC_007946.1 1118597 1118959 R hypothetical protein complement(1118597..1118959) Escherichia coli UTI89 3993371 YP_540140.1 CDS UTI89_C1125 NC_007946.1 1119826 1120260 D hypothetical protein 1119826..1120260 Escherichia coli UTI89 3993372 YP_540141.1 CDS UTI89_C1127 NC_007946.1 1120823 1121281 R transposase complement(1120823..1121281) Escherichia coli UTI89 3993374 YP_540142.1 CDS UTI89_C1128 NC_007946.1 1121293 1122186 R hypothetical protein complement(1121293..1122186) Escherichia coli UTI89 3993375 YP_540143.1 CDS UTI89_C1129 NC_007946.1 1122532 1124502 D outer membrane heme/hemoglobin receptor 1122532..1124502 Escherichia coli UTI89 3993376 YP_540144.1 CDS UTI89_C1130 NC_007946.1 1124521 1125312 D hypothetical protein 1124521..1125312 Escherichia coli UTI89 3993377 YP_540145.1 CDS UTI89_C1131 NC_007946.1 1125513 1126775 D hypothetical protein 1125513..1126775 Escherichia coli UTI89 3993378 YP_540146.1 CDS UTI89_C1132 NC_007946.1 1126882 1127064 R hypothetical protein complement(1126882..1127064) Escherichia coli UTI89 3993379 YP_540147.1 CDS UTI89_C1133 NC_007946.1 1127725 1128861 D hypothetical protein 1127725..1128861 Escherichia coli UTI89 3993380 YP_540148.1 CDS UTI89_C1134 NC_007946.1 1129663 1129989 R hypothetical protein complement(1129663..1129989) Escherichia coli UTI89 3993381 YP_540149.1 CDS UTI89_C1135 NC_007946.1 1130377 1130736 R hypothetical protein complement(1130377..1130736) Escherichia coli UTI89 3993382 YP_540150.1 CDS UTI89_C1136 NC_007946.1 1130945 1131274 R hypothetical protein complement(1130945..1131274) Escherichia coli UTI89 3993383 YP_540151.1 CDS UTI89_C1137 NC_007946.1 1131288 1131593 R hypothetical protein complement(1131288..1131593) Escherichia coli UTI89 3993384 YP_540152.1 CDS UTI89_C1138 NC_007946.1 1132408 1133280 D hypothetical protein 1132408..1133280 Escherichia coli UTI89 3993385 YP_540153.1 CDS UTI89_C1139 NC_007946.1 1133653 1136499 D autotransporter 1133653..1136499 Escherichia coli UTI89 3993386 YP_540154.1 CDS yafZ1 NC_007946.1 1136830 1137651 D hypothetical protein 1136830..1137651 Escherichia coli UTI89 3993387 YP_540155.1 CDS UTI89_C1141 NC_007946.1 1136836 1137693 R hypothetical protein complement(1136836..1137693) Escherichia coli UTI89 3993388 YP_540156.1 CDS UTI89_C1142 NC_007946.1 1137672 1137896 D hypothetical protein 1137672..1137896 Escherichia coli UTI89 3994156 YP_540157.1 CDS yafX1 NC_007946.1 1137918 1138463 D hypothetical protein 1137918..1138463 Escherichia coli UTI89 3994157 YP_540158.1 CDS UTI89_C1144 NC_007946.1 1137984 1138943 R hypothetical protein complement(1137984..1138943) Escherichia coli UTI89 3994158 YP_540159.1 CDS yeeS3 NC_007946.1 1138479 1138955 D radC-like protein YeeS 1138479..1138955 Escherichia coli UTI89 3994159 YP_540160.1 CDS yeeT3 NC_007946.1 1139018 1139239 D hypothetical protein 1139018..1139239 Escherichia coli UTI89 3994160 YP_540161.1 CDS UTI89_C1147 NC_007946.1 1139258 1139902 D hypothetical protein 1139258..1139902 Escherichia coli UTI89 3994161 YP_540162.1 CDS UTI89_C1148 NC_007946.1 1139862 1140329 D intergenic-region protein 1139862..1140329 Escherichia coli UTI89 3994162 YP_540163.1 CDS UTI89_C1149 NC_007946.1 1140376 1140750 D hypothetical protein 1140376..1140750 Escherichia coli UTI89 3994163 YP_540164.1 CDS UTI89_C1150 NC_007946.1 1140750 1141238 D hypothetical protein 1140750..1141238 Escherichia coli UTI89 3994164 YP_540165.1 CDS UTI89_C1151 NC_007946.1 1141250 1141447 D hypothetical protein 1141250..1141447 Escherichia coli UTI89 3994165 YP_540166.1 CDS UTI89_C1152 NC_007946.1 1141540 1142382 D hypothetical protein 1141540..1142382 Escherichia coli UTI89 3994166 YP_540167.1 CDS ycdW NC_007946.1 1142814 1143791 D dehydrogenase 1142814..1143791 Escherichia coli UTI89 3994168 YP_540168.1 CDS ycdX NC_007946.1 1143846 1144583 D hydrolase 1143846..1144583 Escherichia coli UTI89 3994169 YP_540169.1 CDS ycdY NC_007946.1 1144607 1145161 D hypothetical protein 1144607..1145161 Escherichia coli UTI89 3994170 YP_540170.1 CDS ycdZ NC_007946.1 1145215 1145754 D hypothetical protein 1145215..1145754 Escherichia coli UTI89 3994171 YP_540171.1 CDS csgG NC_007946.1 1145819 1146652 R curli production protein CsgG complement(1145819..1146652) Escherichia coli UTI89 3994172 YP_540172.1 CDS csgF NC_007946.1 1146679 1147095 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1146679..1147095) Escherichia coli UTI89 3994173 YP_540173.1 CDS csgE NC_007946.1 1147120 1147509 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1147120..1147509) Escherichia coli UTI89 3993926 YP_540174.1 CDS csgD NC_007946.1 1147514 1148164 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1147514..1148164) Escherichia coli UTI89 3993927 YP_540175.1 CDS UTI89_C1162 NC_007946.1 1148138 1148278 D hypothetical protein 1148138..1148278 Escherichia coli UTI89 3993928 YP_540176.1 CDS UTI89_C1163 NC_007946.1 1148689 1148823 R hypothetical protein complement(1148689..1148823) Escherichia coli UTI89 3993929 YP_540177.1 CDS csgB NC_007946.1 1148890 1149372 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1148890..1149372 Escherichia coli UTI89 3993930 YP_540178.1 CDS csgA NC_007946.1 1149413 1149868 D cryptic curlin major subunit 1149413..1149868 Escherichia coli UTI89 3993931 YP_540179.1 CDS csgC NC_007946.1 1149927 1150259 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1149927..1150259 Escherichia coli UTI89 3993932 YP_540180.1 CDS UTI89_C1167 NC_007946.1 1150380 1150691 D hypothetical protein 1150380..1150691 Escherichia coli UTI89 3993933 YP_540181.1 CDS ymdB NC_007946.1 1150786 1151319 D hypothetical protein 1150786..1151319 Escherichia coli UTI89 3993934 YP_540182.1 CDS ymdC NC_007946.1 1151261 1152742 D synthase 1151261..1152742 Escherichia coli UTI89 3993935 YP_540183.1 CDS mdoC NC_007946.1 1152750 1153907 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1152750..1153907) Escherichia coli UTI89 3993936 YP_540184.1 CDS UTI89_C1171 NC_007946.1 1153952 1154095 R hypothetical protein complement(1153952..1154095) Escherichia coli UTI89 3993937 YP_540185.1 CDS mdoG NC_007946.1 1154283 1155836 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1154283..1155836 Escherichia coli UTI89 3993938 YP_540186.1 CDS mdoH NC_007946.1 1155799 1158372 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1155799..1158372 Escherichia coli UTI89 3993939 YP_540187.1 CDS UTI89_C1174 NC_007946.1 1158381 1158596 D hypothetical protein 1158381..1158596 Escherichia coli UTI89 3993940 YP_540188.1 CDS yceK NC_007946.1 1158544 1158771 D hypothetical protein 1158544..1158771 Escherichia coli UTI89 3993941 YP_540189.1 CDS msyB NC_007946.1 1158772 1159149 R hypothetical protein complement(1158772..1159149) Escherichia coli UTI89 3993942 YP_540190.1 CDS yceE NC_007946.1 1159229 1160455 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1159229..1160455) Escherichia coli UTI89 3993943 YP_540191.1 CDS htrB NC_007946.1 1160627 1161610 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1160627..1161610) Escherichia coli UTI89 3993944 YP_540192.1 CDS yceA NC_007946.1 1161718 1162824 D hypothetical protein 1161718..1162824 Escherichia coli UTI89 3993945 YP_540193.1 CDS yceI NC_007946.1 1162866 1163441 R hypothetical protein complement(1162866..1163441) Escherichia coli UTI89 3994726 YP_540194.1 CDS UTI89_C1181 NC_007946.1 1163445 1164023 R cytochrome b561-like protein 2 complement(1163445..1164023) Escherichia coli UTI89 3994727 YP_540195.1 CDS UTI89_C1182 NC_007946.1 1164001 1164147 D hypothetical protein 1164001..1164147 Escherichia coli UTI89 3994728 YP_540196.1 CDS yceO NC_007946.1 1164272 1164412 R hypothetical protein complement(1164272..1164412) Escherichia coli UTI89 3994729 YP_540197.1 CDS solA NC_007946.1 1164433 1165551 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1164433..1165551) Escherichia coli UTI89 3994730 YP_540198.2 CDS bssS NC_007946.1 1165666 1165920 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1165666..1165920) Escherichia coli UTI89 3994731 YP_540199.1 CDS UTI89_C1186 NC_007946.1 1166210 1166512 R DNA damage-inducible protein I complement(1166210..1166512) Escherichia coli UTI89 3994732 YP_540200.1 CDS pyrC NC_007946.1 1166529 1167575 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1166529..1167575) Escherichia coli UTI89 3994733 YP_540201.1 CDS yceB NC_007946.1 1167681 1168298 R hypothetical protein complement(1167681..1168298) Escherichia coli UTI89 3994734 YP_540202.1 CDS grxB NC_007946.1 1168375 1169022 R cofactor involved in the reduction of disulfides; glutaredoxin 2 complement(1168375..1169022) Escherichia coli UTI89 3994735 YP_540203.2 CDS yceL NC_007946.1 1169086 1170294 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1169086..1170294) Escherichia coli UTI89 3994736 YP_540204.1 CDS rimJ NC_007946.1 1170530 1171114 D ribosomal-protein-S5-alanine N-acetyltransferase 1170530..1171114 Escherichia coli UTI89 3994737 YP_540205.1 CDS yceH NC_007946.1 1171125 1171772 D hypothetical protein 1171125..1171772 Escherichia coli UTI89 3994738 YP_540206.1 CDS mviM NC_007946.1 1171774 1172697 D virulence factor 1171774..1172697 Escherichia coli UTI89 3994739 YP_540207.1 CDS mviN NC_007946.1 1172807 1174342 D virulence factor 1172807..1174342 Escherichia coli UTI89 3994740 YP_540208.1 CDS flgN NC_007946.1 1174382 1174798 R flagellar synthesis protein FlgN complement(1174382..1174798) Escherichia coli UTI89 3994741 YP_540209.1 CDS flgM NC_007946.1 1174803 1175096 R regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM complement(1174803..1175096) Escherichia coli UTI89 3994742 YP_540210.1 CDS flgA NC_007946.1 1175172 1175831 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1175172..1175831) Escherichia coli UTI89 3994743 YP_540211.1 CDS flgB NC_007946.1 1175986 1176402 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1175986..1176402 Escherichia coli UTI89 3994744 YP_540212.1 CDS flgC NC_007946.1 1176406 1176810 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1176406..1176810 Escherichia coli UTI89 3994422 YP_540213.1 CDS flgD NC_007946.1 1176822 1177517 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1176822..1177517 Escherichia coli UTI89 3994423 YP_540214.1 CDS flgE NC_007946.1 1177542 1178747 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1177542..1178747 Escherichia coli UTI89 3994424 YP_540215.1 CDS flgF NC_007946.1 1178767 1179522 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1178767..1179522 Escherichia coli UTI89 3994425 YP_540216.1 CDS flgG NC_007946.1 1179694 1180476 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1179694..1180476 Escherichia coli UTI89 3994426 YP_540217.1 CDS flgH NC_007946.1 1180514 1181227 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1180514..1181227 Escherichia coli UTI89 3994427 YP_540218.1 CDS flgI NC_007946.1 1181236 1182336 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1181236..1182336 Escherichia coli UTI89 3994428 YP_540219.2 CDS flgJ NC_007946.1 1182336 1183277 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1182336..1183277 Escherichia coli UTI89 3994429 YP_540220.1 CDS flgK NC_007946.1 1183343 1184986 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1183343..1184986 Escherichia coli UTI89 3994430 YP_540221.1 CDS flgL NC_007946.1 1184998 1185951 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1184998..1185951 Escherichia coli UTI89 3994431 YP_540222.1 CDS rne NC_007946.1 1186146 1189331 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1186146..1189331) Escherichia coli UTI89 3994432 YP_540223.1 CDS UTI89_C1210 NC_007946.1 1189412 1189786 D hypothetical protein 1189412..1189786 Escherichia coli UTI89 3994433 YP_540224.1 CDS yceC NC_007946.1 1189904 1190863 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1189904..1190863 Escherichia coli UTI89 3994434 YP_540225.1 CDS yceF NC_007946.1 1190975 1191598 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1190975..1191598) Escherichia coli UTI89 3994435 YP_540226.1 CDS yceD NC_007946.1 1191758 1192279 D hypothetical protein 1191758..1192279 Escherichia coli UTI89 3994436 YP_540227.1 CDS rpmF NC_007946.1 1192331 1192504 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1192331..1192504 Escherichia coli UTI89 3994437 YP_540228.1 CDS plsX NC_007946.1 1192585 1193655 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1192585..1193655 Escherichia coli UTI89 3994438 YP_540229.1 CDS fabH NC_007946.1 1193723 1194676 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1193723..1194676 Escherichia coli UTI89 3994439 YP_540230.1 CDS fabD NC_007946.1 1194692 1195621 D malonyl CoA-ACP transacylase 1194692..1195621 Escherichia coli UTI89 3994440 YP_540231.1 CDS fabG NC_007946.1 1195634 1196368 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1195634..1196368 Escherichia coli UTI89 3994441 YP_540232.1 CDS UTI89_C1219 NC_007946.1 1196525 1196899 R hypothetical protein complement(1196525..1196899) Escherichia coli UTI89 3993482 YP_540233.1 CDS acpP NC_007946.1 1196579 1196815 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1196579..1196815 Escherichia coli UTI89 3993483 YP_540234.1 CDS fabF NC_007946.1 1196902 1198143 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1196902..1198143 Escherichia coli UTI89 3993484 YP_540235.1 CDS pabC NC_007946.1 1198263 1199072 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1198263..1199072 Escherichia coli UTI89 3993485 YP_540237.1 CDS yceG NC_007946.1 1199075 1200097 D hypothetical protein 1199075..1200097 Escherichia coli UTI89 3993487 YP_540238.1 CDS tmk NC_007946.1 1200087 1200728 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1200087..1200728 Escherichia coli UTI89 3993488 YP_540239.1 CDS holB NC_007946.1 1200725 1201729 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1200725..1201729 Escherichia coli UTI89 3993489 YP_540240.1 CDS ycfH NC_007946.1 1201680 1202537 D metallodependent hydrolase 1201680..1202537 Escherichia coli UTI89 3993490 YP_540241.1 CDS UTI89_C1228 NC_007946.1 1202832 1204265 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1202832..1204265 Escherichia coli UTI89 3993491 YP_540242.1 CDS fhuE NC_007946.1 1204325 1206514 R ferric-rhodotorulic acid outer membrane transporter complement(1204325..1206514) Escherichia coli UTI89 3993492 YP_540243.1 CDS UTI89_C1230 NC_007946.1 1206547 1206717 R hypothetical protein complement(1206547..1206717) Escherichia coli UTI89 3993493 YP_540244.1 CDS ycfF NC_007946.1 1206848 1207207 D purine nucleoside phosphoramidase 1206848..1207207 Escherichia coli UTI89 3993494 YP_540245.1 CDS ycfL NC_007946.1 1207210 1207587 D hypothetical protein 1207210..1207587 Escherichia coli UTI89 3993495 YP_540246.1 CDS UTI89_C1233 NC_007946.1 1207598 1208242 D fibronectin-binding protein B 1207598..1208242 Escherichia coli UTI89 3993496 YP_540247.1 CDS thiK NC_007946.1 1208223 1209047 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1208223..1209047 Escherichia coli UTI89 3993497 YP_540248.1 CDS ycfO NC_007946.1 1209058 1210083 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1209058..1210083 Escherichia coli UTI89 3993498 YP_540249.1 CDS ycfP NC_007946.1 1210049 1210648 D hypothetical protein 1210049..1210648 Escherichia coli UTI89 3993499 YP_540250.1 CDS ndh NC_007946.1 1211020 1212351 D NADH dehydrogenase 1211020..1212351 Escherichia coli UTI89 3993500 YP_540251.1 CDS ycfJ NC_007946.1 1212539 1213117 D hypothetical protein 1212539..1213117 Escherichia coli UTI89 3992696 YP_540252.1 CDS ycfQ NC_007946.1 1213179 1213889 R hypothetical protein complement(1213179..1213889) Escherichia coli UTI89 3992697 YP_540253.1 CDS ycfR NC_007946.1 1214052 1214309 D hypothetical protein 1214052..1214309 Escherichia coli UTI89 3992698 YP_540254.1 CDS ycfS NC_007946.1 1214391 1215353 R hypothetical protein complement(1214391..1215353) Escherichia coli UTI89 3992699 YP_540255.1 CDS mfd NC_007946.1 1215498 1219007 R transcription-repair coupling factor complement(1215498..1219007) Escherichia coli UTI89 3992700 YP_540256.1 CDS ycfT NC_007946.1 1219072 1220145 R hypothetical protein complement(1219072..1220145) Escherichia coli UTI89 3992701 YP_540257.1 CDS ycfU NC_007946.1 1220407 1221606 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1220407..1221606 Escherichia coli UTI89 3992702 YP_540258.1 CDS lolD NC_007946.1 1221599 1222300 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1221599..1222300 Escherichia coli UTI89 3992703 YP_540259.1 CDS lolE NC_007946.1 1222300 1223544 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1222300..1223544 Escherichia coli UTI89 3992704 YP_540260.1 CDS ycfX NC_007946.1 1223573 1224484 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1223573..1224484 Escherichia coli UTI89 3992705 YP_540261.1 CDS cobB NC_007946.1 1224500 1225321 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1224500..1225321 Escherichia coli UTI89 3992706 YP_540262.1 CDS ycfZ NC_007946.1 1225459 1226247 R hypothetical protein complement(1225459..1226247) Escherichia coli UTI89 3992707 YP_540263.1 CDS ymfA NC_007946.1 1226244 1226747 R hypothetical protein complement(1226244..1226747) Escherichia coli UTI89 3992708 YP_540264.1 CDS potD NC_007946.1 1226763 1227809 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein complement(1226763..1227809) Escherichia coli UTI89 3992709 YP_540265.1 CDS potC NC_007946.1 1227806 1228600 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1227806..1228600) Escherichia coli UTI89 3992710 YP_540266.1 CDS potB NC_007946.1 1228597 1229454 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1228597..1229454) Escherichia coli UTI89 3992711 YP_540267.1 CDS potA NC_007946.1 1229438 1230574 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1229438..1230574) Escherichia coli UTI89 3992712 YP_540268.1 CDS UTI89_C1255 NC_007946.1 1230553 1230804 R hypothetical protein complement(1230553..1230804) Escherichia coli UTI89 3992713 YP_540269.1 CDS pepT NC_007946.1 1230824 1232050 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1230824..1232050 Escherichia coli UTI89 3992714 YP_540270.1 CDS UTI89_C1257 NC_007946.1 1232099 1233229 R hypothetical protein complement(1232099..1233229) Escherichia coli UTI89 3992715 YP_540271.1 CDS phoQ NC_007946.1 1233296 1234756 R sensor protein PhoQ complement(1233296..1234756) Escherichia coli UTI89 3993600 YP_540272.1 CDS phoP NC_007946.1 1234756 1235427 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1234756..1235427) Escherichia coli UTI89 3993601 YP_540273.1 CDS purB NC_007946.1 1235596 1236966 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1235596..1236966) Escherichia coli UTI89 3993602 YP_540274.1 CDS ycfC NC_007946.1 1236970 1237617 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1236970..1237617) Escherichia coli UTI89 3993603 YP_540275.1 CDS mnmA NC_007946.1 1237647 1238798 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1237647..1238798) Escherichia coli UTI89 3993604 YP_540276.1 CDS ymfB NC_007946.1 1238807 1239268 R NUDIX family hydrolase complement(1238807..1239268) Escherichia coli UTI89 3993605 YP_540277.2 CDS rluE NC_007946.1 1239278 1239901 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1239278..1239901) Escherichia coli UTI89 3993606 YP_540278.1 CDS UTI89_C1265 NC_007946.1 1240019 1241200 R hypothetical protein complement(1240019..1241200) Escherichia coli UTI89 3993607 YP_540279.1 CDS icdA NC_007946.1 1240103 1241353 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1240103..1241353 Escherichia coli UTI89 3993608 YP_540280.1 CDS UTI89_C1267 NC_007946.1 1241467 1242609 R prophage lambda integrase complement(1241467..1242609) Escherichia coli UTI89 3993609 YP_540281.1 CDS UTI89_C1268 NC_007946.1 1242599 1242835 R excisionase complement(1242599..1242835) Escherichia coli UTI89 3993610 YP_540282.1 CDS UTI89_C1269 NC_007946.1 1242975 1243214 R hypothetical protein complement(1242975..1243214) Escherichia coli UTI89 3993611 YP_540283.1 CDS UTI89_C1270 NC_007946.1 1243132 1243596 D hypothetical protein 1243132..1243596 Escherichia coli UTI89 3993612 YP_540284.1 CDS UTI89_C1271 NC_007946.1 1243198 1243527 R hypothetical protein complement(1243198..1243527) Escherichia coli UTI89 3993613 YP_540285.1 CDS UTI89_C1272 NC_007946.1 1243524 1243745 R C4-type zinc finger protein complement(1243524..1243745) Escherichia coli UTI89 3993614 YP_540286.1 CDS UTI89_C1273 NC_007946.1 1244132 1244323 R hypothetical protein complement(1244132..1244323) Escherichia coli UTI89 3993615 YP_540287.1 CDS UTI89_C1274 NC_007946.1 1244275 1244601 D hypothetical protein 1244275..1244601 Escherichia coli UTI89 3993616 YP_540288.1 CDS UTI89_C1275 NC_007946.1 1244475 1245155 R prophage CP-933K exonuclease complement(1244475..1245155) Escherichia coli UTI89 3993617 YP_540289.1 CDS bet NC_007946.1 1245152 1245937 R recombination protein Bet of prophage complement(1245152..1245937) Escherichia coli UTI89 3993618 YP_540290.1 CDS gamW NC_007946.1 1245943 1246239 R host-nuclease inhibitor protein Gam of bacteriphage complement(1245943..1246239) Escherichia coli UTI89 3991421 YP_540291.1 CDS UTI89_C1278 NC_007946.1 1246208 1246360 R hypothetical protein complement(1246208..1246360) Escherichia coli UTI89 3991422 YP_540292.1 CDS kil1 NC_007946.1 1246315 1246584 R Kil protein complement(1246315..1246584) Escherichia coli UTI89 3991423 YP_540293.1 CDS UTI89_C1280 NC_007946.1 1246427 1246591 R lambda regulatory protein CIII complement(1246427..1246591) Escherichia coli UTI89 3991424 YP_540294.1 CDS UTI89_C1281 NC_007946.1 1246664 1247032 R bacteriophage lambda single-stranded DNA binding protein complement(1246664..1247032) Escherichia coli UTI89 3991425 YP_540295.1 CDS UTI89_C1282 NC_007946.1 1247215 1247415 R lambda ant-restriction protein complement(1247215..1247415) Escherichia coli UTI89 3991426 YP_540296.1 CDS UTI89_C1283 NC_007946.1 1247629 1248210 D superinfection exclusion protein B of prophage 1247629..1248210 Escherichia coli UTI89 3991427 YP_540297.1 CDS UTI89_C1284 NC_007946.1 1248227 1248571 R N protein complement(1248227..1248571) Escherichia coli UTI89 3991428 YP_540298.1 CDS UTI89_C1285 NC_007946.1 1248477 1248659 R hypothetical protein complement(1248477..1248659) Escherichia coli UTI89 3991429 YP_540299.1 CDS UTI89_C1286 NC_007946.1 1248936 1249688 R hypothetical protein complement(1248936..1249688) Escherichia coli UTI89 3991430 YP_540300.1 CDS UTI89_C1287 NC_007946.1 1249685 1250242 R hypothetical protein complement(1249685..1250242) Escherichia coli UTI89 3991431 YP_540301.1 CDS UTI89_C1288 NC_007946.1 1250282 1250935 R CI repressor of bacteriophage complement(1250282..1250935) Escherichia coli UTI89 3991432 YP_540302.1 CDS UTI89_C1289 NC_007946.1 1251410 1251706 D bacteriophage regulatory protein CII 1251410..1251706 Escherichia coli UTI89 3991433 YP_540303.1 CDS UTI89_C1290 NC_007946.1 1251739 1252638 D bacteriophage replication protein O 1251739..1252638 Escherichia coli UTI89 3991434 YP_540304.1 CDS UTI89_C1291 NC_007946.1 1252635 1253336 D bacteriophage replication protein P 1252635..1253336 Escherichia coli UTI89 3991435 YP_540305.1 CDS UTI89_C1292 NC_007946.1 1253333 1253623 D prophage exclusion protein Ren 1253333..1253623 Escherichia coli UTI89 3991436 YP_540306.1 CDS ninB1 NC_007946.1 1253697 1254137 D NinB protein encoded within prophage 1253697..1254137 Escherichia coli UTI89 3991437 YP_540307.1 CDS UTI89_C1294 NC_007946.1 1254104 1254661 D DNA N-6-adenine-methyltransferase of bacteriophage 1254104..1254661 Escherichia coli UTI89 3991438 YP_540308.1 CDS ninE1 NC_007946.1 1254658 1254834 D NinE protein (phage 82- and lambda-like) proteins 1254658..1254834 Escherichia coli UTI89 3991439 YP_540309.1 CDS UTI89_C1296 NC_007946.1 1254837 1255178 D hypothetical protein 1254837..1255178 Escherichia coli UTI89 3991440 YP_540310.1 CDS UTI89_C1297 NC_007946.1 1255171 1255365 D hypothetical protein 1255171..1255365 Escherichia coli UTI89 3989959 YP_540311.1 CDS rusA NC_007946.1 1255385 1255747 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1255385..1255747 Escherichia coli UTI89 3989960 YP_540312.1 CDS UTI89_C1299 NC_007946.1 1255744 1255884 D hypothetical protein 1255744..1255884 Escherichia coli UTI89 3989961 YP_540313.1 CDS ybcQ1 NC_007946.1 1255955 1256353 D lambdoid prophage DLP12 antitermination protein Q-like protein 1255955..1256353 Escherichia coli UTI89 3989962 YP_540314.1 CDS nmpC NC_007946.1 1256542 1257684 R porin complement(1256542..1257684) Escherichia coli UTI89 3989963 YP_540315.1 CDS ybcR1 NC_007946.1 1258213 1258428 D hypothetical protein 1258213..1258428 Escherichia coli UTI89 3989964 YP_540316.1 CDS ybcS1 NC_007946.1 1258428 1258925 D lysozyme from lambdoid prophage DLP12 1258428..1258925 Escherichia coli UTI89 3989965 YP_540317.1 CDS UTI89_C1304 NC_007946.1 1258910 1259383 D Rz endopeptidase from lambdoid prophage DLP12 1258910..1259383 Escherichia coli UTI89 3989966 YP_540318.1 CDS ybcU NC_007946.1 1259415 1259756 R lambdoid prophage DLP12 Bor-like protein complement(1259415..1259756) Escherichia coli UTI89 3989967 YP_540319.1 CDS UTI89_C1306 NC_007946.1 1260135 1260515 D prophage TonB-like membrane protein 1260135..1260515 Escherichia coli UTI89 3989968 YP_540320.1 CDS UTI89_C1307 NC_007946.1 1260163 1260315 R hypothetical protein complement(1260163..1260315) Escherichia coli UTI89 3989969 YP_540321.1 CDS UTI89_C1308 NC_007946.1 1260638 1260991 R hypothetical protein complement(1260638..1260991) Escherichia coli UTI89 3989970 YP_540322.1 CDS UTI89_C1309 NC_007946.1 1260722 1260904 D hypothetical protein 1260722..1260904 Escherichia coli UTI89 3989971 YP_540323.1 CDS UTI89_C1310 NC_007946.1 1261134 1261478 D hypothetical protein 1261134..1261478 Escherichia coli UTI89 3989972 YP_540324.1 CDS nohA1 NC_007946.1 1261468 1262016 D Qin prophage packaging protein NU1-like protein 1261468..1262016 Escherichia coli UTI89 3989973 YP_540325.1 CDS UTI89_C1312 NC_007946.1 1261964 1263916 D prophage DNA packaging protein terminase large subunit 1261964..1263916 Escherichia coli UTI89 3989974 YP_540326.1 CDS UTI89_C1313 NC_007946.1 1263900 1264106 D prophage DNA packaging protein 1263900..1264106 Escherichia coli UTI89 3989975 YP_540327.1 CDS UTI89_C1314 NC_007946.1 1264103 1265695 D prophage capsid protein 1264103..1265695 Escherichia coli UTI89 3989976 YP_540328.1 CDS UTI89_C1315 NC_007946.1 1265685 1267190 D bacteriophage head-tail preconnector protein gp5 1265685..1267190 Escherichia coli UTI89 3989977 YP_540329.1 CDS UTI89_C1316 NC_007946.1 1267227 1267574 D bacteriophage capsid protein small subunit 1267227..1267574 Escherichia coli UTI89 3992450 YP_540330.1 CDS UTI89_C1317 NC_007946.1 1267632 1268660 D prophage capsid protein gp7 1267632..1268660 Escherichia coli UTI89 3992451 YP_540331.1 CDS UTI89_C1318 NC_007946.1 1268664 1269086 D hypothetical protein 1268664..1269086 Escherichia coli UTI89 3992452 YP_540332.1 CDS UTI89_C1319 NC_007946.1 1269058 1269432 D prophage head-tail joining protein 1269058..1269432 Escherichia coli UTI89 3992453 YP_540333.1 CDS UTI89_C1320 NC_007946.1 1269444 1270022 D prophage tail fiber component Z 1269444..1270022 Escherichia coli UTI89 3992454 YP_540334.1 CDS UTI89_C1321 NC_007946.1 1270019 1270414 D prophage tail component 1270019..1270414 Escherichia coli UTI89 3992455 YP_540335.1 CDS UTI89_C1322 NC_007946.1 1270392 1271162 D tail component of prophage CP-933X 1270392..1271162 Escherichia coli UTI89 3992456 YP_540336.1 CDS UTI89_C1323 NC_007946.1 1271178 1271600 D prophage tail component 1271178..1271600 Escherichia coli UTI89 3992457 YP_540337.1 CDS UTI89_C1324 NC_007946.1 1271582 1272016 D prophage tail component 1271582..1272016 Escherichia coli UTI89 3992458 YP_540338.1 CDS UTI89_C1325 NC_007946.1 1272009 1274570 D prophage tail component 1272009..1274570 Escherichia coli UTI89 3992459 YP_540339.1 CDS UTI89_C1326 NC_007946.1 1274567 1274896 D minor tail protein 1274567..1274896 Escherichia coli UTI89 3992460 YP_540340.1 CDS UTI89_C1327 NC_007946.1 1274800 1275450 R hypothetical protein complement(1274800..1275450) Escherichia coli UTI89 3992461 YP_540341.1 CDS UTI89_C1328 NC_007946.1 1274896 1275594 D prophage tail component 1274896..1275594 Escherichia coli UTI89 3992462 YP_540342.1 CDS UTI89_C1329 NC_007946.1 1275600 1276343 D prophage tail component 1275600..1276343 Escherichia coli UTI89 3992463 YP_540343.1 CDS UTI89_C1330 NC_007946.1 1276280 1276912 D prophage tail component 1276280..1276912 Escherichia coli UTI89 3992464 YP_540344.1 CDS UTI89_C1331 NC_007946.1 1276973 1280455 D prophage tail component 1276973..1280455 Escherichia coli UTI89 3992465 YP_540345.1 CDS UTI89_C1332 NC_007946.1 1280508 1282574 D hypothetical protein 1280508..1282574 Escherichia coli UTI89 3992466 YP_540346.1 CDS UTI89_C1333 NC_007946.1 1282571 1282849 D hypothetical protein 1282571..1282849 Escherichia coli UTI89 3992467 YP_540347.1 CDS UTI89_C1334 NC_007946.1 1282862 1283155 D hypothetical protein 1282862..1283155 Escherichia coli UTI89 3992468 YP_540348.1 CDS UTI89_C1335 NC_007946.1 1282877 1283317 R hypothetical protein complement(1282877..1283317) Escherichia coli UTI89 3992469 YP_540349.1 CDS sitD NC_007946.1 1283247 1284104 R SitD protein complement(1283247..1284104) Escherichia coli UTI89 3990423 YP_540350.1 CDS sitC NC_007946.1 1284101 1284958 R SitC protein complement(1284101..1284958) Escherichia coli UTI89 3990424 YP_540351.1 CDS sitB NC_007946.1 1284955 1285782 R SitB protein complement(1284955..1285782) Escherichia coli UTI89 3990425 YP_540352.1 CDS sitA NC_007946.1 1285782 1286696 R iron transport protein, periplasmic-binding protein SitA complement(1285782..1286696) Escherichia coli UTI89 3990426 YP_540353.1 CDS UTI89_C1340 NC_007946.1 1286975 1287259 D hypothetical protein 1286975..1287259 Escherichia coli UTI89 3990427 YP_540354.1 CDS UTI89_C1341 NC_007946.1 1287383 1288153 D hypothetical protein 1287383..1288153 Escherichia coli UTI89 3990428 YP_540355.1 CDS UTI89_C1342 NC_007946.1 1288625 1288777 D isocitrate dehydrogenase 1288625..1288777 Escherichia coli UTI89 3990429 YP_540356.1 CDS ycgX NC_007946.1 1289039 1289443 R hypothetical protein complement(1289039..1289443) Escherichia coli UTI89 3990430 YP_540357.1 CDS ycgE NC_007946.1 1289664 1290395 R transcriptional regulator YcgE complement(1289664..1290395) Escherichia coli UTI89 3990431 YP_540358.1 CDS UTI89_C1345 NC_007946.1 1290305 1290457 R hypothetical protein complement(1290305..1290457) Escherichia coli UTI89 3990432 YP_540359.1 CDS ycgF NC_007946.1 1290600 1291889 R hypothetical protein complement(1290600..1291889) Escherichia coli UTI89 3990433 YP_540360.1 CDS ycgZ NC_007946.1 1292125 1292361 D hypothetical protein 1292125..1292361 Escherichia coli UTI89 3990434 YP_540361.1 CDS UTI89_C1348 NC_007946.1 1292338 1292511 R hypothetical protein complement(1292338..1292511) Escherichia coli UTI89 3990435 YP_540362.1 CDS ymgA NC_007946.1 1292404 1292676 D hypothetical protein 1292404..1292676 Escherichia coli UTI89 3990436 YP_540363.1 CDS UTI89_C1350 NC_007946.1 1292715 1293218 R hypothetical protein complement(1292715..1293218) Escherichia coli UTI89 3990437 YP_540364.1 CDS UTI89_C1351 NC_007946.1 1293229 1293441 R hypothetical protein complement(1293229..1293441) Escherichia coli UTI89 3990438 YP_540365.1 CDS UTI89_C1352 NC_007946.1 1293507 1293761 D hypothetical protein 1293507..1293761 Escherichia coli UTI89 3990439 YP_540366.1 CDS UTI89_C1353 NC_007946.1 1295151 1295678 D hypothetical protein 1295151..1295678 Escherichia coli UTI89 3990440 YP_540367.1 CDS ymgD NC_007946.1 1295736 1296071 R hypothetical protein complement(1295736..1296071) Escherichia coli UTI89 3990441 YP_540368.1 CDS UTI89_C1355 NC_007946.1 1296075 1296419 R hypothetical protein complement(1296075..1296419) Escherichia coli UTI89 3989803 YP_540369.1 CDS UTI89_C1356 NC_007946.1 1296421 1296594 R hypothetical protein complement(1296421..1296594) Escherichia coli UTI89 3989804 YP_540370.1 CDS UTI89_C1357 NC_007946.1 1297012 1297338 D hypothetical protein 1297012..1297338 Escherichia coli UTI89 3989805 YP_540371.1 CDS UTI89_C1358 NC_007946.1 1297384 1297569 D hypothetical protein 1297384..1297569 Escherichia coli UTI89 3989806 YP_540372.1 CDS minE NC_007946.1 1297711 1297977 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1297711..1297977) Escherichia coli UTI89 3989807 YP_540373.1 CDS minD NC_007946.1 1297981 1298793 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1297981..1298793) Escherichia coli UTI89 3989808 YP_540374.2 CDS minC NC_007946.1 1298817 1299512 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1298817..1299512) Escherichia coli UTI89 3989809 YP_540375.1 CDS UTI89_C1362 NC_007946.1 1299652 1299879 D hypothetical protein 1299652..1299879 Escherichia coli UTI89 3989810 YP_540376.1 CDS ycgJ NC_007946.1 1300032 1300400 D hypothetical protein 1300032..1300400 Escherichia coli UTI89 3989811 YP_540377.1 CDS ycgK NC_007946.1 1300520 1300921 R protein YcgK complement(1300520..1300921) Escherichia coli UTI89 3989812 YP_540378.1 CDS ycgL NC_007946.1 1301130 1301456 D hypothetical protein 1301130..1301456 Escherichia coli UTI89 3989813 YP_540379.1 CDS ycgM NC_007946.1 1301528 1302187 D hypothetical protein 1301528..1302187 Escherichia coli UTI89 3989814 YP_540380.2 CDS ycgN NC_007946.1 1302279 1302725 D hypothetical protein 1302279..1302725 Escherichia coli UTI89 3989815 YP_540381.1 CDS UTI89_C1368 NC_007946.1 1302996 1303214 R hypothetical protein complement(1302996..1303214) Escherichia coli UTI89 3989816 YP_540382.1 CDS umuD NC_007946.1 1303519 1303938 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1303519..1303938 Escherichia coli UTI89 3989817 YP_540383.1 CDS umuC NC_007946.1 1303938 1305206 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1303938..1305206 Escherichia coli UTI89 3989818 YP_540384.1 CDS dsbB NC_007946.1 1305251 1305787 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1305251..1305787) Escherichia coli UTI89 3989819 YP_540385.1 CDS nhaB NC_007946.1 1305927 1307522 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1305927..1307522) Escherichia coli UTI89 3989820 YP_540386.1 CDS fadR NC_007946.1 1307690 1308409 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1307690..1308409 Escherichia coli UTI89 3989821 YP_540387.1 CDS ycgB NC_007946.1 1308572 1310104 R SpoVR family protein complement(1308572..1310104) Escherichia coli UTI89 3989822 YP_540388.1 CDS dadA NC_007946.1 1310428 1311732 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1310428..1311732 Escherichia coli UTI89 3994253 YP_540389.1 CDS dadX NC_007946.1 1311742 1312812 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1311742..1312812 Escherichia coli UTI89 3994254 YP_540390.1 CDS ycgO NC_007946.1 1312869 1314605 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1312869..1314605) Escherichia coli UTI89 3994255 YP_540391.1 CDS ldcA NC_007946.1 1314700 1315614 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1314700..1315614) Escherichia coli UTI89 3994256 YP_540393.1 CDS mltE NC_007946.1 1315600 1316325 D murein transglycosylase E 1315600..1316325 Escherichia coli UTI89 3994258 YP_540394.1 CDS ycgR NC_007946.1 1316327 1317061 R hypothetical protein complement(1316327..1317061) Escherichia coli UTI89 3994259 YP_540395.1 CDS ymgE NC_007946.1 1317229 1317516 D transglycosylase associated protein 1317229..1317516 Escherichia coli UTI89 3994260 YP_540396.1 CDS prrA NC_007946.1 1317566 1319557 R TonB dependent outer membrane receptor complement(1317566..1319557) Escherichia coli UTI89 3994261 YP_540397.1 CDS modD NC_007946.1 1319562 1320416 R involved in molybdenum transport; molybdenum transport protein ModD complement(1319562..1320416) Escherichia coli UTI89 3994262 YP_540398.1 CDS UTI89_C1385 NC_007946.1 1320413 1321225 R hypothetical protein complement(1320413..1321225) Escherichia coli UTI89 3994263 YP_540399.1 CDS UTI89_C1386 NC_007946.1 1321235 1321993 R iron ABC transporter ATP-binding protein complement(1321235..1321993) Escherichia coli UTI89 3994264 YP_540400.1 CDS UTI89_C1387 NC_007946.1 1321990 1322970 R iron ABC transporter permease complement(1321990..1322970) Escherichia coli UTI89 3994265 YP_540401.1 CDS UTI89_C1388 NC_007946.1 1322970 1323992 R hypothetical protein complement(1322970..1323992) Escherichia coli UTI89 3994266 YP_540402.1 CDS treA NC_007946.1 1324329 1326026 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1324329..1326026) Escherichia coli UTI89 3994267 YP_540403.1 CDS UTI89_C1390 NC_007946.1 1325971 1326186 D hypothetical protein 1325971..1326186 Escherichia coli UTI89 3994268 YP_540404.1 CDS ycgC NC_007946.1 1326345 1327769 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit M complement(1326345..1327769) Escherichia coli UTI89 3994269 YP_540405.1 CDS ycgS NC_007946.1 1327774 1328484 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1327774..1328484) Escherichia coli UTI89 3994270 YP_540406.1 CDS ycgT NC_007946.1 1328417 1329517 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1328417..1329517) Escherichia coli UTI89 3994271 YP_540407.1 CDS UTI89_C1394 NC_007946.1 1329706 1331634 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1329706..1331634 Escherichia coli UTI89 3989861 YP_540408.1 CDS UTI89_C1395 NC_007946.1 1331644 1331829 D hypothetical protein 1331644..1331829 Escherichia coli UTI89 3989862 YP_540409.1 CDS UTI89_C1396 NC_007946.1 1331672 1331902 R hypothetical protein complement(1331672..1331902) Escherichia coli UTI89 3989863 YP_540410.1 CDS ychF NC_007946.1 1332038 1333129 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1332038..1333129) Escherichia coli UTI89 3989864 YP_540411.1 CDS pth NC_007946.1 1333246 1333830 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1333246..1333830) Escherichia coli UTI89 3989865 YP_540412.1 CDS ychH NC_007946.1 1334108 1334386 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1334108..1334386 Escherichia coli UTI89 3989866 YP_540413.1 CDS ychM NC_007946.1 1334441 1336120 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1334441..1336120) Escherichia coli UTI89 3989867 YP_540414.1 CDS prsA NC_007946.1 1336245 1337258 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1336245..1337258) Escherichia coli UTI89 3989868 YP_540415.1 CDS ipk NC_007946.1 1337343 1338194 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1337343..1338194) Escherichia coli UTI89 3989869 YP_540416.1 CDS lolB NC_007946.1 1338194 1338883 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB complement(1338194..1338883) Escherichia coli UTI89 3989870 YP_540417.1 CDS hemA NC_007946.1 1338833 1340287 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1338833..1340287 Escherichia coli UTI89 3989871 YP_540418.1 CDS prfA NC_007946.1 1340329 1341411 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1340329..1341411 Escherichia coli UTI89 3989872 YP_540419.1 CDS hemK NC_007946.1 1341411 1342244 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1341411..1342244 Escherichia coli UTI89 3989873 YP_540420.1 CDS sirB2 NC_007946.1 1342241 1342633 D transcriptional regulator 1342241..1342633 Escherichia coli UTI89 3989874 YP_540421.1 CDS ychA NC_007946.1 1342637 1343446 D transcriptional regulator 1342637..1343446 Escherichia coli UTI89 3989875 YP_540422.1 CDS kdsA NC_007946.1 1343482 1344336 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1343482..1344336 Escherichia coli UTI89 3989876 YP_540423.1 CDS UTI89_C1410 NC_007946.1 1344346 1344609 D hypothetical protein 1344346..1344609 Escherichia coli UTI89 3989877 YP_540424.1 CDS chaA NC_007946.1 1344997 1346184 R calcium/sodium:proton antiporter complement(1344997..1346184) Escherichia coli UTI89 3989878 YP_540425.1 CDS UTI89_C1412 NC_007946.1 1346361 1346660 R hypothetical protein complement(1346361..1346660) Escherichia coli UTI89 3989879 YP_540426.1 CDS chaB NC_007946.1 1346367 1346597 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1346367..1346597 Escherichia coli UTI89 3989880 YP_540427.1 CDS chaC NC_007946.1 1346719 1347450 D cation transport protein ChaC 1346719..1347450 Escherichia coli UTI89 3994557 YP_540428.1 CDS ychN NC_007946.1 1347494 1347847 R hypothetical protein complement(1347494..1347847) Escherichia coli UTI89 3994558 YP_540429.1 CDS ychP NC_007946.1 1348032 1349426 D hypothetical protein 1348032..1349426 Escherichia coli UTI89 3994559 YP_540430.1 CDS narL NC_007946.1 1349427 1350143 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1349427..1350143) Escherichia coli UTI89 3994560 YP_540431.1 CDS narX NC_007946.1 1350070 1351866 R nitrate/nitrite sensor protein NarX complement(1350070..1351866) Escherichia coli UTI89 3994561 YP_540432.1 CDS UTI89_C1419 NC_007946.1 1351892 1352110 D hypothetical protein 1351892..1352110 Escherichia coli UTI89 3994562 YP_540433.1 CDS narK NC_007946.1 1352199 1353596 D nitrite extrusion protein 1352199..1353596 Escherichia coli UTI89 3994563 YP_540434.1 CDS narG NC_007946.1 1353989 1357732 D respiratory nitrate reductase 1 subunit alpha 1353989..1357732 Escherichia coli UTI89 3994564 YP_540435.1 CDS narH NC_007946.1 1357729 1359267 D respiratory nitrate reductase 1 subunit beta 1357729..1359267 Escherichia coli UTI89 3994565 YP_540436.1 CDS narJ NC_007946.1 1359264 1359974 D nitrate reductase 1 subunit delta 1359264..1359974 Escherichia coli UTI89 3994566 YP_540437.1 CDS narI NC_007946.1 1359974 1360651 D nitrate reductase 1, cytochrome b(NR) subunit gamma 1359974..1360651 Escherichia coli UTI89 3994567 YP_540438.1 CDS UTI89_C1425 NC_007946.1 1360704 1361933 R Tpn1330-like protein complement(1360704..1361933) Escherichia coli UTI89 3994568 YP_540439.1 CDS purU NC_007946.1 1362696 1363538 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1362696..1363538) Escherichia coli UTI89 3994571 YP_540440.2 CDS ychJ NC_007946.1 1363588 1364046 R hypothetical protein complement(1363588..1364046) Escherichia coli UTI89 3994572 YP_540441.1 CDS ychK NC_007946.1 1364120 1365064 D hypothetical protein 1364120..1365064 Escherichia coli UTI89 3994573 YP_540442.1 CDS rssB NC_007946.1 1365156 1366169 D response regulator of RpoS 1365156..1366169 Escherichia coli UTI89 3993252 YP_540443.1 CDS galU NC_007946.1 1366371 1367279 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1366371..1367279 Escherichia coli UTI89 3993253 YP_540444.1 CDS UTI89_C1433 NC_007946.1 1367387 1367740 D hypothetical protein 1367387..1367740 Escherichia coli UTI89 3993254 YP_540445.1 CDS hns NC_007946.1 1367423 1367836 R global DNA-binding transcriptional dual regulator H-NS complement(1367423..1367836) Escherichia coli UTI89 3993255 YP_540446.1 CDS UTI89_C1435 NC_007946.1 1367928 1368056 R hypothetical protein complement(1367928..1368056) Escherichia coli UTI89 3993256 YP_540447.1 CDS tdk NC_007946.1 1368440 1369057 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1368440..1369057 Escherichia coli UTI89 3993257 YP_540448.1 CDS UTI89_C1437 NC_007946.1 1369184 1370389 R transposase InsG for insertion sequence element IS4 complement(1369184..1370389) Escherichia coli UTI89 3993258 YP_540449.1 CDS adhE NC_007946.1 1370515 1373190 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1370515..1373190) Escherichia coli UTI89 3993259 YP_540450.1 CDS ychE NC_007946.1 1373667 1374314 D hypothetical protein 1373667..1374314 Escherichia coli UTI89 3993260 YP_540451.1 CDS UTI89_C1440 NC_007946.1 1374472 1374786 R hypothetical protein complement(1374472..1374786) Escherichia coli UTI89 3993261 YP_540452.1 CDS oppA NC_007946.1 1374980 1376683 D periplasmic oligopeptide-binding protein 1374980..1376683 Escherichia coli UTI89 3993262 YP_540453.1 CDS oppB NC_007946.1 1376769 1377689 D oligopeptide transporter permease 1376769..1377689 Escherichia coli UTI89 3993263 YP_540454.1 CDS oppC NC_007946.1 1377704 1378612 D oligopeptide transport system permease oppC 1377704..1378612 Escherichia coli UTI89 3993264 YP_540455.1 CDS oppD NC_007946.1 1378624 1379637 D oligopeptide transporter ATP-binding protein 1378624..1379637 Escherichia coli UTI89 3993265 YP_540456.1 CDS oppF NC_007946.1 1379634 1380638 D oligopeptide transport ATP-binding protein OppF 1379634..1380638 Escherichia coli UTI89 3993266 YP_540457.1 CDS yciU NC_007946.1 1380691 1381098 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1380691..1381098) Escherichia coli UTI89 3993267 YP_540458.1 CDS cls NC_007946.1 1381055 1382515 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1381055..1382515) Escherichia coli UTI89 3993268 YP_540459.1 CDS UTI89_C1448 NC_007946.1 1382547 1382831 D hypothetical protein 1382547..1382831 Escherichia coli UTI89 3993269 YP_540460.1 CDS kch NC_007946.1 1382886 1384157 R voltage-gated potassium channel complement(1382886..1384157) Escherichia coli UTI89 3993270 YP_540461.2 CDS yciI NC_007946.1 1384439 1384735 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein complement(1384439..1384735) Escherichia coli UTI89 3993271 YP_540462.1 CDS tonB NC_007946.1 1384908 1385675 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1384908..1385675 Escherichia coli UTI89 3991369 YP_540463.1 CDS UTI89_C1452 NC_007946.1 1385141 1385386 R hypothetical protein complement(1385141..1385386) Escherichia coli UTI89 3991370 YP_540464.1 CDS yciA NC_007946.1 1385715 1386113 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase complement(1385715..1386113) Escherichia coli UTI89 3991371 YP_540465.1 CDS ispZ NC_007946.1 1386219 1386758 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1386219..1386758) Escherichia coli UTI89 3991372 YP_540466.1 CDS yciC NC_007946.1 1386788 1387531 R hypothetical protein complement(1386788..1387531) Escherichia coli UTI89 3991373 YP_540467.1 CDS ompW NC_007946.1 1387809 1388525 D receptor for colicin S4; outer membrane protein W 1387809..1388525 Escherichia coli UTI89 3991374 YP_540468.1 CDS intO NC_007946.1 1388571 1389701 R prophage CP-933O integrase complement(1388571..1389701) Escherichia coli UTI89 3991375 YP_540469.1 CDS UTI89_C1458 NC_007946.1 1389679 1389927 R excisionase complement(1389679..1389927) Escherichia coli UTI89 3991376 YP_540470.1 CDS exoO NC_007946.1 1389992 1392463 R prophage CP-933O exonuclease VIII complement(1389992..1392463) Escherichia coli UTI89 3991377 YP_540471.1 CDS UTI89_C1460 NC_007946.1 1392556 1392756 R hypothetical protein complement(1392556..1392756) Escherichia coli UTI89 3991378 YP_540472.1 CDS UTI89_C1461 NC_007946.1 1392744 1393037 R regulator of cell division encoded by prophage CP-933O complement(1392744..1393037) Escherichia coli UTI89 3991379 YP_540473.1 CDS UTI89_C1462 NC_007946.1 1393043 1393198 D hypothetical protein 1393043..1393198 Escherichia coli UTI89 3991380 YP_540474.1 CDS ydfC NC_007946.1 1393498 1393719 R hypothetical protein complement(1393498..1393719) Escherichia coli UTI89 3991381 YP_540475.1 CDS ydfB NC_007946.1 1393749 1393919 R hypothetical protein complement(1393749..1393919) Escherichia coli UTI89 3991382 YP_540476.1 CDS ydfA NC_007946.1 1393879 1394115 R hypothetical protein complement(1393879..1394115) Escherichia coli UTI89 3991383 YP_540477.1 CDS UTI89_C1466 NC_007946.1 1394327 1394965 R prophage CP-933O repressor protein complement(1394327..1394965) Escherichia coli UTI89 3991384 YP_540478.1 CDS UTI89_C1467 NC_007946.1 1395045 1395299 D hypothetical protein 1395045..1395299 Escherichia coli UTI89 3991385 YP_540479.1 CDS UTI89_C1468 NC_007946.1 1395283 1395708 D hypothetical protein 1395283..1395708 Escherichia coli UTI89 3991386 YP_540480.1 CDS UTI89_C1469 NC_007946.1 1395849 1396850 D hypothetical protein 1395849..1396850 Escherichia coli UTI89 3991387 YP_540481.1 CDS UTI89_C1470 NC_007946.1 1396891 1397313 D prophage hypothetical protein 1396891..1397313 Escherichia coli UTI89 3990257 YP_540482.1 CDS UTI89_C1471 NC_007946.1 1397376 1398467 D hypothetical protein 1397376..1398467 Escherichia coli UTI89 3990258 YP_540483.1 CDS UTI89_C1472 NC_007946.1 1398483 1399484 D hypothetical protein 1398483..1399484 Escherichia coli UTI89 3990259 YP_540484.1 CDS UTI89_C1473 NC_007946.1 1399596 1399886 D hypothetical protein 1399596..1399886 Escherichia coli UTI89 3990260 YP_540485.1 CDS UTI89_C1474 NC_007946.1 1400045 1400257 D cryptic prophage CP-933M cell killing protein 1400045..1400257 Escherichia coli UTI89 3990261 YP_540486.1 CDS UTI89_C1475 NC_007946.1 1400425 1400703 D hypothetical protein 1400425..1400703 Escherichia coli UTI89 3990262 YP_540487.1 CDS UTI89_C1476 NC_007946.1 1400705 1401751 D hypothetical protein 1400705..1401751 Escherichia coli UTI89 3990263 YP_540489.1 CDS UTI89_C1478 NC_007946.1 1401764 1402138 D endodeoxyribonuclease RusA 1401764..1402138 Escherichia coli UTI89 3990265 YP_540490.1 CDS UTI89_C1479 NC_007946.1 1402135 1402956 D cryptic prophage CP-933M antitermination protein Q-like protein 1402135..1402956 Escherichia coli UTI89 3990266 YP_540491.1 CDS UTI89_C1480 NC_007946.1 1403181 1403378 D hypothetical protein 1403181..1403378 Escherichia coli UTI89 3990267 YP_540492.1 CDS UTI89_C1481 NC_007946.1 1403529 1404578 D prophage CP-933O DNA adenine methyltransferase 1403529..1404578 Escherichia coli UTI89 3990268 YP_540493.1 CDS UTI89_C1484 NC_007946.1 1405049 1405312 D hypothetical protein 1405049..1405312 Escherichia coli UTI89 3990271 YP_540494.1 CDS UTI89_C1485 NC_007946.1 1405853 1406080 D hypothetical protein 1405853..1406080 Escherichia coli UTI89 3990272 YP_540495.1 CDS UTI89_C1486 NC_007946.1 1406038 1406199 D hypothetical protein 1406038..1406199 Escherichia coli UTI89 3990273 YP_540496.1 CDS UTI89_C1487 NC_007946.1 1406244 1406564 D lambdoid prophage DLP12 lysis protein S-like protein 1406244..1406564 Escherichia coli UTI89 3990274 YP_540497.1 CDS ydfR NC_007946.1 1406569 1406913 D hypothetical protein 1406569..1406913 Escherichia coli UTI89 3994005 YP_540498.1 CDS UTI89_C1489 NC_007946.1 1406879 1407151 R hypothetical protein complement(1406879..1407151) Escherichia coli UTI89 3994006 YP_540499.1 CDS UTI89_C1490 NC_007946.1 1407257 1407790 D phage lysozyme 1407257..1407790 Escherichia coli UTI89 3994007 YP_540500.1 CDS UTI89_C1491 NC_007946.1 1407914 1408087 D hypothetical protein 1407914..1408087 Escherichia coli UTI89 3994008 YP_540501.1 CDS UTI89_C1492 NC_007946.1 1408089 1408553 D bacteriophage lambda cell lysis protein 1408089..1408553 Escherichia coli UTI89 3994009 YP_540502.1 CDS ydfO NC_007946.1 1408861 1409286 R hypothetical protein complement(1408861..1409286) Escherichia coli UTI89 3994010 YP_540503.1 CDS UTI89_C1494 NC_007946.1 1409329 1409562 R prophage hypothetical protein complement(1409329..1409562) Escherichia coli UTI89 3994011 YP_540504.1 CDS UTI89_C1495 NC_007946.1 1409710 1409868 D hypothetical protein 1409710..1409868 Escherichia coli UTI89 3994012 YP_540505.1 CDS nohA2 NC_007946.1 1409949 1410497 D prophage Qin DNA packaging protein NU1-like protein 1409949..1410497 Escherichia coli UTI89 3994013 YP_540506.1 CDS UTI89_C1497 NC_007946.1 1410445 1412397 D prophage DNA packaging protein terminase large subunit 1410445..1412397 Escherichia coli UTI89 3994014 YP_540507.1 CDS UTI89_C1498 NC_007946.1 1412381 1412587 D prophage DNA packaging protein 1412381..1412587 Escherichia coli UTI89 3994015 YP_540508.1 CDS UTI89_C1499 NC_007946.1 1412584 1414176 D prophage capsid protein 1412584..1414176 Escherichia coli UTI89 3994016 YP_540509.1 CDS UTI89_C1500 NC_007946.1 1414166 1415671 D prophage capsid assembly protein 1414166..1415671 Escherichia coli UTI89 3994017 YP_540510.1 CDS UTI89_C1501 NC_007946.1 1415708 1416055 D capsid protein small subunit 1415708..1416055 Escherichia coli UTI89 3994018 YP_540511.1 CDS UTI89_C1502 NC_007946.1 1416113 1417141 D prophage capsid protein 1416113..1417141 Escherichia coli UTI89 3994019 YP_540512.1 CDS UTI89_C1503 NC_007946.1 1417145 1417576 D hypothetical protein 1417145..1417576 Escherichia coli UTI89 3994020 YP_540513.1 CDS UTI89_C1504 NC_007946.1 1417569 1417922 D prophage head-tail joining protein 1417569..1417922 Escherichia coli UTI89 3994021 YP_540514.1 CDS UTI89_C1505 NC_007946.1 1417938 1418471 D minor tail protein 1417938..1418471 Escherichia coli UTI89 3994022 YP_540515.1 CDS UTI89_C1506 NC_007946.1 1418468 1418863 D prophage tail component 1418468..1418863 Escherichia coli UTI89 3994023 YP_540516.1 CDS UTI89_C1507 NC_007946.1 1418871 1419623 D tail fiber component V of prophage CP-933U 1418871..1419623 Escherichia coli UTI89 3990480 YP_540517.1 CDS UTI89_C1508 NC_007946.1 1419637 1420068 D prophage tail component 1419637..1420068 Escherichia coli UTI89 3990481 YP_540518.1 CDS UTI89_C1509 NC_007946.1 1420095 1420508 D tail component of prophage CP-933O 1420095..1420508 Escherichia coli UTI89 3990482 YP_540519.1 CDS UTI89_C1510 NC_007946.1 1420489 1423062 D tail component of prophage CP-933O 1420489..1423062 Escherichia coli UTI89 3990483 YP_540520.1 CDS UTI89_C1511 NC_007946.1 1423059 1423388 D minor tail protein 1423059..1423388 Escherichia coli UTI89 3990484 YP_540521.1 CDS UTI89_C1512 NC_007946.1 1423292 1424092 R hypothetical protein complement(1423292..1424092) Escherichia coli UTI89 3990485 YP_540522.1 CDS UTI89_C1513 NC_007946.1 1423388 1424086 D minor tail protein 1423388..1424086 Escherichia coli UTI89 3990486 YP_540523.1 CDS UTI89_C1514 NC_007946.1 1424049 1424834 D prophage tail fiber component K 1424049..1424834 Escherichia coli UTI89 3990487 YP_540524.1 CDS UTI89_C1515 NC_007946.1 1424732 1425373 D tail component of prophage CP-933K 1424732..1425373 Escherichia coli UTI89 3990488 YP_540525.1 CDS UTI89_C1516 NC_007946.1 1425447 1425785 D hypothetical protein 1425447..1425785 Escherichia coli UTI89 3990489 YP_540526.1 CDS UTI89_C1517 NC_007946.1 1425852 1429331 D prophage tail component 1425852..1429331 Escherichia coli UTI89 3990490 YP_540527.1 CDS UTI89_C1518 NC_007946.1 1429399 1429998 D hypothetical protein 1429399..1429998 Escherichia coli UTI89 3990491 YP_540528.1 CDS UTI89_C1519 NC_007946.1 1430150 1433257 D tail fiber protein 1430150..1433257 Escherichia coli UTI89 3990492 YP_540529.1 CDS UTI89_C1520 NC_007946.1 1430647 1431396 R hypothetical protein complement(1430647..1431396) Escherichia coli UTI89 3990493 YP_540530.1 CDS ynaC NC_007946.1 1433257 1433841 D phage-related tail fiber assembly protein G 1433257..1433841 Escherichia coli UTI89 3990494 YP_540531.1 CDS UTI89_C1522 NC_007946.1 1433896 1434561 R hypothetical protein complement(1433896..1434561) Escherichia coli UTI89 3990495 YP_540532.1 CDS ylcE NC_007946.1 1434621 1434890 D hypothetical protein 1434621..1434890 Escherichia coli UTI89 3990496 YP_540533.1 CDS UTI89_C1524 NC_007946.1 1434710 1435048 R hypothetical protein complement(1434710..1435048) Escherichia coli UTI89 3990497 YP_540534.1 CDS UTI89_C1525 NC_007946.1 1434894 1435175 D hypothetical protein 1434894..1435175 Escherichia coli UTI89 3990498 YP_540535.1 CDS yciE NC_007946.1 1435663 1436169 R hypothetical protein complement(1435663..1436169) Escherichia coli UTI89 3990499 YP_540536.1 CDS yciF NC_007946.1 1436215 1436715 R structural proteins complement(1436215..1436715) Escherichia coli UTI89 3990057 YP_540537.1 CDS yciG NC_007946.1 1436801 1437037 R hypothetical protein complement(1436801..1437037) Escherichia coli UTI89 3990058 YP_540538.1 CDS trpA NC_007946.1 1437361 1438167 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1437361..1438167) Escherichia coli UTI89 3990059 YP_540539.1 CDS trpB NC_007946.1 1438167 1439360 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1438167..1439360) Escherichia coli UTI89 3990060 YP_540540.1 CDS trpC NC_007946.1 1439372 1440730 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1439372..1440730) Escherichia coli UTI89 3990061 YP_540541.1 CDS trpD NC_007946.1 1440734 1442329 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1440734..1442329) Escherichia coli UTI89 3990062 YP_540542.1 CDS trpE NC_007946.1 1442329 1443891 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1442329..1443891) Escherichia coli UTI89 3990063 YP_540543.1 CDS trpH NC_007946.1 1444165 1445046 D hypothetical protein 1444165..1445046 Escherichia coli UTI89 3990064 YP_540544.1 CDS yciO NC_007946.1 1445007 1445663 D hypothetical protein 1445007..1445663 Escherichia coli UTI89 3990065 YP_540545.1 CDS yciQ NC_007946.1 1445688 1447586 D hypothetical protein 1445688..1447586 Escherichia coli UTI89 3990066 YP_540546.1 CDS yciL NC_007946.1 1447799 1448674 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1447799..1448674 Escherichia coli UTI89 3990067 YP_540547.1 CDS btuR NC_007946.1 1448714 1449304 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1448714..1449304) Escherichia coli UTI89 3990068 YP_540548.1 CDS yciK NC_007946.1 1449301 1450059 R short chain dehydrogenase complement(1449301..1450059) Escherichia coli UTI89 3990069 YP_540549.1 CDS sohB NC_007946.1 1450279 1451328 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1450279..1451328 Escherichia coli UTI89 3990070 YP_540550.1 CDS yciN NC_007946.1 1451364 1451615 R hypothetical protein complement(1451364..1451615) Escherichia coli UTI89 3990071 YP_540551.1 CDS UTI89_C1542 NC_007946.1 1451608 1451763 D hypothetical protein 1451608..1451763 Escherichia coli UTI89 3990072 YP_540552.1 CDS topA NC_007946.1 1451953 1454592 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1451953..1454592 Escherichia coli UTI89 3990073 YP_540553.1 CDS cysB NC_007946.1 1454802 1455776 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1454802..1455776 Escherichia coli UTI89 3990074 YP_540554.1 CDS UTI89_C1545 NC_007946.1 1456071 1456235 D hypothetical protein 1456071..1456235 Escherichia coli UTI89 3990075 YP_540555.1 CDS UTI89_C1546 NC_007946.1 1456217 1456405 D hypothetical protein 1456217..1456405 Escherichia coli UTI89 3994116 YP_540556.1 CDS acnA NC_007946.1 1456764 1459439 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1456764..1459439 Escherichia coli UTI89 3994117 YP_540557.1 CDS ribA NC_007946.1 1459503 1460156 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1459503..1460156) Escherichia coli UTI89 3994118 YP_540558.1 CDS pgpB NC_007946.1 1460263 1461027 D phosphatidylglycerophosphatase B 1460263..1461027 Escherichia coli UTI89 3994119 YP_540559.1 CDS yciS NC_007946.1 1461176 1461484 D hypothetical protein 1461176..1461484 Escherichia coli UTI89 3994120 YP_540560.1 CDS yciM NC_007946.1 1461491 1462660 D tetratricopeptide repeat protein 1461491..1462660 Escherichia coli UTI89 3994121 YP_540561.1 CDS pyrF NC_007946.1 1462851 1463588 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1462851..1463588 Escherichia coli UTI89 3994122 YP_540562.1 CDS yciH NC_007946.1 1463588 1463914 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1463588..1463914 Escherichia coli UTI89 3994123 YP_540563.1 CDS UTI89_C1554 NC_007946.1 1463938 1464090 D hypothetical protein 1463938..1464090 Escherichia coli UTI89 3994124 YP_540564.1 CDS osmB NC_007946.1 1464040 1464258 R lipoprotein complement(1464040..1464258) Escherichia coli UTI89 3994125 YP_540565.1 CDS UTI89_C1556 NC_007946.1 1464527 1465276 R DEOR-type transcriptional regulator complement(1464527..1465276) Escherichia coli UTI89 3994126 YP_540566.1 CDS UTI89_C1557 NC_007946.1 1465366 1465539 R hypothetical protein complement(1465366..1465539) Escherichia coli UTI89 3994127 YP_540567.1 CDS yciR NC_007946.1 1465687 1467672 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1465687..1467672) Escherichia coli UTI89 3994128 YP_540568.1 CDS rnb NC_007946.1 1467906 1469840 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1467906..1469840) Escherichia coli UTI89 3994129 YP_540569.1 CDS yciW NC_007946.1 1469908 1471113 R hypothetical protein complement(1469908..1471113) Escherichia coli UTI89 3994130 YP_540570.1 CDS fabI NC_007946.1 1471180 1471968 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1471180..1471968) Escherichia coli UTI89 3994131 YP_540571.1 CDS UTI89_C1562 NC_007946.1 1472347 1473012 D transcriptional repressor 1472347..1473012 Escherichia coli UTI89 3994132 YP_540572.1 CDS UTI89_C1563 NC_007946.1 1473128 1474282 D acriflavine resistance protein A 1473128..1474282 Escherichia coli UTI89 3994133 YP_540573.1 CDS UTI89_C1564 NC_007946.1 1474282 1477389 D acriflavine resistance protein B 1474282..1477389 Escherichia coli UTI89 3994134 YP_540574.1 CDS UTI89_C1565 NC_007946.1 1477393 1478766 D outer membrane channel protein 1477393..1478766 Escherichia coli UTI89 3994135 YP_540575.1 CDS UTI89_C1566 NC_007946.1 1478775 1479938 D membrane transport protein 1478775..1479938 Escherichia coli UTI89 3994588 YP_540576.1 CDS sapF NC_007946.1 1479986 1480792 R peptide transport system ATP-binding protein SapF complement(1479986..1480792) Escherichia coli UTI89 3994589 YP_540577.1 CDS sapD NC_007946.1 1480794 1481786 R peptide ABC transporter ATP-binding protein complement(1480794..1481786) Escherichia coli UTI89 3994590 YP_540578.1 CDS sapC NC_007946.1 1481786 1482676 R peptide transport system permease SapC complement(1481786..1482676) Escherichia coli UTI89 3994591 YP_540579.1 CDS sapB NC_007946.1 1482663 1483628 R peptide transport system permease SapB complement(1482663..1483628) Escherichia coli UTI89 3994592 YP_540580.1 CDS sapA NC_007946.1 1483625 1485268 R peptide transport periplasmic protein SapA complement(1483625..1485268) Escherichia coli UTI89 3994593 YP_540581.1 CDS ymjA NC_007946.1 1485581 1485826 R hypothetical protein complement(1485581..1485826) Escherichia coli UTI89 3994594 YP_540582.2 CDS pspF NC_007946.1 1486253 1487230 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1486253..1487230) Escherichia coli UTI89 3994595 YP_540583.1 CDS pspA NC_007946.1 1487396 1488064 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1487396..1488064 Escherichia coli UTI89 3994596 YP_540584.1 CDS pspB NC_007946.1 1488118 1488342 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1488118..1488342 Escherichia coli UTI89 3994597 YP_540585.1 CDS pspC NC_007946.1 1488342 1488701 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1488342..1488701 Escherichia coli UTI89 3994598 YP_540586.1 CDS pspD NC_007946.1 1488710 1488931 D peripheral inner membrane phage-shock protein 1488710..1488931 Escherichia coli UTI89 3994599 YP_540587.1 CDS pspE NC_007946.1 1489006 1489320 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1489006..1489320 Escherichia coli UTI89 3994600 YP_540588.1 CDS ycjM NC_007946.1 1489503 1491209 D sucrose phosphorylase 1489503..1491209 Escherichia coli UTI89 3994601 YP_540589.1 CDS UTI89_C1580 NC_007946.1 1491024 1491224 R hypothetical protein complement(1491024..1491224) Escherichia coli UTI89 3994602 YP_540590.1 CDS ycjN NC_007946.1 1491223 1492515 D ABC transporter periplasmic binding protein ycjN 1491223..1492515 Escherichia coli UTI89 3994603 YP_540591.1 CDS ycjO NC_007946.1 1492536 1493417 D binding-protein dependent transport protein 1492536..1493417 Escherichia coli UTI89 3994604 YP_540592.1 CDS ycjP NC_007946.1 1493404 1494246 D ABC transporter permease 1493404..1494246 Escherichia coli UTI89 3994605 YP_540593.1 CDS ycjQ NC_007946.1 1494277 1495329 D zinc-type alcohol dehydrogenase-like protein YcjQ 1494277..1495329 Escherichia coli UTI89 3994606 YP_540594.1 CDS ycjR NC_007946.1 1495339 1496136 D hypothetical protein 1495339..1496136 Escherichia coli UTI89 3994233 YP_540595.1 CDS ycjS NC_007946.1 1496146 1497201 D oxidoreductase YcjS 1496146..1497201 Escherichia coli UTI89 3994234 YP_540596.1 CDS ycjT NC_007946.1 1497198 1499465 D transport protein YcjT 1497198..1499465 Escherichia coli UTI89 3994235 YP_540597.1 CDS ycjU NC_007946.1 1499462 1500121 D beta-phosphoglucomutase 1499462..1500121 Escherichia coli UTI89 3994236 YP_540598.1 CDS ycjV NC_007946.1 1500135 1501217 D ABC transporter ATP-binding protein 1500135..1501217 Escherichia coli UTI89 3994237 YP_540599.1 CDS ompG NC_007946.1 1501211 1502167 D outer membrane protein G 1501211..1502167 Escherichia coli UTI89 3994238 YP_540600.1 CDS ycjW NC_007946.1 1502218 1503216 R transcriptional regulator YcjW complement(1502218..1503216) Escherichia coli UTI89 3994239 YP_540601.1 CDS ycjX NC_007946.1 1503300 1504769 D hypothetical protein 1503300..1504769 Escherichia coli UTI89 3994240 YP_540602.1 CDS ycjF NC_007946.1 1504766 1505827 D hypothetical protein 1504766..1505827 Escherichia coli UTI89 3994241 YP_540603.1 CDS tyrR NC_007946.1 1505948 1507516 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1505948..1507516 Escherichia coli UTI89 3994242 YP_540604.1 CDS tpx NC_007946.1 1507560 1508066 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1507560..1508066) Escherichia coli UTI89 3994243 YP_540605.1 CDS ycjG NC_007946.1 1508185 1509150 D hypothetical protein 1508185..1509150 Escherichia coli UTI89 3994244 YP_540606.1 CDS ycjI NC_007946.1 1509125 1509913 R murein peptide amidase A complement(1509125..1509913) Escherichia coli UTI89 3994245 YP_540607.1 CDS UTI89_C1598 NC_007946.1 1510144 1510782 R hypothetical protein complement(1510144..1510782) Escherichia coli UTI89 3994246 YP_540608.1 CDS UTI89_C1599 NC_007946.1 1510853 1511785 R hypothetical protein complement(1510853..1511785) Escherichia coli UTI89 3994247 YP_540609.1 CDS UTI89_C1600 NC_007946.1 1511911 1512810 D transcriptional regulator YcjZ 1511911..1512810 Escherichia coli UTI89 3994248 YP_540610.1 CDS mppA NC_007946.1 1513126 1514760 D periplasmic murein peptide-binding protein 1513126..1514760 Escherichia coli UTI89 3994249 YP_540611.1 CDS ynaI NC_007946.1 1514811 1515842 R hypothetical protein complement(1514811..1515842) Escherichia coli UTI89 3994250 YP_540612.1 CDS ynaJ NC_007946.1 1516086 1516343 D hypothetical protein 1516086..1516343 Escherichia coli UTI89 3994251 YP_540613.1 CDS ydaA NC_007946.1 1516393 1517343 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1516393..1517343) Escherichia coli UTI89 3994252 YP_540614.2 CDS fnr NC_007946.1 1517495 1518247 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1517495..1518247) Escherichia coli UTI89 3992010 YP_540615.1 CDS ogt NC_007946.1 1518442 1518957 R O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1518442..1518957) Escherichia coli UTI89 3992011 YP_540616.1 CDS UTI89_C1607 NC_007946.1 1518968 1519159 R hypothetical protein complement(1518968..1519159) Escherichia coli UTI89 3992012 YP_540617.1 CDS UTI89_C1608 NC_007946.1 1519489 1520304 R hypothetical protein complement(1519489..1520304) Escherichia coli UTI89 3992013 YP_540618.1 CDS UTI89_C1609 NC_007946.1 1520401 1521429 D secretion protein 1520401..1521429 Escherichia coli UTI89 3992014 YP_540619.1 CDS UTI89_C1610 NC_007946.1 1521426 1522940 D transporter 1521426..1522940 Escherichia coli UTI89 3992015 YP_540620.1 CDS ydaL NC_007946.1 1523135 1523698 D hypothetical protein 1523135..1523698 Escherichia coli UTI89 3992016 YP_540621.1 CDS ydaM NC_007946.1 1523719 1525011 R hypothetical protein complement(1523719..1525011) Escherichia coli UTI89 3992017 YP_540622.1 CDS zntB NC_007946.1 1525206 1526189 D zinc transporter 1525206..1526189 Escherichia coli UTI89 3992018 YP_540623.1 CDS dbpA NC_007946.1 1526667 1528040 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1526667..1528040 Escherichia coli UTI89 3992019 YP_540624.1 CDS ydaO NC_007946.1 1528169 1529104 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1528169..1529104) Escherichia coli UTI89 3992020 YP_540625.1 CDS UTI89_C1616 NC_007946.1 1529156 1529464 R hypothetical protein complement(1529156..1529464) Escherichia coli UTI89 3992021 YP_540626.1 CDS ynaF NC_007946.1 1531431 1531937 R hypothetical protein complement(1531431..1531937) Escherichia coli UTI89 3992022 YP_540627.1 CDS ompN NC_007946.1 1532006 1533139 R outer membrane protein N complement(1532006..1533139) Escherichia coli UTI89 3992023 YP_540628.1 CDS ydbK NC_007946.1 1533505 1537029 R pyruvate-flavodoxin oxidoreductase complement(1533505..1537029) Escherichia coli UTI89 3992024 YP_540629.1 CDS UTI89_C1620 NC_007946.1 1537100 1537435 R hypothetical protein complement(1537100..1537435) Escherichia coli UTI89 3992025 YP_540630.1 CDS UTI89_C1621 NC_007946.1 1537303 1537569 D hypothetical protein 1537303..1537569 Escherichia coli UTI89 3992026 YP_540631.1 CDS hslJ NC_007946.1 1537566 1538000 R heat-inducible protein complement(1537566..1538000) Escherichia coli UTI89 3992027 YP_540632.1 CDS ldhA NC_007946.1 1538099 1539088 R D-lactate dehydrogenase complement(1538099..1539088) Escherichia coli UTI89 3992028 YP_540633.1 CDS ydbH NC_007946.1 1539296 1541935 D hypothetical protein 1539296..1541935 Escherichia coli UTI89 3991853 YP_540634.1 CDS ynbE NC_007946.1 1541932 1542117 D hypothetical protein 1541932..1542117 Escherichia coli UTI89 3991854 YP_540635.1 CDS ydbL NC_007946.1 1542092 1542451 D hypothetical protein 1542092..1542451 Escherichia coli UTI89 3991855 YP_540636.1 CDS entS NC_007946.1 1542827 1551142 D EntS/YbdA MFS transporter 1542827..1551142 Escherichia coli UTI89 3991856 YP_540637.1 CDS UTI89_C1628 NC_007946.1 1551362 1552222 D oxidoreductase 1551362..1552222 Escherichia coli UTI89 3991857 YP_540638.1 CDS UTI89_C1629 NC_007946.1 1552267 1552491 R hypothetical protein complement(1552267..1552491) Escherichia coli UTI89 3991858 YP_540639.1 CDS ynbA NC_007946.1 1552521 1553126 D hypothetical protein 1552521..1553126 Escherichia coli UTI89 3991859 YP_540640.1 CDS ynbB NC_007946.1 1553126 1554022 D phosphatidate cytidiltransferase 1553126..1554022 Escherichia coli UTI89 3991860 YP_540641.1 CDS ynbC NC_007946.1 1554038 1555795 D methylase 1554038..1555795 Escherichia coli UTI89 3991861 YP_540642.1 CDS ynbD NC_007946.1 1555710 1557101 D hypothetical protein 1555710..1557101 Escherichia coli UTI89 3991862 YP_540643.1 CDS acpD NC_007946.1 1557155 1557760 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1557155..1557760) Escherichia coli UTI89 3991863 YP_540644.2 CDS hrpA NC_007946.1 1558018 1561863 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1558018..1561863 Escherichia coli UTI89 3991864 YP_540645.1 CDS ydcF NC_007946.1 1562136 1562936 D hypothetical protein 1562136..1562936 Escherichia coli UTI89 3991865 YP_540646.1 CDS aldA NC_007946.1 1563133 1564572 D NAD-linked; aldehyde dehydrogenase 1563133..1564572 Escherichia coli UTI89 3991866 YP_540647.1 CDS UTI89_C1638 NC_007946.1 1564614 1565615 R glyceraldehyde 3-phosphate dehydrogenase A complement(1564614..1565615) Escherichia coli UTI89 3991867 YP_540648.2 CDS cybB NC_007946.1 1565804 1566334 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1565804..1566334 Escherichia coli UTI89 3991868 YP_540649.1 CDS ydcA NC_007946.1 1566579 1566752 D hypothetical protein 1566579..1566752 Escherichia coli UTI89 3991869 YP_540650.1 CDS hok NC_007946.1 1566825 1567316 R hypothetical protein complement(1566825..1567316) Escherichia coli UTI89 3991870 YP_540651.1 CDS UTI89_C1642 NC_007946.1 1566910 1567380 D hypothetical protein 1566910..1567380 Escherichia coli UTI89 3991871 YP_540652.1 CDS ydcI NC_007946.1 1567418 1568482 R transcriptional regulator YdcI complement(1567418..1568482) Escherichia coli UTI89 3991872 YP_540653.1 CDS ydcJ NC_007946.1 1568558 1569901 D hypothetical protein 1568558..1569901 Escherichia coli UTI89 3991834 YP_540654.1 CDS mdoD NC_007946.1 1570126 1571781 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1570126..1571781 Escherichia coli UTI89 3991835 YP_540655.1 CDS ydcH NC_007946.1 1571915 1572145 D hypothetical protein 1571915..1572145 Escherichia coli UTI89 3991836 YP_540656.1 CDS rimL NC_007946.1 1572193 1572747 D acetylation of N-terminal serine of 30S ribosomal subunit protein L7; ribosomal-protein-L7/L12-serine acetyltransferase 1572193..1572747 Escherichia coli UTI89 3991837 YP_540657.1 CDS ydcK NC_007946.1 1572739 1573719 R hypothetical protein complement(1572739..1573719) Escherichia coli UTI89 3991838 YP_540658.1 CDS tehA NC_007946.1 1573735 1574835 D potassium-tellurite ethidium and proflavin transporter 1573735..1574835 Escherichia coli UTI89 3991839 YP_540659.1 CDS tehB NC_007946.1 1574832 1575425 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1574832..1575425 Escherichia coli UTI89 3991840 YP_540660.1 CDS UTI89_C1651 NC_007946.1 1575728 1576396 D hypothetical protein 1575728..1576396 Escherichia coli UTI89 3991841 YP_540661.1 CDS ydcO NC_007946.1 1576431 1577726 R hypothetical protein complement(1576431..1577726) Escherichia coli UTI89 3991842 YP_540662.1 CDS ydcN NC_007946.1 1577695 1578231 D hypothetical protein 1577695..1578231 Escherichia coli UTI89 3991843 YP_540663.1 CDS ydcP NC_007946.1 1578262 1580265 D protease YdcP 1578262..1580265 Escherichia coli UTI89 3991844 YP_540664.1 CDS yncJ NC_007946.1 1580357 1580587 R hypothetical protein complement(1580357..1580587) Escherichia coli UTI89 3991845 YP_540665.1 CDS UTI89_C1656 NC_007946.1 1580644 1580772 R hypothetical protein complement(1580644..1580772) Escherichia coli UTI89 3991846 YP_540666.1 CDS UTI89_C1657 NC_007946.1 1580799 1581002 D hypothetical protein 1580799..1581002 Escherichia coli UTI89 3991847 YP_540667.1 CDS ydcR NC_007946.1 1581081 1582487 D hypothetical protein 1581081..1582487 Escherichia coli UTI89 3991848 YP_540668.1 CDS ydcS NC_007946.1 1582732 1583877 D ABC transporter periplasmic binding protein ydcS 1582732..1583877 Escherichia coli UTI89 3991849 YP_540669.1 CDS ydcT NC_007946.1 1583895 1584908 D ABC transporter ATP-binding protein 1583895..1584908 Escherichia coli UTI89 3991850 YP_540670.1 CDS ydcU NC_007946.1 1584909 1585850 D ABC transporter permease 1584909..1585850 Escherichia coli UTI89 3991851 YP_540671.1 CDS UTI89_C1662 NC_007946.1 1585840 1586634 D transport system permease 1585840..1586634 Escherichia coli UTI89 3991852 YP_540672.1 CDS ydcW NC_007946.1 1586656 1588080 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1586656..1588080 Escherichia coli UTI89 3993521 YP_540673.1 CDS UTI89_C1664 NC_007946.1 1588269 1588547 R hypothetical protein complement(1588269..1588547) Escherichia coli UTI89 3993522 YP_540674.1 CDS ydcX NC_007946.1 1588392 1588640 D hypothetical protein 1588392..1588640 Escherichia coli UTI89 3993523 YP_540675.1 CDS ydcY NC_007946.1 1588726 1588959 D hypothetical protein 1588726..1588959 Escherichia coli UTI89 3993524 YP_540676.1 CDS ydcZ NC_007946.1 1588960 1589409 R hypothetical protein complement(1588960..1589409) Escherichia coli UTI89 3993525 YP_540677.1 CDS yncA NC_007946.1 1589406 1589987 R acetyltransferase YncA complement(1589406..1589987) Escherichia coli UTI89 3993526 YP_540678.1 CDS UTI89_C1669 NC_007946.1 1590131 1590367 D hypothetical protein 1590131..1590367 Escherichia coli UTI89 3993527 YP_540679.1 CDS yncD NC_007946.1 1590405 1592507 R tonB-dependent receptor YncD complement(1590405..1592507) Escherichia coli UTI89 3993528 YP_540680.1 CDS yncE NC_007946.1 1592749 1593810 D hypothetical protein 1592749..1593810 Escherichia coli UTI89 3993529 YP_540681.1 CDS ansP NC_007946.1 1593923 1595473 R L-asparagine permease complement(1593923..1595473) Escherichia coli UTI89 3993530 YP_540682.1 CDS UTI89_C1673 NC_007946.1 1595689 1595865 D transferase 1595689..1595865 Escherichia coli UTI89 3993531 YP_540683.1 CDS UTI89_C1674 NC_007946.1 1595978 1596289 D hypothetical protein 1595978..1596289 Escherichia coli UTI89 3993532 YP_540684.1 CDS UTI89_C1675 NC_007946.1 1596830 1597114 D hypothetical protein 1596830..1597114 Escherichia coli UTI89 3993533 YP_540685.1 CDS UTI89_C1676 NC_007946.1 1597133 1599538 D hypothetical protein 1597133..1599538 Escherichia coli UTI89 3993534 YP_540686.1 CDS UTI89_C1677 NC_007946.1 1599492 1600289 D hypothetical protein 1599492..1600289 Escherichia coli UTI89 3993535 YP_540687.1 CDS UTI89_C1678 NC_007946.1 1600660 1601127 D hypothetical protein 1600660..1601127 Escherichia coli UTI89 3993536 YP_540688.1 CDS UTI89_C1679 NC_007946.1 1601240 1601383 D hypothetical protein 1601240..1601383 Escherichia coli UTI89 3993537 YP_540689.1 CDS yddH NC_007946.1 1601993 1602562 R hypothetical protein complement(1601993..1602562) Escherichia coli UTI89 3993538 YP_540690.1 CDS nhoA NC_007946.1 1602737 1603582 D N-hydroxyarylamine O-acetyltransferase 1602737..1603582 Escherichia coli UTI89 3993539 YP_540691.1 CDS yddE NC_007946.1 1603678 1604571 R hypothetical protein complement(1603678..1604571) Escherichia coli UTI89 3993540 YP_540692.1 CDS narV NC_007946.1 1604651 1605331 R respiratory nitrate reductase 2 subunit gamma complement(1604651..1605331) Escherichia coli UTI89 3991165 YP_540693.1 CDS narW NC_007946.1 1605328 1606023 R cryptic nitrate reductase 2 subunit delta complement(1605328..1606023) Escherichia coli UTI89 3991166 YP_540694.1 CDS narY NC_007946.1 1606023 1607567 R cryptic nitrate reductase 2 subunit beta complement(1606023..1607567) Escherichia coli UTI89 3991167 YP_540695.1 CDS narZ NC_007946.1 1607564 1611427 R respiratory nitrate reductase 2 subunit alpha complement(1607564..1611427) Escherichia coli UTI89 3991168 YP_540696.1 CDS narU NC_007946.1 1611399 1612787 R nitrite extrusion protein 2 complement(1611399..1612787) Escherichia coli UTI89 3991169 YP_540697.1 CDS yddG NC_007946.1 1613060 1613941 R hypothetical protein complement(1613060..1613941) Escherichia coli UTI89 3991170 YP_540698.1 CDS fdnG NC_007946.1 1614173 1617220 D FdnG subunit alpha of formate dehydrogenase-N 1614173..1617220 Escherichia coli UTI89 3991171 YP_540699.1 CDS UTI89_C1690 NC_007946.1 1617197 1618138 R hypothetical protein complement(1617197..1618138) Escherichia coli UTI89 3991172 YP_540700.1 CDS fdnH NC_007946.1 1617233 1618117 D formate dehydrogenase-N subunit beta 1617233..1618117 Escherichia coli UTI89 3991173 YP_540701.1 CDS fdnI NC_007946.1 1618110 1618763 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1618110..1618763 Escherichia coli UTI89 3991174 YP_540702.1 CDS UTI89_C1693 NC_007946.1 1618966 1619238 D hypothetical protein 1618966..1619238 Escherichia coli UTI89 3991175 YP_540703.1 CDS UTI89_C1694 NC_007946.1 1618992 1619276 R hypothetical protein complement(1618992..1619276) Escherichia coli UTI89 3991176 YP_540704.1 CDS UTI89_C1695 NC_007946.1 1619276 1619548 R hypothetical protein complement(1619276..1619548) Escherichia coli UTI89 3991177 YP_540705.1 CDS adhP NC_007946.1 1619740 1620780 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1619740..1620780) Escherichia coli UTI89 3991178 YP_540706.1 CDS sfcA NC_007946.1 1620884 1622608 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1620884..1622608) Escherichia coli UTI89 3991179 YP_540707.1 CDS rpsV NC_007946.1 1622737 1622874 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1622737..1622874) Escherichia coli UTI89 3991180 YP_540708.2 CDS bdm NC_007946.1 1622976 1623191 R biofilm-dependent modulation protein complement(1622976..1623191) Escherichia coli UTI89 3991181 YP_540709.1 CDS UTI89_C1700 NC_007946.1 1623358 1623498 D hypothetical protein 1623358..1623498 Escherichia coli UTI89 3991182 YP_540710.1 CDS osmC NC_007946.1 1623536 1623967 D osmotically inducible protein OsmC 1623536..1623967 Escherichia coli UTI89 3991183 YP_540711.1 CDS UTI89_C1702 NC_007946.1 1624157 1626580 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1624157..1626580) Escherichia coli UTI89 3991441 YP_540712.1 CDS UTI89_C1703 NC_007946.1 1626581 1626799 R hypothetical protein complement(1626581..1626799) Escherichia coli UTI89 3991442 YP_540713.1 CDS UTI89_C1704 NC_007946.1 1626652 1626825 R hypothetical protein complement(1626652..1626825) Escherichia coli UTI89 3991443 YP_540714.1 CDS yddW NC_007946.1 1627123 1628442 R lipoprotein YddW complement(1627123..1628442) Escherichia coli UTI89 3991444 YP_540715.1 CDS xasA NC_007946.1 1628573 1630108 R amino acid antiporter complement(1628573..1630108) Escherichia coli UTI89 3991445 YP_540716.1 CDS gadB NC_007946.1 1630264 1631733 R glutamate decarboxylase beta complement(1630264..1631733) Escherichia coli UTI89 3991446 YP_540717.1 CDS pqqL NC_007946.1 1632025 1634820 R zinc protease PqqL complement(1632025..1634820) Escherichia coli UTI89 3991447 YP_540718.1 CDS yddB NC_007946.1 1634865 1637237 R hypothetical protein complement(1634865..1637237) Escherichia coli UTI89 3991448 YP_540719.1 CDS yddA NC_007946.1 1637275 1638960 R ABC transporter ATP-binding protein complement(1637275..1638960) Escherichia coli UTI89 3991449 YP_540720.1 CDS ydeM NC_007946.1 1639251 1640423 R hypothetical protein complement(1639251..1640423) Escherichia coli UTI89 3991450 YP_540721.1 CDS ydeN NC_007946.1 1640460 1642175 R sulfatase YdeN complement(1640460..1642175) Escherichia coli UTI89 3991451 YP_540722.1 CDS UTI89_C1713 NC_007946.1 1642544 1643305 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1642544..1643305) Escherichia coli UTI89 3991452 YP_540723.1 CDS UTI89_C1714 NC_007946.1 1643380 1643577 R hypothetical protein complement(1643380..1643577) Escherichia coli UTI89 3991453 YP_540724.1 CDS ydeP NC_007946.1 1643825 1646104 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase complement(1643825..1646104) Escherichia coli UTI89 3991454 YP_540725.1 CDS fmlD NC_007946.1 1646443 1647357 R synonym: ydeQ; Fml fimbrial adhesin FmlD complement(1646443..1647357) Escherichia coli UTI89 3991455 YP_540726.1 CDS fmlC NC_007946.1 1647682 1649232 R outer membrane usher FmlC protein complement(1647682..1649232) Escherichia coli UTI89 3991456 YP_540727.1 CDS fmlB NC_007946.1 1649274 1649984 R periplasmic chaperone FmlB protein complement(1649274..1649984) Escherichia coli UTI89 3991457 YP_540728.1 CDS fmlA NC_007946.1 1650346 1650957 R Fml fimbriae subunit complement(1650346..1650957) Escherichia coli UTI89 3991458 YP_540729.1 CDS UTI89_C1720 NC_007946.1 1651437 1651679 R hypothetical protein complement(1651437..1651679) Escherichia coli UTI89 3991459 YP_540730.1 CDS UTI89_C1721 NC_007946.1 1651685 1652467 R hypothetical protein complement(1651685..1652467) Escherichia coli UTI89 3991460 YP_540731.1 CDS UTI89_C1722 NC_007946.1 1652577 1652834 D hypothetical protein 1652577..1652834 Escherichia coli UTI89 3991571 YP_540732.1 CDS UTI89_C1723 NC_007946.1 1653155 1653403 R hypothetical protein complement(1653155..1653403) Escherichia coli UTI89 3991572 YP_540733.1 CDS UTI89_C1724 NC_007946.1 1653363 1653728 D hypothetical protein 1653363..1653728 Escherichia coli UTI89 3991573 YP_540734.1 CDS UTI89_C1725 NC_007946.1 1653886 1655130 R phage-related secreted protein complement(1653886..1655130) Escherichia coli UTI89 3991574 YP_540735.1 CDS UTI89_C1726 NC_007946.1 1655130 1656155 R phage-related membrane protein complement(1655130..1656155) Escherichia coli UTI89 3991575 YP_540736.1 CDS UTI89_C1727 NC_007946.1 1656130 1656462 D hypothetical protein 1656130..1656462 Escherichia coli UTI89 3991576 YP_540737.1 CDS UTI89_C1728 NC_007946.1 1656159 1656446 R phage-related membrane protein complement(1656159..1656446) Escherichia coli UTI89 3991577 YP_540738.1 CDS UTI89_C1729 NC_007946.1 1656459 1658171 R hypothetical protein complement(1656459..1658171) Escherichia coli UTI89 3991578 YP_540739.1 CDS UTI89_C1730 NC_007946.1 1658236 1658469 R phage-related membrane protein complement(1658236..1658469) Escherichia coli UTI89 3991579 YP_540740.1 CDS UTI89_C1731 NC_007946.1 1658504 1658755 R phage-related membrane protein complement(1658504..1658755) Escherichia coli UTI89 3991580 YP_540741.1 CDS UTI89_C1732 NC_007946.1 1658758 1659075 R hypothetical protein complement(1658758..1659075) Escherichia coli UTI89 3991581 YP_540742.1 CDS UTI89_C1733 NC_007946.1 1659087 1660139 R hypothetical protein complement(1659087..1660139) Escherichia coli UTI89 3991582 YP_540743.1 CDS UTI89_C1734 NC_007946.1 1660335 1660757 D hypothetical protein 1660335..1660757 Escherichia coli UTI89 3991583 YP_540744.1 CDS UTI89_C1735 NC_007946.1 1660857 1661279 D hypothetical protein 1660857..1661279 Escherichia coli UTI89 3991584 YP_540745.1 CDS UTI89_C1736 NC_007946.1 1661387 1662496 D hypothetical protein 1661387..1662496 Escherichia coli UTI89 3991585 YP_540746.1 CDS hipB NC_007946.1 1664002 1664286 R DNA-binding transcriptional regulator HipB complement(1664002..1664286) Escherichia coli UTI89 3991586 YP_540747.1 CDS tam NC_007946.1 1664576 1665334 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1664576..1665334 Escherichia coli UTI89 3991587 YP_540748.1 CDS yneE NC_007946.1 1665338 1666303 R hypothetical protein complement(1665338..1666303) Escherichia coli UTI89 3991588 YP_540749.1 CDS uxaB NC_007946.1 1666449 1667900 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1666449..1667900) Escherichia coli UTI89 3991589 YP_540750.1 CDS yneF NC_007946.1 1668127 1669545 R hypothetical protein complement(1668127..1669545) Escherichia coli UTI89 3991718 YP_540751.1 CDS yneG NC_007946.1 1669684 1670043 R hypothetical protein complement(1669684..1670043) Escherichia coli UTI89 3991719 YP_540752.1 CDS yneH NC_007946.1 1670043 1670969 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1670043..1670969) Escherichia coli UTI89 3991720 YP_540753.1 CDS yneI NC_007946.1 1671033 1672445 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(1671033..1672445) Escherichia coli UTI89 3991721 YP_540754.1 CDS yneJ NC_007946.1 1672522 1673403 D transcriptional regulator YneJ 1672522..1673403 Escherichia coli UTI89 3991722 YP_540755.1 CDS yneK NC_007946.1 1673481 1673600 D hypothetical protein 1673481..1673600 Escherichia coli UTI89 3991723 YP_540756.1 CDS sotB NC_007946.1 1673742 1674932 D sugar efflux transporter 1673742..1674932 Escherichia coli UTI89 3991724 YP_540757.1 CDS marC NC_007946.1 1674957 1675622 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1674957..1675622) Escherichia coli UTI89 3991725 YP_540758.1 CDS marR NC_007946.1 1675834 1676268 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1675834..1676268 Escherichia coli UTI89 3991726 YP_540759.2 CDS marA NC_007946.1 1676289 1676672 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1676289..1676672 Escherichia coli UTI89 3991727 YP_540760.1 CDS marB NC_007946.1 1676704 1676922 D hypothetical protein 1676704..1676922 Escherichia coli UTI89 3991728 YP_540761.1 CDS celA NC_007946.1 1676979 1678424 R converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase complement(1676979..1678424) Escherichia coli UTI89 3991729 YP_540762.1 CDS UTI89_C1753 NC_007946.1 1678442 1680115 R outer membrane protein YieC complement(1678442..1680115) Escherichia coli UTI89 3991730 YP_540763.1 CDS UTI89_C1754 NC_007946.1 1680170 1680484 R PTS system cellobiose-specific transporter subunit IIA complement(1680170..1680484) Escherichia coli UTI89 3991731 YP_540764.1 CDS UTI89_C1755 NC_007946.1 1680509 1681870 R hypothetical protein complement(1680509..1681870) Escherichia coli UTI89 3991732 YP_540765.1 CDS UTI89_C1756 NC_007946.1 1681946 1682257 R PTS system cellobiose-specific transporter subunit IIB complement(1681946..1682257) Escherichia coli UTI89 3991733 YP_540766.1 CDS UTI89_C1757 NC_007946.1 1682456 1683154 D hypothetical protein 1682456..1683154 Escherichia coli UTI89 3991734 YP_540767.2 CDS ydeD NC_007946.1 1683199 1684098 R O-acetylserine/cysteine export protein complement(1683199..1684098) Escherichia coli UTI89 3991735 YP_540768.1 CDS ydeF NC_007946.1 1684293 1685480 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1684293..1685480 Escherichia coli UTI89 3991736 YP_540769.1 CDS ydeH NC_007946.1 1685921 1686817 R hypothetical protein complement(1685921..1686817) Escherichia coli UTI89 3991737 YP_540770.1 CDS dcp NC_007946.1 1687319 1689430 R dipeptidyl carboxypeptidase II complement(1687319..1689430) Escherichia coli UTI89 3990612 YP_540771.1 CDS ydfG NC_007946.1 1689486 1690247 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1689486..1690247 Escherichia coli UTI89 3990613 YP_540772.1 CDS ydfH NC_007946.1 1690336 1691022 D hypothetical protein 1690336..1691022 Escherichia coli UTI89 3990614 YP_540773.1 CDS UTI89_C1764 NC_007946.1 1691157 1691429 R hypothetical protein complement(1691157..1691429) Escherichia coli UTI89 3990615 YP_540774.1 CDS ydfZ NC_007946.1 1691199 1691402 D hypothetical protein 1691199..1691402 Escherichia coli UTI89 3990616 YP_540775.1 CDS ydfI NC_007946.1 1691438 1692898 R oxidoreductase YdfI complement(1691438..1692898) Escherichia coli UTI89 3990617 YP_540776.1 CDS rspB NC_007946.1 1693399 1694442 R dehydrogenase complement(1693399..1694442) Escherichia coli UTI89 3990618 YP_540777.1 CDS rspA NC_007946.1 1694430 1695677 R starvation sensing protein RspA complement(1694430..1695677) Escherichia coli UTI89 3990619 YP_540778.1 CDS ynfA NC_007946.1 1695850 1696185 R hypothetical protein complement(1695850..1696185) Escherichia coli UTI89 3990620 YP_540779.1 CDS ynfB NC_007946.1 1696311 1696652 D hypothetical protein 1696311..1696652 Escherichia coli UTI89 3990621 YP_540780.1 CDS speG NC_007946.1 1696687 1697247 D spermidine N(1)-acetyltransferase 1696687..1697247 Escherichia coli UTI89 3990622 YP_540781.1 CDS ynfC NC_007946.1 1697250 1697996 R hypothetical protein complement(1697250..1697996) Escherichia coli UTI89 3990623 YP_540782.1 CDS ynfD NC_007946.1 1698026 1698373 D hypothetical protein 1698026..1698373 Escherichia coli UTI89 3990624 YP_540783.1 CDS ynfE NC_007946.1 1698572 1700998 D dimethyl sulfoxide reductase chain YnfE 1698572..1700998 Escherichia coli UTI89 3990625 YP_540784.1 CDS ynfF NC_007946.1 1701056 1703482 D dimethyl sulfoxide reductase chain YnfF 1701056..1703482 Escherichia coli UTI89 3990626 YP_540785.1 CDS ynfG NC_007946.1 1703493 1704110 D DmsB-like; dimethyl sulfoxide reductase-like subunit; Fe-S subunit oxidoreductase 1703493..1704110 Escherichia coli UTI89 3990627 YP_540786.1 CDS ynfH NC_007946.1 1704112 1704966 D anaerobic dimethyl sulfoxide reductase chain YnfH 1704112..1704966 Escherichia coli UTI89 3990628 YP_540787.2 CDS ynfI NC_007946.1 1705009 1705623 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1705009..1705623 Escherichia coli UTI89 3990629 YP_540788.2 CDS ynfJ NC_007946.1 1705820 1707001 D voltage-gated ClC-type chloride channel ClcB 1705820..1707001 Escherichia coli UTI89 3990630 YP_540789.1 CDS ynfK NC_007946.1 1706954 1707661 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1706954..1707661) Escherichia coli UTI89 3993946 YP_540790.1 CDS mlc NC_007946.1 1707774 1708994 R NAGC-like transcriptional regulator complement(1707774..1708994) Escherichia coli UTI89 3993947 YP_540791.1 CDS ynfL NC_007946.1 1709129 1710022 R transcriptional regulator YnfL complement(1709129..1710022) Escherichia coli UTI89 3993948 YP_540792.1 CDS ynfM NC_007946.1 1710129 1711382 D transport protein YnfM 1710129..1711382 Escherichia coli UTI89 3993949 YP_540793.1 CDS UTI89_C1784 NC_007946.1 1711780 1712115 D required for growth and survival under moderately acid conditions; acid shock protein 1711780..1712115 Escherichia coli UTI89 3993950 YP_540795.1 CDS UTI89_C1786 NC_007946.1 1712391 1713212 D hypothetical protein 1712391..1713212 Escherichia coli UTI89 3993952 YP_540796.1 CDS ydgE NC_007946.1 1713251 1713580 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1713251..1713580) Escherichia coli UTI89 3993953 YP_540797.1 CDS ydgF NC_007946.1 1713567 1713932 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1713567..1713932) Escherichia coli UTI89 3993954 YP_540798.1 CDS tqsA NC_007946.1 1714343 1715377 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 1714343..1715377 Escherichia coli UTI89 3993955 YP_540799.1 CDS pntB NC_007946.1 1715402 1716790 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1715402..1716790) Escherichia coli UTI89 3993956 YP_540800.1 CDS pntA NC_007946.1 1716801 1718387 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1716801..1718387) Escherichia coli UTI89 3993957 YP_540801.1 CDS UTI89_C1792 NC_007946.1 1718857 1719801 D hypothetical protein 1718857..1719801 Escherichia coli UTI89 3993958 YP_540802.1 CDS ydgI NC_007946.1 1719987 1721369 D arginine/ornithine antiporter 1719987..1721369 Escherichia coli UTI89 3993959 YP_540803.1 CDS ydgB NC_007946.1 1721406 1722128 D short chain dehydrogenase 1721406..1722128 Escherichia coli UTI89 3993960 YP_540804.1 CDS ydgC NC_007946.1 1722125 1722460 R hypothetical protein complement(1722125..1722460) Escherichia coli UTI89 3993961 YP_540805.1 CDS rstA NC_007946.1 1722529 1723308 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1722529..1723308 Escherichia coli UTI89 3993962 YP_540806.1 CDS rstB NC_007946.1 1723312 1724613 D sensor protein RstB 1723312..1724613 Escherichia coli UTI89 3993963 YP_540807.1 CDS tus NC_007946.1 1724677 1725618 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1724677..1725618 Escherichia coli UTI89 3993964 YP_540808.1 CDS fumC NC_007946.1 1725615 1727018 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1725615..1727018) Escherichia coli UTI89 3993965 YP_540809.1 CDS fumA NC_007946.1 1727161 1728807 R fumarase A complement(1727161..1728807) Escherichia coli UTI89 3992854 YP_540810.1 CDS manA NC_007946.1 1729006 1730181 D mannose-6-phosphate isomerase 1729006..1730181 Escherichia coli UTI89 3992855 YP_540811.1 CDS ydgA NC_007946.1 1730282 1731790 D hypothetical protein 1730282..1731790 Escherichia coli UTI89 3992856 YP_540812.1 CDS uidC NC_007946.1 1731835 1733100 R porin complement(1731835..1733100) Escherichia coli UTI89 3992857 YP_540813.1 CDS uidB NC_007946.1 1733139 1734512 R glucuronide transporter complement(1733139..1734512) Escherichia coli UTI89 3992858 YP_540814.1 CDS uidA NC_007946.1 1734509 1736320 R beta-D-glucuronidase complement(1734509..1736320) Escherichia coli UTI89 3992859 YP_540815.1 CDS uidR NC_007946.1 1736710 1737300 R repressor for uid operon complement(1736710..1737300) Escherichia coli UTI89 3992860 YP_540816.1 CDS hdhA NC_007946.1 1737529 1738296 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1737529..1738296) Escherichia coli UTI89 3992861 YP_540817.1 CDS malI NC_007946.1 1738408 1739436 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1738408..1739436) Escherichia coli UTI89 3992862 YP_540818.1 CDS malX NC_007946.1 1739407 1741203 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1739407..1741203 Escherichia coli UTI89 3992863 YP_540819.1 CDS malY NC_007946.1 1741213 1742385 D maltose regulon modulator 1741213..1742385 Escherichia coli UTI89 3992864 YP_540820.1 CDS add NC_007946.1 1742489 1743490 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1742489..1743490 Escherichia coli UTI89 3992865 YP_540821.2 CDS ydgJ NC_007946.1 1743526 1744566 R oxidoreductase complement(1743526..1744566) Escherichia coli UTI89 3992866 YP_540822.1 CDS UTI89_C1813 NC_007946.1 1744809 1744934 D beta-lactam resistance protein 1744809..1744934 Escherichia coli UTI89 3992867 YP_540823.1 CDS UTI89_C1814 NC_007946.1 1745023 1745286 D hypothetical protein 1745023..1745286 Escherichia coli UTI89 3992868 YP_540824.1 CDS ydgT NC_007946.1 1745207 1745422 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1745207..1745422 Escherichia coli UTI89 3992869 YP_540825.1 CDS ydgK NC_007946.1 1745484 1745948 D hypothetical protein 1745484..1745948 Escherichia coli UTI89 3992870 YP_540826.1 CDS rnfA NC_007946.1 1746025 1746606 D Na(+)-translocating NADH-quinone reductase subunit E 1746025..1746606 Escherichia coli UTI89 3992871 YP_540827.1 CDS rnfB NC_007946.1 1746606 1747184 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1746606..1747184 Escherichia coli UTI89 3992872 YP_540828.1 CDS rnfC NC_007946.1 1747177 1749303 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1747177..1749303 Escherichia coli UTI89 3992756 YP_540829.1 CDS rnfD NC_007946.1 1749304 1750362 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1749304..1750362 Escherichia coli UTI89 3992757 YP_540830.1 CDS rnfG NC_007946.1 1750366 1750986 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1750366..1750986 Escherichia coli UTI89 3992758 YP_540831.1 CDS ydgQ NC_007946.1 1750990 1751685 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1750990..1751685 Escherichia coli UTI89 3992759 YP_540832.1 CDS nth NC_007946.1 1751685 1752320 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1751685..1752320 Escherichia coli UTI89 3992760 YP_540833.1 CDS UTI89_C1824 NC_007946.1 1752448 1752648 D hypothetical protein 1752448..1752648 Escherichia coli UTI89 3992761 YP_540834.1 CDS tppB NC_007946.1 1752931 1754433 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1752931..1754433 Escherichia coli UTI89 3992762 YP_540835.1 CDS gst NC_007946.1 1754538 1755143 D glutathionine S-transferase 1754538..1755143 Escherichia coli UTI89 3992763 YP_540836.1 CDS pdxY NC_007946.1 1755187 1756050 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1755187..1756050) Escherichia coli UTI89 3992764 YP_540837.1 CDS tyrS NC_007946.1 1756109 1757395 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1756109..1757395) Escherichia coli UTI89 3992765 YP_540838.1 CDS pdxH NC_007946.1 1757512 1758168 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1757512..1758168) Escherichia coli UTI89 3992766 YP_540839.1 CDS ydhA NC_007946.1 1758227 1758556 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1758227..1758556) Escherichia coli UTI89 3992767 YP_540840.1 CDS anmK NC_007946.1 1758654 1759763 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1758654..1759763) Escherichia coli UTI89 3992768 YP_540841.1 CDS slyB NC_007946.1 1760037 1760504 D outer membrane lipoprotein SlyB 1760037..1760504 Escherichia coli UTI89 3992769 YP_540842.1 CDS slyA NC_007946.1 1760551 1760991 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1760551..1760991) Escherichia coli UTI89 3992770 YP_540843.1 CDS ydhI NC_007946.1 1761186 1761422 D hypothetical protein 1761186..1761422 Escherichia coli UTI89 3992771 YP_540844.1 CDS ydhJ NC_007946.1 1761383 1762282 D hypothetical protein 1761383..1762282 Escherichia coli UTI89 3992772 YP_540845.1 CDS ydhK NC_007946.1 1762282 1764294 D hypothetical protein 1762282..1764294 Escherichia coli UTI89 3992773 YP_540846.1 CDS sodC NC_007946.1 1764295 1764867 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1764295..1764867) Escherichia coli UTI89 3992774 YP_540847.1 CDS ydhF NC_007946.1 1764897 1765793 R oxidoreductase YdhF complement(1764897..1765793) Escherichia coli UTI89 3992775 YP_540848.1 CDS ydhL NC_007946.1 1765842 1766219 R hypothetical protein complement(1765842..1766219) Escherichia coli UTI89 3991648 YP_540849.1 CDS ydhM NC_007946.1 1766184 1766783 D hypothetical protein 1766184..1766783 Escherichia coli UTI89 3991649 YP_540850.1 CDS nemA NC_007946.1 1766820 1767917 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1766820..1767917 Escherichia coli UTI89 3991650 YP_540851.1 CDS gloA NC_007946.1 1767998 1768405 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1767998..1768405 Escherichia coli UTI89 3991651 YP_540852.1 CDS rnt NC_007946.1 1768508 1769155 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1768508..1769155 Escherichia coli UTI89 3991652 YP_540853.1 CDS UTI89_C1844 NC_007946.1 1769248 1769391 D hypothetical protein 1769248..1769391 Escherichia coli UTI89 3991653 YP_540854.1 CDS ydhD NC_007946.1 1769527 1769874 R hypothetical protein complement(1769527..1769874) Escherichia coli UTI89 3991654 YP_540855.1 CDS ydhO NC_007946.1 1770209 1771024 D lipoprotein 1770209..1771024 Escherichia coli UTI89 3991655 YP_540856.1 CDS sodB NC_007946.1 1771152 1771733 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1771152..1771733 Escherichia coli UTI89 3991656 YP_540857.1 CDS ydhP NC_007946.1 1771879 1773048 R transport protein complement(1771879..1773048) Escherichia coli UTI89 3991657 YP_540858.1 CDS purR NC_007946.1 1773602 1774627 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1773602..1774627 Escherichia coli UTI89 3991658 YP_540859.1 CDS ydhB NC_007946.1 1774624 1775556 R DNA-binding transcriptional regulator complement(1774624..1775556) Escherichia coli UTI89 3991659 YP_540860.1 CDS ydhC NC_007946.1 1775669 1776880 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1775669..1776880 Escherichia coli UTI89 3991660 YP_540861.1 CDS cfa NC_007946.1 1777171 1778319 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1777171..1778319 Escherichia coli UTI89 3991661 YP_540862.1 CDS ribC NC_007946.1 1778359 1779000 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1778359..1779000) Escherichia coli UTI89 3991662 YP_540863.1 CDS ydhE NC_007946.1 1779215 1780588 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1779215..1780588 Escherichia coli UTI89 3991663 YP_540864.1 CDS ydhQ NC_007946.1 1780629 1781885 R hypothetical protein complement(1780629..1781885) Escherichia coli UTI89 3991664 YP_540866.1 CDS UTI89_C1859 NC_007946.1 1782459 1782764 D hypothetical protein 1782459..1782764 Escherichia coli UTI89 3993909 YP_540867.1 CDS ydhS NC_007946.1 1782890 1784494 D hypothetical protein 1782890..1784494 Escherichia coli UTI89 3993910 YP_540868.1 CDS ydhT NC_007946.1 1784506 1785318 R hypothetical protein complement(1784506..1785318) Escherichia coli UTI89 3993911 YP_540869.1 CDS ydhU NC_007946.1 1785322 1786107 R hypothetical protein complement(1785322..1786107) Escherichia coli UTI89 3993912 YP_540870.1 CDS UTI89_C1863 NC_007946.1 1786104 1786823 R oxidoreductase Fe-S subunit complement(1786104..1786823) Escherichia coli UTI89 3993913 YP_540871.1 CDS ydhW NC_007946.1 1786836 1787483 R hypothetical protein complement(1786836..1787483) Escherichia coli UTI89 3993914 YP_540872.2 CDS ydhV NC_007946.1 1787487 1789589 R oxidoreductase complement(1787487..1789589) Escherichia coli UTI89 3993915 YP_540873.1 CDS ydhY NC_007946.1 1789610 1790236 R hypothetical protein complement(1789610..1790236) Escherichia coli UTI89 3993916 YP_540874.1 CDS ydhZ NC_007946.1 1790692 1790901 R hypothetical protein complement(1790692..1790901) Escherichia coli UTI89 3993917 YP_540875.1 CDS pykF NC_007946.1 1791242 1792870 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1791242..1792870 Escherichia coli UTI89 3993918 YP_540876.1 CDS lpp NC_007946.1 1793181 1793417 D murein lipoprotein 1793181..1793417 Escherichia coli UTI89 3993919 YP_540877.1 CDS ynhG NC_007946.1 1793480 1794484 R hypothetical protein complement(1793480..1794484) Escherichia coli UTI89 3993920 YP_540878.1 CDS sufE NC_007946.1 1794633 1795049 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1794633..1795049) Escherichia coli UTI89 3993921 YP_540879.1 CDS sufS NC_007946.1 1795062 1796282 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1795062..1796282) Escherichia coli UTI89 3993922 YP_540880.1 CDS sufD NC_007946.1 1796279 1797550 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase complement(1796279..1797550) Escherichia coli UTI89 3993923 YP_540881.1 CDS sufC NC_007946.1 1797525 1798271 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1797525..1798271) Escherichia coli UTI89 3993924 YP_540882.1 CDS sufB NC_007946.1 1798281 1799807 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase complement(1798281..1799807) Escherichia coli UTI89 3993925 YP_540883.1 CDS sufA NC_007946.1 1799777 1800145 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1799777..1800145) Escherichia coli UTI89 3992931 YP_540884.1 CDS ydiH NC_007946.1 1800694 1800963 R hypothetical protein complement(1800694..1800963) Escherichia coli UTI89 3992932 YP_540885.1 CDS ydiI NC_007946.1 1800982 1801392 R hypothetical protein complement(1800982..1801392) Escherichia coli UTI89 3992933 YP_540886.1 CDS ydiJ NC_007946.1 1801389 1804445 R hypothetical protein complement(1801389..1804445) Escherichia coli UTI89 3992934 YP_540887.1 CDS ydiK NC_007946.1 1804659 1805771 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; hypothetical protein 1804659..1805771 Escherichia coli UTI89 3992935 YP_540888.1 CDS ydiL NC_007946.1 1806173 1806556 D hypothetical protein 1806173..1806556 Escherichia coli UTI89 3992936 YP_540889.1 CDS ydiM NC_007946.1 1806656 1807870 D transport protein YdiM 1806656..1807870 Escherichia coli UTI89 3992937 YP_540890.1 CDS ydiN NC_007946.1 1808091 1809362 D transport protein YdiN 1808091..1809362 Escherichia coli UTI89 3992938 YP_540891.1 CDS ydiB NC_007946.1 1809374 1810240 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1809374..1810240 Escherichia coli UTI89 3992939 YP_540892.1 CDS aroD NC_007946.1 1810271 1811029 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1810271..1811029 Escherichia coli UTI89 3992940 YP_540893.1 CDS ydiF NC_007946.1 1811175 1812770 D hypothetical protein 1811175..1812770 Escherichia coli UTI89 3992941 YP_540894.2 CDS ydiO NC_007946.1 1812784 1813935 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1812784..1813935 Escherichia coli UTI89 3992942 YP_540895.1 CDS ydiP NC_007946.1 1813978 1814889 R transcriptional regulator YdiP complement(1813978..1814889) Escherichia coli UTI89 3992943 YP_540896.1 CDS UTI89_C1889 NC_007946.1 1814992 1815168 R hypothetical protein complement(1814992..1815168) Escherichia coli UTI89 3992944 YP_540897.2 CDS ydiQ NC_007946.1 1815205 1815969 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1815205..1815969 Escherichia coli UTI89 3992945 YP_540898.1 CDS ydiR NC_007946.1 1815989 1816927 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1815989..1816927 Escherichia coli UTI89 3992946 YP_540899.1 CDS ydiS NC_007946.1 1816982 1818271 D hypothetical protein 1816982..1818271 Escherichia coli UTI89 3992947 YP_540900.1 CDS ydiT NC_007946.1 1818268 1818561 D ferredoxin-like protein YdiT 1818268..1818561 Escherichia coli UTI89 3992948 YP_540901.1 CDS ydiD NC_007946.1 1818564 1820264 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1818564..1820264 Escherichia coli UTI89 3992949 YP_540902.1 CDS ppsA NC_007946.1 1820321 1822699 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1820321..1822699) Escherichia coli UTI89 3990347 YP_540903.1 CDS ydiA NC_007946.1 1823032 1823865 D hypothetical protein 1823032..1823865 Escherichia coli UTI89 3990348 YP_540904.1 CDS aroH NC_007946.1 1824022 1825068 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1824022..1825068 Escherichia coli UTI89 3990349 YP_540905.1 CDS ydiE NC_007946.1 1825173 1825391 D hypothetical protein 1825173..1825391 Escherichia coli UTI89 3990350 YP_540906.1 CDS ydiU NC_007946.1 1825395 1826831 R hypothetical protein complement(1825395..1826831) Escherichia coli UTI89 3990351 YP_540907.1 CDS ydiV NC_007946.1 1826894 1827607 R hypothetical protein complement(1826894..1827607) Escherichia coli UTI89 3990352 YP_540908.1 CDS nlpC NC_007946.1 1827854 1828318 R lipoprotein NlpC complement(1827854..1828318) Escherichia coli UTI89 3990353 YP_540909.1 CDS btuD NC_007946.1 1828396 1829145 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1828396..1829145) Escherichia coli UTI89 3990354 YP_540910.1 CDS btuE NC_007946.1 1829145 1829696 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(1829145..1829696) Escherichia coli UTI89 3990355 YP_540911.1 CDS btuC NC_007946.1 1829758 1830738 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1829758..1830738) Escherichia coli UTI89 3990356 YP_540912.1 CDS ihfA NC_007946.1 1830839 1831138 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1830839..1831138) Escherichia coli UTI89 3990357 YP_540913.1 CDS pheT NC_007946.1 1831143 1833530 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1831143..1833530) Escherichia coli UTI89 3990358 YP_540914.2 CDS pheS NC_007946.1 1833545 1834528 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1833545..1834528) Escherichia coli UTI89 3990359 YP_540915.1 CDS UTI89_C1908 NC_007946.1 1834608 1834916 D hypothetical protein 1834608..1834916 Escherichia coli UTI89 3990360 YP_540916.1 CDS rplT NC_007946.1 1834979 1835335 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1834979..1835335) Escherichia coli UTI89 3990361 YP_540917.1 CDS rpmI NC_007946.1 1835388 1835585 R 50S ribosomal protein L35 complement(1835388..1835585) Escherichia coli UTI89 3990362 YP_540918.1 CDS infC NC_007946.1 1835682 1836116 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1835682..1836116) Escherichia coli UTI89 3990363 YP_540919.1 CDS thrS NC_007946.1 1836228 1838156 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1836228..1838156) Escherichia coli UTI89 3990364 YP_540920.1 CDS UTI89_C1913 NC_007946.1 1838679 1839113 D hypothetical protein 1838679..1839113 Escherichia coli UTI89 3990365 YP_540921.1 CDS UTI89_C1914 NC_007946.1 1839225 1839602 D hypothetical protein 1839225..1839602 Escherichia coli UTI89 3990366 YP_540922.1 CDS ydiY NC_007946.1 1840040 1840798 R hypothetical protein complement(1840040..1840798) Escherichia coli UTI89 3990367 YP_540923.1 CDS pfkB NC_007946.1 1841081 1842013 D 6-phosphofructokinase 1841081..1842013 Escherichia coli UTI89 3990368 YP_540924.1 CDS UTI89_C1917 NC_007946.1 1842042 1842419 R hypothetical protein complement(1842042..1842419) Escherichia coli UTI89 3990369 YP_540925.1 CDS ydiZ NC_007946.1 1842114 1842404 D hypothetical protein 1842114..1842404 Escherichia coli UTI89 3990370 YP_540926.1 CDS yniA NC_007946.1 1842510 1843370 D hypothetical protein 1842510..1843370 Escherichia coli UTI89 3990371 YP_540927.1 CDS yniB NC_007946.1 1843411 1843947 R hypothetical protein complement(1843411..1843947) Escherichia coli UTI89 3990372 YP_540928.1 CDS yniC NC_007946.1 1844094 1844762 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1844094..1844762 Escherichia coli UTI89 3990373 YP_540929.2 CDS UTI89_C1922 NC_007946.1 1844926 1845516 D hypothetical protein 1844926..1845516 Escherichia coli UTI89 3990374 YP_540930.1 CDS ydjN NC_007946.1 1845649 1847040 D symporter protein YdjN 1845649..1847040 Escherichia coli UTI89 3990375 YP_540931.1 CDS cedA NC_007946.1 1847087 1847350 R cell division modulator complement(1847087..1847350) Escherichia coli UTI89 3990376 YP_540932.1 CDS katE NC_007946.1 1847533 1849794 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1847533..1849794 Escherichia coli UTI89 3990377 YP_540933.1 CDS ydjC NC_007946.1 1849840 1850598 R hypothetical protein complement(1849840..1850598) Escherichia coli UTI89 3990378 YP_540934.1 CDS celF NC_007946.1 1850611 1852032 R 6-phospho-beta-glucosidase complement(1850611..1852032) Escherichia coli UTI89 3990379 YP_540935.1 CDS celD NC_007946.1 1852067 1852909 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1852067..1852909) Escherichia coli UTI89 3990380 YP_540936.1 CDS celC NC_007946.1 1852917 1853267 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1852917..1853267) Escherichia coli UTI89 3990381 YP_540937.1 CDS celB NC_007946.1 1853318 1854676 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1853318..1854676) Escherichia coli UTI89 3990382 YP_540938.1 CDS celA NC_007946.1 1854761 1855081 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1854761..1855081) Escherichia coli UTI89 3990383 YP_540939.1 CDS UTI89_C1932 NC_007946.1 1855102 1855362 R hypothetical protein complement(1855102..1855362) Escherichia coli UTI89 3990384 YP_540940.1 CDS osmE NC_007946.1 1855380 1855718 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1855380..1855718) Escherichia coli UTI89 3990385 YP_540941.1 CDS nadE NC_007946.1 1855920 1856747 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1855920..1856747 Escherichia coli UTI89 3991590 YP_540942.1 CDS ydjQ NC_007946.1 1856977 1857864 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1856977..1857864 Escherichia coli UTI89 3991591 YP_540943.1 CDS ydjR NC_007946.1 1857824 1858462 R hypothetical protein complement(1857824..1858462) Escherichia coli UTI89 3991592 YP_540944.1 CDS UTI89_C1937 NC_007946.1 1858590 1859078 D hypothetical protein 1858590..1859078 Escherichia coli UTI89 3991593 YP_540945.1 CDS spy NC_007946.1 1858602 1859087 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein complement(1858602..1859087) Escherichia coli UTI89 3991594 YP_540946.1 CDS ydjS NC_007946.1 1859417 1860385 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1859417..1860385) Escherichia coli UTI89 3991595 YP_540947.1 CDS astB NC_007946.1 1860378 1861721 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1860378..1861721) Escherichia coli UTI89 3991596 YP_540948.1 CDS astD NC_007946.1 1861718 1863196 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1861718..1863196) Escherichia coli UTI89 3991597 YP_540949.1 CDS astA NC_007946.1 1863193 1864227 R arginine succinyltransferase complement(1863193..1864227) Escherichia coli UTI89 3991598 YP_540950.1 CDS astC NC_007946.1 1864224 1865444 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1864224..1865444) Escherichia coli UTI89 3991599 YP_540951.1 CDS UTI89_C1944 NC_007946.1 1865707 1865877 D hypothetical protein 1865707..1865877 Escherichia coli UTI89 3991600 YP_540952.2 CDS xthA NC_007946.1 1865890 1866696 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1865890..1866696 Escherichia coli UTI89 3991601 YP_540953.1 CDS ydjX NC_007946.1 1866815 1867573 D hypothetical protein 1866815..1867573 Escherichia coli UTI89 3991602 YP_540954.1 CDS ydjY NC_007946.1 1867416 1868255 D hypothetical protein 1867416..1868255 Escherichia coli UTI89 3991603 YP_540955.1 CDS ydjZ NC_007946.1 1868269 1868976 D hypothetical protein 1868269..1868976 Escherichia coli UTI89 3991604 YP_540956.1 CDS ynjA NC_007946.1 1868976 1869524 D hypothetical protein 1868976..1869524 Escherichia coli UTI89 3991605 YP_540957.1 CDS ynjB NC_007946.1 1869534 1870700 D ABC transporter solute-binding protein 1869534..1870700 Escherichia coli UTI89 3991606 YP_540958.1 CDS ynjC NC_007946.1 1870649 1872208 D ABC transporter permease 1870649..1872208 Escherichia coli UTI89 3991607 YP_540959.1 CDS ynjD NC_007946.1 1872175 1872861 D ABC transporter ATP-binding protein 1872175..1872861 Escherichia coli UTI89 3991608 YP_540960.1 CDS UTI89_C1953 NC_007946.1 1872913 1874235 D thiosulfate sulfurtransferase 1872913..1874235 Escherichia coli UTI89 3991609 YP_540961.1 CDS ynjF NC_007946.1 1874244 1874870 R hypothetical protein complement(1874244..1874870) Escherichia coli UTI89 3990651 YP_540962.1 CDS ynjG NC_007946.1 1874951 1875358 D pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1874951..1875358 Escherichia coli UTI89 3990652 YP_540963.1 CDS ynjH NC_007946.1 1875324 1875596 R hypothetical protein complement(1875324..1875596) Escherichia coli UTI89 3990653 YP_540964.1 CDS gdhA NC_007946.1 1875832 1877175 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1875832..1877175 Escherichia coli UTI89 3990654 YP_540965.1 CDS topB NC_007946.1 1877252 1879207 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1877252..1879207) Escherichia coli UTI89 3990655 YP_540966.1 CDS selD NC_007946.1 1879212 1880261 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1879212..1880261) Escherichia coli UTI89 3990656 YP_540967.1 CDS ydjA NC_007946.1 1880372 1880941 R hypothetical protein complement(1880372..1880941) Escherichia coli UTI89 3990657 YP_540968.1 CDS UTI89_C1961 NC_007946.1 1880977 1881141 D hypothetical protein 1880977..1881141 Escherichia coli UTI89 3990658 YP_540969.1 CDS sppA NC_007946.1 1881084 1882940 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1881084..1882940 Escherichia coli UTI89 3990659 YP_540970.1 CDS ansA NC_007946.1 1883107 1884123 D converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 1883107..1884123 Escherichia coli UTI89 3990660 YP_540971.2 CDS ydjB NC_007946.1 1884134 1884775 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1884134..1884775 Escherichia coli UTI89 3990661 YP_540972.1 CDS ydjE NC_007946.1 1884868 1886295 R metabolite transport protein YdjE complement(1884868..1886295) Escherichia coli UTI89 3990662 YP_540973.1 CDS ydjF NC_007946.1 1886344 1887102 R DEOR-type transcriptional regulator complement(1886344..1887102) Escherichia coli UTI89 3990663 YP_540974.1 CDS ydjG NC_007946.1 1887239 1888219 R oxidoreductase YdjG complement(1887239..1888219) Escherichia coli UTI89 3990664 YP_540975.1 CDS ydjH NC_007946.1 1888229 1889197 R sugar kinase YdjH complement(1888229..1889197) Escherichia coli UTI89 3990665 YP_540976.1 CDS ydjI NC_007946.1 1889181 1890017 R membrane protein YdjI complement(1889181..1890017) Escherichia coli UTI89 3990666 YP_540977.1 CDS ydjJ NC_007946.1 1890038 1891081 R zinc-type alcohol dehydrogenase-like protein YdjJ complement(1890038..1891081) Escherichia coli UTI89 3990667 YP_540978.1 CDS ydjK NC_007946.1 1891098 1892477 R metabolite transport protein YdjK complement(1891098..1892477) Escherichia coli UTI89 3990668 YP_540979.1 CDS ydjL NC_007946.1 1892504 1893580 R oxidoreductase complement(1892504..1893580) Escherichia coli UTI89 3990669 YP_540980.1 CDS yeaC NC_007946.1 1893950 1894267 R hypothetical protein complement(1893950..1894267) Escherichia coli UTI89 3990670 YP_540981.1 CDS msrB NC_007946.1 1894264 1894707 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1894264..1894707) Escherichia coli UTI89 3990671 YP_540982.1 CDS gapA NC_007946.1 1895010 1896014 D glyceraldehyde-3-phosphate dehydrogenase A 1895010..1896014 Escherichia coli UTI89 3990672 YP_540983.1 CDS yeaD NC_007946.1 1896077 1896982 D hypothetical protein 1896077..1896982 Escherichia coli UTI89 3990673 YP_540984.1 CDS yeaE NC_007946.1 1897033 1897932 R hypothetical protein complement(1897033..1897932) Escherichia coli UTI89 3990674 YP_540985.1 CDS yeaF NC_007946.1 1897977 1898723 R hypothetical protein complement(1897977..1898723) Escherichia coli UTI89 3990675 YP_540986.1 CDS yeaG NC_007946.1 1899159 1901093 D hypothetical protein 1899159..1901093 Escherichia coli UTI89 3990676 YP_540987.1 CDS yeaH NC_007946.1 1901206 1902489 D hypothetical protein 1901206..1902489 Escherichia coli UTI89 3990677 YP_540988.1 CDS yeaI NC_007946.1 1902636 1904111 D hypothetical protein 1902636..1904111 Escherichia coli UTI89 3990678 YP_540989.1 CDS yeaJ NC_007946.1 1904112 1905782 D hypothetical protein 1904112..1905782 Escherichia coli UTI89 3990679 YP_540990.1 CDS UTI89_C1983 NC_007946.1 1905825 1906328 D hypothetical protein 1905825..1906328 Escherichia coli UTI89 3990680 YP_540991.1 CDS UTI89_C1984 NC_007946.1 1906329 1906481 R hypothetical protein complement(1906329..1906481) Escherichia coli UTI89 3990681 YP_540992.1 CDS yeaL NC_007946.1 1906603 1907049 D hypothetical protein 1906603..1907049 Escherichia coli UTI89 3990682 YP_540993.1 CDS yeaM NC_007946.1 1907006 1907827 R transcriptional regulator YeaM complement(1907006..1907827) Escherichia coli UTI89 3990683 YP_540994.1 CDS UTI89_C1987 NC_007946.1 1907924 1909105 D amino acid/amine transport protein 1907924..1909105 Escherichia coli UTI89 3990684 YP_540995.1 CDS yeaO NC_007946.1 1909160 1909507 D hypothetical protein 1909160..1909507 Escherichia coli UTI89 3990685 YP_540997.1 CDS yoaF NC_007946.1 1909529 1909783 R hypothetical protein complement(1909529..1909783) Escherichia coli UTI89 3990687 YP_540998.1 CDS yeaP NC_007946.1 1909837 1910991 D hypothetical protein 1909837..1910991 Escherichia coli UTI89 3990688 YP_540999.1 CDS yeaQ NC_007946.1 1911258 1911506 R hypothetical protein complement(1911258..1911506) Escherichia coli UTI89 3990689 YP_541000.1 CDS UTI89_C1993 NC_007946.1 1911518 1911640 R hypothetical protein complement(1911518..1911640) Escherichia coli UTI89 3990730 YP_541001.1 CDS yoaG NC_007946.1 1911654 1911836 R hypothetical protein complement(1911654..1911836) Escherichia coli UTI89 3990731 YP_541002.1 CDS yeaR NC_007946.1 1911840 1912199 R hypothetical protein complement(1911840..1912199) Escherichia coli UTI89 3990732 YP_541003.1 CDS yeaS NC_007946.1 1912372 1913010 R leucine export protein LeuE complement(1912372..1913010) Escherichia coli UTI89 3990733 YP_541004.1 CDS UTI89_C1997 NC_007946.1 1913293 1913463 D hypothetical protein 1913293..1913463 Escherichia coli UTI89 3990734 YP_541005.1 CDS rnd NC_007946.1 1913553 1914680 R ribonuclease D complement(1913553..1914680) Escherichia coli UTI89 3990735 YP_541006.1 CDS fadD NC_007946.1 1914750 1916501 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1914750..1916501) Escherichia coli UTI89 3990736 YP_541007.1 CDS yeaY NC_007946.1 1916640 1917221 R hypothetical protein complement(1916640..1917221) Escherichia coli UTI89 3990737 YP_541008.1 CDS yeaZ NC_007946.1 1917261 1917956 R O-sialoglycoprotein endopeptidase complement(1917261..1917956) Escherichia coli UTI89 3990738 YP_541009.1 CDS UTI89_C2002 NC_007946.1 1918014 1919924 R hypothetical protein complement(1918014..1919924) Escherichia coli UTI89 3990739 YP_541010.1 CDS UTI89_C2003 NC_007946.1 1919957 1920319 R hypothetical protein complement(1919957..1920319) Escherichia coli UTI89 3990740 YP_541011.1 CDS UTI89_C2004 NC_007946.1 1920008 1920400 D hypothetical protein 1920008..1920400 Escherichia coli UTI89 3990741 YP_541012.1 CDS yoaC NC_007946.1 1920762 1921121 D hypothetical protein 1920762..1921121 Escherichia coli UTI89 3990742 YP_541013.1 CDS UTI89_C2006 NC_007946.1 1921238 1921402 D hypothetical protein 1921238..1921402 Escherichia coli UTI89 3990743 YP_541014.1 CDS yoaH NC_007946.1 1921241 1921420 R hypothetical protein complement(1921241..1921420) Escherichia coli UTI89 3990744 YP_541015.1 CDS pabB NC_007946.1 1921494 1922855 D para-aminobenzoate synthase component I 1921494..1922855 Escherichia coli UTI89 3990745 YP_541016.1 CDS yeaB NC_007946.1 1922859 1923437 D hypothetical protein 1922859..1923437 Escherichia coli UTI89 3990746 YP_541017.1 CDS sdaA NC_007946.1 1923621 1924985 D L-serine dehydratase 1 1923621..1924985 Escherichia coli UTI89 3990747 YP_541018.1 CDS UTI89_C2011 NC_007946.1 1925086 1926714 D hypothetical protein 1925086..1926714 Escherichia coli UTI89 3990748 YP_541019.1 CDS yoaE NC_007946.1 1926718 1928274 R transmembrane protein complement(1926718..1928274) Escherichia coli UTI89 3989881 YP_541020.1 CDS UTI89_C2013 NC_007946.1 1928262 1928471 R hypothetical protein complement(1928262..1928471) Escherichia coli UTI89 3989882 YP_541021.1 CDS manX NC_007946.1 1928737 1929708 D PTS system mannose-specific transporter subunit IIAB 1928737..1929708 Escherichia coli UTI89 3989883 YP_541022.1 CDS manY NC_007946.1 1929771 1930571 D PTS system mannose-specific transporter subunit IIC 1929771..1930571 Escherichia coli UTI89 3989884 YP_541023.1 CDS UTI89_C2016 NC_007946.1 1929867 1930628 R hypothetical protein complement(1929867..1930628) Escherichia coli UTI89 3989885 YP_541024.1 CDS manZ NC_007946.1 1930575 1931435 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1930575..1931435 Escherichia coli UTI89 3989886 YP_541025.1 CDS yobD NC_007946.1 1931490 1931948 D hypothetical protein 1931490..1931948 Escherichia coli UTI89 3989887 YP_541026.1 CDS UTI89_C2019 NC_007946.1 1932323 1932943 D membrane protein YebN; hypothetical protein 1932323..1932943 Escherichia coli UTI89 3989888 YP_541027.1 CDS rrmA NC_007946.1 1932940 1933749 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase complement(1932940..1933749) Escherichia coli UTI89 3989889 YP_541028.1 CDS cspC NC_007946.1 1933915 1934124 R cold shock-like protein CspC complement(1933915..1934124) Escherichia coli UTI89 3989890 YP_541029.1 CDS yobF NC_007946.1 1934137 1934280 R hypothetical protein complement(1934137..1934280) Escherichia coli UTI89 3989891 YP_541030.1 CDS UTI89_C2023 NC_007946.1 1934242 1934505 D hypothetical protein 1934242..1934505 Escherichia coli UTI89 3989892 YP_541032.1 CDS yebO NC_007946.1 1934951 1935238 R hypothetical protein complement(1934951..1935238) Escherichia coli UTI89 3989894 YP_541033.1 CDS mgrB NC_007946.1 1935313 1935456 R synonym: yobG , b1826; hypothetical protein complement(1935313..1935456) Escherichia coli UTI89 3989895 YP_541034.1 CDS UTI89_C2027 NC_007946.1 1935615 1935854 D hypothetical protein 1935615..1935854 Escherichia coli UTI89 3989896 YP_541035.1 CDS kdgR NC_007946.1 1935998 1936789 R transcriptional regulator KdgR complement(1935998..1936789) Escherichia coli UTI89 3989897 YP_541036.1 CDS yebQ NC_007946.1 1936855 1938339 D transport protein YebQ 1936855..1938339 Escherichia coli UTI89 3989898 YP_541037.1 CDS htpX NC_007946.1 1938385 1939266 R metalloprotease; heat shock protein HtpX complement(1938385..1939266) Escherichia coli UTI89 3989899 YP_541038.1 CDS prc NC_007946.1 1939458 1941506 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1939458..1941506) Escherichia coli UTI89 3989900 YP_541039.1 CDS proQ NC_007946.1 1941526 1942224 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(1941526..1942224) Escherichia coli UTI89 3989842 YP_541040.1 CDS UTI89_C2033 NC_007946.1 1942321 1942872 R hypothetical protein complement(1942321..1942872) Escherichia coli UTI89 3989843 YP_541041.1 CDS yebS NC_007946.1 1942948 1944231 D hypothetical protein 1942948..1944231 Escherichia coli UTI89 3989844 YP_541042.1 CDS yebT NC_007946.1 1944158 1946833 D hypothetical protein 1944158..1946833 Escherichia coli UTI89 3989845 YP_541043.1 CDS yebU NC_007946.1 1946907 1948352 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1946907..1948352 Escherichia coli UTI89 3989846 YP_541044.1 CDS yebV NC_007946.1 1948455 1948706 D hypothetical protein 1948455..1948706 Escherichia coli UTI89 3989847 YP_541045.1 CDS yebW NC_007946.1 1948727 1949002 D hypothetical protein 1948727..1949002 Escherichia coli UTI89 3989848 YP_541046.1 CDS pphA NC_007946.1 1949003 1949662 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(1949003..1949662) Escherichia coli UTI89 3989849 YP_541047.1 CDS UTI89_C2040 NC_007946.1 1949884 1950036 R hypothetical protein complement(1949884..1950036) Escherichia coli UTI89 3989850 YP_541048.1 CDS yebY NC_007946.1 1950054 1950395 R hypothetical protein complement(1950054..1950395) Escherichia coli UTI89 3989851 YP_541049.1 CDS yebZ NC_007946.1 1950408 1951280 R hypothetical protein complement(1950408..1951280) Escherichia coli UTI89 3989852 YP_541050.1 CDS yobA NC_007946.1 1951284 1951658 R hypothetical protein complement(1951284..1951658) Escherichia coli UTI89 3989853 YP_541051.2 CDS holE NC_007946.1 1951797 1952027 D DNA polymerase III subunit theta 1951797..1952027 Escherichia coli UTI89 3989854 YP_541052.1 CDS UTI89_C2045 NC_007946.1 1952129 1952785 D hypothetical protein 1952129..1952785 Escherichia coli UTI89 3989855 YP_541053.1 CDS exoX NC_007946.1 1952808 1953470 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1952808..1953470 Escherichia coli UTI89 3989856 YP_541054.1 CDS ptrB NC_007946.1 1953467 1955527 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(1953467..1955527) Escherichia coli UTI89 3989857 YP_541055.1 CDS UTI89_C2048 NC_007946.1 1955613 1956215 D hypothetical protein 1955613..1956215 Escherichia coli UTI89 3989858 YP_541056.1 CDS yebE NC_007946.1 1955736 1956395 R hypothetical protein complement(1955736..1956395) Escherichia coli UTI89 3989859 YP_541057.1 CDS yebF NC_007946.1 1956722 1957090 R secreted protein; unknown function; hypothetical protein complement(1956722..1957090) Escherichia coli UTI89 3989860 YP_541058.1 CDS yebG NC_007946.1 1957145 1957435 R DNA damage-inducible protein YebG complement(1957145..1957435) Escherichia coli UTI89 3989978 YP_541059.1 CDS purT NC_007946.1 1957569 1958747 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1957569..1958747 Escherichia coli UTI89 3989979 YP_541060.1 CDS eda NC_007946.1 1958803 1959444 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1958803..1959444) Escherichia coli UTI89 3989980 YP_541061.1 CDS edd NC_007946.1 1959481 1961358 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1959481..1961358) Escherichia coli UTI89 3989981 YP_541062.1 CDS zwf NC_007946.1 1961527 1963002 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1961527..1963002) Escherichia coli UTI89 3989982 YP_541063.1 CDS UTI89_C2056 NC_007946.1 1963168 1963317 R hypothetical protein complement(1963168..1963317) Escherichia coli UTI89 3989983 YP_541064.1 CDS yebK NC_007946.1 1963340 1964209 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1963340..1964209 Escherichia coli UTI89 3989984 YP_541065.1 CDS pykA NC_007946.1 1964196 1965779 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1964196..1965779 Escherichia coli UTI89 3989985 YP_541066.1 CDS msbB NC_007946.1 1965911 1966882 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(1965911..1966882) Escherichia coli UTI89 3989986 YP_541067.1 CDS yebA NC_007946.1 1967001 1968323 R hypothetical protein complement(1967001..1968323) Escherichia coli UTI89 3989987 YP_541068.1 CDS znuA NC_007946.1 1968339 1969397 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component complement(1968339..1969397) Escherichia coli UTI89 3989988 YP_541069.1 CDS znuC NC_007946.1 1969350 1970105 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1969350..1970105 Escherichia coli UTI89 3989989 YP_541070.1 CDS znuB NC_007946.1 1970102 1970887 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 1970102..1970887 Escherichia coli UTI89 3989990 YP_541071.1 CDS ruvB NC_007946.1 1971104 1972114 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1971104..1972114) Escherichia coli UTI89 3989991 YP_541072.1 CDS ruvA NC_007946.1 1972123 1972734 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1972123..1972734) Escherichia coli UTI89 3989992 YP_541073.2 CDS yebB NC_007946.1 1973010 1973612 D hypothetical protein 1973010..1973612 Escherichia coli UTI89 3989993 YP_541074.1 CDS ruvC NC_007946.1 1973614 1974135 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1973614..1974135) Escherichia coli UTI89 3989994 YP_541075.1 CDS yebC NC_007946.1 1974170 1974910 R hypothetical protein complement(1974170..1974910) Escherichia coli UTI89 3989995 YP_541076.1 CDS ntpA NC_007946.1 1974939 1975382 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(1974939..1975382) Escherichia coli UTI89 3989996 YP_541077.1 CDS aspS NC_007946.1 1975384 1977156 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1975384..1977156) Escherichia coli UTI89 3989997 YP_541078.2 CDS yecD NC_007946.1 1977466 1978032 D hypothetical protein 1977466..1978032 Escherichia coli UTI89 3989664 YP_541079.1 CDS yecE NC_007946.1 1978029 1978847 D hypothetical protein 1978029..1978847 Escherichia coli UTI89 3989665 YP_541080.1 CDS yecN NC_007946.1 1978870 1979295 D hypothetical protein 1978870..1979295 Escherichia coli UTI89 3989666 YP_541081.1 CDS yecO NC_007946.1 1979336 1980079 D hypothetical protein 1979336..1980079 Escherichia coli UTI89 3989667 YP_541082.1 CDS yecP NC_007946.1 1980076 1981047 D hypothetical protein 1980076..1981047 Escherichia coli UTI89 3989668 YP_541083.1 CDS bisZ NC_007946.1 1981212 1983659 R trimethylamine-N-oxide reductase 2 complement(1981212..1983659) Escherichia coli UTI89 3989669 YP_541084.1 CDS yecK NC_007946.1 1983666 1984766 R cytochrome c-type protein TorY complement(1983666..1984766) Escherichia coli UTI89 3989670 YP_541085.1 CDS UTI89_C2078 NC_007946.1 1985154 1985900 R copper homeostasis protein CutC complement(1985154..1985900) Escherichia coli UTI89 3989671 YP_541086.1 CDS yecM NC_007946.1 1985914 1986486 R hypothetical protein complement(1985914..1986486) Escherichia coli UTI89 3989672 YP_541087.1 CDS argS NC_007946.1 1986696 1988429 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1986696..1988429 Escherichia coli UTI89 3989673 YP_541088.1 CDS flhE NC_007946.1 1988482 1988874 R flagellar protein FlhE complement(1988482..1988874) Escherichia coli UTI89 3989674 YP_541089.2 CDS flhA NC_007946.1 1988874 1990952 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(1988874..1990952) Escherichia coli UTI89 3989675 YP_541090.1 CDS flhB NC_007946.1 1990945 1992093 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(1990945..1992093) Escherichia coli UTI89 3989676 YP_541091.1 CDS UTI89_C2084 NC_007946.1 1992126 1992272 D hypothetical protein 1992126..1992272 Escherichia coli UTI89 3989677 YP_541092.2 CDS cheZ NC_007946.1 1992302 1992946 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(1992302..1992946) Escherichia coli UTI89 3989678 YP_541093.1 CDS cheY NC_007946.1 1992957 1993346 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(1992957..1993346) Escherichia coli UTI89 3989679 YP_541094.1 CDS cheB NC_007946.1 1993361 1994410 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(1993361..1994410) Escherichia coli UTI89 3989680 YP_541095.1 CDS cheR NC_007946.1 1994413 1995273 R methylates the MCP; chemotaxis methyltransferase CheR complement(1994413..1995273) Escherichia coli UTI89 3989681 YP_541096.1 CDS tar NC_007946.1 1995564 1997246 R methyl-accepting chemotaxis protein II complement(1995564..1997246) Escherichia coli UTI89 3989682 YP_541097.1 CDS cheW NC_007946.1 1997370 1997873 R purine-binding chemotaxis protein complement(1997370..1997873) Escherichia coli UTI89 3991532 YP_541098.1 CDS cheA NC_007946.1 1997894 1999912 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(1997894..1999912) Escherichia coli UTI89 3991533 YP_541099.1 CDS motB NC_007946.1 1999863 2000789 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(1999863..2000789) Escherichia coli UTI89 3991534 YP_541100.1 CDS motA NC_007946.1 2000786 2001673 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2000786..2001673) Escherichia coli UTI89 3991535 YP_541101.1 CDS flhC NC_007946.1 2001800 2002378 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2001800..2002378) Escherichia coli UTI89 3991536 YP_541102.1 CDS flhD NC_007946.1 2002381 2002740 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2002381..2002740) Escherichia coli UTI89 3991537 YP_541103.1 CDS yecG NC_007946.1 2003511 2003939 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2003511..2003939 Escherichia coli UTI89 3991538 YP_541104.1 CDS otsA NC_007946.1 2003946 2005379 R trehalose-6-phosphate synthase complement(2003946..2005379) Escherichia coli UTI89 3991539 YP_541105.1 CDS otsB NC_007946.1 2005345 2006202 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2005345..2006202) Escherichia coli UTI89 3991540 YP_541106.1 CDS araH NC_007946.1 2006312 2007301 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(2006312..2007301) Escherichia coli UTI89 3991541 YP_541107.2 CDS araG NC_007946.1 2007313 2008827 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2007313..2008827) Escherichia coli UTI89 3991542 YP_541108.1 CDS araF NC_007946.1 2008897 2009937 R L-arabinose-binding periplasmic protein complement(2008897..2009937) Escherichia coli UTI89 3991543 YP_541109.1 CDS yecI NC_007946.1 2010683 2011186 D ferritin 2010683..2011186 Escherichia coli UTI89 3991544 YP_541110.1 CDS yecJ NC_007946.1 2011264 2011515 R hypothetical protein complement(2011264..2011515) Escherichia coli UTI89 3991545 YP_541112.1 CDS yecR NC_007946.1 2011980 2012303 D hypothetical protein 2011980..2012303 Escherichia coli UTI89 3991547 YP_541113.1 CDS ftnA NC_007946.1 2012460 2012972 D cytoplasmic iron storage protein; ferritin 2012460..2012972 Escherichia coli UTI89 3991548 YP_541114.1 CDS yecH NC_007946.1 2013010 2013249 R hypothetical protein complement(2013010..2013249) Escherichia coli UTI89 3991549 YP_541115.1 CDS tyrP NC_007946.1 2013440 2014651 D tyrosine-specific transport protein 2013440..2014651 Escherichia coli UTI89 3991550 YP_541116.1 CDS yecA NC_007946.1 2014702 2015367 R hypothetical protein complement(2014702..2015367) Escherichia coli UTI89 3991551 YP_541117.1 CDS pgsA NC_007946.1 2016016 2016564 R phosphatidylglycerophosphate synthetase complement(2016016..2016564) Escherichia coli UTI89 3993201 YP_541118.1 CDS uvrC NC_007946.1 2016621 2018453 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2016621..2018453) Escherichia coli UTI89 3993202 YP_541119.1 CDS uvrY NC_007946.1 2018450 2019106 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2018450..2019106) Escherichia coli UTI89 3993203 YP_541120.1 CDS yecF NC_007946.1 2019565 2019789 D hypothetical protein 2019565..2019789 Escherichia coli UTI89 3993204 YP_541121.2 CDS sdiA NC_007946.1 2019857 2020579 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2019857..2020579) Escherichia coli UTI89 3993205 YP_541122.1 CDS yecC NC_007946.1 2020809 2021561 R amino-acid ABC transporter ATP-binding protein YecC complement(2020809..2021561) Escherichia coli UTI89 3993206 YP_541123.1 CDS yecS NC_007946.1 2021558 2022226 R transport system permease complement(2021558..2022226) Escherichia coli UTI89 3993207 YP_541124.1 CDS UTI89_C2120 NC_007946.1 2022241 2023227 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2022241..2023227) Escherichia coli UTI89 3993208 YP_541125.1 CDS fliY NC_007946.1 2023332 2024189 R cystine transporter subunit complement(2023332..2024189) Escherichia coli UTI89 3993209 YP_541126.1 CDS fliZ NC_007946.1 2024220 2024807 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2024220..2024807) Escherichia coli UTI89 3993210 YP_541127.1 CDS fliA NC_007946.1 2024817 2025536 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2024817..2025536) Escherichia coli UTI89 3993211 YP_541128.1 CDS fliC NC_007946.1 2025856 2027613 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2025856..2027613) Escherichia coli UTI89 3993212 YP_541129.1 CDS fliD NC_007946.1 2027879 2029285 D involved in flagellin assembly; flagellar capping protein 2027879..2029285 Escherichia coli UTI89 3993213 YP_541130.1 CDS fliS NC_007946.1 2029310 2029720 D flagellin specific chaperone; flagellar protein FliS 2029310..2029720 Escherichia coli UTI89 3994762 YP_541131.1 CDS fliT NC_007946.1 2029720 2030085 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2029720..2030085 Escherichia coli UTI89 3994763 YP_541132.1 CDS amyA NC_007946.1 2030163 2031650 D converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2030163..2031650 Escherichia coli UTI89 3994764 YP_541133.1 CDS yedD NC_007946.1 2031684 2032100 R hypothetical protein complement(2031684..2032100) Escherichia coli UTI89 3994765 YP_541134.1 CDS yedE NC_007946.1 2032284 2033489 D hypothetical protein 2032284..2033489 Escherichia coli UTI89 3994766 YP_541135.1 CDS yedF NC_007946.1 2033486 2033719 D hypothetical protein 2033486..2033719 Escherichia coli UTI89 3994767 YP_541136.1 CDS yedK NC_007946.1 2033828 2034496 D hypothetical protein 2033828..2034496 Escherichia coli UTI89 3994768 YP_541137.1 CDS UTI89_C2133 NC_007946.1 2035063 2036091 D porin 2035063..2036091 Escherichia coli UTI89 3994769 YP_541138.1 CDS ybcM NC_007946.1 2036593 2037390 R transcriptional regulator YbcM complement(2036593..2037390) Escherichia coli UTI89 3994770 YP_541139.1 CDS ybcL NC_007946.1 2037400 2037951 R DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor complement(2037400..2037951) Escherichia coli UTI89 3994771 YP_541140.1 CDS emrE NC_007946.1 2038120 2038632 R member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein complement(2038120..2038632) Escherichia coli UTI89 3994772 YP_541141.2 CDS fliE NC_007946.1 2038797 2039111 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2038797..2039111) Escherichia coli UTI89 3994773 YP_541142.1 CDS fliF NC_007946.1 2039326 2040984 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2039326..2040984 Escherichia coli UTI89 3994774 YP_541143.1 CDS fliG NC_007946.1 2040977 2041972 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2040977..2041972 Escherichia coli UTI89 3994775 YP_541144.1 CDS fliH NC_007946.1 2041944 2042651 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2041944..2042651 Escherichia coli UTI89 3994776 YP_541145.1 CDS fliI NC_007946.1 2042651 2044024 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2042651..2044024 Escherichia coli UTI89 3994777 YP_541146.1 CDS fliJ NC_007946.1 2044043 2044486 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2044043..2044486 Escherichia coli UTI89 3994778 YP_541147.1 CDS fliK NC_007946.1 2044483 2045610 D flagellar hook-length control protein 2044483..2045610 Escherichia coli UTI89 3994779 YP_541148.1 CDS fliL NC_007946.1 2045715 2046179 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2045715..2046179 Escherichia coli UTI89 3994780 YP_541149.1 CDS fliM NC_007946.1 2046139 2047188 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2046139..2047188 Escherichia coli UTI89 3994781 YP_541150.1 CDS fliN NC_007946.1 2047185 2047598 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2047185..2047598 Escherichia coli UTI89 3994538 YP_541151.1 CDS fliO NC_007946.1 2047598 2047966 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2047598..2047966 Escherichia coli UTI89 3994539 YP_541152.1 CDS fliP NC_007946.1 2047966 2048703 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2047966..2048703 Escherichia coli UTI89 3994540 YP_541153.1 CDS fliQ NC_007946.1 2048713 2048982 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2048713..2048982 Escherichia coli UTI89 3994541 YP_541154.1 CDS fliR NC_007946.1 2048991 2049776 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2048991..2049776 Escherichia coli UTI89 3994542 YP_541155.1 CDS rcsA NC_007946.1 2050066 2050689 D capsular polysaccharide synthesis DNA-binding transcriptional regulator 2050066..2050689 Escherichia coli UTI89 3994543 YP_541156.1 CDS dsrB NC_007946.1 2050733 2050921 R transcription is regulated by RpoS and DsrA RNA; hypothetical protein complement(2050733..2050921) Escherichia coli UTI89 3994544 YP_541157.1 CDS UTI89_C2153 NC_007946.1 2050766 2051041 D hypothetical protein 2050766..2051041 Escherichia coli UTI89 3994545 YP_541158.1 CDS UTI89_C2154 NC_007946.1 2051018 2051368 R hypothetical protein complement(2051018..2051368) Escherichia coli UTI89 3994546 YP_541159.1 CDS yodD NC_007946.1 2051069 2051311 D hypothetical protein 2051069..2051311 Escherichia coli UTI89 3994547 YP_541160.1 CDS UTI89_C2156 NC_007946.1 2051609 2052424 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2051609..2052424 Escherichia coli UTI89 3994548 YP_541161.1 CDS UTI89_C2157 NC_007946.1 2052421 2054130 R hypothetical protein complement(2052421..2054130) Escherichia coli UTI89 3994549 YP_541162.1 CDS UTI89_C2158 NC_007946.1 2054036 2054224 R hypothetical protein complement(2054036..2054224) Escherichia coli UTI89 3994550 YP_541163.1 CDS UTI89_C2159 NC_007946.1 2054547 2055464 R hypothetical protein complement(2054547..2055464) Escherichia coli UTI89 3994551 YP_541164.1 CDS yedA NC_007946.1 2055637 2056557 D hypothetical protein 2055637..2056557 Escherichia coli UTI89 3994552 YP_541165.1 CDS vsr NC_007946.1 2056546 2057016 R DNA mismatch endonuclease, patch repair protein complement(2056546..2057016) Escherichia coli UTI89 3994553 YP_541166.1 CDS dcm NC_007946.1 2056997 2058415 R DNA cytosine methylase complement(2056997..2058415) Escherichia coli UTI89 3994554 YP_541167.1 CDS yedJ NC_007946.1 2058482 2059204 R hypothetical protein complement(2058482..2059204) Escherichia coli UTI89 3994555 YP_541168.1 CDS UTI89_C2164 NC_007946.1 2059217 2059600 R hypothetical protein complement(2059217..2059600) Escherichia coli UTI89 3994556 YP_541169.1 CDS UTI89_C2165 NC_007946.1 2060118 2061263 D outer membrane protein N 2060118..2061263 Escherichia coli UTI89 3992544 YP_541170.1 CDS hchA NC_007946.1 2061860 2062711 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2061860..2062711 Escherichia coli UTI89 3992545 YP_541171.1 CDS yedV NC_007946.1 2062818 2064176 R 2-component sensor protein complement(2062818..2064176) Escherichia coli UTI89 3992546 YP_541172.2 CDS yedW NC_007946.1 2064176 2064847 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2064176..2064847) Escherichia coli UTI89 3992547 YP_541173.1 CDS UTI89_C2169 NC_007946.1 2064980 2065393 D hypothetical protein 2064980..2065393 Escherichia coli UTI89 3992548 YP_541174.1 CDS yedY NC_007946.1 2065502 2066506 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2065502..2066506 Escherichia coli UTI89 3992549 YP_541175.1 CDS yedZ NC_007946.1 2066507 2067142 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2066507..2067142 Escherichia coli UTI89 3992550 YP_541176.1 CDS yodA NC_007946.1 2067399 2068049 D hypothetical protein 2067399..2068049 Escherichia coli UTI89 3992551 YP_541177.1 CDS UTI89_C2173 NC_007946.1 2068085 2068414 D hypothetical protein 2068085..2068414 Escherichia coli UTI89 3992552 YP_541178.1 CDS UTI89_C2175 NC_007946.1 2068863 2069699 D hypothetical protein 2068863..2069699 Escherichia coli UTI89 3992554 YP_541179.1 CDS UTI89_C2177 NC_007946.1 2070256 2071218 D integrase 2070256..2071218 Escherichia coli UTI89 3992556 YP_541180.1 CDS ybtS NC_007946.1 2071493 2072797 R catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 complement(2071493..2072797) Escherichia coli UTI89 3992557 YP_541181.1 CDS ybtX NC_007946.1 2072825 2074228 R hypothetical protein complement(2072825..2074228) Escherichia coli UTI89 3992558 YP_541182.1 CDS UTI89_C2180 NC_007946.1 2074098 2075927 R ABC transporter protein complement(2074098..2075927) Escherichia coli UTI89 3992559 YP_541183.1 CDS ybtP NC_007946.1 2075887 2077689 R ABC transporter inner membrane protein complement(2075887..2077689) Escherichia coli UTI89 3992560 YP_541184.1 CDS UTI89_C2182 NC_007946.1 2077856 2078815 D AraC family transcriptional regulator 2077856..2078815 Escherichia coli UTI89 3992561 YP_541185.1 CDS irp2 NC_007946.1 2078988 2085113 D peptide synthetase-like protein 2078988..2085113 Escherichia coli UTI89 3994059 YP_541186.1 CDS irp1 NC_007946.1 2085201 2094692 D HMWP1 nonribosomal peptide/polyketide synthase 2085201..2094692 Escherichia coli UTI89 3994060 YP_541187.1 CDS ybtU NC_007946.1 2094689 2095789 D thiazolinyl-S-HMWP1 reductase 2094689..2095789 Escherichia coli UTI89 3994061 YP_541188.1 CDS ybtT NC_007946.1 2095801 2096589 D hypothetical protein 2095801..2096589 Escherichia coli UTI89 3994062 YP_541189.1 CDS ybtE NC_007946.1 2096593 2098170 D salicyl-AMP ligase; siderophore biosynthetic protein 2096593..2098170 Escherichia coli UTI89 3994063 YP_541190.1 CDS fyuA NC_007946.1 2098302 2100323 D pesticin receptor 2098302..2100323 Escherichia coli UTI89 3994064 YP_541191.1 CDS UTI89_C2189 NC_007946.1 2100917 2101723 D hypothetical protein 2100917..2101723 Escherichia coli UTI89 3994065 YP_541192.1 CDS UTI89_C2190 NC_007946.1 2101650 2101820 D hypothetical protein 2101650..2101820 Escherichia coli UTI89 3994066 YP_541193.1 CDS UTI89_C2191 NC_007946.1 2101856 2103325 D hypothetical protein 2101856..2103325 Escherichia coli UTI89 3994067 YP_541194.1 CDS UTI89_C2192 NC_007946.1 2103338 2103814 D hypothetical protein 2103338..2103814 Escherichia coli UTI89 3994068 YP_541195.1 CDS UTI89_C2193 NC_007946.1 2103942 2104994 R hypothetical protein complement(2103942..2104994) Escherichia coli UTI89 3994069 YP_541196.1 CDS shiA NC_007946.1 2105309 2106625 D shikimate transporter 2105309..2106625 Escherichia coli UTI89 3994070 YP_541197.2 CDS amn NC_007946.1 2106727 2108181 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2106727..2108181 Escherichia coli UTI89 3994071 YP_541198.1 CDS yeeN NC_007946.1 2108524 2109240 D hypothetical protein 2108524..2109240 Escherichia coli UTI89 3994072 YP_541199.1 CDS UTI89_C2197 NC_007946.1 2109296 2109583 R hypothetical protein complement(2109296..2109583) Escherichia coli UTI89 3994073 YP_541200.1 CDS yeeO NC_007946.1 2109870 2111507 R hypothetical protein complement(2109870..2111507) Escherichia coli UTI89 3994075 YP_541201.1 CDS cbl NC_007946.1 2111628 2112578 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2111628..2112578) Escherichia coli UTI89 3991630 YP_541202.2 CDS nac NC_007946.1 2112680 2113597 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2112680..2113597) Escherichia coli UTI89 3991631 YP_541203.1 CDS UTI89_C2204 NC_007946.1 2114161 2115432 D prophage P4 integrase 2114161..2115432 Escherichia coli UTI89 3991633 YP_541204.1 CDS UTI89_C2205 NC_007946.1 2115434 2115727 R hypothetical protein complement(2115434..2115727) Escherichia coli UTI89 3991634 YP_541205.1 CDS UTI89_C2206 NC_007946.1 2115712 2116224 R hypothetical protein complement(2115712..2116224) Escherichia coli UTI89 3991635 YP_541206.1 CDS UTI89_C2207 NC_007946.1 2116259 2116981 R thioesterase complement(2116259..2116981) Escherichia coli UTI89 3991636 YP_541207.1 CDS UTI89_C2208 NC_007946.1 2116974 2118488 R hypothetical protein complement(2116974..2118488) Escherichia coli UTI89 3991637 YP_541208.1 CDS UTI89_C2209 NC_007946.1 2118501 2120960 R polyketide synthase complement(2118501..2120960) Escherichia coli UTI89 3991638 YP_541209.1 CDS UTI89_C2210 NC_007946.1 2120991 2125445 R peptide synthetase complement(2120991..2125445) Escherichia coli UTI89 3991639 YP_541210.1 CDS UTI89_C2211 NC_007946.1 2125355 2126794 R hypothetical protein complement(2125355..2126794) Escherichia coli UTI89 3991640 YP_541211.1 CDS UTI89_C2212 NC_007946.1 2126856 2128343 R amidase complement(2126856..2128343) Escherichia coli UTI89 3991641 YP_541212.1 CDS UTI89_C2213 NC_007946.1 2128312 2134776 R peptide synthetase complement(2128312..2134776) Escherichia coli UTI89 3991642 YP_541213.1 CDS UTI89_C2214 NC_007946.1 2134787 2141287 R peptide synthetase complement(2134787..2141287) Escherichia coli UTI89 3991643 YP_541214.1 CDS UTI89_C2215 NC_007946.1 2141331 2144363 R polyketide synthase complement(2141331..2144363) Escherichia coli UTI89 3991644 YP_541215.1 CDS UTI89_C2216 NC_007946.1 2144413 2149224 R hypothetical protein complement(2144413..2149224) Escherichia coli UTI89 3991645 YP_541216.1 CDS UTI89_C2217 NC_007946.1 2149257 2150525 R transacylase complement(2149257..2150525) Escherichia coli UTI89 3991646 YP_541217.1 CDS UTI89_C2218 NC_007946.1 2150522 2151550 R acyl-CoA dehydrogenase complement(2150522..2151550) Escherichia coli UTI89 3991647 YP_541218.1 CDS UTI89_C2219 NC_007946.1 2151656 2151904 R hypothetical protein complement(2151656..2151904) Escherichia coli UTI89 3990500 YP_541219.1 CDS UTI89_C2220 NC_007946.1 2151934 2152803 R 3-hydroxyacyl-CoA dehydrogenase complement(2151934..2152803) Escherichia coli UTI89 3990501 YP_541220.1 CDS UTI89_C2221 NC_007946.1 2152813 2155422 R polyketide synthase complement(2152813..2155422) Escherichia coli UTI89 3990502 YP_541221.1 CDS UTI89_C2222 NC_007946.1 2155454 2165083 R peptide/polyketide synthase complement(2155454..2165083) Escherichia coli UTI89 3990503 YP_541222.1 CDS UTI89_C2223 NC_007946.1 2165689 2166423 D hypothetical protein 2165689..2166423 Escherichia coli UTI89 3990504 YP_541223.1 CDS UTI89_C2224 NC_007946.1 2166569 2166835 D transposase 2166569..2166835 Escherichia coli UTI89 3990505 YP_541224.1 CDS UTI89_C2225 NC_007946.1 2166940 2167419 D transposase 2166940..2167419 Escherichia coli UTI89 3990506 YP_541225.1 CDS UTI89_C2226 NC_007946.1 2167410 2167637 D transposase 2167410..2167637 Escherichia coli UTI89 3990507 YP_541226.1 CDS UTI89_C2227 NC_007946.1 2167727 2168152 R hypothetical protein complement(2167727..2168152) Escherichia coli UTI89 3990508 YP_541227.1 CDS erfK NC_007946.1 2168444 2169379 R similar to universal stress protein; hypothetical protein complement(2168444..2169379) Escherichia coli UTI89 3990509 YP_541228.1 CDS cobT NC_007946.1 2169441 2170520 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2169441..2170520) Escherichia coli UTI89 3990510 YP_541229.1 CDS cobS NC_007946.1 2170532 2171311 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2170532..2171311) Escherichia coli UTI89 3990511 YP_541230.1 CDS cobU NC_007946.1 2171272 2171817 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(2171272..2171817) Escherichia coli UTI89 3990512 YP_541231.1 CDS UTI89_C2232 NC_007946.1 2171969 2172091 R hypothetical protein complement(2171969..2172091) Escherichia coli UTI89 3990513 YP_541232.1 CDS UTI89_C2233 NC_007946.1 2172282 2172446 R hypothetical protein complement(2172282..2172446) Escherichia coli UTI89 3990514 YP_541233.1 CDS UTI89_C2234 NC_007946.1 2173489 2175636 D outer membrane receptor for iron compound or colicin 2173489..2175636 Escherichia coli UTI89 3990515 YP_541234.1 CDS UTI89_C2235 NC_007946.1 2175611 2175895 R hypothetical protein complement(2175611..2175895) Escherichia coli UTI89 3990516 YP_541235.1 CDS UTI89_C2236 NC_007946.1 2175624 2175752 D hypothetical protein 2175624..2175752 Escherichia coli UTI89 3990517 YP_541236.1 CDS ibrB NC_007946.1 2176007 2176651 R hypothetical protein complement(2176007..2176651) Escherichia coli UTI89 3990518 YP_541237.1 CDS ibrA NC_007946.1 2176636 2177925 R hypothetical protein complement(2176636..2177925) Escherichia coli UTI89 3994442 YP_541238.1 CDS UTI89_C2239 NC_007946.1 2178850 2179560 D hypothetical protein 2178850..2179560 Escherichia coli UTI89 3994443 YP_541239.1 CDS UTI89_C2240 NC_007946.1 2179574 2180770 D polysaccharide metabolism 2179574..2180770 Escherichia coli UTI89 3994444 YP_541240.1 CDS UTI89_C2241 NC_007946.1 2180805 2181329 D transferase 2180805..2181329 Escherichia coli UTI89 3994445 YP_541241.1 CDS UTI89_C2242 NC_007946.1 2181283 2182104 D hypothetical protein 2181283..2182104 Escherichia coli UTI89 3994446 YP_541242.1 CDS UTI89_C2243 NC_007946.1 2182495 2182815 D hypothetical protein 2182495..2182815 Escherichia coli UTI89 3994447 YP_541243.1 CDS UTI89_C2244 NC_007946.1 2183044 2184177 R hypothetical protein complement(2183044..2184177) Escherichia coli UTI89 3994448 YP_541244.1 CDS UTI89_C2245 NC_007946.1 2185780 2186538 D hypothetical protein 2185780..2186538 Escherichia coli UTI89 3994449 YP_541245.1 CDS UTI89_C2246 NC_007946.1 2187560 2188594 D phosphotriesterase-related protein 2187560..2188594 Escherichia coli UTI89 3994450 YP_541246.1 CDS UTI89_C2247 NC_007946.1 2190362 2190625 R transposase complement(2190362..2190625) Escherichia coli UTI89 3994451 YP_541247.1 CDS UTI89_C2248 NC_007946.1 2190909 2191319 R hypothetical protein complement(2190909..2191319) Escherichia coli UTI89 3994452 YP_541248.1 CDS UTI89_C2249 NC_007946.1 2191307 2191708 R hypothetical protein complement(2191307..2191708) Escherichia coli UTI89 3994453 YP_541249.1 CDS UTI89_C2250 NC_007946.1 2191874 2192479 R hypothetical protein complement(2191874..2192479) Escherichia coli UTI89 3994454 YP_541250.1 CDS UTI89_C2251 NC_007946.1 2193083 2193259 R hypothetical protein complement(2193083..2193259) Escherichia coli UTI89 3994455 YP_541251.1 CDS UTI89_C2252 NC_007946.1 2193210 2193590 D hypothetical protein 2193210..2193590 Escherichia coli UTI89 3994456 YP_541252.1 CDS UTI89_C2253 NC_007946.1 2194023 2195219 D transposase 2194023..2195219 Escherichia coli UTI89 3994457 YP_541253.1 CDS UTI89_C2254 NC_007946.1 2195343 2195621 D hypothetical protein 2195343..2195621 Escherichia coli UTI89 3994458 YP_541254.1 CDS UTI89_C2255 NC_007946.1 2195709 2196317 D hypothetical protein 2195709..2196317 Escherichia coli UTI89 3994459 YP_541255.1 CDS UTI89_C2256 NC_007946.1 2196746 2197006 D hypothetical protein 2196746..2197006 Escherichia coli UTI89 3994460 YP_541256.1 CDS UTI89_C2257 NC_007946.1 2197343 2198125 R transposase/IS protein complement(2197343..2198125) Escherichia coli UTI89 3994461 YP_541257.1 CDS UTI89_C2258 NC_007946.1 2198122 2199144 R transposase complement(2198122..2199144) Escherichia coli UTI89 3992392 YP_541258.1 CDS UTI89_C2259 NC_007946.1 2199197 2199469 D transposase 2199197..2199469 Escherichia coli UTI89 3992393 YP_541259.1 CDS UTI89_C2260 NC_007946.1 2199695 2200072 R hypothetical protein complement(2199695..2200072) Escherichia coli UTI89 3992394 YP_541260.1 CDS UTI89_C2261 NC_007946.1 2200641 2201813 D hypothetical protein 2200641..2201813 Escherichia coli UTI89 3992395 YP_541261.1 CDS UTI89_C2262 NC_007946.1 2202344 2202601 R hypothetical protein complement(2202344..2202601) Escherichia coli UTI89 3992396 YP_541262.1 CDS UTI89_C2263 NC_007946.1 2202655 2203422 R ABC transporter complement(2202655..2203422) Escherichia coli UTI89 3992397 YP_541263.1 CDS UTI89_C2264 NC_007946.1 2203419 2204477 R ABC transporter complement(2203419..2204477) Escherichia coli UTI89 3992398 YP_541264.1 CDS UTI89_C2265 NC_007946.1 2204496 2205488 R hypothetical protein complement(2204496..2205488) Escherichia coli UTI89 3992399 YP_541265.1 CDS UTI89_C2266 NC_007946.1 2205496 2207661 R TonB dependent receptor complement(2205496..2207661) Escherichia coli UTI89 3992400 YP_541266.1 CDS UTI89_C2267 NC_007946.1 2208090 2208524 D hypothetical protein 2208090..2208524 Escherichia coli UTI89 3992401 YP_541267.1 CDS UTI89_C2268 NC_007946.1 2208742 2211126 D hypothetical protein 2208742..2211126 Escherichia coli UTI89 3992402 YP_541268.1 CDS UTI89_C2269 NC_007946.1 2211123 2212028 D hypothetical protein 2211123..2212028 Escherichia coli UTI89 3992403 YP_541269.1 CDS UTI89_C2270 NC_007946.1 2212025 2213095 D hypothetical protein 2212025..2213095 Escherichia coli UTI89 3992404 YP_541270.1 CDS UTI89_C2271 NC_007946.1 2213123 2213908 D hypothetical protein 2213123..2213908 Escherichia coli UTI89 3992405 YP_541271.1 CDS UTI89_C2272 NC_007946.1 2213924 2214334 D hypothetical protein 2213924..2214334 Escherichia coli UTI89 3992406 YP_541272.1 CDS yafZ2 NC_007946.1 2214555 2215376 D hypothetical protein 2214555..2215376 Escherichia coli UTI89 3992407 YP_541273.1 CDS UTI89_C2274 NC_007946.1 2214561 2215469 R hypothetical protein complement(2214561..2215469) Escherichia coli UTI89 3992408 YP_541274.1 CDS yafX2 NC_007946.1 2215567 2216112 D hypothetical protein 2215567..2216112 Escherichia coli UTI89 3992409 YP_541275.1 CDS yeeS1 NC_007946.1 2216127 2216603 D hypothetical protein 2216127..2216603 Escherichia coli UTI89 3992410 YP_541276.1 CDS yeeT1 NC_007946.1 2216672 2216893 D hypothetical protein 2216672..2216893 Escherichia coli UTI89 3992372 YP_541277.1 CDS yeeU1 NC_007946.1 2216967 2217335 D hypothetical protein 2216967..2217335 Escherichia coli UTI89 3992373 YP_541278.1 CDS yeeV1 NC_007946.1 2217424 2217798 D hypothetical protein 2217424..2217798 Escherichia coli UTI89 3992374 YP_541279.1 CDS yeeW1 NC_007946.1 2217795 2217989 D hypothetical protein 2217795..2217989 Escherichia coli UTI89 3992375 YP_541280.1 CDS UTI89_C2281 NC_007946.1 2218430 2218786 D hypothetical protein 2218430..2218786 Escherichia coli UTI89 3992376 YP_541281.1 CDS yeeX NC_007946.1 2218887 2219282 R hypothetical protein complement(2218887..2219282) Escherichia coli UTI89 3992377 YP_541282.1 CDS yeeA NC_007946.1 2219388 2220446 R hypothetical protein complement(2219388..2220446) Escherichia coli UTI89 3992378 YP_541283.1 CDS sbmC NC_007946.1 2220644 2221117 R DNA gyrase inhibitor complement(2220644..2221117) Escherichia coli UTI89 3992379 YP_541284.2 CDS sbcB NC_007946.1 2222610 2224037 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2222610..2224037 Escherichia coli UTI89 3992380 YP_541285.1 CDS yeeF NC_007946.1 2224111 2225475 R transport protein YeeF complement(2224111..2225475) Escherichia coli UTI89 3992381 YP_541286.1 CDS UTI89_C2287 NC_007946.1 2225651 2225788 R hypothetical protein complement(2225651..2225788) Escherichia coli UTI89 3992382 YP_541287.1 CDS yeeY NC_007946.1 2225736 2226686 R transcriptional regulator YeeY complement(2225736..2226686) Escherichia coli UTI89 3992383 YP_541288.1 CDS UTI89_C2289 NC_007946.1 2226711 2227535 R protein YeeZ complement(2226711..2227535) Escherichia coli UTI89 3992384 YP_541289.1 CDS UTI89_C2290 NC_007946.1 2227618 2227872 R hypothetical protein complement(2227618..2227872) Escherichia coli UTI89 3992385 YP_541290.2 CDS yefM NC_007946.1 2227869 2228120 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2227869..2228120) Escherichia coli UTI89 3992386 YP_541291.1 CDS hisG NC_007946.1 2228599 2229498 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2228599..2229498 Escherichia coli UTI89 3992387 YP_541292.1 CDS hisD NC_007946.1 2229495 2230808 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2229495..2230808 Escherichia coli UTI89 3992388 YP_541293.1 CDS hisC NC_007946.1 2230805 2231875 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2230805..2231875 Escherichia coli UTI89 3992389 YP_541294.1 CDS hisB NC_007946.1 2231872 2232942 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2231872..2232942 Escherichia coli UTI89 3992390 YP_541295.1 CDS hisH NC_007946.1 2232942 2233532 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2232942..2233532 Escherichia coli UTI89 3992391 YP_541296.1 CDS hisA NC_007946.1 2233529 2234269 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2233529..2234269 Escherichia coli UTI89 3990900 YP_541297.1 CDS hisF NC_007946.1 2234251 2235027 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2234251..2235027 Escherichia coli UTI89 3990901 YP_541298.1 CDS hisI NC_007946.1 2235021 2235632 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2235021..2235632 Escherichia coli UTI89 3990902 YP_541299.1 CDS cld NC_007946.1 2235818 2236831 R regulator of length of O-antigen component of lipopolysaccharide chains complement(2235818..2236831) Escherichia coli UTI89 3990903 YP_541300.1 CDS ugd NC_007946.1 2236941 2238107 R UDP-glucose 6-dehydrogenase complement(2236941..2238107) Escherichia coli UTI89 3990904 YP_541301.1 CDS gnd NC_007946.1 2238354 2239760 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2238354..2239760) Escherichia coli UTI89 3990905 YP_541302.1 CDS wbgM NC_007946.1 2239903 2241006 R galactosyltransferase WbgM complement(2239903..2241006) Escherichia coli UTI89 3990906 YP_541303.1 CDS wbdM NC_007946.1 2241348 2242454 R glycosyltransferase WbdM complement(2241348..2242454) Escherichia coli UTI89 3990907 YP_541304.1 CDS UTI89_C2305 NC_007946.1 2242451 2243239 R glycosyltransferase complement(2242451..2243239) Escherichia coli UTI89 3990908 YP_541305.1 CDS wciP NC_007946.1 2243236 2244171 R rhamnosyl transferase complement(2243236..2244171) Escherichia coli UTI89 3990909 YP_541306.1 CDS UTI89_C2307 NC_007946.1 2244153 2245343 R bacteriophage HK620 O-antigen modification protein complement(2244153..2245343) Escherichia coli UTI89 3990910 YP_541307.1 CDS rfbE NC_007946.1 2245400 2246647 R O-antigen transporter complement(2245400..2246647) Escherichia coli UTI89 3990911 YP_541308.1 CDS rfbC NC_007946.1 2246644 2247201 R dTDP-4-dehydrorhamnose 3,5-epimerase complement(2246644..2247201) Escherichia coli UTI89 3990912 YP_541309.1 CDS rfbA NC_007946.1 2247209 2248084 R glucose-1-phosphate thymidylyltransferase complement(2247209..2248084) Escherichia coli UTI89 3990913 YP_541310.1 CDS rfbD NC_007946.1 2248142 2249041 R with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase complement(2248142..2249041) Escherichia coli UTI89 3990914 YP_541311.1 CDS rfbB NC_007946.1 2249041 2250126 R NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose 4,6 dehydratase complement(2249041..2250126) Escherichia coli UTI89 3990915 YP_541312.1 CDS UTI89_C2313 NC_007946.1 2250199 2250444 D hypothetical protein 2250199..2250444 Escherichia coli UTI89 3990916 YP_541313.1 CDS galF NC_007946.1 2250499 2251404 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase complement(2250499..2251404) Escherichia coli UTI89 3990917 YP_541314.1 CDS wcaM NC_007946.1 2251567 2252961 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2251567..2252961) Escherichia coli UTI89 3990918 YP_541315.1 CDS wcaL NC_007946.1 2252972 2254192 R colanic acid biosynthesis glycosyltransferase complement(2252972..2254192) Escherichia coli UTI89 3990861 YP_541316.1 CDS wcaK NC_007946.1 2254189 2255469 R pyruvyl transferase complement(2254189..2255469) Escherichia coli UTI89 3990862 YP_541317.1 CDS UTI89_C2318 NC_007946.1 2255816 2256127 R ribonucleoside diphosphage reductase 1 subunit beta, B2 complement(2255816..2256127) Escherichia coli UTI89 3990863 YP_541318.1 CDS wzxC NC_007946.1 2256132 2257610 R colanic acid exporter complement(2256132..2257610) Escherichia coli UTI89 3990864 YP_541319.1 CDS wcaJ NC_007946.1 2257612 2259006 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2257612..2259006) Escherichia coli UTI89 3990865 YP_541320.1 CDS cpsG NC_007946.1 2259060 2260478 R phosphomannomutase complement(2259060..2260478) Escherichia coli UTI89 3990866 YP_541321.1 CDS UTI89_C2322 NC_007946.1 2260456 2260614 D hypothetical protein 2260456..2260614 Escherichia coli UTI89 3990867 YP_541322.1 CDS cpsB NC_007946.1 2260623 2262059 R mannose-1-phosphate guanylyltransferase complement(2260623..2262059) Escherichia coli UTI89 3990868 YP_541323.1 CDS wcaI NC_007946.1 2262062 2263285 R glycosyl transferase complement(2262062..2263285) Escherichia coli UTI89 3990869 YP_541324.1 CDS wcaH NC_007946.1 2263282 2263764 R mannose-1-phosphate guanylyltransferase complement(2263282..2263764) Escherichia coli UTI89 3990870 YP_541325.1 CDS wcaG NC_007946.1 2263764 2264729 R GDP-fucose synthetase chain A complement(2263764..2264729) Escherichia coli UTI89 3990871 YP_541326.1 CDS gmd NC_007946.1 2264732 2265853 R subunit of GDP-mannose 4,6-dehydratase complement(2264732..2265853) Escherichia coli UTI89 3990872 YP_541327.1 CDS wcaF NC_007946.1 2265880 2266428 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2265880..2266428) Escherichia coli UTI89 3990873 YP_541328.1 CDS wcaE NC_007946.1 2266444 2267190 R glycosyl transferase complement(2266444..2267190) Escherichia coli UTI89 3990874 YP_541329.1 CDS wcaD NC_007946.1 2267271 2268563 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2267271..2268563) Escherichia coli UTI89 3990875 YP_541330.1 CDS wcaC NC_007946.1 2268466 2269683 R glycosyl transferase complement(2268466..2269683) Escherichia coli UTI89 3990876 YP_541331.1 CDS wcaB NC_007946.1 2269680 2270168 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2269680..2270168) Escherichia coli UTI89 3990877 YP_541332.1 CDS wcaA NC_007946.1 2270171 2271010 R glycosyl transferase complement(2270171..2271010) Escherichia coli UTI89 3990878 YP_541333.2 CDS UTI89_C2334 NC_007946.1 2271139 2273301 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2271139..2273301) Escherichia coli UTI89 3990879 YP_541334.1 CDS wzb NC_007946.1 2273304 2273747 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2273304..2273747) Escherichia coli UTI89 3990880 YP_541335.1 CDS wza NC_007946.1 2273753 2274892 R polysaccharide export protein complement(2273753..2274892) Escherichia coli UTI89 3990749 YP_541336.1 CDS UTI89_C2337 NC_007946.1 2275484 2277133 D transport protein 2275484..2277133 Escherichia coli UTI89 3990750 YP_541337.1 CDS UTI89_C2338 NC_007946.1 2277208 2277546 D hypothetical protein 2277208..2277546 Escherichia coli UTI89 3990751 YP_541338.1 CDS UTI89_C2339 NC_007946.1 2277536 2277826 D hypothetical protein 2277536..2277826 Escherichia coli UTI89 3990752 YP_541339.1 CDS asmA NC_007946.1 2277879 2279732 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2277879..2279732) Escherichia coli UTI89 3990753 YP_541340.1 CDS dcd NC_007946.1 2279754 2280335 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2279754..2280335) Escherichia coli UTI89 3990754 YP_541341.1 CDS udk NC_007946.1 2280427 2281131 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2280427..2281131) Escherichia coli UTI89 3990755 YP_541342.1 CDS yegE NC_007946.1 2281386 2284703 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2281386..2284703 Escherichia coli UTI89 3990756 YP_541343.1 CDS alkA NC_007946.1 2284814 2285662 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase complement(2284814..2285662) Escherichia coli UTI89 3990757 YP_541344.2 CDS yegD NC_007946.1 2285796 2287148 D chaperone 2285796..2287148 Escherichia coli UTI89 3990758 YP_541345.1 CDS yegI NC_007946.1 2287161 2289110 R hypothetical protein complement(2287161..2289110) Escherichia coli UTI89 3990759 YP_541346.1 CDS yegK NC_007946.1 2289098 2289859 R hypothetical protein complement(2289098..2289859) Escherichia coli UTI89 3990760 YP_541347.1 CDS yegL NC_007946.1 2289856 2290515 R hypothetical protein complement(2289856..2290515) Escherichia coli UTI89 3990761 YP_541348.2 CDS yegM NC_007946.1 2291396 2292643 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2291396..2292643 Escherichia coli UTI89 3990762 YP_541349.1 CDS yegN NC_007946.1 2292643 2295765 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2292643..2295765 Escherichia coli UTI89 3990763 YP_541350.1 CDS yegO NC_007946.1 2295766 2298843 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2295766..2298843 Escherichia coli UTI89 3990764 YP_541351.1 CDS yegB NC_007946.1 2298844 2300259 D multidrug efflux system protein MdtE 2298844..2300259 Escherichia coli UTI89 3990765 YP_541352.1 CDS baeS NC_007946.1 2300256 2301659 D signal transduction histidine-protein kinase BaeS 2300256..2301659 Escherichia coli UTI89 3990766 YP_541353.1 CDS baeR NC_007946.1 2301656 2302378 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2301656..2302378 Escherichia coli UTI89 3990767 YP_541354.1 CDS yegP NC_007946.1 2302519 2302890 D hypothetical protein 2302519..2302890 Escherichia coli UTI89 3992103 YP_541355.1 CDS UTI89_C2356 NC_007946.1 2303015 2303629 R hypothetical protein complement(2303015..2303629) Escherichia coli UTI89 3992104 YP_541356.1 CDS UTI89_C2357 NC_007946.1 2303681 2305828 R hypothetical protein complement(2303681..2305828) Escherichia coli UTI89 3992105 YP_541357.1 CDS UTI89_C2358 NC_007946.1 2305800 2306516 R hypothetical protein complement(2305800..2306516) Escherichia coli UTI89 3992106 YP_541358.1 CDS UTI89_C2359 NC_007946.1 2306516 2307730 R hypothetical protein complement(2306516..2307730) Escherichia coli UTI89 3992107 YP_541359.1 CDS yegQ NC_007946.1 2308218 2309579 D hypothetical protein 2308218..2309579 Escherichia coli UTI89 3992108 YP_541360.1 CDS UTI89_C2361 NC_007946.1 2310079 2310456 R hypothetical protein complement(2310079..2310456) Escherichia coli UTI89 3992109 YP_541361.1 CDS UTI89_C2362 NC_007946.1 2310812 2311711 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2310812..2311711 Escherichia coli UTI89 3992110 YP_541362.1 CDS UTI89_C2363 NC_007946.1 2311793 2312572 R hypothetical protein complement(2311793..2312572) Escherichia coli UTI89 3992111 YP_541363.1 CDS gatD NC_007946.1 2312672 2313712 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2312672..2313712) Escherichia coli UTI89 3992112 YP_541364.1 CDS gatC NC_007946.1 2313760 2315115 R PTS system galactitol-specific transporter subunit IIC complement(2313760..2315115) Escherichia coli UTI89 3992113 YP_541365.1 CDS gatB NC_007946.1 2315119 2315403 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2315119..2315403) Escherichia coli UTI89 3992114 YP_541366.1 CDS gatA NC_007946.1 2315434 2315886 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2315434..2315886) Escherichia coli UTI89 3992115 YP_541367.1 CDS gatZ NC_007946.1 2315896 2317158 R tagatose 6-phosphate kinase GatZ complement(2315896..2317158) Escherichia coli UTI89 3992116 YP_541368.2 CDS gatY NC_007946.1 2317187 2318041 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2317187..2318041) Escherichia coli UTI89 3992117 YP_541369.1 CDS UTI89_C2370 NC_007946.1 2318023 2318280 D hypothetical protein 2318023..2318280 Escherichia coli UTI89 3992118 YP_541370.2 CDS UTI89_C2371 NC_007946.1 2318270 2319322 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2318270..2319322) Escherichia coli UTI89 3992119 YP_541371.1 CDS yegT NC_007946.1 2319579 2320856 D nucleoside transporter YegT 2319579..2320856 Escherichia coli UTI89 3992120 YP_541372.1 CDS UTI89_C2373 NC_007946.1 2320853 2321857 D hypothetical protein 2320853..2321857 Escherichia coli UTI89 3992121 YP_541373.1 CDS yegV NC_007946.1 2321854 2322819 D sugar kinase YegV 2321854..2322819 Escherichia coli UTI89 3992122 YP_541374.1 CDS yegW NC_007946.1 2322793 2323539 R transcriptional regulator complement(2322793..2323539) Escherichia coli UTI89 3989645 YP_541375.1 CDS yegX NC_007946.1 2323591 2324418 R hypothetical protein complement(2323591..2324418) Escherichia coli UTI89 3989646 YP_541376.1 CDS thiD NC_007946.1 2324474 2325274 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2324474..2325274) Escherichia coli UTI89 3989647 YP_541377.1 CDS thiM NC_007946.1 2325271 2326059 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2325271..2326059) Escherichia coli UTI89 3989648 YP_541378.1 CDS yohL NC_007946.1 2326282 2326554 R hypothetical protein complement(2326282..2326554) Escherichia coli UTI89 3989649 YP_541379.1 CDS yohM NC_007946.1 2326675 2327499 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2326675..2327499 Escherichia coli UTI89 3989650 YP_541380.1 CDS yohN NC_007946.1 2327538 2328056 D hypothetical protein 2327538..2328056 Escherichia coli UTI89 3989651 YP_541381.1 CDS yehA NC_007946.1 2328138 2329172 R Yeh fimbiral adhesin YehA complement(2328138..2329172) Escherichia coli UTI89 3989652 YP_541382.1 CDS yehB NC_007946.1 2329188 2331683 R outer membrane usher protein YehB complement(2329188..2331683) Escherichia coli UTI89 3989653 YP_541383.1 CDS yehC NC_007946.1 2331684 2332358 R periplasmic chaperone YehC complement(2331684..2332358) Escherichia coli UTI89 3989654 YP_541384.1 CDS yehD NC_007946.1 2332439 2332981 R Yeh fimbriae subunit YehD complement(2332439..2332981) Escherichia coli UTI89 3989655 YP_541385.1 CDS yehE NC_007946.1 2333274 2333555 R hypothetical protein complement(2333274..2333555) Escherichia coli UTI89 3989656 YP_541386.2 CDS mrp NC_007946.1 2333818 2334927 R ATPase complement(2333818..2334927) Escherichia coli UTI89 3989657 YP_541387.1 CDS metG NC_007946.1 2335050 2337092 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2335050..2337092 Escherichia coli UTI89 3989658 YP_541388.1 CDS UTI89_C2389 NC_007946.1 2337233 2341021 D hypothetical protein 2337233..2341021 Escherichia coli UTI89 3989659 YP_541389.1 CDS yehI NC_007946.1 2341031 2344663 D hypothetical protein 2341031..2344663 Escherichia coli UTI89 3989660 YP_541390.1 CDS UTI89_C2391 NC_007946.1 2344724 2344909 D hypothetical protein 2344724..2344909 Escherichia coli UTI89 3989661 YP_541391.1 CDS yehL NC_007946.1 2345754 2346908 D hypothetical protein 2345754..2346908 Escherichia coli UTI89 3989662 YP_541392.1 CDS yehP NC_007946.1 2349121 2350320 D hypothetical protein 2349121..2350320 Escherichia coli UTI89 3989663 YP_541393.1 CDS yehQ NC_007946.1 2350317 2352320 D hypothetical protein 2350317..2352320 Escherichia coli UTI89 3989683 YP_541394.1 CDS yehR NC_007946.1 2352433 2352906 D lipoprotein YehR 2352433..2352906 Escherichia coli UTI89 3989684 YP_541395.1 CDS yehS NC_007946.1 2352947 2353474 R hypothetical protein complement(2352947..2353474) Escherichia coli UTI89 3989685 YP_541396.1 CDS yehT NC_007946.1 2353464 2354198 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2353464..2354198) Escherichia coli UTI89 3989686 YP_541397.1 CDS yehU NC_007946.1 2354180 2355880 R 2-component sensor protein complement(2354180..2355880) Escherichia coli UTI89 3989687 YP_541398.1 CDS yehV NC_007946.1 2356087 2356818 D transcriptional regulator 2356087..2356818 Escherichia coli UTI89 3989688 YP_541399.1 CDS UTI89_C2400 NC_007946.1 2356878 2356985 D hypothetical protein 2356878..2356985 Escherichia coli UTI89 3989689 YP_541400.1 CDS yehW NC_007946.1 2356966 2357697 R transport system permease complement(2356966..2357697) Escherichia coli UTI89 3989690 YP_541401.1 CDS yehX NC_007946.1 2357702 2358628 R ABC transporter ATP-binding protein complement(2357702..2358628) Escherichia coli UTI89 3989691 YP_541402.1 CDS yehY NC_007946.1 2358621 2359778 R ABC transporter permease complement(2358621..2359778) Escherichia coli UTI89 3989692 YP_541403.1 CDS yehZ NC_007946.1 2359785 2360702 R hypothetical protein complement(2359785..2360702) Escherichia coli UTI89 3989693 YP_541404.1 CDS UTI89_C2405 NC_007946.1 2360733 2360885 R hypothetical protein complement(2360733..2360885) Escherichia coli UTI89 3989694 YP_541405.1 CDS bglX NC_007946.1 2360892 2363189 R beta-D-glucoside glucohydrolase complement(2360892..2363189) Escherichia coli UTI89 3989695 YP_541406.2 CDS dld NC_007946.1 2363385 2365100 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2363385..2365100 Escherichia coli UTI89 3989696 YP_541407.1 CDS pbpG NC_007946.1 2365139 2366080 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2365139..2366080) Escherichia coli UTI89 3989697 YP_541408.1 CDS yohC NC_007946.1 2366245 2366856 R hypothetical protein complement(2366245..2366856) Escherichia coli UTI89 3989698 YP_541409.1 CDS yohD NC_007946.1 2366966 2367580 D hypothetical protein 2366966..2367580 Escherichia coli UTI89 3989699 YP_541410.1 CDS UTI89_C2411 NC_007946.1 2367700 2368461 R acetoin dehydrogenase complement(2367700..2368461) Escherichia coli UTI89 3989700 YP_541411.2 CDS yohG NC_007946.1 2368514 2369950 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2368514..2369950) Escherichia coli UTI89 3989701 YP_541412.1 CDS yohI NC_007946.1 2370645 2371661 R tRNA-dihydrouridine synthase C complement(2370645..2371661) Escherichia coli UTI89 3989702 YP_541413.1 CDS yohJ NC_007946.1 2371798 2372232 D hypothetical protein 2371798..2372232 Escherichia coli UTI89 3990461 YP_541414.1 CDS yohK NC_007946.1 2372229 2372924 D hypothetical protein 2372229..2372924 Escherichia coli UTI89 3990462 YP_541415.1 CDS cdd NC_007946.1 2373054 2373938 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2373054..2373938 Escherichia coli UTI89 3990463 YP_541416.1 CDS sanA NC_007946.1 2374088 2374807 D hypothetical protein 2374088..2374807 Escherichia coli UTI89 3990464 YP_541417.1 CDS UTI89_C2418 NC_007946.1 2374810 2375049 D hypothetical protein 2374810..2375049 Escherichia coli UTI89 3990465 YP_541418.1 CDS yeiT NC_007946.1 2375243 2376481 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2375243..2376481 Escherichia coli UTI89 3990466 YP_541419.1 CDS yeiA NC_007946.1 2376469 2377710 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2376469..2377710 Escherichia coli UTI89 3990467 YP_541420.1 CDS mglC NC_007946.1 2377953 2378963 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component complement(2377953..2378963) Escherichia coli UTI89 3990468 YP_541421.1 CDS mglA NC_007946.1 2378979 2380499 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2378979..2380499) Escherichia coli UTI89 3990469 YP_541422.1 CDS mglB NC_007946.1 2380560 2381558 R galactose-binding transport protein complement(2380560..2381558) Escherichia coli UTI89 3990470 YP_541423.1 CDS galS NC_007946.1 2381838 2382884 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2381838..2382884) Escherichia coli UTI89 3990471 YP_541424.1 CDS UTI89_C2425 NC_007946.1 2382868 2383071 D hypothetical protein 2382868..2383071 Escherichia coli UTI89 3990472 YP_541425.1 CDS UTI89_C2426 NC_007946.1 2383020 2384177 R hypothetical protein complement(2383020..2384177) Escherichia coli UTI89 3990473 YP_541426.1 CDS folE NC_007946.1 2384194 2384862 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2384194..2384862) Escherichia coli UTI89 3990474 YP_541427.1 CDS yeiG NC_007946.1 2385120 2385956 D hypothetical protein 2385120..2385956 Escherichia coli UTI89 3990475 YP_541428.1 CDS cirA NC_007946.1 2385988 2388060 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2385988..2388060) Escherichia coli UTI89 3990476 YP_541429.1 CDS lysP NC_007946.1 2388271 2389740 R lysine transporter complement(2388271..2389740) Escherichia coli UTI89 3990477 YP_541430.1 CDS UTI89_C2431 NC_007946.1 2389724 2389972 R hypothetical protein complement(2389724..2389972) Escherichia coli UTI89 3990478 YP_541431.1 CDS yeiE NC_007946.1 2389945 2390826 R DNA-binding transcriptional regulator complement(2389945..2390826) Escherichia coli UTI89 3990479 YP_541432.1 CDS yeiH NC_007946.1 2390925 2391974 D hypothetical protein 2390925..2391974 Escherichia coli UTI89 3990807 YP_541433.1 CDS nfo NC_007946.1 2392048 2392905 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2392048..2392905 Escherichia coli UTI89 3990808 YP_541434.1 CDS yeiI NC_007946.1 2392909 2393997 D hypothetical protein 2392909..2393997 Escherichia coli UTI89 3990809 YP_541435.1 CDS rihB NC_007946.1 2394265 2395206 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2394265..2395206) Escherichia coli UTI89 3990810 YP_541436.1 CDS yeiL NC_007946.1 2395336 2396034 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2395336..2396034 Escherichia coli UTI89 3990811 YP_541437.1 CDS yeiM NC_007946.1 2396101 2397351 R transport protein YeiM complement(2396101..2397351) Escherichia coli UTI89 3990812 YP_541438.1 CDS yeiN NC_007946.1 2397445 2398383 R hypothetical protein complement(2397445..2398383) Escherichia coli UTI89 3990813 YP_541439.1 CDS yeiC NC_007946.1 2398371 2399426 R hypothetical protein complement(2398371..2399426) Escherichia coli UTI89 3990814 YP_541440.1 CDS UTI89_C2441 NC_007946.1 2399528 2399950 D hypothetical protein 2399528..2399950 Escherichia coli UTI89 3990815 YP_541441.1 CDS fruA NC_007946.1 2399768 2401459 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC complement(2399768..2401459) Escherichia coli UTI89 3990816 YP_541442.1 CDS fruK NC_007946.1 2401476 2402414 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2401476..2402414) Escherichia coli UTI89 3990817 YP_541443.1 CDS UTI89_C2444 NC_007946.1 2402414 2403544 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2402414..2403544) Escherichia coli UTI89 3990818 YP_541444.1 CDS UTI89_C2445 NC_007946.1 2403709 2403840 D hypothetical protein 2403709..2403840 Escherichia coli UTI89 3990819 YP_541445.1 CDS yeiO NC_007946.1 2403911 2405092 D sugar efflux transporter B 2403911..2405092 Escherichia coli UTI89 3990820 YP_541446.1 CDS UTI89_C2447 NC_007946.1 2405089 2405277 R hypothetical protein complement(2405089..2405277) Escherichia coli UTI89 3990821 YP_541447.1 CDS yeiP NC_007946.1 2405243 2406070 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2405243..2406070 Escherichia coli UTI89 3990822 YP_541448.1 CDS yeiQ NC_007946.1 2406284 2407759 D oxidoreductase YeiQ 2406284..2407759 Escherichia coli UTI89 3990823 YP_541449.1 CDS yeiR NC_007946.1 2407877 2408863 D hypothetical protein 2407877..2408863 Escherichia coli UTI89 3990824 YP_541450.1 CDS UTI89_C2451 NC_007946.1 2408866 2409615 D hypothetical protein 2408866..2409615 Escherichia coli UTI89 3990825 YP_541451.1 CDS spr NC_007946.1 2410027 2410593 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2410027..2410593 Escherichia coli UTI89 3990826 YP_541452.1 CDS rtn NC_007946.1 2410774 2412330 D hypothetical protein 2410774..2412330 Escherichia coli UTI89 3990386 YP_541453.1 CDS yejA NC_007946.1 2412406 2414226 D hypothetical protein 2412406..2414226 Escherichia coli UTI89 3990387 YP_541454.1 CDS UTI89_C2455 NC_007946.1 2414227 2415321 D oligopeptide transport system permease OppB 2414227..2415321 Escherichia coli UTI89 3990388 YP_541455.1 CDS yejE NC_007946.1 2415321 2416346 D transport system permease 2415321..2416346 Escherichia coli UTI89 3990389 YP_541456.1 CDS yejF NC_007946.1 2416348 2417937 D ABC transporter ATP-binding protein 2416348..2417937 Escherichia coli UTI89 3990390 YP_541457.1 CDS yejG NC_007946.1 2417941 2418285 R hypothetical protein complement(2417941..2418285) Escherichia coli UTI89 3990391 YP_541458.1 CDS bcr NC_007946.1 2418619 2419809 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system complement(2418619..2419809) Escherichia coli UTI89 3990392 YP_541459.2 CDS rsuA NC_007946.1 2419837 2420532 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2419837..2420532) Escherichia coli UTI89 3990393 YP_541460.1 CDS yejH NC_007946.1 2420682 2422442 D hypothetical protein 2420682..2422442 Escherichia coli UTI89 3990394 YP_541462.1 CDS UTI89_C2463 NC_007946.1 2422552 2422983 R hypothetical protein complement(2422552..2422983) Escherichia coli UTI89 3990396 YP_541461.2 CDS rplY NC_007946.1 2422567 2422851 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2422567..2422851 Escherichia coli UTI89 3990395 YP_541463.1 CDS yejK NC_007946.1 2422990 2423997 R nucleoid-associated protein NdpA complement(2422990..2423997) Escherichia coli UTI89 3990397 YP_541464.1 CDS yejL NC_007946.1 2424179 2424406 D hypothetical protein 2424179..2424406 Escherichia coli UTI89 3990398 YP_541465.1 CDS yejM NC_007946.1 2424426 2426186 D sulfatase 2424426..2426186 Escherichia coli UTI89 3990399 YP_541466.1 CDS UTI89_C2468 NC_007946.1 2426439 2426594 R hypothetical protein complement(2426439..2426594) Escherichia coli UTI89 3990401 YP_541467.1 CDS yejO NC_007946.1 2427033 2427236 R outer membrane protein YejO complement(2427033..2427236) Escherichia coli UTI89 3990402 YP_541468.1 CDS UTI89_C2470 NC_007946.1 2427267 2427524 R hypothetical protein complement(2427267..2427524) Escherichia coli UTI89 3990403 YP_541469.1 CDS narP NC_007946.1 2427526 2428203 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2427526..2428203 Escherichia coli UTI89 3992293 YP_541470.1 CDS ccmH NC_007946.1 2428238 2429290 R cytochrome c-type biogenesis protein CcmH complement(2428238..2429290) Escherichia coli UTI89 3992294 YP_541471.1 CDS ccmG NC_007946.1 2429287 2429844 R disulfide oxidoreductase complement(2429287..2429844) Escherichia coli UTI89 3992295 YP_541472.1 CDS ccmF NC_007946.1 2429841 2431784 R cytochrome c-type biogenesis protein CcmF complement(2429841..2431784) Escherichia coli UTI89 3992296 YP_541473.1 CDS ccmE NC_007946.1 2431781 2432260 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2431781..2432260) Escherichia coli UTI89 3992297 YP_541474.1 CDS ccmD NC_007946.1 2432257 2432466 R heme exporter protein C complement(2432257..2432466) Escherichia coli UTI89 3992298 YP_541475.1 CDS ccmC NC_007946.1 2432463 2433224 R heme exporter protein C complement(2432463..2433224) Escherichia coli UTI89 3992299 YP_541476.1 CDS ccmB NC_007946.1 2433242 2433904 R heme exporter protein B complement(2433242..2433904) Escherichia coli UTI89 3992300 YP_541477.1 CDS ccmA NC_007946.1 2433901 2434524 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2433901..2434524) Escherichia coli UTI89 3992301 YP_541478.1 CDS napC NC_007946.1 2434537 2435139 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2434537..2435139) Escherichia coli UTI89 3992302 YP_541479.2 CDS napB NC_007946.1 2435149 2435598 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2435149..2435598) Escherichia coli UTI89 3992303 YP_541480.1 CDS napH NC_007946.1 2435595 2436458 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2435595..2436458) Escherichia coli UTI89 3992304 YP_541481.1 CDS napG NC_007946.1 2436445 2437140 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2436445..2437140) Escherichia coli UTI89 3992305 YP_541482.1 CDS napA NC_007946.1 2437147 2439633 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2437147..2439633) Escherichia coli UTI89 3992306 YP_541483.1 CDS napD NC_007946.1 2439630 2439893 R assembly protein for periplasmic nitrate reductase complement(2439630..2439893) Escherichia coli UTI89 3992307 YP_541484.1 CDS napF NC_007946.1 2439883 2440377 R Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein complement(2439883..2440377) Escherichia coli UTI89 3992308 YP_541485.1 CDS UTI89_C2487 NC_007946.1 2440477 2440650 D hypothetical protein 2440477..2440650 Escherichia coli UTI89 3992309 YP_541486.1 CDS UTI89_C2488 NC_007946.1 2440570 2440698 R hypothetical protein complement(2440570..2440698) Escherichia coli UTI89 3992310 YP_541487.1 CDS eco NC_007946.1 2440764 2441273 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2440764..2441273 Escherichia coli UTI89 3992311 YP_541488.1 CDS mqo NC_007946.1 2441423 2443069 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2441423..2443069) Escherichia coli UTI89 3992312 YP_541489.1 CDS yojI NC_007946.1 2443287 2444930 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding protein complement(2443287..2444930) Escherichia coli UTI89 3992274 YP_541490.1 CDS alkB NC_007946.1 2445006 2445656 R AlkB repair system protein for alkylated DNA and RNA complement(2445006..2445656) Escherichia coli UTI89 3992275 YP_541491.1 CDS ada NC_007946.1 2445656 2446720 R Ada transcriptional dual regulator / O-6-methylguanine-DNA methyltransferase complement(2445656..2446720) Escherichia coli UTI89 3992276 YP_541492.1 CDS UTI89_C2494 NC_007946.1 2446454 2446672 D hypothetical protein 2446454..2446672 Escherichia coli UTI89 3992277 YP_541493.1 CDS apbE NC_007946.1 2446794 2447849 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2446794..2447849) Escherichia coli UTI89 3992278 YP_541494.1 CDS UTI89_C2496 NC_007946.1 2447901 2448959 D hypothetical protein 2447901..2448959 Escherichia coli UTI89 3992279 YP_541495.1 CDS ompC NC_007946.1 2447961 2449052 R allows for ions and hydrophilic solutes to cross the outer membrane; porin complement(2447961..2449052) Escherichia coli UTI89 3992280 YP_541496.1 CDS yojN NC_007946.1 2449791 2452463 D phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2449791..2452463 Escherichia coli UTI89 3992281 YP_541497.1 CDS rcsB NC_007946.1 2452435 2453130 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2452435..2453130 Escherichia coli UTI89 3992282 YP_541498.1 CDS rcsC NC_007946.1 2453330 2456179 R hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2453330..2456179) Escherichia coli UTI89 3992283 YP_541499.1 CDS atoS NC_007946.1 2456334 2458172 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2456334..2458172 Escherichia coli UTI89 3992284 YP_541500.1 CDS atoC NC_007946.1 2458169 2459554 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2458169..2459554 Escherichia coli UTI89 3992285 YP_541501.1 CDS atoD NC_007946.1 2459750 2460412 D acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2459750..2460412 Escherichia coli UTI89 3992286 YP_541502.1 CDS atoA NC_007946.1 2460412 2461062 D acetate CoA-transferase subunit beta 2460412..2461062 Escherichia coli UTI89 3992287 YP_541503.1 CDS atoE NC_007946.1 2461059 2462381 D short-chain fatty acids transporter 2461059..2462381 Escherichia coli UTI89 3992288 YP_541504.1 CDS atoB NC_007946.1 2462412 2463596 D acetyl-CoA acetyltransferase 2462412..2463596 Escherichia coli UTI89 3992289 YP_541505.1 CDS yfaP NC_007946.1 2463670 2464446 R hypothetical protein complement(2463670..2464446) Escherichia coli UTI89 3992290 YP_541506.1 CDS yfaQ NC_007946.1 2464451 2466100 R hypothetical protein complement(2464451..2466100) Escherichia coli UTI89 3992291 YP_541507.1 CDS UTI89_C2509 NC_007946.1 2466101 2470630 R hypothetical protein complement(2466101..2470630) Escherichia coli UTI89 3992292 YP_541508.1 CDS yfaT NC_007946.1 2470639 2471289 R hypothetical protein complement(2470639..2471289) Escherichia coli UTI89 3992352 YP_541509.2 CDS yfaA NC_007946.1 2471259 2472947 R hypothetical protein complement(2471259..2472947) Escherichia coli UTI89 3992353 YP_541510.1 CDS gyrA NC_007946.1 2473096 2475723 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2473096..2475723) Escherichia coli UTI89 3992354 YP_541511.1 CDS ubiG NC_007946.1 2475870 2476592 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2475870..2476592 Escherichia coli UTI89 3992355 YP_541512.1 CDS yfaL NC_007946.1 2476732 2480496 R adhesin complement(2476732..2480496) Escherichia coli UTI89 3992356 YP_541513.1 CDS nrdA NC_007946.1 2481172 2483457 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2481172..2483457 Escherichia coli UTI89 3992357 YP_541514.1 CDS nrdB NC_007946.1 2483604 2484734 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2483604..2484734 Escherichia coli UTI89 3992358 YP_541515.1 CDS yfaE NC_007946.1 2484734 2484988 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2484734..2484988 Escherichia coli UTI89 3992359 YP_541516.1 CDS inaA NC_007946.1 2485042 2485692 R hypothetical protein complement(2485042..2485692) Escherichia coli UTI89 3992360 YP_541517.1 CDS glpQ NC_007946.1 2485895 2486971 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2485895..2486971) Escherichia coli UTI89 3992361 YP_541518.1 CDS glpT NC_007946.1 2486976 2488334 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2486976..2488334) Escherichia coli UTI89 3992362 YP_541519.1 CDS glpA NC_007946.1 2488607 2490235 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2488607..2490235 Escherichia coli UTI89 3992363 YP_541520.1 CDS glpB NC_007946.1 2490153 2491484 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2490153..2491484 Escherichia coli UTI89 3992364 YP_541521.2 CDS glpC NC_007946.1 2491481 2492671 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2491481..2492671 Escherichia coli UTI89 3992365 YP_541522.1 CDS UTI89_C2524 NC_007946.1 2492696 2492821 D hypothetical protein 2492696..2492821 Escherichia coli UTI89 3992366 YP_541523.1 CDS yfaD NC_007946.1 2492864 2493823 D hypothetical protein 2492864..2493823 Escherichia coli UTI89 3992367 YP_541524.1 CDS UTI89_C2526 NC_007946.1 2493836 2494021 D hypothetical protein 2493836..2494021 Escherichia coli UTI89 3992368 YP_541525.1 CDS yfaU NC_007946.1 2494062 2494865 R aldolase complement(2494062..2494865) Escherichia coli UTI89 3992369 YP_541526.1 CDS yfaV NC_007946.1 2494883 2496211 R transport protein YfaV complement(2494883..2496211) Escherichia coli UTI89 3992370 YP_541527.1 CDS yfaW NC_007946.1 2496229 2497446 R hypothetical protein complement(2496229..2497446) Escherichia coli UTI89 3992371 YP_541528.1 CDS yfaX NC_007946.1 2497449 2498231 R transcriptional regulator YfaX complement(2497449..2498231) Escherichia coli UTI89 3990977 YP_541529.1 CDS UTI89_C2531 NC_007946.1 2498451 2499653 R competence damage-inducible protein A complement(2498451..2499653) Escherichia coli UTI89 3990978 YP_541530.1 CDS yfaZ NC_007946.1 2499753 2500316 R hypothetical protein complement(2499753..2500316) Escherichia coli UTI89 3990979 YP_541531.1 CDS yfaO NC_007946.1 2500574 2500999 D Nudix hydrolase YfaO 2500574..2500999 Escherichia coli UTI89 3990980 YP_541532.1 CDS ais NC_007946.1 2501038 2501667 R Ais protein complement(2501038..2501667) Escherichia coli UTI89 3990981 YP_541533.2 CDS yfbE NC_007946.1 2501948 2503087 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2501948..2503087 Escherichia coli UTI89 3990982 YP_541534.1 CDS UTI89_C2536 NC_007946.1 2503091 2504059 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2503091..2504059 Escherichia coli UTI89 3990983 YP_541535.1 CDS yfbG NC_007946.1 2504059 2506041 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2504059..2506041 Escherichia coli UTI89 3990984 YP_541536.1 CDS yfbH NC_007946.1 2506038 2506928 D hypothetical protein 2506038..2506928 Escherichia coli UTI89 3990985 YP_541537.1 CDS arnT NC_007946.1 2506928 2508580 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2506928..2508580 Escherichia coli UTI89 3990986 YP_541538.1 CDS UTI89_C2540 NC_007946.1 2508577 2508912 D hypothetical protein 2508577..2508912 Escherichia coli UTI89 3990987 YP_541539.1 CDS yfbJ NC_007946.1 2508630 2509298 D hypothetical protein 2508630..2509298 Escherichia coli UTI89 3990988 YP_541540.1 CDS pmrD NC_007946.1 2509292 2509588 R polymyxin B resistance protein PmrD complement(2509292..2509588) Escherichia coli UTI89 3990989 YP_541541.1 CDS menE NC_007946.1 2509668 2511023 R O-succinylbenzoic acid--CoA ligase complement(2509668..2511023) Escherichia coli UTI89 3990990 YP_541542.1 CDS menC NC_007946.1 2511020 2511982 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2511020..2511982) Escherichia coli UTI89 3990991 YP_541543.1 CDS menB NC_007946.1 2511982 2512839 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2511982..2512839) Escherichia coli UTI89 3990992 YP_541544.1 CDS UTI89_C2546 NC_007946.1 2512171 2513004 D hypothetical protein 2512171..2513004 Escherichia coli UTI89 3990993 YP_541545.1 CDS yfbB NC_007946.1 2512854 2513612 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(2512854..2513612) Escherichia coli UTI89 3990994 YP_541546.1 CDS menD NC_007946.1 2513609 2515468 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2513609..2515468) Escherichia coli UTI89 3990995 YP_541547.1 CDS menF NC_007946.1 2515368 2516663 R menaquinone-specific isochorismate synthase complement(2515368..2516663) Escherichia coli UTI89 3991758 YP_541548.1 CDS elaB NC_007946.1 2516742 2517047 R hypothetical protein complement(2516742..2517047) Escherichia coli UTI89 3991759 YP_541549.1 CDS elaA NC_007946.1 2517102 2517563 R hypothetical protein complement(2517102..2517563) Escherichia coli UTI89 3991760 YP_541550.1 CDS elaC NC_007946.1 2517628 2518545 D member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2517628..2518545 Escherichia coli UTI89 3991761 YP_541551.1 CDS yfbK NC_007946.1 2518666 2520408 R hypothetical protein complement(2518666..2520408) Escherichia coli UTI89 3991762 YP_541552.1 CDS yfbL NC_007946.1 2520540 2521517 D aminopeptidase 2520540..2521517 Escherichia coli UTI89 3991763 YP_541553.1 CDS yfbM NC_007946.1 2521620 2522123 D hypothetical protein 2521620..2522123 Escherichia coli UTI89 3991764 YP_541554.1 CDS nuoN NC_007946.1 2522190 2523647 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2522190..2523647) Escherichia coli UTI89 3991765 YP_541555.1 CDS nuoM NC_007946.1 2523654 2525183 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2523654..2525183) Escherichia coli UTI89 3991766 YP_541556.1 CDS nuoL NC_007946.1 2525347 2527188 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2525347..2527188) Escherichia coli UTI89 3991767 YP_541557.1 CDS nuoK NC_007946.1 2527185 2527487 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2527185..2527487) Escherichia coli UTI89 3991768 YP_541558.1 CDS nuoJ NC_007946.1 2527484 2528038 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2527484..2528038) Escherichia coli UTI89 3991769 YP_541559.1 CDS nuoI NC_007946.1 2528050 2528592 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2528050..2528592) Escherichia coli UTI89 3991770 YP_541560.1 CDS nuoH NC_007946.1 2528607 2529584 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2528607..2529584) Escherichia coli UTI89 3991771 YP_541561.1 CDS nuoG NC_007946.1 2529581 2532313 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2529581..2532313) Escherichia coli UTI89 3991772 YP_541562.1 CDS nuoF NC_007946.1 2532360 2533697 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2532360..2533697) Escherichia coli UTI89 3991773 YP_541563.1 CDS nuoE NC_007946.1 2533694 2534194 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2533694..2534194) Escherichia coli UTI89 3991774 YP_541564.1 CDS nuoC NC_007946.1 2534197 2535999 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2534197..2535999) Escherichia coli UTI89 3991775 YP_541565.1 CDS UTI89_C2567 NC_007946.1 2536093 2536755 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2536093..2536755) Escherichia coli UTI89 3991776 YP_541566.1 CDS nuoA NC_007946.1 2536771 2537214 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2536771..2537214) Escherichia coli UTI89 3991777 YP_541567.1 CDS UTI89_C2569 NC_007946.1 2537361 2537630 R hypothetical protein complement(2537361..2537630) Escherichia coli UTI89 3993214 YP_541568.1 CDS lrhA NC_007946.1 2537844 2538782 R transcriptional regulator LrhA complement(2537844..2538782) Escherichia coli UTI89 3993215 YP_541569.1 CDS UTI89_C2571 NC_007946.1 2539022 2539276 D hypothetical protein 2539022..2539276 Escherichia coli UTI89 3993216 YP_541570.1 CDS UTI89_C2572 NC_007946.1 2539702 2540919 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2539702..2540919 Escherichia coli UTI89 3993217 YP_541571.1 CDS yfbR NC_007946.1 2541003 2541602 D hypothetical protein 2541003..2541602 Escherichia coli UTI89 3993218 YP_541572.1 CDS yfbS NC_007946.1 2541661 2543493 R transport protein complement(2541661..2543493) Escherichia coli UTI89 3993219 YP_541573.1 CDS yfbT NC_007946.1 2543580 2544230 R phosphatase complement(2543580..2544230) Escherichia coli UTI89 3993220 YP_541574.1 CDS UTI89_C2576 NC_007946.1 2544241 2544753 R hypothetical protein complement(2544241..2544753) Escherichia coli UTI89 3993221 YP_541575.1 CDS yfbV NC_007946.1 2544818 2545273 R hypothetical protein complement(2544818..2545273) Escherichia coli UTI89 3993222 YP_541576.1 CDS UTI89_C2578 NC_007946.1 2545342 2545473 R hypothetical protein complement(2545342..2545473) Escherichia coli UTI89 3993223 YP_541577.1 CDS UTI89_C2579 NC_007946.1 2545611 2546813 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2545611..2546813 Escherichia coli UTI89 3993224 YP_541578.1 CDS UTI89_C2580 NC_007946.1 2546816 2549086 R hypothetical protein complement(2546816..2549086) Escherichia coli UTI89 3993225 YP_541579.1 CDS pta NC_007946.1 2546888 2549032 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2546888..2549032 Escherichia coli UTI89 3993226 YP_541580.2 CDS yfcC NC_007946.1 2549222 2550742 D hypothetical protein 2549222..2550742 Escherichia coli UTI89 3993227 YP_541581.1 CDS UTI89_C2583 NC_007946.1 2550775 2551317 R regulator complement(2550775..2551317) Escherichia coli UTI89 3993228 YP_541582.1 CDS yfcE NC_007946.1 2551375 2551929 R phosphodiesterase complement(2551375..2551929) Escherichia coli UTI89 3993229 YP_541583.1 CDS yfcF NC_007946.1 2551982 2552626 R hypothetical protein complement(2551982..2552626) Escherichia coli UTI89 3993230 YP_541584.1 CDS yfcG NC_007946.1 2552762 2553409 D glutathione S-transferase 2552762..2553409 Escherichia coli UTI89 3993231 YP_541585.1 CDS folX NC_007946.1 2553466 2553828 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2553466..2553828 Escherichia coli UTI89 3993232 YP_541586.1 CDS yfcH NC_007946.1 2553849 2554742 D sugar nucleotide epimerase 2553849..2554742 Escherichia coli UTI89 3992716 YP_541587.1 CDS yfcI NC_007946.1 2554790 2555680 R hypothetical protein complement(2554790..2555680) Escherichia coli UTI89 3992717 YP_541588.1 CDS hisP NC_007946.1 2555876 2556649 R histidine/lysine/arginine/ornithine transporter subunit complement(2555876..2556649) Escherichia coli UTI89 3992718 YP_541589.1 CDS hisM NC_007946.1 2556657 2557373 R histidine transport system membrane protein M complement(2556657..2557373) Escherichia coli UTI89 3992719 YP_541590.1 CDS hisQ NC_007946.1 2557370 2558056 R histidine transport system permease hisQ complement(2557370..2558056) Escherichia coli UTI89 3992720 YP_541591.1 CDS hisJ NC_007946.1 2558146 2558928 R histidine-binding periplasmic protein of high-affinity histidine transport system complement(2558146..2558928) Escherichia coli UTI89 3992721 YP_541592.1 CDS argT NC_007946.1 2559149 2559931 R lysine-arginine-ornithine-binding periplasmic protein complement(2559149..2559931) Escherichia coli UTI89 3992722 YP_541593.1 CDS ubiX NC_007946.1 2560197 2560766 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2560197..2560766) Escherichia coli UTI89 3992723 YP_541594.1 CDS purF NC_007946.1 2560861 2562378 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2560861..2562378) Escherichia coli UTI89 3992724 YP_541595.1 CDS cvpA NC_007946.1 2562415 2562903 R membrane protein required for colicin V production; colicin V production protein complement(2562415..2562903) Escherichia coli UTI89 3992725 YP_541596.1 CDS UTI89_C2598 NC_007946.1 2563005 2563175 D hypothetical protein 2563005..2563175 Escherichia coli UTI89 3992726 YP_541597.2 CDS dedD NC_007946.1 2563435 2564097 R hypothetical protein complement(2563435..2564097) Escherichia coli UTI89 3992727 YP_541598.1 CDS folC NC_007946.1 2564087 2565355 R bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2564087..2565355) Escherichia coli UTI89 3992728 YP_541599.2 CDS accD NC_007946.1 2565425 2566339 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2565425..2566339) Escherichia coli UTI89 3992729 YP_541600.1 CDS dedA NC_007946.1 2566495 2567154 R hypothetical protein complement(2566495..2567154) Escherichia coli UTI89 3992730 YP_541601.1 CDS truA NC_007946.1 2567237 2568049 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2567237..2568049) Escherichia coli UTI89 3992731 YP_541602.1 CDS usg NC_007946.1 2568049 2569062 R semialdehyde dehydrogenase complement(2568049..2569062) Escherichia coli UTI89 3992732 YP_541603.1 CDS pdxB NC_007946.1 2569128 2570264 R erythronate-4-phosphate dehydrogenase complement(2569128..2570264) Escherichia coli UTI89 3992733 YP_541604.1 CDS flk NC_007946.1 2570363 2571358 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2570363..2571358 Escherichia coli UTI89 3992734 YP_541605.1 CDS yfcJ NC_007946.1 2571355 2572533 R hypothetical protein complement(2571355..2572533) Escherichia coli UTI89 3992735 YP_541606.1 CDS fabB NC_007946.1 2572798 2574018 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2572798..2574018) Escherichia coli UTI89 3991778 YP_541607.2 CDS mnmC NC_007946.1 2574177 2576183 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2574177..2576183 Escherichia coli UTI89 3991779 YP_541608.1 CDS yfcL NC_007946.1 2576304 2576582 R hypothetical protein complement(2576304..2576582) Escherichia coli UTI89 3991780 YP_541609.1 CDS yfcM NC_007946.1 2576616 2577164 R hypothetical protein complement(2576616..2577164) Escherichia coli UTI89 3991781 YP_541610.1 CDS yfcA NC_007946.1 2577164 2577973 R hypothetical protein complement(2577164..2577973) Escherichia coli UTI89 3991782 YP_541611.1 CDS mepA NC_007946.1 2577973 2578797 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2577973..2578797) Escherichia coli UTI89 3991783 YP_541612.1 CDS aroC NC_007946.1 2578801 2579889 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2578801..2579889) Escherichia coli UTI89 3991784 YP_541613.1 CDS prmB NC_007946.1 2579921 2581186 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2579921..2581186) Escherichia coli UTI89 3991785 YP_541614.1 CDS yfcN NC_007946.1 2581019 2581570 D hypothetical protein 2581019..2581570 Escherichia coli UTI89 3991786 YP_541615.1 CDS yfcO NC_007946.1 2581890 2582747 R fimbrial adhesin YfcO complement(2581890..2582747) Escherichia coli UTI89 3991787 YP_541616.1 CDS yfcP NC_007946.1 2582734 2583261 R Yfc fimbriae subunit YfcP complement(2582734..2583261) Escherichia coli UTI89 3991788 YP_541617.1 CDS yfcQ NC_007946.1 2583258 2583737 R Yfc fimbriae subunit YfcQ complement(2583258..2583737) Escherichia coli UTI89 3991789 YP_541618.1 CDS yfcR NC_007946.1 2583734 2584237 R Yfc fimbriae subunit YfcR complement(2583734..2584237) Escherichia coli UTI89 3991790 YP_541619.1 CDS yfcS NC_007946.1 2584254 2585006 R periplasmic chaperone YfcS complement(2584254..2585006) Escherichia coli UTI89 3991791 YP_541620.1 CDS yfcU NC_007946.1 2585026 2587680 R outer membrane usher YfcU complement(2585026..2587680) Escherichia coli UTI89 3991792 YP_541621.1 CDS yfcV NC_007946.1 2587548 2588297 R Yfc fimbriae subunit YfcV complement(2587548..2588297) Escherichia coli UTI89 3991793 YP_541622.1 CDS UTI89_C2624 NC_007946.1 2588863 2589348 R phosphohistidine phosphatase complement(2588863..2589348) Escherichia coli UTI89 3991794 YP_541623.1 CDS fadJ NC_007946.1 2589551 2591695 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2589551..2591695) Escherichia coli UTI89 3991795 YP_541624.1 CDS fadI NC_007946.1 2591695 2593005 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2591695..2593005) Escherichia coli UTI89 3991796 YP_541625.1 CDS yfcZ NC_007946.1 2593186 2593494 R hypothetical protein complement(2593186..2593494) Escherichia coli UTI89 3991797 YP_541626.1 CDS UTI89_C2628 NC_007946.1 2593555 2593806 R hypothetical protein complement(2593555..2593806) Escherichia coli UTI89 3991798 YP_541627.1 CDS fadL NC_007946.1 2593836 2595182 D sensitivity to phage T2; long-chain fatty acid outer membrane transporter 2593836..2595182 Escherichia coli UTI89 3991799 YP_541628.1 CDS vacJ NC_007946.1 2595240 2595995 R VacJ lipoprotein complement(2595240..2595995) Escherichia coli UTI89 3991800 YP_541629.1 CDS UTI89_C2631 NC_007946.1 2596021 2596191 R hypothetical protein complement(2596021..2596191) Escherichia coli UTI89 3991801 YP_541630.1 CDS yfdC NC_007946.1 2596289 2597221 D transport 2596289..2597221 Escherichia coli UTI89 3991802 YP_541631.1 CDS intC NC_007946.1 2597497 2598690 D prophage integrase 2597497..2598690 Escherichia coli UTI89 3991804 YP_541632.1 CDS UTI89_C2635 NC_007946.1 2598930 2599265 R hypothetical protein complement(2598930..2599265) Escherichia coli UTI89 3991805 YP_541633.1 CDS sia NC_007946.1 2599874 2602819 R endo-alpha-sialidase complement(2599874..2602819) Escherichia coli UTI89 3991806 YP_541634.1 CDS ant NC_007946.1 2602920 2603843 R antirepressor protein complement(2602920..2603843) Escherichia coli UTI89 3991807 YP_541635.1 CDS UTI89_C2638 NC_007946.1 2604353 2604610 D hypothetical protein 2604353..2604610 Escherichia coli UTI89 3991808 YP_541636.1 CDS mnt NC_007946.1 2604634 2604882 D regulatory protein 2604634..2604882 Escherichia coli UTI89 3991809 YP_541637.1 CDS UTI89_C2640 NC_007946.1 2604925 2605524 D hypothetical protein 2604925..2605524 Escherichia coli UTI89 3991810 YP_541638.1 CDS UTI89_C2641 NC_007946.1 2605509 2605928 D hypothetical protein 2605509..2605928 Escherichia coli UTI89 3991811 YP_541639.1 CDS hkcB NC_007946.1 2605951 2606274 D hypothetical protein 2605951..2606274 Escherichia coli UTI89 3991812 YP_541640.1 CDS UTI89_C2643 NC_007946.1 2606275 2608434 R bacteriophage HK620 gene 16-like; DNA transfer protein complement(2606275..2608434) Escherichia coli UTI89 3991813 YP_541641.1 CDS UTI89_C2644 NC_007946.1 2608434 2609783 R bacteriophage HK620 gene 20-like; DNA transfer protein complement(2608434..2609783) Escherichia coli UTI89 3991814 YP_541642.1 CDS UTI89_C2645 NC_007946.1 2609794 2610486 R bacteriophage HK620 gene 7-like; DNA transfer protein complement(2609794..2610486) Escherichia coli UTI89 3991892 YP_541643.1 CDS UTI89_C2646 NC_007946.1 2610489 2610944 R bacteriophage HK620 gene 14-like; head assembly protein complement(2610489..2610944) Escherichia coli UTI89 3991893 YP_541644.1 CDS UTI89_C2647 NC_007946.1 2610944 2611645 R bacteriophage HK620 gene 26-like; DNA stabilization protein complement(2610944..2611645) Escherichia coli UTI89 3991894 YP_541645.1 CDS UTI89_C2648 NC_007946.1 2611645 2613063 R bacteriophage HK620 gene 10-like; DNA stabilization protein complement(2611645..2613063) Escherichia coli UTI89 3991895 YP_541646.1 CDS UTI89_C2649 NC_007946.1 2613073 2613534 R hypothetical protein complement(2613073..2613534) Escherichia coli UTI89 3991896 YP_541647.1 CDS UTI89_C2650 NC_007946.1 2613515 2613742 R hypothetical protein complement(2613515..2613742) Escherichia coli UTI89 3991897 YP_541648.1 CDS UTI89_C2651 NC_007946.1 2613745 2614998 R hypothetical protein complement(2613745..2614998) Escherichia coli UTI89 3991898 YP_541649.1 CDS UTI89_C2652 NC_007946.1 2615017 2615910 R bacteriophage HK620 gene 8-like; scaffold protein complement(2615017..2615910) Escherichia coli UTI89 3991899 YP_541650.1 CDS UTI89_C2653 NC_007946.1 2616001 2618199 R bacteriophage HK620 gene 1-like; portal protein complement(2616001..2618199) Escherichia coli UTI89 3991900 YP_541651.1 CDS UTI89_C2654 NC_007946.1 2618201 2619616 R bacteriophage HK620 gene 2-like; terminase large subunit complement(2618201..2619616) Escherichia coli UTI89 3991901 YP_541652.1 CDS UTI89_C2655 NC_007946.1 2619613 2620053 R hypothetical protein complement(2619613..2620053) Escherichia coli UTI89 3991902 YP_541653.1 CDS hkbM NC_007946.1 2620056 2620298 R hypothetical protein complement(2620056..2620298) Escherichia coli UTI89 3991903 YP_541654.1 CDS UTI89_C2657 NC_007946.1 2620526 2621137 R hypothetical protein complement(2620526..2621137) Escherichia coli UTI89 3991904 YP_541655.1 CDS UTI89_C2658 NC_007946.1 2621274 2621426 R hypothetical protein complement(2621274..2621426) Escherichia coli UTI89 3991905 YP_541656.1 CDS UTI89_C2659 NC_007946.1 2621414 2621851 R hypothetical protein complement(2621414..2621851) Escherichia coli UTI89 3991906 YP_541657.1 CDS UTI89_C2660 NC_007946.1 2621848 2622324 R bacteriophage HK620 gene R-like; lysin complement(2621848..2622324) Escherichia coli UTI89 3991907 YP_541658.1 CDS UTI89_C2661 NC_007946.1 2622308 2622631 R bacteriophage HK620 gene S-like; holin complement(2622308..2622631) Escherichia coli UTI89 3991908 YP_541659.1 CDS UTI89_C2662 NC_007946.1 2622856 2623062 D hypothetical protein 2622856..2623062 Escherichia coli UTI89 3991909 YP_541660.1 CDS UTI89_C2663 NC_007946.1 2623228 2623746 R bacteriophage ST64T antitermination protein gp23 complement(2623228..2623746) Escherichia coli UTI89 3991910 YP_541661.1 CDS ninH NC_007946.1 2623743 2623931 R hypothetical protein complement(2623743..2623931) Escherichia coli UTI89 3991911 YP_541662.1 CDS rus NC_007946.1 2623928 2624290 R Holliday-junction resolvase complement(2623928..2624290) Escherichia coli UTI89 3991912 YP_541663.1 CDS hkbD NC_007946.1 2624287 2624577 R hypothetical protein complement(2624287..2624577) Escherichia coli UTI89 3991913 YP_541664.1 CDS roi NC_007946.1 2624577 2625299 R DNA-binding protein Roi complement(2624577..2625299) Escherichia coli UTI89 3991914 YP_541665.1 CDS UTI89_C2668 NC_007946.1 2625461 2625808 R hypothetical protein complement(2625461..2625808) Escherichia coli UTI89 3991915 YP_541666.1 CDS ninE2 NC_007946.1 2625811 2625987 R bacteriophage lambda nin 60-like protein complement(2625811..2625987) Escherichia coli UTI89 3991916 YP_541667.1 CDS ninB2 NC_007946.1 2625984 2626424 R hypothetical protein complement(2625984..2626424) Escherichia coli UTI89 3991917 YP_541668.1 CDS UTI89_C2671 NC_007946.1 2626604 2626702 R bacteriophage HK97 gp56 complement(2626604..2626702) Escherichia coli UTI89 3991918 YP_541669.1 CDS UTI89_C2672 NC_007946.1 2626699 2628075 R bacteriophage Nil2 gene P DnaB analogue complement(2626699..2628075) Escherichia coli UTI89 3991919 YP_541670.1 CDS UTI89_C2673 NC_007946.1 2628072 2628959 R hypothetical protein complement(2628072..2628959) Escherichia coli UTI89 3991920 YP_541671.1 CDS UTI89_C2674 NC_007946.1 2629022 2629294 R hypothetical protein complement(2629022..2629294) Escherichia coli UTI89 3991921 YP_541672.1 CDS UTI89_C2675 NC_007946.1 2629317 2629610 R bacteriophage 343 regulatory protein CII complement(2629317..2629610) Escherichia coli UTI89 3991922 YP_541673.1 CDS cro NC_007946.1 2629719 2629904 R Cro protein complement(2629719..2629904) Escherichia coli UTI89 3991923 YP_541674.1 CDS UTI89_C2677 NC_007946.1 2629985 2630635 D repressor protein 2629985..2630635 Escherichia coli UTI89 3991924 YP_541675.1 CDS UTI89_C2678 NC_007946.1 2630756 2631145 R hypothetical protein complement(2630756..2631145) Escherichia coli UTI89 3991925 YP_541676.1 CDS UTI89_C2679 NC_007946.1 2631157 2631456 D phage regulatory protein N 2631157..2631456 Escherichia coli UTI89 3991926 YP_541677.1 CDS ral NC_007946.1 2631535 2631735 D bacteriophage lambda restriction inhibitor protein ral 2631535..2631735 Escherichia coli UTI89 3991927 YP_541678.1 CDS UTI89_C2681 NC_007946.1 2631794 2632216 D hypothetical protein 2631794..2632216 Escherichia coli UTI89 3991928 YP_541679.1 CDS UTI89_C2682 NC_007946.1 2633400 2633531 D protease inhibitor FtsH 2633400..2633531 Escherichia coli UTI89 3991929 YP_541680.1 CDS kil2 NC_007946.1 2633516 2633668 D kil protein of bacteriophage HK97 2633516..2633668 Escherichia coli UTI89 3991930 YP_541681.1 CDS UTI89_C2684 NC_007946.1 2633665 2633823 D hypothetical protein 2633665..2633823 Escherichia coli UTI89 3991552 YP_541682.1 CDS UTI89_C2685 NC_007946.1 2633744 2633914 D hypothetical protein 2633744..2633914 Escherichia coli UTI89 3991553 YP_541683.1 CDS erf NC_007946.1 2633925 2634530 D bacteriophage HK97 gp40 2633925..2634530 Escherichia coli UTI89 3991554 YP_541684.1 CDS UTI89_C2687 NC_007946.1 2634530 2634913 D bacteriophage HK97 gp40 2634530..2634913 Escherichia coli UTI89 3991555 YP_541685.1 CDS hkaJ NC_007946.1 2634937 2635233 D hypothetical protein 2634937..2635233 Escherichia coli UTI89 3991556 YP_541686.1 CDS hkaH NC_007946.1 2635310 2635846 D hypothetical protein 2635310..2635846 Escherichia coli UTI89 3991557 YP_541687.1 CDS UTI89_C2690 NC_007946.1 2636144 2636716 D hypothetical protein 2636144..2636716 Escherichia coli UTI89 3991558 YP_541688.1 CDS UTI89_C2691 NC_007946.1 2636939 2637289 R hypothetical protein complement(2636939..2637289) Escherichia coli UTI89 3991559 YP_541689.1 CDS UTI89_C2692 NC_007946.1 2636993 2637277 D hypothetical protein 2636993..2637277 Escherichia coli UTI89 3991560 YP_541690.1 CDS UTI89_C2693 NC_007946.1 2637350 2637517 D hypothetical protein 2637350..2637517 Escherichia coli UTI89 3991561 YP_541691.1 CDS hkaC NC_007946.1 2637575 2637775 D hypothetical protein 2637575..2637775 Escherichia coli UTI89 3991562 YP_541692.1 CDS dsdC NC_007946.1 2637962 2638903 R regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC complement(2637962..2638903) Escherichia coli UTI89 3991563 YP_541693.1 CDS UTI89_C2696 NC_007946.1 2639115 2640452 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2639115..2640452 Escherichia coli UTI89 3991564 YP_541694.1 CDS dsdA NC_007946.1 2640470 2641798 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2640470..2641798 Escherichia coli UTI89 3991565 YP_541695.1 CDS emrY NC_007946.1 2641906 2643444 R multidrug resistance protein Y complement(2641906..2643444) Escherichia coli UTI89 3991566 YP_541696.1 CDS UTI89_C2699 NC_007946.1 2643131 2643469 D hypothetical protein 2643131..2643469 Escherichia coli UTI89 3991567 YP_541697.1 CDS emrK NC_007946.1 2643444 2644607 R multidrug resistance protein K complement(2643444..2644607) Escherichia coli UTI89 3991568 YP_541698.1 CDS evgA NC_007946.1 2645023 2645637 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2645023..2645637 Escherichia coli UTI89 3991569 YP_541699.1 CDS evgS NC_007946.1 2645642 2649235 D hybrid sensory histidine kinase in two-component regulatory system with EvgA 2645642..2649235 Escherichia coli UTI89 3991570 YP_541700.1 CDS yfdE NC_007946.1 2649291 2650475 R hypothetical protein complement(2649291..2650475) Escherichia coli UTI89 3989763 YP_541701.1 CDS yfdV NC_007946.1 2650510 2651454 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(2650510..2651454) Escherichia coli UTI89 3989764 YP_541702.1 CDS UTI89_C2705 NC_007946.1 2651524 2653218 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(2651524..2653218) Escherichia coli UTI89 3989765 YP_541703.1 CDS yfdW NC_007946.1 2653272 2654522 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2653272..2654522) Escherichia coli UTI89 3989766 YP_541704.1 CDS yfdX NC_007946.1 2655034 2655669 R hypothetical protein complement(2655034..2655669) Escherichia coli UTI89 3989767 YP_541705.1 CDS ypdI NC_007946.1 2655965 2656240 D hypothetical protein 2655965..2656240 Escherichia coli UTI89 3989768 YP_541706.1 CDS yfdY NC_007946.1 2656317 2656559 R hypothetical protein complement(2656317..2656559) Escherichia coli UTI89 3989769 YP_541707.1 CDS ddg NC_007946.1 2656846 2657832 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2656846..2657832 Escherichia coli UTI89 3989770 YP_541708.1 CDS UTI89_C2711 NC_007946.1 2658324 2659562 R aminotransferase complement(2658324..2659562) Escherichia coli UTI89 3989771 YP_541709.1 CDS ypdA NC_007946.1 2659939 2661636 D hypothetical protein 2659939..2661636 Escherichia coli UTI89 3989772 YP_541710.1 CDS ypdB NC_007946.1 2661633 2662388 D hypothetical protein 2661633..2662388 Escherichia coli UTI89 3989773 YP_541711.1 CDS ypdC NC_007946.1 2662401 2663258 D transcriptional regulator YpdC 2662401..2663258 Escherichia coli UTI89 3989774 YP_541712.1 CDS UTI89_C2715 NC_007946.1 2663261 2665756 R phosphoenolpyruvate-protein phosphotransferase ypdD complement(2663261..2665756) Escherichia coli UTI89 3989775 YP_541713.1 CDS ypdE NC_007946.1 2665781 2666818 R metalloprotein; exoaminopeptidase complement(2665781..2666818) Escherichia coli UTI89 3989776 YP_541714.1 CDS UTI89_C2717 NC_007946.1 2666818 2667903 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2666818..2667903) Escherichia coli UTI89 3989777 YP_541715.1 CDS UTI89_C2718 NC_007946.1 2667919 2669166 R transport protein complement(2667919..2669166) Escherichia coli UTI89 3989778 YP_541716.1 CDS UTI89_C2719 NC_007946.1 2669188 2669565 R PTS system IIB component YpdH complement(2669188..2669565) Escherichia coli UTI89 3989779 YP_541717.1 CDS glk NC_007946.1 2669733 2670698 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2669733..2670698) Escherichia coli UTI89 3989780 YP_541718.1 CDS yfeO NC_007946.1 2670902 2672158 D hypothetical protein 2670902..2672158 Escherichia coli UTI89 3989781 YP_541719.1 CDS ypeC NC_007946.1 2672273 2672599 D hypothetical protein 2672273..2672599 Escherichia coli UTI89 3989782 YP_541721.1 CDS mntH NC_007946.1 2672740 2673978 R manganese transport protein MntH complement(2672740..2673978) Escherichia coli UTI89 3991686 YP_541722.1 CDS nupC NC_007946.1 2674275 2675516 D nucleoside permease NupC 2674275..2675516 Escherichia coli UTI89 3991687 YP_541723.1 CDS yfeA NC_007946.1 2675566 2677815 R hypothetical protein complement(2675566..2677815) Escherichia coli UTI89 3991688 YP_541724.1 CDS yfeC NC_007946.1 2678373 2678732 D hypothetical protein 2678373..2678732 Escherichia coli UTI89 3991691 YP_541725.1 CDS yfeD NC_007946.1 2678734 2679126 D hypothetical protein 2678734..2679126 Escherichia coli UTI89 3991692 YP_541726.1 CDS gltX NC_007946.1 2679177 2680592 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2679177..2680592) Escherichia coli UTI89 3991693 YP_541727.1 CDS xapR NC_007946.1 2681359 2682258 R DNA-binding transcriptional activator XapR complement(2681359..2682258) Escherichia coli UTI89 3989901 YP_541728.1 CDS UTI89_C2737 NC_007946.1 2682284 2682442 R hypothetical protein complement(2682284..2682442) Escherichia coli UTI89 3989902 YP_541729.1 CDS xapB NC_007946.1 2682495 2683751 R xanthosine permease complement(2682495..2683751) Escherichia coli UTI89 3989903 YP_541730.1 CDS xapA NC_007946.1 2683812 2684645 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2683812..2684645) Escherichia coli UTI89 3989904 YP_541731.1 CDS yfeR NC_007946.1 2685697 2686623 R LysR family transcriptional regulator complement(2685697..2686623) Escherichia coli UTI89 3989905 YP_541732.1 CDS yfeH NC_007946.1 2686713 2687711 D cytochrome oxidase 2686713..2687711 Escherichia coli UTI89 3989906 YP_541733.1 CDS UTI89_C2742 NC_007946.1 2687708 2687926 R hypothetical protein complement(2687708..2687926) Escherichia coli UTI89 3989907 YP_541734.1 CDS ligA NC_007946.1 2687928 2689943 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2687928..2689943) Escherichia coli UTI89 3989908 YP_541735.1 CDS zipA NC_007946.1 2690014 2691063 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2690014..2691063) Escherichia coli UTI89 3989909 YP_541736.1 CDS algP NC_007946.1 2690481 2690786 D regulatory protein AlgP 2690481..2690786 Escherichia coli UTI89 3989910 YP_541737.1 CDS cysZ NC_007946.1 2691242 2692003 D role in sulfur assimilation; sulfate transport protein CysZ 2691242..2692003 Escherichia coli UTI89 3989911 YP_541738.1 CDS cysK NC_007946.1 2692188 2693159 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2692188..2693159 Escherichia coli UTI89 3989912 YP_541739.1 CDS UTI89_C2748 NC_007946.1 2693477 2693770 R hypothetical protein complement(2693477..2693770) Escherichia coli UTI89 3989913 YP_541740.1 CDS ptsH NC_007946.1 2693543 2693800 D PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 2693543..2693800 Escherichia coli UTI89 3989914 YP_541741.1 CDS ptsI NC_007946.1 2693845 2695572 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2693845..2695572 Escherichia coli UTI89 3989915 YP_541742.1 CDS crr NC_007946.1 2695613 2696122 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 2695613..2696122 Escherichia coli UTI89 3989916 YP_541743.1 CDS pdxK NC_007946.1 2696165 2697016 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2696165..2697016) Escherichia coli UTI89 3989917 YP_541744.1 CDS yfeK NC_007946.1 2697121 2697489 D hypothetical protein 2697121..2697489 Escherichia coli UTI89 3989918 YP_541745.1 CDS cysM NC_007946.1 2697492 2698403 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2697492..2698403) Escherichia coli UTI89 3989919 YP_541746.1 CDS cysA NC_007946.1 2698538 2699635 R sulfate/thiosulfate transporter subunit complement(2698538..2699635) Escherichia coli UTI89 3989743 YP_541747.1 CDS cysW NC_007946.1 2699625 2700500 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2699625..2700500) Escherichia coli UTI89 3989744 YP_541748.1 CDS cysU NC_007946.1 2700500 2701333 R sulfate/thiosulfate transporter subunit complement(2700500..2701333) Escherichia coli UTI89 3989745 YP_541749.1 CDS cysP NC_007946.1 2701333 2702349 R thiosulfate transporter subunit complement(2701333..2702349) Escherichia coli UTI89 3989746 YP_541750.1 CDS ucpA NC_007946.1 2702507 2703364 R short chain dehydrogenase complement(2702507..2703364) Escherichia coli UTI89 3989747 YP_541751.1 CDS murQ NC_007946.1 2703578 2704474 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 2703578..2704474 Escherichia coli UTI89 3989748 YP_541752.1 CDS murP NC_007946.1 2704478 2705902 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 2704478..2705902 Escherichia coli UTI89 3989749 YP_541753.1 CDS UTI89_C2762 NC_007946.1 2705922 2706065 R hypothetical protein complement(2705922..2706065) Escherichia coli UTI89 3989750 YP_541754.1 CDS UTI89_C2763 NC_007946.1 2706065 2706991 D hypothetical protein 2706065..2706991 Escherichia coli UTI89 3989751 YP_541755.1 CDS yfeX NC_007946.1 2706080 2707006 R hypothetical protein complement(2706080..2707006) Escherichia coli UTI89 3989752 YP_541756.1 CDS yfeY NC_007946.1 2707075 2707650 R hypothetical protein complement(2707075..2707650) Escherichia coli UTI89 3989753 YP_541757.1 CDS yfeZ NC_007946.1 2707711 2708166 R hypothetical protein complement(2707711..2708166) Escherichia coli UTI89 3989754 YP_541758.1 CDS ypeA NC_007946.1 2708147 2708683 R acetyltransferase complement(2708147..2708683) Escherichia coli UTI89 3989755 YP_541759.1 CDS amiA NC_007946.1 2708786 2709655 D N-acetylmuramoyl-L-alanine amidase 2708786..2709655 Escherichia coli UTI89 3989756 YP_541760.1 CDS hemF NC_007946.1 2709656 2710558 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2709656..2710558 Escherichia coli UTI89 3989757 YP_541761.1 CDS yfeG NC_007946.1 2710564 2711616 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2710564..2711616) Escherichia coli UTI89 3989758 YP_541762.1 CDS eutK NC_007946.1 2711662 2712168 R synonym: b2438, yffI; ethanolamine utilization protein EutK complement(2711662..2712168) Escherichia coli UTI89 3989759 YP_541763.1 CDS eutL NC_007946.1 2712175 2712834 R synonym: yffJ, b2439; ethanolamine utilization protein EutL complement(2712175..2712834) Escherichia coli UTI89 3989760 YP_541764.1 CDS eutC NC_007946.1 2712844 2713731 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2712844..2713731) Escherichia coli UTI89 3989761 YP_541765.1 CDS eutB NC_007946.1 2713752 2715113 R regulatory subunit of ethanolamine ammonia-lyase complement(2713752..2715113) Escherichia coli UTI89 3989762 YP_541766.1 CDS eutA NC_007946.1 2715125 2716528 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2715125..2716528) Escherichia coli UTI89 3990132 YP_541767.1 CDS eutH NC_007946.1 2716525 2717751 R synonym: yffU, b2452; ethanolamine utilization transport protein EutH complement(2716525..2717751) Escherichia coli UTI89 3990133 YP_541768.1 CDS eutG NC_007946.1 2717968 2719182 R synonym: yffV, b2453; ethanolamine utilization protein EutG iron-containing alcohol dehydrogenase complement(2717968..2719182) Escherichia coli UTI89 3990134 YP_541769.1 CDS eutJ NC_007946.1 2719145 2719981 R synonym: yffW, b2454; ethanolamine utilization protein EutJ complement(2719145..2719981) Escherichia coli UTI89 3990135 YP_541770.1 CDS eutE NC_007946.1 2719992 2721395 R synonym: yffX, b2455; ethanolamine utilization protein EutE acetaldehyde dehydrogenase complement(2719992..2721395) Escherichia coli UTI89 3990136 YP_541771.1 CDS eutN NC_007946.1 2721407 2721694 R synonym: yffY, b2456, cchB; detox protein complement(2721407..2721694) Escherichia coli UTI89 3990137 YP_541772.1 CDS eutM NC_007946.1 2721801 2722136 R synonym: yffZ, b2457, cchA; detox protein complement(2721801..2722136) Escherichia coli UTI89 3990138 YP_541773.1 CDS eutD NC_007946.1 2722133 2723149 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2722133..2723149) Escherichia coli UTI89 3990139 YP_541774.1 CDS eutT NC_007946.1 2723146 2723949 R ethanolamine utilization cobalamin adenosyltransferase complement(2723146..2723949) Escherichia coli UTI89 3990140 YP_541775.1 CDS eutQ NC_007946.1 2723946 2724647 R ethanolamine utilization protein EutQ complement(2723946..2724647) Escherichia coli UTI89 3990141 YP_541776.1 CDS eutP NC_007946.1 2724622 2725101 R ethanolamine utilization protein EutP complement(2724622..2725101) Escherichia coli UTI89 3990142 YP_541777.1 CDS eutS NC_007946.1 2725114 2725521 R ethanolamine utilization protein EutS complement(2725114..2725521) Escherichia coli UTI89 3990143 YP_541778.1 CDS maeB NC_007946.1 2725742 2728021 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2725742..2728021) Escherichia coli UTI89 3990144 YP_541779.1 CDS talA NC_007946.1 2728310 2729260 D synonym: b2464, G7294, alaT; transaldolase A 2728310..2729260 Escherichia coli UTI89 3990145 YP_541780.2 CDS tktB NC_007946.1 2729280 2731283 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2729280..2731283 Escherichia coli UTI89 3990146 YP_541781.1 CDS ypfG NC_007946.1 2731360 2732403 R hypothetical protein complement(2731360..2732403) Escherichia coli UTI89 3990147 YP_541782.1 CDS UTI89_C2791 NC_007946.1 2732297 2732428 R hypothetical protein complement(2732297..2732428) Escherichia coli UTI89 3990148 YP_541783.1 CDS UTI89_C2792 NC_007946.1 2732303 2732563 D hypothetical protein 2732303..2732563 Escherichia coli UTI89 3990149 YP_541784.1 CDS yffH NC_007946.1 2732529 2733131 R hypothetical protein complement(2732529..2733131) Escherichia coli UTI89 3990150 YP_541785.1 CDS aegA NC_007946.1 2733172 2735151 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(2733172..2735151) Escherichia coli UTI89 3990558 YP_541786.1 CDS narQ NC_007946.1 2735342 2737057 D nitrate/nitrite sensor protein NarQ 2735342..2737057 Escherichia coli UTI89 3990559 YP_541787.1 CDS acrD NC_007946.1 2737221 2740334 D synonym: b2470, yffA; aminoglycoside/multidrug efflux system 2737221..2740334 Escherichia coli UTI89 3990560 YP_541788.1 CDS yffB NC_007946.1 2740873 2741229 D hypothetical protein 2740873..2741229 Escherichia coli UTI89 3990561 YP_541789.1 CDS dapE NC_007946.1 2741233 2742360 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2741233..2742360 Escherichia coli UTI89 3990562 YP_541790.1 CDS UTI89_C2799 NC_007946.1 2742388 2742588 D hypothetical protein 2742388..2742588 Escherichia coli UTI89 3990563 YP_541791.2 CDS ypfH NC_007946.1 2742669 2743367 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(2742669..2743367) Escherichia coli UTI89 3990564 YP_541792.1 CDS ypfI NC_007946.1 2743441 2745456 R hypothetical protein complement(2743441..2745456) Escherichia coli UTI89 3990565 YP_541793.1 CDS ypfJ NC_007946.1 2745471 2746334 R hypothetical protein complement(2745471..2746334) Escherichia coli UTI89 3990566 YP_541794.1 CDS purC NC_007946.1 2746502 2747224 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2746502..2747224) Escherichia coli UTI89 3990567 YP_541795.1 CDS nlpB NC_007946.1 2747428 2748465 R lipoprotein complement(2747428..2748465) Escherichia coli UTI89 3990568 YP_541796.1 CDS dapA NC_007946.1 2748479 2749375 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2748479..2749375) Escherichia coli UTI89 3990569 YP_541797.2 CDS gcvR NC_007946.1 2749503 2750075 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2749503..2750075 Escherichia coli UTI89 3990570 YP_541798.1 CDS bcp NC_007946.1 2750075 2750545 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2750075..2750545 Escherichia coli UTI89 3990571 YP_541799.1 CDS perM NC_007946.1 2750644 2751705 R permease PerM complement(2750644..2751705) Escherichia coli UTI89 3990572 YP_541800.1 CDS UTI89_C2809 NC_007946.1 2751736 2751912 D hypothetical protein 2751736..2751912 Escherichia coli UTI89 3990573 YP_541801.1 CDS yfgC NC_007946.1 2751918 2753381 D hypothetical protein 2751918..2753381 Escherichia coli UTI89 3990574 YP_541802.1 CDS yfgD NC_007946.1 2753402 2753761 D oxidoreductase 2753402..2753761 Escherichia coli UTI89 3990575 YP_541803.1 CDS yfgE NC_007946.1 2753899 2754645 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2753899..2754645) Escherichia coli UTI89 3990576 YP_541804.1 CDS uraA NC_007946.1 2754695 2756026 R uracil transporter complement(2754695..2756026) Escherichia coli UTI89 3990577 YP_541805.1 CDS upp NC_007946.1 2756070 2756723 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2756070..2756723) Escherichia coli UTI89 3992162 YP_541806.1 CDS purM NC_007946.1 2757020 2758057 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2757020..2758057 Escherichia coli UTI89 3992163 YP_541807.1 CDS purN NC_007946.1 2758057 2758695 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2758057..2758695 Escherichia coli UTI89 3992164 YP_541808.1 CDS ppk NC_007946.1 2758861 2760933 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2758861..2760933 Escherichia coli UTI89 3992165 YP_541809.1 CDS ppx NC_007946.1 2760938 2762479 D exopolyphosphatase 2760938..2762479 Escherichia coli UTI89 3992166 YP_541810.1 CDS yfgF NC_007946.1 2762518 2764761 R hypothetical protein complement(2762518..2764761) Escherichia coli UTI89 3992167 YP_541811.1 CDS UTI89_C2820 NC_007946.1 2764943 2765095 R hypothetical protein complement(2764943..2765095) Escherichia coli UTI89 3992168 YP_541812.1 CDS UTI89_C2821 NC_007946.1 2764978 2765268 R hypothetical protein complement(2764978..2765268) Escherichia coli UTI89 3992169 YP_541813.1 CDS UTI89_C2822 NC_007946.1 2765113 2765304 D hypothetical protein 2765113..2765304 Escherichia coli UTI89 3992170 YP_541814.1 CDS yfgH NC_007946.1 2765615 2766133 D outer membrane lipoprotein 2765615..2766133 Escherichia coli UTI89 3992171 YP_541815.1 CDS yfgI NC_007946.1 2766149 2766688 D hypothetical protein 2766149..2766688 Escherichia coli UTI89 3992172 YP_541816.1 CDS guaA NC_007946.1 2766782 2768359 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2766782..2768359) Escherichia coli UTI89 3992173 YP_541817.1 CDS guaB NC_007946.1 2768428 2769963 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2768428..2769963) Escherichia coli UTI89 3992174 YP_541818.1 CDS xseA NC_007946.1 2770056 2771432 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2770056..2771432 Escherichia coli UTI89 3992175 YP_541819.1 CDS UTI89_C2828 NC_007946.1 2771501 2779552 R RatA-like protein complement(2771501..2779552) Escherichia coli UTI89 3992176 YP_541820.1 CDS sinI NC_007946.1 2779673 2780650 R SinI-like protein complement(2779673..2780650) Escherichia coli UTI89 3992177 YP_541821.1 CDS UTI89_C2830 NC_007946.1 2780705 2782939 R SinH-like protein complement(2780705..2782939) Escherichia coli UTI89 3992178 YP_541822.1 CDS yfgJ NC_007946.1 2783118 2783333 R hypothetical protein complement(2783118..2783333) Escherichia coli UTI89 3992179 YP_541823.2 CDS engA NC_007946.1 2783396 2784868 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2783396..2784868) Escherichia coli UTI89 3992180 YP_541824.1 CDS yfgL NC_007946.1 2784986 2786164 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2784986..2786164) Escherichia coli UTI89 3990171 YP_541825.1 CDS yfgM NC_007946.1 2786175 2786795 R hypothetical protein complement(2786175..2786795) Escherichia coli UTI89 3990172 YP_541826.1 CDS hisS NC_007946.1 2786813 2788087 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2786813..2788087) Escherichia coli UTI89 3990173 YP_541827.1 CDS ispG NC_007946.1 2788198 2789316 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2788198..2789316) Escherichia coli UTI89 3990174 YP_541828.1 CDS yfgA NC_007946.1 2789343 2790350 R cytoskeletal protein RodZ complement(2789343..2790350) Escherichia coli UTI89 3990175 YP_541829.1 CDS yfgB NC_007946.1 2790635 2791789 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2790635..2791789) Escherichia coli UTI89 3990176 YP_541830.1 CDS UTI89_C2839 NC_007946.1 2791915 2792433 D hypothetical protein 2791915..2792433 Escherichia coli UTI89 3990177 YP_541831.1 CDS ndk NC_007946.1 2791939 2792370 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2791939..2792370) Escherichia coli UTI89 3990178 YP_541832.1 CDS pbpC NC_007946.1 2792519 2794831 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2792519..2794831) Escherichia coli UTI89 3990179 YP_541833.1 CDS yfhM NC_007946.1 2794832 2799793 R lipoprotein YfhM complement(2794832..2799793) Escherichia coli UTI89 3990180 YP_541834.2 CDS sseA NC_007946.1 2800000 2800845 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2800000..2800845 Escherichia coli UTI89 3990181 YP_541835.2 CDS sseB NC_007946.1 2801338 2802114 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2801338..2802114) Escherichia coli UTI89 3990182 YP_541836.1 CDS pepB NC_007946.1 2802256 2803539 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase complement(2802256..2803539) Escherichia coli UTI89 3990183 YP_541837.1 CDS yfhJ NC_007946.1 2803598 2803798 R hypothetical protein complement(2803598..2803798) Escherichia coli UTI89 3990184 YP_541838.1 CDS fdx NC_007946.1 2803810 2804145 R (2Fe-2S)-binding protein complement(2803810..2804145) Escherichia coli UTI89 3990185 YP_541839.2 CDS hscA NC_007946.1 2804147 2805997 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2804147..2805997) Escherichia coli UTI89 3990186 YP_541840.1 CDS hscB NC_007946.1 2806014 2806529 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2806014..2806529) Escherichia coli UTI89 3990187 YP_541841.1 CDS iscA NC_007946.1 2806625 2806954 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2806625..2806954) Escherichia coli UTI89 3990188 YP_541842.1 CDS iscU NC_007946.1 2806965 2807351 R synonym: yfhN, nifU, b2529; scaffold protein complement(2806965..2807351) Escherichia coli UTI89 3990189 YP_541843.1 CDS iscS NC_007946.1 2807379 2808617 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2807379..2808617) Escherichia coli UTI89 3990190 YP_541844.1 CDS iscR NC_007946.1 2808705 2809193 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2808705..2809193) Escherichia coli UTI89 3990191 YP_541845.1 CDS yfhQ NC_007946.1 2809463 2810203 R ATP synthase subunit beta complement(2809463..2810203) Escherichia coli UTI89 3990192 YP_541846.1 CDS suhB NC_007946.1 2810322 2811125 D inositol monophosphatase 2810322..2811125 Escherichia coli UTI89 3990193 YP_541847.1 CDS UTI89_C2856 NC_007946.1 2811243 2812124 D hypothetical protein 2811243..2812124 Escherichia coli UTI89 3990194 YP_541848.2 CDS csiE NC_007946.1 2812315 2813595 D stationary phase inducible protein CsiE 2812315..2813595 Escherichia coli UTI89 3990195 YP_541849.1 CDS hcaT NC_007946.1 2813587 2814726 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(2813587..2814726) Escherichia coli UTI89 3990196 YP_541850.1 CDS UTI89_C2859 NC_007946.1 2814760 2814903 R hypothetical protein complement(2814760..2814903) Escherichia coli UTI89 3990197 YP_541851.1 CDS UTI89_C2860 NC_007946.1 2814946 2815098 D hypothetical protein 2814946..2815098 Escherichia coli UTI89 3990198 YP_541852.1 CDS yphA NC_007946.1 2815050 2815517 D hypothetical protein 2815050..2815517 Escherichia coli UTI89 3990199 YP_541853.1 CDS UTI89_C2862 NC_007946.1 2815305 2815613 R hypothetical protein complement(2815305..2815613) Escherichia coli UTI89 3990200 YP_541854.1 CDS yphB NC_007946.1 2815677 2816549 R hypothetical protein complement(2815677..2816549) Escherichia coli UTI89 3990201 YP_541855.1 CDS gutB NC_007946.1 2816561 2817655 R sorbitol dehydrogenase complement(2816561..2817655) Escherichia coli UTI89 3990202 YP_541856.1 CDS yphD NC_007946.1 2817688 2818686 R ABC transporter permease complement(2817688..2818686) Escherichia coli UTI89 3990203 YP_541857.1 CDS yphE NC_007946.1 2818711 2820222 R ABC transporter ATP-binding protein complement(2818711..2820222) Escherichia coli UTI89 3990204 YP_541858.1 CDS yphF NC_007946.1 2820245 2821228 R ABC transporter periplasmic-binding protein complement(2820245..2821228) Escherichia coli UTI89 3990205 YP_541859.1 CDS yphG NC_007946.1 2821325 2824699 R hypothetical protein complement(2821325..2824699) Escherichia coli UTI89 3990206 YP_541860.1 CDS yphH NC_007946.1 2824724 2825917 D hypothetical protein 2824724..2825917 Escherichia coli UTI89 3990207 YP_541861.1 CDS glyA NC_007946.1 2825981 2827240 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2825981..2827240) Escherichia coli UTI89 3990208 YP_541862.1 CDS hmpA NC_007946.1 2827563 2828753 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2827563..2828753 Escherichia coli UTI89 3990209 YP_541863.1 CDS glnB NC_007946.1 2828798 2829136 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2828798..2829136) Escherichia coli UTI89 3989783 YP_541864.1 CDS yfhA NC_007946.1 2829197 2830570 R hypothetical protein complement(2829197..2830570) Escherichia coli UTI89 3989784 YP_541865.1 CDS yfhG NC_007946.1 2830521 2831240 R hypothetical protein complement(2830521..2831240) Escherichia coli UTI89 3989785 YP_541866.1 CDS UTI89_C2875 NC_007946.1 2831177 2831332 D hypothetical protein 2831177..2831332 Escherichia coli UTI89 3989786 YP_541867.1 CDS yfhK NC_007946.1 2831399 2832889 R sensor-like histidine kinase YfhK complement(2831399..2832889) Escherichia coli UTI89 3989787 YP_541868.1 CDS purL NC_007946.1 2833402 2837445 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2833402..2837445) Escherichia coli UTI89 3989788 YP_541869.1 CDS yfhD NC_007946.1 2837548 2839104 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2837548..2839104 Escherichia coli UTI89 3989789 YP_541870.1 CDS yfhC NC_007946.1 2839101 2839637 R tRNA-specific adenosine deaminase complement(2839101..2839637) Escherichia coli UTI89 3989790 YP_541871.1 CDS UTI89_C2880 NC_007946.1 2839662 2840297 R hypothetical protein complement(2839662..2840297) Escherichia coli UTI89 3989791 YP_541872.2 CDS yfhH NC_007946.1 2840506 2841354 D DNA-binding transcriptional regulator 2840506..2841354 Escherichia coli UTI89 3989792 YP_541873.1 CDS yfhL NC_007946.1 2841410 2841670 D ferredoxin-like protein YfhL 2841410..2841670 Escherichia coli UTI89 3989793 YP_541874.1 CDS UTI89_C2883 NC_007946.1 2841941 2842093 R hypothetical protein complement(2841941..2842093) Escherichia coli UTI89 3989794 YP_541875.1 CDS acpS NC_007946.1 2842365 2842745 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2842365..2842745) Escherichia coli UTI89 3989795 YP_541876.1 CDS pdxJ NC_007946.1 2842745 2843491 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2842745..2843491) Escherichia coli UTI89 3989796 YP_541877.1 CDS recO NC_007946.1 2843488 2844216 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2843488..2844216) Escherichia coli UTI89 3989797 YP_541878.1 CDS era NC_007946.1 2844228 2845133 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2844228..2845133) Escherichia coli UTI89 3989798 YP_541879.1 CDS rnc NC_007946.1 2845130 2845810 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2845130..2845810) Escherichia coli UTI89 3989799 YP_541880.1 CDS UTI89_C2889 NC_007946.1 2845868 2846026 D hypothetical protein 2845868..2846026 Escherichia coli UTI89 3989800 YP_541881.1 CDS lepB NC_007946.1 2846077 2847051 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2846077..2847051) Escherichia coli UTI89 3989801 YP_541882.1 CDS lepA NC_007946.1 2847067 2848866 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2847067..2848866) Escherichia coli UTI89 3989802 YP_541883.1 CDS rseC NC_007946.1 2849064 2849543 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2849064..2849543) Escherichia coli UTI89 3992200 YP_541884.1 CDS rseB NC_007946.1 2849540 2850496 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2849540..2850496) Escherichia coli UTI89 3992201 YP_541885.1 CDS rseA NC_007946.1 2850496 2851146 R anti-RNA polymerase sigma factor SigE complement(2850496..2851146) Escherichia coli UTI89 3992202 YP_541886.1 CDS rpoE NC_007946.1 2851179 2851787 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2851179..2851787) Escherichia coli UTI89 3992203 YP_541887.1 CDS nadB NC_007946.1 2852162 2853784 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2852162..2853784 Escherichia coli UTI89 3992204 YP_541888.1 CDS yfiC NC_007946.1 2853769 2854626 R hypothetical protein complement(2853769..2854626) Escherichia coli UTI89 3992205 YP_541889.1 CDS UTI89_C2898 NC_007946.1 2854638 2855972 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2854638..2855972 Escherichia coli UTI89 3992206 YP_541890.1 CDS yfiE NC_007946.1 2856005 2856931 R transcriptional regulator YfiE complement(2856005..2856931) Escherichia coli UTI89 3992207 YP_541891.1 CDS yfiK NC_007946.1 2856989 2857576 D neutral amino-acid efflux protein 2856989..2857576 Escherichia coli UTI89 3992208 YP_541892.2 CDS yfiD NC_007946.1 2857632 2858015 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2857632..2858015) Escherichia coli UTI89 3992209 YP_541893.1 CDS ung NC_007946.1 2858320 2859009 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2858320..2859009 Escherichia coli UTI89 3992210 YP_541894.1 CDS yfiF NC_007946.1 2859057 2860169 R methyltransferase complement(2859057..2860169) Escherichia coli UTI89 3992211 YP_541895.1 CDS UTI89_C2904 NC_007946.1 2860084 2860287 R hypothetical protein complement(2860084..2860287) Escherichia coli UTI89 3992212 YP_541896.1 CDS trxC NC_007946.1 2860301 2860720 D thioredoxin 2860301..2860720 Escherichia coli UTI89 3992213 YP_541897.1 CDS yfiP NC_007946.1 2860738 2861487 D hypothetical protein 2860738..2861487 Escherichia coli UTI89 3992214 YP_541898.1 CDS yfiQ NC_007946.1 2861519 2864179 D hypothetical protein 2861519..2864179 Escherichia coli UTI89 3992215 YP_541899.1 CDS pssA NC_007946.1 2864290 2865648 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2864290..2865648 Escherichia coli UTI89 3992216 YP_541900.1 CDS yfiM NC_007946.1 2865673 2866017 D hypothetical protein 2865673..2866017 Escherichia coli UTI89 3992217 YP_541901.1 CDS kgtP NC_007946.1 2866014 2867405 R alpha-ketoglutarate transporter complement(2866014..2867405) Escherichia coli UTI89 3992218 YP_541902.1 CDS UTI89_C2911 NC_007946.1 2867421 2867681 D hypothetical protein 2867421..2867681 Escherichia coli UTI89 3992219 YP_541903.1 CDS UTI89_C2912 NC_007946.1 2867822 2868346 D hypothetical protein 2867822..2868346 Escherichia coli UTI89 3992220 YP_541904.1 CDS UTI89_C2913 NC_007946.1 2868217 2868621 R IS621-Tnp; transposase complement(2868217..2868621) Escherichia coli UTI89 3992221 YP_541905.1 CDS UTI89_C2914 NC_007946.1 2868472 2868840 D hypothetical protein 2868472..2868840 Escherichia coli UTI89 3992222 YP_541906.1 CDS UTI89_C2915 NC_007946.1 2868865 2869587 R transposase InsK for insertion sequence element IS150 complement(2868865..2869587) Escherichia coli UTI89 3992223 YP_541911.1 CDS UTI89_C2924 NC_007946.1 2875418 2875666 D hypothetical protein 2875418..2875666 Escherichia coli UTI89 3992232 YP_541912.1 CDS clpB NC_007946.1 2875801 2878386 R protein disaggregation chaperone complement(2875801..2878386) Escherichia coli UTI89 3992233 YP_541913.1 CDS yfiH NC_007946.1 2878504 2879235 R hypothetical protein complement(2878504..2879235) Escherichia coli UTI89 3992234 YP_541914.1 CDS rluD NC_007946.1 2879232 2880212 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2879232..2880212) Escherichia coli UTI89 3992332 YP_541915.1 CDS UTI89_C2928 NC_007946.1 2880347 2881084 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2880347..2881084 Escherichia coli UTI89 3992333 YP_541916.1 CDS UTI89_C2929 NC_007946.1 2881113 2881319 D hypothetical protein 2881113..2881319 Escherichia coli UTI89 3992334 YP_541917.1 CDS UTI89_C2930 NC_007946.1 2881273 2881809 R hypothetical protein complement(2881273..2881809) Escherichia coli UTI89 3992335 YP_541918.1 CDS UTI89_C2931 NC_007946.1 2881354 2881695 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2881354..2881695 Escherichia coli UTI89 3992336 YP_541919.1 CDS pheA NC_007946.1 2881945 2883105 D bifunctional P protein; catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2881945..2883105 Escherichia coli UTI89 3992337 YP_541920.1 CDS tyrA NC_007946.1 2883148 2884269 R bifunctional T protein; catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2883148..2884269) Escherichia coli UTI89 3992338 YP_541921.1 CDS aroF NC_007946.1 2884280 2885419 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2884280..2885419) Escherichia coli UTI89 3992339 YP_541922.1 CDS yfiL NC_007946.1 2885542 2885925 D hypothetical protein 2885542..2885925 Escherichia coli UTI89 3992340 YP_541923.1 CDS yfiR NC_007946.1 2886074 2886592 D hypothetical protein 2886074..2886592 Escherichia coli UTI89 3992341 YP_541924.1 CDS yfiN NC_007946.1 2886582 2887808 D hypothetical protein 2886582..2887808 Escherichia coli UTI89 3992342 YP_541925.1 CDS yfiB NC_007946.1 2887824 2888306 D outer membrane lipoprotein 2887824..2888306 Escherichia coli UTI89 3992343 YP_541926.1 CDS rplS NC_007946.1 2888383 2888730 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2888383..2888730) Escherichia coli UTI89 3992344 YP_541927.1 CDS trmD NC_007946.1 2888772 2889539 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(2888772..2889539) Escherichia coli UTI89 3992345 YP_541928.1 CDS rimM NC_007946.1 2889570 2890127 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2889570..2890127) Escherichia coli UTI89 3992346 YP_541929.2 CDS rpsP NC_007946.1 2890137 2890385 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2890137..2890385) Escherichia coli UTI89 3992347 YP_541930.1 CDS ffh NC_007946.1 2890522 2891883 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2890522..2891883) Escherichia coli UTI89 3992348 YP_541931.1 CDS ypjD NC_007946.1 2891975 2892841 D hypothetical protein 2891975..2892841 Escherichia coli UTI89 3992349 YP_541932.2 CDS yfjD NC_007946.1 2892952 2894148 D hypothetical protein 2892952..2894148 Escherichia coli UTI89 3992350 YP_541933.1 CDS UTI89_C2946 NC_007946.1 2894170 2894922 D hypothetical protein 2894170..2894922 Escherichia coli UTI89 3992351 YP_541934.1 CDS grpE NC_007946.1 2894203 2894796 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2894203..2894796) Escherichia coli UTI89 3992970 YP_541935.1 CDS yfjC NC_007946.1 2894793 2895044 R hypothetical protein complement(2894793..2895044) Escherichia coli UTI89 3992971 YP_541936.1 CDS ppnK NC_007946.1 2894919 2895797 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2894919..2895797 Escherichia coli UTI89 3992972 YP_541937.1 CDS recN NC_007946.1 2895883 2897544 D recombination and repair protein 2895883..2897544 Escherichia coli UTI89 3992973 YP_541938.1 CDS smpA NC_007946.1 2897693 2898034 D hypothetical protein 2897693..2898034 Escherichia coli UTI89 3992974 YP_541939.1 CDS yfjF NC_007946.1 2898096 2898404 R hypothetical protein complement(2898096..2898404) Escherichia coli UTI89 3992975 YP_541940.1 CDS yfjG NC_007946.1 2898376 2898852 R hypothetical protein complement(2898376..2898852) Escherichia coli UTI89 3992976 YP_541941.1 CDS smpB NC_007946.1 2898984 2899466 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2898984..2899466 Escherichia coli UTI89 3992977 YP_541942.1 CDS UTI89_C2955 NC_007946.1 2900045 2900299 R hypothetical protein complement(2900045..2900299) Escherichia coli UTI89 3992978 YP_541943.1 CDS UTI89_C2956 NC_007946.1 2900429 2900626 D hypothetical protein 2900429..2900626 Escherichia coli UTI89 3992979 YP_541944.1 CDS UTI89_C2957 NC_007946.1 2900623 2901411 D hypothetical protein 2900623..2901411 Escherichia coli UTI89 3992980 YP_541945.1 CDS UTI89_C2958 NC_007946.1 2901499 2901792 R hypothetical protein complement(2901499..2901792) Escherichia coli UTI89 3992981 YP_541946.1 CDS UTI89_C2959 NC_007946.1 2902003 2902776 R prophage CP-933H hypothetical protein complement(2902003..2902776) Escherichia coli UTI89 3992982 YP_541947.1 CDS UTI89_C2960 NC_007946.1 2903828 2905717 D hypothetical protein 2903828..2905717 Escherichia coli UTI89 3992983 YP_541948.1 CDS yfdK NC_007946.1 2906465 2906908 D hypothetical protein 2906465..2906908 Escherichia coli UTI89 3992984 YP_541949.1 CDS tfaE NC_007946.1 2906880 2907482 R lambdoid prophage e14 tail fiber assembly protein-like protein complement(2906880..2907482) Escherichia coli UTI89 3992985 YP_541950.1 CDS ycfK NC_007946.1 2907482 2908225 R hypothetical protein complement(2907482..2908225) Escherichia coli UTI89 3992986 YP_541951.1 CDS UTI89_C2964 NC_007946.1 2908229 2908813 R bacteriophage V tail protein complement(2908229..2908813) Escherichia coli UTI89 3992987 YP_541952.1 CDS UTI89_C2965 NC_007946.1 2908804 2909862 R bacteriophage V tail protein complement(2908804..2909862) Escherichia coli UTI89 3992524 YP_541953.1 CDS UTI89_C2966 NC_007946.1 2909849 2910274 R bacteriophage V tail protein complement(2909849..2910274) Escherichia coli UTI89 3992525 YP_541954.1 CDS UTI89_C2967 NC_007946.1 2910274 2910822 R bacteriophage V tail protein complement(2910274..2910822) Escherichia coli UTI89 3992526 YP_541955.1 CDS UTI89_C2968 NC_007946.1 2910822 2911901 R bacteriophage V tail protein complement(2910822..2911901) Escherichia coli UTI89 3992527 YP_541956.1 CDS UTI89_C2969 NC_007946.1 2911898 2913253 R bacteriophage V tail/DNA circulation protein complement(2911898..2913253) Escherichia coli UTI89 3992528 YP_541957.1 CDS UTI89_C2970 NC_007946.1 2913287 2915122 R bacteriophage V tail protein complement(2913287..2915122) Escherichia coli UTI89 3992529 YP_541958.1 CDS UTI89_C2971 NC_007946.1 2915264 2915533 R hypothetical protein complement(2915264..2915533) Escherichia coli UTI89 3992530 YP_541959.1 CDS UTI89_C2972 NC_007946.1 2915533 2915889 R hypothetical protein complement(2915533..2915889) Escherichia coli UTI89 3992531 YP_541960.1 CDS UTI89_C2973 NC_007946.1 2915889 2917385 R bacteriophage V tail sheath protein complement(2915889..2917385) Escherichia coli UTI89 3992532 YP_541961.1 CDS UTI89_C2974 NC_007946.1 2917369 2917539 R hypothetical protein complement(2917369..2917539) Escherichia coli UTI89 3992533 YP_541962.1 CDS UTI89_C2975 NC_007946.1 2917548 2918108 R hypothetical protein complement(2917548..2918108) Escherichia coli UTI89 3992534 YP_541963.1 CDS UTI89_C2976 NC_007946.1 2918105 2918611 R hypothetical protein complement(2918105..2918611) Escherichia coli UTI89 3992535 YP_541964.1 CDS UTI89_C2977 NC_007946.1 2918586 2918996 R hypothetical protein complement(2918586..2918996) Escherichia coli UTI89 3992536 YP_541965.1 CDS UTI89_C2978 NC_007946.1 2918622 2919089 D hypothetical protein 2918622..2919089 Escherichia coli UTI89 3992537 YP_541966.1 CDS UTI89_C2979 NC_007946.1 2918993 2919316 R hypothetical protein complement(2918993..2919316) Escherichia coli UTI89 3992538 YP_541967.1 CDS UTI89_C2980 NC_007946.1 2919319 2919519 R hypothetical protein complement(2919319..2919519) Escherichia coli UTI89 3992539 YP_541968.1 CDS UTI89_C2981 NC_007946.1 2919569 2920774 R major capsid protein complement(2919569..2920774) Escherichia coli UTI89 3992540 YP_541969.1 CDS UTI89_C2982 NC_007946.1 2920789 2921475 R pro-head protease complement(2920789..2921475) Escherichia coli UTI89 3992541 YP_541970.1 CDS UTI89_C2983 NC_007946.1 2921417 2922658 R portal protein complement(2921417..2922658) Escherichia coli UTI89 3992542 YP_541971.1 CDS ymfR NC_007946.1 2922658 2922840 R hypothetical protein complement(2922658..2922840) Escherichia coli UTI89 3992543 YP_541972.1 CDS UTI89_C2985 NC_007946.1 2922852 2924585 R bacteriophage V large terminase subunit complement(2922852..2924585) Escherichia coli UTI89 3993044 YP_541973.1 CDS UTI89_C2986 NC_007946.1 2924582 2925076 R bacteriophage V small terminase subunit complement(2924582..2925076) Escherichia coli UTI89 3993045 YP_541974.1 CDS UTI89_C2987 NC_007946.1 2925202 2925552 R hypothetical protein complement(2925202..2925552) Escherichia coli UTI89 3993046 YP_541975.1 CDS UTI89_C2988 NC_007946.1 2926201 2926449 R hypothetical protein complement(2926201..2926449) Escherichia coli UTI89 3993047 YP_541976.1 CDS UTI89_C2989 NC_007946.1 2926523 2926960 R hypothetical protein complement(2926523..2926960) Escherichia coli UTI89 3993048 YP_541977.1 CDS UTI89_C2990 NC_007946.1 2926957 2927433 R endolysin of prophage CP-933X complement(2926957..2927433) Escherichia coli UTI89 3993049 YP_541978.1 CDS UTI89_C2991 NC_007946.1 2927420 2927725 R holin protein of prophage CP-933X complement(2927420..2927725) Escherichia coli UTI89 3993050 YP_541979.1 CDS UTI89_C2992 NC_007946.1 2927877 2928212 R hypothetical protein complement(2927877..2928212) Escherichia coli UTI89 3993051 YP_541980.1 CDS UTI89_C2993 NC_007946.1 2928398 2929180 R lambdoid prophage Qin antitermination protein Q-like protein complement(2928398..2929180) Escherichia coli UTI89 3993052 YP_541981.1 CDS ydfU1 NC_007946.1 2929164 2930159 R hypothetical protein complement(2929164..2930159) Escherichia coli UTI89 3993053 YP_541982.1 CDS UTI89_C2995 NC_007946.1 2930161 2930958 R hypothetical protein complement(2930161..2930958) Escherichia coli UTI89 3993054 YP_541983.1 CDS UTI89_C2996 NC_007946.1 2930978 2931367 R bacteriophage V crossover junction endodeoxyribonuclease complement(2930978..2931367) Escherichia coli UTI89 3993055 YP_541984.1 CDS UTI89_C2997 NC_007946.1 2931364 2931690 R hypothetical protein complement(2931364..2931690) Escherichia coli UTI89 3993056 YP_541985.1 CDS UTI89_C2998 NC_007946.1 2931687 2932340 R bacteriophage V DNA adenine methylase complement(2931687..2932340) Escherichia coli UTI89 3993057 YP_541986.1 CDS yfdN1 NC_007946.1 2932340 2932834 R hypothetical protein complement(2932340..2932834) Escherichia coli UTI89 3993058 YP_541987.1 CDS UTI89_C3000 NC_007946.1 2932831 2933772 R hypothetical protein complement(2932831..2933772) Escherichia coli UTI89 3993059 YP_541988.1 CDS ymfM NC_007946.1 2933782 2934120 R hypothetical protein complement(2933782..2934120) Escherichia coli UTI89 3993060 YP_541989.1 CDS ymfL NC_007946.1 2934117 2934680 R hypothetical protein complement(2934117..2934680) Escherichia coli UTI89 3993061 YP_541990.1 CDS UTI89_C3003 NC_007946.1 2934712 2935215 R hypothetical protein complement(2934712..2935215) Escherichia coli UTI89 3993062 YP_541991.1 CDS ymfK NC_007946.1 2935003 2935677 D phage repressor 2935003..2935677 Escherichia coli UTI89 3992834 YP_541992.1 CDS UTI89_C3005 NC_007946.1 2935880 2936392 R hypothetical protein complement(2935880..2936392) Escherichia coli UTI89 3992835 YP_541993.1 CDS yfdQ1 NC_007946.1 2937289 2938113 D hypothetical protein 2937289..2938113 Escherichia coli UTI89 3992836 YP_541994.1 CDS yfdR1 NC_007946.1 2938214 2938765 D hypothetical protein 2938214..2938765 Escherichia coli UTI89 3992837 YP_541995.1 CDS UTI89_C3008 NC_007946.1 2938850 2939740 D hypothetical protein 2938850..2939740 Escherichia coli UTI89 3992838 YP_541996.1 CDS UTI89_C3009 NC_007946.1 2939949 2941121 D hypothetical protein 2939949..2941121 Escherichia coli UTI89 3992839 YP_541997.1 CDS UTI89_C3010 NC_007946.1 2941113 2941712 R hypothetical protein complement(2941113..2941712) Escherichia coli UTI89 3992840 YP_541998.1 CDS UTI89_C3011 NC_007946.1 2941741 2942067 R hypothetical protein complement(2941741..2942067) Escherichia coli UTI89 3992841 YP_541999.1 CDS UTI89_C3012 NC_007946.1 2942072 2942983 R hypothetical protein complement(2942072..2942983) Escherichia coli UTI89 3992842 YP_542000.1 CDS UTI89_C3013 NC_007946.1 2942958 2943212 D hypothetical protein 2942958..2943212 Escherichia coli UTI89 3992843 YP_542001.1 CDS ygaT NC_007946.1 2943844 2944821 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2943844..2944821 Escherichia coli UTI89 3992844 YP_542002.1 CDS ygaF NC_007946.1 2944775 2946109 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2944775..2946109 Escherichia coli UTI89 3992845 YP_542003.1 CDS gabD NC_007946.1 2946132 2947580 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2946132..2947580 Escherichia coli UTI89 3992846 YP_542004.1 CDS gabT NC_007946.1 2947588 2948874 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2947588..2948874 Escherichia coli UTI89 3992847 YP_542005.2 CDS gabP NC_007946.1 2949112 2950512 D gamma-aminobutyrate transporter 2949112..2950512 Escherichia coli UTI89 3992848 YP_542006.2 CDS ygaE NC_007946.1 2950533 2951195 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2950533..2951195 Escherichia coli UTI89 3992849 YP_542007.1 CDS ygaU NC_007946.1 2951196 2951645 R LysM domain/BON superfamily protein complement(2951196..2951645) Escherichia coli UTI89 3992850 YP_542008.1 CDS UTI89_C3021 NC_007946.1 2951717 2951902 D hypothetical protein 2951717..2951902 Escherichia coli UTI89 3992851 YP_542009.1 CDS yqaE NC_007946.1 2951729 2951887 R hypothetical protein complement(2951729..2951887) Escherichia coli UTI89 3992852 YP_542010.1 CDS ygaV NC_007946.1 2952070 2952369 D transcriptional regulator 2952070..2952369 Escherichia coli UTI89 3992853 YP_542011.1 CDS ygaP NC_007946.1 2952379 2952903 D hypothetical protein 2952379..2952903 Escherichia coli UTI89 3993007 YP_542012.1 CDS stpA NC_007946.1 2952950 2953354 R DNA binding protein, nucleoid-associated complement(2952950..2953354) Escherichia coli UTI89 3993008 YP_542013.1 CDS UTI89_C3026 NC_007946.1 2953768 2953896 D hypothetical protein 2953768..2953896 Escherichia coli UTI89 3993009 YP_542014.1 CDS ygaW NC_007946.1 2954022 2954471 D hypothetical protein 2954022..2954471 Escherichia coli UTI89 3993010 YP_542015.1 CDS ygaC NC_007946.1 2954508 2954852 R hypothetical protein complement(2954508..2954852) Escherichia coli UTI89 3993011 YP_542016.1 CDS ygaM NC_007946.1 2954992 2955333 D hypothetical protein 2954992..2955333 Escherichia coli UTI89 3993012 YP_542017.1 CDS UTI89_C3030 NC_007946.1 2955390 2956724 R hypothetical protein complement(2955390..2956724) Escherichia coli UTI89 3993013 YP_542018.1 CDS UTI89_C3031 NC_007946.1 2956812 2957243 D hypothetical protein 2956812..2957243 Escherichia coli UTI89 3993014 YP_542019.1 CDS UTI89_C3032 NC_007946.1 2957428 2957682 R hypothetical protein complement(2957428..2957682) Escherichia coli UTI89 3993015 YP_542020.1 CDS nrdH NC_007946.1 2957452 2957697 D glutaredoxin-like protein 2957452..2957697 Escherichia coli UTI89 3993016 YP_542021.1 CDS nrdI NC_007946.1 2957694 2958104 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2957694..2958104 Escherichia coli UTI89 3993017 YP_542022.1 CDS nrdE NC_007946.1 2958077 2960221 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2958077..2960221 Escherichia coli UTI89 3993018 YP_542023.1 CDS nrdF NC_007946.1 2960231 2961190 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2960231..2961190 Escherichia coli UTI89 3993019 YP_542024.1 CDS proV NC_007946.1 2961546 2962748 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2961546..2962748 Escherichia coli UTI89 3993020 YP_542025.1 CDS proW NC_007946.1 2962741 2963805 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2962741..2963805 Escherichia coli UTI89 3993021 YP_542026.2 CDS proX NC_007946.1 2963863 2964855 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2963863..2964855 Escherichia coli UTI89 3993022 YP_542027.1 CDS UTI89_C3040 NC_007946.1 2964908 2965054 D hypothetical protein 2964908..2965054 Escherichia coli UTI89 3993023 YP_542028.1 CDS ygaY NC_007946.1 2965047 2966231 D transport protein 2965047..2966231 Escherichia coli UTI89 3993024 YP_542029.1 CDS ygaZ NC_007946.1 2966355 2967092 D hypothetical protein 2966355..2967092 Escherichia coli UTI89 3993025 YP_542030.1 CDS ygaH NC_007946.1 2967082 2967417 D hypothetical protein 2967082..2967417 Escherichia coli UTI89 3990578 YP_542031.1 CDS mprA NC_007946.1 2967508 2968038 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2967508..2968038 Escherichia coli UTI89 3990579 YP_542032.1 CDS emrA NC_007946.1 2968153 2969337 D multidrug resistance protein A 2968153..2969337 Escherichia coli UTI89 3990580 YP_542033.1 CDS emrB NC_007946.1 2969345 2970892 D multidrug resistance protein B 2969345..2970892 Escherichia coli UTI89 3990581 YP_542034.1 CDS UTI89_C3047 NC_007946.1 2971150 2971857 D hypothetical protein 2971150..2971857 Escherichia coli UTI89 3990582 YP_542035.1 CDS UTI89_C3048 NC_007946.1 2971854 2972966 D hypothetical protein 2971854..2972966 Escherichia coli UTI89 3990583 YP_542036.1 CDS luxS NC_007946.1 2973017 2973532 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(2973017..2973532) Escherichia coli UTI89 3990584 YP_542037.1 CDS gshA NC_007946.1 2973683 2975239 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(2973683..2975239) Escherichia coli UTI89 3990585 YP_542038.1 CDS yqaA NC_007946.1 2975312 2975740 R hypothetical protein complement(2975312..2975740) Escherichia coli UTI89 3990586 YP_542039.1 CDS yqaB NC_007946.1 2975737 2976303 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(2975737..2976303) Escherichia coli UTI89 3990587 YP_542040.1 CDS csrA NC_007946.1 2977353 2977538 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(2977353..2977538) Escherichia coli UTI89 3990592 YP_542041.1 CDS alaS NC_007946.1 2977773 2980403 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2977773..2980403) Escherichia coli UTI89 3990210 YP_542042.1 CDS UTI89_C3059 NC_007946.1 2980308 2980490 D hypothetical protein 2980308..2980490 Escherichia coli UTI89 3990211 YP_542043.1 CDS recX NC_007946.1 2980531 2981031 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(2980531..2981031) Escherichia coli UTI89 3990212 YP_542044.1 CDS recA NC_007946.1 2981100 2982161 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2981100..2982161) Escherichia coli UTI89 3990213 YP_542045.1 CDS ygaD NC_007946.1 2982241 2982741 R competence damage-inducible protein A complement(2982241..2982741) Escherichia coli UTI89 3990214 YP_542046.1 CDS mltB NC_007946.1 2982883 2984073 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(2982883..2984073) Escherichia coli UTI89 3990215 YP_542047.1 CDS srlA NC_007946.1 2984225 2984788 D PTS system glucitol/sorbitol-specific transporter subunit IIC2 2984225..2984788 Escherichia coli UTI89 3990216 YP_542048.1 CDS srlE NC_007946.1 2984785 2985744 D PTS system glucitol-sorbitol-specific transporter subunit IIBC 2984785..2985744 Escherichia coli UTI89 3990217 YP_542049.1 CDS srlB NC_007946.1 2985755 2986126 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2985755..2986126 Escherichia coli UTI89 3990218 YP_542050.1 CDS srlD NC_007946.1 2986130 2986909 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2986130..2986909 Escherichia coli UTI89 3990219 YP_542051.1 CDS gutM NC_007946.1 2987015 2987374 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2987015..2987374 Escherichia coli UTI89 3990220 YP_542052.1 CDS srlR NC_007946.1 2987441 2988214 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2987441..2988214 Escherichia coli UTI89 3990221 YP_542053.1 CDS gutQ NC_007946.1 2988207 2989172 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2988207..2989172 Escherichia coli UTI89 3990222 YP_542054.1 CDS ygaA NC_007946.1 2989169 2990683 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator complement(2989169..2990683) Escherichia coli UTI89 3990223 YP_542055.1 CDS norV NC_007946.1 2990870 2992309 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2990870..2992309 Escherichia coli UTI89 3990224 YP_542056.1 CDS ygbD NC_007946.1 2992306 2993439 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2992306..2993439 Escherichia coli UTI89 3990225 YP_542057.1 CDS hypF NC_007946.1 2993663 2995987 R hydrogenase maturation protein HypF complement(2993663..2995987) Escherichia coli UTI89 3990226 YP_542058.1 CDS hydN NC_007946.1 2996068 2996610 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(2996068..2996610) Escherichia coli UTI89 3990227 YP_542059.1 CDS ascG NC_007946.1 2996744 2997796 R ascBF operon repressor complement(2996744..2997796) Escherichia coli UTI89 3990228 YP_542060.1 CDS ascF NC_007946.1 2998014 2999471 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC 2998014..2999471 Escherichia coli UTI89 3990229 YP_542061.1 CDS ascB NC_007946.1 2999480 3000904 D cryptic 6-phospho-beta-glucosidase 2999480..3000904 Escherichia coli UTI89 3989998 YP_542062.1 CDS ygjM NC_007946.1 3001002 3001421 R hypothetical protein complement(3001002..3001421) Escherichia coli UTI89 3989999 YP_542063.1 CDS hycI NC_007946.1 3001666 3002136 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3001666..3002136) Escherichia coli UTI89 3990000 YP_542064.1 CDS hycH NC_007946.1 3002129 3002539 R formate hydrogenlyase maturation protein HycH complement(3002129..3002539) Escherichia coli UTI89 3990001 YP_542065.1 CDS hycG NC_007946.1 3002536 3003303 R formate hydrogenlyase subunit 7 complement(3002536..3003303) Escherichia coli UTI89 3990002 YP_542066.1 CDS hycF NC_007946.1 3003303 3003845 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3003303..3003845) Escherichia coli UTI89 3990003 YP_542067.1 CDS hycE NC_007946.1 3003855 3005564 R formate hydrogenlyase subunit 5 complement(3003855..3005564) Escherichia coli UTI89 3990004 YP_542068.1 CDS hycD NC_007946.1 3005582 3006505 R membrane-spanning protein of formate hydrogenase complement(3005582..3006505) Escherichia coli UTI89 3990005 YP_542069.1 CDS hycC NC_007946.1 3006508 3008334 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3006508..3008334) Escherichia coli UTI89 3990006 YP_542070.1 CDS hycB NC_007946.1 3008331 3008942 R formate hydrogenlyase subunit 2 complement(3008331..3008942) Escherichia coli UTI89 3990007 YP_542071.1 CDS hycA NC_007946.1 3009067 3009528 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3009067..3009528) Escherichia coli UTI89 3990008 YP_542072.1 CDS hypA NC_007946.1 3009728 3010090 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3009728..3010090 Escherichia coli UTI89 3990009 YP_542073.1 CDS hypB NC_007946.1 3010094 3010966 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3010094..3010966 Escherichia coli UTI89 3990010 YP_542074.1 CDS hypC NC_007946.1 3010957 3011229 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3010957..3011229 Escherichia coli UTI89 3990011 YP_542075.1 CDS hypD NC_007946.1 3011229 3012350 D hydrogenase isoenzymes formation protein HypD 3011229..3012350 Escherichia coli UTI89 3990012 YP_542076.1 CDS hypE NC_007946.1 3012347 3013357 D hydrogenase isoenzymes formation protein HypE 3012347..3013357 Escherichia coli UTI89 3990013 YP_542077.1 CDS fhlA NC_007946.1 3013395 3015509 D formate hydrogenlyase transcriptional activator 3013395..3015509 Escherichia coli UTI89 3990014 YP_542078.1 CDS UTI89_C3095 NC_007946.1 3015515 3015982 D potential molybdenum-pterin-binding-protein 3015515..3015982 Escherichia coli UTI89 3990015 YP_542079.1 CDS ygbA NC_007946.1 3016021 3016365 R hypothetical protein complement(3016021..3016365) Escherichia coli UTI89 3990016 YP_542080.1 CDS UTI89_C3097 NC_007946.1 3016420 3016575 R hypothetical protein complement(3016420..3016575) Escherichia coli UTI89 3994194 YP_542081.1 CDS mutS NC_007946.1 3016651 3019212 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3016651..3019212 Escherichia coli UTI89 3994195 YP_542082.1 CDS insBcp5 NC_007946.1 3019477 3019980 R InsBcp5 protein complement(3019477..3019980) Escherichia coli UTI89 3994196 YP_542083.1 CDS UTI89_C3100 NC_007946.1 3019991 3020203 R hypothetical protein complement(3019991..3020203) Escherichia coli UTI89 3994197 YP_542084.1 CDS ygbI NC_007946.1 3020604 3021401 R transcriptional regulator YgbI complement(3020604..3021401) Escherichia coli UTI89 3994198 YP_542085.1 CDS ygbJ NC_007946.1 3021567 3022475 D oxidoreductase YgbJ 3021567..3022475 Escherichia coli UTI89 3994199 YP_542086.1 CDS ygbK NC_007946.1 3022472 3023734 D hypothetical protein 3022472..3023734 Escherichia coli UTI89 3994200 YP_542087.1 CDS ygbL NC_007946.1 3023731 3024369 D aldolase 3023731..3024369 Escherichia coli UTI89 3994201 YP_542088.1 CDS ygbM NC_007946.1 3024374 3025150 D hypothetical protein 3024374..3025150 Escherichia coli UTI89 3994202 YP_542089.1 CDS ygbN NC_007946.1 3025239 3026603 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3025239..3026603 Escherichia coli UTI89 3994203 YP_542090.1 CDS UTI89_C3107 NC_007946.1 3026746 3027789 R hypothetical protein complement(3026746..3027789) Escherichia coli UTI89 3994204 YP_542091.1 CDS UTI89_C3108 NC_007946.1 3027808 3027954 D hypothetical protein 3027808..3027954 Escherichia coli UTI89 3994205 YP_542092.1 CDS UTI89_C3109 NC_007946.1 3028014 3028565 D hypothetical protein 3028014..3028565 Escherichia coli UTI89 3994206 YP_542093.1 CDS UTI89_C3110 NC_007946.1 3028683 3029309 D hypothetical protein 3028683..3029309 Escherichia coli UTI89 3994207 YP_542094.1 CDS rpoS NC_007946.1 3028743 3029771 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(3028743..3029771) Escherichia coli UTI89 3994208 YP_542095.1 CDS nlpD NC_007946.1 3029798 3030937 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3029798..3030937) Escherichia coli UTI89 3994209 YP_542096.1 CDS UTI89_C3113 NC_007946.1 3030795 3030962 D hypothetical protein 3030795..3030962 Escherichia coli UTI89 3994210 YP_542097.1 CDS pcm NC_007946.1 3031077 3031703 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3031077..3031703) Escherichia coli UTI89 3994211 YP_542098.1 CDS surE NC_007946.1 3031697 3032503 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3031697..3032503) Escherichia coli UTI89 3994212 YP_542099.1 CDS truD NC_007946.1 3032439 3033488 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3032439..3033488) Escherichia coli UTI89 3994213 YP_542100.1 CDS ispF NC_007946.1 3033485 3033964 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3033485..3033964) Escherichia coli UTI89 3990442 YP_542101.1 CDS ispD NC_007946.1 3033964 3034674 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3033964..3034674) Escherichia coli UTI89 3990443 YP_542102.1 CDS ftsB NC_007946.1 3034693 3035004 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3034693..3035004) Escherichia coli UTI89 3990444 YP_542103.1 CDS ygbE NC_007946.1 3035197 3035520 R hypothetical protein complement(3035197..3035520) Escherichia coli UTI89 3990445 YP_542104.1 CDS cysC NC_007946.1 3035570 3036175 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3035570..3036175) Escherichia coli UTI89 3990446 YP_542105.1 CDS cysN NC_007946.1 3036175 3037602 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3036175..3037602) Escherichia coli UTI89 3990447 YP_542106.1 CDS cysD NC_007946.1 3037604 3038512 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3037604..3038512) Escherichia coli UTI89 3990448 YP_542107.1 CDS iap NC_007946.1 3038764 3039801 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3038764..3039801 Escherichia coli UTI89 3990449 YP_542108.1 CDS UTI89_C3125 NC_007946.1 3039926 3040078 R hypothetical protein complement(3039926..3040078) Escherichia coli UTI89 3990450 YP_542109.1 CDS cysH NC_007946.1 3040343 3041077 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3040343..3041077) Escherichia coli UTI89 3990451 YP_542110.1 CDS cysI NC_007946.1 3041151 3042863 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3041151..3042863) Escherichia coli UTI89 3990452 YP_542111.1 CDS cysJ NC_007946.1 3042863 3044662 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3042863..3044662) Escherichia coli UTI89 3990453 YP_542112.1 CDS ygcM NC_007946.1 3044894 3045343 D 6-pyruvoyl tetrahydrobiopterin synthase 3044894..3045343 Escherichia coli UTI89 3990454 YP_542113.1 CDS ygcN NC_007946.1 3045391 3046692 D electron transfer flavoprotein-quinone oxidoreductase ygcN 3045391..3046692 Escherichia coli UTI89 3990455 YP_542114.1 CDS ygcO NC_007946.1 3046647 3046943 D ferredoxin-like protein YgcO 3046647..3046943 Escherichia coli UTI89 3990456 YP_542115.1 CDS ygcP NC_007946.1 3046960 3047535 D anti-terminator regulatory protein 3046960..3047535 Escherichia coli UTI89 3990457 YP_542116.1 CDS ygcQ NC_007946.1 3047683 3048576 R flavoprotein complement(3047683..3048576) Escherichia coli UTI89 3990458 YP_542117.1 CDS ygcR NC_007946.1 3048540 3049325 R transport protein complement(3048540..3049325) Escherichia coli UTI89 3990459 YP_542118.1 CDS ygcS NC_007946.1 3049297 3050706 R metabolite transport protein YgcS complement(3049297..3050706) Escherichia coli UTI89 3990460 YP_542119.1 CDS UTI89_C3136 NC_007946.1 3050728 3052182 R hypothetical protein complement(3050728..3052182) Escherichia coli UTI89 3993679 YP_542120.1 CDS ygcW NC_007946.1 3052252 3053112 R oxidoreductase YgcW complement(3052252..3053112) Escherichia coli UTI89 3993680 YP_542121.1 CDS yqcE NC_007946.1 3053356 3054633 D hypothetical protein 3053356..3054633 Escherichia coli UTI89 3993681 YP_542122.1 CDS ygcE NC_007946.1 3054660 3056138 D sugar kinase YgcE 3054660..3056138 Escherichia coli UTI89 3993682 YP_542123.1 CDS ygcF NC_007946.1 3056612 3057283 R hypothetical protein complement(3056612..3057283) Escherichia coli UTI89 3993683 YP_542124.1 CDS UTI89_C3141 NC_007946.1 3057317 3057442 D hypothetical protein 3057317..3057442 Escherichia coli UTI89 3993684 YP_542125.1 CDS UTI89_C3142 NC_007946.1 3057456 3058070 D hypothetical protein 3057456..3058070 Escherichia coli UTI89 3993685 YP_542126.1 CDS UTI89_C3143 NC_007946.1 3058054 3058977 D hypothetical protein 3058054..3058977 Escherichia coli UTI89 3993686 YP_542127.1 CDS UTI89_C3144 NC_007946.1 3058581 3058871 R hypothetical protein complement(3058581..3058871) Escherichia coli UTI89 3993687 YP_542128.1 CDS UTI89_C3145 NC_007946.1 3058992 3060140 D hypothetical protein 3058992..3060140 Escherichia coli UTI89 3993688 YP_542130.1 CDS UTI89_C3147 NC_007946.1 3060134 3061039 D hypothetical protein 3060134..3061039 Escherichia coli UTI89 3993690 YP_542131.1 CDS eno NC_007946.1 3061099 3062397 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3061099..3062397) Escherichia coli UTI89 3993691 YP_542132.1 CDS pyrG NC_007946.1 3062485 3064122 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3062485..3064122) Escherichia coli UTI89 3993692 YP_542133.1 CDS mazG NC_007946.1 3064350 3065141 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase complement(3064350..3065141) Escherichia coli UTI89 3993693 YP_542134.1 CDS chpA NC_007946.1 3065213 3065548 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3065213..3065548) Escherichia coli UTI89 3993694 YP_542135.1 CDS UTI89_C3152 NC_007946.1 3065465 3065827 D hypothetical protein 3065465..3065827 Escherichia coli UTI89 3993695 YP_542136.1 CDS chpR NC_007946.1 3065548 3065796 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(3065548..3065796) Escherichia coli UTI89 3993696 YP_542137.1 CDS relA NC_007946.1 3065874 3068108 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3065874..3068108) Escherichia coli UTI89 3993697 YP_542138.1 CDS rumA NC_007946.1 3068156 3069457 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3068156..3069457) Escherichia coli UTI89 3993698 YP_542139.1 CDS barA NC_007946.1 3069514 3072270 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3069514..3072270 Escherichia coli UTI89 3990291 YP_542140.1 CDS gudD NC_007946.1 3072501 3073841 R synonym: gdh1, b2787, ygcX, EG13167; glucarate dehydratase complement(3072501..3073841) Escherichia coli UTI89 3990292 YP_542141.1 CDS ygcY NC_007946.1 3073862 3075202 R glucarate dehydratase related protein complement(3073862..3075202) Escherichia coli UTI89 3990293 YP_542142.1 CDS UTI89_C3159 NC_007946.1 3075204 3076556 R glucarate transporter complement(3075204..3076556) Escherichia coli UTI89 3990294 YP_542143.1 CDS yqcA NC_007946.1 3076990 3077439 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3076990..3077439) Escherichia coli UTI89 3990295 YP_542144.1 CDS truC NC_007946.1 3077457 3078239 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3077457..3078239) Escherichia coli UTI89 3990296 YP_542145.1 CDS yqcC NC_007946.1 3078239 3078568 R hypothetical protein complement(3078239..3078568) Escherichia coli UTI89 3990297 YP_542146.1 CDS syd NC_007946.1 3079190 3079735 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3079190..3079735) Escherichia coli UTI89 3990298 YP_542147.1 CDS queF NC_007946.1 3079803 3080651 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3079803..3080651 Escherichia coli UTI89 3990299 YP_542148.1 CDS ygdH NC_007946.1 3080763 3082127 D hypothetical protein 3080763..3082127 Escherichia coli UTI89 3990300 YP_542149.1 CDS UTI89_C3166 NC_007946.1 3082657 3084084 R hypothetical protein complement(3082657..3084084) Escherichia coli UTI89 3990301 YP_542150.1 CDS sdaC NC_007946.1 3082684 3083973 D serine transporter 3082684..3083973 Escherichia coli UTI89 3990302 YP_542151.1 CDS sdaB NC_007946.1 3084031 3085398 D L-serine dehydratase (deaminase), L-SD2 3084031..3085398 Escherichia coli UTI89 3990303 YP_542152.1 CDS xni NC_007946.1 3085420 3086265 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3085420..3086265 Escherichia coli UTI89 3990304 YP_542153.1 CDS fucO NC_007946.1 3086370 3087521 R L-1,2-propanediol oxidoreductase complement(3086370..3087521) Escherichia coli UTI89 3990305 YP_542154.1 CDS fucA NC_007946.1 3087546 3088193 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3087546..3088193) Escherichia coli UTI89 3990306 YP_542155.1 CDS UTI89_C3172 NC_007946.1 3088383 3088520 D hypothetical protein 3088383..3088520 Escherichia coli UTI89 3990307 YP_542156.1 CDS fucP NC_007946.1 3088740 3090056 D L-fucose transporter 3088740..3090056 Escherichia coli UTI89 3990308 YP_542157.1 CDS fucI NC_007946.1 3090089 3091864 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3090089..3091864 Escherichia coli UTI89 3990309 YP_542158.1 CDS fucK NC_007946.1 3091943 3093391 D L-fuculokinase 3091943..3093391 Escherichia coli UTI89 3990275 YP_542159.1 CDS fucU NC_007946.1 3093393 3093815 D protein of fucose operon 3093393..3093815 Escherichia coli UTI89 3990276 YP_542160.1 CDS fucR NC_007946.1 3093864 3094604 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3093864..3094604 Escherichia coli UTI89 3990277 YP_542161.1 CDS ygdE NC_007946.1 3094648 3095748 R RNA 2'-O-ribose methyltransferase complement(3094648..3095748) Escherichia coli UTI89 3990278 YP_542162.1 CDS ygdD NC_007946.1 3095741 3096043 R hypothetical protein complement(3095741..3096043) Escherichia coli UTI89 3990279 YP_542163.1 CDS gcvA NC_007946.1 3096155 3097072 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3096155..3097072) Escherichia coli UTI89 3990280 YP_542164.1 CDS UTI89_C3181 NC_007946.1 3097390 3097683 D hypothetical protein 3097390..3097683 Escherichia coli UTI89 3990281 YP_542165.1 CDS UTI89_C3182 NC_007946.1 3097423 3097653 R hypothetical protein complement(3097423..3097653) Escherichia coli UTI89 3990282 YP_542166.1 CDS UTI89_C3183 NC_007946.1 3097806 3099047 D cysteine sulfinate desulfinase 3097806..3099047 Escherichia coli UTI89 3990283 YP_542167.1 CDS ygdK NC_007946.1 3099047 3099490 D hypothetical protein 3099047..3099490 Escherichia coli UTI89 3990284 YP_542168.1 CDS ygdL NC_007946.1 3099541 3100347 R hypothetical protein complement(3099541..3100347) Escherichia coli UTI89 3990285 YP_542169.2 CDS mltA NC_007946.1 3100424 3101521 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3100424..3101521) Escherichia coli UTI89 3990286 YP_542170.1 CDS UTI89_C3190 NC_007946.1 3102641 3103162 D hypothetical protein 3102641..3103162 Escherichia coli UTI89 3990290 YP_542171.1 CDS UTI89_C3191 NC_007946.1 3103215 3104759 D hypothetical protein 3103215..3104759 Escherichia coli UTI89 3993868 YP_542172.1 CDS UTI89_C3192 NC_007946.1 3104777 3106114 D hypothetical protein 3104777..3106114 Escherichia coli UTI89 3993869 YP_542173.1 CDS UTI89_C3193 NC_007946.1 3106111 3106776 D hypothetical protein 3106111..3106776 Escherichia coli UTI89 3993870 YP_542174.1 CDS UTI89_C3194 NC_007946.1 3106789 3108441 D hypothetical protein 3106789..3108441 Escherichia coli UTI89 3993871 YP_542175.1 CDS UTI89_C3195 NC_007946.1 3108478 3109080 R hypothetical protein complement(3108478..3109080) Escherichia coli UTI89 3993872 YP_542176.1 CDS UTI89_C3196 NC_007946.1 3108499 3108990 D secreted protein Hcp 3108499..3108990 Escherichia coli UTI89 3993873 YP_542177.1 CDS UTI89_C3197 NC_007946.1 3109182 3111827 D ClpB protein 3109182..3111827 Escherichia coli UTI89 3993874 YP_542178.1 CDS UTI89_C3198 NC_007946.1 3111839 3114319 D hypothetical protein 3111839..3114319 Escherichia coli UTI89 3993875 YP_542179.1 CDS UTI89_C3199 NC_007946.1 3114339 3116108 D hypothetical protein 3114339..3116108 Escherichia coli UTI89 3993876 YP_542180.1 CDS UTI89_C3200 NC_007946.1 3116083 3116916 D hypothetical protein 3116083..3116916 Escherichia coli UTI89 3993877 YP_542181.1 CDS UTI89_C3201 NC_007946.1 3116885 3117178 D hypothetical protein 3116885..3117178 Escherichia coli UTI89 3993878 YP_542182.1 CDS UTI89_C3202 NC_007946.1 3117642 3117902 D hypothetical protein 3117642..3117902 Escherichia coli UTI89 3993879 YP_542183.1 CDS UTI89_C3203 NC_007946.1 3117829 3119040 D hypothetical protein 3117829..3119040 Escherichia coli UTI89 3993880 YP_542184.1 CDS UTI89_C3204 NC_007946.1 3119050 3122403 D hypothetical protein 3119050..3122403 Escherichia coli UTI89 3993881 YP_542185.1 CDS UTI89_C3205 NC_007946.1 3122369 3124006 D hypothetical protein 3122369..3124006 Escherichia coli UTI89 3993882 YP_542186.1 CDS UTI89_C3206 NC_007946.1 3125577 3126218 D hypothetical protein 3125577..3126218 Escherichia coli UTI89 3993883 YP_542187.1 CDS UTI89_C3207 NC_007946.1 3126499 3126918 D hypothetical protein 3126499..3126918 Escherichia coli UTI89 3993884 YP_542188.1 CDS UTI89_C3208 NC_007946.1 3130072 3130608 D hypothetical protein 3130072..3130608 Escherichia coli UTI89 3993885 YP_542189.1 CDS UTI89_C3209 NC_007946.1 3130612 3131040 D hypothetical protein 3130612..3131040 Escherichia coli UTI89 3993886 YP_542190.1 CDS UTI89_C3210 NC_007946.1 3131040 3132416 D hypothetical protein 3131040..3132416 Escherichia coli UTI89 3993887 YP_542191.1 CDS UTI89_C3211 NC_007946.1 3131590 3131742 R hypothetical protein complement(3131590..3131742) Escherichia coli UTI89 3991203 YP_542192.1 CDS UTI89_C3212 NC_007946.1 3132718 3133674 R 2-hydroxyacid dehydrogenase complement(3132718..3133674) Escherichia coli UTI89 3991204 YP_542193.1 CDS UTI89_C3213 NC_007946.1 3133737 3134333 R phosphosugar isomerase complement(3133737..3134333) Escherichia coli UTI89 3991205 YP_542194.1 CDS UTI89_C3214 NC_007946.1 3134336 3135511 R beta-cystathionase complement(3134336..3135511) Escherichia coli UTI89 3991206 YP_542195.1 CDS UTI89_C3215 NC_007946.1 3135511 3137091 R PTS system maltose and glucose-specific transporter subunit IIABC complement(3135511..3137091) Escherichia coli UTI89 3991207 YP_542196.1 CDS UTI89_C3216 NC_007946.1 3137123 3137992 R antiterminator complement(3137123..3137992) Escherichia coli UTI89 3991208 YP_542197.1 CDS UTI89_C3217 NC_007946.1 3138031 3138183 D hypothetical protein 3138031..3138183 Escherichia coli UTI89 3991209 YP_542198.1 CDS amiC NC_007946.1 3138193 3139536 R N-acetylmuramoyl-L-alanine amidase complement(3138193..3139536) Escherichia coli UTI89 3991210 YP_542199.2 CDS argA NC_007946.1 3139678 3141009 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3139678..3141009 Escherichia coli UTI89 3991211 YP_542200.1 CDS recD NC_007946.1 3141071 3142897 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3141071..3142897) Escherichia coli UTI89 3991212 YP_542201.1 CDS recB NC_007946.1 3142897 3146448 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3142897..3146448) Escherichia coli UTI89 3991213 YP_542202.1 CDS ptrA NC_007946.1 3146432 3149320 R synonym: b2821, ptr; protease III complement(3146432..3149320) Escherichia coli UTI89 3991214 YP_542203.1 CDS recC NC_007946.1 3149496 3152864 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3149496..3152864) Escherichia coli UTI89 3991215 YP_542204.1 CDS ppdC NC_007946.1 3152877 3153200 R hypothetical protein complement(3152877..3153200) Escherichia coli UTI89 3991216 YP_542205.1 CDS ygdB NC_007946.1 3153185 3153592 R hypothetical protein complement(3153185..3153592) Escherichia coli UTI89 3991217 YP_542206.1 CDS ppdB NC_007946.1 3153589 3154176 R hypothetical protein complement(3153589..3154176) Escherichia coli UTI89 3991218 YP_542207.1 CDS ppdA NC_007946.1 3154143 3154613 R hypothetical protein complement(3154143..3154613) Escherichia coli UTI89 3991219 YP_542209.1 CDS thyA NC_007946.1 3154798 3155592 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3154798..3155592) Escherichia coli UTI89 3991221 YP_542210.1 CDS lgt NC_007946.1 3155599 3156474 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3155599..3156474) Escherichia coli UTI89 3994136 YP_542211.1 CDS ptsP NC_007946.1 3156625 3158871 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3156625..3158871) Escherichia coli UTI89 3994137 YP_542212.1 CDS nudH NC_007946.1 3158884 3159414 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3158884..3159414) Escherichia coli UTI89 3994138 YP_542213.1 CDS UTI89_C3233 NC_007946.1 3159767 3159913 R hypothetical protein complement(3159767..3159913) Escherichia coli UTI89 3994139 YP_542214.1 CDS mutH NC_007946.1 3160099 3160788 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3160099..3160788 Escherichia coli UTI89 3994140 YP_542215.1 CDS ygdQ NC_007946.1 3160857 3161570 D transport protein 3160857..3161570 Escherichia coli UTI89 3994141 YP_542216.1 CDS UTI89_C3236 NC_007946.1 3161642 3161929 R hypothetical protein complement(3161642..3161929) Escherichia coli UTI89 3994142 YP_542217.1 CDS ygdR NC_007946.1 3161708 3161926 D lipoprotein 3161708..3161926 Escherichia coli UTI89 3994143 YP_542218.1 CDS tas NC_007946.1 3162034 3163074 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo/keto reductase 3162034..3163074 Escherichia coli UTI89 3994144 YP_542219.1 CDS ygeD NC_007946.1 3163106 3164299 R lysophospholipid transporter LplT complement(3163106..3164299) Escherichia coli UTI89 3994145 YP_542220.1 CDS aas NC_007946.1 3164292 3166451 R AAS bifunctional protein; Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3164292..3166451) Escherichia coli UTI89 3994146 YP_542221.1 CDS galR NC_007946.1 3167037 3168068 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3167037..3168068 Escherichia coli UTI89 3994147 YP_542222.1 CDS lysA NC_007946.1 3168075 3169337 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3168075..3169337) Escherichia coli UTI89 3994148 YP_542223.1 CDS lysR NC_007946.1 3169459 3170394 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3169459..3170394 Escherichia coli UTI89 3994149 YP_542224.1 CDS ygeA NC_007946.1 3170381 3171073 R racemase complement(3170381..3171073) Escherichia coli UTI89 3994150 YP_542225.1 CDS UTI89_C3245 NC_007946.1 3172935 3173696 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3172935..3173696) Escherichia coli UTI89 3994151 YP_542226.1 CDS kduI NC_007946.1 3173726 3174562 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3173726..3174562) Escherichia coli UTI89 3994152 YP_542227.1 CDS yqeF NC_007946.1 3174849 3176033 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3174849..3176033) Escherichia coli UTI89 3994153 YP_542228.1 CDS UTI89_C3248 NC_007946.1 3176285 3177514 D transporter protein 3176285..3177514 Escherichia coli UTI89 3994154 YP_542229.1 CDS ygeR NC_007946.1 3177983 3178762 R lipoprotein YgeR complement(3177983..3178762) Escherichia coli UTI89 3990076 YP_542230.1 CDS UTI89_C3251 NC_007946.1 3179152 3181449 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3179152..3181449 Escherichia coli UTI89 3990077 YP_542231.1 CDS ygeT NC_007946.1 3181460 3182338 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3181460..3182338 Escherichia coli UTI89 3990078 YP_542232.1 CDS UTI89_C3253 NC_007946.1 3182335 3182814 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3182335..3182814 Escherichia coli UTI89 3990079 YP_542233.1 CDS ygeV NC_007946.1 3182854 3184632 R sigma-54-dependent transcriptional regulator ygeV complement(3182854..3184632) Escherichia coli UTI89 3990080 YP_542234.1 CDS ygeW NC_007946.1 3185108 3186298 D aspartate/ornithine carbamoyltransferase 3185108..3186298 Escherichia coli UTI89 3990081 YP_542235.1 CDS ygeX NC_007946.1 3186356 3187552 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3186356..3187552 Escherichia coli UTI89 3990082 YP_542236.1 CDS ygeY NC_007946.1 3187610 3188821 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3187610..3188821 Escherichia coli UTI89 3990083 YP_542237.1 CDS ygeZ NC_007946.1 3188862 3190259 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3188862..3190259 Escherichia coli UTI89 3990084 YP_542238.1 CDS yqeA NC_007946.1 3190307 3191239 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3190307..3191239 Escherichia coli UTI89 3990085 YP_542239.1 CDS yqeB NC_007946.1 3191280 3192905 R hypothetical protein complement(3191280..3192905) Escherichia coli UTI89 3990086 YP_542240.1 CDS yqeC NC_007946.1 3192953 3193723 R hypothetical protein complement(3192953..3193723) Escherichia coli UTI89 3990087 YP_542241.1 CDS ygfJ NC_007946.1 3193827 3194405 D hypothetical protein 3193827..3194405 Escherichia coli UTI89 3990088 YP_542242.1 CDS ygfK NC_007946.1 3194727 3197825 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3194727..3197825 Escherichia coli UTI89 3990089 YP_542243.1 CDS UTI89_C3264 NC_007946.1 3197828 3199156 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3197828..3199156 Escherichia coli UTI89 3990090 YP_542244.1 CDS ygfM NC_007946.1 3199207 3199986 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3199207..3199986 Escherichia coli UTI89 3990091 YP_542245.1 CDS xdhD NC_007946.1 3199983 3202853 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3199983..3202853 Escherichia coli UTI89 3990092 YP_542246.1 CDS ygfO NC_007946.1 3202961 3204418 D transport protein 3202961..3204418 Escherichia coli UTI89 3990093 YP_542247.1 CDS ygfP NC_007946.1 3204313 3205752 D Catalyzes the deamination of guanine; guanine deaminase 3204313..3205752 Escherichia coli UTI89 3992123 YP_542248.1 CDS UTI89_C3269 NC_007946.1 3205788 3207155 D hypothetical protein 3205788..3207155 Escherichia coli UTI89 3992124 YP_542249.1 CDS ygfS NC_007946.1 3207191 3207682 R electron transport protein YgfS complement(3207191..3207682) Escherichia coli UTI89 3992125 YP_542250.1 CDS ygfT NC_007946.1 3207679 3209613 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3207679..3209613) Escherichia coli UTI89 3992126 YP_542251.1 CDS ygfU NC_007946.1 3209905 3211482 D purine permease YgfU 3209905..3211482 Escherichia coli UTI89 3992127 YP_542252.1 CDS UTI89_C3273 NC_007946.1 3211466 3211609 D hypothetical protein 3211466..3211609 Escherichia coli UTI89 3992128 YP_542253.1 CDS UTI89_C3274 NC_007946.1 3211732 3212280 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3211732..3212280 Escherichia coli UTI89 3992129 YP_542254.1 CDS lysS NC_007946.1 3212323 3213840 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3212323..3213840) Escherichia coli UTI89 3992130 YP_542255.1 CDS UTI89_C3276 NC_007946.1 3212440 3213855 D hypothetical protein 3212440..3213855 Escherichia coli UTI89 3992131 YP_542256.1 CDS recJ NC_007946.1 3215039 3216772 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3215039..3216772) Escherichia coli UTI89 3992132 YP_542257.1 CDS dsbC NC_007946.1 3216778 3217488 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3216778..3217488) Escherichia coli UTI89 3992133 YP_542258.1 CDS xerD NC_007946.1 3217513 3218409 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3217513..3218409) Escherichia coli UTI89 3992134 YP_542259.1 CDS fldB NC_007946.1 3218521 3219042 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3218521..3219042 Escherichia coli UTI89 3992135 YP_542260.1 CDS ygfX NC_007946.1 3219082 3219489 R hypothetical protein complement(3219082..3219489) Escherichia coli UTI89 3992136 YP_542261.1 CDS ygfY NC_007946.1 3219470 3219736 R hypothetical protein complement(3219470..3219736) Escherichia coli UTI89 3992137 YP_542262.1 CDS UTI89_C3283 NC_007946.1 3219711 3219902 D hypothetical protein 3219711..3219902 Escherichia coli UTI89 3992138 YP_542263.1 CDS ygfZ NC_007946.1 3219979 3220959 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3219979..3220959 Escherichia coli UTI89 3992139 YP_542264.1 CDS UTI89_C3285 NC_007946.1 3221036 3221695 R oxidoreductase complement(3221036..3221695) Escherichia coli UTI89 3992140 YP_542265.1 CDS yqfB NC_007946.1 3221859 3222170 R hypothetical protein complement(3221859..3222170) Escherichia coli UTI89 3992141 YP_542266.1 CDS bglA NC_007946.1 3222191 3223648 D 6-phospho-beta-glucosidase 3222191..3223648 Escherichia coli UTI89 3992142 YP_542267.1 CDS gcvP NC_007946.1 3223814 3226687 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3223814..3226687) Escherichia coli UTI89 3990519 YP_542268.1 CDS gcvH NC_007946.1 3226805 3227197 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3226805..3227197) Escherichia coli UTI89 3990520 YP_542269.1 CDS gcvT NC_007946.1 3227218 3228312 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3227218..3228312) Escherichia coli UTI89 3990521 YP_542270.1 CDS UTI89_C3291 NC_007946.1 3228320 3228475 R hypothetical protein complement(3228320..3228475) Escherichia coli UTI89 3990522 YP_542271.1 CDS visC NC_007946.1 3228760 3229962 R hypothetical protein complement(3228760..3229962) Escherichia coli UTI89 3990523 YP_542272.1 CDS ubiH NC_007946.1 3229985 3231163 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3229985..3231163) Escherichia coli UTI89 3990524 YP_542273.1 CDS pepP NC_007946.1 3231160 3232485 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3231160..3232485) Escherichia coli UTI89 3990525 YP_542274.1 CDS ygfB NC_007946.1 3232511 3233095 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3232511..3233095) Escherichia coli UTI89 3990526 YP_542275.1 CDS UTI89_C3296 NC_007946.1 3233120 3233308 D hypothetical protein 3233120..3233308 Escherichia coli UTI89 3990527 YP_542276.1 CDS ygfE NC_007946.1 3233257 3233586 D Z-ring-associated protein 3233257..3233586 Escherichia coli UTI89 3990528 YP_542277.1 CDS ygfA NC_007946.1 3233688 3234434 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3233688..3234434 Escherichia coli UTI89 3990529 YP_542278.1 CDS serA NC_007946.1 3234824 3236056 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3234824..3236056) Escherichia coli UTI89 3990530 YP_542279.1 CDS rpiA NC_007946.1 3236312 3237043 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3236312..3237043) Escherichia coli UTI89 3990531 YP_542280.1 CDS yqfE NC_007946.1 3237027 3237305 R hypothetical protein complement(3237027..3237305) Escherichia coli UTI89 3990532 YP_542281.2 CDS iciA NC_007946.1 3237398 3238291 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3237398..3238291 Escherichia coli UTI89 3990533 YP_542282.1 CDS UTI89_C3303 NC_007946.1 3238494 3239549 D hypothetical protein 3238494..3239549 Escherichia coli UTI89 3990534 YP_542283.1 CDS ygfI NC_007946.1 3239546 3240442 R transcriptional regulator YgfI complement(3239546..3240442) Escherichia coli UTI89 3990535 YP_542284.1 CDS yggE NC_007946.1 3240600 3241340 R hypothetical protein complement(3240600..3241340) Escherichia coli UTI89 3990536 YP_542285.1 CDS yggA NC_007946.1 3241433 3242065 R Involved in the export of arginine; arginine exporter protein complement(3241433..3242065) Escherichia coli UTI89 3990537 YP_542286.1 CDS yggB NC_007946.1 3242204 3243064 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive ion channel MscS complement(3242204..3243064) Escherichia coli UTI89 3990538 YP_542287.1 CDS fba NC_007946.1 3243255 3244418 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3243255..3244418) Escherichia coli UTI89 3990539 YP_542288.1 CDS pgk NC_007946.1 3244549 3245775 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3244549..3245775) Escherichia coli UTI89 3990540 YP_542289.1 CDS epd NC_007946.1 3245762 3246865 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3245762..3246865) Escherichia coli UTI89 3990541 YP_542290.1 CDS UTI89_C3311 NC_007946.1 3247153 3247584 D hypothetical protein 3247153..3247584 Escherichia coli UTI89 3990542 YP_542291.1 CDS UTI89_C3312 NC_007946.1 3247607 3248185 D hypothetical protein 3247607..3248185 Escherichia coli UTI89 3990543 YP_542292.1 CDS UTI89_C3313 NC_007946.1 3248186 3248893 D hypothetical protein 3248186..3248893 Escherichia coli UTI89 3990544 YP_542293.1 CDS UTI89_C3314 NC_007946.1 3249022 3249558 D ATP-binding protein of ABC transport system 3249022..3249558 Escherichia coli UTI89 3990545 YP_542294.1 CDS UTI89_C3315 NC_007946.1 3249519 3250229 D ATP-binding protein of ABC transport system 3249519..3250229 Escherichia coli UTI89 3990546 YP_542295.1 CDS frcK NC_007946.1 3250201 3250914 R fructose transport system kinase complement(3250201..3250914) Escherichia coli UTI89 3990547 YP_542296.1 CDS yggD NC_007946.1 3250911 3251420 R DNA-binding transcriptional regulator complement(3250911..3251420) Escherichia coli UTI89 3990548 YP_542297.1 CDS UTI89_C3318 NC_007946.1 3251569 3251757 R hypothetical protein complement(3251569..3251757) Escherichia coli UTI89 3990549 YP_542298.1 CDS UTI89_C3319 NC_007946.1 3251754 3253031 R oxidoreductase complement(3251754..3253031) Escherichia coli UTI89 3990550 YP_542299.1 CDS cmtA NC_007946.1 3253046 3254434 R PTS system mannitol (cryptic)-specific transporter subunit IIBC complement(3253046..3254434) Escherichia coli UTI89 3990551 YP_542300.1 CDS cmtB NC_007946.1 3254462 3254905 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3254462..3254905) Escherichia coli UTI89 3990552 YP_542301.1 CDS UTI89_C3322 NC_007946.1 3255282 3256190 D SPFH domain-containing protein 3255282..3256190 Escherichia coli UTI89 3990553 YP_542302.2 CDS tktA NC_007946.1 3256410 3258401 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3256410..3258401) Escherichia coli UTI89 3990554 YP_542303.1 CDS yggG NC_007946.1 3258460 3259437 D metalloprotease YggG 3258460..3259437 Escherichia coli UTI89 3990555 YP_542304.1 CDS speB NC_007946.1 3259641 3260561 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3259641..3260561) Escherichia coli UTI89 3990556 YP_542305.1 CDS UTI89_C3326 NC_007946.1 3260697 3261428 R hypothetical protein complement(3260697..3261428) Escherichia coli UTI89 3990557 YP_542306.1 CDS speA NC_007946.1 3261574 3263562 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3261574..3263562) Escherichia coli UTI89 3992658 YP_542307.1 CDS yqgB NC_007946.1 3263559 3263705 R hypothetical protein complement(3263559..3263705) Escherichia coli UTI89 3992659 YP_542308.1 CDS yqgC NC_007946.1 3263826 3264041 D hypothetical protein 3263826..3264041 Escherichia coli UTI89 3992660 YP_542309.1 CDS yqgD NC_007946.1 3264038 3264304 R hypothetical protein complement(3264038..3264304) Escherichia coli UTI89 3992661 YP_542310.2 CDS metK NC_007946.1 3264345 3265499 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3264345..3265499 Escherichia coli UTI89 3992662 YP_542311.1 CDS galP NC_007946.1 3265924 3267330 D galactose-proton symporter 3265924..3267330 Escherichia coli UTI89 3992663 YP_542312.1 CDS sprT NC_007946.1 3267407 3267904 D hypothetical protein 3267407..3267904 Escherichia coli UTI89 3992664 YP_542313.1 CDS endA NC_007946.1 3267996 3268706 D endonuclease I 3267996..3268706 Escherichia coli UTI89 3992665 YP_542314.2 CDS yggJ NC_007946.1 3268786 3269517 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3268786..3269517 Escherichia coli UTI89 3992666 YP_542315.1 CDS gshB NC_007946.1 3269530 3270480 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3269530..3270480 Escherichia coli UTI89 3992667 YP_542316.1 CDS yqgE NC_007946.1 3270517 3271152 D hypothetical protein 3270517..3271152 Escherichia coli UTI89 3992668 YP_542317.1 CDS UTI89_C3338 NC_007946.1 3271152 3271568 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3271152..3271568 Escherichia coli UTI89 3992669 YP_542318.1 CDS yggR NC_007946.1 3271742 3272797 R hypothetical protein complement(3271742..3272797) Escherichia coli UTI89 3992670 YP_542319.1 CDS yggS NC_007946.1 3272740 3273444 D hypothetical protein 3272740..3273444 Escherichia coli UTI89 3992671 YP_542320.1 CDS yggT NC_007946.1 3273462 3274028 D resistance protein 3273462..3274028 Escherichia coli UTI89 3992672 YP_542321.1 CDS yggU NC_007946.1 3274013 3274315 D hypothetical protein 3274013..3274315 Escherichia coli UTI89 3992673 YP_542322.1 CDS yggV NC_007946.1 3274323 3274916 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3274323..3274916 Escherichia coli UTI89 3992674 YP_542323.1 CDS yggW NC_007946.1 3274909 3276045 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3274909..3276045 Escherichia coli UTI89 3992675 YP_542324.1 CDS yggM NC_007946.1 3276114 3277121 R hypothetical protein complement(3276114..3277121) Escherichia coli UTI89 3992676 YP_542325.1 CDS ansB NC_007946.1 3277238 3278284 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3277238..3278284) Escherichia coli UTI89 3992912 YP_542326.1 CDS yggN NC_007946.1 3278460 3279179 R hypothetical protein complement(3278460..3279179) Escherichia coli UTI89 3992913 YP_542327.1 CDS UTI89_C3348 NC_007946.1 3279200 3279340 R hypothetical protein complement(3279200..3279340) Escherichia coli UTI89 3992914 YP_542328.2 CDS yggL NC_007946.1 3279363 3279689 R hypothetical protein complement(3279363..3279689) Escherichia coli UTI89 3992915 YP_542329.1 CDS trmB NC_007946.1 3279689 3280408 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3279689..3280408) Escherichia coli UTI89 3992916 YP_542330.1 CDS mutY NC_007946.1 3280539 3281621 D adenine DNA glycosylase 3280539..3281621 Escherichia coli UTI89 3992917 YP_542331.1 CDS UTI89_C3352 NC_007946.1 3281598 3281891 R hypothetical protein complement(3281598..3281891) Escherichia coli UTI89 3992918 YP_542332.1 CDS yggX NC_007946.1 3281649 3281924 D hypothetical protein 3281649..3281924 Escherichia coli UTI89 3992919 YP_542333.1 CDS mltC NC_007946.1 3281986 3283068 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3281986..3283068 Escherichia coli UTI89 3992920 YP_542334.1 CDS nupG NC_007946.1 3283222 3284526 D transport of nucleosides, permease 3283222..3284526 Escherichia coli UTI89 3992921 YP_542335.1 CDS speC NC_007946.1 3284575 3286710 R ornithine decarboxylase complement(3284575..3286710) Escherichia coli UTI89 3992922 YP_542336.1 CDS UTI89_C3357 NC_007946.1 3286791 3286994 R hypothetical protein complement(3286791..3286994) Escherichia coli UTI89 3992923 YP_542337.1 CDS yqgA NC_007946.1 3287109 3287816 D hypothetical protein 3287109..3287816 Escherichia coli UTI89 3992924 YP_542338.1 CDS UTI89_C3360 NC_007946.1 3288222 3288377 D hypothetical protein 3288222..3288377 Escherichia coli UTI89 3992926 YP_542339.1 CDS UTI89_C3361 NC_007946.1 3288545 3288688 R hypothetical protein complement(3288545..3288688) Escherichia coli UTI89 3992927 YP_542340.1 CDS kpsF NC_007946.1 3289151 3290170 D polysialic acid capsule synthesis protein KpsF 3289151..3290170 Escherichia coli UTI89 3992928 YP_542341.1 CDS kpsE NC_007946.1 3290242 3291390 D polysialic acid capsule synthesis protein KpsE 3290242..3291390 Escherichia coli UTI89 3992929 YP_542342.1 CDS kpsD NC_007946.1 3291411 3293090 D polysialic acid transport protein KpsD 3291411..3293090 Escherichia coli UTI89 3992930 YP_542343.1 CDS kpsU NC_007946.1 3293100 3293840 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3293100..3293840 Escherichia coli UTI89 3991873 YP_542344.1 CDS kpsC NC_007946.1 3293837 3295864 D capsule polysaccharide export protein KpsC 3293837..3295864 Escherichia coli UTI89 3991874 YP_542345.1 CDS kpsS NC_007946.1 3295899 3297104 D polysialic acid capsule synthesis protein KpsS 3295899..3297104 Escherichia coli UTI89 3991875 YP_542346.1 CDS neuS NC_007946.1 3297254 3298483 R poly-alpha-2,8 sialosyl sialyltransferase complement(3297254..3298483) Escherichia coli UTI89 3991876 YP_542347.1 CDS neuE NC_007946.1 3298473 3299621 R NeuE protein complement(3298473..3299621) Escherichia coli UTI89 3991877 YP_542348.1 CDS neuC NC_007946.1 3299614 3300789 R polysialic acid biosynthesis protein P7 complement(3299614..3300789) Escherichia coli UTI89 3991878 YP_542349.1 CDS neuA NC_007946.1 3300786 3302042 R acylneuraminate cytidylyltransferase complement(3300786..3302042) Escherichia coli UTI89 3991879 YP_542350.1 CDS neuB NC_007946.1 3302042 3303082 R sialic acid synthase NeuB complement(3302042..3303082) Escherichia coli UTI89 3991880 YP_542351.1 CDS neuD NC_007946.1 3303079 3303702 R sialic acid synthase NeuD complement(3303079..3303702) Escherichia coli UTI89 3991881 YP_542352.1 CDS kpsT NC_007946.1 3303752 3304411 R polysialic acid transport ATP-binding protein kpsT complement(3303752..3304411) Escherichia coli UTI89 3991882 YP_542353.1 CDS kpsM NC_007946.1 3304408 3305184 R polysialic acid transport protein KpsM complement(3304408..3305184) Escherichia coli UTI89 3991883 YP_542354.1 CDS gspM NC_007946.1 3306242 3306778 R general secretion pathway protein YghD complement(3306242..3306778) Escherichia coli UTI89 3991884 YP_542355.2 CDS gspL NC_007946.1 3306780 3307640 R similar to general secretory pathway protein L; GspL-like protein complement(3306780..3307640) Escherichia coli UTI89 3991885 YP_542356.1 CDS gspK NC_007946.1 3307955 3308932 R hypothetical protein complement(3307955..3308932) Escherichia coli UTI89 3991886 YP_542357.1 CDS gspJ NC_007946.1 3308929 3309498 R type II secretion protein GspJ complement(3308929..3309498) Escherichia coli UTI89 3991887 YP_542358.1 CDS gspI NC_007946.1 3309531 3309902 R type II secretion protein GspI complement(3309531..3309902) Escherichia coli UTI89 3991888 YP_542359.1 CDS gspH NC_007946.1 3309899 3310462 R type II secretion protein GspH complement(3309899..3310462) Escherichia coli UTI89 3991889 YP_542360.1 CDS gspG NC_007946.1 3310466 3310921 R type II secretion protein GspG complement(3310466..3310921) Escherichia coli UTI89 3991890 YP_542361.1 CDS gspF NC_007946.1 3310938 3312161 R type II secretion protein GspF complement(3310938..3312161) Escherichia coli UTI89 3991891 YP_542362.1 CDS gspE NC_007946.1 3312161 3313654 R type II secretion protein GspE complement(3312161..3313654) Escherichia coli UTI89 3991951 YP_542363.1 CDS gspD NC_007946.1 3313654 3315714 R type II secretion protein GspD complement(3313654..3315714) Escherichia coli UTI89 3991952 YP_542364.1 CDS gspC NC_007946.1 3315744 3316574 R part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC complement(3315744..3316574) Escherichia coli UTI89 3991953 YP_542365.1 CDS yghG NC_007946.1 3316721 3317131 R lipoprotein complement(3316721..3317131) Escherichia coli UTI89 3991954 YP_542366.1 CDS pppA NC_007946.1 3317197 3318006 R prepilin peptidase A complement(3317197..3318006) Escherichia coli UTI89 3991955 YP_542367.1 CDS yghJ NC_007946.1 3318170 3322732 R lipoprotein AcfD-like complement(3318170..3322732) Escherichia coli UTI89 3991956 YP_542368.1 CDS UTI89_C3390 NC_007946.1 3322883 3323188 D hypothetical protein 3322883..3323188 Escherichia coli UTI89 3991957 YP_542369.1 CDS glcA NC_007946.1 3323216 3324898 R glycolate transporter complement(3323216..3324898) Escherichia coli UTI89 3991958 YP_542370.1 CDS glcB NC_007946.1 3325254 3327425 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3325254..3327425) Escherichia coli UTI89 3991959 YP_542371.1 CDS glcG NC_007946.1 3327447 3327869 R hypothetical protein complement(3327447..3327869) Escherichia coli UTI89 3991960 YP_542372.1 CDS glcD NC_007946.1 3330142 3331641 R glycolate oxidase subunit GlcD complement(3330142..3331641) Escherichia coli UTI89 3991961 YP_542373.1 CDS glcC NC_007946.1 3331832 3332656 D DNA-binding transcriptional regulator GlcC 3331832..3332656 Escherichia coli UTI89 3991962 YP_542374.1 CDS UTI89_C3396 NC_007946.1 3332663 3333805 R hypothetical protein complement(3332663..3333805) Escherichia coli UTI89 3991963 YP_542375.1 CDS UTI89_C3397 NC_007946.1 3334167 3335900 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3334167..3335900 Escherichia coli UTI89 3991964 YP_542376.1 CDS UTI89_C3398 NC_007946.1 3335897 3336811 D hypothetical protein 3335897..3336811 Escherichia coli UTI89 3991965 YP_542377.1 CDS UTI89_C3399 NC_007946.1 3336843 3337091 D acyl carrier protein 3336843..3337091 Escherichia coli UTI89 3991966 YP_542378.1 CDS UTI89_C3400 NC_007946.1 3337091 3338263 D hypothetical protein 3337091..3338263 Escherichia coli UTI89 3991967 YP_542379.1 CDS UTI89_C3401 NC_007946.1 3338298 3339458 R hypothetical protein complement(3338298..3339458) Escherichia coli UTI89 3991968 YP_542380.1 CDS UTI89_C3402 NC_007946.1 3339374 3340444 R hypothetical protein complement(3339374..3340444) Escherichia coli UTI89 3991969 YP_542381.1 CDS UTI89_C3403 NC_007946.1 3340475 3341035 R protein YtfJ complement(3340475..3341035) Escherichia coli UTI89 3991970 YP_542382.1 CDS UTI89_C3404 NC_007946.1 3341035 3341871 R hypothetical protein complement(3341035..3341871) Escherichia coli UTI89 3994462 YP_542383.1 CDS yghQ NC_007946.1 3341871 3343220 R hypothetical protein complement(3341871..3343220) Escherichia coli UTI89 3994463 YP_542384.1 CDS yghR NC_007946.1 3343266 3344036 R hypothetical protein complement(3343266..3344036) Escherichia coli UTI89 3994464 YP_542385.1 CDS yghS NC_007946.1 3344056 3344769 R ATP-binding protein YghS complement(3344056..3344769) Escherichia coli UTI89 3994465 YP_542386.1 CDS yghT NC_007946.1 3344944 3345636 D ATP-binding protein YghT 3344944..3345636 Escherichia coli UTI89 3994466 YP_542387.1 CDS pitB NC_007946.1 3345685 3347184 R inorganic phosphate transporter complement(3345685..3347184) Escherichia coli UTI89 3994467 YP_542388.1 CDS gsp NC_007946.1 3347476 3349338 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3347476..3349338) Escherichia coli UTI89 3994468 YP_542389.1 CDS yghU NC_007946.1 3349492 3350406 D YghU; B2989; one of eight glutathione transferases from E. coli; glutathione S-transferase YghU 3349492..3350406 Escherichia coli UTI89 3994469 YP_542390.1 CDS hybG NC_007946.1 3350539 3350787 R hydrogenase 2 accessory protein HypG complement(3350539..3350787) Escherichia coli UTI89 3994470 YP_542391.1 CDS hybF NC_007946.1 3350800 3351141 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3350800..3351141) Escherichia coli UTI89 3994471 YP_542392.1 CDS hybE NC_007946.1 3351134 3351622 R hydrogenase 2-specific chaperone complement(3351134..3351622) Escherichia coli UTI89 3994472 YP_542393.1 CDS hybD NC_007946.1 3351615 3352109 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3351615..3352109) Escherichia coli UTI89 3994473 YP_542394.1 CDS hybC NC_007946.1 3352109 3353812 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3352109..3353812) Escherichia coli UTI89 3994474 YP_542395.1 CDS hybB NC_007946.1 3353809 3354987 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3353809..3354987) Escherichia coli UTI89 3994475 YP_542396.1 CDS hybA NC_007946.1 3354977 3355963 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3354977..3355963) Escherichia coli UTI89 3994476 YP_542397.1 CDS UTI89_C3419 NC_007946.1 3355966 3357084 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3355966..3357084) Escherichia coli UTI89 3994477 YP_542398.1 CDS yghW NC_007946.1 3357273 3357560 R hypothetical protein complement(3357273..3357560) Escherichia coli UTI89 3994478 YP_542399.1 CDS UTI89_C3421 NC_007946.1 3357679 3358605 R hypothetical protein complement(3357679..3358605) Escherichia coli UTI89 3994479 YP_542400.1 CDS yghZ NC_007946.1 3358723 3359763 D aldo/keto reductase 3358723..3359763 Escherichia coli UTI89 3994480 YP_542401.1 CDS yqhA NC_007946.1 3359803 3360327 R hypothetical protein complement(3359803..3360327) Escherichia coli UTI89 3991461 YP_542402.1 CDS yghA NC_007946.1 3360485 3361372 D oxidoreductase 3360485..3361372 Escherichia coli UTI89 3991462 YP_542403.1 CDS exbD NC_007946.1 3361411 3361836 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3361411..3361836) Escherichia coli UTI89 3991463 YP_542404.1 CDS exbB NC_007946.1 3361843 3362577 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3361843..3362577) Escherichia coli UTI89 3991464 YP_542405.1 CDS UTI89_C3427 NC_007946.1 3362570 3362725 R hypothetical protein complement(3362570..3362725) Escherichia coli UTI89 3991465 YP_542406.1 CDS metC NC_007946.1 3362694 3364016 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3362694..3364016 Escherichia coli UTI89 3991466 YP_542407.1 CDS yghB NC_007946.1 3364156 3364815 D hypothetical protein 3364156..3364815 Escherichia coli UTI89 3991467 YP_542408.1 CDS yqhC NC_007946.1 3364855 3365982 R transcriptional regulator YqhC complement(3364855..3365982) Escherichia coli UTI89 3991468 YP_542409.1 CDS yqhD NC_007946.1 3365948 3367111 D oxidoreductase YqhD 3365948..3367111 Escherichia coli UTI89 3991469 YP_542410.1 CDS dkgA NC_007946.1 3367216 3368043 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3367216..3368043 Escherichia coli UTI89 3991470 YP_542411.1 CDS yqhG NC_007946.1 3368243 3369169 D hypothetical protein 3368243..3369169 Escherichia coli UTI89 3991471 YP_542412.1 CDS yqhH NC_007946.1 3369220 3369477 D outer membrane lipoprotein 3369220..3369477 Escherichia coli UTI89 3991472 YP_542413.1 CDS UTI89_C3435 NC_007946.1 3369519 3371738 R hypothetical protein complement(3369519..3371738) Escherichia coli UTI89 3991473 YP_542414.1 CDS UTI89_C3436 NC_007946.1 3371990 3372739 D regulator 3371990..3372739 Escherichia coli UTI89 3991474 YP_542415.1 CDS UTI89_C3437 NC_007946.1 3373026 3374534 D oxidoreductase YdfI 3373026..3374534 Escherichia coli UTI89 3991475 YP_542416.1 CDS UTI89_C3438 NC_007946.1 3374531 3375547 D zinc-type alcohol dehydrogenase-like protein YjjN 3374531..3375547 Escherichia coli UTI89 3991476 YP_542417.1 CDS UTI89_C3439 NC_007946.1 3375558 3376568 D ureidoglycolate dehydrogenase 3375558..3376568 Escherichia coli UTI89 3991477 YP_542418.1 CDS UTI89_C3440 NC_007946.1 3376641 3377624 D c4-dicarboxylate transport system binding protein 3376641..3377624 Escherichia coli UTI89 3991478 YP_542419.1 CDS UTI89_C3441 NC_007946.1 3377666 3378148 D hypothetical protein 3377666..3378148 Escherichia coli UTI89 3991479 YP_542420.1 CDS ygiK NC_007946.1 3378117 3379463 D c4-dicarboxylate permease 3378117..3379463 Escherichia coli UTI89 3991480 YP_542421.1 CDS sufI NC_007946.1 3379534 3380946 R repressor protein for FtsI complement(3379534..3380946) Escherichia coli UTI89 3991815 YP_542422.1 CDS plsC NC_007946.1 3381021 3381758 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3381021..3381758) Escherichia coli UTI89 3991816 YP_542423.1 CDS UTI89_C3445 NC_007946.1 3381807 3381962 R hypothetical protein complement(3381807..3381962) Escherichia coli UTI89 3991817 YP_542424.1 CDS parC NC_007946.1 3381993 3384251 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3381993..3384251) Escherichia coli UTI89 3991818 YP_542425.1 CDS UTI89_C3447 NC_007946.1 3384389 3386059 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; binding protein complement(3384389..3386059) Escherichia coli UTI89 3991819 YP_542426.1 CDS ygiV NC_007946.1 3386105 3386587 R hypothetical protein complement(3386105..3386587) Escherichia coli UTI89 3991820 YP_542427.1 CDS ygiW NC_007946.1 3386640 3387089 R hypothetical protein complement(3386640..3387089) Escherichia coli UTI89 3991821 YP_542428.1 CDS ygiX NC_007946.1 3387184 3387843 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3387184..3387843 Escherichia coli UTI89 3991822 YP_542429.1 CDS qseC NC_007946.1 3387840 3389189 D synonym: b3026, ygiO, G7576, ygiY; sensor protein QseC 3387840..3389189 Escherichia coli UTI89 3991823 YP_542430.1 CDS UTI89_C3452 NC_007946.1 3389235 3389567 R hypothetical protein complement(3389235..3389567) Escherichia coli UTI89 3991824 YP_542431.1 CDS UTI89_C3453 NC_007946.1 3389574 3390311 R hypothetical protein complement(3389574..3390311) Escherichia coli UTI89 3991825 YP_542432.1 CDS UTI89_C3454 NC_007946.1 3390287 3390766 R hypothetical protein complement(3390287..3390766) Escherichia coli UTI89 3991826 YP_542433.1 CDS mdaB NC_007946.1 3391016 3391597 D modulator of drug activity B 3391016..3391597 Escherichia coli UTI89 3991827 YP_542434.1 CDS UTI89_C3456 NC_007946.1 3391622 3391945 R hypothetical protein complement(3391622..3391945) Escherichia coli UTI89 3991828 YP_542435.1 CDS ygiN NC_007946.1 3391628 3391942 D protein YgiN 3391628..3391942 Escherichia coli UTI89 3991829 YP_542436.1 CDS UTI89_C3458 NC_007946.1 3391987 3392874 R hypothetical protein complement(3391987..3392874) Escherichia coli UTI89 3991830 YP_542437.1 CDS UTI89_C3459 NC_007946.1 3392871 3393881 R iron ABC transporter substrate-binding protein complement(3392871..3393881) Escherichia coli UTI89 3991831 YP_542438.1 CDS UTI89_C3460 NC_007946.1 3393829 3394878 R iron ABC transporter permease complement(3393829..3394878) Escherichia coli UTI89 3991832 YP_542439.1 CDS UTI89_C3461 NC_007946.1 3394875 3395858 R iron ABC transporter permease complement(3394875..3395858) Escherichia coli UTI89 3991833 YP_542440.1 CDS UTI89_C3462 NC_007946.1 3395855 3396664 R ferric enterobactin transport ATP-binding protein fepC complement(3395855..3396664) Escherichia coli UTI89 3993158 YP_542441.1 CDS UTI89_C3463 NC_007946.1 3397038 3399179 D iron compound receptor 3397038..3399179 Escherichia coli UTI89 3993159 YP_542442.1 CDS parE NC_007946.1 3399243 3401135 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3399243..3401135) Escherichia coli UTI89 3993160 YP_542443.1 CDS yqiA NC_007946.1 3401164 3401745 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(3401164..3401745) Escherichia coli UTI89 3993161 YP_542444.1 CDS icc NC_007946.1 3401745 3402572 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3401745..3402572) Escherichia coli UTI89 3993162 YP_542445.1 CDS yqiB NC_007946.1 3402597 3403019 R hypothetical protein complement(3402597..3403019) Escherichia coli UTI89 3993163 YP_542446.1 CDS nudF NC_007946.1 3403020 3403649 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase complement(3403020..3403649) Escherichia coli UTI89 3993164 YP_542447.1 CDS tolC NC_007946.1 3403815 3405335 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3403815..3405335 Escherichia coli UTI89 3993165 YP_542448.1 CDS ygiA NC_007946.1 3405332 3405595 D hypothetical protein 3405332..3405595 Escherichia coli UTI89 3993166 YP_542449.2 CDS ygiB NC_007946.1 3405483 3406154 D hypothetical protein 3405483..3406154 Escherichia coli UTI89 3993167 YP_542450.1 CDS ygiC NC_007946.1 3406160 3407320 D synthetase/amidase 3406160..3407320 Escherichia coli UTI89 3993168 YP_542451.1 CDS asst NC_007946.1 3407805 3409601 D arylsulfate sulfotransferase 3407805..3409601 Escherichia coli UTI89 3993169 YP_542452.1 CDS UTI89_C3474 NC_007946.1 3409619 3410287 D disulfide isomerase 3409619..3410287 Escherichia coli UTI89 3993170 YP_542453.1 CDS UTI89_C3475 NC_007946.1 3410302 3410973 D disulfide oxidoreductase 3410302..3410973 Escherichia coli UTI89 3993171 YP_542454.1 CDS ygiD NC_007946.1 3411019 3411834 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3411019..3411834) Escherichia coli UTI89 3993172 YP_542455.1 CDS zupT NC_007946.1 3411908 3412723 D synonym: ygiE, b3040; zinc transporter ZupT 3411908..3412723 Escherichia coli UTI89 3993173 YP_542456.1 CDS UTI89_C3478 NC_007946.1 3412785 3412970 R hypothetical protein complement(3412785..3412970) Escherichia coli UTI89 3993174 YP_542457.1 CDS ygiL NC_007946.1 3413527 3414090 D fimbrial protein 3413527..3414090 Escherichia coli UTI89 3993175 YP_542458.1 CDS yqiG NC_007946.1 3414177 3416699 D outer membrane usher protein YqiG 3414177..3416699 Escherichia coli UTI89 3993176 YP_542459.1 CDS yqiH NC_007946.1 3416706 3417455 D periplasmic chaperone YqiH 3416706..3417455 Escherichia coli UTI89 3993177 YP_542460.1 CDS UTI89_C3482 NC_007946.1 3417452 3418501 D Yqi fimbrial adhesin 3417452..3418501 Escherichia coli UTI89 3993888 YP_542461.1 CDS ribB NC_007946.1 3418555 3419208 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3418555..3419208) Escherichia coli UTI89 3993889 YP_542462.1 CDS yqiC NC_007946.1 3419522 3419881 D hypothetical protein 3419522..3419881 Escherichia coli UTI89 3993890 YP_542463.1 CDS glgS NC_007946.1 3419916 3420122 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3419916..3420122) Escherichia coli UTI89 3993891 YP_542464.1 CDS yqiJ NC_007946.1 3420386 3421015 D hypothetical protein 3420386..3421015 Escherichia coli UTI89 3993892 YP_542465.1 CDS yqiK NC_007946.1 3421042 3422703 D hypothetical protein 3421042..3422703 Escherichia coli UTI89 3993893 YP_542466.1 CDS UTI89_C3488 NC_007946.1 3423122 3424555 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3423122..3424555) Escherichia coli UTI89 3993894 YP_542467.2 CDS glnE NC_007946.1 3424603 3427443 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3424603..3427443) Escherichia coli UTI89 3993895 YP_542468.1 CDS ygiF NC_007946.1 3427466 3428767 R hypothetical protein complement(3427466..3428767) Escherichia coli UTI89 3993896 YP_542469.1 CDS ygiM NC_007946.1 3429009 3429629 D signal transduction protein 3429009..3429629 Escherichia coli UTI89 3993897 YP_542470.1 CDS cca NC_007946.1 3429693 3430931 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3429693..3430931 Escherichia coli UTI89 3993898 YP_542471.1 CDS bacA NC_007946.1 3431119 3431943 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3431119..3431943) Escherichia coli UTI89 3993899 YP_542472.1 CDS folB NC_007946.1 3432031 3432402 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3432031..3432402) Escherichia coli UTI89 3993900 YP_542473.1 CDS ygiH NC_007946.1 3432504 3433121 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3432504..3433121 Escherichia coli UTI89 3993901 YP_542474.1 CDS ygiP NC_007946.1 3433134 3434114 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3433134..3434114) Escherichia coli UTI89 3993902 YP_542475.1 CDS ttdA NC_007946.1 3434273 3435184 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3434273..3435184 Escherichia coli UTI89 3993903 YP_542476.1 CDS ttdB NC_007946.1 3435181 3435786 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3435181..3435786 Escherichia coli UTI89 3993904 YP_542477.1 CDS ygjE NC_007946.1 3435834 3437297 D tartrate carrier/transporter 3435834..3437297 Escherichia coli UTI89 3993905 YP_542478.1 CDS ygjD NC_007946.1 3437340 3438353 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3437340..3438353) Escherichia coli UTI89 3993906 YP_542479.1 CDS UTI89_C3501 NC_007946.1 3438362 3438649 R hypothetical protein complement(3438362..3438649) Escherichia coli UTI89 3992143 YP_542480.1 CDS rpsU NC_007946.1 3438591 3438806 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3438591..3438806 Escherichia coli UTI89 3992144 YP_542481.1 CDS dnaG NC_007946.1 3438917 3440662 D synthesizes RNA primers at the replication forks; DNA primase 3438917..3440662 Escherichia coli UTI89 3992145 YP_542482.1 CDS UTI89_C3504 NC_007946.1 3440676 3440798 D hypothetical protein 3440676..3440798 Escherichia coli UTI89 3992146 YP_542483.1 CDS rpoD NC_007946.1 3440857 3442698 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3440857..3442698 Escherichia coli UTI89 3992147 YP_542484.1 CDS ygjF NC_007946.1 3442777 3443283 R G/U mismatch-specific DNA glycosylase complement(3442777..3443283) Escherichia coli UTI89 3992148 YP_542485.1 CDS yqjH NC_007946.1 3443537 3444301 R hypothetical protein complement(3443537..3444301) Escherichia coli UTI89 3992150 YP_542486.1 CDS yqjI NC_007946.1 3444578 3445201 D hypothetical protein 3444578..3445201 Escherichia coli UTI89 3992151 YP_542487.1 CDS aer NC_007946.1 3445355 3446875 R aerotaxis sensor receptor, flavoprotein complement(3445355..3446875) Escherichia coli UTI89 3992152 YP_542488.2 CDS ygjG NC_007946.1 3447266 3448672 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3447266..3448672 Escherichia coli UTI89 3992153 YP_542489.1 CDS UTI89_C3512 NC_007946.1 3448656 3449066 D hypothetical protein 3448656..3449066 Escherichia coli UTI89 3992154 YP_542490.1 CDS ygjH NC_007946.1 3448714 3449046 R hypothetical protein complement(3448714..3449046) Escherichia coli UTI89 3992155 YP_542491.1 CDS UTI89_C3514 NC_007946.1 3449153 3449335 D hypothetical protein 3449153..3449335 Escherichia coli UTI89 3992156 YP_542492.1 CDS ebgR NC_007946.1 3449265 3450248 D DNA-binding transcriptional repressor EbgR 3449265..3450248 Escherichia coli UTI89 3992157 YP_542493.1 CDS ebgA NC_007946.1 3450255 3453524 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3450255..3453524 Escherichia coli UTI89 3992158 YP_542494.1 CDS ebgC NC_007946.1 3453521 3453970 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3453521..3453970 Escherichia coli UTI89 3992159 YP_542495.1 CDS ygjI NC_007946.1 3454033 3455466 D oxidoreductase 3454033..3455466 Escherichia coli UTI89 3992160 YP_542496.1 CDS ygjJ NC_007946.1 3455600 3456670 D hypothetical protein 3455600..3456670 Escherichia coli UTI89 3992161 YP_542497.1 CDS ygjK NC_007946.1 3456687 3459038 D glycosyl hydrolase 3456687..3459038 Escherichia coli UTI89 3990113 YP_542498.1 CDS ygjL NC_007946.1 3459209 3461227 D NADPH 2,4-dienoyl-CoA reductase 3459209..3461227 Escherichia coli UTI89 3990114 YP_542499.1 CDS ygjO NC_007946.1 3461345 3462481 R ribosomal RNA small subunit methyltransferase D complement(3461345..3462481) Escherichia coli UTI89 3990115 YP_542500.1 CDS ygjP NC_007946.1 3462530 3463069 D hypothetical protein 3462530..3463069 Escherichia coli UTI89 3990116 YP_542501.1 CDS ygjQ NC_007946.1 3463137 3463838 D hypothetical protein 3463137..3463838 Escherichia coli UTI89 3990117 YP_542502.1 CDS ygjR NC_007946.1 3463899 3464903 D oxidoreductase YgjR 3463899..3464903 Escherichia coli UTI89 3990118 YP_542503.1 CDS ygjT NC_007946.1 3465186 3466151 D hypothetical protein 3465186..3466151 Escherichia coli UTI89 3990119 YP_542504.1 CDS ygjU NC_007946.1 3466475 3467719 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3466475..3467719 Escherichia coli UTI89 3990120 YP_542505.1 CDS ygjV NC_007946.1 3467723 3468274 R hypothetical protein complement(3467723..3468274) Escherichia coli UTI89 3990121 YP_542506.1 CDS uxaA NC_007946.1 3468357 3469844 R altronate hydrolase complement(3468357..3469844) Escherichia coli UTI89 3990122 YP_542507.1 CDS uxaC NC_007946.1 3469859 3471334 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3469859..3471334) Escherichia coli UTI89 3990123 YP_542508.1 CDS exuT NC_007946.1 3471634 3473052 D hexuronate transporter 3471634..3473052 Escherichia coli UTI89 3990124 YP_542509.2 CDS exuR NC_007946.1 3473182 3473958 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3473182..3473958 Escherichia coli UTI89 3990125 YP_542510.1 CDS yqjA NC_007946.1 3474303 3474965 D hypothetical protein 3474303..3474965 Escherichia coli UTI89 3990126 YP_542511.1 CDS yqjB NC_007946.1 3474969 3475352 D hypothetical protein 3474969..3475352 Escherichia coli UTI89 3990127 YP_542512.1 CDS yqjC NC_007946.1 3475484 3475867 D hypothetical protein 3475484..3475867 Escherichia coli UTI89 3990128 YP_542513.1 CDS yqjD NC_007946.1 3475905 3476210 D hypothetical protein 3475905..3476210 Escherichia coli UTI89 3990129 YP_542514.1 CDS yqjE NC_007946.1 3476213 3476617 D hypothetical protein 3476213..3476617 Escherichia coli UTI89 3990130 YP_542515.1 CDS yqjK NC_007946.1 3476607 3476906 D hypothetical protein 3476607..3476906 Escherichia coli UTI89 3990131 YP_542516.1 CDS yqjF NC_007946.1 3477081 3477485 D hypothetical protein 3477081..3477485 Escherichia coli UTI89 3990310 YP_542517.1 CDS yqjG NC_007946.1 3477555 3478541 D transferase 3477555..3478541 Escherichia coli UTI89 3990311 YP_542518.1 CDS yhaH NC_007946.1 3478803 3479192 D hypothetical protein 3478803..3479192 Escherichia coli UTI89 3990312 YP_542519.1 CDS yhaJ NC_007946.1 3479226 3480122 R transcriptional regulator YhaJ complement(3479226..3480122) Escherichia coli UTI89 3990313 YP_542520.1 CDS yhaK NC_007946.1 3480227 3480928 D hypothetical protein 3480227..3480928 Escherichia coli UTI89 3990314 YP_542521.1 CDS yhaL NC_007946.1 3480945 3481115 D hypothetical protein 3480945..3481115 Escherichia coli UTI89 3990315 YP_542522.1 CDS UTI89_C3545 NC_007946.1 3481247 3482557 R hypothetical protein complement(3481247..3482557) Escherichia coli UTI89 3990316 YP_542523.1 CDS yhaO NC_007946.1 3482585 3483916 R transport system permease complement(3482585..3483916) Escherichia coli UTI89 3990317 YP_542524.1 CDS tdcG NC_007946.1 3484191 3485561 R L-serine dehydratase 1 complement(3484191..3485561) Escherichia coli UTI89 3990318 YP_542525.1 CDS yhaR NC_007946.1 3485627 3486079 R hypothetical protein complement(3485627..3486079) Escherichia coli UTI89 3990319 YP_542526.1 CDS tdcE NC_007946.1 3486030 3488324 R keto-acid formate acetyltransferase complement(3486030..3488324) Escherichia coli UTI89 3990320 YP_542527.1 CDS tdcD NC_007946.1 3488358 3489578 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3488358..3489578) Escherichia coli UTI89 3990321 YP_542528.1 CDS tdcC NC_007946.1 3489592 3490923 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3489592..3490923) Escherichia coli UTI89 3990322 YP_542529.1 CDS tdcB NC_007946.1 3490945 3491934 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3490945..3491934) Escherichia coli UTI89 3990323 YP_542530.1 CDS tdcA NC_007946.1 3492033 3492971 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3492033..3492971) Escherichia coli UTI89 3990324 YP_542531.2 CDS tdcR NC_007946.1 3493161 3493505 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3493161..3493505 Escherichia coli UTI89 3990325 YP_542532.1 CDS yhaD NC_007946.1 3494479 3495705 R glycerate kinase I complement(3494479..3495705) Escherichia coli UTI89 3990326 YP_542533.2 CDS garR NC_007946.1 3495721 3496611 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3495721..3496611) Escherichia coli UTI89 3990327 YP_542534.1 CDS yhaF NC_007946.1 3496641 3497411 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3496641..3497411) Escherichia coli UTI89 3990328 YP_542535.1 CDS yhaU NC_007946.1 3497427 3498761 R galactarate transporter complement(3497427..3498761) Escherichia coli UTI89 3990329 YP_542536.1 CDS garD NC_007946.1 3499136 3500707 D synonym: b3128, yhaG; D-galactarate dehydratase 3499136..3500707 Escherichia coli UTI89 3992470 YP_542537.1 CDS agaR NC_007946.1 3500759 3501583 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3500759..3501583) Escherichia coli UTI89 3992471 YP_542538.1 CDS agaZ NC_007946.1 3501832 3503112 D tagatose 6-phosphate kinase 2 3501832..3503112 Escherichia coli UTI89 3992472 YP_542539.1 CDS agaV NC_007946.1 3503099 3503608 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3503099..3503608 Escherichia coli UTI89 3992473 YP_542540.1 CDS UTI89_C3563 NC_007946.1 3503619 3504398 D phosphotransferase system enzyme subunit 3503619..3504398 Escherichia coli UTI89 3992474 YP_542541.1 CDS UTI89_C3564 NC_007946.1 3504382 3505266 D PTS system N-acetylgalactosamine-specific transporter subunit IID 3504382..3505266 Escherichia coli UTI89 3992475 YP_542542.1 CDS UTI89_C3565 NC_007946.1 3505284 3505718 D phosphotransferase system enzyme subunit 3505284..3505718 Escherichia coli UTI89 3992476 YP_542543.1 CDS UTI89_C3566 NC_007946.1 3505694 3506848 D N-acetylgalctosamine-6-phosphate deacetylase 3505694..3506848 Escherichia coli UTI89 3992477 YP_542544.1 CDS agaS NC_007946.1 3507197 3508351 D tagatose-6-phosphate ketose/aldose isomerase 3507197..3508351 Escherichia coli UTI89 3992478 YP_542545.1 CDS kbaY NC_007946.1 3508364 3509224 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3508364..3509224 Escherichia coli UTI89 3992479 YP_542546.1 CDS agaB NC_007946.1 3509391 3509867 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3509391..3509867 Escherichia coli UTI89 3992480 YP_542547.1 CDS agaC NC_007946.1 3509906 3510709 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3509906..3510709 Escherichia coli UTI89 3992481 YP_542548.1 CDS agaD NC_007946.1 3510630 3511490 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3510630..3511490 Escherichia coli UTI89 3992482 YP_542549.1 CDS agaI NC_007946.1 3511491 3512258 D galactosamine-6-phosphate isomerase 3511491..3512258 Escherichia coli UTI89 3992483 YP_542550.1 CDS yraL NC_007946.1 3512308 3513171 R hypothetical protein complement(3512308..3513171) Escherichia coli UTI89 3992484 YP_542551.1 CDS yraN NC_007946.1 3515230 3515625 D hypothetical protein 3515230..3515625 Escherichia coli UTI89 3992485 YP_542552.1 CDS UTI89_C3575 NC_007946.1 3515494 3515619 R hypothetical protein complement(3515494..3515619) Escherichia coli UTI89 3992486 YP_542553.1 CDS yraO NC_007946.1 3515645 3516235 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; chromosome replication initiator DnaA 3515645..3516235 Escherichia coli UTI89 3992487 YP_542554.1 CDS yraP NC_007946.1 3516245 3516820 D hypothetical protein 3516245..3516820 Escherichia coli UTI89 3992488 YP_542555.1 CDS yraQ NC_007946.1 3516933 3517973 R hypothetical protein complement(3516933..3517973) Escherichia coli UTI89 3990631 YP_542556.1 CDS yraR NC_007946.1 3518046 3518681 R hypothetical protein complement(3518046..3518681) Escherichia coli UTI89 3990632 YP_542557.1 CDS yhbO NC_007946.1 3518767 3519327 D hypothetical protein 3518767..3519327 Escherichia coli UTI89 3990633 YP_542558.1 CDS yhbP NC_007946.1 3519307 3519750 R hypothetical protein complement(3519307..3519750) Escherichia coli UTI89 3990634 YP_542559.1 CDS yhbQ NC_007946.1 3519801 3520103 D GIY-YIG nuclease superfamily protein 3519801..3520103 Escherichia coli UTI89 3990635 YP_542560.1 CDS yhbS NC_007946.1 3520090 3520593 R acetyltransferase YhbS complement(3520090..3520593) Escherichia coli UTI89 3990636 YP_542561.1 CDS yhbT NC_007946.1 3520587 3521135 R hypothetical protein complement(3520587..3521135) Escherichia coli UTI89 3990637 YP_542562.1 CDS yhbU NC_007946.1 3521293 3522315 D protease YhbU 3521293..3522315 Escherichia coli UTI89 3990638 YP_542563.1 CDS yhbV NC_007946.1 3522306 3523202 D hypothetical protein 3522306..3523202 Escherichia coli UTI89 3990639 YP_542564.1 CDS yhbW NC_007946.1 3523283 3524290 D hypothetical protein 3523283..3524290 Escherichia coli UTI89 3990640 YP_542565.1 CDS mtr NC_007946.1 3524408 3525652 R tryptophan transporter of high affinity; tryptophan permease complement(3524408..3525652) Escherichia coli UTI89 3990641 YP_542566.1 CDS UTI89_C3589 NC_007946.1 3525668 3525805 D hypothetical protein 3525668..3525805 Escherichia coli UTI89 3990642 YP_542567.2 CDS deaD NC_007946.1 3525806 3527695 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3525806..3527695) Escherichia coli UTI89 3990643 YP_542568.1 CDS UTI89_C3591 NC_007946.1 3527832 3527990 D hypothetical protein 3527832..3527990 Escherichia coli UTI89 3990644 YP_542569.1 CDS nlpI NC_007946.1 3527875 3528759 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3527875..3528759) Escherichia coli UTI89 3990645 YP_542570.1 CDS UTI89_C3593 NC_007946.1 3528805 3531027 D hypothetical protein 3528805..3531027 Escherichia coli UTI89 3990646 YP_542571.1 CDS pnp NC_007946.1 3528868 3531090 R polynucleotide phosphorylase complement(3528868..3531090) Escherichia coli UTI89 3990647 YP_542572.1 CDS rpsO NC_007946.1 3531250 3531519 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3531250..3531519) Escherichia coli UTI89 3990648 YP_542573.1 CDS truB NC_007946.1 3531668 3532612 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3531668..3532612) Escherichia coli UTI89 3990649 YP_542574.2 CDS rbfA NC_007946.1 3532612 3533013 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3532612..3533013) Escherichia coli UTI89 3990650 YP_542575.1 CDS infB NC_007946.1 3533177 3535849 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3533177..3535849) Escherichia coli UTI89 3994745 YP_542576.1 CDS UTI89_C3599 NC_007946.1 3535706 3537175 D hypothetical protein 3535706..3537175 Escherichia coli UTI89 3994746 YP_542577.1 CDS nusA NC_007946.1 3535874 3537361 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3535874..3537361) Escherichia coli UTI89 3994747 YP_542578.1 CDS yhbC NC_007946.1 3537389 3537853 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3537389..3537853) Escherichia coli UTI89 3994748 YP_542580.1 CDS argG NC_007946.1 3538472 3539815 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3538472..3539815 Escherichia coli UTI89 3994751 YP_542581.1 CDS yhbX NC_007946.1 3539823 3541481 R outer membrane protein YhbX complement(3539823..3541481) Escherichia coli UTI89 3994752 YP_542582.2 CDS secG NC_007946.1 3542003 3542335 R preprotein translocase subunit SecG complement(3542003..3542335) Escherichia coli UTI89 3994754 YP_542583.1 CDS glmM NC_007946.1 3542563 3543900 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3542563..3543900) Escherichia coli UTI89 3994755 YP_542584.2 CDS folP NC_007946.1 3543893 3544741 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3543893..3544741) Escherichia coli UTI89 3994756 YP_542585.1 CDS hflB NC_007946.1 3544831 3546765 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3544831..3546765) Escherichia coli UTI89 3994757 YP_542586.1 CDS rrmJ NC_007946.1 3546865 3547494 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase complement(3546865..3547494) Escherichia coli UTI89 3994758 YP_542587.1 CDS UTI89_C3612 NC_007946.1 3547550 3547852 R hypothetical protein complement(3547550..3547852) Escherichia coli UTI89 3994759 YP_542588.1 CDS yhbY NC_007946.1 3547620 3547913 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3547620..3547913 Escherichia coli UTI89 3994760 YP_542589.1 CDS greA NC_007946.1 3548069 3548545 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3548069..3548545) Escherichia coli UTI89 3994761 YP_542590.1 CDS dacB NC_007946.1 3548793 3550226 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3548793..3550226 Escherichia coli UTI89 3994096 YP_542591.1 CDS obgE NC_007946.1 3550267 3551427 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3550267..3551427) Escherichia coli UTI89 3994097 YP_542592.1 CDS yhbE NC_007946.1 3551443 3552408 R transport protein YhbE complement(3551443..3552408) Escherichia coli UTI89 3994098 YP_542593.1 CDS rpmA NC_007946.1 3552535 3552792 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3552535..3552792) Escherichia coli UTI89 3994099 YP_542594.1 CDS UTI89_C3619 NC_007946.1 3552786 3553331 D hypothetical protein 3552786..3553331 Escherichia coli UTI89 3994100 YP_542595.1 CDS rplU NC_007946.1 3552813 3553124 R 50S ribosomal protein L21 complement(3552813..3553124) Escherichia coli UTI89 3994101 YP_542596.1 CDS ispB NC_007946.1 3553383 3554354 D octaprenyl diphosphate synthase 3553383..3554354 Escherichia coli UTI89 3994102 YP_542597.1 CDS nlp NC_007946.1 3554587 3554865 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3554587..3554865 Escherichia coli UTI89 3994103 YP_542598.1 CDS murA NC_007946.1 3554913 3556172 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3554913..3556172) Escherichia coli UTI89 3994104 YP_542599.1 CDS yrbA NC_007946.1 3556227 3556496 R hypothetical protein complement(3556227..3556496) Escherichia coli UTI89 3994105 YP_542600.1 CDS UTI89_C3625 NC_007946.1 3556293 3556634 D hypothetical protein 3556293..3556634 Escherichia coli UTI89 3994106 YP_542601.1 CDS yrbB NC_007946.1 3556641 3557030 R hypothetical protein complement(3556641..3557030) Escherichia coli UTI89 3994107 YP_542602.1 CDS UTI89_C3627 NC_007946.1 3556922 3557557 D hypothetical protein 3556922..3557557 Escherichia coli UTI89 3994108 YP_542603.1 CDS yrbC NC_007946.1 3556934 3557569 R hypothetical protein complement(3556934..3557569) Escherichia coli UTI89 3994109 YP_542604.1 CDS yrbD NC_007946.1 3557588 3558154 R hypothetical protein complement(3557588..3558154) Escherichia coli UTI89 3994110 YP_542605.1 CDS yrbE NC_007946.1 3558144 3558926 R hypothetical protein complement(3558144..3558926) Escherichia coli UTI89 3994111 YP_542606.1 CDS yrbF NC_007946.1 3558934 3559743 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF complement(3558934..3559743) Escherichia coli UTI89 3994112 YP_542607.1 CDS yrbG NC_007946.1 3559953 3560930 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3559953..3560930 Escherichia coli UTI89 3994113 YP_542608.1 CDS yrbH NC_007946.1 3560923 3561930 D D-arabinose 5-phosphate isomerase 3560923..3561930 Escherichia coli UTI89 3994114 YP_542609.1 CDS yrbI NC_007946.1 3561951 3562517 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3561951..3562517 Escherichia coli UTI89 3994115 YP_542610.1 CDS yrbK NC_007946.1 3562514 3563089 D hypothetical protein 3562514..3563089 Escherichia coli UTI89 3993793 YP_542611.1 CDS yhbN NC_007946.1 3563037 3563615 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3563037..3563615 Escherichia coli UTI89 3993794 YP_542612.1 CDS yhbG NC_007946.1 3563622 3564347 D ABC transporter ATP-binding protein YhbG 3563622..3564347 Escherichia coli UTI89 3993795 YP_542613.1 CDS rpoN NC_007946.1 3564395 3565828 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3564395..3565828 Escherichia coli UTI89 3993796 YP_542614.1 CDS yhbH NC_007946.1 3565851 3566138 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3565851..3566138 Escherichia coli UTI89 3993797 YP_542615.1 CDS ptsN NC_007946.1 3566232 3566747 D PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3566232..3566747 Escherichia coli UTI89 3993798 YP_542616.1 CDS yhbJ NC_007946.1 3566793 3567647 D hypothetical protein 3566793..3567647 Escherichia coli UTI89 3993799 YP_542617.1 CDS ptsO NC_007946.1 3567644 3567916 D phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3567644..3567916 Escherichia coli UTI89 3993800 YP_542618.1 CDS yrbL NC_007946.1 3568130 3568762 D hypothetical protein 3568130..3568762 Escherichia coli UTI89 3993801 YP_542619.1 CDS mtgA NC_007946.1 3568759 3569487 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3568759..3569487) Escherichia coli UTI89 3993802 YP_542620.1 CDS yhbL NC_007946.1 3569484 3570137 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(3569484..3570137) Escherichia coli UTI89 3993803 YP_542621.1 CDS arcB NC_007946.1 3570367 3572703 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3570367..3572703) Escherichia coli UTI89 3993804 YP_542622.1 CDS yhcC NC_007946.1 3572799 3573665 R hypothetical protein complement(3572799..3573665) Escherichia coli UTI89 3993805 YP_542623.1 CDS UTI89_C3648 NC_007946.1 3573993 3574130 R hypothetical protein complement(3573993..3574130) Escherichia coli UTI89 3993806 YP_542624.2 CDS gltB NC_007946.1 3574310 3578863 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3574310..3578863 Escherichia coli UTI89 3993807 YP_542625.1 CDS gltD NC_007946.1 3578876 3580294 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3578876..3580294 Escherichia coli UTI89 3993808 YP_542626.1 CDS yhcH NC_007946.1 3580362 3580826 R hypothetical protein complement(3580362..3580826) Escherichia coli UTI89 3993809 YP_542627.1 CDS UTI89_C3652 NC_007946.1 3580823 3581731 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3580823..3581731) Escherichia coli UTI89 3993810 YP_542628.1 CDS yhcJ NC_007946.1 3581695 3582426 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3581695..3582426) Escherichia coli UTI89 3993811 YP_542629.1 CDS nanT NC_007946.1 3582432 3583952 R sialic acid transporter complement(3582432..3583952) Escherichia coli UTI89 3991279 YP_542630.1 CDS nanA NC_007946.1 3584031 3584924 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3584031..3584924) Escherichia coli UTI89 3991280 YP_542631.1 CDS nanR NC_007946.1 3585046 3585837 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3585046..3585837) Escherichia coli UTI89 3991281 YP_542632.1 CDS sspB NC_007946.1 3585945 3586442 R ClpXP protease specificity-enhancing factor complement(3585945..3586442) Escherichia coli UTI89 3991282 YP_542633.1 CDS sspA NC_007946.1 3586448 3587086 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3586448..3587086) Escherichia coli UTI89 3991283 YP_542634.1 CDS UTI89_C3659 NC_007946.1 3587028 3587237 D hypothetical protein 3587028..3587237 Escherichia coli UTI89 3991284 YP_542635.1 CDS rpsI NC_007946.1 3587481 3587873 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3587481..3587873) Escherichia coli UTI89 3991285 YP_542636.2 CDS rplM NC_007946.1 3587889 3588317 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3587889..3588317) Escherichia coli UTI89 3991286 YP_542637.1 CDS yhcM NC_007946.1 3588537 3589664 R hypothetical protein complement(3588537..3589664) Escherichia coli UTI89 3991287 YP_542638.1 CDS yhcB NC_007946.1 3589858 3590256 D cytochrome d ubiquinol oxidase subunit III 3589858..3590256 Escherichia coli UTI89 3991288 YP_542639.1 CDS UTI89_C3664 NC_007946.1 3589904 3590317 D hypothetical protein 3589904..3590317 Escherichia coli UTI89 3991289 YP_542640.1 CDS degQ NC_007946.1 3590368 3591777 D synonym: b3234, hhoA, EG12612; serine endoprotease 3590368..3591777 Escherichia coli UTI89 3991290 YP_542641.1 CDS degS NC_007946.1 3591867 3592934 D synonym: b3235, hhoB, htrH; serine endoprotease 3591867..3592934 Escherichia coli UTI89 3991291 YP_542642.1 CDS mdh NC_007946.1 3592997 3594001 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3592997..3594001) Escherichia coli UTI89 3991292 YP_542643.1 CDS argR NC_007946.1 3594370 3594840 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3594370..3594840 Escherichia coli UTI89 3991293 YP_542644.1 CDS yhcN NC_007946.1 3595153 3595467 D hypothetical protein 3595153..3595467 Escherichia coli UTI89 3991294 YP_542645.1 CDS yhcO NC_007946.1 3595522 3595794 R hypothetical protein complement(3595522..3595794) Escherichia coli UTI89 3991295 YP_542646.1 CDS UTI89_C3671 NC_007946.1 3595886 3597853 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3595886..3597853) Escherichia coli UTI89 3991296 YP_542647.1 CDS yhcQ NC_007946.1 3597859 3598791 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3597859..3598791) Escherichia coli UTI89 3991297 YP_542648.2 CDS yhcR NC_007946.1 3598799 3599002 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3598799..3599002) Escherichia coli UTI89 3991298 YP_542649.1 CDS yhcS NC_007946.1 3599185 3600114 D DNA-binding transcriptional regulator 3599185..3600114 Escherichia coli UTI89 3990230 YP_542650.1 CDS tldD NC_007946.1 3600242 3601687 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3600242..3601687) Escherichia coli UTI89 3990231 YP_542651.1 CDS yhdP NC_007946.1 3601843 3605643 R hypothetical protein complement(3601843..3605643) Escherichia coli UTI89 3990232 YP_542652.2 CDS rng NC_007946.1 3605711 3607180 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3605711..3607180) Escherichia coli UTI89 3990233 YP_542653.1 CDS yhdE NC_007946.1 3607170 3607763 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3607170..3607763) Escherichia coli UTI89 3990234 YP_542654.1 CDS mreD NC_007946.1 3607772 3608260 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3607772..3608260) Escherichia coli UTI89 3990235 YP_542655.1 CDS mreC NC_007946.1 3608260 3609363 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3608260..3609363) Escherichia coli UTI89 3990236 YP_542656.1 CDS mreB NC_007946.1 3609429 3610547 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3609429..3610547) Escherichia coli UTI89 3990237 YP_542657.1 CDS UTI89_C3682 NC_007946.1 3610580 3610768 D hypothetical protein 3610580..3610768 Escherichia coli UTI89 3990238 YP_542658.1 CDS yhdA NC_007946.1 3610777 3612717 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3610777..3612717) Escherichia coli UTI89 3990239 YP_542659.1 CDS yhdH NC_007946.1 3612869 3613843 D protein YhdH 3612869..3613843 Escherichia coli UTI89 3990240 YP_542660.1 CDS UTI89_C3685 NC_007946.1 3613880 3614044 D hypothetical protein 3613880..3614044 Escherichia coli UTI89 3990241 YP_542661.1 CDS UTI89_C3686 NC_007946.1 3613901 3614002 R hypothetical protein complement(3613901..3614002) Escherichia coli UTI89 3990242 YP_542662.1 CDS UTI89_C3687 NC_007946.1 3614660 3614848 D orf 5' of BCCP; hypothetical protein 3614660..3614848 Escherichia coli UTI89 3990243 YP_542663.1 CDS accB NC_007946.1 3614821 3615291 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3614821..3615291 Escherichia coli UTI89 3990244 YP_542664.2 CDS accC NC_007946.1 3615302 3616651 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3615302..3616651 Escherichia coli UTI89 3990245 YP_542665.1 CDS UTI89_C3690 NC_007946.1 3616743 3617789 R hypothetical protein complement(3616743..3617789) Escherichia coli UTI89 3990246 YP_542666.1 CDS UTI89_C3691 NC_007946.1 3617786 3618748 R hypothetical protein complement(3617786..3618748) Escherichia coli UTI89 3990247 YP_542667.1 CDS rbsC NC_007946.1 3618770 3619759 R synonym: b3750, rbsA, rbsP, rbsT; ribose transport system permease RbsC complement(3618770..3619759) Escherichia coli UTI89 3990248 YP_542668.1 CDS UTI89_C3693 NC_007946.1 3619760 3621289 R synonym: rbsT, rbsP, b3749, prlB; ribose transport ATP-binding protein RbsA complement(3619760..3621289) Escherichia coli UTI89 3992776 YP_542669.1 CDS UTI89_C3694 NC_007946.1 3621320 3622216 R ribose ABC transporter complement(3621320..3622216) Escherichia coli UTI89 3992777 YP_542670.1 CDS gatY NC_007946.1 3622246 3623100 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(3622246..3623100) Escherichia coli UTI89 3992778 YP_542671.1 CDS UTI89_C3696 NC_007946.1 3623075 3623203 D hypothetical protein 3623075..3623203 Escherichia coli UTI89 3992779 YP_542672.1 CDS UTI89_C3697 NC_007946.1 3623441 3624271 D hypothetical protein 3623441..3624271 Escherichia coli UTI89 3992780 YP_542673.1 CDS UTI89_C3698 NC_007946.1 3624228 3625238 D hypothetical protein 3624228..3625238 Escherichia coli UTI89 3992781 YP_542674.1 CDS yhdT NC_007946.1 3625313 3625573 D hypothetical protein 3625313..3625573 Escherichia coli UTI89 3992782 YP_542675.1 CDS panF NC_007946.1 3625557 3627014 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3625557..3627014 Escherichia coli UTI89 3992783 YP_542676.1 CDS prmA NC_007946.1 3627026 3627907 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3627026..3627907 Escherichia coli UTI89 3992784 YP_542677.1 CDS yhdG NC_007946.1 3628236 3629201 D tRNA-dihydrouridine synthase B 3628236..3629201 Escherichia coli UTI89 3992785 YP_542678.1 CDS fis NC_007946.1 3629227 3629523 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; Fis family transcriptional regulator 3629227..3629523 Escherichia coli UTI89 3992786 YP_542679.2 CDS yhdJ NC_007946.1 3629611 3630495 D methyltransferase 3629611..3630495 Escherichia coli UTI89 3992787 YP_542680.1 CDS yhdU NC_007946.1 3630552 3630758 D hypothetical protein 3630552..3630758 Escherichia coli UTI89 3992788 YP_542681.1 CDS envR NC_007946.1 3630761 3631423 R DNA-binding transcriptional regulator EnvR complement(3630761..3631423) Escherichia coli UTI89 3992789 YP_542682.1 CDS acrE NC_007946.1 3631822 3632979 D acriflavine resistance protein E 3631822..3632979 Escherichia coli UTI89 3992790 YP_542683.1 CDS acrF NC_007946.1 3632991 3636095 D acriflavine resistance protein F 3632991..3636095 Escherichia coli UTI89 3992791 YP_542684.1 CDS yhdV NC_007946.1 3636348 3636569 D hypothetical protein 3636348..3636569 Escherichia coli UTI89 3992792 YP_542685.1 CDS yhdW NC_007946.1 3637000 3638025 D periplasmic amino-acid ABC transporter binding protein 3637000..3638025 Escherichia coli UTI89 3992793 YP_542686.1 CDS yhdX NC_007946.1 3638075 3639274 D amino acid ABC transporter permease 3638075..3639274 Escherichia coli UTI89 3992794 YP_542687.1 CDS yhdY NC_007946.1 3639281 3640387 D transport system permease 3639281..3640387 Escherichia coli UTI89 3992795 YP_542688.1 CDS yhdZ NC_007946.1 3640395 3641153 D amino acid ABC transporter ATP-binding protein 3640395..3641153 Escherichia coli UTI89 3991338 YP_542692.1 CDS yrdA NC_007946.1 3646821 3647591 D protein YrdA 3646821..3647591 Escherichia coli UTI89 3991349 YP_542693.1 CDS yrdB NC_007946.1 3647567 3647824 R hypothetical protein complement(3647567..3647824) Escherichia coli UTI89 3990037 YP_542694.1 CDS aroE NC_007946.1 3647821 3648639 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3647821..3648639) Escherichia coli UTI89 3990038 YP_542695.1 CDS yrdC NC_007946.1 3648644 3649261 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3648644..3649261) Escherichia coli UTI89 3990039 YP_542696.1 CDS yrdD NC_007946.1 3649221 3649763 R hypothetical protein complement(3649221..3649763) Escherichia coli UTI89 3990040 YP_542697.1 CDS smg NC_007946.1 3649792 3650265 R hypothetical protein complement(3649792..3650265) Escherichia coli UTI89 3990041 YP_542698.1 CDS smf NC_007946.1 3650237 3651361 R DNA protecting protein DprA complement(3650237..3651361) Escherichia coli UTI89 3990042 YP_542699.1 CDS def NC_007946.1 3651491 3652000 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3651491..3652000 Escherichia coli UTI89 3990043 YP_542700.1 CDS fmt NC_007946.1 3652015 3652962 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3652015..3652962 Escherichia coli UTI89 3990044 YP_542701.1 CDS sun NC_007946.1 3653014 3654303 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3653014..3654303 Escherichia coli UTI89 3990045 YP_542702.1 CDS trkA NC_007946.1 3654325 3655701 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 3654325..3655701 Escherichia coli UTI89 3990046 YP_542703.1 CDS mscL NC_007946.1 3655831 3656244 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3655831..3656244 Escherichia coli UTI89 3990047 YP_542704.1 CDS yhdL NC_007946.1 3656241 3656459 R regulator complement(3656241..3656459) Escherichia coli UTI89 3990048 YP_542705.1 CDS zntR NC_007946.1 3656515 3656940 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3656515..3656940) Escherichia coli UTI89 3990049 YP_542706.1 CDS yhdN NC_007946.1 3656951 3657319 R hypothetical protein complement(3656951..3657319) Escherichia coli UTI89 3990050 YP_542707.1 CDS rplQ NC_007946.1 3657426 3657809 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3657426..3657809) Escherichia coli UTI89 3990051 YP_542708.1 CDS rpoA NC_007946.1 3657850 3658839 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3657850..3658839) Escherichia coli UTI89 3990052 YP_542709.1 CDS rpsD NC_007946.1 3658865 3659485 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3658865..3659485) Escherichia coli UTI89 3990053 YP_542710.1 CDS rpsK NC_007946.1 3659519 3659908 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3659519..3659908) Escherichia coli UTI89 3990054 YP_542712.1 CDS rpsM NC_007946.1 3659925 3660281 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3659925..3660281) Escherichia coli UTI89 3990056 YP_542713.1 CDS rpmJ NC_007946.1 3660428 3660544 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3660428..3660544) Escherichia coli UTI89 3991222 YP_542714.1 CDS secY NC_007946.1 3660576 3661907 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3660576..3661907) Escherichia coli UTI89 3991223 YP_542715.1 CDS rplO NC_007946.1 3661915 3662349 R late assembly protein; 50S ribosomal protein L15 complement(3661915..3662349) Escherichia coli UTI89 3991224 YP_542716.1 CDS rpmD NC_007946.1 3662353 3662532 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3662353..3662532) Escherichia coli UTI89 3991225 YP_542717.1 CDS UTI89_C3749 NC_007946.1 3662506 3663057 D hypothetical protein 3662506..3663057 Escherichia coli UTI89 3991226 YP_542718.1 CDS rpsE NC_007946.1 3662536 3663039 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3662536..3663039) Escherichia coli UTI89 3991227 YP_542719.1 CDS rplR NC_007946.1 3663054 3663407 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3663054..3663407) Escherichia coli UTI89 3991228 YP_542720.1 CDS UTI89_C3752 NC_007946.1 3663108 3663731 D hypothetical protein 3663108..3663731 Escherichia coli UTI89 3991229 YP_542721.1 CDS rplF NC_007946.1 3663417 3663950 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3663417..3663950) Escherichia coli UTI89 3991230 YP_542722.1 CDS UTI89_C3754 NC_007946.1 3663816 3664373 D hypothetical protein 3663816..3664373 Escherichia coli UTI89 3991231 YP_542723.1 CDS rpsH NC_007946.1 3663963 3664355 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3663963..3664355) Escherichia coli UTI89 3991232 YP_542724.1 CDS rpsN NC_007946.1 3664389 3664694 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3664389..3664694) Escherichia coli UTI89 3991233 YP_542725.1 CDS rplE NC_007946.1 3664709 3665248 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3664709..3665248) Escherichia coli UTI89 3991234 YP_542726.1 CDS rplX NC_007946.1 3665263 3665577 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3665263..3665577) Escherichia coli UTI89 3991235 YP_542727.1 CDS UTI89_C3759 NC_007946.1 3665459 3666013 D hypothetical protein 3665459..3666013 Escherichia coli UTI89 3991236 YP_542728.1 CDS rplN NC_007946.1 3665588 3665959 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3665588..3665959) Escherichia coli UTI89 3991237 YP_542729.1 CDS rpsQ NC_007946.1 3666124 3666378 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3666124..3666378) Escherichia coli UTI89 3991238 YP_542730.1 CDS rpmC NC_007946.1 3666378 3666569 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3666378..3666569) Escherichia coli UTI89 3991239 YP_542732.1 CDS rplP NC_007946.1 3666569 3666979 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3666569..3666979) Escherichia coli UTI89 3994686 YP_542733.1 CDS rpsC NC_007946.1 3666992 3667693 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3666992..3667693) Escherichia coli UTI89 3994687 YP_542735.1 CDS rplV NC_007946.1 3667711 3668043 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3667711..3668043) Escherichia coli UTI89 3994689 YP_542736.1 CDS rpsS NC_007946.1 3668058 3668336 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3668058..3668336) Escherichia coli UTI89 3994690 YP_542737.1 CDS UTI89_C3769 NC_007946.1 3668320 3669246 D hypothetical protein 3668320..3669246 Escherichia coli UTI89 3994691 YP_542738.1 CDS rplB NC_007946.1 3668353 3669174 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3668353..3669174) Escherichia coli UTI89 3994692 YP_542739.1 CDS rplW NC_007946.1 3669192 3669494 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3669192..3669494) Escherichia coli UTI89 3994693 YP_542741.1 CDS rplD NC_007946.1 3669491 3670096 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3669491..3670096) Escherichia coli UTI89 3994695 YP_542742.1 CDS UTI89_C3774 NC_007946.1 3670026 3670727 D hypothetical protein 3670026..3670727 Escherichia coli UTI89 3994696 YP_542743.1 CDS rplC NC_007946.1 3670107 3670736 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3670107..3670736) Escherichia coli UTI89 3994697 YP_542744.1 CDS rpsJ NC_007946.1 3670769 3671080 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3670769..3671080) Escherichia coli UTI89 3994698 YP_542745.1 CDS pinO NC_007946.1 3671318 3671737 R calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO complement(3671318..3671737) Escherichia coli UTI89 3994699 YP_542746.1 CDS yheD NC_007946.1 3671739 3673208 R synonym: b3323, yheD, EG12888; general secretion pathway protein A complement(3671739..3673208) Escherichia coli UTI89 3994700 YP_542747.1 CDS yheE NC_007946.1 3673388 3674203 D synonym: b3324, yheE, EG12889; general secretion pathway protein C 3673388..3674203 Escherichia coli UTI89 3994701 YP_542748.1 CDS yheF NC_007946.1 3674175 3676139 D synonym: b3325, yheF, EG12890; general secretion pathway protein D 3674175..3676139 Escherichia coli UTI89 3994702 YP_542749.1 CDS yheG NC_007946.1 3676149 3677630 D synonym: b3326, yheG, EG12891; general secretion pathway protein E 3676149..3677630 Escherichia coli UTI89 3994703 YP_542750.1 CDS hofF NC_007946.1 3677627 3678823 D synonym: b3327, hofF, hopF, EG12885; general secretion pathway protein F 3677627..3678823 Escherichia coli UTI89 3994704 YP_542751.1 CDS hofG NC_007946.1 3678833 3679270 D synonym: b3328, hofG, hopG, hopg, EG12886; general secretion pathway protein G 3678833..3679270 Escherichia coli UTI89 3994705 YP_542752.1 CDS hofH NC_007946.1 3679278 3679787 D synonym: b3329, hofH, hopH, EG12887; general secretion pathway protein H 3679278..3679787 Escherichia coli UTI89 3993447 YP_542753.1 CDS yheH NC_007946.1 3679745 3680179 D synonym: b3330, yheH, yheh, EG12892; general secretion pathway protein I 3679745..3680179 Escherichia coli UTI89 3993448 YP_542754.1 CDS yheI NC_007946.1 3680172 3680759 D synonym: b3331, yheI, yhei, EG12893; general secretion pathway protein J 3680172..3680759 Escherichia coli UTI89 3993449 YP_542755.1 CDS yheJ NC_007946.1 3680752 3681735 D synonym: b3332, yheJ, yhej, EG12894; general secretion pathway protein K 3680752..3681735 Escherichia coli UTI89 3993450 YP_542756.1 CDS yheK NC_007946.1 3681747 3682913 D synonym: b3333, yheK, yheL, yhek, EG12895; general secretion pathway protein L 3681747..3682913 Escherichia coli UTI89 3993451 YP_542757.1 CDS pshM NC_007946.1 3682886 3683371 D synonym: b3334, hopZ, pshM; general secretion pathway protein M 3682886..3683371 Escherichia coli UTI89 3993452 YP_542758.1 CDS hofD NC_007946.1 3683371 3684048 D synonym: b3335, hofD, hopD, hopO, yheC; type 4 prepilin-like proteins leader peptide processing enzyme 3683371..3684048 Escherichia coli UTI89 3993453 YP_542759.1 CDS bfr NC_007946.1 3684077 3684553 R iron storage protein; bacterioferritin complement(3684077..3684553) Escherichia coli UTI89 3993454 YP_542760.1 CDS bfd NC_007946.1 3684625 3684819 R synonym: b3337, yheA, gen-64; bacterioferritin-associated ferredoxin complement(3684625..3684819) Escherichia coli UTI89 3993455 YP_542761.1 CDS yheB NC_007946.1 3684988 3687690 R bifunctional chitinase/lysozyme complement(3684988..3687690) Escherichia coli UTI89 3993456 YP_542762.1 CDS UTI89_C3794 NC_007946.1 3687775 3687933 R hypothetical protein complement(3687775..3687933) Escherichia coli UTI89 3993457 YP_542763.1 CDS tufB NC_007946.1 3687982 3689166 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3687982..3689166) Escherichia coli UTI89 3993458 YP_542764.1 CDS UTI89_C3800 NC_007946.1 3689742 3689897 D hypothetical protein 3689742..3689897 Escherichia coli UTI89 3990846 YP_542765.1 CDS UTI89_C3801 NC_007946.1 3689866 3690027 D hypothetical protein 3689866..3690027 Escherichia coli UTI89 3990847 YP_542766.1 CDS coaA NC_007946.1 3690063 3691034 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3690063..3691034 Escherichia coli UTI89 3990848 YP_542767.1 CDS birA NC_007946.1 3691063 3692028 R BirA bifunctional protein; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(3691063..3692028) Escherichia coli UTI89 3990849 YP_542768.1 CDS murB NC_007946.1 3692025 3693053 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(3692025..3693053) Escherichia coli UTI89 3990850 YP_542773.1 CDS UTI89_C3813 NC_007946.1 3698578 3698700 R hypothetical protein complement(3698578..3698700) Escherichia coli UTI89 3990859 YP_542774.1 CDS purH NC_007946.1 3698818 3700407 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3698818..3700407 Escherichia coli UTI89 3990860 YP_542775.1 CDS purD NC_007946.1 3700419 3701708 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3700419..3701708 Escherichia coli UTI89 3990788 YP_542776.1 CDS zraS NC_007946.1 3703026 3704402 R synonym: b4003, hydH; sensor protein ZraS complement(3703026..3704402) Escherichia coli UTI89 3990789 YP_542777.2 CDS zraP NC_007946.1 3704640 3705059 D synonym: b4002, yjaI, zra; zinc resistance protein 3704640..3705059 Escherichia coli UTI89 3990790 YP_542778.1 CDS yjaH NC_007946.1 3705061 3705762 R hypothetical protein complement(3705061..3705762) Escherichia coli UTI89 3990791 YP_542779.1 CDS hupA NC_007946.1 3705769 3706041 R histone-like DNA-binding protein; transcriptional regulator HU subunit alpha complement(3705769..3706041) Escherichia coli UTI89 3990792 YP_542780.1 CDS yjaG NC_007946.1 3706228 3706818 R hypothetical protein complement(3706228..3706818) Escherichia coli UTI89 3990793 YP_542781.1 CDS nfi NC_007946.1 3706861 3707532 R Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V complement(3706861..3707532) Escherichia coli UTI89 3990794 YP_542782.1 CDS hemE NC_007946.1 3707542 3708606 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(3707542..3708606) Escherichia coli UTI89 3990795 YP_542783.1 CDS nudC NC_007946.1 3708646 3709419 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(3708646..3709419) Escherichia coli UTI89 3990796 YP_542784.1 CDS yjaE NC_007946.1 3709514 3709990 D binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 3709514..3709990 Escherichia coli UTI89 3990797 YP_542785.1 CDS thiC NC_007946.1 3710211 3712118 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3710211..3712118 Escherichia coli UTI89 3990798 YP_542786.1 CDS thiE NC_007946.1 3712115 3712753 D catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 3712115..3712753 Escherichia coli UTI89 3990799 YP_542787.1 CDS thiF NC_007946.1 3712731 3713501 D adenylyltransferase 3712731..3713501 Escherichia coli UTI89 3990800 YP_542788.1 CDS UTI89_C3828 NC_007946.1 3713485 3713685 D with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 3713485..3713685 Escherichia coli UTI89 3990801 YP_542789.2 CDS thiG NC_007946.1 3713687 3714457 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 3713687..3714457 Escherichia coli UTI89 3990802 YP_542790.1 CDS thiH NC_007946.1 3714454 3715587 D in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 3714454..3715587 Escherichia coli UTI89 3990803 YP_542791.1 CDS rpoC NC_007946.1 3715827 3720050 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(3715827..3720050) Escherichia coli UTI89 3990804 YP_542792.1 CDS rpoB NC_007946.1 3720127 3724188 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(3720127..3724188) Escherichia coli UTI89 3990805 YP_542793.1 CDS UTI89_C3833 NC_007946.1 3724349 3724855 D hypothetical protein 3724349..3724855 Escherichia coli UTI89 3990806 YP_542794.1 CDS rplL NC_007946.1 3724475 3724840 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(3724475..3724840) Escherichia coli UTI89 3993272 YP_542795.1 CDS rplJ NC_007946.1 3724907 3725404 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(3724907..3725404) Escherichia coli UTI89 3993273 YP_542796.1 CDS rplA NC_007946.1 3725696 3726400 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(3725696..3726400) Escherichia coli UTI89 3993274 YP_542797.1 CDS UTI89_C3837 NC_007946.1 3725885 3726886 D hypothetical protein 3725885..3726886 Escherichia coli UTI89 3993275 YP_542798.1 CDS rplK NC_007946.1 3726404 3726832 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(3726404..3726832) Escherichia coli UTI89 3993276 YP_542799.1 CDS nusG NC_007946.1 3726991 3727536 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(3726991..3727536) Escherichia coli UTI89 3993277 YP_542800.1 CDS secE NC_007946.1 3727538 3727921 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(3727538..3727921) Escherichia coli UTI89 3993278 YP_542801.2 CDS tufA NC_007946.1 3728151 3729335 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3728151..3729335) Escherichia coli UTI89 3993279 YP_542802.1 CDS fusA NC_007946.1 3729406 3731520 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3729406..3731520) Escherichia coli UTI89 3993280 YP_542803.1 CDS rpsG NC_007946.1 3731617 3732087 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3731617..3732087) Escherichia coli UTI89 3993281 YP_542804.2 CDS rpsL NC_007946.1 3732184 3732558 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3732184..3732558) Escherichia coli UTI89 3993282 YP_542805.1 CDS yheL NC_007946.1 3732684 3732971 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3732684..3732971) Escherichia coli UTI89 3993283 YP_542806.1 CDS yheM NC_007946.1 3732978 3733337 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3732978..3733337) Escherichia coli UTI89 3993284 YP_542807.1 CDS yheN NC_007946.1 3733337 3733723 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3733337..3733723) Escherichia coli UTI89 3993285 YP_542808.1 CDS yheO NC_007946.1 3733723 3734457 R hypothetical protein complement(3733723..3734457) Escherichia coli UTI89 3993286 YP_542809.1 CDS fkpA NC_007946.1 3734612 3735424 R rotamase; FKBP-type peptidylprolyl isomerase complement(3734612..3735424) Escherichia coli UTI89 3993287 YP_542810.1 CDS slyX NC_007946.1 3735645 3735863 D hypothetical protein 3735645..3735863 Escherichia coli UTI89 3993288 YP_542811.1 CDS slyD NC_007946.1 3735912 3736502 R rotamase; FKBP-type peptidylprolyl isomerase complement(3735912..3736502) Escherichia coli UTI89 3993289 YP_542812.1 CDS yheV NC_007946.1 3736597 3736797 R hypothetical protein complement(3736597..3736797) Escherichia coli UTI89 3993290 YP_542813.1 CDS kefB NC_007946.1 3736807 3738612 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3736807..3738612) Escherichia coli UTI89 3993291 YP_542814.1 CDS yheR NC_007946.1 3738612 3739166 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3738612..3739166) Escherichia coli UTI89 3993428 YP_542815.1 CDS yheS NC_007946.1 3739294 3741207 D ABC transporter ATP-binding protein 3739294..3741207 Escherichia coli UTI89 3993429 YP_542816.1 CDS yheT NC_007946.1 3741207 3742229 D hydrolase 3741207..3742229 Escherichia coli UTI89 3993430 YP_542817.1 CDS yheU NC_007946.1 3742223 3742441 D hypothetical protein 3742223..3742441 Escherichia coli UTI89 3993431 YP_542818.1 CDS prkB NC_007946.1 3742495 3743364 D synonym: b3355, yhfF; phosphoribulokinase 3742495..3743364 Escherichia coli UTI89 3993432 YP_542819.1 CDS yhfA NC_007946.1 3743419 3743823 R hypothetical protein complement(3743419..3743823) Escherichia coli UTI89 3993433 YP_542820.1 CDS crp NC_007946.1 3744125 3744757 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3744125..3744757 Escherichia coli UTI89 3993434 YP_542821.1 CDS yhfK NC_007946.1 3744796 3746898 D hypothetical protein 3744796..3746898 Escherichia coli UTI89 3993435 YP_542822.1 CDS argD NC_007946.1 3746965 3748185 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase complement(3746965..3748185) Escherichia coli UTI89 3993436 YP_542823.1 CDS pabA NC_007946.1 3748271 3748834 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3748271..3748834) Escherichia coli UTI89 3993437 YP_542824.1 CDS fic NC_007946.1 3748866 3749468 R cell filamentation protein Fic complement(3748866..3749468) Escherichia coli UTI89 3993438 YP_542825.1 CDS yhfG NC_007946.1 3749458 3749625 R hypothetical protein complement(3749458..3749625) Escherichia coli UTI89 3993439 YP_542826.1 CDS ppiA NC_007946.1 3749730 3750302 R peptidyl-prolyl cis-trans isomerase A complement(3749730..3750302) Escherichia coli UTI89 3993440 YP_542827.1 CDS yhfC NC_007946.1 3750572 3751753 D hypothetical protein 3750572..3751753 Escherichia coli UTI89 3993441 YP_542828.1 CDS UTI89_C3868 NC_007946.1 3751886 3752062 R hypothetical protein complement(3751886..3752062) Escherichia coli UTI89 3993442 YP_542829.1 CDS nirB NC_007946.1 3752015 3754558 D nitrite reductase [NAD(P)H] large subunit 3752015..3754558 Escherichia coli UTI89 3993443 YP_542830.1 CDS nirD NC_007946.1 3754555 3754881 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3754555..3754881 Escherichia coli UTI89 3993444 YP_542831.1 CDS nirC NC_007946.1 3755007 3755813 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3755007..3755813 Escherichia coli UTI89 3993445 YP_542832.1 CDS cysG NC_007946.1 3755832 3757205 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3755832..3757205 Escherichia coli UTI89 3993446 YP_542833.1 CDS yhfL NC_007946.1 3757457 3757624 D hypothetical protein 3757457..3757624 Escherichia coli UTI89 3993639 YP_542834.1 CDS yhfS NC_007946.1 3757732 3758817 R hypothetical protein complement(3757732..3758817) Escherichia coli UTI89 3993640 YP_542835.1 CDS yhfT NC_007946.1 3758829 3760133 R hypothetical protein complement(3758829..3760133) Escherichia coli UTI89 3993641 YP_542836.1 CDS yhfU NC_007946.1 3760145 3760537 R hypothetical protein complement(3760145..3760537) Escherichia coli UTI89 3993642 YP_542837.1 CDS yhfV NC_007946.1 3760509 3761387 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3760509..3761387) Escherichia coli UTI89 3993643 YP_542838.1 CDS yhfW NC_007946.1 3761384 3762610 R mutase complement(3761384..3762610) Escherichia coli UTI89 3993644 YP_542839.1 CDS yhfX NC_007946.1 3762611 3763774 R hypothetical protein complement(3762611..3763774) Escherichia coli UTI89 3993645 YP_542840.1 CDS yhfY NC_007946.1 3763858 3764262 R hypothetical protein complement(3763858..3764262) Escherichia coli UTI89 3993646 YP_542841.1 CDS yhfZ NC_007946.1 3764237 3765142 R hypothetical protein complement(3764237..3765142) Escherichia coli UTI89 3993647 YP_542842.1 CDS trpS NC_007946.1 3765302 3766306 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3765302..3766306) Escherichia coli UTI89 3993648 YP_542843.1 CDS gph NC_007946.1 3766299 3767057 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3766299..3767057) Escherichia coli UTI89 3993649 YP_542844.1 CDS rpe NC_007946.1 3767050 3767727 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3767050..3767727) Escherichia coli UTI89 3993650 YP_542845.1 CDS dam NC_007946.1 3767745 3768581 R DNA adenine methylase complement(3767745..3768581) Escherichia coli UTI89 3993651 YP_542846.1 CDS damX NC_007946.1 3768688 3769974 R hypothetical protein complement(3768688..3769974) Escherichia coli UTI89 3993652 YP_542847.1 CDS aroB NC_007946.1 3770066 3771154 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3770066..3771154) Escherichia coli UTI89 3993653 YP_542848.1 CDS aroK NC_007946.1 3771211 3771933 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3771211..3771933) Escherichia coli UTI89 3993654 YP_542849.1 CDS hofQ NC_007946.1 3772133 3773371 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; porin complement(3772133..3773371) Escherichia coli UTI89 3993655 YP_542850.1 CDS yrfA NC_007946.1 3773283 3773726 R hypothetical protein complement(3773283..3773726) Escherichia coli UTI89 3993656 YP_542851.1 CDS yrfB NC_007946.1 3773677 3774117 R hypothetical protein complement(3773677..3774117) Escherichia coli UTI89 3993657 YP_542852.1 CDS yrfC NC_007946.1 3774101 3774640 R hypothetical protein complement(3774101..3774640) Escherichia coli UTI89 3993658 YP_542853.1 CDS yrfD NC_007946.1 3774640 3775446 R hypothetical protein complement(3774640..3775446) Escherichia coli UTI89 3991402 YP_542854.1 CDS mrcA NC_007946.1 3775515 3778091 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3775515..3778091 Escherichia coli UTI89 3991403 YP_542855.1 CDS nudE NC_007946.1 3778257 3778817 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3778257..3778817) Escherichia coli UTI89 3991404 YP_542856.1 CDS yrfF NC_007946.1 3779137 3781272 D IgaA-like membrane protein 3779137..3781272 Escherichia coli UTI89 3991405 YP_542857.1 CDS yrfG NC_007946.1 3781292 3782005 D phosphatase 3781292..3782005 Escherichia coli UTI89 3991406 YP_542858.1 CDS hlsR NC_007946.1 3782016 3782417 D synonym: b3400, hsp15, yrfH, EG12929; ribosome-associated heat shock protein Hsp15 3782016..3782417 Escherichia coli UTI89 3991407 YP_542859.1 CDS hslO NC_007946.1 3782436 3783320 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 3782436..3783320 Escherichia coli UTI89 3991408 YP_542860.1 CDS yhgE NC_007946.1 3783383 3785107 R transport complement(3783383..3785107) Escherichia coli UTI89 3991409 YP_542861.1 CDS UTI89_C3901 NC_007946.1 3785113 3785241 R hypothetical protein complement(3785113..3785241) Escherichia coli UTI89 3991410 YP_542862.1 CDS UTI89_C3902 NC_007946.1 3785183 3785314 R hypothetical protein complement(3785183..3785314) Escherichia coli UTI89 3991411 YP_542863.1 CDS pckA NC_007946.1 3785417 3787108 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3785417..3787108 Escherichia coli UTI89 3991412 YP_542864.1 CDS envZ NC_007946.1 3787184 3788536 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3787184..3788536) Escherichia coli UTI89 3991413 YP_542865.1 CDS ompR NC_007946.1 3788533 3789252 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3788533..3789252) Escherichia coli UTI89 3991414 YP_542866.1 CDS UTI89_C3906 NC_007946.1 3789342 3789527 R hypothetical protein complement(3789342..3789527) Escherichia coli UTI89 3991415 YP_542867.1 CDS greB NC_007946.1 3789444 3789956 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3789444..3789956 Escherichia coli UTI89 3991416 YP_542868.1 CDS yhgF NC_007946.1 3790053 3792374 D hypothetical protein 3790053..3792374 Escherichia coli UTI89 3991417 YP_542869.1 CDS feoA NC_007946.1 3792814 3793041 D ferrous iron transport protein A 3792814..3793041 Escherichia coli UTI89 3991418 YP_542870.1 CDS feoB NC_007946.1 3793046 3795379 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3793046..3795379 Escherichia coli UTI89 3991419 YP_542871.1 CDS yhgG NC_007946.1 3795390 3795626 D hypothetical protein 3795390..3795626 Escherichia coli UTI89 3991420 YP_542872.1 CDS yhgA NC_007946.1 3795829 3796722 D hypothetical protein 3795829..3796722 Escherichia coli UTI89 3994272 YP_542873.1 CDS bioH NC_007946.1 3796942 3797712 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3796942..3797712) Escherichia coli UTI89 3994273 YP_542874.2 CDS yhgH NC_007946.1 3797750 3798433 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3797750..3798433 Escherichia coli UTI89 3994274 YP_542875.1 CDS yhgI NC_007946.1 3798492 3799067 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3798492..3799067 Escherichia coli UTI89 3994275 YP_542876.1 CDS gntT NC_007946.1 3799428 3800744 D high-affinitygluconate permease 3799428..3800744 Escherichia coli UTI89 3994276 YP_542877.1 CDS malQ NC_007946.1 3800789 3802873 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3800789..3802873) Escherichia coli UTI89 3994277 YP_542878.1 CDS malP NC_007946.1 3802883 3805276 R maltodextrin phosphorylase complement(3802883..3805276) Escherichia coli UTI89 3994278 YP_542879.1 CDS malT NC_007946.1 3805899 3808604 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3805899..3808604 Escherichia coli UTI89 3994279 YP_542880.1 CDS rtcA NC_007946.1 3808647 3809666 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3808647..3809666) Escherichia coli UTI89 3994280 YP_542881.1 CDS rtcB NC_007946.1 3809667 3810956 R protein RtcB complement(3809667..3810956) Escherichia coli UTI89 3994281 YP_542882.1 CDS rtcR NC_007946.1 3811082 3812680 D transcriptional regulator RtcR 3811082..3812680 Escherichia coli UTI89 3994282 YP_542883.1 CDS glpR NC_007946.1 3812662 3813471 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3812662..3813471) Escherichia coli UTI89 3994283 YP_542884.1 CDS glpG NC_007946.1 3813437 3814267 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3813437..3814267) Escherichia coli UTI89 3994284 YP_542885.1 CDS glpE NC_007946.1 3814312 3814662 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3814312..3814662) Escherichia coli UTI89 3994285 YP_542886.2 CDS glpD NC_007946.1 3814828 3816333 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3814828..3816333 Escherichia coli UTI89 3994286 YP_542887.1 CDS UTI89_C3927 NC_007946.1 3816387 3816992 R hypothetical protein complement(3816387..3816992) Escherichia coli UTI89 3994287 YP_542888.1 CDS UTI89_C3928 NC_007946.1 3816995 3817762 R hypothetical protein complement(3816995..3817762) Escherichia coli UTI89 3994288 YP_542889.1 CDS aufG NC_007946.1 3817765 3818475 R hypothetical protein complement(3817765..3818475) Escherichia coli UTI89 3994289 YP_542890.1 CDS aufF NC_007946.1 3819783 3820583 R Auf fimbrial chaperone 2 complement(3819783..3820583) Escherichia coli UTI89 3994290 YP_542891.1 CDS aufE NC_007946.1 3820528 3821085 R Auf fimbriae minor subunit AufE complement(3820528..3821085) Escherichia coli UTI89 3994291 YP_542892.1 CDS aufD NC_007946.1 3821051 3821500 R Auf fimbriae minor subunit AufD complement(3821051..3821500) Escherichia coli UTI89 3993699 YP_542893.1 CDS UTI89_C3933 NC_007946.1 3821481 3821642 D hypothetical protein 3821481..3821642 Escherichia coli UTI89 3993700 YP_542894.1 CDS aufC NC_007946.1 3821614 3824208 R outer membrane usher protein AufC complement(3821614..3824208) Escherichia coli UTI89 3993701 YP_542895.1 CDS aufB NC_007946.1 3824245 3825024 R Auf fimbiral chaperone 1 complement(3824245..3825024) Escherichia coli UTI89 3993702 YP_542896.1 CDS aufA NC_007946.1 3825098 3825802 R Auf fimbriae major subunit AufA complement(3825098..3825802) Escherichia coli UTI89 3993703 YP_542897.1 CDS glgP NC_007946.1 3826296 3828743 R glycogen phosphorylase complement(3826296..3828743) Escherichia coli UTI89 3993704 YP_542898.1 CDS glgA NC_007946.1 3828762 3830195 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3828762..3830195) Escherichia coli UTI89 3993705 YP_542899.2 CDS glgC NC_007946.1 3830195 3831490 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3830195..3831490) Escherichia coli UTI89 3993706 YP_542900.1 CDS glgX NC_007946.1 3831508 3833481 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme complement(3831508..3833481) Escherichia coli UTI89 3993707 YP_542901.1 CDS glgB NC_007946.1 3833478 3835664 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme complement(3833478..3835664) Escherichia coli UTI89 3993708 YP_542902.1 CDS asd NC_007946.1 3835937 3837100 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3835937..3837100) Escherichia coli UTI89 3993709 YP_542903.1 CDS yhgN NC_007946.1 3837232 3837825 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3837232..3837825 Escherichia coli UTI89 3993710 YP_542904.1 CDS gntU NC_007946.1 3837882 3839222 R low affinity gluconate transporter complement(3837882..3839222) Escherichia coli UTI89 3993711 YP_542905.1 CDS gntK NC_007946.1 3839226 3839774 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 complement(3839226..3839774) Escherichia coli UTI89 3993712 YP_542906.1 CDS gntR NC_007946.1 3839892 3840887 R gluconate utilization system GNT-I transcriptional repressor complement(3839892..3840887) Escherichia coli UTI89 3993713 YP_542907.1 CDS yhhW NC_007946.1 3840980 3841675 R hypothetical protein complement(3840980..3841675) Escherichia coli UTI89 3993714 YP_542908.1 CDS yhhX NC_007946.1 3841798 3842835 R dehydrogenase complement(3841798..3842835) Escherichia coli UTI89 3993715 YP_542909.1 CDS UTI89_C3949 NC_007946.1 3842782 3842940 D hypothetical protein 3842782..3842940 Escherichia coli UTI89 3993716 YP_542910.1 CDS UTI89_C3950 NC_007946.1 3842892 3843146 R hypothetical protein complement(3842892..3843146) Escherichia coli UTI89 3993717 YP_542911.1 CDS UTI89_C3951 NC_007946.1 3843169 3843657 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3843169..3843657 Escherichia coli UTI89 3992892 YP_542912.1 CDS yrhA NC_007946.1 3845068 3845562 D hypothetical protein 3845068..3845562 Escherichia coli UTI89 3992893 YP_542913.1 CDS yrhB NC_007946.1 3846012 3846296 D hypothetical protein 3846012..3846296 Escherichia coli UTI89 3992894 YP_542914.1 CDS ggt NC_007946.1 3846334 3848067 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3846334..3848067) Escherichia coli UTI89 3992895 YP_542915.1 CDS yhhA NC_007946.1 3848187 3848627 D hypothetical protein 3848187..3848627 Escherichia coli UTI89 3992896 YP_542916.1 CDS ugpQ NC_007946.1 3848614 3849357 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase complement(3848614..3849357) Escherichia coli UTI89 3992897 YP_542917.2 CDS ugpC NC_007946.1 3849354 3850424 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3849354..3850424) Escherichia coli UTI89 3992898 YP_542918.1 CDS ugpE NC_007946.1 3850426 3851271 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3850426..3851271) Escherichia coli UTI89 3992899 YP_542919.1 CDS ugpA NC_007946.1 3851268 3852155 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3851268..3852155) Escherichia coli UTI89 3992900 YP_542920.1 CDS ugpB NC_007946.1 3852253 3853569 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3852253..3853569) Escherichia coli UTI89 3992901 YP_542921.2 CDS livF NC_007946.1 3853966 3854679 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3853966..3854679) Escherichia coli UTI89 3992902 YP_542922.1 CDS livG NC_007946.1 3854681 3855448 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3854681..3855448) Escherichia coli UTI89 3992903 YP_542923.1 CDS livM NC_007946.1 3855445 3856722 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3855445..3856722) Escherichia coli UTI89 3992904 YP_542924.1 CDS livH NC_007946.1 3856719 3857645 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3856719..3857645) Escherichia coli UTI89 3992905 YP_542925.1 CDS livK NC_007946.1 3857693 3858856 R leucine-specific binding protein complement(3857693..3858856) Escherichia coli UTI89 3992906 YP_542926.1 CDS UTI89_C3966 NC_007946.1 3858954 3859091 R hypothetical protein complement(3858954..3859091) Escherichia coli UTI89 3992907 YP_542927.1 CDS yhhK NC_007946.1 3859226 3859609 D acyltransferase 3859226..3859609 Escherichia coli UTI89 3992908 YP_542928.1 CDS UTI89_C3968 NC_007946.1 3859619 3859741 D hypothetical protein 3859619..3859741 Escherichia coli UTI89 3992909 YP_542929.1 CDS livJ NC_007946.1 3859797 3860957 R Leu/Ile/Val-binding protein complement(3859797..3860957) Escherichia coli UTI89 3992910 YP_542930.1 CDS UTI89_C3970 NC_007946.1 3861904 3862236 D phosphotransferase system protein 3861904..3862236 Escherichia coli UTI89 3992911 YP_542931.1 CDS UTI89_C3971 NC_007946.1 3862243 3862728 D phosphotransferase system protein 3862243..3862728 Escherichia coli UTI89 3994077 YP_542932.1 CDS UTI89_C3972 NC_007946.1 3862745 3863491 D phosphotransferase system protein 3862745..3863491 Escherichia coli UTI89 3994078 YP_542933.1 CDS UTI89_C3973 NC_007946.1 3863628 3864338 D phosphotransferase system protein 3863628..3864338 Escherichia coli UTI89 3994079 YP_542934.1 CDS UTI89_C3974 NC_007946.1 3864340 3865260 D phosphoglycerate dehydrogenase 3864340..3865260 Escherichia coli UTI89 3994080 YP_542935.1 CDS UTI89_C3975 NC_007946.1 3865260 3866144 D dihydrodipicolinate synthase 3865260..3866144 Escherichia coli UTI89 3994081 YP_542936.1 CDS rpoH NC_007946.1 3866248 3867102 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3866248..3867102) Escherichia coli UTI89 3994082 YP_542937.2 CDS ftsX NC_007946.1 3867347 3868405 R ABC transporter, membrane protein; cell division protein FtsX complement(3867347..3868405) Escherichia coli UTI89 3994083 YP_542938.1 CDS ftsE NC_007946.1 3868398 3869066 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3868398..3869066) Escherichia coli UTI89 3994084 YP_542939.1 CDS ftsY NC_007946.1 3869069 3870565 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3869069..3870565) Escherichia coli UTI89 3994085 YP_542940.1 CDS rsmD NC_007946.1 3870715 3871311 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3870715..3871311 Escherichia coli UTI89 3994086 YP_542941.1 CDS yhhL NC_007946.1 3871298 3871570 D hypothetical protein 3871298..3871570 Escherichia coli UTI89 3994087 YP_542942.1 CDS yhhM NC_007946.1 3871573 3871932 R hypothetical protein complement(3871573..3871932) Escherichia coli UTI89 3994088 YP_542943.1 CDS yhhN NC_007946.1 3872073 3872699 D hypothetical protein 3872073..3872699 Escherichia coli UTI89 3994089 YP_542944.1 CDS zntA NC_007946.1 3872773 3874971 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3872773..3874971 Escherichia coli UTI89 3994090 YP_542945.1 CDS UTI89_C3985 NC_007946.1 3875201 3875503 D hypothetical protein 3875201..3875503 Escherichia coli UTI89 3994091 YP_542946.1 CDS sira NC_007946.1 3875240 3875485 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3875240..3875485) Escherichia coli UTI89 3994092 YP_542947.1 CDS yhhQ NC_007946.1 3875706 3876371 D hypothetical protein 3875706..3876371 Escherichia coli UTI89 3994093 YP_542948.2 CDS UTI89_C3988 NC_007946.1 3876444 3877001 D hypothetical protein 3876444..3877001 Escherichia coli UTI89 3994094 YP_542949.2 CDS yhhS NC_007946.1 3877005 3878222 R major facilitator superfamily transporter complement(3877005..3878222) Escherichia coli UTI89 3994095 YP_542950.1 CDS yhhT NC_007946.1 3878273 3879403 D hypothetical protein 3878273..3879403 Escherichia coli UTI89 3991499 YP_542951.1 CDS acpT NC_007946.1 3879458 3880045 D synonym: b3475, yhhU; holo-(acyl carrier protein) synthase 2 3879458..3880045 Escherichia coli UTI89 3991500 YP_542952.1 CDS UTI89_C3992 NC_007946.1 3879955 3880131 R hypothetical protein complement(3879955..3880131) Escherichia coli UTI89 3991501 YP_542953.1 CDS nikA NC_007946.1 3880156 3881730 D nickel-binding periplasmic protein 3880156..3881730 Escherichia coli UTI89 3991502 YP_542954.1 CDS nikB NC_007946.1 3881730 3882674 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3881730..3882674 Escherichia coli UTI89 3991503 YP_542955.1 CDS nikC NC_007946.1 3882671 3883504 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3882671..3883504 Escherichia coli UTI89 3991504 YP_542956.1 CDS nikD NC_007946.1 3883504 3884268 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3883504..3884268 Escherichia coli UTI89 3991505 YP_542957.1 CDS nikE NC_007946.1 3884265 3885071 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3884265..3885071 Escherichia coli UTI89 3991506 YP_542958.1 CDS nikR NC_007946.1 3885077 3885478 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3885077..3885478 Escherichia coli UTI89 3991507 YP_542959.1 CDS UTI89_C3999 NC_007946.1 3885668 3886423 D regulator 3885668..3886423 Escherichia coli UTI89 3991508 YP_542960.1 CDS UTI89_C4000 NC_007946.1 3886448 3886921 D phosphotransferase system enzyme subunit 3886448..3886921 Escherichia coli UTI89 3991509 YP_542961.1 CDS UTI89_C4001 NC_007946.1 3886918 3887199 D phosphotransferase system enzyme subunit 3886918..3887199 Escherichia coli UTI89 3991510 YP_542962.1 CDS UTI89_C4002 NC_007946.1 3887246 3888634 D PTS system galactitol-specific transporter subunit IIC 3887246..3888634 Escherichia coli UTI89 3991511 YP_542963.1 CDS UTI89_C4003 NC_007946.1 3888627 3890135 D xylulose kinase 3888627..3890135 Escherichia coli UTI89 3991512 YP_542964.1 CDS UTI89_C4004 NC_007946.1 3890125 3890394 D phosphocarrier protein 3890125..3890394 Escherichia coli UTI89 3991513 YP_542965.1 CDS gatY NC_007946.1 3890426 3891277 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3890426..3891277 Escherichia coli UTI89 3991514 YP_542966.1 CDS yhhJ NC_007946.1 3891387 3892595 R hypothetical protein complement(3891387..3892595) Escherichia coli UTI89 3991515 YP_542967.1 CDS yhiH NC_007946.1 3892511 3895246 R ABC transporter ATP-binding protein complement(3892511..3895246) Escherichia coli UTI89 3991516 YP_542968.1 CDS yhiI NC_007946.1 3895243 3896310 R hypothetical protein complement(3895243..3896310) Escherichia coli UTI89 3991517 YP_542969.1 CDS UTI89_C4009 NC_007946.1 3896303 3896434 R hypothetical protein complement(3896303..3896434) Escherichia coli UTI89 3991518 YP_542970.1 CDS yhiM NC_007946.1 3897032 3898096 D hypothetical protein 3897032..3898096 Escherichia coli UTI89 3991241 YP_542971.1 CDS yhiN NC_007946.1 3898183 3899376 R hypothetical protein complement(3898183..3899376) Escherichia coli UTI89 3991242 YP_542972.1 CDS pitA NC_007946.1 3899608 3901107 D low-affinity phosphate transport 3899608..3901107 Escherichia coli UTI89 3991243 YP_542973.1 CDS uspB NC_007946.1 3901178 3901513 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3901178..3901513) Escherichia coli UTI89 3991244 YP_542974.1 CDS uspA NC_007946.1 3901904 3902338 D universal stress protein A 3901904..3902338 Escherichia coli UTI89 3991245 YP_542975.1 CDS yhiP NC_007946.1 3902655 3904124 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3902655..3904124 Escherichia coli UTI89 3991246 YP_542976.2 CDS yhiQ NC_007946.1 3904173 3904925 R predicted SAM-dependent methyltransferase; methyltransferase complement(3904173..3904925) Escherichia coli UTI89 3991247 YP_542977.1 CDS prlC NC_007946.1 3904933 3907014 R synonym: b3498, opdA; oligopeptidase A complement(3904933..3907014) Escherichia coli UTI89 3991248 YP_542978.1 CDS yhiR NC_007946.1 3907127 3908020 D hypothetical protein 3907127..3908020 Escherichia coli UTI89 3991249 YP_542979.1 CDS gor NC_007946.1 3908092 3909444 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3908092..3909444 Escherichia coli UTI89 3991250 YP_542980.1 CDS UTI89_C4020 NC_007946.1 3909498 3909647 R hypothetical protein complement(3909498..3909647) Escherichia coli UTI89 3991251 YP_542981.1 CDS arsC NC_007946.1 3910115 3910540 D arsenate reductase 3910115..3910540 Escherichia coli UTI89 3991252 YP_542982.1 CDS UTI89_C4022 NC_007946.1 3910594 3910758 D hypothetical protein 3910594..3910758 Escherichia coli UTI89 3991253 YP_542983.1 CDS UTI89_C4023 NC_007946.1 3911157 3911330 D hypothetical protein 3911157..3911330 Escherichia coli UTI89 3991254 YP_542984.1 CDS slp NC_007946.1 3911691 3912290 D starvation induced outer membrane protein 3911691..3912290 Escherichia coli UTI89 3991255 YP_542985.1 CDS UTI89_C4025 NC_007946.1 3912331 3912504 D hypothetical protein 3912331..3912504 Escherichia coli UTI89 3991256 YP_542986.1 CDS yhiF NC_007946.1 3912443 3912973 D transcriptional regulator YhiF 3912443..3912973 Escherichia coli UTI89 3991257 YP_542987.1 CDS chuS NC_007946.1 3913030 3914058 R heme/hemoglobin transport protein complement(3913030..3914058) Escherichia coli UTI89 3991258 YP_542988.1 CDS chuA NC_007946.1 3914107 3916089 R outer membrane hemin receptor ChuA complement(3914107..3916089) Escherichia coli UTI89 3991259 YP_542989.1 CDS UTI89_C4029 NC_007946.1 3916028 3916186 D hypothetical protein 3916028..3916186 Escherichia coli UTI89 3990017 YP_542990.1 CDS UTI89_C4030 NC_007946.1 3916190 3916375 R hypothetical protein complement(3916190..3916375) Escherichia coli UTI89 3990018 YP_542991.1 CDS UTI89_C4031 NC_007946.1 3916458 3916619 D hypothetical protein 3916458..3916619 Escherichia coli UTI89 3990019 YP_542992.1 CDS UTI89_C4032 NC_007946.1 3916501 3916650 R hypothetical protein complement(3916501..3916650) Escherichia coli UTI89 3990020 YP_542993.1 CDS chuT NC_007946.1 3916695 3917687 D periplasmic binding protein 3916695..3917687 Escherichia coli UTI89 3990021 YP_542994.1 CDS chuW NC_007946.1 3917707 3919044 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3917707..3919044 Escherichia coli UTI89 3990022 YP_542995.1 CDS chuX NC_007946.1 3919057 3919551 D hypothetical protein 3919057..3919551 Escherichia coli UTI89 3990023 YP_542996.1 CDS chuY NC_007946.1 3919551 3920174 D hypothetical protein 3919551..3920174 Escherichia coli UTI89 3990024 YP_542997.1 CDS chuU NC_007946.1 3920223 3921215 D permease of iron compound ABC transport system 3920223..3921215 Escherichia coli UTI89 3990025 YP_542998.1 CDS hmuV NC_007946.1 3921182 3921982 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3921182..3921982 Escherichia coli UTI89 3990026 YP_542999.1 CDS yhiD NC_007946.1 3922034 3922681 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(3922034..3922681) Escherichia coli UTI89 3990027 YP_543000.1 CDS hdeB NC_007946.1 3922745 3923083 R acid-resistance protein complement(3922745..3923083) Escherichia coli UTI89 3990028 YP_543001.1 CDS hdeA NC_007946.1 3923187 3923519 R inactive form; acid-resistance protein complement(3923187..3923519) Escherichia coli UTI89 3990029 YP_543002.1 CDS hdeD NC_007946.1 3923774 3924346 D acid-resistance membrane protein 3923774..3924346 Escherichia coli UTI89 3990030 YP_543003.1 CDS yhiE NC_007946.1 3925067 3925672 D hypothetical protein 3925067..3925672 Escherichia coli UTI89 3990031 YP_543004.1 CDS UTI89_C4044 NC_007946.1 3925716 3926009 D hypothetical protein 3925716..3926009 Escherichia coli UTI89 3990032 YP_543005.1 CDS yhiU NC_007946.1 3926011 3927168 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3926011..3927168 Escherichia coli UTI89 3990033 YP_543006.1 CDS yhiV NC_007946.1 3927193 3930306 D hypothetical protein 3927193..3930306 Escherichia coli UTI89 3990034 YP_543007.1 CDS yhiW NC_007946.1 3930669 3931397 R transcriptional regulator YhiW complement(3930669..3931397) Escherichia coli UTI89 3990035 YP_543008.1 CDS yhiX NC_007946.1 3931766 3932590 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3931766..3932590) Escherichia coli UTI89 3990036 YP_543009.1 CDS gadA NC_007946.1 3932958 3934421 R glutamate decarboxylase alpha complement(3932958..3934421) Escherichia coli UTI89 3991128 YP_543010.1 CDS yhjA NC_007946.1 3934569 3935966 R cytochrome C peroxidase complement(3934569..3935966) Escherichia coli UTI89 3991129 YP_543011.1 CDS treF NC_007946.1 3936371 3938020 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3936371..3938020 Escherichia coli UTI89 3991130 YP_543012.1 CDS yhjB NC_007946.1 3938071 3938673 R transcriptional regulator YhjB complement(3938071..3938673) Escherichia coli UTI89 3991131 YP_543013.1 CDS yhjC NC_007946.1 3939121 3940092 D transcriptional regulator YhjC 3939121..3940092 Escherichia coli UTI89 3991132 YP_543014.1 CDS yhjD NC_007946.1 3940141 3941154 D hypothetical protein 3940141..3941154 Escherichia coli UTI89 3991133 YP_543015.1 CDS yhjE NC_007946.1 3941547 3942869 D metabolite transport protein YhjE 3941547..3942869 Escherichia coli UTI89 3991134 YP_543016.1 CDS yhjG NC_007946.1 3942910 3944985 R hypothetical protein complement(3942910..3944985) Escherichia coli UTI89 3991135 YP_543017.1 CDS yhjH NC_007946.1 3945040 3945810 R in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase complement(3945040..3945810) Escherichia coli UTI89 3991136 YP_543018.1 CDS kdgK NC_007946.1 3945691 3946968 D 2-dehydro-3-deoxygluconokinase 3945691..3946968 Escherichia coli UTI89 3991137 YP_543019.1 CDS yhjJ NC_007946.1 3947064 3948560 R protein YhjJ complement(3947064..3948560) Escherichia coli UTI89 3991138 YP_543020.1 CDS dctA NC_007946.1 3948780 3950066 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3948780..3950066) Escherichia coli UTI89 3991139 YP_543021.1 CDS yhjK NC_007946.1 3950249 3952237 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase complement(3950249..3952237) Escherichia coli UTI89 3991140 YP_543022.1 CDS yhjL NC_007946.1 3952319 3955792 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3952319..3955792) Escherichia coli UTI89 3991141 YP_543023.1 CDS yhjM NC_007946.1 3955774 3956886 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3955774..3956886) Escherichia coli UTI89 3991142 YP_543024.1 CDS yhjN NC_007946.1 3956887 3959313 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3956887..3959313) Escherichia coli UTI89 3991143 YP_543025.2 CDS bcsA NC_007946.1 3959237 3961855 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3959237..3961855) Escherichia coli UTI89 3991144 YP_543026.1 CDS yhjQ NC_007946.1 3961852 3962604 R cell division protein complement(3961852..3962604) Escherichia coli UTI89 3991145 YP_543027.1 CDS yhjR NC_007946.1 3962616 3962804 R hypothetical protein complement(3962616..3962804) Escherichia coli UTI89 3991146 YP_543028.1 CDS yhjS NC_007946.1 3963077 3964648 D hypothetical protein 3963077..3964648 Escherichia coli UTI89 3989626 YP_543029.1 CDS yhjT NC_007946.1 3964645 3964836 D hypothetical protein 3964645..3964836 Escherichia coli UTI89 3989627 YP_543030.1 CDS yhjU NC_007946.1 3964833 3966512 D hypothetical protein 3964833..3966512 Escherichia coli UTI89 3989628 YP_543031.1 CDS UTI89_C4071 NC_007946.1 3966598 3966840 R hypothetical protein complement(3966598..3966840) Escherichia coli UTI89 3989629 YP_543032.1 CDS UTI89_C4072 NC_007946.1 3966777 3967076 D hypothetical protein 3966777..3967076 Escherichia coli UTI89 3989630 YP_543033.1 CDS UTI89_C4073 NC_007946.1 3967081 3967323 R hypothetical protein complement(3967081..3967323) Escherichia coli UTI89 3989631 YP_543034.1 CDS UTI89_C4074 NC_007946.1 3967230 3967547 D hypothetical protein 3967230..3967547 Escherichia coli UTI89 3989632 YP_543035.1 CDS UTI89_C4075 NC_007946.1 3967563 3967838 R hypothetical protein complement(3967563..3967838) Escherichia coli UTI89 3989633 YP_543036.1 CDS UTI89_C4076 NC_007946.1 3967835 3967996 R hypothetical protein complement(3967835..3967996) Escherichia coli UTI89 3989634 YP_543037.1 CDS yhjV NC_007946.1 3968083 3969417 D transport protein YhjV 3968083..3969417 Escherichia coli UTI89 3989635 YP_543038.1 CDS dppF NC_007946.1 3969447 3970451 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(3969447..3970451) Escherichia coli UTI89 3989636 YP_543039.1 CDS dppD NC_007946.1 3970448 3971431 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(3970448..3971431) Escherichia coli UTI89 3989637 YP_543040.1 CDS dppC NC_007946.1 3971442 3972344 R dipeptide transporter complement(3971442..3972344) Escherichia coli UTI89 3989638 YP_543041.1 CDS dppB NC_007946.1 3972354 3973373 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(3972354..3973373) Escherichia coli UTI89 3989639 YP_543042.1 CDS dppA NC_007946.1 3973524 3975131 R periplasmic dipeptide transport protein complement(3973524..3975131) Escherichia coli UTI89 3989640 YP_543043.1 CDS UTI89_C4083 NC_007946.1 3975320 3975475 D hypothetical protein 3975320..3975475 Escherichia coli UTI89 3989641 YP_543045.2 CDS yhjW NC_007946.1 3976040 3977731 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(3976040..3977731) Escherichia coli UTI89 3989644 YP_543046.1 CDS yhjX NC_007946.1 3978055 3979308 R resistance protein complement(3978055..3979308) Escherichia coli UTI89 3991260 YP_543047.1 CDS yhjY NC_007946.1 3979492 3980196 R hypothetical protein complement(3979492..3980196) Escherichia coli UTI89 3991261 YP_543048.2 CDS tag NC_007946.1 3980348 3980911 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 3980348..3980911 Escherichia coli UTI89 3991262 YP_543049.1 CDS yiaC NC_007946.1 3980908 3981348 D hypothetical protein 3980908..3981348 Escherichia coli UTI89 3991263 YP_543050.1 CDS bisC NC_007946.1 3981317 3983650 R biotin sulfoxide reductase complement(3981317..3983650) Escherichia coli UTI89 3991264 YP_543051.1 CDS yiaD NC_007946.1 3983803 3984462 D outer membrane lipoprotein 3983803..3984462 Escherichia coli UTI89 3991265 YP_543052.1 CDS yiaE NC_007946.1 3984554 3985540 D dehydrogenase 3984554..3985540 Escherichia coli UTI89 3991266 YP_543053.1 CDS yiaF NC_007946.1 3985590 3986420 R hypothetical protein complement(3985590..3986420) Escherichia coli UTI89 3991267 YP_543054.1 CDS yiaG NC_007946.1 3986734 3987024 D transcriptional regulator 3986734..3987024 Escherichia coli UTI89 3991268 YP_543055.1 CDS UTI89_C4096 NC_007946.1 3987242 3987664 R hypothetical protein complement(3987242..3987664) Escherichia coli UTI89 3991269 YP_543056.1 CDS cspA NC_007946.1 3987305 3987517 D cold-shock protein 3987305..3987517 Escherichia coli UTI89 3991270 YP_543057.1 CDS UTI89_C4098 NC_007946.1 3987705 3987917 R small toxic polypeptide complement(3987705..3987917) Escherichia coli UTI89 3991271 YP_543058.1 CDS glyS NC_007946.1 3988180 3990249 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(3988180..3990249) Escherichia coli UTI89 3991272 YP_543059.1 CDS glyQ NC_007946.1 3990259 3991170 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(3990259..3991170) Escherichia coli UTI89 3991273 YP_543060.1 CDS UTI89_C4101 NC_007946.1 3991265 3991564 R hypothetical protein complement(3991265..3991564) Escherichia coli UTI89 3991274 YP_543061.1 CDS yiaH NC_007946.1 3991739 3992734 D hypothetical protein 3991739..3992734 Escherichia coli UTI89 3991275 YP_543062.1 CDS yiaA NC_007946.1 3992776 3993216 R hypothetical protein complement(3992776..3993216) Escherichia coli UTI89 3991276 YP_543063.1 CDS yiaB NC_007946.1 3993259 3993642 R hypothetical protein complement(3993259..3993642) Escherichia coli UTI89 3991277 YP_543064.1 CDS xylB NC_007946.1 3993769 3995223 R xylulokinase complement(3993769..3995223) Escherichia coli UTI89 3991278 YP_543065.2 CDS xylA NC_007946.1 3995295 3996617 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(3995295..3996617) Escherichia coli UTI89 3993812 YP_543066.1 CDS xylF NC_007946.1 3996905 3997975 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3996905..3997975 Escherichia coli UTI89 3993813 YP_543067.1 CDS xylG NC_007946.1 3998017 3999594 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3998017..3999594 Escherichia coli UTI89 3993814 YP_543068.1 CDS xylH NC_007946.1 3999572 4000753 D xylose transport system permease xylH 3999572..4000753 Escherichia coli UTI89 3993815 YP_543069.1 CDS xylR NC_007946.1 4000831 4002009 D regulator of xyl operon 4000831..4002009 Escherichia coli UTI89 3993816 YP_543070.1 CDS bax NC_007946.1 4002117 4002941 R hypothetical protein complement(4002117..4002941) Escherichia coli UTI89 3993817 YP_543071.1 CDS UTI89_C4112 NC_007946.1 4003091 4003264 D hypothetical protein 4003091..4003264 Escherichia coli UTI89 3993818 YP_543072.1 CDS malS NC_007946.1 4003261 4005291 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4003261..4005291 Escherichia coli UTI89 3993819 YP_543073.1 CDS avtA NC_007946.1 4005364 4006722 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4005364..4006722 Escherichia coli UTI89 3993820 YP_543074.1 CDS ysaA NC_007946.1 4006874 4007353 R synonym: yiaI, b3573; electron transport protein YsaA complement(4006874..4007353) Escherichia coli UTI89 3993821 YP_543075.1 CDS yiaJ NC_007946.1 4007449 4008297 R transcriptional regulator YiaJ complement(4007449..4008297) Escherichia coli UTI89 3993822 YP_543076.1 CDS yiaK NC_007946.1 4008498 4009496 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4008498..4009496 Escherichia coli UTI89 3993823 YP_543077.1 CDS yiaL NC_007946.1 4009508 4009972 D hypothetical protein 4009508..4009972 Escherichia coli UTI89 3993824 YP_543078.1 CDS UTI89_C4119 NC_007946.1 4009995 4010915 D hypothetical protein 4009995..4010915 Escherichia coli UTI89 3993825 YP_543079.1 CDS yiaM NC_007946.1 4011029 4011496 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 4011029..4011496 Escherichia coli UTI89 3993826 YP_543080.1 CDS yiaN NC_007946.1 4011499 4012776 D hypothetical protein 4011499..4012776 Escherichia coli UTI89 3993827 YP_543081.1 CDS UTI89_C4122 NC_007946.1 4012764 4012886 D hypothetical protein 4012764..4012886 Escherichia coli UTI89 3993828 YP_543082.1 CDS yiaO NC_007946.1 4012789 4013775 D ABC transporter periplasmic binding protein yiaO 4012789..4013775 Escherichia coli UTI89 3993829 YP_543083.1 CDS lyxK NC_007946.1 4013779 4015275 D cryptic L-xylulose kinase 4013779..4015275 Escherichia coli UTI89 3993830 YP_543084.1 CDS sgbH NC_007946.1 4015272 4015934 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4015272..4015934 Escherichia coli UTI89 3993831 YP_543085.1 CDS sgbU NC_007946.1 4015894 4016787 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4015894..4016787 Escherichia coli UTI89 3991013 YP_543086.1 CDS sgbE NC_007946.1 4016781 4017476 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4016781..4017476 Escherichia coli UTI89 3991014 YP_543087.1 CDS UTI89_C4128 NC_007946.1 4016784 4017521 R hypothetical protein complement(4016784..4017521) Escherichia coli UTI89 3991015 YP_543088.1 CDS aldB NC_007946.1 4017523 4019151 R aldehyde dehydrogenase complement(4017523..4019151) Escherichia coli UTI89 3991016 YP_543089.1 CDS UTI89_C4130 NC_007946.1 4019169 4020464 R hypothetical protein complement(4019169..4020464) Escherichia coli UTI89 3991017 YP_543090.1 CDS yiaY NC_007946.1 4020594 4021745 R alcohol dehydrogenase complement(4020594..4021745) Escherichia coli UTI89 3991018 YP_543091.1 CDS selB NC_007946.1 4021936 4023780 R selenocysteinyl-tRNA-specific translation factor complement(4021936..4023780) Escherichia coli UTI89 3991019 YP_543092.1 CDS selA NC_007946.1 4023777 4025168 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4023777..4025168) Escherichia coli UTI89 3991020 YP_543093.1 CDS yibF NC_007946.1 4025266 4025874 R glutathione S-transferase complement(4025266..4025874) Escherichia coli UTI89 3991021 YP_543094.1 CDS yibH NC_007946.1 4025945 4027081 R hypothetical protein complement(4025945..4027081) Escherichia coli UTI89 3991022 YP_543095.1 CDS yibI NC_007946.1 4027084 4027446 R hypothetical protein complement(4027084..4027446) Escherichia coli UTI89 3991023 YP_543096.1 CDS mtlA NC_007946.1 4027982 4029895 D mannitol-specific PTS system enzyme IIABC components 4027982..4029895 Escherichia coli UTI89 3991024 YP_543097.1 CDS mtlD NC_007946.1 4030034 4031362 D mannitol-1-phosphate 5-dehydrogenase 4030034..4031362 Escherichia coli UTI89 3991025 YP_543098.1 CDS mtlR NC_007946.1 4031362 4031949 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4031362..4031949 Escherichia coli UTI89 3991026 YP_543099.1 CDS UTI89_C4140 NC_007946.1 4031960 4032169 R hypothetical protein complement(4031960..4032169) Escherichia coli UTI89 3991027 YP_543100.1 CDS yibL NC_007946.1 4032453 4032815 D hypothetical protein 4032453..4032815 Escherichia coli UTI89 3991028 YP_543101.1 CDS UTI89_C4142 NC_007946.1 4033071 4033238 R hypothetical protein complement(4033071..4033238) Escherichia coli UTI89 3991029 YP_543102.1 CDS UTI89_C4143 NC_007946.1 4034101 4038852 D autotransport adhesin 4034101..4038852 Escherichia coli UTI89 3991030 YP_543103.1 CDS lldP NC_007946.1 4039241 4040917 D L-lactate permease 4039241..4040917 Escherichia coli UTI89 3991031 YP_543104.1 CDS lldR NC_007946.1 4040902 4041693 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4040902..4041693 Escherichia coli UTI89 3989606 YP_543105.1 CDS lldD NC_007946.1 4041690 4042880 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4041690..4042880 Escherichia coli UTI89 3989607 YP_543106.1 CDS yibK NC_007946.1 4042928 4043401 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4042928..4043401 Escherichia coli UTI89 3989608 YP_543107.1 CDS cysE NC_007946.1 4043456 4044277 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4043456..4044277) Escherichia coli UTI89 3989609 YP_543108.1 CDS gpsA NC_007946.1 4044357 4045376 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4044357..4045376) Escherichia coli UTI89 3989610 YP_543109.1 CDS UTI89_C4150 NC_007946.1 4045355 4045840 D hypothetical protein 4045355..4045840 Escherichia coli UTI89 3989611 YP_543110.1 CDS secB NC_007946.1 4045376 4045903 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4045376..4045903) Escherichia coli UTI89 3989612 YP_543111.1 CDS grxC NC_007946.1 4045907 4046158 R glutaredoxin 3 complement(4045907..4046158) Escherichia coli UTI89 3989613 YP_543112.1 CDS UTI89_C4153 NC_007946.1 4045973 4046242 D hypothetical protein 4045973..4046242 Escherichia coli UTI89 3989614 YP_543113.1 CDS UTI89_C4154 NC_007946.1 4046255 4046413 R hypothetical protein complement(4046255..4046413) Escherichia coli UTI89 3989615 YP_543114.1 CDS yibN NC_007946.1 4046299 4046742 R hypothetical protein complement(4046299..4046742) Escherichia coli UTI89 3989616 YP_543115.1 CDS UTI89_C4156 NC_007946.1 4046754 4046951 D hypothetical protein 4046754..4046951 Escherichia coli UTI89 3989617 YP_543116.2 CDS yibO NC_007946.1 4046975 4048519 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4046975..4048519 Escherichia coli UTI89 3989618 YP_543117.1 CDS yibP NC_007946.1 4048529 4049812 D hypothetical protein 4048529..4049812 Escherichia coli UTI89 3989619 YP_543118.1 CDS yibQ NC_007946.1 4049816 4050775 D hypothetical protein 4049816..4050775 Escherichia coli UTI89 3989620 YP_543119.1 CDS yibD NC_007946.1 4050762 4051796 R glycosyl transferase complement(4050762..4051796) Escherichia coli UTI89 3989621 YP_543120.1 CDS UTI89_C4161 NC_007946.1 4052026 4053051 D hypothetical protein 4052026..4053051 Escherichia coli UTI89 3989622 YP_543121.1 CDS tdh NC_007946.1 4052035 4053060 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4052035..4053060) Escherichia coli UTI89 3989623 YP_543122.1 CDS kbl NC_007946.1 4053070 4054266 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase complement(4053070..4054266) Escherichia coli UTI89 3989624 YP_543123.1 CDS rfaD NC_007946.1 4054480 4055412 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4054480..4055412 Escherichia coli UTI89 3989625 YP_543124.1 CDS rfaF NC_007946.1 4055422 4056468 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4055422..4056468 Escherichia coli UTI89 3991051 YP_543125.1 CDS rfaC NC_007946.1 4056472 4057452 D synonym: b3621, rfa-2, rfa2, waaC, yibC; ADP-heptose:LPS heptosyl transferase I 4056472..4057452 Escherichia coli UTI89 3991052 YP_543126.1 CDS waaL NC_007946.1 4057522 4058775 R lipid A-core surface polymer ligase complement(4057522..4058775) Escherichia coli UTI89 3991053 YP_543127.1 CDS waaV NC_007946.1 4058821 4059804 R beta1,3-glucosyltransferase complement(4058821..4059804) Escherichia coli UTI89 3991054 YP_543128.1 CDS waaW NC_007946.1 4059886 4060914 R UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase complement(4059886..4060914) Escherichia coli UTI89 3991055 YP_543129.1 CDS rfaY NC_007946.1 4060940 4061632 R synonym: b3625, waaY; lipopolysaccharide core biosynthesis protein complement(4060940..4061632) Escherichia coli UTI89 3991056 YP_543130.1 CDS rfaJ NC_007946.1 4061642 4062637 R synonym: b3626, waaJ, waaR; lipopolysaccharide 1,2-glucosyltransferase complement(4061642..4062637) Escherichia coli UTI89 3991057 YP_543131.1 CDS rafI NC_007946.1 4062654 4063670 R synonym: b3627, waaI, waaO; lipopolysaccharide 1,3-galactosyltransferase complement(4062654..4063670) Escherichia coli UTI89 3991058 YP_543132.1 CDS rfaP NC_007946.1 4063686 4064492 R synonym: b3630, waaP; lipopolysaccharide core biosynthesis protein rfaP complement(4063686..4064492) Escherichia coli UTI89 3991059 YP_543133.1 CDS rfaG NC_007946.1 4064476 4065600 R synonym: b3631, pcsA, waaG; lipopolysaccharide core biosynthesis glucosyltransferase I complement(4064476..4065600) Escherichia coli UTI89 3991060 YP_543134.1 CDS rfaQ NC_007946.1 4065597 4066655 R lipopolysaccharide core biosynthesis protein complement(4065597..4066655) Escherichia coli UTI89 3991061 YP_543135.1 CDS kdtA NC_007946.1 4067068 4068345 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4067068..4068345 Escherichia coli UTI89 3991062 YP_543136.1 CDS coaD NC_007946.1 4068353 4068832 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4068353..4068832 Escherichia coli UTI89 3991063 YP_543137.1 CDS mutM NC_007946.1 4068871 4069680 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4068871..4069680) Escherichia coli UTI89 3991064 YP_543138.1 CDS UTI89_C4179 NC_007946.1 4069694 4069969 D hypothetical protein 4069694..4069969 Escherichia coli UTI89 3991065 YP_543139.1 CDS rpmG NC_007946.1 4069778 4069945 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4069778..4069945) Escherichia coli UTI89 3991066 YP_543140.1 CDS rpmB NC_007946.1 4069966 4070202 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4069966..4070202) Escherichia coli UTI89 3991067 YP_543141.1 CDS radC NC_007946.1 4070419 4071093 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4070419..4071093) Escherichia coli UTI89 3991068 YP_543142.1 CDS dfp NC_007946.1 4071187 4072479 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4071187..4072479 Escherichia coli UTI89 3991069 YP_543143.1 CDS dut NC_007946.1 4072457 4072915 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4072457..4072915 Escherichia coli UTI89 3991318 YP_543144.2 CDS slmA NC_007946.1 4073022 4073618 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4073022..4073618 Escherichia coli UTI89 3991319 YP_543145.2 CDS pyrE NC_007946.1 4073655 4074296 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4073655..4074296) Escherichia coli UTI89 3991320 YP_543146.2 CDS rph NC_007946.1 4074362 4075078 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4074362..4075078) Escherichia coli UTI89 3991321 YP_543147.1 CDS yicC NC_007946.1 4075205 4076068 D hypothetical protein 4075205..4076068 Escherichia coli UTI89 3991322 YP_543148.2 CDS dinD NC_007946.1 4076290 4077114 D DNA-damage-inducible protein D 4076290..4077114 Escherichia coli UTI89 3991323 YP_543149.1 CDS yicG NC_007946.1 4077352 4078023 D hypothetical protein 4077352..4078023 Escherichia coli UTI89 3991324 YP_543150.1 CDS ligB NC_007946.1 4078020 4079708 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4078020..4079708) Escherichia coli UTI89 3991325 YP_543151.1 CDS UTI89_C4192 NC_007946.1 4079563 4079826 R hypothetical protein complement(4079563..4079826) Escherichia coli UTI89 3991326 YP_543152.1 CDS gmk NC_007946.1 4079903 4080583 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4079903..4080583 Escherichia coli UTI89 3991327 YP_543153.1 CDS rpoZ NC_007946.1 4080638 4080913 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4080638..4080913 Escherichia coli UTI89 3991328 YP_543154.1 CDS spoT NC_007946.1 4080932 4083040 D bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4080932..4083040 Escherichia coli UTI89 3991329 YP_543155.1 CDS spoU NC_007946.1 4083047 4083736 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4083047..4083736 Escherichia coli UTI89 3991330 YP_543156.2 CDS recG NC_007946.1 4083742 4085823 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4083742..4085823 Escherichia coli UTI89 3991331 YP_543157.1 CDS UTI89_C4198 NC_007946.1 4085857 4087062 R glutamate transport protein complement(4085857..4087062) Escherichia coli UTI89 3991332 YP_543158.1 CDS yicE NC_007946.1 4087333 4088733 D transport protein 4087333..4088733 Escherichia coli UTI89 3991333 YP_543159.1 CDS yicH NC_007946.1 4088830 4090563 D hypothetical protein 4088830..4090563 Escherichia coli UTI89 3991334 YP_543160.1 CDS UTI89_C4201 NC_007946.1 4090607 4091326 R hypothetical protein complement(4090607..4091326) Escherichia coli UTI89 3991335 YP_543161.1 CDS UTI89_C4202 NC_007946.1 4091268 4092233 R hypothetical protein complement(4091268..4092233) Escherichia coli UTI89 3991336 YP_543162.1 CDS UTI89_C4203 NC_007946.1 4092248 4093108 R hypothetical protein complement(4092248..4093108) Escherichia coli UTI89 3991337 YP_543163.1 CDS UTI89_C4204 NC_007946.1 4093189 4094040 R aldolase complement(4093189..4094040) Escherichia coli UTI89 3991481 YP_543164.1 CDS UTI89_C4205 NC_007946.1 4094052 4095143 R PTS enzyme-II fructose complement(4094052..4095143) Escherichia coli UTI89 3991482 YP_543165.1 CDS UTI89_C4206 NC_007946.1 4095168 4095482 R PTS system fructose-like transporter subunit IIB complement(4095168..4095482) Escherichia coli UTI89 3991483 YP_543166.1 CDS UTI89_C4207 NC_007946.1 4095500 4095970 R phosphotransferase system (PTS), fructose-specific complement(4095500..4095970) Escherichia coli UTI89 3991484 YP_543167.1 CDS UTI89_C4208 NC_007946.1 4095997 4097550 R transcriptional antiterminator complement(4095997..4097550) Escherichia coli UTI89 3991485 YP_543168.1 CDS yicI NC_007946.1 4097845 4100163 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI complement(4097845..4100163) Escherichia coli UTI89 3991486 YP_543169.2 CDS yicJ NC_007946.1 4100173 4101555 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4100173..4101555) Escherichia coli UTI89 3991487 YP_543170.1 CDS rhuM NC_007946.1 4101995 4103032 D cytoplasmic protein 4101995..4103032 Escherichia coli UTI89 3991489 YP_543171.1 CDS UTI89_C4213 NC_007946.1 4103240 4103461 D hypothetical protein 4103240..4103461 Escherichia coli UTI89 3991490 YP_543172.1 CDS yicL NC_007946.1 4104213 4105190 D transport protein YicL 4104213..4105190 Escherichia coli UTI89 3991491 YP_543173.1 CDS nlpA NC_007946.1 4105194 4106012 R cytoplasmic membrane lipoprotein-28 complement(4105194..4106012) Escherichia coli UTI89 3991492 YP_543174.1 CDS UTI89_C4216 NC_007946.1 4106009 4106152 R hypothetical protein complement(4106009..4106152) Escherichia coli UTI89 3991493 YP_543175.1 CDS UTI89_C4217 NC_007946.1 4106165 4106527 D hypothetical protein 4106165..4106527 Escherichia coli UTI89 3991494 YP_543176.2 CDS nepI NC_007946.1 4106568 4107758 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4106568..4107758) Escherichia coli UTI89 3991495 YP_543177.1 CDS yicN NC_007946.1 4107969 4108448 R hypothetical protein complement(4107969..4108448) Escherichia coli UTI89 3991496 YP_543178.1 CDS yicO NC_007946.1 4108474 4109886 R hypothetical protein complement(4108474..4109886) Escherichia coli UTI89 3991497 YP_543179.1 CDS yicP NC_007946.1 4109983 4111749 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4109983..4111749 Escherichia coli UTI89 3991498 YP_543180.1 CDS uhpT NC_007946.1 4111796 4113187 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4111796..4113187) Escherichia coli UTI89 3989920 YP_543181.1 CDS uhpC NC_007946.1 4113325 4114647 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4113325..4114647) Escherichia coli UTI89 3989921 YP_543182.1 CDS uhpB NC_007946.1 4114654 4116156 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4114654..4116156) Escherichia coli UTI89 3989922 YP_543183.1 CDS uhpA NC_007946.1 4116156 4116746 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4116156..4116746) Escherichia coli UTI89 3989923 YP_543184.1 CDS ilvN NC_007946.1 4116819 4117109 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4116819..4117109) Escherichia coli UTI89 3989924 YP_543185.1 CDS ilvB NC_007946.1 4117113 4118801 R acetolactate synthase catalytic subunit complement(4117113..4118801) Escherichia coli UTI89 3989925 YP_543186.1 CDS UTI89_C4228 NC_007946.1 4118785 4119117 D hypothetical protein 4118785..4119117 Escherichia coli UTI89 3989926 YP_543187.1 CDS emrD NC_007946.1 4119400 4120590 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4119400..4120590 Escherichia coli UTI89 3989927 YP_543188.1 CDS yidF NC_007946.1 4120598 4121095 R hypothetical protein complement(4120598..4121095) Escherichia coli UTI89 3989928 YP_543189.1 CDS yidG NC_007946.1 4121092 4121454 R hypothetical protein complement(4121092..4121454) Escherichia coli UTI89 3989929 YP_543190.1 CDS yidH NC_007946.1 4121444 4121851 R hypothetical protein complement(4121444..4121851) Escherichia coli UTI89 3989930 YP_543191.1 CDS yidK NC_007946.1 4123340 4125055 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4123340..4125055) Escherichia coli UTI89 3989931 YP_543192.1 CDS yidL NC_007946.1 4125192 4126088 D transcriptional regulator YidL 4125192..4126088 Escherichia coli UTI89 3989932 YP_543193.1 CDS yidE NC_007946.1 4126178 4127863 R hypothetical protein complement(4126178..4127863) Escherichia coli UTI89 3989933 YP_543194.1 CDS UTI89_C4236 NC_007946.1 4127869 4128039 D hypothetical protein 4127869..4128039 Escherichia coli UTI89 3989934 YP_543195.2 CDS ibpB NC_007946.1 4128036 4128464 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4128036..4128464) Escherichia coli UTI89 3989935 YP_543196.1 CDS ibpA NC_007946.1 4128576 4128995 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4128576..4128995) Escherichia coli UTI89 3989936 YP_543197.2 CDS yidQ NC_007946.1 4129295 4129627 D hypothetical protein 4129295..4129627 Escherichia coli UTI89 3989937 YP_543198.1 CDS yidR NC_007946.1 4129631 4130881 R hypothetical protein complement(4129631..4130881) Escherichia coli UTI89 3989938 YP_543199.2 CDS yidS NC_007946.1 4130946 4132046 D FAD/NAD(P)-binding domain; oxidoreductase 4130946..4132046 Escherichia coli UTI89 3989939 YP_543200.1 CDS dgoT NC_007946.1 4132007 4133344 R D-galactonate transporter complement(4132007..4133344) Escherichia coli UTI89 3992796 YP_543201.1 CDS dgoA NC_007946.1 4133419 4134567 R galactonate dehydratase complement(4133419..4134567) Escherichia coli UTI89 3992797 YP_543202.1 CDS UTI89_C4244 NC_007946.1 4134564 4135181 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4134564..4135181) Escherichia coli UTI89 3992798 YP_543203.1 CDS dgoK NC_007946.1 4135165 4136043 R 2-dehydro-3-deoxygalactonokinase complement(4135165..4136043) Escherichia coli UTI89 3992799 YP_543204.1 CDS dgoR NC_007946.1 4136040 4136729 R galactonate operon transcriptional repressor complement(4136040..4136729) Escherichia coli UTI89 3992800 YP_543205.1 CDS yidA NC_007946.1 4137708 4138520 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4137708..4138520) Escherichia coli UTI89 3992801 YP_543206.1 CDS yidB NC_007946.1 4138635 4139042 R hypothetical protein complement(4138635..4139042) Escherichia coli UTI89 3992802 YP_543207.1 CDS gyrB NC_007946.1 4139273 4141690 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4139273..4141690) Escherichia coli UTI89 3992803 YP_543208.1 CDS recF NC_007946.1 4141716 4142789 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4141716..4142789) Escherichia coli UTI89 3992804 YP_543209.1 CDS dnaN NC_007946.1 4142789 4143889 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4142789..4143889) Escherichia coli UTI89 3992805 YP_543210.1 CDS dnaA NC_007946.1 4143894 4145297 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA complement(4143894..4145297) Escherichia coli UTI89 3992806 YP_543211.1 CDS UTI89_C4253 NC_007946.1 4145591 4145791 R hypothetical protein complement(4145591..4145791) Escherichia coli UTI89 3992807 YP_543212.1 CDS rpmH NC_007946.1 4145904 4146044 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4145904..4146044 Escherichia coli UTI89 3992808 YP_543213.1 CDS rnpA NC_007946.1 4146061 4146420 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4146061..4146420 Escherichia coli UTI89 3992809 YP_543214.1 CDS UTI89_C4256 NC_007946.1 4146108 4146443 R hypothetical protein complement(4146108..4146443) Escherichia coli UTI89 3992810 YP_543215.1 CDS yidD NC_007946.1 4146384 4146641 D hypothetical protein 4146384..4146641 Escherichia coli UTI89 3992811 YP_543216.1 CDS yidC NC_007946.1 4146644 4148290 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4146644..4148290 Escherichia coli UTI89 3992812 YP_543217.1 CDS trmE NC_007946.1 4148396 4149760 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4148396..4149760 Escherichia coli UTI89 3992813 YP_543218.1 CDS tnaL NC_007946.1 4150002 4150076 D tryptophanase 4150002..4150076 Escherichia coli UTI89 3992814 YP_543219.1 CDS tnaA NC_007946.1 4150282 4151712 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4150282..4151712 Escherichia coli UTI89 3994607 YP_543220.1 CDS tnaB NC_007946.1 4151804 4153051 D tryptophan transporter of low affinity; tryptophan permease 4151804..4153051 Escherichia coli UTI89 3994608 YP_543221.1 CDS yidY NC_007946.1 4153183 4154358 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4153183..4154358 Escherichia coli UTI89 3994609 YP_543222.1 CDS yidZ NC_007946.1 4154324 4155292 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4154324..4155292 Escherichia coli UTI89 3994610 YP_543223.1 CDS yieE NC_007946.1 4155437 4156198 D hypothetical protein 4155437..4156198 Escherichia coli UTI89 3994611 YP_543224.1 CDS yieF NC_007946.1 4156220 4156786 D hypothetical protein 4156220..4156786 Escherichia coli UTI89 3994612 YP_543225.1 CDS yieG NC_007946.1 4156839 4158176 R membrane/transport protein complement(4156839..4158176) Escherichia coli UTI89 3994613 YP_543226.1 CDS yieI NC_007946.1 4159080 4159553 D might be involved in hypersensitivity to nitrofurzone; hypothetical protein 4159080..4159553 Escherichia coli UTI89 3994614 YP_543227.1 CDS yieK NC_007946.1 4159635 4160357 R 6-phosphogluconolactonase complement(4159635..4160357) Escherichia coli UTI89 3994615 YP_543228.1 CDS yieL NC_007946.1 4160372 4161574 R xylanase complement(4160372..4161574) Escherichia coli UTI89 3994616 YP_543229.1 CDS yieC NC_007946.1 4161568 4163184 R outer membrane protein YieC complement(4161568..4163184) Escherichia coli UTI89 3994617 YP_543230.1 CDS bglB NC_007946.1 4163270 4164664 R 6-phospho-beta-glucosidase complement(4163270..4164664) Escherichia coli UTI89 3994618 YP_543231.1 CDS bglF NC_007946.1 4164683 4166632 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunits IIABC complement(4164683..4166632) Escherichia coli UTI89 3994619 YP_543232.1 CDS bglG NC_007946.1 4166691 4167551 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4166691..4167551) Escherichia coli UTI89 3994620 YP_543233.1 CDS UTI89_C4275 NC_007946.1 4167593 4167715 D hypothetical protein 4167593..4167715 Escherichia coli UTI89 3994621 YP_543234.2 CDS phoU NC_007946.1 4167813 4168538 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4167813..4168538) Escherichia coli UTI89 3994622 YP_543235.1 CDS pstB NC_007946.1 4168553 4169326 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4168553..4169326) Escherichia coli UTI89 3994623 YP_543236.1 CDS pstA NC_007946.1 4169417 4170307 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4169417..4170307) Escherichia coli UTI89 3994624 YP_543237.1 CDS pstC NC_007946.1 4170307 4171266 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4170307..4171266) Escherichia coli UTI89 3994625 YP_543238.1 CDS pstS NC_007946.1 4171353 4172393 R phosphate ABC transporter periplasmic substrate-binding protein PstS complement(4171353..4172393) Escherichia coli UTI89 3994626 YP_543239.1 CDS glmS NC_007946.1 4172707 4174536 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4172707..4174536) Escherichia coli UTI89 3994403 YP_543240.1 CDS glmU NC_007946.1 4174697 4176067 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4174697..4176067) Escherichia coli UTI89 3994404 YP_543241.1 CDS UTI89_C4283 NC_007946.1 4176337 4176864 D hypothetical protein 4176337..4176864 Escherichia coli UTI89 3994405 YP_543242.1 CDS atpC NC_007946.1 4176421 4176840 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(4176421..4176840) Escherichia coli UTI89 3994406 YP_543243.1 CDS atpD NC_007946.1 4176861 4178243 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(4176861..4178243) Escherichia coli UTI89 3994407 YP_543244.1 CDS atpG NC_007946.1 4178270 4179133 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(4178270..4179133) Escherichia coli UTI89 3994408 YP_543245.1 CDS atpA NC_007946.1 4179184 4180725 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(4179184..4180725) Escherichia coli UTI89 3994409 YP_543246.1 CDS UTI89_C4288 NC_007946.1 4179193 4180872 D hypothetical protein 4179193..4180872 Escherichia coli UTI89 3994410 YP_543247.1 CDS atpH NC_007946.1 4180738 4181271 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(4180738..4181271) Escherichia coli UTI89 3994411 YP_543248.1 CDS UTI89_C4290 NC_007946.1 4180912 4181649 D hypothetical protein 4180912..4181649 Escherichia coli UTI89 3994412 YP_543249.1 CDS atpF NC_007946.1 4181286 4181756 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(4181286..4181756) Escherichia coli UTI89 3994413 YP_543250.1 CDS atpE NC_007946.1 4181818 4182057 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(4181818..4182057) Escherichia coli UTI89 3994414 YP_543251.1 CDS atpB NC_007946.1 4182104 4182919 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(4182104..4182919) Escherichia coli UTI89 3994415 YP_543252.1 CDS atpI NC_007946.1 4182928 4183320 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4182928..4183320) Escherichia coli UTI89 3994416 YP_543253.1 CDS gidB NC_007946.1 4183925 4184548 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4183925..4184548) Escherichia coli UTI89 3994417 YP_543254.1 CDS gidA NC_007946.1 4184612 4186501 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(4184612..4186501) Escherichia coli UTI89 3994418 YP_543255.1 CDS mioC NC_007946.1 4186880 4187323 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4186880..4187323) Escherichia coli UTI89 3994419 YP_543256.1 CDS asnC NC_007946.1 4187413 4187871 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4187413..4187871) Escherichia coli UTI89 3994420 YP_543257.1 CDS asnA NC_007946.1 4188023 4189015 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4188023..4189015 Escherichia coli UTI89 3994421 YP_543258.1 CDS yieM NC_007946.1 4189020 4190471 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4189020..4190471) Escherichia coli UTI89 3994312 YP_543259.1 CDS yieN NC_007946.1 4190465 4191985 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4190465..4191985) Escherichia coli UTI89 3994313 YP_543260.1 CDS trkD NC_007946.1 4192184 4194052 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4192184..4194052 Escherichia coli UTI89 3994314 YP_543261.1 CDS rbsD NC_007946.1 4194207 4194638 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4194207..4194638 Escherichia coli UTI89 3994315 YP_543262.1 CDS rbsA NC_007946.1 4194646 4196151 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4194646..4196151 Escherichia coli UTI89 3994316 YP_543263.1 CDS rbsC NC_007946.1 4196156 4197121 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4196156..4197121 Escherichia coli UTI89 3994317 YP_543264.1 CDS rbsB NC_007946.1 4197140 4198036 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4197140..4198036 Escherichia coli UTI89 3994318 YP_543265.2 CDS rbsK NC_007946.1 4198147 4199091 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4198147..4199091 Escherichia coli UTI89 3994319 YP_543266.1 CDS rbsR NC_007946.1 4199095 4200087 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4199095..4200087 Escherichia coli UTI89 3994320 YP_543267.1 CDS yieO NC_007946.1 4200053 4201480 R transport protein YieO complement(4200053..4201480) Escherichia coli UTI89 3994321 YP_543268.1 CDS yieP NC_007946.1 4201503 4202195 R transcriptional regulator YieP complement(4201503..4202195) Escherichia coli UTI89 3994322 YP_543272.1 CDS hdfR NC_007946.1 4207996 4208835 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4207996..4208835) Escherichia coli UTI89 3994027 YP_543273.1 CDS yifE NC_007946.1 4208954 4209292 D hypothetical protein 4208954..4209292 Escherichia coli UTI89 3994028 YP_543274.1 CDS yifB NC_007946.1 4209317 4210867 R among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4209317..4210867) Escherichia coli UTI89 3994029 YP_543275.1 CDS UTI89_C4323 NC_007946.1 4210858 4211043 R hypothetical protein complement(4210858..4211043) Escherichia coli UTI89 3994030 YP_543276.1 CDS ilvG NC_007946.1 4211428 4213074 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4211428..4213074 Escherichia coli UTI89 3994031 YP_543277.1 CDS ilvM NC_007946.1 4213071 4213334 D acetolactate synthase 2 regulatory subunit 4213071..4213334 Escherichia coli UTI89 3994032 YP_543278.1 CDS ilvE NC_007946.1 4213354 4214283 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4213354..4214283 Escherichia coli UTI89 3994033 YP_543279.1 CDS ilvD NC_007946.1 4214348 4216198 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4214348..4216198 Escherichia coli UTI89 3994034 YP_543280.1 CDS ilvA NC_007946.1 4216198 4217745 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4216198..4217745 Escherichia coli UTI89 3994035 YP_543281.2 CDS ilvY NC_007946.1 4217742 4218632 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4217742..4218632) Escherichia coli UTI89 3994036 YP_543282.1 CDS ilvC NC_007946.1 4218632 4220257 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4218632..4220257 Escherichia coli UTI89 3994037 YP_543283.1 CDS ppiC NC_007946.1 4220303 4220584 R peptidyl-prolyl cis-trans isomerase C complement(4220303..4220584) Escherichia coli UTI89 3994038 YP_543284.1 CDS rep NC_007946.1 4220671 4222692 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4220671..4222692 Escherichia coli UTI89 3994039 YP_543285.1 CDS gppA NC_007946.1 4222739 4224232 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4222739..4224232) Escherichia coli UTI89 3993312 YP_543286.1 CDS rhlB NC_007946.1 4224359 4225624 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4224359..4225624) Escherichia coli UTI89 3993313 YP_543287.1 CDS trxA NC_007946.1 4225650 4226084 D thioredoxin 4225650..4226084 Escherichia coli UTI89 3993314 YP_543288.1 CDS UTI89_C4336 NC_007946.1 4225749 4226141 R hypothetical protein complement(4225749..4226141) Escherichia coli UTI89 3993315 YP_543289.1 CDS rhoL NC_007946.1 4226225 4226326 D rho operon leader peptide 4226225..4226326 Escherichia coli UTI89 3993316 YP_543290.1 CDS rho NC_007946.1 4226339 4227670 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4226339..4227670 Escherichia coli UTI89 3993317 YP_543291.1 CDS UTI89_C4339 NC_007946.1 4227680 4227805 D hypothetical protein 4227680..4227805 Escherichia coli UTI89 3993318 YP_543292.1 CDS rfe NC_007946.1 4227910 4229013 D undecaprenyl-phosphate alpha-N-acetylglucosaminyl transferase 4227910..4229013 Escherichia coli UTI89 3993319 YP_543293.1 CDS wzzE NC_007946.1 4229022 4230071 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4229022..4230071 Escherichia coli UTI89 3993320 YP_543294.1 CDS rffE NC_007946.1 4230085 4231257 D synonym: yifF, b3786, G7969, nfrC, wecB; UDP-N-acetylglucosamine 2-epimerase 4230085..4231257 Escherichia coli UTI89 3993321 YP_543295.1 CDS wecC NC_007946.1 4231254 4232516 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4231254..4232516 Escherichia coli UTI89 3993322 YP_543296.1 CDS rffG NC_007946.1 4232516 4233583 D synonym: rff, b3788, nfrC, rffE; dTDP-glucose 4,6-dehydratase 4232516..4233583 Escherichia coli UTI89 3993323 YP_543297.1 CDS rffH NC_007946.1 4233602 4234483 D synonym: b3789, yifG; glucose-1-phosphate thymidylyltransferase 4233602..4234483 Escherichia coli UTI89 3993324 YP_543298.1 CDS rffC NC_007946.1 4234461 4235135 D synonym: rff, b3790, wecD, yifH; TDP-fucosamine acetyltransferase 4234461..4235135 Escherichia coli UTI89 3993325 YP_543299.1 CDS rffA NC_007946.1 4235140 4236270 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4235140..4236270 Escherichia coli UTI89 3993326 YP_543300.1 CDS UTI89_C4348 NC_007946.1 4235287 4236321 R hypothetical protein complement(4235287..4236321) Escherichia coli UTI89 3993327 YP_543301.1 CDS wzxE NC_007946.1 4236272 4237522 D cytochrome 4236272..4237522 Escherichia coli UTI89 3993328 YP_543302.1 CDS UTI89_C4350 NC_007946.1 4237519 4238598 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4237519..4238598 Escherichia coli UTI89 3993329 YP_543303.1 CDS wzyE NC_007946.1 4238595 4239947 D enterobacterial common antigen polymerase; common antigen polymerase 4238595..4239947 Escherichia coli UTI89 3993330 YP_543304.1 CDS rffM NC_007946.1 4239950 4240690 D synonym: rff, b3794, wecG; UDP-N-acetyl-D-mannosaminuronic acid transferase 4239950..4240690 Escherichia coli UTI89 3993331 YP_543305.1 CDS yifK NC_007946.1 4240881 4242266 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4240881..4242266 Escherichia coli UTI89 3992509 YP_543306.1 CDS aslB NC_007946.1 4242922 4244187 D arylsulfatase 4242922..4244187 Escherichia coli UTI89 3992514 YP_543307.1 CDS aslA NC_007946.1 4244345 4246000 R arylsulfatase complement(4244345..4246000) Escherichia coli UTI89 3992515 YP_543308.1 CDS UTI89_C4360 NC_007946.1 4245897 4246052 D hypothetical protein 4245897..4246052 Escherichia coli UTI89 3992516 YP_543309.1 CDS hemY NC_007946.1 4246679 4247875 R protoheme IX biogenesis protein complement(4246679..4247875) Escherichia coli UTI89 3992517 YP_543310.1 CDS hemX NC_007946.1 4247878 4249077 R uroporphyrinogen III C-methyltransferase complement(4247878..4249077) Escherichia coli UTI89 3992518 YP_543311.1 CDS hemD NC_007946.1 4249099 4249839 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4249099..4249839) Escherichia coli UTI89 3992519 YP_543312.1 CDS hemC NC_007946.1 4249836 4250798 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4249836..4250798) Escherichia coli UTI89 3992520 YP_543313.1 CDS cyaA NC_007946.1 4251164 4253710 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4251164..4253710 Escherichia coli UTI89 3992521 YP_543314.1 CDS cyaY NC_007946.1 4253750 4254070 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4253750..4254070) Escherichia coli UTI89 3992522 YP_543315.1 CDS UTI89_C4367 NC_007946.1 4254118 4255434 R hypothetical protein complement(4254118..4255434) Escherichia coli UTI89 3992523 YP_543316.1 CDS UTI89_C4368 NC_007946.1 4255566 4255778 D hypothetical protein 4255566..4255778 Escherichia coli UTI89 3992581 YP_543317.1 CDS insB2 NC_007946.1 4255789 4256292 D IS1 protein InsB 4255789..4256292 Escherichia coli UTI89 3992582 YP_543318.1 CDS UTI89_C4370 NC_007946.1 4256303 4257706 R hypothetical protein complement(4256303..4257706) Escherichia coli UTI89 3992583 YP_543319.1 CDS yifL NC_007946.1 4257865 4258068 D lipoprotein 4257865..4258068 Escherichia coli UTI89 3992584 YP_543320.1 CDS dapF NC_007946.1 4258102 4258929 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4258102..4258929 Escherichia coli UTI89 3992585 YP_543321.1 CDS yigA NC_007946.1 4258926 4259633 D hypothetical protein 4258926..4259633 Escherichia coli UTI89 3992586 YP_543322.1 CDS xerC NC_007946.1 4259630 4260526 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4259630..4260526 Escherichia coli UTI89 3992587 YP_543323.1 CDS yigB NC_007946.1 4260526 4261242 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4260526..4261242 Escherichia coli UTI89 3992588 YP_543324.2 CDS uvrD NC_007946.1 4261326 4263488 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4261326..4263488 Escherichia coli UTI89 3992589 YP_543325.1 CDS UTI89_C4377 NC_007946.1 4263533 4264435 R hypothetical protein complement(4263533..4264435) Escherichia coli UTI89 3992590 YP_543326.1 CDS UTI89_C4378 NC_007946.1 4264518 4265282 R hypothetical protein complement(4264518..4265282) Escherichia coli UTI89 3992591 YP_543327.2 CDS corA NC_007946.1 4265652 4266602 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4265652..4266602 Escherichia coli UTI89 3992592 YP_543328.1 CDS UTI89_C4380 NC_007946.1 4266638 4267135 R hypothetical protein complement(4266638..4267135) Escherichia coli UTI89 3992593 YP_543329.1 CDS UTI89_C4381 NC_007946.1 4267132 4267980 R hypothetical protein complement(4267132..4267980) Escherichia coli UTI89 3992594 YP_543330.1 CDS rarD NC_007946.1 4268291 4269181 R hypothetical protein complement(4268291..4269181) Escherichia coli UTI89 3992595 YP_543331.2 CDS yigI NC_007946.1 4269233 4269700 R hypothetical protein complement(4269233..4269700) Escherichia coli UTI89 3992596 YP_543332.1 CDS pldA NC_007946.1 4269865 4270734 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4269865..4270734 Escherichia coli UTI89 3992597 YP_543333.1 CDS UTI89_C4385 NC_007946.1 4270738 4270899 D hypothetical protein 4270738..4270899 Escherichia coli UTI89 3992598 YP_543334.1 CDS recQ NC_007946.1 4270853 4272688 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4270853..4272688 Escherichia coli UTI89 3992599 YP_543335.1 CDS UTI89_C4387 NC_007946.1 4272752 4273372 D threonine efflux system 4272752..4273372 Escherichia coli UTI89 3994647 YP_543336.1 CDS rhtB NC_007946.1 4273433 4274053 R synonym: b3824, yigK; homoserine/homoserine lactone efflux protein complement(4273433..4274053) Escherichia coli UTI89 3994648 YP_543337.1 CDS pldB NC_007946.1 4274164 4275186 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4274164..4275186 Escherichia coli UTI89 3994649 YP_543338.1 CDS UTI89_C4390 NC_007946.1 4275131 4275994 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4275131..4275994 Escherichia coli UTI89 3994650 YP_543339.1 CDS yigM NC_007946.1 4276070 4276969 D hypothetical protein 4276070..4276969 Escherichia coli UTI89 3994651 YP_543340.1 CDS metR NC_007946.1 4276857 4277810 R regulator for metE and MetH complement(4276857..4277810) Escherichia coli UTI89 3994652 YP_543341.1 CDS metE NC_007946.1 4277928 4280189 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4277928..4280189 Escherichia coli UTI89 3994653 YP_543342.1 CDS UTI89_C4394 NC_007946.1 4280196 4280321 R hypothetical protein complement(4280196..4280321) Escherichia coli UTI89 3994654 YP_543343.1 CDS UTI89_C4395 NC_007946.1 4280358 4280618 R hypothetical protein complement(4280358..4280618) Escherichia coli UTI89 3994655 YP_543344.1 CDS UTI89_C4396 NC_007946.1 4280678 4280935 R hypothetical protein complement(4280678..4280935) Escherichia coli UTI89 3994656 YP_543345.1 CDS UTI89_C4397 NC_007946.1 4280932 4281621 R hypothetical protein complement(4280932..4281621) Escherichia coli UTI89 3994657 YP_543346.1 CDS UTI89_C4398 NC_007946.1 4282538 4283107 D hypothetical protein 4282538..4283107 Escherichia coli UTI89 3994658 YP_543347.1 CDS UTI89_C4399 NC_007946.1 4283149 4284657 D PTS system glucose-specific transporter subunit IIBC 4283149..4284657 Escherichia coli UTI89 3994659 YP_543348.1 CDS UTI89_C4400 NC_007946.1 4284708 4286705 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4284708..4286705 Escherichia coli UTI89 3994660 YP_543349.1 CDS UTI89_C4401 NC_007946.1 4286735 4287580 R hypothetical protein complement(4286735..4287580) Escherichia coli UTI89 3994661 YP_543350.1 CDS UTI89_C4402 NC_007946.1 4287781 4288686 R hypothetical protein complement(4287781..4288686) Escherichia coli UTI89 3994662 YP_543351.1 CDS UTI89_C4403 NC_007946.1 4288764 4289987 R permease complement(4288764..4289987) Escherichia coli UTI89 3994663 YP_543352.1 CDS UTI89_C4404 NC_007946.1 4290013 4290402 R hypothetical protein complement(4290013..4290402) Escherichia coli UTI89 3994664 YP_543353.1 CDS UTI89_C4405 NC_007946.1 4290419 4291375 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4290419..4291375) Escherichia coli UTI89 3994665 YP_543354.1 CDS UTI89_C4406 NC_007946.1 4291368 4292843 R hypothetical protein complement(4291368..4292843) Escherichia coli UTI89 3994666 YP_543355.1 CDS UTI89_C4407 NC_007946.1 4292789 4294348 R hypothetical protein complement(4292789..4294348) Escherichia coli UTI89 3993351 YP_543356.1 CDS UTI89_C4408 NC_007946.1 4294443 4295303 R hypothetical protein complement(4294443..4295303) Escherichia coli UTI89 3993352 YP_543357.1 CDS UTI89_C4409 NC_007946.1 4295309 4295908 R hypothetical protein complement(4295309..4295908) Escherichia coli UTI89 3993353 YP_543358.1 CDS UTI89_C4410 NC_007946.1 4296234 4297109 R carboxymethylenebutenolidase complement(4296234..4297109) Escherichia coli UTI89 3993354 YP_543359.2 CDS udp NC_007946.1 4297305 4298069 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4297305..4298069 Escherichia coli UTI89 3993355 YP_543360.1 CDS UTI89_C4412 NC_007946.1 4298104 4299594 R hypothetical protein complement(4298104..4299594) Escherichia coli UTI89 3993356 YP_543361.1 CDS UTI89_C4413 NC_007946.1 4299607 4300116 R hypothetical protein complement(4299607..4300116) Escherichia coli UTI89 3993357 YP_543362.1 CDS UTI89_C4414 NC_007946.1 4300130 4301104 R hypothetical protein complement(4300130..4301104) Escherichia coli UTI89 3993358 YP_543363.1 CDS UTI89_C4415 NC_007946.1 4301129 4301758 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4301129..4301758) Escherichia coli UTI89 3993359 YP_543364.1 CDS UTI89_C4416 NC_007946.1 4301748 4302752 R hypothetical protein complement(4301748..4302752) Escherichia coli UTI89 3993360 YP_543365.1 CDS UTI89_C4417 NC_007946.1 4302776 4303630 R transcriptional regulator complement(4302776..4303630) Escherichia coli UTI89 3993361 YP_543366.1 CDS UTI89_C4418 NC_007946.1 4303707 4303865 D hypothetical protein 4303707..4303865 Escherichia coli UTI89 3993362 YP_543367.1 CDS rmuC NC_007946.1 4303760 4305187 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4303760..4305187 Escherichia coli UTI89 3993363 YP_543368.1 CDS ubiE NC_007946.1 4305282 4306037 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4305282..4306037 Escherichia coli UTI89 3993364 YP_543369.1 CDS yigP NC_007946.1 4306006 4306656 D hypothetical protein 4306006..4306656 Escherichia coli UTI89 3993365 YP_543370.1 CDS ubiB NC_007946.1 4306653 4308293 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4306653..4308293 Escherichia coli UTI89 3993366 YP_543371.1 CDS tatA NC_007946.1 4308330 4308641 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin-arginine translocation protein TatA 4308330..4308641 Escherichia coli UTI89 3993367 YP_543372.1 CDS tatB NC_007946.1 4308645 4309160 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4308645..4309160 Escherichia coli UTI89 3993368 YP_543373.1 CDS tatC NC_007946.1 4309163 4309939 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4309163..4309939 Escherichia coli UTI89 3993369 YP_543374.1 CDS tatD NC_007946.1 4309969 4310763 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4309969..4310763 Escherichia coli UTI89 3993832 YP_543375.1 CDS rfaH NC_007946.1 4310760 4311248 R transcriptional activator RfaH complement(4310760..4311248) Escherichia coli UTI89 3993833 YP_543376.1 CDS yigC NC_007946.1 4311415 4312908 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4311415..4312908 Escherichia coli UTI89 3993834 YP_543377.1 CDS fre NC_007946.1 4312921 4313655 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4312921..4313655 Escherichia coli UTI89 3993835 YP_543378.1 CDS fadA NC_007946.1 4313938 4315101 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4313938..4315101) Escherichia coli UTI89 3993836 YP_543379.2 CDS fadB NC_007946.1 4315111 4317300 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4315111..4317300) Escherichia coli UTI89 3993837 YP_543380.1 CDS pepQ NC_007946.1 4317490 4318821 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4317490..4318821 Escherichia coli UTI89 3993838 YP_543381.1 CDS yigZ NC_007946.1 4318818 4319435 D hypothetical protein 4318818..4319435 Escherichia coli UTI89 3993839 YP_543382.1 CDS trkH NC_007946.1 4319474 4320925 D potassium transporter 4319474..4320925 Escherichia coli UTI89 3993840 YP_543383.1 CDS hemG NC_007946.1 4320937 4321482 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4320937..4321482 Escherichia coli UTI89 3993841 YP_543386.1 CDS mobB NC_007946.1 4327063 4327590 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4327063..4327590) Escherichia coli UTI89 3992601 YP_543387.1 CDS mobA NC_007946.1 4327572 4328156 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4327572..4328156) Escherichia coli UTI89 3992602 YP_543388.1 CDS yihD NC_007946.1 4328196 4328495 D hypothetical protein 4328196..4328495 Escherichia coli UTI89 3992603 YP_543389.1 CDS rdoA NC_007946.1 4328572 4329558 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4328572..4329558 Escherichia coli UTI89 3992604 YP_543390.1 CDS dsbA NC_007946.1 4329575 4330201 D periplasmic protein disulfide isomerase I 4329575..4330201 Escherichia coli UTI89 3992605 YP_543391.1 CDS UTI89_C4448 NC_007946.1 4330226 4330366 D hypothetical protein 4330226..4330366 Escherichia coli UTI89 3992606 YP_543392.1 CDS yihF NC_007946.1 4330314 4331786 D hypothetical protein 4330314..4331786 Escherichia coli UTI89 3992607 YP_543393.1 CDS yihG NC_007946.1 4331827 4332783 R acyltransferase complement(4331827..4332783) Escherichia coli UTI89 3992608 YP_543394.1 CDS UTI89_C4451 NC_007946.1 4332879 4333121 R hypothetical protein complement(4332879..4333121) Escherichia coli UTI89 3992609 YP_543395.1 CDS polA NC_007946.1 4333123 4335909 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4333123..4335909 Escherichia coli UTI89 3992610 YP_543396.1 CDS UTI89_C4453 NC_007946.1 4336128 4336277 R hypothetical protein complement(4336128..4336277) Escherichia coli UTI89 3992611 YP_543397.2 CDS engB NC_007946.1 4336291 4336923 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4336291..4336923) Escherichia coli UTI89 3992612 YP_543398.1 CDS yihI NC_007946.1 4337505 4338014 D hypothetical protein 4337505..4338014 Escherichia coli UTI89 3992613 YP_543399.1 CDS hemN NC_007946.1 4338197 4339576 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4338197..4339576 Escherichia coli UTI89 3992614 YP_543400.2 CDS glnG NC_007946.1 4339936 4341345 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4339936..4341345) Escherichia coli UTI89 3992615 YP_543401.1 CDS glnL NC_007946.1 4341357 4342406 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4341357..4342406) Escherichia coli UTI89 3992616 YP_543402.1 CDS glnA NC_007946.1 4342580 4343989 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4342580..4343989) Escherichia coli UTI89 3992617 YP_543403.1 CDS typA NC_007946.1 4344362 4346185 D synonym: b3871, bipA, yihK, yjhK; GTP-binding protein 4344362..4346185 Escherichia coli UTI89 3992430 YP_543404.1 CDS yihW NC_007946.1 4346292 4347080 R transcriptional regulator YihW complement(4346292..4347080) Escherichia coli UTI89 3992431 YP_543405.1 CDS yihV NC_007946.1 4347120 4348067 R sugar kinase YihV complement(4347120..4348067) Escherichia coli UTI89 3992432 YP_543406.1 CDS yihU NC_007946.1 4348188 4349066 D oxidoreductase YihU 4348188..4349066 Escherichia coli UTI89 3992433 YP_543407.1 CDS yihT NC_007946.1 4349091 4349978 D hypothetical protein 4349091..4349978 Escherichia coli UTI89 3992434 YP_543408.1 CDS UTI89_C4465 NC_007946.1 4350011 4351021 D dehydrogenase 4350011..4351021 Escherichia coli UTI89 3992435 YP_543409.1 CDS UTI89_C4466 NC_007946.1 4351091 4352524 D hypothetical protein 4351091..4352524 Escherichia coli UTI89 3992436 YP_543410.1 CDS UTI89_C4467 NC_007946.1 4352623 4353972 D shikimate transporter 4352623..4353972 Escherichia coli UTI89 3992437 YP_543411.1 CDS UTI89_C4468 NC_007946.1 4353905 4354849 D hypothetical protein 4353905..4354849 Escherichia coli UTI89 3992438 YP_543412.1 CDS yihX NC_007946.1 4354969 4355589 D phosphatase 4354969..4355589 Escherichia coli UTI89 3992439 YP_543413.1 CDS rbn NC_007946.1 4355583 4356455 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4355583..4356455 Escherichia coli UTI89 3992440 YP_543414.1 CDS yihZ NC_007946.1 4356452 4356889 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4356452..4356889 Escherichia coli UTI89 3992441 YP_543415.1 CDS yiiD NC_007946.1 4356886 4357875 D acetyltransferase 4356886..4357875 Escherichia coli UTI89 3992442 YP_543416.1 CDS UTI89_C4473 NC_007946.1 4357939 4358859 R lipase complement(4357939..4358859) Escherichia coli UTI89 3992443 YP_543417.1 CDS UTI89_C4474 NC_007946.1 4359076 4359387 D hypothetical protein 4359076..4359387 Escherichia coli UTI89 3992444 YP_543418.1 CDS UTI89_C4475 NC_007946.1 4359388 4359678 D hypothetical protein 4359388..4359678 Escherichia coli UTI89 3992445 YP_543419.1 CDS UTI89_C4476 NC_007946.1 4360037 4360315 D hypothetical protein 4360037..4360315 Escherichia coli UTI89 3992446 YP_543420.1 CDS yiiE NC_007946.1 4360684 4360929 D hypothetical protein 4360684..4360929 Escherichia coli UTI89 3992447 YP_543421.1 CDS fdhE NC_007946.1 4361145 4362074 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4361145..4362074) Escherichia coli UTI89 3992448 YP_543422.1 CDS fdoI NC_007946.1 4362071 4362706 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4362071..4362706) Escherichia coli UTI89 3992449 YP_543423.1 CDS fdoH NC_007946.1 4362703 4363605 R formate dehydrogenase-O, iron-sulfur subunit complement(4362703..4363605) Escherichia coli UTI89 3992411 YP_543424.1 CDS UTI89_C4481 NC_007946.1 4366300 4366926 D hypothetical protein 4366300..4366926 Escherichia coli UTI89 3992412 YP_543425.1 CDS fdhD NC_007946.1 4366862 4367695 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4366862..4367695 Escherichia coli UTI89 3992413 YP_543426.1 CDS UTI89_C4483 NC_007946.1 4368825 4370219 D glycoporin 4368825..4370219 Escherichia coli UTI89 3992414 YP_543427.1 CDS yiiL NC_007946.1 4370260 4370574 R hypothetical protein complement(4370260..4370574) Escherichia coli UTI89 3992415 YP_543428.1 CDS rhaD NC_007946.1 4370584 4371501 R rhamnulose-1-phosphate aldolase complement(4370584..4371501) Escherichia coli UTI89 3992416 YP_543429.1 CDS rhaA NC_007946.1 4371685 4372950 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4371685..4372950) Escherichia coli UTI89 3992417 YP_543430.1 CDS rhaB NC_007946.1 4372941 4374410 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4372941..4374410) Escherichia coli UTI89 3992418 YP_543431.1 CDS rhaS NC_007946.1 4374698 4375534 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4374698..4375534 Escherichia coli UTI89 3992419 YP_543432.1 CDS rhaR NC_007946.1 4375497 4376456 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4375497..4376456 Escherichia coli UTI89 3992420 YP_543433.1 CDS rhaT NC_007946.1 4376453 4377487 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4376453..4377487) Escherichia coli UTI89 3992421 YP_543434.1 CDS sodA NC_007946.1 4377766 4378392 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4377766..4378392 Escherichia coli UTI89 3992422 YP_543435.1 CDS UTI89_C4492 NC_007946.1 4378421 4378549 R hypothetical protein complement(4378421..4378549) Escherichia coli UTI89 3992423 YP_543436.2 CDS kdgT NC_007946.1 4378652 4379635 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4378652..4379635 Escherichia coli UTI89 3992424 YP_543437.2 CDS yiiM NC_007946.1 4379784 4380458 D hypothetical protein 4379784..4380458 Escherichia coli UTI89 3992425 YP_543438.1 CDS cpxA NC_007946.1 4380564 4381937 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4380564..4381937) Escherichia coli UTI89 3992426 YP_543439.1 CDS cpxR NC_007946.1 4381934 4382632 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4381934..4382632) Escherichia coli UTI89 3992427 YP_543440.2 CDS cpxP NC_007946.1 4382782 4383282 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4382782..4383282 Escherichia coli UTI89 3992428 YP_543441.2 CDS fieF NC_007946.1 4383431 4384333 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4383431..4384333 Escherichia coli UTI89 3992429 YP_543442.1 CDS pfkA NC_007946.1 4384418 4385476 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4384418..4385476 Escherichia coli UTI89 3994174 YP_543443.1 CDS UTI89_C4500 NC_007946.1 4385735 4385872 D hypothetical protein 4385735..4385872 Escherichia coli UTI89 3994175 YP_543444.1 CDS sbp NC_007946.1 4385796 4386785 D sulfate transporter subunit 4385796..4386785 Escherichia coli UTI89 3994176 YP_543445.1 CDS cdh NC_007946.1 4386700 4387647 D CDP-diacylglycerol pyrophosphatase 4386700..4387647 Escherichia coli UTI89 3994177 YP_543446.1 CDS tpiA NC_007946.1 4387702 4388469 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4387702..4388469) Escherichia coli UTI89 3994178 YP_543447.1 CDS yiiQ NC_007946.1 4388577 4389176 R hypothetical protein complement(4388577..4389176) Escherichia coli UTI89 3994179 YP_543448.1 CDS yiiR NC_007946.1 4389277 4389717 D hypothetical protein 4389277..4389717 Escherichia coli UTI89 3994180 YP_543449.1 CDS yiiS NC_007946.1 4389929 4390228 D hypothetical protein 4389929..4390228 Escherichia coli UTI89 3994181 YP_543450.1 CDS yiiT NC_007946.1 4390255 4390683 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4390255..4390683 Escherichia coli UTI89 3994182 YP_543451.1 CDS fpr NC_007946.1 4390688 4391434 R synonym: flxR, b3924, G7964, fruB, mvrA; ferredoxin-NADP reductase complement(4390688..4391434) Escherichia coli UTI89 3994183 YP_543452.1 CDS glpX NC_007946.1 4391531 4392541 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4391531..4392541) Escherichia coli UTI89 3994184 YP_543453.1 CDS glpK NC_007946.1 4392712 4394325 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4392712..4394325) Escherichia coli UTI89 3994185 YP_543454.1 CDS glpF NC_007946.1 4394243 4395088 R glycerol MIP channel complement(4394243..4395088) Escherichia coli UTI89 3994186 YP_543455.1 CDS yiiU NC_007946.1 4395495 4395758 D hypothetical protein 4395495..4395758 Escherichia coli UTI89 3994187 YP_543456.1 CDS menG NC_007946.1 4395843 4396328 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4395843..4396328) Escherichia coli UTI89 3994188 YP_543457.1 CDS UTI89_C4514 NC_007946.1 4395900 4396406 D hypothetical protein 4395900..4396406 Escherichia coli UTI89 3994189 YP_543458.1 CDS menA NC_007946.1 4396421 4397359 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4396421..4397359) Escherichia coli UTI89 3994190 YP_543459.1 CDS hslU NC_007946.1 4397414 4398745 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4397414..4398745) Escherichia coli UTI89 3994191 YP_543460.1 CDS hslV NC_007946.1 4398755 4399285 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4398755..4399285) Escherichia coli UTI89 3994192 YP_543461.1 CDS ftsN NC_007946.1 4399378 4400337 R essential cell division protein FtsN complement(4399378..4400337) Escherichia coli UTI89 3994193 YP_543462.1 CDS cytR NC_007946.1 4400429 4401454 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4400429..4401454) Escherichia coli UTI89 3992562 YP_543463.1 CDS priA NC_007946.1 4401610 4403880 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4401610..4403880) Escherichia coli UTI89 3992563 YP_543464.1 CDS UTI89_C4521 NC_007946.1 4403993 4404133 R hypothetical protein complement(4403993..4404133) Escherichia coli UTI89 3992564 YP_543465.1 CDS yiiX NC_007946.1 4404284 4404892 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4404284..4404892) Escherichia coli UTI89 3992565 YP_543466.1 CDS metJ NC_007946.1 4404952 4405407 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4404952..4405407) Escherichia coli UTI89 3992566 YP_543467.1 CDS metB NC_007946.1 4405432 4406706 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4405432..4406706 Escherichia coli UTI89 3992567 YP_543468.1 CDS metL NC_007946.1 4406709 4409141 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4406709..4409141 Escherichia coli UTI89 3992568 YP_543469.1 CDS UTI89_C4526 NC_007946.1 4409359 4410219 R bifunctional nucleoside and albicidin permease/phage T6 and colicin K receptor complement(4409359..4410219) Escherichia coli UTI89 3992569 YP_543470.1 CDS UTI89_C4527 NC_007946.1 4410296 4411921 R hypothetical protein complement(4410296..4411921) Escherichia coli UTI89 3992570 YP_543471.1 CDS UTI89_C4528 NC_007946.1 4411956 4413509 R hypothetical protein complement(4411956..4413509) Escherichia coli UTI89 3992571 YP_543472.1 CDS UTI89_C4529 NC_007946.1 4413739 4414863 R hypothetical protein complement(4413739..4414863) Escherichia coli UTI89 3992572 YP_543473.1 CDS UTI89_C4530 NC_007946.1 4414990 4416549 D hypothetical protein 4414990..4416549 Escherichia coli UTI89 3992573 YP_543474.1 CDS metF NC_007946.1 4416931 4417821 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4416931..4417821 Escherichia coli UTI89 3992574 YP_543475.1 CDS katG NC_007946.1 4418111 4420330 D bifunctional catalase HPI/peroxidase HPI 4418111..4420330 Escherichia coli UTI89 3992575 YP_543476.1 CDS yijE NC_007946.1 4420358 4421329 D transport protein YijE 4420358..4421329 Escherichia coli UTI89 3992576 YP_543477.1 CDS yijF NC_007946.1 4421356 4421973 R hypothetical protein complement(4421356..4421973) Escherichia coli UTI89 3992577 YP_543478.1 CDS UTI89_C4535 NC_007946.1 4421873 4422067 R hypothetical protein complement(4421873..4422067) Escherichia coli UTI89 3992578 YP_543479.1 CDS gldA NC_007946.1 4422249 4423391 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4422249..4423391) Escherichia coli UTI89 3992579 YP_543480.1 CDS talC NC_007946.1 4423363 4424025 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4423363..4424025) Escherichia coli UTI89 3992580 YP_543481.1 CDS ptsA NC_007946.1 4424037 4426538 R phosphoenolpyruvate-protein phosphotransferase ptsA complement(4424037..4426538) Escherichia coli UTI89 3993292 YP_543482.1 CDS frwC NC_007946.1 4426847 4427926 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4426847..4427926 Escherichia coli UTI89 3993293 YP_543483.1 CDS frwB NC_007946.1 4427941 4428261 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4427941..4428261 Escherichia coli UTI89 3993294 YP_543484.1 CDS UTI89_C4541 NC_007946.1 4427974 4428300 R hypothetical protein complement(4427974..4428300) Escherichia coli UTI89 3993295 YP_543485.1 CDS pflD NC_007946.1 4428312 4430609 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4428312..4430609 Escherichia coli UTI89 3993296 YP_543486.1 CDS pflC NC_007946.1 4430575 4431453 D pyruvate formate lyase II activase 4430575..4431453 Escherichia coli UTI89 3993297 YP_543487.1 CDS frwD NC_007946.1 4431455 4431796 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4431455..4431796 Escherichia coli UTI89 3993298 YP_543488.1 CDS yijO NC_007946.1 4431783 4432634 R transcriptional regulator YijO complement(4431783..4432634) Escherichia coli UTI89 3993299 YP_543489.1 CDS yijP NC_007946.1 4432860 4434638 R hypothetical protein complement(4432860..4434638) Escherichia coli UTI89 3993300 YP_543490.1 CDS ppc NC_007946.1 4434776 4437427 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4434776..4437427) Escherichia coli UTI89 3993301 YP_543491.1 CDS argE NC_007946.1 4437729 4438919 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4437729..4438919) Escherichia coli UTI89 3993302 YP_543492.1 CDS argC NC_007946.1 4439034 4440038 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4439034..4440038 Escherichia coli UTI89 3993303 YP_543493.1 CDS argB NC_007946.1 4440013 4440822 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4440013..4440822 Escherichia coli UTI89 3993304 YP_543494.1 CDS argH NC_007946.1 4440883 4442256 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4440883..4442256 Escherichia coli UTI89 3993305 YP_543495.1 CDS UTI89_C4552 NC_007946.1 4442754 4443968 D starvation sensing protein RspA 4442754..4443968 Escherichia coli UTI89 3993306 YP_543496.1 CDS yjiZ NC_007946.1 4444035 4445318 D transport protein YjjL 4444035..4445318 Escherichia coli UTI89 3993307 YP_543497.2 CDS oxyR NC_007946.1 4445570 4446487 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4445570..4446487 Escherichia coli UTI89 3993308 YP_543498.1 CDS sthA NC_007946.1 4446470 4447870 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4446470..4447870) Escherichia coli UTI89 3993309 YP_543499.1 CDS UTI89_C4556 NC_007946.1 4448200 4449366 D hippuricase 4448200..4449366 Escherichia coli UTI89 3993310 YP_543500.1 CDS UTI89_C4557 NC_007946.1 4449409 4450725 D citrate permease 4449409..4450725 Escherichia coli UTI89 3993311 YP_543501.1 CDS yijC NC_007946.1 4450775 4451479 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4450775..4451479 Escherichia coli UTI89 3994348 YP_543502.1 CDS yijD NC_007946.1 4451479 4451838 D hypothetical protein 4451479..4451838 Escherichia coli UTI89 3994349 YP_543503.1 CDS trmA NC_007946.1 4451878 4452978 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4451878..4452978) Escherichia coli UTI89 3994350 YP_543504.1 CDS btuB NC_007946.1 4453302 4455191 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4453302..4455191 Escherichia coli UTI89 3994351 YP_543505.1 CDS murI NC_007946.1 4455136 4455993 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4455136..4455993 Escherichia coli UTI89 3994352 YP_543509.1 CDS yjaA NC_007946.1 4461423 4461842 D hypothetical protein 4461423..4461842 Escherichia coli UTI89 3994360 YP_543510.1 CDS yjaB NC_007946.1 4461906 4462349 R hypothetical protein complement(4461906..4462349) Escherichia coli UTI89 3994361 YP_543511.1 CDS metA NC_007946.1 4462506 4463435 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4462506..4463435 Escherichia coli UTI89 3994362 YP_543512.1 CDS aceB NC_007946.1 4463686 4465305 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4463686..4465305 Escherichia coli UTI89 3991698 YP_543513.1 CDS aceA NC_007946.1 4465320 4466639 D isocitrate lyase 4465320..4466639 Escherichia coli UTI89 3991699 YP_543514.1 CDS aceK NC_007946.1 4466688 4468412 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4466688..4468412 Escherichia coli UTI89 3991700 YP_543515.2 CDS iclR NC_007946.1 4468429 4469253 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR complement(4468429..4469253) Escherichia coli UTI89 3991701 YP_543516.1 CDS metH NC_007946.1 4469453 4473136 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4469453..4473136 Escherichia coli UTI89 3991702 YP_543517.1 CDS UTI89_C4578 NC_007946.1 4473190 4473516 D hypothetical protein 4473190..4473516 Escherichia coli UTI89 3991703 YP_543518.1 CDS UTI89_C4579 NC_007946.1 4473559 4474008 D hypothetical protein 4473559..4474008 Escherichia coli UTI89 3991704 YP_543519.1 CDS yjbB NC_007946.1 4474179 4475810 D hypothetical protein 4474179..4475810 Escherichia coli UTI89 3991705 YP_543520.1 CDS pepE NC_007946.1 4475900 4476589 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4475900..4476589) Escherichia coli UTI89 3991706 YP_543521.1 CDS UTI89_C4582 NC_007946.1 4476696 4476851 D hypothetical protein 4476696..4476851 Escherichia coli UTI89 3991707 YP_543522.1 CDS UTI89_C4583 NC_007946.1 4476971 4478200 R oxidoreductase complement(4476971..4478200) Escherichia coli UTI89 3991708 YP_543523.1 CDS UTI89_C4584 NC_007946.1 4478252 4479106 R PTS system mannose-specific transporter subunit IID complement(4478252..4479106) Escherichia coli UTI89 3991709 YP_543524.1 CDS UTI89_C4585 NC_007946.1 4479087 4479884 R PTS system mannose-specific transporter subunit IIC complement(4479087..4479884) Escherichia coli UTI89 3991710 YP_543525.1 CDS UTI89_C4586 NC_007946.1 4479950 4480444 R sorbose PTS component complement(4479950..4480444) Escherichia coli UTI89 3991711 YP_543526.1 CDS UTI89_C4587 NC_007946.1 4480444 4480851 R sorbose PTS component complement(4480444..4480851) Escherichia coli UTI89 3991712 YP_543527.1 CDS UTI89_C4588 NC_007946.1 4480861 4481667 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4480861..4481667) Escherichia coli UTI89 3991713 YP_543528.1 CDS UTI89_C4589 NC_007946.1 4481737 4482768 R sorbose uptake and utilization transcriptional regulator complement(4481737..4482768) Escherichia coli UTI89 3991714 YP_543529.1 CDS yjbC NC_007946.1 4483032 4483904 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4483032..4483904 Escherichia coli UTI89 3991715 YP_543530.1 CDS yjbD NC_007946.1 4483905 4484177 R hypothetical protein complement(4483905..4484177) Escherichia coli UTI89 3991716 YP_543531.1 CDS lysC NC_007946.1 4484430 4485779 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase complement(4484430..4485779) Escherichia coli UTI89 3991717 YP_543532.1 CDS pgi NC_007946.1 4486298 4487953 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4486298..4487953 Escherichia coli UTI89 3991070 YP_543534.1 CDS UTI89_C4595 NC_007946.1 4488778 4489446 D hypothetical protein 4488778..4489446 Escherichia coli UTI89 3991072 YP_543535.1 CDS yjbG NC_007946.1 4489443 4490180 D hypothetical protein 4489443..4490180 Escherichia coli UTI89 3991073 YP_543536.1 CDS yjbH NC_007946.1 4490180 4492276 D hypothetical protein 4490180..4492276 Escherichia coli UTI89 3991074 YP_543537.1 CDS UTI89_C4598 NC_007946.1 4492280 4492441 D hypothetical protein 4492280..4492441 Escherichia coli UTI89 3991075 YP_543538.1 CDS UTI89_C4599 NC_007946.1 4492323 4492601 R hypothetical protein complement(4492323..4492601) Escherichia coli UTI89 3991076 YP_543539.1 CDS UTI89_C4600 NC_007946.1 4492598 4492720 R hypothetical protein complement(4492598..4492720) Escherichia coli UTI89 3991077 YP_543540.1 CDS yjbA NC_007946.1 4492816 4493226 D phosphate-starvation-inducible protein PsiE 4492816..4493226 Escherichia coli UTI89 3991078 YP_543541.1 CDS malG NC_007946.1 4493320 4494210 R with MalKFE is involved in the transport of maltose into the cell; maltose ABC transporter permease complement(4493320..4494210) Escherichia coli UTI89 3991079 YP_543542.1 CDS malF NC_007946.1 4494225 4495784 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4494225..4495784) Escherichia coli UTI89 3991080 YP_543543.1 CDS malE NC_007946.1 4495923 4497113 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter substrate-binding protein complement(4495923..4497113) Escherichia coli UTI89 3991081 YP_543544.1 CDS malK NC_007946.1 4497388 4498593 D with malEFG is involved in import of maltose/maltodextrin; maltose ABC transporter ATP-binding protein 4497388..4498593 Escherichia coli UTI89 3991082 YP_543545.1 CDS lamB NC_007946.1 4498665 4500005 D porin involved in the transport of maltose and maltodextrins; maltoporin 4498665..4500005 Escherichia coli UTI89 3991083 YP_543546.1 CDS malM NC_007946.1 4500319 4501248 D maltose regulon periplasmic protein 4500319..4501248 Escherichia coli UTI89 3991084 YP_543547.1 CDS UTI89_C4608 NC_007946.1 4501261 4501413 D hypothetical protein 4501261..4501413 Escherichia coli UTI89 3991085 YP_543548.1 CDS ubiC NC_007946.1 4501427 4501924 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4501427..4501924 Escherichia coli UTI89 3991086 YP_543549.1 CDS ubiA NC_007946.1 4501937 4502809 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4501937..4502809 Escherichia coli UTI89 3991087 YP_543550.2 CDS plsB NC_007946.1 4502962 4505385 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4502962..4505385) Escherichia coli UTI89 3991088 YP_543551.1 CDS dgkA NC_007946.1 4505556 4505924 D diacylglycerol kinase 4505556..4505924 Escherichia coli UTI89 3991089 YP_543552.1 CDS lexA NC_007946.1 4506034 4506642 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4506034..4506642 Escherichia coli UTI89 3991090 YP_543553.1 CDS dinF NC_007946.1 4506661 4508040 D DNA-damage-inducible SOS response protein 4506661..4508040 Escherichia coli UTI89 3991091 YP_543554.1 CDS yjbJ NC_007946.1 4508150 4508365 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4508150..4508365 Escherichia coli UTI89 3991092 YP_543555.2 CDS yjbK NC_007946.1 4508407 4508922 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4508407..4508922) Escherichia coli UTI89 3991093 YP_543556.1 CDS yjbN NC_007946.1 4509078 4510073 D tRNA-dihydrouridine synthase A 4509078..4510073 Escherichia coli UTI89 3991094 YP_543557.1 CDS pspG NC_007946.1 4509997 4510449 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4509997..4510449 Escherichia coli UTI89 3991095 YP_543558.1 CDS qor NC_007946.1 4510614 4511597 R quinone oxidoreductase, NADPH-dependent complement(4510614..4511597) Escherichia coli UTI89 3991096 YP_543559.1 CDS UTI89_C4620 NC_007946.1 4511703 4513868 R oxidoreductase complement(4511703..4513868) Escherichia coli UTI89 3991097 YP_543560.1 CDS UTI89_C4621 NC_007946.1 4513741 4515141 R transmembrane transport protein complement(4513741..4515141) Escherichia coli UTI89 3991098 YP_543561.1 CDS UTI89_C4622 NC_007946.1 4515232 4516011 R crotonase complement(4515232..4516011) Escherichia coli UTI89 3991099 YP_543562.1 CDS UTI89_C4623 NC_007946.1 4516004 4517575 R propionate CoA-transferase complement(4516004..4517575) Escherichia coli UTI89 3991100 YP_543563.1 CDS UTI89_C4624 NC_007946.1 4517804 4518865 D regulator 4517804..4518865 Escherichia coli UTI89 3991101 YP_543564.1 CDS dnaB NC_007946.1 4518902 4520353 D unwinds double stranded DNA; replicative DNA helicase 4518902..4520353 Escherichia coli UTI89 3991102 YP_543565.1 CDS alr NC_007946.1 4520406 4521485 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4520406..4521485 Escherichia coli UTI89 3991103 YP_543566.1 CDS UTI89_C4627 NC_007946.1 4521508 4522065 D transporter 4521508..4522065 Escherichia coli UTI89 3991104 YP_543567.1 CDS UTI89_C4628 NC_007946.1 4522038 4523060 D NadR transcriptional repressor / NMN adenylyltransferase 4522038..4523060 Escherichia coli UTI89 3991105 YP_543568.2 CDS tyrB NC_007946.1 4523142 4524335 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4523142..4524335 Escherichia coli UTI89 3991106 YP_543569.1 CDS sucA NC_007946.1 4524442 4527261 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4524442..4527261 Escherichia coli UTI89 3991107 YP_543570.1 CDS UTI89_C4631 NC_007946.1 4527134 4527334 R hypothetical protein complement(4527134..4527334) Escherichia coli UTI89 3991108 YP_543571.1 CDS UTI89_C4632 NC_007946.1 4527393 4528448 D dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 4527393..4528448 Escherichia coli UTI89 3991109 YP_543572.1 CDS UTI89_C4633 NC_007946.1 4528460 4529878 D subunit of 2-oxoglutarate dehydrogenase 4528460..4529878 Escherichia coli UTI89 3991110 YP_543573.1 CDS UTI89_C4634 NC_007946.1 4529900 4531069 D SucC, succinyl-CoA synthetase subunit beta 4529900..4531069 Escherichia coli UTI89 3991111 YP_543574.1 CDS UTI89_C4635 NC_007946.1 4531082 4531954 D SucD, succinyl-CoA synthetase subunit alpha 4531082..4531954 Escherichia coli UTI89 3991112 YP_543575.1 CDS UTI89_C4636 NC_007946.1 4532160 4533665 D membrane-bound protein 4532160..4533665 Escherichia coli UTI89 3991113 YP_543576.1 CDS UTI89_C4637 NC_007946.1 4533539 4534750 D lactate dehydrogenase 4533539..4534750 Escherichia coli UTI89 3991114 YP_543577.1 CDS UTI89_C4638 NC_007946.1 4534739 4536097 R c4-dicarboxylate transport transcriptional regulatory protein complement(4534739..4536097) Escherichia coli UTI89 3991115 YP_543578.1 CDS UTI89_C4639 NC_007946.1 4536090 4537910 R transport sensor protein complement(4536090..4537910) Escherichia coli UTI89 3991116 YP_543579.1 CDS UTI89_C4640 NC_007946.1 4538026 4538178 D hypothetical protein 4538026..4538178 Escherichia coli UTI89 3991117 YP_543580.1 CDS aphA NC_007946.1 4538187 4538900 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4538187..4538900 Escherichia coli UTI89 3991118 YP_543581.1 CDS yjbQ NC_007946.1 4539011 4539427 D hypothetical protein 4539011..4539427 Escherichia coli UTI89 3991119 YP_543582.1 CDS yjbR NC_007946.1 4539431 4539787 D hypothetical protein 4539431..4539787 Escherichia coli UTI89 3991120 YP_543583.1 CDS uvrA NC_007946.1 4539822 4542644 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4539822..4542644) Escherichia coli UTI89 3991121 YP_543584.2 CDS ssb NC_007946.1 4542898 4543434 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4542898..4543434 Escherichia coli UTI89 3991122 YP_543585.1 CDS yjcB NC_007946.1 4543533 4543913 R hypothetical protein complement(4543533..4543913) Escherichia coli UTI89 3991123 YP_543586.1 CDS yjcC NC_007946.1 4544234 4545829 D hypothetical protein 4544234..4545829 Escherichia coli UTI89 3991124 YP_543587.1 CDS soxS NC_007946.1 4545832 4546155 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4545832..4546155) Escherichia coli UTI89 3991125 YP_543588.1 CDS soxR NC_007946.1 4546241 4546705 D redox-sensitive transcriptional activator SoxR 4546241..4546705 Escherichia coli UTI89 3991126 YP_543589.1 CDS UTI89_C4650 NC_007946.1 4546692 4546958 D hypothetical protein 4546692..4546958 Escherichia coli UTI89 3991127 YP_543590.1 CDS yjcD NC_007946.1 4547252 4548601 D hypothetical protein 4547252..4548601 Escherichia coli UTI89 3989703 YP_543591.1 CDS yjcE NC_007946.1 4548752 4550401 D CPA1 transporter YjcE 4548752..4550401 Escherichia coli UTI89 3989704 YP_543592.1 CDS UTI89_C4653 NC_007946.1 4550437 4551321 R transcriptional regulator complement(4550437..4551321) Escherichia coli UTI89 3989705 YP_543593.1 CDS UTI89_C4654 NC_007946.1 4551333 4551461 D hypothetical protein 4551333..4551461 Escherichia coli UTI89 3989706 YP_543594.1 CDS UTI89_C4655 NC_007946.1 4551425 4551835 D hypothetical protein 4551425..4551835 Escherichia coli UTI89 3989707 YP_543595.1 CDS UTI89_C4656 NC_007946.1 4551828 4552517 D hypothetical protein 4551828..4552517 Escherichia coli UTI89 3989708 YP_543596.1 CDS actP NC_007946.1 4552556 4554205 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4552556..4554205) Escherichia coli UTI89 3989709 YP_543597.1 CDS yjcH NC_007946.1 4554202 4554516 R hypothetical protein complement(4554202..4554516) Escherichia coli UTI89 3989710 YP_543598.1 CDS acs NC_007946.1 4554808 4556766 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4554808..4556766) Escherichia coli UTI89 3989711 YP_543599.1 CDS nrfA NC_007946.1 4557158 4558594 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4557158..4558594 Escherichia coli UTI89 3989712 YP_543600.1 CDS nrfB NC_007946.1 4558633 4559205 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4558633..4559205 Escherichia coli UTI89 3989713 YP_543601.1 CDS nrfC NC_007946.1 4559202 4559873 D NrfC protein 4559202..4559873 Escherichia coli UTI89 3989714 YP_543602.1 CDS nrfD NC_007946.1 4559870 4560826 D NrfD protein 4559870..4560826 Escherichia coli UTI89 3989715 YP_543603.1 CDS nrfE NC_007946.1 4560882 4562564 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4560882..4562564 Escherichia coli UTI89 3989716 YP_543604.1 CDS nrfF NC_007946.1 4562557 4562940 D formate-dependent nitrite reductase complex subunit NrfF 4562557..4562940 Escherichia coli UTI89 3989717 YP_543605.1 CDS nrfG NC_007946.1 4562937 4563533 D formate-dependent nitrite reductase complex subunit NrfG 4562937..4563533 Escherichia coli UTI89 3989718 YP_543606.1 CDS UTI89_C4667 NC_007946.1 4563668 4563799 R hypothetical protein complement(4563668..4563799) Escherichia coli UTI89 3989719 YP_543607.1 CDS gltP NC_007946.1 4563876 4565189 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4563876..4565189 Escherichia coli UTI89 3989720 YP_543608.1 CDS yjcO NC_007946.1 4565337 4566080 R hypothetical protein complement(4565337..4566080) Escherichia coli UTI89 3989721 YP_543609.1 CDS yddO NC_007946.1 4566137 4566841 R ABC transporter ATP-binding protein complement(4566137..4566841) Escherichia coli UTI89 3989722 YP_543610.1 CDS UTI89_C4671 NC_007946.1 4566828 4567724 R oligopeptide ABC transporter complement(4566828..4567724) Escherichia coli UTI89 3990593 YP_543611.1 CDS yddQ NC_007946.1 4567657 4568490 R ABC transporter permease complement(4567657..4568490) Escherichia coli UTI89 3990594 YP_543612.1 CDS yddR NC_007946.1 4568490 4569632 R ABC transporter permease complement(4568490..4569632) Escherichia coli UTI89 3990595 YP_543613.1 CDS UTI89_C4674 NC_007946.1 4569639 4571207 R hypothetical protein complement(4569639..4571207) Escherichia coli UTI89 3990596 YP_543614.1 CDS yjcP NC_007946.1 4573927 4575393 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(4573927..4575393) Escherichia coli UTI89 3990597 YP_543615.1 CDS UTI89_C4676 NC_007946.1 4575390 4577441 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4575390..4577441) Escherichia coli UTI89 3990598 YP_543616.1 CDS yjcR NC_007946.1 4577441 4578472 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4577441..4578472) Escherichia coli UTI89 3990599 YP_543617.1 CDS UTI89_C4678 NC_007946.1 4578491 4578814 R hypothetical protein complement(4578491..4578814) Escherichia coli UTI89 3990600 YP_543618.1 CDS yjcS NC_007946.1 4578974 4580971 R hypothetical protein complement(4578974..4580971) Escherichia coli UTI89 3990601 YP_543619.1 CDS yjcT NC_007946.1 4581234 4582163 R D-allose kinase complement(4581234..4582163) Escherichia coli UTI89 3990602 YP_543620.1 CDS yjcU NC_007946.1 4582147 4582848 R allulose-6-phosphate 3-epimerase complement(4582147..4582848) Escherichia coli UTI89 3990603 YP_543621.1 CDS alsA NC_007946.1 4583812 4585344 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4583812..4585344) Escherichia coli UTI89 3990604 YP_543622.1 CDS yjcX NC_007946.1 4585471 4586412 R D-allose transporter subunit complement(4585471..4586412) Escherichia coli UTI89 3990605 YP_543623.2 CDS rpiR NC_007946.1 4586465 4587355 R involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR complement(4586465..4587355) Escherichia coli UTI89 3990606 YP_543624.1 CDS rpiB NC_007946.1 4587715 4588164 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4587715..4588164 Escherichia coli UTI89 3990607 YP_543625.1 CDS UTI89_C4686 NC_007946.1 4588233 4588562 D hypothetical protein 4588233..4588562 Escherichia coli UTI89 3990608 YP_543626.1 CDS phnP NC_007946.1 4588590 4589348 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4588590..4589348) Escherichia coli UTI89 3990609 YP_543627.1 CDS phnO NC_007946.1 4589350 4589784 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4589350..4589784) Escherichia coli UTI89 3990610 YP_543628.1 CDS phnN NC_007946.1 4589771 4590328 R ribose 1,5-bisphosphokinase complement(4589771..4590328) Escherichia coli UTI89 3990611 YP_543629.1 CDS phnM NC_007946.1 4590328 4591464 R PhnM protein complement(4590328..4591464) Escherichia coli UTI89 3990957 YP_543630.1 CDS phnL NC_007946.1 4591461 4592141 R phosphonates transport ATP-binding protein PhnL complement(4591461..4592141) Escherichia coli UTI89 3990958 YP_543631.2 CDS phnK NC_007946.1 4592252 4593010 R phosphonate C-P lyase system protein PhnK complement(4592252..4593010) Escherichia coli UTI89 3990959 YP_543632.1 CDS phnJ NC_007946.1 4593007 4593936 R PhnJ protein complement(4593007..4593936) Escherichia coli UTI89 3990960 YP_543633.1 CDS phnI NC_007946.1 4593845 4594915 R PhnI protein complement(4593845..4594915) Escherichia coli UTI89 3990961 YP_543634.1 CDS phnH NC_007946.1 4594909 4595493 R carbon-phosphorus lyase complex subunit complement(4594909..4595493) Escherichia coli UTI89 3990962 YP_543635.1 CDS phnG NC_007946.1 4595490 4595942 R PhnG protein complement(4595490..4595942) Escherichia coli UTI89 3990963 YP_543636.1 CDS phnF NC_007946.1 4595943 4596677 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4595943..4596677) Escherichia coli UTI89 3990964 YP_543637.1 CDS phnE NC_007946.1 4596689 4597531 R PhnE subunit of alkylphosphonate ABC transporter complement(4596689..4597531) Escherichia coli UTI89 3990965 YP_543638.1 CDS phnD NC_007946.1 4597574 4598590 R PhnD subunit of alkylphosphonate ABC transporter complement(4597574..4598590) Escherichia coli UTI89 3990966 YP_543639.1 CDS phnC NC_007946.1 4598615 4599403 R phosphonate/organophosphate ester transporter subunit complement(4598615..4599403) Escherichia coli UTI89 3990967 YP_543640.1 CDS phnB NC_007946.1 4599536 4599979 R hypothetical protein complement(4599536..4599979) Escherichia coli UTI89 3990968 YP_543641.1 CDS phnA NC_007946.1 4600139 4600621 R hypothetical protein complement(4600139..4600621) Escherichia coli UTI89 3990969 YP_543642.1 CDS yjdA NC_007946.1 4600877 4603105 D hypothetical protein 4600877..4603105 Escherichia coli UTI89 3990970 YP_543643.1 CDS yjcZ NC_007946.1 4603102 4603980 D hypothetical protein 4603102..4603980 Escherichia coli UTI89 3990971 YP_543644.1 CDS proP NC_007946.1 4604211 4605746 D proline/glycine betaine transporter 4604211..4605746 Escherichia coli UTI89 3990972 YP_543645.1 CDS basS NC_007946.1 4605923 4607023 R sensor protein BasS/PmrB complement(4605923..4607023) Escherichia coli UTI89 3990973 YP_543646.1 CDS basR NC_007946.1 4607024 4607692 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4607024..4607692) Escherichia coli UTI89 3990974 YP_543647.1 CDS yjdB NC_007946.1 4607689 4609377 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4607689..4609377) Escherichia coli UTI89 3990975 YP_543648.1 CDS yjdE NC_007946.1 4609436 4610773 R arginine:agmatin antiporter complement(4609436..4610773) Escherichia coli UTI89 3990976 YP_543649.1 CDS adiY NC_007946.1 4610910 4611671 R AdiY transcriptional regulatory protein complement(4610910..4611671) Escherichia coli UTI89 3990919 YP_543650.1 CDS adiA NC_007946.1 4612007 4614277 R biodegradative arginine decarboxylase complement(4612007..4614277) Escherichia coli UTI89 3990920 YP_543651.1 CDS melR NC_007946.1 4614473 4615381 R DNA-binding transcriptional regulator MelR complement(4614473..4615381) Escherichia coli UTI89 3990921 YP_543652.1 CDS melA NC_007946.1 4615664 4617019 D alpha-galactosidase 4615664..4617019 Escherichia coli UTI89 3990922 YP_543653.1 CDS yjdF NC_007946.1 4617016 4617666 R hypothetical protein complement(4617016..4617666) Escherichia coli UTI89 3990923 YP_543654.1 CDS fumB NC_007946.1 4617789 4619435 R fumarate hydratase class I, anaerobic complement(4617789..4619435) Escherichia coli UTI89 3990924 YP_543655.1 CDS dcuB NC_007946.1 4619513 4620853 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4619513..4620853) Escherichia coli UTI89 3990925 YP_543656.1 CDS UTI89_C4717 NC_007946.1 4620921 4621079 D hypothetical protein 4620921..4621079 Escherichia coli UTI89 3990926 YP_543657.1 CDS yjdG NC_007946.1 4621424 4622143 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4621424..4622143) Escherichia coli UTI89 3990927 YP_543658.1 CDS yjdH NC_007946.1 4622140 4623771 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4622140..4623771) Escherichia coli UTI89 3990928 YP_543659.1 CDS yjdI NC_007946.1 4623952 4624182 D hypothetical protein 4623952..4624182 Escherichia coli UTI89 3990929 YP_543660.1 CDS yjdJ NC_007946.1 4624194 4624466 D hypothetical protein 4624194..4624466 Escherichia coli UTI89 3990930 YP_543661.1 CDS UTI89_C4722 NC_007946.1 4624223 4624675 R hypothetical protein complement(4624223..4624675) Escherichia coli UTI89 3990931 YP_543662.1 CDS yjdK NC_007946.1 4624695 4624991 D hypothetical protein 4624695..4624991 Escherichia coli UTI89 3990932 YP_543663.1 CDS UTI89_C4724 NC_007946.1 4625019 4625192 D hypothetical protein 4625019..4625192 Escherichia coli UTI89 3990933 YP_543664.1 CDS UTI89_C4725 NC_007946.1 4625202 4625345 D hypothetical protein 4625202..4625345 Escherichia coli UTI89 3990934 YP_543665.2 CDS lysU NC_007946.1 4625311 4626828 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4625311..4626828) Escherichia coli UTI89 3990935 YP_543666.1 CDS yjdL NC_007946.1 4627065 4628522 R transporter YjdL complement(4627065..4628522) Escherichia coli UTI89 3990936 YP_543667.1 CDS cadA NC_007946.1 4628581 4630734 R CadA subunit of lysine decarboxylase complement(4628581..4630734) Escherichia coli UTI89 3990937 YP_543668.1 CDS cadB NC_007946.1 4630808 4632142 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4630808..4632142) Escherichia coli UTI89 3991032 YP_543669.1 CDS cadC NC_007946.1 4632508 4634046 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4632508..4634046) Escherichia coli UTI89 3991033 YP_543670.1 CDS yjdC NC_007946.1 4634845 4635444 R transcriptional regulator complement(4634845..4635444) Escherichia coli UTI89 3991035 YP_543671.1 CDS dipZ NC_007946.1 4635457 4637154 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4635457..4637154) Escherichia coli UTI89 3991036 YP_543672.2 CDS cutA NC_007946.1 4637130 4637468 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4637130..4637468) Escherichia coli UTI89 3991037 YP_543673.1 CDS dcuA NC_007946.1 4637584 4638885 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4637584..4638885) Escherichia coli UTI89 3991038 YP_543674.1 CDS aspA NC_007946.1 4639003 4640484 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4639003..4640484) Escherichia coli UTI89 3991039 YP_543675.1 CDS UTI89_C4737 NC_007946.1 4640475 4640591 R hypothetical protein complement(4640475..4640591) Escherichia coli UTI89 3991040 YP_543676.1 CDS fxsA NC_007946.1 4640776 4641252 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4640776..4641252 Escherichia coli UTI89 3991041 YP_543677.2 CDS yjeH NC_007946.1 4641268 4642524 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(4641268..4642524) Escherichia coli UTI89 3991042 YP_543678.1 CDS groES NC_007946.1 4642800 4643093 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4642800..4643093 Escherichia coli UTI89 3991043 YP_543679.1 CDS groEL NC_007946.1 4643137 4644783 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4643137..4644783 Escherichia coli UTI89 3991044 YP_543680.1 CDS yjeI NC_007946.1 4644888 4645274 D hypothetical protein 4644888..4645274 Escherichia coli UTI89 3991045 YP_543681.1 CDS yjeJ NC_007946.1 4645324 4646193 R hypothetical protein complement(4645324..4646193) Escherichia coli UTI89 3991046 YP_543682.1 CDS yjeK NC_007946.1 4646428 4647456 R hypothetical protein complement(4646428..4647456) Escherichia coli UTI89 3991047 YP_543683.1 CDS efp NC_007946.1 4647498 4648064 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4647498..4648064 Escherichia coli UTI89 3991048 YP_543684.1 CDS ecnA NC_007946.1 4648116 4648241 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4648116..4648241 Escherichia coli UTI89 3991049 YP_543685.1 CDS ecnB NC_007946.1 4648352 4648498 D entericidin B 4648352..4648498 Escherichia coli UTI89 3991050 YP_543686.1 CDS sugE NC_007946.1 4648611 4648991 D SugE SMR transporter 4648611..4648991 Escherichia coli UTI89 3990996 YP_543687.1 CDS blc NC_007946.1 4648988 4649521 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4648988..4649521) Escherichia coli UTI89 3990997 YP_543688.2 CDS ampC NC_007946.1 4649610 4650743 R beta-lactamase complement(4649610..4650743) Escherichia coli UTI89 3990998 YP_543689.1 CDS frdD NC_007946.1 4650806 4651165 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4650806..4651165) Escherichia coli UTI89 3990999 YP_543690.1 CDS frdC NC_007946.1 4651176 4651571 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4651176..4651571) Escherichia coli UTI89 3991000 YP_543691.1 CDS frdB NC_007946.1 4651582 4652316 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4651582..4652316) Escherichia coli UTI89 3991001 YP_543692.1 CDS frdA NC_007946.1 4652309 4654117 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4652309..4654117) Escherichia coli UTI89 3991002 YP_543693.1 CDS yjeA NC_007946.1 4654442 4655419 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4654442..4655419 Escherichia coli UTI89 3991003 YP_543694.1 CDS yjeM NC_007946.1 4655596 4657140 D transporter YjeM 4655596..4657140 Escherichia coli UTI89 3991004 YP_543695.1 CDS yjeN NC_007946.1 4657203 4657517 D hypothetical protein 4657203..4657517 Escherichia coli UTI89 3991005 YP_543696.1 CDS yjeO NC_007946.1 4657514 4657828 D hypothetical protein 4657514..4657828 Escherichia coli UTI89 3991006 YP_543697.1 CDS yjeP NC_007946.1 4657859 4661182 R hypothetical protein complement(4657859..4661182) Escherichia coli UTI89 3991007 YP_543698.1 CDS psd NC_007946.1 4661204 4662172 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4661204..4662172) Escherichia coli UTI89 3991008 YP_543699.2 CDS yjeQ NC_007946.1 4662269 4663321 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4662269..4663321) Escherichia coli UTI89 3991009 YP_543700.1 CDS orn NC_007946.1 4663299 4663961 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4663299..4663961 Escherichia coli UTI89 3991010 YP_543701.1 CDS yjeS NC_007946.1 4664740 4665924 R electron transport protein YjeS complement(4664740..4665924) Escherichia coli UTI89 3990882 YP_543702.1 CDS yjeF NC_007946.1 4665857 4667425 D hypothetical protein 4665857..4667425 Escherichia coli UTI89 3990883 YP_543703.1 CDS yjeE NC_007946.1 4667397 4667858 D possibly involved in cell wall synthesis; ATPase 4667397..4667858 Escherichia coli UTI89 3990884 YP_543704.1 CDS amiB NC_007946.1 4667862 4669214 D N-acetylmuramoyl-L-alanine amidase 4667862..4669214 Escherichia coli UTI89 3990885 YP_543705.1 CDS mutL NC_007946.1 4669221 4671071 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4669221..4671071 Escherichia coli UTI89 3990886 YP_543706.1 CDS miaA NC_007946.1 4671064 4672014 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4671064..4672014 Escherichia coli UTI89 3990887 YP_543707.1 CDS hfq NC_007946.1 4672100 4672408 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4672100..4672408 Escherichia coli UTI89 3990888 YP_543708.1 CDS hflX NC_007946.1 4672484 4673764 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4672484..4673764 Escherichia coli UTI89 3990889 YP_543709.1 CDS hflK NC_007946.1 4673850 4675109 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4673850..4675109 Escherichia coli UTI89 3990890 YP_543710.1 CDS hflC NC_007946.1 4675112 4676116 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4675112..4676116 Escherichia coli UTI89 3990891 YP_543711.1 CDS UTI89_C4776 NC_007946.1 4676198 4676395 D hypothetical protein 4676198..4676395 Escherichia coli UTI89 3990892 YP_543712.1 CDS purA NC_007946.1 4676499 4677797 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4676499..4677797 Escherichia coli UTI89 3990893 YP_543713.1 CDS yjeB NC_007946.1 4678002 4678427 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4678002..4678427 Escherichia coli UTI89 3990894 YP_543714.2 CDS vacB NC_007946.1 4678466 4680907 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4678466..4680907 Escherichia coli UTI89 3990895 YP_543715.1 CDS yjfH NC_007946.1 4680999 4681730 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4680999..4681730 Escherichia coli UTI89 3990896 YP_543716.1 CDS yjfI NC_007946.1 4681857 4682258 D hypothetical protein 4681857..4682258 Escherichia coli UTI89 3990897 YP_543717.1 CDS yjfJ NC_007946.1 4682277 4682975 D hypothetical protein 4682277..4682975 Escherichia coli UTI89 3990898 YP_543718.1 CDS yjfK NC_007946.1 4683025 4683684 D hypothetical protein 4683025..4683684 Escherichia coli UTI89 3990899 YP_543719.1 CDS yjfL NC_007946.1 4683702 4684100 D hypothetical protein 4683702..4684100 Escherichia coli UTI89 3989823 YP_543720.1 CDS yjfM NC_007946.1 4684110 4684748 D hypothetical protein 4684110..4684748 Escherichia coli UTI89 3989824 YP_543721.1 CDS yjfC NC_007946.1 4684751 4685914 D synthetase/amidase 4684751..4685914 Escherichia coli UTI89 3989825 YP_543722.1 CDS aidB NC_007946.1 4685980 4687623 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4685980..4687623 Escherichia coli UTI89 3989826 YP_543723.1 CDS yjfN NC_007946.1 4687740 4688042 R hypothetical protein complement(4687740..4688042) Escherichia coli UTI89 3989827 YP_543724.1 CDS yjfO NC_007946.1 4688164 4688592 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(4688164..4688592) Escherichia coli UTI89 3989828 YP_543725.1 CDS yjfP NC_007946.1 4688675 4689424 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4688675..4689424 Escherichia coli UTI89 3989829 YP_543726.1 CDS yjfQ NC_007946.1 4689421 4690176 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4689421..4690176) Escherichia coli UTI89 3989830 YP_543727.1 CDS yjfR NC_007946.1 4690284 4691354 R L-ascorbate 6-phosphate lactonase complement(4690284..4691354) Escherichia coli UTI89 3989831 YP_543728.1 CDS ulaA NC_007946.1 4691703 4693100 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4691703..4693100 Escherichia coli UTI89 3989832 YP_543729.1 CDS sgaB NC_007946.1 4693110 4693421 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4693110..4693421 Escherichia coli UTI89 3989833 YP_543730.1 CDS sgaA NC_007946.1 4693431 4693895 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4693431..4693895 Escherichia coli UTI89 3989834 YP_543731.2 CDS ulaD NC_007946.1 4693909 4694559 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4693909..4694559 Escherichia coli UTI89 3989835 YP_543732.1 CDS sgaU NC_007946.1 4694569 4695423 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4694569..4695423 Escherichia coli UTI89 3989836 YP_543733.2 CDS sgaE NC_007946.1 4695423 4696109 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4695423..4696109 Escherichia coli UTI89 3989837 YP_543734.1 CDS yjfY NC_007946.1 4696238 4696513 R hypothetical protein complement(4696238..4696513) Escherichia coli UTI89 3989838 YP_543735.1 CDS rpsF NC_007946.1 4696841 4697236 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4696841..4697236 Escherichia coli UTI89 3989839 YP_543736.1 CDS priB NC_007946.1 4697243 4697557 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4697243..4697557 Escherichia coli UTI89 3989840 YP_543737.1 CDS rpsR NC_007946.1 4697562 4697789 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4697562..4697789 Escherichia coli UTI89 3989841 YP_543738.1 CDS rplI NC_007946.1 4697831 4698280 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4697831..4698280 Escherichia coli UTI89 3991971 YP_543739.1 CDS UTI89_C4804 NC_007946.1 4698682 4699173 D hypothetical protein 4698682..4699173 Escherichia coli UTI89 3991972 YP_543740.1 CDS UTI89_C4805 NC_007946.1 4699176 4700444 D hypothetical protein 4699176..4700444 Escherichia coli UTI89 3991973 YP_543741.1 CDS UTI89_C4806 NC_007946.1 4700587 4701756 R hexuronate transporter complement(4700587..4701756) Escherichia coli UTI89 3991974 YP_543742.1 CDS insBcp3 NC_007946.1 4701838 4702341 R IS1 protein InsB complement(4701838..4702341) Escherichia coli UTI89 3991975 YP_543743.1 CDS insAcp3 NC_007946.1 4702260 4702535 R IS1 protein InsA complement(4702260..4702535) Escherichia coli UTI89 3991976 YP_543744.1 CDS UTI89_C4809 NC_007946.1 4702734 4704806 R oxidoreductase complement(4702734..4704806) Escherichia coli UTI89 3991977 YP_543745.1 CDS UTI89_C4810 NC_007946.1 4704803 4706344 R acetyl-CoA:acetoacetyl-CoA transferase complement(4704803..4706344) Escherichia coli UTI89 3991978 YP_543746.1 CDS UTI89_C4811 NC_007946.1 4706354 4707130 R hypothetical protein complement(4706354..4707130) Escherichia coli UTI89 3991979 YP_543747.1 CDS UTI89_C4812 NC_007946.1 4707133 4707981 R hypothetical protein complement(4707133..4707981) Escherichia coli UTI89 3991980 YP_543748.1 CDS UTI89_C4813 NC_007946.1 4707991 4708782 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(4707991..4708782) Escherichia coli UTI89 3991981 YP_543749.1 CDS UTI89_C4814 NC_007946.1 4708922 4709641 D hypothetical protein 4708922..4709641 Escherichia coli UTI89 3991982 YP_543750.1 CDS ytfB NC_007946.1 4709625 4710299 R hypothetical protein complement(4709625..4710299) Escherichia coli UTI89 3991983 YP_543751.2 CDS fklB NC_007946.1 4710481 4711101 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4710481..4711101 Escherichia coli UTI89 3991984 YP_543752.1 CDS cycA NC_007946.1 4711410 4712822 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4711410..4712822 Escherichia coli UTI89 3991985 YP_543753.1 CDS ytfE NC_007946.1 4712867 4713529 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4712867..4713529) Escherichia coli UTI89 3991986 YP_543754.1 CDS ytfF NC_007946.1 4713637 4714611 R hypothetical protein complement(4713637..4714611) Escherichia coli UTI89 3991987 YP_543755.1 CDS ytfG NC_007946.1 4714710 4715570 R hypothetical protein complement(4714710..4715570) Escherichia coli UTI89 3991988 YP_543756.1 CDS ytfH NC_007946.1 4715548 4716039 D hypothetical protein 4715548..4716039 Escherichia coli UTI89 3991989 YP_543757.1 CDS cpdB NC_007946.1 4716168 4718111 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4716168..4718111) Escherichia coli UTI89 3991990 YP_543758.1 CDS cysQ NC_007946.1 4718301 4719041 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4718301..4719041 Escherichia coli UTI89 3991991 YP_543759.1 CDS ytfJ NC_007946.1 4719031 4719588 R hypothetical protein complement(4719031..4719588) Escherichia coli UTI89 3991992 YP_543760.1 CDS ytfK NC_007946.1 4719847 4720119 D hypothetical protein 4719847..4720119 Escherichia coli UTI89 3991993 YP_543761.1 CDS ytfL NC_007946.1 4720197 4721540 R transport protein complement(4720197..4721540) Escherichia coli UTI89 3991994 YP_543762.1 CDS msrA NC_007946.1 4721863 4722567 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4721863..4722567) Escherichia coli UTI89 3991995 YP_543763.1 CDS ytfM NC_007946.1 4722707 4724440 D hypothetical protein 4722707..4724440 Escherichia coli UTI89 3991996 YP_543764.1 CDS ytfN NC_007946.1 4724437 4728216 D hypothetical protein 4724437..4728216 Escherichia coli UTI89 3991997 YP_543765.1 CDS ytfP NC_007946.1 4728219 4728560 D hypothetical protein 4728219..4728560 Escherichia coli UTI89 3991998 YP_543766.1 CDS ppa NC_007946.1 4728940 4729470 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4728940..4729470) Escherichia coli UTI89 3991999 YP_543767.1 CDS ytfQ NC_007946.1 4729780 4730736 D LACI-type transcriptional regulator 4729780..4730736 Escherichia coli UTI89 3992000 YP_543768.1 CDS ytfR NC_007946.1 4730876 4732378 D ATP-binding protein of a transport system 4730876..4732378 Escherichia coli UTI89 3992001 YP_543769.1 CDS ytfT NC_007946.1 4732368 4733414 D ABC transporter permease 4732368..4733414 Escherichia coli UTI89 3992002 YP_543770.1 CDS yjfF NC_007946.1 4733401 4734396 D membrane component of a sugar ABC transporter system; ABC transporter permease 4733401..4734396 Escherichia coli UTI89 3992003 YP_543771.1 CDS fbp NC_007946.1 4734429 4735490 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4734429..4735490) Escherichia coli UTI89 3992004 YP_543772.1 CDS yjfG NC_007946.1 4735603 4736976 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4735603..4736976 Escherichia coli UTI89 3992005 YP_543773.1 CDS yjgA NC_007946.1 4737134 4737685 R hypothetical protein complement(4737134..4737685) Escherichia coli UTI89 3992006 YP_543774.1 CDS pmbA NC_007946.1 4737779 4739131 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4737779..4739131 Escherichia coli UTI89 3992007 YP_543775.1 CDS cybC NC_007946.1 4739315 4739701 D soluble cytochrome b562 4739315..4739701 Escherichia coli UTI89 3992008 YP_543776.1 CDS nrdG NC_007946.1 4739746 4740210 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4739746..4740210) Escherichia coli UTI89 3992009 YP_543777.1 CDS nrdD NC_007946.1 4740368 4742506 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4740368..4742506) Escherichia coli UTI89 3992049 YP_543778.1 CDS treC NC_007946.1 4742900 4744555 R trehalose-6-phosphate hydrolase complement(4742900..4744555) Escherichia coli UTI89 3992050 YP_543779.1 CDS treB NC_007946.1 4744605 4746026 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC complement(4744605..4746026) Escherichia coli UTI89 3992051 YP_543780.1 CDS treR NC_007946.1 4746145 4747092 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4746145..4747092) Escherichia coli UTI89 3992052 YP_543781.1 CDS UTI89_C4846 NC_007946.1 4747142 4747330 D hypothetical protein 4747142..4747330 Escherichia coli UTI89 3992053 YP_543782.1 CDS mgtA NC_007946.1 4747471 4750167 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4747471..4750167 Escherichia coli UTI89 3992054 YP_543783.1 CDS yjgF NC_007946.1 4750373 4750831 R hypothetical protein complement(4750373..4750831) Escherichia coli UTI89 3992055 YP_543784.1 CDS UTI89_C4849 NC_007946.1 4750466 4750930 D hypothetical protein 4750466..4750930 Escherichia coli UTI89 3992056 YP_543785.1 CDS pyrI NC_007946.1 4750832 4751293 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(4750832..4751293) Escherichia coli UTI89 3992057 YP_543786.1 CDS pyrB NC_007946.1 4751306 4752241 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(4751306..4752241) Escherichia coli UTI89 3992058 YP_543787.1 CDS pyrL NC_007946.1 4752245 4752379 R pyrBI operon leader peptide complement(4752245..4752379) Escherichia coli UTI89 3992059 YP_543788.1 CDS UTI89_C4853 NC_007946.1 4752469 4753023 R hypothetical protein complement(4752469..4753023) Escherichia coli UTI89 3992060 YP_543789.1 CDS UTI89_C4854 NC_007946.1 4753073 4754521 R hypothetical protein complement(4753073..4754521) Escherichia coli UTI89 3992061 YP_543790.1 CDS argF NC_007946.1 4754533 4755564 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(4754533..4755564) Escherichia coli UTI89 3992062 YP_543791.1 CDS UTI89_C4856 NC_007946.1 4755548 4756492 R reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4755548..4756492) Escherichia coli UTI89 3992063 YP_543792.1 CDS UTI89_C4857 NC_007946.1 4756503 4757723 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(4756503..4757723) Escherichia coli UTI89 3992064 YP_543793.1 CDS UTI89_C4858 NC_007946.1 4757811 4757945 R hypothetical protein complement(4757811..4757945) Escherichia coli UTI89 3992065 YP_543794.1 CDS yjgK NC_007946.1 4758401 4758853 D hypothetical protein 4758401..4758853 Escherichia coli UTI89 3992066 YP_543795.1 CDS argI NC_007946.1 4758899 4759903 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III; ornithine carbamoyltransferase subunit F complement(4758899..4759903) Escherichia coli UTI89 3992067 YP_543796.1 CDS yjgD NC_007946.1 4760065 4760481 D hypothetical protein 4760065..4760481 Escherichia coli UTI89 3992068 YP_543797.1 CDS UTI89_C4862 NC_007946.1 4760658 4761179 R hypothetical protein complement(4760658..4761179) Escherichia coli UTI89 3991147 YP_543798.1 CDS yjgN NC_007946.1 4761354 4762541 D hypothetical protein 4761354..4762541 Escherichia coli UTI89 3991148 YP_543799.1 CDS valS NC_007946.1 4762588 4765443 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4762588..4765443) Escherichia coli UTI89 3991149 YP_543800.1 CDS holC NC_007946.1 4765443 4765886 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4765443..4765886) Escherichia coli UTI89 3991150 YP_543801.1 CDS pepA NC_007946.1 4766144 4767655 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4766144..4767655) Escherichia coli UTI89 3991151 YP_543802.1 CDS UTI89_C4867 NC_007946.1 4767880 4768008 R hypothetical protein complement(4767880..4768008) Escherichia coli UTI89 3991152 YP_543803.1 CDS yjgP NC_007946.1 4767922 4769022 D hypothetical protein 4767922..4769022 Escherichia coli UTI89 3991153 YP_543804.1 CDS yjgQ NC_007946.1 4769019 4770104 D hypothetical protein 4769019..4770104 Escherichia coli UTI89 3991154 YP_543805.1 CDS yjgR NC_007946.1 4770265 4771767 R hypothetical protein complement(4770265..4771767) Escherichia coli UTI89 3991155 YP_543806.1 CDS idnR NC_007946.1 4771845 4772873 R L-idonate regulatory protein complement(4771845..4772873) Escherichia coli UTI89 3991156 YP_543807.1 CDS idnT NC_007946.1 4772910 4774229 R IdnT L-idonate Gnt transporter complement(4772910..4774229) Escherichia coli UTI89 3991157 YP_543808.1 CDS idnO NC_007946.1 4774294 4775058 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(4774294..4775058) Escherichia coli UTI89 3991158 YP_543809.1 CDS idnD NC_007946.1 4775082 4776113 R NAD-binding; L-idonate 5-dehydrogenase complement(4775082..4776113) Escherichia coli UTI89 3991159 YP_543810.1 CDS idnK NC_007946.1 4776330 4776893 D D-gluconate kinase 4776330..4776893 Escherichia coli UTI89 3991160 YP_543811.1 CDS yjgB NC_007946.1 4776897 4777958 R oxidoreductase complement(4776897..4777958) Escherichia coli UTI89 3991161 YP_543812.1 CDS intB NC_007946.1 4778383 4779645 D prophage P4 integrase 4778383..4779645 Escherichia coli UTI89 3991163 YP_543813.1 CDS UTI89_C4879 NC_007946.1 4779745 4780008 R hypothetical protein complement(4779745..4780008) Escherichia coli UTI89 3991164 YP_543814.1 CDS UTI89_C4880 NC_007946.1 4780097 4783612 D DNA helicase superfamily protein I 4780097..4783612 Escherichia coli UTI89 3992029 YP_543815.1 CDS yjgX NC_007946.1 4783721 4784908 R hypothetical protein complement(4783721..4784908) Escherichia coli UTI89 3992030 YP_543816.1 CDS hek NC_007946.1 4785401 4786156 R adhesin complement(4785401..4786156) Escherichia coli UTI89 3992031 YP_543817.1 CDS UTI89_C4883 NC_007946.1 4786359 4786727 R hypothetical protein complement(4786359..4786727) Escherichia coli UTI89 3992032 YP_543818.1 CDS UTI89_C4884 NC_007946.1 4787205 4787342 D hypothetical protein 4787205..4787342 Escherichia coli UTI89 3992033 YP_543819.1 CDS UTI89_C4885 NC_007946.1 4787503 4787802 D hypothetical protein 4787503..4787802 Escherichia coli UTI89 3992034 YP_543820.1 CDS papX NC_007946.1 4788287 4788838 R regulator PapX protein complement(4788287..4788838) Escherichia coli UTI89 3992035 YP_543821.1 CDS papG NC_007946.1 4789101 4790108 R p pilus adhesin PapG protein complement(4789101..4790108) Escherichia coli UTI89 3992036 YP_543822.1 CDS papF NC_007946.1 4790152 4790655 R minor pilin subunit PapF complement(4790152..4790655) Escherichia coli UTI89 3992037 YP_543823.1 CDS papE NC_007946.1 4790731 4791252 R minor pilin subunit PapE complement(4790731..4791252) Escherichia coli UTI89 3992038 YP_543824.1 CDS papK NC_007946.1 4791279 4791815 R minor pilin subunit PapK complement(4791279..4791815) Escherichia coli UTI89 3992039 YP_543825.1 CDS papJ NC_007946.1 4791825 4792406 R PapJ protein complement(4791825..4792406) Escherichia coli UTI89 3992040 YP_543826.1 CDS papD NC_007946.1 4792443 4793162 R periplasmid chaperone PapD protein complement(4792443..4793162) Escherichia coli UTI89 3992041 YP_543827.1 CDS papC NC_007946.1 4793248 4795758 R outer membrane usher protein PapC complement(4793248..4795758) Escherichia coli UTI89 3992042 YP_543828.1 CDS papH NC_007946.1 4795817 4796404 R minor pilin subunit PapH complement(4795817..4796404) Escherichia coli UTI89 3992043 YP_543829.1 CDS papA NC_007946.1 4796467 4797030 R major pilin subunit PapA complement(4796467..4797030) Escherichia coli UTI89 3992044 YP_543830.1 CDS papB NC_007946.1 4797238 4797552 R pap operon regulatory protein PapB complement(4797238..4797552) Escherichia coli UTI89 3992045 YP_543831.1 CDS papI NC_007946.1 4797957 4798190 D pap operon regulatory protein PapI 4797957..4798190 Escherichia coli UTI89 3992046 YP_543832.1 CDS UTI89_C4898 NC_007946.1 4798256 4798543 D hypothetical protein 4798256..4798543 Escherichia coli UTI89 3992047 YP_543833.1 CDS UTI89_C4899 NC_007946.1 4798693 4799061 D hypothetical protein 4798693..4799061 Escherichia coli UTI89 3992048 YP_543834.1 CDS UTI89_C4900 NC_007946.1 4800111 4800587 R hypothetical protein complement(4800111..4800587) Escherichia coli UTI89 3991184 YP_543835.1 CDS UTI89_C4901 NC_007946.1 4800650 4800856 R hypothetical protein complement(4800650..4800856) Escherichia coli UTI89 3991185 YP_543836.1 CDS UTI89_C4902 NC_007946.1 4801149 4801307 R hypothetical protein complement(4801149..4801307) Escherichia coli UTI89 3991186 YP_543837.1 CDS UTI89_C4903 NC_007946.1 4801308 4801676 R hypothetical protein complement(4801308..4801676) Escherichia coli UTI89 3991187 YP_543838.1 CDS UTI89_C4904 NC_007946.1 4801952 4803031 R F17-like fimbril adhesin subunit complement(4801952..4803031) Escherichia coli UTI89 3991188 YP_543839.1 CDS UTI89_C4905 NC_007946.1 4803028 4805613 R F17-like fimbrial usher complement(4803028..4805613) Escherichia coli UTI89 3991189 YP_543840.1 CDS UTI89_C4906 NC_007946.1 4805570 4806295 R F17-like fimbrial chaperone complement(4805570..4806295) Escherichia coli UTI89 3991190 YP_543841.1 CDS UTI89_C4907 NC_007946.1 4806360 4806908 R F17-like fimbrial subunit complement(4806360..4806908) Escherichia coli UTI89 3991191 YP_543842.1 CDS UTI89_C4908 NC_007946.1 4807484 4807882 R hypothetical protein complement(4807484..4807882) Escherichia coli UTI89 3991192 YP_543843.1 CDS UTI89_C4909 NC_007946.1 4807909 4809126 R FMN-dependent dehydrogenase complement(4807909..4809126) Escherichia coli UTI89 3991193 YP_543844.1 CDS UTI89_C4910 NC_007946.1 4809177 4809560 R hypothetical protein complement(4809177..4809560) Escherichia coli UTI89 3991194 YP_543845.1 CDS UTI89_C4911 NC_007946.1 4809697 4810536 D UidR transriptional regulator 4809697..4810536 Escherichia coli UTI89 3991195 YP_543846.1 CDS UTI89_C4912 NC_007946.1 4810505 4810828 D hypothetical protein 4810505..4810828 Escherichia coli UTI89 3991196 YP_543847.1 CDS UTI89_C4913 NC_007946.1 4811392 4811577 R hypothetical protein complement(4811392..4811577) Escherichia coli UTI89 3991197 YP_543848.1 CDS UTI89_C4914 NC_007946.1 4811641 4812774 D hypothetical protein 4811641..4812774 Escherichia coli UTI89 3991198 YP_543849.1 CDS UTI89_C4915 NC_007946.1 4812884 4814452 R hypothetical protein complement(4812884..4814452) Escherichia coli UTI89 3991199 YP_543850.1 CDS UTI89_C4916 NC_007946.1 4814483 4814833 R hypothetical protein complement(4814483..4814833) Escherichia coli UTI89 3991200 YP_543851.1 CDS UTI89_C4917 NC_007946.1 4814830 4815192 R hypothetical protein complement(4814830..4815192) Escherichia coli UTI89 3991201 YP_543852.1 CDS UTI89_C4918 NC_007946.1 4816164 4816463 R hypothetical protein complement(4816164..4816463) Escherichia coli UTI89 3991202 YP_543853.1 CDS UTI89_C4919 NC_007946.1 4816557 4817009 D transposase 4816557..4817009 Escherichia coli UTI89 3990768 YP_543854.1 CDS UTI89_C4920 NC_007946.1 4817050 4817316 R hypothetical protein complement(4817050..4817316) Escherichia coli UTI89 3990769 YP_543855.1 CDS cnf1 NC_007946.1 4817383 4820427 R cytotoxic necrotizing factor 1 complement(4817383..4820427) Escherichia coli UTI89 3990770 YP_543856.1 CDS UTI89_C4922 NC_007946.1 4820705 4820983 R hypothetical protein complement(4820705..4820983) Escherichia coli UTI89 3990771 YP_543857.1 CDS UTI89_C4923 NC_007946.1 4821053 4821334 D hypothetical protein 4821053..4821334 Escherichia coli UTI89 3990772 YP_543858.1 CDS hlyD NC_007946.1 4821373 4822809 R hemolysin D complement(4821373..4822809) Escherichia coli UTI89 3990773 YP_543859.1 CDS hlyB NC_007946.1 4822828 4824951 R hemolysin secretion protein HlyB complement(4822828..4824951) Escherichia coli UTI89 3990774 YP_543860.1 CDS hlyA NC_007946.1 4825022 4828096 R hemolysin A complement(4825022..4828096) Escherichia coli UTI89 3990775 YP_543861.1 CDS hlyC NC_007946.1 4828108 4828752 R hemolysin C complement(4828108..4828752) Escherichia coli UTI89 3990776 YP_543862.1 CDS UTI89_C4928 NC_007946.1 4829804 4830046 R hypothetical protein complement(4829804..4830046) Escherichia coli UTI89 3990777 YP_543863.1 CDS UTI89_C4929 NC_007946.1 4830074 4830937 R hypothetical protein complement(4830074..4830937) Escherichia coli UTI89 3990778 YP_543864.1 CDS UTI89_C4930 NC_007946.1 4830844 4831443 R hypothetical protein complement(4830844..4831443) Escherichia coli UTI89 3990779 YP_543865.1 CDS UTI89_C4931 NC_007946.1 4831580 4832302 D response regulator 4831580..4832302 Escherichia coli UTI89 3990780 YP_543866.1 CDS UTI89_C4932 NC_007946.1 4832303 4833775 D hypothetical protein 4832303..4833775 Escherichia coli UTI89 3990781 YP_543867.1 CDS UTI89_C4933 NC_007946.1 4833855 4834208 R hypothetical protein complement(4833855..4834208) Escherichia coli UTI89 3990782 YP_543868.1 CDS UTI89_C4934 NC_007946.1 4834704 4835024 R hypothetical protein complement(4834704..4835024) Escherichia coli UTI89 3990783 YP_543869.1 CDS UTI89_C4935 NC_007946.1 4835399 4835668 R hypothetical protein complement(4835399..4835668) Escherichia coli UTI89 3990784 YP_543870.1 CDS UTI89_C4936 NC_007946.1 4836000 4837667 R hypothetical protein complement(4836000..4837667) Escherichia coli UTI89 3990785 YP_543871.1 CDS UTI89_C4937 NC_007946.1 4837681 4840641 R hypothetical protein complement(4837681..4840641) Escherichia coli UTI89 3990786 YP_543872.1 CDS UTI89_C4938 NC_007946.1 4840646 4841692 R hypothetical protein complement(4840646..4841692) Escherichia coli UTI89 3990787 YP_543873.1 CDS UTI89_C4939 NC_007946.1 4841778 4842023 R hypothetical protein complement(4841778..4842023) Escherichia coli UTI89 3990827 YP_543874.1 CDS UTI89_C4940 NC_007946.1 4842073 4842429 R hypothetical protein complement(4842073..4842429) Escherichia coli UTI89 3990828 YP_543875.1 CDS UTI89_C4941 NC_007946.1 4842439 4842870 R hypothetical protein complement(4842439..4842870) Escherichia coli UTI89 3990829 YP_543876.1 CDS UTI89_C4942 NC_007946.1 4842950 4843285 R hypothetical protein complement(4842950..4843285) Escherichia coli UTI89 3990830 YP_543877.1 CDS UTI89_C4943 NC_007946.1 4843275 4843538 R hypothetical protein complement(4843275..4843538) Escherichia coli UTI89 3990831 YP_543878.1 CDS UTI89_C4944 NC_007946.1 4843587 4843910 R hypothetical protein complement(4843587..4843910) Escherichia coli UTI89 3990832 YP_543879.1 CDS UTI89_C4945 NC_007946.1 4843995 4844381 R hypothetical protein complement(4843995..4844381) Escherichia coli UTI89 3990833 YP_543880.1 CDS UTI89_C4946 NC_007946.1 4844378 4854166 R ShlA/HecA/FhaA exofamily protein complement(4844378..4854166) Escherichia coli UTI89 3990834 YP_543881.1 CDS UTI89_C4947 NC_007946.1 4854179 4855945 R hypothetical protein complement(4854179..4855945) Escherichia coli UTI89 3990835 YP_543882.1 CDS UTI89_C4948 NC_007946.1 4856309 4856542 R hypothetical protein complement(4856309..4856542) Escherichia coli UTI89 3990836 YP_543883.1 CDS UTI89_C4949 NC_007946.1 4856640 4857299 R hypothetical protein complement(4856640..4857299) Escherichia coli UTI89 3990837 YP_543884.1 CDS UTI89_C4950 NC_007946.1 4857531 4858079 R hypothetical protein complement(4857531..4858079) Escherichia coli UTI89 3990838 YP_543886.1 CDS UTI89_C4952 NC_007946.1 4858346 4858579 R hypothetical protein complement(4858346..4858579) Escherichia coli UTI89 3990840 YP_543887.1 CDS UTI89_C4953 NC_007946.1 4858648 4859340 R hypothetical protein complement(4858648..4859340) Escherichia coli UTI89 3990841 YP_543888.1 CDS UTI89_C4954 NC_007946.1 4859455 4860021 R hypothetical protein complement(4859455..4860021) Escherichia coli UTI89 3990842 YP_543889.1 CDS UTI89_C4955 NC_007946.1 4861132 4862460 R catalyzes the formation of pyruvate from serine; D-serine dehydratase complement(4861132..4862460) Escherichia coli UTI89 3990843 YP_543890.1 CDS UTI89_C4956 NC_007946.1 4862478 4863815 R member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX complement(4862478..4863815) Escherichia coli UTI89 3990844 YP_543891.1 CDS UTI89_C4957 NC_007946.1 4864027 4864977 D regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 4864027..4864977 Escherichia coli UTI89 3990845 YP_543892.1 CDS UTI89_C4958 NC_007946.1 4865649 4865978 R hypothetical protein complement(4865649..4865978) Escherichia coli UTI89 3990690 YP_543893.1 CDS UTI89_C4959 NC_007946.1 4865994 4866395 R hypothetical protein complement(4865994..4866395) Escherichia coli UTI89 3990691 YP_543894.1 CDS UTI89_C4960 NC_007946.1 4866428 4867093 R hypothetical protein complement(4866428..4867093) Escherichia coli UTI89 3990692 YP_543895.1 CDS UTI89_C4961 NC_007946.1 4867105 4867725 R hypothetical protein complement(4867105..4867725) Escherichia coli UTI89 3990693 YP_543896.1 CDS UTI89_C4962 NC_007946.1 4867722 4868186 R hypothetical protein complement(4867722..4868186) Escherichia coli UTI89 3990694 YP_543897.1 CDS UTI89_C4963 NC_007946.1 4868198 4869145 R hypothetical protein complement(4868198..4869145) Escherichia coli UTI89 3990695 YP_543898.1 CDS UTI89_C4964 NC_007946.1 4869197 4872619 R hypothetical protein complement(4869197..4872619) Escherichia coli UTI89 3990696 YP_543899.1 CDS UTI89_C4965 NC_007946.1 4872610 4873764 R hypothetical protein complement(4872610..4873764) Escherichia coli UTI89 3990697 YP_543900.1 CDS UTI89_C4966 NC_007946.1 4873780 4874037 R hypothetical protein complement(4873780..4874037) Escherichia coli UTI89 3990698 YP_543901.1 CDS UTI89_C4967 NC_007946.1 4874064 4875650 R hypothetical protein complement(4874064..4875650) Escherichia coli UTI89 3990699 YP_543902.1 CDS UTI89_C4968 NC_007946.1 4875704 4875982 R hypothetical protein complement(4875704..4875982) Escherichia coli UTI89 3990700 YP_543903.1 CDS UTI89_C4969 NC_007946.1 4875997 4876281 R hypothetical protein complement(4875997..4876281) Escherichia coli UTI89 3990701 YP_543904.1 CDS UTI89_C4970 NC_007946.1 4876299 4876577 R hypothetical protein complement(4876299..4876577) Escherichia coli UTI89 3990702 YP_543905.1 CDS UTI89_C4971 NC_007946.1 4876758 4877018 D hypothetical protein 4876758..4877018 Escherichia coli UTI89 3990703 YP_543906.1 CDS UTI89_C4972 NC_007946.1 4877097 4877615 R hypothetical protein complement(4877097..4877615) Escherichia coli UTI89 3990704 YP_543907.1 CDS UTI89_C4973 NC_007946.1 4877615 4878433 R hypothetical protein complement(4877615..4878433) Escherichia coli UTI89 3990705 YP_543908.1 CDS UTI89_C4974 NC_007946.1 4878456 4879034 R hypothetical protein complement(4878456..4879034) Escherichia coli UTI89 3990706 YP_543909.1 CDS UTI89_C4975 NC_007946.1 4879325 4880215 R hypothetical protein complement(4879325..4880215) Escherichia coli UTI89 3990707 YP_543910.1 CDS UTI89_C4976 NC_007946.1 4880212 4880538 R hypothetical protein complement(4880212..4880538) Escherichia coli UTI89 3990708 YP_543911.1 CDS UTI89_C4977 NC_007946.1 4881012 4882190 D hypothetical protein 4881012..4882190 Escherichia coli UTI89 3990709 YP_543912.1 CDS UTI89_C4978 NC_007946.1 4882183 4883634 D Na+/H+ antiporter 4882183..4883634 Escherichia coli UTI89 3994329 YP_543913.1 CDS UTI89_C4979 NC_007946.1 4884434 4884913 D hypothetical protein 4884434..4884913 Escherichia coli UTI89 3994330 YP_543914.1 CDS UTI89_C4980 NC_007946.1 4884948 4885826 R hypothetical protein complement(4884948..4885826) Escherichia coli UTI89 3994331 YP_543915.1 CDS UTI89_C4981 NC_007946.1 4886154 4886885 R hypothetical protein complement(4886154..4886885) Escherichia coli UTI89 3994332 YP_543916.1 CDS UTI89_C4982 NC_007946.1 4886296 4886442 D hypothetical protein 4886296..4886442 Escherichia coli UTI89 3994333 YP_543917.1 CDS UTI89_C4983 NC_007946.1 4888368 4889591 R hypothetical protein complement(4888368..4889591) Escherichia coli UTI89 3994334 YP_543918.1 CDS UTI89_C4984 NC_007946.1 4889692 4890576 D hypothetical protein 4889692..4890576 Escherichia coli UTI89 3994335 YP_543919.1 CDS UTI89_C4985 NC_007946.1 4890595 4890750 D hypothetical protein 4890595..4890750 Escherichia coli UTI89 3994336 YP_543920.1 CDS UTI89_C4986 NC_007946.1 4890779 4891459 D hypothetical protein 4890779..4891459 Escherichia coli UTI89 3994337 YP_543921.1 CDS UTI89_C4987 NC_007946.1 4891343 4891474 R hypothetical protein complement(4891343..4891474) Escherichia coli UTI89 3994338 YP_543922.1 CDS UTI89_C4988 NC_007946.1 4891502 4892284 D hypothetical protein 4891502..4892284 Escherichia coli UTI89 3994339 YP_543923.1 CDS ykfF NC_007946.1 4892290 4892523 D hypothetical protein 4892290..4892523 Escherichia coli UTI89 3994340 YP_543924.1 CDS UTI89_C4990 NC_007946.1 4892613 4893431 D hypothetical protein 4892613..4893431 Escherichia coli UTI89 3994341 YP_543925.1 CDS UTI89_C4991 NC_007946.1 4893522 4894007 D hypothetical protein 4893522..4894007 Escherichia coli UTI89 3994342 YP_543926.1 CDS UTI89_C4992 NC_007946.1 4893576 4893971 R hypothetical protein complement(4893576..4893971) Escherichia coli UTI89 3994343 YP_543927.1 CDS UTI89_C4993 NC_007946.1 4893956 4894444 R hypothetical protein complement(4893956..4894444) Escherichia coli UTI89 3994344 YP_543928.1 CDS yeeS2 NC_007946.1 4894022 4894498 D hypothetical protein 4894022..4894498 Escherichia coli UTI89 3994345 YP_543929.1 CDS yeeT2 NC_007946.1 4894585 4894806 D hypothetical protein 4894585..4894806 Escherichia coli UTI89 3994346 YP_543930.1 CDS yeeU2 NC_007946.1 4894886 4895254 D hypothetical protein 4894886..4895254 Escherichia coli UTI89 3994347 YP_543931.1 CDS yeeV2 NC_007946.1 4895344 4895721 D hypothetical protein 4895344..4895721 Escherichia coli UTI89 3992254 YP_543932.1 CDS UTI89_C4998 NC_007946.1 4895718 4896206 D hypothetical protein 4895718..4896206 Escherichia coli UTI89 3992255 YP_543933.1 CDS UTI89_C4999 NC_007946.1 4896218 4896415 D hypothetical protein 4896218..4896415 Escherichia coli UTI89 3992256 YP_543934.1 CDS UTI89_C5000 NC_007946.1 4896500 4896652 D hypothetical protein 4896500..4896652 Escherichia coli UTI89 3992257 YP_543935.1 CDS UTI89_C5001 NC_007946.1 4896671 4897135 D hypothetical protein 4896671..4897135 Escherichia coli UTI89 3992258 YP_543936.1 CDS UTI89_C5002 NC_007946.1 4897664 4899640 D hypothetical protein 4897664..4899640 Escherichia coli UTI89 3992259 YP_543937.1 CDS UTI89_C5003 NC_007946.1 4900039 4900218 R hypothetical protein complement(4900039..4900218) Escherichia coli UTI89 3992260 YP_543938.1 CDS UTI89_C5004 NC_007946.1 4900263 4901168 R hypothetical protein complement(4900263..4901168) Escherichia coli UTI89 3992261 YP_543939.1 CDS yjhS NC_007946.1 4901347 4902327 R hypothetical protein complement(4901347..4902327) Escherichia coli UTI89 3992262 YP_543940.1 CDS UTI89_C5006 NC_007946.1 4902392 4903606 R N-acetylneuraminic acid mutarotase complement(4902392..4903606) Escherichia coli UTI89 3992263 YP_543941.1 CDS yjhA NC_007946.1 4903518 4904243 R hypothetical protein complement(4903518..4904243) Escherichia coli UTI89 3992264 YP_543942.1 CDS UTI89_C5008 NC_007946.1 4905033 4905440 R hypothetical protein complement(4905033..4905440) Escherichia coli UTI89 3992265 YP_543943.1 CDS fimB NC_007946.1 4905700 4906302 D inversion of on/off regulator of fimA; tyrosine recombinase 4905700..4906302 Escherichia coli UTI89 3992266 YP_543944.1 CDS fimE NC_007946.1 4906780 4907376 D inversion of on/off regulator of fimA; tyrosine recombinase 4906780..4907376 Escherichia coli UTI89 3992267 YP_543945.1 CDS fimA NC_007946.1 4907857 4908411 D type 1 fimbriae major subunit FimA 4907857..4908411 Escherichia coli UTI89 3992268 YP_543946.1 CDS fimI NC_007946.1 4908368 4909015 D FimI fimbrial protein 4908368..4909015 Escherichia coli UTI89 3992269 YP_543947.1 CDS fimC NC_007946.1 4909052 4909777 D periplasmic chaperone protein FimC 4909052..4909777 Escherichia coli UTI89 3992270 YP_543948.1 CDS fimD NC_007946.1 4909843 4912479 D outer membrane usher protein FimD 4909843..4912479 Escherichia coli UTI89 3992271 YP_543949.1 CDS fimF NC_007946.1 4912489 4913019 D type 1 fimbriae minor subunit FimF 4912489..4913019 Escherichia coli UTI89 3992272 YP_543950.1 CDS fimG NC_007946.1 4913032 4913535 D type 1 fimbriae minor subunit FimG 4913032..4913535 Escherichia coli UTI89 3992273 YP_543951.1 CDS fimH NC_007946.1 4913555 4914457 D type 1 fimbiral adhesin FimH 4913555..4914457 Escherichia coli UTI89 3992235 YP_543952.1 CDS uxuA NC_007946.1 4915186 4916370 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4915186..4916370 Escherichia coli UTI89 3992236 YP_543953.1 CDS uxuB NC_007946.1 4916451 4917911 D D-mannonate oxidoreductase 4916451..4917911 Escherichia coli UTI89 3992237 YP_543954.1 CDS uxuR NC_007946.1 4918126 4918899 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4918126..4918899 Escherichia coli UTI89 3992238 YP_543955.1 CDS iraD NC_007946.1 4919313 4919696 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4919313..4919696 Escherichia coli UTI89 3992239 YP_543956.1 CDS pptE NC_007946.1 4919744 4922125 R phosphoenolpyruvate-protein phosphoryltransferase PptE complement(4919744..4922125) Escherichia coli UTI89 3992240 YP_543957.1 CDS pgdK NC_007946.1 4922129 4922761 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(4922129..4922761) Escherichia coli UTI89 3992241 YP_543958.1 CDS UTI89_C5024 NC_007946.1 4922774 4923844 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(4922774..4923844) Escherichia coli UTI89 3992242 YP_543959.1 CDS gldA NC_007946.1 4924163 4925245 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4924163..4925245 Escherichia coli UTI89 3992243 YP_543960.1 CDS cgxT NC_007946.1 4925312 4926580 D transporter CgxT 4925312..4926580 Escherichia coli UTI89 3992244 YP_543961.1 CDS cdlD NC_007946.1 4926598 4927962 D dihydrolipoamide dehydrogenase CdlD 4926598..4927962 Escherichia coli UTI89 3992245 YP_543962.1 CDS cniT NC_007946.1 4928263 4929804 D carnitine transporter CniT 4928263..4929804 Escherichia coli UTI89 3992246 YP_543963.1 CDS gclK NC_007946.1 4929860 4931002 R glycerate kinase GclK complement(4929860..4931002) Escherichia coli UTI89 3992247 YP_543964.1 CDS ghbD NC_007946.1 4931077 4931964 R 3-hydroxyisobutyrate dehydrogenase complement(4931077..4931964) Escherichia coli UTI89 3992248 YP_543965.1 CDS gclR NC_007946.1 4931982 4932764 R regulatory protein GclR complement(4931982..4932764) Escherichia coli UTI89 3992249 YP_543966.1 CDS gclA NC_007946.1 4932777 4934516 R catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase complement(4932777..4934516) Escherichia coli UTI89 3992250 YP_543967.1 CDS ibgR NC_007946.1 4934895 4936844 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 4934895..4936844 Escherichia coli UTI89 3992251 YP_543968.1 CDS UTI89_C5034 NC_007946.1 4936851 4937108 R hypothetical protein complement(4936851..4937108) Escherichia coli UTI89 3992252 YP_543969.1 CDS ibeA NC_007946.1 4937131 4938501 D invasion protein IbeA 4937131..4938501 Escherichia coli UTI89 3992253 YP_543970.1 CDS ibgT NC_007946.1 4938516 4939919 D transporter IbgT 4938516..4939919 Escherichia coli UTI89 3991738 YP_543971.1 CDS yjiE NC_007946.1 4940006 4940734 R DNA-binding transcriptional regulator complement(4940006..4940734) Escherichia coli UTI89 3991739 YP_543972.1 CDS iadA NC_007946.1 4940982 4942154 R isoaspartyl dipeptidase complement(4940982..4942154) Escherichia coli UTI89 3991740 YP_543973.1 CDS yjiG NC_007946.1 4942167 4942628 R hypothetical protein complement(4942167..4942628) Escherichia coli UTI89 3991741 YP_543974.1 CDS yjiH NC_007946.1 4942625 4943320 R hypothetical protein complement(4942625..4943320) Escherichia coli UTI89 3991742 YP_543975.1 CDS yjiJ NC_007946.1 4944124 4945302 R hypothetical protein complement(4944124..4945302) Escherichia coli UTI89 3991743 YP_543976.1 CDS yjiK NC_007946.1 4945370 4946341 R hypothetical protein complement(4945370..4946341) Escherichia coli UTI89 3991744 YP_543977.1 CDS UTI89_C5043 NC_007946.1 4946295 4946552 R hypothetical protein complement(4946295..4946552) Escherichia coli UTI89 3991745 YP_543978.1 CDS yjiL NC_007946.1 4946549 4947322 R hypothetical protein complement(4946549..4947322) Escherichia coli UTI89 3991746 YP_543979.1 CDS yjiM NC_007946.1 4947326 4948498 R hypothetical protein complement(4947326..4948498) Escherichia coli UTI89 3991747 YP_543980.1 CDS yjiN NC_007946.1 4948593 4949909 R hypothetical protein complement(4948593..4949909) Escherichia coli UTI89 3991748 YP_543981.1 CDS UTI89_C5047 NC_007946.1 4950058 4950978 D hypothetical protein 4950058..4950978 Escherichia coli UTI89 3991749 YP_543982.1 CDS UTI89_C5048 NC_007946.1 4951258 4953477 D hypothetical protein 4951258..4953477 Escherichia coli UTI89 3991750 YP_543983.1 CDS yjiW NC_007946.1 4953524 4953865 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(4953524..4953865) Escherichia coli UTI89 3991751 YP_543984.1 CDS hsdS NC_007946.1 4954094 4955461 R specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS complement(4954094..4955461) Escherichia coli UTI89 3991752 YP_543985.1 CDS hsdM NC_007946.1 4955458 4957047 R DNA methylase M complement(4955458..4957047) Escherichia coli UTI89 3991753 YP_543986.1 CDS UTI89_C5052 NC_007946.1 4957133 4957243 R hypothetical protein complement(4957133..4957243) Escherichia coli UTI89 3991754 YP_543987.1 CDS hsdR NC_007946.1 4957249 4960758 R restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R complement(4957249..4960758) Escherichia coli UTI89 3991755 YP_543988.1 CDS mrr NC_007946.1 4960949 4961863 D Mrr protein 4960949..4961863 Escherichia coli UTI89 3991756 YP_543989.1 CDS yjiA NC_007946.1 4961909 4962904 R GTP-binding protein YjiA complement(4961909..4962904) Escherichia coli UTI89 3991757 YP_543990.1 CDS UTI89_C5056 NC_007946.1 4962876 4963079 R hypothetical protein complement(4962876..4963079) Escherichia coli UTI89 3994519 YP_543991.1 CDS yjiY NC_007946.1 4963197 4965362 R hypothetical protein complement(4963197..4965362) Escherichia coli UTI89 3994520 YP_543992.1 CDS tsr NC_007946.1 4965724 4967379 D tsr subunit of methyl-accepting chemotaxis protein I 4965724..4967379 Escherichia coli UTI89 3994521 YP_543993.1 CDS UTI89_C5059 NC_007946.1 4967422 4968693 R hypothetical protein complement(4967422..4968693) Escherichia coli UTI89 3994522 YP_543994.1 CDS UTI89_C5060 NC_007946.1 4968690 4969163 R hypothetical protein complement(4968690..4969163) Escherichia coli UTI89 3994523 YP_543995.1 CDS UTI89_C5061 NC_007946.1 4969227 4970198 R C4-dicarboxylate-binding periplasmic protein complement(4969227..4970198) Escherichia coli UTI89 3994524 YP_543996.1 CDS UTI89_C5062 NC_007946.1 4970868 4972541 D Na(+)/H(+) exchanger YjcE 4970868..4972541 Escherichia coli UTI89 3994525 YP_543997.1 CDS yjjM NC_007946.1 4972712 4973617 R hypothetical protein complement(4972712..4973617) Escherichia coli UTI89 3994526 YP_543998.1 CDS UTI89_C5064 NC_007946.1 4973756 4974778 D zinc-type alcohol dehydrogenase-like protein YjjN 4973756..4974778 Escherichia coli UTI89 3994527 YP_543999.1 CDS mdoB NC_007946.1 4974918 4977209 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4974918..4977209) Escherichia coli UTI89 3994528 YP_544000.1 CDS yjjA NC_007946.1 4977463 4977960 R hypothetical protein complement(4977463..4977960) Escherichia coli UTI89 3994529 YP_544001.1 CDS dnaC NC_007946.1 4978006 4978743 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4978006..4978743) Escherichia coli UTI89 3994530 YP_544002.1 CDS dnaT NC_007946.1 4978746 4979285 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4978746..4979285) Escherichia coli UTI89 3994531 YP_544003.1 CDS yjjB NC_007946.1 4979393 4979881 R hypothetical protein complement(4979393..4979881) Escherichia coli UTI89 3994532 YP_544004.1 CDS yjjP NC_007946.1 4979857 4980690 R hypothetical protein complement(4979857..4980690) Escherichia coli UTI89 3994533 YP_544005.1 CDS yjjQ NC_007946.1 4981247 4981972 D hypothetical protein 4981247..4981972 Escherichia coli UTI89 3994534 YP_544006.2 CDS bglJ NC_007946.1 4981984 4982607 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4981984..4982607 Escherichia coli UTI89 3994535 YP_544007.1 CDS fhuF NC_007946.1 4982645 4983433 R ferric iron reductase involved in ferric hydroximate transport complement(4982645..4983433) Escherichia coli UTI89 3994536 YP_544008.1 CDS UTI89_C5074 NC_007946.1 4983463 4983810 D hypothetical protein 4983463..4983810 Escherichia coli UTI89 3994537 YP_544009.1 CDS UTI89_C5078 NC_007946.1 4984237 4984359 R hypothetical protein complement(4984237..4984359) Escherichia coli UTI89 3992072 YP_544010.1 CDS rsmC NC_007946.1 4984371 4985402 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4984371..4985402) Escherichia coli UTI89 3992073 YP_544012.1 CDS holD NC_007946.1 4985505 4985918 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4985505..4985918 Escherichia coli UTI89 3992075 YP_544013.1 CDS rimI NC_007946.1 4985887 4986333 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4985887..4986333 Escherichia coli UTI89 3992076 YP_544014.1 CDS yjjG NC_007946.1 4986348 4987025 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4986348..4987025 Escherichia coli UTI89 3992077 YP_544015.1 CDS UTI89_C5084 NC_007946.1 4987089 4987190 D peptide chain release factor 3 4987089..4987190 Escherichia coli UTI89 3992078 YP_544016.1 CDS UTI89_C5085 NC_007946.1 4987411 4988625 D integrase-like protein 4987411..4988625 Escherichia coli UTI89 3992079 YP_544017.1 CDS UTI89_C5086 NC_007946.1 4989001 4989996 R hypothetical protein complement(4989001..4989996) Escherichia coli UTI89 3992080 YP_544018.1 CDS UTI89_C5087 NC_007946.1 4990564 4991358 R hypothetical protein complement(4990564..4991358) Escherichia coli UTI89 3992081 YP_544019.1 CDS UTI89_C5088 NC_007946.1 4991355 4991720 R hypothetical protein complement(4991355..4991720) Escherichia coli UTI89 3992082 YP_544020.1 CDS UTI89_C5089 NC_007946.1 4991722 4992078 R hypothetical protein complement(4991722..4992078) Escherichia coli UTI89 3992083 YP_544021.1 CDS UTI89_C5090 NC_007946.1 4992078 4992440 R hypothetical protein complement(4992078..4992440) Escherichia coli UTI89 3992084 YP_544022.1 CDS yfdR2 NC_007946.1 4992431 4992967 R hypothetical protein complement(4992431..4992967) Escherichia coli UTI89 3994363 YP_544023.1 CDS yfdQ2 NC_007946.1 4993095 4993919 R hypothetical protein complement(4993095..4993919) Escherichia coli UTI89 3994364 YP_544024.1 CDS UTI89_C5093 NC_007946.1 4993985 4994533 R hypothetical protein complement(4993985..4994533) Escherichia coli UTI89 3994365 YP_544025.1 CDS UTI89_C5094 NC_007946.1 4994605 4994973 D hypothetical protein 4994605..4994973 Escherichia coli UTI89 3994366 YP_544026.1 CDS UTI89_C5095 NC_007946.1 4995070 4995762 R regulatory protein complement(4995070..4995762) Escherichia coli UTI89 3994367 YP_544027.1 CDS UTI89_C5096 NC_007946.1 4995860 4996120 D hypothetical protein 4995860..4996120 Escherichia coli UTI89 3994368 YP_544028.1 CDS UTI89_C5097 NC_007946.1 4996113 4996664 D hypothetical protein 4996113..4996664 Escherichia coli UTI89 3994369 YP_544029.1 CDS UTI89_C5098 NC_007946.1 4996661 4997812 D antirepressor 4996661..4997812 Escherichia coli UTI89 3994370 YP_544030.1 CDS UTI89_C5099 NC_007946.1 4997809 4998033 D hypothetical protein 4997809..4998033 Escherichia coli UTI89 3994371 YP_544031.1 CDS UTI89_C5100 NC_007946.1 4998030 4998848 D replication protein 4998030..4998848 Escherichia coli UTI89 3994372 YP_544032.1 CDS yfdN2 NC_007946.1 4998845 4999339 D hypothetical protein 4998845..4999339 Escherichia coli UTI89 3994373 YP_544033.1 CDS UTI89_C5102 NC_007946.1 4999339 4999992 D DNA adenine methylase 4999339..4999992 Escherichia coli UTI89 3994374 YP_544034.1 CDS UTI89_C5103 NC_007946.1 4999989 5000315 D hypothetical protein 4999989..5000315 Escherichia coli UTI89 3994375 YP_544035.1 CDS UTI89_C5104 NC_007946.1 5000312 5000701 D hypothetical protein 5000312..5000701 Escherichia coli UTI89 3994376 YP_544036.1 CDS UTI89_C5105 NC_007946.1 5000721 5001518 D hypothetical protein 5000721..5001518 Escherichia coli UTI89 3994377 YP_544037.1 CDS ydfU2 NC_007946.1 5001520 5002515 D hypothetical protein 5001520..5002515 Escherichia coli UTI89 3994378 YP_544038.1 CDS ybcQ2 NC_007946.1 5002533 5002898 D Q protein 5002533..5002898 Escherichia coli UTI89 3994379 YP_544039.1 CDS UTI89_C5108 NC_007946.1 5002983 5003429 R hypothetical protein complement(5002983..5003429) Escherichia coli UTI89 3994380 YP_544040.1 CDS UTI89_C5109 NC_007946.1 5003676 5003903 D prophage CP-933O hypothetical protein 5003676..5003903 Escherichia coli UTI89 3994381 YP_544041.1 CDS UTI89_C5110 NC_007946.1 5004054 5005106 D hypothetical protein 5004054..5005106 Escherichia coli UTI89 3994382 YP_544042.1 CDS ybcR2 NC_007946.1 5005174 5005389 D lambdoid prophage DLP12 lysis protein S-like protein 5005174..5005389 Escherichia coli UTI89 3993737 YP_544043.1 CDS ybcS2 NC_007946.1 5005389 5005886 D bacteriophage lambda lysozyme-like protein 5005389..5005886 Escherichia coli UTI89 3993738 YP_544044.1 CDS UTI89_C5113 NC_007946.1 5005883 5006350 D endopeptidase Rz of prophage CP-933K 5005883..5006350 Escherichia coli UTI89 3993739 YP_544045.1 CDS UTI89_C5114 NC_007946.1 5006338 5006490 D hypothetical protein 5006338..5006490 Escherichia coli UTI89 3993740 YP_544046.1 CDS UTI89_C5115 NC_007946.1 5006736 5007176 D hypothetical protein 5006736..5007176 Escherichia coli UTI89 3993741 YP_544047.1 CDS UTI89_C5116 NC_007946.1 5007166 5007657 D hypothetical protein 5007166..5007657 Escherichia coli UTI89 3993742 YP_544048.1 CDS UTI89_C5117 NC_007946.1 5007657 5009759 D prophage prophage DNA packaging protein 5007657..5009759 Escherichia coli UTI89 3993743 YP_544049.1 CDS UTI89_C5118 NC_007946.1 5009750 5009968 D hypothetical protein 5009750..5009968 Escherichia coli UTI89 3993744 YP_544050.1 CDS UTI89_C5119 NC_007946.1 5009896 5011476 D portal protein 5009896..5011476 Escherichia coli UTI89 3993745 YP_544051.1 CDS UTI89_C5120 NC_007946.1 5011325 5013448 D protease/scaffold protein 5011325..5013448 Escherichia coli UTI89 3993746 YP_544052.1 CDS UTI89_C5121 NC_007946.1 5013490 5013858 D hypothetical protein 5013490..5013858 Escherichia coli UTI89 3993747 YP_544053.1 CDS UTI89_C5122 NC_007946.1 5013851 5014126 D prophage CP-933K hypothetical protein 5013851..5014126 Escherichia coli UTI89 3993748 YP_544054.1 CDS UTI89_C5123 NC_007946.1 5014138 5014728 D tail component of prophage CP-933K 5014138..5014728 Escherichia coli UTI89 3993749 YP_544055.1 CDS UTI89_C5124 NC_007946.1 5014725 5015126 D tail component of prophage CP-933K 5014725..5015126 Escherichia coli UTI89 3993750 YP_544056.1 CDS UTI89_C5125 NC_007946.1 5015131 5015880 D tail component of prophage CP-933K 5015131..5015880 Escherichia coli UTI89 3993751 YP_544057.1 CDS UTI89_C5126 NC_007946.1 5015938 5016327 D tail component of prophage CP-933K 5015938..5016327 Escherichia coli UTI89 3993752 YP_544058.1 CDS UTI89_C5127 NC_007946.1 5016336 5016665 D minor tail protein 5016336..5016665 Escherichia coli UTI89 3993753 YP_544059.1 CDS UTI89_C5128 NC_007946.1 5016637 5019693 D tail length tape measure protein 5016637..5019693 Escherichia coli UTI89 3993754 YP_544060.1 CDS UTI89_C5129 NC_007946.1 5019693 5020022 D minor tail protein 5019693..5020022 Escherichia coli UTI89 3993755 YP_544061.1 CDS UTI89_C5130 NC_007946.1 5020032 5020730 D minor tail protein 5020032..5020730 Escherichia coli UTI89 3993560 YP_544062.1 CDS UTI89_C5131 NC_007946.1 5020693 5021478 D prophage tail fiber component K 5020693..5021478 Escherichia coli UTI89 3993561 YP_544063.1 CDS UTI89_C5132 NC_007946.1 5021376 5022023 D tail component of prophage CP-933K 5021376..5022023 Escherichia coli UTI89 3993562 YP_544064.1 CDS UTI89_C5133 NC_007946.1 5022084 5025479 D prophage tail component 5022084..5025479 Escherichia coli UTI89 3993563 YP_544065.1 CDS UTI89_C5134 NC_007946.1 5025547 5026146 D prophage protein 5025547..5026146 Escherichia coli UTI89 3993564 YP_544066.1 CDS UTI89_C5135 NC_007946.1 5026211 5028586 D hypothetical protein 5026211..5028586 Escherichia coli UTI89 3993565 YP_544067.1 CDS UTI89_C5136 NC_007946.1 5026576 5027016 R hypothetical protein complement(5026576..5027016) Escherichia coli UTI89 3993566 YP_544068.1 CDS UTI89_C5137 NC_007946.1 5028586 5028867 D hypothetical protein 5028586..5028867 Escherichia coli UTI89 3993567 YP_544069.1 CDS UTI89_C5138 NC_007946.1 5028877 5029917 D hypothetical protein 5028877..5029917 Escherichia coli UTI89 3993568 YP_544070.1 CDS UTI89_C5139 NC_007946.1 5030040 5030504 R hypothetical protein complement(5030040..5030504) Escherichia coli UTI89 3993569 YP_544071.1 CDS UTI89_C5140 NC_007946.1 5030557 5031315 R hypothetical protein complement(5030557..5031315) Escherichia coli UTI89 3993570 YP_544072.1 CDS UTI89_C5141 NC_007946.1 5031414 5032448 R hypothetical protein complement(5031414..5032448) Escherichia coli UTI89 3993571 YP_544073.1 CDS UTI89_C5142 NC_007946.1 5032591 5032848 D hypothetical protein 5032591..5032848 Escherichia coli UTI89 3993572 YP_544074.1 CDS UTI89_C5143 NC_007946.1 5032895 5033143 R DNA damage-inducible protein complement(5032895..5033143) Escherichia coli UTI89 3993573 YP_544075.1 CDS prfC NC_007946.1 5033363 5034949 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5033363..5034949 Escherichia coli UTI89 3993574 YP_544076.1 CDS osmY NC_007946.1 5035264 5035947 D periplasmic protein 5035264..5035947 Escherichia coli UTI89 3993575 YP_544077.1 CDS UTI89_C5146 NC_007946.1 5036044 5036235 D hypothetical protein 5036044..5036235 Escherichia coli UTI89 3993576 YP_544078.1 CDS yjjU NC_007946.1 5036321 5037430 D hypothetical protein 5036321..5037430 Escherichia coli UTI89 3993577 YP_544079.1 CDS yjjV NC_007946.1 5037427 5038206 D deoxyribonuclease YjjV 5037427..5038206 Escherichia coli UTI89 3993578 YP_544080.1 CDS yjjW NC_007946.1 5038423 5039286 R hypothetical protein complement(5038423..5039286) Escherichia coli UTI89 3993579 YP_544081.1 CDS yjjI NC_007946.1 5039258 5040808 R hypothetical protein complement(5039258..5040808) Escherichia coli UTI89 3993541 YP_544082.1 CDS UTI89_C5151 NC_007946.1 5040784 5040909 D hypothetical protein 5040784..5040909 Escherichia coli UTI89 3993542 YP_544083.1 CDS deoC NC_007946.1 5041042 5041845 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5041042..5041845 Escherichia coli UTI89 3993543 YP_544084.2 CDS deoA NC_007946.1 5041923 5043245 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5041923..5043245 Escherichia coli UTI89 3993544 YP_544085.1 CDS deoB NC_007946.1 5043297 5044520 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5043297..5044520 Escherichia coli UTI89 3993545 YP_544086.2 CDS deoD NC_007946.1 5044577 5045296 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5044577..5045296 Escherichia coli UTI89 3993546 YP_544087.1 CDS yjjJ NC_007946.1 5045463 5046794 D hypothetical protein 5045463..5046794 Escherichia coli UTI89 3993547 YP_544088.1 CDS lplA NC_007946.1 5046795 5047811 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(5046795..5047811) Escherichia coli UTI89 3993548 YP_544089.1 CDS smp NC_007946.1 5047839 5048483 R hypothetical protein complement(5047839..5048483) Escherichia coli UTI89 3993549 YP_544090.2 CDS serB NC_007946.1 5048589 5049557 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5048589..5049557 Escherichia coli UTI89 3993550 YP_544091.1 CDS radA NC_007946.1 5049558 5050988 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5049558..5050988 Escherichia coli UTI89 3993551 YP_544092.1 CDS nadR NC_007946.1 5050988 5052241 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5050988..5052241 Escherichia coli UTI89 3993552 YP_544093.1 CDS UTI89_C5162 NC_007946.1 5052255 5052665 D hypothetical protein 5052255..5052665 Escherichia coli UTI89 3993553 YP_544094.1 CDS UTI89_C5163 NC_007946.1 5052667 5052951 D hypothetical protein 5052667..5052951 Escherichia coli UTI89 3993554 YP_544095.1 CDS yjjK NC_007946.1 5053007 5054674 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(5053007..5054674) Escherichia coli UTI89 3993555 YP_544096.1 CDS slt NC_007946.1 5054881 5056818 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5054881..5056818 Escherichia coli UTI89 3993556 YP_544097.1 CDS trpR NC_007946.1 5056908 5057234 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5056908..5057234 Escherichia coli UTI89 3993557 YP_544098.1 CDS yjjX NC_007946.1 5057307 5057843 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(5057307..5057843) Escherichia coli UTI89 3993558 YP_544099.1 CDS gpmB NC_007946.1 5057886 5058533 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5057886..5058533 Escherichia coli UTI89 3993559 YP_544100.1 CDS rob NC_007946.1 5058530 5059399 R right origin-binding protein complement(5058530..5059399) Escherichia coli UTI89 3990249 YP_544101.1 CDS creA NC_007946.1 5059610 5060083 D hypothetical protein 5059610..5060083 Escherichia coli UTI89 3990250 YP_544102.1 CDS creB NC_007946.1 5060096 5060785 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5060096..5060785 Escherichia coli UTI89 3990251 YP_544103.1 CDS creC NC_007946.1 5060785 5062209 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5060785..5062209 Escherichia coli UTI89 3990252 YP_544104.1 CDS creD NC_007946.1 5062267 5063619 D hypothetical protein 5062267..5063619 Escherichia coli UTI89 3990253 YP_544105.1 CDS arcA NC_007946.1 5063679 5064395 R two-component response regulator complement(5063679..5064395) Escherichia coli UTI89 3990254 YP_544106.1 CDS yjjY NC_007946.1 5064491 5064631 D hypothetical protein 5064491..5064631 Escherichia coli UTI89 3990255 YP_544107.1 CDS lasT NC_007946.1 5065010 5065717 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5065010..5065717 Escherichia coli UTI89 3990256 UTI89_C0219 tRNA ileV NC_007946.1 230134 230207 D tRNA-Ile 230134..230207 Escherichia coli UTI89 3994579 UTI89_C0220 tRNA alaV NC_007946.1 230253 230325 D tRNA-Ala 230253..230325 Escherichia coli UTI89 3994580 UTI89_C0225 tRNA aspU NC_007946.1 233676 233749 D tRNA-Asp 233676..233749 Escherichia coli UTI89 3994585 UTI89_C0235 tRNA aspV NC_007946.1 241899 241972 D tRNA-Asp 241899..241972 Escherichia coli UTI89 3992092 UTI89_C0285 tRNA thrW NC_007946.1 295065 295137 D tRNA-Thr 295065..295137 Escherichia coli UTI89 3993775 UTI89_C0294 tRNA UTI89_C0294 NC_007946.1 305699 305771 D tRNA-Thr 305699..305771 Escherichia coli UTI89 3993784 UTI89_C0561 tRNA argU NC_007946.1 569030 569103 D tRNA-Arg 569030..569103 Escherichia coli UTI89 3993761 UTI89_C0661 tRNA glnX NC_007946.1 671218 671289 R tRNA-Gln complement(671218..671289) Escherichia coli UTI89 3991396 UTI89_C0662 tRNA glnV NC_007946.1 671330 671401 R tRNA-Gln complement(671330..671401) Escherichia coli UTI89 3991397 UTI89_C0663 tRNA metU NC_007946.1 671453 671526 R tRNA-Met complement(671453..671526) Escherichia coli UTI89 3991398 UTI89_C0664 tRNA glnW NC_007946.1 671545 671616 R tRNA-Gln complement(671545..671616) Escherichia coli UTI89 3991399 UTI89_C0665 tRNA glnU NC_007946.1 671654 671725 R tRNA-Gln complement(671654..671725) Escherichia coli UTI89 3991400 UTI89_C0666 tRNA leuW NC_007946.1 671752 671833 R tRNA-Leu complement(671752..671833) Escherichia coli UTI89 3991401 UTI89_C0667 tRNA metT NC_007946.1 671847 671920 R tRNA-Met complement(671847..671920) Escherichia coli UTI89 3990330 UTI89_C0740 tRNA lysT NC_007946.1 744282 744354 D tRNA-Lys 744282..744354 Escherichia coli UTI89 3993480 UTI89_C0741 tRNA valT NC_007946.1 744393 744465 D tRNA-Val 744393..744465 Escherichia coli UTI89 3993481 UTI89_C0742 tRNA lysW NC_007946.1 744471 744543 D tRNA-Lys 744471..744543 Escherichia coli UTI89 3991519 UTI89_C0743 tRNA valZ NC_007946.1 744598 744670 D tRNA-Val 744598..744670 Escherichia coli UTI89 3991520 UTI89_C0744 tRNA lysY NC_007946.1 744677 744749 D tRNA-Lys 744677..744749 Escherichia coli UTI89 3991521 UTI89_C0745 tRNA lysZ NC_007946.1 744801 744873 D tRNA-Lys 744801..744873 Escherichia coli UTI89 3991522 UTI89_C0746 tRNA lysQ NC_007946.1 744910 744982 D tRNA-Lys 744910..744982 Escherichia coli UTI89 3991523 UTI89_C0897 tRNA serW NC_007946.1 895679 895763 R tRNA-Ser complement(895679..895763) Escherichia coli UTI89 3993069 UTI89_C1039 tRNA serT NC_007946.1 1028950 1029034 R tRNA-Ser complement(1028950..1029034) Escherichia coli UTI89 3993133 UTI89_C1126 tRNA UTI89_C1126 NC_007946.1 1120468 1120541 D tRNA-Arg 1120468..1120541 Escherichia coli UTI89 3993373 UTI89_C1153 tRNA serX NC_007946.1 1142535 1142619 R tRNA-Ser complement(1142535..1142619) Escherichia coli UTI89 3994167 UTI89_C1426 tRNA tyrV NC_007946.1 1362337 1362418 R tRNA-Tyr complement(1362337..1362418) Escherichia coli UTI89 3994569 UTI89_C1427 tRNA tyrT NC_007946.1 1362455 1362536 R tRNA-Tyr complement(1362455..1362536) Escherichia coli UTI89 3994570 UTI89_C1482 tRNA ileY NC_007946.1 1404628 1404700 D tRNA-Ile 1404628..1404700 Escherichia coli UTI89 3990269 UTI89_C1483 tRNA UTI89_C1483 NC_007946.1 1404801 1404874 D tRNA-Arg 1404801..1404874 Escherichia coli UTI89 3990270 UTI89_C1856 tRNA valV NC_007946.1 1782194 1782267 D tRNA-Val 1782194..1782267 Escherichia coli UTI89 3991665 UTI89_C1857 tRNA valW NC_007946.1 1782275 1782348 D tRNA-Val 1782275..1782348 Escherichia coli UTI89 3993907 UTI89_C2110 tRNA leuZ NC_007946.1 2015566 2015649 R tRNA-Leu complement(2015566..2015649) Escherichia coli UTI89 3993198 UTI89_C2111 tRNA cysT NC_007946.1 2015665 2015735 R tRNA-Cys complement(2015665..2015735) Escherichia coli UTI89 3993199 UTI89_C2112 tRNA glyW NC_007946.1 2015792 2015864 R tRNA-Gly complement(2015792..2015864) Escherichia coli UTI89 3993200 UTI89_C2174 tRNA serU NC_007946.1 2068722 2068808 R tRNA-Ser complement(2068722..2068808) Escherichia coli UTI89 3992553 UTI89_C2176 tRNA asnT NC_007946.1 2069800 2069872 D tRNA-Asn 2069800..2069872 Escherichia coli UTI89 3992555 UTI89_C2198 tRNA asnW NC_007946.1 2109697 2109769 R tRNA-Asn complement(2109697..2109769) Escherichia coli UTI89 3994074 UTI89_C2200 tRNA asnU NC_007946.1 2111515 2111587 D tRNA-Asn 2111515..2111587 Escherichia coli UTI89 3994076 UTI89_C2203 tRNA asnV NC_007946.1 2113924 2113996 D tRNA-Asn 2113924..2113996 Escherichia coli UTI89 3991632 UTI89_C2467 tRNA proL NC_007946.1 2426261 2426334 D tRNA-Pro 2426261..2426334 Escherichia coli UTI89 3990400 UTI89_C2633 tRNA argW NC_007946.1 2597297 2597368 D tRNA-Arg 2597297..2597368 Escherichia coli UTI89 3991803 UTI89_C2727 tRNA alaX NC_007946.1 2677965 2678037 R tRNA-Ala complement(2677965..2678037) Escherichia coli UTI89 3991689 UTI89_C2728 tRNA alaW NC_007946.1 2678080 2678152 R tRNA-Ala complement(2678080..2678152) Escherichia coli UTI89 3991690 UTI89_C2732 tRNA valU NC_007946.1 2680851 2680923 D tRNA-Val 2680851..2680923 Escherichia coli UTI89 3991694 UTI89_C2733 tRNA valX NC_007946.1 2680971 2681043 D tRNA-Val 2680971..2681043 Escherichia coli UTI89 3991695 UTI89_C2734 tRNA valY NC_007946.1 2681093 2681165 D tRNA-Val 2681093..2681165 Escherichia coli UTI89 3991696 UTI89_C2735 tRNA lysV NC_007946.1 2681173 2681245 D tRNA-Lys 2681173..2681245 Escherichia coli UTI89 3991697 UTI89_C2921 tRNA gltW NC_007946.1 2873659 2873731 R tRNA-Glu complement(2873659..2873731) Escherichia coli UTI89 3992229 UTI89_C3053 tRNA argZ NC_007946.1 2976587 2976660 R tRNA-Arg complement(2976587..2976660) Escherichia coli UTI89 3990588 UTI89_C3054 tRNA argY NC_007946.1 2976727 2976800 R tRNA-Arg complement(2976727..2976800) Escherichia coli UTI89 3990589 UTI89_C3055 tRNA argV NC_007946.1 2976868 2976941 R tRNA-Arg complement(2976868..2976941) Escherichia coli UTI89 3990590 UTI89_C3056 tRNA serV NC_007946.1 2976948 2977037 R tRNA-Ser complement(2976948..2977037) Escherichia coli UTI89 3990591 UTI89_C3187 tRNA metZ NC_007946.1 3101730 3101803 D tRNA-Met 3101730..3101803 Escherichia coli UTI89 3990287 UTI89_C3188 tRNA metW NC_007946.1 3101840 3101913 D tRNA-Met 3101840..3101913 Escherichia coli UTI89 3990288 UTI89_C3189 tRNA metV NC_007946.1 3101950 3102023 D tRNA-Met 3101950..3102023 Escherichia coli UTI89 3990289 UTI89_C3249 tRNA glyU NC_007946.1 3177834 3177904 R tRNA-Gly complement(3177834..3177904) Escherichia coli UTI89 3994155 UTI89_C3359 tRNA pheV NC_007946.1 3287922 3287994 D tRNA-Phe 3287922..3287994 Escherichia coli UTI89 3992925 UTI89_C3507 tRNA ileX NC_007946.1 3443408 3443480 D tRNA-Ile 3443408..3443480 Escherichia coli UTI89 3992149 UTI89_C3603 tRNA metY NC_007946.1 3538051 3538124 R tRNA-Met complement(3538051..3538124) Escherichia coli UTI89 3994750 UTI89_C3606 tRNA leuU NC_007946.1 3541905 3541988 R tRNA-Leu complement(3541905..3541988) Escherichia coli UTI89 3994753 UTI89_C3715 tRNA thrV NC_007946.1 3641374 3641446 R tRNA-Thr complement(3641374..3641446) Escherichia coli UTI89 3991340 UTI89_C3720 tRNA alaU NC_007946.1 3644763 3644835 R tRNA-Ala complement(3644763..3644835) Escherichia coli UTI89 3991345 UTI89_C3721 tRNA ileU NC_007946.1 3644881 3644954 R tRNA-Ile complement(3644881..3644954) Escherichia coli UTI89 3991346 UTI89_C3796 tRNA UTI89_C3796 NC_007946.1 3689284 3689356 R tRNA-Thr complement(3689284..3689356) Escherichia coli UTI89 3993459 UTI89_C3797 tRNA UTI89_C3797 NC_007946.1 3689366 3689437 R tRNA-Gly complement(3689366..3689437) Escherichia coli UTI89 3993460 UTI89_C3798 tRNA UTI89_C3798 NC_007946.1 3689557 3689638 R tRNA-Tyr complement(3689557..3689638) Escherichia coli UTI89 3993461 UTI89_C3799 tRNA UTI89_C3799 NC_007946.1 3689650 3689722 R tRNA-Thr complement(3689650..3689722) Escherichia coli UTI89 3993462 UTI89_C3810 tRNA UTI89_C3810 NC_007946.1 3696502 3696574 R tRNA-Glu complement(3696502..3696574) Escherichia coli UTI89 3990856 UTI89_C4085 tRNA proK NC_007946.1 3975878 3975951 R tRNA-Pro complement(3975878..3975951) Escherichia coli UTI89 3989643 UTI89_C4211 tRNA selC NC_007946.1 4101848 4101938 D tRNA-Sec 4101848..4101938 Escherichia coli UTI89 3991488 UTI89_C4313 tRNA gltU NC_007946.1 4204303 4204375 D tRNA-Glu 4204303..4204375 Escherichia coli UTI89 3994325 UTI89_C4318 tRNA aspT NC_007946.1 4207740 4207813 D tRNA-Asp 4207740..4207813 Escherichia coli UTI89 3994025 UTI89_C4319 tRNA trpT NC_007946.1 4207825 4207897 D tRNA-Trp 4207825..4207897 Escherichia coli UTI89 3994026 UTI89_C4354 tRNA argX NC_007946.1 4242369 4242442 D tRNA-Arg 4242369..4242442 Escherichia coli UTI89 3992510 UTI89_C4355 tRNA hisR NC_007946.1 4242504 4242576 D tRNA-His 4242504..4242576 Escherichia coli UTI89 3992511 UTI89_C4356 tRNA leuT NC_007946.1 4242600 4242683 D tRNA-Leu 4242600..4242683 Escherichia coli UTI89 3992512 UTI89_C4357 tRNA proM NC_007946.1 4242729 4242802 D tRNA-Pro 4242729..4242802 Escherichia coli UTI89 3992513 UTI89_C4438 tRNA ileT NC_007946.1 4323468 4323541 D tRNA-Ile 4323468..4323541 Escherichia coli UTI89 3993844 UTI89_C4439 tRNA alaT NC_007946.1 4323587 4323659 D tRNA-Ala 4323587..4323659 Escherichia coli UTI89 3993845 UTI89_C4565 tRNA gltT NC_007946.1 4457994 4458066 D tRNA-Glu 4457994..4458066 Escherichia coli UTI89 3994355 UTI89_C4731 tRNA pheU NC_007946.1 4634666 4634738 R tRNA-Phe complement(4634666..4634738) Escherichia coli UTI89 3991034 UTI89_C4763 tRNA glyV NC_007946.1 4664172 4664244 D tRNA-Gly 4664172..4664244 Escherichia coli UTI89 3991011 UTI89_C4764 tRNA glyX NC_007946.1 4664284 4664356 D tRNA-Gly 4664284..4664356 Escherichia coli UTI89 3991012 UTI89_C4765 tRNA glyY NC_007946.1 4664395 4664467 D tRNA-Gly 4664395..4664467 Escherichia coli UTI89 3990881 UTI89_C4877 tRNA leuX NC_007946.1 4778112 4778193 D tRNA-Leu 4778112..4778193 Escherichia coli UTI89 3991162 UTI89_C5075 tRNA UTI89_C5075 NC_007946.1 4983852 4983935 R tRNA-Leu complement(4983852..4983935) Escherichia coli UTI89 3992069 UTI89_C5076 tRNA leuP NC_007946.1 4983973 4984056 R tRNA-Leu complement(4983973..4984056) Escherichia coli UTI89 3992070 UTI89_C5077 tRNA leuQ NC_007946.1 4984088 4984171 R tRNA-Leu complement(4984088..4984171) Escherichia coli UTI89 3992071 UTI89_C0217 rRNA rrsH NC_007946.1 228524 230065 D 16S ribosomal RNA 228524..230065 Escherichia coli UTI89 3994577 UTI89_C0221 rRNA rrlH NC_007946.1 230503 233406 D 23S ribosomal RNA 230503..233406 Escherichia coli UTI89 3994581 UTI89_C0224 rRNA rrfH NC_007946.1 233505 233624 D 5S ribosomal RNA 233505..233624 Escherichia coli UTI89 3994584 UTI89_C2917 rRNA rrfG NC_007946.1 2870341 2870460 R 5S ribosomal RNA complement(2870341..2870460) Escherichia coli UTI89 3992225 UTI89_C2918 rRNA rrlG NC_007946.1 2870559 2873462 R 23S ribosomal RNA complement(2870559..2873462) Escherichia coli UTI89 3992226 UTI89_C2922 rRNA rrsG NC_007946.1 2873817 2875358 R 16S ribosomal RNA complement(2873817..2875358) Escherichia coli UTI89 3992230 UTI89_C3714 rRNA rrfF NC_007946.1 3641214 3641333 R 5S ribosomal RNA complement(3641214..3641333) Escherichia coli UTI89 3991339 UTI89_C3716 rRNA rrfD NC_007946.1 3641459 3641578 R 5S ribosomal RNA complement(3641459..3641578) Escherichia coli UTI89 3991341 UTI89_C3717 rRNA rrlD NC_007946.1 3641673 3644576 R 23S ribosomal RNA complement(3641673..3644576) Escherichia coli UTI89 3991342 UTI89_C3722 rRNA rrsD NC_007946.1 3645023 3646564 R 16S ribosomal RNA complement(3645023..3646564) Escherichia coli UTI89 3991347 UTI89_C3806 rRNA rrfE NC_007946.1 3693188 3693307 R 5S ribosomal RNA complement(3693188..3693307) Escherichia coli UTI89 3990852 UTI89_C3807 rRNA rrlE NC_007946.1 3693402 3696305 R 23S ribosomal RNA complement(3693402..3696305) Escherichia coli UTI89 3990853 UTI89_C3811 rRNA rrsE NC_007946.1 3696660 3698201 R 16S ribosomal RNA complement(3696660..3698201) Escherichia coli UTI89 3990857 UTI89_C4311 rRNA rrsC NC_007946.1 4202676 4204217 D 16S ribosomal RNA 4202676..4204217 Escherichia coli UTI89 3994323 UTI89_C4314 rRNA rrlC NC_007946.1 4204572 4207475 D 23S ribosomal RNA 4204572..4207475 Escherichia coli UTI89 3994326 UTI89_C4317 rRNA rrfC NC_007946.1 4207569 4207688 D 5S ribosomal RNA 4207569..4207688 Escherichia coli UTI89 3994024 UTI89_C4436 rRNA rrsA NC_007946.1 4321858 4323399 D 16S ribosomal RNA 4321858..4323399 Escherichia coli UTI89 3993842 UTI89_C4440 rRNA rrlA NC_007946.1 4323846 4326749 D 23S ribosomal RNA 4323846..4326749 Escherichia coli UTI89 3993846 UTI89_C4442 rRNA rrfA NC_007946.1 4326843 4326962 D 5S ribosomal RNA 4326843..4326962 Escherichia coli UTI89 3992600 UTI89_C4563 rRNA rrsB NC_007946.1 4456367 4457908 D 16S ribosomal RNA 4456367..4457908 Escherichia coli UTI89 3994353 UTI89_C4566 rRNA rrlB NC_007946.1 4458263 4461166 D 23S ribosomal RNA 4458263..4461166 Escherichia coli UTI89 3994356 UTI89_C4569 rRNA rrfB NC_007946.1 4461265 4461384 D 5S ribosomal RNA 4461265..4461384 Escherichia coli UTI89 3994359