-- dump date 20140619_091242 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_538600.1 91206246 3996368 1..591 1 NC_007941.1 hypothetical protein 591 3996368 UTI89_P001 Escherichia coli UTI89 hypothetical protein YP_538600.1 1 D 364106 CDS YP_538601.1 91206247 3996369 831..1091 1 NC_007941.1 replication protein 1091 repB 3996369 repB Escherichia coli UTI89 replication protein YP_538601.1 831 D 364106 CDS YP_538602.1 91206248 3996370 1324..1398 1 NC_007941.1 RepA6; leader peptide RepL 1398 3996370 UTI89_P003 Escherichia coli UTI89 leader peptide RepL YP_538602.1 1324 D 364106 CDS YP_538603.1 91206249 3996371 1391..2248 1 NC_007941.1 RepA; replication protein 2248 repA1 3996371 repA1 Escherichia coli UTI89 replication protein YP_538603.1 1391 D 364106 CDS YP_538604.1 91206250 3996372 complement(3238..3831) 1 NC_007941.1 putative transposase 3831 3996372 UTI89_P005 Escherichia coli UTI89 putative transposase YP_538604.1 3238 R 364106 CDS YP_538605.1 91206251 3996373 3292..4008 1 NC_007941.1 tnIS26; transposase for IS26 4008 3996373 UTI89_P006 Escherichia coli UTI89 transposase for IS26 YP_538605.1 3292 D 364106 CDS YP_538606.1 91206252 3996374 4056..4265 1 NC_007941.1 secreted copper-sensitivity suppressor C 4265 scsC 3996374 scsC Escherichia coli UTI89 secreted copper-sensitivity suppressor C YP_538606.1 4056 D 364106 CDS YP_538607.1 91206253 3996375 4255..4761 1 NC_007941.1 secreted copper-sensitivity suppressor D 4761 scsD 3996375 scsD Escherichia coli UTI89 secreted copper-sensitivity suppressor D YP_538607.1 4255 D 364106 CDS YP_538608.1 91206254 3996376 4998..5759 1 NC_007941.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 5759 3996376 UTI89_P009 Escherichia coli UTI89 Na(+)-translocating NADH-quinone reductase subunit C YP_538608.1 4998 D 364106 CDS YP_538609.1 91206255 3996377 6106..7992 1 NC_007941.1 hypothetical protein 7992 3996377 UTI89_P010 Escherichia coli UTI89 hypothetical protein YP_538609.1 6106 D 364106 CDS YP_538610.1 91206256 3996378 8033..8560 1 NC_007941.1 hypothetical protein 8560 3996378 UTI89_P011 Escherichia coli UTI89 hypothetical protein YP_538610.1 8033 D 364106 CDS YP_538611.1 91206257 3996379 8664..10043 1 NC_007941.1 hypothetical protein 10043 3996379 UTI89_P012 Escherichia coli UTI89 hypothetical protein YP_538611.1 8664 D 364106 CDS YP_538612.1 91206258 3996380 10046..11329 1 NC_007941.1 hypothetical protein 11329 3996380 UTI89_P013 Escherichia coli UTI89 hypothetical protein YP_538612.1 10046 D 364106 CDS YP_538613.1 91206259 3996381 11319..12449 1 NC_007941.1 putative integral membrane protein 12449 3996381 UTI89_P014 Escherichia coli UTI89 putative integral membrane protein YP_538613.1 11319 D 364106 CDS YP_538614.1 91206260 3996382 12454..13149 1 NC_007941.1 ABC transporter, ATP-binding protein 13149 3996382 UTI89_P015 Escherichia coli UTI89 ABC transporter, ATP-binding protein YP_538614.1 12454 D 364106 CDS YP_538615.1 91206261 3996383 13136..13621 1 NC_007941.1 putative thioredoxin-family protein 13621 3996383 UTI89_P016 Escherichia coli UTI89 putative thioredoxin-family protein YP_538615.1 13136 D 364106 CDS YP_538616.1 91206262 3996384 13751..14131 1 NC_007941.1 hypothetical protein 14131 3996384 UTI89_P017 Escherichia coli UTI89 hypothetical protein YP_538616.1 13751 D 364106 CDS YP_538617.1 91206263 3996385 15493..15918 1 NC_007941.1 hypothetical protein 15918 3996385 UTI89_P018 Escherichia coli UTI89 hypothetical protein YP_538617.1 15493 D 364106 CDS YP_538618.1 91206264 3996386 15809..16204 1 NC_007941.1 hypothetical protein 16204 3996386 UTI89_P019 Escherichia coli UTI89 hypothetical protein YP_538618.1 15809 D 364106 CDS YP_538619.1 91206265 3996387 16439..16855 1 NC_007941.1 hypothetical protein 16855 3996387 UTI89_P020 Escherichia coli UTI89 hypothetical protein YP_538619.1 16439 D 364106 CDS YP_538620.1 91206266 3996388 complement(16610..16936) 1 NC_007941.1 putative transposase OrfA protein of insertion sequence IS629 16936 3996388 UTI89_P021 Escherichia coli UTI89 putative transposase OrfA protein of insertion sequence IS629 YP_538620.1 16610 R 364106 CDS YP_538621.1 91206267 3996389 17038..17298 1 NC_007941.1 hypothetical protein 17298 3996389 UTI89_P022 Escherichia coli UTI89 hypothetical protein YP_538621.1 17038 D 364106 CDS YP_538622.1 91206268 3996390 17295..17804 1 NC_007941.1 hypothetical protein 17804 3996390 UTI89_P023 Escherichia coli UTI89 hypothetical protein YP_538622.1 17295 D 364106 CDS YP_538623.1 91206269 3996391 complement(17824..18132) 1 NC_007941.1 hypothetical protein 18132 3996391 UTI89_P024 Escherichia coli UTI89 hypothetical protein YP_538623.1 17824 R 364106 CDS YP_538624.1 91206270 3996392 18200..18322 1 NC_007941.1 hypothetical protein 18322 3996392 UTI89_P025 Escherichia coli UTI89 hypothetical protein YP_538624.1 18200 D 364106 CDS YP_538625.1 91206271 3996393 18300..18635 1 NC_007941.1 immunity protein 18635 3996393 UTI89_P026 Escherichia coli UTI89 immunity protein YP_538625.1 18300 D 364106 CDS YP_538626.1 91206272 3996394 21105..21980 1 NC_007941.1 putative inner membrane lipoprotein 21980 cjrA 3996394 cjrA Escherichia coli UTI89 putative inner membrane lipoprotein YP_538626.1 21105 D 364106 CDS YP_538627.1 91206273 3996395 21988..22764 1 NC_007941.1 putative periplasmic colicin Js sensitivity protein CjrB 22764 cjrB 3996395 cjrB Escherichia coli UTI89 putative periplasmic colicin Js sensitivity protein CjrB YP_538627.1 21988 D 364106 CDS YP_538628.1 91206274 3996396 22933..25194 1 NC_007941.1 putative outer membrane colicin Js receptor 25194 cjrC 3996396 cjrC Escherichia coli UTI89 putative outer membrane colicin Js receptor YP_538628.1 22933 D 364106 CDS YP_538629.1 91206275 3996397 25164..26438 1 NC_007941.1 enterotoxin TieB protein 26438 senB 3996397 senB Escherichia coli UTI89 enterotoxin TieB protein YP_538629.1 25164 D 364106 CDS YP_538630.1 91206276 3996398 complement(26961..27227) 1 NC_007941.1 transposase 27227 3996398 UTI89_P031 Escherichia coli UTI89 transposase YP_538630.1 26961 R 364106 CDS YP_538631.1 91206277 3996399 27292..27618 1 NC_007941.1 hypothetical protein 27618 3996399 UTI89_P032 Escherichia coli UTI89 hypothetical protein YP_538631.1 27292 D 364106 CDS YP_538632.1 91206278 3996400 complement(27760..28515) 1 NC_007941.1 insertion sequence ATP-binding protein 28515 3996400 UTI89_P033 Escherichia coli UTI89 insertion sequence ATP-binding protein YP_538632.1 27760 R 364106 CDS YP_538633.1 91206279 3996401 complement(28512..30011) 1 NC_007941.1 hypothetical protein 30011 3996401 UTI89_P034 Escherichia coli UTI89 hypothetical protein YP_538633.1 28512 R 364106 CDS YP_538634.1 91206280 3996402 complement(30440..30811) 1 NC_007941.1 hypothetical protein 30811 3996402 UTI89_P035 Escherichia coli UTI89 hypothetical protein YP_538634.1 30440 R 364106 CDS YP_538635.1 91206281 3996403 complement(30726..31151) 1 NC_007941.1 hypothetical protein 31151 3996403 UTI89_P036 Escherichia coli UTI89 hypothetical protein YP_538635.1 30726 R 364106 CDS YP_538636.1 91206282 3996404 31120..32628 1 NC_007941.1 hypothetical protein 32628 3996404 UTI89_P037 Escherichia coli UTI89 hypothetical protein YP_538636.1 31120 D 364106 CDS YP_538637.1 91206283 3996405 33130..33534 1 NC_007941.1 hypothetical protein 33534 3996405 UTI89_P038 Escherichia coli UTI89 hypothetical protein YP_538637.1 33130 D 364106 CDS YP_538638.1 91206284 3996406 33531..33878 1 NC_007941.1 hypothetical protein 33878 3996406 UTI89_P039 Escherichia coli UTI89 hypothetical protein YP_538638.1 33531 D 364106 CDS YP_538639.1 91206285 3996407 34958..35980 1 NC_007941.1 putative transposase 35980 3996407 UTI89_P040 Escherichia coli UTI89 putative transposase YP_538639.1 34958 D 364106 CDS YP_538640.1 91206286 3996408 35977..36759 1 NC_007941.1 transposase/IS protein 36759 3996408 UTI89_P041 Escherichia coli UTI89 transposase/IS protein YP_538640.1 35977 D 364106 CDS YP_538641.1 91206287 3996409 complement(37498..38286) 1 NC_007941.1 hypothetical protein 38286 3996409 UTI89_P042 Escherichia coli UTI89 hypothetical protein YP_538641.1 37498 R 364106 CDS YP_538642.1 91206288 3996410 complement(38296..40266) 1 NC_007941.1 putative hemin receptor 40266 3996410 UTI89_P043 Escherichia coli UTI89 putative hemin receptor YP_538642.1 38296 R 364106 CDS YP_538643.3 229577730 3996411 40503..40913 1 NC_007941.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 40913 3996411 UTI89_P044 Escherichia coli UTI89 insertion sequence 2 OrfA protein YP_538643.3 40503 D 364106 CDS YP_538644.1 91206290 3996412 41509..41781 1 NC_007941.1 hypothetical protein 41781 pixB 3996412 pixB Escherichia coli UTI89 hypothetical protein YP_538644.1 41509 D 364106 CDS YP_538645.1 91206291 3996413 44164..44352 1 NC_007941.1 hypothetical serine-threonine protein kinase 44352 3996413 UTI89_P046 Escherichia coli UTI89 hypothetical serine-threonine protein kinase YP_538645.1 44164 D 364106 CDS YP_538646.1 91206292 3996414 44334..44462 1 NC_007941.1 hypothetical protein 44462 3996414 UTI89_P047 Escherichia coli UTI89 hypothetical protein YP_538646.1 44334 D 364106 CDS YP_538647.1 91206293 3996415 44473..45213 1 NC_007941.1 site-specific recombinase 45213 int 3996415 int Escherichia coli UTI89 site-specific recombinase YP_538647.1 44473 D 364106 CDS YP_538648.1 91206294 3996416 complement(44902..45219) 1 NC_007941.1 hypothetical protein 45219 3996416 UTI89_P049 Escherichia coli UTI89 hypothetical protein YP_538648.1 44902 R 364106 CDS YP_538649.1 91206295 3996417 complement(45456..46433) 1 NC_007941.1 replication protein RepFIB (P307 replicon) 46433 3996417 UTI89_P050 Escherichia coli UTI89 replication protein RepFIB (P307 replicon) YP_538649.1 45456 R 364106 CDS YP_538650.1 91206296 3996418 46171..46500 1 NC_007941.1 hypothetical protein 46500 3996418 UTI89_P051 Escherichia coli UTI89 hypothetical protein YP_538650.1 46171 D 364106 CDS YP_538651.1 91206297 3996419 complement(47608..48249) 1 NC_007941.1 hypothetical protein 48249 ydiA 3996419 ydiA Escherichia coli UTI89 hypothetical protein YP_538651.1 47608 R 364106 CDS YP_538652.1 91206298 3996420 48236..48466 1 NC_007941.1 hypothetical protein 48466 3996420 UTI89_P053 Escherichia coli UTI89 hypothetical protein YP_538652.1 48236 D 364106 CDS YP_538653.1 91206299 3996421 complement(49212..49379) 1 NC_007941.1 hypothetical protein 49379 3996421 UTI89_P054 Escherichia coli UTI89 hypothetical protein YP_538653.1 49212 R 364106 CDS YP_538654.1 91206300 3996422 complement(49706..49933) 1 NC_007941.1 hypothetical protein 49933 yeaA 3996422 yeaA Escherichia coli UTI89 hypothetical protein YP_538654.1 49706 R 364106 CDS YP_538655.1 91206301 3996423 50571..50789 1 NC_007941.1 plasmid maintenance protein CcdA 50789 ccdA 3996423 ccdA Escherichia coli UTI89 plasmid maintenance protein CcdA YP_538655.1 50571 D 364106 CDS YP_538656.1 91206302 3996424 50770..51096 1 NC_007941.1 controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 51096 ccdB 3996424 ccdB Escherichia coli UTI89 plasmid maintenance protein CcdB YP_538656.1 50770 D 364106 CDS YP_538657.1 91206303 3996425 51097..51906 1 NC_007941.1 resolvase 51906 rsvB 3996425 rsvB Escherichia coli UTI89 resolvase YP_538657.1 51097 D 364106 CDS YP_538658.1 91206304 3996426 complement(51100..51780) 1 NC_007941.1 hypothetical protein 51780 3996426 UTI89_P059 Escherichia coli UTI89 hypothetical protein YP_538658.1 51100 R 364106 CDS YP_538659.1 91206305 3996427 complement(52044..52319) 1 NC_007941.1 hypothetical protein 52319 3996427 UTI89_P060 Escherichia coli UTI89 hypothetical protein YP_538659.1 52044 R 364106 CDS YP_538660.1 91206306 3996428 complement(52313..52957) 1 NC_007941.1 hypothetical protein 52957 3996428 UTI89_P061 Escherichia coli UTI89 hypothetical protein YP_538660.1 52313 R 364106 CDS YP_538661.1 91206307 3996429 53186..54157 1 NC_007941.1 stable plasmid inheritance protein 54157 stbA 3996429 stbA Escherichia coli UTI89 stable plasmid inheritance protein YP_538661.1 53186 D 364106 CDS YP_538662.1 91206308 3996430 54162..54554 1 NC_007941.1 stable plasmid inheritance protein 54554 stbB 3996430 stbB Escherichia coli UTI89 stable plasmid inheritance protein YP_538662.1 54162 D 364106 CDS YP_538663.1 91206309 3996431 complement(55829..56266) 1 NC_007941.1 UV protection and mutation protein 56266 impA 3996431 impA Escherichia coli UTI89 UV protection and mutation protein YP_538663.1 55829 R 364106 CDS YP_538664.1 91206310 3996432 complement(56263..56511) 1 NC_007941.1 UV protection and mutation protein 56511 impC 3996432 impC Escherichia coli UTI89 UV protection and mutation protein YP_538664.1 56263 R 364106 CDS YP_538665.1 91206311 3996433 56646..57164 1 NC_007941.1 hypothetical protein 57164 3996433 UTI89_P066 Escherichia coli UTI89 hypothetical protein YP_538665.1 56646 D 364106 CDS YP_538666.1 91206312 3996434 57183..58403 1 NC_007941.1 transposase 58403 3996434 UTI89_P067 Escherichia coli UTI89 transposase YP_538666.1 57183 D 364106 CDS YP_538667.1 91206313 3996435 58515..58784 1 NC_007941.1 hypothetical protein 58784 3996435 UTI89_P068 Escherichia coli UTI89 hypothetical protein YP_538667.1 58515 D 364106 CDS YP_538668.1 91206314 3996436 58798..59652 1 NC_007941.1 hypothetical protein 59652 yccB 3996436 yccB Escherichia coli UTI89 hypothetical protein YP_538668.1 58798 D 364106 CDS YP_538669.1 91206315 3996437 complement(59646..60443) 1 NC_007941.1 IS21 putative ATP-binding protein 60443 istB 3996437 istB Escherichia coli UTI89 IS21 putative ATP-binding protein YP_538669.1 59646 R 364106 CDS YP_538670.1 91206316 3996438 complement(60443..61615) 1 NC_007941.1 transposase for insertion sequence element IS21 61615 istA 3996438 istA Escherichia coli UTI89 transposase for insertion sequence element IS21 YP_538670.1 60443 R 364106 CDS YP_538671.1 91206317 3996439 61466..61687 1 NC_007941.1 hypothetical protein 61687 3996439 UTI89_P072 Escherichia coli UTI89 hypothetical protein YP_538671.1 61466 D 364106 CDS YP_538672.1 91206318 3996440 61656..61859 1 NC_007941.1 hypothetical protein 61859 3996440 UTI89_P073 Escherichia coli UTI89 hypothetical protein YP_538672.1 61656 D 364106 CDS YP_538673.1 91206319 3996441 61856..62167 1 NC_007941.1 hypothetical protein 62167 yfbA 3996441 yfbA Escherichia coli UTI89 hypothetical protein YP_538673.1 61856 D 364106 CDS YP_538674.1 91206320 3996442 62243..62926 1 NC_007941.1 putative methylase 62926 3996442 UTI89_P075 Escherichia coli UTI89 putative methylase YP_538674.1 62243 D 364106 CDS YP_538675.1 91206321 3996443 62927..63148 1 NC_007941.1 hypothetical protein 63148 yfeB 3996443 yfeB Escherichia coli UTI89 hypothetical protein YP_538675.1 62927 D 364106 CDS YP_538676.1 91206322 3996444 63162..63596 1 NC_007941.1 hypothetical protein 63596 yfcB 3996444 yfcB Escherichia coli UTI89 hypothetical protein YP_538676.1 63162 D 364106 CDS YP_538677.1 91206323 3996445 63641..64411 1 NC_007941.1 hypothetical protein 64411 ycfA 3996445 ycfA Escherichia coli UTI89 hypothetical protein YP_538677.1 63641 D 364106 CDS YP_538678.1 91206324 3996446 64827..65252 1 NC_007941.1 hypothetical protein 65252 yciB 3996446 yciB Escherichia coli UTI89 hypothetical protein YP_538678.1 64827 D 364106 CDS YP_538679.1 91206325 3996447 65299..65721 1 NC_007941.1 hypothetical protein 65721 3996447 UTI89_P080 Escherichia coli UTI89 hypothetical protein YP_538679.1 65299 D 364106 CDS YP_538680.1 91206326 3996448 65718..65909 1 NC_007941.1 hypothetical protein 65909 3996448 UTI89_P081 Escherichia coli UTI89 hypothetical protein YP_538680.1 65718 D 364106 CDS YP_538681.1 91206327 3996449 65773..66156 1 NC_007941.1 hypothetical protein 66156 ycjB 3996449 ycjB Escherichia coli UTI89 hypothetical protein YP_538681.1 65773 D 364106 CDS YP_538682.1 91206328 3996450 complement(65886..66380) 1 NC_007941.1 hypothetical protein 66380 3996450 UTI89_P083 Escherichia coli UTI89 hypothetical protein YP_538682.1 65886 R 364106 CDS YP_538683.1 91206329 3996451 66029..66388 1 NC_007941.1 hypothetical protein 66388 3996451 UTI89_P084 Escherichia coli UTI89 hypothetical protein YP_538683.1 66029 D 364106 CDS YP_538684.1 91206330 3996452 complement(66356..66613) 1 NC_007941.1 hypothetical protein 66613 3996452 UTI89_P085 Escherichia coli UTI89 hypothetical protein YP_538684.1 66356 R 364106 CDS YP_538685.1 91206331 3996453 66872..67102 1 NC_007941.1 hypothetical protein 67102 3996453 UTI89_P086 Escherichia coli UTI89 hypothetical protein YP_538685.1 66872 D 364106 CDS YP_538686.1 91206332 3996454 complement(66890..67150) 1 NC_007941.1 hypothetical protein 67150 3996454 UTI89_P087 Escherichia coli UTI89 hypothetical protein YP_538686.1 66890 R 364106 CDS YP_538687.1 91206333 3996455 67154..68515 1 NC_007941.1 hypothetical protein 68515 ydbA 3996455 ydbA Escherichia coli UTI89 hypothetical protein YP_538687.1 67154 D 364106 CDS YP_538688.1 91206334 3996456 68562..69125 1 NC_007941.1 hypothetical protein 69125 3996456 UTI89_P089 Escherichia coli UTI89 hypothetical protein YP_538688.1 68562 D 364106 CDS YP_538689.1 91206335 3996457 complement(69211..69669) 1 NC_007941.1 hypothetical protein 69669 3996457 UTI89_P090 Escherichia coli UTI89 hypothetical protein YP_538689.1 69211 R 364106 CDS YP_538690.1 91206336 3996458 complement(69670..69906) 1 NC_007941.1 hypothetical protein 69906 3996458 UTI89_P091 Escherichia coli UTI89 hypothetical protein YP_538690.1 69670 R 364106 CDS YP_538691.1 91206337 3996459 69932..70498 1 NC_007941.1 single-stranded DNA-binding protein 70498 ssb 3996459 ssb Escherichia coli UTI89 single-stranded DNA-binding protein YP_538691.1 69932 D 364106 CDS YP_538692.1 91206338 3996460 70549..70788 1 NC_007941.1 hypothetical protein 70788 ydeA 3996460 ydeA Escherichia coli UTI89 hypothetical protein YP_538692.1 70549 D 364106 CDS YP_538693.3 229577731 3996461 70757..72805 1 NC_007941.1 hypothetical protein 72805 ycjA 3996461 ycjA Escherichia coli UTI89 hypothetical protein YP_538693.3 70757 D 364106 CDS YP_538694.1 91206340 3996462 72860..73294 1 NC_007941.1 plasmid SOS inhibition protein B 73294 psiB 3996462 psiB Escherichia coli UTI89 plasmid SOS inhibition protein B YP_538694.1 72860 D 364106 CDS YP_538695.1 91206341 3996463 73291..74010 1 NC_007941.1 PsiA; plasmid SOS inhibition protein A 74010 3996463 UTI89_P096 Escherichia coli UTI89 plasmid SOS inhibition protein A YP_538695.1 73291 D 364106 CDS YP_538696.1 91206342 3996464 74228..74440 1 NC_007941.1 Mok; similar to F leading maintenance protein C; modulator of post-segregation killing protein 74440 3996464 UTI89_P097 Escherichia coli UTI89 modulator of post-segregation killing protein YP_538696.1 74228 D 364106 CDS YP_538697.1 91206343 3996465 74286..74444 1 NC_007941.1 small toxic polypeptide 74444 flmA 3996465 flmA Escherichia coli UTI89 small toxic polypeptide YP_538697.1 74286 D 364106 CDS YP_538698.1 91206344 3996466 complement(75060..75296) 1 NC_007941.1 hypothetical protein 75296 3996466 UTI89_P099 Escherichia coli UTI89 hypothetical protein YP_538698.1 75060 R 364106 CDS YP_538699.1 91206345 3996467 75360..75647 1 NC_007941.1 hypothetical protein 75647 3996467 UTI89_P100 Escherichia coli UTI89 hypothetical protein YP_538699.1 75360 D 364106 CDS YP_538700.1 91206346 3996468 75766..76587 1 NC_007941.1 hypothetical protein 76587 3996468 UTI89_P101 Escherichia coli UTI89 hypothetical protein YP_538700.1 75766 D 364106 CDS YP_538701.1 91206347 3996469 complement(76883..77392) 1 NC_007941.1 lytic transglycosylase 77392 3996469 UTI89_P102 Escherichia coli UTI89 lytic transglycosylase YP_538701.1 76883 R 364106 CDS YP_538702.1 91206348 3996470 77816..78199 1 NC_007941.1 conjugal transfer protein TraM 78199 traM 3996470 traM Escherichia coli UTI89 conjugal transfer protein TraM YP_538702.1 77816 D 364106 CDS YP_538703.1 91206349 3996471 78333..79079 1 NC_007941.1 functional relaxosome complex initiator 79079 traJ 3996471 traJ Escherichia coli UTI89 functional relaxosome complex initiator YP_538703.1 78333 D 364106 CDS YP_538704.1 91206350 3996472 79173..79400 1 NC_007941.1 conjugal transfer protein TraY 79400 traY 3996472 traY Escherichia coli UTI89 conjugal transfer protein TraY YP_538704.1 79173 D 364106 CDS YP_538705.1 91206351 3996473 79434..79793 1 NC_007941.1 conjugal transfer pilin subunit TraA 79793 traA 3996473 traA Escherichia coli UTI89 conjugal transfer pilin subunit TraA YP_538705.1 79434 D 364106 CDS YP_538706.1 91206352 3996474 79808..80119 1 NC_007941.1 conjugal transfer pilus assembly protein TraL 80119 traL 3996474 traL Escherichia coli UTI89 conjugal transfer pilus assembly protein TraL YP_538706.1 79808 D 364106 CDS YP_538707.1 91206353 3996475 80141..80707 1 NC_007941.1 conjugal transfer pilus assembly protein TraE 80707 traE 3996475 traE Escherichia coli UTI89 conjugal transfer pilus assembly protein TraE YP_538707.1 80141 D 364106 CDS YP_538708.1 91206354 3996476 80694..81422 1 NC_007941.1 conjugal transfer protein TraK 81422 traK 3996476 traK Escherichia coli UTI89 conjugal transfer protein TraK YP_538708.1 80694 D 364106 CDS YP_538709.1 91206355 3996477 81422..82849 1 NC_007941.1 conjugal transfer pilus assembly protein TraB 82849 traB 3996477 traB Escherichia coli UTI89 conjugal transfer pilus assembly protein TraB YP_538709.1 81422 D 364106 CDS YP_538710.1 91206356 3996478 82839..83429 1 NC_007941.1 conjugal transfer protein TraP 83429 traP 3996478 traP Escherichia coli UTI89 conjugal transfer protein TraP YP_538710.1 82839 D 364106 CDS YP_538711.1 91206357 3996479 83368..83736 1 NC_007941.1 conjugal transfer protein TrbD 83736 trbD 3996479 trbD Escherichia coli UTI89 conjugal transfer protein TrbD YP_538711.1 83368 D 364106 CDS YP_538712.1 91206358 3996480 83978..84493 1 NC_007941.1 conjugal transfer protein TraV 84493 traV 3996480 traV Escherichia coli UTI89 conjugal transfer protein TraV YP_538712.1 83978 D 364106 CDS YP_538713.1 91206359 3996481 84628..84849 1 NC_007941.1 conjugal transfer protein TraR 84849 traR 3996481 traR Escherichia coli UTI89 conjugal transfer protein TraR YP_538713.1 84628 D 364106 CDS YP_538714.1 91206360 3996482 84842..85315 1 NC_007941.1 hypothetical protein 85315 yfiA 3996482 yfiA Escherichia coli UTI89 hypothetical protein YP_538714.1 84842 D 364106 CDS YP_538715.1 91206361 3996483 85395..85613 1 NC_007941.1 hypothetical protein 85613 3996483 UTI89_P116 Escherichia coli UTI89 hypothetical protein YP_538715.1 85395 D 364106 CDS YP_538716.1 91206362 3996484 85980..88610 1 NC_007941.1 similar to VirB4; conjugal transfer ATP-binding protein TraC 88610 traC 3996484 traC Escherichia coli UTI89 conjugal transfer ATP-binding protein TraC YP_538716.1 85980 D 364106 CDS YP_538717.1 91206363 3996485 88607..88993 1 NC_007941.1 conjugal transfer protein TrbI 88993 trbI 3996485 trbI Escherichia coli UTI89 conjugal transfer protein TrbI YP_538717.1 88607 D 364106 CDS YP_538718.1 91206364 3996486 88990..89622 1 NC_007941.1 conjugal transfer pilus assembly protein TraW 89622 traW 3996486 traW Escherichia coli UTI89 conjugal transfer pilus assembly protein TraW YP_538718.1 88990 D 364106 CDS YP_538719.1 91206365 3996487 89619..90611 1 NC_007941.1 conjugal transfer pilus assembly protein TraU 90611 traU 3996487 traU Escherichia coli UTI89 conjugal transfer pilus assembly protein TraU YP_538719.1 89619 D 364106 CDS YP_538720.1 91206366 3996488 90635..90946 1 NC_007941.1 hypothetical protein 90946 3996488 UTI89_P121 Escherichia coli UTI89 hypothetical protein YP_538720.1 90635 D 364106 CDS YP_538721.1 91206367 3996489 90955..91593 1 NC_007941.1 conjugal transfer pilus assembly protein TrbC 91593 trbC 3996489 trbC Escherichia coli UTI89 conjugal transfer pilus assembly protein TrbC YP_538721.1 90955 D 364106 CDS YP_538722.1 91206368 3996490 91590..93440 1 NC_007941.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 93440 traN 3996490 traN Escherichia coli UTI89 conjugal transfer mating pair stabilization protein TraN YP_538722.1 91590 D 364106 CDS YP_538723.1 91206369 3996491 93464..93724 1 NC_007941.1 conjugal transfer protein TrbE 93724 trbE 3996491 trbE Escherichia coli UTI89 conjugal transfer protein TrbE YP_538723.1 93464 D 364106 CDS YP_538724.1 91206370 3996492 93687..94460 1 NC_007941.1 type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal pilus assembly protein TraF 94460 traF 3996492 traF Escherichia coli UTI89 conjugal pilus assembly protein TraF YP_538724.1 93687 D 364106 CDS YP_538725.1 91206371 3996493 94474..94815 1 NC_007941.1 conjugal transfer protein TrbA 94815 trbA 3996493 trbA Escherichia coli UTI89 conjugal transfer protein TrbA YP_538725.1 94474 D 364106 CDS YP_538726.1 91206372 3996494 complement(94796..95131) 1 NC_007941.1 hypothetical protein 95131 artA 3996494 artA Escherichia coli UTI89 hypothetical protein YP_538726.1 94796 R 364106 CDS YP_538727.1 91206373 3996495 95212..95496 1 NC_007941.1 conjugal transfer pilin chaperone TraQ 95496 traQ 3996495 traQ Escherichia coli UTI89 conjugal transfer pilin chaperone TraQ YP_538727.1 95212 D 364106 CDS YP_538728.1 91206374 3996496 95483..96028 1 NC_007941.1 conjugal transfer protein TrbB 96028 trbB 3996496 trbB Escherichia coli UTI89 conjugal transfer protein TrbB YP_538728.1 95483 D 364106 CDS YP_538729.1 91206375 3996497 95958..96305 1 NC_007941.1 conjugal transfer protein TrbJ 96305 trbJ 3996497 trbJ Escherichia coli UTI89 conjugal transfer protein TrbJ YP_538729.1 95958 D 364106 CDS YP_538730.1 91206376 3996498 96253..96678 1 NC_007941.1 conjugal transfer protein TrbF 96678 trbF 3996498 trbF Escherichia coli UTI89 conjugal transfer protein TrbF YP_538730.1 96253 D 364106 CDS YP_538731.1 91206377 3996499 96656..98038 1 NC_007941.1 conjugal transfer pilus assembly protein TraH 98038 traH 3996499 traH Escherichia coli UTI89 conjugal transfer pilus assembly protein TraH YP_538731.1 96656 D 364106 CDS YP_538732.1 91206378 3996500 98035..100857 1 NC_007941.1 conjugal transfer mating pair stabilization protein TraG 100857 traG 3996500 traG Escherichia coli UTI89 conjugal transfer mating pair stabilization protein TraG YP_538732.1 98035 D 364106 CDS YP_538733.1 91206379 3996501 100873..101358 1 NC_007941.1 surface exclusion inner membrane protein 101358 traS 3996501 traS Escherichia coli UTI89 surface exclusion inner membrane protein YP_538733.1 100873 D 364106 CDS YP_538734.1 91206380 3996502 101407..102138 1 NC_007941.1 conjugal transfer surface exclusion protein TraT 102138 traT 3996502 traT Escherichia coli UTI89 conjugal transfer surface exclusion protein TraT YP_538734.1 101407 D 364106 CDS YP_538735.1 91206381 3996503 102296..103078 1 NC_007941.1 hypothetical protein 103078 yhfA 3996503 yhfA Escherichia coli UTI89 hypothetical protein YP_538735.1 102296 D 364106 CDS YP_538736.1 91206382 3996504 103129..105273 1 NC_007941.1 type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD 105273 traD 3996504 traD Escherichia coli UTI89 conjugal transfer protein TraD YP_538736.1 103129 D 364106 CDS YP_538737.1 91206383 3996505 105273..110543 1 NC_007941.1 cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer nickase/helicase TraI 110543 traI 3996505 traI Escherichia coli UTI89 conjugal transfer nickase/helicase TraI YP_538737.1 105273 D 364106 CDS YP_538738.1 91206384 3996506 complement(107306..107875) 1 NC_007941.1 hypothetical protein 107875 3996506 UTI89_P139 Escherichia coli UTI89 hypothetical protein YP_538738.1 107306 R 364106 CDS YP_538739.1 91206385 3996507 110506..111309 1 NC_007941.1 conjugal transfer pilus acetylation protein TraX 111309 traX 3996507 traX Escherichia coli UTI89 conjugal transfer pilus acetylation protein TraX YP_538739.1 110506 D 364106 CDS YP_538740.1 91206386 3996508 111368..112228 1 NC_007941.1 hypothetical protein 112228 3996508 UTI89_P141 Escherichia coli UTI89 hypothetical protein YP_538740.1 111368 D 364106 CDS YP_538741.1 91206387 3996509 112331..112891 1 NC_007941.1 conjugal transfer fertility inhibition protein FinO 112891 finO 3996509 finO Escherichia coli UTI89 conjugal transfer fertility inhibition protein FinO YP_538741.1 112331 D 364106 CDS YP_538742.1 91206388 3996510 113020..113232 1 NC_007941.1 hypothetical protein 113232 3996510 UTI89_P143 Escherichia coli UTI89 hypothetical protein YP_538742.1 113020 D 364106 CDS YP_538743.1 91206389 3996511 113465..113938 1 NC_007941.1 hypothetical protein 113938 3996511 UTI89_P144 Escherichia coli UTI89 hypothetical protein YP_538743.1 113465 D 364106 CDS YP_538744.1 91206390 3996512 113984..114193 1 NC_007941.1 putative regulator 114193 hmo 3996512 hmo Escherichia coli UTI89 putative regulator YP_538744.1 113984 D 364106 CDS YP_539042.1 91209056 3993026 190..255 1 NC_007946.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 255 thrL 3993026 thrL Escherichia coli UTI89 thr operon leader peptide YP_539042.1 190 D 364106 CDS YP_539043.1 91209057 3993027 336..2798 1 NC_007946.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2798 thrA 3993027 thrA Escherichia coli UTI89 bifunctional aspartokinase I/homoserine dehydrogenase I YP_539043.1 336 D 364106 CDS YP_539044.1 91209058 3993028 2800..3732 1 NC_007946.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3732 thrB 3993028 thrB Escherichia coli UTI89 homoserine kinase YP_539044.1 2800 D 364106 CDS YP_539045.1 91209059 3993029 3733..5019 1 NC_007946.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5019 thrC 3993029 thrC Escherichia coli UTI89 threonine synthase YP_539045.1 3733 D 364106 CDS YP_539046.1 91209060 3993030 5233..5529 1 NC_007946.1 hypothetical protein 5529 yaaX 3993030 yaaX Escherichia coli UTI89 hypothetical protein YP_539046.1 5233 D 364106 CDS YP_539047.1 91209061 3993031 complement(5309..5557) 1 NC_007946.1 hypothetical protein 5557 3993031 UTI89_C0006 Escherichia coli UTI89 hypothetical protein YP_539047.1 5309 R 364106 CDS YP_539048.1 91209062 3993032 complement(5569..6345) 1 NC_007946.1 hypothetical protein 6345 yaaA 3993032 yaaA Escherichia coli UTI89 hypothetical protein YP_539048.1 5569 R 364106 CDS YP_539049.1 91209063 3993033 complement(6415..7845) 1 NC_007946.1 transporter YaaJ 7845 yaaJ 3993033 yaaJ Escherichia coli UTI89 transporter YaaJ YP_539049.1 6415 R 364106 CDS YP_539050.2 162138515 3993034 8124..9077 1 NC_007946.1 transaldolase B 9077 talB 3993034 talB Escherichia coli UTI89 transaldolase B YP_539050.2 8124 D 364106 CDS YP_539051.1 91209065 3993035 9189..9779 1 NC_007946.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9779 mogA 3993035 mogA Escherichia coli UTI89 molybdenum cofactor biosynthesis protein MogA YP_539051.1 9189 D 364106 CDS YP_539052.1 91209066 3993036 complement(9984..10550) 1 NC_007946.1 hypothetical protein 10550 yaaH 3993036 yaaH Escherichia coli UTI89 hypothetical protein YP_539052.1 9984 R 364106 CDS YP_539053.1 91209067 3993037 complement(10699..11412) 1 NC_007946.1 hypothetical protein 11412 yaaW 3993037 yaaW Escherichia coli UTI89 hypothetical protein YP_539053.1 10699 R 364106 CDS YP_539055.1 91209069 3993039 complement(11438..11842) 1 NC_007946.1 hypothetical protein 11842 yaaI 3993039 yaaI Escherichia coli UTI89 hypothetical protein YP_539055.1 11438 R 364106 CDS YP_539056.1 91209070 3993040 complement(12172..14208) 1 NC_007946.1 glutamate dehydrogenase 14208 3993040 UTI89_C0015 Escherichia coli UTI89 glutamate dehydrogenase YP_539056.1 12172 R 364106 CDS YP_539057.1 91209071 3993041 12214..14130 1 NC_007946.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14130 dnaK 3993041 dnaK Escherichia coli UTI89 molecular chaperone DnaK YP_539057.1 12214 D 364106 CDS YP_539058.1 91209072 3993042 14219..15349 1 NC_007946.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 15349 dnaJ 3993042 dnaJ Escherichia coli UTI89 molecular chaperone DnaJ YP_539058.1 14219 D 364106 CDS YP_539059.1 91209073 3993043 complement(15454..15663) 1 NC_007946.1 gef membrane toxin 15663 gef 3993043 gef Escherichia coli UTI89 gef membrane toxin YP_539059.1 15454 R 364106 CDS YP_539060.1 91209074 3992736 16218..16979 1 NC_007946.1 hypothetical protein 16979 3992736 UTI89_C0019 Escherichia coli UTI89 hypothetical protein YP_539060.1 16218 D 364106 CDS YP_539061.1 91209075 3992737 16963..18492 1 NC_007946.1 hypothetical protein 18492 3992737 UTI89_C0020 Escherichia coli UTI89 hypothetical protein YP_539061.1 16963 D 364106 CDS YP_539062.1 91209076 3992738 18621..19880 1 NC_007946.1 hypothetical protein 19880 3992738 UTI89_C0021 Escherichia coli UTI89 hypothetical protein YP_539062.1 18621 D 364106 CDS YP_539063.1 91209077 3992739 20115..21281 1 NC_007946.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 21281 nhaA 3992739 nhaA Escherichia coli UTI89 pH-dependent sodium/proton antiporter YP_539063.1 20115 D 364106 CDS YP_539064.2 162138514 3992740 21347..22246 1 NC_007946.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 22246 nhaR 3992740 nhaR Escherichia coli UTI89 transcriptional activator NhaR YP_539064.2 21347 D 364106 CDS YP_539065.1 91209079 3992741 22258..22590 1 NC_007946.1 hypothetical protein 22590 3992741 UTI89_C0024 Escherichia coli UTI89 hypothetical protein YP_539065.1 22258 D 364106 CDS YP_539066.1 91209080 3992742 complement(22342..22605) 1 NC_007946.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 22605 rpsT 3992742 rpsT Escherichia coli UTI89 30S ribosomal protein S20 YP_539066.1 22342 R 364106 CDS YP_539067.1 91209081 3992743 22708..22926 1 NC_007946.1 hypothetical protein 22926 yaaY 3992743 yaaY Escherichia coli UTI89 hypothetical protein YP_539067.1 22708 D 364106 CDS YP_539068.1 91209082 3992744 22934..23875 1 NC_007946.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 23875 ribF 3992744 ribF Escherichia coli UTI89 bifunctional riboflavin kinase/FMN adenylyltransferase YP_539068.1 22934 D 364106 CDS YP_539069.1 91209083 3992745 23918..26734 1 NC_007946.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 26734 ileS 3992745 ileS Escherichia coli UTI89 isoleucyl-tRNA synthetase YP_539069.1 23918 D 364106 CDS YP_539070.1 91209084 3992746 26734..27228 1 NC_007946.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 27228 lspA 3992746 lspA Escherichia coli UTI89 lipoprotein signal peptidase YP_539070.1 26734 D 364106 CDS YP_539071.1 91209085 3992747 27336..27785 1 NC_007946.1 peptidyl-prolyl cis- trans isomerase 27785 slpA 3992747 slpA Escherichia coli UTI89 peptidyl-prolyl cis- trans isomerase YP_539071.1 27336 D 364106 CDS YP_539072.1 91209086 3992748 27787..28737 1 NC_007946.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 28737 ispH 3992748 ispH Escherichia coli UTI89 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_539072.1 27787 D 364106 CDS YP_539073.1 91209087 3992749 28803..29717 1 NC_007946.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 29717 yaaF 3992749 yaaF Escherichia coli UTI89 ribonucleoside hydrolase RihC YP_539073.1 28803 D 364106 CDS YP_539074.1 91209088 3992750 29740..30105 1 NC_007946.1 hypothetical protein 30105 3992750 UTI89_C0033 Escherichia coli UTI89 hypothetical protein YP_539074.1 29740 D 364106 CDS YP_539075.1 91209089 3992751 30266..31087 1 NC_007946.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 31087 dapB 3992751 dapB Escherichia coli UTI89 dihydrodipicolinate reductase YP_539075.1 30266 D 364106 CDS YP_539076.1 91209090 3992752 complement(31099..31296) 1 NC_007946.1 hypothetical protein 31296 3992752 UTI89_C0035 Escherichia coli UTI89 hypothetical protein YP_539076.1 31099 R 364106 CDS YP_539077.1 91209091 3992753 31516..32691 1 NC_007946.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 32691 carA 3992753 carA Escherichia coli UTI89 carbamoyl phosphate synthase small subunit YP_539077.1 31516 D 364106 CDS YP_539078.1 91209092 3992754 32709..35930 1 NC_007946.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 35930 carB 3992754 carB Escherichia coli UTI89 carbamoyl phosphate synthase large subunit YP_539078.1 32709 D 364106 CDS YP_539079.1 91209093 3992755 36103..36612 1 NC_007946.1 transposase 36612 3992755 UTI89_C0038 Escherichia coli UTI89 transposase YP_539079.1 36103 D 364106 CDS YP_539080.1 91209094 3993409 complement(36649..36867) 1 NC_007946.1 hypothetical protein 36867 3993409 UTI89_C0039 Escherichia coli UTI89 hypothetical protein YP_539080.1 36649 R 364106 CDS YP_539081.2 162138513 3993410 36902..37297 1 NC_007946.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 37297 caiF 3993410 caiF Escherichia coli UTI89 DNA-binding transcriptional activator CaiF YP_539081.2 36902 D 364106 CDS YP_539082.1 91209096 3993411 complement(37416..38027) 1 NC_007946.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 38027 caiE 3993411 caiE Escherichia coli UTI89 carnitine operon protein CaiE YP_539082.1 37416 R 364106 CDS YP_539083.1 91209097 3993412 complement(38012..38905) 1 NC_007946.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 38905 caiD 3993412 caiD Escherichia coli UTI89 carnitinyl-CoA dehydratase YP_539083.1 38012 R 364106 CDS YP_539084.1 91209098 3993413 complement(38906..40474) 1 NC_007946.1 crotonobetaine/carnitine-CoA ligase 40474 caiC 3993413 caiC Escherichia coli UTI89 crotonobetaine/carnitine-CoA ligase YP_539084.1 38906 R 364106 CDS YP_539085.1 91209099 3993414 complement(40532..41749) 1 NC_007946.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 41749 caiB 3993414 caiB Escherichia coli UTI89 crotonobetainyl-CoA:carnitine CoA-transferase YP_539085.1 40532 R 364106 CDS YP_539086.1 91209100 3993415 complement(41877..43019) 1 NC_007946.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 43019 caiA 3993415 caiA Escherichia coli UTI89 crotonobetainyl-CoA dehydrogenase YP_539086.1 41877 R 364106 CDS YP_539087.1 91209101 3993416 complement(43050..44564) 1 NC_007946.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 44564 caiT 3993416 caiT Escherichia coli UTI89 L-carnitine/gamma-butyrobetaine antiporter YP_539087.1 43050 R 364106 CDS YP_539088.2 162138512 3993417 45037..45807 1 NC_007946.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45807 fixA 3993417 fixA Escherichia coli UTI89 electron transfer flavoprotein FixA YP_539088.2 45037 D 364106 CDS YP_539089.1 91209103 3993418 45822..46763 1 NC_007946.1 involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 46763 fixB 3993418 fixB Escherichia coli UTI89 electron transfer flavoprotein FixB YP_539089.1 45822 D 364106 CDS YP_539090.1 91209104 3993419 46814..48100 1 NC_007946.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 48100 fixC 3993419 fixC Escherichia coli UTI89 oxidoreductase FixC YP_539090.1 46814 D 364106 CDS YP_539091.1 91209105 3993420 48097..48384 1 NC_007946.1 ferredoxin 48384 fixX 3993420 fixX Escherichia coli UTI89 ferredoxin YP_539091.1 48097 D 364106 CDS YP_539092.1 91209106 3993421 48443..49774 1 NC_007946.1 metabolite transport protein YaaU 49774 yaaU 3993421 yaaU Escherichia coli UTI89 metabolite transport protein YaaU YP_539092.1 48443 D 364106 CDS YP_539093.1 91209107 3993422 49882..50412 1 NC_007946.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 50412 yabF 3993422 yabF Escherichia coli UTI89 glutathione-regulated potassium-efflux system ancillary protein KefF YP_539093.1 49882 D 364106 CDS YP_539094.1 91209108 3993423 50405..52267 1 NC_007946.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52267 kefC 3993423 kefC Escherichia coli UTI89 glutathione-regulated potassium-efflux system protein KefC YP_539094.1 50405 D 364106 CDS YP_539095.1 91209109 3993424 52324..52938 1 NC_007946.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52938 folA 3993424 folA Escherichia coli UTI89 dihydrofolate reductase YP_539095.1 52324 D 364106 CDS YP_539096.1 91209110 3993425 53024..53257 1 NC_007946.1 antitoxin of gyrase inhibiting toxin-antitoxin system 53257 3993425 UTI89_C0055 Escherichia coli UTI89 antitoxin of gyrase inhibiting toxin-antitoxin system YP_539096.1 53024 D 364106 CDS YP_539097.1 91209111 3993426 complement(53572..54420) 1 NC_007946.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 54420 apaH 3993426 apaH Escherichia coli UTI89 diadenosine tetraphosphatase YP_539097.1 53572 R 364106 CDS YP_539098.1 91209112 3993427 complement(54427..54804) 1 NC_007946.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 54804 apaG 3993427 apaG Escherichia coli UTI89 ApaG protein YP_539098.1 54427 R 364106 CDS YP_539099.1 91209113 3993619 complement(54807..55628) 1 NC_007946.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 55628 ksgA 3993619 ksgA Escherichia coli UTI89 dimethyladenosine transferase YP_539099.1 54807 R 364106 CDS YP_539100.1 91209114 3993620 complement(55625..56614) 1 NC_007946.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 56614 pdxA 3993620 pdxA Escherichia coli UTI89 4-hydroxythreonine-4-phosphate dehydrogenase YP_539100.1 55625 R 364106 CDS YP_539101.1 91209115 3993621 complement(56614..57900) 1 NC_007946.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 57900 surA 3993621 surA Escherichia coli UTI89 peptidyl-prolyl cis-trans isomerase SurA YP_539101.1 56614 R 364106 CDS YP_539102.1 91209116 3993622 complement(57953..60307) 1 NC_007946.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 60307 imp 3993622 imp Escherichia coli UTI89 organic solvent tolerance protein YP_539102.1 57953 R 364106 CDS YP_539103.2 162138511 3993623 60562..61377 1 NC_007946.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 61377 djlA 3993623 djlA Escherichia coli UTI89 Dna-J like membrane chaperone protein YP_539103.2 60562 D 364106 CDS YP_539104.1 91209118 3993624 complement(61527..62186) 1 NC_007946.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 62186 rluA 3993624 rluA Escherichia coli UTI89 23S rRNA/tRNA pseudouridine synthase A YP_539104.1 61527 R 364106 CDS YP_539105.1 91209119 3993625 complement(62198..65104) 1 NC_007946.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 65104 hepA 3993625 hepA Escherichia coli UTI89 ATP-dependent helicase HepA YP_539105.1 62198 R 364106 CDS YP_539106.1 91209120 3993626 complement(65268..67619) 1 NC_007946.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 67619 polB 3993626 polB Escherichia coli UTI89 DNA polymerase II YP_539106.1 65268 R 364106 CDS YP_539107.1 91209121 3993627 complement(67694..68389) 1 NC_007946.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 68389 araD 3993627 araD Escherichia coli UTI89 L-ribulose-5-phosphate 4-epimerase YP_539107.1 67694 R 364106 CDS YP_539108.1 91209122 3993628 complement(68674..70176) 1 NC_007946.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 70176 araA 3993628 araA Escherichia coli UTI89 L-arabinose isomerase YP_539108.1 68674 R 364106 CDS YP_539109.1 91209123 3993629 complement(70187..71887) 1 NC_007946.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 71887 araB 3993629 araB Escherichia coli UTI89 ribulokinase YP_539109.1 70187 R 364106 CDS YP_539110.1 91209124 3993630 72175..73071 1 NC_007946.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 73071 araC 3993630 araC Escherichia coli UTI89 DNA-binding transcriptional regulator AraC YP_539110.1 72175 D 364106 CDS YP_539111.1 91209125 3993631 73336..73458 1 NC_007946.1 hypothetical protein 73458 3993631 UTI89_C0070 Escherichia coli UTI89 hypothetical protein YP_539111.1 73336 D 364106 CDS YP_539112.1 91209126 3993632 73583..74194 1 NC_007946.1 hypothetical protein 74194 3993632 UTI89_C0071 Escherichia coli UTI89 hypothetical protein YP_539112.1 73583 D 364106 CDS YP_539113.1 91209127 3993633 74440..74862 1 NC_007946.1 hypothetical protein 74862 3993633 UTI89_C0072 Escherichia coli UTI89 hypothetical protein YP_539113.1 74440 D 364106 CDS YP_539114.1 91209128 3993634 75017..75781 1 NC_007946.1 hypothetical protein 75781 yabI 3993634 yabI Escherichia coli UTI89 hypothetical protein YP_539114.1 75017 D 364106 CDS YP_539115.1 91209129 3993635 complement(75895..76614) 1 NC_007946.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 76614 thiQ 3993635 thiQ Escherichia coli UTI89 thiamine transporter ATP-binding subunit YP_539115.1 75895 R 364106 CDS YP_539116.1 91209130 3993636 complement(76577..78187) 1 NC_007946.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 78187 thiP 3993636 thiP Escherichia coli UTI89 thiamine transporter membrane protein YP_539116.1 76577 R 364106 CDS YP_539117.2 162138510 3993637 complement(78163..79146) 1 NC_007946.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 79146 tbpA 3993637 tbpA Escherichia coli UTI89 thiamine transporter substrate binding subunit YP_539117.2 78163 R 364106 CDS YP_539118.1 91209132 3993638 complement(79310..80986) 1 NC_007946.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 80986 yabN 3993638 yabN Escherichia coli UTI89 transcriptional regulator SgrR YP_539118.1 79310 R 364106 CDS YP_539119.1 91209133 3994500 complement(81293..81898) 1 NC_007946.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 81898 leuD 3994500 leuD Escherichia coli UTI89 isopropylmalate isomerase small subunit YP_539119.1 81293 R 364106 CDS YP_539120.1 91209134 3994501 complement(81909..83309) 1 NC_007946.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 83309 leuC 3994501 leuC Escherichia coli UTI89 isopropylmalate isomerase large subunit YP_539120.1 81909 R 364106 CDS YP_539121.1 91209135 3994502 complement(83312..84406) 1 NC_007946.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 84406 leuB 3994502 leuB Escherichia coli UTI89 3-isopropylmalate dehydrogenase YP_539121.1 83312 R 364106 CDS YP_539122.1 91209136 3994503 complement(84403..85974) 1 NC_007946.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 85974 leuA 3994503 leuA Escherichia coli UTI89 2-isopropylmalate synthase YP_539122.1 84403 R 364106 CDS YP_539123.1 91209137 3994504 complement(86066..86152) 1 NC_007946.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 86152 leuL 3994504 leuL Escherichia coli UTI89 leu operon leader peptide YP_539123.1 86066 R 364106 CDS YP_539124.1 91209138 3994505 86611..86733 1 NC_007946.1 hypothetical protein 86733 3994505 UTI89_C0083 Escherichia coli UTI89 hypothetical protein YP_539124.1 86611 D 364106 CDS YP_539125.1 91209139 3994506 86810..87754 1 NC_007946.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 87754 leuO 3994506 leuO Escherichia coli UTI89 leucine transcriptional activator YP_539125.1 86810 D 364106 CDS YP_539126.2 162138509 3994507 88072..89796 1 NC_007946.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 89796 ilvI 3994507 ilvI Escherichia coli UTI89 acetolactate synthase 3 catalytic subunit YP_539126.2 88072 D 364106 CDS YP_539127.2 162138508 3994508 89799..90290 1 NC_007946.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 90290 ilvH 3994508 ilvH Escherichia coli UTI89 acetolactate synthase 3 regulatory subunit YP_539127.2 89799 D 364106 CDS YP_539128.1 91209142 3994509 90293..90388 1 NC_007946.1 FruR leader peptide 90388 fruL 3994509 fruL Escherichia coli UTI89 FruR leader peptide YP_539128.1 90293 D 364106 CDS YP_539129.1 91209143 3994510 90342..90473 1 NC_007946.1 hypothetical protein 90473 3994510 UTI89_C0088 Escherichia coli UTI89 hypothetical protein YP_539129.1 90342 D 364106 CDS YP_539130.1 91209144 3994511 90470..91474 1 NC_007946.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 91474 fruR 3994511 fruR Escherichia coli UTI89 DNA-binding transcriptional regulator FruR YP_539130.1 90470 D 364106 CDS YP_539131.1 91209145 3994512 92040..92534 1 NC_007946.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 92534 mraZ 3994512 mraZ Escherichia coli UTI89 cell division protein MraZ YP_539131.1 92040 D 364106 CDS YP_539132.1 91209146 3994513 92536..93477 1 NC_007946.1 yabC, orfB; S-adenosyl-methyltransferase 93477 mraW 3994513 mraW Escherichia coli UTI89 S-adenosyl-methyltransferase YP_539132.1 92536 D 364106 CDS YP_539133.1 91209147 3994514 93474..93839 1 NC_007946.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 93839 ftsL 3994514 ftsL Escherichia coli UTI89 cell division protein FtsL YP_539133.1 93474 D 364106 CDS YP_539134.1 91209148 3994515 93855..95621 1 NC_007946.1 peptidoglycan synthetase FtsI 95621 ftsI 3994515 ftsI Escherichia coli UTI89 peptidoglycan synthetase FtsI YP_539134.1 93855 D 364106 CDS YP_539135.1 91209149 3994516 95608..97095 1 NC_007946.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 97095 murE 3994516 murE Escherichia coli UTI89 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_539135.1 95608 D 364106 CDS YP_539136.1 91209150 3994517 97092..98450 1 NC_007946.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 98450 murF 3994517 murF Escherichia coli UTI89 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_539136.1 97092 D 364106 CDS YP_539137.1 91209151 3994518 98444..99526 1 NC_007946.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 99526 mraY 3994518 mraY Escherichia coli UTI89 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_539137.1 98444 D 364106 CDS YP_539138.1 91209152 3992618 99529..100845 1 NC_007946.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 100845 murD 3992618 murD Escherichia coli UTI89 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_539138.1 99529 D 364106 CDS YP_539139.1 91209153 3992619 100842..102089 1 NC_007946.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 102089 ftsW 3992619 ftsW Escherichia coli UTI89 cell division protein FtsW YP_539139.1 100842 D 364106 CDS YP_539140.1 91209154 3992620 102086..103153 1 NC_007946.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 103153 murG 3992620 murG Escherichia coli UTI89 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_539140.1 102086 D 364106 CDS YP_539141.1 91209155 3992621 103207..104682 1 NC_007946.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 104682 murC 3992621 murC Escherichia coli UTI89 UDP-N-acetylmuramate--L-alanine ligase YP_539141.1 103207 D 364106 CDS YP_539142.1 91209156 3992622 104675..105595 1 NC_007946.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 105595 ddl 3992622 ddl Escherichia coli UTI89 D-alanine--D-alanine ligase YP_539142.1 104675 D 364106 CDS YP_539143.1 91209157 3992623 105597..106427 1 NC_007946.1 involved in septum formation; cell division protein FtsQ 106427 ftsQ 3992623 ftsQ Escherichia coli UTI89 cell division protein FtsQ YP_539143.1 105597 D 364106 CDS YP_539144.1 91209158 3992624 106424..107686 1 NC_007946.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 107686 ftsA 3992624 ftsA Escherichia coli UTI89 cell division protein FtsA YP_539144.1 106424 D 364106 CDS YP_539145.1 91209159 3992625 107747..108898 1 NC_007946.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 108898 ftsZ 3992625 ftsZ Escherichia coli UTI89 cell division protein FtsZ YP_539145.1 107747 D 364106 CDS YP_539146.1 91209160 3992626 108999..109916 1 NC_007946.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 109916 lpxC 3992626 lpxC Escherichia coli UTI89 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_539146.1 108999 D 364106 CDS YP_539147.2 162138507 3992627 110147..110659 1 NC_007946.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 110659 secM 3992627 secM Escherichia coli UTI89 SecA regulator SecM YP_539147.2 110147 D 364106 CDS YP_539148.1 91209162 3992628 110721..113426 1 NC_007946.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 113426 secA 3992628 secA Escherichia coli UTI89 preprotein translocase subunit SecA YP_539148.1 110721 D 364106 CDS YP_539149.1 91209163 3992629 113486..113884 1 NC_007946.1 nucleoside triphosphate pyrophosphohydrolase 113884 mutT 3992629 mutT Escherichia coli UTI89 nucleoside triphosphate pyrophosphohydrolase YP_539149.1 113486 D 364106 CDS YP_539150.1 91209164 3992630 complement(113972..114169) 1 NC_007946.1 zinc-binding protein 114169 yacG 3992630 yacG Escherichia coli UTI89 zinc-binding protein YP_539150.1 113972 R 364106 CDS YP_539151.1 91209165 3992631 complement(114179..114922) 1 NC_007946.1 hypothetical protein 114922 yacF 3992631 yacF Escherichia coli UTI89 hypothetical protein YP_539151.1 114179 R 364106 CDS YP_539152.1 91209166 3992632 complement(114922..115542) 1 NC_007946.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 115542 coaE 3992632 coaE Escherichia coli UTI89 dephospho-CoA kinase YP_539152.1 114922 R 364106 CDS YP_539153.1 91209167 3992633 115767..116810 1 NC_007946.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 116810 guaC 3992633 guaC Escherichia coli UTI89 guanosine 5'-monophosphate oxidoreductase YP_539153.1 115767 D 364106 CDS YP_539154.1 91209168 3992634 complement(116845..118047) 1 NC_007946.1 type IV pilin biogenesis protein 118047 hofC 3992634 hofC Escherichia coli UTI89 type IV pilin biogenesis protein YP_539154.1 116845 R 364106 CDS YP_539155.1 91209169 3992635 complement(118037..119422) 1 NC_007946.1 hypothetical protein 119422 hofB 3992635 hofB Escherichia coli UTI89 hypothetical protein YP_539155.1 118037 R 364106 CDS YP_539156.1 91209170 3992636 complement(119432..119872) 1 NC_007946.1 major pilin subunit 119872 ppdD 3992636 ppdD Escherichia coli UTI89 major pilin subunit YP_539156.1 119432 R 364106 CDS YP_539157.1 91209171 3992637 119890..120063 1 NC_007946.1 hypothetical protein 120063 3992637 UTI89_C0116 Escherichia coli UTI89 hypothetical protein YP_539157.1 119890 D 364106 CDS YP_539158.2 162138506 3993332 complement(120076..120969) 1 NC_007946.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 120969 nadC 3993332 nadC Escherichia coli UTI89 quinolinate phosphoribosyltransferase YP_539158.2 120076 R 364106 CDS YP_539159.1 91209173 3993333 121057..121608 1 NC_007946.1 N-acetyl-anhydromuranmyl-L-alanine amidase 121608 ampD 3993333 ampD Escherichia coli UTI89 N-acetyl-anhydromuranmyl-L-alanine amidase YP_539159.1 121057 D 364106 CDS YP_539160.1 91209174 3993334 121605..122459 1 NC_007946.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 122459 ampE 3993334 ampE Escherichia coli UTI89 regulatory protein AmpE YP_539160.1 121605 D 364106 CDS YP_539161.1 91209175 3993335 complement(122502..123872) 1 NC_007946.1 aromatic amino acid transporter 123872 aroP 3993335 aroP Escherichia coli UTI89 aromatic amino acid transporter YP_539161.1 122502 R 364106 CDS YP_539162.1 91209176 3993336 124400..126181 1 NC_007946.1 uropathogenic specific protein 126181 usp 3993336 usp Escherichia coli UTI89 uropathogenic specific protein YP_539162.1 124400 D 364106 CDS YP_539163.1 91209177 3993337 126184..126468 1 NC_007946.1 hypothetical protein 126468 3993337 UTI89_C0122 Escherichia coli UTI89 hypothetical protein YP_539163.1 126184 D 364106 CDS YP_539164.1 91209178 3993338 126876..127166 1 NC_007946.1 hypothetical protein 127166 3993338 UTI89_C0123 Escherichia coli UTI89 hypothetical protein YP_539164.1 126876 D 364106 CDS YP_539165.1 91209179 3993339 127575..127865 1 NC_007946.1 hypothetical protein 127865 3993339 UTI89_C0124 Escherichia coli UTI89 hypothetical protein YP_539165.1 127575 D 364106 CDS YP_539166.2 162138505 3993340 128321..129085 1 NC_007946.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 129085 pdhR 3993340 pdhR Escherichia coli UTI89 transcriptional regulator PdhR YP_539166.2 128321 D 364106 CDS YP_539167.1 91209181 3993341 complement(129082..129264) 1 NC_007946.1 hypothetical protein 129264 3993341 UTI89_C0126 Escherichia coli UTI89 hypothetical protein YP_539167.1 129082 R 364106 CDS YP_539168.1 91209182 3993342 129246..131909 1 NC_007946.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 131909 aceE 3993342 aceE Escherichia coli UTI89 pyruvate dehydrogenase subunit E1 YP_539168.1 129246 D 364106 CDS YP_539169.1 91209183 3993343 131924..133816 1 NC_007946.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 133816 aceF 3993343 aceF Escherichia coli UTI89 dihydrolipoamide acetyltransferase YP_539169.1 131924 D 364106 CDS YP_539170.2 162138504 3993344 134024..135448 1 NC_007946.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 135448 lpdA 3993344 lpdA Escherichia coli UTI89 dihydrolipoamide dehydrogenase YP_539170.2 134024 D 364106 CDS YP_539171.1 91209185 3993345 complement(135690..137447) 1 NC_007946.1 hypothetical protein 137447 yacH 3993345 yacH Escherichia coli UTI89 hypothetical protein YP_539171.1 135690 R 364106 CDS YP_539172.2 162138503 3993346 137802..140399 1 NC_007946.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 140399 acnB 3993346 acnB Escherichia coli UTI89 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_539172.2 137802 D 364106 CDS YP_539173.2 162138502 3993347 140574..140936 1 NC_007946.1 hypothetical protein 140936 yacL 3993347 yacL Escherichia coli UTI89 hypothetical protein YP_539173.2 140574 D 364106 CDS YP_539174.1 91209188 3993348 complement(140974..141768) 1 NC_007946.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 141768 speD 3993348 speD Escherichia coli UTI89 S-adenosylmethionine decarboxylase YP_539174.1 140974 R 364106 CDS YP_539175.1 91209189 3993349 complement(141784..142650) 1 NC_007946.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 142650 speE 3993349 speE Escherichia coli UTI89 spermidine synthase YP_539175.1 141784 R 364106 CDS YP_539176.1 91209190 3993350 complement(142756..143274) 1 NC_007946.1 hypothetical protein 143274 yacC 3993350 yacC Escherichia coli UTI89 hypothetical protein YP_539176.1 142756 R 364106 CDS YP_539177.2 162138501 3992950 143269..144819 1 NC_007946.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 144819 cueO 3992950 cueO Escherichia coli UTI89 multicopper oxidase YP_539177.2 143269 D 364106 CDS YP_539178.1 91209192 3992951 complement(144866..147274) 1 NC_007946.1 glucose dehydrogenase 147274 gcd 3992951 gcd Escherichia coli UTI89 glucose dehydrogenase YP_539178.1 144866 R 364106 CDS YP_539179.1 91209193 3992952 147423..147998 1 NC_007946.1 hypoxanthine phosphoribosyltransferase 147998 hpt 3992952 hpt Escherichia coli UTI89 hypoxanthine phosphoribosyltransferase YP_539179.1 147423 D 364106 CDS YP_539180.1 91209194 3992953 complement(148039..148701) 1 NC_007946.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 148701 yadF 3992953 yadF Escherichia coli UTI89 carbonic anhydrase YP_539180.1 148039 R 364106 CDS YP_539181.1 91209195 3992954 148810..149736 1 NC_007946.1 hypothetical protein 149736 yadG 3992954 yadG Escherichia coli UTI89 hypothetical protein YP_539181.1 148810 D 364106 CDS YP_539182.1 91209196 3992955 149733..150503 1 NC_007946.1 ABC transporter 150503 yadH 3992955 yadH Escherichia coli UTI89 ABC transporter YP_539182.1 149733 D 364106 CDS YP_539183.1 91209197 3992956 150608..151048 1 NC_007946.1 PTS system IIA component YadI 151048 yadI 3992956 yadI Escherichia coli UTI89 PTS system IIA component YadI YP_539183.1 150608 D 364106 CDS YP_539184.1 91209198 3992957 151112..152341 1 NC_007946.1 hypothetical protein 152341 yadE 3992957 yadE Escherichia coli UTI89 hypothetical protein YP_539184.1 151112 D 364106 CDS YP_539185.1 91209199 3992958 complement(152345..152725) 1 NC_007946.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 152725 panD 3992958 panD Escherichia coli UTI89 aspartate alpha-decarboxylase YP_539185.1 152345 R 364106 CDS YP_539186.1 91209200 3992959 152693..152878 1 NC_007946.1 hypothetical protein 152878 3992959 UTI89_C0145 Escherichia coli UTI89 hypothetical protein YP_539186.1 152693 D 364106 CDS YP_539187.1 91209201 3992960 152999..153883 1 NC_007946.1 hypothetical protein 153883 yadD 3992960 yadD Escherichia coli UTI89 hypothetical protein YP_539187.1 152999 D 364106 CDS YP_539188.1 91209202 3992961 complement(153965..154816) 1 NC_007946.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 154816 panC 3992961 panC Escherichia coli UTI89 pantoate--beta-alanine ligase YP_539188.1 153965 R 364106 CDS YP_539189.1 91209203 3992962 complement(154828..155622) 1 NC_007946.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 155622 panB 3992962 panB Escherichia coli UTI89 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_539189.1 154828 R 364106 CDS YP_539190.1 91209204 3992963 complement(155734..157023) 1 NC_007946.1 fimbrial-like adhesin protein 157023 yadC 3992963 yadC Escherichia coli UTI89 fimbrial-like adhesin protein YP_539190.1 155734 R 364106 CDS YP_539191.1 91209205 3992964 complement(157049..157645) 1 NC_007946.1 fimbrial subunit YadK 157645 yadK 3992964 yadK Escherichia coli UTI89 fimbrial subunit YadK YP_539191.1 157049 R 364106 CDS YP_539192.1 91209206 3992965 complement(157672..158286) 1 NC_007946.1 fimbrial subunit YadL 158286 yadL 3992965 yadL Escherichia coli UTI89 fimbrial subunit YadL YP_539192.1 157672 R 364106 CDS YP_539193.1 91209207 3992966 complement(158292..158858) 1 NC_007946.1 fimbrial subunit YadM 158858 yadM 3992966 yadM Escherichia coli UTI89 fimbrial subunit YadM YP_539193.1 158292 R 364106 CDS YP_539194.1 91209208 3992967 complement(158875..161463) 1 NC_007946.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 161463 htrE 3992967 htrE Escherichia coli UTI89 outer membrane usher protein YP_539194.1 158875 R 364106 CDS YP_539195.1 91209209 3992968 complement(161498..162238) 1 NC_007946.1 chaperone protein EcpD 162238 ecpD 3992968 ecpD Escherichia coli UTI89 chaperone protein EcpD YP_539195.1 161498 R 364106 CDS YP_539196.1 91209210 3992969 complement(162347..162961) 1 NC_007946.1 fimbrial subunit YadN 162961 yadN 3992969 yadN Escherichia coli UTI89 fimbrial subunit YadN YP_539196.1 162347 R 364106 CDS YP_539197.1 91209211 3993233 complement(163299..163778) 1 NC_007946.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 163778 folK 3993233 folK Escherichia coli UTI89 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_539197.1 163299 R 364106 CDS YP_539198.1 91209212 3993234 complement(163775..165193) 1 NC_007946.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase 165193 pcnB 3993234 pcnB Escherichia coli UTI89 poly(A) polymerase YP_539198.1 163775 R 364106 CDS YP_539199.2 162138500 3993235 complement(165232..166128) 1 NC_007946.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 166128 yadB 3993235 yadB Escherichia coli UTI89 glutamyl-Q tRNA(Asp) synthetase YP_539199.2 165232 R 364106 CDS YP_539200.2 162138499 3993236 complement(166195..166650) 1 NC_007946.1 RNA polymerase-binding transcription factor 166650 dksA 3993236 dksA Escherichia coli UTI89 RNA polymerase-binding transcription factor YP_539200.2 166195 R 364106 CDS YP_539201.1 91209215 3993237 complement(166828..167532) 1 NC_007946.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 167532 sfsA 3993237 sfsA Escherichia coli UTI89 sugar fermentation stimulation protein A YP_539201.1 166828 R 364106 CDS YP_539202.1 91209216 3993238 complement(167547..168086) 1 NC_007946.1 2'-5' RNA ligase 168086 ligT 3993238 ligT Escherichia coli UTI89 2'-5' RNA ligase YP_539202.1 167547 R 364106 CDS YP_539203.1 91209217 3993239 168106..170580 1 NC_007946.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 170580 hrpB 3993239 hrpB Escherichia coli UTI89 ATP-dependent RNA helicase HrpB YP_539203.1 168106 D 364106 CDS YP_539204.1 91209218 3993240 complement(170508..170675) 1 NC_007946.1 hypothetical protein 170675 3993240 UTI89_C0163 Escherichia coli UTI89 hypothetical protein YP_539204.1 170508 R 364106 CDS YP_539205.1 91209219 3993241 170674..173208 1 NC_007946.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 173208 mrcB 3993241 mrcB Escherichia coli UTI89 penicillin-binding protein 1b YP_539205.1 170674 D 364106 CDS YP_539206.1 91209220 3993242 complement(173273..173455) 1 NC_007946.1 hypothetical protein 173455 3993242 UTI89_C0165 Escherichia coli UTI89 hypothetical protein YP_539206.1 173273 R 364106 CDS YP_539207.1 91209221 3993243 173428..175671 1 NC_007946.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 175671 fhuA 3993243 fhuA Escherichia coli UTI89 ferrichrome outer membrane transporter YP_539207.1 173428 D 364106 CDS YP_539208.2 162138498 3993244 175722..176519 1 NC_007946.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 176519 fhuC 3993244 fhuC Escherichia coli UTI89 iron-hydroxamate transporter ATP-binding subunit YP_539208.2 175722 D 364106 CDS YP_539209.1 91209223 3993245 176516..177409 1 NC_007946.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 177409 fhuD 3993245 fhuD Escherichia coli UTI89 iron-hydroxamate transporter substrate-binding subunit YP_539209.1 176516 D 364106 CDS YP_539210.1 91209224 3993246 177406..179388 1 NC_007946.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 179388 fhuB 3993246 fhuB Escherichia coli UTI89 iron-hydroxamate transporter permease subunit YP_539210.1 177406 D 364106 CDS YP_539211.1 91209225 3993247 complement(179423..180703) 1 NC_007946.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 180703 hemL 3993247 hemL Escherichia coli UTI89 glutamate-1-semialdehyde aminotransferase YP_539211.1 179423 R 364106 CDS YP_539212.1 91209226 3993248 180928..182349 1 NC_007946.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 182349 yadQ 3993248 yadQ Escherichia coli UTI89 chloride channel protein YP_539212.1 180928 D 364106 CDS YP_539213.1 91209227 3993249 182398..182775 1 NC_007946.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 182775 yadR 3993249 yadR Escherichia coli UTI89 iron-sulfur cluster insertion protein ErpA YP_539213.1 182398 D 364106 CDS YP_539214.1 91209228 3993250 complement(182822..183445) 1 NC_007946.1 hypothetical protein 183445 yadS 3993250 yadS Escherichia coli UTI89 hypothetical protein YP_539214.1 182822 R 364106 CDS YP_539215.1 91209229 3993251 complement(183483..184283) 1 NC_007946.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 184283 yadT 3993251 yadT Escherichia coli UTI89 vitamin B12-transporter protein BtuF YP_539215.1 183483 R 364106 CDS YP_539216.1 91209230 3992489 complement(184276..184974) 1 NC_007946.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 184974 mtn 3992489 mtn Escherichia coli UTI89 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_539216.1 184276 R 364106 CDS YP_539217.1 91209231 3992490 185058..186575 1 NC_007946.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 186575 dgt 3992490 dgt Escherichia coli UTI89 deoxyguanosinetriphosphate triphosphohydrolase YP_539217.1 185058 D 364106 CDS YP_539218.1 91209232 3992491 186705..188129 1 NC_007946.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 188129 degP 3992491 degP Escherichia coli UTI89 serine endoprotease YP_539218.1 186705 D 364106 CDS YP_539219.1 91209233 3992492 188307..189437 1 NC_007946.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 189437 cdaR 3992492 cdaR Escherichia coli UTI89 carbohydrate diacid transcriptional activator CdaR YP_539219.1 188307 D 364106 CDS YP_539220.1 91209234 3992493 complement(189491..189877) 1 NC_007946.1 hypothetical protein 189877 yaeH 3992493 yaeH Escherichia coli UTI89 hypothetical protein YP_539220.1 189491 R 364106 CDS YP_539221.1 91209235 3992494 complement(190189..191013) 1 NC_007946.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 191013 dapD 3992494 dapD Escherichia coli UTI89 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_539221.1 190189 R 364106 CDS YP_539222.1 91209236 3992495 complement(191044..193716) 1 NC_007946.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 193716 glnD 3992495 glnD Escherichia coli UTI89 PII uridylyl-transferase YP_539222.1 191044 R 364106 CDS YP_539223.1 91209237 3992496 complement(193778..194572) 1 NC_007946.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 194572 map 3992496 map Escherichia coli UTI89 methionine aminopeptidase YP_539223.1 193778 R 364106 CDS YP_539224.2 162138497 3992497 194940..195665 1 NC_007946.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 195665 rpsB 3992497 rpsB Escherichia coli UTI89 30S ribosomal protein S2 YP_539224.2 194940 D 364106 CDS YP_539225.1 91209239 3992498 complement(195617..196546) 1 NC_007946.1 hypothetical protein 196546 3992498 UTI89_C0184 Escherichia coli UTI89 hypothetical protein YP_539225.1 195617 R 364106 CDS YP_539226.1 91209240 3992499 195800..196651 1 NC_007946.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 196651 tsf 3992499 tsf Escherichia coli UTI89 elongation factor Ts YP_539226.1 195800 D 364106 CDS YP_539227.1 91209241 3992500 196798..197523 1 NC_007946.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 197523 pyrH 3992500 pyrH Escherichia coli UTI89 uridylate kinase YP_539227.1 196798 D 364106 CDS YP_539228.1 91209242 3992501 197673..198230 1 NC_007946.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 198230 frr 3992501 frr Escherichia coli UTI89 ribosome recycling factor YP_539228.1 197673 D 364106 CDS YP_539229.1 91209243 3992502 198322..199518 1 NC_007946.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 199518 dxr 3992502 dxr Escherichia coli UTI89 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_539229.1 198322 D 364106 CDS YP_539230.1 91209244 3992503 199704..200465 1 NC_007946.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 200465 uppS 3992503 uppS Escherichia coli UTI89 undecaprenyl pyrophosphate synthase YP_539230.1 199704 D 364106 CDS YP_539231.1 91209245 3992504 200478..201335 1 NC_007946.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 201335 cdsA 3992504 cdsA Escherichia coli UTI89 CDP-diglyceride synthase YP_539231.1 200478 D 364106 CDS YP_539232.1 91209246 3992505 201302..202699 1 NC_007946.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 202699 ecfE 3992505 ecfE Escherichia coli UTI89 zinc metallopeptidase RseP YP_539232.1 201302 D 364106 CDS YP_539233.1 91209247 3992506 202729..205161 1 NC_007946.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 205161 ecfK 3992506 ecfK Escherichia coli UTI89 outer membrane protein assembly factor YaeT YP_539233.1 202729 D 364106 CDS YP_539234.1 91209248 3992507 205283..205768 1 NC_007946.1 periplasmic chaperone 205768 hlpA 3992507 hlpA Escherichia coli UTI89 periplasmic chaperone YP_539234.1 205283 D 364106 CDS YP_539235.1 91209249 3992508 205772..206797 1 NC_007946.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 206797 lpxD 3992508 lpxD Escherichia coli UTI89 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_539235.1 205772 D 364106 CDS YP_539236.1 91209250 3994667 206809..207357 1 NC_007946.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 207357 fabZ 3994667 fabZ Escherichia coli UTI89 (3R)-hydroxymyristoyl-ACP dehydratase YP_539236.1 206809 D 364106 CDS YP_539237.1 91209251 3994668 207361..208149 1 NC_007946.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 208149 lpxA 3994668 lpxA Escherichia coli UTI89 UDP-N-acetylglucosamine acyltransferase YP_539237.1 207361 D 364106 CDS YP_539238.1 91209252 3994669 208149..209297 1 NC_007946.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 209297 lpxB 3994669 lpxB Escherichia coli UTI89 lipid-A-disaccharide synthase YP_539238.1 208149 D 364106 CDS YP_539239.1 91209253 3994670 209294..209890 1 NC_007946.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 209890 rnhB 3994670 rnhB Escherichia coli UTI89 ribonuclease HII YP_539239.1 209294 D 364106 CDS YP_539240.1 91209254 3994671 209927..213409 1 NC_007946.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 213409 dnaE 3994671 dnaE Escherichia coli UTI89 DNA polymerase III subunit alpha YP_539240.1 209927 D 364106 CDS YP_539241.1 91209255 3994672 213422..214381 1 NC_007946.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 214381 accA 3994672 accA Escherichia coli UTI89 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_539241.1 213422 D 364106 CDS YP_539242.1 91209256 3994673 214479..216620 1 NC_007946.1 lysine decarboxylase, constitutive 216620 ldcC 3994673 ldcC Escherichia coli UTI89 lysine decarboxylase, constitutive YP_539242.1 214479 D 364106 CDS YP_539243.2 162138496 3994674 216677..217066 1 NC_007946.1 hypothetical protein 217066 yaeR 3994674 yaeR Escherichia coli UTI89 hypothetical protein YP_539243.2 216677 D 364106 CDS YP_539244.1 91209258 3994675 217131..218429 1 NC_007946.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 218429 tilS 3994675 tilS Escherichia coli UTI89 tRNA(Ile)-lysidine synthetase YP_539244.1 217131 D 364106 CDS YP_539245.1 91209259 3994676 complement(218477..218737) 1 NC_007946.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 218737 rof 3994676 rof Escherichia coli UTI89 Rho-binding antiterminator YP_539245.1 218477 R 364106 CDS YP_539246.1 91209260 3994677 complement(218724..218942) 1 NC_007946.1 hypothetical protein 218942 yaeP 3994677 yaeP Escherichia coli UTI89 hypothetical protein YP_539246.1 218724 R 364106 CDS YP_539247.1 91209261 3994678 219090..219635 1 NC_007946.1 hypothetical protein 219635 yaeQ 3994678 yaeQ Escherichia coli UTI89 hypothetical protein YP_539247.1 219090 D 364106 CDS YP_539248.1 91209262 3994679 219632..220054 1 NC_007946.1 peptidyl-tRNA hydrolase domain-containing protein 220054 yaeJ 3994679 yaeJ Escherichia coli UTI89 peptidyl-tRNA hydrolase domain-containing protein YP_539248.1 219632 D 364106 CDS YP_539249.1 91209263 3994680 220068..220778 1 NC_007946.1 lipoprotein involved with copper homeostasis and adhesion 220778 cutF 3994680 cutF Escherichia coli UTI89 lipoprotein involved with copper homeostasis and adhesion YP_539249.1 220068 D 364106 CDS YP_539250.2 162138495 3994681 complement(220934..221758) 1 NC_007946.1 hypothetical protein 221758 yaeF 3994681 yaeF Escherichia coli UTI89 hypothetical protein YP_539250.2 220934 R 364106 CDS YP_539251.2 162138494 3994682 complement(221811..223529) 1 NC_007946.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 223529 proS 3994682 proS Escherichia coli UTI89 prolyl-tRNA synthetase YP_539251.2 221811 R 364106 CDS YP_539252.1 91209266 3994683 complement(223640..224347) 1 NC_007946.1 hypothetical protein 224347 yaeB 3994683 yaeB Escherichia coli UTI89 hypothetical protein YP_539252.1 223640 R 364106 CDS YP_539253.1 91209267 3994684 complement(224344..224748) 1 NC_007946.1 outer membrane lipoprotein 224748 rcsF 3994684 rcsF Escherichia coli UTI89 outer membrane lipoprotein YP_539253.1 224344 R 364106 CDS YP_539254.1 91209268 3994685 complement(224866..225681) 1 NC_007946.1 DL-methionine transporter substrate-binding subunit 225681 metQ 3994685 metQ Escherichia coli UTI89 DL-methionine transporter substrate-binding subunit YP_539254.1 224866 R 364106 CDS YP_539255.1 91209269 3994574 complement(225721..226374) 1 NC_007946.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit 226374 metI 3994574 metI Escherichia coli UTI89 DL-methionine transporter permease subunit YP_539255.1 225721 R 364106 CDS YP_539256.1 91209270 3994575 complement(226367..227398) 1 NC_007946.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 227398 metN 3994575 metN Escherichia coli UTI89 DL-methionine transporter ATP-binding subunit YP_539256.1 226367 R 364106 CDS YP_539257.1 91209271 3994576 227586..228158 1 NC_007946.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 228158 yaeD 3994576 yaeD Escherichia coli UTI89 D,D-heptose 1,7-bisphosphate phosphatase YP_539257.1 227586 D 364106 CDS YP_539261.1 91209275 3994586 233915..234718 1 NC_007946.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 234718 dkgB 3994586 dkgB Escherichia coli UTI89 2,5-diketo-D-gluconate reductase B YP_539261.1 233915 D 364106 CDS YP_539262.1 91209276 3994587 complement(234715..235629) 1 NC_007946.1 LysR family transcriptional regulator 235629 3994587 UTI89_C0227 Escherichia coli UTI89 LysR family transcriptional regulator YP_539262.1 234715 R 364106 CDS YP_539263.1 91209277 3992085 235846..236670 1 NC_007946.1 hypothetical protein 236670 yafD 3992085 yafD Escherichia coli UTI89 hypothetical protein YP_539263.1 235846 D 364106 CDS YP_539264.1 91209278 3992086 236748..237518 1 NC_007946.1 hypothetical protein 237518 yafE 3992086 yafE Escherichia coli UTI89 hypothetical protein YP_539264.1 236748 D 364106 CDS YP_539265.1 91209279 3992087 complement(237565..238923) 1 NC_007946.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 238923 mltD 3992087 mltD Escherichia coli UTI89 membrane-bound lytic murein transglycosylase D YP_539265.1 237565 R 364106 CDS YP_539266.1 91209280 3992088 complement(238995..239750) 1 NC_007946.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 239750 gloB 3992088 gloB Escherichia coli UTI89 hydroxyacylglutathione hydrolase YP_539266.1 238995 R 364106 CDS YP_539267.1 91209281 3992089 239766..240506 1 NC_007946.1 hypothetical protein 240506 yafS 3992089 yafS Escherichia coli UTI89 hypothetical protein YP_539267.1 239766 D 364106 CDS YP_539268.1 91209282 3992090 complement(240503..241081) 1 NC_007946.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 241081 rnhA 3992090 rnhA Escherichia coli UTI89 ribonuclease H YP_539268.1 240503 R 364106 CDS YP_539269.1 91209283 3992091 241026..241766 1 NC_007946.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 241766 dnaQ 3992091 dnaQ Escherichia coli UTI89 DNA polymerase III subunit epsilon YP_539269.1 241026 D 364106 CDS YP_539270.1 91209284 3992093 242304..243089 1 NC_007946.1 aminopeptidase 243089 yafT 3992093 yafT Escherichia coli UTI89 aminopeptidase YP_539270.1 242304 D 364106 CDS YP_539271.1 91209285 3992094 complement(243429..243908) 1 NC_007946.1 hypothetical protein 243908 3992094 UTI89_C0237 Escherichia coli UTI89 hypothetical protein YP_539271.1 243429 R 364106 CDS YP_539272.1 91209286 3992095 complement(243926..245368) 1 NC_007946.1 hypothetical protein 245368 3992095 UTI89_C0238 Escherichia coli UTI89 hypothetical protein YP_539272.1 243926 R 364106 CDS YP_539273.1 91209287 3992096 complement(245295..248762) 1 NC_007946.1 hypothetical protein 248762 3992096 UTI89_C0239 Escherichia coli UTI89 hypothetical protein YP_539273.1 245295 R 364106 CDS YP_539274.1 91209288 3992097 complement(248842..250284) 1 NC_007946.1 hypothetical protein 250284 3992097 UTI89_C0240 Escherichia coli UTI89 hypothetical protein YP_539274.1 248842 R 364106 CDS YP_539275.1 91209289 3992098 complement(250289..251032) 1 NC_007946.1 hypothetical protein 251032 3992098 UTI89_C0241 Escherichia coli UTI89 hypothetical protein YP_539275.1 250289 R 364106 CDS YP_539276.1 91209290 3992099 complement(251029..253788) 1 NC_007946.1 hypothetical protein 253788 3992099 UTI89_C0242 Escherichia coli UTI89 hypothetical protein YP_539276.1 251029 R 364106 CDS YP_539277.1 91209291 3992100 complement(253798..254562) 1 NC_007946.1 hypothetical protein 254562 3992100 UTI89_C0243 Escherichia coli UTI89 hypothetical protein YP_539277.1 253798 R 364106 CDS YP_539278.1 91209292 3992101 complement(254567..255913) 1 NC_007946.1 hypothetical protein 255913 3992101 UTI89_C0244 Escherichia coli UTI89 hypothetical protein YP_539278.1 254567 R 364106 CDS YP_539279.1 91209293 3992102 complement(255916..256440) 1 NC_007946.1 hypothetical protein 256440 3992102 UTI89_C0245 Escherichia coli UTI89 hypothetical protein YP_539279.1 255916 R 364106 CDS YP_539280.1 91209294 3993985 complement(256437..257729) 1 NC_007946.1 hypothetical protein 257729 3993985 UTI89_C0246 Escherichia coli UTI89 hypothetical protein YP_539280.1 256437 R 364106 CDS YP_539281.1 91209295 3993986 complement(257734..258783) 1 NC_007946.1 hypothetical protein 258783 3993986 UTI89_C0247 Escherichia coli UTI89 hypothetical protein YP_539281.1 257734 R 364106 CDS YP_539282.1 91209296 3993987 complement(258747..260588) 1 NC_007946.1 hypothetical protein 260588 3993987 UTI89_C0248 Escherichia coli UTI89 hypothetical protein YP_539282.1 258747 R 364106 CDS YP_539283.1 91209297 3993988 complement(260594..261019) 1 NC_007946.1 hypothetical protein 261019 3993988 UTI89_C0249 Escherichia coli UTI89 hypothetical protein YP_539283.1 260594 R 364106 CDS YP_539284.1 91209298 3993989 complement(261024..262508) 1 NC_007946.1 hypothetical protein 262508 3993989 UTI89_C0250 Escherichia coli UTI89 hypothetical protein YP_539284.1 261024 R 364106 CDS YP_539285.1 91209299 3993990 complement(262531..263034) 1 NC_007946.1 hypothetical protein 263034 3993990 UTI89_C0251 Escherichia coli UTI89 hypothetical protein YP_539285.1 262531 R 364106 CDS YP_539286.1 91209300 3993991 263740..264258 1 NC_007946.1 hypothetical protein 264258 3993991 UTI89_C0252 Escherichia coli UTI89 hypothetical protein YP_539286.1 263740 D 364106 CDS YP_539287.1 91209301 3993992 264479..266461 1 NC_007946.1 hypothetical protein 266461 3993992 UTI89_C0253 Escherichia coli UTI89 hypothetical protein YP_539287.1 264479 D 364106 CDS YP_539288.1 91209302 3993993 266568..267614 1 NC_007946.1 hypothetical protein 267614 3993993 UTI89_C0254 Escherichia coli UTI89 hypothetical protein YP_539288.1 266568 D 364106 CDS YP_539289.1 91209303 3993994 267607..269046 1 NC_007946.1 hypothetical protein 269046 3993994 UTI89_C0255 Escherichia coli UTI89 hypothetical protein YP_539289.1 267607 D 364106 CDS YP_539290.1 91209304 3993995 269021..269311 1 NC_007946.1 hypothetical protein 269311 3993995 UTI89_C0256 Escherichia coli UTI89 hypothetical protein YP_539290.1 269021 D 364106 CDS YP_539291.1 91209305 3993996 270562..271065 1 NC_007946.1 hypothetical protein 271065 3993996 UTI89_C0257 Escherichia coli UTI89 hypothetical protein YP_539291.1 270562 D 364106 CDS YP_539292.1 91209306 3993997 271135..271647 1 NC_007946.1 hypothetical protein 271647 3993997 UTI89_C0258 Escherichia coli UTI89 hypothetical protein YP_539292.1 271135 D 364106 CDS YP_539293.1 91209307 3993998 complement(271918..272697) 1 NC_007946.1 hypothetical protein 272697 3993998 UTI89_C0259 Escherichia coli UTI89 hypothetical protein YP_539293.1 271918 R 364106 CDS YP_539294.1 91209308 3993999 272842..273315 1 NC_007946.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 273315 ykfE 3993999 ykfE Escherichia coli UTI89 C-lysozyme inhibitor YP_539294.1 272842 D 364106 CDS YP_539295.2 162138493 3994000 complement(273358..275802) 1 NC_007946.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 275802 fadE 3994000 fadE Escherichia coli UTI89 acyl-CoA dehydrogenase YP_539295.2 273358 R 364106 CDS YP_539296.2 162138492 3994001 276042..276620 1 NC_007946.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 276620 gmhA 3994001 gmhA Escherichia coli UTI89 phosphoheptose isomerase YP_539296.2 276042 D 364106 CDS YP_539297.1 91209311 3994002 276810..277592 1 NC_007946.1 amidotransferase 277592 yafJ 3994002 yafJ Escherichia coli UTI89 amidotransferase YP_539297.1 276810 D 364106 CDS YP_539298.1 91209312 3994003 complement(277563..278303) 1 NC_007946.1 hypothetical protein 278303 yafK 3994003 yafK Escherichia coli UTI89 hypothetical protein YP_539298.1 277563 R 364106 CDS YP_539299.1 91209313 3994004 complement(278560..278697) 1 NC_007946.1 hypothetical protein 278697 3994004 UTI89_C0265 Escherichia coli UTI89 hypothetical protein YP_539299.1 278560 R 364106 CDS YP_539300.1 91209314 3990094 278672..279364 1 NC_007946.1 lipoprotein YafL 279364 yafL 3990094 yafL Escherichia coli UTI89 lipoprotein YafL YP_539300.1 278672 D 364106 CDS YP_539301.1 91209315 3990095 279540..280037 1 NC_007946.1 hypothetical protein 280037 yafM 3990095 yafM Escherichia coli UTI89 hypothetical protein YP_539301.1 279540 D 364106 CDS YP_539302.1 91209316 3990096 complement(280120..280329) 1 NC_007946.1 hypothetical protein 280329 3990096 UTI89_C0268 Escherichia coli UTI89 hypothetical protein YP_539302.1 280120 R 364106 CDS YP_539303.1 91209317 3990097 complement(280357..282096) 1 NC_007946.1 FhiA protein 282096 fhiA 3990097 fhiA Escherichia coli UTI89 FhiA protein YP_539303.1 280357 R 364106 CDS YP_539304.1 91209318 3990098 282038..282826 1 NC_007946.1 hypothetical protein 282826 mbhA 3990098 mbhA Escherichia coli UTI89 hypothetical protein YP_539304.1 282038 D 364106 CDS YP_539305.1 91209319 3990099 282897..283952 1 NC_007946.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 283952 dinP 3990099 dinP Escherichia coli UTI89 DNA polymerase IV YP_539305.1 282897 D 364106 CDS YP_539306.1 91209320 3990100 284004..284297 1 NC_007946.1 antitoxin of the YafO-YafN toxin-antitoxin system 284297 yafN 3990100 yafN Escherichia coli UTI89 antitoxin of the YafO-YafN toxin-antitoxin system YP_539306.1 284004 D 364106 CDS YP_539307.1 91209321 3990101 284300..284698 1 NC_007946.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 284698 yafO 3990101 yafO Escherichia coli UTI89 toxin YafO YP_539307.1 284300 D 364106 CDS YP_539308.1 91209322 3990102 284708..285160 1 NC_007946.1 hypothetical protein 285160 yafP 3990102 yafP Escherichia coli UTI89 hypothetical protein YP_539308.1 284708 D 364106 CDS YP_539309.1 91209323 3990103 285338..286489 1 NC_007946.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 286489 3990103 UTI89_C0275 Escherichia coli UTI89 hypothetical protein YP_539309.1 285338 D 364106 CDS YP_539310.2 162138491 3990104 286600..287100 1 NC_007946.1 similar to release factor 1 and 2; peptide chain release factor-like protein 287100 prfH 3990104 prfH Escherichia coli UTI89 peptide chain release factor-like protein YP_539310.2 286600 D 364106 CDS YP_539311.1 91209325 3990105 complement(287157..288614) 1 NC_007946.1 aminoacyl-histidine dipeptidase 288614 pepD 3990105 pepD Escherichia coli UTI89 aminoacyl-histidine dipeptidase YP_539311.1 287157 R 364106 CDS YP_539312.1 91209326 3990106 288875..289333 1 NC_007946.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 289333 gpt 3990106 gpt Escherichia coli UTI89 xanthine-guanine phosphoribosyltransferase YP_539312.1 288875 D 364106 CDS YP_539313.1 91209327 3990107 complement(289007..289459) 1 NC_007946.1 hypothetical protein 289459 3990107 UTI89_C0279 Escherichia coli UTI89 hypothetical protein YP_539313.1 289007 R 364106 CDS YP_539314.1 91209328 3990108 289425..290669 1 NC_007946.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 290669 frsA 3990108 frsA Escherichia coli UTI89 fermentation/respiration switch protein YP_539314.1 289425 D 364106 CDS YP_539315.1 91209329 3990109 290727..291128 1 NC_007946.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 291128 crl 3990109 crl Escherichia coli UTI89 DNA-binding transcriptional regulator Crl YP_539315.1 290727 D 364106 CDS YP_539316.1 91209330 3990110 complement(291238..292299) 1 NC_007946.1 outer membrane phosphoporin protein E 292299 phoE 3990110 phoE Escherichia coli UTI89 outer membrane phosphoporin protein E YP_539316.1 291238 R 364106 CDS YP_539317.2 162138490 3990111 292582..293685 1 NC_007946.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 293685 proB 3990111 proB Escherichia coli UTI89 gamma-glutamyl kinase YP_539317.2 292582 D 364106 CDS YP_539318.1 91209332 3990112 293697..294950 1 NC_007946.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 294950 proA 3990112 proA Escherichia coli UTI89 gamma-glutamyl phosphate reductase YP_539318.1 293697 D 364106 CDS YP_539319.1 91209333 3993776 295228..297168 1 NC_007946.1 integrase 297168 3993776 UTI89_C0286 Escherichia coli UTI89 integrase YP_539319.1 295228 D 364106 CDS YP_539320.1 91209334 3993777 complement(297292..297624) 1 NC_007946.1 hypothetical protein 297624 3993777 UTI89_C0287 Escherichia coli UTI89 hypothetical protein YP_539320.1 297292 R 364106 CDS YP_539321.1 91209335 3993778 complement(297787..299625) 1 NC_007946.1 similar to pathogenesis-related protein; hypothetical protein 299625 3993778 UTI89_C0288 Escherichia coli UTI89 hypothetical protein YP_539321.1 297787 R 364106 CDS YP_539322.1 91209336 3993779 complement(299622..301769) 1 NC_007946.1 hypothetical protein 301769 3993779 UTI89_C0289 Escherichia coli UTI89 hypothetical protein YP_539322.1 299622 R 364106 CDS YP_539323.1 91209337 3993780 302117..302680 1 NC_007946.1 resolvase 302680 3993780 UTI89_C0290 Escherichia coli UTI89 resolvase YP_539323.1 302117 D 364106 CDS YP_539324.1 91209338 3993781 complement(302838..303335) 1 NC_007946.1 hypothetical protein 303335 3993781 UTI89_C0291 Escherichia coli UTI89 hypothetical protein YP_539324.1 302838 R 364106 CDS YP_539325.1 91209339 3993782 303574..304038 1 NC_007946.1 transcription regulator 304038 3993782 UTI89_C0292 Escherichia coli UTI89 transcription regulator YP_539325.1 303574 D 364106 CDS YP_539326.1 91209340 3993783 complement(304545..305459) 1 NC_007946.1 hypothetical protein 305459 3993783 UTI89_C0293 Escherichia coli UTI89 hypothetical protein YP_539326.1 304545 R 364106 CDS YP_539327.1 91209341 3993785 305929..306267 1 NC_007946.1 CP4-like integrase 306267 3993785 UTI89_C0295 Escherichia coli UTI89 CP4-like integrase YP_539327.1 305929 D 364106 CDS YP_539328.1 91209342 3993786 complement(305979..306371) 1 NC_007946.1 hypothetical protein 306371 3993786 UTI89_C0296 Escherichia coli UTI89 hypothetical protein YP_539328.1 305979 R 364106 CDS YP_539329.1 91209343 3993787 complement(306702..307226) 1 NC_007946.1 hypothetical protein 307226 3993787 UTI89_C0297 Escherichia coli UTI89 hypothetical protein YP_539329.1 306702 R 364106 CDS YP_539330.1 91209344 3993788 311796..311993 1 NC_007946.1 hypothetical protein 311993 3993788 UTI89_C0298 Escherichia coli UTI89 hypothetical protein YP_539330.1 311796 D 364106 CDS YP_539331.1 91209345 3993789 312076..312291 1 NC_007946.1 InsA protein 312291 insA 3993789 insA Escherichia coli UTI89 InsA protein YP_539331.1 312076 D 364106 CDS YP_539332.1 91209346 3993790 complement(312482..312757) 1 NC_007946.1 hypothetical protein 312757 insB 3993790 insB Escherichia coli UTI89 hypothetical protein YP_539332.1 312482 R 364106 CDS YP_539333.1 91209347 3993791 312593..312769 1 NC_007946.1 InsB protein 312769 3993791 UTI89_C0301 Escherichia coli UTI89 InsB protein YP_539333.1 312593 D 364106 CDS YP_539334.1 91209348 3993792 313148..313378 1 NC_007946.1 hypothetical protein 313378 3993792 UTI89_C0302 Escherichia coli UTI89 hypothetical protein YP_539334.1 313148 D 364106 CDS YP_539335.1 91209349 3994040 313593..314207 1 NC_007946.1 hypothetical protein 314207 yagU 3994040 yagU Escherichia coli UTI89 hypothetical protein YP_539335.1 313593 D 364106 CDS YP_539336.1 91209350 3994041 complement(314456..314785) 1 NC_007946.1 ferredoxin 314785 ykgJ 3994041 ykgJ Escherichia coli UTI89 ferredoxin YP_539336.1 314456 R 364106 CDS YP_539337.1 91209351 3994042 complement(315092..315847) 1 NC_007946.1 hypothetical protein 315847 yagV 3994042 yagV Escherichia coli UTI89 hypothetical protein YP_539337.1 315092 R 364106 CDS YP_539338.1 91209352 3994043 complement(315771..317414) 1 NC_007946.1 hypothetical protein 317414 yagW 3994043 yagW Escherichia coli UTI89 hypothetical protein YP_539338.1 315771 R 364106 CDS YP_539339.1 91209353 3994044 complement(317404..319929) 1 NC_007946.1 hypothetical protein 319929 yagX 3994044 yagX Escherichia coli UTI89 hypothetical protein YP_539339.1 317404 R 364106 CDS YP_539340.1 91209354 3994045 complement(319955..320671) 1 NC_007946.1 hypothetical protein 320671 yagY 3994045 yagY Escherichia coli UTI89 hypothetical protein YP_539340.1 319955 R 364106 CDS YP_539341.1 91209355 3994046 complement(320680..321297) 1 NC_007946.1 MatB 321297 matB 3994046 matB Escherichia coli UTI89 MatB YP_539341.1 320680 R 364106 CDS YP_539342.1 91209356 3994047 complement(321340..321930) 1 NC_007946.1 hypothetical protein 321930 matA 3994047 matA Escherichia coli UTI89 hypothetical protein YP_539342.1 321340 R 364106 CDS YP_539343.1 91209357 3994048 complement(322335..322559) 1 NC_007946.1 hypothetical protein 322559 3994048 UTI89_C0311 Escherichia coli UTI89 hypothetical protein YP_539343.1 322335 R 364106 CDS YP_539344.1 91209358 3994049 322354..322644 1 NC_007946.1 hypothetical protein 322644 3994049 UTI89_C0312 Escherichia coli UTI89 hypothetical protein YP_539344.1 322354 D 364106 CDS YP_539345.1 91209359 3994050 complement(322966..323109) 1 NC_007946.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 323109 rpmJ 3994050 rpmJ Escherichia coli UTI89 50S ribosomal protein L36 YP_539345.1 322966 R 364106 CDS YP_539346.2 162138489 3994051 complement(323106..323369) 1 NC_007946.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 323369 rpmE2 3994051 rpmE2 Escherichia coli UTI89 50S ribosomal protein L31 YP_539346.2 323106 R 364106 CDS YP_539347.1 91209361 3994052 complement(324309..325451) 1 NC_007946.1 NADH-dependent flavin oxidoreductase 325451 3994052 UTI89_C0315 Escherichia coli UTI89 NADH-dependent flavin oxidoreductase YP_539347.1 324309 R 364106 CDS YP_539348.1 91209362 3994053 complement(325623..326543) 1 NC_007946.1 hypothetical protein 326543 ycjY 3994053 ycjY Escherichia coli UTI89 hypothetical protein YP_539348.1 325623 R 364106 CDS YP_539349.1 91209363 3994054 326637..327626 1 NC_007946.1 LysR family transcriptional regulator 327626 3994054 UTI89_C0317 Escherichia coli UTI89 LysR family transcriptional regulator YP_539349.1 326637 D 364106 CDS YP_539350.1 91209364 3994055 327751..328719 1 NC_007946.1 transcriptional regulator YcjZ 328719 ycjZ 3994055 ycjZ Escherichia coli UTI89 transcriptional regulator YcjZ YP_539350.1 327751 D 364106 CDS YP_539351.1 91209365 3994056 complement(328750..329739) 1 NC_007946.1 aldo/keto reductase 329739 3994056 UTI89_C0319 Escherichia coli UTI89 aldo/keto reductase YP_539351.1 328750 R 364106 CDS YP_539352.1 91209366 3994057 complement(329766..330617) 1 NC_007946.1 2,5-diketo-D-gluconate reductase A 330617 3994057 UTI89_C0320 Escherichia coli UTI89 2,5-diketo-D-gluconate reductase A YP_539352.1 329766 R 364106 CDS YP_539353.1 91209367 3994058 331183..335433 1 NC_007946.1 attaching and effacing protein, pathogenesis factor 335433 eaeH 3994058 eaeH Escherichia coli UTI89 attaching and effacing protein, pathogenesis factor YP_539353.1 331183 D 364106 CDS YP_539354.1 91209368 3990710 complement(335558..336448) 1 NC_007946.1 transcriptional regulator YkgA 336448 ykgA 3990710 ykgA Escherichia coli UTI89 transcriptional regulator YkgA YP_539354.1 335558 R 364106 CDS YP_539355.1 91209369 3990711 336648..337532 1 NC_007946.1 2,5-diketo-D-gluconate reductase A 337532 3990711 UTI89_C0323 Escherichia coli UTI89 2,5-diketo-D-gluconate reductase A YP_539355.1 336648 D 364106 CDS YP_539356.1 91209370 3990712 complement(337692..338294) 1 NC_007946.1 hypothetical protein 338294 ykgB 3990712 ykgB Escherichia coli UTI89 hypothetical protein YP_539356.1 337692 R 364106 CDS YP_539358.1 91209372 3990714 complement(338297..338548) 1 NC_007946.1 hypothetical protein 338548 ykgI 3990714 ykgI Escherichia coli UTI89 hypothetical protein YP_539358.1 338297 R 364106 CDS YP_539359.2 162138488 3990715 complement(338642..339967) 1 NC_007946.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 339967 ykgC 3990715 ykgC Escherichia coli UTI89 pyridine nucleotide-disulfide oxidoreductase YP_539359.2 338642 R 364106 CDS YP_539360.1 91209374 3990716 340143..341048 1 NC_007946.1 transcriptional regulator YkgD 341048 ykgD 3990716 ykgD Escherichia coli UTI89 transcriptional regulator YkgD YP_539360.1 340143 D 364106 CDS YP_539361.1 91209375 3990717 341575..342294 1 NC_007946.1 hypothetical protein 342294 ykgE 3990717 ykgE Escherichia coli UTI89 hypothetical protein YP_539361.1 341575 D 364106 CDS YP_539362.1 91209376 3990718 342305..343732 1 NC_007946.1 electron transport protein YkgF 343732 ykgF 3990718 ykgF Escherichia coli UTI89 electron transport protein YkgF YP_539362.1 342305 D 364106 CDS YP_539363.1 91209377 3990719 343572..344420 1 NC_007946.1 hypothetical protein 344420 ykgG 3990719 ykgG Escherichia coli UTI89 hypothetical protein YP_539363.1 343572 D 364106 CDS YP_539364.1 91209378 3990720 complement(344375..344587) 1 NC_007946.1 hypothetical protein 344587 3990720 UTI89_C0332 Escherichia coli UTI89 hypothetical protein YP_539364.1 344375 R 364106 CDS YP_539365.1 91209379 3990721 complement(344662..345330) 1 NC_007946.1 hypothetical protein 345330 ykgH 3990721 ykgH Escherichia coli UTI89 hypothetical protein YP_539365.1 344662 R 364106 CDS YP_539366.1 91209380 3990722 complement(345514..347844) 1 NC_007946.1 hypothetical protein 347844 3990722 UTI89_C0334 Escherichia coli UTI89 hypothetical protein YP_539366.1 345514 R 364106 CDS YP_539367.1 91209381 3990723 complement(347853..348614) 1 NC_007946.1 hypothetical protein 348614 3990723 UTI89_C0335 Escherichia coli UTI89 hypothetical protein YP_539367.1 347853 R 364106 CDS YP_539368.1 91209382 3990724 complement(348768..349472) 1 NC_007946.1 hypothetical protein 349472 3990724 UTI89_C0336 Escherichia coli UTI89 hypothetical protein YP_539368.1 348768 R 364106 CDS YP_539369.1 91209383 3990725 complement(349444..349599) 1 NC_007946.1 hypothetical protein 349599 3990725 UTI89_C0337 Escherichia coli UTI89 hypothetical protein YP_539369.1 349444 R 364106 CDS YP_539370.1 91209384 3990726 complement(349892..350494) 1 NC_007946.1 type 1 fimbriae regulatory protein FimX 350494 fimX 3990726 fimX Escherichia coli UTI89 type 1 fimbriae regulatory protein FimX YP_539370.1 349892 R 364106 CDS YP_539371.1 91209385 3990727 351273..351500 1 NC_007946.1 hypothetical protein 351500 3990727 UTI89_C0339 Escherichia coli UTI89 hypothetical protein YP_539371.1 351273 D 364106 CDS YP_539372.2 162138487 3990728 complement(351525..353213) 1 NC_007946.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 353213 betA 3990728 betA Escherichia coli UTI89 choline dehydrogenase YP_539372.2 351525 R 364106 CDS YP_539373.1 91209387 3990729 complement(353227..354702) 1 NC_007946.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 354702 betB 3990729 betB Escherichia coli UTI89 betaine aldehyde dehydrogenase YP_539373.1 353227 R 364106 CDS YP_539374.1 91209388 3992181 complement(354713..355318) 1 NC_007946.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 355318 betI 3992181 betI Escherichia coli UTI89 transcriptional regulator BetI YP_539374.1 354713 R 364106 CDS YP_539375.1 91209389 3992182 355429..357462 1 NC_007946.1 proton-motive-force-driven choline transporter; choline transport protein BetT 357462 betT 3992182 betT Escherichia coli UTI89 choline transport protein BetT YP_539375.1 355429 D 364106 CDS YP_539376.1 91209390 3992183 358334..359428 1 NC_007946.1 hypothetical protein 359428 yahA 3992183 yahA Escherichia coli UTI89 hypothetical protein YP_539376.1 358334 D 364106 CDS YP_539377.1 91209391 3992184 complement(359470..360402) 1 NC_007946.1 transcriptional regulator YahB 360402 yahB 3992184 yahB Escherichia coli UTI89 transcriptional regulator YahB YP_539377.1 359470 R 364106 CDS YP_539378.1 91209392 3992185 complement(360494..360991) 1 NC_007946.1 hypothetical protein 360991 yahC 3992185 yahC Escherichia coli UTI89 hypothetical protein YP_539378.1 360494 R 364106 CDS YP_539379.1 91209393 3992186 361068..361310 1 NC_007946.1 hypothetical protein 361310 3992186 UTI89_C0347 Escherichia coli UTI89 hypothetical protein YP_539379.1 361068 D 364106 CDS YP_539380.1 91209394 3992187 361249..361854 1 NC_007946.1 transcription factor 361854 yahD 3992187 yahD Escherichia coli UTI89 transcription factor YP_539380.1 361249 D 364106 CDS YP_539381.1 91209395 3992188 361894..362757 1 NC_007946.1 hypothetical protein 362757 yahE 3992188 yahE Escherichia coli UTI89 hypothetical protein YP_539381.1 361894 D 364106 CDS YP_539382.1 91209396 3992189 362747..364294 1 NC_007946.1 hypothetical protein 364294 yahF 3992189 yahF Escherichia coli UTI89 hypothetical protein YP_539382.1 362747 D 364106 CDS YP_539383.1 91209397 3992190 364294..365712 1 NC_007946.1 hypothetical protein 365712 yahG 3992190 yahG Escherichia coli UTI89 hypothetical protein YP_539383.1 364294 D 364106 CDS YP_539384.1 91209398 3992191 365866..366816 1 NC_007946.1 carbamate kinase 366816 yahI 3992191 yahI Escherichia coli UTI89 carbamate kinase YP_539384.1 365866 D 364106 CDS YP_539385.1 91209399 3992192 366826..368208 1 NC_007946.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 368208 yahJ 3992192 yahJ Escherichia coli UTI89 deaminase YP_539385.1 366826 D 364106 CDS YP_539386.1 91209400 3992193 368476..368916 1 NC_007946.1 hypothetical protein 368916 3992193 UTI89_C0354 Escherichia coli UTI89 hypothetical protein YP_539386.1 368476 D 364106 CDS YP_539387.1 91209401 3992194 369167..370153 1 NC_007946.1 periplasmic binding protein, substrate ribose 370153 3992194 UTI89_C0355 Escherichia coli UTI89 periplasmic binding protein, substrate ribose YP_539387.1 369167 D 364106 CDS YP_539388.1 91209402 3992195 370187..371686 1 NC_007946.1 ABC transporter ATP-binding protein 371686 3992195 UTI89_C0356 Escherichia coli UTI89 ABC transporter ATP-binding protein YP_539388.1 370187 D 364106 CDS YP_539389.1 91209403 3992196 371679..372650 1 NC_007946.1 permease 372650 3992196 UTI89_C0357 Escherichia coli UTI89 permease YP_539389.1 371679 D 364106 CDS YP_539390.1 91209404 3992197 372647..373603 1 NC_007946.1 permease 373603 3992197 UTI89_C0358 Escherichia coli UTI89 permease YP_539390.1 372647 D 364106 CDS YP_539391.1 91209405 3992198 373690..374739 1 NC_007946.1 zinc-type alcohol dehydrogenase-like protein YahK 374739 yahK 3992198 yahK Escherichia coli UTI89 zinc-type alcohol dehydrogenase-like protein YahK YP_539391.1 373690 D 364106 CDS YP_539392.1 91209406 3992199 375331..375606 1 NC_007946.1 hypothetical protein 375606 yahM 3992199 yahM Escherichia coli UTI89 hypothetical protein YP_539392.1 375331 D 364106 CDS YP_539393.1 91209407 3994383 complement(375623..376294) 1 NC_007946.1 cytochrome subunit of dehydrogenase 376294 yahN 3994383 yahN Escherichia coli UTI89 cytochrome subunit of dehydrogenase YP_539393.1 375623 R 364106 CDS YP_539394.1 91209408 3994384 376441..376716 1 NC_007946.1 hypothetical protein 376716 yahO 3994384 yahO Escherichia coli UTI89 hypothetical protein YP_539394.1 376441 D 364106 CDS YP_539395.1 91209409 3994385 378642..379532 1 NC_007946.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 379532 prpB 3994385 prpB Escherichia coli UTI89 2-methylisocitrate lyase YP_539395.1 378642 D 364106 CDS YP_539396.1 91209410 3994386 379577..380746 1 NC_007946.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 380746 prpC 3994386 prpC Escherichia coli UTI89 methylcitrate synthase YP_539396.1 379577 D 364106 CDS YP_539397.1 91209411 3994387 380780..382231 1 NC_007946.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 382231 prpD 3994387 prpD Escherichia coli UTI89 2-methylcitrate dehydratase YP_539397.1 380780 D 364106 CDS YP_539398.1 91209412 3994388 382271..384157 1 NC_007946.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 384157 prpE 3994388 prpE Escherichia coli UTI89 propionyl-CoA synthetase YP_539398.1 382271 D 364106 CDS YP_539399.1 91209413 3994389 384482..385741 1 NC_007946.1 cytosine permease 385741 codB 3994389 codB Escherichia coli UTI89 cytosine permease YP_539399.1 384482 D 364106 CDS YP_539400.1 91209414 3994390 385716..387014 1 NC_007946.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 387014 codA 3994390 codA Escherichia coli UTI89 cytosine deaminase YP_539400.1 385716 D 364106 CDS YP_539401.1 91209415 3994391 complement(387135..387797) 1 NC_007946.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 387797 lacA 3994391 lacA Escherichia coli UTI89 galactoside O-acetyltransferase YP_539401.1 387135 R 364106 CDS YP_539402.1 91209416 3994392 complement(387812..389065) 1 NC_007946.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 389065 lacY 3994392 lacY Escherichia coli UTI89 galactoside permease YP_539402.1 387812 R 364106 CDS YP_539403.1 91209417 3994393 complement(389117..392191) 1 NC_007946.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 392191 lacZ 3994393 lacZ Escherichia coli UTI89 beta-D-galactosidase YP_539403.1 389117 R 364106 CDS YP_539404.1 91209418 3994394 complement(392314..393405) 1 NC_007946.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 393405 lacI 3994394 lacI Escherichia coli UTI89 lac repressor YP_539404.1 392314 R 364106 CDS YP_539405.1 91209419 3994395 complement(393433..393531) 1 NC_007946.1 AraC family transcriptional regulator 393531 3994395 UTI89_C0373 Escherichia coli UTI89 AraC family transcriptional regulator YP_539405.1 393433 R 364106 CDS YP_539406.1 91209420 3994396 393598..394137 1 NC_007946.1 hypothetical protein 394137 3994396 UTI89_C0374 Escherichia coli UTI89 hypothetical protein YP_539406.1 393598 D 364106 CDS YP_539407.1 91209421 3994397 complement(394363..395196) 1 NC_007946.1 hypothetical protein 395196 yaiM 3994397 yaiM Escherichia coli UTI89 hypothetical protein YP_539407.1 394363 R 364106 CDS YP_539408.1 91209422 3994398 complement(395289..396398) 1 NC_007946.1 alcohol dehydrogenase 396398 adhC 3994398 adhC Escherichia coli UTI89 alcohol dehydrogenase YP_539408.1 395289 R 364106 CDS YP_539409.1 91209423 3994399 complement(396433..396729) 1 NC_007946.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 396729 yaiN 3994399 yaiN Escherichia coli UTI89 regulator protein FrmR YP_539409.1 396433 R 364106 CDS YP_539410.1 91209424 3994400 396478..396780 1 NC_007946.1 hypothetical protein 396780 3994400 UTI89_C0378 Escherichia coli UTI89 hypothetical protein YP_539410.1 396478 D 364106 CDS YP_539411.1 91209425 3994401 complement(396897..397670) 1 NC_007946.1 hypothetical protein 397670 yaiO 3994401 yaiO Escherichia coli UTI89 hypothetical protein YP_539411.1 396897 R 364106 CDS YP_539412.1 91209426 3994402 complement(397672..398196) 1 NC_007946.1 transferase 398196 3994402 UTI89_C0380 Escherichia coli UTI89 transferase YP_539412.1 397672 R 364106 CDS YP_539413.1 91209427 3992313 complement(398231..399427) 1 NC_007946.1 hypothetical protein 399427 yaiP 3992313 yaiP Escherichia coli UTI89 hypothetical protein YP_539413.1 398231 R 364106 CDS YP_539414.1 91209428 3992314 complement(399437..400123) 1 NC_007946.1 hypothetical protein 400123 3992314 UTI89_C0382 Escherichia coli UTI89 hypothetical protein YP_539414.1 399437 R 364106 CDS YP_539415.1 91209429 3992315 complement(400568..400762) 1 NC_007946.1 hypothetical protein 400762 3992315 UTI89_C0383 Escherichia coli UTI89 hypothetical protein YP_539415.1 400568 R 364106 CDS YP_539416.2 162138486 3992316 400716..401678 1 NC_007946.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 401678 tauA 3992316 tauA Escherichia coli UTI89 taurine transporter substrate binding subunit YP_539416.2 400716 D 364106 CDS YP_539417.1 91209431 3992317 401691..402458 1 NC_007946.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine ABC transporter ATP-binding protein 402458 tauB 3992317 tauB Escherichia coli UTI89 taurine ABC transporter ATP-binding protein YP_539417.1 401691 D 364106 CDS YP_539418.1 91209432 3992318 402455..403282 1 NC_007946.1 taurine ABC transporter 403282 tauC 3992318 tauC Escherichia coli UTI89 taurine ABC transporter YP_539418.1 402455 D 364106 CDS YP_539419.1 91209433 3992319 403279..404130 1 NC_007946.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 404130 tauD 3992319 tauD Escherichia coli UTI89 taurine dioxygenase YP_539419.1 403279 D 364106 CDS YP_539420.1 91209434 3992320 complement(404170..405177) 1 NC_007946.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 405177 hemB 3992320 hemB Escherichia coli UTI89 delta-aminolevulinic acid dehydratase YP_539420.1 404170 R 364106 CDS YP_539421.1 91209435 3992321 405670..408657 1 NC_007946.1 structural protein 408657 3992321 UTI89_C0389 Escherichia coli UTI89 structural protein YP_539421.1 405670 D 364106 CDS YP_539422.1 91209436 3992322 408698..409366 1 NC_007946.1 DNA-binding transcriptional regulator 409366 yaiV 3992322 yaiV Escherichia coli UTI89 DNA-binding transcriptional regulator YP_539422.1 408698 D 364106 CDS YP_539423.1 91209437 3992323 complement(409367..410524) 1 NC_007946.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 410524 yaiH 3992323 yaiH Escherichia coli UTI89 beta-lactam binding protein AmpH YP_539423.1 409367 R 364106 CDS YP_539424.1 91209438 3992324 410662..410856 1 NC_007946.1 hypothetical protein 410856 3992324 UTI89_C0392 Escherichia coli UTI89 hypothetical protein YP_539424.1 410662 D 364106 CDS YP_539425.1 91209439 3992325 410870..412096 1 NC_007946.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 412096 sbmA 3992325 sbmA Escherichia coli UTI89 transport protein YP_539425.1 410870 D 364106 CDS YP_539426.1 91209440 3992326 412109..413203 1 NC_007946.1 hypothetical protein 413203 yaiW 3992326 yaiW Escherichia coli UTI89 hypothetical protein YP_539426.1 412109 D 364106 CDS YP_539427.1 91209441 3992327 complement(413262..413570) 1 NC_007946.1 hypothetical protein 413570 yaiY 3992327 yaiY Escherichia coli UTI89 hypothetical protein YP_539427.1 413262 R 364106 CDS YP_539428.1 91209442 3992328 413500..413634 1 NC_007946.1 hypothetical protein 413634 3992328 UTI89_C0396 Escherichia coli UTI89 hypothetical protein YP_539428.1 413500 D 364106 CDS YP_539429.1 91209443 3992329 413698..414042 1 NC_007946.1 hypothetical protein 414042 yaiZ 3992329 yaiZ Escherichia coli UTI89 hypothetical protein YP_539429.1 413698 D 364106 CDS YP_539430.1 91209444 3992330 complement(414066..415160) 1 NC_007946.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 415160 ddl 3992330 ddl Escherichia coli UTI89 D-alanyl-alanine synthetase A YP_539430.1 414066 R 364106 CDS YP_539431.1 91209445 3992331 415238..415360 1 NC_007946.1 hypothetical protein 415360 3992331 UTI89_C0399 Escherichia coli UTI89 hypothetical protein YP_539431.1 415238 D 364106 CDS YP_539432.1 91209446 3993501 complement(415475..415738) 1 NC_007946.1 hypothetical protein 415738 3993501 UTI89_C0400 Escherichia coli UTI89 hypothetical protein YP_539432.1 415475 R 364106 CDS YP_539433.1 91209447 3993502 415623..415883 1 NC_007946.1 hypothetical protein 415883 yaiB 3993502 yaiB Escherichia coli UTI89 hypothetical protein YP_539433.1 415623 D 364106 CDS YP_539434.1 91209448 3993503 415915..417399 1 NC_007946.1 alkaline phosphatase 417399 phoA 3993503 phoA Escherichia coli UTI89 alkaline phosphatase YP_539434.1 415915 D 364106 CDS YP_539435.1 91209449 3993504 417500..417838 1 NC_007946.1 hypothetical protein 417838 psiF 3993504 psiF Escherichia coli UTI89 hypothetical protein YP_539435.1 417500 D 364106 CDS YP_539436.1 91209450 3993505 417940..419055 1 NC_007946.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 419055 adrA 3993505 adrA Escherichia coli UTI89 diguanylate cyclase AdrA YP_539436.1 417940 D 364106 CDS YP_539437.2 162138485 3993506 complement(419072..419881) 1 NC_007946.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 419881 proC 3993506 proC Escherichia coli UTI89 pyrroline-5-carboxylate reductase YP_539437.2 419072 R 364106 CDS YP_539438.1 91209452 3993507 419881..420459 1 NC_007946.1 hypothetical protein 420459 yaiI 3993507 yaiI Escherichia coli UTI89 hypothetical protein YP_539438.1 419881 D 364106 CDS YP_539439.1 91209453 3993508 420642..421166 1 NC_007946.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 421166 aroL 3993508 aroL Escherichia coli UTI89 shikimate kinase II YP_539439.1 420642 D 364106 CDS YP_539440.1 91209454 3993509 complement(421156..421488) 1 NC_007946.1 hypothetical protein 421488 3993509 UTI89_C0408 Escherichia coli UTI89 hypothetical protein YP_539440.1 421156 R 364106 CDS YP_539441.1 91209455 3993510 421216..421407 1 NC_007946.1 hypothetical protein 421407 yaiA 3993510 yaiA Escherichia coli UTI89 hypothetical protein YP_539441.1 421216 D 364106 CDS YP_539442.1 91209456 3993511 421665..422342 1 NC_007946.1 hypothetical protein 422342 aroM 3993511 aroM Escherichia coli UTI89 hypothetical protein YP_539442.1 421665 D 364106 CDS YP_539443.1 91209457 3993512 422414..422698 1 NC_007946.1 hypothetical protein 422698 yaiE 3993512 yaiE Escherichia coli UTI89 hypothetical protein YP_539443.1 422414 D 364106 CDS YP_539444.1 91209458 3993513 complement(422802..422957) 1 NC_007946.1 hypothetical protein 422957 3993513 UTI89_C0412 Escherichia coli UTI89 hypothetical protein YP_539444.1 422802 R 364106 CDS YP_539445.1 91209459 3993514 422906..423187 1 NC_007946.1 hypothetical protein 423187 ykiA 3993514 ykiA Escherichia coli UTI89 hypothetical protein YP_539445.1 422906 D 364106 CDS YP_539446.2 162138484 3993515 complement(423345..424256) 1 NC_007946.1 Required for efficient pilin antigenic variation; recombination associated protein 424256 rdgC 3993515 rdgC Escherichia coli UTI89 recombination associated protein YP_539446.2 423345 R 364106 CDS YP_539447.2 162138483 3993516 424381..425289 1 NC_007946.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 425289 yajF 3993516 yajF Escherichia coli UTI89 fructokinase YP_539447.2 424381 D 364106 CDS YP_539448.1 91209462 3993517 complement(425558..426826) 1 NC_007946.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 426826 araJ 3993517 araJ Escherichia coli UTI89 MFS transport protein AraJ YP_539448.1 425558 R 364106 CDS YP_539449.1 91209463 3993518 complement(426868..430011) 1 NC_007946.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC 430011 sbcC 3993518 sbcC Escherichia coli UTI89 exonuclease SbcC YP_539449.1 426868 R 364106 CDS YP_539450.1 91209464 3993519 complement(430008..431210) 1 NC_007946.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD 431210 sbcD 3993519 sbcD Escherichia coli UTI89 exonuclease SbcD YP_539450.1 430008 R 364106 CDS YP_539451.1 91209465 3993520 431196..431327 1 NC_007946.1 hypothetical protein 431327 3993520 UTI89_C0419 Escherichia coli UTI89 hypothetical protein YP_539451.1 431196 D 364106 CDS YP_539452.1 91209466 3993718 431400..432089 1 NC_007946.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 432089 phoB 3993718 phoB Escherichia coli UTI89 transcriptional regulator PhoB YP_539452.1 431400 D 364106 CDS YP_539453.1 91209467 3993719 432147..433442 1 NC_007946.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 433442 phoR 3993719 phoR Escherichia coli UTI89 phosphate regulon sensor protein YP_539453.1 432147 D 364106 CDS YP_539454.1 91209468 3993720 complement(433655..433804) 1 NC_007946.1 hypothetical protein 433804 3993720 UTI89_C0422 Escherichia coli UTI89 hypothetical protein YP_539454.1 433655 R 364106 CDS YP_539455.1 91209469 3993721 433849..435168 1 NC_007946.1 branched-chain amino acid transport system II carrier protein 435168 brnQ 3993721 brnQ Escherichia coli UTI89 branched-chain amino acid transport system II carrier protein YP_539455.1 433849 D 364106 CDS YP_539456.1 91209470 3993722 435241..436617 1 NC_007946.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; permease 436617 proY 3993722 proY Escherichia coli UTI89 permease YP_539456.1 435241 D 364106 CDS YP_539457.1 91209471 3993723 436773..438590 1 NC_007946.1 maltodextrin glucosidase 438590 malZ 3993723 malZ Escherichia coli UTI89 maltodextrin glucosidase YP_539457.1 436773 D 364106 CDS YP_539458.2 162138482 3993724 complement(438595..439176) 1 NC_007946.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase 439176 yajB 3993724 yajB Escherichia coli UTI89 ACP phosphodieterase YP_539458.2 438595 R 364106 CDS YP_539459.1 91209473 3993725 439395..440465 1 NC_007946.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 440465 queA 3993725 queA Escherichia coli UTI89 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_539459.1 439395 D 364106 CDS YP_539460.1 91209474 3993726 440520..441647 1 NC_007946.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 441647 tgt 3993726 tgt Escherichia coli UTI89 queuine tRNA-ribosyltransferase YP_539460.1 440520 D 364106 CDS YP_539461.2 162138481 3993727 441670..442002 1 NC_007946.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 442002 yajC 3993727 yajC Escherichia coli UTI89 preprotein translocase subunit YajC YP_539461.2 441670 D 364106 CDS YP_539462.1 91209476 3993728 442030..443877 1 NC_007946.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 443877 secD 3993728 secD Escherichia coli UTI89 preprotein translocase subunit SecD YP_539462.1 442030 D 364106 CDS YP_539463.1 91209477 3993729 443843..444859 1 NC_007946.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 444859 secF 3993729 secF Escherichia coli UTI89 preprotein translocase subunit SecF YP_539463.1 443843 D 364106 CDS YP_539464.1 91209478 3993730 444920..445336 1 NC_007946.1 hypothetical protein 445336 yajD 3993730 yajD Escherichia coli UTI89 hypothetical protein YP_539464.1 444920 D 364106 CDS YP_539465.1 91209479 3993731 complement(445374..446306) 1 NC_007946.1 nucleoside channel phage T6/colicin K receptor 446306 tsx 3993731 tsx Escherichia coli UTI89 nucleoside channel phage T6/colicin K receptor YP_539465.1 445374 R 364106 CDS YP_539466.2 162138480 3993732 complement(446556..447095) 1 NC_007946.1 hypothetical protein 447095 yajI 3993732 yajI Escherichia coli UTI89 hypothetical protein YP_539466.2 446556 R 364106 CDS YP_539467.1 91209481 3993733 447246..447695 1 NC_007946.1 transcriptional regulator NrdR 447695 nrdR 3993733 nrdR Escherichia coli UTI89 transcriptional regulator NrdR YP_539467.1 447246 D 364106 CDS YP_539468.1 91209482 3993734 447699..448802 1 NC_007946.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 448802 ribD 3993734 ribD Escherichia coli UTI89 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_539468.1 447699 D 364106 CDS YP_539469.2 162138479 3993735 448891..449361 1 NC_007946.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 449361 ribH 3993735 ribH Escherichia coli UTI89 6,7-dimethyl-8-ribityllumazine synthase YP_539469.2 448891 D 364106 CDS YP_539470.1 91209484 3993736 complement(449351..449884) 1 NC_007946.1 hypothetical protein 449884 3993736 UTI89_C0438 Escherichia coli UTI89 hypothetical protein YP_539470.1 449351 R 364106 CDS YP_539471.1 91209485 3993082 449381..449800 1 NC_007946.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 449800 nusB 3993082 nusB Escherichia coli UTI89 transcription antitermination protein NusB YP_539471.1 449381 D 364106 CDS YP_539472.1 91209486 3993083 449878..450855 1 NC_007946.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 450855 thiL 3993083 thiL Escherichia coli UTI89 thiamine monophosphate kinase YP_539472.1 449878 D 364106 CDS YP_539473.1 91209487 3993084 450833..451351 1 NC_007946.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 451351 pgpA 3993084 pgpA Escherichia coli UTI89 phosphatidylglycerophosphatase A YP_539473.1 450833 D 364106 CDS YP_539474.1 91209488 3993085 complement(451405..452379) 1 NC_007946.1 oxidoreductase YajO 452379 yajO 3993085 yajO Escherichia coli UTI89 oxidoreductase YajO YP_539474.1 451405 R 364106 CDS YP_539475.1 91209489 3993086 complement(452434..454296) 1 NC_007946.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 454296 dxs 3993086 dxs Escherichia coli UTI89 1-deoxy-D-xylulose-5-phosphate synthase YP_539475.1 452434 R 364106 CDS YP_539476.1 91209490 3993087 complement(454321..455220) 1 NC_007946.1 geranyltranstransferase 455220 ispA 3993087 ispA Escherichia coli UTI89 geranyltranstransferase YP_539476.1 454321 R 364106 CDS YP_539477.1 91209491 3993088 complement(455220..455462) 1 NC_007946.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 455462 xseB 3993088 xseB Escherichia coli UTI89 exodeoxyribonuclease VII small subunit YP_539477.1 455220 R 364106 CDS YP_539478.1 91209492 3993089 455668..457116 1 NC_007946.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 457116 yajK 3993089 yajK Escherichia coli UTI89 thiamine biosynthesis protein ThiI YP_539478.1 455668 D 364106 CDS YP_539479.1 91209493 3993090 complement(457170..457766) 1 NC_007946.1 DJ-1 family protein 457766 thiJ 3993090 thiJ Escherichia coli UTI89 DJ-1 family protein YP_539479.1 457170 R 364106 CDS YP_539480.1 91209494 3993091 complement(457723..458634) 1 NC_007946.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 458634 apbA 3993091 apbA Escherichia coli UTI89 2-dehydropantoate 2-reductase YP_539480.1 457723 R 364106 CDS YP_539481.1 91209495 3993092 458634..459293 1 NC_007946.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 459293 yajQ 3993092 yajQ Escherichia coli UTI89 nucleotide-binding protein YP_539481.1 458634 D 364106 CDS YP_539482.1 91209496 3993093 complement(459421..460983) 1 NC_007946.1 transport protein YajR 460983 yajR 3993093 yajR Escherichia coli UTI89 transport protein YajR YP_539482.1 459421 R 364106 CDS YP_539483.1 91209497 3993094 complement(460934..461869) 1 NC_007946.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 461869 cyoE 3993094 cyoE Escherichia coli UTI89 protoheme IX farnesyltransferase YP_539483.1 460934 R 364106 CDS YP_539484.1 91209498 3993095 complement(461836..462165) 1 NC_007946.1 cytochrome o ubiquinol oxidase subunit IV 462165 cyoD 3993095 cyoD Escherichia coli UTI89 cytochrome o ubiquinol oxidase subunit IV YP_539484.1 461836 R 364106 CDS YP_539485.1 91209499 3993096 461858..462115 1 NC_007946.1 hypothetical protein 462115 3993096 UTI89_C0453 Escherichia coli UTI89 hypothetical protein YP_539485.1 461858 D 364106 CDS YP_539486.1 91209500 3993097 complement(462165..462779) 1 NC_007946.1 cytochrome o ubiquinol oxidase subunit III 462779 cyoC 3993097 cyoC Escherichia coli UTI89 cytochrome o ubiquinol oxidase subunit III YP_539486.1 462165 R 364106 CDS YP_539487.1 91209501 3993098 complement(462769..464760) 1 NC_007946.1 cytochrome o ubiquinol oxidase subunit I 464760 cyoB 3993098 cyoB Escherichia coli UTI89 cytochrome o ubiquinol oxidase subunit I YP_539487.1 462769 R 364106 CDS YP_539488.1 91209502 3993099 complement(464782..465729) 1 NC_007946.1 cytochrome o ubiquinol oxidase subunit II 465729 cyoA 3993099 cyoA Escherichia coli UTI89 cytochrome o ubiquinol oxidase subunit II YP_539488.1 464782 R 364106 CDS YP_539489.1 91209503 3993100 complement(466188..467663) 1 NC_007946.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 467663 ampG 3993100 ampG Escherichia coli UTI89 muropeptide transporter YP_539489.1 466188 R 364106 CDS YP_539490.2 162138478 3993101 complement(467707..468285) 1 NC_007946.1 hypothetical protein 468285 yajG 3993101 yajG Escherichia coli UTI89 hypothetical protein YP_539490.2 467707 R 364106 CDS YP_539491.1 91209505 3990404 complement(468347..468466) 1 NC_007946.1 hypothetical protein 468466 3990404 UTI89_C0459 Escherichia coli UTI89 hypothetical protein YP_539491.1 468347 R 364106 CDS YP_539492.2 162138477 3990405 468590..468907 1 NC_007946.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 468907 bolA 3990405 bolA Escherichia coli UTI89 transcriptional regulator BolA YP_539492.2 468590 D 364106 CDS YP_539493.1 91209507 3990406 complement(468834..469256) 1 NC_007946.1 hypothetical protein 469256 3990406 UTI89_C0461 Escherichia coli UTI89 hypothetical protein YP_539493.1 468834 R 364106 CDS YP_539494.1 91209508 3990407 468841..469104 1 NC_007946.1 hypothetical protein 469104 3990407 UTI89_C0462 Escherichia coli UTI89 hypothetical protein YP_539494.1 468841 D 364106 CDS YP_539495.1 91209509 3990408 469251..470540 1 NC_007946.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 470540 tig 3990408 tig Escherichia coli UTI89 trigger factor YP_539495.1 469251 D 364106 CDS YP_539496.1 91209510 3990409 complement(469260..470561) 1 NC_007946.1 hypothetical protein 470561 3990409 UTI89_C0464 Escherichia coli UTI89 hypothetical protein YP_539496.1 469260 R 364106 CDS YP_539497.1 91209511 3990410 470795..471418 1 NC_007946.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 471418 clpP 3990410 clpP Escherichia coli UTI89 ATP-dependent Clp protease proteolytic subunit YP_539497.1 470795 D 364106 CDS YP_539498.1 91209512 3990411 471544..472818 1 NC_007946.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 472818 clpX 3990411 clpX Escherichia coli UTI89 ATP-dependent protease ATP-binding subunit ClpX YP_539498.1 471544 D 364106 CDS YP_539499.1 91209513 3990412 472961..475360 1 NC_007946.1 DNA-binding ATP-dependent protease La 475360 lon 3990412 lon Escherichia coli UTI89 DNA-binding ATP-dependent protease La YP_539499.1 472961 D 364106 CDS YP_539500.1 91209514 3990413 475569..475841 1 NC_007946.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 475841 hupB 3990413 hupB Escherichia coli UTI89 transcriptional regulator HU subunit beta YP_539500.1 475569 D 364106 CDS YP_539501.1 91209515 3990414 476033..477904 1 NC_007946.1 peptidyl-prolyl cis-trans isomerase D 477904 ybaU 3990414 ybaU Escherichia coli UTI89 peptidyl-prolyl cis-trans isomerase D YP_539501.1 476033 D 364106 CDS YP_539502.1 91209516 3990415 478055..478426 1 NC_007946.1 hypothetical protein 478426 ybaV 3990415 ybaV Escherichia coli UTI89 hypothetical protein YP_539502.1 478055 D 364106 CDS YP_539503.1 91209517 3990416 478532..478930 1 NC_007946.1 hypothetical protein 478930 ybaW 3990416 ybaW Escherichia coli UTI89 hypothetical protein YP_539503.1 478532 D 364106 CDS YP_539504.1 91209518 3990417 complement(478982..479677) 1 NC_007946.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 479677 ybaX 3990417 ybaX Escherichia coli UTI89 queuosine biosynthesis protein QueC YP_539504.1 478982 R 364106 CDS YP_539505.1 91209519 3990418 complement(479742..481457) 1 NC_007946.1 hypothetical protein 481457 ybaE 3990418 ybaE Escherichia coli UTI89 hypothetical protein YP_539505.1 479742 R 364106 CDS YP_539506.1 91209520 3990419 481530..482360 1 NC_007946.1 hypothetical protein 482360 cof 3990419 cof Escherichia coli UTI89 hypothetical protein YP_539506.1 481530 D 364106 CDS YP_539507.1 91209521 3990420 482405..482971 1 NC_007946.1 transcriptional regulator YbaO 482971 ybaO 3990420 ybaO Escherichia coli UTI89 transcriptional regulator YbaO YP_539507.1 482405 D 364106 CDS YP_539508.1 91209522 3990421 483001..484773 1 NC_007946.1 multidrug ABC transporter ATP-binding protein 484773 mdlA 3990421 mdlA Escherichia coli UTI89 multidrug ABC transporter ATP-binding protein YP_539508.1 483001 D 364106 CDS YP_539509.1 91209523 3990422 484652..486547 1 NC_007946.1 multidrug ABC transporter ATP-binding protein 486547 mdlB 3990422 mdlB Escherichia coli UTI89 multidrug ABC transporter ATP-binding protein YP_539509.1 484652 D 364106 CDS YP_539510.1 91209524 3990151 486728..487066 1 NC_007946.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 487066 glnK 3990151 glnK Escherichia coli UTI89 nitrogen regulatory protein P-II 2 YP_539510.1 486728 D 364106 CDS YP_539511.1 91209525 3990152 487096..488382 1 NC_007946.1 ammonium transporter 488382 amtB 3990152 amtB Escherichia coli UTI89 ammonium transporter YP_539511.1 487096 D 364106 CDS YP_539512.1 91209526 3990153 complement(488431..489375) 1 NC_007946.1 acyl-CoA thioesterase 489375 tesB 3990153 tesB Escherichia coli UTI89 acyl-CoA thioesterase YP_539512.1 488431 R 364106 CDS YP_539513.1 91209527 3990154 489509..490081 1 NC_007946.1 hypothetical protein 490081 ybaY 3990154 ybaY Escherichia coli UTI89 hypothetical protein YP_539513.1 489509 D 364106 CDS YP_539514.1 91209528 3990155 complement(490112..490522) 1 NC_007946.1 hypothetical protein 490522 ybaZ 3990155 ybaZ Escherichia coli UTI89 hypothetical protein YP_539514.1 490112 R 364106 CDS YP_539515.1 91209529 3990156 490802..491155 1 NC_007946.1 hypothetical protein 491155 ybaA 3990156 ybaA Escherichia coli UTI89 hypothetical protein YP_539515.1 490802 D 364106 CDS YP_539516.1 91209530 3990157 complement(491197..492753) 1 NC_007946.1 hypothetical protein 492753 ylaB 3990157 ylaB Escherichia coli UTI89 hypothetical protein YP_539516.1 491197 R 364106 CDS YP_539517.1 91209531 3990158 complement(492911..493420) 1 NC_007946.1 hypothetical protein 493420 ylaC 3990158 ylaC Escherichia coli UTI89 hypothetical protein YP_539517.1 492911 R 364106 CDS YP_539518.1 91209532 3990159 complement(493497..494048) 1 NC_007946.1 maltose O-acetyltransferase 494048 maa 3990159 maa Escherichia coli UTI89 maltose O-acetyltransferase YP_539518.1 493497 R 364106 CDS YP_539519.1 91209533 3990160 complement(494222..494452) 1 NC_007946.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 494452 hha 3990160 hha Escherichia coli UTI89 hemolysin expression-modulating protein YP_539519.1 494222 R 364106 CDS YP_539520.1 91209534 3990161 complement(494466..494840) 1 NC_007946.1 hypothetical protein 494840 ybaJ 3990161 ybaJ Escherichia coli UTI89 hypothetical protein YP_539520.1 494466 R 364106 CDS YP_539521.1 91209535 3990162 complement(495385..498534) 1 NC_007946.1 acridine efflux pump 498534 acrB 3990162 acrB Escherichia coli UTI89 acridine efflux pump YP_539521.1 495385 R 364106 CDS YP_539522.1 91209536 3990163 complement(498557..499786) 1 NC_007946.1 acriflavine resistance protein A 499786 acrA 3990163 acrA Escherichia coli UTI89 acriflavine resistance protein A YP_539522.1 498557 R 364106 CDS YP_539523.1 91209537 3990164 499892..500539 1 NC_007946.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 500539 acrR 3990164 acrR Escherichia coli UTI89 DNA-binding transcriptional repressor AcrR YP_539523.1 499892 D 364106 CDS YP_539524.1 91209538 3990165 500667..504029 1 NC_007946.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 504029 kefA 3990165 kefA Escherichia coli UTI89 potassium efflux protein KefA YP_539524.1 500667 D 364106 CDS YP_539525.1 91209539 3990166 complement(504241..504402) 1 NC_007946.1 hypothetical protein 504402 ybaM 3990166 ybaM Escherichia coli UTI89 hypothetical protein YP_539525.1 504241 R 364106 CDS YP_539526.1 91209540 3990167 complement(504416..504943) 1 NC_007946.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 504943 priC 3990167 priC Escherichia coli UTI89 primosomal replication protein N'' YP_539526.1 504416 R 364106 CDS YP_539527.1 91209541 3990168 505013..505390 1 NC_007946.1 hypothetical protein 505390 ybaN 3990168 ybaN Escherichia coli UTI89 hypothetical protein YP_539527.1 505013 D 364106 CDS YP_539528.1 91209542 3990169 505489..506094 1 NC_007946.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 506094 apt 3990169 apt Escherichia coli UTI89 adenine phosphoribosyltransferase YP_539528.1 505489 D 364106 CDS YP_539529.1 91209543 3990170 506223..508154 1 NC_007946.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 508154 dnaX 3990170 dnaX Escherichia coli UTI89 DNA polymerase III subunits gamma and tau YP_539529.1 506223 D 364106 CDS YP_539530.1 91209544 3991666 complement(508183..508560) 1 NC_007946.1 hypothetical protein 508560 3991666 UTI89_C0498 Escherichia coli UTI89 hypothetical protein YP_539530.1 508183 R 364106 CDS YP_539531.1 91209545 3991667 508192..508536 1 NC_007946.1 hypothetical protein 508536 ybaB 3991667 ybaB Escherichia coli UTI89 hypothetical protein YP_539531.1 508192 D 364106 CDS YP_539532.1 91209546 3991668 508536..509141 1 NC_007946.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 509141 recR 3991668 recR Escherichia coli UTI89 recombination protein RecR YP_539532.1 508536 D 364106 CDS YP_539533.1 91209547 3991669 509251..511125 1 NC_007946.1 molecular chaperone; heat shock protein 90 511125 htpG 3991669 htpG Escherichia coli UTI89 heat shock protein 90 YP_539533.1 509251 D 364106 CDS YP_539534.1 91209548 3991670 511246..511950 1 NC_007946.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 511950 adk 3991670 adk Escherichia coli UTI89 adenylate kinase YP_539534.1 511246 D 364106 CDS YP_539535.1 91209549 3991671 512082..513044 1 NC_007946.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 513044 hemH 3991671 hemH Escherichia coli UTI89 ferrochelatase YP_539535.1 512082 D 364106 CDS YP_539536.1 91209550 3991672 complement(513041..514000) 1 NC_007946.1 acetyl esterase 514000 ybaC 3991672 ybaC Escherichia coli UTI89 acetyl esterase YP_539536.1 513041 R 364106 CDS YP_539537.1 91209551 3991673 514152..515456 1 NC_007946.1 inosine-guanosine kinase 515456 gsk 3991673 gsk Escherichia coli UTI89 inosine-guanosine kinase YP_539537.1 514152 D 364106 CDS YP_539538.1 91209552 3991674 complement(515586..517262) 1 NC_007946.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 517262 ybaL 3991674 ybaL Escherichia coli UTI89 cation:proton antiport protein YP_539538.1 515586 R 364106 CDS YP_539539.1 91209553 3991675 complement(517501..518721) 1 NC_007946.1 fosmidomycin resistance protein 518721 fsr 3991675 fsr Escherichia coli UTI89 fosmidomycin resistance protein YP_539539.1 517501 R 364106 CDS YP_539540.1 91209554 3991676 518939..520591 1 NC_007946.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase 520591 ushA 3991676 ushA Escherichia coli UTI89 bifunctional UDP-sugar hydrolase/5'-nucleotidase YP_539540.1 518939 D 364106 CDS YP_539541.1 91209555 3991677 complement(520629..521132) 1 NC_007946.1 hypothetical protein 521132 3991677 UTI89_C0509 Escherichia coli UTI89 hypothetical protein YP_539541.1 520629 R 364106 CDS YP_539542.1 91209556 3991678 complement(521129..521785) 1 NC_007946.1 hypothetical protein 521785 3991678 UTI89_C0510 Escherichia coli UTI89 hypothetical protein YP_539542.1 521129 R 364106 CDS YP_539543.1 91209557 3991679 complement(521953..522432) 1 NC_007946.1 hypothetical protein 522432 ybaK 3991679 ybaK Escherichia coli UTI89 hypothetical protein YP_539543.1 521953 R 364106 CDS YP_539544.1 91209558 3991680 complement(522636..523430) 1 NC_007946.1 ligase 523430 ybaP 3991680 ybaP Escherichia coli UTI89 ligase YP_539544.1 522636 R 364106 CDS YP_539545.1 91209559 3991681 523533..523865 1 NC_007946.1 hypothetical protein 523865 3991681 UTI89_C0513 Escherichia coli UTI89 hypothetical protein YP_539545.1 523533 D 364106 CDS YP_539546.1 91209560 3991682 523901..524242 1 NC_007946.1 hypothetical protein 524242 3991682 UTI89_C0514 Escherichia coli UTI89 hypothetical protein YP_539546.1 523901 D 364106 CDS YP_539547.1 91209561 3991683 complement(524300..526804) 1 NC_007946.1 copper exporting ATPase 526804 copA 3991683 copA Escherichia coli UTI89 copper exporting ATPase YP_539547.1 524300 R 364106 CDS YP_539548.1 91209562 3991684 527066..527998 1 NC_007946.1 catalyzes the formation of glutamate from glutamine; glutaminase 527998 ybaS 3991684 ybaS Escherichia coli UTI89 glutaminase YP_539548.1 527066 D 364106 CDS YP_539549.1 91209563 3991610 528001..529293 1 NC_007946.1 transport protein YbaT 529293 ybaT 3991610 ybaT Escherichia coli UTI89 transport protein YbaT YP_539549.1 528001 D 364106 CDS YP_539550.1 91209564 3991611 529418..529825 1 NC_007946.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 529825 cueR 3991611 cueR Escherichia coli UTI89 DNA-binding transcriptional regulator CueR YP_539550.1 529418 D 364106 CDS YP_539551.1 91209565 3991612 complement(529829..529996) 1 NC_007946.1 hypothetical protein 529996 3991612 UTI89_C0519 Escherichia coli UTI89 hypothetical protein YP_539551.1 529829 R 364106 CDS YP_539552.1 91209566 3991613 complement(530029..530451) 1 NC_007946.1 hypothetical protein 530451 3991613 UTI89_C0520 Escherichia coli UTI89 hypothetical protein YP_539552.1 530029 R 364106 CDS YP_539553.1 91209567 3991614 complement(530537..531553) 1 NC_007946.1 adhesin 531553 3991614 UTI89_C0521 Escherichia coli UTI89 adhesin YP_539553.1 530537 R 364106 CDS YP_539554.1 91209568 3991615 531920..532282 1 NC_007946.1 hypothetical protein 532282 3991615 UTI89_C0522 Escherichia coli UTI89 hypothetical protein YP_539554.1 531920 D 364106 CDS YP_539555.1 91209569 3991616 complement(532385..532843) 1 NC_007946.1 hypothetical protein 532843 ybbJ 3991616 ybbJ Escherichia coli UTI89 hypothetical protein YP_539555.1 532385 R 364106 CDS YP_539556.1 91209570 3991617 complement(532840..533757) 1 NC_007946.1 protease YbbK 533757 ybbK 3991617 ybbK Escherichia coli UTI89 protease YbbK YP_539556.1 532840 R 364106 CDS YP_539557.1 91209571 3991618 533903..534580 1 NC_007946.1 ABC transporter ATP-binding protein 534580 ybbL 3991618 ybbL Escherichia coli UTI89 ABC transporter ATP-binding protein YP_539557.1 533903 D 364106 CDS YP_539558.1 91209572 3991619 534540..535346 1 NC_007946.1 metal resistance protein 535346 ybbM 3991619 ybbM Escherichia coli UTI89 metal resistance protein YP_539558.1 534540 D 364106 CDS YP_539559.1 91209573 3991620 complement(535409..536299) 1 NC_007946.1 thioredoxin-like protein 536299 ybbN 3991620 ybbN Escherichia coli UTI89 thioredoxin-like protein YP_539559.1 535409 R 364106 CDS YP_539560.1 91209574 3991621 complement(536324..537133) 1 NC_007946.1 short chain dehydrogenase 537133 ybbO 3991621 ybbO Escherichia coli UTI89 short chain dehydrogenase YP_539560.1 536324 R 364106 CDS YP_539561.1 91209575 3991622 complement(537123..537779) 1 NC_007946.1 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 537779 tesA 3991622 tesA Escherichia coli UTI89 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 YP_539561.1 537123 R 364106 CDS YP_539562.1 91209576 3991623 537717..538403 1 NC_007946.1 ABC transporter ATP-binding protein 538403 ybbA 3991623 ybbA Escherichia coli UTI89 ABC transporter ATP-binding protein YP_539562.1 537717 D 364106 CDS YP_539563.1 91209577 3991624 538400..540814 1 NC_007946.1 hypothetical protein 540814 ybbP 3991624 ybbP Escherichia coli UTI89 hypothetical protein YP_539563.1 538400 D 364106 CDS YP_539564.1 91209578 3991625 complement(540873..541967) 1 NC_007946.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 541967 ybbB 3991625 ybbB Escherichia coli UTI89 tRNA 2-selenouridine synthase YP_539564.1 540873 R 364106 CDS YP_539565.1 91209579 3991626 complement(542036..542962) 1 NC_007946.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 542962 ybbS 3991626 ybbS Escherichia coli UTI89 DNA-binding transcriptional activator AllS YP_539565.1 542036 R 364106 CDS YP_539566.1 91209580 3991627 543192..543674 1 NC_007946.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 543674 ybbT 3991627 ybbT Escherichia coli UTI89 ureidoglycolate hydrolase YP_539566.1 543192 D 364106 CDS YP_539567.1 91209581 3991628 543752..544567 1 NC_007946.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 544567 ybbU 3991628 ybbU Escherichia coli UTI89 DNA-binding transcriptional repressor AllR YP_539567.1 543752 D 364106 CDS YP_539568.2 162138476 3991629 544657..546438 1 NC_007946.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 546438 gcl 3991629 gcl Escherichia coli UTI89 glyoxylate carboligase YP_539568.2 544657 D 364106 CDS YP_539569.1 91209583 3991299 546451..547227 1 NC_007946.1 hydroxypyruvate isomerase 547227 hyi 3991299 hyi Escherichia coli UTI89 hydroxypyruvate isomerase YP_539569.1 546451 D 364106 CDS YP_539570.1 91209584 3991300 547327..548205 1 NC_007946.1 2-hydroxy-3-oxopropionate reductase 548205 ybbQ 3991300 ybbQ Escherichia coli UTI89 2-hydroxy-3-oxopropionate reductase YP_539570.1 547327 D 364106 CDS YP_539571.1 91209585 3991301 548375..549829 1 NC_007946.1 allantoin permease 549829 ybbW 3991301 ybbW Escherichia coli UTI89 allantoin permease YP_539571.1 548375 D 364106 CDS YP_539572.1 91209586 3991302 549889..551250 1 NC_007946.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 551250 ybbX 3991302 ybbX Escherichia coli UTI89 allantoinase YP_539572.1 549889 D 364106 CDS YP_539573.1 91209587 3991303 551300..552607 1 NC_007946.1 purine permease YbbY 552607 ybbY 3991303 ybbY Escherichia coli UTI89 purine permease YbbY YP_539573.1 551300 D 364106 CDS YP_539574.1 91209588 3991304 552623..553774 1 NC_007946.1 glycerate kinase II 553774 ybbZ 3991304 ybbZ Escherichia coli UTI89 glycerate kinase II YP_539574.1 552623 D 364106 CDS YP_539575.1 91209589 3991305 complement(553903..554688) 1 NC_007946.1 hypothetical protein 554688 ylbA 3991305 ylbA Escherichia coli UTI89 hypothetical protein YP_539575.1 553903 R 364106 CDS YP_539576.1 91209590 3991306 complement(554699..555952) 1 NC_007946.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 555952 ylbB 3991306 ylbB Escherichia coli UTI89 allantoate amidohydrolase YP_539576.1 554699 R 364106 CDS YP_539577.1 91209591 3991307 complement(555956..557005) 1 NC_007946.1 ureidoglycolate dehydrogenase 557005 allD 3991307 allD Escherichia coli UTI89 ureidoglycolate dehydrogenase YP_539577.1 555956 R 364106 CDS YP_539578.1 91209592 3991308 557322..558989 1 NC_007946.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 558989 fdrA 3991308 fdrA Escherichia coli UTI89 membrane protein FdrA YP_539578.1 557322 D 364106 CDS YP_539579.1 91209593 3991309 558999..560258 1 NC_007946.1 hypothetical protein 560258 ylbE 3991309 ylbE Escherichia coli UTI89 hypothetical protein YP_539579.1 558999 D 364106 CDS YP_539580.1 91209594 3991310 560176..561084 1 NC_007946.1 hypothetical protein 561084 ylbF 3991310 ylbF Escherichia coli UTI89 hypothetical protein YP_539580.1 560176 D 364106 CDS YP_539581.1 91209595 3991311 561081..561974 1 NC_007946.1 carbamate kinase 561974 arcC 3991311 arcC Escherichia coli UTI89 carbamate kinase YP_539581.1 561081 D 364106 CDS YP_539582.1 91209596 3991312 complement(562127..563194) 1 NC_007946.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 563194 purK 3991312 purK Escherichia coli UTI89 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_539582.1 562127 R 364106 CDS YP_539583.1 91209597 3991313 complement(563191..563727) 1 NC_007946.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 563727 purE 3991313 purE Escherichia coli UTI89 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_539583.1 563191 R 364106 CDS YP_539584.1 91209598 3991314 complement(563796..564125) 1 NC_007946.1 hypothetical protein 564125 3991314 UTI89_C0552 Escherichia coli UTI89 hypothetical protein YP_539584.1 563796 R 364106 CDS YP_539585.1 91209599 3991315 complement(564236..564958) 1 NC_007946.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 564958 ybbF 3991315 ybbF Escherichia coli UTI89 UDP-2,3-diacylglucosamine hydrolase YP_539585.1 564236 R 364106 CDS YP_539586.1 91209600 3991316 complement(564961..565455) 1 NC_007946.1 peptidyl-prolyl cis-trans isomerase B 565455 ppiB 3991316 ppiB Escherichia coli UTI89 peptidyl-prolyl cis-trans isomerase B YP_539586.1 564961 R 364106 CDS YP_539587.1 91209601 3991317 565629..567014 1 NC_007946.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 567014 cysS 3991317 cysS Escherichia coli UTI89 cysteinyl-tRNA synthetase YP_539587.1 565629 D 364106 CDS YP_539588.1 91209602 3993756 complement(567050..567571) 1 NC_007946.1 hypothetical protein 567571 ybcI 3993756 ybcI Escherichia coli UTI89 hypothetical protein YP_539588.1 567050 R 364106 CDS YP_539589.1 91209603 3993757 567657..567914 1 NC_007946.1 hypothetical protein 567914 3993757 UTI89_C0557 Escherichia coli UTI89 hypothetical protein YP_539589.1 567657 D 364106 CDS YP_539590.2 162138475 3993758 complement(567679..567891) 1 NC_007946.1 hypothetical protein 567891 ybcJ 3993758 ybcJ Escherichia coli UTI89 hypothetical protein YP_539590.2 567679 R 364106 CDS YP_539591.1 91209605 3993759 complement(567893..568759) 1 NC_007946.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 568759 folD 3993759 folD Escherichia coli UTI89 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_539591.1 567893 R 364106 CDS YP_539592.1 91209606 3993760 568809..568997 1 NC_007946.1 hypothetical protein 568997 3993760 UTI89_C0560 Escherichia coli UTI89 hypothetical protein YP_539592.1 568809 D 364106 CDS YP_539593.1 91209607 3993762 complement(569114..569467) 1 NC_007946.1 prophage DLP12 integrase 569467 intD 3993762 intD Escherichia coli UTI89 prophage DLP12 integrase YP_539593.1 569114 R 364106 CDS YP_539594.1 91209608 3993763 complement(569442..569834) 1 NC_007946.1 prophage DLP12 integrase 569834 3993763 UTI89_C0563 Escherichia coli UTI89 prophage DLP12 integrase YP_539594.1 569442 R 364106 CDS YP_539595.1 91209609 3993764 569748..570104 1 NC_007946.1 lambdoid prophage Qin tail fiber assembly protein-like protein 570104 tfaQ 3993764 tfaQ Escherichia coli UTI89 lambdoid prophage Qin tail fiber assembly protein-like protein YP_539595.1 569748 D 364106 CDS YP_539596.1 91209610 3993765 complement(570159..570824) 1 NC_007946.1 hypothetical protein 570824 3993765 UTI89_C0565 Escherichia coli UTI89 hypothetical protein YP_539596.1 570159 R 364106 CDS YP_539597.1 91209611 3993766 complement(571059..572012) 1 NC_007946.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 572012 ompT 3993766 ompT Escherichia coli UTI89 outer membrane protease YP_539597.1 571059 R 364106 CDS YP_539598.1 91209612 3993767 complement(572670..573560) 1 NC_007946.1 hypothetical protein 573560 ybcH 3993767 ybcH Escherichia coli UTI89 hypothetical protein YP_539598.1 572670 R 364106 CDS YP_539599.1 91209613 3993768 complement(573561..576554) 1 NC_007946.1 bacteriophage N4 receptor, outer membrane subunit 576554 nfrA 3993768 nfrA Escherichia coli UTI89 bacteriophage N4 receptor, outer membrane subunit YP_539599.1 573561 R 364106 CDS YP_539600.1 91209614 3993769 complement(576520..578757) 1 NC_007946.1 bacteriophage N4 adsorption protein B 578757 nfrB 3993769 nfrB Escherichia coli UTI89 bacteriophage N4 adsorption protein B YP_539600.1 576520 R 364106 CDS YP_539601.1 91209615 3993770 complement(578907..580349) 1 NC_007946.1 sensor kinase CusS 580349 cusS 3993770 cusS Escherichia coli UTI89 sensor kinase CusS YP_539601.1 578907 R 364106 CDS YP_539602.1 91209616 3993771 complement(580339..581022) 1 NC_007946.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 581022 ylcA 3993771 ylcA Escherichia coli UTI89 DNA-binding transcriptional activator CusR YP_539602.1 580339 R 364106 CDS YP_539603.1 91209617 3993772 581179..582561 1 NC_007946.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 582561 cusC 3993772 cusC Escherichia coli UTI89 copper/silver efflux system outer membrane protein CusC YP_539603.1 581179 D 364106 CDS YP_539604.1 91209618 3993773 582585..582917 1 NC_007946.1 periplasmic copper-binding protein 582917 ylcC 3993773 ylcC Escherichia coli UTI89 periplasmic copper-binding protein YP_539604.1 582585 D 364106 CDS YP_539605.1 91209619 3993774 582933..584156 1 NC_007946.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 584156 3993774 UTI89_C0574 Escherichia coli UTI89 copper/silver efflux system membrane fusion protein CusB YP_539605.1 582933 D 364106 CDS YP_539606.1 91209620 3992677 584168..587311 1 NC_007946.1 cation efflux system protein CusA 587311 cusA 3992677 cusA Escherichia coli UTI89 cation efflux system protein CusA YP_539606.1 584168 D 364106 CDS YP_539607.1 91209621 3992678 587377..588789 1 NC_007946.1 phenylalanine transporter 588789 pheP 3992678 pheP Escherichia coli UTI89 phenylalanine transporter YP_539607.1 587377 D 364106 CDS YP_539608.1 91209622 3992679 complement(588871..590118) 1 NC_007946.1 hypothetical protein 590118 ybdG 3992679 ybdG Escherichia coli UTI89 hypothetical protein YP_539608.1 588871 R 364106 CDS YP_539609.1 91209623 3992680 complement(590226..590879) 1 NC_007946.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 590879 nfnB 3992680 nfnB Escherichia coli UTI89 dihydropteridine reductase YP_539609.1 590226 R 364106 CDS YP_539610.1 91209624 3992681 complement(590958..591341) 1 NC_007946.1 hypothetical protein 591341 ybdF 3992681 ybdF Escherichia coli UTI89 hypothetical protein YP_539610.1 590958 R 364106 CDS YP_539611.1 91209625 3992682 complement(591406..591654) 1 NC_007946.1 hypothetical protein 591654 ybdJ 3992682 ybdJ Escherichia coli UTI89 hypothetical protein YP_539611.1 591406 R 364106 CDS YP_539612.1 91209626 3992683 complement(591720..592838) 1 NC_007946.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 592838 ybdK 3992683 ybdK Escherichia coli UTI89 carboxylate-amine ligase YP_539612.1 591720 R 364106 CDS YP_539613.1 91209627 3992684 complement(593054..593323) 1 NC_007946.1 hypothetical protein 593323 3992684 UTI89_C0582 Escherichia coli UTI89 hypothetical protein YP_539613.1 593054 R 364106 CDS YP_539614.1 91209628 3992685 complement(593566..594336) 1 NC_007946.1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 594336 entD 3992685 entD Escherichia coli UTI89 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_539614.1 593566 R 364106 CDS YP_539615.1 91209629 3992686 complement(594361..596601) 1 NC_007946.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 596601 fepA 3992686 fepA Escherichia coli UTI89 outer membrane receptor FepA YP_539615.1 594361 R 364106 CDS YP_539616.1 91209630 3992687 596594..596725 1 NC_007946.1 hypothetical protein 596725 3992687 UTI89_C0585 Escherichia coli UTI89 hypothetical protein YP_539616.1 596594 D 364106 CDS YP_539617.1 91209631 3992688 596844..598046 1 NC_007946.1 enterobactin/ferric enterobactin esterase 598046 fes 3992688 fes Escherichia coli UTI89 enterobactin/ferric enterobactin esterase YP_539617.1 596844 D 364106 CDS YP_539618.1 91209632 3992689 598043..598267 1 NC_007946.1 hypothetical protein 598267 3992689 UTI89_C0587 Escherichia coli UTI89 hypothetical protein YP_539618.1 598043 D 364106 CDS YP_539619.1 91209633 3992690 598264..602145 1 NC_007946.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 602145 entF 3992690 entF Escherichia coli UTI89 enterobactin synthase subunit F YP_539619.1 598264 D 364106 CDS YP_539620.1 91209634 3992691 602361..603494 1 NC_007946.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 603494 fepE 3992691 fepE Escherichia coli UTI89 ferric enterobactin transport protein FepE YP_539620.1 602361 D 364106 CDS YP_539621.1 91209635 3992692 complement(603491..604306) 1 NC_007946.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 604306 fepC 3992692 fepC Escherichia coli UTI89 iron-enterobactin transporter ATP-binding protein YP_539621.1 603491 R 364106 CDS YP_539622.1 91209636 3992693 complement(604303..605295) 1 NC_007946.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 605295 fepG 3992693 fepG Escherichia coli UTI89 iron-enterobactin transporter permease YP_539622.1 604303 R 364106 CDS YP_539623.1 91209637 3992694 complement(605292..606308) 1 NC_007946.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 606308 fepD 3992694 fepD Escherichia coli UTI89 iron-enterobactin transporter membrane protein YP_539623.1 605292 R 364106 CDS YP_539624.1 91209638 3992695 606407..607657 1 NC_007946.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 607657 ybdA 3992695 ybdA Escherichia coli UTI89 enterobactin exporter EntS YP_539624.1 606407 D 364106 CDS YP_539625.1 91209639 3993178 complement(607661..608617) 1 NC_007946.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 608617 fepB 3993178 fepB Escherichia coli UTI89 iron-enterobactin transporter periplasmic binding protein YP_539625.1 607661 R 364106 CDS YP_539626.1 91209640 3993179 608794..609981 1 NC_007946.1 isochorismate synthase 609981 entC 3993179 entC Escherichia coli UTI89 isochorismate synthase YP_539626.1 608794 D 364106 CDS YP_539627.1 91209641 3993180 609991..611601 1 NC_007946.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 611601 entE 3993180 entE Escherichia coli UTI89 enterobactin synthase subunit E YP_539627.1 609991 D 364106 CDS YP_539628.1 91209642 3993181 611615..612472 1 NC_007946.1 2,3-dihydro-2,3-dihydroxybenzoate synthetase 612472 entB 3993181 entB Escherichia coli UTI89 2,3-dihydro-2,3-dihydroxybenzoate synthetase YP_539628.1 611615 D 364106 CDS YP_539629.1 91209643 3993182 612472..613218 1 NC_007946.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 613218 entA 3993182 entA Escherichia coli UTI89 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_539629.1 612472 D 364106 CDS YP_539630.1 91209644 3993183 613221..613634 1 NC_007946.1 hypothetical protein 613634 ybdB 3993183 ybdB Escherichia coli UTI89 hypothetical protein YP_539630.1 613221 D 364106 CDS YP_539631.1 91209645 3993184 613815..615920 1 NC_007946.1 carbon starvation protein A 615920 cstA 3993184 cstA Escherichia coli UTI89 carbon starvation protein A YP_539631.1 613815 D 364106 CDS YP_539632.1 91209646 3993185 616033..616230 1 NC_007946.1 hypothetical protein 616230 ybdD 3993185 ybdD Escherichia coli UTI89 hypothetical protein YP_539632.1 616033 D 364106 CDS YP_539633.1 91209647 3993186 complement(616240..617328) 1 NC_007946.1 member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein 617328 ybdH 3993186 ybdH Escherichia coli UTI89 hypothetical protein YP_539633.1 616240 R 364106 CDS YP_539634.1 91209648 3993187 617448..618608 1 NC_007946.1 catalyzes the transfer of an amino moiety; aminotransferase 618608 ybdL 3993187 ybdL Escherichia coli UTI89 aminotransferase YP_539634.1 617448 D 364106 CDS YP_539635.1 91209649 3993188 complement(618609..619238) 1 NC_007946.1 hypothetical protein 619238 ybdM 3993188 ybdM Escherichia coli UTI89 hypothetical protein YP_539635.1 618609 R 364106 CDS YP_539636.1 91209650 3993189 complement(619211..620431) 1 NC_007946.1 hypothetical protein 620431 ybdN 3993189 ybdN Escherichia coli UTI89 hypothetical protein YP_539636.1 619211 R 364106 CDS YP_539637.1 91209651 3993190 complement(620578..621516) 1 NC_007946.1 transcriptional regulator YbdO 621516 ybdO 3993190 ybdO Escherichia coli UTI89 transcriptional regulator YbdO YP_539637.1 620578 R 364106 CDS YP_539638.2 162138474 3993191 complement(621685..622431) 1 NC_007946.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 622431 dsbG 3993191 dsbG Escherichia coli UTI89 disulfide isomerase/thiol-disulfide oxidase YP_539638.2 621685 R 364106 CDS YP_539639.1 91209653 3993192 622803..623366 1 NC_007946.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 623366 ahpC 3993192 ahpC Escherichia coli UTI89 alkyl hydroperoxide reductase YP_539639.1 622803 D 364106 CDS YP_539640.1 91209654 3993193 623507..625102 1 NC_007946.1 alkyl hydroperoxide reductase 625102 ahpF 3993193 ahpF Escherichia coli UTI89 alkyl hydroperoxide reductase YP_539640.1 623507 D 364106 CDS YP_539641.1 91209655 3993194 complement(625223..625684) 1 NC_007946.1 universal stress protein UspG 625684 uspG 3993194 uspG Escherichia coli UTI89 universal stress protein UspG YP_539641.1 625223 R 364106 CDS YP_539642.1 91209656 3993195 625935..626318 1 NC_007946.1 hypothetical protein 626318 3993195 UTI89_C0611 Escherichia coli UTI89 hypothetical protein YP_539642.1 625935 D 364106 CDS YP_539643.1 91209657 3993196 complement(626007..626417) 1 NC_007946.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 626417 rnk 3993196 rnk Escherichia coli UTI89 nucleoside diphosphate kinase regulator YP_539643.1 626007 R 364106 CDS YP_539644.1 91209658 3993197 complement(626647..627471) 1 NC_007946.1 ribonuclease I 627471 rna 3993197 rna Escherichia coli UTI89 ribonuclease I YP_539644.1 626647 R 364106 CDS YP_539645.1 91209659 3990938 complement(627567..629030) 1 NC_007946.1 citrate DASS carrier/transporter 629030 citT 3990938 citT Escherichia coli UTI89 citrate DASS carrier/transporter YP_539645.1 627567 R 364106 CDS YP_539646.1 91209660 3990939 complement(629081..629959) 1 NC_007946.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 629959 citG 3990939 citG Escherichia coli UTI89 triphosphoribosyl-dephospho-CoA synthase YP_539646.1 629081 R 364106 CDS YP_539647.1 91209661 3990940 complement(629934..630485) 1 NC_007946.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase 630485 citX 3990940 citX Escherichia coli UTI89 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase YP_539647.1 629934 R 364106 CDS YP_539648.1 91209662 3990941 630453..631847 1 NC_007946.1 hypothetical protein 631847 3990941 UTI89_C0617 Escherichia coli UTI89 hypothetical protein YP_539648.1 630453 D 364106 CDS YP_539649.1 91209663 3990942 complement(630489..632021) 1 NC_007946.1 citrate lyase subunit alpha 632021 citF 3990942 citF Escherichia coli UTI89 citrate lyase subunit alpha YP_539649.1 630489 R 364106 CDS YP_539650.1 91209664 3990943 632023..633069 1 NC_007946.1 hypothetical protein 633069 3990943 UTI89_C0619 Escherichia coli UTI89 hypothetical protein YP_539650.1 632023 D 364106 CDS YP_539651.1 91209665 3990944 complement(632032..632955) 1 NC_007946.1 citrate lyase subunit beta 632955 citE 3990944 citE Escherichia coli UTI89 citrate lyase subunit beta YP_539651.1 632032 R 364106 CDS YP_539652.1 91209666 3990945 complement(632937..633233) 1 NC_007946.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 633233 citD 3990945 citD Escherichia coli UTI89 citrate lyase subunit gamma YP_539652.1 632937 R 364106 CDS YP_539653.1 91209667 3990946 complement(633248..634393) 1 NC_007946.1 citrate lyase synthetase 634393 citC 3990946 citC Escherichia coli UTI89 citrate lyase synthetase YP_539653.1 633248 R 364106 CDS YP_539654.1 91209668 3990947 634625..636343 1 NC_007946.1 sensor kinase DpiB 636343 dpiB 3990947 dpiB Escherichia coli UTI89 sensor kinase DpiB YP_539654.1 634625 D 364106 CDS YP_539655.1 91209669 3990948 636312..636992 1 NC_007946.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 636992 dpiA 3990948 dpiA Escherichia coli UTI89 two-component response regulator DpiA YP_539655.1 636312 D 364106 CDS YP_539656.1 91209670 3990949 complement(637033..638418) 1 NC_007946.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 638418 dcuC 3990949 dcuC Escherichia coli UTI89 C4-dicarboxylate transporter DcuC YP_539656.1 637033 R 364106 CDS YP_539657.1 91209671 3990950 639005..639565 1 NC_007946.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 639565 pagP 3990950 pagP Escherichia coli UTI89 palmitoyl transferase YP_539657.1 639005 D 364106 CDS YP_539658.1 91209672 3990951 639656..639949 1 NC_007946.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 639949 cspE 3990951 cspE Escherichia coli UTI89 cold shock protein CspE YP_539658.1 639656 D 364106 CDS YP_539659.1 91209673 3990952 complement(640003..640386) 1 NC_007946.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 640386 crcB 3990952 crcB Escherichia coli UTI89 camphor resistance protein CrcB YP_539659.1 640003 R 364106 CDS YP_539660.1 91209674 3990953 640476..641270 1 NC_007946.1 amidase 641270 ybeM 3990953 ybeM Escherichia coli UTI89 amidase YP_539660.1 640476 D 364106 CDS YP_539661.1 91209675 3990954 641399..641602 1 NC_007946.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 641602 tatE 3990954 tatE Escherichia coli UTI89 twin arginine translocase E YP_539661.1 641399 D 364106 CDS YP_539662.1 91209676 3990955 complement(641702..642667) 1 NC_007946.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 642667 lipA 3990955 lipA Escherichia coli UTI89 lipoyl synthase YP_539662.1 641702 R 364106 CDS YP_539663.1 91209677 3990956 complement(643487..644128) 1 NC_007946.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 644128 lipB 3990956 lipB Escherichia coli UTI89 lipoate-protein ligase B YP_539663.1 643487 R 364106 CDS YP_539664.1 91209678 3989723 complement(644229..644492) 1 NC_007946.1 hypothetical protein 644492 ybeD 3989723 ybeD Escherichia coli UTI89 hypothetical protein YP_539664.1 644229 R 364106 CDS YP_539665.1 91209679 3989724 complement(644602..645813) 1 NC_007946.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A 645813 dacA 3989724 dacA Escherichia coli UTI89 D-alanyl-D-alanine carboxypeptidase fraction A YP_539665.1 644602 R 364106 CDS YP_539666.1 91209680 3989725 complement(645953..647041) 1 NC_007946.1 rare lipoprotein A 647041 rlpA 3989725 rlpA Escherichia coli UTI89 rare lipoprotein A YP_539666.1 645953 R 364106 CDS YP_539667.1 91209681 3989726 complement(647052..648164) 1 NC_007946.1 cell wall shape-determining protein 648164 mrdB 3989726 mrdB Escherichia coli UTI89 cell wall shape-determining protein YP_539667.1 647052 R 364106 CDS YP_539668.1 91209682 3989727 complement(648167..650068) 1 NC_007946.1 penicillin-binding protein 2 650068 mrdA 3989727 mrdA Escherichia coli UTI89 penicillin-binding protein 2 YP_539668.1 648167 R 364106 CDS YP_539669.1 91209683 3989728 complement(650099..650566) 1 NC_007946.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 650566 ybeA 3989728 ybeA Escherichia coli UTI89 rRNA large subunit methyltransferase YP_539669.1 650099 R 364106 CDS YP_539670.1 91209684 3989729 complement(650570..650887) 1 NC_007946.1 hypothetical protein 650887 ybeB 3989729 ybeB Escherichia coli UTI89 hypothetical protein YP_539670.1 650570 R 364106 CDS YP_539671.1 91209685 3989730 650901..651191 1 NC_007946.1 hypothetical protein 651191 3989730 UTI89_C0640 Escherichia coli UTI89 hypothetical protein YP_539671.1 650901 D 364106 CDS YP_539672.1 91209686 3989731 complement(651147..651761) 1 NC_007946.1 alpha-ribazole-5'-phosphate phosphatase 651761 phpB 3989731 phpB Escherichia coli UTI89 alpha-ribazole-5'-phosphate phosphatase YP_539672.1 651147 R 364106 CDS YP_539673.1 91209687 3989732 complement(651782..652486) 1 NC_007946.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 652486 nadD 3989732 nadD Escherichia coli UTI89 nicotinic acid mononucleotide adenylyltransferase YP_539673.1 651782 R 364106 CDS YP_539674.1 91209688 3989733 complement(652425..653456) 1 NC_007946.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 653456 holA 3989733 holA Escherichia coli UTI89 DNA polymerase III subunit delta YP_539674.1 652425 R 364106 CDS YP_539675.1 91209689 3989734 complement(653456..654037) 1 NC_007946.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 654037 rlpB 3989734 rlpB Escherichia coli UTI89 LPS-assembly lipoprotein RlpB YP_539675.1 653456 R 364106 CDS YP_539676.1 91209690 3989735 complement(654052..656775) 1 NC_007946.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 656775 leuS 3989735 leuS Escherichia coli UTI89 leucyl-tRNA synthetase YP_539676.1 654052 R 364106 CDS YP_539677.1 91209691 3989736 656869..657351 1 NC_007946.1 hypothetical protein 657351 ybeL 3989736 ybeL Escherichia coli UTI89 hypothetical protein YP_539677.1 656869 D 364106 CDS YP_539678.2 162138473 3989737 complement(657396..658331) 1 NC_007946.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 658331 rihA 3989737 rihA Escherichia coli UTI89 ribonucleoside hydrolase 1 YP_539678.2 657396 R 364106 CDS YP_539679.1 91209693 3989738 complement(658449..659174) 1 NC_007946.1 ATP-binding protein of glutamate/aspartate transport system 659174 gltL 3989738 gltL Escherichia coli UTI89 ATP-binding protein of glutamate/aspartate transport system YP_539679.1 658449 R 364106 CDS YP_539680.1 91209694 3989739 complement(659174..659848) 1 NC_007946.1 glutamate/aspartate transport system permease 659848 gltK 3989739 gltK Escherichia coli UTI89 glutamate/aspartate transport system permease YP_539680.1 659174 R 364106 CDS YP_539681.1 91209695 3989740 complement(659848..660588) 1 NC_007946.1 glutamate ABC transporter 660588 gltJ 3989740 gltJ Escherichia coli UTI89 glutamate ABC transporter YP_539681.1 659848 R 364106 CDS YP_539682.1 91209696 3989741 complement(660758..661735) 1 NC_007946.1 glutamate and aspartate transporter subunit 661735 ybeJ 3989741 ybeJ Escherichia coli UTI89 glutamate and aspartate transporter subunit YP_539682.1 660758 R 364106 CDS YP_539683.1 91209697 3989742 661801..661923 1 NC_007946.1 hypothetical protein 661923 3989742 UTI89_C0652 Escherichia coli UTI89 hypothetical protein YP_539683.1 661801 D 364106 CDS YP_539684.1 91209698 3991388 662120..663997 1 NC_007946.1 hypothetical protein 663997 3991388 UTI89_C0653 Escherichia coli UTI89 hypothetical protein YP_539684.1 662120 D 364106 CDS YP_539685.1 91209699 3991389 663966..664142 1 NC_007946.1 hypothetical protein 664142 3991389 UTI89_C0654 Escherichia coli UTI89 hypothetical protein YP_539685.1 663966 D 364106 CDS YP_539686.1 91209700 3991390 complement(664124..665665) 1 NC_007946.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 665665 lnt 3991390 lnt Escherichia coli UTI89 apolipoprotein N-acyltransferase YP_539686.1 664124 R 364106 CDS YP_539687.1 91209701 3991391 complement(665690..666568) 1 NC_007946.1 transport protein 666568 ybeX 3991391 ybeX Escherichia coli UTI89 transport protein YP_539687.1 665690 R 364106 CDS YP_539688.1 91209702 3991392 complement(666658..667125) 1 NC_007946.1 metalloprotease 667125 ybeY 3991392 ybeY Escherichia coli UTI89 metalloprotease YP_539688.1 666658 R 364106 CDS YP_539689.1 91209703 3991393 complement(667122..668201) 1 NC_007946.1 ATP-binding protein in pho regulon 668201 ybeZ 3991393 ybeZ Escherichia coli UTI89 ATP-binding protein in pho regulon YP_539689.1 667122 R 364106 CDS YP_539690.1 91209704 3991394 complement(668315..669739) 1 NC_007946.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 669739 3991394 UTI89_C0659 Escherichia coli UTI89 (dimethylallyl)adenosine tRNA methylthiotransferase YP_539690.1 668315 R 364106 CDS YP_539691.1 91209705 3991395 669885..671060 1 NC_007946.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 671060 ubiF 3991395 ubiF Escherichia coli UTI89 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_539691.1 669885 D 364106 CDS YP_539692.1 91209706 3990331 complement(672301..674199) 1 NC_007946.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 674199 asnB 3990331 asnB Escherichia coli UTI89 asparagine synthetase B YP_539692.1 672301 R 364106 CDS YP_539693.1 91209707 3990332 complement(674221..674973) 1 NC_007946.1 UMP phosphatase 674973 nagD 3990332 nagD Escherichia coli UTI89 UMP phosphatase YP_539693.1 674221 R 364106 CDS YP_539694.1 91209708 3990333 complement(675021..676241) 1 NC_007946.1 N-acetylglucosamine operon transcriptional repressor 676241 nagC 3990333 nagC Escherichia coli UTI89 N-acetylglucosamine operon transcriptional repressor YP_539694.1 675021 R 364106 CDS YP_539695.1 91209709 3990334 complement(676250..677398) 1 NC_007946.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 677398 nagA 3990334 nagA Escherichia coli UTI89 N-acetylglucosamine-6-phosphate deacetylase YP_539695.1 676250 R 364106 CDS YP_539696.1 91209710 3990335 complement(677458..678258) 1 NC_007946.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 678258 nagB 3990335 nagB Escherichia coli UTI89 glucosamine-6-phosphate deaminase YP_539696.1 677458 R 364106 CDS YP_539697.1 91209711 3990336 complement(678307..678441) 1 NC_007946.1 hypothetical protein 678441 3990336 UTI89_C0673 Escherichia coli UTI89 hypothetical protein YP_539697.1 678307 R 364106 CDS YP_539698.1 91209712 3990337 678591..680537 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 680537 nagE 3990337 nagE Escherichia coli UTI89 PTS system N-acetyl glucosamine specific transporter subunits IIABC YP_539698.1 678591 D 364106 CDS YP_539699.1 91209713 3990338 complement(680507..680659) 1 NC_007946.1 hypothetical protein 680659 3990338 UTI89_C0675 Escherichia coli UTI89 hypothetical protein YP_539699.1 680507 R 364106 CDS YP_539700.1 91209714 3990339 complement(680626..681906) 1 NC_007946.1 hypothetical protein 681906 3990339 UTI89_C0676 Escherichia coli UTI89 hypothetical protein YP_539700.1 680626 R 364106 CDS YP_539701.1 91209715 3990340 complement(681920..682390) 1 NC_007946.1 hypothetical protein 682390 3990340 UTI89_C0677 Escherichia coli UTI89 hypothetical protein YP_539701.1 681920 R 364106 CDS YP_539702.1 91209716 3990341 complement(682387..683556) 1 NC_007946.1 hypothetical protein 683556 3990341 UTI89_C0678 Escherichia coli UTI89 hypothetical protein YP_539702.1 682387 R 364106 CDS YP_539703.1 91209717 3990342 complement(684402..685289) 1 NC_007946.1 dihydrodipicolinate synthase 685289 3990342 UTI89_C0679 Escherichia coli UTI89 dihydrodipicolinate synthase YP_539703.1 684402 R 364106 CDS YP_539704.1 91209718 3990343 complement(685293..686450) 1 NC_007946.1 alcohol dehydrogenase 686450 3990343 UTI89_C0680 Escherichia coli UTI89 alcohol dehydrogenase YP_539704.1 685293 R 364106 CDS YP_539705.1 91209719 3990344 686725..687855 1 NC_007946.1 hypothetical protein 687855 3990344 UTI89_C0681 Escherichia coli UTI89 hypothetical protein YP_539705.1 686725 D 364106 CDS YP_539706.1 91209720 3990345 687848..688834 1 NC_007946.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 688834 pdxA 3990345 pdxA Escherichia coli UTI89 4-hydroxythreonine-4-phosphate dehydrogenase YP_539706.1 687848 D 364106 CDS YP_539707.1 91209721 3990346 688836..689597 1 NC_007946.1 transcriptional regulator 689597 3990346 UTI89_C0683 Escherichia coli UTI89 transcriptional regulator YP_539707.1 688836 D 364106 CDS YP_539708.1 91209722 3994292 689817..691481 1 NC_007946.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 691481 glnS 3994292 glnS Escherichia coli UTI89 glutaminyl-tRNA synthetase YP_539708.1 689817 D 364106 CDS YP_539709.1 91209723 3994293 691930..693336 1 NC_007946.1 hypothetical protein 693336 ybfM 3994293 ybfM Escherichia coli UTI89 hypothetical protein YP_539709.1 691930 D 364106 CDS YP_539710.1 91209724 3994294 693386..693712 1 NC_007946.1 lipoprotein YbfN 693712 ybfN 3994294 ybfN Escherichia coli UTI89 lipoprotein YbfN YP_539710.1 693386 D 364106 CDS YP_539711.1 91209725 3994295 complement(693796..694242) 1 NC_007946.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 694242 fur 3994295 fur Escherichia coli UTI89 ferric uptake regulator YP_539711.1 693796 R 364106 CDS YP_539712.1 91209726 3994296 694287..694541 1 NC_007946.1 hypothetical protein 694541 ybfJ 3994296 ybfJ Escherichia coli UTI89 hypothetical protein YP_539712.1 694287 D 364106 CDS YP_539713.1 91209727 3994297 complement(694531..695178) 1 NC_007946.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 695178 fldA 3994297 fldA Escherichia coli UTI89 flavodoxin FldA YP_539713.1 694531 R 364106 CDS YP_539714.1 91209728 3994298 complement(695201..695563) 1 NC_007946.1 LexA regulated protein 695563 ybfE 3994298 ybfE Escherichia coli UTI89 LexA regulated protein YP_539714.1 695201 R 364106 CDS YP_539715.1 91209729 3994299 complement(695634..696398) 1 NC_007946.1 hypothetical protein 696398 ybfF 3994299 ybfF Escherichia coli UTI89 hypothetical protein YP_539715.1 695634 R 364106 CDS YP_539716.2 162138472 3994300 696583..697128 1 NC_007946.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 697128 seqA 3994300 seqA Escherichia coli UTI89 replication initiation regulator SeqA YP_539716.2 696583 D 364106 CDS YP_539717.1 91209731 3994301 697103..698794 1 NC_007946.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 698794 pgm 3994301 pgm Escherichia coli UTI89 phosphoglucomutase YP_539717.1 697103 D 364106 CDS YP_539718.1 91209732 3994302 complement(698851..700170) 1 NC_007946.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 700170 potE 3994302 potE Escherichia coli UTI89 putrescine transporter YP_539718.1 698851 R 364106 CDS YP_539719.1 91209733 3994303 complement(700167..702374) 1 NC_007946.1 ornithine decarboxylase 702374 speF 3994303 speF Escherichia coli UTI89 ornithine decarboxylase YP_539719.1 700167 R 364106 CDS YP_539720.1 91209734 3994304 complement(702379..702531) 1 NC_007946.1 hypothetical protein 702531 3994304 UTI89_C0696 Escherichia coli UTI89 hypothetical protein YP_539720.1 702379 R 364106 CDS YP_539721.1 91209735 3994305 702898..703032 1 NC_007946.1 hypothetical protein 703032 3994305 UTI89_C0697 Escherichia coli UTI89 hypothetical protein YP_539721.1 702898 D 364106 CDS YP_539722.1 91209736 3994306 complement(703054..703731) 1 NC_007946.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 703731 kdpE 3994306 kdpE Escherichia coli UTI89 DNA-binding transcriptional activator KdpE YP_539722.1 703054 R 364106 CDS YP_539723.1 91209737 3994307 complement(703728..706415) 1 NC_007946.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 706415 kdpD 3994307 kdpD Escherichia coli UTI89 sensor protein KdpD YP_539723.1 703728 R 364106 CDS YP_539724.1 91209738 3994308 complement(706405..707001) 1 NC_007946.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 707001 kdpC 3994308 kdpC Escherichia coli UTI89 potassium-transporting ATPase subunit C YP_539724.1 706405 R 364106 CDS YP_539725.1 91209739 3994309 complement(706986..709034) 1 NC_007946.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 709034 kdpB 3994309 kdpB Escherichia coli UTI89 potassium-transporting ATPase subunit B YP_539725.1 706986 R 364106 CDS YP_539726.1 91209740 3994310 complement(709057..710730) 1 NC_007946.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 710730 kdpA 3994310 kdpA Escherichia coli UTI89 potassium-transporting ATPase subunit A YP_539726.1 709057 R 364106 CDS YP_539727.1 91209741 3994311 complement(710730..710933) 1 NC_007946.1 hypothetical protein 710933 3994311 UTI89_C0703 Escherichia coli UTI89 hypothetical protein YP_539727.1 710730 R 364106 CDS YP_539728.1 91209742 3993966 711132..711338 1 NC_007946.1 hypothetical protein 711338 ybfA 3993966 ybfA Escherichia coli UTI89 hypothetical protein YP_539728.1 711132 D 364106 CDS YP_539729.1 91209743 3993967 711439..711948 1 NC_007946.1 hypothetical protein 711948 ybgA 3993967 ybgA Escherichia coli UTI89 hypothetical protein YP_539729.1 711439 D 364106 CDS YP_539730.1 91209744 3993968 711945..713363 1 NC_007946.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 713363 phrB 3993968 phrB Escherichia coli UTI89 deoxyribodipyrimidine photolyase YP_539730.1 711945 D 364106 CDS YP_539731.1 91209745 3993969 complement(713405..714886) 1 NC_007946.1 transporter YbgH 714886 ybgH 3993969 ybgH Escherichia coli UTI89 transporter YbgH YP_539731.1 713405 R 364106 CDS YP_539732.1 91209746 3993970 715157..715900 1 NC_007946.1 hydrolase-oxidase 715900 ybgI 3993970 ybgI Escherichia coli UTI89 hydrolase-oxidase YP_539732.1 715157 D 364106 CDS YP_539733.1 91209747 3993971 715923..716579 1 NC_007946.1 hypothetical protein 716579 ybgJ 3993971 ybgJ Escherichia coli UTI89 hypothetical protein YP_539733.1 715923 D 364106 CDS YP_539734.1 91209748 3993972 716573..717505 1 NC_007946.1 hypothetical protein 717505 ybgK 3993972 ybgK Escherichia coli UTI89 hypothetical protein YP_539734.1 716573 D 364106 CDS YP_539735.1 91209749 3993973 717495..718229 1 NC_007946.1 LamB/YcsF family protein 718229 ybgL 3993973 ybgL Escherichia coli UTI89 LamB/YcsF family protein YP_539735.1 717495 D 364106 CDS YP_539736.1 91209750 3993974 718265..719056 1 NC_007946.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 719056 nei 3993974 nei Escherichia coli UTI89 endonuclease VIII YP_539736.1 718265 D 364106 CDS YP_539737.1 91209751 3993975 complement(719053..720144) 1 NC_007946.1 transport protein AbrB 720144 abrB 3993975 abrB Escherichia coli UTI89 transport protein AbrB YP_539737.1 719053 R 364106 CDS YP_539738.1 91209752 3993976 complement(720251..720625) 1 NC_007946.1 hypothetical protein 720625 ybgO 3993976 ybgO Escherichia coli UTI89 hypothetical protein YP_539738.1 720251 R 364106 CDS YP_539739.1 91209753 3993977 complement(720773..722056) 1 NC_007946.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 722056 gltA 3993977 gltA Escherichia coli UTI89 type II citrate synthase YP_539739.1 720773 R 364106 CDS YP_539740.1 91209754 3993978 722038..722229 1 NC_007946.1 hypothetical protein 722229 3993978 UTI89_C0716 Escherichia coli UTI89 hypothetical protein YP_539740.1 722038 D 364106 CDS YP_539741.1 91209755 3993979 722750..723154 1 NC_007946.1 succinate dehydrogenase cytochrome b556 large membrane subunit 723154 sdhC 3993979 sdhC Escherichia coli UTI89 succinate dehydrogenase cytochrome b556 large membrane subunit YP_539741.1 722750 D 364106 CDS YP_539742.1 91209756 3993980 723148..723495 1 NC_007946.1 succinate dehydrogenase cytochrome b556 small membrane subunit 723495 sdhD 3993980 sdhD Escherichia coli UTI89 succinate dehydrogenase cytochrome b556 small membrane subunit YP_539742.1 723148 D 364106 CDS YP_539743.1 91209757 3993981 723483..725261 1 NC_007946.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 725261 sdhA 3993981 sdhA Escherichia coli UTI89 succinate dehydrogenase flavoprotein subunit YP_539743.1 723483 D 364106 CDS YP_539744.1 91209758 3993982 725277..725993 1 NC_007946.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 725993 sdhB 3993982 sdhB Escherichia coli UTI89 succinate dehydrogenase iron-sulfur subunit YP_539744.1 725277 D 364106 CDS YP_539745.1 91209759 3993983 726354..729155 1 NC_007946.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 729155 sucA 3993983 sucA Escherichia coli UTI89 2-oxoglutarate dehydrogenase E1 YP_539745.1 726354 D 364106 CDS YP_539746.1 91209760 3993984 729170..730387 1 NC_007946.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 730387 sucB 3993984 sucB Escherichia coli UTI89 dihydrolipoamide succinyltransferase YP_539746.1 729170 D 364106 CDS YP_539747.1 91209761 3993463 730481..731647 1 NC_007946.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 731647 sucC 3993463 sucC Escherichia coli UTI89 succinyl-CoA synthetase subunit beta YP_539747.1 730481 D 364106 CDS YP_539748.1 91209762 3993464 731647..732516 1 NC_007946.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 732516 sucD 3993464 sucD Escherichia coli UTI89 succinyl-CoA synthetase subunit alpha YP_539748.1 731647 D 364106 CDS YP_539749.1 91209763 3993465 732756..733871 1 NC_007946.1 hypothetical protein 733871 3993465 UTI89_C0725 Escherichia coli UTI89 hypothetical protein YP_539749.1 732756 D 364106 CDS YP_539750.1 91209764 3993466 733753..734097 1 NC_007946.1 hypothetical protein 734097 3993466 UTI89_C0726 Escherichia coli UTI89 hypothetical protein YP_539750.1 733753 D 364106 CDS YP_539751.1 91209765 3993467 735198..736769 1 NC_007946.1 cytochrome d terminal oxidase, polypeptide subunit I 736769 cydA 3993467 cydA Escherichia coli UTI89 cytochrome d terminal oxidase, polypeptide subunit I YP_539751.1 735198 D 364106 CDS YP_539752.1 91209766 3993468 complement(736674..737954) 1 NC_007946.1 hypothetical protein 737954 3993468 UTI89_C0728 Escherichia coli UTI89 hypothetical protein YP_539752.1 736674 R 364106 CDS YP_539753.1 91209767 3993469 736785..737924 1 NC_007946.1 cytochrome d terminal oxidase polypeptide subunit II 737924 cydB 3993469 cydB Escherichia coli UTI89 cytochrome d terminal oxidase polypeptide subunit II YP_539753.1 736785 D 364106 CDS YP_539754.1 91209768 3993470 737939..738052 1 NC_007946.1 hypothetical protein 738052 3993470 UTI89_C0730 Escherichia coli UTI89 hypothetical protein YP_539754.1 737939 D 364106 CDS YP_539755.1 91209769 3993471 738052..738345 1 NC_007946.1 hypothetical protein 738345 ybgE 3993471 ybgE Escherichia coli UTI89 hypothetical protein YP_539755.1 738052 D 364106 CDS YP_539756.1 91209770 3993472 738495..738899 1 NC_007946.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 738899 ybgC 3993472 ybgC Escherichia coli UTI89 acyl-CoA thioester hydrolase YP_539756.1 738495 D 364106 CDS YP_539757.1 91209771 3993473 738896..739588 1 NC_007946.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 739588 tolQ 3993473 tolQ Escherichia coli UTI89 colicin uptake protein TolQ YP_539757.1 738896 D 364106 CDS YP_539758.1 91209772 3993474 739592..740020 1 NC_007946.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 740020 tolR 3993474 tolR Escherichia coli UTI89 colicin uptake protein TolR YP_539758.1 739592 D 364106 CDS YP_539759.1 91209773 3993475 740085..741335 1 NC_007946.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 741335 tolA 3993475 tolA Escherichia coli UTI89 cell envelope integrity inner membrane protein TolA YP_539759.1 740085 D 364106 CDS YP_539760.1 91209774 3993476 741465..742760 1 NC_007946.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 742760 tolB 3993476 tolB Escherichia coli UTI89 translocation protein TolB YP_539760.1 741465 D 364106 CDS YP_539761.1 91209775 3993477 complement(742729..743346) 1 NC_007946.1 hypothetical protein 743346 3993477 UTI89_C0737 Escherichia coli UTI89 hypothetical protein YP_539761.1 742729 R 364106 CDS YP_539762.1 91209776 3993478 742771..743316 1 NC_007946.1 peptidoglycan-associated outer membrane lipoprotein 743316 pal 3993478 pal Escherichia coli UTI89 peptidoglycan-associated outer membrane lipoprotein YP_539762.1 742771 D 364106 CDS YP_539763.1 91209777 3993479 743326..744117 1 NC_007946.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 744117 ybgF 3993479 ybgF Escherichia coli UTI89 tol-pal system protein YbgF YP_539763.1 743326 D 364106 CDS YP_539764.1 91209778 3991524 745263..746306 1 NC_007946.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 746306 nadA 3991524 nadA Escherichia coli UTI89 quinolinate synthetase YP_539764.1 745263 D 364106 CDS YP_539765.1 91209779 3991525 746344..747063 1 NC_007946.1 PnuC NMN transporter 747063 pnuC 3991525 pnuC Escherichia coli UTI89 PnuC NMN transporter YP_539765.1 746344 D 364106 CDS YP_539766.1 91209780 3991526 complement(747060..748001) 1 NC_007946.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 748001 3991526 UTI89_C0749 Escherichia coli UTI89 zinc transporter ZitB YP_539766.1 747060 R 364106 CDS YP_539767.1 91209781 3991527 complement(748115..748495) 1 NC_007946.1 homeobox protein 748495 3991527 UTI89_C0750 Escherichia coli UTI89 homeobox protein YP_539767.1 748115 R 364106 CDS YP_539768.1 91209782 3991528 748811..749863 1 NC_007946.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 749863 aroG 3991528 aroG Escherichia coli UTI89 phospho-2-dehydro-3-deoxyheptonate aldolase YP_539768.1 748811 D 364106 CDS YP_539769.1 91209783 3991529 complement(750030..750797) 1 NC_007946.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 750797 gpmA 3991529 gpmA Escherichia coli UTI89 phosphoglyceromutase YP_539769.1 750030 R 364106 CDS YP_539770.1 91209784 3991530 complement(750985..752025) 1 NC_007946.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 752025 galM 3991530 galM Escherichia coli UTI89 aldose 1-epimerase YP_539770.1 750985 R 364106 CDS YP_539771.1 91209785 3991531 complement(752019..753167) 1 NC_007946.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 753167 galK 3991531 galK Escherichia coli UTI89 galactokinase YP_539771.1 752019 R 364106 CDS YP_539772.1 91209786 3992873 complement(753171..754217) 1 NC_007946.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 754217 galT 3992873 galT Escherichia coli UTI89 galactose-1-phosphate uridylyltransferase YP_539772.1 753171 R 364106 CDS YP_539773.1 91209787 3992874 complement(754227..755243) 1 NC_007946.1 UDP-galactose-4-epimerase 755243 3992874 UTI89_C0756 Escherichia coli UTI89 UDP-galactose-4-epimerase YP_539773.1 754227 R 364106 CDS YP_539774.2 162138471 3992875 complement(755506..756978) 1 NC_007946.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 756978 modF 3992875 modF Escherichia coli UTI89 molybdenum transport ATP-binding protein ModF YP_539774.2 755506 R 364106 CDS YP_539775.1 91209789 3992876 complement(757046..757834) 1 NC_007946.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; ModE family transcriptional regulator 757834 modE 3992876 modE Escherichia coli UTI89 ModE family transcriptional regulator YP_539775.1 757046 R 364106 CDS YP_539776.1 91209790 3992877 757957..758112 1 NC_007946.1 hypothetical protein 758112 ybhT 3992877 ybhT Escherichia coli UTI89 hypothetical protein YP_539776.1 757957 D 364106 CDS YP_539777.1 91209791 3992878 758048..758257 1 NC_007946.1 hypothetical protein 758257 3992878 UTI89_C0760 Escherichia coli UTI89 hypothetical protein YP_539777.1 758048 D 364106 CDS YP_539778.1 91209792 3992879 758279..759052 1 NC_007946.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 759052 modA 3992879 modA Escherichia coli UTI89 molybdate transporter periplasmic protein YP_539778.1 758279 D 364106 CDS YP_539779.1 91209793 3992880 759052..759741 1 NC_007946.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 759741 modB 3992880 modB Escherichia coli UTI89 molybdate ABC transporter permease YP_539779.1 759052 D 364106 CDS YP_539780.1 91209794 3992881 759744..760802 1 NC_007946.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate ABC transporter ATP-binding protein 760802 modC 3992881 modC Escherichia coli UTI89 molybdate ABC transporter ATP-binding protein YP_539780.1 759744 D 364106 CDS YP_539781.1 91209795 3992882 complement(760803..761621) 1 NC_007946.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 761621 ybhA 3992882 ybhA Escherichia coli UTI89 phosphotransferase YP_539781.1 760803 R 364106 CDS YP_539782.1 91209796 3992883 761776..762771 1 NC_007946.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 762771 ybhE 3992883 ybhE Escherichia coli UTI89 6-phosphogluconolactonase YP_539782.1 761776 D 364106 CDS YP_539783.1 91209797 3992884 complement(762812..763828) 1 NC_007946.1 transcriptional regulator YbhD 763828 ybhD 3992884 ybhD Escherichia coli UTI89 transcriptional regulator YbhD YP_539783.1 762812 R 364106 CDS YP_539784.1 91209798 3992885 763949..765001 1 NC_007946.1 hypothetical protein 765001 ybhH 3992885 ybhH Escherichia coli UTI89 hypothetical protein YP_539784.1 763949 D 364106 CDS YP_539785.1 91209799 3992886 765077..766510 1 NC_007946.1 hypothetical protein 766510 ybhI 3992886 ybhI Escherichia coli UTI89 hypothetical protein YP_539785.1 765077 D 364106 CDS YP_539786.2 162138470 3992887 766693..768954 1 NC_007946.1 hypothetical protein 768954 ybhJ 3992887 ybhJ Escherichia coli UTI89 hypothetical protein YP_539786.2 766693 D 364106 CDS YP_539787.1 91209801 3992888 complement(769095..770378) 1 NC_007946.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase 770378 ybhC 3992888 ybhC Escherichia coli UTI89 pectinesterase YP_539787.1 769095 R 364106 CDS YP_539788.1 91209802 3992889 complement(770530..771006) 1 NC_007946.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 771006 ybhB 3992889 ybhB Escherichia coli UTI89 kinase inhibitor protein YP_539788.1 770530 R 364106 CDS YP_539789.1 91209803 3992890 complement(771065..772465) 1 NC_007946.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 772465 bioA 3992890 bioA Escherichia coli UTI89 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_539789.1 771065 R 364106 CDS YP_539790.1 91209804 3992891 772441..773481 1 NC_007946.1 biotin synthase 773481 bioB 3992891 bioB Escherichia coli UTI89 biotin synthase YP_539790.1 772441 D 364106 CDS YP_539791.1 91209805 3993848 773478..774632 1 NC_007946.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 774632 bioF 3993848 bioF Escherichia coli UTI89 8-amino-7-oxononanoate synthase YP_539791.1 773478 D 364106 CDS YP_539792.1 91209806 3993849 774580..775374 1 NC_007946.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 775374 bioC 3993849 bioC Escherichia coli UTI89 biotin biosynthesis protein BioC YP_539792.1 774580 D 364106 CDS YP_539793.1 91209807 3993850 775367..776044 1 NC_007946.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 776044 bioD 3993850 bioD Escherichia coli UTI89 dithiobiotin synthetase YP_539793.1 775367 D 364106 CDS YP_539794.1 91209808 3993851 776623..778644 1 NC_007946.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 778644 uvrB 3993851 uvrB Escherichia coli UTI89 excinuclease ABC subunit B YP_539794.1 776623 D 364106 CDS YP_539795.1 91209809 3993852 complement(778682..779650) 1 NC_007946.1 hypothetical protein 779650 ybhK 3993852 ybhK Escherichia coli UTI89 hypothetical protein YP_539795.1 778682 R 364106 CDS YP_539796.1 91209810 3993853 complement(779833..779988) 1 NC_007946.1 hypothetical protein 779988 3993853 UTI89_C0779 Escherichia coli UTI89 hypothetical protein YP_539796.1 779833 R 364106 CDS YP_539797.1 91209811 3993854 779906..780976 1 NC_007946.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 780976 moaA 3993854 moaA Escherichia coli UTI89 molybdenum cofactor biosynthesis protein A YP_539797.1 779906 D 364106 CDS YP_539798.1 91209812 3993855 780998..781510 1 NC_007946.1 molybdopterin biosynthesis, protein B 781510 moaB 3993855 moaB Escherichia coli UTI89 molybdopterin biosynthesis, protein B YP_539798.1 780998 D 364106 CDS YP_539799.1 91209813 3993856 complement(781252..781743) 1 NC_007946.1 hypothetical protein 781743 3993856 UTI89_C0782 Escherichia coli UTI89 hypothetical protein YP_539799.1 781252 R 364106 CDS YP_539800.1 91209814 3993857 781513..781998 1 NC_007946.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 781998 moaC 3993857 moaC Escherichia coli UTI89 molybdenum cofactor biosynthesis protein MoaC YP_539800.1 781513 D 364106 CDS YP_539801.2 162138469 3993858 781991..782236 1 NC_007946.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 782236 moaD 3993858 moaD Escherichia coli UTI89 molybdopterin synthase small subunit YP_539801.2 781991 D 364106 CDS YP_539802.1 91209816 3993859 782238..782690 1 NC_007946.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 782690 moaE 3993859 moaE Escherichia coli UTI89 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_539802.1 782238 D 364106 CDS YP_539803.1 91209817 3993860 782827..783531 1 NC_007946.1 hypothetical protein 783531 ybhL 3993860 ybhL Escherichia coli UTI89 hypothetical protein YP_539803.1 782827 D 364106 CDS YP_539804.1 91209818 3993861 complement(783463..783594) 1 NC_007946.1 hypothetical protein 783594 3993861 UTI89_C0787 Escherichia coli UTI89 hypothetical protein YP_539804.1 783463 R 364106 CDS YP_539805.1 91209819 3993862 783710..784450 1 NC_007946.1 hypothetical protein 784450 ybhM 3993862 ybhM Escherichia coli UTI89 hypothetical protein YP_539805.1 783710 D 364106 CDS YP_539806.1 91209820 3993863 complement(784486..785442) 1 NC_007946.1 hypothetical protein 785442 ybhN 3993863 ybhN Escherichia coli UTI89 hypothetical protein YP_539806.1 784486 R 364106 CDS YP_539807.1 91209821 3993864 complement(785442..786683) 1 NC_007946.1 cardiolipin synthase 2 786683 ybhO 3993864 ybhO Escherichia coli UTI89 cardiolipin synthase 2 YP_539807.1 785442 R 364106 CDS YP_539808.1 91209822 3993865 complement(786680..787441) 1 NC_007946.1 DNase 787441 ybhP 3993865 ybhP Escherichia coli UTI89 DNase YP_539808.1 786680 R 364106 CDS YP_539809.1 91209823 3993866 787574..787984 1 NC_007946.1 hypothetical protein 787984 ybhQ 3993866 ybhQ Escherichia coli UTI89 hypothetical protein YP_539809.1 787574 D 364106 CDS YP_539810.1 91209824 3993867 complement(787946..789052) 1 NC_007946.1 hypothetical protein 789052 ybhR 3993867 ybhR Escherichia coli UTI89 hypothetical protein YP_539810.1 787946 R 364106 CDS YP_539811.1 91209825 3994481 complement(789063..790196) 1 NC_007946.1 hypothetical protein 790196 ybhS 3994481 ybhS Escherichia coli UTI89 hypothetical protein YP_539811.1 789063 R 364106 CDS YP_539812.1 91209826 3994482 complement(790189..791940) 1 NC_007946.1 ABC transporter 791940 ybhF 3994482 ybhF Escherichia coli UTI89 ABC transporter YP_539812.1 790189 R 364106 CDS YP_539813.1 91209827 3994483 complement(791918..792916) 1 NC_007946.1 hypothetical protein 792916 ybhG 3994483 ybhG Escherichia coli UTI89 hypothetical protein YP_539813.1 791918 R 364106 CDS YP_539814.1 91209828 3994484 complement(792916..793599) 1 NC_007946.1 DNA-binding transcriptional regulator 793599 ybiH 3994484 ybiH Escherichia coli UTI89 DNA-binding transcriptional regulator YP_539814.1 792916 R 364106 CDS YP_539815.1 91209829 3994485 793816..795177 1 NC_007946.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 795177 rhlE 3994485 rhlE Escherichia coli UTI89 ATP-dependent RNA helicase RhlE YP_539815.1 793816 D 364106 CDS YP_539818.1 91209832 3994488 complement(795410..795715) 1 NC_007946.1 hypothetical protein 795715 3994488 UTI89_C0801 Escherichia coli UTI89 hypothetical protein YP_539818.1 795410 R 364106 CDS YP_539819.1 91209833 3994489 795714..797864 1 NC_007946.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 797864 dinG 3994489 dinG Escherichia coli UTI89 ATP-dependent DNA helicase DinG YP_539819.1 795714 D 364106 CDS YP_539820.1 91209834 3994490 797892..798854 1 NC_007946.1 glycosyl transferase 798854 ybiB 3994490 ybiB Escherichia coli UTI89 glycosyl transferase YP_539820.1 797892 D 364106 CDS YP_539821.1 91209835 3994491 798995..800080 1 NC_007946.1 hypothetical protein 800080 ybiC 3994491 ybiC Escherichia coli UTI89 hypothetical protein YP_539821.1 798995 D 364106 CDS YP_539822.1 91209836 3994492 complement(800308..800568) 1 NC_007946.1 hypothetical protein 800568 ybiJ 3994492 ybiJ Escherichia coli UTI89 hypothetical protein YP_539822.1 800308 R 364106 CDS YP_539823.1 91209837 3994493 complement(800833..801099) 1 NC_007946.1 hypothetical protein 801099 3994493 UTI89_C0806 Escherichia coli UTI89 hypothetical protein YP_539823.1 800833 R 364106 CDS YP_539824.1 91209838 3994494 complement(801173..801886) 1 NC_007946.1 hydroxylase 801886 ybiX 3994494 ybiX Escherichia coli UTI89 hydroxylase YP_539824.1 801173 R 364106 CDS YP_539825.1 91209839 3994495 complement(802066..804348) 1 NC_007946.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 804348 ybiL 3994495 ybiL Escherichia coli UTI89 catecholate siderophore receptor Fiu YP_539825.1 802066 R 364106 CDS YP_539826.1 91209840 3994496 complement(804613..805017) 1 NC_007946.1 hypothetical protein 805017 ybiM 3994496 ybiM Escherichia coli UTI89 hypothetical protein YP_539826.1 804613 R 364106 CDS YP_539827.1 91209841 3994497 805059..806075 1 NC_007946.1 SAM-dependent methyltransferase 806075 ybiN 3994497 ybiN Escherichia coli UTI89 SAM-dependent methyltransferase YP_539827.1 805059 D 364106 CDS YP_539828.2 162138468 3994498 complement(806072..808297) 1 NC_007946.1 hypothetical protein 808297 ybiO 3994498 ybiO Escherichia coli UTI89 hypothetical protein YP_539828.2 806072 R 364106 CDS YP_539829.1 91209843 3994499 complement(808414..809136) 1 NC_007946.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 809136 glnQ 3994499 glnQ Escherichia coli UTI89 glutamine ABC transporter ATP-binding protein YP_539829.1 808414 R 364106 CDS YP_539830.1 91209844 3992638 complement(809133..809792) 1 NC_007946.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 809792 glnP 3992638 glnP Escherichia coli UTI89 glutamine ABC transporter permease YP_539830.1 809133 R 364106 CDS YP_539831.1 91209845 3992639 complement(809931..810677) 1 NC_007946.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter substrate-binding protein 810677 glnH 3992639 glnH Escherichia coli UTI89 glutamine ABC transporter substrate-binding protein YP_539831.1 809931 R 364106 CDS YP_539832.1 91209846 3992640 complement(810723..811016) 1 NC_007946.1 hypothetical protein 811016 3992640 UTI89_C0815 Escherichia coli UTI89 hypothetical protein YP_539832.1 810723 R 364106 CDS YP_539833.1 91209847 3992641 complement(811081..811677) 1 NC_007946.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 811677 dps 3992641 dps Escherichia coli UTI89 DNA starvation/stationary phase protection protein Dps YP_539833.1 811081 R 364106 CDS YP_539834.1 91209848 3992642 complement(811883..812782) 1 NC_007946.1 threonine and homoserine efflux system 812782 ybiF 3992642 ybiF Escherichia coli UTI89 threonine and homoserine efflux system YP_539834.1 811883 R 364106 CDS YP_539835.1 91209849 3992643 813117..813638 1 NC_007946.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 813638 ompX 3992643 ompX Escherichia coli UTI89 outer membrane protein X YP_539835.1 813117 D 364106 CDS YP_539836.1 91209850 3992644 complement(813688..815271) 1 NC_007946.1 hypothetical protein 815271 ybiP 3992644 ybiP Escherichia coli UTI89 hypothetical protein YP_539836.1 813688 R 364106 CDS YP_539837.1 91209851 3992645 complement(815543..815671) 1 NC_007946.1 hypothetical protein 815671 3992645 UTI89_C0820 Escherichia coli UTI89 hypothetical protein YP_539837.1 815543 R 364106 CDS YP_539838.1 91209852 3992646 815857..816324 1 NC_007946.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 816324 mntR 3992646 mntR Escherichia coli UTI89 manganese transport regulator MntR YP_539838.1 815857 D 364106 CDS YP_539839.1 91209853 3992647 816321..817439 1 NC_007946.1 hypothetical protein 817439 ybiR 3992647 ybiR Escherichia coli UTI89 hypothetical protein YP_539839.1 816321 D 364106 CDS YP_539840.1 91209854 3992648 complement(817497..818417) 1 NC_007946.1 hypothetical protein 818417 ybiS 3992648 ybiS Escherichia coli UTI89 hypothetical protein YP_539840.1 817497 R 364106 CDS YP_539841.1 91209855 3992649 818636..820228 1 NC_007946.1 ABC transporter ATP-binding protein 820228 ybiT 3992649 ybiT Escherichia coli UTI89 ABC transporter ATP-binding protein YP_539841.1 818636 D 364106 CDS YP_539842.1 91209856 3992650 complement(820428..821243) 1 NC_007946.1 hypothetical protein 821243 ybiV 3992650 ybiV Escherichia coli UTI89 hypothetical protein YP_539842.1 820428 R 364106 CDS YP_539843.1 91209857 3992651 complement(821389..823821) 1 NC_007946.1 formate acetyltransferase 3 823821 ybiW 3992651 ybiW Escherichia coli UTI89 formate acetyltransferase 3 YP_539843.1 821389 R 364106 CDS YP_539844.1 91209858 3992652 complement(823827..824753) 1 NC_007946.1 pyruvate formate-lyase 3 activating enzyme 824753 3992652 UTI89_C0827 Escherichia coli UTI89 pyruvate formate-lyase 3 activating enzyme YP_539844.1 823827 R 364106 CDS YP_539845.2 162138467 3992653 824857..825519 1 NC_007946.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 825519 3992653 UTI89_C0828 Escherichia coli UTI89 fructose-6-phosphate aldolase YP_539845.2 824857 D 364106 CDS YP_539846.1 91209860 3992654 complement(825595..826344) 1 NC_007946.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 826344 moeB 3992654 moeB Escherichia coli UTI89 molybdopterin biosynthesis protein MoeB YP_539846.1 825595 R 364106 CDS YP_539847.1 91209861 3992655 complement(826344..827579) 1 NC_007946.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 827579 moeA 3992655 moeA Escherichia coli UTI89 molybdopterin biosynthesis protein MoeA YP_539847.1 826344 R 364106 CDS YP_539848.1 91209862 3992656 827783..828748 1 NC_007946.1 L-asparaginase 828748 ybiK 3992656 ybiK Escherichia coli UTI89 L-asparaginase YP_539848.1 827783 D 364106 CDS YP_539849.1 91209863 3992657 828627..830606 1 NC_007946.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 830606 3992657 UTI89_C0832 Escherichia coli UTI89 glutathione transporter ATP-binding protein YP_539849.1 828627 D 364106 CDS YP_539850.1 91209864 3993139 830368..832164 1 NC_007946.1 hemin-binding lipoprotein 832164 3993139 UTI89_C0833 Escherichia coli UTI89 hemin-binding lipoprotein YP_539850.1 830368 D 364106 CDS YP_539851.1 91209865 3993140 832182..833102 1 NC_007946.1 ABC transporter permease 833102 yliC 3993140 yliC Escherichia coli UTI89 ABC transporter permease YP_539851.1 832182 D 364106 CDS YP_539852.1 91209866 3993141 833105..834016 1 NC_007946.1 transport system permease 834016 3993141 UTI89_C0835 Escherichia coli UTI89 transport system permease YP_539852.1 833105 D 364106 CDS YP_539853.1 91209867 3993142 834193..836541 1 NC_007946.1 hypothetical protein 836541 yliE 3993142 yliE Escherichia coli UTI89 hypothetical protein YP_539853.1 834193 D 364106 CDS YP_539854.1 91209868 3993143 836549..837877 1 NC_007946.1 hypothetical protein 837877 yliF 3993143 yliF Escherichia coli UTI89 hypothetical protein YP_539854.1 836549 D 364106 CDS YP_539855.1 91209869 3993144 complement(837924..839249) 1 NC_007946.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 839249 rimO 3993144 rimO Escherichia coli UTI89 ribosomal protein S12 methylthiotransferase YP_539855.1 837924 R 364106 CDS YP_539856.2 162138466 3993145 839462..839845 1 NC_007946.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 839845 bssR 3993145 bssR Escherichia coli UTI89 biofilm formation regulatory protein BssR YP_539856.2 839462 D 364106 CDS YP_539857.1 91209871 3993146 839956..841071 1 NC_007946.1 hypothetical protein 841071 yliI 3993146 yliI Escherichia coli UTI89 hypothetical protein YP_539857.1 839956 D 364106 CDS YP_539858.1 91209872 3993147 complement(841068..841700) 1 NC_007946.1 GST-like protein 841700 yliJ 3993147 yliJ Escherichia coli UTI89 GST-like protein YP_539858.1 841068 R 364106 CDS YP_539859.1 91209873 3993148 841920..843143 1 NC_007946.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 843143 dacC 3993148 dacC Escherichia coli UTI89 D-alanyl-D-alanine carboxypeptidase fraction C YP_539859.1 841920 D 364106 CDS YP_539860.1 91209874 3993149 complement(843190..843948) 1 NC_007946.1 DNA-binding transcriptional repressor DeoR 843948 deoR 3993149 deoR Escherichia coli UTI89 DNA-binding transcriptional repressor DeoR YP_539860.1 843190 R 364106 CDS YP_539861.1 91209875 3993150 complement(844006..844602) 1 NC_007946.1 undecaprenyl pyrophosphate phosphatase 844602 ybjG 3993150 ybjG Escherichia coli UTI89 undecaprenyl pyrophosphate phosphatase YP_539861.1 844006 R 364106 CDS YP_539862.1 91209876 3993151 844857..846119 1 NC_007946.1 MdfA/Cmr MFS multidrug transporter 846119 cmr 3993151 cmr Escherichia coli UTI89 MdfA/Cmr MFS multidrug transporter YP_539862.1 844857 D 364106 CDS YP_539863.1 91209877 3993152 complement(846160..846426) 1 NC_007946.1 hypothetical protein 846426 ybjH 3993152 ybjH Escherichia coli UTI89 hypothetical protein YP_539863.1 846160 R 364106 CDS YP_539864.1 91209878 3993153 complement(846511..847329) 1 NC_007946.1 hypothetical protein 847329 ybjI 3993153 ybjI Escherichia coli UTI89 hypothetical protein YP_539864.1 846511 R 364106 CDS YP_539865.1 91209879 3993154 complement(847326..848597) 1 NC_007946.1 DEOR-type transcriptional regulator 848597 ybjJ 3993154 ybjJ Escherichia coli UTI89 DEOR-type transcriptional regulator YP_539865.1 847326 R 364106 CDS YP_539866.1 91209880 3993155 848588..849154 1 NC_007946.1 DEOR-type transcriptional regulator 849154 ybjK 3993155 ybjK Escherichia coli UTI89 DEOR-type transcriptional regulator YP_539866.1 848588 D 364106 CDS YP_539867.1 91209881 3993156 complement(849329..851014) 1 NC_007946.1 hypothetical protein 851014 ybjL 3993156 ybjL Escherichia coli UTI89 hypothetical protein YP_539867.1 849329 R 364106 CDS YP_539868.1 91209882 3993157 851284..851661 1 NC_007946.1 hypothetical protein 851661 ybjM 3993157 ybjM Escherichia coli UTI89 hypothetical protein YP_539868.1 851284 D 364106 CDS YP_539869.2 162138465 3993659 complement(851691..851948) 1 NC_007946.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 851948 grxA 3993659 grxA Escherichia coli UTI89 glutaredoxin 1 YP_539869.2 851691 R 364106 CDS YP_539870.1 91209884 3993660 852108..852395 1 NC_007946.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 852395 ybjC 3993660 ybjC Escherichia coli UTI89 hypothetical protein YP_539870.1 852108 D 364106 CDS YP_539871.1 91209885 3993661 852379..853101 1 NC_007946.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 853101 nfsA 3993661 nfsA Escherichia coli UTI89 nitroreductase A YP_539871.1 852379 D 364106 CDS YP_539872.1 91209886 3993662 853162..854064 1 NC_007946.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 854064 rimK 3993662 rimK Escherichia coli UTI89 ribosomal protein S6 modification protein YP_539872.1 853162 D 364106 CDS YP_539873.1 91209887 3993663 854104..854628 1 NC_007946.1 sensory transduction regulator 854628 ybjN 3993663 ybjN Escherichia coli UTI89 sensory transduction regulator YP_539873.1 854104 D 364106 CDS YP_539874.1 91209888 3993664 854834..856090 1 NC_007946.1 putrescine ABC transporter substrate-binding protein 856090 potF 3993664 potF Escherichia coli UTI89 putrescine ABC transporter substrate-binding protein YP_539874.1 854834 D 364106 CDS YP_539875.2 162138464 3993665 856185..857318 1 NC_007946.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding protein 857318 potG 3993665 potG Escherichia coli UTI89 putrescine transporter ATP-binding protein YP_539875.2 856185 D 364106 CDS YP_539876.1 91209890 3993666 857328..858281 1 NC_007946.1 putrescine ABC transporter 858281 potH 3993666 potH Escherichia coli UTI89 putrescine ABC transporter YP_539876.1 857328 D 364106 CDS YP_539877.1 91209891 3993667 858236..859123 1 NC_007946.1 putrescine ABC transporter 859123 potI 3993667 potI Escherichia coli UTI89 putrescine ABC transporter YP_539877.1 858236 D 364106 CDS YP_539878.1 91209892 3993668 859183..859671 1 NC_007946.1 hypothetical protein 859671 ybjO 3993668 ybjO Escherichia coli UTI89 hypothetical protein YP_539878.1 859183 D 364106 CDS YP_539879.1 91209893 3993669 859712..860839 1 NC_007946.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 860839 rumB 3993669 rumB Escherichia coli UTI89 23S rRNA methyluridine methyltransferase YP_539879.1 859712 D 364106 CDS YP_539880.1 91209894 3993670 complement(860868..861650) 1 NC_007946.1 arginine-binding periplasmic protein 2 861650 artJ 3993670 artJ Escherichia coli UTI89 arginine-binding periplasmic protein 2 YP_539880.1 860868 R 364106 CDS YP_539881.1 91209895 3993671 complement(861825..862493) 1 NC_007946.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 862493 artM 3993671 artM Escherichia coli UTI89 arginine transporter permease subunit ArtM YP_539881.1 861825 R 364106 CDS YP_539882.1 91209896 3993672 complement(862493..863209) 1 NC_007946.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 863209 artQ 3993672 artQ Escherichia coli UTI89 arginine transporter permease subunit ArtQ YP_539882.1 862493 R 364106 CDS YP_539883.1 91209897 3993673 complement(863216..863947) 1 NC_007946.1 arginine-binding periplasmic protein 1 863947 artI 3993673 artI Escherichia coli UTI89 arginine-binding periplasmic protein 1 YP_539883.1 863216 R 364106 CDS YP_539884.2 162138463 3993674 complement(863965..864693) 1 NC_007946.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 864693 artP 3993674 artP Escherichia coli UTI89 arginine transporter ATP-binding subunit YP_539884.2 863965 R 364106 CDS YP_539885.1 91209899 3993675 complement(864911..865450) 1 NC_007946.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 865450 ybjP 3993675 ybjP Escherichia coli UTI89 lipoprotein YP_539885.1 864911 R 364106 CDS YP_539886.1 91209900 3993676 865552..865875 1 NC_007946.1 hypothetical protein 865875 ybjQ 3993676 ybjQ Escherichia coli UTI89 hypothetical protein YP_539886.1 865552 D 364106 CDS YP_539887.1 91209901 3993677 865872..866702 1 NC_007946.1 N-acetylmuramoyl-L-alanine amidase 866702 ybjR 3993677 ybjR Escherichia coli UTI89 N-acetylmuramoyl-L-alanine amidase YP_539887.1 865872 D 364106 CDS YP_539888.1 91209902 3993678 complement(866699..867775) 1 NC_007946.1 hypothetical protein 867775 ybjS 3993678 ybjS Escherichia coli UTI89 hypothetical protein YP_539888.1 866699 R 364106 CDS YP_539889.1 91209903 3993102 complement(867811..869316) 1 NC_007946.1 hypothetical protein 869316 ybjT 3993102 ybjT Escherichia coli UTI89 hypothetical protein YP_539889.1 867811 R 364106 CDS YP_539890.1 91209904 3993103 complement(869252..870253) 1 NC_007946.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 870253 ybjU 3993103 ybjU Escherichia coli UTI89 L-threonine aldolase YP_539890.1 869252 R 364106 CDS YP_539891.1 91209905 3993104 complement(870290..872008) 1 NC_007946.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 872008 poxB 3993104 poxB Escherichia coli UTI89 pyruvate dehydrogenase YP_539891.1 870290 R 364106 CDS YP_539892.1 91209906 3993105 complement(872141..873115) 1 NC_007946.1 HCP oxidoreductase, NADH-dependent 873115 hcr 3993105 hcr Escherichia coli UTI89 HCP oxidoreductase, NADH-dependent YP_539892.1 872141 R 364106 CDS YP_539893.1 91209907 3993106 complement(873121..874779) 1 NC_007946.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 874779 ybjW 3993106 ybjW Escherichia coli UTI89 hydroxylamine reductase YP_539893.1 873121 R 364106 CDS YP_539894.1 91209908 3993107 complement(874917..875816) 1 NC_007946.1 hypothetical protein 875816 ybjE 3993107 ybjE Escherichia coli UTI89 hypothetical protein YP_539894.1 874917 R 364106 CDS YP_539895.1 91209909 3993108 complement(876137..876838) 1 NC_007946.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 876838 aqpZ 3993108 aqpZ Escherichia coli UTI89 aquaporin Z YP_539895.1 876137 R 364106 CDS YP_539896.1 91209910 3993109 complement(877045..877200) 1 NC_007946.1 hypothetical protein 877200 3993109 UTI89_C0879 Escherichia coli UTI89 hypothetical protein YP_539896.1 877045 R 364106 CDS YP_539897.1 91209911 3993110 877258..878916 1 NC_007946.1 hypothetical protein 878916 ybjD 3993110 ybjD Escherichia coli UTI89 hypothetical protein YP_539897.1 877258 D 364106 CDS YP_539898.1 91209912 3993111 complement(878913..879905) 1 NC_007946.1 hypothetical protein 879905 ybjX 3993111 ybjX Escherichia coli UTI89 hypothetical protein YP_539898.1 878913 R 364106 CDS YP_539899.1 91209913 3993112 879974..880108 1 NC_007946.1 hypothetical protein 880108 3993112 UTI89_C0882 Escherichia coli UTI89 hypothetical protein YP_539899.1 879974 D 364106 CDS YP_539900.2 162138462 3993113 880020..881135 1 NC_007946.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 881135 macA 3993113 macA Escherichia coli UTI89 macrolide transporter subunit MacA YP_539900.2 880020 D 364106 CDS YP_539901.1 91209915 3993114 881132..883078 1 NC_007946.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 883078 ybjZ 3993114 ybjZ Escherichia coli UTI89 macrolide transporter ATP-binding /permease YP_539901.1 881132 D 364106 CDS YP_539902.1 91209916 3993115 complement(883151..883405) 1 NC_007946.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 883405 cspD 3993115 cspD Escherichia coli UTI89 stationary phase/starvation inducible regulatory protein CspD YP_539902.1 883151 R 364106 CDS YP_539903.1 91209917 3993116 complement(883249..883533) 1 NC_007946.1 hypothetical protein 883533 3993116 UTI89_C0886 Escherichia coli UTI89 hypothetical protein YP_539903.1 883249 R 364106 CDS YP_539904.1 91209918 3993117 883698..884018 1 NC_007946.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 884018 clpS 3993117 clpS Escherichia coli UTI89 ATP-dependent Clp protease adaptor protein ClpS YP_539904.1 883698 D 364106 CDS YP_539905.2 162138461 3993118 884049..886325 1 NC_007946.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 886325 clpA 3993118 clpA Escherichia coli UTI89 ATP-dependent Clp protease ATP-binding subunit YP_539905.2 884049 D 364106 CDS YP_539906.1 91209920 3993119 complement(886443..886715) 1 NC_007946.1 hypothetical protein 886715 3993119 UTI89_C0889 Escherichia coli UTI89 hypothetical protein YP_539906.1 886443 R 364106 CDS YP_539907.1 91209921 3993120 887218..888201 1 NC_007946.1 hypothetical protein 888201 3993120 UTI89_C0890 Escherichia coli UTI89 hypothetical protein YP_539907.1 887218 D 364106 CDS YP_539908.1 91209922 3993063 888198..891431 1 NC_007946.1 hypothetical protein 891431 3993063 UTI89_C0891 Escherichia coli UTI89 hypothetical protein YP_539908.1 888198 D 364106 CDS YP_539909.1 91209923 3993064 891761..893068 1 NC_007946.1 hypothetical protein 893068 3993064 UTI89_C0892 Escherichia coli UTI89 hypothetical protein YP_539909.1 891761 D 364106 CDS YP_539910.1 91209924 3993065 893065..893280 1 NC_007946.1 hypothetical protein 893280 3993065 UTI89_C0893 Escherichia coli UTI89 hypothetical protein YP_539910.1 893065 D 364106 CDS YP_539911.1 91209925 3993066 893347..893988 1 NC_007946.1 hypothetical protein 893988 3993066 UTI89_C0894 Escherichia coli UTI89 hypothetical protein YP_539911.1 893347 D 364106 CDS YP_539912.1 91209926 3993067 893999..895000 1 NC_007946.1 hypothetical protein 895000 3993067 UTI89_C0895 Escherichia coli UTI89 hypothetical protein YP_539912.1 893999 D 364106 CDS YP_539913.1 91209927 3993068 895011..895565 1 NC_007946.1 hypothetical protein 895565 3993068 UTI89_C0896 Escherichia coli UTI89 hypothetical protein YP_539913.1 895011 D 364106 CDS YP_539914.1 91209928 3993070 896133..896453 1 NC_007946.1 hypothetical protein 896453 3993070 UTI89_C0898 Escherichia coli UTI89 hypothetical protein YP_539914.1 896133 D 364106 CDS YP_539915.1 91209929 3993071 complement(896607..896825) 1 NC_007946.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 896825 infA 3993071 infA Escherichia coli UTI89 translation initiation factor IF-1 YP_539915.1 896607 R 364106 CDS YP_539916.1 91209930 3993072 complement(897110..897814) 1 NC_007946.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 897814 aat 3993072 aat Escherichia coli UTI89 leucyl/phenylalanyl-tRNA--protein transferase YP_539916.1 897110 R 364106 CDS YP_539917.1 91209931 3993073 complement(897856..899577) 1 NC_007946.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 899577 cydC 3993073 cydC Escherichia coli UTI89 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_539917.1 897856 R 364106 CDS YP_539918.1 91209932 3993074 complement(899578..901344) 1 NC_007946.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 901344 cydD 3993074 cydD Escherichia coli UTI89 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_539918.1 899578 R 364106 CDS YP_539919.1 91209933 3993075 complement(901467..902552) 1 NC_007946.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 902552 trxB 3993075 trxB Escherichia coli UTI89 thioredoxin reductase YP_539919.1 901467 R 364106 CDS YP_539920.2 162138460 3993076 902976..903470 1 NC_007946.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 903470 lrp 3993076 lrp Escherichia coli UTI89 leucine-responsive transcriptional regulator YP_539920.2 902976 D 364106 CDS YP_539921.1 91209935 3993077 903605..907648 1 NC_007946.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 907648 ftsK 3993077 ftsK Escherichia coli UTI89 DNA translocase FtsK YP_539921.1 903605 D 364106 CDS YP_539922.1 91209936 3993078 907804..908418 1 NC_007946.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 908418 lolA 3993078 lolA Escherichia coli UTI89 outer-membrane lipoprotein carrier protein YP_539922.1 907804 D 364106 CDS YP_539923.1 91209937 3993079 908429..909772 1 NC_007946.1 recombination factor protein RarA 909772 ycaJ 3993079 ycaJ Escherichia coli UTI89 recombination factor protein RarA YP_539923.1 908429 D 364106 CDS YP_539924.1 91209938 3993080 909863..911155 1 NC_007946.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 911155 serS 3993080 serS Escherichia coli UTI89 seryl-tRNA synthetase YP_539924.1 909863 D 364106 CDS YP_539925.1 91209939 3993081 911268..911546 1 NC_007946.1 hypothetical protein 911546 3993081 UTI89_C0909 Escherichia coli UTI89 hypothetical protein YP_539925.1 911268 D 364106 CDS YP_539926.1 91209940 3992988 complement(911458..911598) 1 NC_007946.1 hypothetical protein 911598 3992988 UTI89_C0910 Escherichia coli UTI89 hypothetical protein YP_539926.1 911458 R 364106 CDS YP_539927.1 91209941 3992989 911530..911793 1 NC_007946.1 hypothetical protein 911793 3992989 UTI89_C0911 Escherichia coli UTI89 hypothetical protein YP_539927.1 911530 D 364106 CDS YP_539928.1 91209942 3992990 complement(911790..912050) 1 NC_007946.1 hypothetical protein 912050 3992990 UTI89_C0912 Escherichia coli UTI89 hypothetical protein YP_539928.1 911790 R 364106 CDS YP_539929.1 91209943 3992991 complement(912093..913202) 1 NC_007946.1 bacteriophage late gene regulator 913202 3992991 UTI89_C0913 Escherichia coli UTI89 bacteriophage late gene regulator YP_539929.1 912093 R 364106 CDS YP_539930.1 91209944 3992992 913360..914544 1 NC_007946.1 tail sheath protein of prophage CP-933T 914544 3992992 UTI89_C0914 Escherichia coli UTI89 tail sheath protein of prophage CP-933T YP_539930.1 913360 D 364106 CDS YP_539931.1 91209945 3992993 914544..915056 1 NC_007946.1 tail fiber component of prophage CP-933T 915056 3992993 UTI89_C0915 Escherichia coli UTI89 tail fiber component of prophage CP-933T YP_539931.1 914544 D 364106 CDS YP_539932.1 91209946 3992994 915112..915486 1 NC_007946.1 prophage CP-933T hypothetical protein 915486 3992994 UTI89_C0916 Escherichia coli UTI89 prophage CP-933T hypothetical protein YP_539932.1 915112 D 364106 CDS YP_539933.1 91209947 3992995 915414..915650 1 NC_007946.1 phage tail protein 915650 3992995 UTI89_C0917 Escherichia coli UTI89 phage tail protein YP_539933.1 915414 D 364106 CDS YP_539934.1 91209948 3992996 915637..918444 1 NC_007946.1 phage tail protein 918444 3992996 UTI89_C0918 Escherichia coli UTI89 phage tail protein YP_539934.1 915637 D 364106 CDS YP_539935.1 91209949 3992997 918451..918945 1 NC_007946.1 tail fiber protein of prophage CP-933T 918945 3992997 UTI89_C0919 Escherichia coli UTI89 tail fiber protein of prophage CP-933T YP_539935.1 918451 D 364106 CDS YP_539936.1 91209950 3992998 complement(918974..919573) 1 NC_007946.1 DNA-invertase 919573 pin 3992998 pin Escherichia coli UTI89 DNA-invertase YP_539936.1 918974 R 364106 CDS YP_539937.1 91209951 3992999 919678..920514 1 NC_007946.1 tail fiber protein gpH 920514 3992999 UTI89_C0921 Escherichia coli UTI89 tail fiber protein gpH YP_539937.1 919678 D 364106 CDS YP_539938.1 91209952 3993000 920518..921045 1 NC_007946.1 tail fiber assembly 921045 3993000 UTI89_C0922 Escherichia coli UTI89 tail fiber assembly YP_539938.1 920518 D 364106 CDS YP_539939.1 91209953 3993001 complement(921074..921607) 1 NC_007946.1 tail fiber assembly protein 921607 3993001 UTI89_C0923 Escherichia coli UTI89 tail fiber assembly protein YP_539939.1 921074 R 364106 CDS YP_539940.1 91209954 3993002 complement(921610..923595) 1 NC_007946.1 phage protein gpH 923595 3993002 UTI89_C0924 Escherichia coli UTI89 phage protein gpH YP_539940.1 921610 R 364106 CDS YP_539941.1 91209955 3993003 complement(923598..924128) 1 NC_007946.1 phage protein gpI 924128 3993003 UTI89_C0925 Escherichia coli UTI89 phage protein gpI YP_539941.1 923598 R 364106 CDS YP_539942.1 91209956 3993004 complement(924121..925017) 1 NC_007946.1 phage baseplate assembly protein 925017 3993004 UTI89_C0926 Escherichia coli UTI89 phage baseplate assembly protein YP_539942.1 924121 R 364106 CDS YP_539943.1 91209957 3993005 complement(925021..925371) 1 NC_007946.1 phage baseplate assembly protein 925371 3993005 UTI89_C0927 Escherichia coli UTI89 phage baseplate assembly protein YP_539943.1 925021 R 364106 CDS YP_539944.1 91209958 3993006 complement(925368..925949) 1 NC_007946.1 phage protein gp15 925949 3993006 UTI89_C0928 Escherichia coli UTI89 phage protein gp15 YP_539944.1 925368 R 364106 CDS YP_539945.1 91209959 3993580 complement(925946..926590) 1 NC_007946.1 tail completion phage protein 926590 3993580 UTI89_C0929 Escherichia coli UTI89 tail completion phage protein YP_539945.1 925946 R 364106 CDS YP_539946.1 91209960 3993581 complement(926574..927041) 1 NC_007946.1 tail completion phage protein 927041 3993581 UTI89_C0930 Escherichia coli UTI89 tail completion phage protein YP_539946.1 926574 R 364106 CDS YP_539947.1 91209961 3993582 complement(927179..927730) 1 NC_007946.1 hypothetical protein 927730 3993582 UTI89_C0931 Escherichia coli UTI89 hypothetical protein YP_539947.1 927179 R 364106 CDS YP_539948.1 91209962 3993583 complement(927583..927975) 1 NC_007946.1 endolysin 927975 3993583 UTI89_C0932 Escherichia coli UTI89 endolysin YP_539948.1 927583 R 364106 CDS YP_539949.1 91209963 3993584 complement(927972..928295) 1 NC_007946.1 phage holin 928295 3993584 UTI89_C0933 Escherichia coli UTI89 phage holin YP_539949.1 927972 R 364106 CDS YP_539950.1 91209964 3993585 complement(928298..928498) 1 NC_007946.1 phage tail protein 928498 3993585 UTI89_C0934 Escherichia coli UTI89 phage tail protein YP_539950.1 928298 R 364106 CDS YP_539951.1 91209965 3993586 complement(928498..928992) 1 NC_007946.1 capsid completion protein 928992 3993586 UTI89_C0935 Escherichia coli UTI89 capsid completion protein YP_539951.1 928498 R 364106 CDS YP_539952.1 91209966 3993587 complement(929094..929894) 1 NC_007946.1 hypothetical protein 929894 3993587 UTI89_C0936 Escherichia coli UTI89 hypothetical protein YP_539952.1 929094 R 364106 CDS YP_539953.1 91209967 3993588 complement(929940..930992) 1 NC_007946.1 major capsid protein 930992 3993588 UTI89_C0937 Escherichia coli UTI89 major capsid protein YP_539953.1 929940 R 364106 CDS YP_539954.1 91209968 3993589 complement(931016..931852) 1 NC_007946.1 capsid scaffolding protein 931852 3993589 UTI89_C0938 Escherichia coli UTI89 capsid scaffolding protein YP_539954.1 931016 R 364106 CDS YP_539955.1 91209969 3993590 932007..933758 1 NC_007946.1 phage protein gpP 933758 3993590 UTI89_C0939 Escherichia coli UTI89 phage protein gpP YP_539955.1 932007 D 364106 CDS YP_539956.1 91209970 3993591 933758..934804 1 NC_007946.1 hypothetical protein 934804 3993591 UTI89_C0940 Escherichia coli UTI89 hypothetical protein YP_539956.1 933758 D 364106 CDS YP_539957.1 91209971 3993592 934907..935263 1 NC_007946.1 hypothetical protein 935263 3993592 UTI89_C0941 Escherichia coli UTI89 hypothetical protein YP_539957.1 934907 D 364106 CDS YP_539958.1 91209972 3993593 complement(935295..935555) 1 NC_007946.1 hypothetical protein 935555 3993593 UTI89_C0942 Escherichia coli UTI89 hypothetical protein YP_539958.1 935295 R 364106 CDS YP_539959.1 91209973 3993594 complement(935566..935829) 1 NC_007946.1 prophage CP-933R hypothetical protein 935829 3993594 UTI89_C0943 Escherichia coli UTI89 prophage CP-933R hypothetical protein YP_539959.1 935566 R 364106 CDS YP_539960.1 91209974 3993595 complement(935831..936328) 1 NC_007946.1 hypothetical protein 936328 3993595 UTI89_C0944 Escherichia coli UTI89 hypothetical protein YP_539960.1 935831 R 364106 CDS YP_539961.1 91209975 3993596 complement(936325..936639) 1 NC_007946.1 hypothetical protein 936639 3993596 UTI89_C0945 Escherichia coli UTI89 hypothetical protein YP_539961.1 936325 R 364106 CDS YP_539962.1 91209976 3993597 complement(936636..936968) 1 NC_007946.1 ATP-dependent specificity component of ClpP serine protease, chaperone 936968 3993597 UTI89_C0946 Escherichia coli UTI89 ATP-dependent specificity component of ClpP serine protease, chaperone YP_539962.1 936636 R 364106 CDS YP_539963.1 91209977 3993598 complement(937032..937343) 1 NC_007946.1 prophage CP-933T stability/partitioning protein 937343 3993598 UTI89_C0947 Escherichia coli UTI89 prophage CP-933T stability/partitioning protein YP_539963.1 937032 R 364106 CDS YP_539964.1 91209978 3993599 complement(937348..938307) 1 NC_007946.1 prophage CP-933T stability/partitioning protein 938307 3993599 UTI89_C0948 Escherichia coli UTI89 prophage CP-933T stability/partitioning protein YP_539964.1 937348 R 364106 CDS YP_539965.1 91209979 3994214 complement(938384..941206) 1 NC_007946.1 prophage CP-933T replication protein 941206 3994214 UTI89_C0949 Escherichia coli UTI89 prophage CP-933T replication protein YP_539965.1 938384 R 364106 CDS YP_539966.1 91209980 3994215 complement(941213..941578) 1 NC_007946.1 prophage CP-933T hypothetical protein 941578 3994215 UTI89_C0950 Escherichia coli UTI89 prophage CP-933T hypothetical protein YP_539966.1 941213 R 364106 CDS YP_539967.1 91209981 3994216 complement(941651..941881) 1 NC_007946.1 prophage CP-933T hypothetical protein 941881 3994216 UTI89_C0951 Escherichia coli UTI89 prophage CP-933T hypothetical protein YP_539967.1 941651 R 364106 CDS YP_539968.1 91209982 3994217 941750..942025 1 NC_007946.1 hypothetical protein 942025 3994217 UTI89_C0952 Escherichia coli UTI89 hypothetical protein YP_539968.1 941750 D 364106 CDS YP_539969.1 91209983 3994218 complement(942252..943076) 1 NC_007946.1 serine protease 943076 3994218 UTI89_C0953 Escherichia coli UTI89 serine protease YP_539969.1 942252 R 364106 CDS YP_539970.1 91209984 3994219 complement(943073..943285) 1 NC_007946.1 hypothetical protein 943285 3994219 UTI89_C0954 Escherichia coli UTI89 hypothetical protein YP_539970.1 943073 R 364106 CDS YP_539972.1 91209986 3994221 complement(943297..943596) 1 NC_007946.1 prophage CP-933T hypothetical protein 943596 3994221 UTI89_C0956 Escherichia coli UTI89 prophage CP-933T hypothetical protein YP_539972.1 943297 R 364106 CDS YP_539973.1 91209987 3994222 complement(943593..943859) 1 NC_007946.1 hypothetical protein 943859 3994222 UTI89_C0957 Escherichia coli UTI89 hypothetical protein YP_539973.1 943593 R 364106 CDS YP_539974.1 91209988 3994223 complement(943856..944059) 1 NC_007946.1 hypothetical protein 944059 3994223 UTI89_C0958 Escherichia coli UTI89 hypothetical protein YP_539974.1 943856 R 364106 CDS YP_539975.1 91209989 3994224 complement(944083..944493) 1 NC_007946.1 prophage CP-933T hypothetical protein 944493 3994224 UTI89_C0959 Escherichia coli UTI89 prophage CP-933T hypothetical protein YP_539975.1 944083 R 364106 CDS YP_539976.1 91209990 3994225 complement(944697..944939) 1 NC_007946.1 hypothetical protein 944939 3994225 UTI89_C0960 Escherichia coli UTI89 hypothetical protein YP_539976.1 944697 R 364106 CDS YP_539977.1 91209991 3994226 complement(944951..945238) 1 NC_007946.1 hypothetical protein 945238 3994226 UTI89_C0961 Escherichia coli UTI89 hypothetical protein YP_539977.1 944951 R 364106 CDS YP_539978.1 91209992 3994227 complement(945249..945599) 1 NC_007946.1 hypothetical protein 945599 3994227 UTI89_C0962 Escherichia coli UTI89 hypothetical protein YP_539978.1 945249 R 364106 CDS YP_539979.1 91209993 3994228 complement(945933..946355) 1 NC_007946.1 hypothetical protein 946355 3994228 UTI89_C0963 Escherichia coli UTI89 hypothetical protein YP_539979.1 945933 R 364106 CDS YP_539980.1 91209994 3994229 complement(946360..946881) 1 NC_007946.1 hypothetical protein 946881 3994229 UTI89_C0964 Escherichia coli UTI89 hypothetical protein YP_539980.1 946360 R 364106 CDS YP_539981.1 91209995 3994230 946985..947326 1 NC_007946.1 bacteriophage WPhi phage protein C 947326 3994230 UTI89_C0965 Escherichia coli UTI89 bacteriophage WPhi phage protein C YP_539981.1 946985 D 364106 CDS YP_539982.1 91209996 3994231 947396..948388 1 NC_007946.1 phage integrase 948388 3994231 UTI89_C0966 Escherichia coli UTI89 phage integrase YP_539982.1 947396 D 364106 CDS YP_539983.1 91209997 3994232 948688..951132 1 NC_007946.1 anaerobic dimethyl sulfoxide reductase chain A 951132 dmsA 3994232 dmsA Escherichia coli UTI89 anaerobic dimethyl sulfoxide reductase chain A YP_539983.1 948688 D 364106 CDS YP_539984.1 91209998 3993389 951143..951760 1 NC_007946.1 anaerobic dimethyl sulfoxide reductase subunit B 951760 dmsB 3993389 dmsB Escherichia coli UTI89 anaerobic dimethyl sulfoxide reductase subunit B YP_539984.1 951143 D 364106 CDS YP_539985.1 91209999 3993390 951762..952625 1 NC_007946.1 anaerobic dimethyl sulfoxide reductase subunit C 952625 dmsC 3993390 dmsC Escherichia coli UTI89 anaerobic dimethyl sulfoxide reductase subunit C YP_539985.1 951762 D 364106 CDS YP_539986.1 91210000 3993391 complement(952661..953386) 1 NC_007946.1 protein YcaC 953386 ycaC 3993391 ycaC Escherichia coli UTI89 protein YcaC YP_539986.1 952661 R 364106 CDS YP_539987.1 91210001 3993392 complement(953442..953570) 1 NC_007946.1 hypothetical protein 953570 3993392 UTI89_C0971 Escherichia coli UTI89 hypothetical protein YP_539987.1 953442 R 364106 CDS YP_539988.1 91210002 3993393 953601..954749 1 NC_007946.1 MFS family transporter protein 954749 ycaD 3993393 ycaD Escherichia coli UTI89 MFS family transporter protein YP_539988.1 953601 D 364106 CDS YP_539989.2 162138459 3993394 complement(954846..955586) 1 NC_007946.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 955586 pflA 3993394 pflA Escherichia coli UTI89 pyruvate formate lyase-activating enzyme 1 YP_539989.2 954846 R 364106 CDS YP_539990.1 91210004 3993395 complement(955778..958060) 1 NC_007946.1 formate acetyltransferase 1 958060 pflB 3993395 pflB Escherichia coli UTI89 formate acetyltransferase 1 YP_539990.1 955778 R 364106 CDS YP_539991.1 91210005 3993396 complement(958115..959311) 1 NC_007946.1 formate transporter 959311 focA 3993396 focA Escherichia coli UTI89 formate transporter YP_539991.1 958115 R 364106 CDS YP_539992.1 91210006 3993397 complement(959378..961171) 1 NC_007946.1 hypothetical protein 961171 ycaO 3993397 ycaO Escherichia coli UTI89 hypothetical protein YP_539992.1 959378 R 364106 CDS YP_539993.1 91210007 3993398 961268..961960 1 NC_007946.1 hypothetical protein 961960 ycaP 3993398 ycaP Escherichia coli UTI89 hypothetical protein YP_539993.1 961268 D 364106 CDS YP_539994.1 91210008 3993399 962159..963247 1 NC_007946.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 963247 serC 3993399 serC Escherichia coli UTI89 phosphoserine aminotransferase YP_539994.1 962159 D 364106 CDS YP_539995.1 91210009 3993400 963318..964601 1 NC_007946.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 964601 aroA 3993400 aroA Escherichia coli UTI89 3-phosphoshikimate 1-carboxyvinyltransferase YP_539995.1 963318 D 364106 CDS YP_539996.1 91210010 3993401 964762..965535 1 NC_007946.1 metalloprotease YcaL 965535 ycaL 3993401 ycaL Escherichia coli UTI89 metalloprotease YcaL YP_539996.1 964762 D 364106 CDS YP_539997.1 91210011 3993402 965708..966391 1 NC_007946.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 966391 cmk 3993402 cmk Escherichia coli UTI89 cytidylate kinase YP_539997.1 965708 D 364106 CDS YP_539998.1 91210012 3993403 966502..968175 1 NC_007946.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 968175 rpsA 3993403 rpsA Escherichia coli UTI89 30S ribosomal protein S1 YP_539998.1 966502 D 364106 CDS YP_539999.1 91210013 3993404 968335..968619 1 NC_007946.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 968619 ihfB 3993404 ihfB Escherichia coli UTI89 integration host factor subunit beta YP_539999.1 968335 D 364106 CDS YP_540000.2 162138458 3993405 968825..971089 1 NC_007946.1 hypothetical protein 971089 ycaI 3993405 ycaI Escherichia coli UTI89 hypothetical protein YP_540000.2 968825 D 364106 CDS YP_540001.1 91210015 3993406 971126..972874 1 NC_007946.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 972874 msbA 3993406 msbA Escherichia coli UTI89 lipid transporter ATP-binding/permease YP_540001.1 971126 D 364106 CDS YP_540002.1 91210016 3993407 972871..973857 1 NC_007946.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 973857 lpxK 3993407 lpxK Escherichia coli UTI89 tetraacyldisaccharide 4'-kinase YP_540002.1 972871 D 364106 CDS YP_540003.1 91210017 3993408 973894..975126 1 NC_007946.1 hypothetical protein 975126 ycaQ 3993408 ycaQ Escherichia coli UTI89 hypothetical protein YP_540003.1 973894 D 364106 CDS YP_540004.1 91210018 3992815 975178..975360 1 NC_007946.1 hypothetical protein 975360 ycaR 3992815 ycaR Escherichia coli UTI89 hypothetical protein YP_540004.1 975178 D 364106 CDS YP_540005.1 91210019 3992816 975357..976103 1 NC_007946.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 976103 kdsB 3992816 kdsB Escherichia coli UTI89 3-deoxy-manno-octulosonate cytidylyltransferase YP_540005.1 975357 D 364106 CDS YP_540006.1 91210020 3992817 976257..977150 1 NC_007946.1 hypothetical protein 977150 ycbJ 3992817 ycbJ Escherichia coli UTI89 hypothetical protein YP_540006.1 976257 D 364106 CDS YP_540007.1 91210021 3992818 complement(977127..977906) 1 NC_007946.1 hypothetical protein 977906 ycbC 3992818 ycbC Escherichia coli UTI89 hypothetical protein YP_540007.1 977127 R 364106 CDS YP_540008.1 91210022 3992819 complement(977809..977973) 1 NC_007946.1 hypothetical protein 977973 3992819 UTI89_C0992 Escherichia coli UTI89 hypothetical protein YP_540008.1 977809 R 364106 CDS YP_540009.1 91210023 3992820 978030..978827 1 NC_007946.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 978827 smtA 3992820 smtA Escherichia coli UTI89 metallothionein SmtA YP_540009.1 978030 D 364106 CDS YP_540010.1 91210024 3992821 978824..980146 1 NC_007946.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 980146 mukF 3992821 mukF Escherichia coli UTI89 condesin subunit F YP_540010.1 978824 D 364106 CDS YP_540011.1 91210025 3992822 980100..980831 1 NC_007946.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 980831 mukE 3992822 mukE Escherichia coli UTI89 condesin subunit E YP_540011.1 980100 D 364106 CDS YP_540012.1 91210026 3992823 980831..985291 1 NC_007946.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 985291 mukB 3992823 mukB Escherichia coli UTI89 cell division protein MukB YP_540012.1 980831 D 364106 CDS YP_540013.1 91210027 3992824 985552..987399 1 NC_007946.1 hypothetical protein 987399 ycbB 3992824 ycbB Escherichia coli UTI89 hypothetical protein YP_540013.1 985552 D 364106 CDS YP_540014.1 91210028 3992825 987571..988128 1 NC_007946.1 hypothetical protein 988128 ycbK 3992825 ycbK Escherichia coli UTI89 hypothetical protein YP_540014.1 987571 D 364106 CDS YP_540015.1 91210029 3992826 988155..988802 1 NC_007946.1 hypothetical protein 988802 ycbL 3992826 ycbL Escherichia coli UTI89 hypothetical protein YP_540015.1 988155 D 364106 CDS YP_540016.1 91210030 3992827 complement(988852..990042) 1 NC_007946.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 990042 aspC 3992827 aspC Escherichia coli UTI89 aromatic amino acid aminotransferase YP_540016.1 988852 R 364106 CDS YP_540017.1 91210031 3992828 complement(990227..991315) 1 NC_007946.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 991315 ompF 3992828 ompF Escherichia coli UTI89 outer membrane protein F YP_540017.1 990227 R 364106 CDS YP_540018.1 91210032 3992829 complement(991917..993317) 1 NC_007946.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 993317 asnC 3992829 asnC Escherichia coli UTI89 asparaginyl-tRNA synthetase YP_540018.1 991917 R 364106 CDS YP_540019.1 91210033 3992830 complement(993486..994736) 1 NC_007946.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 994736 pncB 3992830 pncB Escherichia coli UTI89 nicotinate phosphoribosyltransferase YP_540019.1 993486 R 364106 CDS YP_540020.1 91210034 3992831 994954..997566 1 NC_007946.1 aminopeptidase 997566 pepN 3992831 pepN Escherichia coli UTI89 aminopeptidase YP_540020.1 994954 D 364106 CDS YP_540021.1 91210035 3992832 complement(997761..998528) 1 NC_007946.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonate ABC transporter ATP-binding protein 998528 ssuB 3992832 ssuB Escherichia coli UTI89 aliphatic sulfonate ABC transporter ATP-binding protein YP_540021.1 997761 R 364106 CDS YP_540022.1 91210036 3992833 complement(998525..999319) 1 NC_007946.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate ABC transporter permease 999319 ssuC 3992833 ssuC Escherichia coli UTI89 alkanesulfonate ABC transporter permease YP_540022.1 998525 R 364106 CDS YP_540023.1 91210037 3994706 complement(999328..1000473) 1 NC_007946.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1000473 ycbN 3994706 ycbN Escherichia coli UTI89 alkanesulfonate monooxygenase YP_540023.1 999328 R 364106 CDS YP_540024.2 162138457 3994707 complement(1000470..1001429) 1 NC_007946.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1001429 ycbO 3994707 ycbO Escherichia coli UTI89 alkanesulfonate transporter substrate-binding subunit YP_540024.2 1000470 R 364106 CDS YP_540025.1 91210039 3994708 complement(1001422..1001997) 1 NC_007946.1 NAD(P)H-dependent FMN reductase 1001997 ycbP 3994708 ycbP Escherichia coli UTI89 NAD(P)H-dependent FMN reductase YP_540025.1 1001422 R 364106 CDS YP_540026.1 91210040 3994709 1002207..1003244 1 NC_007946.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1003244 pyrD 3994709 pyrD Escherichia coli UTI89 dihydroorotate dehydrogenase 2 YP_540026.1 1002207 D 364106 CDS YP_540027.1 91210041 3994710 1003382..1003960 1 NC_007946.1 hypothetical protein 1003960 ycbW 3994710 ycbW Escherichia coli UTI89 hypothetical protein YP_540027.1 1003382 D 364106 CDS YP_540028.1 91210042 3994711 complement(1003957..1005066) 1 NC_007946.1 hypothetical protein 1005066 ycbX 3994711 ycbX Escherichia coli UTI89 hypothetical protein YP_540028.1 1003957 R 364106 CDS YP_540029.1 91210043 3994712 1005164..1007272 1 NC_007946.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1007272 rlmL 3994712 rlmL Escherichia coli UTI89 23S rRNA m(2)G2445 methyltransferase YP_540029.1 1005164 D 364106 CDS YP_540030.1 91210044 3994713 1007284..1009191 1 NC_007946.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1009191 uup 3994713 uup Escherichia coli UTI89 ABC transporter ATPase YP_540030.1 1007284 D 364106 CDS YP_540031.1 91210045 3994714 1009321..1010574 1 NC_007946.1 paraquat-inducible protein A 1010574 pqiA 3994714 pqiA Escherichia coli UTI89 paraquat-inducible protein A YP_540031.1 1009321 D 364106 CDS YP_540032.1 91210046 3994715 1010519..1012219 1 NC_007946.1 paraquat-inducible protein B 1012219 pqiB 3994715 pqiB Escherichia coli UTI89 paraquat-inducible protein B YP_540032.1 1010519 D 364106 CDS YP_540033.1 91210047 3994716 1012216..1012779 1 NC_007946.1 hypothetical protein 1012779 ymbA 3994716 ymbA Escherichia coli UTI89 hypothetical protein YP_540033.1 1012216 D 364106 CDS YP_540034.1 91210048 3994717 1013035..1013202 1 NC_007946.1 ribosome modulation factor 1013202 rmf 3994717 rmf Escherichia coli UTI89 ribosome modulation factor YP_540034.1 1013035 D 364106 CDS YP_540035.2 162138456 3994718 complement(1013272..1013790) 1 NC_007946.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1013790 fabA 3994718 fabA Escherichia coli UTI89 3-hydroxydecanoyl-ACP dehydratase YP_540035.2 1013272 R 364106 CDS YP_540036.1 91210050 3994719 complement(1013859..1015619) 1 NC_007946.1 protease La-like protein 1015619 3994719 UTI89_C1020 Escherichia coli UTI89 protease La-like protein YP_540036.1 1013859 R 364106 CDS YP_540037.1 91210051 3994720 1015805..1016257 1 NC_007946.1 hypothetical protein 1016257 ycbG 3994720 ycbG Escherichia coli UTI89 hypothetical protein YP_540037.1 1015805 D 364106 CDS YP_540038.1 91210052 3994721 complement(1016335..1017462) 1 NC_007946.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein OmpA 1017462 ompA 3994721 ompA Escherichia coli UTI89 outer membrane protein OmpA YP_540038.1 1016335 R 364106 CDS YP_540039.1 91210053 3994722 1017529..1017747 1 NC_007946.1 hypothetical protein 1017747 3994722 UTI89_C1023 Escherichia coli UTI89 hypothetical protein YP_540039.1 1017529 D 364106 CDS YP_540040.1 91210054 3994723 complement(1017731..1018246) 1 NC_007946.1 SOS cell division inhibitor 1018246 sulA 3994723 sulA Escherichia coli UTI89 SOS cell division inhibitor YP_540040.1 1017731 R 364106 CDS YP_540041.1 91210055 3994724 1018459..1019088 1 NC_007946.1 hypothetical protein 1019088 yccR 3994724 yccR Escherichia coli UTI89 hypothetical protein YP_540041.1 1018459 D 364106 CDS YP_540042.1 91210056 3994725 complement(1019051..1021213) 1 NC_007946.1 hypothetical protein 1021213 yccS 3994725 yccS Escherichia coli UTI89 hypothetical protein YP_540042.1 1019051 R 364106 CDS YP_540043.1 91210057 3993121 complement(1021223..1021669) 1 NC_007946.1 hypothetical protein 1021669 yccF 3993121 yccF Escherichia coli UTI89 hypothetical protein YP_540043.1 1021223 R 364106 CDS YP_540044.2 162138455 3993122 1021792..1023846 1 NC_007946.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1023846 helD 3993122 helD Escherichia coli UTI89 DNA helicase IV YP_540044.2 1021792 D 364106 CDS YP_540045.1 91210059 3993123 complement(1023878..1024345) 1 NC_007946.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1024345 mgsA 3993123 mgsA Escherichia coli UTI89 methylglyoxal synthase YP_540045.1 1023878 R 364106 CDS YP_540046.1 91210060 3993124 complement(1024432..1025094) 1 NC_007946.1 hypothetical protein 1025094 yccT 3993124 yccT Escherichia coli UTI89 hypothetical protein YP_540046.1 1024432 R 364106 CDS YP_540047.1 91210061 3993125 1025186..1025680 1 NC_007946.1 hypothetical protein 1025680 3993125 UTI89_C1031 Escherichia coli UTI89 hypothetical protein YP_540047.1 1025186 D 364106 CDS YP_540048.1 91210062 3993126 1025649..1026044 1 NC_007946.1 hypothetical protein 1026044 3993126 UTI89_C1032 Escherichia coli UTI89 hypothetical protein YP_540048.1 1025649 D 364106 CDS YP_540049.1 91210063 3993127 complement(1025725..1026093) 1 NC_007946.1 heat shock protein HspQ 1026093 yccV 3993127 yccV Escherichia coli UTI89 heat shock protein HspQ YP_540049.1 1025725 R 364106 CDS YP_540050.1 91210064 3993128 complement(1026100..1027290) 1 NC_007946.1 hypothetical protein 1027290 yccW 3993128 yccW Escherichia coli UTI89 hypothetical protein YP_540050.1 1026100 R 364106 CDS YP_540051.1 91210065 3993129 1027265..1027663 1 NC_007946.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1027663 3993129 UTI89_C1035 Escherichia coli UTI89 acylphosphatase YP_540051.1 1027265 D 364106 CDS YP_540052.1 91210066 3993130 complement(1027660..1027989) 1 NC_007946.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1027989 yccK 3993130 yccK Escherichia coli UTI89 sulfur transfer protein TusE YP_540052.1 1027660 R 364106 CDS YP_540053.1 91210067 3993131 complement(1028081..1028740) 1 NC_007946.1 hypothetical protein 1028740 yccA 3993131 yccA Escherichia coli UTI89 hypothetical protein YP_540053.1 1028081 R 364106 CDS YP_540055.1 91210069 3993134 1029434..1030579 1 NC_007946.1 hydrogenase-1 small chain 1030579 hyaA 3993134 hyaA Escherichia coli UTI89 hydrogenase-1 small chain YP_540055.1 1029434 D 364106 CDS YP_540056.1 91210070 3993135 1030576..1032369 1 NC_007946.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1032369 hyaB 3993135 hyaB Escherichia coli UTI89 hydrogenase 1 large subunit YP_540056.1 1030576 D 364106 CDS YP_540057.1 91210071 3993136 1032388..1033095 1 NC_007946.1 hydrogenase 1 b-type cytochrome subunit 1033095 hyaC 3993136 hyaC Escherichia coli UTI89 hydrogenase 1 b-type cytochrome subunit YP_540057.1 1032388 D 364106 CDS YP_540058.1 91210072 3993137 1033092..1033679 1 NC_007946.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1033679 hyaD 3993137 hyaD Escherichia coli UTI89 hydrogenase 1 maturation protease YP_540058.1 1033092 D 364106 CDS YP_540059.1 91210073 3993138 1033676..1034074 1 NC_007946.1 involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1034074 hyaE 3993138 hyaE Escherichia coli UTI89 hydrogenase-1 operon protein HyaE YP_540059.1 1033676 D 364106 CDS YP_540060.1 91210074 3994627 1034071..1034928 1 NC_007946.1 hydrogenase-1 operon protein HyaF 1034928 hyaF 3994627 hyaF Escherichia coli UTI89 hydrogenase-1 operon protein HyaF YP_540060.1 1034071 D 364106 CDS YP_540061.1 91210075 3994628 1035062..1036606 1 NC_007946.1 third cytochrome oxidase subunit I 1036606 appC 3994628 appC Escherichia coli UTI89 third cytochrome oxidase subunit I YP_540061.1 1035062 D 364106 CDS YP_540062.1 91210076 3994629 1036618..1037754 1 NC_007946.1 third cytochrome oxidase subunit II 1037754 appB 3994629 appB Escherichia coli UTI89 third cytochrome oxidase subunit II YP_540062.1 1036618 D 364106 CDS YP_540063.1 91210077 3994630 1037767..1037859 1 NC_007946.1 expressed during stationary phase; hypothetical protein 1037859 yccB 3994630 yccB Escherichia coli UTI89 hypothetical protein YP_540063.1 1037767 D 364106 CDS YP_540064.1 91210078 3994631 1037909..1039249 1 NC_007946.1 phosphoanhydride phosphorylase 1039249 appA 3994631 appA Escherichia coli UTI89 phosphoanhydride phosphorylase YP_540064.1 1037909 D 364106 CDS YP_540065.1 91210079 3994632 complement(1039237..1039449) 1 NC_007946.1 cold shock-like protein H 1039449 cspH 3994632 cspH Escherichia coli UTI89 cold shock-like protein H YP_540065.1 1039237 R 364106 CDS YP_540066.1 91210080 3994633 1039735..1039947 1 NC_007946.1 cold shock protein CspG 1039947 cspG 3994633 cspG Escherichia coli UTI89 cold shock protein CspG YP_540066.1 1039735 D 364106 CDS YP_540067.1 91210081 3994634 1040088..1040351 1 NC_007946.1 cold shock gene 1040351 sfa 3994634 sfa Escherichia coli UTI89 cold shock gene YP_540067.1 1040088 D 364106 CDS YP_540068.1 91210082 3994635 1040341..1040514 1 NC_007946.1 protein that affects unsaturated fatty acid abundance 1040514 gnsB 3994635 gnsB Escherichia coli UTI89 protein that affects unsaturated fatty acid abundance YP_540068.1 1040341 D 364106 CDS YP_540069.1 91210083 3994636 complement(1040356..1040529) 1 NC_007946.1 hypothetical protein 1040529 3994636 UTI89_C1054 Escherichia coli UTI89 hypothetical protein YP_540069.1 1040356 R 364106 CDS YP_540070.1 91210084 3994637 complement(1040563..1041636) 1 NC_007946.1 electron transport protein YccM 1041636 yccM 3994637 yccM Escherichia coli UTI89 electron transport protein YccM YP_540070.1 1040563 R 364106 CDS YP_540071.1 91210085 3994638 complement(1041719..1044451) 1 NC_007946.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1044451 torS 3994638 torS Escherichia coli UTI89 hybrid sensory histidine kinase TorS YP_540071.1 1041719 R 364106 CDS YP_540073.1 91210087 3994640 1044534..1045562 1 NC_007946.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1045562 torT 3994640 torT Escherichia coli UTI89 TMAO reductase system periplasmic protein TorT YP_540073.1 1044534 D 364106 CDS YP_540074.1 91210088 3994641 complement(1045535..1046227) 1 NC_007946.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1046227 torR 3994641 torR Escherichia coli UTI89 DNA-binding transcriptional regulator TorR YP_540074.1 1045535 R 364106 CDS YP_540075.1 91210089 3994642 1046319..1047539 1 NC_007946.1 cytochrome c-type protein TorC 1047539 torC 3994642 torC Escherichia coli UTI89 cytochrome c-type protein TorC YP_540075.1 1046319 D 364106 CDS YP_540076.1 91210090 3994643 1047539..1050085 1 NC_007946.1 trimethylamine-N-oxide reductase 1 1050085 torA 3994643 torA Escherichia coli UTI89 trimethylamine-N-oxide reductase 1 YP_540076.1 1047539 D 364106 CDS YP_540077.1 91210091 3994644 1050049..1050681 1 NC_007946.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1050681 torD 3994644 torD Escherichia coli UTI89 chaperone protein TorD YP_540077.1 1050049 D 364106 CDS YP_540078.1 91210092 3994645 complement(1051037..1051342) 1 NC_007946.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1051342 yccD 3994645 yccD Escherichia coli UTI89 chaperone-modulator protein CbpM YP_540078.1 1051037 R 364106 CDS YP_540079.1 91210093 3994646 complement(1051342..1052262) 1 NC_007946.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1052262 cbpA 3994646 cbpA Escherichia coli UTI89 curved DNA-binding protein CbpA YP_540079.1 1051342 R 364106 CDS YP_540080.1 91210094 3989940 1052797..1054038 1 NC_007946.1 glucose-1-phosphatase/inositol phosphatase 1054038 agp 3989940 agp Escherichia coli UTI89 glucose-1-phosphatase/inositol phosphatase YP_540080.1 1052797 D 364106 CDS YP_540081.1 91210095 3989941 complement(1054076..1054303) 1 NC_007946.1 hypothetical protein 1054303 yccJ 3989941 yccJ Escherichia coli UTI89 hypothetical protein YP_540081.1 1054076 R 364106 CDS YP_540082.1 91210096 3989942 complement(1054324..1054920) 1 NC_007946.1 stationary phase that binds TrpR repressor; TrpR binding protein WrbA 1054920 wrbA 3989942 wrbA Escherichia coli UTI89 TrpR binding protein WrbA YP_540082.1 1054324 R 364106 CDS YP_540083.1 91210097 3989943 1055324..1055482 1 NC_007946.1 hypothetical protein 1055482 3989943 UTI89_C1068 Escherichia coli UTI89 hypothetical protein YP_540083.1 1055324 D 364106 CDS YP_540084.1 91210098 3989944 1055479..1055616 1 NC_007946.1 hypothetical protein 1055616 3989944 UTI89_C1069 Escherichia coli UTI89 hypothetical protein YP_540084.1 1055479 D 364106 CDS YP_540085.1 91210099 3989945 complement(1056792..1057367) 1 NC_007946.1 4-hydroxyphenylacetate 3-monooxygenase small chain 1057367 nmoB 3989945 nmoB Escherichia coli UTI89 4-hydroxyphenylacetate 3-monooxygenase small chain YP_540085.1 1056792 R 364106 CDS YP_540086.1 91210100 3989946 complement(1057297..1057887) 1 NC_007946.1 hypothetical protein 1057887 3989946 UTI89_C1071 Escherichia coli UTI89 hypothetical protein YP_540086.1 1057297 R 364106 CDS YP_540087.1 91210101 3989947 complement(1057897..1058724) 1 NC_007946.1 hypothetical protein 1058724 ycdJ 3989947 ycdJ Escherichia coli UTI89 hypothetical protein YP_540087.1 1057897 R 364106 CDS YP_540088.1 91210102 3989948 complement(1058705..1059091) 1 NC_007946.1 hypothetical protein 1059091 ycdK 3989948 ycdK Escherichia coli UTI89 hypothetical protein YP_540088.1 1058705 R 364106 CDS YP_540089.1 91210103 3989949 complement(1059103..1059837) 1 NC_007946.1 isochorismatase YcdL 1059837 ycdL 3989949 ycdL Escherichia coli UTI89 isochorismatase YcdL YP_540089.1 1059103 R 364106 CDS YP_540090.1 91210104 3989950 complement(1059795..1060976) 1 NC_007946.1 monooxygenase YcdM 1060976 ycdM 3989950 ycdM Escherichia coli UTI89 monooxygenase YcdM YP_540090.1 1059795 R 364106 CDS YP_540091.1 91210105 3989951 1061146..1061811 1 NC_007946.1 transcriptional regulator YcdC 1061811 ycdC 3989951 ycdC Escherichia coli UTI89 transcriptional regulator YcdC YP_540091.1 1061146 D 364106 CDS YP_540092.2 162138454 3989952 complement(1061851..1065813) 1 NC_007946.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1065813 putA 3989952 putA Escherichia coli UTI89 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_540092.2 1061851 R 364106 CDS YP_540093.1 91210107 3989953 1065868..1066077 1 NC_007946.1 hypothetical protein 1066077 3989953 UTI89_C1078 Escherichia coli UTI89 hypothetical protein YP_540093.1 1065868 D 364106 CDS YP_540094.1 91210108 3989954 1066236..1067744 1 NC_007946.1 sodium/proline symporter 1067744 putP 3989954 putP Escherichia coli UTI89 sodium/proline symporter YP_540094.1 1066236 D 364106 CDS YP_540095.1 91210109 3989955 1067955..1068794 1 NC_007946.1 hypothetical protein 1068794 3989955 UTI89_C1080 Escherichia coli UTI89 hypothetical protein YP_540095.1 1067955 D 364106 CDS YP_540096.1 91210110 3989956 1068852..1069979 1 NC_007946.1 hypothetical protein 1069979 ycdO 3989956 ycdO Escherichia coli UTI89 hypothetical protein YP_540096.1 1068852 D 364106 CDS YP_540097.1 91210111 3989957 1069985..1071256 1 NC_007946.1 hypothetical protein 1071256 ycdB 3989957 ycdB Escherichia coli UTI89 hypothetical protein YP_540097.1 1069985 D 364106 CDS YP_540098.1 91210112 3989958 1071747..1072670 1 NC_007946.1 hypothetical protein 1072670 phoH 3989958 phoH Escherichia coli UTI89 hypothetical protein YP_540098.1 1071747 D 364106 CDS YP_540099.1 91210113 3991931 complement(1072720..1073133) 1 NC_007946.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1073133 pgaD 3991931 pgaD Escherichia coli UTI89 PGA biosynthesis protein YP_540099.1 1072720 R 364106 CDS YP_540100.1 91210114 3991932 complement(1073135..1074460) 1 NC_007946.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1074460 ycdQ 3991932 ycdQ Escherichia coli UTI89 N-glycosyltransferase YP_540100.1 1073135 R 364106 CDS YP_540101.1 91210115 3991933 complement(1074453..1076471) 1 NC_007946.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1076471 pgaB 3991933 pgaB Escherichia coli UTI89 outer membrane N-deacetylase YP_540101.1 1074453 R 364106 CDS YP_540102.1 91210116 3991934 complement(1076480..1078903) 1 NC_007946.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1078903 pgaA 3991934 pgaA Escherichia coli UTI89 outer membrane protein PgaA YP_540102.1 1076480 R 364106 CDS YP_540103.1 91210117 3991935 1079368..1080858 1 NC_007946.1 hypothetical protein 1080858 ycdT 3991935 ycdT Escherichia coli UTI89 hypothetical protein YP_540103.1 1079368 D 364106 CDS YP_540104.1 91210118 3991936 1081137..1082339 1 NC_007946.1 P4 family integrase 1082339 3991936 UTI89_C1089 Escherichia coli UTI89 P4 family integrase YP_540104.1 1081137 D 364106 CDS YP_540105.1 91210119 3991937 complement(1082526..1084343) 1 NC_007946.1 hypothetical protein 1084343 3991937 UTI89_C1090 Escherichia coli UTI89 hypothetical protein YP_540105.1 1082526 R 364106 CDS YP_540106.1 91210120 3991938 1084628..1084792 1 NC_007946.1 hypothetical protein 1084792 3991938 UTI89_C1091 Escherichia coli UTI89 hypothetical protein YP_540106.1 1084628 D 364106 CDS YP_540107.1 91210121 3991939 1084840..1085304 1 NC_007946.1 transposase 1085304 3991939 UTI89_C1092 Escherichia coli UTI89 transposase YP_540107.1 1084840 D 364106 CDS YP_540108.1 91210122 3991940 1085457..1085753 1 NC_007946.1 prophage regulatory protein 1085753 3991940 UTI89_C1093 Escherichia coli UTI89 prophage regulatory protein YP_540108.1 1085457 D 364106 CDS YP_540109.1 91210123 3991941 1086378..1087829 1 NC_007946.1 hypothetical protein 1087829 yfjI 3991941 yfjI Escherichia coli UTI89 hypothetical protein YP_540109.1 1086378 D 364106 CDS YP_540110.1 91210124 3991942 1088785..1089378 1 NC_007946.1 hypothetical protein 1089378 3991942 UTI89_C1095 Escherichia coli UTI89 hypothetical protein YP_540110.1 1088785 D 364106 CDS YP_540111.1 91210125 3991943 complement(1089477..1089734) 1 NC_007946.1 hypothetical protein 1089734 3991943 UTI89_C1096 Escherichia coli UTI89 hypothetical protein YP_540111.1 1089477 R 364106 CDS YP_540112.1 91210126 3991944 1089480..1089686 1 NC_007946.1 hypothetical protein 1089686 3991944 UTI89_C1097 Escherichia coli UTI89 hypothetical protein YP_540112.1 1089480 D 364106 CDS YP_540113.1 91210127 3991945 complement(1089855..1091855) 1 NC_007946.1 hypothetical protein 1091855 3991945 UTI89_C1098 Escherichia coli UTI89 hypothetical protein YP_540113.1 1089855 R 364106 CDS YP_540114.1 91210128 3991946 complement(1091770..1092936) 1 NC_007946.1 aminotransferase 1092936 3991946 UTI89_C1099 Escherichia coli UTI89 aminotransferase YP_540114.1 1091770 R 364106 CDS YP_540115.1 91210129 3991947 complement(1093070..1093336) 1 NC_007946.1 tagatose-bisphosphate aldolase 2 1093336 3991947 UTI89_C1100 Escherichia coli UTI89 tagatose-bisphosphate aldolase 2 YP_540115.1 1093070 R 364106 CDS YP_540116.1 91210130 3991948 complement(1093358..1093981) 1 NC_007946.1 hypothetical protein 1093981 3991948 UTI89_C1101 Escherichia coli UTI89 hypothetical protein YP_540116.1 1093358 R 364106 CDS YP_540117.1 91210131 3991949 complement(1094034..1094297) 1 NC_007946.1 hypothetical protein 1094297 3991949 UTI89_C1102 Escherichia coli UTI89 hypothetical protein YP_540117.1 1094034 R 364106 CDS YP_540118.1 91210132 3991950 1095846..1096370 1 NC_007946.1 hypothetical protein 1096370 3991950 UTI89_C1103 Escherichia coli UTI89 hypothetical protein YP_540118.1 1095846 D 364106 CDS YP_540119.1 91210133 3991350 1096409..1096921 1 NC_007946.1 hypothetical protein 1096921 3991350 UTI89_C1104 Escherichia coli UTI89 hypothetical protein YP_540119.1 1096409 D 364106 CDS YP_540120.1 91210134 3991351 complement(1096433..1096609) 1 NC_007946.1 hypothetical protein 1096609 3991351 UTI89_C1105 Escherichia coli UTI89 hypothetical protein YP_540120.1 1096433 R 364106 CDS YP_540121.1 91210135 3991352 1097163..1097732 1 NC_007946.1 hypothetical protein 1097732 3991352 UTI89_C1106 Escherichia coli UTI89 hypothetical protein YP_540121.1 1097163 D 364106 CDS YP_540122.1 91210136 3991353 complement(1098007..1098291) 1 NC_007946.1 S fimbrial switch regulatory protein 1098291 sfaC 3991353 sfaC Escherichia coli UTI89 S fimbrial switch regulatory protein YP_540122.1 1098007 R 364106 CDS YP_540123.1 91210137 3991354 1098647..1098976 1 NC_007946.1 S fimbrial switch regulatory protein 1098976 sfaB 3991354 sfaB Escherichia coli UTI89 S fimbrial switch regulatory protein YP_540123.1 1098647 D 364106 CDS YP_540124.1 91210138 3991355 1099351..1099896 1 NC_007946.1 S fimbriae major subunit SfaA 1099896 sfaA 3991355 sfaA Escherichia coli UTI89 S fimbriae major subunit SfaA YP_540124.1 1099351 D 364106 CDS YP_540125.1 91210139 3991356 1099958..1100506 1 NC_007946.1 S fimbriae minor subunit SfaD 1100506 sfaD 3991356 sfaD Escherichia coli UTI89 S fimbriae minor subunit SfaD YP_540125.1 1099958 D 364106 CDS YP_540126.1 91210140 3991357 1100547..1101242 1 NC_007946.1 S fimbriae periplasmic chaperone SfaE 1101242 sfaE 3991357 sfaE Escherichia coli UTI89 S fimbriae periplasmic chaperone SfaE YP_540126.1 1100547 D 364106 CDS YP_540127.1 91210141 3991358 1101264..1103942 1 NC_007946.1 S fimbriae outer membrane usher 1103942 sfaF 3991358 sfaF Escherichia coli UTI89 S fimbriae outer membrane usher YP_540127.1 1101264 D 364106 CDS YP_540128.1 91210142 3991359 1103955..1104482 1 NC_007946.1 S fimbriae minor subunit SfaG 1104482 sfaG 3991359 sfaG Escherichia coli UTI89 S fimbriae minor subunit SfaG YP_540128.1 1103955 D 364106 CDS YP_540129.1 91210143 3991360 1104504..1104995 1 NC_007946.1 S fimbriae minor subunit SfaS 1104995 sfaS 3991360 sfaS Escherichia coli UTI89 S fimbriae minor subunit SfaS YP_540129.1 1104504 D 364106 CDS YP_540130.1 91210144 3991361 1104988..1105956 1 NC_007946.1 S fimbriae minor subunit SfaH 1105956 sfaH 3991361 sfaH Escherichia coli UTI89 S fimbriae minor subunit SfaH YP_540130.1 1104988 D 364106 CDS YP_540131.1 91210145 3991362 1106260..1107000 1 NC_007946.1 hypothetical protein 1107000 3991362 UTI89_C1116 Escherichia coli UTI89 hypothetical protein YP_540131.1 1106260 D 364106 CDS YP_540132.1 91210146 3991363 1107147..1107698 1 NC_007946.1 regulatory protein 1107698 focX 3991363 focX Escherichia coli UTI89 regulatory protein YP_540132.1 1107147 D 364106 CDS YP_540133.1 91210147 3991364 1108192..1110369 1 NC_007946.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 1110369 iroN 3991364 iroN Escherichia coli UTI89 outer membrane receptor FepA YP_540133.1 1108192 D 364106 CDS YP_540134.1 91210148 3991365 complement(1110414..1111370) 1 NC_007946.1 IroE protein 1111370 iroE 3991365 iroE Escherichia coli UTI89 IroE protein YP_540134.1 1110414 R 364106 CDS YP_540135.1 91210149 3991366 complement(1111455..1112684) 1 NC_007946.1 IroD protein 1112684 iroD 3991366 iroD Escherichia coli UTI89 IroD protein YP_540135.1 1111455 R 364106 CDS YP_540136.1 91210150 3991367 complement(1112788..1116573) 1 NC_007946.1 IroC protein 1116573 iroC 3991367 iroC Escherichia coli UTI89 IroC protein YP_540136.1 1112788 R 364106 CDS YP_540137.1 91210151 3991368 complement(1116587..1117750) 1 NC_007946.1 glucosyltransferase 1117750 iroB 3991368 iroB Escherichia coli UTI89 glucosyltransferase YP_540137.1 1116587 R 364106 CDS YP_540138.1 91210152 3993370 1118244..1118558 1 NC_007946.1 hypothetical protein 1118558 3993370 UTI89_C1123 Escherichia coli UTI89 hypothetical protein YP_540138.1 1118244 D 364106 CDS YP_540139.1 91210153 3993371 complement(1118597..1118959) 1 NC_007946.1 hypothetical protein 1118959 3993371 UTI89_C1124 Escherichia coli UTI89 hypothetical protein YP_540139.1 1118597 R 364106 CDS YP_540140.1 91210154 3993372 1119826..1120260 1 NC_007946.1 hypothetical protein 1120260 3993372 UTI89_C1125 Escherichia coli UTI89 hypothetical protein YP_540140.1 1119826 D 364106 CDS YP_540141.1 91210155 3993374 complement(1120823..1121281) 1 NC_007946.1 transposase 1121281 3993374 UTI89_C1127 Escherichia coli UTI89 transposase YP_540141.1 1120823 R 364106 CDS YP_540142.1 91210156 3993375 complement(1121293..1122186) 1 NC_007946.1 hypothetical protein 1122186 3993375 UTI89_C1128 Escherichia coli UTI89 hypothetical protein YP_540142.1 1121293 R 364106 CDS YP_540143.1 91210157 3993376 1122532..1124502 1 NC_007946.1 outer membrane heme/hemoglobin receptor 1124502 3993376 UTI89_C1129 Escherichia coli UTI89 outer membrane heme/hemoglobin receptor YP_540143.1 1122532 D 364106 CDS YP_540144.1 91210158 3993377 1124521..1125312 1 NC_007946.1 hypothetical protein 1125312 3993377 UTI89_C1130 Escherichia coli UTI89 hypothetical protein YP_540144.1 1124521 D 364106 CDS YP_540145.1 91210159 3993378 1125513..1126775 1 NC_007946.1 hypothetical protein 1126775 3993378 UTI89_C1131 Escherichia coli UTI89 hypothetical protein YP_540145.1 1125513 D 364106 CDS YP_540146.1 91210160 3993379 complement(1126882..1127064) 1 NC_007946.1 hypothetical protein 1127064 3993379 UTI89_C1132 Escherichia coli UTI89 hypothetical protein YP_540146.1 1126882 R 364106 CDS YP_540147.1 91210161 3993380 1127725..1128861 1 NC_007946.1 hypothetical protein 1128861 3993380 UTI89_C1133 Escherichia coli UTI89 hypothetical protein YP_540147.1 1127725 D 364106 CDS YP_540148.1 91210162 3993381 complement(1129663..1129989) 1 NC_007946.1 hypothetical protein 1129989 3993381 UTI89_C1134 Escherichia coli UTI89 hypothetical protein YP_540148.1 1129663 R 364106 CDS YP_540149.1 91210163 3993382 complement(1130377..1130736) 1 NC_007946.1 hypothetical protein 1130736 3993382 UTI89_C1135 Escherichia coli UTI89 hypothetical protein YP_540149.1 1130377 R 364106 CDS YP_540150.1 91210164 3993383 complement(1130945..1131274) 1 NC_007946.1 hypothetical protein 1131274 3993383 UTI89_C1136 Escherichia coli UTI89 hypothetical protein YP_540150.1 1130945 R 364106 CDS YP_540151.1 91210165 3993384 complement(1131288..1131593) 1 NC_007946.1 hypothetical protein 1131593 3993384 UTI89_C1137 Escherichia coli UTI89 hypothetical protein YP_540151.1 1131288 R 364106 CDS YP_540152.1 91210166 3993385 1132408..1133280 1 NC_007946.1 hypothetical protein 1133280 3993385 UTI89_C1138 Escherichia coli UTI89 hypothetical protein YP_540152.1 1132408 D 364106 CDS YP_540153.1 91210167 3993386 1133653..1136499 1 NC_007946.1 autotransporter 1136499 3993386 UTI89_C1139 Escherichia coli UTI89 autotransporter YP_540153.1 1133653 D 364106 CDS YP_540154.1 91210168 3993387 1136830..1137651 1 NC_007946.1 hypothetical protein 1137651 yafZ1 3993387 yafZ1 Escherichia coli UTI89 hypothetical protein YP_540154.1 1136830 D 364106 CDS YP_540155.1 91210169 3993388 complement(1136836..1137693) 1 NC_007946.1 hypothetical protein 1137693 3993388 UTI89_C1141 Escherichia coli UTI89 hypothetical protein YP_540155.1 1136836 R 364106 CDS YP_540156.1 91210170 3994156 1137672..1137896 1 NC_007946.1 hypothetical protein 1137896 3994156 UTI89_C1142 Escherichia coli UTI89 hypothetical protein YP_540156.1 1137672 D 364106 CDS YP_540157.1 91210171 3994157 1137918..1138463 1 NC_007946.1 hypothetical protein 1138463 yafX1 3994157 yafX1 Escherichia coli UTI89 hypothetical protein YP_540157.1 1137918 D 364106 CDS YP_540158.1 91210172 3994158 complement(1137984..1138943) 1 NC_007946.1 hypothetical protein 1138943 3994158 UTI89_C1144 Escherichia coli UTI89 hypothetical protein YP_540158.1 1137984 R 364106 CDS YP_540159.1 91210173 3994159 1138479..1138955 1 NC_007946.1 radC-like protein YeeS 1138955 yeeS3 3994159 yeeS3 Escherichia coli UTI89 radC-like protein YeeS YP_540159.1 1138479 D 364106 CDS YP_540160.1 91210174 3994160 1139018..1139239 1 NC_007946.1 hypothetical protein 1139239 yeeT3 3994160 yeeT3 Escherichia coli UTI89 hypothetical protein YP_540160.1 1139018 D 364106 CDS YP_540161.1 91210175 3994161 1139258..1139902 1 NC_007946.1 hypothetical protein 1139902 3994161 UTI89_C1147 Escherichia coli UTI89 hypothetical protein YP_540161.1 1139258 D 364106 CDS YP_540162.1 91210176 3994162 1139862..1140329 1 NC_007946.1 intergenic-region protein 1140329 3994162 UTI89_C1148 Escherichia coli UTI89 intergenic-region protein YP_540162.1 1139862 D 364106 CDS YP_540163.1 91210177 3994163 1140376..1140750 1 NC_007946.1 hypothetical protein 1140750 3994163 UTI89_C1149 Escherichia coli UTI89 hypothetical protein YP_540163.1 1140376 D 364106 CDS YP_540164.1 91210178 3994164 1140750..1141238 1 NC_007946.1 hypothetical protein 1141238 3994164 UTI89_C1150 Escherichia coli UTI89 hypothetical protein YP_540164.1 1140750 D 364106 CDS YP_540165.1 91210179 3994165 1141250..1141447 1 NC_007946.1 hypothetical protein 1141447 3994165 UTI89_C1151 Escherichia coli UTI89 hypothetical protein YP_540165.1 1141250 D 364106 CDS YP_540166.1 91210180 3994166 1141540..1142382 1 NC_007946.1 hypothetical protein 1142382 3994166 UTI89_C1152 Escherichia coli UTI89 hypothetical protein YP_540166.1 1141540 D 364106 CDS YP_540167.1 91210181 3994168 1142814..1143791 1 NC_007946.1 dehydrogenase 1143791 ycdW 3994168 ycdW Escherichia coli UTI89 dehydrogenase YP_540167.1 1142814 D 364106 CDS YP_540168.1 91210182 3994169 1143846..1144583 1 NC_007946.1 hydrolase 1144583 ycdX 3994169 ycdX Escherichia coli UTI89 hydrolase YP_540168.1 1143846 D 364106 CDS YP_540169.1 91210183 3994170 1144607..1145161 1 NC_007946.1 hypothetical protein 1145161 ycdY 3994170 ycdY Escherichia coli UTI89 hypothetical protein YP_540169.1 1144607 D 364106 CDS YP_540170.1 91210184 3994171 1145215..1145754 1 NC_007946.1 hypothetical protein 1145754 ycdZ 3994171 ycdZ Escherichia coli UTI89 hypothetical protein YP_540170.1 1145215 D 364106 CDS YP_540171.1 91210185 3994172 complement(1145819..1146652) 1 NC_007946.1 curli production protein CsgG 1146652 csgG 3994172 csgG Escherichia coli UTI89 curli production protein CsgG YP_540171.1 1145819 R 364106 CDS YP_540172.1 91210186 3994173 complement(1146679..1147095) 1 NC_007946.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1147095 csgF 3994173 csgF Escherichia coli UTI89 curli assembly protein CsgF YP_540172.1 1146679 R 364106 CDS YP_540173.1 91210187 3993926 complement(1147120..1147509) 1 NC_007946.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1147509 csgE 3993926 csgE Escherichia coli UTI89 curli assembly protein CsgE YP_540173.1 1147120 R 364106 CDS YP_540174.1 91210188 3993927 complement(1147514..1148164) 1 NC_007946.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1148164 csgD 3993927 csgD Escherichia coli UTI89 DNA-binding transcriptional regulator CsgD YP_540174.1 1147514 R 364106 CDS YP_540175.1 91210189 3993928 1148138..1148278 1 NC_007946.1 hypothetical protein 1148278 3993928 UTI89_C1162 Escherichia coli UTI89 hypothetical protein YP_540175.1 1148138 D 364106 CDS YP_540176.1 91210190 3993929 complement(1148689..1148823) 1 NC_007946.1 hypothetical protein 1148823 3993929 UTI89_C1163 Escherichia coli UTI89 hypothetical protein YP_540176.1 1148689 R 364106 CDS YP_540177.1 91210191 3993930 1148890..1149372 1 NC_007946.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1149372 csgB 3993930 csgB Escherichia coli UTI89 curlin minor subunit YP_540177.1 1148890 D 364106 CDS YP_540178.1 91210192 3993931 1149413..1149868 1 NC_007946.1 cryptic curlin major subunit 1149868 csgA 3993931 csgA Escherichia coli UTI89 cryptic curlin major subunit YP_540178.1 1149413 D 364106 CDS YP_540179.1 91210193 3993932 1149927..1150259 1 NC_007946.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1150259 csgC 3993932 csgC Escherichia coli UTI89 autoagglutination protein YP_540179.1 1149927 D 364106 CDS YP_540180.1 91210194 3993933 1150380..1150691 1 NC_007946.1 hypothetical protein 1150691 3993933 UTI89_C1167 Escherichia coli UTI89 hypothetical protein YP_540180.1 1150380 D 364106 CDS YP_540181.1 91210195 3993934 1150786..1151319 1 NC_007946.1 hypothetical protein 1151319 ymdB 3993934 ymdB Escherichia coli UTI89 hypothetical protein YP_540181.1 1150786 D 364106 CDS YP_540182.1 91210196 3993935 1151261..1152742 1 NC_007946.1 synthase 1152742 ymdC 3993935 ymdC Escherichia coli UTI89 synthase YP_540182.1 1151261 D 364106 CDS YP_540183.1 91210197 3993936 complement(1152750..1153907) 1 NC_007946.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1153907 mdoC 3993936 mdoC Escherichia coli UTI89 glucans biosynthesis protein YP_540183.1 1152750 R 364106 CDS YP_540184.1 91210198 3993937 complement(1153952..1154095) 1 NC_007946.1 hypothetical protein 1154095 3993937 UTI89_C1171 Escherichia coli UTI89 hypothetical protein YP_540184.1 1153952 R 364106 CDS YP_540185.1 91210199 3993938 1154283..1155836 1 NC_007946.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1155836 mdoG 3993938 mdoG Escherichia coli UTI89 glucan biosynthesis protein G YP_540185.1 1154283 D 364106 CDS YP_540186.1 91210200 3993939 1155799..1158372 1 NC_007946.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1158372 mdoH 3993939 mdoH Escherichia coli UTI89 glucosyltransferase MdoH YP_540186.1 1155799 D 364106 CDS YP_540187.1 91210201 3993940 1158381..1158596 1 NC_007946.1 hypothetical protein 1158596 3993940 UTI89_C1174 Escherichia coli UTI89 hypothetical protein YP_540187.1 1158381 D 364106 CDS YP_540188.1 91210202 3993941 1158544..1158771 1 NC_007946.1 hypothetical protein 1158771 yceK 3993941 yceK Escherichia coli UTI89 hypothetical protein YP_540188.1 1158544 D 364106 CDS YP_540189.1 91210203 3993942 complement(1158772..1159149) 1 NC_007946.1 hypothetical protein 1159149 msyB 3993942 msyB Escherichia coli UTI89 hypothetical protein YP_540189.1 1158772 R 364106 CDS YP_540190.1 91210204 3993943 complement(1159229..1160455) 1 NC_007946.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1160455 yceE 3993943 yceE Escherichia coli UTI89 drug efflux system protein MdtG YP_540190.1 1159229 R 364106 CDS YP_540191.1 91210205 3993944 complement(1160627..1161610) 1 NC_007946.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1161610 htrB 3993944 htrB Escherichia coli UTI89 lipid A biosynthesis lauroyl acyltransferase YP_540191.1 1160627 R 364106 CDS YP_540192.1 91210206 3993945 1161718..1162824 1 NC_007946.1 hypothetical protein 1162824 yceA 3993945 yceA Escherichia coli UTI89 hypothetical protein YP_540192.1 1161718 D 364106 CDS YP_540193.1 91210207 3994726 complement(1162866..1163441) 1 NC_007946.1 hypothetical protein 1163441 yceI 3994726 yceI Escherichia coli UTI89 hypothetical protein YP_540193.1 1162866 R 364106 CDS YP_540194.1 91210208 3994727 complement(1163445..1164023) 1 NC_007946.1 cytochrome b561-like protein 2 1164023 3994727 UTI89_C1181 Escherichia coli UTI89 cytochrome b561-like protein 2 YP_540194.1 1163445 R 364106 CDS YP_540195.1 91210209 3994728 1164001..1164147 1 NC_007946.1 hypothetical protein 1164147 3994728 UTI89_C1182 Escherichia coli UTI89 hypothetical protein YP_540195.1 1164001 D 364106 CDS YP_540196.1 91210210 3994729 complement(1164272..1164412) 1 NC_007946.1 hypothetical protein 1164412 yceO 3994729 yceO Escherichia coli UTI89 hypothetical protein YP_540196.1 1164272 R 364106 CDS YP_540197.1 91210211 3994730 complement(1164433..1165551) 1 NC_007946.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1165551 solA 3994730 solA Escherichia coli UTI89 N-methyltryptophan oxidase YP_540197.1 1164433 R 364106 CDS YP_540198.2 162138453 3994731 complement(1165666..1165920) 1 NC_007946.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1165920 bssS 3994731 bssS Escherichia coli UTI89 biofilm formation regulatory protein BssS YP_540198.2 1165666 R 364106 CDS YP_540199.1 91210213 3994732 complement(1166210..1166512) 1 NC_007946.1 DNA damage-inducible protein I 1166512 3994732 UTI89_C1186 Escherichia coli UTI89 DNA damage-inducible protein I YP_540199.1 1166210 R 364106 CDS YP_540200.1 91210214 3994733 complement(1166529..1167575) 1 NC_007946.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1167575 pyrC 3994733 pyrC Escherichia coli UTI89 dihydroorotase YP_540200.1 1166529 R 364106 CDS YP_540201.1 91210215 3994734 complement(1167681..1168298) 1 NC_007946.1 hypothetical protein 1168298 yceB 3994734 yceB Escherichia coli UTI89 hypothetical protein YP_540201.1 1167681 R 364106 CDS YP_540202.1 91210216 3994735 complement(1168375..1169022) 1 NC_007946.1 cofactor involved in the reduction of disulfides; glutaredoxin 2 1169022 grxB 3994735 grxB Escherichia coli UTI89 glutaredoxin 2 YP_540202.1 1168375 R 364106 CDS YP_540203.2 162138452 3994736 complement(1169086..1170294) 1 NC_007946.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1170294 yceL 3994736 yceL Escherichia coli UTI89 multidrug resistance protein MdtH YP_540203.2 1169086 R 364106 CDS YP_540204.1 91210218 3994737 1170530..1171114 1 NC_007946.1 ribosomal-protein-S5-alanine N-acetyltransferase 1171114 rimJ 3994737 rimJ Escherichia coli UTI89 ribosomal-protein-S5-alanine N-acetyltransferase YP_540204.1 1170530 D 364106 CDS YP_540205.1 91210219 3994738 1171125..1171772 1 NC_007946.1 hypothetical protein 1171772 yceH 3994738 yceH Escherichia coli UTI89 hypothetical protein YP_540205.1 1171125 D 364106 CDS YP_540206.1 91210220 3994739 1171774..1172697 1 NC_007946.1 virulence factor 1172697 mviM 3994739 mviM Escherichia coli UTI89 virulence factor YP_540206.1 1171774 D 364106 CDS YP_540207.1 91210221 3994740 1172807..1174342 1 NC_007946.1 virulence factor 1174342 mviN 3994740 mviN Escherichia coli UTI89 virulence factor YP_540207.1 1172807 D 364106 CDS YP_540208.1 91210222 3994741 complement(1174382..1174798) 1 NC_007946.1 flagellar synthesis protein FlgN 1174798 flgN 3994741 flgN Escherichia coli UTI89 flagellar synthesis protein FlgN YP_540208.1 1174382 R 364106 CDS YP_540209.1 91210223 3994742 complement(1174803..1175096) 1 NC_007946.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM 1175096 flgM 3994742 flgM Escherichia coli UTI89 anti-sigma28 factor FlgM YP_540209.1 1174803 R 364106 CDS YP_540210.1 91210224 3994743 complement(1175172..1175831) 1 NC_007946.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1175831 flgA 3994743 flgA Escherichia coli UTI89 flagellar basal body P-ring biosynthesis protein FlgA YP_540210.1 1175172 R 364106 CDS YP_540211.1 91210225 3994744 1175986..1176402 1 NC_007946.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1176402 flgB 3994744 flgB Escherichia coli UTI89 flagellar basal-body rod protein FlgB YP_540211.1 1175986 D 364106 CDS YP_540212.1 91210226 3994422 1176406..1176810 1 NC_007946.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1176810 flgC 3994422 flgC Escherichia coli UTI89 flagellar basal body rod protein FlgC YP_540212.1 1176406 D 364106 CDS YP_540213.1 91210227 3994423 1176822..1177517 1 NC_007946.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1177517 flgD 3994423 flgD Escherichia coli UTI89 flagellar basal body rod modification protein YP_540213.1 1176822 D 364106 CDS YP_540214.1 91210228 3994424 1177542..1178747 1 NC_007946.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1178747 flgE 3994424 flgE Escherichia coli UTI89 flagellar hook protein FlgE YP_540214.1 1177542 D 364106 CDS YP_540215.1 91210229 3994425 1178767..1179522 1 NC_007946.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1179522 flgF 3994425 flgF Escherichia coli UTI89 flagellar basal body rod protein FlgF YP_540215.1 1178767 D 364106 CDS YP_540216.1 91210230 3994426 1179694..1180476 1 NC_007946.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1180476 flgG 3994426 flgG Escherichia coli UTI89 flagellar basal body rod protein FlgG YP_540216.1 1179694 D 364106 CDS YP_540217.1 91210231 3994427 1180514..1181227 1 NC_007946.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1181227 flgH 3994427 flgH Escherichia coli UTI89 flagellar basal body L-ring protein YP_540217.1 1180514 D 364106 CDS YP_540218.1 91210232 3994428 1181236..1182336 1 NC_007946.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1182336 flgI 3994428 flgI Escherichia coli UTI89 flagellar basal body P-ring biosynthesis protein FlgA YP_540218.1 1181236 D 364106 CDS YP_540219.2 162138451 3994429 1182336..1183277 1 NC_007946.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1183277 flgJ 3994429 flgJ Escherichia coli UTI89 flagellar rod assembly protein/muramidase FlgJ YP_540219.2 1182336 D 364106 CDS YP_540220.1 91210234 3994430 1183343..1184986 1 NC_007946.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1184986 flgK 3994430 flgK Escherichia coli UTI89 flagellar hook-associated protein FlgK YP_540220.1 1183343 D 364106 CDS YP_540221.1 91210235 3994431 1184998..1185951 1 NC_007946.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1185951 flgL 3994431 flgL Escherichia coli UTI89 flagellar hook-associated protein FlgL YP_540221.1 1184998 D 364106 CDS YP_540222.1 91210236 3994432 complement(1186146..1189331) 1 NC_007946.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1189331 rne 3994432 rne Escherichia coli UTI89 ribonuclease E YP_540222.1 1186146 R 364106 CDS YP_540223.1 91210237 3994433 1189412..1189786 1 NC_007946.1 hypothetical protein 1189786 3994433 UTI89_C1210 Escherichia coli UTI89 hypothetical protein YP_540223.1 1189412 D 364106 CDS YP_540224.1 91210238 3994434 1189904..1190863 1 NC_007946.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1190863 yceC 3994434 yceC Escherichia coli UTI89 23S rRNA pseudouridylate synthase C YP_540224.1 1189904 D 364106 CDS YP_540225.1 91210239 3994435 complement(1190975..1191598) 1 NC_007946.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1191598 yceF 3994435 yceF Escherichia coli UTI89 Maf-like protein YP_540225.1 1190975 R 364106 CDS YP_540226.1 91210240 3994436 1191758..1192279 1 NC_007946.1 hypothetical protein 1192279 yceD 3994436 yceD Escherichia coli UTI89 hypothetical protein YP_540226.1 1191758 D 364106 CDS YP_540227.1 91210241 3994437 1192331..1192504 1 NC_007946.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1192504 rpmF 3994437 rpmF Escherichia coli UTI89 50S ribosomal protein L32 YP_540227.1 1192331 D 364106 CDS YP_540228.1 91210242 3994438 1192585..1193655 1 NC_007946.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1193655 plsX 3994438 plsX Escherichia coli UTI89 glycerol-3-phosphate acyltransferase PlsX YP_540228.1 1192585 D 364106 CDS YP_540229.1 91210243 3994439 1193723..1194676 1 NC_007946.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1194676 fabH 3994439 fabH Escherichia coli UTI89 3-oxoacyl-ACP synthase YP_540229.1 1193723 D 364106 CDS YP_540230.1 91210244 3994440 1194692..1195621 1 NC_007946.1 malonyl CoA-ACP transacylase 1195621 fabD 3994440 fabD Escherichia coli UTI89 malonyl CoA-ACP transacylase YP_540230.1 1194692 D 364106 CDS YP_540231.1 91210245 3994441 1195634..1196368 1 NC_007946.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1196368 fabG 3994441 fabG Escherichia coli UTI89 3-ketoacyl-ACP reductase YP_540231.1 1195634 D 364106 CDS YP_540232.1 91210246 3993482 complement(1196525..1196899) 1 NC_007946.1 hypothetical protein 1196899 3993482 UTI89_C1219 Escherichia coli UTI89 hypothetical protein YP_540232.1 1196525 R 364106 CDS YP_540233.1 91210247 3993483 1196579..1196815 1 NC_007946.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1196815 acpP 3993483 acpP Escherichia coli UTI89 acyl carrier protein YP_540233.1 1196579 D 364106 CDS YP_540234.1 91210248 3993484 1196902..1198143 1 NC_007946.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1198143 fabF 3993484 fabF Escherichia coli UTI89 3-oxoacyl-ACP synthase YP_540234.1 1196902 D 364106 CDS YP_540235.1 91210249 3993485 1198263..1199072 1 NC_007946.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1199072 pabC 3993485 pabC Escherichia coli UTI89 4-amino-4-deoxychorismate lyase YP_540235.1 1198263 D 364106 CDS YP_540237.1 91210251 3993487 1199075..1200097 1 NC_007946.1 hypothetical protein 1200097 yceG 3993487 yceG Escherichia coli UTI89 hypothetical protein YP_540237.1 1199075 D 364106 CDS YP_540238.1 91210252 3993488 1200087..1200728 1 NC_007946.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1200728 tmk 3993488 tmk Escherichia coli UTI89 thymidylate kinase YP_540238.1 1200087 D 364106 CDS YP_540239.1 91210253 3993489 1200725..1201729 1 NC_007946.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1201729 holB 3993489 holB Escherichia coli UTI89 DNA polymerase III subunit delta' YP_540239.1 1200725 D 364106 CDS YP_540240.1 91210254 3993490 1201680..1202537 1 NC_007946.1 metallodependent hydrolase 1202537 ycfH 3993490 ycfH Escherichia coli UTI89 metallodependent hydrolase YP_540240.1 1201680 D 364106 CDS YP_540241.1 91210255 3993491 1202832..1204265 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1204265 3993491 UTI89_C1228 Escherichia coli UTI89 PTS system glucose-specific transporter subunits IIBC YP_540241.1 1202832 D 364106 CDS YP_540242.1 91210256 3993492 complement(1204325..1206514) 1 NC_007946.1 ferric-rhodotorulic acid outer membrane transporter 1206514 fhuE 3993492 fhuE Escherichia coli UTI89 ferric-rhodotorulic acid outer membrane transporter YP_540242.1 1204325 R 364106 CDS YP_540243.1 91210257 3993493 complement(1206547..1206717) 1 NC_007946.1 hypothetical protein 1206717 3993493 UTI89_C1230 Escherichia coli UTI89 hypothetical protein YP_540243.1 1206547 R 364106 CDS YP_540244.1 91210258 3993494 1206848..1207207 1 NC_007946.1 purine nucleoside phosphoramidase 1207207 ycfF 3993494 ycfF Escherichia coli UTI89 purine nucleoside phosphoramidase YP_540244.1 1206848 D 364106 CDS YP_540245.1 91210259 3993495 1207210..1207587 1 NC_007946.1 hypothetical protein 1207587 ycfL 3993495 ycfL Escherichia coli UTI89 hypothetical protein YP_540245.1 1207210 D 364106 CDS YP_540246.1 91210260 3993496 1207598..1208242 1 NC_007946.1 fibronectin-binding protein B 1208242 3993496 UTI89_C1233 Escherichia coli UTI89 fibronectin-binding protein B YP_540246.1 1207598 D 364106 CDS YP_540247.1 91210261 3993497 1208223..1209047 1 NC_007946.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1209047 thiK 3993497 thiK Escherichia coli UTI89 thiamine kinase YP_540247.1 1208223 D 364106 CDS YP_540248.1 91210262 3993498 1209058..1210083 1 NC_007946.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1210083 ycfO 3993498 ycfO Escherichia coli UTI89 beta-hexosaminidase YP_540248.1 1209058 D 364106 CDS YP_540249.1 91210263 3993499 1210049..1210648 1 NC_007946.1 hypothetical protein 1210648 ycfP 3993499 ycfP Escherichia coli UTI89 hypothetical protein YP_540249.1 1210049 D 364106 CDS YP_540250.1 91210264 3993500 1211020..1212351 1 NC_007946.1 NADH dehydrogenase 1212351 ndh 3993500 ndh Escherichia coli UTI89 NADH dehydrogenase YP_540250.1 1211020 D 364106 CDS YP_540251.1 91210265 3992696 1212539..1213117 1 NC_007946.1 hypothetical protein 1213117 ycfJ 3992696 ycfJ Escherichia coli UTI89 hypothetical protein YP_540251.1 1212539 D 364106 CDS YP_540252.1 91210266 3992697 complement(1213179..1213889) 1 NC_007946.1 hypothetical protein 1213889 ycfQ 3992697 ycfQ Escherichia coli UTI89 hypothetical protein YP_540252.1 1213179 R 364106 CDS YP_540253.1 91210267 3992698 1214052..1214309 1 NC_007946.1 hypothetical protein 1214309 ycfR 3992698 ycfR Escherichia coli UTI89 hypothetical protein YP_540253.1 1214052 D 364106 CDS YP_540254.1 91210268 3992699 complement(1214391..1215353) 1 NC_007946.1 hypothetical protein 1215353 ycfS 3992699 ycfS Escherichia coli UTI89 hypothetical protein YP_540254.1 1214391 R 364106 CDS YP_540255.1 91210269 3992700 complement(1215498..1219007) 1 NC_007946.1 transcription-repair coupling factor 1219007 mfd 3992700 mfd Escherichia coli UTI89 transcription-repair coupling factor YP_540255.1 1215498 R 364106 CDS YP_540256.1 91210270 3992701 complement(1219072..1220145) 1 NC_007946.1 hypothetical protein 1220145 ycfT 3992701 ycfT Escherichia coli UTI89 hypothetical protein YP_540256.1 1219072 R 364106 CDS YP_540257.1 91210271 3992702 1220407..1221606 1 NC_007946.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1221606 ycfU 3992702 ycfU Escherichia coli UTI89 outer membrane-specific lipoprotein transporter subunit LolC YP_540257.1 1220407 D 364106 CDS YP_540258.1 91210272 3992703 1221599..1222300 1 NC_007946.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1222300 lolD 3992703 lolD Escherichia coli UTI89 lipoprotein transporter ATP-binding subunit YP_540258.1 1221599 D 364106 CDS YP_540259.1 91210273 3992704 1222300..1223544 1 NC_007946.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1223544 lolE 3992704 lolE Escherichia coli UTI89 outer membrane-specific lipoprotein transporter subunit LolE YP_540259.1 1222300 D 364106 CDS YP_540260.1 91210274 3992705 1223573..1224484 1 NC_007946.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1224484 ycfX 3992705 ycfX Escherichia coli UTI89 N-acetyl-D-glucosamine kinase YP_540260.1 1223573 D 364106 CDS YP_540261.1 91210275 3992706 1224500..1225321 1 NC_007946.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1225321 cobB 3992706 cobB Escherichia coli UTI89 NAD-dependent deacetylase YP_540261.1 1224500 D 364106 CDS YP_540262.1 91210276 3992707 complement(1225459..1226247) 1 NC_007946.1 hypothetical protein 1226247 ycfZ 3992707 ycfZ Escherichia coli UTI89 hypothetical protein YP_540262.1 1225459 R 364106 CDS YP_540263.1 91210277 3992708 complement(1226244..1226747) 1 NC_007946.1 hypothetical protein 1226747 ymfA 3992708 ymfA Escherichia coli UTI89 hypothetical protein YP_540263.1 1226244 R 364106 CDS YP_540264.1 91210278 3992709 complement(1226763..1227809) 1 NC_007946.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein 1227809 potD 3992709 potD Escherichia coli UTI89 spermidine/putrescine ABC transporter periplasmic substrate-binding protein YP_540264.1 1226763 R 364106 CDS YP_540265.1 91210279 3992710 complement(1227806..1228600) 1 NC_007946.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1228600 potC 3992710 potC Escherichia coli UTI89 spermidine/putrescine ABC transporter membrane protein YP_540265.1 1227806 R 364106 CDS YP_540266.1 91210280 3992711 complement(1228597..1229454) 1 NC_007946.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1229454 potB 3992711 potB Escherichia coli UTI89 spermidine/putrescine ABC transporter membrane protein YP_540266.1 1228597 R 364106 CDS YP_540267.1 91210281 3992712 complement(1229438..1230574) 1 NC_007946.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1230574 potA 3992712 potA Escherichia coli UTI89 putrescine/spermidine ABC transporter ATPase YP_540267.1 1229438 R 364106 CDS YP_540268.1 91210282 3992713 complement(1230553..1230804) 1 NC_007946.1 hypothetical protein 1230804 3992713 UTI89_C1255 Escherichia coli UTI89 hypothetical protein YP_540268.1 1230553 R 364106 CDS YP_540269.1 91210283 3992714 1230824..1232050 1 NC_007946.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1232050 pepT 3992714 pepT Escherichia coli UTI89 peptidase T YP_540269.1 1230824 D 364106 CDS YP_540270.1 91210284 3992715 complement(1232099..1233229) 1 NC_007946.1 hypothetical protein 1233229 3992715 UTI89_C1257 Escherichia coli UTI89 hypothetical protein YP_540270.1 1232099 R 364106 CDS YP_540271.1 91210285 3993600 complement(1233296..1234756) 1 NC_007946.1 sensor protein PhoQ 1234756 phoQ 3993600 phoQ Escherichia coli UTI89 sensor protein PhoQ YP_540271.1 1233296 R 364106 CDS YP_540272.1 91210286 3993601 complement(1234756..1235427) 1 NC_007946.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1235427 phoP 3993601 phoP Escherichia coli UTI89 DNA-binding transcriptional regulator PhoP YP_540272.1 1234756 R 364106 CDS YP_540273.1 91210287 3993602 complement(1235596..1236966) 1 NC_007946.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1236966 purB 3993602 purB Escherichia coli UTI89 adenylosuccinate lyase YP_540273.1 1235596 R 364106 CDS YP_540274.1 91210288 3993603 complement(1236970..1237617) 1 NC_007946.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1237617 ycfC 3993603 ycfC Escherichia coli UTI89 hypothetical protein YP_540274.1 1236970 R 364106 CDS YP_540275.1 91210289 3993604 complement(1237647..1238798) 1 NC_007946.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1238798 mnmA 3993604 mnmA Escherichia coli UTI89 tRNA-specific 2-thiouridylase MnmA YP_540275.1 1237647 R 364106 CDS YP_540276.1 91210290 3993605 complement(1238807..1239268) 1 NC_007946.1 NUDIX family hydrolase 1239268 ymfB 3993605 ymfB Escherichia coli UTI89 NUDIX family hydrolase YP_540276.1 1238807 R 364106 CDS YP_540277.2 162138450 3993606 complement(1239278..1239901) 1 NC_007946.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1239901 rluE 3993606 rluE Escherichia coli UTI89 23S rRNA pseudouridine synthase E YP_540277.2 1239278 R 364106 CDS YP_540278.1 91210292 3993607 complement(1240019..1241200) 1 NC_007946.1 hypothetical protein 1241200 3993607 UTI89_C1265 Escherichia coli UTI89 hypothetical protein YP_540278.1 1240019 R 364106 CDS YP_540279.1 91210293 3993608 1240103..1241353 1 NC_007946.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1241353 icdA 3993608 icdA Escherichia coli UTI89 isocitrate dehydrogenase YP_540279.1 1240103 D 364106 CDS YP_540280.1 91210294 3993609 complement(1241467..1242609) 1 NC_007946.1 prophage lambda integrase 1242609 3993609 UTI89_C1267 Escherichia coli UTI89 prophage lambda integrase YP_540280.1 1241467 R 364106 CDS YP_540281.1 91210295 3993610 complement(1242599..1242835) 1 NC_007946.1 excisionase 1242835 3993610 UTI89_C1268 Escherichia coli UTI89 excisionase YP_540281.1 1242599 R 364106 CDS YP_540282.1 91210296 3993611 complement(1242975..1243214) 1 NC_007946.1 hypothetical protein 1243214 3993611 UTI89_C1269 Escherichia coli UTI89 hypothetical protein YP_540282.1 1242975 R 364106 CDS YP_540283.1 91210297 3993612 1243132..1243596 1 NC_007946.1 hypothetical protein 1243596 3993612 UTI89_C1270 Escherichia coli UTI89 hypothetical protein YP_540283.1 1243132 D 364106 CDS YP_540284.1 91210298 3993613 complement(1243198..1243527) 1 NC_007946.1 hypothetical protein 1243527 3993613 UTI89_C1271 Escherichia coli UTI89 hypothetical protein YP_540284.1 1243198 R 364106 CDS YP_540285.1 91210299 3993614 complement(1243524..1243745) 1 NC_007946.1 C4-type zinc finger protein 1243745 3993614 UTI89_C1272 Escherichia coli UTI89 C4-type zinc finger protein YP_540285.1 1243524 R 364106 CDS YP_540286.1 91210300 3993615 complement(1244132..1244323) 1 NC_007946.1 hypothetical protein 1244323 3993615 UTI89_C1273 Escherichia coli UTI89 hypothetical protein YP_540286.1 1244132 R 364106 CDS YP_540287.1 91210301 3993616 1244275..1244601 1 NC_007946.1 hypothetical protein 1244601 3993616 UTI89_C1274 Escherichia coli UTI89 hypothetical protein YP_540287.1 1244275 D 364106 CDS YP_540288.1 91210302 3993617 complement(1244475..1245155) 1 NC_007946.1 prophage CP-933K exonuclease 1245155 3993617 UTI89_C1275 Escherichia coli UTI89 prophage CP-933K exonuclease YP_540288.1 1244475 R 364106 CDS YP_540289.1 91210303 3993618 complement(1245152..1245937) 1 NC_007946.1 recombination protein Bet of prophage 1245937 bet 3993618 bet Escherichia coli UTI89 recombination protein Bet of prophage YP_540289.1 1245152 R 364106 CDS YP_540290.1 91210304 3991421 complement(1245943..1246239) 1 NC_007946.1 host-nuclease inhibitor protein Gam of bacteriphage 1246239 gamW 3991421 gamW Escherichia coli UTI89 host-nuclease inhibitor protein Gam of bacteriphage YP_540290.1 1245943 R 364106 CDS YP_540291.1 91210305 3991422 complement(1246208..1246360) 1 NC_007946.1 hypothetical protein 1246360 3991422 UTI89_C1278 Escherichia coli UTI89 hypothetical protein YP_540291.1 1246208 R 364106 CDS YP_540292.1 91210306 3991423 complement(1246315..1246584) 1 NC_007946.1 Kil protein 1246584 kil1 3991423 kil1 Escherichia coli UTI89 Kil protein YP_540292.1 1246315 R 364106 CDS YP_540293.1 91210307 3991424 complement(1246427..1246591) 1 NC_007946.1 lambda regulatory protein CIII 1246591 3991424 UTI89_C1280 Escherichia coli UTI89 lambda regulatory protein CIII YP_540293.1 1246427 R 364106 CDS YP_540294.1 91210308 3991425 complement(1246664..1247032) 1 NC_007946.1 bacteriophage lambda single-stranded DNA binding protein 1247032 3991425 UTI89_C1281 Escherichia coli UTI89 bacteriophage lambda single-stranded DNA binding protein YP_540294.1 1246664 R 364106 CDS YP_540295.1 91210309 3991426 complement(1247215..1247415) 1 NC_007946.1 lambda ant-restriction protein 1247415 3991426 UTI89_C1282 Escherichia coli UTI89 lambda ant-restriction protein YP_540295.1 1247215 R 364106 CDS YP_540296.1 91210310 3991427 1247629..1248210 1 NC_007946.1 superinfection exclusion protein B of prophage 1248210 3991427 UTI89_C1283 Escherichia coli UTI89 superinfection exclusion protein B of prophage YP_540296.1 1247629 D 364106 CDS YP_540297.1 91210311 3991428 complement(1248227..1248571) 1 NC_007946.1 N protein 1248571 3991428 UTI89_C1284 Escherichia coli UTI89 N protein YP_540297.1 1248227 R 364106 CDS YP_540298.1 91210312 3991429 complement(1248477..1248659) 1 NC_007946.1 hypothetical protein 1248659 3991429 UTI89_C1285 Escherichia coli UTI89 hypothetical protein YP_540298.1 1248477 R 364106 CDS YP_540299.1 91210313 3991430 complement(1248936..1249688) 1 NC_007946.1 hypothetical protein 1249688 3991430 UTI89_C1286 Escherichia coli UTI89 hypothetical protein YP_540299.1 1248936 R 364106 CDS YP_540300.1 91210314 3991431 complement(1249685..1250242) 1 NC_007946.1 hypothetical protein 1250242 3991431 UTI89_C1287 Escherichia coli UTI89 hypothetical protein YP_540300.1 1249685 R 364106 CDS YP_540301.1 91210315 3991432 complement(1250282..1250935) 1 NC_007946.1 CI repressor of bacteriophage 1250935 3991432 UTI89_C1288 Escherichia coli UTI89 CI repressor of bacteriophage YP_540301.1 1250282 R 364106 CDS YP_540302.1 91210316 3991433 1251410..1251706 1 NC_007946.1 bacteriophage regulatory protein CII 1251706 3991433 UTI89_C1289 Escherichia coli UTI89 bacteriophage regulatory protein CII YP_540302.1 1251410 D 364106 CDS YP_540303.1 91210317 3991434 1251739..1252638 1 NC_007946.1 bacteriophage replication protein O 1252638 3991434 UTI89_C1290 Escherichia coli UTI89 bacteriophage replication protein O YP_540303.1 1251739 D 364106 CDS YP_540304.1 91210318 3991435 1252635..1253336 1 NC_007946.1 bacteriophage replication protein P 1253336 3991435 UTI89_C1291 Escherichia coli UTI89 bacteriophage replication protein P YP_540304.1 1252635 D 364106 CDS YP_540305.1 91210319 3991436 1253333..1253623 1 NC_007946.1 prophage exclusion protein Ren 1253623 3991436 UTI89_C1292 Escherichia coli UTI89 prophage exclusion protein Ren YP_540305.1 1253333 D 364106 CDS YP_540306.1 91210320 3991437 1253697..1254137 1 NC_007946.1 NinB protein encoded within prophage 1254137 ninB1 3991437 ninB1 Escherichia coli UTI89 NinB protein encoded within prophage YP_540306.1 1253697 D 364106 CDS YP_540307.1 91210321 3991438 1254104..1254661 1 NC_007946.1 DNA N-6-adenine-methyltransferase of bacteriophage 1254661 3991438 UTI89_C1294 Escherichia coli UTI89 DNA N-6-adenine-methyltransferase of bacteriophage YP_540307.1 1254104 D 364106 CDS YP_540308.1 91210322 3991439 1254658..1254834 1 NC_007946.1 NinE protein (phage 82- and lambda-like) proteins 1254834 ninE1 3991439 ninE1 Escherichia coli UTI89 NinE protein (phage 82- and lambda-like) proteins YP_540308.1 1254658 D 364106 CDS YP_540309.1 91210323 3991440 1254837..1255178 1 NC_007946.1 hypothetical protein 1255178 3991440 UTI89_C1296 Escherichia coli UTI89 hypothetical protein YP_540309.1 1254837 D 364106 CDS YP_540310.1 91210324 3989959 1255171..1255365 1 NC_007946.1 hypothetical protein 1255365 3989959 UTI89_C1297 Escherichia coli UTI89 hypothetical protein YP_540310.1 1255171 D 364106 CDS YP_540311.1 91210325 3989960 1255385..1255747 1 NC_007946.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1255747 rusA 3989960 rusA Escherichia coli UTI89 endodeoxyribonuclease RUS YP_540311.1 1255385 D 364106 CDS YP_540312.1 91210326 3989961 1255744..1255884 1 NC_007946.1 hypothetical protein 1255884 3989961 UTI89_C1299 Escherichia coli UTI89 hypothetical protein YP_540312.1 1255744 D 364106 CDS YP_540313.1 91210327 3989962 1255955..1256353 1 NC_007946.1 lambdoid prophage DLP12 antitermination protein Q-like protein 1256353 ybcQ1 3989962 ybcQ1 Escherichia coli UTI89 lambdoid prophage DLP12 antitermination protein Q-like protein YP_540313.1 1255955 D 364106 CDS YP_540314.1 91210328 3989963 complement(1256542..1257684) 1 NC_007946.1 porin 1257684 nmpC 3989963 nmpC Escherichia coli UTI89 porin YP_540314.1 1256542 R 364106 CDS YP_540315.1 91210329 3989964 1258213..1258428 1 NC_007946.1 hypothetical protein 1258428 ybcR1 3989964 ybcR1 Escherichia coli UTI89 hypothetical protein YP_540315.1 1258213 D 364106 CDS YP_540316.1 91210330 3989965 1258428..1258925 1 NC_007946.1 lysozyme from lambdoid prophage DLP12 1258925 ybcS1 3989965 ybcS1 Escherichia coli UTI89 lysozyme from lambdoid prophage DLP12 YP_540316.1 1258428 D 364106 CDS YP_540317.1 91210331 3989966 1258910..1259383 1 NC_007946.1 Rz endopeptidase from lambdoid prophage DLP12 1259383 3989966 UTI89_C1304 Escherichia coli UTI89 Rz endopeptidase from lambdoid prophage DLP12 YP_540317.1 1258910 D 364106 CDS YP_540318.1 91210332 3989967 complement(1259415..1259756) 1 NC_007946.1 lambdoid prophage DLP12 Bor-like protein 1259756 ybcU 3989967 ybcU Escherichia coli UTI89 lambdoid prophage DLP12 Bor-like protein YP_540318.1 1259415 R 364106 CDS YP_540319.1 91210333 3989968 1260135..1260515 1 NC_007946.1 prophage TonB-like membrane protein 1260515 3989968 UTI89_C1306 Escherichia coli UTI89 prophage TonB-like membrane protein YP_540319.1 1260135 D 364106 CDS YP_540320.1 91210334 3989969 complement(1260163..1260315) 1 NC_007946.1 hypothetical protein 1260315 3989969 UTI89_C1307 Escherichia coli UTI89 hypothetical protein YP_540320.1 1260163 R 364106 CDS YP_540321.1 91210335 3989970 complement(1260638..1260991) 1 NC_007946.1 hypothetical protein 1260991 3989970 UTI89_C1308 Escherichia coli UTI89 hypothetical protein YP_540321.1 1260638 R 364106 CDS YP_540322.1 91210336 3989971 1260722..1260904 1 NC_007946.1 hypothetical protein 1260904 3989971 UTI89_C1309 Escherichia coli UTI89 hypothetical protein YP_540322.1 1260722 D 364106 CDS YP_540323.1 91210337 3989972 1261134..1261478 1 NC_007946.1 hypothetical protein 1261478 3989972 UTI89_C1310 Escherichia coli UTI89 hypothetical protein YP_540323.1 1261134 D 364106 CDS YP_540324.1 91210338 3989973 1261468..1262016 1 NC_007946.1 Qin prophage packaging protein NU1-like protein 1262016 nohA1 3989973 nohA1 Escherichia coli UTI89 Qin prophage packaging protein NU1-like protein YP_540324.1 1261468 D 364106 CDS YP_540325.1 91210339 3989974 1261964..1263916 1 NC_007946.1 prophage DNA packaging protein terminase large subunit 1263916 3989974 UTI89_C1312 Escherichia coli UTI89 prophage DNA packaging protein terminase large subunit YP_540325.1 1261964 D 364106 CDS YP_540326.1 91210340 3989975 1263900..1264106 1 NC_007946.1 prophage DNA packaging protein 1264106 3989975 UTI89_C1313 Escherichia coli UTI89 prophage DNA packaging protein YP_540326.1 1263900 D 364106 CDS YP_540327.1 91210341 3989976 1264103..1265695 1 NC_007946.1 prophage capsid protein 1265695 3989976 UTI89_C1314 Escherichia coli UTI89 prophage capsid protein YP_540327.1 1264103 D 364106 CDS YP_540328.1 91210342 3989977 1265685..1267190 1 NC_007946.1 bacteriophage head-tail preconnector protein gp5 1267190 3989977 UTI89_C1315 Escherichia coli UTI89 bacteriophage head-tail preconnector protein gp5 YP_540328.1 1265685 D 364106 CDS YP_540329.1 91210343 3992450 1267227..1267574 1 NC_007946.1 bacteriophage capsid protein small subunit 1267574 3992450 UTI89_C1316 Escherichia coli UTI89 bacteriophage capsid protein small subunit YP_540329.1 1267227 D 364106 CDS YP_540330.1 91210344 3992451 1267632..1268660 1 NC_007946.1 prophage capsid protein gp7 1268660 3992451 UTI89_C1317 Escherichia coli UTI89 prophage capsid protein gp7 YP_540330.1 1267632 D 364106 CDS YP_540331.1 91210345 3992452 1268664..1269086 1 NC_007946.1 hypothetical protein 1269086 3992452 UTI89_C1318 Escherichia coli UTI89 hypothetical protein YP_540331.1 1268664 D 364106 CDS YP_540332.1 91210346 3992453 1269058..1269432 1 NC_007946.1 prophage head-tail joining protein 1269432 3992453 UTI89_C1319 Escherichia coli UTI89 prophage head-tail joining protein YP_540332.1 1269058 D 364106 CDS YP_540333.1 91210347 3992454 1269444..1270022 1 NC_007946.1 prophage tail fiber component Z 1270022 3992454 UTI89_C1320 Escherichia coli UTI89 prophage tail fiber component Z YP_540333.1 1269444 D 364106 CDS YP_540334.1 91210348 3992455 1270019..1270414 1 NC_007946.1 prophage tail component 1270414 3992455 UTI89_C1321 Escherichia coli UTI89 prophage tail component YP_540334.1 1270019 D 364106 CDS YP_540335.1 91210349 3992456 1270392..1271162 1 NC_007946.1 tail component of prophage CP-933X 1271162 3992456 UTI89_C1322 Escherichia coli UTI89 tail component of prophage CP-933X YP_540335.1 1270392 D 364106 CDS YP_540336.1 91210350 3992457 1271178..1271600 1 NC_007946.1 prophage tail component 1271600 3992457 UTI89_C1323 Escherichia coli UTI89 prophage tail component YP_540336.1 1271178 D 364106 CDS YP_540337.1 91210351 3992458 1271582..1272016 1 NC_007946.1 prophage tail component 1272016 3992458 UTI89_C1324 Escherichia coli UTI89 prophage tail component YP_540337.1 1271582 D 364106 CDS YP_540338.1 91210352 3992459 1272009..1274570 1 NC_007946.1 prophage tail component 1274570 3992459 UTI89_C1325 Escherichia coli UTI89 prophage tail component YP_540338.1 1272009 D 364106 CDS YP_540339.1 91210353 3992460 1274567..1274896 1 NC_007946.1 minor tail protein 1274896 3992460 UTI89_C1326 Escherichia coli UTI89 minor tail protein YP_540339.1 1274567 D 364106 CDS YP_540340.1 91210354 3992461 complement(1274800..1275450) 1 NC_007946.1 hypothetical protein 1275450 3992461 UTI89_C1327 Escherichia coli UTI89 hypothetical protein YP_540340.1 1274800 R 364106 CDS YP_540341.1 91210355 3992462 1274896..1275594 1 NC_007946.1 prophage tail component 1275594 3992462 UTI89_C1328 Escherichia coli UTI89 prophage tail component YP_540341.1 1274896 D 364106 CDS YP_540342.1 91210356 3992463 1275600..1276343 1 NC_007946.1 prophage tail component 1276343 3992463 UTI89_C1329 Escherichia coli UTI89 prophage tail component YP_540342.1 1275600 D 364106 CDS YP_540343.1 91210357 3992464 1276280..1276912 1 NC_007946.1 prophage tail component 1276912 3992464 UTI89_C1330 Escherichia coli UTI89 prophage tail component YP_540343.1 1276280 D 364106 CDS YP_540344.1 91210358 3992465 1276973..1280455 1 NC_007946.1 prophage tail component 1280455 3992465 UTI89_C1331 Escherichia coli UTI89 prophage tail component YP_540344.1 1276973 D 364106 CDS YP_540345.1 91210359 3992466 1280508..1282574 1 NC_007946.1 hypothetical protein 1282574 3992466 UTI89_C1332 Escherichia coli UTI89 hypothetical protein YP_540345.1 1280508 D 364106 CDS YP_540346.1 91210360 3992467 1282571..1282849 1 NC_007946.1 hypothetical protein 1282849 3992467 UTI89_C1333 Escherichia coli UTI89 hypothetical protein YP_540346.1 1282571 D 364106 CDS YP_540347.1 91210361 3992468 1282862..1283155 1 NC_007946.1 hypothetical protein 1283155 3992468 UTI89_C1334 Escherichia coli UTI89 hypothetical protein YP_540347.1 1282862 D 364106 CDS YP_540348.1 91210362 3992469 complement(1282877..1283317) 1 NC_007946.1 hypothetical protein 1283317 3992469 UTI89_C1335 Escherichia coli UTI89 hypothetical protein YP_540348.1 1282877 R 364106 CDS YP_540349.1 91210363 3990423 complement(1283247..1284104) 1 NC_007946.1 SitD protein 1284104 sitD 3990423 sitD Escherichia coli UTI89 SitD protein YP_540349.1 1283247 R 364106 CDS YP_540350.1 91210364 3990424 complement(1284101..1284958) 1 NC_007946.1 SitC protein 1284958 sitC 3990424 sitC Escherichia coli UTI89 SitC protein YP_540350.1 1284101 R 364106 CDS YP_540351.1 91210365 3990425 complement(1284955..1285782) 1 NC_007946.1 SitB protein 1285782 sitB 3990425 sitB Escherichia coli UTI89 SitB protein YP_540351.1 1284955 R 364106 CDS YP_540352.1 91210366 3990426 complement(1285782..1286696) 1 NC_007946.1 iron transport protein, periplasmic-binding protein SitA 1286696 sitA 3990426 sitA Escherichia coli UTI89 iron transport protein, periplasmic-binding protein SitA YP_540352.1 1285782 R 364106 CDS YP_540353.1 91210367 3990427 1286975..1287259 1 NC_007946.1 hypothetical protein 1287259 3990427 UTI89_C1340 Escherichia coli UTI89 hypothetical protein YP_540353.1 1286975 D 364106 CDS YP_540354.1 91210368 3990428 1287383..1288153 1 NC_007946.1 hypothetical protein 1288153 3990428 UTI89_C1341 Escherichia coli UTI89 hypothetical protein YP_540354.1 1287383 D 364106 CDS YP_540355.1 91210369 3990429 1288625..1288777 1 NC_007946.1 isocitrate dehydrogenase 1288777 3990429 UTI89_C1342 Escherichia coli UTI89 isocitrate dehydrogenase YP_540355.1 1288625 D 364106 CDS YP_540356.1 91210370 3990430 complement(1289039..1289443) 1 NC_007946.1 hypothetical protein 1289443 ycgX 3990430 ycgX Escherichia coli UTI89 hypothetical protein YP_540356.1 1289039 R 364106 CDS YP_540357.1 91210371 3990431 complement(1289664..1290395) 1 NC_007946.1 transcriptional regulator YcgE 1290395 ycgE 3990431 ycgE Escherichia coli UTI89 transcriptional regulator YcgE YP_540357.1 1289664 R 364106 CDS YP_540358.1 91210372 3990432 complement(1290305..1290457) 1 NC_007946.1 hypothetical protein 1290457 3990432 UTI89_C1345 Escherichia coli UTI89 hypothetical protein YP_540358.1 1290305 R 364106 CDS YP_540359.1 91210373 3990433 complement(1290600..1291889) 1 NC_007946.1 hypothetical protein 1291889 ycgF 3990433 ycgF Escherichia coli UTI89 hypothetical protein YP_540359.1 1290600 R 364106 CDS YP_540360.1 91210374 3990434 1292125..1292361 1 NC_007946.1 hypothetical protein 1292361 ycgZ 3990434 ycgZ Escherichia coli UTI89 hypothetical protein YP_540360.1 1292125 D 364106 CDS YP_540361.1 91210375 3990435 complement(1292338..1292511) 1 NC_007946.1 hypothetical protein 1292511 3990435 UTI89_C1348 Escherichia coli UTI89 hypothetical protein YP_540361.1 1292338 R 364106 CDS YP_540362.1 91210376 3990436 1292404..1292676 1 NC_007946.1 hypothetical protein 1292676 ymgA 3990436 ymgA Escherichia coli UTI89 hypothetical protein YP_540362.1 1292404 D 364106 CDS YP_540363.1 91210377 3990437 complement(1292715..1293218) 1 NC_007946.1 hypothetical protein 1293218 3990437 UTI89_C1350 Escherichia coli UTI89 hypothetical protein YP_540363.1 1292715 R 364106 CDS YP_540364.1 91210378 3990438 complement(1293229..1293441) 1 NC_007946.1 hypothetical protein 1293441 3990438 UTI89_C1351 Escherichia coli UTI89 hypothetical protein YP_540364.1 1293229 R 364106 CDS YP_540365.1 91210379 3990439 1293507..1293761 1 NC_007946.1 hypothetical protein 1293761 3990439 UTI89_C1352 Escherichia coli UTI89 hypothetical protein YP_540365.1 1293507 D 364106 CDS YP_540366.1 91210380 3990440 1295151..1295678 1 NC_007946.1 hypothetical protein 1295678 3990440 UTI89_C1353 Escherichia coli UTI89 hypothetical protein YP_540366.1 1295151 D 364106 CDS YP_540367.1 91210381 3990441 complement(1295736..1296071) 1 NC_007946.1 hypothetical protein 1296071 ymgD 3990441 ymgD Escherichia coli UTI89 hypothetical protein YP_540367.1 1295736 R 364106 CDS YP_540368.1 91210382 3989803 complement(1296075..1296419) 1 NC_007946.1 hypothetical protein 1296419 3989803 UTI89_C1355 Escherichia coli UTI89 hypothetical protein YP_540368.1 1296075 R 364106 CDS YP_540369.1 91210383 3989804 complement(1296421..1296594) 1 NC_007946.1 hypothetical protein 1296594 3989804 UTI89_C1356 Escherichia coli UTI89 hypothetical protein YP_540369.1 1296421 R 364106 CDS YP_540370.1 91210384 3989805 1297012..1297338 1 NC_007946.1 hypothetical protein 1297338 3989805 UTI89_C1357 Escherichia coli UTI89 hypothetical protein YP_540370.1 1297012 D 364106 CDS YP_540371.1 91210385 3989806 1297384..1297569 1 NC_007946.1 hypothetical protein 1297569 3989806 UTI89_C1358 Escherichia coli UTI89 hypothetical protein YP_540371.1 1297384 D 364106 CDS YP_540372.1 91210386 3989807 complement(1297711..1297977) 1 NC_007946.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1297977 minE 3989807 minE Escherichia coli UTI89 cell division topological specificity factor MinE YP_540372.1 1297711 R 364106 CDS YP_540373.1 91210387 3989808 complement(1297981..1298793) 1 NC_007946.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1298793 minD 3989808 minD Escherichia coli UTI89 cell division inhibitor MinD YP_540373.1 1297981 R 364106 CDS YP_540374.2 162138449 3989809 complement(1298817..1299512) 1 NC_007946.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1299512 minC 3989809 minC Escherichia coli UTI89 septum formation inhibitor YP_540374.2 1298817 R 364106 CDS YP_540375.1 91210389 3989810 1299652..1299879 1 NC_007946.1 hypothetical protein 1299879 3989810 UTI89_C1362 Escherichia coli UTI89 hypothetical protein YP_540375.1 1299652 D 364106 CDS YP_540376.1 91210390 3989811 1300032..1300400 1 NC_007946.1 hypothetical protein 1300400 ycgJ 3989811 ycgJ Escherichia coli UTI89 hypothetical protein YP_540376.1 1300032 D 364106 CDS YP_540377.1 91210391 3989812 complement(1300520..1300921) 1 NC_007946.1 protein YcgK 1300921 ycgK 3989812 ycgK Escherichia coli UTI89 protein YcgK YP_540377.1 1300520 R 364106 CDS YP_540378.1 91210392 3989813 1301130..1301456 1 NC_007946.1 hypothetical protein 1301456 ycgL 3989813 ycgL Escherichia coli UTI89 hypothetical protein YP_540378.1 1301130 D 364106 CDS YP_540379.1 91210393 3989814 1301528..1302187 1 NC_007946.1 hypothetical protein 1302187 ycgM 3989814 ycgM Escherichia coli UTI89 hypothetical protein YP_540379.1 1301528 D 364106 CDS YP_540380.2 162138448 3989815 1302279..1302725 1 NC_007946.1 hypothetical protein 1302725 ycgN 3989815 ycgN Escherichia coli UTI89 hypothetical protein YP_540380.2 1302279 D 364106 CDS YP_540381.1 91210395 3989816 complement(1302996..1303214) 1 NC_007946.1 hypothetical protein 1303214 3989816 UTI89_C1368 Escherichia coli UTI89 hypothetical protein YP_540381.1 1302996 R 364106 CDS YP_540382.1 91210396 3989817 1303519..1303938 1 NC_007946.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1303938 umuD 3989817 umuD Escherichia coli UTI89 DNA polymerase V subunit UmuD YP_540382.1 1303519 D 364106 CDS YP_540383.1 91210397 3989818 1303938..1305206 1 NC_007946.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1305206 umuC 3989818 umuC Escherichia coli UTI89 DNA polymerase V subunit UmuC YP_540383.1 1303938 D 364106 CDS YP_540384.1 91210398 3989819 complement(1305251..1305787) 1 NC_007946.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1305787 dsbB 3989819 dsbB Escherichia coli UTI89 disulfide bond formation protein B YP_540384.1 1305251 R 364106 CDS YP_540385.1 91210399 3989820 complement(1305927..1307522) 1 NC_007946.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1307522 nhaB 3989820 nhaB Escherichia coli UTI89 sodium/proton antiporter YP_540385.1 1305927 R 364106 CDS YP_540386.1 91210400 3989821 1307690..1308409 1 NC_007946.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1308409 fadR 3989821 fadR Escherichia coli UTI89 fatty acid metabolism regulator YP_540386.1 1307690 D 364106 CDS YP_540387.1 91210401 3989822 complement(1308572..1310104) 1 NC_007946.1 SpoVR family protein 1310104 ycgB 3989822 ycgB Escherichia coli UTI89 SpoVR family protein YP_540387.1 1308572 R 364106 CDS YP_540388.1 91210402 3994253 1310428..1311732 1 NC_007946.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1311732 dadA 3994253 dadA Escherichia coli UTI89 D-amino acid dehydrogenase small subunit YP_540388.1 1310428 D 364106 CDS YP_540389.1 91210403 3994254 1311742..1312812 1 NC_007946.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1312812 dadX 3994254 dadX Escherichia coli UTI89 alanine racemase YP_540389.1 1311742 D 364106 CDS YP_540390.1 91210404 3994255 complement(1312869..1314605) 1 NC_007946.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1314605 ycgO 3994255 ycgO Escherichia coli UTI89 potassium/proton antiporter YP_540390.1 1312869 R 364106 CDS YP_540391.1 91210405 3994256 complement(1314700..1315614) 1 NC_007946.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1315614 ldcA 3994256 ldcA Escherichia coli UTI89 L,D-carboxypeptidase A YP_540391.1 1314700 R 364106 CDS YP_540393.1 91210407 3994258 1315600..1316325 1 NC_007946.1 murein transglycosylase E 1316325 mltE 3994258 mltE Escherichia coli UTI89 murein transglycosylase E YP_540393.1 1315600 D 364106 CDS YP_540394.1 91210408 3994259 complement(1316327..1317061) 1 NC_007946.1 hypothetical protein 1317061 ycgR 3994259 ycgR Escherichia coli UTI89 hypothetical protein YP_540394.1 1316327 R 364106 CDS YP_540395.1 91210409 3994260 1317229..1317516 1 NC_007946.1 transglycosylase associated protein 1317516 ymgE 3994260 ymgE Escherichia coli UTI89 transglycosylase associated protein YP_540395.1 1317229 D 364106 CDS YP_540396.1 91210410 3994261 complement(1317566..1319557) 1 NC_007946.1 TonB dependent outer membrane receptor 1319557 prrA 3994261 prrA Escherichia coli UTI89 TonB dependent outer membrane receptor YP_540396.1 1317566 R 364106 CDS YP_540397.1 91210411 3994262 complement(1319562..1320416) 1 NC_007946.1 involved in molybdenum transport; molybdenum transport protein ModD 1320416 modD 3994262 modD Escherichia coli UTI89 molybdenum transport protein ModD YP_540397.1 1319562 R 364106 CDS YP_540398.1 91210412 3994263 complement(1320413..1321225) 1 NC_007946.1 hypothetical protein 1321225 3994263 UTI89_C1385 Escherichia coli UTI89 hypothetical protein YP_540398.1 1320413 R 364106 CDS YP_540399.1 91210413 3994264 complement(1321235..1321993) 1 NC_007946.1 iron ABC transporter ATP-binding protein 1321993 3994264 UTI89_C1386 Escherichia coli UTI89 iron ABC transporter ATP-binding protein YP_540399.1 1321235 R 364106 CDS YP_540400.1 91210414 3994265 complement(1321990..1322970) 1 NC_007946.1 iron ABC transporter permease 1322970 3994265 UTI89_C1387 Escherichia coli UTI89 iron ABC transporter permease YP_540400.1 1321990 R 364106 CDS YP_540401.1 91210415 3994266 complement(1322970..1323992) 1 NC_007946.1 hypothetical protein 1323992 3994266 UTI89_C1388 Escherichia coli UTI89 hypothetical protein YP_540401.1 1322970 R 364106 CDS YP_540402.1 91210416 3994267 complement(1324329..1326026) 1 NC_007946.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1326026 treA 3994267 treA Escherichia coli UTI89 trehalase YP_540402.1 1324329 R 364106 CDS YP_540403.1 91210417 3994268 1325971..1326186 1 NC_007946.1 hypothetical protein 1326186 3994268 UTI89_C1390 Escherichia coli UTI89 hypothetical protein YP_540403.1 1325971 D 364106 CDS YP_540404.1 91210418 3994269 complement(1326345..1327769) 1 NC_007946.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit M 1327769 ycgC 3994269 ycgC Escherichia coli UTI89 dihydroxyacetone kinase subunit M YP_540404.1 1326345 R 364106 CDS YP_540405.1 91210419 3994270 complement(1327774..1328484) 1 NC_007946.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1328484 ycgS 3994270 ycgS Escherichia coli UTI89 dihydroxyacetone kinase subunit DhaL YP_540405.1 1327774 R 364106 CDS YP_540406.1 91210420 3994271 complement(1328417..1329517) 1 NC_007946.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1329517 ycgT 3994271 ycgT Escherichia coli UTI89 dihydroxyacetone kinase subunit DhaK YP_540406.1 1328417 R 364106 CDS YP_540407.1 91210421 3989861 1329706..1331634 1 NC_007946.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1331634 3989861 UTI89_C1394 Escherichia coli UTI89 DNA-binding transcriptional regulator DhaR YP_540407.1 1329706 D 364106 CDS YP_540408.1 91210422 3989862 1331644..1331829 1 NC_007946.1 hypothetical protein 1331829 3989862 UTI89_C1395 Escherichia coli UTI89 hypothetical protein YP_540408.1 1331644 D 364106 CDS YP_540409.1 91210423 3989863 complement(1331672..1331902) 1 NC_007946.1 hypothetical protein 1331902 3989863 UTI89_C1396 Escherichia coli UTI89 hypothetical protein YP_540409.1 1331672 R 364106 CDS YP_540410.1 91210424 3989864 complement(1332038..1333129) 1 NC_007946.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1333129 ychF 3989864 ychF Escherichia coli UTI89 GTP-dependent nucleic acid-binding protein EngD YP_540410.1 1332038 R 364106 CDS YP_540411.1 91210425 3989865 complement(1333246..1333830) 1 NC_007946.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1333830 pth 3989865 pth Escherichia coli UTI89 peptidyl-tRNA hydrolase YP_540411.1 1333246 R 364106 CDS YP_540412.1 91210426 3989866 1334108..1334386 1 NC_007946.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1334386 ychH 3989866 ychH Escherichia coli UTI89 hypothetical protein YP_540412.1 1334108 D 364106 CDS YP_540413.1 91210427 3989867 complement(1334441..1336120) 1 NC_007946.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1336120 ychM 3989867 ychM Escherichia coli UTI89 sulfate transporter YchM YP_540413.1 1334441 R 364106 CDS YP_540414.1 91210428 3989868 complement(1336245..1337258) 1 NC_007946.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1337258 prsA 3989868 prsA Escherichia coli UTI89 ribose-phosphate pyrophosphokinase YP_540414.1 1336245 R 364106 CDS YP_540415.1 91210429 3989869 complement(1337343..1338194) 1 NC_007946.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1338194 ipk 3989869 ipk Escherichia coli UTI89 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_540415.1 1337343 R 364106 CDS YP_540416.1 91210430 3989870 complement(1338194..1338883) 1 NC_007946.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 1338883 lolB 3989870 lolB Escherichia coli UTI89 molecular chaperone LolB YP_540416.1 1338194 R 364106 CDS YP_540417.1 91210431 3989871 1338833..1340287 1 NC_007946.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1340287 hemA 3989871 hemA Escherichia coli UTI89 glutamyl-tRNA reductase YP_540417.1 1338833 D 364106 CDS YP_540418.1 91210432 3989872 1340329..1341411 1 NC_007946.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1341411 prfA 3989872 prfA Escherichia coli UTI89 peptide chain release factor 1 YP_540418.1 1340329 D 364106 CDS YP_540419.1 91210433 3989873 1341411..1342244 1 NC_007946.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1342244 hemK 3989873 hemK Escherichia coli UTI89 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_540419.1 1341411 D 364106 CDS YP_540420.1 91210434 3989874 1342241..1342633 1 NC_007946.1 transcriptional regulator 1342633 sirB2 3989874 sirB2 Escherichia coli UTI89 transcriptional regulator YP_540420.1 1342241 D 364106 CDS YP_540421.1 91210435 3989875 1342637..1343446 1 NC_007946.1 transcriptional regulator 1343446 ychA 3989875 ychA Escherichia coli UTI89 transcriptional regulator YP_540421.1 1342637 D 364106 CDS YP_540422.1 91210436 3989876 1343482..1344336 1 NC_007946.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1344336 kdsA 3989876 kdsA Escherichia coli UTI89 2-dehydro-3-deoxyphosphooctonate aldolase YP_540422.1 1343482 D 364106 CDS YP_540423.1 91210437 3989877 1344346..1344609 1 NC_007946.1 hypothetical protein 1344609 3989877 UTI89_C1410 Escherichia coli UTI89 hypothetical protein YP_540423.1 1344346 D 364106 CDS YP_540424.1 91210438 3989878 complement(1344997..1346184) 1 NC_007946.1 calcium/sodium:proton antiporter 1346184 chaA 3989878 chaA Escherichia coli UTI89 calcium/sodium:proton antiporter YP_540424.1 1344997 R 364106 CDS YP_540425.1 91210439 3989879 complement(1346361..1346660) 1 NC_007946.1 hypothetical protein 1346660 3989879 UTI89_C1412 Escherichia coli UTI89 hypothetical protein YP_540425.1 1346361 R 364106 CDS YP_540426.1 91210440 3989880 1346367..1346597 1 NC_007946.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1346597 chaB 3989880 chaB Escherichia coli UTI89 cation transport regulator YP_540426.1 1346367 D 364106 CDS YP_540427.1 91210441 3994557 1346719..1347450 1 NC_007946.1 cation transport protein ChaC 1347450 chaC 3994557 chaC Escherichia coli UTI89 cation transport protein ChaC YP_540427.1 1346719 D 364106 CDS YP_540428.1 91210442 3994558 complement(1347494..1347847) 1 NC_007946.1 hypothetical protein 1347847 ychN 3994558 ychN Escherichia coli UTI89 hypothetical protein YP_540428.1 1347494 R 364106 CDS YP_540429.1 91210443 3994559 1348032..1349426 1 NC_007946.1 hypothetical protein 1349426 ychP 3994559 ychP Escherichia coli UTI89 hypothetical protein YP_540429.1 1348032 D 364106 CDS YP_540430.1 91210444 3994560 complement(1349427..1350143) 1 NC_007946.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1350143 narL 3994560 narL Escherichia coli UTI89 transcriptional regulator NarL YP_540430.1 1349427 R 364106 CDS YP_540431.1 91210445 3994561 complement(1350070..1351866) 1 NC_007946.1 nitrate/nitrite sensor protein NarX 1351866 narX 3994561 narX Escherichia coli UTI89 nitrate/nitrite sensor protein NarX YP_540431.1 1350070 R 364106 CDS YP_540432.1 91210446 3994562 1351892..1352110 1 NC_007946.1 hypothetical protein 1352110 3994562 UTI89_C1419 Escherichia coli UTI89 hypothetical protein YP_540432.1 1351892 D 364106 CDS YP_540433.1 91210447 3994563 1352199..1353596 1 NC_007946.1 nitrite extrusion protein 1353596 narK 3994563 narK Escherichia coli UTI89 nitrite extrusion protein YP_540433.1 1352199 D 364106 CDS YP_540434.1 91210448 3994564 1353989..1357732 1 NC_007946.1 respiratory nitrate reductase 1 subunit alpha 1357732 narG 3994564 narG Escherichia coli UTI89 respiratory nitrate reductase 1 subunit alpha YP_540434.1 1353989 D 364106 CDS YP_540435.1 91210449 3994565 1357729..1359267 1 NC_007946.1 respiratory nitrate reductase 1 subunit beta 1359267 narH 3994565 narH Escherichia coli UTI89 respiratory nitrate reductase 1 subunit beta YP_540435.1 1357729 D 364106 CDS YP_540436.1 91210450 3994566 1359264..1359974 1 NC_007946.1 nitrate reductase 1 subunit delta 1359974 narJ 3994566 narJ Escherichia coli UTI89 nitrate reductase 1 subunit delta YP_540436.1 1359264 D 364106 CDS YP_540437.1 91210451 3994567 1359974..1360651 1 NC_007946.1 nitrate reductase 1, cytochrome b(NR) subunit gamma 1360651 narI 3994567 narI Escherichia coli UTI89 nitrate reductase 1, cytochrome b(NR) subunit gamma YP_540437.1 1359974 D 364106 CDS YP_540438.1 91210452 3994568 complement(1360704..1361933) 1 NC_007946.1 Tpn1330-like protein 1361933 3994568 UTI89_C1425 Escherichia coli UTI89 Tpn1330-like protein YP_540438.1 1360704 R 364106 CDS YP_540439.1 91210453 3994571 complement(1362696..1363538) 1 NC_007946.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1363538 purU 3994571 purU Escherichia coli UTI89 formyltetrahydrofolate deformylase YP_540439.1 1362696 R 364106 CDS YP_540440.2 162138447 3994572 complement(1363588..1364046) 1 NC_007946.1 hypothetical protein 1364046 ychJ 3994572 ychJ Escherichia coli UTI89 hypothetical protein YP_540440.2 1363588 R 364106 CDS YP_540441.1 91210455 3994573 1364120..1365064 1 NC_007946.1 hypothetical protein 1365064 ychK 3994573 ychK Escherichia coli UTI89 hypothetical protein YP_540441.1 1364120 D 364106 CDS YP_540442.1 91210456 3993252 1365156..1366169 1 NC_007946.1 response regulator of RpoS 1366169 rssB 3993252 rssB Escherichia coli UTI89 response regulator of RpoS YP_540442.1 1365156 D 364106 CDS YP_540443.1 91210457 3993253 1366371..1367279 1 NC_007946.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1367279 galU 3993253 galU Escherichia coli UTI89 UTP-glucose-1-phosphate uridylyltransferase YP_540443.1 1366371 D 364106 CDS YP_540444.1 91210458 3993254 1367387..1367740 1 NC_007946.1 hypothetical protein 1367740 3993254 UTI89_C1433 Escherichia coli UTI89 hypothetical protein YP_540444.1 1367387 D 364106 CDS YP_540445.1 91210459 3993255 complement(1367423..1367836) 1 NC_007946.1 global DNA-binding transcriptional dual regulator H-NS 1367836 hns 3993255 hns Escherichia coli UTI89 global DNA-binding transcriptional dual regulator H-NS YP_540445.1 1367423 R 364106 CDS YP_540446.1 91210460 3993256 complement(1367928..1368056) 1 NC_007946.1 hypothetical protein 1368056 3993256 UTI89_C1435 Escherichia coli UTI89 hypothetical protein YP_540446.1 1367928 R 364106 CDS YP_540447.1 91210461 3993257 1368440..1369057 1 NC_007946.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1369057 tdk 3993257 tdk Escherichia coli UTI89 thymidine kinase YP_540447.1 1368440 D 364106 CDS YP_540448.1 91210462 3993258 complement(1369184..1370389) 1 NC_007946.1 transposase InsG for insertion sequence element IS4 1370389 3993258 UTI89_C1437 Escherichia coli UTI89 transposase InsG for insertion sequence element IS4 YP_540448.1 1369184 R 364106 CDS YP_540449.1 91210463 3993259 complement(1370515..1373190) 1 NC_007946.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1373190 adhE 3993259 adhE Escherichia coli UTI89 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_540449.1 1370515 R 364106 CDS YP_540450.1 91210464 3993260 1373667..1374314 1 NC_007946.1 hypothetical protein 1374314 ychE 3993260 ychE Escherichia coli UTI89 hypothetical protein YP_540450.1 1373667 D 364106 CDS YP_540451.1 91210465 3993261 complement(1374472..1374786) 1 NC_007946.1 hypothetical protein 1374786 3993261 UTI89_C1440 Escherichia coli UTI89 hypothetical protein YP_540451.1 1374472 R 364106 CDS YP_540452.1 91210466 3993262 1374980..1376683 1 NC_007946.1 periplasmic oligopeptide-binding protein 1376683 oppA 3993262 oppA Escherichia coli UTI89 periplasmic oligopeptide-binding protein YP_540452.1 1374980 D 364106 CDS YP_540453.1 91210467 3993263 1376769..1377689 1 NC_007946.1 oligopeptide transporter permease 1377689 oppB 3993263 oppB Escherichia coli UTI89 oligopeptide transporter permease YP_540453.1 1376769 D 364106 CDS YP_540454.1 91210468 3993264 1377704..1378612 1 NC_007946.1 oligopeptide transport system permease oppC 1378612 oppC 3993264 oppC Escherichia coli UTI89 oligopeptide transport system permease oppC YP_540454.1 1377704 D 364106 CDS YP_540455.1 91210469 3993265 1378624..1379637 1 NC_007946.1 oligopeptide transporter ATP-binding protein 1379637 oppD 3993265 oppD Escherichia coli UTI89 oligopeptide transporter ATP-binding protein YP_540455.1 1378624 D 364106 CDS YP_540456.1 91210470 3993266 1379634..1380638 1 NC_007946.1 oligopeptide transport ATP-binding protein OppF 1380638 oppF 3993266 oppF Escherichia coli UTI89 oligopeptide transport ATP-binding protein OppF YP_540456.1 1379634 D 364106 CDS YP_540457.1 91210471 3993267 complement(1380691..1381098) 1 NC_007946.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1381098 yciU 3993267 yciU Escherichia coli UTI89 dsDNA-mimic protein YP_540457.1 1380691 R 364106 CDS YP_540458.1 91210472 3993268 complement(1381055..1382515) 1 NC_007946.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1382515 cls 3993268 cls Escherichia coli UTI89 cardiolipin synthetase YP_540458.1 1381055 R 364106 CDS YP_540459.1 91210473 3993269 1382547..1382831 1 NC_007946.1 hypothetical protein 1382831 3993269 UTI89_C1448 Escherichia coli UTI89 hypothetical protein YP_540459.1 1382547 D 364106 CDS YP_540460.1 91210474 3993270 complement(1382886..1384157) 1 NC_007946.1 voltage-gated potassium channel 1384157 kch 3993270 kch Escherichia coli UTI89 voltage-gated potassium channel YP_540460.1 1382886 R 364106 CDS YP_540461.2 162138446 3993271 complement(1384439..1384735) 1 NC_007946.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1384735 yciI 3993271 yciI Escherichia coli UTI89 hypothetical protein YP_540461.2 1384439 R 364106 CDS YP_540462.1 91210476 3991369 1384908..1385675 1 NC_007946.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1385675 tonB 3991369 tonB Escherichia coli UTI89 transport protein TonB YP_540462.1 1384908 D 364106 CDS YP_540463.1 91210477 3991370 complement(1385141..1385386) 1 NC_007946.1 hypothetical protein 1385386 3991370 UTI89_C1452 Escherichia coli UTI89 hypothetical protein YP_540463.1 1385141 R 364106 CDS YP_540464.1 91210478 3991371 complement(1385715..1386113) 1 NC_007946.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase 1386113 yciA 3991371 yciA Escherichia coli UTI89 acyl-CoA thioester hydrolase YP_540464.1 1385715 R 364106 CDS YP_540465.1 91210479 3991372 complement(1386219..1386758) 1 NC_007946.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1386758 ispZ 3991372 ispZ Escherichia coli UTI89 intracellular septation protein A YP_540465.1 1386219 R 364106 CDS YP_540466.1 91210480 3991373 complement(1386788..1387531) 1 NC_007946.1 hypothetical protein 1387531 yciC 3991373 yciC Escherichia coli UTI89 hypothetical protein YP_540466.1 1386788 R 364106 CDS YP_540467.1 91210481 3991374 1387809..1388525 1 NC_007946.1 receptor for colicin S4; outer membrane protein W 1388525 ompW 3991374 ompW Escherichia coli UTI89 outer membrane protein W YP_540467.1 1387809 D 364106 CDS YP_540468.1 91210482 3991375 complement(1388571..1389701) 1 NC_007946.1 prophage CP-933O integrase 1389701 intO 3991375 intO Escherichia coli UTI89 prophage CP-933O integrase YP_540468.1 1388571 R 364106 CDS YP_540469.1 91210483 3991376 complement(1389679..1389927) 1 NC_007946.1 excisionase 1389927 3991376 UTI89_C1458 Escherichia coli UTI89 excisionase YP_540469.1 1389679 R 364106 CDS YP_540470.1 91210484 3991377 complement(1389992..1392463) 1 NC_007946.1 prophage CP-933O exonuclease VIII 1392463 exoO 3991377 exoO Escherichia coli UTI89 prophage CP-933O exonuclease VIII YP_540470.1 1389992 R 364106 CDS YP_540471.1 91210485 3991378 complement(1392556..1392756) 1 NC_007946.1 hypothetical protein 1392756 3991378 UTI89_C1460 Escherichia coli UTI89 hypothetical protein YP_540471.1 1392556 R 364106 CDS YP_540472.1 91210486 3991379 complement(1392744..1393037) 1 NC_007946.1 regulator of cell division encoded by prophage CP-933O 1393037 3991379 UTI89_C1461 Escherichia coli UTI89 regulator of cell division encoded by prophage CP-933O YP_540472.1 1392744 R 364106 CDS YP_540473.1 91210487 3991380 1393043..1393198 1 NC_007946.1 hypothetical protein 1393198 3991380 UTI89_C1462 Escherichia coli UTI89 hypothetical protein YP_540473.1 1393043 D 364106 CDS YP_540474.1 91210488 3991381 complement(1393498..1393719) 1 NC_007946.1 hypothetical protein 1393719 ydfC 3991381 ydfC Escherichia coli UTI89 hypothetical protein YP_540474.1 1393498 R 364106 CDS YP_540475.1 91210489 3991382 complement(1393749..1393919) 1 NC_007946.1 hypothetical protein 1393919 ydfB 3991382 ydfB Escherichia coli UTI89 hypothetical protein YP_540475.1 1393749 R 364106 CDS YP_540476.1 91210490 3991383 complement(1393879..1394115) 1 NC_007946.1 hypothetical protein 1394115 ydfA 3991383 ydfA Escherichia coli UTI89 hypothetical protein YP_540476.1 1393879 R 364106 CDS YP_540477.1 91210491 3991384 complement(1394327..1394965) 1 NC_007946.1 prophage CP-933O repressor protein 1394965 3991384 UTI89_C1466 Escherichia coli UTI89 prophage CP-933O repressor protein YP_540477.1 1394327 R 364106 CDS YP_540478.1 91210492 3991385 1395045..1395299 1 NC_007946.1 hypothetical protein 1395299 3991385 UTI89_C1467 Escherichia coli UTI89 hypothetical protein YP_540478.1 1395045 D 364106 CDS YP_540479.1 91210493 3991386 1395283..1395708 1 NC_007946.1 hypothetical protein 1395708 3991386 UTI89_C1468 Escherichia coli UTI89 hypothetical protein YP_540479.1 1395283 D 364106 CDS YP_540480.1 91210494 3991387 1395849..1396850 1 NC_007946.1 hypothetical protein 1396850 3991387 UTI89_C1469 Escherichia coli UTI89 hypothetical protein YP_540480.1 1395849 D 364106 CDS YP_540481.1 91210495 3990257 1396891..1397313 1 NC_007946.1 prophage hypothetical protein 1397313 3990257 UTI89_C1470 Escherichia coli UTI89 prophage hypothetical protein YP_540481.1 1396891 D 364106 CDS YP_540482.1 91210496 3990258 1397376..1398467 1 NC_007946.1 hypothetical protein 1398467 3990258 UTI89_C1471 Escherichia coli UTI89 hypothetical protein YP_540482.1 1397376 D 364106 CDS YP_540483.1 91210497 3990259 1398483..1399484 1 NC_007946.1 hypothetical protein 1399484 3990259 UTI89_C1472 Escherichia coli UTI89 hypothetical protein YP_540483.1 1398483 D 364106 CDS YP_540484.1 91210498 3990260 1399596..1399886 1 NC_007946.1 hypothetical protein 1399886 3990260 UTI89_C1473 Escherichia coli UTI89 hypothetical protein YP_540484.1 1399596 D 364106 CDS YP_540485.1 91210499 3990261 1400045..1400257 1 NC_007946.1 cryptic prophage CP-933M cell killing protein 1400257 3990261 UTI89_C1474 Escherichia coli UTI89 cryptic prophage CP-933M cell killing protein YP_540485.1 1400045 D 364106 CDS YP_540486.1 91210500 3990262 1400425..1400703 1 NC_007946.1 hypothetical protein 1400703 3990262 UTI89_C1475 Escherichia coli UTI89 hypothetical protein YP_540486.1 1400425 D 364106 CDS YP_540487.1 91210501 3990263 1400705..1401751 1 NC_007946.1 hypothetical protein 1401751 3990263 UTI89_C1476 Escherichia coli UTI89 hypothetical protein YP_540487.1 1400705 D 364106 CDS YP_540489.1 91210503 3990265 1401764..1402138 1 NC_007946.1 endodeoxyribonuclease RusA 1402138 3990265 UTI89_C1478 Escherichia coli UTI89 endodeoxyribonuclease RusA YP_540489.1 1401764 D 364106 CDS YP_540490.1 91210504 3990266 1402135..1402956 1 NC_007946.1 cryptic prophage CP-933M antitermination protein Q-like protein 1402956 3990266 UTI89_C1479 Escherichia coli UTI89 cryptic prophage CP-933M antitermination protein Q-like protein YP_540490.1 1402135 D 364106 CDS YP_540491.1 91210505 3990267 1403181..1403378 1 NC_007946.1 hypothetical protein 1403378 3990267 UTI89_C1480 Escherichia coli UTI89 hypothetical protein YP_540491.1 1403181 D 364106 CDS YP_540492.1 91210506 3990268 1403529..1404578 1 NC_007946.1 prophage CP-933O DNA adenine methyltransferase 1404578 3990268 UTI89_C1481 Escherichia coli UTI89 prophage CP-933O DNA adenine methyltransferase YP_540492.1 1403529 D 364106 CDS YP_540493.1 91210507 3990271 1405049..1405312 1 NC_007946.1 hypothetical protein 1405312 3990271 UTI89_C1484 Escherichia coli UTI89 hypothetical protein YP_540493.1 1405049 D 364106 CDS YP_540494.1 91210508 3990272 1405853..1406080 1 NC_007946.1 hypothetical protein 1406080 3990272 UTI89_C1485 Escherichia coli UTI89 hypothetical protein YP_540494.1 1405853 D 364106 CDS YP_540495.1 91210509 3990273 1406038..1406199 1 NC_007946.1 hypothetical protein 1406199 3990273 UTI89_C1486 Escherichia coli UTI89 hypothetical protein YP_540495.1 1406038 D 364106 CDS YP_540496.1 91210510 3990274 1406244..1406564 1 NC_007946.1 lambdoid prophage DLP12 lysis protein S-like protein 1406564 3990274 UTI89_C1487 Escherichia coli UTI89 lambdoid prophage DLP12 lysis protein S-like protein YP_540496.1 1406244 D 364106 CDS YP_540497.1 91210511 3994005 1406569..1406913 1 NC_007946.1 hypothetical protein 1406913 ydfR 3994005 ydfR Escherichia coli UTI89 hypothetical protein YP_540497.1 1406569 D 364106 CDS YP_540498.1 91210512 3994006 complement(1406879..1407151) 1 NC_007946.1 hypothetical protein 1407151 3994006 UTI89_C1489 Escherichia coli UTI89 hypothetical protein YP_540498.1 1406879 R 364106 CDS YP_540499.1 91210513 3994007 1407257..1407790 1 NC_007946.1 phage lysozyme 1407790 3994007 UTI89_C1490 Escherichia coli UTI89 phage lysozyme YP_540499.1 1407257 D 364106 CDS YP_540500.1 91210514 3994008 1407914..1408087 1 NC_007946.1 hypothetical protein 1408087 3994008 UTI89_C1491 Escherichia coli UTI89 hypothetical protein YP_540500.1 1407914 D 364106 CDS YP_540501.1 91210515 3994009 1408089..1408553 1 NC_007946.1 bacteriophage lambda cell lysis protein 1408553 3994009 UTI89_C1492 Escherichia coli UTI89 bacteriophage lambda cell lysis protein YP_540501.1 1408089 D 364106 CDS YP_540502.1 91210516 3994010 complement(1408861..1409286) 1 NC_007946.1 hypothetical protein 1409286 ydfO 3994010 ydfO Escherichia coli UTI89 hypothetical protein YP_540502.1 1408861 R 364106 CDS YP_540503.1 91210517 3994011 complement(1409329..1409562) 1 NC_007946.1 prophage hypothetical protein 1409562 3994011 UTI89_C1494 Escherichia coli UTI89 prophage hypothetical protein YP_540503.1 1409329 R 364106 CDS YP_540504.1 91210518 3994012 1409710..1409868 1 NC_007946.1 hypothetical protein 1409868 3994012 UTI89_C1495 Escherichia coli UTI89 hypothetical protein YP_540504.1 1409710 D 364106 CDS YP_540505.1 91210519 3994013 1409949..1410497 1 NC_007946.1 prophage Qin DNA packaging protein NU1-like protein 1410497 nohA2 3994013 nohA2 Escherichia coli UTI89 prophage Qin DNA packaging protein NU1-like protein YP_540505.1 1409949 D 364106 CDS YP_540506.1 91210520 3994014 1410445..1412397 1 NC_007946.1 prophage DNA packaging protein terminase large subunit 1412397 3994014 UTI89_C1497 Escherichia coli UTI89 prophage DNA packaging protein terminase large subunit YP_540506.1 1410445 D 364106 CDS YP_540507.1 91210521 3994015 1412381..1412587 1 NC_007946.1 prophage DNA packaging protein 1412587 3994015 UTI89_C1498 Escherichia coli UTI89 prophage DNA packaging protein YP_540507.1 1412381 D 364106 CDS YP_540508.1 91210522 3994016 1412584..1414176 1 NC_007946.1 prophage capsid protein 1414176 3994016 UTI89_C1499 Escherichia coli UTI89 prophage capsid protein YP_540508.1 1412584 D 364106 CDS YP_540509.1 91210523 3994017 1414166..1415671 1 NC_007946.1 prophage capsid assembly protein 1415671 3994017 UTI89_C1500 Escherichia coli UTI89 prophage capsid assembly protein YP_540509.1 1414166 D 364106 CDS YP_540510.1 91210524 3994018 1415708..1416055 1 NC_007946.1 capsid protein small subunit 1416055 3994018 UTI89_C1501 Escherichia coli UTI89 capsid protein small subunit YP_540510.1 1415708 D 364106 CDS YP_540511.1 91210525 3994019 1416113..1417141 1 NC_007946.1 prophage capsid protein 1417141 3994019 UTI89_C1502 Escherichia coli UTI89 prophage capsid protein YP_540511.1 1416113 D 364106 CDS YP_540512.1 91210526 3994020 1417145..1417576 1 NC_007946.1 hypothetical protein 1417576 3994020 UTI89_C1503 Escherichia coli UTI89 hypothetical protein YP_540512.1 1417145 D 364106 CDS YP_540513.1 91210527 3994021 1417569..1417922 1 NC_007946.1 prophage head-tail joining protein 1417922 3994021 UTI89_C1504 Escherichia coli UTI89 prophage head-tail joining protein YP_540513.1 1417569 D 364106 CDS YP_540514.1 91210528 3994022 1417938..1418471 1 NC_007946.1 minor tail protein 1418471 3994022 UTI89_C1505 Escherichia coli UTI89 minor tail protein YP_540514.1 1417938 D 364106 CDS YP_540515.1 91210529 3994023 1418468..1418863 1 NC_007946.1 prophage tail component 1418863 3994023 UTI89_C1506 Escherichia coli UTI89 prophage tail component YP_540515.1 1418468 D 364106 CDS YP_540516.1 91210530 3990480 1418871..1419623 1 NC_007946.1 tail fiber component V of prophage CP-933U 1419623 3990480 UTI89_C1507 Escherichia coli UTI89 tail fiber component V of prophage CP-933U YP_540516.1 1418871 D 364106 CDS YP_540517.1 91210531 3990481 1419637..1420068 1 NC_007946.1 prophage tail component 1420068 3990481 UTI89_C1508 Escherichia coli UTI89 prophage tail component YP_540517.1 1419637 D 364106 CDS YP_540518.1 91210532 3990482 1420095..1420508 1 NC_007946.1 tail component of prophage CP-933O 1420508 3990482 UTI89_C1509 Escherichia coli UTI89 tail component of prophage CP-933O YP_540518.1 1420095 D 364106 CDS YP_540519.1 91210533 3990483 1420489..1423062 1 NC_007946.1 tail component of prophage CP-933O 1423062 3990483 UTI89_C1510 Escherichia coli UTI89 tail component of prophage CP-933O YP_540519.1 1420489 D 364106 CDS YP_540520.1 91210534 3990484 1423059..1423388 1 NC_007946.1 minor tail protein 1423388 3990484 UTI89_C1511 Escherichia coli UTI89 minor tail protein YP_540520.1 1423059 D 364106 CDS YP_540521.1 91210535 3990485 complement(1423292..1424092) 1 NC_007946.1 hypothetical protein 1424092 3990485 UTI89_C1512 Escherichia coli UTI89 hypothetical protein YP_540521.1 1423292 R 364106 CDS YP_540522.1 91210536 3990486 1423388..1424086 1 NC_007946.1 minor tail protein 1424086 3990486 UTI89_C1513 Escherichia coli UTI89 minor tail protein YP_540522.1 1423388 D 364106 CDS YP_540523.1 91210537 3990487 1424049..1424834 1 NC_007946.1 prophage tail fiber component K 1424834 3990487 UTI89_C1514 Escherichia coli UTI89 prophage tail fiber component K YP_540523.1 1424049 D 364106 CDS YP_540524.1 91210538 3990488 1424732..1425373 1 NC_007946.1 tail component of prophage CP-933K 1425373 3990488 UTI89_C1515 Escherichia coli UTI89 tail component of prophage CP-933K YP_540524.1 1424732 D 364106 CDS YP_540525.1 91210539 3990489 1425447..1425785 1 NC_007946.1 hypothetical protein 1425785 3990489 UTI89_C1516 Escherichia coli UTI89 hypothetical protein YP_540525.1 1425447 D 364106 CDS YP_540526.1 91210540 3990490 1425852..1429331 1 NC_007946.1 prophage tail component 1429331 3990490 UTI89_C1517 Escherichia coli UTI89 prophage tail component YP_540526.1 1425852 D 364106 CDS YP_540527.1 91210541 3990491 1429399..1429998 1 NC_007946.1 hypothetical protein 1429998 3990491 UTI89_C1518 Escherichia coli UTI89 hypothetical protein YP_540527.1 1429399 D 364106 CDS YP_540528.1 91210542 3990492 1430150..1433257 1 NC_007946.1 tail fiber protein 1433257 3990492 UTI89_C1519 Escherichia coli UTI89 tail fiber protein YP_540528.1 1430150 D 364106 CDS YP_540529.1 91210543 3990493 complement(1430647..1431396) 1 NC_007946.1 hypothetical protein 1431396 3990493 UTI89_C1520 Escherichia coli UTI89 hypothetical protein YP_540529.1 1430647 R 364106 CDS YP_540530.1 91210544 3990494 1433257..1433841 1 NC_007946.1 phage-related tail fiber assembly protein G 1433841 ynaC 3990494 ynaC Escherichia coli UTI89 phage-related tail fiber assembly protein G YP_540530.1 1433257 D 364106 CDS YP_540531.1 91210545 3990495 complement(1433896..1434561) 1 NC_007946.1 hypothetical protein 1434561 3990495 UTI89_C1522 Escherichia coli UTI89 hypothetical protein YP_540531.1 1433896 R 364106 CDS YP_540532.1 91210546 3990496 1434621..1434890 1 NC_007946.1 hypothetical protein 1434890 ylcE 3990496 ylcE Escherichia coli UTI89 hypothetical protein YP_540532.1 1434621 D 364106 CDS YP_540533.1 91210547 3990497 complement(1434710..1435048) 1 NC_007946.1 hypothetical protein 1435048 3990497 UTI89_C1524 Escherichia coli UTI89 hypothetical protein YP_540533.1 1434710 R 364106 CDS YP_540534.1 91210548 3990498 1434894..1435175 1 NC_007946.1 hypothetical protein 1435175 3990498 UTI89_C1525 Escherichia coli UTI89 hypothetical protein YP_540534.1 1434894 D 364106 CDS YP_540535.1 91210549 3990499 complement(1435663..1436169) 1 NC_007946.1 hypothetical protein 1436169 yciE 3990499 yciE Escherichia coli UTI89 hypothetical protein YP_540535.1 1435663 R 364106 CDS YP_540536.1 91210550 3990057 complement(1436215..1436715) 1 NC_007946.1 structural proteins 1436715 yciF 3990057 yciF Escherichia coli UTI89 structural proteins YP_540536.1 1436215 R 364106 CDS YP_540537.1 91210551 3990058 complement(1436801..1437037) 1 NC_007946.1 hypothetical protein 1437037 yciG 3990058 yciG Escherichia coli UTI89 hypothetical protein YP_540537.1 1436801 R 364106 CDS YP_540538.1 91210552 3990059 complement(1437361..1438167) 1 NC_007946.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1438167 trpA 3990059 trpA Escherichia coli UTI89 tryptophan synthase subunit alpha YP_540538.1 1437361 R 364106 CDS YP_540539.1 91210553 3990060 complement(1438167..1439360) 1 NC_007946.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1439360 trpB 3990060 trpB Escherichia coli UTI89 tryptophan synthase subunit beta YP_540539.1 1438167 R 364106 CDS YP_540540.1 91210554 3990061 complement(1439372..1440730) 1 NC_007946.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1440730 trpC 3990061 trpC Escherichia coli UTI89 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_540540.1 1439372 R 364106 CDS YP_540541.1 91210555 3990062 complement(1440734..1442329) 1 NC_007946.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1442329 trpD 3990062 trpD Escherichia coli UTI89 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_540541.1 1440734 R 364106 CDS YP_540542.1 91210556 3990063 complement(1442329..1443891) 1 NC_007946.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1443891 trpE 3990063 trpE Escherichia coli UTI89 anthranilate synthase component I YP_540542.1 1442329 R 364106 CDS YP_540543.1 91210557 3990064 1444165..1445046 1 NC_007946.1 hypothetical protein 1445046 trpH 3990064 trpH Escherichia coli UTI89 hypothetical protein YP_540543.1 1444165 D 364106 CDS YP_540544.1 91210558 3990065 1445007..1445663 1 NC_007946.1 hypothetical protein 1445663 yciO 3990065 yciO Escherichia coli UTI89 hypothetical protein YP_540544.1 1445007 D 364106 CDS YP_540545.1 91210559 3990066 1445688..1447586 1 NC_007946.1 hypothetical protein 1447586 yciQ 3990066 yciQ Escherichia coli UTI89 hypothetical protein YP_540545.1 1445688 D 364106 CDS YP_540546.1 91210560 3990067 1447799..1448674 1 NC_007946.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1448674 yciL 3990067 yciL Escherichia coli UTI89 23S rRNA pseudouridylate synthase B YP_540546.1 1447799 D 364106 CDS YP_540547.1 91210561 3990068 complement(1448714..1449304) 1 NC_007946.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1449304 btuR 3990068 btuR Escherichia coli UTI89 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_540547.1 1448714 R 364106 CDS YP_540548.1 91210562 3990069 complement(1449301..1450059) 1 NC_007946.1 short chain dehydrogenase 1450059 yciK 3990069 yciK Escherichia coli UTI89 short chain dehydrogenase YP_540548.1 1449301 R 364106 CDS YP_540549.1 91210563 3990070 1450279..1451328 1 NC_007946.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1451328 sohB 3990070 sohB Escherichia coli UTI89 periplasmic protease YP_540549.1 1450279 D 364106 CDS YP_540550.1 91210564 3990071 complement(1451364..1451615) 1 NC_007946.1 hypothetical protein 1451615 yciN 3990071 yciN Escherichia coli UTI89 hypothetical protein YP_540550.1 1451364 R 364106 CDS YP_540551.1 91210565 3990072 1451608..1451763 1 NC_007946.1 hypothetical protein 1451763 3990072 UTI89_C1542 Escherichia coli UTI89 hypothetical protein YP_540551.1 1451608 D 364106 CDS YP_540552.1 91210566 3990073 1451953..1454592 1 NC_007946.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1454592 topA 3990073 topA Escherichia coli UTI89 DNA topoisomerase I YP_540552.1 1451953 D 364106 CDS YP_540553.1 91210567 3990074 1454802..1455776 1 NC_007946.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1455776 cysB 3990074 cysB Escherichia coli UTI89 transcriptional regulator CysB YP_540553.1 1454802 D 364106 CDS YP_540554.1 91210568 3990075 1456071..1456235 1 NC_007946.1 hypothetical protein 1456235 3990075 UTI89_C1545 Escherichia coli UTI89 hypothetical protein YP_540554.1 1456071 D 364106 CDS YP_540555.1 91210569 3994116 1456217..1456405 1 NC_007946.1 hypothetical protein 1456405 3994116 UTI89_C1546 Escherichia coli UTI89 hypothetical protein YP_540555.1 1456217 D 364106 CDS YP_540556.1 91210570 3994117 1456764..1459439 1 NC_007946.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1459439 acnA 3994117 acnA Escherichia coli UTI89 aconitate hydratase YP_540556.1 1456764 D 364106 CDS YP_540557.1 91210571 3994118 complement(1459503..1460156) 1 NC_007946.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1460156 ribA 3994118 ribA Escherichia coli UTI89 GTP cyclohydrolase II YP_540557.1 1459503 R 364106 CDS YP_540558.1 91210572 3994119 1460263..1461027 1 NC_007946.1 phosphatidylglycerophosphatase B 1461027 pgpB 3994119 pgpB Escherichia coli UTI89 phosphatidylglycerophosphatase B YP_540558.1 1460263 D 364106 CDS YP_540559.1 91210573 3994120 1461176..1461484 1 NC_007946.1 hypothetical protein 1461484 yciS 3994120 yciS Escherichia coli UTI89 hypothetical protein YP_540559.1 1461176 D 364106 CDS YP_540560.1 91210574 3994121 1461491..1462660 1 NC_007946.1 tetratricopeptide repeat protein 1462660 yciM 3994121 yciM Escherichia coli UTI89 tetratricopeptide repeat protein YP_540560.1 1461491 D 364106 CDS YP_540561.1 91210575 3994122 1462851..1463588 1 NC_007946.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1463588 pyrF 3994122 pyrF Escherichia coli UTI89 orotidine 5'-phosphate decarboxylase YP_540561.1 1462851 D 364106 CDS YP_540562.1 91210576 3994123 1463588..1463914 1 NC_007946.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1463914 yciH 3994123 yciH Escherichia coli UTI89 translation initiation factor Sui1 YP_540562.1 1463588 D 364106 CDS YP_540563.1 91210577 3994124 1463938..1464090 1 NC_007946.1 hypothetical protein 1464090 3994124 UTI89_C1554 Escherichia coli UTI89 hypothetical protein YP_540563.1 1463938 D 364106 CDS YP_540564.1 91210578 3994125 complement(1464040..1464258) 1 NC_007946.1 lipoprotein 1464258 osmB 3994125 osmB Escherichia coli UTI89 lipoprotein YP_540564.1 1464040 R 364106 CDS YP_540565.1 91210579 3994126 complement(1464527..1465276) 1 NC_007946.1 DEOR-type transcriptional regulator 1465276 3994126 UTI89_C1556 Escherichia coli UTI89 DEOR-type transcriptional regulator YP_540565.1 1464527 R 364106 CDS YP_540566.1 91210580 3994127 complement(1465366..1465539) 1 NC_007946.1 hypothetical protein 1465539 3994127 UTI89_C1557 Escherichia coli UTI89 hypothetical protein YP_540566.1 1465366 R 364106 CDS YP_540567.1 91210581 3994128 complement(1465687..1467672) 1 NC_007946.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1467672 yciR 3994128 yciR Escherichia coli UTI89 RNase II stability modulator YP_540567.1 1465687 R 364106 CDS YP_540568.1 91210582 3994129 complement(1467906..1469840) 1 NC_007946.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1469840 rnb 3994129 rnb Escherichia coli UTI89 exoribonuclease II YP_540568.1 1467906 R 364106 CDS YP_540569.1 91210583 3994130 complement(1469908..1471113) 1 NC_007946.1 hypothetical protein 1471113 yciW 3994130 yciW Escherichia coli UTI89 hypothetical protein YP_540569.1 1469908 R 364106 CDS YP_540570.1 91210584 3994131 complement(1471180..1471968) 1 NC_007946.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1471968 fabI 3994131 fabI Escherichia coli UTI89 enoyl-ACP reductase YP_540570.1 1471180 R 364106 CDS YP_540571.1 91210585 3994132 1472347..1473012 1 NC_007946.1 transcriptional repressor 1473012 3994132 UTI89_C1562 Escherichia coli UTI89 transcriptional repressor YP_540571.1 1472347 D 364106 CDS YP_540572.1 91210586 3994133 1473128..1474282 1 NC_007946.1 acriflavine resistance protein A 1474282 3994133 UTI89_C1563 Escherichia coli UTI89 acriflavine resistance protein A YP_540572.1 1473128 D 364106 CDS YP_540573.1 91210587 3994134 1474282..1477389 1 NC_007946.1 acriflavine resistance protein B 1477389 3994134 UTI89_C1564 Escherichia coli UTI89 acriflavine resistance protein B YP_540573.1 1474282 D 364106 CDS YP_540574.1 91210588 3994135 1477393..1478766 1 NC_007946.1 outer membrane channel protein 1478766 3994135 UTI89_C1565 Escherichia coli UTI89 outer membrane channel protein YP_540574.1 1477393 D 364106 CDS YP_540575.1 91210589 3994588 1478775..1479938 1 NC_007946.1 membrane transport protein 1479938 3994588 UTI89_C1566 Escherichia coli UTI89 membrane transport protein YP_540575.1 1478775 D 364106 CDS YP_540576.1 91210590 3994589 complement(1479986..1480792) 1 NC_007946.1 peptide transport system ATP-binding protein SapF 1480792 sapF 3994589 sapF Escherichia coli UTI89 peptide transport system ATP-binding protein SapF YP_540576.1 1479986 R 364106 CDS YP_540577.1 91210591 3994590 complement(1480794..1481786) 1 NC_007946.1 peptide ABC transporter ATP-binding protein 1481786 sapD 3994590 sapD Escherichia coli UTI89 peptide ABC transporter ATP-binding protein YP_540577.1 1480794 R 364106 CDS YP_540578.1 91210592 3994591 complement(1481786..1482676) 1 NC_007946.1 peptide transport system permease SapC 1482676 sapC 3994591 sapC Escherichia coli UTI89 peptide transport system permease SapC YP_540578.1 1481786 R 364106 CDS YP_540579.1 91210593 3994592 complement(1482663..1483628) 1 NC_007946.1 peptide transport system permease SapB 1483628 sapB 3994592 sapB Escherichia coli UTI89 peptide transport system permease SapB YP_540579.1 1482663 R 364106 CDS YP_540580.1 91210594 3994593 complement(1483625..1485268) 1 NC_007946.1 peptide transport periplasmic protein SapA 1485268 sapA 3994593 sapA Escherichia coli UTI89 peptide transport periplasmic protein SapA YP_540580.1 1483625 R 364106 CDS YP_540581.1 91210595 3994594 complement(1485581..1485826) 1 NC_007946.1 hypothetical protein 1485826 ymjA 3994594 ymjA Escherichia coli UTI89 hypothetical protein YP_540581.1 1485581 R 364106 CDS YP_540582.2 162138445 3994595 complement(1486253..1487230) 1 NC_007946.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1487230 pspF 3994595 pspF Escherichia coli UTI89 phage shock protein operon transcriptional activator YP_540582.2 1486253 R 364106 CDS YP_540583.1 91210597 3994596 1487396..1488064 1 NC_007946.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1488064 pspA 3994596 pspA Escherichia coli UTI89 phage shock protein PspA YP_540583.1 1487396 D 364106 CDS YP_540584.1 91210598 3994597 1488118..1488342 1 NC_007946.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1488342 pspB 3994597 pspB Escherichia coli UTI89 phage shock protein B YP_540584.1 1488118 D 364106 CDS YP_540585.1 91210599 3994598 1488342..1488701 1 NC_007946.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1488701 pspC 3994598 pspC Escherichia coli UTI89 DNA-binding transcriptional activator PspC YP_540585.1 1488342 D 364106 CDS YP_540586.1 91210600 3994599 1488710..1488931 1 NC_007946.1 peripheral inner membrane phage-shock protein 1488931 pspD 3994599 pspD Escherichia coli UTI89 peripheral inner membrane phage-shock protein YP_540586.1 1488710 D 364106 CDS YP_540587.1 91210601 3994600 1489006..1489320 1 NC_007946.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1489320 pspE 3994600 pspE Escherichia coli UTI89 thiosulfate:cyanide sulfurtransferase YP_540587.1 1489006 D 364106 CDS YP_540588.1 91210602 3994601 1489503..1491209 1 NC_007946.1 sucrose phosphorylase 1491209 ycjM 3994601 ycjM Escherichia coli UTI89 sucrose phosphorylase YP_540588.1 1489503 D 364106 CDS YP_540589.1 91210603 3994602 complement(1491024..1491224) 1 NC_007946.1 hypothetical protein 1491224 3994602 UTI89_C1580 Escherichia coli UTI89 hypothetical protein YP_540589.1 1491024 R 364106 CDS YP_540590.1 91210604 3994603 1491223..1492515 1 NC_007946.1 ABC transporter periplasmic binding protein ycjN 1492515 ycjN 3994603 ycjN Escherichia coli UTI89 ABC transporter periplasmic binding protein ycjN YP_540590.1 1491223 D 364106 CDS YP_540591.1 91210605 3994604 1492536..1493417 1 NC_007946.1 binding-protein dependent transport protein 1493417 ycjO 3994604 ycjO Escherichia coli UTI89 binding-protein dependent transport protein YP_540591.1 1492536 D 364106 CDS YP_540592.1 91210606 3994605 1493404..1494246 1 NC_007946.1 ABC transporter permease 1494246 ycjP 3994605 ycjP Escherichia coli UTI89 ABC transporter permease YP_540592.1 1493404 D 364106 CDS YP_540593.1 91210607 3994606 1494277..1495329 1 NC_007946.1 zinc-type alcohol dehydrogenase-like protein YcjQ 1495329 ycjQ 3994606 ycjQ Escherichia coli UTI89 zinc-type alcohol dehydrogenase-like protein YcjQ YP_540593.1 1494277 D 364106 CDS YP_540594.1 91210608 3994233 1495339..1496136 1 NC_007946.1 hypothetical protein 1496136 ycjR 3994233 ycjR Escherichia coli UTI89 hypothetical protein YP_540594.1 1495339 D 364106 CDS YP_540595.1 91210609 3994234 1496146..1497201 1 NC_007946.1 oxidoreductase YcjS 1497201 ycjS 3994234 ycjS Escherichia coli UTI89 oxidoreductase YcjS YP_540595.1 1496146 D 364106 CDS YP_540596.1 91210610 3994235 1497198..1499465 1 NC_007946.1 transport protein YcjT 1499465 ycjT 3994235 ycjT Escherichia coli UTI89 transport protein YcjT YP_540596.1 1497198 D 364106 CDS YP_540597.1 91210611 3994236 1499462..1500121 1 NC_007946.1 beta-phosphoglucomutase 1500121 ycjU 3994236 ycjU Escherichia coli UTI89 beta-phosphoglucomutase YP_540597.1 1499462 D 364106 CDS YP_540598.1 91210612 3994237 1500135..1501217 1 NC_007946.1 ABC transporter ATP-binding protein 1501217 ycjV 3994237 ycjV Escherichia coli UTI89 ABC transporter ATP-binding protein YP_540598.1 1500135 D 364106 CDS YP_540599.1 91210613 3994238 1501211..1502167 1 NC_007946.1 outer membrane protein G 1502167 ompG 3994238 ompG Escherichia coli UTI89 outer membrane protein G YP_540599.1 1501211 D 364106 CDS YP_540600.1 91210614 3994239 complement(1502218..1503216) 1 NC_007946.1 transcriptional regulator YcjW 1503216 ycjW 3994239 ycjW Escherichia coli UTI89 transcriptional regulator YcjW YP_540600.1 1502218 R 364106 CDS YP_540601.1 91210615 3994240 1503300..1504769 1 NC_007946.1 hypothetical protein 1504769 ycjX 3994240 ycjX Escherichia coli UTI89 hypothetical protein YP_540601.1 1503300 D 364106 CDS YP_540602.1 91210616 3994241 1504766..1505827 1 NC_007946.1 hypothetical protein 1505827 ycjF 3994241 ycjF Escherichia coli UTI89 hypothetical protein YP_540602.1 1504766 D 364106 CDS YP_540603.1 91210617 3994242 1505948..1507516 1 NC_007946.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1507516 tyrR 3994242 tyrR Escherichia coli UTI89 DNA-binding transcriptional regulator TyrR YP_540603.1 1505948 D 364106 CDS YP_540604.1 91210618 3994243 complement(1507560..1508066) 1 NC_007946.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1508066 tpx 3994243 tpx Escherichia coli UTI89 thiol peroxidase YP_540604.1 1507560 R 364106 CDS YP_540605.1 91210619 3994244 1508185..1509150 1 NC_007946.1 hypothetical protein 1509150 ycjG 3994244 ycjG Escherichia coli UTI89 hypothetical protein YP_540605.1 1508185 D 364106 CDS YP_540606.1 91210620 3994245 complement(1509125..1509913) 1 NC_007946.1 murein peptide amidase A 1509913 ycjI 3994245 ycjI Escherichia coli UTI89 murein peptide amidase A YP_540606.1 1509125 R 364106 CDS YP_540607.1 91210621 3994246 complement(1510144..1510782) 1 NC_007946.1 hypothetical protein 1510782 3994246 UTI89_C1598 Escherichia coli UTI89 hypothetical protein YP_540607.1 1510144 R 364106 CDS YP_540608.1 91210622 3994247 complement(1510853..1511785) 1 NC_007946.1 hypothetical protein 1511785 3994247 UTI89_C1599 Escherichia coli UTI89 hypothetical protein YP_540608.1 1510853 R 364106 CDS YP_540609.1 91210623 3994248 1511911..1512810 1 NC_007946.1 transcriptional regulator YcjZ 1512810 3994248 UTI89_C1600 Escherichia coli UTI89 transcriptional regulator YcjZ YP_540609.1 1511911 D 364106 CDS YP_540610.1 91210624 3994249 1513126..1514760 1 NC_007946.1 periplasmic murein peptide-binding protein 1514760 mppA 3994249 mppA Escherichia coli UTI89 periplasmic murein peptide-binding protein YP_540610.1 1513126 D 364106 CDS YP_540611.1 91210625 3994250 complement(1514811..1515842) 1 NC_007946.1 hypothetical protein 1515842 ynaI 3994250 ynaI Escherichia coli UTI89 hypothetical protein YP_540611.1 1514811 R 364106 CDS YP_540612.1 91210626 3994251 1516086..1516343 1 NC_007946.1 hypothetical protein 1516343 ynaJ 3994251 ynaJ Escherichia coli UTI89 hypothetical protein YP_540612.1 1516086 D 364106 CDS YP_540613.1 91210627 3994252 complement(1516393..1517343) 1 NC_007946.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1517343 ydaA 3994252 ydaA Escherichia coli UTI89 universal stress protein UspE YP_540613.1 1516393 R 364106 CDS YP_540614.2 162138444 3992010 complement(1517495..1518247) 1 NC_007946.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1518247 fnr 3992010 fnr Escherichia coli UTI89 fumarate/nitrate reduction transcriptional regulator YP_540614.2 1517495 R 364106 CDS YP_540615.1 91210629 3992011 complement(1518442..1518957) 1 NC_007946.1 O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1518957 ogt 3992011 ogt Escherichia coli UTI89 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_540615.1 1518442 R 364106 CDS YP_540616.1 91210630 3992012 complement(1518968..1519159) 1 NC_007946.1 hypothetical protein 1519159 3992012 UTI89_C1607 Escherichia coli UTI89 hypothetical protein YP_540616.1 1518968 R 364106 CDS YP_540617.1 91210631 3992013 complement(1519489..1520304) 1 NC_007946.1 hypothetical protein 1520304 3992013 UTI89_C1608 Escherichia coli UTI89 hypothetical protein YP_540617.1 1519489 R 364106 CDS YP_540618.1 91210632 3992014 1520401..1521429 1 NC_007946.1 secretion protein 1521429 3992014 UTI89_C1609 Escherichia coli UTI89 secretion protein YP_540618.1 1520401 D 364106 CDS YP_540619.1 91210633 3992015 1521426..1522940 1 NC_007946.1 transporter 1522940 3992015 UTI89_C1610 Escherichia coli UTI89 transporter YP_540619.1 1521426 D 364106 CDS YP_540620.1 91210634 3992016 1523135..1523698 1 NC_007946.1 hypothetical protein 1523698 ydaL 3992016 ydaL Escherichia coli UTI89 hypothetical protein YP_540620.1 1523135 D 364106 CDS YP_540621.1 91210635 3992017 complement(1523719..1525011) 1 NC_007946.1 hypothetical protein 1525011 ydaM 3992017 ydaM Escherichia coli UTI89 hypothetical protein YP_540621.1 1523719 R 364106 CDS YP_540622.1 91210636 3992018 1525206..1526189 1 NC_007946.1 zinc transporter 1526189 zntB 3992018 zntB Escherichia coli UTI89 zinc transporter YP_540622.1 1525206 D 364106 CDS YP_540623.1 91210637 3992019 1526667..1528040 1 NC_007946.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1528040 dbpA 3992019 dbpA Escherichia coli UTI89 ATP-dependent RNA helicase DbpA YP_540623.1 1526667 D 364106 CDS YP_540624.1 91210638 3992020 complement(1528169..1529104) 1 NC_007946.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1529104 ydaO 3992020 ydaO Escherichia coli UTI89 C32 tRNA thiolase YP_540624.1 1528169 R 364106 CDS YP_540625.1 91210639 3992021 complement(1529156..1529464) 1 NC_007946.1 hypothetical protein 1529464 3992021 UTI89_C1616 Escherichia coli UTI89 hypothetical protein YP_540625.1 1529156 R 364106 CDS YP_540626.1 91210640 3992022 complement(1531431..1531937) 1 NC_007946.1 hypothetical protein 1531937 ynaF 3992022 ynaF Escherichia coli UTI89 hypothetical protein YP_540626.1 1531431 R 364106 CDS YP_540627.1 91210641 3992023 complement(1532006..1533139) 1 NC_007946.1 outer membrane protein N 1533139 ompN 3992023 ompN Escherichia coli UTI89 outer membrane protein N YP_540627.1 1532006 R 364106 CDS YP_540628.1 91210642 3992024 complement(1533505..1537029) 1 NC_007946.1 pyruvate-flavodoxin oxidoreductase 1537029 ydbK 3992024 ydbK Escherichia coli UTI89 pyruvate-flavodoxin oxidoreductase YP_540628.1 1533505 R 364106 CDS YP_540629.1 91210643 3992025 complement(1537100..1537435) 1 NC_007946.1 hypothetical protein 1537435 3992025 UTI89_C1620 Escherichia coli UTI89 hypothetical protein YP_540629.1 1537100 R 364106 CDS YP_540630.1 91210644 3992026 1537303..1537569 1 NC_007946.1 hypothetical protein 1537569 3992026 UTI89_C1621 Escherichia coli UTI89 hypothetical protein YP_540630.1 1537303 D 364106 CDS YP_540631.1 91210645 3992027 complement(1537566..1538000) 1 NC_007946.1 heat-inducible protein 1538000 hslJ 3992027 hslJ Escherichia coli UTI89 heat-inducible protein YP_540631.1 1537566 R 364106 CDS YP_540632.1 91210646 3992028 complement(1538099..1539088) 1 NC_007946.1 D-lactate dehydrogenase 1539088 ldhA 3992028 ldhA Escherichia coli UTI89 D-lactate dehydrogenase YP_540632.1 1538099 R 364106 CDS YP_540633.1 91210647 3991853 1539296..1541935 1 NC_007946.1 hypothetical protein 1541935 ydbH 3991853 ydbH Escherichia coli UTI89 hypothetical protein YP_540633.1 1539296 D 364106 CDS YP_540634.1 91210648 3991854 1541932..1542117 1 NC_007946.1 hypothetical protein 1542117 ynbE 3991854 ynbE Escherichia coli UTI89 hypothetical protein YP_540634.1 1541932 D 364106 CDS YP_540635.1 91210649 3991855 1542092..1542451 1 NC_007946.1 hypothetical protein 1542451 ydbL 3991855 ydbL Escherichia coli UTI89 hypothetical protein YP_540635.1 1542092 D 364106 CDS YP_540636.1 91210650 3991856 1542827..1551142 1 NC_007946.1 EntS/YbdA MFS transporter 1551142 entS 3991856 entS Escherichia coli UTI89 EntS/YbdA MFS transporter YP_540636.1 1542827 D 364106 CDS YP_540637.1 91210651 3991857 1551362..1552222 1 NC_007946.1 oxidoreductase 1552222 3991857 UTI89_C1628 Escherichia coli UTI89 oxidoreductase YP_540637.1 1551362 D 364106 CDS YP_540638.1 91210652 3991858 complement(1552267..1552491) 1 NC_007946.1 hypothetical protein 1552491 3991858 UTI89_C1629 Escherichia coli UTI89 hypothetical protein YP_540638.1 1552267 R 364106 CDS YP_540639.1 91210653 3991859 1552521..1553126 1 NC_007946.1 hypothetical protein 1553126 ynbA 3991859 ynbA Escherichia coli UTI89 hypothetical protein YP_540639.1 1552521 D 364106 CDS YP_540640.1 91210654 3991860 1553126..1554022 1 NC_007946.1 phosphatidate cytidiltransferase 1554022 ynbB 3991860 ynbB Escherichia coli UTI89 phosphatidate cytidiltransferase YP_540640.1 1553126 D 364106 CDS YP_540641.1 91210655 3991861 1554038..1555795 1 NC_007946.1 methylase 1555795 ynbC 3991861 ynbC Escherichia coli UTI89 methylase YP_540641.1 1554038 D 364106 CDS YP_540642.1 91210656 3991862 1555710..1557101 1 NC_007946.1 hypothetical protein 1557101 ynbD 3991862 ynbD Escherichia coli UTI89 hypothetical protein YP_540642.1 1555710 D 364106 CDS YP_540643.1 91210657 3991863 complement(1557155..1557760) 1 NC_007946.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1557760 acpD 3991863 acpD Escherichia coli UTI89 azoreductase YP_540643.1 1557155 R 364106 CDS YP_540644.2 162138443 3991864 1558018..1561863 1 NC_007946.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1561863 hrpA 3991864 hrpA Escherichia coli UTI89 ATP-dependent RNA helicase HrpA YP_540644.2 1558018 D 364106 CDS YP_540645.1 91210659 3991865 1562136..1562936 1 NC_007946.1 hypothetical protein 1562936 ydcF 3991865 ydcF Escherichia coli UTI89 hypothetical protein YP_540645.1 1562136 D 364106 CDS YP_540646.1 91210660 3991866 1563133..1564572 1 NC_007946.1 NAD-linked; aldehyde dehydrogenase 1564572 aldA 3991866 aldA Escherichia coli UTI89 aldehyde dehydrogenase YP_540646.1 1563133 D 364106 CDS YP_540647.1 91210661 3991867 complement(1564614..1565615) 1 NC_007946.1 glyceraldehyde 3-phosphate dehydrogenase A 1565615 3991867 UTI89_C1638 Escherichia coli UTI89 glyceraldehyde 3-phosphate dehydrogenase A YP_540647.1 1564614 R 364106 CDS YP_540648.2 162138442 3991868 1565804..1566334 1 NC_007946.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1566334 cybB 3991868 cybB Escherichia coli UTI89 cytochrome b561 YP_540648.2 1565804 D 364106 CDS YP_540649.1 91210663 3991869 1566579..1566752 1 NC_007946.1 hypothetical protein 1566752 ydcA 3991869 ydcA Escherichia coli UTI89 hypothetical protein YP_540649.1 1566579 D 364106 CDS YP_540650.1 91210664 3991870 complement(1566825..1567316) 1 NC_007946.1 hypothetical protein 1567316 hok 3991870 hok Escherichia coli UTI89 hypothetical protein YP_540650.1 1566825 R 364106 CDS YP_540651.1 91210665 3991871 1566910..1567380 1 NC_007946.1 hypothetical protein 1567380 3991871 UTI89_C1642 Escherichia coli UTI89 hypothetical protein YP_540651.1 1566910 D 364106 CDS YP_540652.1 91210666 3991872 complement(1567418..1568482) 1 NC_007946.1 transcriptional regulator YdcI 1568482 ydcI 3991872 ydcI Escherichia coli UTI89 transcriptional regulator YdcI YP_540652.1 1567418 R 364106 CDS YP_540653.1 91210667 3991834 1568558..1569901 1 NC_007946.1 hypothetical protein 1569901 ydcJ 3991834 ydcJ Escherichia coli UTI89 hypothetical protein YP_540653.1 1568558 D 364106 CDS YP_540654.1 91210668 3991835 1570126..1571781 1 NC_007946.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1571781 mdoD 3991835 mdoD Escherichia coli UTI89 glucan biosynthesis protein D YP_540654.1 1570126 D 364106 CDS YP_540655.1 91210669 3991836 1571915..1572145 1 NC_007946.1 hypothetical protein 1572145 ydcH 3991836 ydcH Escherichia coli UTI89 hypothetical protein YP_540655.1 1571915 D 364106 CDS YP_540656.1 91210670 3991837 1572193..1572747 1 NC_007946.1 acetylation of N-terminal serine of 30S ribosomal subunit protein L7; ribosomal-protein-L7/L12-serine acetyltransferase 1572747 rimL 3991837 rimL Escherichia coli UTI89 ribosomal-protein-L7/L12-serine acetyltransferase YP_540656.1 1572193 D 364106 CDS YP_540657.1 91210671 3991838 complement(1572739..1573719) 1 NC_007946.1 hypothetical protein 1573719 ydcK 3991838 ydcK Escherichia coli UTI89 hypothetical protein YP_540657.1 1572739 R 364106 CDS YP_540658.1 91210672 3991839 1573735..1574835 1 NC_007946.1 potassium-tellurite ethidium and proflavin transporter 1574835 tehA 3991839 tehA Escherichia coli UTI89 potassium-tellurite ethidium and proflavin transporter YP_540658.1 1573735 D 364106 CDS YP_540659.1 91210673 3991840 1574832..1575425 1 NC_007946.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1575425 tehB 3991840 tehB Escherichia coli UTI89 tellurite resistance protein TehB YP_540659.1 1574832 D 364106 CDS YP_540660.1 91210674 3991841 1575728..1576396 1 NC_007946.1 hypothetical protein 1576396 3991841 UTI89_C1651 Escherichia coli UTI89 hypothetical protein YP_540660.1 1575728 D 364106 CDS YP_540661.1 91210675 3991842 complement(1576431..1577726) 1 NC_007946.1 hypothetical protein 1577726 ydcO 3991842 ydcO Escherichia coli UTI89 hypothetical protein YP_540661.1 1576431 R 364106 CDS YP_540662.1 91210676 3991843 1577695..1578231 1 NC_007946.1 hypothetical protein 1578231 ydcN 3991843 ydcN Escherichia coli UTI89 hypothetical protein YP_540662.1 1577695 D 364106 CDS YP_540663.1 91210677 3991844 1578262..1580265 1 NC_007946.1 protease YdcP 1580265 ydcP 3991844 ydcP Escherichia coli UTI89 protease YdcP YP_540663.1 1578262 D 364106 CDS YP_540664.1 91210678 3991845 complement(1580357..1580587) 1 NC_007946.1 hypothetical protein 1580587 yncJ 3991845 yncJ Escherichia coli UTI89 hypothetical protein YP_540664.1 1580357 R 364106 CDS YP_540665.1 91210679 3991846 complement(1580644..1580772) 1 NC_007946.1 hypothetical protein 1580772 3991846 UTI89_C1656 Escherichia coli UTI89 hypothetical protein YP_540665.1 1580644 R 364106 CDS YP_540666.1 91210680 3991847 1580799..1581002 1 NC_007946.1 hypothetical protein 1581002 3991847 UTI89_C1657 Escherichia coli UTI89 hypothetical protein YP_540666.1 1580799 D 364106 CDS YP_540667.1 91210681 3991848 1581081..1582487 1 NC_007946.1 hypothetical protein 1582487 ydcR 3991848 ydcR Escherichia coli UTI89 hypothetical protein YP_540667.1 1581081 D 364106 CDS YP_540668.1 91210682 3991849 1582732..1583877 1 NC_007946.1 ABC transporter periplasmic binding protein ydcS 1583877 ydcS 3991849 ydcS Escherichia coli UTI89 ABC transporter periplasmic binding protein ydcS YP_540668.1 1582732 D 364106 CDS YP_540669.1 91210683 3991850 1583895..1584908 1 NC_007946.1 ABC transporter ATP-binding protein 1584908 ydcT 3991850 ydcT Escherichia coli UTI89 ABC transporter ATP-binding protein YP_540669.1 1583895 D 364106 CDS YP_540670.1 91210684 3991851 1584909..1585850 1 NC_007946.1 ABC transporter permease 1585850 ydcU 3991851 ydcU Escherichia coli UTI89 ABC transporter permease YP_540670.1 1584909 D 364106 CDS YP_540671.1 91210685 3991852 1585840..1586634 1 NC_007946.1 transport system permease 1586634 3991852 UTI89_C1662 Escherichia coli UTI89 transport system permease YP_540671.1 1585840 D 364106 CDS YP_540672.1 91210686 3993521 1586656..1588080 1 NC_007946.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1588080 ydcW 3993521 ydcW Escherichia coli UTI89 gamma-aminobutyraldehyde dehydrogenase YP_540672.1 1586656 D 364106 CDS YP_540673.1 91210687 3993522 complement(1588269..1588547) 1 NC_007946.1 hypothetical protein 1588547 3993522 UTI89_C1664 Escherichia coli UTI89 hypothetical protein YP_540673.1 1588269 R 364106 CDS YP_540674.1 91210688 3993523 1588392..1588640 1 NC_007946.1 hypothetical protein 1588640 ydcX 3993523 ydcX Escherichia coli UTI89 hypothetical protein YP_540674.1 1588392 D 364106 CDS YP_540675.1 91210689 3993524 1588726..1588959 1 NC_007946.1 hypothetical protein 1588959 ydcY 3993524 ydcY Escherichia coli UTI89 hypothetical protein YP_540675.1 1588726 D 364106 CDS YP_540676.1 91210690 3993525 complement(1588960..1589409) 1 NC_007946.1 hypothetical protein 1589409 ydcZ 3993525 ydcZ Escherichia coli UTI89 hypothetical protein YP_540676.1 1588960 R 364106 CDS YP_540677.1 91210691 3993526 complement(1589406..1589987) 1 NC_007946.1 acetyltransferase YncA 1589987 yncA 3993526 yncA Escherichia coli UTI89 acetyltransferase YncA YP_540677.1 1589406 R 364106 CDS YP_540678.1 91210692 3993527 1590131..1590367 1 NC_007946.1 hypothetical protein 1590367 3993527 UTI89_C1669 Escherichia coli UTI89 hypothetical protein YP_540678.1 1590131 D 364106 CDS YP_540679.1 91210693 3993528 complement(1590405..1592507) 1 NC_007946.1 tonB-dependent receptor YncD 1592507 yncD 3993528 yncD Escherichia coli UTI89 tonB-dependent receptor YncD YP_540679.1 1590405 R 364106 CDS YP_540680.1 91210694 3993529 1592749..1593810 1 NC_007946.1 hypothetical protein 1593810 yncE 3993529 yncE Escherichia coli UTI89 hypothetical protein YP_540680.1 1592749 D 364106 CDS YP_540681.1 91210695 3993530 complement(1593923..1595473) 1 NC_007946.1 L-asparagine permease 1595473 ansP 3993530 ansP Escherichia coli UTI89 L-asparagine permease YP_540681.1 1593923 R 364106 CDS YP_540682.1 91210696 3993531 1595689..1595865 1 NC_007946.1 transferase 1595865 3993531 UTI89_C1673 Escherichia coli UTI89 transferase YP_540682.1 1595689 D 364106 CDS YP_540683.1 91210697 3993532 1595978..1596289 1 NC_007946.1 hypothetical protein 1596289 3993532 UTI89_C1674 Escherichia coli UTI89 hypothetical protein YP_540683.1 1595978 D 364106 CDS YP_540684.1 91210698 3993533 1596830..1597114 1 NC_007946.1 hypothetical protein 1597114 3993533 UTI89_C1675 Escherichia coli UTI89 hypothetical protein YP_540684.1 1596830 D 364106 CDS YP_540685.1 91210699 3993534 1597133..1599538 1 NC_007946.1 hypothetical protein 1599538 3993534 UTI89_C1676 Escherichia coli UTI89 hypothetical protein YP_540685.1 1597133 D 364106 CDS YP_540686.1 91210700 3993535 1599492..1600289 1 NC_007946.1 hypothetical protein 1600289 3993535 UTI89_C1677 Escherichia coli UTI89 hypothetical protein YP_540686.1 1599492 D 364106 CDS YP_540687.1 91210701 3993536 1600660..1601127 1 NC_007946.1 hypothetical protein 1601127 3993536 UTI89_C1678 Escherichia coli UTI89 hypothetical protein YP_540687.1 1600660 D 364106 CDS YP_540688.1 91210702 3993537 1601240..1601383 1 NC_007946.1 hypothetical protein 1601383 3993537 UTI89_C1679 Escherichia coli UTI89 hypothetical protein YP_540688.1 1601240 D 364106 CDS YP_540689.1 91210703 3993538 complement(1601993..1602562) 1 NC_007946.1 hypothetical protein 1602562 yddH 3993538 yddH Escherichia coli UTI89 hypothetical protein YP_540689.1 1601993 R 364106 CDS YP_540690.1 91210704 3993539 1602737..1603582 1 NC_007946.1 N-hydroxyarylamine O-acetyltransferase 1603582 nhoA 3993539 nhoA Escherichia coli UTI89 N-hydroxyarylamine O-acetyltransferase YP_540690.1 1602737 D 364106 CDS YP_540691.1 91210705 3993540 complement(1603678..1604571) 1 NC_007946.1 hypothetical protein 1604571 yddE 3993540 yddE Escherichia coli UTI89 hypothetical protein YP_540691.1 1603678 R 364106 CDS YP_540692.1 91210706 3991165 complement(1604651..1605331) 1 NC_007946.1 respiratory nitrate reductase 2 subunit gamma 1605331 narV 3991165 narV Escherichia coli UTI89 respiratory nitrate reductase 2 subunit gamma YP_540692.1 1604651 R 364106 CDS YP_540693.1 91210707 3991166 complement(1605328..1606023) 1 NC_007946.1 cryptic nitrate reductase 2 subunit delta 1606023 narW 3991166 narW Escherichia coli UTI89 cryptic nitrate reductase 2 subunit delta YP_540693.1 1605328 R 364106 CDS YP_540694.1 91210708 3991167 complement(1606023..1607567) 1 NC_007946.1 cryptic nitrate reductase 2 subunit beta 1607567 narY 3991167 narY Escherichia coli UTI89 cryptic nitrate reductase 2 subunit beta YP_540694.1 1606023 R 364106 CDS YP_540695.1 91210709 3991168 complement(1607564..1611427) 1 NC_007946.1 respiratory nitrate reductase 2 subunit alpha 1611427 narZ 3991168 narZ Escherichia coli UTI89 respiratory nitrate reductase 2 subunit alpha YP_540695.1 1607564 R 364106 CDS YP_540696.1 91210710 3991169 complement(1611399..1612787) 1 NC_007946.1 nitrite extrusion protein 2 1612787 narU 3991169 narU Escherichia coli UTI89 nitrite extrusion protein 2 YP_540696.1 1611399 R 364106 CDS YP_540697.1 91210711 3991170 complement(1613060..1613941) 1 NC_007946.1 hypothetical protein 1613941 yddG 3991170 yddG Escherichia coli UTI89 hypothetical protein YP_540697.1 1613060 R 364106 CDS YP_540698.1 91210712 3991171 1614173..1617220 1 NC_007946.1 FdnG subunit alpha of formate dehydrogenase-N 1617220 fdnG 3991171 fdnG Escherichia coli UTI89 FdnG subunit alpha of formate dehydrogenase-N YP_540698.1 1614173 D 364106 CDS YP_540699.1 91210713 3991172 complement(1617197..1618138) 1 NC_007946.1 hypothetical protein 1618138 3991172 UTI89_C1690 Escherichia coli UTI89 hypothetical protein YP_540699.1 1617197 R 364106 CDS YP_540700.1 91210714 3991173 1617233..1618117 1 NC_007946.1 formate dehydrogenase-N subunit beta 1618117 fdnH 3991173 fdnH Escherichia coli UTI89 formate dehydrogenase-N subunit beta YP_540700.1 1617233 D 364106 CDS YP_540701.1 91210715 3991174 1618110..1618763 1 NC_007946.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1618763 fdnI 3991174 fdnI Escherichia coli UTI89 formate dehydrogenase-N subunit gamma YP_540701.1 1618110 D 364106 CDS YP_540702.1 91210716 3991175 1618966..1619238 1 NC_007946.1 hypothetical protein 1619238 3991175 UTI89_C1693 Escherichia coli UTI89 hypothetical protein YP_540702.1 1618966 D 364106 CDS YP_540703.1 91210717 3991176 complement(1618992..1619276) 1 NC_007946.1 hypothetical protein 1619276 3991176 UTI89_C1694 Escherichia coli UTI89 hypothetical protein YP_540703.1 1618992 R 364106 CDS YP_540704.1 91210718 3991177 complement(1619276..1619548) 1 NC_007946.1 hypothetical protein 1619548 3991177 UTI89_C1695 Escherichia coli UTI89 hypothetical protein YP_540704.1 1619276 R 364106 CDS YP_540705.1 91210719 3991178 complement(1619740..1620780) 1 NC_007946.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1620780 adhP 3991178 adhP Escherichia coli UTI89 alcohol dehydrogenase YP_540705.1 1619740 R 364106 CDS YP_540706.1 91210720 3991179 complement(1620884..1622608) 1 NC_007946.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1622608 sfcA 3991179 sfcA Escherichia coli UTI89 malate dehydrogenase YP_540706.1 1620884 R 364106 CDS YP_540707.1 91210721 3991180 complement(1622737..1622874) 1 NC_007946.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1622874 rpsV 3991180 rpsV Escherichia coli UTI89 30S ribosomal subunit S22 YP_540707.1 1622737 R 364106 CDS YP_540708.2 162138441 3991181 complement(1622976..1623191) 1 NC_007946.1 biofilm-dependent modulation protein 1623191 bdm 3991181 bdm Escherichia coli UTI89 biofilm-dependent modulation protein YP_540708.2 1622976 R 364106 CDS YP_540709.1 91210723 3991182 1623358..1623498 1 NC_007946.1 hypothetical protein 1623498 3991182 UTI89_C1700 Escherichia coli UTI89 hypothetical protein YP_540709.1 1623358 D 364106 CDS YP_540710.1 91210724 3991183 1623536..1623967 1 NC_007946.1 osmotically inducible protein OsmC 1623967 osmC 3991183 osmC Escherichia coli UTI89 osmotically inducible protein OsmC YP_540710.1 1623536 D 364106 CDS YP_540711.1 91210725 3991441 complement(1624157..1626580) 1 NC_007946.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1626580 3991441 UTI89_C1702 Escherichia coli UTI89 cAMP phosphodiesterase YP_540711.1 1624157 R 364106 CDS YP_540712.1 91210726 3991442 complement(1626581..1626799) 1 NC_007946.1 hypothetical protein 1626799 3991442 UTI89_C1703 Escherichia coli UTI89 hypothetical protein YP_540712.1 1626581 R 364106 CDS YP_540713.1 91210727 3991443 complement(1626652..1626825) 1 NC_007946.1 hypothetical protein 1626825 3991443 UTI89_C1704 Escherichia coli UTI89 hypothetical protein YP_540713.1 1626652 R 364106 CDS YP_540714.1 91210728 3991444 complement(1627123..1628442) 1 NC_007946.1 lipoprotein YddW 1628442 yddW 3991444 yddW Escherichia coli UTI89 lipoprotein YddW YP_540714.1 1627123 R 364106 CDS YP_540715.1 91210729 3991445 complement(1628573..1630108) 1 NC_007946.1 amino acid antiporter 1630108 xasA 3991445 xasA Escherichia coli UTI89 amino acid antiporter YP_540715.1 1628573 R 364106 CDS YP_540716.1 91210730 3991446 complement(1630264..1631733) 1 NC_007946.1 glutamate decarboxylase beta 1631733 gadB 3991446 gadB Escherichia coli UTI89 glutamate decarboxylase beta YP_540716.1 1630264 R 364106 CDS YP_540717.1 91210731 3991447 complement(1632025..1634820) 1 NC_007946.1 zinc protease PqqL 1634820 pqqL 3991447 pqqL Escherichia coli UTI89 zinc protease PqqL YP_540717.1 1632025 R 364106 CDS YP_540718.1 91210732 3991448 complement(1634865..1637237) 1 NC_007946.1 hypothetical protein 1637237 yddB 3991448 yddB Escherichia coli UTI89 hypothetical protein YP_540718.1 1634865 R 364106 CDS YP_540719.1 91210733 3991449 complement(1637275..1638960) 1 NC_007946.1 ABC transporter ATP-binding protein 1638960 yddA 3991449 yddA Escherichia coli UTI89 ABC transporter ATP-binding protein YP_540719.1 1637275 R 364106 CDS YP_540720.1 91210734 3991450 complement(1639251..1640423) 1 NC_007946.1 hypothetical protein 1640423 ydeM 3991450 ydeM Escherichia coli UTI89 hypothetical protein YP_540720.1 1639251 R 364106 CDS YP_540721.1 91210735 3991451 complement(1640460..1642175) 1 NC_007946.1 sulfatase YdeN 1642175 ydeN 3991451 ydeN Escherichia coli UTI89 sulfatase YdeN YP_540721.1 1640460 R 364106 CDS YP_540722.1 91210736 3991452 complement(1642544..1643305) 1 NC_007946.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1643305 3991452 UTI89_C1713 Escherichia coli UTI89 transcriptional regulator YdeO YP_540722.1 1642544 R 364106 CDS YP_540723.1 91210737 3991453 complement(1643380..1643577) 1 NC_007946.1 hypothetical protein 1643577 3991453 UTI89_C1714 Escherichia coli UTI89 hypothetical protein YP_540723.1 1643380 R 364106 CDS YP_540724.1 91210738 3991454 complement(1643825..1646104) 1 NC_007946.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase 1646104 ydeP 3991454 ydeP Escherichia coli UTI89 oxidoreductase YP_540724.1 1643825 R 364106 CDS YP_540725.1 91210739 3991455 complement(1646443..1647357) 1 NC_007946.1 synonym: ydeQ; Fml fimbrial adhesin FmlD 1647357 fmlD 3991455 fmlD Escherichia coli UTI89 Fml fimbrial adhesin FmlD YP_540725.1 1646443 R 364106 CDS YP_540726.1 91210740 3991456 complement(1647682..1649232) 1 NC_007946.1 outer membrane usher FmlC protein 1649232 fmlC 3991456 fmlC Escherichia coli UTI89 outer membrane usher FmlC protein YP_540726.1 1647682 R 364106 CDS YP_540727.1 91210741 3991457 complement(1649274..1649984) 1 NC_007946.1 periplasmic chaperone FmlB protein 1649984 fmlB 3991457 fmlB Escherichia coli UTI89 periplasmic chaperone FmlB protein YP_540727.1 1649274 R 364106 CDS YP_540728.1 91210742 3991458 complement(1650346..1650957) 1 NC_007946.1 Fml fimbriae subunit 1650957 fmlA 3991458 fmlA Escherichia coli UTI89 Fml fimbriae subunit YP_540728.1 1650346 R 364106 CDS YP_540729.1 91210743 3991459 complement(1651437..1651679) 1 NC_007946.1 hypothetical protein 1651679 3991459 UTI89_C1720 Escherichia coli UTI89 hypothetical protein YP_540729.1 1651437 R 364106 CDS YP_540730.1 91210744 3991460 complement(1651685..1652467) 1 NC_007946.1 hypothetical protein 1652467 3991460 UTI89_C1721 Escherichia coli UTI89 hypothetical protein YP_540730.1 1651685 R 364106 CDS YP_540731.1 91210745 3991571 1652577..1652834 1 NC_007946.1 hypothetical protein 1652834 3991571 UTI89_C1722 Escherichia coli UTI89 hypothetical protein YP_540731.1 1652577 D 364106 CDS YP_540732.1 91210746 3991572 complement(1653155..1653403) 1 NC_007946.1 hypothetical protein 1653403 3991572 UTI89_C1723 Escherichia coli UTI89 hypothetical protein YP_540732.1 1653155 R 364106 CDS YP_540733.1 91210747 3991573 1653363..1653728 1 NC_007946.1 hypothetical protein 1653728 3991573 UTI89_C1724 Escherichia coli UTI89 hypothetical protein YP_540733.1 1653363 D 364106 CDS YP_540734.1 91210748 3991574 complement(1653886..1655130) 1 NC_007946.1 phage-related secreted protein 1655130 3991574 UTI89_C1725 Escherichia coli UTI89 phage-related secreted protein YP_540734.1 1653886 R 364106 CDS YP_540735.1 91210749 3991575 complement(1655130..1656155) 1 NC_007946.1 phage-related membrane protein 1656155 3991575 UTI89_C1726 Escherichia coli UTI89 phage-related membrane protein YP_540735.1 1655130 R 364106 CDS YP_540736.1 91210750 3991576 1656130..1656462 1 NC_007946.1 hypothetical protein 1656462 3991576 UTI89_C1727 Escherichia coli UTI89 hypothetical protein YP_540736.1 1656130 D 364106 CDS YP_540737.1 91210751 3991577 complement(1656159..1656446) 1 NC_007946.1 phage-related membrane protein 1656446 3991577 UTI89_C1728 Escherichia coli UTI89 phage-related membrane protein YP_540737.1 1656159 R 364106 CDS YP_540738.1 91210752 3991578 complement(1656459..1658171) 1 NC_007946.1 hypothetical protein 1658171 3991578 UTI89_C1729 Escherichia coli UTI89 hypothetical protein YP_540738.1 1656459 R 364106 CDS YP_540739.1 91210753 3991579 complement(1658236..1658469) 1 NC_007946.1 phage-related membrane protein 1658469 3991579 UTI89_C1730 Escherichia coli UTI89 phage-related membrane protein YP_540739.1 1658236 R 364106 CDS YP_540740.1 91210754 3991580 complement(1658504..1658755) 1 NC_007946.1 phage-related membrane protein 1658755 3991580 UTI89_C1731 Escherichia coli UTI89 phage-related membrane protein YP_540740.1 1658504 R 364106 CDS YP_540741.1 91210755 3991581 complement(1658758..1659075) 1 NC_007946.1 hypothetical protein 1659075 3991581 UTI89_C1732 Escherichia coli UTI89 hypothetical protein YP_540741.1 1658758 R 364106 CDS YP_540742.1 91210756 3991582 complement(1659087..1660139) 1 NC_007946.1 hypothetical protein 1660139 3991582 UTI89_C1733 Escherichia coli UTI89 hypothetical protein YP_540742.1 1659087 R 364106 CDS YP_540743.1 91210757 3991583 1660335..1660757 1 NC_007946.1 hypothetical protein 1660757 3991583 UTI89_C1734 Escherichia coli UTI89 hypothetical protein YP_540743.1 1660335 D 364106 CDS YP_540744.1 91210758 3991584 1660857..1661279 1 NC_007946.1 hypothetical protein 1661279 3991584 UTI89_C1735 Escherichia coli UTI89 hypothetical protein YP_540744.1 1660857 D 364106 CDS YP_540745.1 91210759 3991585 1661387..1662496 1 NC_007946.1 hypothetical protein 1662496 3991585 UTI89_C1736 Escherichia coli UTI89 hypothetical protein YP_540745.1 1661387 D 364106 CDS YP_540746.1 91210760 3991586 complement(1664002..1664286) 1 NC_007946.1 DNA-binding transcriptional regulator HipB 1664286 hipB 3991586 hipB Escherichia coli UTI89 DNA-binding transcriptional regulator HipB YP_540746.1 1664002 R 364106 CDS YP_540747.1 91210761 3991587 1664576..1665334 1 NC_007946.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1665334 tam 3991587 tam Escherichia coli UTI89 trans-aconitate 2-methyltransferase YP_540747.1 1664576 D 364106 CDS YP_540748.1 91210762 3991588 complement(1665338..1666303) 1 NC_007946.1 hypothetical protein 1666303 yneE 3991588 yneE Escherichia coli UTI89 hypothetical protein YP_540748.1 1665338 R 364106 CDS YP_540749.1 91210763 3991589 complement(1666449..1667900) 1 NC_007946.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1667900 uxaB 3991589 uxaB Escherichia coli UTI89 altronate oxidoreductase YP_540749.1 1666449 R 364106 CDS YP_540750.1 91210764 3991718 complement(1668127..1669545) 1 NC_007946.1 hypothetical protein 1669545 yneF 3991718 yneF Escherichia coli UTI89 hypothetical protein YP_540750.1 1668127 R 364106 CDS YP_540751.1 91210765 3991719 complement(1669684..1670043) 1 NC_007946.1 hypothetical protein 1670043 yneG 3991719 yneG Escherichia coli UTI89 hypothetical protein YP_540751.1 1669684 R 364106 CDS YP_540752.1 91210766 3991720 complement(1670043..1670969) 1 NC_007946.1 catalyzes the formation of glutamate from glutamine; glutaminase 1670969 yneH 3991720 yneH Escherichia coli UTI89 glutaminase YP_540752.1 1670043 R 364106 CDS YP_540753.1 91210767 3991721 complement(1671033..1672445) 1 NC_007946.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1672445 yneI 3991721 yneI Escherichia coli UTI89 succinate semialdehyde dehydrogenase YP_540753.1 1671033 R 364106 CDS YP_540754.1 91210768 3991722 1672522..1673403 1 NC_007946.1 transcriptional regulator YneJ 1673403 yneJ 3991722 yneJ Escherichia coli UTI89 transcriptional regulator YneJ YP_540754.1 1672522 D 364106 CDS YP_540755.1 91210769 3991723 1673481..1673600 1 NC_007946.1 hypothetical protein 1673600 yneK 3991723 yneK Escherichia coli UTI89 hypothetical protein YP_540755.1 1673481 D 364106 CDS YP_540756.1 91210770 3991724 1673742..1674932 1 NC_007946.1 sugar efflux transporter 1674932 sotB 3991724 sotB Escherichia coli UTI89 sugar efflux transporter YP_540756.1 1673742 D 364106 CDS YP_540757.1 91210771 3991725 complement(1674957..1675622) 1 NC_007946.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1675622 marC 3991725 marC Escherichia coli UTI89 multiple drug resistance protein MarC YP_540757.1 1674957 R 364106 CDS YP_540758.1 91210772 3991726 1675834..1676268 1 NC_007946.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1676268 marR 3991726 marR Escherichia coli UTI89 DNA-binding transcriptional repressor MarR YP_540758.1 1675834 D 364106 CDS YP_540759.2 162138440 3991727 1676289..1676672 1 NC_007946.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1676672 marA 3991727 marA Escherichia coli UTI89 DNA-binding transcriptional activator MarA YP_540759.2 1676289 D 364106 CDS YP_540760.1 91210774 3991728 1676704..1676922 1 NC_007946.1 hypothetical protein 1676922 marB 3991728 marB Escherichia coli UTI89 hypothetical protein YP_540760.1 1676704 D 364106 CDS YP_540761.1 91210775 3991729 complement(1676979..1678424) 1 NC_007946.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 1678424 celA 3991729 celA Escherichia coli UTI89 6-phospho-beta-glucosidase YP_540761.1 1676979 R 364106 CDS YP_540762.1 91210776 3991730 complement(1678442..1680115) 1 NC_007946.1 outer membrane protein YieC 1680115 3991730 UTI89_C1753 Escherichia coli UTI89 outer membrane protein YieC YP_540762.1 1678442 R 364106 CDS YP_540763.1 91210777 3991731 complement(1680170..1680484) 1 NC_007946.1 PTS system cellobiose-specific transporter subunit IIA 1680484 3991731 UTI89_C1754 Escherichia coli UTI89 PTS system cellobiose-specific transporter subunit IIA YP_540763.1 1680170 R 364106 CDS YP_540764.1 91210778 3991732 complement(1680509..1681870) 1 NC_007946.1 hypothetical protein 1681870 3991732 UTI89_C1755 Escherichia coli UTI89 hypothetical protein YP_540764.1 1680509 R 364106 CDS YP_540765.1 91210779 3991733 complement(1681946..1682257) 1 NC_007946.1 PTS system cellobiose-specific transporter subunit IIB 1682257 3991733 UTI89_C1756 Escherichia coli UTI89 PTS system cellobiose-specific transporter subunit IIB YP_540765.1 1681946 R 364106 CDS YP_540766.1 91210780 3991734 1682456..1683154 1 NC_007946.1 hypothetical protein 1683154 3991734 UTI89_C1757 Escherichia coli UTI89 hypothetical protein YP_540766.1 1682456 D 364106 CDS YP_540767.2 162138439 3991735 complement(1683199..1684098) 1 NC_007946.1 O-acetylserine/cysteine export protein 1684098 ydeD 3991735 ydeD Escherichia coli UTI89 O-acetylserine/cysteine export protein YP_540767.2 1683199 R 364106 CDS YP_540768.1 91210782 3991736 1684293..1685480 1 NC_007946.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1685480 ydeF 3991736 ydeF Escherichia coli UTI89 MFS-type transporter YdeE YP_540768.1 1684293 D 364106 CDS YP_540769.1 91210783 3991737 complement(1685921..1686817) 1 NC_007946.1 hypothetical protein 1686817 ydeH 3991737 ydeH Escherichia coli UTI89 hypothetical protein YP_540769.1 1685921 R 364106 CDS YP_540770.1 91210784 3990612 complement(1687319..1689430) 1 NC_007946.1 dipeptidyl carboxypeptidase II 1689430 dcp 3990612 dcp Escherichia coli UTI89 dipeptidyl carboxypeptidase II YP_540770.1 1687319 R 364106 CDS YP_540771.1 91210785 3990613 1689486..1690247 1 NC_007946.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1690247 ydfG 3990613 ydfG Escherichia coli UTI89 3-hydroxy acid dehydrogenase YP_540771.1 1689486 D 364106 CDS YP_540772.1 91210786 3990614 1690336..1691022 1 NC_007946.1 hypothetical protein 1691022 ydfH 3990614 ydfH Escherichia coli UTI89 hypothetical protein YP_540772.1 1690336 D 364106 CDS YP_540773.1 91210787 3990615 complement(1691157..1691429) 1 NC_007946.1 hypothetical protein 1691429 3990615 UTI89_C1764 Escherichia coli UTI89 hypothetical protein YP_540773.1 1691157 R 364106 CDS YP_540774.1 91210788 3990616 1691199..1691402 1 NC_007946.1 hypothetical protein 1691402 ydfZ 3990616 ydfZ Escherichia coli UTI89 hypothetical protein YP_540774.1 1691199 D 364106 CDS YP_540775.1 91210789 3990617 complement(1691438..1692898) 1 NC_007946.1 oxidoreductase YdfI 1692898 ydfI 3990617 ydfI Escherichia coli UTI89 oxidoreductase YdfI YP_540775.1 1691438 R 364106 CDS YP_540776.1 91210790 3990618 complement(1693399..1694442) 1 NC_007946.1 dehydrogenase 1694442 rspB 3990618 rspB Escherichia coli UTI89 dehydrogenase YP_540776.1 1693399 R 364106 CDS YP_540777.1 91210791 3990619 complement(1694430..1695677) 1 NC_007946.1 starvation sensing protein RspA 1695677 rspA 3990619 rspA Escherichia coli UTI89 starvation sensing protein RspA YP_540777.1 1694430 R 364106 CDS YP_540778.1 91210792 3990620 complement(1695850..1696185) 1 NC_007946.1 hypothetical protein 1696185 ynfA 3990620 ynfA Escherichia coli UTI89 hypothetical protein YP_540778.1 1695850 R 364106 CDS YP_540779.1 91210793 3990621 1696311..1696652 1 NC_007946.1 hypothetical protein 1696652 ynfB 3990621 ynfB Escherichia coli UTI89 hypothetical protein YP_540779.1 1696311 D 364106 CDS YP_540780.1 91210794 3990622 1696687..1697247 1 NC_007946.1 spermidine N(1)-acetyltransferase 1697247 speG 3990622 speG Escherichia coli UTI89 spermidine N(1)-acetyltransferase YP_540780.1 1696687 D 364106 CDS YP_540781.1 91210795 3990623 complement(1697250..1697996) 1 NC_007946.1 hypothetical protein 1697996 ynfC 3990623 ynfC Escherichia coli UTI89 hypothetical protein YP_540781.1 1697250 R 364106 CDS YP_540782.1 91210796 3990624 1698026..1698373 1 NC_007946.1 hypothetical protein 1698373 ynfD 3990624 ynfD Escherichia coli UTI89 hypothetical protein YP_540782.1 1698026 D 364106 CDS YP_540783.1 91210797 3990625 1698572..1700998 1 NC_007946.1 dimethyl sulfoxide reductase chain YnfE 1700998 ynfE 3990625 ynfE Escherichia coli UTI89 dimethyl sulfoxide reductase chain YnfE YP_540783.1 1698572 D 364106 CDS YP_540784.1 91210798 3990626 1701056..1703482 1 NC_007946.1 dimethyl sulfoxide reductase chain YnfF 1703482 ynfF 3990626 ynfF Escherichia coli UTI89 dimethyl sulfoxide reductase chain YnfF YP_540784.1 1701056 D 364106 CDS YP_540785.1 91210799 3990627 1703493..1704110 1 NC_007946.1 DmsB-like; dimethyl sulfoxide reductase-like subunit; Fe-S subunit oxidoreductase 1704110 ynfG 3990627 ynfG Escherichia coli UTI89 Fe-S subunit oxidoreductase YP_540785.1 1703493 D 364106 CDS YP_540786.1 91210800 3990628 1704112..1704966 1 NC_007946.1 anaerobic dimethyl sulfoxide reductase chain YnfH 1704966 ynfH 3990628 ynfH Escherichia coli UTI89 anaerobic dimethyl sulfoxide reductase chain YnfH YP_540786.1 1704112 D 364106 CDS YP_540787.2 162138438 3990629 1705009..1705623 1 NC_007946.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1705623 ynfI 3990629 ynfI Escherichia coli UTI89 twin-argninine leader-binding protein DmsD YP_540787.2 1705009 D 364106 CDS YP_540788.2 162138437 3990630 1705820..1707001 1 NC_007946.1 voltage-gated ClC-type chloride channel ClcB 1707001 ynfJ 3990630 ynfJ Escherichia coli UTI89 voltage-gated ClC-type chloride channel ClcB YP_540788.2 1705820 D 364106 CDS YP_540789.1 91210803 3993946 complement(1706954..1707661) 1 NC_007946.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1707661 ynfK 3993946 ynfK Escherichia coli UTI89 dithiobiotin synthetase YP_540789.1 1706954 R 364106 CDS YP_540790.1 91210804 3993947 complement(1707774..1708994) 1 NC_007946.1 NAGC-like transcriptional regulator 1708994 mlc 3993947 mlc Escherichia coli UTI89 NAGC-like transcriptional regulator YP_540790.1 1707774 R 364106 CDS YP_540791.1 91210805 3993948 complement(1709129..1710022) 1 NC_007946.1 transcriptional regulator YnfL 1710022 ynfL 3993948 ynfL Escherichia coli UTI89 transcriptional regulator YnfL YP_540791.1 1709129 R 364106 CDS YP_540792.1 91210806 3993949 1710129..1711382 1 NC_007946.1 transport protein YnfM 1711382 ynfM 3993949 ynfM Escherichia coli UTI89 transport protein YnfM YP_540792.1 1710129 D 364106 CDS YP_540793.1 91210807 3993950 1711780..1712115 1 NC_007946.1 required for growth and survival under moderately acid conditions; acid shock protein 1712115 3993950 UTI89_C1784 Escherichia coli UTI89 acid shock protein YP_540793.1 1711780 D 364106 CDS YP_540795.1 91210809 3993952 1712391..1713212 1 NC_007946.1 hypothetical protein 1713212 3993952 UTI89_C1786 Escherichia coli UTI89 hypothetical protein YP_540795.1 1712391 D 364106 CDS YP_540796.1 91210810 3993953 complement(1713251..1713580) 1 NC_007946.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1713580 ydgE 3993953 ydgE Escherichia coli UTI89 multidrug efflux system protein MdtI YP_540796.1 1713251 R 364106 CDS YP_540797.1 91210811 3993954 complement(1713567..1713932) 1 NC_007946.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1713932 ydgF 3993954 ydgF Escherichia coli UTI89 multidrug efflux system protein MdtJ YP_540797.1 1713567 R 364106 CDS YP_540798.1 91210812 3993955 1714343..1715377 1 NC_007946.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 1715377 tqsA 3993955 tqsA Escherichia coli UTI89 transport protein YP_540798.1 1714343 D 364106 CDS YP_540799.1 91210813 3993956 complement(1715402..1716790) 1 NC_007946.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1716790 pntB 3993956 pntB Escherichia coli UTI89 pyridine nucleotide transhydrogenase YP_540799.1 1715402 R 364106 CDS YP_540800.1 91210814 3993957 complement(1716801..1718387) 1 NC_007946.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1718387 pntA 3993957 pntA Escherichia coli UTI89 NAD(P) transhydrogenase subunit alpha YP_540800.1 1716801 R 364106 CDS YP_540801.1 91210815 3993958 1718857..1719801 1 NC_007946.1 hypothetical protein 1719801 3993958 UTI89_C1792 Escherichia coli UTI89 hypothetical protein YP_540801.1 1718857 D 364106 CDS YP_540802.1 91210816 3993959 1719987..1721369 1 NC_007946.1 arginine/ornithine antiporter 1721369 ydgI 3993959 ydgI Escherichia coli UTI89 arginine/ornithine antiporter YP_540802.1 1719987 D 364106 CDS YP_540803.1 91210817 3993960 1721406..1722128 1 NC_007946.1 short chain dehydrogenase 1722128 ydgB 3993960 ydgB Escherichia coli UTI89 short chain dehydrogenase YP_540803.1 1721406 D 364106 CDS YP_540804.1 91210818 3993961 complement(1722125..1722460) 1 NC_007946.1 hypothetical protein 1722460 ydgC 3993961 ydgC Escherichia coli UTI89 hypothetical protein YP_540804.1 1722125 R 364106 CDS YP_540805.1 91210819 3993962 1722529..1723308 1 NC_007946.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1723308 rstA 3993962 rstA Escherichia coli UTI89 DNA-binding transcriptional regulator RstA YP_540805.1 1722529 D 364106 CDS YP_540806.1 91210820 3993963 1723312..1724613 1 NC_007946.1 sensor protein RstB 1724613 rstB 3993963 rstB Escherichia coli UTI89 sensor protein RstB YP_540806.1 1723312 D 364106 CDS YP_540807.1 91210821 3993964 1724677..1725618 1 NC_007946.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1725618 tus 3993964 tus Escherichia coli UTI89 DNA replication terminus site-binding protein YP_540807.1 1724677 D 364106 CDS YP_540808.1 91210822 3993965 complement(1725615..1727018) 1 NC_007946.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1727018 fumC 3993965 fumC Escherichia coli UTI89 fumarate hydratase YP_540808.1 1725615 R 364106 CDS YP_540809.1 91210823 3992854 complement(1727161..1728807) 1 NC_007946.1 fumarase A 1728807 fumA 3992854 fumA Escherichia coli UTI89 fumarase A YP_540809.1 1727161 R 364106 CDS YP_540810.1 91210824 3992855 1729006..1730181 1 NC_007946.1 mannose-6-phosphate isomerase 1730181 manA 3992855 manA Escherichia coli UTI89 mannose-6-phosphate isomerase YP_540810.1 1729006 D 364106 CDS YP_540811.1 91210825 3992856 1730282..1731790 1 NC_007946.1 hypothetical protein 1731790 ydgA 3992856 ydgA Escherichia coli UTI89 hypothetical protein YP_540811.1 1730282 D 364106 CDS YP_540812.1 91210826 3992857 complement(1731835..1733100) 1 NC_007946.1 porin 1733100 uidC 3992857 uidC Escherichia coli UTI89 porin YP_540812.1 1731835 R 364106 CDS YP_540813.1 91210827 3992858 complement(1733139..1734512) 1 NC_007946.1 glucuronide transporter 1734512 uidB 3992858 uidB Escherichia coli UTI89 glucuronide transporter YP_540813.1 1733139 R 364106 CDS YP_540814.1 91210828 3992859 complement(1734509..1736320) 1 NC_007946.1 beta-D-glucuronidase 1736320 uidA 3992859 uidA Escherichia coli UTI89 beta-D-glucuronidase YP_540814.1 1734509 R 364106 CDS YP_540815.1 91210829 3992860 complement(1736710..1737300) 1 NC_007946.1 repressor for uid operon 1737300 uidR 3992860 uidR Escherichia coli UTI89 repressor for uid operon YP_540815.1 1736710 R 364106 CDS YP_540816.1 91210830 3992861 complement(1737529..1738296) 1 NC_007946.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1738296 hdhA 3992861 hdhA Escherichia coli UTI89 7-alpha-hydroxysteroid dehydrogenase YP_540816.1 1737529 R 364106 CDS YP_540817.1 91210831 3992862 complement(1738408..1739436) 1 NC_007946.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1739436 malI 3992862 malI Escherichia coli UTI89 DNA-binding transcriptional repressor MalI YP_540817.1 1738408 R 364106 CDS YP_540818.1 91210832 3992863 1739407..1741203 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1741203 malX 3992863 malX Escherichia coli UTI89 bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_540818.1 1739407 D 364106 CDS YP_540819.1 91210833 3992864 1741213..1742385 1 NC_007946.1 maltose regulon modulator 1742385 malY 3992864 malY Escherichia coli UTI89 maltose regulon modulator YP_540819.1 1741213 D 364106 CDS YP_540820.1 91210834 3992865 1742489..1743490 1 NC_007946.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1743490 add 3992865 add Escherichia coli UTI89 adenosine deaminase YP_540820.1 1742489 D 364106 CDS YP_540821.2 162138436 3992866 complement(1743526..1744566) 1 NC_007946.1 oxidoreductase 1744566 ydgJ 3992866 ydgJ Escherichia coli UTI89 oxidoreductase YP_540821.2 1743526 R 364106 CDS YP_540822.1 91210836 3992867 1744809..1744934 1 NC_007946.1 beta-lactam resistance protein 1744934 3992867 UTI89_C1813 Escherichia coli UTI89 beta-lactam resistance protein YP_540822.1 1744809 D 364106 CDS YP_540823.1 91210837 3992868 1745023..1745286 1 NC_007946.1 hypothetical protein 1745286 3992868 UTI89_C1814 Escherichia coli UTI89 hypothetical protein YP_540823.1 1745023 D 364106 CDS YP_540824.1 91210838 3992869 1745207..1745422 1 NC_007946.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1745422 ydgT 3992869 ydgT Escherichia coli UTI89 oriC-binding nucleoid-associated protein YP_540824.1 1745207 D 364106 CDS YP_540825.1 91210839 3992870 1745484..1745948 1 NC_007946.1 hypothetical protein 1745948 ydgK 3992870 ydgK Escherichia coli UTI89 hypothetical protein YP_540825.1 1745484 D 364106 CDS YP_540826.1 91210840 3992871 1746025..1746606 1 NC_007946.1 Na(+)-translocating NADH-quinone reductase subunit E 1746606 rnfA 3992871 rnfA Escherichia coli UTI89 Na(+)-translocating NADH-quinone reductase subunit E YP_540826.1 1746025 D 364106 CDS YP_540827.1 91210841 3992872 1746606..1747184 1 NC_007946.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1747184 rnfB 3992872 rnfB Escherichia coli UTI89 electron transport complex protein RnfB YP_540827.1 1746606 D 364106 CDS YP_540828.1 91210842 3992756 1747177..1749303 1 NC_007946.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1749303 rnfC 3992756 rnfC Escherichia coli UTI89 electron transport complex protein RnfC YP_540828.1 1747177 D 364106 CDS YP_540829.1 91210843 3992757 1749304..1750362 1 NC_007946.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1750362 rnfD 3992757 rnfD Escherichia coli UTI89 electron transport complex protein RnfD YP_540829.1 1749304 D 364106 CDS YP_540830.1 91210844 3992758 1750366..1750986 1 NC_007946.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1750986 rnfG 3992758 rnfG Escherichia coli UTI89 electron transport complex protein RnfG YP_540830.1 1750366 D 364106 CDS YP_540831.1 91210845 3992759 1750990..1751685 1 NC_007946.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1751685 ydgQ 3992759 ydgQ Escherichia coli UTI89 electron transport complex RsxE subunit YP_540831.1 1750990 D 364106 CDS YP_540832.1 91210846 3992760 1751685..1752320 1 NC_007946.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1752320 nth 3992760 nth Escherichia coli UTI89 endonuclease III YP_540832.1 1751685 D 364106 CDS YP_540833.1 91210847 3992761 1752448..1752648 1 NC_007946.1 hypothetical protein 1752648 3992761 UTI89_C1824 Escherichia coli UTI89 hypothetical protein YP_540833.1 1752448 D 364106 CDS YP_540834.1 91210848 3992762 1752931..1754433 1 NC_007946.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1754433 tppB 3992762 tppB Escherichia coli UTI89 tripeptide transporter permease YP_540834.1 1752931 D 364106 CDS YP_540835.1 91210849 3992763 1754538..1755143 1 NC_007946.1 glutathionine S-transferase 1755143 gst 3992763 gst Escherichia coli UTI89 glutathionine S-transferase YP_540835.1 1754538 D 364106 CDS YP_540836.1 91210850 3992764 complement(1755187..1756050) 1 NC_007946.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1756050 pdxY 3992764 pdxY Escherichia coli UTI89 pyridoxamine kinase YP_540836.1 1755187 R 364106 CDS YP_540837.1 91210851 3992765 complement(1756109..1757395) 1 NC_007946.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1757395 tyrS 3992765 tyrS Escherichia coli UTI89 tyrosyl-tRNA synthetase YP_540837.1 1756109 R 364106 CDS YP_540838.1 91210852 3992766 complement(1757512..1758168) 1 NC_007946.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1758168 pdxH 3992766 pdxH Escherichia coli UTI89 pyridoxamine 5'-phosphate oxidase YP_540838.1 1757512 R 364106 CDS YP_540839.1 91210853 3992767 complement(1758227..1758556) 1 NC_007946.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1758556 ydhA 3992767 ydhA Escherichia coli UTI89 lysozyme inhibitor YP_540839.1 1758227 R 364106 CDS YP_540840.1 91210854 3992768 complement(1758654..1759763) 1 NC_007946.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1759763 anmK 3992768 anmK Escherichia coli UTI89 anhydro-N-acetylmuramic acid kinase YP_540840.1 1758654 R 364106 CDS YP_540841.1 91210855 3992769 1760037..1760504 1 NC_007946.1 outer membrane lipoprotein SlyB 1760504 slyB 3992769 slyB Escherichia coli UTI89 outer membrane lipoprotein SlyB YP_540841.1 1760037 D 364106 CDS YP_540842.1 91210856 3992770 complement(1760551..1760991) 1 NC_007946.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1760991 slyA 3992770 slyA Escherichia coli UTI89 transcriptional regulator SlyA YP_540842.1 1760551 R 364106 CDS YP_540843.1 91210857 3992771 1761186..1761422 1 NC_007946.1 hypothetical protein 1761422 ydhI 3992771 ydhI Escherichia coli UTI89 hypothetical protein YP_540843.1 1761186 D 364106 CDS YP_540844.1 91210858 3992772 1761383..1762282 1 NC_007946.1 hypothetical protein 1762282 ydhJ 3992772 ydhJ Escherichia coli UTI89 hypothetical protein YP_540844.1 1761383 D 364106 CDS YP_540845.1 91210859 3992773 1762282..1764294 1 NC_007946.1 hypothetical protein 1764294 ydhK 3992773 ydhK Escherichia coli UTI89 hypothetical protein YP_540845.1 1762282 D 364106 CDS YP_540846.1 91210860 3992774 complement(1764295..1764867) 1 NC_007946.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1764867 sodC 3992774 sodC Escherichia coli UTI89 superoxide dismutase YP_540846.1 1764295 R 364106 CDS YP_540847.1 91210861 3992775 complement(1764897..1765793) 1 NC_007946.1 oxidoreductase YdhF 1765793 ydhF 3992775 ydhF Escherichia coli UTI89 oxidoreductase YdhF YP_540847.1 1764897 R 364106 CDS YP_540848.1 91210862 3991648 complement(1765842..1766219) 1 NC_007946.1 hypothetical protein 1766219 ydhL 3991648 ydhL Escherichia coli UTI89 hypothetical protein YP_540848.1 1765842 R 364106 CDS YP_540849.1 91210863 3991649 1766184..1766783 1 NC_007946.1 hypothetical protein 1766783 ydhM 3991649 ydhM Escherichia coli UTI89 hypothetical protein YP_540849.1 1766184 D 364106 CDS YP_540850.1 91210864 3991650 1766820..1767917 1 NC_007946.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1767917 nemA 3991650 nemA Escherichia coli UTI89 N-ethylmaleimide reductase YP_540850.1 1766820 D 364106 CDS YP_540851.1 91210865 3991651 1767998..1768405 1 NC_007946.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1768405 gloA 3991651 gloA Escherichia coli UTI89 glyoxalase I YP_540851.1 1767998 D 364106 CDS YP_540852.1 91210866 3991652 1768508..1769155 1 NC_007946.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1769155 rnt 3991652 rnt Escherichia coli UTI89 ribonuclease T YP_540852.1 1768508 D 364106 CDS YP_540853.1 91210867 3991653 1769248..1769391 1 NC_007946.1 hypothetical protein 1769391 3991653 UTI89_C1844 Escherichia coli UTI89 hypothetical protein YP_540853.1 1769248 D 364106 CDS YP_540854.1 91210868 3991654 complement(1769527..1769874) 1 NC_007946.1 hypothetical protein 1769874 ydhD 3991654 ydhD Escherichia coli UTI89 hypothetical protein YP_540854.1 1769527 R 364106 CDS YP_540855.1 91210869 3991655 1770209..1771024 1 NC_007946.1 lipoprotein 1771024 ydhO 3991655 ydhO Escherichia coli UTI89 lipoprotein YP_540855.1 1770209 D 364106 CDS YP_540856.1 91210870 3991656 1771152..1771733 1 NC_007946.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1771733 sodB 3991656 sodB Escherichia coli UTI89 superoxide dismutase YP_540856.1 1771152 D 364106 CDS YP_540857.1 91210871 3991657 complement(1771879..1773048) 1 NC_007946.1 transport protein 1773048 ydhP 3991657 ydhP Escherichia coli UTI89 transport protein YP_540857.1 1771879 R 364106 CDS YP_540858.1 91210872 3991658 1773602..1774627 1 NC_007946.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1774627 purR 3991658 purR Escherichia coli UTI89 DNA-binding transcriptional repressor PurR YP_540858.1 1773602 D 364106 CDS YP_540859.1 91210873 3991659 complement(1774624..1775556) 1 NC_007946.1 DNA-binding transcriptional regulator 1775556 ydhB 3991659 ydhB Escherichia coli UTI89 DNA-binding transcriptional regulator YP_540859.1 1774624 R 364106 CDS YP_540860.1 91210874 3991660 1775669..1776880 1 NC_007946.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1776880 ydhC 3991660 ydhC Escherichia coli UTI89 inner membrane transport protein YdhC YP_540860.1 1775669 D 364106 CDS YP_540861.1 91210875 3991661 1777171..1778319 1 NC_007946.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1778319 cfa 3991661 cfa Escherichia coli UTI89 cyclopropane fatty acyl phospholipid synthase YP_540861.1 1777171 D 364106 CDS YP_540862.1 91210876 3991662 complement(1778359..1779000) 1 NC_007946.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1779000 ribC 3991662 ribC Escherichia coli UTI89 riboflavin synthase subunit alpha YP_540862.1 1778359 R 364106 CDS YP_540863.1 91210877 3991663 1779215..1780588 1 NC_007946.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1780588 ydhE 3991663 ydhE Escherichia coli UTI89 multidrug efflux protein YP_540863.1 1779215 D 364106 CDS YP_540864.1 91210878 3991664 complement(1780629..1781885) 1 NC_007946.1 hypothetical protein 1781885 ydhQ 3991664 ydhQ Escherichia coli UTI89 hypothetical protein YP_540864.1 1780629 R 364106 CDS YP_540866.1 91210880 3993909 1782459..1782764 1 NC_007946.1 hypothetical protein 1782764 3993909 UTI89_C1859 Escherichia coli UTI89 hypothetical protein YP_540866.1 1782459 D 364106 CDS YP_540867.1 91210881 3993910 1782890..1784494 1 NC_007946.1 hypothetical protein 1784494 ydhS 3993910 ydhS Escherichia coli UTI89 hypothetical protein YP_540867.1 1782890 D 364106 CDS YP_540868.1 91210882 3993911 complement(1784506..1785318) 1 NC_007946.1 hypothetical protein 1785318 ydhT 3993911 ydhT Escherichia coli UTI89 hypothetical protein YP_540868.1 1784506 R 364106 CDS YP_540869.1 91210883 3993912 complement(1785322..1786107) 1 NC_007946.1 hypothetical protein 1786107 ydhU 3993912 ydhU Escherichia coli UTI89 hypothetical protein YP_540869.1 1785322 R 364106 CDS YP_540870.1 91210884 3993913 complement(1786104..1786823) 1 NC_007946.1 oxidoreductase Fe-S subunit 1786823 3993913 UTI89_C1863 Escherichia coli UTI89 oxidoreductase Fe-S subunit YP_540870.1 1786104 R 364106 CDS YP_540871.1 91210885 3993914 complement(1786836..1787483) 1 NC_007946.1 hypothetical protein 1787483 ydhW 3993914 ydhW Escherichia coli UTI89 hypothetical protein YP_540871.1 1786836 R 364106 CDS YP_540872.2 162138435 3993915 complement(1787487..1789589) 1 NC_007946.1 oxidoreductase 1789589 ydhV 3993915 ydhV Escherichia coli UTI89 oxidoreductase YP_540872.2 1787487 R 364106 CDS YP_540873.1 91210887 3993916 complement(1789610..1790236) 1 NC_007946.1 hypothetical protein 1790236 ydhY 3993916 ydhY Escherichia coli UTI89 hypothetical protein YP_540873.1 1789610 R 364106 CDS YP_540874.1 91210888 3993917 complement(1790692..1790901) 1 NC_007946.1 hypothetical protein 1790901 ydhZ 3993917 ydhZ Escherichia coli UTI89 hypothetical protein YP_540874.1 1790692 R 364106 CDS YP_540875.1 91210889 3993918 1791242..1792870 1 NC_007946.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1792870 pykF 3993918 pykF Escherichia coli UTI89 pyruvate kinase YP_540875.1 1791242 D 364106 CDS YP_540876.1 91210890 3993919 1793181..1793417 1 NC_007946.1 murein lipoprotein 1793417 lpp 3993919 lpp Escherichia coli UTI89 murein lipoprotein YP_540876.1 1793181 D 364106 CDS YP_540877.1 91210891 3993920 complement(1793480..1794484) 1 NC_007946.1 hypothetical protein 1794484 ynhG 3993920 ynhG Escherichia coli UTI89 hypothetical protein YP_540877.1 1793480 R 364106 CDS YP_540878.1 91210892 3993921 complement(1794633..1795049) 1 NC_007946.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1795049 sufE 3993921 sufE Escherichia coli UTI89 cysteine desufuration protein SufE YP_540878.1 1794633 R 364106 CDS YP_540879.1 91210893 3993922 complement(1795062..1796282) 1 NC_007946.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1796282 sufS 3993922 sufS Escherichia coli UTI89 bifunctional cysteine desulfurase/selenocysteine lyase YP_540879.1 1795062 R 364106 CDS YP_540880.1 91210894 3993923 complement(1796279..1797550) 1 NC_007946.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase 1797550 sufD 3993923 sufD Escherichia coli UTI89 cysteine desulfurase YP_540880.1 1796279 R 364106 CDS YP_540881.1 91210895 3993924 complement(1797525..1798271) 1 NC_007946.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 1798271 sufC 3993924 sufC Escherichia coli UTI89 cysteine desulfurase YP_540881.1 1797525 R 364106 CDS YP_540882.1 91210896 3993925 complement(1798281..1799807) 1 NC_007946.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 1799807 sufB 3993925 sufB Escherichia coli UTI89 cysteine desulfurase YP_540882.1 1798281 R 364106 CDS YP_540883.1 91210897 3992931 complement(1799777..1800145) 1 NC_007946.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1800145 sufA 3992931 sufA Escherichia coli UTI89 iron-sulfur cluster assembly scaffold protein YP_540883.1 1799777 R 364106 CDS YP_540884.1 91210898 3992932 complement(1800694..1800963) 1 NC_007946.1 hypothetical protein 1800963 ydiH 3992932 ydiH Escherichia coli UTI89 hypothetical protein YP_540884.1 1800694 R 364106 CDS YP_540885.1 91210899 3992933 complement(1800982..1801392) 1 NC_007946.1 hypothetical protein 1801392 ydiI 3992933 ydiI Escherichia coli UTI89 hypothetical protein YP_540885.1 1800982 R 364106 CDS YP_540886.1 91210900 3992934 complement(1801389..1804445) 1 NC_007946.1 hypothetical protein 1804445 ydiJ 3992934 ydiJ Escherichia coli UTI89 hypothetical protein YP_540886.1 1801389 R 364106 CDS YP_540887.1 91210901 3992935 1804659..1805771 1 NC_007946.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; hypothetical protein 1805771 ydiK 3992935 ydiK Escherichia coli UTI89 hypothetical protein YP_540887.1 1804659 D 364106 CDS YP_540888.1 91210902 3992936 1806173..1806556 1 NC_007946.1 hypothetical protein 1806556 ydiL 3992936 ydiL Escherichia coli UTI89 hypothetical protein YP_540888.1 1806173 D 364106 CDS YP_540889.1 91210903 3992937 1806656..1807870 1 NC_007946.1 transport protein YdiM 1807870 ydiM 3992937 ydiM Escherichia coli UTI89 transport protein YdiM YP_540889.1 1806656 D 364106 CDS YP_540890.1 91210904 3992938 1808091..1809362 1 NC_007946.1 transport protein YdiN 1809362 ydiN 3992938 ydiN Escherichia coli UTI89 transport protein YdiN YP_540890.1 1808091 D 364106 CDS YP_540891.1 91210905 3992939 1809374..1810240 1 NC_007946.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1810240 ydiB 3992939 ydiB Escherichia coli UTI89 quinate/shikimate dehydrogenase YP_540891.1 1809374 D 364106 CDS YP_540892.1 91210906 3992940 1810271..1811029 1 NC_007946.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1811029 aroD 3992940 aroD Escherichia coli UTI89 3-dehydroquinate dehydratase YP_540892.1 1810271 D 364106 CDS YP_540893.1 91210907 3992941 1811175..1812770 1 NC_007946.1 hypothetical protein 1812770 ydiF 3992941 ydiF Escherichia coli UTI89 hypothetical protein YP_540893.1 1811175 D 364106 CDS YP_540894.2 162138434 3992942 1812784..1813935 1 NC_007946.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1813935 ydiO 3992942 ydiO Escherichia coli UTI89 acyl-CoA dehydrogenase YP_540894.2 1812784 D 364106 CDS YP_540895.1 91210909 3992943 complement(1813978..1814889) 1 NC_007946.1 transcriptional regulator YdiP 1814889 ydiP 3992943 ydiP Escherichia coli UTI89 transcriptional regulator YdiP YP_540895.1 1813978 R 364106 CDS YP_540896.1 91210910 3992944 complement(1814992..1815168) 1 NC_007946.1 hypothetical protein 1815168 3992944 UTI89_C1889 Escherichia coli UTI89 hypothetical protein YP_540896.1 1814992 R 364106 CDS YP_540897.2 162138433 3992945 1815205..1815969 1 NC_007946.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1815969 ydiQ 3992945 ydiQ Escherichia coli UTI89 electron transfer flavoprotein YdiQ YP_540897.2 1815205 D 364106 CDS YP_540898.1 91210912 3992946 1815989..1816927 1 NC_007946.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1816927 ydiR 3992946 ydiR Escherichia coli UTI89 electron transfer flavoprotein subunit YdiR YP_540898.1 1815989 D 364106 CDS YP_540899.1 91210913 3992947 1816982..1818271 1 NC_007946.1 hypothetical protein 1818271 ydiS 3992947 ydiS Escherichia coli UTI89 hypothetical protein YP_540899.1 1816982 D 364106 CDS YP_540900.1 91210914 3992948 1818268..1818561 1 NC_007946.1 ferredoxin-like protein YdiT 1818561 ydiT 3992948 ydiT Escherichia coli UTI89 ferredoxin-like protein YdiT YP_540900.1 1818268 D 364106 CDS YP_540901.1 91210915 3992949 1818564..1820264 1 NC_007946.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1820264 ydiD 3992949 ydiD Escherichia coli UTI89 short chain acyl-CoA synthetase YP_540901.1 1818564 D 364106 CDS YP_540902.1 91210916 3990347 complement(1820321..1822699) 1 NC_007946.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1822699 ppsA 3990347 ppsA Escherichia coli UTI89 phosphoenolpyruvate synthase YP_540902.1 1820321 R 364106 CDS YP_540903.1 91210917 3990348 1823032..1823865 1 NC_007946.1 hypothetical protein 1823865 ydiA 3990348 ydiA Escherichia coli UTI89 hypothetical protein YP_540903.1 1823032 D 364106 CDS YP_540904.1 91210918 3990349 1824022..1825068 1 NC_007946.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1825068 aroH 3990349 aroH Escherichia coli UTI89 phospho-2-dehydro-3-deoxyheptonate aldolase YP_540904.1 1824022 D 364106 CDS YP_540905.1 91210919 3990350 1825173..1825391 1 NC_007946.1 hypothetical protein 1825391 ydiE 3990350 ydiE Escherichia coli UTI89 hypothetical protein YP_540905.1 1825173 D 364106 CDS YP_540906.1 91210920 3990351 complement(1825395..1826831) 1 NC_007946.1 hypothetical protein 1826831 ydiU 3990351 ydiU Escherichia coli UTI89 hypothetical protein YP_540906.1 1825395 R 364106 CDS YP_540907.1 91210921 3990352 complement(1826894..1827607) 1 NC_007946.1 hypothetical protein 1827607 ydiV 3990352 ydiV Escherichia coli UTI89 hypothetical protein YP_540907.1 1826894 R 364106 CDS YP_540908.1 91210922 3990353 complement(1827854..1828318) 1 NC_007946.1 lipoprotein NlpC 1828318 nlpC 3990353 nlpC Escherichia coli UTI89 lipoprotein NlpC YP_540908.1 1827854 R 364106 CDS YP_540909.1 91210923 3990354 complement(1828396..1829145) 1 NC_007946.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1829145 btuD 3990354 btuD Escherichia coli UTI89 vitamin B12-transporter ATPase YP_540909.1 1828396 R 364106 CDS YP_540910.1 91210924 3990355 complement(1829145..1829696) 1 NC_007946.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 1829696 btuE 3990355 btuE Escherichia coli UTI89 glutathione peroxidase YP_540910.1 1829145 R 364106 CDS YP_540911.1 91210925 3990356 complement(1829758..1830738) 1 NC_007946.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1830738 btuC 3990356 btuC Escherichia coli UTI89 vtamin B12-transporter permease YP_540911.1 1829758 R 364106 CDS YP_540912.1 91210926 3990357 complement(1830839..1831138) 1 NC_007946.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1831138 ihfA 3990357 ihfA Escherichia coli UTI89 integration host factor subunit alpha YP_540912.1 1830839 R 364106 CDS YP_540913.1 91210927 3990358 complement(1831143..1833530) 1 NC_007946.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1833530 pheT 3990358 pheT Escherichia coli UTI89 phenylalanyl-tRNA synthetase subunit beta YP_540913.1 1831143 R 364106 CDS YP_540914.2 162138432 3990359 complement(1833545..1834528) 1 NC_007946.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1834528 pheS 3990359 pheS Escherichia coli UTI89 phenylalanyl-tRNA synthetase subunit alpha YP_540914.2 1833545 R 364106 CDS YP_540915.1 91210929 3990360 1834608..1834916 1 NC_007946.1 hypothetical protein 1834916 3990360 UTI89_C1908 Escherichia coli UTI89 hypothetical protein YP_540915.1 1834608 D 364106 CDS YP_540916.1 91210930 3990361 complement(1834979..1835335) 1 NC_007946.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1835335 rplT 3990361 rplT Escherichia coli UTI89 50S ribosomal protein L20 YP_540916.1 1834979 R 364106 CDS YP_540917.1 91210931 3990362 complement(1835388..1835585) 1 NC_007946.1 50S ribosomal protein L35 1835585 rpmI 3990362 rpmI Escherichia coli UTI89 50S ribosomal protein L35 YP_540917.1 1835388 R 364106 CDS YP_540918.1 91210932 3990363 complement(1835682..1836116) 1 NC_007946.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1836116 infC 3990363 infC Escherichia coli UTI89 translation initiation factor IF-3 YP_540918.1 1835682 R 364106 CDS YP_540919.1 91210933 3990364 complement(1836228..1838156) 1 NC_007946.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1838156 thrS 3990364 thrS Escherichia coli UTI89 threonyl-tRNA synthetase YP_540919.1 1836228 R 364106 CDS YP_540920.1 91210934 3990365 1838679..1839113 1 NC_007946.1 hypothetical protein 1839113 3990365 UTI89_C1913 Escherichia coli UTI89 hypothetical protein YP_540920.1 1838679 D 364106 CDS YP_540921.1 91210935 3990366 1839225..1839602 1 NC_007946.1 hypothetical protein 1839602 3990366 UTI89_C1914 Escherichia coli UTI89 hypothetical protein YP_540921.1 1839225 D 364106 CDS YP_540922.1 91210936 3990367 complement(1840040..1840798) 1 NC_007946.1 hypothetical protein 1840798 ydiY 3990367 ydiY Escherichia coli UTI89 hypothetical protein YP_540922.1 1840040 R 364106 CDS YP_540923.1 91210937 3990368 1841081..1842013 1 NC_007946.1 6-phosphofructokinase 1842013 pfkB 3990368 pfkB Escherichia coli UTI89 6-phosphofructokinase YP_540923.1 1841081 D 364106 CDS YP_540924.1 91210938 3990369 complement(1842042..1842419) 1 NC_007946.1 hypothetical protein 1842419 3990369 UTI89_C1917 Escherichia coli UTI89 hypothetical protein YP_540924.1 1842042 R 364106 CDS YP_540925.1 91210939 3990370 1842114..1842404 1 NC_007946.1 hypothetical protein 1842404 ydiZ 3990370 ydiZ Escherichia coli UTI89 hypothetical protein YP_540925.1 1842114 D 364106 CDS YP_540926.1 91210940 3990371 1842510..1843370 1 NC_007946.1 hypothetical protein 1843370 yniA 3990371 yniA Escherichia coli UTI89 hypothetical protein YP_540926.1 1842510 D 364106 CDS YP_540927.1 91210941 3990372 complement(1843411..1843947) 1 NC_007946.1 hypothetical protein 1843947 yniB 3990372 yniB Escherichia coli UTI89 hypothetical protein YP_540927.1 1843411 R 364106 CDS YP_540928.1 91210942 3990373 1844094..1844762 1 NC_007946.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1844762 yniC 3990373 yniC Escherichia coli UTI89 2-deoxyglucose-6-phosphatase YP_540928.1 1844094 D 364106 CDS YP_540929.2 162138431 3990374 1844926..1845516 1 NC_007946.1 hypothetical protein 1845516 3990374 UTI89_C1922 Escherichia coli UTI89 hypothetical protein YP_540929.2 1844926 D 364106 CDS YP_540930.1 91210944 3990375 1845649..1847040 1 NC_007946.1 symporter protein YdjN 1847040 ydjN 3990375 ydjN Escherichia coli UTI89 symporter protein YdjN YP_540930.1 1845649 D 364106 CDS YP_540931.1 91210945 3990376 complement(1847087..1847350) 1 NC_007946.1 cell division modulator 1847350 cedA 3990376 cedA Escherichia coli UTI89 cell division modulator YP_540931.1 1847087 R 364106 CDS YP_540932.1 91210946 3990377 1847533..1849794 1 NC_007946.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1849794 katE 3990377 katE Escherichia coli UTI89 hydroperoxidase II YP_540932.1 1847533 D 364106 CDS YP_540933.1 91210947 3990378 complement(1849840..1850598) 1 NC_007946.1 hypothetical protein 1850598 ydjC 3990378 ydjC Escherichia coli UTI89 hypothetical protein YP_540933.1 1849840 R 364106 CDS YP_540934.1 91210948 3990379 complement(1850611..1852032) 1 NC_007946.1 6-phospho-beta-glucosidase 1852032 celF 3990379 celF Escherichia coli UTI89 6-phospho-beta-glucosidase YP_540934.1 1850611 R 364106 CDS YP_540935.1 91210949 3990380 complement(1852067..1852909) 1 NC_007946.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1852909 celD 3990380 celD Escherichia coli UTI89 DNA-binding transcriptional regulator ChbR YP_540935.1 1852067 R 364106 CDS YP_540936.1 91210950 3990381 complement(1852917..1853267) 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1853267 celC 3990381 celC Escherichia coli UTI89 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_540936.1 1852917 R 364106 CDS YP_540937.1 91210951 3990382 complement(1853318..1854676) 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1854676 celB 3990382 celB Escherichia coli UTI89 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_540937.1 1853318 R 364106 CDS YP_540938.1 91210952 3990383 complement(1854761..1855081) 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1855081 celA 3990383 celA Escherichia coli UTI89 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_540938.1 1854761 R 364106 CDS YP_540939.1 91210953 3990384 complement(1855102..1855362) 1 NC_007946.1 hypothetical protein 1855362 3990384 UTI89_C1932 Escherichia coli UTI89 hypothetical protein YP_540939.1 1855102 R 364106 CDS YP_540940.1 91210954 3990385 complement(1855380..1855718) 1 NC_007946.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1855718 osmE 3990385 osmE Escherichia coli UTI89 DNA-binding transcriptional activator OsmE YP_540940.1 1855380 R 364106 CDS YP_540941.1 91210955 3991590 1855920..1856747 1 NC_007946.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1856747 nadE 3991590 nadE Escherichia coli UTI89 NAD synthetase YP_540941.1 1855920 D 364106 CDS YP_540942.1 91210956 3991591 1856977..1857864 1 NC_007946.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1857864 ydjQ 3991591 ydjQ Escherichia coli UTI89 nucleotide excision repair endonuclease YP_540942.1 1856977 D 364106 CDS YP_540943.1 91210957 3991592 complement(1857824..1858462) 1 NC_007946.1 hypothetical protein 1858462 ydjR 3991592 ydjR Escherichia coli UTI89 hypothetical protein YP_540943.1 1857824 R 364106 CDS YP_540944.1 91210958 3991593 1858590..1859078 1 NC_007946.1 hypothetical protein 1859078 3991593 UTI89_C1937 Escherichia coli UTI89 hypothetical protein YP_540944.1 1858590 D 364106 CDS YP_540945.1 91210959 3991594 complement(1858602..1859087) 1 NC_007946.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein 1859087 spy 3991594 spy Escherichia coli UTI89 periplasmic protein YP_540945.1 1858602 R 364106 CDS YP_540946.1 91210960 3991595 complement(1859417..1860385) 1 NC_007946.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1860385 ydjS 3991595 ydjS Escherichia coli UTI89 succinylglutamate desuccinylase YP_540946.1 1859417 R 364106 CDS YP_540947.1 91210961 3991596 complement(1860378..1861721) 1 NC_007946.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1861721 astB 3991596 astB Escherichia coli UTI89 succinylarginine dihydrolase YP_540947.1 1860378 R 364106 CDS YP_540948.1 91210962 3991597 complement(1861718..1863196) 1 NC_007946.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1863196 astD 3991597 astD Escherichia coli UTI89 succinylglutamic semialdehyde dehydrogenase YP_540948.1 1861718 R 364106 CDS YP_540949.1 91210963 3991598 complement(1863193..1864227) 1 NC_007946.1 arginine succinyltransferase 1864227 astA 3991598 astA Escherichia coli UTI89 arginine succinyltransferase YP_540949.1 1863193 R 364106 CDS YP_540950.1 91210964 3991599 complement(1864224..1865444) 1 NC_007946.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1865444 astC 3991599 astC Escherichia coli UTI89 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_540950.1 1864224 R 364106 CDS YP_540951.1 91210965 3991600 1865707..1865877 1 NC_007946.1 hypothetical protein 1865877 3991600 UTI89_C1944 Escherichia coli UTI89 hypothetical protein YP_540951.1 1865707 D 364106 CDS YP_540952.2 162138430 3991601 1865890..1866696 1 NC_007946.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1866696 xthA 3991601 xthA Escherichia coli UTI89 exonuclease III YP_540952.2 1865890 D 364106 CDS YP_540953.1 91210967 3991602 1866815..1867573 1 NC_007946.1 hypothetical protein 1867573 ydjX 3991602 ydjX Escherichia coli UTI89 hypothetical protein YP_540953.1 1866815 D 364106 CDS YP_540954.1 91210968 3991603 1867416..1868255 1 NC_007946.1 hypothetical protein 1868255 ydjY 3991603 ydjY Escherichia coli UTI89 hypothetical protein YP_540954.1 1867416 D 364106 CDS YP_540955.1 91210969 3991604 1868269..1868976 1 NC_007946.1 hypothetical protein 1868976 ydjZ 3991604 ydjZ Escherichia coli UTI89 hypothetical protein YP_540955.1 1868269 D 364106 CDS YP_540956.1 91210970 3991605 1868976..1869524 1 NC_007946.1 hypothetical protein 1869524 ynjA 3991605 ynjA Escherichia coli UTI89 hypothetical protein YP_540956.1 1868976 D 364106 CDS YP_540957.1 91210971 3991606 1869534..1870700 1 NC_007946.1 ABC transporter solute-binding protein 1870700 ynjB 3991606 ynjB Escherichia coli UTI89 ABC transporter solute-binding protein YP_540957.1 1869534 D 364106 CDS YP_540958.1 91210972 3991607 1870649..1872208 1 NC_007946.1 ABC transporter permease 1872208 ynjC 3991607 ynjC Escherichia coli UTI89 ABC transporter permease YP_540958.1 1870649 D 364106 CDS YP_540959.1 91210973 3991608 1872175..1872861 1 NC_007946.1 ABC transporter ATP-binding protein 1872861 ynjD 3991608 ynjD Escherichia coli UTI89 ABC transporter ATP-binding protein YP_540959.1 1872175 D 364106 CDS YP_540960.1 91210974 3991609 1872913..1874235 1 NC_007946.1 thiosulfate sulfurtransferase 1874235 3991609 UTI89_C1953 Escherichia coli UTI89 thiosulfate sulfurtransferase YP_540960.1 1872913 D 364106 CDS YP_540961.1 91210975 3990651 complement(1874244..1874870) 1 NC_007946.1 hypothetical protein 1874870 ynjF 3990651 ynjF Escherichia coli UTI89 hypothetical protein YP_540961.1 1874244 R 364106 CDS YP_540962.1 91210976 3990652 1874951..1875358 1 NC_007946.1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1875358 ynjG 3990652 ynjG Escherichia coli UTI89 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_540962.1 1874951 D 364106 CDS YP_540963.1 91210977 3990653 complement(1875324..1875596) 1 NC_007946.1 hypothetical protein 1875596 ynjH 3990653 ynjH Escherichia coli UTI89 hypothetical protein YP_540963.1 1875324 R 364106 CDS YP_540964.1 91210978 3990654 1875832..1877175 1 NC_007946.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1877175 gdhA 3990654 gdhA Escherichia coli UTI89 glutamate dehydrogenase YP_540964.1 1875832 D 364106 CDS YP_540965.1 91210979 3990655 complement(1877252..1879207) 1 NC_007946.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1879207 topB 3990655 topB Escherichia coli UTI89 DNA topoisomerase III YP_540965.1 1877252 R 364106 CDS YP_540966.1 91210980 3990656 complement(1879212..1880261) 1 NC_007946.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1880261 selD 3990656 selD Escherichia coli UTI89 selenophosphate synthetase YP_540966.1 1879212 R 364106 CDS YP_540967.1 91210981 3990657 complement(1880372..1880941) 1 NC_007946.1 hypothetical protein 1880941 ydjA 3990657 ydjA Escherichia coli UTI89 hypothetical protein YP_540967.1 1880372 R 364106 CDS YP_540968.1 91210982 3990658 1880977..1881141 1 NC_007946.1 hypothetical protein 1881141 3990658 UTI89_C1961 Escherichia coli UTI89 hypothetical protein YP_540968.1 1880977 D 364106 CDS YP_540969.1 91210983 3990659 1881084..1882940 1 NC_007946.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1882940 sppA 3990659 sppA Escherichia coli UTI89 protease 4 YP_540969.1 1881084 D 364106 CDS YP_540970.1 91210984 3990660 1883107..1884123 1 NC_007946.1 converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 1884123 ansA 3990660 ansA Escherichia coli UTI89 cytoplasmic asparaginase I YP_540970.1 1883107 D 364106 CDS YP_540971.2 162138429 3990661 1884134..1884775 1 NC_007946.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1884775 ydjB 3990661 ydjB Escherichia coli UTI89 nicotinamidase/pyrazinamidase YP_540971.2 1884134 D 364106 CDS YP_540972.1 91210986 3990662 complement(1884868..1886295) 1 NC_007946.1 metabolite transport protein YdjE 1886295 ydjE 3990662 ydjE Escherichia coli UTI89 metabolite transport protein YdjE YP_540972.1 1884868 R 364106 CDS YP_540973.1 91210987 3990663 complement(1886344..1887102) 1 NC_007946.1 DEOR-type transcriptional regulator 1887102 ydjF 3990663 ydjF Escherichia coli UTI89 DEOR-type transcriptional regulator YP_540973.1 1886344 R 364106 CDS YP_540974.1 91210988 3990664 complement(1887239..1888219) 1 NC_007946.1 oxidoreductase YdjG 1888219 ydjG 3990664 ydjG Escherichia coli UTI89 oxidoreductase YdjG YP_540974.1 1887239 R 364106 CDS YP_540975.1 91210989 3990665 complement(1888229..1889197) 1 NC_007946.1 sugar kinase YdjH 1889197 ydjH 3990665 ydjH Escherichia coli UTI89 sugar kinase YdjH YP_540975.1 1888229 R 364106 CDS YP_540976.1 91210990 3990666 complement(1889181..1890017) 1 NC_007946.1 membrane protein YdjI 1890017 ydjI 3990666 ydjI Escherichia coli UTI89 membrane protein YdjI YP_540976.1 1889181 R 364106 CDS YP_540977.1 91210991 3990667 complement(1890038..1891081) 1 NC_007946.1 zinc-type alcohol dehydrogenase-like protein YdjJ 1891081 ydjJ 3990667 ydjJ Escherichia coli UTI89 zinc-type alcohol dehydrogenase-like protein YdjJ YP_540977.1 1890038 R 364106 CDS YP_540978.1 91210992 3990668 complement(1891098..1892477) 1 NC_007946.1 metabolite transport protein YdjK 1892477 ydjK 3990668 ydjK Escherichia coli UTI89 metabolite transport protein YdjK YP_540978.1 1891098 R 364106 CDS YP_540979.1 91210993 3990669 complement(1892504..1893580) 1 NC_007946.1 oxidoreductase 1893580 ydjL 3990669 ydjL Escherichia coli UTI89 oxidoreductase YP_540979.1 1892504 R 364106 CDS YP_540980.1 91210994 3990670 complement(1893950..1894267) 1 NC_007946.1 hypothetical protein 1894267 yeaC 3990670 yeaC Escherichia coli UTI89 hypothetical protein YP_540980.1 1893950 R 364106 CDS YP_540981.1 91210995 3990671 complement(1894264..1894707) 1 NC_007946.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1894707 msrB 3990671 msrB Escherichia coli UTI89 methionine sulfoxide reductase B YP_540981.1 1894264 R 364106 CDS YP_540982.1 91210996 3990672 1895010..1896014 1 NC_007946.1 glyceraldehyde-3-phosphate dehydrogenase A 1896014 gapA 3990672 gapA Escherichia coli UTI89 glyceraldehyde-3-phosphate dehydrogenase A YP_540982.1 1895010 D 364106 CDS YP_540983.1 91210997 3990673 1896077..1896982 1 NC_007946.1 hypothetical protein 1896982 yeaD 3990673 yeaD Escherichia coli UTI89 hypothetical protein YP_540983.1 1896077 D 364106 CDS YP_540984.1 91210998 3990674 complement(1897033..1897932) 1 NC_007946.1 hypothetical protein 1897932 yeaE 3990674 yeaE Escherichia coli UTI89 hypothetical protein YP_540984.1 1897033 R 364106 CDS YP_540985.1 91210999 3990675 complement(1897977..1898723) 1 NC_007946.1 hypothetical protein 1898723 yeaF 3990675 yeaF Escherichia coli UTI89 hypothetical protein YP_540985.1 1897977 R 364106 CDS YP_540986.1 91211000 3990676 1899159..1901093 1 NC_007946.1 hypothetical protein 1901093 yeaG 3990676 yeaG Escherichia coli UTI89 hypothetical protein YP_540986.1 1899159 D 364106 CDS YP_540987.1 91211001 3990677 1901206..1902489 1 NC_007946.1 hypothetical protein 1902489 yeaH 3990677 yeaH Escherichia coli UTI89 hypothetical protein YP_540987.1 1901206 D 364106 CDS YP_540988.1 91211002 3990678 1902636..1904111 1 NC_007946.1 hypothetical protein 1904111 yeaI 3990678 yeaI Escherichia coli UTI89 hypothetical protein YP_540988.1 1902636 D 364106 CDS YP_540989.1 91211003 3990679 1904112..1905782 1 NC_007946.1 hypothetical protein 1905782 yeaJ 3990679 yeaJ Escherichia coli UTI89 hypothetical protein YP_540989.1 1904112 D 364106 CDS YP_540990.1 91211004 3990680 1905825..1906328 1 NC_007946.1 hypothetical protein 1906328 3990680 UTI89_C1983 Escherichia coli UTI89 hypothetical protein YP_540990.1 1905825 D 364106 CDS YP_540991.1 91211005 3990681 complement(1906329..1906481) 1 NC_007946.1 hypothetical protein 1906481 3990681 UTI89_C1984 Escherichia coli UTI89 hypothetical protein YP_540991.1 1906329 R 364106 CDS YP_540992.1 91211006 3990682 1906603..1907049 1 NC_007946.1 hypothetical protein 1907049 yeaL 3990682 yeaL Escherichia coli UTI89 hypothetical protein YP_540992.1 1906603 D 364106 CDS YP_540993.1 91211007 3990683 complement(1907006..1907827) 1 NC_007946.1 transcriptional regulator YeaM 1907827 yeaM 3990683 yeaM Escherichia coli UTI89 transcriptional regulator YeaM YP_540993.1 1907006 R 364106 CDS YP_540994.1 91211008 3990684 1907924..1909105 1 NC_007946.1 amino acid/amine transport protein 1909105 3990684 UTI89_C1987 Escherichia coli UTI89 amino acid/amine transport protein YP_540994.1 1907924 D 364106 CDS YP_540995.1 91211009 3990685 1909160..1909507 1 NC_007946.1 hypothetical protein 1909507 yeaO 3990685 yeaO Escherichia coli UTI89 hypothetical protein YP_540995.1 1909160 D 364106 CDS YP_540997.1 91211011 3990687 complement(1909529..1909783) 1 NC_007946.1 hypothetical protein 1909783 yoaF 3990687 yoaF Escherichia coli UTI89 hypothetical protein YP_540997.1 1909529 R 364106 CDS YP_540998.1 91211012 3990688 1909837..1910991 1 NC_007946.1 hypothetical protein 1910991 yeaP 3990688 yeaP Escherichia coli UTI89 hypothetical protein YP_540998.1 1909837 D 364106 CDS YP_540999.1 91211013 3990689 complement(1911258..1911506) 1 NC_007946.1 hypothetical protein 1911506 yeaQ 3990689 yeaQ Escherichia coli UTI89 hypothetical protein YP_540999.1 1911258 R 364106 CDS YP_541000.1 91211014 3990730 complement(1911518..1911640) 1 NC_007946.1 hypothetical protein 1911640 3990730 UTI89_C1993 Escherichia coli UTI89 hypothetical protein YP_541000.1 1911518 R 364106 CDS YP_541001.1 91211015 3990731 complement(1911654..1911836) 1 NC_007946.1 hypothetical protein 1911836 yoaG 3990731 yoaG Escherichia coli UTI89 hypothetical protein YP_541001.1 1911654 R 364106 CDS YP_541002.1 91211016 3990732 complement(1911840..1912199) 1 NC_007946.1 hypothetical protein 1912199 yeaR 3990732 yeaR Escherichia coli UTI89 hypothetical protein YP_541002.1 1911840 R 364106 CDS YP_541003.1 91211017 3990733 complement(1912372..1913010) 1 NC_007946.1 leucine export protein LeuE 1913010 yeaS 3990733 yeaS Escherichia coli UTI89 leucine export protein LeuE YP_541003.1 1912372 R 364106 CDS YP_541004.1 91211018 3990734 1913293..1913463 1 NC_007946.1 hypothetical protein 1913463 3990734 UTI89_C1997 Escherichia coli UTI89 hypothetical protein YP_541004.1 1913293 D 364106 CDS YP_541005.1 91211019 3990735 complement(1913553..1914680) 1 NC_007946.1 ribonuclease D 1914680 rnd 3990735 rnd Escherichia coli UTI89 ribonuclease D YP_541005.1 1913553 R 364106 CDS YP_541006.1 91211020 3990736 complement(1914750..1916501) 1 NC_007946.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1916501 fadD 3990736 fadD Escherichia coli UTI89 long-chain-fatty-acid--CoA ligase YP_541006.1 1914750 R 364106 CDS YP_541007.1 91211021 3990737 complement(1916640..1917221) 1 NC_007946.1 hypothetical protein 1917221 yeaY 3990737 yeaY Escherichia coli UTI89 hypothetical protein YP_541007.1 1916640 R 364106 CDS YP_541008.1 91211022 3990738 complement(1917261..1917956) 1 NC_007946.1 O-sialoglycoprotein endopeptidase 1917956 yeaZ 3990738 yeaZ Escherichia coli UTI89 O-sialoglycoprotein endopeptidase YP_541008.1 1917261 R 364106 CDS YP_541009.1 91211023 3990739 complement(1918014..1919924) 1 NC_007946.1 hypothetical protein 1919924 3990739 UTI89_C2002 Escherichia coli UTI89 hypothetical protein YP_541009.1 1918014 R 364106 CDS YP_541010.1 91211024 3990740 complement(1919957..1920319) 1 NC_007946.1 hypothetical protein 1920319 3990740 UTI89_C2003 Escherichia coli UTI89 hypothetical protein YP_541010.1 1919957 R 364106 CDS YP_541011.1 91211025 3990741 1920008..1920400 1 NC_007946.1 hypothetical protein 1920400 3990741 UTI89_C2004 Escherichia coli UTI89 hypothetical protein YP_541011.1 1920008 D 364106 CDS YP_541012.1 91211026 3990742 1920762..1921121 1 NC_007946.1 hypothetical protein 1921121 yoaC 3990742 yoaC Escherichia coli UTI89 hypothetical protein YP_541012.1 1920762 D 364106 CDS YP_541013.1 91211027 3990743 1921238..1921402 1 NC_007946.1 hypothetical protein 1921402 3990743 UTI89_C2006 Escherichia coli UTI89 hypothetical protein YP_541013.1 1921238 D 364106 CDS YP_541014.1 91211028 3990744 complement(1921241..1921420) 1 NC_007946.1 hypothetical protein 1921420 yoaH 3990744 yoaH Escherichia coli UTI89 hypothetical protein YP_541014.1 1921241 R 364106 CDS YP_541015.1 91211029 3990745 1921494..1922855 1 NC_007946.1 para-aminobenzoate synthase component I 1922855 pabB 3990745 pabB Escherichia coli UTI89 para-aminobenzoate synthase component I YP_541015.1 1921494 D 364106 CDS YP_541016.1 91211030 3990746 1922859..1923437 1 NC_007946.1 hypothetical protein 1923437 yeaB 3990746 yeaB Escherichia coli UTI89 hypothetical protein YP_541016.1 1922859 D 364106 CDS YP_541017.1 91211031 3990747 1923621..1924985 1 NC_007946.1 L-serine dehydratase 1 1924985 sdaA 3990747 sdaA Escherichia coli UTI89 L-serine dehydratase 1 YP_541017.1 1923621 D 364106 CDS YP_541018.1 91211032 3990748 1925086..1926714 1 NC_007946.1 hypothetical protein 1926714 3990748 UTI89_C2011 Escherichia coli UTI89 hypothetical protein YP_541018.1 1925086 D 364106 CDS YP_541019.1 91211033 3989881 complement(1926718..1928274) 1 NC_007946.1 transmembrane protein 1928274 yoaE 3989881 yoaE Escherichia coli UTI89 transmembrane protein YP_541019.1 1926718 R 364106 CDS YP_541020.1 91211034 3989882 complement(1928262..1928471) 1 NC_007946.1 hypothetical protein 1928471 3989882 UTI89_C2013 Escherichia coli UTI89 hypothetical protein YP_541020.1 1928262 R 364106 CDS YP_541021.1 91211035 3989883 1928737..1929708 1 NC_007946.1 PTS system mannose-specific transporter subunit IIAB 1929708 manX 3989883 manX Escherichia coli UTI89 PTS system mannose-specific transporter subunit IIAB YP_541021.1 1928737 D 364106 CDS YP_541022.1 91211036 3989884 1929771..1930571 1 NC_007946.1 PTS system mannose-specific transporter subunit IIC 1930571 manY 3989884 manY Escherichia coli UTI89 PTS system mannose-specific transporter subunit IIC YP_541022.1 1929771 D 364106 CDS YP_541023.1 91211037 3989885 complement(1929867..1930628) 1 NC_007946.1 hypothetical protein 1930628 3989885 UTI89_C2016 Escherichia coli UTI89 hypothetical protein YP_541023.1 1929867 R 364106 CDS YP_541024.1 91211038 3989886 1930575..1931435 1 NC_007946.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1931435 manZ 3989886 manZ Escherichia coli UTI89 PTS system mannose-specific transporter subunit IID YP_541024.1 1930575 D 364106 CDS YP_541025.1 91211039 3989887 1931490..1931948 1 NC_007946.1 hypothetical protein 1931948 yobD 3989887 yobD Escherichia coli UTI89 hypothetical protein YP_541025.1 1931490 D 364106 CDS YP_541026.1 91211040 3989888 1932323..1932943 1 NC_007946.1 membrane protein YebN; hypothetical protein 1932943 3989888 UTI89_C2019 Escherichia coli UTI89 hypothetical protein YP_541026.1 1932323 D 364106 CDS YP_541027.1 91211041 3989889 complement(1932940..1933749) 1 NC_007946.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase 1933749 rrmA 3989889 rrmA Escherichia coli UTI89 23S rRNA methyltransferase YP_541027.1 1932940 R 364106 CDS YP_541028.1 91211042 3989890 complement(1933915..1934124) 1 NC_007946.1 cold shock-like protein CspC 1934124 cspC 3989890 cspC Escherichia coli UTI89 cold shock-like protein CspC YP_541028.1 1933915 R 364106 CDS YP_541029.1 91211043 3989891 complement(1934137..1934280) 1 NC_007946.1 hypothetical protein 1934280 yobF 3989891 yobF Escherichia coli UTI89 hypothetical protein YP_541029.1 1934137 R 364106 CDS YP_541030.1 91211044 3989892 1934242..1934505 1 NC_007946.1 hypothetical protein 1934505 3989892 UTI89_C2023 Escherichia coli UTI89 hypothetical protein YP_541030.1 1934242 D 364106 CDS YP_541032.1 91211046 3989894 complement(1934951..1935238) 1 NC_007946.1 hypothetical protein 1935238 yebO 3989894 yebO Escherichia coli UTI89 hypothetical protein YP_541032.1 1934951 R 364106 CDS YP_541033.1 91211047 3989895 complement(1935313..1935456) 1 NC_007946.1 synonym: yobG , b1826; hypothetical protein 1935456 mgrB 3989895 mgrB Escherichia coli UTI89 hypothetical protein YP_541033.1 1935313 R 364106 CDS YP_541034.1 91211048 3989896 1935615..1935854 1 NC_007946.1 hypothetical protein 1935854 3989896 UTI89_C2027 Escherichia coli UTI89 hypothetical protein YP_541034.1 1935615 D 364106 CDS YP_541035.1 91211049 3989897 complement(1935998..1936789) 1 NC_007946.1 transcriptional regulator KdgR 1936789 kdgR 3989897 kdgR Escherichia coli UTI89 transcriptional regulator KdgR YP_541035.1 1935998 R 364106 CDS YP_541036.1 91211050 3989898 1936855..1938339 1 NC_007946.1 transport protein YebQ 1938339 yebQ 3989898 yebQ Escherichia coli UTI89 transport protein YebQ YP_541036.1 1936855 D 364106 CDS YP_541037.1 91211051 3989899 complement(1938385..1939266) 1 NC_007946.1 metalloprotease; heat shock protein HtpX 1939266 htpX 3989899 htpX Escherichia coli UTI89 heat shock protein HtpX YP_541037.1 1938385 R 364106 CDS YP_541038.1 91211052 3989900 complement(1939458..1941506) 1 NC_007946.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1941506 prc 3989900 prc Escherichia coli UTI89 carboxy-terminal protease YP_541038.1 1939458 R 364106 CDS YP_541039.1 91211053 3989842 complement(1941526..1942224) 1 NC_007946.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1942224 proQ 3989842 proQ Escherichia coli UTI89 solute/DNA competence effector YP_541039.1 1941526 R 364106 CDS YP_541040.1 91211054 3989843 complement(1942321..1942872) 1 NC_007946.1 hypothetical protein 1942872 3989843 UTI89_C2033 Escherichia coli UTI89 hypothetical protein YP_541040.1 1942321 R 364106 CDS YP_541041.1 91211055 3989844 1942948..1944231 1 NC_007946.1 hypothetical protein 1944231 yebS 3989844 yebS Escherichia coli UTI89 hypothetical protein YP_541041.1 1942948 D 364106 CDS YP_541042.1 91211056 3989845 1944158..1946833 1 NC_007946.1 hypothetical protein 1946833 yebT 3989845 yebT Escherichia coli UTI89 hypothetical protein YP_541042.1 1944158 D 364106 CDS YP_541043.1 91211057 3989846 1946907..1948352 1 NC_007946.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1948352 yebU 3989846 yebU Escherichia coli UTI89 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_541043.1 1946907 D 364106 CDS YP_541044.1 91211058 3989847 1948455..1948706 1 NC_007946.1 hypothetical protein 1948706 yebV 3989847 yebV Escherichia coli UTI89 hypothetical protein YP_541044.1 1948455 D 364106 CDS YP_541045.1 91211059 3989848 1948727..1949002 1 NC_007946.1 hypothetical protein 1949002 yebW 3989848 yebW Escherichia coli UTI89 hypothetical protein YP_541045.1 1948727 D 364106 CDS YP_541046.1 91211060 3989849 complement(1949003..1949662) 1 NC_007946.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1949662 pphA 3989849 pphA Escherichia coli UTI89 serine/threonine protein phosphatase 1 YP_541046.1 1949003 R 364106 CDS YP_541047.1 91211061 3989850 complement(1949884..1950036) 1 NC_007946.1 hypothetical protein 1950036 3989850 UTI89_C2040 Escherichia coli UTI89 hypothetical protein YP_541047.1 1949884 R 364106 CDS YP_541048.1 91211062 3989851 complement(1950054..1950395) 1 NC_007946.1 hypothetical protein 1950395 yebY 3989851 yebY Escherichia coli UTI89 hypothetical protein YP_541048.1 1950054 R 364106 CDS YP_541049.1 91211063 3989852 complement(1950408..1951280) 1 NC_007946.1 hypothetical protein 1951280 yebZ 3989852 yebZ Escherichia coli UTI89 hypothetical protein YP_541049.1 1950408 R 364106 CDS YP_541050.1 91211064 3989853 complement(1951284..1951658) 1 NC_007946.1 hypothetical protein 1951658 yobA 3989853 yobA Escherichia coli UTI89 hypothetical protein YP_541050.1 1951284 R 364106 CDS YP_541051.2 162138428 3989854 1951797..1952027 1 NC_007946.1 DNA polymerase III subunit theta 1952027 holE 3989854 holE Escherichia coli UTI89 DNA polymerase III subunit theta YP_541051.2 1951797 D 364106 CDS YP_541052.1 91211066 3989855 1952129..1952785 1 NC_007946.1 hypothetical protein 1952785 3989855 UTI89_C2045 Escherichia coli UTI89 hypothetical protein YP_541052.1 1952129 D 364106 CDS YP_541053.1 91211067 3989856 1952808..1953470 1 NC_007946.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1953470 exoX 3989856 exoX Escherichia coli UTI89 exodeoxyribonuclease X YP_541053.1 1952808 D 364106 CDS YP_541054.1 91211068 3989857 complement(1953467..1955527) 1 NC_007946.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1955527 ptrB 3989857 ptrB Escherichia coli UTI89 protease 2 YP_541054.1 1953467 R 364106 CDS YP_541055.1 91211069 3989858 1955613..1956215 1 NC_007946.1 hypothetical protein 1956215 3989858 UTI89_C2048 Escherichia coli UTI89 hypothetical protein YP_541055.1 1955613 D 364106 CDS YP_541056.1 91211070 3989859 complement(1955736..1956395) 1 NC_007946.1 hypothetical protein 1956395 yebE 3989859 yebE Escherichia coli UTI89 hypothetical protein YP_541056.1 1955736 R 364106 CDS YP_541057.1 91211071 3989860 complement(1956722..1957090) 1 NC_007946.1 secreted protein; unknown function; hypothetical protein 1957090 yebF 3989860 yebF Escherichia coli UTI89 hypothetical protein YP_541057.1 1956722 R 364106 CDS YP_541058.1 91211072 3989978 complement(1957145..1957435) 1 NC_007946.1 DNA damage-inducible protein YebG 1957435 yebG 3989978 yebG Escherichia coli UTI89 DNA damage-inducible protein YebG YP_541058.1 1957145 R 364106 CDS YP_541059.1 91211073 3989979 1957569..1958747 1 NC_007946.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1958747 purT 3989979 purT Escherichia coli UTI89 phosphoribosylglycinamide formyltransferase 2 YP_541059.1 1957569 D 364106 CDS YP_541060.1 91211074 3989980 complement(1958803..1959444) 1 NC_007946.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1959444 eda 3989980 eda Escherichia coli UTI89 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_541060.1 1958803 R 364106 CDS YP_541061.1 91211075 3989981 complement(1959481..1961358) 1 NC_007946.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1961358 edd 3989981 edd Escherichia coli UTI89 phosphogluconate dehydratase YP_541061.1 1959481 R 364106 CDS YP_541062.1 91211076 3989982 complement(1961527..1963002) 1 NC_007946.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1963002 zwf 3989982 zwf Escherichia coli UTI89 glucose-6-phosphate 1-dehydrogenase YP_541062.1 1961527 R 364106 CDS YP_541063.1 91211077 3989983 complement(1963168..1963317) 1 NC_007946.1 hypothetical protein 1963317 3989983 UTI89_C2056 Escherichia coli UTI89 hypothetical protein YP_541063.1 1963168 R 364106 CDS YP_541064.1 91211078 3989984 1963340..1964209 1 NC_007946.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1964209 yebK 3989984 yebK Escherichia coli UTI89 DNA-binding transcriptional regulator HexR YP_541064.1 1963340 D 364106 CDS YP_541065.1 91211079 3989985 1964196..1965779 1 NC_007946.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1965779 pykA 3989985 pykA Escherichia coli UTI89 pyruvate kinase YP_541065.1 1964196 D 364106 CDS YP_541066.1 91211080 3989986 complement(1965911..1966882) 1 NC_007946.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1966882 msbB 3989986 msbB Escherichia coli UTI89 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_541066.1 1965911 R 364106 CDS YP_541067.1 91211081 3989987 complement(1967001..1968323) 1 NC_007946.1 hypothetical protein 1968323 yebA 3989987 yebA Escherichia coli UTI89 hypothetical protein YP_541067.1 1967001 R 364106 CDS YP_541068.1 91211082 3989988 complement(1968339..1969397) 1 NC_007946.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 1969397 znuA 3989988 znuA Escherichia coli UTI89 high-affinity zinc transporter periplasmic component YP_541068.1 1968339 R 364106 CDS YP_541069.1 91211083 3989989 1969350..1970105 1 NC_007946.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1970105 znuC 3989989 znuC Escherichia coli UTI89 high-affinity zinc transporter ATPase YP_541069.1 1969350 D 364106 CDS YP_541070.1 91211084 3989990 1970102..1970887 1 NC_007946.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 1970887 znuB 3989990 znuB Escherichia coli UTI89 high-affinity zinc transporter membrane component YP_541070.1 1970102 D 364106 CDS YP_541071.1 91211085 3989991 complement(1971104..1972114) 1 NC_007946.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1972114 ruvB 3989991 ruvB Escherichia coli UTI89 Holliday junction DNA helicase RuvB YP_541071.1 1971104 R 364106 CDS YP_541072.1 91211086 3989992 complement(1972123..1972734) 1 NC_007946.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1972734 ruvA 3989992 ruvA Escherichia coli UTI89 Holliday junction DNA helicase RuvA YP_541072.1 1972123 R 364106 CDS YP_541073.2 162138427 3989993 1973010..1973612 1 NC_007946.1 hypothetical protein 1973612 yebB 3989993 yebB Escherichia coli UTI89 hypothetical protein YP_541073.2 1973010 D 364106 CDS YP_541074.1 91211088 3989994 complement(1973614..1974135) 1 NC_007946.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1974135 ruvC 3989994 ruvC Escherichia coli UTI89 Holliday junction resolvase YP_541074.1 1973614 R 364106 CDS YP_541075.1 91211089 3989995 complement(1974170..1974910) 1 NC_007946.1 hypothetical protein 1974910 yebC 3989995 yebC Escherichia coli UTI89 hypothetical protein YP_541075.1 1974170 R 364106 CDS YP_541076.1 91211090 3989996 complement(1974939..1975382) 1 NC_007946.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1975382 ntpA 3989996 ntpA Escherichia coli UTI89 dATP pyrophosphohydrolase YP_541076.1 1974939 R 364106 CDS YP_541077.1 91211091 3989997 complement(1975384..1977156) 1 NC_007946.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1977156 aspS 3989997 aspS Escherichia coli UTI89 aspartyl-tRNA synthetase YP_541077.1 1975384 R 364106 CDS YP_541078.2 162138426 3989664 1977466..1978032 1 NC_007946.1 hypothetical protein 1978032 yecD 3989664 yecD Escherichia coli UTI89 hypothetical protein YP_541078.2 1977466 D 364106 CDS YP_541079.1 91211093 3989665 1978029..1978847 1 NC_007946.1 hypothetical protein 1978847 yecE 3989665 yecE Escherichia coli UTI89 hypothetical protein YP_541079.1 1978029 D 364106 CDS YP_541080.1 91211094 3989666 1978870..1979295 1 NC_007946.1 hypothetical protein 1979295 yecN 3989666 yecN Escherichia coli UTI89 hypothetical protein YP_541080.1 1978870 D 364106 CDS YP_541081.1 91211095 3989667 1979336..1980079 1 NC_007946.1 hypothetical protein 1980079 yecO 3989667 yecO Escherichia coli UTI89 hypothetical protein YP_541081.1 1979336 D 364106 CDS YP_541082.1 91211096 3989668 1980076..1981047 1 NC_007946.1 hypothetical protein 1981047 yecP 3989668 yecP Escherichia coli UTI89 hypothetical protein YP_541082.1 1980076 D 364106 CDS YP_541083.1 91211097 3989669 complement(1981212..1983659) 1 NC_007946.1 trimethylamine-N-oxide reductase 2 1983659 bisZ 3989669 bisZ Escherichia coli UTI89 trimethylamine-N-oxide reductase 2 YP_541083.1 1981212 R 364106 CDS YP_541084.1 91211098 3989670 complement(1983666..1984766) 1 NC_007946.1 cytochrome c-type protein TorY 1984766 yecK 3989670 yecK Escherichia coli UTI89 cytochrome c-type protein TorY YP_541084.1 1983666 R 364106 CDS YP_541085.1 91211099 3989671 complement(1985154..1985900) 1 NC_007946.1 copper homeostasis protein CutC 1985900 3989671 UTI89_C2078 Escherichia coli UTI89 copper homeostasis protein CutC YP_541085.1 1985154 R 364106 CDS YP_541086.1 91211100 3989672 complement(1985914..1986486) 1 NC_007946.1 hypothetical protein 1986486 yecM 3989672 yecM Escherichia coli UTI89 hypothetical protein YP_541086.1 1985914 R 364106 CDS YP_541087.1 91211101 3989673 1986696..1988429 1 NC_007946.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1988429 argS 3989673 argS Escherichia coli UTI89 arginyl-tRNA synthetase YP_541087.1 1986696 D 364106 CDS YP_541088.1 91211102 3989674 complement(1988482..1988874) 1 NC_007946.1 flagellar protein FlhE 1988874 flhE 3989674 flhE Escherichia coli UTI89 flagellar protein FlhE YP_541088.1 1988482 R 364106 CDS YP_541089.2 162138425 3989675 complement(1988874..1990952) 1 NC_007946.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1990952 flhA 3989675 flhA Escherichia coli UTI89 flagellar biosynthesis protein FlhA YP_541089.2 1988874 R 364106 CDS YP_541090.1 91211104 3989676 complement(1990945..1992093) 1 NC_007946.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1992093 flhB 3989676 flhB Escherichia coli UTI89 flagellar biosynthesis protein FlhB YP_541090.1 1990945 R 364106 CDS YP_541091.1 91211105 3989677 1992126..1992272 1 NC_007946.1 hypothetical protein 1992272 3989677 UTI89_C2084 Escherichia coli UTI89 hypothetical protein YP_541091.1 1992126 D 364106 CDS YP_541092.2 162138424 3989678 complement(1992302..1992946) 1 NC_007946.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1992946 cheZ 3989678 cheZ Escherichia coli UTI89 chemotaxis regulator CheZ YP_541092.2 1992302 R 364106 CDS YP_541093.1 91211107 3989679 complement(1992957..1993346) 1 NC_007946.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1993346 cheY 3989679 cheY Escherichia coli UTI89 chemotaxis regulatory protein CheY YP_541093.1 1992957 R 364106 CDS YP_541094.1 91211108 3989680 complement(1993361..1994410) 1 NC_007946.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1994410 cheB 3989680 cheB Escherichia coli UTI89 chemotaxis-specific methylesterase YP_541094.1 1993361 R 364106 CDS YP_541095.1 91211109 3989681 complement(1994413..1995273) 1 NC_007946.1 methylates the MCP; chemotaxis methyltransferase CheR 1995273 cheR 3989681 cheR Escherichia coli UTI89 chemotaxis methyltransferase CheR YP_541095.1 1994413 R 364106 CDS YP_541096.1 91211110 3989682 complement(1995564..1997246) 1 NC_007946.1 methyl-accepting chemotaxis protein II 1997246 tar 3989682 tar Escherichia coli UTI89 methyl-accepting chemotaxis protein II YP_541096.1 1995564 R 364106 CDS YP_541097.1 91211111 3991532 complement(1997370..1997873) 1 NC_007946.1 purine-binding chemotaxis protein 1997873 cheW 3991532 cheW Escherichia coli UTI89 purine-binding chemotaxis protein YP_541097.1 1997370 R 364106 CDS YP_541098.1 91211112 3991533 complement(1997894..1999912) 1 NC_007946.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1999912 cheA 3991533 cheA Escherichia coli UTI89 chemotaxis protein CheA YP_541098.1 1997894 R 364106 CDS YP_541099.1 91211113 3991534 complement(1999863..2000789) 1 NC_007946.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2000789 motB 3991534 motB Escherichia coli UTI89 flagellar motor protein MotB YP_541099.1 1999863 R 364106 CDS YP_541100.1 91211114 3991535 complement(2000786..2001673) 1 NC_007946.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2001673 motA 3991535 motA Escherichia coli UTI89 flagellar motor protein MotA YP_541100.1 2000786 R 364106 CDS YP_541101.1 91211115 3991536 complement(2001800..2002378) 1 NC_007946.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 2002378 flhC 3991536 flhC Escherichia coli UTI89 transcriptional activator FlhC YP_541101.1 2001800 R 364106 CDS YP_541102.1 91211116 3991537 complement(2002381..2002740) 1 NC_007946.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2002740 flhD 3991537 flhD Escherichia coli UTI89 transcriptional activator FlhD YP_541102.1 2002381 R 364106 CDS YP_541103.1 91211117 3991538 2003511..2003939 1 NC_007946.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2003939 yecG 3991538 yecG Escherichia coli UTI89 universal stress protein UspC YP_541103.1 2003511 D 364106 CDS YP_541104.1 91211118 3991539 complement(2003946..2005379) 1 NC_007946.1 trehalose-6-phosphate synthase 2005379 otsA 3991539 otsA Escherichia coli UTI89 trehalose-6-phosphate synthase YP_541104.1 2003946 R 364106 CDS YP_541105.1 91211119 3991540 complement(2005345..2006202) 1 NC_007946.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2006202 otsB 3991540 otsB Escherichia coli UTI89 trehalose-6-phosphate phosphatase YP_541105.1 2005345 R 364106 CDS YP_541106.1 91211120 3991541 complement(2006312..2007301) 1 NC_007946.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2007301 araH 3991541 araH Escherichia coli UTI89 L-arabinose transporter permease YP_541106.1 2006312 R 364106 CDS YP_541107.2 162138423 3991542 complement(2007313..2008827) 1 NC_007946.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2008827 araG 3991542 araG Escherichia coli UTI89 L-arabinose transporter ATP-binding protein YP_541107.2 2007313 R 364106 CDS YP_541108.1 91211122 3991543 complement(2008897..2009937) 1 NC_007946.1 L-arabinose-binding periplasmic protein 2009937 araF 3991543 araF Escherichia coli UTI89 L-arabinose-binding periplasmic protein YP_541108.1 2008897 R 364106 CDS YP_541109.1 91211123 3991544 2010683..2011186 1 NC_007946.1 ferritin 2011186 yecI 3991544 yecI Escherichia coli UTI89 ferritin YP_541109.1 2010683 D 364106 CDS YP_541110.1 91211124 3991545 complement(2011264..2011515) 1 NC_007946.1 hypothetical protein 2011515 yecJ 3991545 yecJ Escherichia coli UTI89 hypothetical protein YP_541110.1 2011264 R 364106 CDS YP_541112.1 91211126 3991547 2011980..2012303 1 NC_007946.1 hypothetical protein 2012303 yecR 3991547 yecR Escherichia coli UTI89 hypothetical protein YP_541112.1 2011980 D 364106 CDS YP_541113.1 91211127 3991548 2012460..2012972 1 NC_007946.1 cytoplasmic iron storage protein; ferritin 2012972 ftnA 3991548 ftnA Escherichia coli UTI89 ferritin YP_541113.1 2012460 D 364106 CDS YP_541114.1 91211128 3991549 complement(2013010..2013249) 1 NC_007946.1 hypothetical protein 2013249 yecH 3991549 yecH Escherichia coli UTI89 hypothetical protein YP_541114.1 2013010 R 364106 CDS YP_541115.1 91211129 3991550 2013440..2014651 1 NC_007946.1 tyrosine-specific transport protein 2014651 tyrP 3991550 tyrP Escherichia coli UTI89 tyrosine-specific transport protein YP_541115.1 2013440 D 364106 CDS YP_541116.1 91211130 3991551 complement(2014702..2015367) 1 NC_007946.1 hypothetical protein 2015367 yecA 3991551 yecA Escherichia coli UTI89 hypothetical protein YP_541116.1 2014702 R 364106 CDS YP_541117.1 91211131 3993201 complement(2016016..2016564) 1 NC_007946.1 phosphatidylglycerophosphate synthetase 2016564 pgsA 3993201 pgsA Escherichia coli UTI89 phosphatidylglycerophosphate synthetase YP_541117.1 2016016 R 364106 CDS YP_541118.1 91211132 3993202 complement(2016621..2018453) 1 NC_007946.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2018453 uvrC 3993202 uvrC Escherichia coli UTI89 excinuclease ABC subunit C YP_541118.1 2016621 R 364106 CDS YP_541119.1 91211133 3993203 complement(2018450..2019106) 1 NC_007946.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2019106 uvrY 3993203 uvrY Escherichia coli UTI89 response regulator YP_541119.1 2018450 R 364106 CDS YP_541120.1 91211134 3993204 2019565..2019789 1 NC_007946.1 hypothetical protein 2019789 yecF 3993204 yecF Escherichia coli UTI89 hypothetical protein YP_541120.1 2019565 D 364106 CDS YP_541121.2 162138422 3993205 complement(2019857..2020579) 1 NC_007946.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2020579 sdiA 3993205 sdiA Escherichia coli UTI89 DNA-binding transcriptional activator SdiA YP_541121.2 2019857 R 364106 CDS YP_541122.1 91211136 3993206 complement(2020809..2021561) 1 NC_007946.1 amino-acid ABC transporter ATP-binding protein YecC 2021561 yecC 3993206 yecC Escherichia coli UTI89 amino-acid ABC transporter ATP-binding protein YecC YP_541122.1 2020809 R 364106 CDS YP_541123.1 91211137 3993207 complement(2021558..2022226) 1 NC_007946.1 transport system permease 2022226 yecS 3993207 yecS Escherichia coli UTI89 transport system permease YP_541123.1 2021558 R 364106 CDS YP_541124.1 91211138 3993208 complement(2022241..2023227) 1 NC_007946.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2023227 3993208 UTI89_C2120 Escherichia coli UTI89 D-cysteine desulfhydrase YP_541124.1 2022241 R 364106 CDS YP_541125.1 91211139 3993209 complement(2023332..2024189) 1 NC_007946.1 cystine transporter subunit 2024189 fliY 3993209 fliY Escherichia coli UTI89 cystine transporter subunit YP_541125.1 2023332 R 364106 CDS YP_541126.1 91211140 3993210 complement(2024220..2024807) 1 NC_007946.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2024807 fliZ 3993210 fliZ Escherichia coli UTI89 flagella biosynthesis protein FliZ YP_541126.1 2024220 R 364106 CDS YP_541127.1 91211141 3993211 complement(2024817..2025536) 1 NC_007946.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2025536 fliA 3993211 fliA Escherichia coli UTI89 flagellar biosynthesis sigma factor YP_541127.1 2024817 R 364106 CDS YP_541128.1 91211142 3993212 complement(2025856..2027613) 1 NC_007946.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2027613 fliC 3993212 fliC Escherichia coli UTI89 flagellin YP_541128.1 2025856 R 364106 CDS YP_541129.1 91211143 3993213 2027879..2029285 1 NC_007946.1 involved in flagellin assembly; flagellar capping protein 2029285 fliD 3993213 fliD Escherichia coli UTI89 flagellar capping protein YP_541129.1 2027879 D 364106 CDS YP_541130.1 91211144 3994762 2029310..2029720 1 NC_007946.1 flagellin specific chaperone; flagellar protein FliS 2029720 fliS 3994762 fliS Escherichia coli UTI89 flagellar protein FliS YP_541130.1 2029310 D 364106 CDS YP_541131.1 91211145 3994763 2029720..2030085 1 NC_007946.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2030085 fliT 3994763 fliT Escherichia coli UTI89 flagellar biosynthesis protein FliT YP_541131.1 2029720 D 364106 CDS YP_541132.1 91211146 3994764 2030163..2031650 1 NC_007946.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2031650 amyA 3994764 amyA Escherichia coli UTI89 cytoplasmic alpha-amylase YP_541132.1 2030163 D 364106 CDS YP_541133.1 91211147 3994765 complement(2031684..2032100) 1 NC_007946.1 hypothetical protein 2032100 yedD 3994765 yedD Escherichia coli UTI89 hypothetical protein YP_541133.1 2031684 R 364106 CDS YP_541134.1 91211148 3994766 2032284..2033489 1 NC_007946.1 hypothetical protein 2033489 yedE 3994766 yedE Escherichia coli UTI89 hypothetical protein YP_541134.1 2032284 D 364106 CDS YP_541135.1 91211149 3994767 2033486..2033719 1 NC_007946.1 hypothetical protein 2033719 yedF 3994767 yedF Escherichia coli UTI89 hypothetical protein YP_541135.1 2033486 D 364106 CDS YP_541136.1 91211150 3994768 2033828..2034496 1 NC_007946.1 hypothetical protein 2034496 yedK 3994768 yedK Escherichia coli UTI89 hypothetical protein YP_541136.1 2033828 D 364106 CDS YP_541137.1 91211151 3994769 2035063..2036091 1 NC_007946.1 porin 2036091 3994769 UTI89_C2133 Escherichia coli UTI89 porin YP_541137.1 2035063 D 364106 CDS YP_541138.1 91211152 3994770 complement(2036593..2037390) 1 NC_007946.1 transcriptional regulator YbcM 2037390 ybcM 3994770 ybcM Escherichia coli UTI89 transcriptional regulator YbcM YP_541138.1 2036593 R 364106 CDS YP_541139.1 91211153 3994771 complement(2037400..2037951) 1 NC_007946.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor 2037951 ybcL 3994771 ybcL Escherichia coli UTI89 kinase inhibitor YP_541139.1 2037400 R 364106 CDS YP_541140.1 91211154 3994772 complement(2038120..2038632) 1 NC_007946.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 2038632 emrE 3994772 emrE Escherichia coli UTI89 multidrug efflux protein YP_541140.1 2038120 R 364106 CDS YP_541141.2 162138421 3994773 complement(2038797..2039111) 1 NC_007946.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2039111 fliE 3994773 fliE Escherichia coli UTI89 flagellar hook-basal body protein FliE YP_541141.2 2038797 R 364106 CDS YP_541142.1 91211156 3994774 2039326..2040984 1 NC_007946.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2040984 fliF 3994774 fliF Escherichia coli UTI89 flagellar MS-ring protein YP_541142.1 2039326 D 364106 CDS YP_541143.1 91211157 3994775 2040977..2041972 1 NC_007946.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2041972 fliG 3994775 fliG Escherichia coli UTI89 flagellar motor switch protein G YP_541143.1 2040977 D 364106 CDS YP_541144.1 91211158 3994776 2041944..2042651 1 NC_007946.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2042651 fliH 3994776 fliH Escherichia coli UTI89 flagellar assembly protein H YP_541144.1 2041944 D 364106 CDS YP_541145.1 91211159 3994777 2042651..2044024 1 NC_007946.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2044024 fliI 3994777 fliI Escherichia coli UTI89 flagellum-specific ATP synthase YP_541145.1 2042651 D 364106 CDS YP_541146.1 91211160 3994778 2044043..2044486 1 NC_007946.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2044486 fliJ 3994778 fliJ Escherichia coli UTI89 flagellar biosynthesis chaperone YP_541146.1 2044043 D 364106 CDS YP_541147.1 91211161 3994779 2044483..2045610 1 NC_007946.1 flagellar hook-length control protein 2045610 fliK 3994779 fliK Escherichia coli UTI89 flagellar hook-length control protein YP_541147.1 2044483 D 364106 CDS YP_541148.1 91211162 3994780 2045715..2046179 1 NC_007946.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2046179 fliL 3994780 fliL Escherichia coli UTI89 flagellar basal body protein FliL YP_541148.1 2045715 D 364106 CDS YP_541149.1 91211163 3994781 2046139..2047188 1 NC_007946.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2047188 fliM 3994781 fliM Escherichia coli UTI89 flagellar motor switch protein FliM YP_541149.1 2046139 D 364106 CDS YP_541150.1 91211164 3994538 2047185..2047598 1 NC_007946.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2047598 fliN 3994538 fliN Escherichia coli UTI89 flagellar motor switch protein FliN YP_541150.1 2047185 D 364106 CDS YP_541151.1 91211165 3994539 2047598..2047966 1 NC_007946.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2047966 fliO 3994539 fliO Escherichia coli UTI89 flagellar biosynthesis protein FliO YP_541151.1 2047598 D 364106 CDS YP_541152.1 91211166 3994540 2047966..2048703 1 NC_007946.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2048703 fliP 3994540 fliP Escherichia coli UTI89 flagellar biosynthesis protein FliP YP_541152.1 2047966 D 364106 CDS YP_541153.1 91211167 3994541 2048713..2048982 1 NC_007946.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2048982 fliQ 3994541 fliQ Escherichia coli UTI89 flagellar biosynthesis protein FliQ YP_541153.1 2048713 D 364106 CDS YP_541154.1 91211168 3994542 2048991..2049776 1 NC_007946.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2049776 fliR 3994542 fliR Escherichia coli UTI89 flagellar biosynthesis protein FliR YP_541154.1 2048991 D 364106 CDS YP_541155.1 91211169 3994543 2050066..2050689 1 NC_007946.1 capsular polysaccharide synthesis DNA-binding transcriptional regulator 2050689 rcsA 3994543 rcsA Escherichia coli UTI89 capsular polysaccharide synthesis DNA-binding transcriptional regulator YP_541155.1 2050066 D 364106 CDS YP_541156.1 91211170 3994544 complement(2050733..2050921) 1 NC_007946.1 transcription is regulated by RpoS and DsrA RNA; hypothetical protein 2050921 dsrB 3994544 dsrB Escherichia coli UTI89 hypothetical protein YP_541156.1 2050733 R 364106 CDS YP_541157.1 91211171 3994545 2050766..2051041 1 NC_007946.1 hypothetical protein 2051041 3994545 UTI89_C2153 Escherichia coli UTI89 hypothetical protein YP_541157.1 2050766 D 364106 CDS YP_541158.1 91211172 3994546 complement(2051018..2051368) 1 NC_007946.1 hypothetical protein 2051368 3994546 UTI89_C2154 Escherichia coli UTI89 hypothetical protein YP_541158.1 2051018 R 364106 CDS YP_541159.1 91211173 3994547 2051069..2051311 1 NC_007946.1 hypothetical protein 2051311 yodD 3994547 yodD Escherichia coli UTI89 hypothetical protein YP_541159.1 2051069 D 364106 CDS YP_541160.1 91211174 3994548 2051609..2052424 1 NC_007946.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2052424 3994548 UTI89_C2156 Escherichia coli UTI89 mannosyl-3-phosphoglycerate phosphatase YP_541160.1 2051609 D 364106 CDS YP_541161.1 91211175 3994549 complement(2052421..2054130) 1 NC_007946.1 hypothetical protein 2054130 3994549 UTI89_C2157 Escherichia coli UTI89 hypothetical protein YP_541161.1 2052421 R 364106 CDS YP_541162.1 91211176 3994550 complement(2054036..2054224) 1 NC_007946.1 hypothetical protein 2054224 3994550 UTI89_C2158 Escherichia coli UTI89 hypothetical protein YP_541162.1 2054036 R 364106 CDS YP_541163.1 91211177 3994551 complement(2054547..2055464) 1 NC_007946.1 hypothetical protein 2055464 3994551 UTI89_C2159 Escherichia coli UTI89 hypothetical protein YP_541163.1 2054547 R 364106 CDS YP_541164.1 91211178 3994552 2055637..2056557 1 NC_007946.1 hypothetical protein 2056557 yedA 3994552 yedA Escherichia coli UTI89 hypothetical protein YP_541164.1 2055637 D 364106 CDS YP_541165.1 91211179 3994553 complement(2056546..2057016) 1 NC_007946.1 DNA mismatch endonuclease, patch repair protein 2057016 vsr 3994553 vsr Escherichia coli UTI89 DNA mismatch endonuclease, patch repair protein YP_541165.1 2056546 R 364106 CDS YP_541166.1 91211180 3994554 complement(2056997..2058415) 1 NC_007946.1 DNA cytosine methylase 2058415 dcm 3994554 dcm Escherichia coli UTI89 DNA cytosine methylase YP_541166.1 2056997 R 364106 CDS YP_541167.1 91211181 3994555 complement(2058482..2059204) 1 NC_007946.1 hypothetical protein 2059204 yedJ 3994555 yedJ Escherichia coli UTI89 hypothetical protein YP_541167.1 2058482 R 364106 CDS YP_541168.1 91211182 3994556 complement(2059217..2059600) 1 NC_007946.1 hypothetical protein 2059600 3994556 UTI89_C2164 Escherichia coli UTI89 hypothetical protein YP_541168.1 2059217 R 364106 CDS YP_541169.1 91211183 3992544 2060118..2061263 1 NC_007946.1 outer membrane protein N 2061263 3992544 UTI89_C2165 Escherichia coli UTI89 outer membrane protein N YP_541169.1 2060118 D 364106 CDS YP_541170.1 91211184 3992545 2061860..2062711 1 NC_007946.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2062711 hchA 3992545 hchA Escherichia coli UTI89 chaperone protein HchA YP_541170.1 2061860 D 364106 CDS YP_541171.1 91211185 3992546 complement(2062818..2064176) 1 NC_007946.1 2-component sensor protein 2064176 yedV 3992546 yedV Escherichia coli UTI89 2-component sensor protein YP_541171.1 2062818 R 364106 CDS YP_541172.2 162138420 3992547 complement(2064176..2064847) 1 NC_007946.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2064847 yedW 3992547 yedW Escherichia coli UTI89 transcriptional regulatory protein YedW YP_541172.2 2064176 R 364106 CDS YP_541173.1 91211187 3992548 2064980..2065393 1 NC_007946.1 hypothetical protein 2065393 3992548 UTI89_C2169 Escherichia coli UTI89 hypothetical protein YP_541173.1 2064980 D 364106 CDS YP_541174.1 91211188 3992549 2065502..2066506 1 NC_007946.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2066506 yedY 3992549 yedY Escherichia coli UTI89 sulfite oxidase subunit YedY YP_541174.1 2065502 D 364106 CDS YP_541175.1 91211189 3992550 2066507..2067142 1 NC_007946.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2067142 yedZ 3992550 yedZ Escherichia coli UTI89 sulfite oxidase subunit YedZ YP_541175.1 2066507 D 364106 CDS YP_541176.1 91211190 3992551 2067399..2068049 1 NC_007946.1 hypothetical protein 2068049 yodA 3992551 yodA Escherichia coli UTI89 hypothetical protein YP_541176.1 2067399 D 364106 CDS YP_541177.1 91211191 3992552 2068085..2068414 1 NC_007946.1 hypothetical protein 2068414 3992552 UTI89_C2173 Escherichia coli UTI89 hypothetical protein YP_541177.1 2068085 D 364106 CDS YP_541178.1 91211192 3992554 2068863..2069699 1 NC_007946.1 hypothetical protein 2069699 3992554 UTI89_C2175 Escherichia coli UTI89 hypothetical protein YP_541178.1 2068863 D 364106 CDS YP_541179.1 91211193 3992556 2070256..2071218 1 NC_007946.1 integrase 2071218 3992556 UTI89_C2177 Escherichia coli UTI89 integrase YP_541179.1 2070256 D 364106 CDS YP_541180.1 91211194 3992557 complement(2071493..2072797) 1 NC_007946.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 2072797 ybtS 3992557 ybtS Escherichia coli UTI89 salicylate synthase Irp9 YP_541180.1 2071493 R 364106 CDS YP_541181.1 91211195 3992558 complement(2072825..2074228) 1 NC_007946.1 hypothetical protein 2074228 ybtX 3992558 ybtX Escherichia coli UTI89 hypothetical protein YP_541181.1 2072825 R 364106 CDS YP_541182.1 91211196 3992559 complement(2074098..2075927) 1 NC_007946.1 ABC transporter protein 2075927 3992559 UTI89_C2180 Escherichia coli UTI89 ABC transporter protein YP_541182.1 2074098 R 364106 CDS YP_541183.1 91211197 3992560 complement(2075887..2077689) 1 NC_007946.1 ABC transporter inner membrane protein 2077689 ybtP 3992560 ybtP Escherichia coli UTI89 ABC transporter inner membrane protein YP_541183.1 2075887 R 364106 CDS YP_541184.1 91211198 3992561 2077856..2078815 1 NC_007946.1 AraC family transcriptional regulator 2078815 3992561 UTI89_C2182 Escherichia coli UTI89 AraC family transcriptional regulator YP_541184.1 2077856 D 364106 CDS YP_541185.1 91211199 3994059 2078988..2085113 1 NC_007946.1 peptide synthetase-like protein 2085113 irp2 3994059 irp2 Escherichia coli UTI89 peptide synthetase-like protein YP_541185.1 2078988 D 364106 CDS YP_541186.1 91211200 3994060 2085201..2094692 1 NC_007946.1 HMWP1 nonribosomal peptide/polyketide synthase 2094692 irp1 3994060 irp1 Escherichia coli UTI89 HMWP1 nonribosomal peptide/polyketide synthase YP_541186.1 2085201 D 364106 CDS YP_541187.1 91211201 3994061 2094689..2095789 1 NC_007946.1 thiazolinyl-S-HMWP1 reductase 2095789 ybtU 3994061 ybtU Escherichia coli UTI89 thiazolinyl-S-HMWP1 reductase YP_541187.1 2094689 D 364106 CDS YP_541188.1 91211202 3994062 2095801..2096589 1 NC_007946.1 hypothetical protein 2096589 ybtT 3994062 ybtT Escherichia coli UTI89 hypothetical protein YP_541188.1 2095801 D 364106 CDS YP_541189.1 91211203 3994063 2096593..2098170 1 NC_007946.1 salicyl-AMP ligase; siderophore biosynthetic protein 2098170 ybtE 3994063 ybtE Escherichia coli UTI89 siderophore biosynthetic protein YP_541189.1 2096593 D 364106 CDS YP_541190.1 91211204 3994064 2098302..2100323 1 NC_007946.1 pesticin receptor 2100323 fyuA 3994064 fyuA Escherichia coli UTI89 pesticin receptor YP_541190.1 2098302 D 364106 CDS YP_541191.1 91211205 3994065 2100917..2101723 1 NC_007946.1 hypothetical protein 2101723 3994065 UTI89_C2189 Escherichia coli UTI89 hypothetical protein YP_541191.1 2100917 D 364106 CDS YP_541192.1 91211206 3994066 2101650..2101820 1 NC_007946.1 hypothetical protein 2101820 3994066 UTI89_C2190 Escherichia coli UTI89 hypothetical protein YP_541192.1 2101650 D 364106 CDS YP_541193.1 91211207 3994067 2101856..2103325 1 NC_007946.1 hypothetical protein 2103325 3994067 UTI89_C2191 Escherichia coli UTI89 hypothetical protein YP_541193.1 2101856 D 364106 CDS YP_541194.1 91211208 3994068 2103338..2103814 1 NC_007946.1 hypothetical protein 2103814 3994068 UTI89_C2192 Escherichia coli UTI89 hypothetical protein YP_541194.1 2103338 D 364106 CDS YP_541195.1 91211209 3994069 complement(2103942..2104994) 1 NC_007946.1 hypothetical protein 2104994 3994069 UTI89_C2193 Escherichia coli UTI89 hypothetical protein YP_541195.1 2103942 R 364106 CDS YP_541196.1 91211210 3994070 2105309..2106625 1 NC_007946.1 shikimate transporter 2106625 shiA 3994070 shiA Escherichia coli UTI89 shikimate transporter YP_541196.1 2105309 D 364106 CDS YP_541197.2 162138419 3994071 2106727..2108181 1 NC_007946.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2108181 amn 3994071 amn Escherichia coli UTI89 AMP nucleosidase YP_541197.2 2106727 D 364106 CDS YP_541198.1 91211212 3994072 2108524..2109240 1 NC_007946.1 hypothetical protein 2109240 yeeN 3994072 yeeN Escherichia coli UTI89 hypothetical protein YP_541198.1 2108524 D 364106 CDS YP_541199.1 91211213 3994073 complement(2109296..2109583) 1 NC_007946.1 hypothetical protein 2109583 3994073 UTI89_C2197 Escherichia coli UTI89 hypothetical protein YP_541199.1 2109296 R 364106 CDS YP_541200.1 91211214 3994075 complement(2109870..2111507) 1 NC_007946.1 hypothetical protein 2111507 yeeO 3994075 yeeO Escherichia coli UTI89 hypothetical protein YP_541200.1 2109870 R 364106 CDS YP_541201.1 91211215 3991630 complement(2111628..2112578) 1 NC_007946.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2112578 cbl 3991630 cbl Escherichia coli UTI89 transcriptional regulator Cbl YP_541201.1 2111628 R 364106 CDS YP_541202.2 162138418 3991631 complement(2112680..2113597) 1 NC_007946.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2113597 nac 3991631 nac Escherichia coli UTI89 nitrogen assimilation transcriptional regulator YP_541202.2 2112680 R 364106 CDS YP_541203.1 91211217 3991633 2114161..2115432 1 NC_007946.1 prophage P4 integrase 2115432 3991633 UTI89_C2204 Escherichia coli UTI89 prophage P4 integrase YP_541203.1 2114161 D 364106 CDS YP_541204.1 91211218 3991634 complement(2115434..2115727) 1 NC_007946.1 hypothetical protein 2115727 3991634 UTI89_C2205 Escherichia coli UTI89 hypothetical protein YP_541204.1 2115434 R 364106 CDS YP_541205.1 91211219 3991635 complement(2115712..2116224) 1 NC_007946.1 hypothetical protein 2116224 3991635 UTI89_C2206 Escherichia coli UTI89 hypothetical protein YP_541205.1 2115712 R 364106 CDS YP_541206.1 91211220 3991636 complement(2116259..2116981) 1 NC_007946.1 thioesterase 2116981 3991636 UTI89_C2207 Escherichia coli UTI89 thioesterase YP_541206.1 2116259 R 364106 CDS YP_541207.1 91211221 3991637 complement(2116974..2118488) 1 NC_007946.1 hypothetical protein 2118488 3991637 UTI89_C2208 Escherichia coli UTI89 hypothetical protein YP_541207.1 2116974 R 364106 CDS YP_541208.1 91211222 3991638 complement(2118501..2120960) 1 NC_007946.1 polyketide synthase 2120960 3991638 UTI89_C2209 Escherichia coli UTI89 polyketide synthase YP_541208.1 2118501 R 364106 CDS YP_541209.1 91211223 3991639 complement(2120991..2125445) 1 NC_007946.1 peptide synthetase 2125445 3991639 UTI89_C2210 Escherichia coli UTI89 peptide synthetase YP_541209.1 2120991 R 364106 CDS YP_541210.1 91211224 3991640 complement(2125355..2126794) 1 NC_007946.1 hypothetical protein 2126794 3991640 UTI89_C2211 Escherichia coli UTI89 hypothetical protein YP_541210.1 2125355 R 364106 CDS YP_541211.1 91211225 3991641 complement(2126856..2128343) 1 NC_007946.1 amidase 2128343 3991641 UTI89_C2212 Escherichia coli UTI89 amidase YP_541211.1 2126856 R 364106 CDS YP_541212.1 91211226 3991642 complement(2128312..2134776) 1 NC_007946.1 peptide synthetase 2134776 3991642 UTI89_C2213 Escherichia coli UTI89 peptide synthetase YP_541212.1 2128312 R 364106 CDS YP_541213.1 91211227 3991643 complement(2134787..2141287) 1 NC_007946.1 peptide synthetase 2141287 3991643 UTI89_C2214 Escherichia coli UTI89 peptide synthetase YP_541213.1 2134787 R 364106 CDS YP_541214.1 91211228 3991644 complement(2141331..2144363) 1 NC_007946.1 polyketide synthase 2144363 3991644 UTI89_C2215 Escherichia coli UTI89 polyketide synthase YP_541214.1 2141331 R 364106 CDS YP_541215.1 91211229 3991645 complement(2144413..2149224) 1 NC_007946.1 hypothetical protein 2149224 3991645 UTI89_C2216 Escherichia coli UTI89 hypothetical protein YP_541215.1 2144413 R 364106 CDS YP_541216.1 91211230 3991646 complement(2149257..2150525) 1 NC_007946.1 transacylase 2150525 3991646 UTI89_C2217 Escherichia coli UTI89 transacylase YP_541216.1 2149257 R 364106 CDS YP_541217.1 91211231 3991647 complement(2150522..2151550) 1 NC_007946.1 acyl-CoA dehydrogenase 2151550 3991647 UTI89_C2218 Escherichia coli UTI89 acyl-CoA dehydrogenase YP_541217.1 2150522 R 364106 CDS YP_541218.1 91211232 3990500 complement(2151656..2151904) 1 NC_007946.1 hypothetical protein 2151904 3990500 UTI89_C2219 Escherichia coli UTI89 hypothetical protein YP_541218.1 2151656 R 364106 CDS YP_541219.1 91211233 3990501 complement(2151934..2152803) 1 NC_007946.1 3-hydroxyacyl-CoA dehydrogenase 2152803 3990501 UTI89_C2220 Escherichia coli UTI89 3-hydroxyacyl-CoA dehydrogenase YP_541219.1 2151934 R 364106 CDS YP_541220.1 91211234 3990502 complement(2152813..2155422) 1 NC_007946.1 polyketide synthase 2155422 3990502 UTI89_C2221 Escherichia coli UTI89 polyketide synthase YP_541220.1 2152813 R 364106 CDS YP_541221.1 91211235 3990503 complement(2155454..2165083) 1 NC_007946.1 peptide/polyketide synthase 2165083 3990503 UTI89_C2222 Escherichia coli UTI89 peptide/polyketide synthase YP_541221.1 2155454 R 364106 CDS YP_541222.1 91211236 3990504 2165689..2166423 1 NC_007946.1 hypothetical protein 2166423 3990504 UTI89_C2223 Escherichia coli UTI89 hypothetical protein YP_541222.1 2165689 D 364106 CDS YP_541223.1 91211237 3990505 2166569..2166835 1 NC_007946.1 transposase 2166835 3990505 UTI89_C2224 Escherichia coli UTI89 transposase YP_541223.1 2166569 D 364106 CDS YP_541224.1 91211238 3990506 2166940..2167419 1 NC_007946.1 transposase 2167419 3990506 UTI89_C2225 Escherichia coli UTI89 transposase YP_541224.1 2166940 D 364106 CDS YP_541225.1 91211239 3990507 2167410..2167637 1 NC_007946.1 transposase 2167637 3990507 UTI89_C2226 Escherichia coli UTI89 transposase YP_541225.1 2167410 D 364106 CDS YP_541226.1 91211240 3990508 complement(2167727..2168152) 1 NC_007946.1 hypothetical protein 2168152 3990508 UTI89_C2227 Escherichia coli UTI89 hypothetical protein YP_541226.1 2167727 R 364106 CDS YP_541227.1 91211241 3990509 complement(2168444..2169379) 1 NC_007946.1 similar to universal stress protein; hypothetical protein 2169379 erfK 3990509 erfK Escherichia coli UTI89 hypothetical protein YP_541227.1 2168444 R 364106 CDS YP_541228.1 91211242 3990510 complement(2169441..2170520) 1 NC_007946.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2170520 cobT 3990510 cobT Escherichia coli UTI89 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_541228.1 2169441 R 364106 CDS YP_541229.1 91211243 3990511 complement(2170532..2171311) 1 NC_007946.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2171311 cobS 3990511 cobS Escherichia coli UTI89 cobalamin synthase YP_541229.1 2170532 R 364106 CDS YP_541230.1 91211244 3990512 complement(2171272..2171817) 1 NC_007946.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase 2171817 cobU 3990512 cobU Escherichia coli UTI89 adenosylcobinamide kinase YP_541230.1 2171272 R 364106 CDS YP_541231.1 91211245 3990513 complement(2171969..2172091) 1 NC_007946.1 hypothetical protein 2172091 3990513 UTI89_C2232 Escherichia coli UTI89 hypothetical protein YP_541231.1 2171969 R 364106 CDS YP_541232.1 91211246 3990514 complement(2172282..2172446) 1 NC_007946.1 hypothetical protein 2172446 3990514 UTI89_C2233 Escherichia coli UTI89 hypothetical protein YP_541232.1 2172282 R 364106 CDS YP_541233.1 91211247 3990515 2173489..2175636 1 NC_007946.1 outer membrane receptor for iron compound or colicin 2175636 3990515 UTI89_C2234 Escherichia coli UTI89 outer membrane receptor for iron compound or colicin YP_541233.1 2173489 D 364106 CDS YP_541234.1 91211248 3990516 complement(2175611..2175895) 1 NC_007946.1 hypothetical protein 2175895 3990516 UTI89_C2235 Escherichia coli UTI89 hypothetical protein YP_541234.1 2175611 R 364106 CDS YP_541235.1 91211249 3990517 2175624..2175752 1 NC_007946.1 hypothetical protein 2175752 3990517 UTI89_C2236 Escherichia coli UTI89 hypothetical protein YP_541235.1 2175624 D 364106 CDS YP_541236.1 91211250 3990518 complement(2176007..2176651) 1 NC_007946.1 hypothetical protein 2176651 ibrB 3990518 ibrB Escherichia coli UTI89 hypothetical protein YP_541236.1 2176007 R 364106 CDS YP_541237.1 91211251 3994442 complement(2176636..2177925) 1 NC_007946.1 hypothetical protein 2177925 ibrA 3994442 ibrA Escherichia coli UTI89 hypothetical protein YP_541237.1 2176636 R 364106 CDS YP_541238.1 91211252 3994443 2178850..2179560 1 NC_007946.1 hypothetical protein 2179560 3994443 UTI89_C2239 Escherichia coli UTI89 hypothetical protein YP_541238.1 2178850 D 364106 CDS YP_541239.1 91211253 3994444 2179574..2180770 1 NC_007946.1 polysaccharide metabolism 2180770 3994444 UTI89_C2240 Escherichia coli UTI89 polysaccharide metabolism YP_541239.1 2179574 D 364106 CDS YP_541240.1 91211254 3994445 2180805..2181329 1 NC_007946.1 transferase 2181329 3994445 UTI89_C2241 Escherichia coli UTI89 transferase YP_541240.1 2180805 D 364106 CDS YP_541241.1 91211255 3994446 2181283..2182104 1 NC_007946.1 hypothetical protein 2182104 3994446 UTI89_C2242 Escherichia coli UTI89 hypothetical protein YP_541241.1 2181283 D 364106 CDS YP_541242.1 91211256 3994447 2182495..2182815 1 NC_007946.1 hypothetical protein 2182815 3994447 UTI89_C2243 Escherichia coli UTI89 hypothetical protein YP_541242.1 2182495 D 364106 CDS YP_541243.1 91211257 3994448 complement(2183044..2184177) 1 NC_007946.1 hypothetical protein 2184177 3994448 UTI89_C2244 Escherichia coli UTI89 hypothetical protein YP_541243.1 2183044 R 364106 CDS YP_541244.1 91211258 3994449 2185780..2186538 1 NC_007946.1 hypothetical protein 2186538 3994449 UTI89_C2245 Escherichia coli UTI89 hypothetical protein YP_541244.1 2185780 D 364106 CDS YP_541245.1 91211259 3994450 2187560..2188594 1 NC_007946.1 phosphotriesterase-related protein 2188594 3994450 UTI89_C2246 Escherichia coli UTI89 phosphotriesterase-related protein YP_541245.1 2187560 D 364106 CDS YP_541246.1 91211260 3994451 complement(2190362..2190625) 1 NC_007946.1 transposase 2190625 3994451 UTI89_C2247 Escherichia coli UTI89 transposase YP_541246.1 2190362 R 364106 CDS YP_541247.1 91211261 3994452 complement(2190909..2191319) 1 NC_007946.1 hypothetical protein 2191319 3994452 UTI89_C2248 Escherichia coli UTI89 hypothetical protein YP_541247.1 2190909 R 364106 CDS YP_541248.1 91211262 3994453 complement(2191307..2191708) 1 NC_007946.1 hypothetical protein 2191708 3994453 UTI89_C2249 Escherichia coli UTI89 hypothetical protein YP_541248.1 2191307 R 364106 CDS YP_541249.1 91211263 3994454 complement(2191874..2192479) 1 NC_007946.1 hypothetical protein 2192479 3994454 UTI89_C2250 Escherichia coli UTI89 hypothetical protein YP_541249.1 2191874 R 364106 CDS YP_541250.1 91211264 3994455 complement(2193083..2193259) 1 NC_007946.1 hypothetical protein 2193259 3994455 UTI89_C2251 Escherichia coli UTI89 hypothetical protein YP_541250.1 2193083 R 364106 CDS YP_541251.1 91211265 3994456 2193210..2193590 1 NC_007946.1 hypothetical protein 2193590 3994456 UTI89_C2252 Escherichia coli UTI89 hypothetical protein YP_541251.1 2193210 D 364106 CDS YP_541252.1 91211266 3994457 2194023..2195219 1 NC_007946.1 transposase 2195219 3994457 UTI89_C2253 Escherichia coli UTI89 transposase YP_541252.1 2194023 D 364106 CDS YP_541253.1 91211267 3994458 2195343..2195621 1 NC_007946.1 hypothetical protein 2195621 3994458 UTI89_C2254 Escherichia coli UTI89 hypothetical protein YP_541253.1 2195343 D 364106 CDS YP_541254.1 91211268 3994459 2195709..2196317 1 NC_007946.1 hypothetical protein 2196317 3994459 UTI89_C2255 Escherichia coli UTI89 hypothetical protein YP_541254.1 2195709 D 364106 CDS YP_541255.1 91211269 3994460 2196746..2197006 1 NC_007946.1 hypothetical protein 2197006 3994460 UTI89_C2256 Escherichia coli UTI89 hypothetical protein YP_541255.1 2196746 D 364106 CDS YP_541256.1 91211270 3994461 complement(2197343..2198125) 1 NC_007946.1 transposase/IS protein 2198125 3994461 UTI89_C2257 Escherichia coli UTI89 transposase/IS protein YP_541256.1 2197343 R 364106 CDS YP_541257.1 91211271 3992392 complement(2198122..2199144) 1 NC_007946.1 transposase 2199144 3992392 UTI89_C2258 Escherichia coli UTI89 transposase YP_541257.1 2198122 R 364106 CDS YP_541258.1 91211272 3992393 2199197..2199469 1 NC_007946.1 transposase 2199469 3992393 UTI89_C2259 Escherichia coli UTI89 transposase YP_541258.1 2199197 D 364106 CDS YP_541259.1 91211273 3992394 complement(2199695..2200072) 1 NC_007946.1 hypothetical protein 2200072 3992394 UTI89_C2260 Escherichia coli UTI89 hypothetical protein YP_541259.1 2199695 R 364106 CDS YP_541260.1 91211274 3992395 2200641..2201813 1 NC_007946.1 hypothetical protein 2201813 3992395 UTI89_C2261 Escherichia coli UTI89 hypothetical protein YP_541260.1 2200641 D 364106 CDS YP_541261.1 91211275 3992396 complement(2202344..2202601) 1 NC_007946.1 hypothetical protein 2202601 3992396 UTI89_C2262 Escherichia coli UTI89 hypothetical protein YP_541261.1 2202344 R 364106 CDS YP_541262.1 91211276 3992397 complement(2202655..2203422) 1 NC_007946.1 ABC transporter 2203422 3992397 UTI89_C2263 Escherichia coli UTI89 ABC transporter YP_541262.1 2202655 R 364106 CDS YP_541263.1 91211277 3992398 complement(2203419..2204477) 1 NC_007946.1 ABC transporter 2204477 3992398 UTI89_C2264 Escherichia coli UTI89 ABC transporter YP_541263.1 2203419 R 364106 CDS YP_541264.1 91211278 3992399 complement(2204496..2205488) 1 NC_007946.1 hypothetical protein 2205488 3992399 UTI89_C2265 Escherichia coli UTI89 hypothetical protein YP_541264.1 2204496 R 364106 CDS YP_541265.1 91211279 3992400 complement(2205496..2207661) 1 NC_007946.1 TonB dependent receptor 2207661 3992400 UTI89_C2266 Escherichia coli UTI89 TonB dependent receptor YP_541265.1 2205496 R 364106 CDS YP_541266.1 91211280 3992401 2208090..2208524 1 NC_007946.1 hypothetical protein 2208524 3992401 UTI89_C2267 Escherichia coli UTI89 hypothetical protein YP_541266.1 2208090 D 364106 CDS YP_541267.1 91211281 3992402 2208742..2211126 1 NC_007946.1 hypothetical protein 2211126 3992402 UTI89_C2268 Escherichia coli UTI89 hypothetical protein YP_541267.1 2208742 D 364106 CDS YP_541268.1 91211282 3992403 2211123..2212028 1 NC_007946.1 hypothetical protein 2212028 3992403 UTI89_C2269 Escherichia coli UTI89 hypothetical protein YP_541268.1 2211123 D 364106 CDS YP_541269.1 91211283 3992404 2212025..2213095 1 NC_007946.1 hypothetical protein 2213095 3992404 UTI89_C2270 Escherichia coli UTI89 hypothetical protein YP_541269.1 2212025 D 364106 CDS YP_541270.1 91211284 3992405 2213123..2213908 1 NC_007946.1 hypothetical protein 2213908 3992405 UTI89_C2271 Escherichia coli UTI89 hypothetical protein YP_541270.1 2213123 D 364106 CDS YP_541271.1 91211285 3992406 2213924..2214334 1 NC_007946.1 hypothetical protein 2214334 3992406 UTI89_C2272 Escherichia coli UTI89 hypothetical protein YP_541271.1 2213924 D 364106 CDS YP_541272.1 91211286 3992407 2214555..2215376 1 NC_007946.1 hypothetical protein 2215376 yafZ2 3992407 yafZ2 Escherichia coli UTI89 hypothetical protein YP_541272.1 2214555 D 364106 CDS YP_541273.1 91211287 3992408 complement(2214561..2215469) 1 NC_007946.1 hypothetical protein 2215469 3992408 UTI89_C2274 Escherichia coli UTI89 hypothetical protein YP_541273.1 2214561 R 364106 CDS YP_541274.1 91211288 3992409 2215567..2216112 1 NC_007946.1 hypothetical protein 2216112 yafX2 3992409 yafX2 Escherichia coli UTI89 hypothetical protein YP_541274.1 2215567 D 364106 CDS YP_541275.1 91211289 3992410 2216127..2216603 1 NC_007946.1 hypothetical protein 2216603 yeeS1 3992410 yeeS1 Escherichia coli UTI89 hypothetical protein YP_541275.1 2216127 D 364106 CDS YP_541276.1 91211290 3992372 2216672..2216893 1 NC_007946.1 hypothetical protein 2216893 yeeT1 3992372 yeeT1 Escherichia coli UTI89 hypothetical protein YP_541276.1 2216672 D 364106 CDS YP_541277.1 91211291 3992373 2216967..2217335 1 NC_007946.1 hypothetical protein 2217335 yeeU1 3992373 yeeU1 Escherichia coli UTI89 hypothetical protein YP_541277.1 2216967 D 364106 CDS YP_541278.1 91211292 3992374 2217424..2217798 1 NC_007946.1 hypothetical protein 2217798 yeeV1 3992374 yeeV1 Escherichia coli UTI89 hypothetical protein YP_541278.1 2217424 D 364106 CDS YP_541279.1 91211293 3992375 2217795..2217989 1 NC_007946.1 hypothetical protein 2217989 yeeW1 3992375 yeeW1 Escherichia coli UTI89 hypothetical protein YP_541279.1 2217795 D 364106 CDS YP_541280.1 91211294 3992376 2218430..2218786 1 NC_007946.1 hypothetical protein 2218786 3992376 UTI89_C2281 Escherichia coli UTI89 hypothetical protein YP_541280.1 2218430 D 364106 CDS YP_541281.1 91211295 3992377 complement(2218887..2219282) 1 NC_007946.1 hypothetical protein 2219282 yeeX 3992377 yeeX Escherichia coli UTI89 hypothetical protein YP_541281.1 2218887 R 364106 CDS YP_541282.1 91211296 3992378 complement(2219388..2220446) 1 NC_007946.1 hypothetical protein 2220446 yeeA 3992378 yeeA Escherichia coli UTI89 hypothetical protein YP_541282.1 2219388 R 364106 CDS YP_541283.1 91211297 3992379 complement(2220644..2221117) 1 NC_007946.1 DNA gyrase inhibitor 2221117 sbmC 3992379 sbmC Escherichia coli UTI89 DNA gyrase inhibitor YP_541283.1 2220644 R 364106 CDS YP_541284.2 162138417 3992380 2222610..2224037 1 NC_007946.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2224037 sbcB 3992380 sbcB Escherichia coli UTI89 exonuclease I YP_541284.2 2222610 D 364106 CDS YP_541285.1 91211299 3992381 complement(2224111..2225475) 1 NC_007946.1 transport protein YeeF 2225475 yeeF 3992381 yeeF Escherichia coli UTI89 transport protein YeeF YP_541285.1 2224111 R 364106 CDS YP_541286.1 91211300 3992382 complement(2225651..2225788) 1 NC_007946.1 hypothetical protein 2225788 3992382 UTI89_C2287 Escherichia coli UTI89 hypothetical protein YP_541286.1 2225651 R 364106 CDS YP_541287.1 91211301 3992383 complement(2225736..2226686) 1 NC_007946.1 transcriptional regulator YeeY 2226686 yeeY 3992383 yeeY Escherichia coli UTI89 transcriptional regulator YeeY YP_541287.1 2225736 R 364106 CDS YP_541288.1 91211302 3992384 complement(2226711..2227535) 1 NC_007946.1 protein YeeZ 2227535 3992384 UTI89_C2289 Escherichia coli UTI89 protein YeeZ YP_541288.1 2226711 R 364106 CDS YP_541289.1 91211303 3992385 complement(2227618..2227872) 1 NC_007946.1 hypothetical protein 2227872 3992385 UTI89_C2290 Escherichia coli UTI89 hypothetical protein YP_541289.1 2227618 R 364106 CDS YP_541290.2 162138416 3992386 complement(2227869..2228120) 1 NC_007946.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2228120 yefM 3992386 yefM Escherichia coli UTI89 antitoxin YefM YP_541290.2 2227869 R 364106 CDS YP_541291.1 91211305 3992387 2228599..2229498 1 NC_007946.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2229498 hisG 3992387 hisG Escherichia coli UTI89 ATP phosphoribosyltransferase YP_541291.1 2228599 D 364106 CDS YP_541292.1 91211306 3992388 2229495..2230808 1 NC_007946.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2230808 hisD 3992388 hisD Escherichia coli UTI89 histidinol dehydrogenase YP_541292.1 2229495 D 364106 CDS YP_541293.1 91211307 3992389 2230805..2231875 1 NC_007946.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2231875 hisC 3992389 hisC Escherichia coli UTI89 histidinol-phosphate aminotransferase YP_541293.1 2230805 D 364106 CDS YP_541294.1 91211308 3992390 2231872..2232942 1 NC_007946.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2232942 hisB 3992390 hisB Escherichia coli UTI89 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_541294.1 2231872 D 364106 CDS YP_541295.1 91211309 3992391 2232942..2233532 1 NC_007946.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2233532 hisH 3992391 hisH Escherichia coli UTI89 imidazole glycerol phosphate synthase subunit HisH YP_541295.1 2232942 D 364106 CDS YP_541296.1 91211310 3990900 2233529..2234269 1 NC_007946.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2234269 hisA 3990900 hisA Escherichia coli UTI89 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_541296.1 2233529 D 364106 CDS YP_541297.1 91211311 3990901 2234251..2235027 1 NC_007946.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2235027 hisF 3990901 hisF Escherichia coli UTI89 imidazole glycerol phosphate synthase subunit HisF YP_541297.1 2234251 D 364106 CDS YP_541298.1 91211312 3990902 2235021..2235632 1 NC_007946.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2235632 hisI 3990902 hisI Escherichia coli UTI89 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_541298.1 2235021 D 364106 CDS YP_541299.1 91211313 3990903 complement(2235818..2236831) 1 NC_007946.1 regulator of length of O-antigen component of lipopolysaccharide chains 2236831 cld 3990903 cld Escherichia coli UTI89 regulator of length of O-antigen component of lipopolysaccharide chains YP_541299.1 2235818 R 364106 CDS YP_541300.1 91211314 3990904 complement(2236941..2238107) 1 NC_007946.1 UDP-glucose 6-dehydrogenase 2238107 ugd 3990904 ugd Escherichia coli UTI89 UDP-glucose 6-dehydrogenase YP_541300.1 2236941 R 364106 CDS YP_541301.1 91211315 3990905 complement(2238354..2239760) 1 NC_007946.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2239760 gnd 3990905 gnd Escherichia coli UTI89 6-phosphogluconate dehydrogenase YP_541301.1 2238354 R 364106 CDS YP_541302.1 91211316 3990906 complement(2239903..2241006) 1 NC_007946.1 galactosyltransferase WbgM 2241006 wbgM 3990906 wbgM Escherichia coli UTI89 galactosyltransferase WbgM YP_541302.1 2239903 R 364106 CDS YP_541303.1 91211317 3990907 complement(2241348..2242454) 1 NC_007946.1 glycosyltransferase WbdM 2242454 wbdM 3990907 wbdM Escherichia coli UTI89 glycosyltransferase WbdM YP_541303.1 2241348 R 364106 CDS YP_541304.1 91211318 3990908 complement(2242451..2243239) 1 NC_007946.1 glycosyltransferase 2243239 3990908 UTI89_C2305 Escherichia coli UTI89 glycosyltransferase YP_541304.1 2242451 R 364106 CDS YP_541305.1 91211319 3990909 complement(2243236..2244171) 1 NC_007946.1 rhamnosyl transferase 2244171 wciP 3990909 wciP Escherichia coli UTI89 rhamnosyl transferase YP_541305.1 2243236 R 364106 CDS YP_541306.1 91211320 3990910 complement(2244153..2245343) 1 NC_007946.1 bacteriophage HK620 O-antigen modification protein 2245343 3990910 UTI89_C2307 Escherichia coli UTI89 bacteriophage HK620 O-antigen modification protein YP_541306.1 2244153 R 364106 CDS YP_541307.1 91211321 3990911 complement(2245400..2246647) 1 NC_007946.1 O-antigen transporter 2246647 rfbE 3990911 rfbE Escherichia coli UTI89 O-antigen transporter YP_541307.1 2245400 R 364106 CDS YP_541308.1 91211322 3990912 complement(2246644..2247201) 1 NC_007946.1 dTDP-4-dehydrorhamnose 3,5-epimerase 2247201 rfbC 3990912 rfbC Escherichia coli UTI89 dTDP-4-dehydrorhamnose 3,5-epimerase YP_541308.1 2246644 R 364106 CDS YP_541309.1 91211323 3990913 complement(2247209..2248084) 1 NC_007946.1 glucose-1-phosphate thymidylyltransferase 2248084 rfbA 3990913 rfbA Escherichia coli UTI89 glucose-1-phosphate thymidylyltransferase YP_541309.1 2247209 R 364106 CDS YP_541310.1 91211324 3990914 complement(2248142..2249041) 1 NC_007946.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 2249041 rfbD 3990914 rfbD Escherichia coli UTI89 dTDP-4-dehydrorhamnose reductase YP_541310.1 2248142 R 364106 CDS YP_541311.1 91211325 3990915 complement(2249041..2250126) 1 NC_007946.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose 4,6 dehydratase 2250126 rfbB 3990915 rfbB Escherichia coli UTI89 dTDP-glucose 4,6 dehydratase YP_541311.1 2249041 R 364106 CDS YP_541312.1 91211326 3990916 2250199..2250444 1 NC_007946.1 hypothetical protein 2250444 3990916 UTI89_C2313 Escherichia coli UTI89 hypothetical protein YP_541312.1 2250199 D 364106 CDS YP_541313.1 91211327 3990917 complement(2250499..2251404) 1 NC_007946.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 2251404 galF 3990917 galF Escherichia coli UTI89 UTP-glucose-1-phosphate uridylyltransferase YP_541313.1 2250499 R 364106 CDS YP_541314.1 91211328 3990918 complement(2251567..2252961) 1 NC_007946.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2252961 wcaM 3990918 wcaM Escherichia coli UTI89 colanic acid biosynthesis protein YP_541314.1 2251567 R 364106 CDS YP_541315.1 91211329 3990861 complement(2252972..2254192) 1 NC_007946.1 colanic acid biosynthesis glycosyltransferase 2254192 wcaL 3990861 wcaL Escherichia coli UTI89 colanic acid biosynthesis glycosyltransferase YP_541315.1 2252972 R 364106 CDS YP_541316.1 91211330 3990862 complement(2254189..2255469) 1 NC_007946.1 pyruvyl transferase 2255469 wcaK 3990862 wcaK Escherichia coli UTI89 pyruvyl transferase YP_541316.1 2254189 R 364106 CDS YP_541317.1 91211331 3990863 complement(2255816..2256127) 1 NC_007946.1 ribonucleoside diphosphage reductase 1 subunit beta, B2 2256127 3990863 UTI89_C2318 Escherichia coli UTI89 ribonucleoside diphosphage reductase 1 subunit beta, B2 YP_541317.1 2255816 R 364106 CDS YP_541318.1 91211332 3990864 complement(2256132..2257610) 1 NC_007946.1 colanic acid exporter 2257610 wzxC 3990864 wzxC Escherichia coli UTI89 colanic acid exporter YP_541318.1 2256132 R 364106 CDS YP_541319.1 91211333 3990865 complement(2257612..2259006) 1 NC_007946.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2259006 wcaJ 3990865 wcaJ Escherichia coli UTI89 UDP-glucose lipid carrier transferase YP_541319.1 2257612 R 364106 CDS YP_541320.1 91211334 3990866 complement(2259060..2260478) 1 NC_007946.1 phosphomannomutase 2260478 cpsG 3990866 cpsG Escherichia coli UTI89 phosphomannomutase YP_541320.1 2259060 R 364106 CDS YP_541321.1 91211335 3990867 2260456..2260614 1 NC_007946.1 hypothetical protein 2260614 3990867 UTI89_C2322 Escherichia coli UTI89 hypothetical protein YP_541321.1 2260456 D 364106 CDS YP_541322.1 91211336 3990868 complement(2260623..2262059) 1 NC_007946.1 mannose-1-phosphate guanylyltransferase 2262059 cpsB 3990868 cpsB Escherichia coli UTI89 mannose-1-phosphate guanylyltransferase YP_541322.1 2260623 R 364106 CDS YP_541323.1 91211337 3990869 complement(2262062..2263285) 1 NC_007946.1 glycosyl transferase 2263285 wcaI 3990869 wcaI Escherichia coli UTI89 glycosyl transferase YP_541323.1 2262062 R 364106 CDS YP_541324.1 91211338 3990870 complement(2263282..2263764) 1 NC_007946.1 mannose-1-phosphate guanylyltransferase 2263764 wcaH 3990870 wcaH Escherichia coli UTI89 mannose-1-phosphate guanylyltransferase YP_541324.1 2263282 R 364106 CDS YP_541325.1 91211339 3990871 complement(2263764..2264729) 1 NC_007946.1 GDP-fucose synthetase chain A 2264729 wcaG 3990871 wcaG Escherichia coli UTI89 GDP-fucose synthetase chain A YP_541325.1 2263764 R 364106 CDS YP_541326.1 91211340 3990872 complement(2264732..2265853) 1 NC_007946.1 subunit of GDP-mannose 4,6-dehydratase 2265853 gmd 3990872 gmd Escherichia coli UTI89 subunit of GDP-mannose 4,6-dehydratase YP_541326.1 2264732 R 364106 CDS YP_541327.1 91211341 3990873 complement(2265880..2266428) 1 NC_007946.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2266428 wcaF 3990873 wcaF Escherichia coli UTI89 colanic acid biosynthesis acetyltransferase WcaF YP_541327.1 2265880 R 364106 CDS YP_541328.1 91211342 3990874 complement(2266444..2267190) 1 NC_007946.1 glycosyl transferase 2267190 wcaE 3990874 wcaE Escherichia coli UTI89 glycosyl transferase YP_541328.1 2266444 R 364106 CDS YP_541329.1 91211343 3990875 complement(2267271..2268563) 1 NC_007946.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2268563 wcaD 3990875 wcaD Escherichia coli UTI89 colanic acid biosynthesis protein YP_541329.1 2267271 R 364106 CDS YP_541330.1 91211344 3990876 complement(2268466..2269683) 1 NC_007946.1 glycosyl transferase 2269683 wcaC 3990876 wcaC Escherichia coli UTI89 glycosyl transferase YP_541330.1 2268466 R 364106 CDS YP_541331.1 91211345 3990877 complement(2269680..2270168) 1 NC_007946.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2270168 wcaB 3990877 wcaB Escherichia coli UTI89 colanic acid biosynthesis acetyltransferase WcaB YP_541331.1 2269680 R 364106 CDS YP_541332.1 91211346 3990878 complement(2270171..2271010) 1 NC_007946.1 glycosyl transferase 2271010 wcaA 3990878 wcaA Escherichia coli UTI89 glycosyl transferase YP_541332.1 2270171 R 364106 CDS YP_541333.2 162138415 3990879 complement(2271139..2273301) 1 NC_007946.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2273301 3990879 UTI89_C2334 Escherichia coli UTI89 tyrosine kinase YP_541333.2 2271139 R 364106 CDS YP_541334.1 91211348 3990880 complement(2273304..2273747) 1 NC_007946.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2273747 wzb 3990880 wzb Escherichia coli UTI89 tyrosine phosphatase YP_541334.1 2273304 R 364106 CDS YP_541335.1 91211349 3990749 complement(2273753..2274892) 1 NC_007946.1 polysaccharide export protein 2274892 wza 3990749 wza Escherichia coli UTI89 polysaccharide export protein YP_541335.1 2273753 R 364106 CDS YP_541336.1 91211350 3990750 2275484..2277133 1 NC_007946.1 transport protein 2277133 3990750 UTI89_C2337 Escherichia coli UTI89 transport protein YP_541336.1 2275484 D 364106 CDS YP_541337.1 91211351 3990751 2277208..2277546 1 NC_007946.1 hypothetical protein 2277546 3990751 UTI89_C2338 Escherichia coli UTI89 hypothetical protein YP_541337.1 2277208 D 364106 CDS YP_541338.1 91211352 3990752 2277536..2277826 1 NC_007946.1 hypothetical protein 2277826 3990752 UTI89_C2339 Escherichia coli UTI89 hypothetical protein YP_541338.1 2277536 D 364106 CDS YP_541339.1 91211353 3990753 complement(2277879..2279732) 1 NC_007946.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2279732 asmA 3990753 asmA Escherichia coli UTI89 assembly protein YP_541339.1 2277879 R 364106 CDS YP_541340.1 91211354 3990754 complement(2279754..2280335) 1 NC_007946.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2280335 dcd 3990754 dcd Escherichia coli UTI89 deoxycytidine triphosphate deaminase YP_541340.1 2279754 R 364106 CDS YP_541341.1 91211355 3990755 complement(2280427..2281131) 1 NC_007946.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2281131 udk 3990755 udk Escherichia coli UTI89 uridine kinase YP_541341.1 2280427 R 364106 CDS YP_541342.1 91211356 3990756 2281386..2284703 1 NC_007946.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2284703 yegE 3990756 yegE Escherichia coli UTI89 sensor protein YP_541342.1 2281386 D 364106 CDS YP_541343.1 91211357 3990757 complement(2284814..2285662) 1 NC_007946.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase 2285662 alkA 3990757 alkA Escherichia coli UTI89 3-methyl-adenine DNA glycosylase YP_541343.1 2284814 R 364106 CDS YP_541344.2 162138414 3990758 2285796..2287148 1 NC_007946.1 chaperone 2287148 yegD 3990758 yegD Escherichia coli UTI89 chaperone YP_541344.2 2285796 D 364106 CDS YP_541345.1 91211359 3990759 complement(2287161..2289110) 1 NC_007946.1 hypothetical protein 2289110 yegI 3990759 yegI Escherichia coli UTI89 hypothetical protein YP_541345.1 2287161 R 364106 CDS YP_541346.1 91211360 3990760 complement(2289098..2289859) 1 NC_007946.1 hypothetical protein 2289859 yegK 3990760 yegK Escherichia coli UTI89 hypothetical protein YP_541346.1 2289098 R 364106 CDS YP_541347.1 91211361 3990761 complement(2289856..2290515) 1 NC_007946.1 hypothetical protein 2290515 yegL 3990761 yegL Escherichia coli UTI89 hypothetical protein YP_541347.1 2289856 R 364106 CDS YP_541348.2 162138413 3990762 2291396..2292643 1 NC_007946.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2292643 yegM 3990762 yegM Escherichia coli UTI89 multidrug efflux system subunit MdtA YP_541348.2 2291396 D 364106 CDS YP_541349.1 91211363 3990763 2292643..2295765 1 NC_007946.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2295765 yegN 3990763 yegN Escherichia coli UTI89 multidrug efflux system subunit MdtB YP_541349.1 2292643 D 364106 CDS YP_541350.1 91211364 3990764 2295766..2298843 1 NC_007946.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2298843 yegO 3990764 yegO Escherichia coli UTI89 multidrug efflux system subunit MdtC YP_541350.1 2295766 D 364106 CDS YP_541351.1 91211365 3990765 2298844..2300259 1 NC_007946.1 multidrug efflux system protein MdtE 2300259 yegB 3990765 yegB Escherichia coli UTI89 multidrug efflux system protein MdtE YP_541351.1 2298844 D 364106 CDS YP_541352.1 91211366 3990766 2300256..2301659 1 NC_007946.1 signal transduction histidine-protein kinase BaeS 2301659 baeS 3990766 baeS Escherichia coli UTI89 signal transduction histidine-protein kinase BaeS YP_541352.1 2300256 D 364106 CDS YP_541353.1 91211367 3990767 2301656..2302378 1 NC_007946.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2302378 baeR 3990767 baeR Escherichia coli UTI89 DNA-binding transcriptional regulator BaeR YP_541353.1 2301656 D 364106 CDS YP_541354.1 91211368 3992103 2302519..2302890 1 NC_007946.1 hypothetical protein 2302890 yegP 3992103 yegP Escherichia coli UTI89 hypothetical protein YP_541354.1 2302519 D 364106 CDS YP_541355.1 91211369 3992104 complement(2303015..2303629) 1 NC_007946.1 hypothetical protein 2303629 3992104 UTI89_C2356 Escherichia coli UTI89 hypothetical protein YP_541355.1 2303015 R 364106 CDS YP_541356.1 91211370 3992105 complement(2303681..2305828) 1 NC_007946.1 hypothetical protein 2305828 3992105 UTI89_C2357 Escherichia coli UTI89 hypothetical protein YP_541356.1 2303681 R 364106 CDS YP_541357.1 91211371 3992106 complement(2305800..2306516) 1 NC_007946.1 hypothetical protein 2306516 3992106 UTI89_C2358 Escherichia coli UTI89 hypothetical protein YP_541357.1 2305800 R 364106 CDS YP_541358.1 91211372 3992107 complement(2306516..2307730) 1 NC_007946.1 hypothetical protein 2307730 3992107 UTI89_C2359 Escherichia coli UTI89 hypothetical protein YP_541358.1 2306516 R 364106 CDS YP_541359.1 91211373 3992108 2308218..2309579 1 NC_007946.1 hypothetical protein 2309579 yegQ 3992108 yegQ Escherichia coli UTI89 hypothetical protein YP_541359.1 2308218 D 364106 CDS YP_541360.1 91211374 3992109 complement(2310079..2310456) 1 NC_007946.1 hypothetical protein 2310456 3992109 UTI89_C2361 Escherichia coli UTI89 hypothetical protein YP_541360.1 2310079 R 364106 CDS YP_541361.1 91211375 3992110 2310812..2311711 1 NC_007946.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2311711 3992110 UTI89_C2362 Escherichia coli UTI89 lipid kinase YP_541361.1 2310812 D 364106 CDS YP_541362.1 91211376 3992111 complement(2311793..2312572) 1 NC_007946.1 hypothetical protein 2312572 3992111 UTI89_C2363 Escherichia coli UTI89 hypothetical protein YP_541362.1 2311793 R 364106 CDS YP_541363.1 91211377 3992112 complement(2312672..2313712) 1 NC_007946.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2313712 gatD 3992112 gatD Escherichia coli UTI89 galactitol-1-phosphate dehydrogenase YP_541363.1 2312672 R 364106 CDS YP_541364.1 91211378 3992113 complement(2313760..2315115) 1 NC_007946.1 PTS system galactitol-specific transporter subunit IIC 2315115 gatC 3992113 gatC Escherichia coli UTI89 PTS system galactitol-specific transporter subunit IIC YP_541364.1 2313760 R 364106 CDS YP_541365.1 91211379 3992114 complement(2315119..2315403) 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2315403 gatB 3992114 gatB Escherichia coli UTI89 PTS system galactitol-specific transporter subunit IIB YP_541365.1 2315119 R 364106 CDS YP_541366.1 91211380 3992115 complement(2315434..2315886) 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2315886 gatA 3992115 gatA Escherichia coli UTI89 PTS system galactitol-specific transporter subunit IIA YP_541366.1 2315434 R 364106 CDS YP_541367.1 91211381 3992116 complement(2315896..2317158) 1 NC_007946.1 tagatose 6-phosphate kinase GatZ 2317158 gatZ 3992116 gatZ Escherichia coli UTI89 tagatose 6-phosphate kinase GatZ YP_541367.1 2315896 R 364106 CDS YP_541368.2 162138412 3992117 complement(2317187..2318041) 1 NC_007946.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2318041 gatY 3992117 gatY Escherichia coli UTI89 tagatose-bisphosphate aldolase YP_541368.2 2317187 R 364106 CDS YP_541369.1 91211383 3992118 2318023..2318280 1 NC_007946.1 hypothetical protein 2318280 3992118 UTI89_C2370 Escherichia coli UTI89 hypothetical protein YP_541369.1 2318023 D 364106 CDS YP_541370.2 162138411 3992119 complement(2318270..2319322) 1 NC_007946.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2319322 3992119 UTI89_C2371 Escherichia coli UTI89 fructose-bisphosphate aldolase YP_541370.2 2318270 R 364106 CDS YP_541371.1 91211385 3992120 2319579..2320856 1 NC_007946.1 nucleoside transporter YegT 2320856 yegT 3992120 yegT Escherichia coli UTI89 nucleoside transporter YegT YP_541371.1 2319579 D 364106 CDS YP_541372.1 91211386 3992121 2320853..2321857 1 NC_007946.1 hypothetical protein 2321857 3992121 UTI89_C2373 Escherichia coli UTI89 hypothetical protein YP_541372.1 2320853 D 364106 CDS YP_541373.1 91211387 3992122 2321854..2322819 1 NC_007946.1 sugar kinase YegV 2322819 yegV 3992122 yegV Escherichia coli UTI89 sugar kinase YegV YP_541373.1 2321854 D 364106 CDS YP_541374.1 91211388 3989645 complement(2322793..2323539) 1 NC_007946.1 transcriptional regulator 2323539 yegW 3989645 yegW Escherichia coli UTI89 transcriptional regulator YP_541374.1 2322793 R 364106 CDS YP_541375.1 91211389 3989646 complement(2323591..2324418) 1 NC_007946.1 hypothetical protein 2324418 yegX 3989646 yegX Escherichia coli UTI89 hypothetical protein YP_541375.1 2323591 R 364106 CDS YP_541376.1 91211390 3989647 complement(2324474..2325274) 1 NC_007946.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2325274 thiD 3989647 thiD Escherichia coli UTI89 phosphomethylpyrimidine kinase YP_541376.1 2324474 R 364106 CDS YP_541377.1 91211391 3989648 complement(2325271..2326059) 1 NC_007946.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2326059 thiM 3989648 thiM Escherichia coli UTI89 hydroxyethylthiazole kinase YP_541377.1 2325271 R 364106 CDS YP_541378.1 91211392 3989649 complement(2326282..2326554) 1 NC_007946.1 hypothetical protein 2326554 yohL 3989649 yohL Escherichia coli UTI89 hypothetical protein YP_541378.1 2326282 R 364106 CDS YP_541379.1 91211393 3989650 2326675..2327499 1 NC_007946.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2327499 yohM 3989650 yohM Escherichia coli UTI89 nickel/cobalt efflux protein RcnA YP_541379.1 2326675 D 364106 CDS YP_541380.1 91211394 3989651 2327538..2328056 1 NC_007946.1 hypothetical protein 2328056 yohN 3989651 yohN Escherichia coli UTI89 hypothetical protein YP_541380.1 2327538 D 364106 CDS YP_541381.1 91211395 3989652 complement(2328138..2329172) 1 NC_007946.1 Yeh fimbiral adhesin YehA 2329172 yehA 3989652 yehA Escherichia coli UTI89 Yeh fimbiral adhesin YehA YP_541381.1 2328138 R 364106 CDS YP_541382.1 91211396 3989653 complement(2329188..2331683) 1 NC_007946.1 outer membrane usher protein YehB 2331683 yehB 3989653 yehB Escherichia coli UTI89 outer membrane usher protein YehB YP_541382.1 2329188 R 364106 CDS YP_541383.1 91211397 3989654 complement(2331684..2332358) 1 NC_007946.1 periplasmic chaperone YehC 2332358 yehC 3989654 yehC Escherichia coli UTI89 periplasmic chaperone YehC YP_541383.1 2331684 R 364106 CDS YP_541384.1 91211398 3989655 complement(2332439..2332981) 1 NC_007946.1 Yeh fimbriae subunit YehD 2332981 yehD 3989655 yehD Escherichia coli UTI89 Yeh fimbriae subunit YehD YP_541384.1 2332439 R 364106 CDS YP_541385.1 91211399 3989656 complement(2333274..2333555) 1 NC_007946.1 hypothetical protein 2333555 yehE 3989656 yehE Escherichia coli UTI89 hypothetical protein YP_541385.1 2333274 R 364106 CDS YP_541386.2 162138410 3989657 complement(2333818..2334927) 1 NC_007946.1 ATPase 2334927 mrp 3989657 mrp Escherichia coli UTI89 ATPase YP_541386.2 2333818 R 364106 CDS YP_541387.1 91211401 3989658 2335050..2337092 1 NC_007946.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2337092 metG 3989658 metG Escherichia coli UTI89 methionyl-tRNA synthetase YP_541387.1 2335050 D 364106 CDS YP_541388.1 91211402 3989659 2337233..2341021 1 NC_007946.1 hypothetical protein 2341021 3989659 UTI89_C2389 Escherichia coli UTI89 hypothetical protein YP_541388.1 2337233 D 364106 CDS YP_541389.1 91211403 3989660 2341031..2344663 1 NC_007946.1 hypothetical protein 2344663 yehI 3989660 yehI Escherichia coli UTI89 hypothetical protein YP_541389.1 2341031 D 364106 CDS YP_541390.1 91211404 3989661 2344724..2344909 1 NC_007946.1 hypothetical protein 2344909 3989661 UTI89_C2391 Escherichia coli UTI89 hypothetical protein YP_541390.1 2344724 D 364106 CDS YP_541391.1 91211405 3989662 2345754..2346908 1 NC_007946.1 hypothetical protein 2346908 yehL 3989662 yehL Escherichia coli UTI89 hypothetical protein YP_541391.1 2345754 D 364106 CDS YP_541392.1 91211406 3989663 2349121..2350320 1 NC_007946.1 hypothetical protein 2350320 yehP 3989663 yehP Escherichia coli UTI89 hypothetical protein YP_541392.1 2349121 D 364106 CDS YP_541393.1 91211407 3989683 2350317..2352320 1 NC_007946.1 hypothetical protein 2352320 yehQ 3989683 yehQ Escherichia coli UTI89 hypothetical protein YP_541393.1 2350317 D 364106 CDS YP_541394.1 91211408 3989684 2352433..2352906 1 NC_007946.1 lipoprotein YehR 2352906 yehR 3989684 yehR Escherichia coli UTI89 lipoprotein YehR YP_541394.1 2352433 D 364106 CDS YP_541395.1 91211409 3989685 complement(2352947..2353474) 1 NC_007946.1 hypothetical protein 2353474 yehS 3989685 yehS Escherichia coli UTI89 hypothetical protein YP_541395.1 2352947 R 364106 CDS YP_541396.1 91211410 3989686 complement(2353464..2354198) 1 NC_007946.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2354198 yehT 3989686 yehT Escherichia coli UTI89 two-component response-regulatory protein YehT YP_541396.1 2353464 R 364106 CDS YP_541397.1 91211411 3989687 complement(2354180..2355880) 1 NC_007946.1 2-component sensor protein 2355880 yehU 3989687 yehU Escherichia coli UTI89 2-component sensor protein YP_541397.1 2354180 R 364106 CDS YP_541398.1 91211412 3989688 2356087..2356818 1 NC_007946.1 transcriptional regulator 2356818 yehV 3989688 yehV Escherichia coli UTI89 transcriptional regulator YP_541398.1 2356087 D 364106 CDS YP_541399.1 91211413 3989689 2356878..2356985 1 NC_007946.1 hypothetical protein 2356985 3989689 UTI89_C2400 Escherichia coli UTI89 hypothetical protein YP_541399.1 2356878 D 364106 CDS YP_541400.1 91211414 3989690 complement(2356966..2357697) 1 NC_007946.1 transport system permease 2357697 yehW 3989690 yehW Escherichia coli UTI89 transport system permease YP_541400.1 2356966 R 364106 CDS YP_541401.1 91211415 3989691 complement(2357702..2358628) 1 NC_007946.1 ABC transporter ATP-binding protein 2358628 yehX 3989691 yehX Escherichia coli UTI89 ABC transporter ATP-binding protein YP_541401.1 2357702 R 364106 CDS YP_541402.1 91211416 3989692 complement(2358621..2359778) 1 NC_007946.1 ABC transporter permease 2359778 yehY 3989692 yehY Escherichia coli UTI89 ABC transporter permease YP_541402.1 2358621 R 364106 CDS YP_541403.1 91211417 3989693 complement(2359785..2360702) 1 NC_007946.1 hypothetical protein 2360702 yehZ 3989693 yehZ Escherichia coli UTI89 hypothetical protein YP_541403.1 2359785 R 364106 CDS YP_541404.1 91211418 3989694 complement(2360733..2360885) 1 NC_007946.1 hypothetical protein 2360885 3989694 UTI89_C2405 Escherichia coli UTI89 hypothetical protein YP_541404.1 2360733 R 364106 CDS YP_541405.1 91211419 3989695 complement(2360892..2363189) 1 NC_007946.1 beta-D-glucoside glucohydrolase 2363189 bglX 3989695 bglX Escherichia coli UTI89 beta-D-glucoside glucohydrolase YP_541405.1 2360892 R 364106 CDS YP_541406.2 162138409 3989696 2363385..2365100 1 NC_007946.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2365100 dld 3989696 dld Escherichia coli UTI89 D-lactate dehydrogenase YP_541406.2 2363385 D 364106 CDS YP_541407.1 91211421 3989697 complement(2365139..2366080) 1 NC_007946.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2366080 pbpG 3989697 pbpG Escherichia coli UTI89 D-alanyl-D-alanine endopeptidase YP_541407.1 2365139 R 364106 CDS YP_541408.1 91211422 3989698 complement(2366245..2366856) 1 NC_007946.1 hypothetical protein 2366856 yohC 3989698 yohC Escherichia coli UTI89 hypothetical protein YP_541408.1 2366245 R 364106 CDS YP_541409.1 91211423 3989699 2366966..2367580 1 NC_007946.1 hypothetical protein 2367580 yohD 3989699 yohD Escherichia coli UTI89 hypothetical protein YP_541409.1 2366966 D 364106 CDS YP_541410.1 91211424 3989700 complement(2367700..2368461) 1 NC_007946.1 acetoin dehydrogenase 2368461 3989700 UTI89_C2411 Escherichia coli UTI89 acetoin dehydrogenase YP_541410.1 2367700 R 364106 CDS YP_541411.2 162138408 3989701 complement(2368514..2369950) 1 NC_007946.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2369950 yohG 3989701 yohG Escherichia coli UTI89 multidrug resistance outer membrane protein MdtQ YP_541411.2 2368514 R 364106 CDS YP_541412.1 91211426 3989702 complement(2370645..2371661) 1 NC_007946.1 tRNA-dihydrouridine synthase C 2371661 yohI 3989702 yohI Escherichia coli UTI89 tRNA-dihydrouridine synthase C YP_541412.1 2370645 R 364106 CDS YP_541413.1 91211427 3990461 2371798..2372232 1 NC_007946.1 hypothetical protein 2372232 yohJ 3990461 yohJ Escherichia coli UTI89 hypothetical protein YP_541413.1 2371798 D 364106 CDS YP_541414.1 91211428 3990462 2372229..2372924 1 NC_007946.1 hypothetical protein 2372924 yohK 3990462 yohK Escherichia coli UTI89 hypothetical protein YP_541414.1 2372229 D 364106 CDS YP_541415.1 91211429 3990463 2373054..2373938 1 NC_007946.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2373938 cdd 3990463 cdd Escherichia coli UTI89 cytidine deaminase YP_541415.1 2373054 D 364106 CDS YP_541416.1 91211430 3990464 2374088..2374807 1 NC_007946.1 hypothetical protein 2374807 sanA 3990464 sanA Escherichia coli UTI89 hypothetical protein YP_541416.1 2374088 D 364106 CDS YP_541417.1 91211431 3990465 2374810..2375049 1 NC_007946.1 hypothetical protein 2375049 3990465 UTI89_C2418 Escherichia coli UTI89 hypothetical protein YP_541417.1 2374810 D 364106 CDS YP_541418.1 91211432 3990466 2375243..2376481 1 NC_007946.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2376481 yeiT 3990466 yeiT Escherichia coli UTI89 oxidoreductase YP_541418.1 2375243 D 364106 CDS YP_541419.1 91211433 3990467 2376469..2377710 1 NC_007946.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2377710 yeiA 3990467 yeiA Escherichia coli UTI89 dihydropyrimidine dehydrogenase YP_541419.1 2376469 D 364106 CDS YP_541420.1 91211434 3990468 complement(2377953..2378963) 1 NC_007946.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 2378963 mglC 3990468 mglC Escherichia coli UTI89 beta-methylgalactoside transporter inner membrane component YP_541420.1 2377953 R 364106 CDS YP_541421.1 91211435 3990469 complement(2378979..2380499) 1 NC_007946.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2380499 mglA 3990469 mglA Escherichia coli UTI89 galactose/methyl galaxtoside transporter ATP-binding protein YP_541421.1 2378979 R 364106 CDS YP_541422.1 91211436 3990470 complement(2380560..2381558) 1 NC_007946.1 galactose-binding transport protein 2381558 mglB 3990470 mglB Escherichia coli UTI89 galactose-binding transport protein YP_541422.1 2380560 R 364106 CDS YP_541423.1 91211437 3990471 complement(2381838..2382884) 1 NC_007946.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2382884 galS 3990471 galS Escherichia coli UTI89 DNA-binding transcriptional regulator GalS YP_541423.1 2381838 R 364106 CDS YP_541424.1 91211438 3990472 2382868..2383071 1 NC_007946.1 hypothetical protein 2383071 3990472 UTI89_C2425 Escherichia coli UTI89 hypothetical protein YP_541424.1 2382868 D 364106 CDS YP_541425.1 91211439 3990473 complement(2383020..2384177) 1 NC_007946.1 hypothetical protein 2384177 3990473 UTI89_C2426 Escherichia coli UTI89 hypothetical protein YP_541425.1 2383020 R 364106 CDS YP_541426.1 91211440 3990474 complement(2384194..2384862) 1 NC_007946.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2384862 folE 3990474 folE Escherichia coli UTI89 GTP cyclohydrolase I YP_541426.1 2384194 R 364106 CDS YP_541427.1 91211441 3990475 2385120..2385956 1 NC_007946.1 hypothetical protein 2385956 yeiG 3990475 yeiG Escherichia coli UTI89 hypothetical protein YP_541427.1 2385120 D 364106 CDS YP_541428.1 91211442 3990476 complement(2385988..2388060) 1 NC_007946.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2388060 cirA 3990476 cirA Escherichia coli UTI89 colicin I receptor YP_541428.1 2385988 R 364106 CDS YP_541429.1 91211443 3990477 complement(2388271..2389740) 1 NC_007946.1 lysine transporter 2389740 lysP 3990477 lysP Escherichia coli UTI89 lysine transporter YP_541429.1 2388271 R 364106 CDS YP_541430.1 91211444 3990478 complement(2389724..2389972) 1 NC_007946.1 hypothetical protein 2389972 3990478 UTI89_C2431 Escherichia coli UTI89 hypothetical protein YP_541430.1 2389724 R 364106 CDS YP_541431.1 91211445 3990479 complement(2389945..2390826) 1 NC_007946.1 DNA-binding transcriptional regulator 2390826 yeiE 3990479 yeiE Escherichia coli UTI89 DNA-binding transcriptional regulator YP_541431.1 2389945 R 364106 CDS YP_541432.1 91211446 3990807 2390925..2391974 1 NC_007946.1 hypothetical protein 2391974 yeiH 3990807 yeiH Escherichia coli UTI89 hypothetical protein YP_541432.1 2390925 D 364106 CDS YP_541433.1 91211447 3990808 2392048..2392905 1 NC_007946.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2392905 nfo 3990808 nfo Escherichia coli UTI89 endonuclease IV YP_541433.1 2392048 D 364106 CDS YP_541434.1 91211448 3990809 2392909..2393997 1 NC_007946.1 hypothetical protein 2393997 yeiI 3990809 yeiI Escherichia coli UTI89 hypothetical protein YP_541434.1 2392909 D 364106 CDS YP_541435.1 91211449 3990810 complement(2394265..2395206) 1 NC_007946.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2395206 rihB 3990810 rihB Escherichia coli UTI89 ribonucleoside hydrolase 2 YP_541435.1 2394265 R 364106 CDS YP_541436.1 91211450 3990811 2395336..2396034 1 NC_007946.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2396034 yeiL 3990811 yeiL Escherichia coli UTI89 DNA-binding transcriptional activator YeiL YP_541436.1 2395336 D 364106 CDS YP_541437.1 91211451 3990812 complement(2396101..2397351) 1 NC_007946.1 transport protein YeiM 2397351 yeiM 3990812 yeiM Escherichia coli UTI89 transport protein YeiM YP_541437.1 2396101 R 364106 CDS YP_541438.1 91211452 3990813 complement(2397445..2398383) 1 NC_007946.1 hypothetical protein 2398383 yeiN 3990813 yeiN Escherichia coli UTI89 hypothetical protein YP_541438.1 2397445 R 364106 CDS YP_541439.1 91211453 3990814 complement(2398371..2399426) 1 NC_007946.1 hypothetical protein 2399426 yeiC 3990814 yeiC Escherichia coli UTI89 hypothetical protein YP_541439.1 2398371 R 364106 CDS YP_541440.1 91211454 3990815 2399528..2399950 1 NC_007946.1 hypothetical protein 2399950 3990815 UTI89_C2441 Escherichia coli UTI89 hypothetical protein YP_541440.1 2399528 D 364106 CDS YP_541441.1 91211455 3990816 complement(2399768..2401459) 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC 2401459 fruA 3990816 fruA Escherichia coli UTI89 PTS system fructose-specific transporter subunits IIBC YP_541441.1 2399768 R 364106 CDS YP_541442.1 91211456 3990817 complement(2401476..2402414) 1 NC_007946.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2402414 fruK 3990817 fruK Escherichia coli UTI89 1-phosphofructokinase YP_541442.1 2401476 R 364106 CDS YP_541443.1 91211457 3990818 complement(2402414..2403544) 1 NC_007946.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 2403544 3990818 UTI89_C2444 Escherichia coli UTI89 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_541443.1 2402414 R 364106 CDS YP_541444.1 91211458 3990819 2403709..2403840 1 NC_007946.1 hypothetical protein 2403840 3990819 UTI89_C2445 Escherichia coli UTI89 hypothetical protein YP_541444.1 2403709 D 364106 CDS YP_541445.1 91211459 3990820 2403911..2405092 1 NC_007946.1 sugar efflux transporter B 2405092 yeiO 3990820 yeiO Escherichia coli UTI89 sugar efflux transporter B YP_541445.1 2403911 D 364106 CDS YP_541446.1 91211460 3990821 complement(2405089..2405277) 1 NC_007946.1 hypothetical protein 2405277 3990821 UTI89_C2447 Escherichia coli UTI89 hypothetical protein YP_541446.1 2405089 R 364106 CDS YP_541447.1 91211461 3990822 2405243..2406070 1 NC_007946.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2406070 yeiP 3990822 yeiP Escherichia coli UTI89 elongation factor P YP_541447.1 2405243 D 364106 CDS YP_541448.1 91211462 3990823 2406284..2407759 1 NC_007946.1 oxidoreductase YeiQ 2407759 yeiQ 3990823 yeiQ Escherichia coli UTI89 oxidoreductase YeiQ YP_541448.1 2406284 D 364106 CDS YP_541449.1 91211463 3990824 2407877..2408863 1 NC_007946.1 hypothetical protein 2408863 yeiR 3990824 yeiR Escherichia coli UTI89 hypothetical protein YP_541449.1 2407877 D 364106 CDS YP_541450.1 91211464 3990825 2408866..2409615 1 NC_007946.1 hypothetical protein 2409615 3990825 UTI89_C2451 Escherichia coli UTI89 hypothetical protein YP_541450.1 2408866 D 364106 CDS YP_541451.1 91211465 3990826 2410027..2410593 1 NC_007946.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2410593 spr 3990826 spr Escherichia coli UTI89 outer membrane lipoprotein YP_541451.1 2410027 D 364106 CDS YP_541452.1 91211466 3990386 2410774..2412330 1 NC_007946.1 hypothetical protein 2412330 rtn 3990386 rtn Escherichia coli UTI89 hypothetical protein YP_541452.1 2410774 D 364106 CDS YP_541453.1 91211467 3990387 2412406..2414226 1 NC_007946.1 hypothetical protein 2414226 yejA 3990387 yejA Escherichia coli UTI89 hypothetical protein YP_541453.1 2412406 D 364106 CDS YP_541454.1 91211468 3990388 2414227..2415321 1 NC_007946.1 oligopeptide transport system permease OppB 2415321 3990388 UTI89_C2455 Escherichia coli UTI89 oligopeptide transport system permease OppB YP_541454.1 2414227 D 364106 CDS YP_541455.1 91211469 3990389 2415321..2416346 1 NC_007946.1 transport system permease 2416346 yejE 3990389 yejE Escherichia coli UTI89 transport system permease YP_541455.1 2415321 D 364106 CDS YP_541456.1 91211470 3990390 2416348..2417937 1 NC_007946.1 ABC transporter ATP-binding protein 2417937 yejF 3990390 yejF Escherichia coli UTI89 ABC transporter ATP-binding protein YP_541456.1 2416348 D 364106 CDS YP_541457.1 91211471 3990391 complement(2417941..2418285) 1 NC_007946.1 hypothetical protein 2418285 yejG 3990391 yejG Escherichia coli UTI89 hypothetical protein YP_541457.1 2417941 R 364106 CDS YP_541458.1 91211472 3990392 complement(2418619..2419809) 1 NC_007946.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 2419809 bcr 3990392 bcr Escherichia coli UTI89 bicyclomycin/multidrug efflux system YP_541458.1 2418619 R 364106 CDS YP_541459.2 162138407 3990393 complement(2419837..2420532) 1 NC_007946.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2420532 rsuA 3990393 rsuA Escherichia coli UTI89 16S rRNA pseudouridylate synthase A YP_541459.2 2419837 R 364106 CDS YP_541460.1 91211474 3990394 2420682..2422442 1 NC_007946.1 hypothetical protein 2422442 yejH 3990394 yejH Escherichia coli UTI89 hypothetical protein YP_541460.1 2420682 D 364106 CDS YP_541462.1 91211476 3990396 complement(2422552..2422983) 1 NC_007946.1 hypothetical protein 2422983 3990396 UTI89_C2463 Escherichia coli UTI89 hypothetical protein YP_541462.1 2422552 R 364106 CDS YP_541461.2 162138406 3990395 2422567..2422851 1 NC_007946.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2422851 rplY 3990395 rplY Escherichia coli UTI89 50S ribosomal protein L25 YP_541461.2 2422567 D 364106 CDS YP_541463.1 91211477 3990397 complement(2422990..2423997) 1 NC_007946.1 nucleoid-associated protein NdpA 2423997 yejK 3990397 yejK Escherichia coli UTI89 nucleoid-associated protein NdpA YP_541463.1 2422990 R 364106 CDS YP_541464.1 91211478 3990398 2424179..2424406 1 NC_007946.1 hypothetical protein 2424406 yejL 3990398 yejL Escherichia coli UTI89 hypothetical protein YP_541464.1 2424179 D 364106 CDS YP_541465.1 91211479 3990399 2424426..2426186 1 NC_007946.1 sulfatase 2426186 yejM 3990399 yejM Escherichia coli UTI89 sulfatase YP_541465.1 2424426 D 364106 CDS YP_541466.1 91211480 3990401 complement(2426439..2426594) 1 NC_007946.1 hypothetical protein 2426594 3990401 UTI89_C2468 Escherichia coli UTI89 hypothetical protein YP_541466.1 2426439 R 364106 CDS YP_541467.1 91211481 3990402 complement(2427033..2427236) 1 NC_007946.1 outer membrane protein YejO 2427236 yejO 3990402 yejO Escherichia coli UTI89 outer membrane protein YejO YP_541467.1 2427033 R 364106 CDS YP_541468.1 91211482 3990403 complement(2427267..2427524) 1 NC_007946.1 hypothetical protein 2427524 3990403 UTI89_C2470 Escherichia coli UTI89 hypothetical protein YP_541468.1 2427267 R 364106 CDS YP_541469.1 91211483 3992293 2427526..2428203 1 NC_007946.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2428203 narP 3992293 narP Escherichia coli UTI89 transcriptional regulator NarP YP_541469.1 2427526 D 364106 CDS YP_541470.1 91211484 3992294 complement(2428238..2429290) 1 NC_007946.1 cytochrome c-type biogenesis protein CcmH 2429290 ccmH 3992294 ccmH Escherichia coli UTI89 cytochrome c-type biogenesis protein CcmH YP_541470.1 2428238 R 364106 CDS YP_541471.1 91211485 3992295 complement(2429287..2429844) 1 NC_007946.1 disulfide oxidoreductase 2429844 ccmG 3992295 ccmG Escherichia coli UTI89 disulfide oxidoreductase YP_541471.1 2429287 R 364106 CDS YP_541472.1 91211486 3992296 complement(2429841..2431784) 1 NC_007946.1 cytochrome c-type biogenesis protein CcmF 2431784 ccmF 3992296 ccmF Escherichia coli UTI89 cytochrome c-type biogenesis protein CcmF YP_541472.1 2429841 R 364106 CDS YP_541473.1 91211487 3992297 complement(2431781..2432260) 1 NC_007946.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2432260 ccmE 3992297 ccmE Escherichia coli UTI89 cytochrome c-type biogenesis protein CcmE YP_541473.1 2431781 R 364106 CDS YP_541474.1 91211488 3992298 complement(2432257..2432466) 1 NC_007946.1 heme exporter protein C 2432466 ccmD 3992298 ccmD Escherichia coli UTI89 heme exporter protein C YP_541474.1 2432257 R 364106 CDS YP_541475.1 91211489 3992299 complement(2432463..2433224) 1 NC_007946.1 heme exporter protein C 2433224 ccmC 3992299 ccmC Escherichia coli UTI89 heme exporter protein C YP_541475.1 2432463 R 364106 CDS YP_541476.1 91211490 3992300 complement(2433242..2433904) 1 NC_007946.1 heme exporter protein B 2433904 ccmB 3992300 ccmB Escherichia coli UTI89 heme exporter protein B YP_541476.1 2433242 R 364106 CDS YP_541477.1 91211491 3992301 complement(2433901..2434524) 1 NC_007946.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2434524 ccmA 3992301 ccmA Escherichia coli UTI89 cytochrome c biogenesis protein CcmA YP_541477.1 2433901 R 364106 CDS YP_541478.1 91211492 3992302 complement(2434537..2435139) 1 NC_007946.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2435139 napC 3992302 napC Escherichia coli UTI89 cytochrome c-type protein NapC YP_541478.1 2434537 R 364106 CDS YP_541479.2 162138405 3992303 complement(2435149..2435598) 1 NC_007946.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2435598 napB 3992303 napB Escherichia coli UTI89 citrate reductase cytochrome c-type subunit YP_541479.2 2435149 R 364106 CDS YP_541480.1 91211494 3992304 complement(2435595..2436458) 1 NC_007946.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2436458 napH 3992304 napH Escherichia coli UTI89 quinol dehydrogenase membrane component YP_541480.1 2435595 R 364106 CDS YP_541481.1 91211495 3992305 complement(2436445..2437140) 1 NC_007946.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2437140 napG 3992305 napG Escherichia coli UTI89 quinol dehydrogenase periplasmic component YP_541481.1 2436445 R 364106 CDS YP_541482.1 91211496 3992306 complement(2437147..2439633) 1 NC_007946.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2439633 napA 3992306 napA Escherichia coli UTI89 nitrate reductase catalytic subunit YP_541482.1 2437147 R 364106 CDS YP_541483.1 91211497 3992307 complement(2439630..2439893) 1 NC_007946.1 assembly protein for periplasmic nitrate reductase 2439893 napD 3992307 napD Escherichia coli UTI89 assembly protein for periplasmic nitrate reductase YP_541483.1 2439630 R 364106 CDS YP_541484.1 91211498 3992308 complement(2439883..2440377) 1 NC_007946.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein 2440377 napF 3992308 napF Escherichia coli UTI89 ferredoxin-type protein YP_541484.1 2439883 R 364106 CDS YP_541485.1 91211499 3992309 2440477..2440650 1 NC_007946.1 hypothetical protein 2440650 3992309 UTI89_C2487 Escherichia coli UTI89 hypothetical protein YP_541485.1 2440477 D 364106 CDS YP_541486.1 91211500 3992310 complement(2440570..2440698) 1 NC_007946.1 hypothetical protein 2440698 3992310 UTI89_C2488 Escherichia coli UTI89 hypothetical protein YP_541486.1 2440570 R 364106 CDS YP_541487.1 91211501 3992311 2440764..2441273 1 NC_007946.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2441273 eco 3992311 eco Escherichia coli UTI89 ecotin YP_541487.1 2440764 D 364106 CDS YP_541488.1 91211502 3992312 complement(2441423..2443069) 1 NC_007946.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2443069 mqo 3992312 mqo Escherichia coli UTI89 malate:quinone oxidoreductase YP_541488.1 2441423 R 364106 CDS YP_541489.1 91211503 3992274 complement(2443287..2444930) 1 NC_007946.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding protein 2444930 yojI 3992274 yojI Escherichia coli UTI89 multidrug transporter membrane component/ATP-binding protein YP_541489.1 2443287 R 364106 CDS YP_541490.1 91211504 3992275 complement(2445006..2445656) 1 NC_007946.1 AlkB repair system protein for alkylated DNA and RNA 2445656 alkB 3992275 alkB Escherichia coli UTI89 AlkB repair system protein for alkylated DNA and RNA YP_541490.1 2445006 R 364106 CDS YP_541491.1 91211505 3992276 complement(2445656..2446720) 1 NC_007946.1 Ada transcriptional dual regulator / O-6-methylguanine-DNA methyltransferase 2446720 ada 3992276 ada Escherichia coli UTI89 Ada transcriptional dual regulator / O-6-methylguanine-DNA methyltransferase YP_541491.1 2445656 R 364106 CDS YP_541492.1 91211506 3992277 2446454..2446672 1 NC_007946.1 hypothetical protein 2446672 3992277 UTI89_C2494 Escherichia coli UTI89 hypothetical protein YP_541492.1 2446454 D 364106 CDS YP_541493.1 91211507 3992278 complement(2446794..2447849) 1 NC_007946.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2447849 apbE 3992278 apbE Escherichia coli UTI89 thiamine biosynthesis lipoprotein ApbE YP_541493.1 2446794 R 364106 CDS YP_541494.1 91211508 3992279 2447901..2448959 1 NC_007946.1 hypothetical protein 2448959 3992279 UTI89_C2496 Escherichia coli UTI89 hypothetical protein YP_541494.1 2447901 D 364106 CDS YP_541495.1 91211509 3992280 complement(2447961..2449052) 1 NC_007946.1 allows for ions and hydrophilic solutes to cross the outer membrane; porin 2449052 ompC 3992280 ompC Escherichia coli UTI89 porin YP_541495.1 2447961 R 364106 CDS YP_541496.1 91211510 3992281 2449791..2452463 1 NC_007946.1 phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2452463 yojN 3992281 yojN Escherichia coli UTI89 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_541496.1 2449791 D 364106 CDS YP_541497.1 91211511 3992282 2452435..2453130 1 NC_007946.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2453130 rcsB 3992282 rcsB Escherichia coli UTI89 transcriptional regulator RcsB YP_541497.1 2452435 D 364106 CDS YP_541498.1 91211512 3992283 complement(2453330..2456179) 1 NC_007946.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2456179 rcsC 3992283 rcsC Escherichia coli UTI89 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_541498.1 2453330 R 364106 CDS YP_541499.1 91211513 3992284 2456334..2458172 1 NC_007946.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2458172 atoS 3992284 atoS Escherichia coli UTI89 sensory histidine kinase AtoS YP_541499.1 2456334 D 364106 CDS YP_541500.1 91211514 3992285 2458169..2459554 1 NC_007946.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2459554 atoC 3992285 atoC Escherichia coli UTI89 acetoacetate metabolism regulatory protein AtoC YP_541500.1 2458169 D 364106 CDS YP_541501.1 91211515 3992286 2459750..2460412 1 NC_007946.1 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2460412 atoD 3992286 atoD Escherichia coli UTI89 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_541501.1 2459750 D 364106 CDS YP_541502.1 91211516 3992287 2460412..2461062 1 NC_007946.1 acetate CoA-transferase subunit beta 2461062 atoA 3992287 atoA Escherichia coli UTI89 acetate CoA-transferase subunit beta YP_541502.1 2460412 D 364106 CDS YP_541503.1 91211517 3992288 2461059..2462381 1 NC_007946.1 short-chain fatty acids transporter 2462381 atoE 3992288 atoE Escherichia coli UTI89 short-chain fatty acids transporter YP_541503.1 2461059 D 364106 CDS YP_541504.1 91211518 3992289 2462412..2463596 1 NC_007946.1 acetyl-CoA acetyltransferase 2463596 atoB 3992289 atoB Escherichia coli UTI89 acetyl-CoA acetyltransferase YP_541504.1 2462412 D 364106 CDS YP_541505.1 91211519 3992290 complement(2463670..2464446) 1 NC_007946.1 hypothetical protein 2464446 yfaP 3992290 yfaP Escherichia coli UTI89 hypothetical protein YP_541505.1 2463670 R 364106 CDS YP_541506.1 91211520 3992291 complement(2464451..2466100) 1 NC_007946.1 hypothetical protein 2466100 yfaQ 3992291 yfaQ Escherichia coli UTI89 hypothetical protein YP_541506.1 2464451 R 364106 CDS YP_541507.1 91211521 3992292 complement(2466101..2470630) 1 NC_007946.1 hypothetical protein 2470630 3992292 UTI89_C2509 Escherichia coli UTI89 hypothetical protein YP_541507.1 2466101 R 364106 CDS YP_541508.1 91211522 3992352 complement(2470639..2471289) 1 NC_007946.1 hypothetical protein 2471289 yfaT 3992352 yfaT Escherichia coli UTI89 hypothetical protein YP_541508.1 2470639 R 364106 CDS YP_541509.2 162138404 3992353 complement(2471259..2472947) 1 NC_007946.1 hypothetical protein 2472947 yfaA 3992353 yfaA Escherichia coli UTI89 hypothetical protein YP_541509.2 2471259 R 364106 CDS YP_541510.1 91211524 3992354 complement(2473096..2475723) 1 NC_007946.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2475723 gyrA 3992354 gyrA Escherichia coli UTI89 DNA gyrase subunit A YP_541510.1 2473096 R 364106 CDS YP_541511.1 91211525 3992355 2475870..2476592 1 NC_007946.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2476592 ubiG 3992355 ubiG Escherichia coli UTI89 3-demethylubiquinone-9 3-methyltransferase YP_541511.1 2475870 D 364106 CDS YP_541512.1 91211526 3992356 complement(2476732..2480496) 1 NC_007946.1 adhesin 2480496 yfaL 3992356 yfaL Escherichia coli UTI89 adhesin YP_541512.1 2476732 R 364106 CDS YP_541513.1 91211527 3992357 2481172..2483457 1 NC_007946.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2483457 nrdA 3992357 nrdA Escherichia coli UTI89 ribonucleotide-diphosphate reductase subunit alpha YP_541513.1 2481172 D 364106 CDS YP_541514.1 91211528 3992358 2483604..2484734 1 NC_007946.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2484734 nrdB 3992358 nrdB Escherichia coli UTI89 ribonucleotide-diphosphate reductase subunit beta YP_541514.1 2483604 D 364106 CDS YP_541515.1 91211529 3992359 2484734..2484988 1 NC_007946.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2484988 yfaE 3992359 yfaE Escherichia coli UTI89 2Fe-2S ferredoxin YP_541515.1 2484734 D 364106 CDS YP_541516.1 91211530 3992360 complement(2485042..2485692) 1 NC_007946.1 hypothetical protein 2485692 inaA 3992360 inaA Escherichia coli UTI89 hypothetical protein YP_541516.1 2485042 R 364106 CDS YP_541517.1 91211531 3992361 complement(2485895..2486971) 1 NC_007946.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2486971 glpQ 3992361 glpQ Escherichia coli UTI89 glycerophosphodiester phosphodiesterase YP_541517.1 2485895 R 364106 CDS YP_541518.1 91211532 3992362 complement(2486976..2488334) 1 NC_007946.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2488334 glpT 3992362 glpT Escherichia coli UTI89 sn-glycerol-3-phosphate transporter YP_541518.1 2486976 R 364106 CDS YP_541519.1 91211533 3992363 2488607..2490235 1 NC_007946.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2490235 glpA 3992363 glpA Escherichia coli UTI89 sn-glycerol-3-phosphate dehydrogenase subunit A YP_541519.1 2488607 D 364106 CDS YP_541520.1 91211534 3992364 2490153..2491484 1 NC_007946.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2491484 glpB 3992364 glpB Escherichia coli UTI89 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_541520.1 2490153 D 364106 CDS YP_541521.2 162138403 3992365 2491481..2492671 1 NC_007946.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2492671 glpC 3992365 glpC Escherichia coli UTI89 sn-glycerol-3-phosphate dehydrogenase subunit C YP_541521.2 2491481 D 364106 CDS YP_541522.1 91211536 3992366 2492696..2492821 1 NC_007946.1 hypothetical protein 2492821 3992366 UTI89_C2524 Escherichia coli UTI89 hypothetical protein YP_541522.1 2492696 D 364106 CDS YP_541523.1 91211537 3992367 2492864..2493823 1 NC_007946.1 hypothetical protein 2493823 yfaD 3992367 yfaD Escherichia coli UTI89 hypothetical protein YP_541523.1 2492864 D 364106 CDS YP_541524.1 91211538 3992368 2493836..2494021 1 NC_007946.1 hypothetical protein 2494021 3992368 UTI89_C2526 Escherichia coli UTI89 hypothetical protein YP_541524.1 2493836 D 364106 CDS YP_541525.1 91211539 3992369 complement(2494062..2494865) 1 NC_007946.1 aldolase 2494865 yfaU 3992369 yfaU Escherichia coli UTI89 aldolase YP_541525.1 2494062 R 364106 CDS YP_541526.1 91211540 3992370 complement(2494883..2496211) 1 NC_007946.1 transport protein YfaV 2496211 yfaV 3992370 yfaV Escherichia coli UTI89 transport protein YfaV YP_541526.1 2494883 R 364106 CDS YP_541527.1 91211541 3992371 complement(2496229..2497446) 1 NC_007946.1 hypothetical protein 2497446 yfaW 3992371 yfaW Escherichia coli UTI89 hypothetical protein YP_541527.1 2496229 R 364106 CDS YP_541528.1 91211542 3990977 complement(2497449..2498231) 1 NC_007946.1 transcriptional regulator YfaX 2498231 yfaX 3990977 yfaX Escherichia coli UTI89 transcriptional regulator YfaX YP_541528.1 2497449 R 364106 CDS YP_541529.1 91211543 3990978 complement(2498451..2499653) 1 NC_007946.1 competence damage-inducible protein A 2499653 3990978 UTI89_C2531 Escherichia coli UTI89 competence damage-inducible protein A YP_541529.1 2498451 R 364106 CDS YP_541530.1 91211544 3990979 complement(2499753..2500316) 1 NC_007946.1 hypothetical protein 2500316 yfaZ 3990979 yfaZ Escherichia coli UTI89 hypothetical protein YP_541530.1 2499753 R 364106 CDS YP_541531.1 91211545 3990980 2500574..2500999 1 NC_007946.1 Nudix hydrolase YfaO 2500999 yfaO 3990980 yfaO Escherichia coli UTI89 Nudix hydrolase YfaO YP_541531.1 2500574 D 364106 CDS YP_541532.1 91211546 3990981 complement(2501038..2501667) 1 NC_007946.1 Ais protein 2501667 ais 3990981 ais Escherichia coli UTI89 Ais protein YP_541532.1 2501038 R 364106 CDS YP_541533.2 162138402 3990982 2501948..2503087 1 NC_007946.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2503087 yfbE 3990982 yfbE Escherichia coli UTI89 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_541533.2 2501948 D 364106 CDS YP_541534.1 91211548 3990983 2503091..2504059 1 NC_007946.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2504059 3990983 UTI89_C2536 Escherichia coli UTI89 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_541534.1 2503091 D 364106 CDS YP_541535.1 91211549 3990984 2504059..2506041 1 NC_007946.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2506041 yfbG 3990984 yfbG Escherichia coli UTI89 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_541535.1 2504059 D 364106 CDS YP_541536.1 91211550 3990985 2506038..2506928 1 NC_007946.1 hypothetical protein 2506928 yfbH 3990985 yfbH Escherichia coli UTI89 hypothetical protein YP_541536.1 2506038 D 364106 CDS YP_541537.1 91211551 3990986 2506928..2508580 1 NC_007946.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2508580 arnT 3990986 arnT Escherichia coli UTI89 4-amino-4-deoxy-L-arabinose transferase YP_541537.1 2506928 D 364106 CDS YP_541538.1 91211552 3990987 2508577..2508912 1 NC_007946.1 hypothetical protein 2508912 3990987 UTI89_C2540 Escherichia coli UTI89 hypothetical protein YP_541538.1 2508577 D 364106 CDS YP_541539.1 91211553 3990988 2508630..2509298 1 NC_007946.1 hypothetical protein 2509298 yfbJ 3990988 yfbJ Escherichia coli UTI89 hypothetical protein YP_541539.1 2508630 D 364106 CDS YP_541540.1 91211554 3990989 complement(2509292..2509588) 1 NC_007946.1 polymyxin B resistance protein PmrD 2509588 pmrD 3990989 pmrD Escherichia coli UTI89 polymyxin B resistance protein PmrD YP_541540.1 2509292 R 364106 CDS YP_541541.1 91211555 3990990 complement(2509668..2511023) 1 NC_007946.1 O-succinylbenzoic acid--CoA ligase 2511023 menE 3990990 menE Escherichia coli UTI89 O-succinylbenzoic acid--CoA ligase YP_541541.1 2509668 R 364106 CDS YP_541542.1 91211556 3990991 complement(2511020..2511982) 1 NC_007946.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2511982 menC 3990991 menC Escherichia coli UTI89 O-succinylbenzoate synthase YP_541542.1 2511020 R 364106 CDS YP_541543.1 91211557 3990992 complement(2511982..2512839) 1 NC_007946.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2512839 menB 3990992 menB Escherichia coli UTI89 naphthoate synthase YP_541543.1 2511982 R 364106 CDS YP_541544.1 91211558 3990993 2512171..2513004 1 NC_007946.1 hypothetical protein 2513004 3990993 UTI89_C2546 Escherichia coli UTI89 hypothetical protein YP_541544.1 2512171 D 364106 CDS YP_541545.1 91211559 3990994 complement(2512854..2513612) 1 NC_007946.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 2513612 yfbB 3990994 yfbB Escherichia coli UTI89 acyl-CoA thioester hydrolase YP_541545.1 2512854 R 364106 CDS YP_541546.1 91211560 3990995 complement(2513609..2515468) 1 NC_007946.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2515468 menD 3990995 menD Escherichia coli UTI89 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_541546.1 2513609 R 364106 CDS YP_541547.1 91211561 3991758 complement(2515368..2516663) 1 NC_007946.1 menaquinone-specific isochorismate synthase 2516663 menF 3991758 menF Escherichia coli UTI89 menaquinone-specific isochorismate synthase YP_541547.1 2515368 R 364106 CDS YP_541548.1 91211562 3991759 complement(2516742..2517047) 1 NC_007946.1 hypothetical protein 2517047 elaB 3991759 elaB Escherichia coli UTI89 hypothetical protein YP_541548.1 2516742 R 364106 CDS YP_541549.1 91211563 3991760 complement(2517102..2517563) 1 NC_007946.1 hypothetical protein 2517563 elaA 3991760 elaA Escherichia coli UTI89 hypothetical protein YP_541549.1 2517102 R 364106 CDS YP_541550.1 91211564 3991761 2517628..2518545 1 NC_007946.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2518545 elaC 3991761 elaC Escherichia coli UTI89 ribonuclease Z YP_541550.1 2517628 D 364106 CDS YP_541551.1 91211565 3991762 complement(2518666..2520408) 1 NC_007946.1 hypothetical protein 2520408 yfbK 3991762 yfbK Escherichia coli UTI89 hypothetical protein YP_541551.1 2518666 R 364106 CDS YP_541552.1 91211566 3991763 2520540..2521517 1 NC_007946.1 aminopeptidase 2521517 yfbL 3991763 yfbL Escherichia coli UTI89 aminopeptidase YP_541552.1 2520540 D 364106 CDS YP_541553.1 91211567 3991764 2521620..2522123 1 NC_007946.1 hypothetical protein 2522123 yfbM 3991764 yfbM Escherichia coli UTI89 hypothetical protein YP_541553.1 2521620 D 364106 CDS YP_541554.1 91211568 3991765 complement(2522190..2523647) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2523647 nuoN 3991765 nuoN Escherichia coli UTI89 NADH dehydrogenase subunit N YP_541554.1 2522190 R 364106 CDS YP_541555.1 91211569 3991766 complement(2523654..2525183) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2525183 nuoM 3991766 nuoM Escherichia coli UTI89 NADH dehydrogenase subunit M YP_541555.1 2523654 R 364106 CDS YP_541556.1 91211570 3991767 complement(2525347..2527188) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2527188 nuoL 3991767 nuoL Escherichia coli UTI89 NADH dehydrogenase subunit L YP_541556.1 2525347 R 364106 CDS YP_541557.1 91211571 3991768 complement(2527185..2527487) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2527487 nuoK 3991768 nuoK Escherichia coli UTI89 NADH dehydrogenase subunit K YP_541557.1 2527185 R 364106 CDS YP_541558.1 91211572 3991769 complement(2527484..2528038) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2528038 nuoJ 3991769 nuoJ Escherichia coli UTI89 NADH dehydrogenase subunit J YP_541558.1 2527484 R 364106 CDS YP_541559.1 91211573 3991770 complement(2528050..2528592) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2528592 nuoI 3991770 nuoI Escherichia coli UTI89 NADH dehydrogenase subunit I YP_541559.1 2528050 R 364106 CDS YP_541560.1 91211574 3991771 complement(2528607..2529584) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2529584 nuoH 3991771 nuoH Escherichia coli UTI89 NADH dehydrogenase subunit H YP_541560.1 2528607 R 364106 CDS YP_541561.1 91211575 3991772 complement(2529581..2532313) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2532313 nuoG 3991772 nuoG Escherichia coli UTI89 NADH dehydrogenase subunit G YP_541561.1 2529581 R 364106 CDS YP_541562.1 91211576 3991773 complement(2532360..2533697) 1 NC_007946.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2533697 nuoF 3991773 nuoF Escherichia coli UTI89 NADH dehydrogenase I subunit F YP_541562.1 2532360 R 364106 CDS YP_541563.1 91211577 3991774 complement(2533694..2534194) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2534194 nuoE 3991774 nuoE Escherichia coli UTI89 NADH dehydrogenase subunit E YP_541563.1 2533694 R 364106 CDS YP_541564.1 91211578 3991775 complement(2534197..2535999) 1 NC_007946.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2535999 nuoC 3991775 nuoC Escherichia coli UTI89 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_541564.1 2534197 R 364106 CDS YP_541565.1 91211579 3991776 complement(2536093..2536755) 1 NC_007946.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2536755 3991776 UTI89_C2567 Escherichia coli UTI89 NADH dehydrogenase subunit B YP_541565.1 2536093 R 364106 CDS YP_541566.1 91211580 3991777 complement(2536771..2537214) 1 NC_007946.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2537214 nuoA 3991777 nuoA Escherichia coli UTI89 NADH dehydrogenase subunit A YP_541566.1 2536771 R 364106 CDS YP_541567.1 91211581 3993214 complement(2537361..2537630) 1 NC_007946.1 hypothetical protein 2537630 3993214 UTI89_C2569 Escherichia coli UTI89 hypothetical protein YP_541567.1 2537361 R 364106 CDS YP_541568.1 91211582 3993215 complement(2537844..2538782) 1 NC_007946.1 transcriptional regulator LrhA 2538782 lrhA 3993215 lrhA Escherichia coli UTI89 transcriptional regulator LrhA YP_541568.1 2537844 R 364106 CDS YP_541569.1 91211583 3993216 2539022..2539276 1 NC_007946.1 hypothetical protein 2539276 3993216 UTI89_C2571 Escherichia coli UTI89 hypothetical protein YP_541569.1 2539022 D 364106 CDS YP_541570.1 91211584 3993217 2539702..2540919 1 NC_007946.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2540919 3993217 UTI89_C2572 Escherichia coli UTI89 aminotransferase YP_541570.1 2539702 D 364106 CDS YP_541571.1 91211585 3993218 2541003..2541602 1 NC_007946.1 hypothetical protein 2541602 yfbR 3993218 yfbR Escherichia coli UTI89 hypothetical protein YP_541571.1 2541003 D 364106 CDS YP_541572.1 91211586 3993219 complement(2541661..2543493) 1 NC_007946.1 transport protein 2543493 yfbS 3993219 yfbS Escherichia coli UTI89 transport protein YP_541572.1 2541661 R 364106 CDS YP_541573.1 91211587 3993220 complement(2543580..2544230) 1 NC_007946.1 phosphatase 2544230 yfbT 3993220 yfbT Escherichia coli UTI89 phosphatase YP_541573.1 2543580 R 364106 CDS YP_541574.1 91211588 3993221 complement(2544241..2544753) 1 NC_007946.1 hypothetical protein 2544753 3993221 UTI89_C2576 Escherichia coli UTI89 hypothetical protein YP_541574.1 2544241 R 364106 CDS YP_541575.1 91211589 3993222 complement(2544818..2545273) 1 NC_007946.1 hypothetical protein 2545273 yfbV 3993222 yfbV Escherichia coli UTI89 hypothetical protein YP_541575.1 2544818 R 364106 CDS YP_541576.1 91211590 3993223 complement(2545342..2545473) 1 NC_007946.1 hypothetical protein 2545473 3993223 UTI89_C2578 Escherichia coli UTI89 hypothetical protein YP_541576.1 2545342 R 364106 CDS YP_541577.1 91211591 3993224 2545611..2546813 1 NC_007946.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2546813 3993224 UTI89_C2579 Escherichia coli UTI89 acetate kinase YP_541577.1 2545611 D 364106 CDS YP_541578.1 91211592 3993225 complement(2546816..2549086) 1 NC_007946.1 hypothetical protein 2549086 3993225 UTI89_C2580 Escherichia coli UTI89 hypothetical protein YP_541578.1 2546816 R 364106 CDS YP_541579.1 91211593 3993226 2546888..2549032 1 NC_007946.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2549032 pta 3993226 pta Escherichia coli UTI89 phosphate acetyltransferase YP_541579.1 2546888 D 364106 CDS YP_541580.2 162138401 3993227 2549222..2550742 1 NC_007946.1 hypothetical protein 2550742 yfcC 3993227 yfcC Escherichia coli UTI89 hypothetical protein YP_541580.2 2549222 D 364106 CDS YP_541581.1 91211595 3993228 complement(2550775..2551317) 1 NC_007946.1 regulator 2551317 3993228 UTI89_C2583 Escherichia coli UTI89 regulator YP_541581.1 2550775 R 364106 CDS YP_541582.1 91211596 3993229 complement(2551375..2551929) 1 NC_007946.1 phosphodiesterase 2551929 yfcE 3993229 yfcE Escherichia coli UTI89 phosphodiesterase YP_541582.1 2551375 R 364106 CDS YP_541583.1 91211597 3993230 complement(2551982..2552626) 1 NC_007946.1 hypothetical protein 2552626 yfcF 3993230 yfcF Escherichia coli UTI89 hypothetical protein YP_541583.1 2551982 R 364106 CDS YP_541584.1 91211598 3993231 2552762..2553409 1 NC_007946.1 glutathione S-transferase 2553409 yfcG 3993231 yfcG Escherichia coli UTI89 glutathione S-transferase YP_541584.1 2552762 D 364106 CDS YP_541585.1 91211599 3993232 2553466..2553828 1 NC_007946.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2553828 folX 3993232 folX Escherichia coli UTI89 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_541585.1 2553466 D 364106 CDS YP_541586.1 91211600 3992716 2553849..2554742 1 NC_007946.1 sugar nucleotide epimerase 2554742 yfcH 3992716 yfcH Escherichia coli UTI89 sugar nucleotide epimerase YP_541586.1 2553849 D 364106 CDS YP_541587.1 91211601 3992717 complement(2554790..2555680) 1 NC_007946.1 hypothetical protein 2555680 yfcI 3992717 yfcI Escherichia coli UTI89 hypothetical protein YP_541587.1 2554790 R 364106 CDS YP_541588.1 91211602 3992718 complement(2555876..2556649) 1 NC_007946.1 histidine/lysine/arginine/ornithine transporter subunit 2556649 hisP 3992718 hisP Escherichia coli UTI89 histidine/lysine/arginine/ornithine transporter subunit YP_541588.1 2555876 R 364106 CDS YP_541589.1 91211603 3992719 complement(2556657..2557373) 1 NC_007946.1 histidine transport system membrane protein M 2557373 hisM 3992719 hisM Escherichia coli UTI89 histidine transport system membrane protein M YP_541589.1 2556657 R 364106 CDS YP_541590.1 91211604 3992720 complement(2557370..2558056) 1 NC_007946.1 histidine transport system permease hisQ 2558056 hisQ 3992720 hisQ Escherichia coli UTI89 histidine transport system permease hisQ YP_541590.1 2557370 R 364106 CDS YP_541591.1 91211605 3992721 complement(2558146..2558928) 1 NC_007946.1 histidine-binding periplasmic protein of high-affinity histidine transport system 2558928 hisJ 3992721 hisJ Escherichia coli UTI89 histidine-binding periplasmic protein of high-affinity histidine transport system YP_541591.1 2558146 R 364106 CDS YP_541592.1 91211606 3992722 complement(2559149..2559931) 1 NC_007946.1 lysine-arginine-ornithine-binding periplasmic protein 2559931 argT 3992722 argT Escherichia coli UTI89 lysine-arginine-ornithine-binding periplasmic protein YP_541592.1 2559149 R 364106 CDS YP_541593.1 91211607 3992723 complement(2560197..2560766) 1 NC_007946.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2560766 ubiX 3992723 ubiX Escherichia coli UTI89 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_541593.1 2560197 R 364106 CDS YP_541594.1 91211608 3992724 complement(2560861..2562378) 1 NC_007946.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2562378 purF 3992724 purF Escherichia coli UTI89 amidophosphoribosyltransferase YP_541594.1 2560861 R 364106 CDS YP_541595.1 91211609 3992725 complement(2562415..2562903) 1 NC_007946.1 membrane protein required for colicin V production; colicin V production protein 2562903 cvpA 3992725 cvpA Escherichia coli UTI89 colicin V production protein YP_541595.1 2562415 R 364106 CDS YP_541596.1 91211610 3992726 2563005..2563175 1 NC_007946.1 hypothetical protein 2563175 3992726 UTI89_C2598 Escherichia coli UTI89 hypothetical protein YP_541596.1 2563005 D 364106 CDS YP_541597.2 162138400 3992727 complement(2563435..2564097) 1 NC_007946.1 hypothetical protein 2564097 dedD 3992727 dedD Escherichia coli UTI89 hypothetical protein YP_541597.2 2563435 R 364106 CDS YP_541598.1 91211612 3992728 complement(2564087..2565355) 1 NC_007946.1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2565355 folC 3992728 folC Escherichia coli UTI89 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_541598.1 2564087 R 364106 CDS YP_541599.2 162138399 3992729 complement(2565425..2566339) 1 NC_007946.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2566339 accD 3992729 accD Escherichia coli UTI89 acetyl-CoA carboxylase subunit beta YP_541599.2 2565425 R 364106 CDS YP_541600.1 91211614 3992730 complement(2566495..2567154) 1 NC_007946.1 hypothetical protein 2567154 dedA 3992730 dedA Escherichia coli UTI89 hypothetical protein YP_541600.1 2566495 R 364106 CDS YP_541601.1 91211615 3992731 complement(2567237..2568049) 1 NC_007946.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2568049 truA 3992731 truA Escherichia coli UTI89 tRNA pseudouridine synthase A YP_541601.1 2567237 R 364106 CDS YP_541602.1 91211616 3992732 complement(2568049..2569062) 1 NC_007946.1 semialdehyde dehydrogenase 2569062 usg 3992732 usg Escherichia coli UTI89 semialdehyde dehydrogenase YP_541602.1 2568049 R 364106 CDS YP_541603.1 91211617 3992733 complement(2569128..2570264) 1 NC_007946.1 erythronate-4-phosphate dehydrogenase 2570264 pdxB 3992733 pdxB Escherichia coli UTI89 erythronate-4-phosphate dehydrogenase YP_541603.1 2569128 R 364106 CDS YP_541604.1 91211618 3992734 2570363..2571358 1 NC_007946.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2571358 flk 3992734 flk Escherichia coli UTI89 flagella biosynthesis regulator YP_541604.1 2570363 D 364106 CDS YP_541605.1 91211619 3992735 complement(2571355..2572533) 1 NC_007946.1 hypothetical protein 2572533 yfcJ 3992735 yfcJ Escherichia coli UTI89 hypothetical protein YP_541605.1 2571355 R 364106 CDS YP_541606.1 91211620 3991778 complement(2572798..2574018) 1 NC_007946.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2574018 fabB 3991778 fabB Escherichia coli UTI89 3-oxoacyl-ACP synthase YP_541606.1 2572798 R 364106 CDS YP_541607.2 162138398 3991779 2574177..2576183 1 NC_007946.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2576183 mnmC 3991779 mnmC Escherichia coli UTI89 5-methylaminomethyl-2-thiouridine methyltransferase YP_541607.2 2574177 D 364106 CDS YP_541608.1 91211622 3991780 complement(2576304..2576582) 1 NC_007946.1 hypothetical protein 2576582 yfcL 3991780 yfcL Escherichia coli UTI89 hypothetical protein YP_541608.1 2576304 R 364106 CDS YP_541609.1 91211623 3991781 complement(2576616..2577164) 1 NC_007946.1 hypothetical protein 2577164 yfcM 3991781 yfcM Escherichia coli UTI89 hypothetical protein YP_541609.1 2576616 R 364106 CDS YP_541610.1 91211624 3991782 complement(2577164..2577973) 1 NC_007946.1 hypothetical protein 2577973 yfcA 3991782 yfcA Escherichia coli UTI89 hypothetical protein YP_541610.1 2577164 R 364106 CDS YP_541611.1 91211625 3991783 complement(2577973..2578797) 1 NC_007946.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2578797 mepA 3991783 mepA Escherichia coli UTI89 penicillin-insensitive murein endopeptidase YP_541611.1 2577973 R 364106 CDS YP_541612.1 91211626 3991784 complement(2578801..2579889) 1 NC_007946.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2579889 aroC 3991784 aroC Escherichia coli UTI89 chorismate synthase YP_541612.1 2578801 R 364106 CDS YP_541613.1 91211627 3991785 complement(2579921..2581186) 1 NC_007946.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2581186 prmB 3991785 prmB Escherichia coli UTI89 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_541613.1 2579921 R 364106 CDS YP_541614.1 91211628 3991786 2581019..2581570 1 NC_007946.1 hypothetical protein 2581570 yfcN 3991786 yfcN Escherichia coli UTI89 hypothetical protein YP_541614.1 2581019 D 364106 CDS YP_541615.1 91211629 3991787 complement(2581890..2582747) 1 NC_007946.1 fimbrial adhesin YfcO 2582747 yfcO 3991787 yfcO Escherichia coli UTI89 fimbrial adhesin YfcO YP_541615.1 2581890 R 364106 CDS YP_541616.1 91211630 3991788 complement(2582734..2583261) 1 NC_007946.1 Yfc fimbriae subunit YfcP 2583261 yfcP 3991788 yfcP Escherichia coli UTI89 Yfc fimbriae subunit YfcP YP_541616.1 2582734 R 364106 CDS YP_541617.1 91211631 3991789 complement(2583258..2583737) 1 NC_007946.1 Yfc fimbriae subunit YfcQ 2583737 yfcQ 3991789 yfcQ Escherichia coli UTI89 Yfc fimbriae subunit YfcQ YP_541617.1 2583258 R 364106 CDS YP_541618.1 91211632 3991790 complement(2583734..2584237) 1 NC_007946.1 Yfc fimbriae subunit YfcR 2584237 yfcR 3991790 yfcR Escherichia coli UTI89 Yfc fimbriae subunit YfcR YP_541618.1 2583734 R 364106 CDS YP_541619.1 91211633 3991791 complement(2584254..2585006) 1 NC_007946.1 periplasmic chaperone YfcS 2585006 yfcS 3991791 yfcS Escherichia coli UTI89 periplasmic chaperone YfcS YP_541619.1 2584254 R 364106 CDS YP_541620.1 91211634 3991792 complement(2585026..2587680) 1 NC_007946.1 outer membrane usher YfcU 2587680 yfcU 3991792 yfcU Escherichia coli UTI89 outer membrane usher YfcU YP_541620.1 2585026 R 364106 CDS YP_541621.1 91211635 3991793 complement(2587548..2588297) 1 NC_007946.1 Yfc fimbriae subunit YfcV 2588297 yfcV 3991793 yfcV Escherichia coli UTI89 Yfc fimbriae subunit YfcV YP_541621.1 2587548 R 364106 CDS YP_541622.1 91211636 3991794 complement(2588863..2589348) 1 NC_007946.1 phosphohistidine phosphatase 2589348 3991794 UTI89_C2624 Escherichia coli UTI89 phosphohistidine phosphatase YP_541622.1 2588863 R 364106 CDS YP_541623.1 91211637 3991795 complement(2589551..2591695) 1 NC_007946.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2591695 fadJ 3991795 fadJ Escherichia coli UTI89 multifunctional fatty acid oxidation complex subunit alpha YP_541623.1 2589551 R 364106 CDS YP_541624.1 91211638 3991796 complement(2591695..2593005) 1 NC_007946.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2593005 fadI 3991796 fadI Escherichia coli UTI89 3-ketoacyl-CoA thiolase YP_541624.1 2591695 R 364106 CDS YP_541625.1 91211639 3991797 complement(2593186..2593494) 1 NC_007946.1 hypothetical protein 2593494 yfcZ 3991797 yfcZ Escherichia coli UTI89 hypothetical protein YP_541625.1 2593186 R 364106 CDS YP_541626.1 91211640 3991798 complement(2593555..2593806) 1 NC_007946.1 hypothetical protein 2593806 3991798 UTI89_C2628 Escherichia coli UTI89 hypothetical protein YP_541626.1 2593555 R 364106 CDS YP_541627.1 91211641 3991799 2593836..2595182 1 NC_007946.1 sensitivity to phage T2; long-chain fatty acid outer membrane transporter 2595182 fadL 3991799 fadL Escherichia coli UTI89 long-chain fatty acid outer membrane transporter YP_541627.1 2593836 D 364106 CDS YP_541628.1 91211642 3991800 complement(2595240..2595995) 1 NC_007946.1 VacJ lipoprotein 2595995 vacJ 3991800 vacJ Escherichia coli UTI89 VacJ lipoprotein YP_541628.1 2595240 R 364106 CDS YP_541629.1 91211643 3991801 complement(2596021..2596191) 1 NC_007946.1 hypothetical protein 2596191 3991801 UTI89_C2631 Escherichia coli UTI89 hypothetical protein YP_541629.1 2596021 R 364106 CDS YP_541630.1 91211644 3991802 2596289..2597221 1 NC_007946.1 transport 2597221 yfdC 3991802 yfdC Escherichia coli UTI89 transport YP_541630.1 2596289 D 364106 CDS YP_541631.1 91211645 3991804 2597497..2598690 1 NC_007946.1 prophage integrase 2598690 intC 3991804 intC Escherichia coli UTI89 prophage integrase YP_541631.1 2597497 D 364106 CDS YP_541632.1 91211646 3991805 complement(2598930..2599265) 1 NC_007946.1 hypothetical protein 2599265 3991805 UTI89_C2635 Escherichia coli UTI89 hypothetical protein YP_541632.1 2598930 R 364106 CDS YP_541633.1 91211647 3991806 complement(2599874..2602819) 1 NC_007946.1 endo-alpha-sialidase 2602819 sia 3991806 sia Escherichia coli UTI89 endo-alpha-sialidase YP_541633.1 2599874 R 364106 CDS YP_541634.1 91211648 3991807 complement(2602920..2603843) 1 NC_007946.1 antirepressor protein 2603843 ant 3991807 ant Escherichia coli UTI89 antirepressor protein YP_541634.1 2602920 R 364106 CDS YP_541635.1 91211649 3991808 2604353..2604610 1 NC_007946.1 hypothetical protein 2604610 3991808 UTI89_C2638 Escherichia coli UTI89 hypothetical protein YP_541635.1 2604353 D 364106 CDS YP_541636.1 91211650 3991809 2604634..2604882 1 NC_007946.1 regulatory protein 2604882 mnt 3991809 mnt Escherichia coli UTI89 regulatory protein YP_541636.1 2604634 D 364106 CDS YP_541637.1 91211651 3991810 2604925..2605524 1 NC_007946.1 hypothetical protein 2605524 3991810 UTI89_C2640 Escherichia coli UTI89 hypothetical protein YP_541637.1 2604925 D 364106 CDS YP_541638.1 91211652 3991811 2605509..2605928 1 NC_007946.1 hypothetical protein 2605928 3991811 UTI89_C2641 Escherichia coli UTI89 hypothetical protein YP_541638.1 2605509 D 364106 CDS YP_541639.1 91211653 3991812 2605951..2606274 1 NC_007946.1 hypothetical protein 2606274 hkcB 3991812 hkcB Escherichia coli UTI89 hypothetical protein YP_541639.1 2605951 D 364106 CDS YP_541640.1 91211654 3991813 complement(2606275..2608434) 1 NC_007946.1 bacteriophage HK620 gene 16-like; DNA transfer protein 2608434 3991813 UTI89_C2643 Escherichia coli UTI89 DNA transfer protein YP_541640.1 2606275 R 364106 CDS YP_541641.1 91211655 3991814 complement(2608434..2609783) 1 NC_007946.1 bacteriophage HK620 gene 20-like; DNA transfer protein 2609783 3991814 UTI89_C2644 Escherichia coli UTI89 DNA transfer protein YP_541641.1 2608434 R 364106 CDS YP_541642.1 91211656 3991892 complement(2609794..2610486) 1 NC_007946.1 bacteriophage HK620 gene 7-like; DNA transfer protein 2610486 3991892 UTI89_C2645 Escherichia coli UTI89 DNA transfer protein YP_541642.1 2609794 R 364106 CDS YP_541643.1 91211657 3991893 complement(2610489..2610944) 1 NC_007946.1 bacteriophage HK620 gene 14-like; head assembly protein 2610944 3991893 UTI89_C2646 Escherichia coli UTI89 head assembly protein YP_541643.1 2610489 R 364106 CDS YP_541644.1 91211658 3991894 complement(2610944..2611645) 1 NC_007946.1 bacteriophage HK620 gene 26-like; DNA stabilization protein 2611645 3991894 UTI89_C2647 Escherichia coli UTI89 DNA stabilization protein YP_541644.1 2610944 R 364106 CDS YP_541645.1 91211659 3991895 complement(2611645..2613063) 1 NC_007946.1 bacteriophage HK620 gene 10-like; DNA stabilization protein 2613063 3991895 UTI89_C2648 Escherichia coli UTI89 DNA stabilization protein YP_541645.1 2611645 R 364106 CDS YP_541646.1 91211660 3991896 complement(2613073..2613534) 1 NC_007946.1 hypothetical protein 2613534 3991896 UTI89_C2649 Escherichia coli UTI89 hypothetical protein YP_541646.1 2613073 R 364106 CDS YP_541647.1 91211661 3991897 complement(2613515..2613742) 1 NC_007946.1 hypothetical protein 2613742 3991897 UTI89_C2650 Escherichia coli UTI89 hypothetical protein YP_541647.1 2613515 R 364106 CDS YP_541648.1 91211662 3991898 complement(2613745..2614998) 1 NC_007946.1 hypothetical protein 2614998 3991898 UTI89_C2651 Escherichia coli UTI89 hypothetical protein YP_541648.1 2613745 R 364106 CDS YP_541649.1 91211663 3991899 complement(2615017..2615910) 1 NC_007946.1 bacteriophage HK620 gene 8-like; scaffold protein 2615910 3991899 UTI89_C2652 Escherichia coli UTI89 scaffold protein YP_541649.1 2615017 R 364106 CDS YP_541650.1 91211664 3991900 complement(2616001..2618199) 1 NC_007946.1 bacteriophage HK620 gene 1-like; portal protein 2618199 3991900 UTI89_C2653 Escherichia coli UTI89 portal protein YP_541650.1 2616001 R 364106 CDS YP_541651.1 91211665 3991901 complement(2618201..2619616) 1 NC_007946.1 bacteriophage HK620 gene 2-like; terminase large subunit 2619616 3991901 UTI89_C2654 Escherichia coli UTI89 terminase large subunit YP_541651.1 2618201 R 364106 CDS YP_541652.1 91211666 3991902 complement(2619613..2620053) 1 NC_007946.1 hypothetical protein 2620053 3991902 UTI89_C2655 Escherichia coli UTI89 hypothetical protein YP_541652.1 2619613 R 364106 CDS YP_541653.1 91211667 3991903 complement(2620056..2620298) 1 NC_007946.1 hypothetical protein 2620298 hkbM 3991903 hkbM Escherichia coli UTI89 hypothetical protein YP_541653.1 2620056 R 364106 CDS YP_541654.1 91211668 3991904 complement(2620526..2621137) 1 NC_007946.1 hypothetical protein 2621137 3991904 UTI89_C2657 Escherichia coli UTI89 hypothetical protein YP_541654.1 2620526 R 364106 CDS YP_541655.1 91211669 3991905 complement(2621274..2621426) 1 NC_007946.1 hypothetical protein 2621426 3991905 UTI89_C2658 Escherichia coli UTI89 hypothetical protein YP_541655.1 2621274 R 364106 CDS YP_541656.1 91211670 3991906 complement(2621414..2621851) 1 NC_007946.1 hypothetical protein 2621851 3991906 UTI89_C2659 Escherichia coli UTI89 hypothetical protein YP_541656.1 2621414 R 364106 CDS YP_541657.1 91211671 3991907 complement(2621848..2622324) 1 NC_007946.1 bacteriophage HK620 gene R-like; lysin 2622324 3991907 UTI89_C2660 Escherichia coli UTI89 lysin YP_541657.1 2621848 R 364106 CDS YP_541658.1 91211672 3991908 complement(2622308..2622631) 1 NC_007946.1 bacteriophage HK620 gene S-like; holin 2622631 3991908 UTI89_C2661 Escherichia coli UTI89 holin YP_541658.1 2622308 R 364106 CDS YP_541659.1 91211673 3991909 2622856..2623062 1 NC_007946.1 hypothetical protein 2623062 3991909 UTI89_C2662 Escherichia coli UTI89 hypothetical protein YP_541659.1 2622856 D 364106 CDS YP_541660.1 91211674 3991910 complement(2623228..2623746) 1 NC_007946.1 bacteriophage ST64T antitermination protein gp23 2623746 3991910 UTI89_C2663 Escherichia coli UTI89 bacteriophage ST64T antitermination protein gp23 YP_541660.1 2623228 R 364106 CDS YP_541661.1 91211675 3991911 complement(2623743..2623931) 1 NC_007946.1 hypothetical protein 2623931 ninH 3991911 ninH Escherichia coli UTI89 hypothetical protein YP_541661.1 2623743 R 364106 CDS YP_541662.1 91211676 3991912 complement(2623928..2624290) 1 NC_007946.1 Holliday-junction resolvase 2624290 rus 3991912 rus Escherichia coli UTI89 Holliday-junction resolvase YP_541662.1 2623928 R 364106 CDS YP_541663.1 91211677 3991913 complement(2624287..2624577) 1 NC_007946.1 hypothetical protein 2624577 hkbD 3991913 hkbD Escherichia coli UTI89 hypothetical protein YP_541663.1 2624287 R 364106 CDS YP_541664.1 91211678 3991914 complement(2624577..2625299) 1 NC_007946.1 DNA-binding protein Roi 2625299 roi 3991914 roi Escherichia coli UTI89 DNA-binding protein Roi YP_541664.1 2624577 R 364106 CDS YP_541665.1 91211679 3991915 complement(2625461..2625808) 1 NC_007946.1 hypothetical protein 2625808 3991915 UTI89_C2668 Escherichia coli UTI89 hypothetical protein YP_541665.1 2625461 R 364106 CDS YP_541666.1 91211680 3991916 complement(2625811..2625987) 1 NC_007946.1 bacteriophage lambda nin 60-like protein 2625987 ninE2 3991916 ninE2 Escherichia coli UTI89 bacteriophage lambda nin 60-like protein YP_541666.1 2625811 R 364106 CDS YP_541667.1 91211681 3991917 complement(2625984..2626424) 1 NC_007946.1 hypothetical protein 2626424 ninB2 3991917 ninB2 Escherichia coli UTI89 hypothetical protein YP_541667.1 2625984 R 364106 CDS YP_541668.1 91211682 3991918 complement(2626604..2626702) 1 NC_007946.1 bacteriophage HK97 gp56 2626702 3991918 UTI89_C2671 Escherichia coli UTI89 bacteriophage HK97 gp56 YP_541668.1 2626604 R 364106 CDS YP_541669.1 91211683 3991919 complement(2626699..2628075) 1 NC_007946.1 bacteriophage Nil2 gene P DnaB analogue 2628075 3991919 UTI89_C2672 Escherichia coli UTI89 bacteriophage Nil2 gene P DnaB analogue YP_541669.1 2626699 R 364106 CDS YP_541670.1 91211684 3991920 complement(2628072..2628959) 1 NC_007946.1 hypothetical protein 2628959 3991920 UTI89_C2673 Escherichia coli UTI89 hypothetical protein YP_541670.1 2628072 R 364106 CDS YP_541671.1 91211685 3991921 complement(2629022..2629294) 1 NC_007946.1 hypothetical protein 2629294 3991921 UTI89_C2674 Escherichia coli UTI89 hypothetical protein YP_541671.1 2629022 R 364106 CDS YP_541672.1 91211686 3991922 complement(2629317..2629610) 1 NC_007946.1 bacteriophage 343 regulatory protein CII 2629610 3991922 UTI89_C2675 Escherichia coli UTI89 bacteriophage 343 regulatory protein CII YP_541672.1 2629317 R 364106 CDS YP_541673.1 91211687 3991923 complement(2629719..2629904) 1 NC_007946.1 Cro protein 2629904 cro 3991923 cro Escherichia coli UTI89 Cro protein YP_541673.1 2629719 R 364106 CDS YP_541674.1 91211688 3991924 2629985..2630635 1 NC_007946.1 repressor protein 2630635 3991924 UTI89_C2677 Escherichia coli UTI89 repressor protein YP_541674.1 2629985 D 364106 CDS YP_541675.1 91211689 3991925 complement(2630756..2631145) 1 NC_007946.1 hypothetical protein 2631145 3991925 UTI89_C2678 Escherichia coli UTI89 hypothetical protein YP_541675.1 2630756 R 364106 CDS YP_541676.1 91211690 3991926 2631157..2631456 1 NC_007946.1 phage regulatory protein N 2631456 3991926 UTI89_C2679 Escherichia coli UTI89 phage regulatory protein N YP_541676.1 2631157 D 364106 CDS YP_541677.1 91211691 3991927 2631535..2631735 1 NC_007946.1 bacteriophage lambda restriction inhibitor protein ral 2631735 ral 3991927 ral Escherichia coli UTI89 bacteriophage lambda restriction inhibitor protein ral YP_541677.1 2631535 D 364106 CDS YP_541678.1 91211692 3991928 2631794..2632216 1 NC_007946.1 hypothetical protein 2632216 3991928 UTI89_C2681 Escherichia coli UTI89 hypothetical protein YP_541678.1 2631794 D 364106 CDS YP_541679.1 91211693 3991929 2633400..2633531 1 NC_007946.1 protease inhibitor FtsH 2633531 3991929 UTI89_C2682 Escherichia coli UTI89 protease inhibitor FtsH YP_541679.1 2633400 D 364106 CDS YP_541680.1 91211694 3991930 2633516..2633668 1 NC_007946.1 kil protein of bacteriophage HK97 2633668 kil2 3991930 kil2 Escherichia coli UTI89 kil protein of bacteriophage HK97 YP_541680.1 2633516 D 364106 CDS YP_541681.1 91211695 3991552 2633665..2633823 1 NC_007946.1 hypothetical protein 2633823 3991552 UTI89_C2684 Escherichia coli UTI89 hypothetical protein YP_541681.1 2633665 D 364106 CDS YP_541682.1 91211696 3991553 2633744..2633914 1 NC_007946.1 hypothetical protein 2633914 3991553 UTI89_C2685 Escherichia coli UTI89 hypothetical protein YP_541682.1 2633744 D 364106 CDS YP_541683.1 91211697 3991554 2633925..2634530 1 NC_007946.1 bacteriophage HK97 gp40 2634530 erf 3991554 erf Escherichia coli UTI89 bacteriophage HK97 gp40 YP_541683.1 2633925 D 364106 CDS YP_541684.1 91211698 3991555 2634530..2634913 1 NC_007946.1 bacteriophage HK97 gp40 2634913 3991555 UTI89_C2687 Escherichia coli UTI89 bacteriophage HK97 gp40 YP_541684.1 2634530 D 364106 CDS YP_541685.1 91211699 3991556 2634937..2635233 1 NC_007946.1 hypothetical protein 2635233 hkaJ 3991556 hkaJ Escherichia coli UTI89 hypothetical protein YP_541685.1 2634937 D 364106 CDS YP_541686.1 91211700 3991557 2635310..2635846 1 NC_007946.1 hypothetical protein 2635846 hkaH 3991557 hkaH Escherichia coli UTI89 hypothetical protein YP_541686.1 2635310 D 364106 CDS YP_541687.1 91211701 3991558 2636144..2636716 1 NC_007946.1 hypothetical protein 2636716 3991558 UTI89_C2690 Escherichia coli UTI89 hypothetical protein YP_541687.1 2636144 D 364106 CDS YP_541688.1 91211702 3991559 complement(2636939..2637289) 1 NC_007946.1 hypothetical protein 2637289 3991559 UTI89_C2691 Escherichia coli UTI89 hypothetical protein YP_541688.1 2636939 R 364106 CDS YP_541689.1 91211703 3991560 2636993..2637277 1 NC_007946.1 hypothetical protein 2637277 3991560 UTI89_C2692 Escherichia coli UTI89 hypothetical protein YP_541689.1 2636993 D 364106 CDS YP_541690.1 91211704 3991561 2637350..2637517 1 NC_007946.1 hypothetical protein 2637517 3991561 UTI89_C2693 Escherichia coli UTI89 hypothetical protein YP_541690.1 2637350 D 364106 CDS YP_541691.1 91211705 3991562 2637575..2637775 1 NC_007946.1 hypothetical protein 2637775 hkaC 3991562 hkaC Escherichia coli UTI89 hypothetical protein YP_541691.1 2637575 D 364106 CDS YP_541692.1 91211706 3991563 complement(2637962..2638903) 1 NC_007946.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 2638903 dsdC 3991563 dsdC Escherichia coli UTI89 DNA-binding transcriptional regulator DsdC YP_541692.1 2637962 R 364106 CDS YP_541693.1 91211707 3991564 2639115..2640452 1 NC_007946.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2640452 3991564 UTI89_C2696 Escherichia coli UTI89 permease DsdX YP_541693.1 2639115 D 364106 CDS YP_541694.1 91211708 3991565 2640470..2641798 1 NC_007946.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2641798 dsdA 3991565 dsdA Escherichia coli UTI89 D-serine dehydratase YP_541694.1 2640470 D 364106 CDS YP_541695.1 91211709 3991566 complement(2641906..2643444) 1 NC_007946.1 multidrug resistance protein Y 2643444 emrY 3991566 emrY Escherichia coli UTI89 multidrug resistance protein Y YP_541695.1 2641906 R 364106 CDS YP_541696.1 91211710 3991567 2643131..2643469 1 NC_007946.1 hypothetical protein 2643469 3991567 UTI89_C2699 Escherichia coli UTI89 hypothetical protein YP_541696.1 2643131 D 364106 CDS YP_541697.1 91211711 3991568 complement(2643444..2644607) 1 NC_007946.1 multidrug resistance protein K 2644607 emrK 3991568 emrK Escherichia coli UTI89 multidrug resistance protein K YP_541697.1 2643444 R 364106 CDS YP_541698.1 91211712 3991569 2645023..2645637 1 NC_007946.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2645637 evgA 3991569 evgA Escherichia coli UTI89 DNA-binding transcriptional activator EvgA YP_541698.1 2645023 D 364106 CDS YP_541699.1 91211713 3991570 2645642..2649235 1 NC_007946.1 hybrid sensory histidine kinase in two-component regulatory system with EvgA 2649235 evgS 3991570 evgS Escherichia coli UTI89 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_541699.1 2645642 D 364106 CDS YP_541700.1 91211714 3989763 complement(2649291..2650475) 1 NC_007946.1 hypothetical protein 2650475 yfdE 3989763 yfdE Escherichia coli UTI89 hypothetical protein YP_541700.1 2649291 R 364106 CDS YP_541701.1 91211715 3989764 complement(2650510..2651454) 1 NC_007946.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 2651454 yfdV 3989764 yfdV Escherichia coli UTI89 transporter YfdV YP_541701.1 2650510 R 364106 CDS YP_541702.1 91211716 3989765 complement(2651524..2653218) 1 NC_007946.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 2653218 3989765 UTI89_C2705 Escherichia coli UTI89 oxalyl-CoA decarboxylase YP_541702.1 2651524 R 364106 CDS YP_541703.1 91211717 3989766 complement(2653272..2654522) 1 NC_007946.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2654522 yfdW 3989766 yfdW Escherichia coli UTI89 formyl-coenzyme A transferase YP_541703.1 2653272 R 364106 CDS YP_541704.1 91211718 3989767 complement(2655034..2655669) 1 NC_007946.1 hypothetical protein 2655669 yfdX 3989767 yfdX Escherichia coli UTI89 hypothetical protein YP_541704.1 2655034 R 364106 CDS YP_541705.1 91211719 3989768 2655965..2656240 1 NC_007946.1 hypothetical protein 2656240 ypdI 3989768 ypdI Escherichia coli UTI89 hypothetical protein YP_541705.1 2655965 D 364106 CDS YP_541706.1 91211720 3989769 complement(2656317..2656559) 1 NC_007946.1 hypothetical protein 2656559 yfdY 3989769 yfdY Escherichia coli UTI89 hypothetical protein YP_541706.1 2656317 R 364106 CDS YP_541707.1 91211721 3989770 2656846..2657832 1 NC_007946.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2657832 ddg 3989770 ddg Escherichia coli UTI89 lipid A biosynthesis palmitoleoyl acyltransferase YP_541707.1 2656846 D 364106 CDS YP_541708.1 91211722 3989771 complement(2658324..2659562) 1 NC_007946.1 aminotransferase 2659562 3989771 UTI89_C2711 Escherichia coli UTI89 aminotransferase YP_541708.1 2658324 R 364106 CDS YP_541709.1 91211723 3989772 2659939..2661636 1 NC_007946.1 hypothetical protein 2661636 ypdA 3989772 ypdA Escherichia coli UTI89 hypothetical protein YP_541709.1 2659939 D 364106 CDS YP_541710.1 91211724 3989773 2661633..2662388 1 NC_007946.1 hypothetical protein 2662388 ypdB 3989773 ypdB Escherichia coli UTI89 hypothetical protein YP_541710.1 2661633 D 364106 CDS YP_541711.1 91211725 3989774 2662401..2663258 1 NC_007946.1 transcriptional regulator YpdC 2663258 ypdC 3989774 ypdC Escherichia coli UTI89 transcriptional regulator YpdC YP_541711.1 2662401 D 364106 CDS YP_541712.1 91211726 3989775 complement(2663261..2665756) 1 NC_007946.1 phosphoenolpyruvate-protein phosphotransferase ypdD 2665756 3989775 UTI89_C2715 Escherichia coli UTI89 phosphoenolpyruvate-protein phosphotransferase ypdD YP_541712.1 2663261 R 364106 CDS YP_541713.1 91211727 3989776 complement(2665781..2666818) 1 NC_007946.1 metalloprotein; exoaminopeptidase 2666818 ypdE 3989776 ypdE Escherichia coli UTI89 exoaminopeptidase YP_541713.1 2665781 R 364106 CDS YP_541714.1 91211728 3989777 complement(2666818..2667903) 1 NC_007946.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2667903 3989777 UTI89_C2717 Escherichia coli UTI89 aminopeptidase YP_541714.1 2666818 R 364106 CDS YP_541715.1 91211729 3989778 complement(2667919..2669166) 1 NC_007946.1 transport protein 2669166 3989778 UTI89_C2718 Escherichia coli UTI89 transport protein YP_541715.1 2667919 R 364106 CDS YP_541716.1 91211730 3989779 complement(2669188..2669565) 1 NC_007946.1 PTS system IIB component YpdH 2669565 3989779 UTI89_C2719 Escherichia coli UTI89 PTS system IIB component YpdH YP_541716.1 2669188 R 364106 CDS YP_541717.1 91211731 3989780 complement(2669733..2670698) 1 NC_007946.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2670698 glk 3989780 glk Escherichia coli UTI89 glucokinase YP_541717.1 2669733 R 364106 CDS YP_541718.1 91211732 3989781 2670902..2672158 1 NC_007946.1 hypothetical protein 2672158 yfeO 3989781 yfeO Escherichia coli UTI89 hypothetical protein YP_541718.1 2670902 D 364106 CDS YP_541719.1 91211733 3989782 2672273..2672599 1 NC_007946.1 hypothetical protein 2672599 ypeC 3989782 ypeC Escherichia coli UTI89 hypothetical protein YP_541719.1 2672273 D 364106 CDS YP_541721.1 91211735 3991686 complement(2672740..2673978) 1 NC_007946.1 manganese transport protein MntH 2673978 mntH 3991686 mntH Escherichia coli UTI89 manganese transport protein MntH YP_541721.1 2672740 R 364106 CDS YP_541722.1 91211736 3991687 2674275..2675516 1 NC_007946.1 nucleoside permease NupC 2675516 nupC 3991687 nupC Escherichia coli UTI89 nucleoside permease NupC YP_541722.1 2674275 D 364106 CDS YP_541723.1 91211737 3991688 complement(2675566..2677815) 1 NC_007946.1 hypothetical protein 2677815 yfeA 3991688 yfeA Escherichia coli UTI89 hypothetical protein YP_541723.1 2675566 R 364106 CDS YP_541724.1 91211738 3991691 2678373..2678732 1 NC_007946.1 hypothetical protein 2678732 yfeC 3991691 yfeC Escherichia coli UTI89 hypothetical protein YP_541724.1 2678373 D 364106 CDS YP_541725.1 91211739 3991692 2678734..2679126 1 NC_007946.1 hypothetical protein 2679126 yfeD 3991692 yfeD Escherichia coli UTI89 hypothetical protein YP_541725.1 2678734 D 364106 CDS YP_541726.1 91211740 3991693 complement(2679177..2680592) 1 NC_007946.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2680592 gltX 3991693 gltX Escherichia coli UTI89 glutamyl-tRNA synthetase YP_541726.1 2679177 R 364106 CDS YP_541727.1 91211741 3989901 complement(2681359..2682258) 1 NC_007946.1 DNA-binding transcriptional activator XapR 2682258 xapR 3989901 xapR Escherichia coli UTI89 DNA-binding transcriptional activator XapR YP_541727.1 2681359 R 364106 CDS YP_541728.1 91211742 3989902 complement(2682284..2682442) 1 NC_007946.1 hypothetical protein 2682442 3989902 UTI89_C2737 Escherichia coli UTI89 hypothetical protein YP_541728.1 2682284 R 364106 CDS YP_541729.1 91211743 3989903 complement(2682495..2683751) 1 NC_007946.1 xanthosine permease 2683751 xapB 3989903 xapB Escherichia coli UTI89 xanthosine permease YP_541729.1 2682495 R 364106 CDS YP_541730.1 91211744 3989904 complement(2683812..2684645) 1 NC_007946.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2684645 xapA 3989904 xapA Escherichia coli UTI89 purine nucleoside phosphorylase YP_541730.1 2683812 R 364106 CDS YP_541731.1 91211745 3989905 complement(2685697..2686623) 1 NC_007946.1 LysR family transcriptional regulator 2686623 yfeR 3989905 yfeR Escherichia coli UTI89 LysR family transcriptional regulator YP_541731.1 2685697 R 364106 CDS YP_541732.1 91211746 3989906 2686713..2687711 1 NC_007946.1 cytochrome oxidase 2687711 yfeH 3989906 yfeH Escherichia coli UTI89 cytochrome oxidase YP_541732.1 2686713 D 364106 CDS YP_541733.1 91211747 3989907 complement(2687708..2687926) 1 NC_007946.1 hypothetical protein 2687926 3989907 UTI89_C2742 Escherichia coli UTI89 hypothetical protein YP_541733.1 2687708 R 364106 CDS YP_541734.1 91211748 3989908 complement(2687928..2689943) 1 NC_007946.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2689943 ligA 3989908 ligA Escherichia coli UTI89 NAD-dependent DNA ligase LigA YP_541734.1 2687928 R 364106 CDS YP_541735.1 91211749 3989909 complement(2690014..2691063) 1 NC_007946.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2691063 zipA 3989909 zipA Escherichia coli UTI89 cell division protein ZipA YP_541735.1 2690014 R 364106 CDS YP_541736.1 91211750 3989910 2690481..2690786 1 NC_007946.1 regulatory protein AlgP 2690786 algP 3989910 algP Escherichia coli UTI89 regulatory protein AlgP YP_541736.1 2690481 D 364106 CDS YP_541737.1 91211751 3989911 2691242..2692003 1 NC_007946.1 role in sulfur assimilation; sulfate transport protein CysZ 2692003 cysZ 3989911 cysZ Escherichia coli UTI89 sulfate transport protein CysZ YP_541737.1 2691242 D 364106 CDS YP_541738.1 91211752 3989912 2692188..2693159 1 NC_007946.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2693159 cysK 3989912 cysK Escherichia coli UTI89 cysteine synthase A YP_541738.1 2692188 D 364106 CDS YP_541739.1 91211753 3989913 complement(2693477..2693770) 1 NC_007946.1 hypothetical protein 2693770 3989913 UTI89_C2748 Escherichia coli UTI89 hypothetical protein YP_541739.1 2693477 R 364106 CDS YP_541740.1 91211754 3989914 2693543..2693800 1 NC_007946.1 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 2693800 ptsH 3989914 ptsH Escherichia coli UTI89 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr YP_541740.1 2693543 D 364106 CDS YP_541741.1 91211755 3989915 2693845..2695572 1 NC_007946.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2695572 ptsI 3989915 ptsI Escherichia coli UTI89 phosphoenolpyruvate-protein phosphotransferase YP_541741.1 2693845 D 364106 CDS YP_541742.1 91211756 3989916 2695613..2696122 1 NC_007946.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 2696122 crr 3989916 crr Escherichia coli UTI89 PTS system glucose-specific transporter subunit YP_541742.1 2695613 D 364106 CDS YP_541743.1 91211757 3989917 complement(2696165..2697016) 1 NC_007946.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2697016 pdxK 3989917 pdxK Escherichia coli UTI89 pyridoxal kinase YP_541743.1 2696165 R 364106 CDS YP_541744.1 91211758 3989918 2697121..2697489 1 NC_007946.1 hypothetical protein 2697489 yfeK 3989918 yfeK Escherichia coli UTI89 hypothetical protein YP_541744.1 2697121 D 364106 CDS YP_541745.1 91211759 3989919 complement(2697492..2698403) 1 NC_007946.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2698403 cysM 3989919 cysM Escherichia coli UTI89 cysteine synthase B YP_541745.1 2697492 R 364106 CDS YP_541746.1 91211760 3989743 complement(2698538..2699635) 1 NC_007946.1 sulfate/thiosulfate transporter subunit 2699635 cysA 3989743 cysA Escherichia coli UTI89 sulfate/thiosulfate transporter subunit YP_541746.1 2698538 R 364106 CDS YP_541747.1 91211761 3989744 complement(2699625..2700500) 1 NC_007946.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2700500 cysW 3989744 cysW Escherichia coli UTI89 sulfate/thiosulfate transporter permease subunit YP_541747.1 2699625 R 364106 CDS YP_541748.1 91211762 3989745 complement(2700500..2701333) 1 NC_007946.1 sulfate/thiosulfate transporter subunit 2701333 cysU 3989745 cysU Escherichia coli UTI89 sulfate/thiosulfate transporter subunit YP_541748.1 2700500 R 364106 CDS YP_541749.1 91211763 3989746 complement(2701333..2702349) 1 NC_007946.1 thiosulfate transporter subunit 2702349 cysP 3989746 cysP Escherichia coli UTI89 thiosulfate transporter subunit YP_541749.1 2701333 R 364106 CDS YP_541750.1 91211764 3989747 complement(2702507..2703364) 1 NC_007946.1 short chain dehydrogenase 2703364 ucpA 3989747 ucpA Escherichia coli UTI89 short chain dehydrogenase YP_541750.1 2702507 R 364106 CDS YP_541751.1 91211765 3989748 2703578..2704474 1 NC_007946.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 2704474 murQ 3989748 murQ Escherichia coli UTI89 N-acetylmuramic acid-6-phosphate etherase YP_541751.1 2703578 D 364106 CDS YP_541752.1 91211766 3989749 2704478..2705902 1 NC_007946.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 2705902 murP 3989749 murP Escherichia coli UTI89 PTS system N-acetylmuramic acid transporter subunits EIIBC YP_541752.1 2704478 D 364106 CDS YP_541753.1 91211767 3989750 complement(2705922..2706065) 1 NC_007946.1 hypothetical protein 2706065 3989750 UTI89_C2762 Escherichia coli UTI89 hypothetical protein YP_541753.1 2705922 R 364106 CDS YP_541754.1 91211768 3989751 2706065..2706991 1 NC_007946.1 hypothetical protein 2706991 3989751 UTI89_C2763 Escherichia coli UTI89 hypothetical protein YP_541754.1 2706065 D 364106 CDS YP_541755.1 91211769 3989752 complement(2706080..2707006) 1 NC_007946.1 hypothetical protein 2707006 yfeX 3989752 yfeX Escherichia coli UTI89 hypothetical protein YP_541755.1 2706080 R 364106 CDS YP_541756.1 91211770 3989753 complement(2707075..2707650) 1 NC_007946.1 hypothetical protein 2707650 yfeY 3989753 yfeY Escherichia coli UTI89 hypothetical protein YP_541756.1 2707075 R 364106 CDS YP_541757.1 91211771 3989754 complement(2707711..2708166) 1 NC_007946.1 hypothetical protein 2708166 yfeZ 3989754 yfeZ Escherichia coli UTI89 hypothetical protein YP_541757.1 2707711 R 364106 CDS YP_541758.1 91211772 3989755 complement(2708147..2708683) 1 NC_007946.1 acetyltransferase 2708683 ypeA 3989755 ypeA Escherichia coli UTI89 acetyltransferase YP_541758.1 2708147 R 364106 CDS YP_541759.1 91211773 3989756 2708786..2709655 1 NC_007946.1 N-acetylmuramoyl-L-alanine amidase 2709655 amiA 3989756 amiA Escherichia coli UTI89 N-acetylmuramoyl-L-alanine amidase YP_541759.1 2708786 D 364106 CDS YP_541760.1 91211774 3989757 2709656..2710558 1 NC_007946.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2710558 hemF 3989757 hemF Escherichia coli UTI89 coproporphyrinogen III oxidase YP_541760.1 2709656 D 364106 CDS YP_541761.1 91211775 3989758 complement(2710564..2711616) 1 NC_007946.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2711616 yfeG 3989758 yfeG Escherichia coli UTI89 transcriptional regulator EutR YP_541761.1 2710564 R 364106 CDS YP_541762.1 91211776 3989759 complement(2711662..2712168) 1 NC_007946.1 synonym: b2438, yffI; ethanolamine utilization protein EutK 2712168 eutK 3989759 eutK Escherichia coli UTI89 ethanolamine utilization protein EutK YP_541762.1 2711662 R 364106 CDS YP_541763.1 91211777 3989760 complement(2712175..2712834) 1 NC_007946.1 synonym: yffJ, b2439; ethanolamine utilization protein EutL 2712834 eutL 3989760 eutL Escherichia coli UTI89 ethanolamine utilization protein EutL YP_541763.1 2712175 R 364106 CDS YP_541764.1 91211778 3989761 complement(2712844..2713731) 1 NC_007946.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2713731 eutC 3989761 eutC Escherichia coli UTI89 ethanolamine ammonia-lyase small subunit YP_541764.1 2712844 R 364106 CDS YP_541765.1 91211779 3989762 complement(2713752..2715113) 1 NC_007946.1 regulatory subunit of ethanolamine ammonia-lyase 2715113 eutB 3989762 eutB Escherichia coli UTI89 regulatory subunit of ethanolamine ammonia-lyase YP_541765.1 2713752 R 364106 CDS YP_541766.1 91211780 3990132 complement(2715125..2716528) 1 NC_007946.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2716528 eutA 3990132 eutA Escherichia coli UTI89 reactivating factor for ethanolamine ammonia lyase YP_541766.1 2715125 R 364106 CDS YP_541767.1 91211781 3990133 complement(2716525..2717751) 1 NC_007946.1 synonym: yffU, b2452; ethanolamine utilization transport protein EutH 2717751 eutH 3990133 eutH Escherichia coli UTI89 ethanolamine utilization transport protein EutH YP_541767.1 2716525 R 364106 CDS YP_541768.1 91211782 3990134 complement(2717968..2719182) 1 NC_007946.1 synonym: yffV, b2453; ethanolamine utilization protein EutG iron-containing alcohol dehydrogenase 2719182 eutG 3990134 eutG Escherichia coli UTI89 ethanolamine utilization protein EutG iron-containing alcohol dehydrogenase YP_541768.1 2717968 R 364106 CDS YP_541769.1 91211783 3990135 complement(2719145..2719981) 1 NC_007946.1 synonym: yffW, b2454; ethanolamine utilization protein EutJ 2719981 eutJ 3990135 eutJ Escherichia coli UTI89 ethanolamine utilization protein EutJ YP_541769.1 2719145 R 364106 CDS YP_541770.1 91211784 3990136 complement(2719992..2721395) 1 NC_007946.1 synonym: yffX, b2455; ethanolamine utilization protein EutE acetaldehyde dehydrogenase 2721395 eutE 3990136 eutE Escherichia coli UTI89 ethanolamine utilization protein EutE acetaldehyde dehydrogenase YP_541770.1 2719992 R 364106 CDS YP_541771.1 91211785 3990137 complement(2721407..2721694) 1 NC_007946.1 synonym: yffY, b2456, cchB; detox protein 2721694 eutN 3990137 eutN Escherichia coli UTI89 detox protein YP_541771.1 2721407 R 364106 CDS YP_541772.1 91211786 3990138 complement(2721801..2722136) 1 NC_007946.1 synonym: yffZ, b2457, cchA; detox protein 2722136 eutM 3990138 eutM Escherichia coli UTI89 detox protein YP_541772.1 2721801 R 364106 CDS YP_541773.1 91211787 3990139 complement(2722133..2723149) 1 NC_007946.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2723149 eutD 3990139 eutD Escherichia coli UTI89 phosphotransacetylase YP_541773.1 2722133 R 364106 CDS YP_541774.1 91211788 3990140 complement(2723146..2723949) 1 NC_007946.1 ethanolamine utilization cobalamin adenosyltransferase 2723949 eutT 3990140 eutT Escherichia coli UTI89 ethanolamine utilization cobalamin adenosyltransferase YP_541774.1 2723146 R 364106 CDS YP_541775.1 91211789 3990141 complement(2723946..2724647) 1 NC_007946.1 ethanolamine utilization protein EutQ 2724647 eutQ 3990141 eutQ Escherichia coli UTI89 ethanolamine utilization protein EutQ YP_541775.1 2723946 R 364106 CDS YP_541776.1 91211790 3990142 complement(2724622..2725101) 1 NC_007946.1 ethanolamine utilization protein EutP 2725101 eutP 3990142 eutP Escherichia coli UTI89 ethanolamine utilization protein EutP YP_541776.1 2724622 R 364106 CDS YP_541777.1 91211791 3990143 complement(2725114..2725521) 1 NC_007946.1 ethanolamine utilization protein EutS 2725521 eutS 3990143 eutS Escherichia coli UTI89 ethanolamine utilization protein EutS YP_541777.1 2725114 R 364106 CDS YP_541778.1 91211792 3990144 complement(2725742..2728021) 1 NC_007946.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2728021 maeB 3990144 maeB Escherichia coli UTI89 malic enzyme YP_541778.1 2725742 R 364106 CDS YP_541779.1 91211793 3990145 2728310..2729260 1 NC_007946.1 synonym: b2464, G7294, alaT; transaldolase A 2729260 talA 3990145 talA Escherichia coli UTI89 transaldolase A YP_541779.1 2728310 D 364106 CDS YP_541780.2 162138397 3990146 2729280..2731283 1 NC_007946.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2731283 tktB 3990146 tktB Escherichia coli UTI89 transketolase YP_541780.2 2729280 D 364106 CDS YP_541781.1 91211795 3990147 complement(2731360..2732403) 1 NC_007946.1 hypothetical protein 2732403 ypfG 3990147 ypfG Escherichia coli UTI89 hypothetical protein YP_541781.1 2731360 R 364106 CDS YP_541782.1 91211796 3990148 complement(2732297..2732428) 1 NC_007946.1 hypothetical protein 2732428 3990148 UTI89_C2791 Escherichia coli UTI89 hypothetical protein YP_541782.1 2732297 R 364106 CDS YP_541783.1 91211797 3990149 2732303..2732563 1 NC_007946.1 hypothetical protein 2732563 3990149 UTI89_C2792 Escherichia coli UTI89 hypothetical protein YP_541783.1 2732303 D 364106 CDS YP_541784.1 91211798 3990150 complement(2732529..2733131) 1 NC_007946.1 hypothetical protein 2733131 yffH 3990150 yffH Escherichia coli UTI89 hypothetical protein YP_541784.1 2732529 R 364106 CDS YP_541785.1 91211799 3990558 complement(2733172..2735151) 1 NC_007946.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 2735151 aegA 3990558 aegA Escherichia coli UTI89 oxidoreductase Fe-S binding subunit YP_541785.1 2733172 R 364106 CDS YP_541786.1 91211800 3990559 2735342..2737057 1 NC_007946.1 nitrate/nitrite sensor protein NarQ 2737057 narQ 3990559 narQ Escherichia coli UTI89 nitrate/nitrite sensor protein NarQ YP_541786.1 2735342 D 364106 CDS YP_541787.1 91211801 3990560 2737221..2740334 1 NC_007946.1 synonym: b2470, yffA; aminoglycoside/multidrug efflux system 2740334 acrD 3990560 acrD Escherichia coli UTI89 aminoglycoside/multidrug efflux system YP_541787.1 2737221 D 364106 CDS YP_541788.1 91211802 3990561 2740873..2741229 1 NC_007946.1 hypothetical protein 2741229 yffB 3990561 yffB Escherichia coli UTI89 hypothetical protein YP_541788.1 2740873 D 364106 CDS YP_541789.1 91211803 3990562 2741233..2742360 1 NC_007946.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2742360 dapE 3990562 dapE Escherichia coli UTI89 succinyl-diaminopimelate desuccinylase YP_541789.1 2741233 D 364106 CDS YP_541790.1 91211804 3990563 2742388..2742588 1 NC_007946.1 hypothetical protein 2742588 3990563 UTI89_C2799 Escherichia coli UTI89 hypothetical protein YP_541790.1 2742388 D 364106 CDS YP_541791.2 162138396 3990564 complement(2742669..2743367) 1 NC_007946.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 2743367 ypfH 3990564 ypfH Escherichia coli UTI89 esterase YP_541791.2 2742669 R 364106 CDS YP_541792.1 91211806 3990565 complement(2743441..2745456) 1 NC_007946.1 hypothetical protein 2745456 ypfI 3990565 ypfI Escherichia coli UTI89 hypothetical protein YP_541792.1 2743441 R 364106 CDS YP_541793.1 91211807 3990566 complement(2745471..2746334) 1 NC_007946.1 hypothetical protein 2746334 ypfJ 3990566 ypfJ Escherichia coli UTI89 hypothetical protein YP_541793.1 2745471 R 364106 CDS YP_541794.1 91211808 3990567 complement(2746502..2747224) 1 NC_007946.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2747224 purC 3990567 purC Escherichia coli UTI89 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_541794.1 2746502 R 364106 CDS YP_541795.1 91211809 3990568 complement(2747428..2748465) 1 NC_007946.1 lipoprotein 2748465 nlpB 3990568 nlpB Escherichia coli UTI89 lipoprotein YP_541795.1 2747428 R 364106 CDS YP_541796.1 91211810 3990569 complement(2748479..2749375) 1 NC_007946.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2749375 dapA 3990569 dapA Escherichia coli UTI89 dihydrodipicolinate synthase YP_541796.1 2748479 R 364106 CDS YP_541797.2 162138395 3990570 2749503..2750075 1 NC_007946.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2750075 gcvR 3990570 gcvR Escherichia coli UTI89 glycine cleavage system transcriptional repressor YP_541797.2 2749503 D 364106 CDS YP_541798.1 91211812 3990571 2750075..2750545 1 NC_007946.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2750545 bcp 3990571 bcp Escherichia coli UTI89 thioredoxin-dependent thiol peroxidase YP_541798.1 2750075 D 364106 CDS YP_541799.1 91211813 3990572 complement(2750644..2751705) 1 NC_007946.1 permease PerM 2751705 perM 3990572 perM Escherichia coli UTI89 permease PerM YP_541799.1 2750644 R 364106 CDS YP_541800.1 91211814 3990573 2751736..2751912 1 NC_007946.1 hypothetical protein 2751912 3990573 UTI89_C2809 Escherichia coli UTI89 hypothetical protein YP_541800.1 2751736 D 364106 CDS YP_541801.1 91211815 3990574 2751918..2753381 1 NC_007946.1 hypothetical protein 2753381 yfgC 3990574 yfgC Escherichia coli UTI89 hypothetical protein YP_541801.1 2751918 D 364106 CDS YP_541802.1 91211816 3990575 2753402..2753761 1 NC_007946.1 oxidoreductase 2753761 yfgD 3990575 yfgD Escherichia coli UTI89 oxidoreductase YP_541802.1 2753402 D 364106 CDS YP_541803.1 91211817 3990576 complement(2753899..2754645) 1 NC_007946.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2754645 yfgE 3990576 yfgE Escherichia coli UTI89 DNA replication initiation factor YP_541803.1 2753899 R 364106 CDS YP_541804.1 91211818 3990577 complement(2754695..2756026) 1 NC_007946.1 uracil transporter 2756026 uraA 3990577 uraA Escherichia coli UTI89 uracil transporter YP_541804.1 2754695 R 364106 CDS YP_541805.1 91211819 3992162 complement(2756070..2756723) 1 NC_007946.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2756723 upp 3992162 upp Escherichia coli UTI89 uracil phosphoribosyltransferase YP_541805.1 2756070 R 364106 CDS YP_541806.1 91211820 3992163 2757020..2758057 1 NC_007946.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2758057 purM 3992163 purM Escherichia coli UTI89 phosphoribosylaminoimidazole synthetase YP_541806.1 2757020 D 364106 CDS YP_541807.1 91211821 3992164 2758057..2758695 1 NC_007946.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2758695 purN 3992164 purN Escherichia coli UTI89 phosphoribosylglycinamide formyltransferase YP_541807.1 2758057 D 364106 CDS YP_541808.1 91211822 3992165 2758861..2760933 1 NC_007946.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2760933 ppk 3992165 ppk Escherichia coli UTI89 polyphosphate kinase YP_541808.1 2758861 D 364106 CDS YP_541809.1 91211823 3992166 2760938..2762479 1 NC_007946.1 exopolyphosphatase 2762479 ppx 3992166 ppx Escherichia coli UTI89 exopolyphosphatase YP_541809.1 2760938 D 364106 CDS YP_541810.1 91211824 3992167 complement(2762518..2764761) 1 NC_007946.1 hypothetical protein 2764761 yfgF 3992167 yfgF Escherichia coli UTI89 hypothetical protein YP_541810.1 2762518 R 364106 CDS YP_541811.1 91211825 3992168 complement(2764943..2765095) 1 NC_007946.1 hypothetical protein 2765095 3992168 UTI89_C2820 Escherichia coli UTI89 hypothetical protein YP_541811.1 2764943 R 364106 CDS YP_541812.1 91211826 3992169 complement(2764978..2765268) 1 NC_007946.1 hypothetical protein 2765268 3992169 UTI89_C2821 Escherichia coli UTI89 hypothetical protein YP_541812.1 2764978 R 364106 CDS YP_541813.1 91211827 3992170 2765113..2765304 1 NC_007946.1 hypothetical protein 2765304 3992170 UTI89_C2822 Escherichia coli UTI89 hypothetical protein YP_541813.1 2765113 D 364106 CDS YP_541814.1 91211828 3992171 2765615..2766133 1 NC_007946.1 outer membrane lipoprotein 2766133 yfgH 3992171 yfgH Escherichia coli UTI89 outer membrane lipoprotein YP_541814.1 2765615 D 364106 CDS YP_541815.1 91211829 3992172 2766149..2766688 1 NC_007946.1 hypothetical protein 2766688 yfgI 3992172 yfgI Escherichia coli UTI89 hypothetical protein YP_541815.1 2766149 D 364106 CDS YP_541816.1 91211830 3992173 complement(2766782..2768359) 1 NC_007946.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2768359 guaA 3992173 guaA Escherichia coli UTI89 GMP synthase YP_541816.1 2766782 R 364106 CDS YP_541817.1 91211831 3992174 complement(2768428..2769963) 1 NC_007946.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2769963 guaB 3992174 guaB Escherichia coli UTI89 inosine 5'-monophosphate dehydrogenase YP_541817.1 2768428 R 364106 CDS YP_541818.1 91211832 3992175 2770056..2771432 1 NC_007946.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2771432 xseA 3992175 xseA Escherichia coli UTI89 exodeoxyribonuclease VII large subunit YP_541818.1 2770056 D 364106 CDS YP_541819.1 91211833 3992176 complement(2771501..2779552) 1 NC_007946.1 RatA-like protein 2779552 3992176 UTI89_C2828 Escherichia coli UTI89 RatA-like protein YP_541819.1 2771501 R 364106 CDS YP_541820.1 91211834 3992177 complement(2779673..2780650) 1 NC_007946.1 SinI-like protein 2780650 sinI 3992177 sinI Escherichia coli UTI89 SinI-like protein YP_541820.1 2779673 R 364106 CDS YP_541821.1 91211835 3992178 complement(2780705..2782939) 1 NC_007946.1 SinH-like protein 2782939 3992178 UTI89_C2830 Escherichia coli UTI89 SinH-like protein YP_541821.1 2780705 R 364106 CDS YP_541822.1 91211836 3992179 complement(2783118..2783333) 1 NC_007946.1 hypothetical protein 2783333 yfgJ 3992179 yfgJ Escherichia coli UTI89 hypothetical protein YP_541822.1 2783118 R 364106 CDS YP_541823.2 162138394 3992180 complement(2783396..2784868) 1 NC_007946.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2784868 engA 3992180 engA Escherichia coli UTI89 GTP-binding protein EngA YP_541823.2 2783396 R 364106 CDS YP_541824.1 91211838 3990171 complement(2784986..2786164) 1 NC_007946.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2786164 yfgL 3990171 yfgL Escherichia coli UTI89 outer membrane protein assembly complex subunit YfgL YP_541824.1 2784986 R 364106 CDS YP_541825.1 91211839 3990172 complement(2786175..2786795) 1 NC_007946.1 hypothetical protein 2786795 yfgM 3990172 yfgM Escherichia coli UTI89 hypothetical protein YP_541825.1 2786175 R 364106 CDS YP_541826.1 91211840 3990173 complement(2786813..2788087) 1 NC_007946.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2788087 hisS 3990173 hisS Escherichia coli UTI89 histidyl-tRNA synthetase YP_541826.1 2786813 R 364106 CDS YP_541827.1 91211841 3990174 complement(2788198..2789316) 1 NC_007946.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2789316 ispG 3990174 ispG Escherichia coli UTI89 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_541827.1 2788198 R 364106 CDS YP_541828.1 91211842 3990175 complement(2789343..2790350) 1 NC_007946.1 cytoskeletal protein RodZ 2790350 yfgA 3990175 yfgA Escherichia coli UTI89 cytoskeletal protein RodZ YP_541828.1 2789343 R 364106 CDS YP_541829.1 91211843 3990176 complement(2790635..2791789) 1 NC_007946.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2791789 yfgB 3990176 yfgB Escherichia coli UTI89 ribosomal RNA large subunit methyltransferase N YP_541829.1 2790635 R 364106 CDS YP_541830.1 91211844 3990177 2791915..2792433 1 NC_007946.1 hypothetical protein 2792433 3990177 UTI89_C2839 Escherichia coli UTI89 hypothetical protein YP_541830.1 2791915 D 364106 CDS YP_541831.1 91211845 3990178 complement(2791939..2792370) 1 NC_007946.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2792370 ndk 3990178 ndk Escherichia coli UTI89 nucleoside diphosphate kinase YP_541831.1 2791939 R 364106 CDS YP_541832.1 91211846 3990179 complement(2792519..2794831) 1 NC_007946.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2794831 pbpC 3990179 pbpC Escherichia coli UTI89 penicillin-binding protein 1C YP_541832.1 2792519 R 364106 CDS YP_541833.1 91211847 3990180 complement(2794832..2799793) 1 NC_007946.1 lipoprotein YfhM 2799793 yfhM 3990180 yfhM Escherichia coli UTI89 lipoprotein YfhM YP_541833.1 2794832 R 364106 CDS YP_541834.2 162138393 3990181 2800000..2800845 1 NC_007946.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2800845 sseA 3990181 sseA Escherichia coli UTI89 3-mercaptopyruvate sulfurtransferase YP_541834.2 2800000 D 364106 CDS YP_541835.2 162138392 3990182 complement(2801338..2802114) 1 NC_007946.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2802114 sseB 3990182 sseB Escherichia coli UTI89 enhanced serine sensitivity protein SseB YP_541835.2 2801338 R 364106 CDS YP_541836.1 91211850 3990183 complement(2802256..2803539) 1 NC_007946.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 2803539 pepB 3990183 pepB Escherichia coli UTI89 aminopeptidase YP_541836.1 2802256 R 364106 CDS YP_541837.1 91211851 3990184 complement(2803598..2803798) 1 NC_007946.1 hypothetical protein 2803798 yfhJ 3990184 yfhJ Escherichia coli UTI89 hypothetical protein YP_541837.1 2803598 R 364106 CDS YP_541838.1 91211852 3990185 complement(2803810..2804145) 1 NC_007946.1 (2Fe-2S)-binding protein 2804145 fdx 3990185 fdx Escherichia coli UTI89 (2Fe-2S)-binding protein YP_541838.1 2803810 R 364106 CDS YP_541839.2 162138391 3990186 complement(2804147..2805997) 1 NC_007946.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2805997 hscA 3990186 hscA Escherichia coli UTI89 chaperone protein HscA YP_541839.2 2804147 R 364106 CDS YP_541840.1 91211854 3990187 complement(2806014..2806529) 1 NC_007946.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2806529 hscB 3990187 hscB Escherichia coli UTI89 co-chaperone HscB YP_541840.1 2806014 R 364106 CDS YP_541841.1 91211855 3990188 complement(2806625..2806954) 1 NC_007946.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2806954 iscA 3990188 iscA Escherichia coli UTI89 iron-sulfur cluster assembly protein YP_541841.1 2806625 R 364106 CDS YP_541842.1 91211856 3990189 complement(2806965..2807351) 1 NC_007946.1 synonym: yfhN, nifU, b2529; scaffold protein 2807351 iscU 3990189 iscU Escherichia coli UTI89 scaffold protein YP_541842.1 2806965 R 364106 CDS YP_541843.1 91211857 3990190 complement(2807379..2808617) 1 NC_007946.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2808617 iscS 3990190 iscS Escherichia coli UTI89 cysteine desulfurase YP_541843.1 2807379 R 364106 CDS YP_541844.1 91211858 3990191 complement(2808705..2809193) 1 NC_007946.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2809193 iscR 3990191 iscR Escherichia coli UTI89 DNA-binding transcriptional regulator IscR YP_541844.1 2808705 R 364106 CDS YP_541845.1 91211859 3990192 complement(2809463..2810203) 1 NC_007946.1 ATP synthase subunit beta 2810203 yfhQ 3990192 yfhQ Escherichia coli UTI89 ATP synthase subunit beta YP_541845.1 2809463 R 364106 CDS YP_541846.1 91211860 3990193 2810322..2811125 1 NC_007946.1 inositol monophosphatase 2811125 suhB 3990193 suhB Escherichia coli UTI89 inositol monophosphatase YP_541846.1 2810322 D 364106 CDS YP_541847.1 91211861 3990194 2811243..2812124 1 NC_007946.1 hypothetical protein 2812124 3990194 UTI89_C2856 Escherichia coli UTI89 hypothetical protein YP_541847.1 2811243 D 364106 CDS YP_541848.2 162138390 3990195 2812315..2813595 1 NC_007946.1 stationary phase inducible protein CsiE 2813595 csiE 3990195 csiE Escherichia coli UTI89 stationary phase inducible protein CsiE YP_541848.2 2812315 D 364106 CDS YP_541849.1 91211863 3990196 complement(2813587..2814726) 1 NC_007946.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 2814726 hcaT 3990196 hcaT Escherichia coli UTI89 3-phenylpropionic acid transporter YP_541849.1 2813587 R 364106 CDS YP_541850.1 91211864 3990197 complement(2814760..2814903) 1 NC_007946.1 hypothetical protein 2814903 3990197 UTI89_C2859 Escherichia coli UTI89 hypothetical protein YP_541850.1 2814760 R 364106 CDS YP_541851.1 91211865 3990198 2814946..2815098 1 NC_007946.1 hypothetical protein 2815098 3990198 UTI89_C2860 Escherichia coli UTI89 hypothetical protein YP_541851.1 2814946 D 364106 CDS YP_541852.1 91211866 3990199 2815050..2815517 1 NC_007946.1 hypothetical protein 2815517 yphA 3990199 yphA Escherichia coli UTI89 hypothetical protein YP_541852.1 2815050 D 364106 CDS YP_541853.1 91211867 3990200 complement(2815305..2815613) 1 NC_007946.1 hypothetical protein 2815613 3990200 UTI89_C2862 Escherichia coli UTI89 hypothetical protein YP_541853.1 2815305 R 364106 CDS YP_541854.1 91211868 3990201 complement(2815677..2816549) 1 NC_007946.1 hypothetical protein 2816549 yphB 3990201 yphB Escherichia coli UTI89 hypothetical protein YP_541854.1 2815677 R 364106 CDS YP_541855.1 91211869 3990202 complement(2816561..2817655) 1 NC_007946.1 sorbitol dehydrogenase 2817655 gutB 3990202 gutB Escherichia coli UTI89 sorbitol dehydrogenase YP_541855.1 2816561 R 364106 CDS YP_541856.1 91211870 3990203 complement(2817688..2818686) 1 NC_007946.1 ABC transporter permease 2818686 yphD 3990203 yphD Escherichia coli UTI89 ABC transporter permease YP_541856.1 2817688 R 364106 CDS YP_541857.1 91211871 3990204 complement(2818711..2820222) 1 NC_007946.1 ABC transporter ATP-binding protein 2820222 yphE 3990204 yphE Escherichia coli UTI89 ABC transporter ATP-binding protein YP_541857.1 2818711 R 364106 CDS YP_541858.1 91211872 3990205 complement(2820245..2821228) 1 NC_007946.1 ABC transporter periplasmic-binding protein 2821228 yphF 3990205 yphF Escherichia coli UTI89 ABC transporter periplasmic-binding protein YP_541858.1 2820245 R 364106 CDS YP_541859.1 91211873 3990206 complement(2821325..2824699) 1 NC_007946.1 hypothetical protein 2824699 yphG 3990206 yphG Escherichia coli UTI89 hypothetical protein YP_541859.1 2821325 R 364106 CDS YP_541860.1 91211874 3990207 2824724..2825917 1 NC_007946.1 hypothetical protein 2825917 yphH 3990207 yphH Escherichia coli UTI89 hypothetical protein YP_541860.1 2824724 D 364106 CDS YP_541861.1 91211875 3990208 complement(2825981..2827240) 1 NC_007946.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2827240 glyA 3990208 glyA Escherichia coli UTI89 serine hydroxymethyltransferase YP_541861.1 2825981 R 364106 CDS YP_541862.1 91211876 3990209 2827563..2828753 1 NC_007946.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2828753 hmpA 3990209 hmpA Escherichia coli UTI89 nitric oxide dioxygenase YP_541862.1 2827563 D 364106 CDS YP_541863.1 91211877 3989783 complement(2828798..2829136) 1 NC_007946.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2829136 glnB 3989783 glnB Escherichia coli UTI89 nitrogen regulatory protein P-II 1 YP_541863.1 2828798 R 364106 CDS YP_541864.1 91211878 3989784 complement(2829197..2830570) 1 NC_007946.1 hypothetical protein 2830570 yfhA 3989784 yfhA Escherichia coli UTI89 hypothetical protein YP_541864.1 2829197 R 364106 CDS YP_541865.1 91211879 3989785 complement(2830521..2831240) 1 NC_007946.1 hypothetical protein 2831240 yfhG 3989785 yfhG Escherichia coli UTI89 hypothetical protein YP_541865.1 2830521 R 364106 CDS YP_541866.1 91211880 3989786 2831177..2831332 1 NC_007946.1 hypothetical protein 2831332 3989786 UTI89_C2875 Escherichia coli UTI89 hypothetical protein YP_541866.1 2831177 D 364106 CDS YP_541867.1 91211881 3989787 complement(2831399..2832889) 1 NC_007946.1 sensor-like histidine kinase YfhK 2832889 yfhK 3989787 yfhK Escherichia coli UTI89 sensor-like histidine kinase YfhK YP_541867.1 2831399 R 364106 CDS YP_541868.1 91211882 3989788 complement(2833402..2837445) 1 NC_007946.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2837445 purL 3989788 purL Escherichia coli UTI89 phosphoribosylformylglycinamidine synthase YP_541868.1 2833402 R 364106 CDS YP_541869.1 91211883 3989789 2837548..2839104 1 NC_007946.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2839104 yfhD 3989789 yfhD Escherichia coli UTI89 transglycosylase YP_541869.1 2837548 D 364106 CDS YP_541870.1 91211884 3989790 complement(2839101..2839637) 1 NC_007946.1 tRNA-specific adenosine deaminase 2839637 yfhC 3989790 yfhC Escherichia coli UTI89 tRNA-specific adenosine deaminase YP_541870.1 2839101 R 364106 CDS YP_541871.1 91211885 3989791 complement(2839662..2840297) 1 NC_007946.1 hypothetical protein 2840297 3989791 UTI89_C2880 Escherichia coli UTI89 hypothetical protein YP_541871.1 2839662 R 364106 CDS YP_541872.2 162138389 3989792 2840506..2841354 1 NC_007946.1 DNA-binding transcriptional regulator 2841354 yfhH 3989792 yfhH Escherichia coli UTI89 DNA-binding transcriptional regulator YP_541872.2 2840506 D 364106 CDS YP_541873.1 91211887 3989793 2841410..2841670 1 NC_007946.1 ferredoxin-like protein YfhL 2841670 yfhL 3989793 yfhL Escherichia coli UTI89 ferredoxin-like protein YfhL YP_541873.1 2841410 D 364106 CDS YP_541874.1 91211888 3989794 complement(2841941..2842093) 1 NC_007946.1 hypothetical protein 2842093 3989794 UTI89_C2883 Escherichia coli UTI89 hypothetical protein YP_541874.1 2841941 R 364106 CDS YP_541875.1 91211889 3989795 complement(2842365..2842745) 1 NC_007946.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2842745 acpS 3989795 acpS Escherichia coli UTI89 4'-phosphopantetheinyl transferase YP_541875.1 2842365 R 364106 CDS YP_541876.1 91211890 3989796 complement(2842745..2843491) 1 NC_007946.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2843491 pdxJ 3989796 pdxJ Escherichia coli UTI89 pyridoxine 5'-phosphate synthase YP_541876.1 2842745 R 364106 CDS YP_541877.1 91211891 3989797 complement(2843488..2844216) 1 NC_007946.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2844216 recO 3989797 recO Escherichia coli UTI89 DNA repair protein RecO YP_541877.1 2843488 R 364106 CDS YP_541878.1 91211892 3989798 complement(2844228..2845133) 1 NC_007946.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2845133 era 3989798 era Escherichia coli UTI89 GTP-binding protein Era YP_541878.1 2844228 R 364106 CDS YP_541879.1 91211893 3989799 complement(2845130..2845810) 1 NC_007946.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2845810 rnc 3989799 rnc Escherichia coli UTI89 ribonuclease III YP_541879.1 2845130 R 364106 CDS YP_541880.1 91211894 3989800 2845868..2846026 1 NC_007946.1 hypothetical protein 2846026 3989800 UTI89_C2889 Escherichia coli UTI89 hypothetical protein YP_541880.1 2845868 D 364106 CDS YP_541881.1 91211895 3989801 complement(2846077..2847051) 1 NC_007946.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2847051 lepB 3989801 lepB Escherichia coli UTI89 signal peptidase I YP_541881.1 2846077 R 364106 CDS YP_541882.1 91211896 3989802 complement(2847067..2848866) 1 NC_007946.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2848866 lepA 3989802 lepA Escherichia coli UTI89 GTP-binding protein LepA YP_541882.1 2847067 R 364106 CDS YP_541883.1 91211897 3992200 complement(2849064..2849543) 1 NC_007946.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2849543 rseC 3992200 rseC Escherichia coli UTI89 SoxR reducing system protein RseC YP_541883.1 2849064 R 364106 CDS YP_541884.1 91211898 3992201 complement(2849540..2850496) 1 NC_007946.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2850496 rseB 3992201 rseB Escherichia coli UTI89 periplasmic negative regulator of sigmaE YP_541884.1 2849540 R 364106 CDS YP_541885.1 91211899 3992202 complement(2850496..2851146) 1 NC_007946.1 anti-RNA polymerase sigma factor SigE 2851146 rseA 3992202 rseA Escherichia coli UTI89 anti-RNA polymerase sigma factor SigE YP_541885.1 2850496 R 364106 CDS YP_541886.1 91211900 3992203 complement(2851179..2851787) 1 NC_007946.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2851787 rpoE 3992203 rpoE Escherichia coli UTI89 RNA polymerase sigma factor RpoE YP_541886.1 2851179 R 364106 CDS YP_541887.1 91211901 3992204 2852162..2853784 1 NC_007946.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2853784 nadB 3992204 nadB Escherichia coli UTI89 L-aspartate oxidase YP_541887.1 2852162 D 364106 CDS YP_541888.1 91211902 3992205 complement(2853769..2854626) 1 NC_007946.1 hypothetical protein 2854626 yfiC 3992205 yfiC Escherichia coli UTI89 hypothetical protein YP_541888.1 2853769 R 364106 CDS YP_541889.1 91211903 3992206 2854638..2855972 1 NC_007946.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2855972 3992206 UTI89_C2898 Escherichia coli UTI89 ATP-dependent RNA helicase SrmB YP_541889.1 2854638 D 364106 CDS YP_541890.1 91211904 3992207 complement(2856005..2856931) 1 NC_007946.1 transcriptional regulator YfiE 2856931 yfiE 3992207 yfiE Escherichia coli UTI89 transcriptional regulator YfiE YP_541890.1 2856005 R 364106 CDS YP_541891.1 91211905 3992208 2856989..2857576 1 NC_007946.1 neutral amino-acid efflux protein 2857576 yfiK 3992208 yfiK Escherichia coli UTI89 neutral amino-acid efflux protein YP_541891.1 2856989 D 364106 CDS YP_541892.2 162138388 3992209 complement(2857632..2858015) 1 NC_007946.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2858015 yfiD 3992209 yfiD Escherichia coli UTI89 autonomous glycyl radical cofactor GrcA YP_541892.2 2857632 R 364106 CDS YP_541893.1 91211907 3992210 2858320..2859009 1 NC_007946.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2859009 ung 3992210 ung Escherichia coli UTI89 uracil-DNA glycosylase YP_541893.1 2858320 D 364106 CDS YP_541894.1 91211908 3992211 complement(2859057..2860169) 1 NC_007946.1 methyltransferase 2860169 yfiF 3992211 yfiF Escherichia coli UTI89 methyltransferase YP_541894.1 2859057 R 364106 CDS YP_541895.1 91211909 3992212 complement(2860084..2860287) 1 NC_007946.1 hypothetical protein 2860287 3992212 UTI89_C2904 Escherichia coli UTI89 hypothetical protein YP_541895.1 2860084 R 364106 CDS YP_541896.1 91211910 3992213 2860301..2860720 1 NC_007946.1 thioredoxin 2860720 trxC 3992213 trxC Escherichia coli UTI89 thioredoxin YP_541896.1 2860301 D 364106 CDS YP_541897.1 91211911 3992214 2860738..2861487 1 NC_007946.1 hypothetical protein 2861487 yfiP 3992214 yfiP Escherichia coli UTI89 hypothetical protein YP_541897.1 2860738 D 364106 CDS YP_541898.1 91211912 3992215 2861519..2864179 1 NC_007946.1 hypothetical protein 2864179 yfiQ 3992215 yfiQ Escherichia coli UTI89 hypothetical protein YP_541898.1 2861519 D 364106 CDS YP_541899.1 91211913 3992216 2864290..2865648 1 NC_007946.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2865648 pssA 3992216 pssA Escherichia coli UTI89 phosphatidylserine synthase YP_541899.1 2864290 D 364106 CDS YP_541900.1 91211914 3992217 2865673..2866017 1 NC_007946.1 hypothetical protein 2866017 yfiM 3992217 yfiM Escherichia coli UTI89 hypothetical protein YP_541900.1 2865673 D 364106 CDS YP_541901.1 91211915 3992218 complement(2866014..2867405) 1 NC_007946.1 alpha-ketoglutarate transporter 2867405 kgtP 3992218 kgtP Escherichia coli UTI89 alpha-ketoglutarate transporter YP_541901.1 2866014 R 364106 CDS YP_541902.1 91211916 3992219 2867421..2867681 1 NC_007946.1 hypothetical protein 2867681 3992219 UTI89_C2911 Escherichia coli UTI89 hypothetical protein YP_541902.1 2867421 D 364106 CDS YP_541903.1 91211917 3992220 2867822..2868346 1 NC_007946.1 hypothetical protein 2868346 3992220 UTI89_C2912 Escherichia coli UTI89 hypothetical protein YP_541903.1 2867822 D 364106 CDS YP_541904.1 91211918 3992221 complement(2868217..2868621) 1 NC_007946.1 IS621-Tnp; transposase 2868621 3992221 UTI89_C2913 Escherichia coli UTI89 transposase YP_541904.1 2868217 R 364106 CDS YP_541905.1 91211919 3992222 2868472..2868840 1 NC_007946.1 hypothetical protein 2868840 3992222 UTI89_C2914 Escherichia coli UTI89 hypothetical protein YP_541905.1 2868472 D 364106 CDS YP_541906.1 91211920 3992223 complement(2868865..2869587) 1 NC_007946.1 transposase InsK for insertion sequence element IS150 2869587 3992223 UTI89_C2915 Escherichia coli UTI89 transposase InsK for insertion sequence element IS150 YP_541906.1 2868865 R 364106 CDS YP_541911.1 91211925 3992232 2875418..2875666 1 NC_007946.1 hypothetical protein 2875666 3992232 UTI89_C2924 Escherichia coli UTI89 hypothetical protein YP_541911.1 2875418 D 364106 CDS YP_541912.1 91211926 3992233 complement(2875801..2878386) 1 NC_007946.1 protein disaggregation chaperone 2878386 clpB 3992233 clpB Escherichia coli UTI89 protein disaggregation chaperone YP_541912.1 2875801 R 364106 CDS YP_541913.1 91211927 3992234 complement(2878504..2879235) 1 NC_007946.1 hypothetical protein 2879235 yfiH 3992234 yfiH Escherichia coli UTI89 hypothetical protein YP_541913.1 2878504 R 364106 CDS YP_541914.1 91211928 3992332 complement(2879232..2880212) 1 NC_007946.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2880212 rluD 3992332 rluD Escherichia coli UTI89 23S rRNA pseudouridine synthase D YP_541914.1 2879232 R 364106 CDS YP_541915.1 91211929 3992333 2880347..2881084 1 NC_007946.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2881084 3992333 UTI89_C2928 Escherichia coli UTI89 outer membrane protein assembly complex subunit YfiO YP_541915.1 2880347 D 364106 CDS YP_541916.1 91211930 3992334 2881113..2881319 1 NC_007946.1 hypothetical protein 2881319 3992334 UTI89_C2929 Escherichia coli UTI89 hypothetical protein YP_541916.1 2881113 D 364106 CDS YP_541917.1 91211931 3992335 complement(2881273..2881809) 1 NC_007946.1 hypothetical protein 2881809 3992335 UTI89_C2930 Escherichia coli UTI89 hypothetical protein YP_541917.1 2881273 R 364106 CDS YP_541918.1 91211932 3992336 2881354..2881695 1 NC_007946.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2881695 3992336 UTI89_C2931 Escherichia coli UTI89 translation inhibitor protein RaiA YP_541918.1 2881354 D 364106 CDS YP_541919.1 91211933 3992337 2881945..2883105 1 NC_007946.1 bifunctional P protein; catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2883105 pheA 3992337 pheA Escherichia coli UTI89 bifunctional chorismate mutase/prephenate dehydratase YP_541919.1 2881945 D 364106 CDS YP_541920.1 91211934 3992338 complement(2883148..2884269) 1 NC_007946.1 bifunctional T protein; catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 2884269 tyrA 3992338 tyrA Escherichia coli UTI89 bifunctional chorismate mutase/prephenate dehydrogenase YP_541920.1 2883148 R 364106 CDS YP_541921.1 91211935 3992339 complement(2884280..2885419) 1 NC_007946.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2885419 aroF 3992339 aroF Escherichia coli UTI89 phospho-2-dehydro-3-deoxyheptonate aldolase YP_541921.1 2884280 R 364106 CDS YP_541922.1 91211936 3992340 2885542..2885925 1 NC_007946.1 hypothetical protein 2885925 yfiL 3992340 yfiL Escherichia coli UTI89 hypothetical protein YP_541922.1 2885542 D 364106 CDS YP_541923.1 91211937 3992341 2886074..2886592 1 NC_007946.1 hypothetical protein 2886592 yfiR 3992341 yfiR Escherichia coli UTI89 hypothetical protein YP_541923.1 2886074 D 364106 CDS YP_541924.1 91211938 3992342 2886582..2887808 1 NC_007946.1 hypothetical protein 2887808 yfiN 3992342 yfiN Escherichia coli UTI89 hypothetical protein YP_541924.1 2886582 D 364106 CDS YP_541925.1 91211939 3992343 2887824..2888306 1 NC_007946.1 outer membrane lipoprotein 2888306 yfiB 3992343 yfiB Escherichia coli UTI89 outer membrane lipoprotein YP_541925.1 2887824 D 364106 CDS YP_541926.1 91211940 3992344 complement(2888383..2888730) 1 NC_007946.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2888730 rplS 3992344 rplS Escherichia coli UTI89 50S ribosomal protein L19 YP_541926.1 2888383 R 364106 CDS YP_541927.1 91211941 3992345 complement(2888772..2889539) 1 NC_007946.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 2889539 trmD 3992345 trmD Escherichia coli UTI89 tRNA (guanine-N(1)-)-methyltransferase YP_541927.1 2888772 R 364106 CDS YP_541928.1 91211942 3992346 complement(2889570..2890127) 1 NC_007946.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2890127 rimM 3992346 rimM Escherichia coli UTI89 16S rRNA-processing protein RimM YP_541928.1 2889570 R 364106 CDS YP_541929.2 162138387 3992347 complement(2890137..2890385) 1 NC_007946.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2890385 rpsP 3992347 rpsP Escherichia coli UTI89 30S ribosomal protein S16 YP_541929.2 2890137 R 364106 CDS YP_541930.1 91211944 3992348 complement(2890522..2891883) 1 NC_007946.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 2891883 ffh 3992348 ffh Escherichia coli UTI89 signal recognition particle protein YP_541930.1 2890522 R 364106 CDS YP_541931.1 91211945 3992349 2891975..2892841 1 NC_007946.1 hypothetical protein 2892841 ypjD 3992349 ypjD Escherichia coli UTI89 hypothetical protein YP_541931.1 2891975 D 364106 CDS YP_541932.2 162138386 3992350 2892952..2894148 1 NC_007946.1 hypothetical protein 2894148 yfjD 3992350 yfjD Escherichia coli UTI89 hypothetical protein YP_541932.2 2892952 D 364106 CDS YP_541933.1 91211947 3992351 2894170..2894922 1 NC_007946.1 hypothetical protein 2894922 3992351 UTI89_C2946 Escherichia coli UTI89 hypothetical protein YP_541933.1 2894170 D 364106 CDS YP_541934.1 91211948 3992970 complement(2894203..2894796) 1 NC_007946.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2894796 grpE 3992970 grpE Escherichia coli UTI89 heat shock protein GrpE YP_541934.1 2894203 R 364106 CDS YP_541935.1 91211949 3992971 complement(2894793..2895044) 1 NC_007946.1 hypothetical protein 2895044 yfjC 3992971 yfjC Escherichia coli UTI89 hypothetical protein YP_541935.1 2894793 R 364106 CDS YP_541936.1 91211950 3992972 2894919..2895797 1 NC_007946.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2895797 ppnK 3992972 ppnK Escherichia coli UTI89 inorganic polyphosphate/ATP-NAD kinase YP_541936.1 2894919 D 364106 CDS YP_541937.1 91211951 3992973 2895883..2897544 1 NC_007946.1 recombination and repair protein 2897544 recN 3992973 recN Escherichia coli UTI89 recombination and repair protein YP_541937.1 2895883 D 364106 CDS YP_541938.1 91211952 3992974 2897693..2898034 1 NC_007946.1 hypothetical protein 2898034 smpA 3992974 smpA Escherichia coli UTI89 hypothetical protein YP_541938.1 2897693 D 364106 CDS YP_541939.1 91211953 3992975 complement(2898096..2898404) 1 NC_007946.1 hypothetical protein 2898404 yfjF 3992975 yfjF Escherichia coli UTI89 hypothetical protein YP_541939.1 2898096 R 364106 CDS YP_541940.1 91211954 3992976 complement(2898376..2898852) 1 NC_007946.1 hypothetical protein 2898852 yfjG 3992976 yfjG Escherichia coli UTI89 hypothetical protein YP_541940.1 2898376 R 364106 CDS YP_541941.1 91211955 3992977 2898984..2899466 1 NC_007946.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2899466 smpB 3992977 smpB Escherichia coli UTI89 SsrA-binding protein YP_541941.1 2898984 D 364106 CDS YP_541942.1 91211956 3992978 complement(2900045..2900299) 1 NC_007946.1 hypothetical protein 2900299 3992978 UTI89_C2955 Escherichia coli UTI89 hypothetical protein YP_541942.1 2900045 R 364106 CDS YP_541943.1 91211957 3992979 2900429..2900626 1 NC_007946.1 hypothetical protein 2900626 3992979 UTI89_C2956 Escherichia coli UTI89 hypothetical protein YP_541943.1 2900429 D 364106 CDS YP_541944.1 91211958 3992980 2900623..2901411 1 NC_007946.1 hypothetical protein 2901411 3992980 UTI89_C2957 Escherichia coli UTI89 hypothetical protein YP_541944.1 2900623 D 364106 CDS YP_541945.1 91211959 3992981 complement(2901499..2901792) 1 NC_007946.1 hypothetical protein 2901792 3992981 UTI89_C2958 Escherichia coli UTI89 hypothetical protein YP_541945.1 2901499 R 364106 CDS YP_541946.1 91211960 3992982 complement(2902003..2902776) 1 NC_007946.1 prophage CP-933H hypothetical protein 2902776 3992982 UTI89_C2959 Escherichia coli UTI89 prophage CP-933H hypothetical protein YP_541946.1 2902003 R 364106 CDS YP_541947.1 91211961 3992983 2903828..2905717 1 NC_007946.1 hypothetical protein 2905717 3992983 UTI89_C2960 Escherichia coli UTI89 hypothetical protein YP_541947.1 2903828 D 364106 CDS YP_541948.1 91211962 3992984 2906465..2906908 1 NC_007946.1 hypothetical protein 2906908 yfdK 3992984 yfdK Escherichia coli UTI89 hypothetical protein YP_541948.1 2906465 D 364106 CDS YP_541949.1 91211963 3992985 complement(2906880..2907482) 1 NC_007946.1 lambdoid prophage e14 tail fiber assembly protein-like protein 2907482 tfaE 3992985 tfaE Escherichia coli UTI89 lambdoid prophage e14 tail fiber assembly protein-like protein YP_541949.1 2906880 R 364106 CDS YP_541950.1 91211964 3992986 complement(2907482..2908225) 1 NC_007946.1 hypothetical protein 2908225 ycfK 3992986 ycfK Escherichia coli UTI89 hypothetical protein YP_541950.1 2907482 R 364106 CDS YP_541951.1 91211965 3992987 complement(2908229..2908813) 1 NC_007946.1 bacteriophage V tail protein 2908813 3992987 UTI89_C2964 Escherichia coli UTI89 bacteriophage V tail protein YP_541951.1 2908229 R 364106 CDS YP_541952.1 91211966 3992524 complement(2908804..2909862) 1 NC_007946.1 bacteriophage V tail protein 2909862 3992524 UTI89_C2965 Escherichia coli UTI89 bacteriophage V tail protein YP_541952.1 2908804 R 364106 CDS YP_541953.1 91211967 3992525 complement(2909849..2910274) 1 NC_007946.1 bacteriophage V tail protein 2910274 3992525 UTI89_C2966 Escherichia coli UTI89 bacteriophage V tail protein YP_541953.1 2909849 R 364106 CDS YP_541954.1 91211968 3992526 complement(2910274..2910822) 1 NC_007946.1 bacteriophage V tail protein 2910822 3992526 UTI89_C2967 Escherichia coli UTI89 bacteriophage V tail protein YP_541954.1 2910274 R 364106 CDS YP_541955.1 91211969 3992527 complement(2910822..2911901) 1 NC_007946.1 bacteriophage V tail protein 2911901 3992527 UTI89_C2968 Escherichia coli UTI89 bacteriophage V tail protein YP_541955.1 2910822 R 364106 CDS YP_541956.1 91211970 3992528 complement(2911898..2913253) 1 NC_007946.1 bacteriophage V tail/DNA circulation protein 2913253 3992528 UTI89_C2969 Escherichia coli UTI89 bacteriophage V tail/DNA circulation protein YP_541956.1 2911898 R 364106 CDS YP_541957.1 91211971 3992529 complement(2913287..2915122) 1 NC_007946.1 bacteriophage V tail protein 2915122 3992529 UTI89_C2970 Escherichia coli UTI89 bacteriophage V tail protein YP_541957.1 2913287 R 364106 CDS YP_541958.1 91211972 3992530 complement(2915264..2915533) 1 NC_007946.1 hypothetical protein 2915533 3992530 UTI89_C2971 Escherichia coli UTI89 hypothetical protein YP_541958.1 2915264 R 364106 CDS YP_541959.1 91211973 3992531 complement(2915533..2915889) 1 NC_007946.1 hypothetical protein 2915889 3992531 UTI89_C2972 Escherichia coli UTI89 hypothetical protein YP_541959.1 2915533 R 364106 CDS YP_541960.1 91211974 3992532 complement(2915889..2917385) 1 NC_007946.1 bacteriophage V tail sheath protein 2917385 3992532 UTI89_C2973 Escherichia coli UTI89 bacteriophage V tail sheath protein YP_541960.1 2915889 R 364106 CDS YP_541961.1 91211975 3992533 complement(2917369..2917539) 1 NC_007946.1 hypothetical protein 2917539 3992533 UTI89_C2974 Escherichia coli UTI89 hypothetical protein YP_541961.1 2917369 R 364106 CDS YP_541962.1 91211976 3992534 complement(2917548..2918108) 1 NC_007946.1 hypothetical protein 2918108 3992534 UTI89_C2975 Escherichia coli UTI89 hypothetical protein YP_541962.1 2917548 R 364106 CDS YP_541963.1 91211977 3992535 complement(2918105..2918611) 1 NC_007946.1 hypothetical protein 2918611 3992535 UTI89_C2976 Escherichia coli UTI89 hypothetical protein YP_541963.1 2918105 R 364106 CDS YP_541964.1 91211978 3992536 complement(2918586..2918996) 1 NC_007946.1 hypothetical protein 2918996 3992536 UTI89_C2977 Escherichia coli UTI89 hypothetical protein YP_541964.1 2918586 R 364106 CDS YP_541965.1 91211979 3992537 2918622..2919089 1 NC_007946.1 hypothetical protein 2919089 3992537 UTI89_C2978 Escherichia coli UTI89 hypothetical protein YP_541965.1 2918622 D 364106 CDS YP_541966.1 91211980 3992538 complement(2918993..2919316) 1 NC_007946.1 hypothetical protein 2919316 3992538 UTI89_C2979 Escherichia coli UTI89 hypothetical protein YP_541966.1 2918993 R 364106 CDS YP_541967.1 91211981 3992539 complement(2919319..2919519) 1 NC_007946.1 hypothetical protein 2919519 3992539 UTI89_C2980 Escherichia coli UTI89 hypothetical protein YP_541967.1 2919319 R 364106 CDS YP_541968.1 91211982 3992540 complement(2919569..2920774) 1 NC_007946.1 major capsid protein 2920774 3992540 UTI89_C2981 Escherichia coli UTI89 major capsid protein YP_541968.1 2919569 R 364106 CDS YP_541969.1 91211983 3992541 complement(2920789..2921475) 1 NC_007946.1 pro-head protease 2921475 3992541 UTI89_C2982 Escherichia coli UTI89 pro-head protease YP_541969.1 2920789 R 364106 CDS YP_541970.1 91211984 3992542 complement(2921417..2922658) 1 NC_007946.1 portal protein 2922658 3992542 UTI89_C2983 Escherichia coli UTI89 portal protein YP_541970.1 2921417 R 364106 CDS YP_541971.1 91211985 3992543 complement(2922658..2922840) 1 NC_007946.1 hypothetical protein 2922840 ymfR 3992543 ymfR Escherichia coli UTI89 hypothetical protein YP_541971.1 2922658 R 364106 CDS YP_541972.1 91211986 3993044 complement(2922852..2924585) 1 NC_007946.1 bacteriophage V large terminase subunit 2924585 3993044 UTI89_C2985 Escherichia coli UTI89 bacteriophage V large terminase subunit YP_541972.1 2922852 R 364106 CDS YP_541973.1 91211987 3993045 complement(2924582..2925076) 1 NC_007946.1 bacteriophage V small terminase subunit 2925076 3993045 UTI89_C2986 Escherichia coli UTI89 bacteriophage V small terminase subunit YP_541973.1 2924582 R 364106 CDS YP_541974.1 91211988 3993046 complement(2925202..2925552) 1 NC_007946.1 hypothetical protein 2925552 3993046 UTI89_C2987 Escherichia coli UTI89 hypothetical protein YP_541974.1 2925202 R 364106 CDS YP_541975.1 91211989 3993047 complement(2926201..2926449) 1 NC_007946.1 hypothetical protein 2926449 3993047 UTI89_C2988 Escherichia coli UTI89 hypothetical protein YP_541975.1 2926201 R 364106 CDS YP_541976.1 91211990 3993048 complement(2926523..2926960) 1 NC_007946.1 hypothetical protein 2926960 3993048 UTI89_C2989 Escherichia coli UTI89 hypothetical protein YP_541976.1 2926523 R 364106 CDS YP_541977.1 91211991 3993049 complement(2926957..2927433) 1 NC_007946.1 endolysin of prophage CP-933X 2927433 3993049 UTI89_C2990 Escherichia coli UTI89 endolysin of prophage CP-933X YP_541977.1 2926957 R 364106 CDS YP_541978.1 91211992 3993050 complement(2927420..2927725) 1 NC_007946.1 holin protein of prophage CP-933X 2927725 3993050 UTI89_C2991 Escherichia coli UTI89 holin protein of prophage CP-933X YP_541978.1 2927420 R 364106 CDS YP_541979.1 91211993 3993051 complement(2927877..2928212) 1 NC_007946.1 hypothetical protein 2928212 3993051 UTI89_C2992 Escherichia coli UTI89 hypothetical protein YP_541979.1 2927877 R 364106 CDS YP_541980.1 91211994 3993052 complement(2928398..2929180) 1 NC_007946.1 lambdoid prophage Qin antitermination protein Q-like protein 2929180 3993052 UTI89_C2993 Escherichia coli UTI89 lambdoid prophage Qin antitermination protein Q-like protein YP_541980.1 2928398 R 364106 CDS YP_541981.1 91211995 3993053 complement(2929164..2930159) 1 NC_007946.1 hypothetical protein 2930159 ydfU1 3993053 ydfU1 Escherichia coli UTI89 hypothetical protein YP_541981.1 2929164 R 364106 CDS YP_541982.1 91211996 3993054 complement(2930161..2930958) 1 NC_007946.1 hypothetical protein 2930958 3993054 UTI89_C2995 Escherichia coli UTI89 hypothetical protein YP_541982.1 2930161 R 364106 CDS YP_541983.1 91211997 3993055 complement(2930978..2931367) 1 NC_007946.1 bacteriophage V crossover junction endodeoxyribonuclease 2931367 3993055 UTI89_C2996 Escherichia coli UTI89 bacteriophage V crossover junction endodeoxyribonuclease YP_541983.1 2930978 R 364106 CDS YP_541984.1 91211998 3993056 complement(2931364..2931690) 1 NC_007946.1 hypothetical protein 2931690 3993056 UTI89_C2997 Escherichia coli UTI89 hypothetical protein YP_541984.1 2931364 R 364106 CDS YP_541985.1 91211999 3993057 complement(2931687..2932340) 1 NC_007946.1 bacteriophage V DNA adenine methylase 2932340 3993057 UTI89_C2998 Escherichia coli UTI89 bacteriophage V DNA adenine methylase YP_541985.1 2931687 R 364106 CDS YP_541986.1 91212000 3993058 complement(2932340..2932834) 1 NC_007946.1 hypothetical protein 2932834 yfdN1 3993058 yfdN1 Escherichia coli UTI89 hypothetical protein YP_541986.1 2932340 R 364106 CDS YP_541987.1 91212001 3993059 complement(2932831..2933772) 1 NC_007946.1 hypothetical protein 2933772 3993059 UTI89_C3000 Escherichia coli UTI89 hypothetical protein YP_541987.1 2932831 R 364106 CDS YP_541988.1 91212002 3993060 complement(2933782..2934120) 1 NC_007946.1 hypothetical protein 2934120 ymfM 3993060 ymfM Escherichia coli UTI89 hypothetical protein YP_541988.1 2933782 R 364106 CDS YP_541989.1 91212003 3993061 complement(2934117..2934680) 1 NC_007946.1 hypothetical protein 2934680 ymfL 3993061 ymfL Escherichia coli UTI89 hypothetical protein YP_541989.1 2934117 R 364106 CDS YP_541990.1 91212004 3993062 complement(2934712..2935215) 1 NC_007946.1 hypothetical protein 2935215 3993062 UTI89_C3003 Escherichia coli UTI89 hypothetical protein YP_541990.1 2934712 R 364106 CDS YP_541991.1 91212005 3992834 2935003..2935677 1 NC_007946.1 phage repressor 2935677 ymfK 3992834 ymfK Escherichia coli UTI89 phage repressor YP_541991.1 2935003 D 364106 CDS YP_541992.1 91212006 3992835 complement(2935880..2936392) 1 NC_007946.1 hypothetical protein 2936392 3992835 UTI89_C3005 Escherichia coli UTI89 hypothetical protein YP_541992.1 2935880 R 364106 CDS YP_541993.1 91212007 3992836 2937289..2938113 1 NC_007946.1 hypothetical protein 2938113 yfdQ1 3992836 yfdQ1 Escherichia coli UTI89 hypothetical protein YP_541993.1 2937289 D 364106 CDS YP_541994.1 91212008 3992837 2938214..2938765 1 NC_007946.1 hypothetical protein 2938765 yfdR1 3992837 yfdR1 Escherichia coli UTI89 hypothetical protein YP_541994.1 2938214 D 364106 CDS YP_541995.1 91212009 3992838 2938850..2939740 1 NC_007946.1 hypothetical protein 2939740 3992838 UTI89_C3008 Escherichia coli UTI89 hypothetical protein YP_541995.1 2938850 D 364106 CDS YP_541996.1 91212010 3992839 2939949..2941121 1 NC_007946.1 hypothetical protein 2941121 3992839 UTI89_C3009 Escherichia coli UTI89 hypothetical protein YP_541996.1 2939949 D 364106 CDS YP_541997.1 91212011 3992840 complement(2941113..2941712) 1 NC_007946.1 hypothetical protein 2941712 3992840 UTI89_C3010 Escherichia coli UTI89 hypothetical protein YP_541997.1 2941113 R 364106 CDS YP_541998.1 91212012 3992841 complement(2941741..2942067) 1 NC_007946.1 hypothetical protein 2942067 3992841 UTI89_C3011 Escherichia coli UTI89 hypothetical protein YP_541998.1 2941741 R 364106 CDS YP_541999.1 91212013 3992842 complement(2942072..2942983) 1 NC_007946.1 hypothetical protein 2942983 3992842 UTI89_C3012 Escherichia coli UTI89 hypothetical protein YP_541999.1 2942072 R 364106 CDS YP_542000.1 91212014 3992843 2942958..2943212 1 NC_007946.1 hypothetical protein 2943212 3992843 UTI89_C3013 Escherichia coli UTI89 hypothetical protein YP_542000.1 2942958 D 364106 CDS YP_542001.1 91212015 3992844 2943844..2944821 1 NC_007946.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2944821 ygaT 3992844 ygaT Escherichia coli UTI89 hypothetical protein YP_542001.1 2943844 D 364106 CDS YP_542002.1 91212016 3992845 2944775..2946109 1 NC_007946.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2946109 ygaF 3992845 ygaF Escherichia coli UTI89 hydroxyglutarate oxidase YP_542002.1 2944775 D 364106 CDS YP_542003.1 91212017 3992846 2946132..2947580 1 NC_007946.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2947580 gabD 3992846 gabD Escherichia coli UTI89 succinate-semialdehyde dehydrogenase I YP_542003.1 2946132 D 364106 CDS YP_542004.1 91212018 3992847 2947588..2948874 1 NC_007946.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2948874 gabT 3992847 gabT Escherichia coli UTI89 4-aminobutyrate aminotransferase YP_542004.1 2947588 D 364106 CDS YP_542005.2 162138385 3992848 2949112..2950512 1 NC_007946.1 gamma-aminobutyrate transporter 2950512 gabP 3992848 gabP Escherichia coli UTI89 gamma-aminobutyrate transporter YP_542005.2 2949112 D 364106 CDS YP_542006.2 162138384 3992849 2950533..2951195 1 NC_007946.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2951195 ygaE 3992849 ygaE Escherichia coli UTI89 DNA-binding transcriptional regulator CsiR YP_542006.2 2950533 D 364106 CDS YP_542007.1 91212021 3992850 complement(2951196..2951645) 1 NC_007946.1 LysM domain/BON superfamily protein 2951645 ygaU 3992850 ygaU Escherichia coli UTI89 LysM domain/BON superfamily protein YP_542007.1 2951196 R 364106 CDS YP_542008.1 91212022 3992851 2951717..2951902 1 NC_007946.1 hypothetical protein 2951902 3992851 UTI89_C3021 Escherichia coli UTI89 hypothetical protein YP_542008.1 2951717 D 364106 CDS YP_542009.1 91212023 3992852 complement(2951729..2951887) 1 NC_007946.1 hypothetical protein 2951887 yqaE 3992852 yqaE Escherichia coli UTI89 hypothetical protein YP_542009.1 2951729 R 364106 CDS YP_542010.1 91212024 3992853 2952070..2952369 1 NC_007946.1 transcriptional regulator 2952369 ygaV 3992853 ygaV Escherichia coli UTI89 transcriptional regulator YP_542010.1 2952070 D 364106 CDS YP_542011.1 91212025 3993007 2952379..2952903 1 NC_007946.1 hypothetical protein 2952903 ygaP 3993007 ygaP Escherichia coli UTI89 hypothetical protein YP_542011.1 2952379 D 364106 CDS YP_542012.1 91212026 3993008 complement(2952950..2953354) 1 NC_007946.1 DNA binding protein, nucleoid-associated 2953354 stpA 3993008 stpA Escherichia coli UTI89 DNA binding protein, nucleoid-associated YP_542012.1 2952950 R 364106 CDS YP_542013.1 91212027 3993009 2953768..2953896 1 NC_007946.1 hypothetical protein 2953896 3993009 UTI89_C3026 Escherichia coli UTI89 hypothetical protein YP_542013.1 2953768 D 364106 CDS YP_542014.1 91212028 3993010 2954022..2954471 1 NC_007946.1 hypothetical protein 2954471 ygaW 3993010 ygaW Escherichia coli UTI89 hypothetical protein YP_542014.1 2954022 D 364106 CDS YP_542015.1 91212029 3993011 complement(2954508..2954852) 1 NC_007946.1 hypothetical protein 2954852 ygaC 3993011 ygaC Escherichia coli UTI89 hypothetical protein YP_542015.1 2954508 R 364106 CDS YP_542016.1 91212030 3993012 2954992..2955333 1 NC_007946.1 hypothetical protein 2955333 ygaM 3993012 ygaM Escherichia coli UTI89 hypothetical protein YP_542016.1 2954992 D 364106 CDS YP_542017.1 91212031 3993013 complement(2955390..2956724) 1 NC_007946.1 hypothetical protein 2956724 3993013 UTI89_C3030 Escherichia coli UTI89 hypothetical protein YP_542017.1 2955390 R 364106 CDS YP_542018.1 91212032 3993014 2956812..2957243 1 NC_007946.1 hypothetical protein 2957243 3993014 UTI89_C3031 Escherichia coli UTI89 hypothetical protein YP_542018.1 2956812 D 364106 CDS YP_542019.1 91212033 3993015 complement(2957428..2957682) 1 NC_007946.1 hypothetical protein 2957682 3993015 UTI89_C3032 Escherichia coli UTI89 hypothetical protein YP_542019.1 2957428 R 364106 CDS YP_542020.1 91212034 3993016 2957452..2957697 1 NC_007946.1 glutaredoxin-like protein 2957697 nrdH 3993016 nrdH Escherichia coli UTI89 glutaredoxin-like protein YP_542020.1 2957452 D 364106 CDS YP_542021.1 91212035 3993017 2957694..2958104 1 NC_007946.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2958104 nrdI 3993017 nrdI Escherichia coli UTI89 ribonucleotide reductase stimulatory protein YP_542021.1 2957694 D 364106 CDS YP_542022.1 91212036 3993018 2958077..2960221 1 NC_007946.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2960221 nrdE 3993018 nrdE Escherichia coli UTI89 ribonucleotide-diphosphate reductase subunit alpha YP_542022.1 2958077 D 364106 CDS YP_542023.1 91212037 3993019 2960231..2961190 1 NC_007946.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2961190 nrdF 3993019 nrdF Escherichia coli UTI89 ribonucleotide-diphosphate reductase subunit beta YP_542023.1 2960231 D 364106 CDS YP_542024.1 91212038 3993020 2961546..2962748 1 NC_007946.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2962748 proV 3993020 proV Escherichia coli UTI89 glycine betaine transporter ATP-binding subunit YP_542024.1 2961546 D 364106 CDS YP_542025.1 91212039 3993021 2962741..2963805 1 NC_007946.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2963805 proW 3993021 proW Escherichia coli UTI89 glycine betaine transporter membrane protein YP_542025.1 2962741 D 364106 CDS YP_542026.2 162138383 3993022 2963863..2964855 1 NC_007946.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2964855 proX 3993022 proX Escherichia coli UTI89 glycine betaine transporter periplasmic subunit YP_542026.2 2963863 D 364106 CDS YP_542027.1 91212041 3993023 2964908..2965054 1 NC_007946.1 hypothetical protein 2965054 3993023 UTI89_C3040 Escherichia coli UTI89 hypothetical protein YP_542027.1 2964908 D 364106 CDS YP_542028.1 91212042 3993024 2965047..2966231 1 NC_007946.1 transport protein 2966231 ygaY 3993024 ygaY Escherichia coli UTI89 transport protein YP_542028.1 2965047 D 364106 CDS YP_542029.1 91212043 3993025 2966355..2967092 1 NC_007946.1 hypothetical protein 2967092 ygaZ 3993025 ygaZ Escherichia coli UTI89 hypothetical protein YP_542029.1 2966355 D 364106 CDS YP_542030.1 91212044 3990578 2967082..2967417 1 NC_007946.1 hypothetical protein 2967417 ygaH 3990578 ygaH Escherichia coli UTI89 hypothetical protein YP_542030.1 2967082 D 364106 CDS YP_542031.1 91212045 3990579 2967508..2968038 1 NC_007946.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2968038 mprA 3990579 mprA Escherichia coli UTI89 transcriptional repressor MprA YP_542031.1 2967508 D 364106 CDS YP_542032.1 91212046 3990580 2968153..2969337 1 NC_007946.1 multidrug resistance protein A 2969337 emrA 3990580 emrA Escherichia coli UTI89 multidrug resistance protein A YP_542032.1 2968153 D 364106 CDS YP_542033.1 91212047 3990581 2969345..2970892 1 NC_007946.1 multidrug resistance protein B 2970892 emrB 3990581 emrB Escherichia coli UTI89 multidrug resistance protein B YP_542033.1 2969345 D 364106 CDS YP_542034.1 91212048 3990582 2971150..2971857 1 NC_007946.1 hypothetical protein 2971857 3990582 UTI89_C3047 Escherichia coli UTI89 hypothetical protein YP_542034.1 2971150 D 364106 CDS YP_542035.1 91212049 3990583 2971854..2972966 1 NC_007946.1 hypothetical protein 2972966 3990583 UTI89_C3048 Escherichia coli UTI89 hypothetical protein YP_542035.1 2971854 D 364106 CDS YP_542036.1 91212050 3990584 complement(2973017..2973532) 1 NC_007946.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2973532 luxS 3990584 luxS Escherichia coli UTI89 S-ribosylhomocysteinase YP_542036.1 2973017 R 364106 CDS YP_542037.1 91212051 3990585 complement(2973683..2975239) 1 NC_007946.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 2975239 gshA 3990585 gshA Escherichia coli UTI89 glutamate--cysteine ligase YP_542037.1 2973683 R 364106 CDS YP_542038.1 91212052 3990586 complement(2975312..2975740) 1 NC_007946.1 hypothetical protein 2975740 yqaA 3990586 yqaA Escherichia coli UTI89 hypothetical protein YP_542038.1 2975312 R 364106 CDS YP_542039.1 91212053 3990587 complement(2975737..2976303) 1 NC_007946.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 2976303 yqaB 3990587 yqaB Escherichia coli UTI89 fructose-1-phosphatase YP_542039.1 2975737 R 364106 CDS YP_542040.1 91212054 3990592 complement(2977353..2977538) 1 NC_007946.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 2977538 csrA 3990592 csrA Escherichia coli UTI89 carbon storage regulator YP_542040.1 2977353 R 364106 CDS YP_542041.1 91212055 3990210 complement(2977773..2980403) 1 NC_007946.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2980403 alaS 3990210 alaS Escherichia coli UTI89 alanyl-tRNA synthetase YP_542041.1 2977773 R 364106 CDS YP_542042.1 91212056 3990211 2980308..2980490 1 NC_007946.1 hypothetical protein 2980490 3990211 UTI89_C3059 Escherichia coli UTI89 hypothetical protein YP_542042.1 2980308 D 364106 CDS YP_542043.1 91212057 3990212 complement(2980531..2981031) 1 NC_007946.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2981031 recX 3990212 recX Escherichia coli UTI89 recombination regulator RecX YP_542043.1 2980531 R 364106 CDS YP_542044.1 91212058 3990213 complement(2981100..2982161) 1 NC_007946.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2982161 recA 3990213 recA Escherichia coli UTI89 recombinase A YP_542044.1 2981100 R 364106 CDS YP_542045.1 91212059 3990214 complement(2982241..2982741) 1 NC_007946.1 competence damage-inducible protein A 2982741 ygaD 3990214 ygaD Escherichia coli UTI89 competence damage-inducible protein A YP_542045.1 2982241 R 364106 CDS YP_542046.1 91212060 3990215 complement(2982883..2984073) 1 NC_007946.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 2984073 mltB 3990215 mltB Escherichia coli UTI89 murein hydrolase B YP_542046.1 2982883 R 364106 CDS YP_542047.1 91212061 3990216 2984225..2984788 1 NC_007946.1 PTS system glucitol/sorbitol-specific transporter subunit IIC2 2984788 srlA 3990216 srlA Escherichia coli UTI89 PTS system glucitol/sorbitol-specific transporter subunit IIC2 YP_542047.1 2984225 D 364106 CDS YP_542048.1 91212062 3990217 2984785..2985744 1 NC_007946.1 PTS system glucitol-sorbitol-specific transporter subunit IIBC 2985744 srlE 3990217 srlE Escherichia coli UTI89 PTS system glucitol-sorbitol-specific transporter subunit IIBC YP_542048.1 2984785 D 364106 CDS YP_542049.1 91212063 3990218 2985755..2986126 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2986126 srlB 3990218 srlB Escherichia coli UTI89 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_542049.1 2985755 D 364106 CDS YP_542050.1 91212064 3990219 2986130..2986909 1 NC_007946.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2986909 srlD 3990219 srlD Escherichia coli UTI89 sorbitol-6-phosphate dehydrogenase YP_542050.1 2986130 D 364106 CDS YP_542051.1 91212065 3990220 2987015..2987374 1 NC_007946.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2987374 gutM 3990220 gutM Escherichia coli UTI89 DNA-binding transcriptional activator GutM YP_542051.1 2987015 D 364106 CDS YP_542052.1 91212066 3990221 2987441..2988214 1 NC_007946.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2988214 srlR 3990221 srlR Escherichia coli UTI89 DNA-binding transcriptional repressor SrlR YP_542052.1 2987441 D 364106 CDS YP_542053.1 91212067 3990222 2988207..2989172 1 NC_007946.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2989172 gutQ 3990222 gutQ Escherichia coli UTI89 D-arabinose 5-phosphate isomerase YP_542053.1 2988207 D 364106 CDS YP_542054.1 91212068 3990223 complement(2989169..2990683) 1 NC_007946.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator 2990683 ygaA 3990223 ygaA Escherichia coli UTI89 anaerobic nitric oxide reductase transcription regulator YP_542054.1 2989169 R 364106 CDS YP_542055.1 91212069 3990224 2990870..2992309 1 NC_007946.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2992309 norV 3990224 norV Escherichia coli UTI89 anaerobic nitric oxide reductase flavorubredoxin YP_542055.1 2990870 D 364106 CDS YP_542056.1 91212070 3990225 2992306..2993439 1 NC_007946.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2993439 ygbD 3990225 ygbD Escherichia coli UTI89 nitric oxide reductase YP_542056.1 2992306 D 364106 CDS YP_542057.1 91212071 3990226 complement(2993663..2995987) 1 NC_007946.1 hydrogenase maturation protein HypF 2995987 hypF 3990226 hypF Escherichia coli UTI89 hydrogenase maturation protein HypF YP_542057.1 2993663 R 364106 CDS YP_542058.1 91212072 3990227 complement(2996068..2996610) 1 NC_007946.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 2996610 hydN 3990227 hydN Escherichia coli UTI89 electron transport protein HydN YP_542058.1 2996068 R 364106 CDS YP_542059.1 91212073 3990228 complement(2996744..2997796) 1 NC_007946.1 ascBF operon repressor 2997796 ascG 3990228 ascG Escherichia coli UTI89 ascBF operon repressor YP_542059.1 2996744 R 364106 CDS YP_542060.1 91212074 3990229 2998014..2999471 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC 2999471 ascF 3990229 ascF Escherichia coli UTI89 PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC YP_542060.1 2998014 D 364106 CDS YP_542061.1 91212075 3989998 2999480..3000904 1 NC_007946.1 cryptic 6-phospho-beta-glucosidase 3000904 ascB 3989998 ascB Escherichia coli UTI89 cryptic 6-phospho-beta-glucosidase YP_542061.1 2999480 D 364106 CDS YP_542062.1 91212076 3989999 complement(3001002..3001421) 1 NC_007946.1 hypothetical protein 3001421 ygjM 3989999 ygjM Escherichia coli UTI89 hypothetical protein YP_542062.1 3001002 R 364106 CDS YP_542063.1 91212077 3990000 complement(3001666..3002136) 1 NC_007946.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3002136 hycI 3990000 hycI Escherichia coli UTI89 hydrogenase 3 maturation protease YP_542063.1 3001666 R 364106 CDS YP_542064.1 91212078 3990001 complement(3002129..3002539) 1 NC_007946.1 formate hydrogenlyase maturation protein HycH 3002539 hycH 3990001 hycH Escherichia coli UTI89 formate hydrogenlyase maturation protein HycH YP_542064.1 3002129 R 364106 CDS YP_542065.1 91212079 3990002 complement(3002536..3003303) 1 NC_007946.1 formate hydrogenlyase subunit 7 3003303 hycG 3990002 hycG Escherichia coli UTI89 formate hydrogenlyase subunit 7 YP_542065.1 3002536 R 364106 CDS YP_542066.1 91212080 3990003 complement(3003303..3003845) 1 NC_007946.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3003845 hycF 3990003 hycF Escherichia coli UTI89 formate hydrogenlyase complex iron-sulfur subunit YP_542066.1 3003303 R 364106 CDS YP_542067.1 91212081 3990004 complement(3003855..3005564) 1 NC_007946.1 formate hydrogenlyase subunit 5 3005564 hycE 3990004 hycE Escherichia coli UTI89 formate hydrogenlyase subunit 5 YP_542067.1 3003855 R 364106 CDS YP_542068.1 91212082 3990005 complement(3005582..3006505) 1 NC_007946.1 membrane-spanning protein of formate hydrogenase 3006505 hycD 3990005 hycD Escherichia coli UTI89 membrane-spanning protein of formate hydrogenase YP_542068.1 3005582 R 364106 CDS YP_542069.1 91212083 3990006 complement(3006508..3008334) 1 NC_007946.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3008334 hycC 3990006 hycC Escherichia coli UTI89 formate hydrogenlyase subunit 3 YP_542069.1 3006508 R 364106 CDS YP_542070.1 91212084 3990007 complement(3008331..3008942) 1 NC_007946.1 formate hydrogenlyase subunit 2 3008942 hycB 3990007 hycB Escherichia coli UTI89 formate hydrogenlyase subunit 2 YP_542070.1 3008331 R 364106 CDS YP_542071.1 91212085 3990008 complement(3009067..3009528) 1 NC_007946.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3009528 hycA 3990008 hycA Escherichia coli UTI89 formate hydrogenlyase regulatory protein HycA YP_542071.1 3009067 R 364106 CDS YP_542072.1 91212086 3990009 3009728..3010090 1 NC_007946.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3010090 hypA 3990009 hypA Escherichia coli UTI89 hydrogenase nickel incorporation protein YP_542072.1 3009728 D 364106 CDS YP_542073.1 91212087 3990010 3010094..3010966 1 NC_007946.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3010966 hypB 3990010 hypB Escherichia coli UTI89 hydrogenase nickel incorporation protein HypB YP_542073.1 3010094 D 364106 CDS YP_542074.1 91212088 3990011 3010957..3011229 1 NC_007946.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3011229 hypC 3990011 hypC Escherichia coli UTI89 hydrogenase assembly chaperone YP_542074.1 3010957 D 364106 CDS YP_542075.1 91212089 3990012 3011229..3012350 1 NC_007946.1 hydrogenase isoenzymes formation protein HypD 3012350 hypD 3990012 hypD Escherichia coli UTI89 hydrogenase isoenzymes formation protein HypD YP_542075.1 3011229 D 364106 CDS YP_542076.1 91212090 3990013 3012347..3013357 1 NC_007946.1 hydrogenase isoenzymes formation protein HypE 3013357 hypE 3990013 hypE Escherichia coli UTI89 hydrogenase isoenzymes formation protein HypE YP_542076.1 3012347 D 364106 CDS YP_542077.1 91212091 3990014 3013395..3015509 1 NC_007946.1 formate hydrogenlyase transcriptional activator 3015509 fhlA 3990014 fhlA Escherichia coli UTI89 formate hydrogenlyase transcriptional activator YP_542077.1 3013395 D 364106 CDS YP_542078.1 91212092 3990015 3015515..3015982 1 NC_007946.1 potential molybdenum-pterin-binding-protein 3015982 3990015 UTI89_C3095 Escherichia coli UTI89 potential molybdenum-pterin-binding-protein YP_542078.1 3015515 D 364106 CDS YP_542079.1 91212093 3990016 complement(3016021..3016365) 1 NC_007946.1 hypothetical protein 3016365 ygbA 3990016 ygbA Escherichia coli UTI89 hypothetical protein YP_542079.1 3016021 R 364106 CDS YP_542080.1 91212094 3994194 complement(3016420..3016575) 1 NC_007946.1 hypothetical protein 3016575 3994194 UTI89_C3097 Escherichia coli UTI89 hypothetical protein YP_542080.1 3016420 R 364106 CDS YP_542081.1 91212095 3994195 3016651..3019212 1 NC_007946.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3019212 mutS 3994195 mutS Escherichia coli UTI89 DNA mismatch repair protein MutS YP_542081.1 3016651 D 364106 CDS YP_542082.1 91212096 3994196 complement(3019477..3019980) 1 NC_007946.1 InsBcp5 protein 3019980 insBcp5 3994196 insBcp5 Escherichia coli UTI89 InsBcp5 protein YP_542082.1 3019477 R 364106 CDS YP_542083.1 91212097 3994197 complement(3019991..3020203) 1 NC_007946.1 hypothetical protein 3020203 3994197 UTI89_C3100 Escherichia coli UTI89 hypothetical protein YP_542083.1 3019991 R 364106 CDS YP_542084.1 91212098 3994198 complement(3020604..3021401) 1 NC_007946.1 transcriptional regulator YgbI 3021401 ygbI 3994198 ygbI Escherichia coli UTI89 transcriptional regulator YgbI YP_542084.1 3020604 R 364106 CDS YP_542085.1 91212099 3994199 3021567..3022475 1 NC_007946.1 oxidoreductase YgbJ 3022475 ygbJ 3994199 ygbJ Escherichia coli UTI89 oxidoreductase YgbJ YP_542085.1 3021567 D 364106 CDS YP_542086.1 91212100 3994200 3022472..3023734 1 NC_007946.1 hypothetical protein 3023734 ygbK 3994200 ygbK Escherichia coli UTI89 hypothetical protein YP_542086.1 3022472 D 364106 CDS YP_542087.1 91212101 3994201 3023731..3024369 1 NC_007946.1 aldolase 3024369 ygbL 3994201 ygbL Escherichia coli UTI89 aldolase YP_542087.1 3023731 D 364106 CDS YP_542088.1 91212102 3994202 3024374..3025150 1 NC_007946.1 hypothetical protein 3025150 ygbM 3994202 ygbM Escherichia coli UTI89 hypothetical protein YP_542088.1 3024374 D 364106 CDS YP_542089.1 91212103 3994203 3025239..3026603 1 NC_007946.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3026603 ygbN 3994203 ygbN Escherichia coli UTI89 inner membrane permease YgbN YP_542089.1 3025239 D 364106 CDS YP_542090.1 91212104 3994204 complement(3026746..3027789) 1 NC_007946.1 hypothetical protein 3027789 3994204 UTI89_C3107 Escherichia coli UTI89 hypothetical protein YP_542090.1 3026746 R 364106 CDS YP_542091.1 91212105 3994205 3027808..3027954 1 NC_007946.1 hypothetical protein 3027954 3994205 UTI89_C3108 Escherichia coli UTI89 hypothetical protein YP_542091.1 3027808 D 364106 CDS YP_542092.1 91212106 3994206 3028014..3028565 1 NC_007946.1 hypothetical protein 3028565 3994206 UTI89_C3109 Escherichia coli UTI89 hypothetical protein YP_542092.1 3028014 D 364106 CDS YP_542093.1 91212107 3994207 3028683..3029309 1 NC_007946.1 hypothetical protein 3029309 3994207 UTI89_C3110 Escherichia coli UTI89 hypothetical protein YP_542093.1 3028683 D 364106 CDS YP_542094.1 91212108 3994208 complement(3028743..3029771) 1 NC_007946.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3029771 rpoS 3994208 rpoS Escherichia coli UTI89 RNA polymerase sigma factor RpoS YP_542094.1 3028743 R 364106 CDS YP_542095.1 91212109 3994209 complement(3029798..3030937) 1 NC_007946.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3030937 nlpD 3994209 nlpD Escherichia coli UTI89 lipoprotein NlpD YP_542095.1 3029798 R 364106 CDS YP_542096.1 91212110 3994210 3030795..3030962 1 NC_007946.1 hypothetical protein 3030962 3994210 UTI89_C3113 Escherichia coli UTI89 hypothetical protein YP_542096.1 3030795 D 364106 CDS YP_542097.1 91212111 3994211 complement(3031077..3031703) 1 NC_007946.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3031703 pcm 3994211 pcm Escherichia coli UTI89 protein-L-isoaspartate O-methyltransferase YP_542097.1 3031077 R 364106 CDS YP_542098.1 91212112 3994212 complement(3031697..3032503) 1 NC_007946.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3032503 surE 3994212 surE Escherichia coli UTI89 stationary phase survival protein SurE YP_542098.1 3031697 R 364106 CDS YP_542099.1 91212113 3994213 complement(3032439..3033488) 1 NC_007946.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3033488 truD 3994213 truD Escherichia coli UTI89 tRNA pseudouridine synthase D YP_542099.1 3032439 R 364106 CDS YP_542100.1 91212114 3990442 complement(3033485..3033964) 1 NC_007946.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3033964 ispF 3990442 ispF Escherichia coli UTI89 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_542100.1 3033485 R 364106 CDS YP_542101.1 91212115 3990443 complement(3033964..3034674) 1 NC_007946.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3034674 ispD 3990443 ispD Escherichia coli UTI89 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_542101.1 3033964 R 364106 CDS YP_542102.1 91212116 3990444 complement(3034693..3035004) 1 NC_007946.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3035004 ftsB 3990444 ftsB Escherichia coli UTI89 cell division protein FtsB YP_542102.1 3034693 R 364106 CDS YP_542103.1 91212117 3990445 complement(3035197..3035520) 1 NC_007946.1 hypothetical protein 3035520 ygbE 3990445 ygbE Escherichia coli UTI89 hypothetical protein YP_542103.1 3035197 R 364106 CDS YP_542104.1 91212118 3990446 complement(3035570..3036175) 1 NC_007946.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3036175 cysC 3990446 cysC Escherichia coli UTI89 adenylylsulfate kinase YP_542104.1 3035570 R 364106 CDS YP_542105.1 91212119 3990447 complement(3036175..3037602) 1 NC_007946.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3037602 cysN 3990447 cysN Escherichia coli UTI89 sulfate adenylyltransferase subunit 1 YP_542105.1 3036175 R 364106 CDS YP_542106.1 91212120 3990448 complement(3037604..3038512) 1 NC_007946.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3038512 cysD 3990448 cysD Escherichia coli UTI89 sulfate adenylyltransferase subunit 2 YP_542106.1 3037604 R 364106 CDS YP_542107.1 91212121 3990449 3038764..3039801 1 NC_007946.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3039801 iap 3990449 iap Escherichia coli UTI89 alkaline phosphatase YP_542107.1 3038764 D 364106 CDS YP_542108.1 91212122 3990450 complement(3039926..3040078) 1 NC_007946.1 hypothetical protein 3040078 3990450 UTI89_C3125 Escherichia coli UTI89 hypothetical protein YP_542108.1 3039926 R 364106 CDS YP_542109.1 91212123 3990451 complement(3040343..3041077) 1 NC_007946.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3041077 cysH 3990451 cysH Escherichia coli UTI89 phosphoadenosine phosphosulfate reductase YP_542109.1 3040343 R 364106 CDS YP_542110.1 91212124 3990452 complement(3041151..3042863) 1 NC_007946.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3042863 cysI 3990452 cysI Escherichia coli UTI89 sulfite reductase subunit beta YP_542110.1 3041151 R 364106 CDS YP_542111.1 91212125 3990453 complement(3042863..3044662) 1 NC_007946.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3044662 cysJ 3990453 cysJ Escherichia coli UTI89 sulfite reductase subunit alpha YP_542111.1 3042863 R 364106 CDS YP_542112.1 91212126 3990454 3044894..3045343 1 NC_007946.1 6-pyruvoyl tetrahydrobiopterin synthase 3045343 ygcM 3990454 ygcM Escherichia coli UTI89 6-pyruvoyl tetrahydrobiopterin synthase YP_542112.1 3044894 D 364106 CDS YP_542113.1 91212127 3990455 3045391..3046692 1 NC_007946.1 electron transfer flavoprotein-quinone oxidoreductase ygcN 3046692 ygcN 3990455 ygcN Escherichia coli UTI89 electron transfer flavoprotein-quinone oxidoreductase ygcN YP_542113.1 3045391 D 364106 CDS YP_542114.1 91212128 3990456 3046647..3046943 1 NC_007946.1 ferredoxin-like protein YgcO 3046943 ygcO 3990456 ygcO Escherichia coli UTI89 ferredoxin-like protein YgcO YP_542114.1 3046647 D 364106 CDS YP_542115.1 91212129 3990457 3046960..3047535 1 NC_007946.1 anti-terminator regulatory protein 3047535 ygcP 3990457 ygcP Escherichia coli UTI89 anti-terminator regulatory protein YP_542115.1 3046960 D 364106 CDS YP_542116.1 91212130 3990458 complement(3047683..3048576) 1 NC_007946.1 flavoprotein 3048576 ygcQ 3990458 ygcQ Escherichia coli UTI89 flavoprotein YP_542116.1 3047683 R 364106 CDS YP_542117.1 91212131 3990459 complement(3048540..3049325) 1 NC_007946.1 transport protein 3049325 ygcR 3990459 ygcR Escherichia coli UTI89 transport protein YP_542117.1 3048540 R 364106 CDS YP_542118.1 91212132 3990460 complement(3049297..3050706) 1 NC_007946.1 metabolite transport protein YgcS 3050706 ygcS 3990460 ygcS Escherichia coli UTI89 metabolite transport protein YgcS YP_542118.1 3049297 R 364106 CDS YP_542119.1 91212133 3993679 complement(3050728..3052182) 1 NC_007946.1 hypothetical protein 3052182 3993679 UTI89_C3136 Escherichia coli UTI89 hypothetical protein YP_542119.1 3050728 R 364106 CDS YP_542120.1 91212134 3993680 complement(3052252..3053112) 1 NC_007946.1 oxidoreductase YgcW 3053112 ygcW 3993680 ygcW Escherichia coli UTI89 oxidoreductase YgcW YP_542120.1 3052252 R 364106 CDS YP_542121.1 91212135 3993681 3053356..3054633 1 NC_007946.1 hypothetical protein 3054633 yqcE 3993681 yqcE Escherichia coli UTI89 hypothetical protein YP_542121.1 3053356 D 364106 CDS YP_542122.1 91212136 3993682 3054660..3056138 1 NC_007946.1 sugar kinase YgcE 3056138 ygcE 3993682 ygcE Escherichia coli UTI89 sugar kinase YgcE YP_542122.1 3054660 D 364106 CDS YP_542123.1 91212137 3993683 complement(3056612..3057283) 1 NC_007946.1 hypothetical protein 3057283 ygcF 3993683 ygcF Escherichia coli UTI89 hypothetical protein YP_542123.1 3056612 R 364106 CDS YP_542124.1 91212138 3993684 3057317..3057442 1 NC_007946.1 hypothetical protein 3057442 3993684 UTI89_C3141 Escherichia coli UTI89 hypothetical protein YP_542124.1 3057317 D 364106 CDS YP_542125.1 91212139 3993685 3057456..3058070 1 NC_007946.1 hypothetical protein 3058070 3993685 UTI89_C3142 Escherichia coli UTI89 hypothetical protein YP_542125.1 3057456 D 364106 CDS YP_542126.1 91212140 3993686 3058054..3058977 1 NC_007946.1 hypothetical protein 3058977 3993686 UTI89_C3143 Escherichia coli UTI89 hypothetical protein YP_542126.1 3058054 D 364106 CDS YP_542127.1 91212141 3993687 complement(3058581..3058871) 1 NC_007946.1 hypothetical protein 3058871 3993687 UTI89_C3144 Escherichia coli UTI89 hypothetical protein YP_542127.1 3058581 R 364106 CDS YP_542128.1 91212142 3993688 3058992..3060140 1 NC_007946.1 hypothetical protein 3060140 3993688 UTI89_C3145 Escherichia coli UTI89 hypothetical protein YP_542128.1 3058992 D 364106 CDS YP_542130.1 91212144 3993690 3060134..3061039 1 NC_007946.1 hypothetical protein 3061039 3993690 UTI89_C3147 Escherichia coli UTI89 hypothetical protein YP_542130.1 3060134 D 364106 CDS YP_542131.1 91212145 3993691 complement(3061099..3062397) 1 NC_007946.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3062397 eno 3993691 eno Escherichia coli UTI89 phosphopyruvate hydratase YP_542131.1 3061099 R 364106 CDS YP_542132.1 91212146 3993692 complement(3062485..3064122) 1 NC_007946.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3064122 pyrG 3993692 pyrG Escherichia coli UTI89 CTP synthetase YP_542132.1 3062485 R 364106 CDS YP_542133.1 91212147 3993693 complement(3064350..3065141) 1 NC_007946.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 3065141 mazG 3993693 mazG Escherichia coli UTI89 nucleoside triphosphate pyrophosphohydrolase YP_542133.1 3064350 R 364106 CDS YP_542134.1 91212148 3993694 complement(3065213..3065548) 1 NC_007946.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 3065548 chpA 3993694 chpA Escherichia coli UTI89 toxin ChpA YP_542134.1 3065213 R 364106 CDS YP_542135.1 91212149 3993695 3065465..3065827 1 NC_007946.1 hypothetical protein 3065827 3993695 UTI89_C3152 Escherichia coli UTI89 hypothetical protein YP_542135.1 3065465 D 364106 CDS YP_542136.1 91212150 3993696 complement(3065548..3065796) 1 NC_007946.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 3065796 chpR 3993696 chpR Escherichia coli UTI89 antitoxin MazE YP_542136.1 3065548 R 364106 CDS YP_542137.1 91212151 3993697 complement(3065874..3068108) 1 NC_007946.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3068108 relA 3993697 relA Escherichia coli UTI89 GDP/GTP pyrophosphokinase YP_542137.1 3065874 R 364106 CDS YP_542138.1 91212152 3993698 complement(3068156..3069457) 1 NC_007946.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3069457 rumA 3993698 rumA Escherichia coli UTI89 23S rRNA 5-methyluridine methyltransferase YP_542138.1 3068156 R 364106 CDS YP_542139.1 91212153 3990291 3069514..3072270 1 NC_007946.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3072270 barA 3990291 barA Escherichia coli UTI89 hybrid sensory histidine kinase BarA YP_542139.1 3069514 D 364106 CDS YP_542140.1 91212154 3990292 complement(3072501..3073841) 1 NC_007946.1 synonym: gdh1, b2787, ygcX, EG13167; glucarate dehydratase 3073841 gudD 3990292 gudD Escherichia coli UTI89 glucarate dehydratase YP_542140.1 3072501 R 364106 CDS YP_542141.1 91212155 3990293 complement(3073862..3075202) 1 NC_007946.1 glucarate dehydratase related protein 3075202 ygcY 3990293 ygcY Escherichia coli UTI89 glucarate dehydratase related protein YP_542141.1 3073862 R 364106 CDS YP_542142.1 91212156 3990294 complement(3075204..3076556) 1 NC_007946.1 glucarate transporter 3076556 3990294 UTI89_C3159 Escherichia coli UTI89 glucarate transporter YP_542142.1 3075204 R 364106 CDS YP_542143.1 91212157 3990295 complement(3076990..3077439) 1 NC_007946.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3077439 yqcA 3990295 yqcA Escherichia coli UTI89 flavodoxin YP_542143.1 3076990 R 364106 CDS YP_542144.1 91212158 3990296 complement(3077457..3078239) 1 NC_007946.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3078239 truC 3990296 truC Escherichia coli UTI89 tRNA pseudouridine synthase C YP_542144.1 3077457 R 364106 CDS YP_542145.1 91212159 3990297 complement(3078239..3078568) 1 NC_007946.1 hypothetical protein 3078568 yqcC 3990297 yqcC Escherichia coli UTI89 hypothetical protein YP_542145.1 3078239 R 364106 CDS YP_542146.1 91212160 3990298 complement(3079190..3079735) 1 NC_007946.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3079735 syd 3990298 syd Escherichia coli UTI89 SecY interacting protein Syd YP_542146.1 3079190 R 364106 CDS YP_542147.1 91212161 3990299 3079803..3080651 1 NC_007946.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3080651 queF 3990299 queF Escherichia coli UTI89 7-cyano-7-deazaguanine reductase YP_542147.1 3079803 D 364106 CDS YP_542148.1 91212162 3990300 3080763..3082127 1 NC_007946.1 hypothetical protein 3082127 ygdH 3990300 ygdH Escherichia coli UTI89 hypothetical protein YP_542148.1 3080763 D 364106 CDS YP_542149.1 91212163 3990301 complement(3082657..3084084) 1 NC_007946.1 hypothetical protein 3084084 3990301 UTI89_C3166 Escherichia coli UTI89 hypothetical protein YP_542149.1 3082657 R 364106 CDS YP_542150.1 91212164 3990302 3082684..3083973 1 NC_007946.1 serine transporter 3083973 sdaC 3990302 sdaC Escherichia coli UTI89 serine transporter YP_542150.1 3082684 D 364106 CDS YP_542151.1 91212165 3990303 3084031..3085398 1 NC_007946.1 L-serine dehydratase (deaminase), L-SD2 3085398 sdaB 3990303 sdaB Escherichia coli UTI89 L-serine dehydratase (deaminase), L-SD2 YP_542151.1 3084031 D 364106 CDS YP_542152.1 91212166 3990304 3085420..3086265 1 NC_007946.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3086265 xni 3990304 xni Escherichia coli UTI89 exonuclease IX YP_542152.1 3085420 D 364106 CDS YP_542153.1 91212167 3990305 complement(3086370..3087521) 1 NC_007946.1 L-1,2-propanediol oxidoreductase 3087521 fucO 3990305 fucO Escherichia coli UTI89 L-1,2-propanediol oxidoreductase YP_542153.1 3086370 R 364106 CDS YP_542154.1 91212168 3990306 complement(3087546..3088193) 1 NC_007946.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3088193 fucA 3990306 fucA Escherichia coli UTI89 L-fuculose phosphate aldolase YP_542154.1 3087546 R 364106 CDS YP_542155.1 91212169 3990307 3088383..3088520 1 NC_007946.1 hypothetical protein 3088520 3990307 UTI89_C3172 Escherichia coli UTI89 hypothetical protein YP_542155.1 3088383 D 364106 CDS YP_542156.1 91212170 3990308 3088740..3090056 1 NC_007946.1 L-fucose transporter 3090056 fucP 3990308 fucP Escherichia coli UTI89 L-fucose transporter YP_542156.1 3088740 D 364106 CDS YP_542157.1 91212171 3990309 3090089..3091864 1 NC_007946.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3091864 fucI 3990309 fucI Escherichia coli UTI89 L-fucose isomerase YP_542157.1 3090089 D 364106 CDS YP_542158.1 91212172 3990275 3091943..3093391 1 NC_007946.1 L-fuculokinase 3093391 fucK 3990275 fucK Escherichia coli UTI89 L-fuculokinase YP_542158.1 3091943 D 364106 CDS YP_542159.1 91212173 3990276 3093393..3093815 1 NC_007946.1 protein of fucose operon 3093815 fucU 3990276 fucU Escherichia coli UTI89 protein of fucose operon YP_542159.1 3093393 D 364106 CDS YP_542160.1 91212174 3990277 3093864..3094604 1 NC_007946.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3094604 fucR 3990277 fucR Escherichia coli UTI89 DNA-binding transcriptional activator FucR YP_542160.1 3093864 D 364106 CDS YP_542161.1 91212175 3990278 complement(3094648..3095748) 1 NC_007946.1 RNA 2'-O-ribose methyltransferase 3095748 ygdE 3990278 ygdE Escherichia coli UTI89 RNA 2'-O-ribose methyltransferase YP_542161.1 3094648 R 364106 CDS YP_542162.1 91212176 3990279 complement(3095741..3096043) 1 NC_007946.1 hypothetical protein 3096043 ygdD 3990279 ygdD Escherichia coli UTI89 hypothetical protein YP_542162.1 3095741 R 364106 CDS YP_542163.1 91212177 3990280 complement(3096155..3097072) 1 NC_007946.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3097072 gcvA 3990280 gcvA Escherichia coli UTI89 DNA-binding transcriptional activator GcvA YP_542163.1 3096155 R 364106 CDS YP_542164.1 91212178 3990281 3097390..3097683 1 NC_007946.1 hypothetical protein 3097683 3990281 UTI89_C3181 Escherichia coli UTI89 hypothetical protein YP_542164.1 3097390 D 364106 CDS YP_542165.1 91212179 3990282 complement(3097423..3097653) 1 NC_007946.1 hypothetical protein 3097653 3990282 UTI89_C3182 Escherichia coli UTI89 hypothetical protein YP_542165.1 3097423 R 364106 CDS YP_542166.1 91212180 3990283 3097806..3099047 1 NC_007946.1 cysteine sulfinate desulfinase 3099047 3990283 UTI89_C3183 Escherichia coli UTI89 cysteine sulfinate desulfinase YP_542166.1 3097806 D 364106 CDS YP_542167.1 91212181 3990284 3099047..3099490 1 NC_007946.1 hypothetical protein 3099490 ygdK 3990284 ygdK Escherichia coli UTI89 hypothetical protein YP_542167.1 3099047 D 364106 CDS YP_542168.1 91212182 3990285 complement(3099541..3100347) 1 NC_007946.1 hypothetical protein 3100347 ygdL 3990285 ygdL Escherichia coli UTI89 hypothetical protein YP_542168.1 3099541 R 364106 CDS YP_542169.2 162138382 3990286 complement(3100424..3101521) 1 NC_007946.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3101521 mltA 3990286 mltA Escherichia coli UTI89 murein transglycosylase A YP_542169.2 3100424 R 364106 CDS YP_542170.1 91212184 3990290 3102641..3103162 1 NC_007946.1 hypothetical protein 3103162 3990290 UTI89_C3190 Escherichia coli UTI89 hypothetical protein YP_542170.1 3102641 D 364106 CDS YP_542171.1 91212185 3993868 3103215..3104759 1 NC_007946.1 hypothetical protein 3104759 3993868 UTI89_C3191 Escherichia coli UTI89 hypothetical protein YP_542171.1 3103215 D 364106 CDS YP_542172.1 91212186 3993869 3104777..3106114 1 NC_007946.1 hypothetical protein 3106114 3993869 UTI89_C3192 Escherichia coli UTI89 hypothetical protein YP_542172.1 3104777 D 364106 CDS YP_542173.1 91212187 3993870 3106111..3106776 1 NC_007946.1 hypothetical protein 3106776 3993870 UTI89_C3193 Escherichia coli UTI89 hypothetical protein YP_542173.1 3106111 D 364106 CDS YP_542174.1 91212188 3993871 3106789..3108441 1 NC_007946.1 hypothetical protein 3108441 3993871 UTI89_C3194 Escherichia coli UTI89 hypothetical protein YP_542174.1 3106789 D 364106 CDS YP_542175.1 91212189 3993872 complement(3108478..3109080) 1 NC_007946.1 hypothetical protein 3109080 3993872 UTI89_C3195 Escherichia coli UTI89 hypothetical protein YP_542175.1 3108478 R 364106 CDS YP_542176.1 91212190 3993873 3108499..3108990 1 NC_007946.1 secreted protein Hcp 3108990 3993873 UTI89_C3196 Escherichia coli UTI89 secreted protein Hcp YP_542176.1 3108499 D 364106 CDS YP_542177.1 91212191 3993874 3109182..3111827 1 NC_007946.1 ClpB protein 3111827 3993874 UTI89_C3197 Escherichia coli UTI89 ClpB protein YP_542177.1 3109182 D 364106 CDS YP_542178.1 91212192 3993875 3111839..3114319 1 NC_007946.1 hypothetical protein 3114319 3993875 UTI89_C3198 Escherichia coli UTI89 hypothetical protein YP_542178.1 3111839 D 364106 CDS YP_542179.1 91212193 3993876 3114339..3116108 1 NC_007946.1 hypothetical protein 3116108 3993876 UTI89_C3199 Escherichia coli UTI89 hypothetical protein YP_542179.1 3114339 D 364106 CDS YP_542180.1 91212194 3993877 3116083..3116916 1 NC_007946.1 hypothetical protein 3116916 3993877 UTI89_C3200 Escherichia coli UTI89 hypothetical protein YP_542180.1 3116083 D 364106 CDS YP_542181.1 91212195 3993878 3116885..3117178 1 NC_007946.1 hypothetical protein 3117178 3993878 UTI89_C3201 Escherichia coli UTI89 hypothetical protein YP_542181.1 3116885 D 364106 CDS YP_542182.1 91212196 3993879 3117642..3117902 1 NC_007946.1 hypothetical protein 3117902 3993879 UTI89_C3202 Escherichia coli UTI89 hypothetical protein YP_542182.1 3117642 D 364106 CDS YP_542183.1 91212197 3993880 3117829..3119040 1 NC_007946.1 hypothetical protein 3119040 3993880 UTI89_C3203 Escherichia coli UTI89 hypothetical protein YP_542183.1 3117829 D 364106 CDS YP_542184.1 91212198 3993881 3119050..3122403 1 NC_007946.1 hypothetical protein 3122403 3993881 UTI89_C3204 Escherichia coli UTI89 hypothetical protein YP_542184.1 3119050 D 364106 CDS YP_542185.1 91212199 3993882 3122369..3124006 1 NC_007946.1 hypothetical protein 3124006 3993882 UTI89_C3205 Escherichia coli UTI89 hypothetical protein YP_542185.1 3122369 D 364106 CDS YP_542186.1 91212200 3993883 3125577..3126218 1 NC_007946.1 hypothetical protein 3126218 3993883 UTI89_C3206 Escherichia coli UTI89 hypothetical protein YP_542186.1 3125577 D 364106 CDS YP_542187.1 91212201 3993884 3126499..3126918 1 NC_007946.1 hypothetical protein 3126918 3993884 UTI89_C3207 Escherichia coli UTI89 hypothetical protein YP_542187.1 3126499 D 364106 CDS YP_542188.1 91212202 3993885 3130072..3130608 1 NC_007946.1 hypothetical protein 3130608 3993885 UTI89_C3208 Escherichia coli UTI89 hypothetical protein YP_542188.1 3130072 D 364106 CDS YP_542189.1 91212203 3993886 3130612..3131040 1 NC_007946.1 hypothetical protein 3131040 3993886 UTI89_C3209 Escherichia coli UTI89 hypothetical protein YP_542189.1 3130612 D 364106 CDS YP_542190.1 91212204 3993887 3131040..3132416 1 NC_007946.1 hypothetical protein 3132416 3993887 UTI89_C3210 Escherichia coli UTI89 hypothetical protein YP_542190.1 3131040 D 364106 CDS YP_542191.1 91212205 3991203 complement(3131590..3131742) 1 NC_007946.1 hypothetical protein 3131742 3991203 UTI89_C3211 Escherichia coli UTI89 hypothetical protein YP_542191.1 3131590 R 364106 CDS YP_542192.1 91212206 3991204 complement(3132718..3133674) 1 NC_007946.1 2-hydroxyacid dehydrogenase 3133674 3991204 UTI89_C3212 Escherichia coli UTI89 2-hydroxyacid dehydrogenase YP_542192.1 3132718 R 364106 CDS YP_542193.1 91212207 3991205 complement(3133737..3134333) 1 NC_007946.1 phosphosugar isomerase 3134333 3991205 UTI89_C3213 Escherichia coli UTI89 phosphosugar isomerase YP_542193.1 3133737 R 364106 CDS YP_542194.1 91212208 3991206 complement(3134336..3135511) 1 NC_007946.1 beta-cystathionase 3135511 3991206 UTI89_C3214 Escherichia coli UTI89 beta-cystathionase YP_542194.1 3134336 R 364106 CDS YP_542195.1 91212209 3991207 complement(3135511..3137091) 1 NC_007946.1 PTS system maltose and glucose-specific transporter subunit IIABC 3137091 3991207 UTI89_C3215 Escherichia coli UTI89 PTS system maltose and glucose-specific transporter subunit IIABC YP_542195.1 3135511 R 364106 CDS YP_542196.1 91212210 3991208 complement(3137123..3137992) 1 NC_007946.1 antiterminator 3137992 3991208 UTI89_C3216 Escherichia coli UTI89 antiterminator YP_542196.1 3137123 R 364106 CDS YP_542197.1 91212211 3991209 3138031..3138183 1 NC_007946.1 hypothetical protein 3138183 3991209 UTI89_C3217 Escherichia coli UTI89 hypothetical protein YP_542197.1 3138031 D 364106 CDS YP_542198.1 91212212 3991210 complement(3138193..3139536) 1 NC_007946.1 N-acetylmuramoyl-L-alanine amidase 3139536 amiC 3991210 amiC Escherichia coli UTI89 N-acetylmuramoyl-L-alanine amidase YP_542198.1 3138193 R 364106 CDS YP_542199.2 162138381 3991211 3139678..3141009 1 NC_007946.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3141009 argA 3991211 argA Escherichia coli UTI89 N-acetylglutamate synthase YP_542199.2 3139678 D 364106 CDS YP_542200.1 91212214 3991212 complement(3141071..3142897) 1 NC_007946.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3142897 recD 3991212 recD Escherichia coli UTI89 exonuclease V subunit alpha YP_542200.1 3141071 R 364106 CDS YP_542201.1 91212215 3991213 complement(3142897..3146448) 1 NC_007946.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3146448 recB 3991213 recB Escherichia coli UTI89 exonuclease V subunit beta YP_542201.1 3142897 R 364106 CDS YP_542202.1 91212216 3991214 complement(3146432..3149320) 1 NC_007946.1 synonym: b2821, ptr; protease III 3149320 ptrA 3991214 ptrA Escherichia coli UTI89 protease III YP_542202.1 3146432 R 364106 CDS YP_542203.1 91212217 3991215 complement(3149496..3152864) 1 NC_007946.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3152864 recC 3991215 recC Escherichia coli UTI89 exonuclease V subunit gamma YP_542203.1 3149496 R 364106 CDS YP_542204.1 91212218 3991216 complement(3152877..3153200) 1 NC_007946.1 hypothetical protein 3153200 ppdC 3991216 ppdC Escherichia coli UTI89 hypothetical protein YP_542204.1 3152877 R 364106 CDS YP_542205.1 91212219 3991217 complement(3153185..3153592) 1 NC_007946.1 hypothetical protein 3153592 ygdB 3991217 ygdB Escherichia coli UTI89 hypothetical protein YP_542205.1 3153185 R 364106 CDS YP_542206.1 91212220 3991218 complement(3153589..3154176) 1 NC_007946.1 hypothetical protein 3154176 ppdB 3991218 ppdB Escherichia coli UTI89 hypothetical protein YP_542206.1 3153589 R 364106 CDS YP_542207.1 91212221 3991219 complement(3154143..3154613) 1 NC_007946.1 hypothetical protein 3154613 ppdA 3991219 ppdA Escherichia coli UTI89 hypothetical protein YP_542207.1 3154143 R 364106 CDS YP_542209.1 91212223 3991221 complement(3154798..3155592) 1 NC_007946.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3155592 thyA 3991221 thyA Escherichia coli UTI89 thymidylate synthase YP_542209.1 3154798 R 364106 CDS YP_542210.1 91212224 3994136 complement(3155599..3156474) 1 NC_007946.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3156474 lgt 3994136 lgt Escherichia coli UTI89 prolipoprotein diacylglyceryl transferase YP_542210.1 3155599 R 364106 CDS YP_542211.1 91212225 3994137 complement(3156625..3158871) 1 NC_007946.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3158871 ptsP 3994137 ptsP Escherichia coli UTI89 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_542211.1 3156625 R 364106 CDS YP_542212.1 91212226 3994138 complement(3158884..3159414) 1 NC_007946.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3159414 nudH 3994138 nudH Escherichia coli UTI89 dinucleoside polyphosphate hydrolase YP_542212.1 3158884 R 364106 CDS YP_542213.1 91212227 3994139 complement(3159767..3159913) 1 NC_007946.1 hypothetical protein 3159913 3994139 UTI89_C3233 Escherichia coli UTI89 hypothetical protein YP_542213.1 3159767 R 364106 CDS YP_542214.1 91212228 3994140 3160099..3160788 1 NC_007946.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3160788 mutH 3994140 mutH Escherichia coli UTI89 DNA mismatch repair protein YP_542214.1 3160099 D 364106 CDS YP_542215.1 91212229 3994141 3160857..3161570 1 NC_007946.1 transport protein 3161570 ygdQ 3994141 ygdQ Escherichia coli UTI89 transport protein YP_542215.1 3160857 D 364106 CDS YP_542216.1 91212230 3994142 complement(3161642..3161929) 1 NC_007946.1 hypothetical protein 3161929 3994142 UTI89_C3236 Escherichia coli UTI89 hypothetical protein YP_542216.1 3161642 R 364106 CDS YP_542217.1 91212231 3994143 3161708..3161926 1 NC_007946.1 lipoprotein 3161926 ygdR 3994143 ygdR Escherichia coli UTI89 lipoprotein YP_542217.1 3161708 D 364106 CDS YP_542218.1 91212232 3994144 3162034..3163074 1 NC_007946.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo/keto reductase 3163074 tas 3994144 tas Escherichia coli UTI89 aldo/keto reductase YP_542218.1 3162034 D 364106 CDS YP_542219.1 91212233 3994145 complement(3163106..3164299) 1 NC_007946.1 lysophospholipid transporter LplT 3164299 ygeD 3994145 ygeD Escherichia coli UTI89 lysophospholipid transporter LplT YP_542219.1 3163106 R 364106 CDS YP_542220.1 91212234 3994146 complement(3164292..3166451) 1 NC_007946.1 AAS bifunctional protein; Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3166451 aas 3994146 aas Escherichia coli UTI89 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_542220.1 3164292 R 364106 CDS YP_542221.1 91212235 3994147 3167037..3168068 1 NC_007946.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3168068 galR 3994147 galR Escherichia coli UTI89 DNA-binding transcriptional regulator GalR YP_542221.1 3167037 D 364106 CDS YP_542222.1 91212236 3994148 complement(3168075..3169337) 1 NC_007946.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3169337 lysA 3994148 lysA Escherichia coli UTI89 diaminopimelate decarboxylase YP_542222.1 3168075 R 364106 CDS YP_542223.1 91212237 3994149 3169459..3170394 1 NC_007946.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3170394 lysR 3994149 lysR Escherichia coli UTI89 LysR family transcriptional regulator YP_542223.1 3169459 D 364106 CDS YP_542224.1 91212238 3994150 complement(3170381..3171073) 1 NC_007946.1 racemase 3171073 ygeA 3994150 ygeA Escherichia coli UTI89 racemase YP_542224.1 3170381 R 364106 CDS YP_542225.1 91212239 3994151 complement(3172935..3173696) 1 NC_007946.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3173696 3994151 UTI89_C3245 Escherichia coli UTI89 2-deoxy-D-gluconate 3-dehydrogenase YP_542225.1 3172935 R 364106 CDS YP_542226.1 91212240 3994152 complement(3173726..3174562) 1 NC_007946.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3174562 kduI 3994152 kduI Escherichia coli UTI89 5-keto-4-deoxyuronate isomerase YP_542226.1 3173726 R 364106 CDS YP_542227.1 91212241 3994153 complement(3174849..3176033) 1 NC_007946.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3176033 yqeF 3994153 yqeF Escherichia coli UTI89 acetyl-CoA acetyltransferase YP_542227.1 3174849 R 364106 CDS YP_542228.1 91212242 3994154 3176285..3177514 1 NC_007946.1 transporter protein 3177514 3994154 UTI89_C3248 Escherichia coli UTI89 transporter protein YP_542228.1 3176285 D 364106 CDS YP_542229.1 91212243 3990076 complement(3177983..3178762) 1 NC_007946.1 lipoprotein YgeR 3178762 ygeR 3990076 ygeR Escherichia coli UTI89 lipoprotein YgeR YP_542229.1 3177983 R 364106 CDS YP_542230.1 91212244 3990077 3179152..3181449 1 NC_007946.1 molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3181449 3990077 UTI89_C3251 Escherichia coli UTI89 xanthine dehydrogenase subunit XdhA YP_542230.1 3179152 D 364106 CDS YP_542231.1 91212245 3990078 3181460..3182338 1 NC_007946.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3182338 ygeT 3990078 ygeT Escherichia coli UTI89 xanthine dehydrogenase subunit XdhB YP_542231.1 3181460 D 364106 CDS YP_542232.1 91212246 3990079 3182335..3182814 1 NC_007946.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3182814 3990079 UTI89_C3253 Escherichia coli UTI89 xanthine dehydrogenase subunit XdhC YP_542232.1 3182335 D 364106 CDS YP_542233.1 91212247 3990080 complement(3182854..3184632) 1 NC_007946.1 sigma-54-dependent transcriptional regulator ygeV 3184632 ygeV 3990080 ygeV Escherichia coli UTI89 sigma-54-dependent transcriptional regulator ygeV YP_542233.1 3182854 R 364106 CDS YP_542234.1 91212248 3990081 3185108..3186298 1 NC_007946.1 aspartate/ornithine carbamoyltransferase 3186298 ygeW 3990081 ygeW Escherichia coli UTI89 aspartate/ornithine carbamoyltransferase YP_542234.1 3185108 D 364106 CDS YP_542235.1 91212249 3990082 3186356..3187552 1 NC_007946.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3187552 ygeX 3990082 ygeX Escherichia coli UTI89 diaminopropionate ammonia-lyase YP_542235.1 3186356 D 364106 CDS YP_542236.1 91212250 3990083 3187610..3188821 1 NC_007946.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3188821 ygeY 3990083 ygeY Escherichia coli UTI89 peptidase YP_542236.1 3187610 D 364106 CDS YP_542237.1 91212251 3990084 3188862..3190259 1 NC_007946.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3190259 ygeZ 3990084 ygeZ Escherichia coli UTI89 phenylhydantoinase YP_542237.1 3188862 D 364106 CDS YP_542238.1 91212252 3990085 3190307..3191239 1 NC_007946.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3191239 yqeA 3990085 yqeA Escherichia coli UTI89 carbamate kinase YP_542238.1 3190307 D 364106 CDS YP_542239.1 91212253 3990086 complement(3191280..3192905) 1 NC_007946.1 hypothetical protein 3192905 yqeB 3990086 yqeB Escherichia coli UTI89 hypothetical protein YP_542239.1 3191280 R 364106 CDS YP_542240.1 91212254 3990087 complement(3192953..3193723) 1 NC_007946.1 hypothetical protein 3193723 yqeC 3990087 yqeC Escherichia coli UTI89 hypothetical protein YP_542240.1 3192953 R 364106 CDS YP_542241.1 91212255 3990088 3193827..3194405 1 NC_007946.1 hypothetical protein 3194405 ygfJ 3990088 ygfJ Escherichia coli UTI89 hypothetical protein YP_542241.1 3193827 D 364106 CDS YP_542242.1 91212256 3990089 3194727..3197825 1 NC_007946.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3197825 ygfK 3990089 ygfK Escherichia coli UTI89 selenate reductase subunit YgfK YP_542242.1 3194727 D 364106 CDS YP_542243.1 91212257 3990090 3197828..3199156 1 NC_007946.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3199156 3990090 UTI89_C3264 Escherichia coli UTI89 chlorohydrolase/aminohydrolase YP_542243.1 3197828 D 364106 CDS YP_542244.1 91212258 3990091 3199207..3199986 1 NC_007946.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3199986 ygfM 3990091 ygfM Escherichia coli UTI89 selenate reductase subunit YgfM YP_542244.1 3199207 D 364106 CDS YP_542245.1 91212259 3990092 3199983..3202853 1 NC_007946.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3202853 xdhD 3990092 xdhD Escherichia coli UTI89 selenate reductase subunit YgfN YP_542245.1 3199983 D 364106 CDS YP_542246.1 91212260 3990093 3202961..3204418 1 NC_007946.1 transport protein 3204418 ygfO 3990093 ygfO Escherichia coli UTI89 transport protein YP_542246.1 3202961 D 364106 CDS YP_542247.1 91212261 3992123 3204313..3205752 1 NC_007946.1 Catalyzes the deamination of guanine; guanine deaminase 3205752 ygfP 3992123 ygfP Escherichia coli UTI89 guanine deaminase YP_542247.1 3204313 D 364106 CDS YP_542248.1 91212262 3992124 3205788..3207155 1 NC_007946.1 hypothetical protein 3207155 3992124 UTI89_C3269 Escherichia coli UTI89 hypothetical protein YP_542248.1 3205788 D 364106 CDS YP_542249.1 91212263 3992125 complement(3207191..3207682) 1 NC_007946.1 electron transport protein YgfS 3207682 ygfS 3992125 ygfS Escherichia coli UTI89 electron transport protein YgfS YP_542249.1 3207191 R 364106 CDS YP_542250.1 91212264 3992126 complement(3207679..3209613) 1 NC_007946.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3209613 ygfT 3992126 ygfT Escherichia coli UTI89 oxidoreductase Fe-S binding subunit YP_542250.1 3207679 R 364106 CDS YP_542251.1 91212265 3992127 3209905..3211482 1 NC_007946.1 purine permease YgfU 3211482 ygfU 3992127 ygfU Escherichia coli UTI89 purine permease YgfU YP_542251.1 3209905 D 364106 CDS YP_542252.1 91212266 3992128 3211466..3211609 1 NC_007946.1 hypothetical protein 3211609 3992128 UTI89_C3273 Escherichia coli UTI89 hypothetical protein YP_542252.1 3211466 D 364106 CDS YP_542253.1 91212267 3992129 3211732..3212280 1 NC_007946.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3212280 3992129 UTI89_C3274 Escherichia coli UTI89 isopentenyl-diphosphate delta-isomerase YP_542253.1 3211732 D 364106 CDS YP_542254.1 91212268 3992130 complement(3212323..3213840) 1 NC_007946.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3213840 lysS 3992130 lysS Escherichia coli UTI89 lysyl-tRNA synthetase YP_542254.1 3212323 R 364106 CDS YP_542255.1 91212269 3992131 3212440..3213855 1 NC_007946.1 hypothetical protein 3213855 3992131 UTI89_C3276 Escherichia coli UTI89 hypothetical protein YP_542255.1 3212440 D 364106 CDS YP_542256.1 91212270 3992132 complement(3215039..3216772) 1 NC_007946.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3216772 recJ 3992132 recJ Escherichia coli UTI89 ssDNA exonuclease RecJ YP_542256.1 3215039 R 364106 CDS YP_542257.1 91212271 3992133 complement(3216778..3217488) 1 NC_007946.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3217488 dsbC 3992133 dsbC Escherichia coli UTI89 thiol:disulfide interchange protein DsbC YP_542257.1 3216778 R 364106 CDS YP_542258.1 91212272 3992134 complement(3217513..3218409) 1 NC_007946.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3218409 xerD 3992134 xerD Escherichia coli UTI89 site-specific tyrosine recombinase XerD YP_542258.1 3217513 R 364106 CDS YP_542259.1 91212273 3992135 3218521..3219042 1 NC_007946.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3219042 fldB 3992135 fldB Escherichia coli UTI89 flavodoxin FldB YP_542259.1 3218521 D 364106 CDS YP_542260.1 91212274 3992136 complement(3219082..3219489) 1 NC_007946.1 hypothetical protein 3219489 ygfX 3992136 ygfX Escherichia coli UTI89 hypothetical protein YP_542260.1 3219082 R 364106 CDS YP_542261.1 91212275 3992137 complement(3219470..3219736) 1 NC_007946.1 hypothetical protein 3219736 ygfY 3992137 ygfY Escherichia coli UTI89 hypothetical protein YP_542261.1 3219470 R 364106 CDS YP_542262.1 91212276 3992138 3219711..3219902 1 NC_007946.1 hypothetical protein 3219902 3992138 UTI89_C3283 Escherichia coli UTI89 hypothetical protein YP_542262.1 3219711 D 364106 CDS YP_542263.1 91212277 3992139 3219979..3220959 1 NC_007946.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3220959 ygfZ 3992139 ygfZ Escherichia coli UTI89 global regulator YP_542263.1 3219979 D 364106 CDS YP_542264.1 91212278 3992140 complement(3221036..3221695) 1 NC_007946.1 oxidoreductase 3221695 3992140 UTI89_C3285 Escherichia coli UTI89 oxidoreductase YP_542264.1 3221036 R 364106 CDS YP_542265.1 91212279 3992141 complement(3221859..3222170) 1 NC_007946.1 hypothetical protein 3222170 yqfB 3992141 yqfB Escherichia coli UTI89 hypothetical protein YP_542265.1 3221859 R 364106 CDS YP_542266.1 91212280 3992142 3222191..3223648 1 NC_007946.1 6-phospho-beta-glucosidase 3223648 bglA 3992142 bglA Escherichia coli UTI89 6-phospho-beta-glucosidase YP_542266.1 3222191 D 364106 CDS YP_542267.1 91212281 3990519 complement(3223814..3226687) 1 NC_007946.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3226687 gcvP 3990519 gcvP Escherichia coli UTI89 glycine dehydrogenase YP_542267.1 3223814 R 364106 CDS YP_542268.1 91212282 3990520 complement(3226805..3227197) 1 NC_007946.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3227197 gcvH 3990520 gcvH Escherichia coli UTI89 glycine cleavage system protein H YP_542268.1 3226805 R 364106 CDS YP_542269.1 91212283 3990521 complement(3227218..3228312) 1 NC_007946.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3228312 gcvT 3990521 gcvT Escherichia coli UTI89 glycine cleavage system aminomethyltransferase T YP_542269.1 3227218 R 364106 CDS YP_542270.1 91212284 3990522 complement(3228320..3228475) 1 NC_007946.1 hypothetical protein 3228475 3990522 UTI89_C3291 Escherichia coli UTI89 hypothetical protein YP_542270.1 3228320 R 364106 CDS YP_542271.1 91212285 3990523 complement(3228760..3229962) 1 NC_007946.1 hypothetical protein 3229962 visC 3990523 visC Escherichia coli UTI89 hypothetical protein YP_542271.1 3228760 R 364106 CDS YP_542272.1 91212286 3990524 complement(3229985..3231163) 1 NC_007946.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3231163 ubiH 3990524 ubiH Escherichia coli UTI89 2-octaprenyl-6-methoxyphenyl hydroxylase YP_542272.1 3229985 R 364106 CDS YP_542273.1 91212287 3990525 complement(3231160..3232485) 1 NC_007946.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3232485 pepP 3990525 pepP Escherichia coli UTI89 proline aminopeptidase P II YP_542273.1 3231160 R 364106 CDS YP_542274.1 91212288 3990526 complement(3232511..3233095) 1 NC_007946.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3233095 ygfB 3990526 ygfB Escherichia coli UTI89 hypothetical protein YP_542274.1 3232511 R 364106 CDS YP_542275.1 91212289 3990527 3233120..3233308 1 NC_007946.1 hypothetical protein 3233308 3990527 UTI89_C3296 Escherichia coli UTI89 hypothetical protein YP_542275.1 3233120 D 364106 CDS YP_542276.1 91212290 3990528 3233257..3233586 1 NC_007946.1 Z-ring-associated protein 3233586 ygfE 3990528 ygfE Escherichia coli UTI89 Z-ring-associated protein YP_542276.1 3233257 D 364106 CDS YP_542277.1 91212291 3990529 3233688..3234434 1 NC_007946.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3234434 ygfA 3990529 ygfA Escherichia coli UTI89 ligase YP_542277.1 3233688 D 364106 CDS YP_542278.1 91212292 3990530 complement(3234824..3236056) 1 NC_007946.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3236056 serA 3990530 serA Escherichia coli UTI89 D-3-phosphoglycerate dehydrogenase YP_542278.1 3234824 R 364106 CDS YP_542279.1 91212293 3990531 complement(3236312..3237043) 1 NC_007946.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3237043 rpiA 3990531 rpiA Escherichia coli UTI89 ribose-5-phosphate isomerase A YP_542279.1 3236312 R 364106 CDS YP_542280.1 91212294 3990532 complement(3237027..3237305) 1 NC_007946.1 hypothetical protein 3237305 yqfE 3990532 yqfE Escherichia coli UTI89 hypothetical protein YP_542280.1 3237027 R 364106 CDS YP_542281.2 162138380 3990533 3237398..3238291 1 NC_007946.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3238291 iciA 3990533 iciA Escherichia coli UTI89 chromosome replication initiation inhibitor protein YP_542281.2 3237398 D 364106 CDS YP_542282.1 91212296 3990534 3238494..3239549 1 NC_007946.1 hypothetical protein 3239549 3990534 UTI89_C3303 Escherichia coli UTI89 hypothetical protein YP_542282.1 3238494 D 364106 CDS YP_542283.1 91212297 3990535 complement(3239546..3240442) 1 NC_007946.1 transcriptional regulator YgfI 3240442 ygfI 3990535 ygfI Escherichia coli UTI89 transcriptional regulator YgfI YP_542283.1 3239546 R 364106 CDS YP_542284.1 91212298 3990536 complement(3240600..3241340) 1 NC_007946.1 hypothetical protein 3241340 yggE 3990536 yggE Escherichia coli UTI89 hypothetical protein YP_542284.1 3240600 R 364106 CDS YP_542285.1 91212299 3990537 complement(3241433..3242065) 1 NC_007946.1 Involved in the export of arginine; arginine exporter protein 3242065 yggA 3990537 yggA Escherichia coli UTI89 arginine exporter protein YP_542285.1 3241433 R 364106 CDS YP_542286.1 91212300 3990538 complement(3242204..3243064) 1 NC_007946.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive ion channel MscS 3243064 yggB 3990538 yggB Escherichia coli UTI89 mechanosensitive ion channel MscS YP_542286.1 3242204 R 364106 CDS YP_542287.1 91212301 3990539 complement(3243255..3244418) 1 NC_007946.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3244418 fba 3990539 fba Escherichia coli UTI89 fructose-bisphosphate aldolase YP_542287.1 3243255 R 364106 CDS YP_542288.1 91212302 3990540 complement(3244549..3245775) 1 NC_007946.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3245775 pgk 3990540 pgk Escherichia coli UTI89 phosphoglycerate kinase YP_542288.1 3244549 R 364106 CDS YP_542289.1 91212303 3990541 complement(3245762..3246865) 1 NC_007946.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3246865 epd 3990541 epd Escherichia coli UTI89 erythrose 4-phosphate dehydrogenase YP_542289.1 3245762 R 364106 CDS YP_542290.1 91212304 3990542 3247153..3247584 1 NC_007946.1 hypothetical protein 3247584 3990542 UTI89_C3311 Escherichia coli UTI89 hypothetical protein YP_542290.1 3247153 D 364106 CDS YP_542291.1 91212305 3990543 3247607..3248185 1 NC_007946.1 hypothetical protein 3248185 3990543 UTI89_C3312 Escherichia coli UTI89 hypothetical protein YP_542291.1 3247607 D 364106 CDS YP_542292.1 91212306 3990544 3248186..3248893 1 NC_007946.1 hypothetical protein 3248893 3990544 UTI89_C3313 Escherichia coli UTI89 hypothetical protein YP_542292.1 3248186 D 364106 CDS YP_542293.1 91212307 3990545 3249022..3249558 1 NC_007946.1 ATP-binding protein of ABC transport system 3249558 3990545 UTI89_C3314 Escherichia coli UTI89 ATP-binding protein of ABC transport system YP_542293.1 3249022 D 364106 CDS YP_542294.1 91212308 3990546 3249519..3250229 1 NC_007946.1 ATP-binding protein of ABC transport system 3250229 3990546 UTI89_C3315 Escherichia coli UTI89 ATP-binding protein of ABC transport system YP_542294.1 3249519 D 364106 CDS YP_542295.1 91212309 3990547 complement(3250201..3250914) 1 NC_007946.1 fructose transport system kinase 3250914 frcK 3990547 frcK Escherichia coli UTI89 fructose transport system kinase YP_542295.1 3250201 R 364106 CDS YP_542296.1 91212310 3990548 complement(3250911..3251420) 1 NC_007946.1 DNA-binding transcriptional regulator 3251420 yggD 3990548 yggD Escherichia coli UTI89 DNA-binding transcriptional regulator YP_542296.1 3250911 R 364106 CDS YP_542297.1 91212311 3990549 complement(3251569..3251757) 1 NC_007946.1 hypothetical protein 3251757 3990549 UTI89_C3318 Escherichia coli UTI89 hypothetical protein YP_542297.1 3251569 R 364106 CDS YP_542298.1 91212312 3990550 complement(3251754..3253031) 1 NC_007946.1 oxidoreductase 3253031 3990550 UTI89_C3319 Escherichia coli UTI89 oxidoreductase YP_542298.1 3251754 R 364106 CDS YP_542299.1 91212313 3990551 complement(3253046..3254434) 1 NC_007946.1 PTS system mannitol (cryptic)-specific transporter subunit IIBC 3254434 cmtA 3990551 cmtA Escherichia coli UTI89 PTS system mannitol (cryptic)-specific transporter subunit IIBC YP_542299.1 3253046 R 364106 CDS YP_542300.1 91212314 3990552 complement(3254462..3254905) 1 NC_007946.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3254905 cmtB 3990552 cmtB Escherichia coli UTI89 mannitol phosphotransferase subunit EIIA YP_542300.1 3254462 R 364106 CDS YP_542301.1 91212315 3990553 3255282..3256190 1 NC_007946.1 SPFH domain-containing protein 3256190 3990553 UTI89_C3322 Escherichia coli UTI89 SPFH domain-containing protein YP_542301.1 3255282 D 364106 CDS YP_542302.2 162138379 3990554 complement(3256410..3258401) 1 NC_007946.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3258401 tktA 3990554 tktA Escherichia coli UTI89 transketolase YP_542302.2 3256410 R 364106 CDS YP_542303.1 91212317 3990555 3258460..3259437 1 NC_007946.1 metalloprotease YggG 3259437 yggG 3990555 yggG Escherichia coli UTI89 metalloprotease YggG YP_542303.1 3258460 D 364106 CDS YP_542304.1 91212318 3990556 complement(3259641..3260561) 1 NC_007946.1 catalyzes the formation of putrescine from agmatine; agmatinase 3260561 speB 3990556 speB Escherichia coli UTI89 agmatinase YP_542304.1 3259641 R 364106 CDS YP_542305.1 91212319 3990557 complement(3260697..3261428) 1 NC_007946.1 hypothetical protein 3261428 3990557 UTI89_C3326 Escherichia coli UTI89 hypothetical protein YP_542305.1 3260697 R 364106 CDS YP_542306.1 91212320 3992658 complement(3261574..3263562) 1 NC_007946.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3263562 speA 3992658 speA Escherichia coli UTI89 arginine decarboxylase YP_542306.1 3261574 R 364106 CDS YP_542307.1 91212321 3992659 complement(3263559..3263705) 1 NC_007946.1 hypothetical protein 3263705 yqgB 3992659 yqgB Escherichia coli UTI89 hypothetical protein YP_542307.1 3263559 R 364106 CDS YP_542308.1 91212322 3992660 3263826..3264041 1 NC_007946.1 hypothetical protein 3264041 yqgC 3992660 yqgC Escherichia coli UTI89 hypothetical protein YP_542308.1 3263826 D 364106 CDS YP_542309.1 91212323 3992661 complement(3264038..3264304) 1 NC_007946.1 hypothetical protein 3264304 yqgD 3992661 yqgD Escherichia coli UTI89 hypothetical protein YP_542309.1 3264038 R 364106 CDS YP_542310.2 162138378 3992662 3264345..3265499 1 NC_007946.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3265499 metK 3992662 metK Escherichia coli UTI89 S-adenosylmethionine synthetase YP_542310.2 3264345 D 364106 CDS YP_542311.1 91212325 3992663 3265924..3267330 1 NC_007946.1 galactose-proton symporter 3267330 galP 3992663 galP Escherichia coli UTI89 galactose-proton symporter YP_542311.1 3265924 D 364106 CDS YP_542312.1 91212326 3992664 3267407..3267904 1 NC_007946.1 hypothetical protein 3267904 sprT 3992664 sprT Escherichia coli UTI89 hypothetical protein YP_542312.1 3267407 D 364106 CDS YP_542313.1 91212327 3992665 3267996..3268706 1 NC_007946.1 endonuclease I 3268706 endA 3992665 endA Escherichia coli UTI89 endonuclease I YP_542313.1 3267996 D 364106 CDS YP_542314.2 162138377 3992666 3268786..3269517 1 NC_007946.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3269517 yggJ 3992666 yggJ Escherichia coli UTI89 16S ribosomal RNA methyltransferase RsmE YP_542314.2 3268786 D 364106 CDS YP_542315.1 91212329 3992667 3269530..3270480 1 NC_007946.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3270480 gshB 3992667 gshB Escherichia coli UTI89 glutathione synthetase YP_542315.1 3269530 D 364106 CDS YP_542316.1 91212330 3992668 3270517..3271152 1 NC_007946.1 hypothetical protein 3271152 yqgE 3992668 yqgE Escherichia coli UTI89 hypothetical protein YP_542316.1 3270517 D 364106 CDS YP_542317.1 91212331 3992669 3271152..3271568 1 NC_007946.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3271568 3992669 UTI89_C3338 Escherichia coli UTI89 Holliday junction resolvase-like protein YP_542317.1 3271152 D 364106 CDS YP_542318.1 91212332 3992670 complement(3271742..3272797) 1 NC_007946.1 hypothetical protein 3272797 yggR 3992670 yggR Escherichia coli UTI89 hypothetical protein YP_542318.1 3271742 R 364106 CDS YP_542319.1 91212333 3992671 3272740..3273444 1 NC_007946.1 hypothetical protein 3273444 yggS 3992671 yggS Escherichia coli UTI89 hypothetical protein YP_542319.1 3272740 D 364106 CDS YP_542320.1 91212334 3992672 3273462..3274028 1 NC_007946.1 resistance protein 3274028 yggT 3992672 yggT Escherichia coli UTI89 resistance protein YP_542320.1 3273462 D 364106 CDS YP_542321.1 91212335 3992673 3274013..3274315 1 NC_007946.1 hypothetical protein 3274315 yggU 3992673 yggU Escherichia coli UTI89 hypothetical protein YP_542321.1 3274013 D 364106 CDS YP_542322.1 91212336 3992674 3274323..3274916 1 NC_007946.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3274916 yggV 3992674 yggV Escherichia coli UTI89 deoxyribonucleotide triphosphate pyrophosphatase YP_542322.1 3274323 D 364106 CDS YP_542323.1 91212337 3992675 3274909..3276045 1 NC_007946.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3276045 yggW 3992675 yggW Escherichia coli UTI89 coproporphyrinogen III oxidase YP_542323.1 3274909 D 364106 CDS YP_542324.1 91212338 3992676 complement(3276114..3277121) 1 NC_007946.1 hypothetical protein 3277121 yggM 3992676 yggM Escherichia coli UTI89 hypothetical protein YP_542324.1 3276114 R 364106 CDS YP_542325.1 91212339 3992912 complement(3277238..3278284) 1 NC_007946.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3278284 ansB 3992912 ansB Escherichia coli UTI89 L-asparaginase II YP_542325.1 3277238 R 364106 CDS YP_542326.1 91212340 3992913 complement(3278460..3279179) 1 NC_007946.1 hypothetical protein 3279179 yggN 3992913 yggN Escherichia coli UTI89 hypothetical protein YP_542326.1 3278460 R 364106 CDS YP_542327.1 91212341 3992914 complement(3279200..3279340) 1 NC_007946.1 hypothetical protein 3279340 3992914 UTI89_C3348 Escherichia coli UTI89 hypothetical protein YP_542327.1 3279200 R 364106 CDS YP_542328.2 162138376 3992915 complement(3279363..3279689) 1 NC_007946.1 hypothetical protein 3279689 yggL 3992915 yggL Escherichia coli UTI89 hypothetical protein YP_542328.2 3279363 R 364106 CDS YP_542329.1 91212343 3992916 complement(3279689..3280408) 1 NC_007946.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3280408 trmB 3992916 trmB Escherichia coli UTI89 tRNA (guanine-N(7)-)-methyltransferase YP_542329.1 3279689 R 364106 CDS YP_542330.1 91212344 3992917 3280539..3281621 1 NC_007946.1 adenine DNA glycosylase 3281621 mutY 3992917 mutY Escherichia coli UTI89 adenine DNA glycosylase YP_542330.1 3280539 D 364106 CDS YP_542331.1 91212345 3992918 complement(3281598..3281891) 1 NC_007946.1 hypothetical protein 3281891 3992918 UTI89_C3352 Escherichia coli UTI89 hypothetical protein YP_542331.1 3281598 R 364106 CDS YP_542332.1 91212346 3992919 3281649..3281924 1 NC_007946.1 hypothetical protein 3281924 yggX 3992919 yggX Escherichia coli UTI89 hypothetical protein YP_542332.1 3281649 D 364106 CDS YP_542333.1 91212347 3992920 3281986..3283068 1 NC_007946.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3283068 mltC 3992920 mltC Escherichia coli UTI89 murein transglycosylase C YP_542333.1 3281986 D 364106 CDS YP_542334.1 91212348 3992921 3283222..3284526 1 NC_007946.1 transport of nucleosides, permease 3284526 nupG 3992921 nupG Escherichia coli UTI89 transport of nucleosides, permease YP_542334.1 3283222 D 364106 CDS YP_542335.1 91212349 3992922 complement(3284575..3286710) 1 NC_007946.1 ornithine decarboxylase 3286710 speC 3992922 speC Escherichia coli UTI89 ornithine decarboxylase YP_542335.1 3284575 R 364106 CDS YP_542336.1 91212350 3992923 complement(3286791..3286994) 1 NC_007946.1 hypothetical protein 3286994 3992923 UTI89_C3357 Escherichia coli UTI89 hypothetical protein YP_542336.1 3286791 R 364106 CDS YP_542337.1 91212351 3992924 3287109..3287816 1 NC_007946.1 hypothetical protein 3287816 yqgA 3992924 yqgA Escherichia coli UTI89 hypothetical protein YP_542337.1 3287109 D 364106 CDS YP_542338.1 91212352 3992926 3288222..3288377 1 NC_007946.1 hypothetical protein 3288377 3992926 UTI89_C3360 Escherichia coli UTI89 hypothetical protein YP_542338.1 3288222 D 364106 CDS YP_542339.1 91212353 3992927 complement(3288545..3288688) 1 NC_007946.1 hypothetical protein 3288688 3992927 UTI89_C3361 Escherichia coli UTI89 hypothetical protein YP_542339.1 3288545 R 364106 CDS YP_542340.1 91212354 3992928 3289151..3290170 1 NC_007946.1 polysialic acid capsule synthesis protein KpsF 3290170 kpsF 3992928 kpsF Escherichia coli UTI89 polysialic acid capsule synthesis protein KpsF YP_542340.1 3289151 D 364106 CDS YP_542341.1 91212355 3992929 3290242..3291390 1 NC_007946.1 polysialic acid capsule synthesis protein KpsE 3291390 kpsE 3992929 kpsE Escherichia coli UTI89 polysialic acid capsule synthesis protein KpsE YP_542341.1 3290242 D 364106 CDS YP_542342.1 91212356 3992930 3291411..3293090 1 NC_007946.1 polysialic acid transport protein KpsD 3293090 kpsD 3992930 kpsD Escherichia coli UTI89 polysialic acid transport protein KpsD YP_542342.1 3291411 D 364106 CDS YP_542343.1 91212357 3991873 3293100..3293840 1 NC_007946.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3293840 kpsU 3991873 kpsU Escherichia coli UTI89 3-deoxy-manno-octulosonate cytidylyltransferase YP_542343.1 3293100 D 364106 CDS YP_542344.1 91212358 3991874 3293837..3295864 1 NC_007946.1 capsule polysaccharide export protein KpsC 3295864 kpsC 3991874 kpsC Escherichia coli UTI89 capsule polysaccharide export protein KpsC YP_542344.1 3293837 D 364106 CDS YP_542345.1 91212359 3991875 3295899..3297104 1 NC_007946.1 polysialic acid capsule synthesis protein KpsS 3297104 kpsS 3991875 kpsS Escherichia coli UTI89 polysialic acid capsule synthesis protein KpsS YP_542345.1 3295899 D 364106 CDS YP_542346.1 91212360 3991876 complement(3297254..3298483) 1 NC_007946.1 poly-alpha-2,8 sialosyl sialyltransferase 3298483 neuS 3991876 neuS Escherichia coli UTI89 poly-alpha-2,8 sialosyl sialyltransferase YP_542346.1 3297254 R 364106 CDS YP_542347.1 91212361 3991877 complement(3298473..3299621) 1 NC_007946.1 NeuE protein 3299621 neuE 3991877 neuE Escherichia coli UTI89 NeuE protein YP_542347.1 3298473 R 364106 CDS YP_542348.1 91212362 3991878 complement(3299614..3300789) 1 NC_007946.1 polysialic acid biosynthesis protein P7 3300789 neuC 3991878 neuC Escherichia coli UTI89 polysialic acid biosynthesis protein P7 YP_542348.1 3299614 R 364106 CDS YP_542349.1 91212363 3991879 complement(3300786..3302042) 1 NC_007946.1 acylneuraminate cytidylyltransferase 3302042 neuA 3991879 neuA Escherichia coli UTI89 acylneuraminate cytidylyltransferase YP_542349.1 3300786 R 364106 CDS YP_542350.1 91212364 3991880 complement(3302042..3303082) 1 NC_007946.1 sialic acid synthase NeuB 3303082 neuB 3991880 neuB Escherichia coli UTI89 sialic acid synthase NeuB YP_542350.1 3302042 R 364106 CDS YP_542351.1 91212365 3991881 complement(3303079..3303702) 1 NC_007946.1 sialic acid synthase NeuD 3303702 neuD 3991881 neuD Escherichia coli UTI89 sialic acid synthase NeuD YP_542351.1 3303079 R 364106 CDS YP_542352.1 91212366 3991882 complement(3303752..3304411) 1 NC_007946.1 polysialic acid transport ATP-binding protein kpsT 3304411 kpsT 3991882 kpsT Escherichia coli UTI89 polysialic acid transport ATP-binding protein kpsT YP_542352.1 3303752 R 364106 CDS YP_542353.1 91212367 3991883 complement(3304408..3305184) 1 NC_007946.1 polysialic acid transport protein KpsM 3305184 kpsM 3991883 kpsM Escherichia coli UTI89 polysialic acid transport protein KpsM YP_542353.1 3304408 R 364106 CDS YP_542354.1 91212368 3991884 complement(3306242..3306778) 1 NC_007946.1 general secretion pathway protein YghD 3306778 gspM 3991884 gspM Escherichia coli UTI89 general secretion pathway protein YghD YP_542354.1 3306242 R 364106 CDS YP_542355.2 162138375 3991885 complement(3306780..3307640) 1 NC_007946.1 similar to general secretory pathway protein L; GspL-like protein 3307640 gspL 3991885 gspL Escherichia coli UTI89 GspL-like protein YP_542355.2 3306780 R 364106 CDS YP_542356.1 91212370 3991886 complement(3307955..3308932) 1 NC_007946.1 hypothetical protein 3308932 gspK 3991886 gspK Escherichia coli UTI89 hypothetical protein YP_542356.1 3307955 R 364106 CDS YP_542357.1 91212371 3991887 complement(3308929..3309498) 1 NC_007946.1 type II secretion protein GspJ 3309498 gspJ 3991887 gspJ Escherichia coli UTI89 type II secretion protein GspJ YP_542357.1 3308929 R 364106 CDS YP_542358.1 91212372 3991888 complement(3309531..3309902) 1 NC_007946.1 type II secretion protein GspI 3309902 gspI 3991888 gspI Escherichia coli UTI89 type II secretion protein GspI YP_542358.1 3309531 R 364106 CDS YP_542359.1 91212373 3991889 complement(3309899..3310462) 1 NC_007946.1 type II secretion protein GspH 3310462 gspH 3991889 gspH Escherichia coli UTI89 type II secretion protein GspH YP_542359.1 3309899 R 364106 CDS YP_542360.1 91212374 3991890 complement(3310466..3310921) 1 NC_007946.1 type II secretion protein GspG 3310921 gspG 3991890 gspG Escherichia coli UTI89 type II secretion protein GspG YP_542360.1 3310466 R 364106 CDS YP_542361.1 91212375 3991891 complement(3310938..3312161) 1 NC_007946.1 type II secretion protein GspF 3312161 gspF 3991891 gspF Escherichia coli UTI89 type II secretion protein GspF YP_542361.1 3310938 R 364106 CDS YP_542362.1 91212376 3991951 complement(3312161..3313654) 1 NC_007946.1 type II secretion protein GspE 3313654 gspE 3991951 gspE Escherichia coli UTI89 type II secretion protein GspE YP_542362.1 3312161 R 364106 CDS YP_542363.1 91212377 3991952 complement(3313654..3315714) 1 NC_007946.1 type II secretion protein GspD 3315714 gspD 3991952 gspD Escherichia coli UTI89 type II secretion protein GspD YP_542363.1 3313654 R 364106 CDS YP_542364.1 91212378 3991953 complement(3315744..3316574) 1 NC_007946.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC 3316574 gspC 3991953 gspC Escherichia coli UTI89 type II secretion protein GspC YP_542364.1 3315744 R 364106 CDS YP_542365.1 91212379 3991954 complement(3316721..3317131) 1 NC_007946.1 lipoprotein 3317131 yghG 3991954 yghG Escherichia coli UTI89 lipoprotein YP_542365.1 3316721 R 364106 CDS YP_542366.1 91212380 3991955 complement(3317197..3318006) 1 NC_007946.1 prepilin peptidase A 3318006 pppA 3991955 pppA Escherichia coli UTI89 prepilin peptidase A YP_542366.1 3317197 R 364106 CDS YP_542367.1 91212381 3991956 complement(3318170..3322732) 1 NC_007946.1 lipoprotein AcfD-like 3322732 yghJ 3991956 yghJ Escherichia coli UTI89 lipoprotein AcfD-like YP_542367.1 3318170 R 364106 CDS YP_542368.1 91212382 3991957 3322883..3323188 1 NC_007946.1 hypothetical protein 3323188 3991957 UTI89_C3390 Escherichia coli UTI89 hypothetical protein YP_542368.1 3322883 D 364106 CDS YP_542369.1 91212383 3991958 complement(3323216..3324898) 1 NC_007946.1 glycolate transporter 3324898 glcA 3991958 glcA Escherichia coli UTI89 glycolate transporter YP_542369.1 3323216 R 364106 CDS YP_542370.1 91212384 3991959 complement(3325254..3327425) 1 NC_007946.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3327425 glcB 3991959 glcB Escherichia coli UTI89 malate synthase G YP_542370.1 3325254 R 364106 CDS YP_542371.1 91212385 3991960 complement(3327447..3327869) 1 NC_007946.1 hypothetical protein 3327869 glcG 3991960 glcG Escherichia coli UTI89 hypothetical protein YP_542371.1 3327447 R 364106 CDS YP_542372.1 91212386 3991961 complement(3330142..3331641) 1 NC_007946.1 glycolate oxidase subunit GlcD 3331641 glcD 3991961 glcD Escherichia coli UTI89 glycolate oxidase subunit GlcD YP_542372.1 3330142 R 364106 CDS YP_542373.1 91212387 3991962 3331832..3332656 1 NC_007946.1 DNA-binding transcriptional regulator GlcC 3332656 glcC 3991962 glcC Escherichia coli UTI89 DNA-binding transcriptional regulator GlcC YP_542373.1 3331832 D 364106 CDS YP_542374.1 91212388 3991963 complement(3332663..3333805) 1 NC_007946.1 hypothetical protein 3333805 3991963 UTI89_C3396 Escherichia coli UTI89 hypothetical protein YP_542374.1 3332663 R 364106 CDS YP_542375.1 91212389 3991964 3334167..3335900 1 NC_007946.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3335900 3991964 UTI89_C3397 Escherichia coli UTI89 acyl-CoA synthetase YP_542375.1 3334167 D 364106 CDS YP_542376.1 91212390 3991965 3335897..3336811 1 NC_007946.1 hypothetical protein 3336811 3991965 UTI89_C3398 Escherichia coli UTI89 hypothetical protein YP_542376.1 3335897 D 364106 CDS YP_542377.1 91212391 3991966 3336843..3337091 1 NC_007946.1 acyl carrier protein 3337091 3991966 UTI89_C3399 Escherichia coli UTI89 acyl carrier protein YP_542377.1 3336843 D 364106 CDS YP_542378.1 91212392 3991967 3337091..3338263 1 NC_007946.1 hypothetical protein 3338263 3991967 UTI89_C3400 Escherichia coli UTI89 hypothetical protein YP_542378.1 3337091 D 364106 CDS YP_542379.1 91212393 3991968 complement(3338298..3339458) 1 NC_007946.1 hypothetical protein 3339458 3991968 UTI89_C3401 Escherichia coli UTI89 hypothetical protein YP_542379.1 3338298 R 364106 CDS YP_542380.1 91212394 3991969 complement(3339374..3340444) 1 NC_007946.1 hypothetical protein 3340444 3991969 UTI89_C3402 Escherichia coli UTI89 hypothetical protein YP_542380.1 3339374 R 364106 CDS YP_542381.1 91212395 3991970 complement(3340475..3341035) 1 NC_007946.1 protein YtfJ 3341035 3991970 UTI89_C3403 Escherichia coli UTI89 protein YtfJ YP_542381.1 3340475 R 364106 CDS YP_542382.1 91212396 3994462 complement(3341035..3341871) 1 NC_007946.1 hypothetical protein 3341871 3994462 UTI89_C3404 Escherichia coli UTI89 hypothetical protein YP_542382.1 3341035 R 364106 CDS YP_542383.1 91212397 3994463 complement(3341871..3343220) 1 NC_007946.1 hypothetical protein 3343220 yghQ 3994463 yghQ Escherichia coli UTI89 hypothetical protein YP_542383.1 3341871 R 364106 CDS YP_542384.1 91212398 3994464 complement(3343266..3344036) 1 NC_007946.1 hypothetical protein 3344036 yghR 3994464 yghR Escherichia coli UTI89 hypothetical protein YP_542384.1 3343266 R 364106 CDS YP_542385.1 91212399 3994465 complement(3344056..3344769) 1 NC_007946.1 ATP-binding protein YghS 3344769 yghS 3994465 yghS Escherichia coli UTI89 ATP-binding protein YghS YP_542385.1 3344056 R 364106 CDS YP_542386.1 91212400 3994466 3344944..3345636 1 NC_007946.1 ATP-binding protein YghT 3345636 yghT 3994466 yghT Escherichia coli UTI89 ATP-binding protein YghT YP_542386.1 3344944 D 364106 CDS YP_542387.1 91212401 3994467 complement(3345685..3347184) 1 NC_007946.1 inorganic phosphate transporter 3347184 pitB 3994467 pitB Escherichia coli UTI89 inorganic phosphate transporter YP_542387.1 3345685 R 364106 CDS YP_542388.1 91212402 3994468 complement(3347476..3349338) 1 NC_007946.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3349338 gsp 3994468 gsp Escherichia coli UTI89 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_542388.1 3347476 R 364106 CDS YP_542389.1 91212403 3994469 3349492..3350406 1 NC_007946.1 YghU; B2989; one of eight glutathione transferases from E. coli; glutathione S-transferase YghU 3350406 yghU 3994469 yghU Escherichia coli UTI89 glutathione S-transferase YghU YP_542389.1 3349492 D 364106 CDS YP_542390.1 91212404 3994470 complement(3350539..3350787) 1 NC_007946.1 hydrogenase 2 accessory protein HypG 3350787 hybG 3994470 hybG Escherichia coli UTI89 hydrogenase 2 accessory protein HypG YP_542390.1 3350539 R 364106 CDS YP_542391.1 91212405 3994471 complement(3350800..3351141) 1 NC_007946.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3351141 hybF 3994471 hybF Escherichia coli UTI89 hydrogenase nickel incorporation protein HybF YP_542391.1 3350800 R 364106 CDS YP_542392.1 91212406 3994472 complement(3351134..3351622) 1 NC_007946.1 hydrogenase 2-specific chaperone 3351622 hybE 3994472 hybE Escherichia coli UTI89 hydrogenase 2-specific chaperone YP_542392.1 3351134 R 364106 CDS YP_542393.1 91212407 3994473 complement(3351615..3352109) 1 NC_007946.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3352109 hybD 3994473 hybD Escherichia coli UTI89 hydrogenase 2 maturation endopeptidase YP_542393.1 3351615 R 364106 CDS YP_542394.1 91212408 3994474 complement(3352109..3353812) 1 NC_007946.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3353812 hybC 3994474 hybC Escherichia coli UTI89 hydrogenase 2 large subunit YP_542394.1 3352109 R 364106 CDS YP_542395.1 91212409 3994475 complement(3353809..3354987) 1 NC_007946.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3354987 hybB 3994475 hybB Escherichia coli UTI89 hydrogenase 2 b cytochrome subunit YP_542395.1 3353809 R 364106 CDS YP_542396.1 91212410 3994476 complement(3354977..3355963) 1 NC_007946.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3355963 hybA 3994476 hybA Escherichia coli UTI89 hydrogenase 2 protein HybA YP_542396.1 3354977 R 364106 CDS YP_542397.1 91212411 3994477 complement(3355966..3357084) 1 NC_007946.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3357084 3994477 UTI89_C3419 Escherichia coli UTI89 hydrogenase 2 small subunit YP_542397.1 3355966 R 364106 CDS YP_542398.1 91212412 3994478 complement(3357273..3357560) 1 NC_007946.1 hypothetical protein 3357560 yghW 3994478 yghW Escherichia coli UTI89 hypothetical protein YP_542398.1 3357273 R 364106 CDS YP_542399.1 91212413 3994479 complement(3357679..3358605) 1 NC_007946.1 hypothetical protein 3358605 3994479 UTI89_C3421 Escherichia coli UTI89 hypothetical protein YP_542399.1 3357679 R 364106 CDS YP_542400.1 91212414 3994480 3358723..3359763 1 NC_007946.1 aldo/keto reductase 3359763 yghZ 3994480 yghZ Escherichia coli UTI89 aldo/keto reductase YP_542400.1 3358723 D 364106 CDS YP_542401.1 91212415 3991461 complement(3359803..3360327) 1 NC_007946.1 hypothetical protein 3360327 yqhA 3991461 yqhA Escherichia coli UTI89 hypothetical protein YP_542401.1 3359803 R 364106 CDS YP_542402.1 91212416 3991462 3360485..3361372 1 NC_007946.1 oxidoreductase 3361372 yghA 3991462 yghA Escherichia coli UTI89 oxidoreductase YP_542402.1 3360485 D 364106 CDS YP_542403.1 91212417 3991463 complement(3361411..3361836) 1 NC_007946.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3361836 exbD 3991463 exbD Escherichia coli UTI89 biopolymer transport protein ExbD YP_542403.1 3361411 R 364106 CDS YP_542404.1 91212418 3991464 complement(3361843..3362577) 1 NC_007946.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3362577 exbB 3991464 exbB Escherichia coli UTI89 biopolymer transport protein ExbB YP_542404.1 3361843 R 364106 CDS YP_542405.1 91212419 3991465 complement(3362570..3362725) 1 NC_007946.1 hypothetical protein 3362725 3991465 UTI89_C3427 Escherichia coli UTI89 hypothetical protein YP_542405.1 3362570 R 364106 CDS YP_542406.1 91212420 3991466 3362694..3364016 1 NC_007946.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3364016 metC 3991466 metC Escherichia coli UTI89 cystathionine beta-lyase YP_542406.1 3362694 D 364106 CDS YP_542407.1 91212421 3991467 3364156..3364815 1 NC_007946.1 hypothetical protein 3364815 yghB 3991467 yghB Escherichia coli UTI89 hypothetical protein YP_542407.1 3364156 D 364106 CDS YP_542408.1 91212422 3991468 complement(3364855..3365982) 1 NC_007946.1 transcriptional regulator YqhC 3365982 yqhC 3991468 yqhC Escherichia coli UTI89 transcriptional regulator YqhC YP_542408.1 3364855 R 364106 CDS YP_542409.1 91212423 3991469 3365948..3367111 1 NC_007946.1 oxidoreductase YqhD 3367111 yqhD 3991469 yqhD Escherichia coli UTI89 oxidoreductase YqhD YP_542409.1 3365948 D 364106 CDS YP_542410.1 91212424 3991470 3367216..3368043 1 NC_007946.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3368043 dkgA 3991470 dkgA Escherichia coli UTI89 2,5-diketo-D-gluconate reductase A YP_542410.1 3367216 D 364106 CDS YP_542411.1 91212425 3991471 3368243..3369169 1 NC_007946.1 hypothetical protein 3369169 yqhG 3991471 yqhG Escherichia coli UTI89 hypothetical protein YP_542411.1 3368243 D 364106 CDS YP_542412.1 91212426 3991472 3369220..3369477 1 NC_007946.1 outer membrane lipoprotein 3369477 yqhH 3991472 yqhH Escherichia coli UTI89 outer membrane lipoprotein YP_542412.1 3369220 D 364106 CDS YP_542413.1 91212427 3991473 complement(3369519..3371738) 1 NC_007946.1 hypothetical protein 3371738 3991473 UTI89_C3435 Escherichia coli UTI89 hypothetical protein YP_542413.1 3369519 R 364106 CDS YP_542414.1 91212428 3991474 3371990..3372739 1 NC_007946.1 regulator 3372739 3991474 UTI89_C3436 Escherichia coli UTI89 regulator YP_542414.1 3371990 D 364106 CDS YP_542415.1 91212429 3991475 3373026..3374534 1 NC_007946.1 oxidoreductase YdfI 3374534 3991475 UTI89_C3437 Escherichia coli UTI89 oxidoreductase YdfI YP_542415.1 3373026 D 364106 CDS YP_542416.1 91212430 3991476 3374531..3375547 1 NC_007946.1 zinc-type alcohol dehydrogenase-like protein YjjN 3375547 3991476 UTI89_C3438 Escherichia coli UTI89 zinc-type alcohol dehydrogenase-like protein YjjN YP_542416.1 3374531 D 364106 CDS YP_542417.1 91212431 3991477 3375558..3376568 1 NC_007946.1 ureidoglycolate dehydrogenase 3376568 3991477 UTI89_C3439 Escherichia coli UTI89 ureidoglycolate dehydrogenase YP_542417.1 3375558 D 364106 CDS YP_542418.1 91212432 3991478 3376641..3377624 1 NC_007946.1 c4-dicarboxylate transport system binding protein 3377624 3991478 UTI89_C3440 Escherichia coli UTI89 c4-dicarboxylate transport system binding protein YP_542418.1 3376641 D 364106 CDS YP_542419.1 91212433 3991479 3377666..3378148 1 NC_007946.1 hypothetical protein 3378148 3991479 UTI89_C3441 Escherichia coli UTI89 hypothetical protein YP_542419.1 3377666 D 364106 CDS YP_542420.1 91212434 3991480 3378117..3379463 1 NC_007946.1 c4-dicarboxylate permease 3379463 ygiK 3991480 ygiK Escherichia coli UTI89 c4-dicarboxylate permease YP_542420.1 3378117 D 364106 CDS YP_542421.1 91212435 3991815 complement(3379534..3380946) 1 NC_007946.1 repressor protein for FtsI 3380946 sufI 3991815 sufI Escherichia coli UTI89 repressor protein for FtsI YP_542421.1 3379534 R 364106 CDS YP_542422.1 91212436 3991816 complement(3381021..3381758) 1 NC_007946.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 3381758 plsC 3991816 plsC Escherichia coli UTI89 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_542422.1 3381021 R 364106 CDS YP_542423.1 91212437 3991817 complement(3381807..3381962) 1 NC_007946.1 hypothetical protein 3381962 3991817 UTI89_C3445 Escherichia coli UTI89 hypothetical protein YP_542423.1 3381807 R 364106 CDS YP_542424.1 91212438 3991818 complement(3381993..3384251) 1 NC_007946.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3384251 parC 3991818 parC Escherichia coli UTI89 DNA topoisomerase IV subunit A YP_542424.1 3381993 R 364106 CDS YP_542425.1 91212439 3991819 complement(3384389..3386059) 1 NC_007946.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; binding protein 3386059 3991819 UTI89_C3447 Escherichia coli UTI89 binding protein YP_542425.1 3384389 R 364106 CDS YP_542426.1 91212440 3991820 complement(3386105..3386587) 1 NC_007946.1 hypothetical protein 3386587 ygiV 3991820 ygiV Escherichia coli UTI89 hypothetical protein YP_542426.1 3386105 R 364106 CDS YP_542427.1 91212441 3991821 complement(3386640..3387089) 1 NC_007946.1 hypothetical protein 3387089 ygiW 3991821 ygiW Escherichia coli UTI89 hypothetical protein YP_542427.1 3386640 R 364106 CDS YP_542428.1 91212442 3991822 3387184..3387843 1 NC_007946.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3387843 ygiX 3991822 ygiX Escherichia coli UTI89 DNA-binding transcriptional regulator QseB YP_542428.1 3387184 D 364106 CDS YP_542429.1 91212443 3991823 3387840..3389189 1 NC_007946.1 synonym: b3026, ygiO, G7576, ygiY; sensor protein QseC 3389189 qseC 3991823 qseC Escherichia coli UTI89 sensor protein QseC YP_542429.1 3387840 D 364106 CDS YP_542430.1 91212444 3991824 complement(3389235..3389567) 1 NC_007946.1 hypothetical protein 3389567 3991824 UTI89_C3452 Escherichia coli UTI89 hypothetical protein YP_542430.1 3389235 R 364106 CDS YP_542431.1 91212445 3991825 complement(3389574..3390311) 1 NC_007946.1 hypothetical protein 3390311 3991825 UTI89_C3453 Escherichia coli UTI89 hypothetical protein YP_542431.1 3389574 R 364106 CDS YP_542432.1 91212446 3991826 complement(3390287..3390766) 1 NC_007946.1 hypothetical protein 3390766 3991826 UTI89_C3454 Escherichia coli UTI89 hypothetical protein YP_542432.1 3390287 R 364106 CDS YP_542433.1 91212447 3991827 3391016..3391597 1 NC_007946.1 modulator of drug activity B 3391597 mdaB 3991827 mdaB Escherichia coli UTI89 modulator of drug activity B YP_542433.1 3391016 D 364106 CDS YP_542434.1 91212448 3991828 complement(3391622..3391945) 1 NC_007946.1 hypothetical protein 3391945 3991828 UTI89_C3456 Escherichia coli UTI89 hypothetical protein YP_542434.1 3391622 R 364106 CDS YP_542435.1 91212449 3991829 3391628..3391942 1 NC_007946.1 protein YgiN 3391942 ygiN 3991829 ygiN Escherichia coli UTI89 protein YgiN YP_542435.1 3391628 D 364106 CDS YP_542436.1 91212450 3991830 complement(3391987..3392874) 1 NC_007946.1 hypothetical protein 3392874 3991830 UTI89_C3458 Escherichia coli UTI89 hypothetical protein YP_542436.1 3391987 R 364106 CDS YP_542437.1 91212451 3991831 complement(3392871..3393881) 1 NC_007946.1 iron ABC transporter substrate-binding protein 3393881 3991831 UTI89_C3459 Escherichia coli UTI89 iron ABC transporter substrate-binding protein YP_542437.1 3392871 R 364106 CDS YP_542438.1 91212452 3991832 complement(3393829..3394878) 1 NC_007946.1 iron ABC transporter permease 3394878 3991832 UTI89_C3460 Escherichia coli UTI89 iron ABC transporter permease YP_542438.1 3393829 R 364106 CDS YP_542439.1 91212453 3991833 complement(3394875..3395858) 1 NC_007946.1 iron ABC transporter permease 3395858 3991833 UTI89_C3461 Escherichia coli UTI89 iron ABC transporter permease YP_542439.1 3394875 R 364106 CDS YP_542440.1 91212454 3993158 complement(3395855..3396664) 1 NC_007946.1 ferric enterobactin transport ATP-binding protein fepC 3396664 3993158 UTI89_C3462 Escherichia coli UTI89 ferric enterobactin transport ATP-binding protein fepC YP_542440.1 3395855 R 364106 CDS YP_542441.1 91212455 3993159 3397038..3399179 1 NC_007946.1 iron compound receptor 3399179 3993159 UTI89_C3463 Escherichia coli UTI89 iron compound receptor YP_542441.1 3397038 D 364106 CDS YP_542442.1 91212456 3993160 complement(3399243..3401135) 1 NC_007946.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3401135 parE 3993160 parE Escherichia coli UTI89 DNA topoisomerase IV subunit B YP_542442.1 3399243 R 364106 CDS YP_542443.1 91212457 3993161 complement(3401164..3401745) 1 NC_007946.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 3401745 yqiA 3993161 yqiA Escherichia coli UTI89 esterase YP_542443.1 3401164 R 364106 CDS YP_542444.1 91212458 3993162 complement(3401745..3402572) 1 NC_007946.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 3402572 icc 3993162 icc Escherichia coli UTI89 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_542444.1 3401745 R 364106 CDS YP_542445.1 91212459 3993163 complement(3402597..3403019) 1 NC_007946.1 hypothetical protein 3403019 yqiB 3993163 yqiB Escherichia coli UTI89 hypothetical protein YP_542445.1 3402597 R 364106 CDS YP_542446.1 91212460 3993164 complement(3403020..3403649) 1 NC_007946.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase 3403649 nudF 3993164 nudF Escherichia coli UTI89 ADP-ribose pyrophosphatase YP_542446.1 3403020 R 364106 CDS YP_542447.1 91212461 3993165 3403815..3405335 1 NC_007946.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3405335 tolC 3993165 tolC Escherichia coli UTI89 outer membrane channel protein YP_542447.1 3403815 D 364106 CDS YP_542448.1 91212462 3993166 3405332..3405595 1 NC_007946.1 hypothetical protein 3405595 ygiA 3993166 ygiA Escherichia coli UTI89 hypothetical protein YP_542448.1 3405332 D 364106 CDS YP_542449.2 162138374 3993167 3405483..3406154 1 NC_007946.1 hypothetical protein 3406154 ygiB 3993167 ygiB Escherichia coli UTI89 hypothetical protein YP_542449.2 3405483 D 364106 CDS YP_542450.1 91212464 3993168 3406160..3407320 1 NC_007946.1 synthetase/amidase 3407320 ygiC 3993168 ygiC Escherichia coli UTI89 synthetase/amidase YP_542450.1 3406160 D 364106 CDS YP_542451.1 91212465 3993169 3407805..3409601 1 NC_007946.1 arylsulfate sulfotransferase 3409601 asst 3993169 asst Escherichia coli UTI89 arylsulfate sulfotransferase YP_542451.1 3407805 D 364106 CDS YP_542452.1 91212466 3993170 3409619..3410287 1 NC_007946.1 disulfide isomerase 3410287 3993170 UTI89_C3474 Escherichia coli UTI89 disulfide isomerase YP_542452.1 3409619 D 364106 CDS YP_542453.1 91212467 3993171 3410302..3410973 1 NC_007946.1 disulfide oxidoreductase 3410973 3993171 UTI89_C3475 Escherichia coli UTI89 disulfide oxidoreductase YP_542453.1 3410302 D 364106 CDS YP_542454.1 91212468 3993172 complement(3411019..3411834) 1 NC_007946.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3411834 ygiD 3993172 ygiD Escherichia coli UTI89 hypothetical protein YP_542454.1 3411019 R 364106 CDS YP_542455.1 91212469 3993173 3411908..3412723 1 NC_007946.1 synonym: ygiE, b3040; zinc transporter ZupT 3412723 zupT 3993173 zupT Escherichia coli UTI89 zinc transporter ZupT YP_542455.1 3411908 D 364106 CDS YP_542456.1 91212470 3993174 complement(3412785..3412970) 1 NC_007946.1 hypothetical protein 3412970 3993174 UTI89_C3478 Escherichia coli UTI89 hypothetical protein YP_542456.1 3412785 R 364106 CDS YP_542457.1 91212471 3993175 3413527..3414090 1 NC_007946.1 fimbrial protein 3414090 ygiL 3993175 ygiL Escherichia coli UTI89 fimbrial protein YP_542457.1 3413527 D 364106 CDS YP_542458.1 91212472 3993176 3414177..3416699 1 NC_007946.1 outer membrane usher protein YqiG 3416699 yqiG 3993176 yqiG Escherichia coli UTI89 outer membrane usher protein YqiG YP_542458.1 3414177 D 364106 CDS YP_542459.1 91212473 3993177 3416706..3417455 1 NC_007946.1 periplasmic chaperone YqiH 3417455 yqiH 3993177 yqiH Escherichia coli UTI89 periplasmic chaperone YqiH YP_542459.1 3416706 D 364106 CDS YP_542460.1 91212474 3993888 3417452..3418501 1 NC_007946.1 Yqi fimbrial adhesin 3418501 3993888 UTI89_C3482 Escherichia coli UTI89 Yqi fimbrial adhesin YP_542460.1 3417452 D 364106 CDS YP_542461.1 91212475 3993889 complement(3418555..3419208) 1 NC_007946.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3419208 ribB 3993889 ribB Escherichia coli UTI89 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_542461.1 3418555 R 364106 CDS YP_542462.1 91212476 3993890 3419522..3419881 1 NC_007946.1 hypothetical protein 3419881 yqiC 3993890 yqiC Escherichia coli UTI89 hypothetical protein YP_542462.1 3419522 D 364106 CDS YP_542463.1 91212477 3993891 complement(3419916..3420122) 1 NC_007946.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3420122 glgS 3993891 glgS Escherichia coli UTI89 glycogen synthesis protein GlgS YP_542463.1 3419916 R 364106 CDS YP_542464.1 91212478 3993892 3420386..3421015 1 NC_007946.1 hypothetical protein 3421015 yqiJ 3993892 yqiJ Escherichia coli UTI89 hypothetical protein YP_542464.1 3420386 D 364106 CDS YP_542465.1 91212479 3993893 3421042..3422703 1 NC_007946.1 hypothetical protein 3422703 yqiK 3993893 yqiK Escherichia coli UTI89 hypothetical protein YP_542465.1 3421042 D 364106 CDS YP_542466.1 91212480 3993894 complement(3423122..3424555) 1 NC_007946.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3424555 3993894 UTI89_C3488 Escherichia coli UTI89 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_542466.1 3423122 R 364106 CDS YP_542467.2 162138373 3993895 complement(3424603..3427443) 1 NC_007946.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3427443 glnE 3993895 glnE Escherichia coli UTI89 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_542467.2 3424603 R 364106 CDS YP_542468.1 91212482 3993896 complement(3427466..3428767) 1 NC_007946.1 hypothetical protein 3428767 ygiF 3993896 ygiF Escherichia coli UTI89 hypothetical protein YP_542468.1 3427466 R 364106 CDS YP_542469.1 91212483 3993897 3429009..3429629 1 NC_007946.1 signal transduction protein 3429629 ygiM 3993897 ygiM Escherichia coli UTI89 signal transduction protein YP_542469.1 3429009 D 364106 CDS YP_542470.1 91212484 3993898 3429693..3430931 1 NC_007946.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3430931 cca 3993898 cca Escherichia coli UTI89 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_542470.1 3429693 D 364106 CDS YP_542471.1 91212485 3993899 complement(3431119..3431943) 1 NC_007946.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3431943 bacA 3993899 bacA Escherichia coli UTI89 undecaprenyl pyrophosphate phosphatase YP_542471.1 3431119 R 364106 CDS YP_542472.1 91212486 3993900 complement(3432031..3432402) 1 NC_007946.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3432402 folB 3993900 folB Escherichia coli UTI89 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_542472.1 3432031 R 364106 CDS YP_542473.1 91212487 3993901 3432504..3433121 1 NC_007946.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3433121 ygiH 3993901 ygiH Escherichia coli UTI89 glycerol-3-phosphate acyltransferase PlsY YP_542473.1 3432504 D 364106 CDS YP_542474.1 91212488 3993902 complement(3433134..3434114) 1 NC_007946.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3434114 ygiP 3993902 ygiP Escherichia coli UTI89 transcriptional activator TtdR YP_542474.1 3433134 R 364106 CDS YP_542475.1 91212489 3993903 3434273..3435184 1 NC_007946.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3435184 ttdA 3993903 ttdA Escherichia coli UTI89 tartrate dehydratase subunit alpha YP_542475.1 3434273 D 364106 CDS YP_542476.1 91212490 3993904 3435181..3435786 1 NC_007946.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3435786 ttdB 3993904 ttdB Escherichia coli UTI89 L(+)-tartrate dehydratase subunit beta YP_542476.1 3435181 D 364106 CDS YP_542477.1 91212491 3993905 3435834..3437297 1 NC_007946.1 tartrate carrier/transporter 3437297 ygjE 3993905 ygjE Escherichia coli UTI89 tartrate carrier/transporter YP_542477.1 3435834 D 364106 CDS YP_542478.1 91212492 3993906 complement(3437340..3438353) 1 NC_007946.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3438353 ygjD 3993906 ygjD Escherichia coli UTI89 DNA-binding/iron metalloprotein/AP endonuclease YP_542478.1 3437340 R 364106 CDS YP_542479.1 91212493 3992143 complement(3438362..3438649) 1 NC_007946.1 hypothetical protein 3438649 3992143 UTI89_C3501 Escherichia coli UTI89 hypothetical protein YP_542479.1 3438362 R 364106 CDS YP_542480.1 91212494 3992144 3438591..3438806 1 NC_007946.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3438806 rpsU 3992144 rpsU Escherichia coli UTI89 30S ribosomal protein S21 YP_542480.1 3438591 D 364106 CDS YP_542481.1 91212495 3992145 3438917..3440662 1 NC_007946.1 synthesizes RNA primers at the replication forks; DNA primase 3440662 dnaG 3992145 dnaG Escherichia coli UTI89 DNA primase YP_542481.1 3438917 D 364106 CDS YP_542482.1 91212496 3992146 3440676..3440798 1 NC_007946.1 hypothetical protein 3440798 3992146 UTI89_C3504 Escherichia coli UTI89 hypothetical protein YP_542482.1 3440676 D 364106 CDS YP_542483.1 91212497 3992147 3440857..3442698 1 NC_007946.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3442698 rpoD 3992147 rpoD Escherichia coli UTI89 RNA polymerase sigma factor RpoD YP_542483.1 3440857 D 364106 CDS YP_542484.1 91212498 3992148 complement(3442777..3443283) 1 NC_007946.1 G/U mismatch-specific DNA glycosylase 3443283 ygjF 3992148 ygjF Escherichia coli UTI89 G/U mismatch-specific DNA glycosylase YP_542484.1 3442777 R 364106 CDS YP_542485.1 91212499 3992150 complement(3443537..3444301) 1 NC_007946.1 hypothetical protein 3444301 yqjH 3992150 yqjH Escherichia coli UTI89 hypothetical protein YP_542485.1 3443537 R 364106 CDS YP_542486.1 91212500 3992151 3444578..3445201 1 NC_007946.1 hypothetical protein 3445201 yqjI 3992151 yqjI Escherichia coli UTI89 hypothetical protein YP_542486.1 3444578 D 364106 CDS YP_542487.1 91212501 3992152 complement(3445355..3446875) 1 NC_007946.1 aerotaxis sensor receptor, flavoprotein 3446875 aer 3992152 aer Escherichia coli UTI89 aerotaxis sensor receptor, flavoprotein YP_542487.1 3445355 R 364106 CDS YP_542488.2 162138372 3992153 3447266..3448672 1 NC_007946.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3448672 ygjG 3992153 ygjG Escherichia coli UTI89 putrescine--2-oxoglutarate aminotransferase YP_542488.2 3447266 D 364106 CDS YP_542489.1 91212503 3992154 3448656..3449066 1 NC_007946.1 hypothetical protein 3449066 3992154 UTI89_C3512 Escherichia coli UTI89 hypothetical protein YP_542489.1 3448656 D 364106 CDS YP_542490.1 91212504 3992155 complement(3448714..3449046) 1 NC_007946.1 hypothetical protein 3449046 ygjH 3992155 ygjH Escherichia coli UTI89 hypothetical protein YP_542490.1 3448714 R 364106 CDS YP_542491.1 91212505 3992156 3449153..3449335 1 NC_007946.1 hypothetical protein 3449335 3992156 UTI89_C3514 Escherichia coli UTI89 hypothetical protein YP_542491.1 3449153 D 364106 CDS YP_542492.1 91212506 3992157 3449265..3450248 1 NC_007946.1 DNA-binding transcriptional repressor EbgR 3450248 ebgR 3992157 ebgR Escherichia coli UTI89 DNA-binding transcriptional repressor EbgR YP_542492.1 3449265 D 364106 CDS YP_542493.1 91212507 3992158 3450255..3453524 1 NC_007946.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3453524 ebgA 3992158 ebgA Escherichia coli UTI89 cryptic beta-D-galactosidase subunit alpha YP_542493.1 3450255 D 364106 CDS YP_542494.1 91212508 3992159 3453521..3453970 1 NC_007946.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3453970 ebgC 3992159 ebgC Escherichia coli UTI89 cryptic beta-D-galactosidase subunit beta YP_542494.1 3453521 D 364106 CDS YP_542495.1 91212509 3992160 3454033..3455466 1 NC_007946.1 oxidoreductase 3455466 ygjI 3992160 ygjI Escherichia coli UTI89 oxidoreductase YP_542495.1 3454033 D 364106 CDS YP_542496.1 91212510 3992161 3455600..3456670 1 NC_007946.1 hypothetical protein 3456670 ygjJ 3992161 ygjJ Escherichia coli UTI89 hypothetical protein YP_542496.1 3455600 D 364106 CDS YP_542497.1 91212511 3990113 3456687..3459038 1 NC_007946.1 glycosyl hydrolase 3459038 ygjK 3990113 ygjK Escherichia coli UTI89 glycosyl hydrolase YP_542497.1 3456687 D 364106 CDS YP_542498.1 91212512 3990114 3459209..3461227 1 NC_007946.1 NADPH 2,4-dienoyl-CoA reductase 3461227 ygjL 3990114 ygjL Escherichia coli UTI89 NADPH 2,4-dienoyl-CoA reductase YP_542498.1 3459209 D 364106 CDS YP_542499.1 91212513 3990115 complement(3461345..3462481) 1 NC_007946.1 ribosomal RNA small subunit methyltransferase D 3462481 ygjO 3990115 ygjO Escherichia coli UTI89 ribosomal RNA small subunit methyltransferase D YP_542499.1 3461345 R 364106 CDS YP_542500.1 91212514 3990116 3462530..3463069 1 NC_007946.1 hypothetical protein 3463069 ygjP 3990116 ygjP Escherichia coli UTI89 hypothetical protein YP_542500.1 3462530 D 364106 CDS YP_542501.1 91212515 3990117 3463137..3463838 1 NC_007946.1 hypothetical protein 3463838 ygjQ 3990117 ygjQ Escherichia coli UTI89 hypothetical protein YP_542501.1 3463137 D 364106 CDS YP_542502.1 91212516 3990118 3463899..3464903 1 NC_007946.1 oxidoreductase YgjR 3464903 ygjR 3990118 ygjR Escherichia coli UTI89 oxidoreductase YgjR YP_542502.1 3463899 D 364106 CDS YP_542503.1 91212517 3990119 3465186..3466151 1 NC_007946.1 hypothetical protein 3466151 ygjT 3990119 ygjT Escherichia coli UTI89 hypothetical protein YP_542503.1 3465186 D 364106 CDS YP_542504.1 91212518 3990120 3466475..3467719 1 NC_007946.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3467719 ygjU 3990120 ygjU Escherichia coli UTI89 serine/threonine transporter SstT YP_542504.1 3466475 D 364106 CDS YP_542505.1 91212519 3990121 complement(3467723..3468274) 1 NC_007946.1 hypothetical protein 3468274 ygjV 3990121 ygjV Escherichia coli UTI89 hypothetical protein YP_542505.1 3467723 R 364106 CDS YP_542506.1 91212520 3990122 complement(3468357..3469844) 1 NC_007946.1 altronate hydrolase 3469844 uxaA 3990122 uxaA Escherichia coli UTI89 altronate hydrolase YP_542506.1 3468357 R 364106 CDS YP_542507.1 91212521 3990123 complement(3469859..3471334) 1 NC_007946.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3471334 uxaC 3990123 uxaC Escherichia coli UTI89 glucuronate isomerase YP_542507.1 3469859 R 364106 CDS YP_542508.1 91212522 3990124 3471634..3473052 1 NC_007946.1 hexuronate transporter 3473052 exuT 3990124 exuT Escherichia coli UTI89 hexuronate transporter YP_542508.1 3471634 D 364106 CDS YP_542509.2 162138371 3990125 3473182..3473958 1 NC_007946.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3473958 exuR 3990125 exuR Escherichia coli UTI89 DNA-binding transcriptional repressor ExuR YP_542509.2 3473182 D 364106 CDS YP_542510.1 91212524 3990126 3474303..3474965 1 NC_007946.1 hypothetical protein 3474965 yqjA 3990126 yqjA Escherichia coli UTI89 hypothetical protein YP_542510.1 3474303 D 364106 CDS YP_542511.1 91212525 3990127 3474969..3475352 1 NC_007946.1 hypothetical protein 3475352 yqjB 3990127 yqjB Escherichia coli UTI89 hypothetical protein YP_542511.1 3474969 D 364106 CDS YP_542512.1 91212526 3990128 3475484..3475867 1 NC_007946.1 hypothetical protein 3475867 yqjC 3990128 yqjC Escherichia coli UTI89 hypothetical protein YP_542512.1 3475484 D 364106 CDS YP_542513.1 91212527 3990129 3475905..3476210 1 NC_007946.1 hypothetical protein 3476210 yqjD 3990129 yqjD Escherichia coli UTI89 hypothetical protein YP_542513.1 3475905 D 364106 CDS YP_542514.1 91212528 3990130 3476213..3476617 1 NC_007946.1 hypothetical protein 3476617 yqjE 3990130 yqjE Escherichia coli UTI89 hypothetical protein YP_542514.1 3476213 D 364106 CDS YP_542515.1 91212529 3990131 3476607..3476906 1 NC_007946.1 hypothetical protein 3476906 yqjK 3990131 yqjK Escherichia coli UTI89 hypothetical protein YP_542515.1 3476607 D 364106 CDS YP_542516.1 91212530 3990310 3477081..3477485 1 NC_007946.1 hypothetical protein 3477485 yqjF 3990310 yqjF Escherichia coli UTI89 hypothetical protein YP_542516.1 3477081 D 364106 CDS YP_542517.1 91212531 3990311 3477555..3478541 1 NC_007946.1 transferase 3478541 yqjG 3990311 yqjG Escherichia coli UTI89 transferase YP_542517.1 3477555 D 364106 CDS YP_542518.1 91212532 3990312 3478803..3479192 1 NC_007946.1 hypothetical protein 3479192 yhaH 3990312 yhaH Escherichia coli UTI89 hypothetical protein YP_542518.1 3478803 D 364106 CDS YP_542519.1 91212533 3990313 complement(3479226..3480122) 1 NC_007946.1 transcriptional regulator YhaJ 3480122 yhaJ 3990313 yhaJ Escherichia coli UTI89 transcriptional regulator YhaJ YP_542519.1 3479226 R 364106 CDS YP_542520.1 91212534 3990314 3480227..3480928 1 NC_007946.1 hypothetical protein 3480928 yhaK 3990314 yhaK Escherichia coli UTI89 hypothetical protein YP_542520.1 3480227 D 364106 CDS YP_542521.1 91212535 3990315 3480945..3481115 1 NC_007946.1 hypothetical protein 3481115 yhaL 3990315 yhaL Escherichia coli UTI89 hypothetical protein YP_542521.1 3480945 D 364106 CDS YP_542522.1 91212536 3990316 complement(3481247..3482557) 1 NC_007946.1 hypothetical protein 3482557 3990316 UTI89_C3545 Escherichia coli UTI89 hypothetical protein YP_542522.1 3481247 R 364106 CDS YP_542523.1 91212537 3990317 complement(3482585..3483916) 1 NC_007946.1 transport system permease 3483916 yhaO 3990317 yhaO Escherichia coli UTI89 transport system permease YP_542523.1 3482585 R 364106 CDS YP_542524.1 91212538 3990318 complement(3484191..3485561) 1 NC_007946.1 L-serine dehydratase 1 3485561 tdcG 3990318 tdcG Escherichia coli UTI89 L-serine dehydratase 1 YP_542524.1 3484191 R 364106 CDS YP_542525.1 91212539 3990319 complement(3485627..3486079) 1 NC_007946.1 hypothetical protein 3486079 yhaR 3990319 yhaR Escherichia coli UTI89 hypothetical protein YP_542525.1 3485627 R 364106 CDS YP_542526.1 91212540 3990320 complement(3486030..3488324) 1 NC_007946.1 keto-acid formate acetyltransferase 3488324 tdcE 3990320 tdcE Escherichia coli UTI89 keto-acid formate acetyltransferase YP_542526.1 3486030 R 364106 CDS YP_542527.1 91212541 3990321 complement(3488358..3489578) 1 NC_007946.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3489578 tdcD 3990321 tdcD Escherichia coli UTI89 propionate/acetate kinase YP_542527.1 3488358 R 364106 CDS YP_542528.1 91212542 3990322 complement(3489592..3490923) 1 NC_007946.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3490923 tdcC 3990322 tdcC Escherichia coli UTI89 threonine/serine transporter TdcC YP_542528.1 3489592 R 364106 CDS YP_542529.1 91212543 3990323 complement(3490945..3491934) 1 NC_007946.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3491934 tdcB 3990323 tdcB Escherichia coli UTI89 threonine dehydratase YP_542529.1 3490945 R 364106 CDS YP_542530.1 91212544 3990324 complement(3492033..3492971) 1 NC_007946.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3492971 tdcA 3990324 tdcA Escherichia coli UTI89 DNA-binding transcriptional activator TdcA YP_542530.1 3492033 R 364106 CDS YP_542531.2 162138370 3990325 3493161..3493505 1 NC_007946.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3493505 tdcR 3990325 tdcR Escherichia coli UTI89 DNA-binding transcriptional activator TdcR YP_542531.2 3493161 D 364106 CDS YP_542532.1 91212546 3990326 complement(3494479..3495705) 1 NC_007946.1 glycerate kinase I 3495705 yhaD 3990326 yhaD Escherichia coli UTI89 glycerate kinase I YP_542532.1 3494479 R 364106 CDS YP_542533.2 162138369 3990327 complement(3495721..3496611) 1 NC_007946.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3496611 garR 3990327 garR Escherichia coli UTI89 tartronate semialdehyde reductase YP_542533.2 3495721 R 364106 CDS YP_542534.1 91212548 3990328 complement(3496641..3497411) 1 NC_007946.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3497411 yhaF 3990328 yhaF Escherichia coli UTI89 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_542534.1 3496641 R 364106 CDS YP_542535.1 91212549 3990329 complement(3497427..3498761) 1 NC_007946.1 galactarate transporter 3498761 yhaU 3990329 yhaU Escherichia coli UTI89 galactarate transporter YP_542535.1 3497427 R 364106 CDS YP_542536.1 91212550 3992470 3499136..3500707 1 NC_007946.1 synonym: b3128, yhaG; D-galactarate dehydratase 3500707 garD 3992470 garD Escherichia coli UTI89 D-galactarate dehydratase YP_542536.1 3499136 D 364106 CDS YP_542537.1 91212551 3992471 complement(3500759..3501583) 1 NC_007946.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3501583 agaR 3992471 agaR Escherichia coli UTI89 DNA-binding transcriptional regulator AgaR YP_542537.1 3500759 R 364106 CDS YP_542538.1 91212552 3992472 3501832..3503112 1 NC_007946.1 tagatose 6-phosphate kinase 2 3503112 agaZ 3992472 agaZ Escherichia coli UTI89 tagatose 6-phosphate kinase 2 YP_542538.1 3501832 D 364106 CDS YP_542539.1 91212553 3992473 3503099..3503608 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3503608 agaV 3992473 agaV Escherichia coli UTI89 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_542539.1 3503099 D 364106 CDS YP_542540.1 91212554 3992474 3503619..3504398 1 NC_007946.1 phosphotransferase system enzyme subunit 3504398 3992474 UTI89_C3563 Escherichia coli UTI89 phosphotransferase system enzyme subunit YP_542540.1 3503619 D 364106 CDS YP_542541.1 91212555 3992475 3504382..3505266 1 NC_007946.1 PTS system N-acetylgalactosamine-specific transporter subunit IID 3505266 3992475 UTI89_C3564 Escherichia coli UTI89 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_542541.1 3504382 D 364106 CDS YP_542542.1 91212556 3992476 3505284..3505718 1 NC_007946.1 phosphotransferase system enzyme subunit 3505718 3992476 UTI89_C3565 Escherichia coli UTI89 phosphotransferase system enzyme subunit YP_542542.1 3505284 D 364106 CDS YP_542543.1 91212557 3992477 3505694..3506848 1 NC_007946.1 N-acetylgalctosamine-6-phosphate deacetylase 3506848 3992477 UTI89_C3566 Escherichia coli UTI89 N-acetylgalctosamine-6-phosphate deacetylase YP_542543.1 3505694 D 364106 CDS YP_542544.1 91212558 3992478 3507197..3508351 1 NC_007946.1 tagatose-6-phosphate ketose/aldose isomerase 3508351 agaS 3992478 agaS Escherichia coli UTI89 tagatose-6-phosphate ketose/aldose isomerase YP_542544.1 3507197 D 364106 CDS YP_542545.1 91212559 3992479 3508364..3509224 1 NC_007946.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3509224 kbaY 3992479 kbaY Escherichia coli UTI89 tagatose-bisphosphate aldolase YP_542545.1 3508364 D 364106 CDS YP_542546.1 91212560 3992480 3509391..3509867 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3509867 agaB 3992480 agaB Escherichia coli UTI89 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_542546.1 3509391 D 364106 CDS YP_542547.1 91212561 3992481 3509906..3510709 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3510709 agaC 3992481 agaC Escherichia coli UTI89 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_542547.1 3509906 D 364106 CDS YP_542548.1 91212562 3992482 3510630..3511490 1 NC_007946.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3511490 agaD 3992482 agaD Escherichia coli UTI89 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_542548.1 3510630 D 364106 CDS YP_542549.1 91212563 3992483 3511491..3512258 1 NC_007946.1 galactosamine-6-phosphate isomerase 3512258 agaI 3992483 agaI Escherichia coli UTI89 galactosamine-6-phosphate isomerase YP_542549.1 3511491 D 364106 CDS YP_542550.1 91212564 3992484 complement(3512308..3513171) 1 NC_007946.1 hypothetical protein 3513171 yraL 3992484 yraL Escherichia coli UTI89 hypothetical protein YP_542550.1 3512308 R 364106 CDS YP_542551.1 91212565 3992485 3515230..3515625 1 NC_007946.1 hypothetical protein 3515625 yraN 3992485 yraN Escherichia coli UTI89 hypothetical protein YP_542551.1 3515230 D 364106 CDS YP_542552.1 91212566 3992486 complement(3515494..3515619) 1 NC_007946.1 hypothetical protein 3515619 3992486 UTI89_C3575 Escherichia coli UTI89 hypothetical protein YP_542552.1 3515494 R 364106 CDS YP_542553.1 91212567 3992487 3515645..3516235 1 NC_007946.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; chromosome replication initiator DnaA 3516235 yraO 3992487 yraO Escherichia coli UTI89 chromosome replication initiator DnaA YP_542553.1 3515645 D 364106 CDS YP_542554.1 91212568 3992488 3516245..3516820 1 NC_007946.1 hypothetical protein 3516820 yraP 3992488 yraP Escherichia coli UTI89 hypothetical protein YP_542554.1 3516245 D 364106 CDS YP_542555.1 91212569 3990631 complement(3516933..3517973) 1 NC_007946.1 hypothetical protein 3517973 yraQ 3990631 yraQ Escherichia coli UTI89 hypothetical protein YP_542555.1 3516933 R 364106 CDS YP_542556.1 91212570 3990632 complement(3518046..3518681) 1 NC_007946.1 hypothetical protein 3518681 yraR 3990632 yraR Escherichia coli UTI89 hypothetical protein YP_542556.1 3518046 R 364106 CDS YP_542557.1 91212571 3990633 3518767..3519327 1 NC_007946.1 hypothetical protein 3519327 yhbO 3990633 yhbO Escherichia coli UTI89 hypothetical protein YP_542557.1 3518767 D 364106 CDS YP_542558.1 91212572 3990634 complement(3519307..3519750) 1 NC_007946.1 hypothetical protein 3519750 yhbP 3990634 yhbP Escherichia coli UTI89 hypothetical protein YP_542558.1 3519307 R 364106 CDS YP_542559.1 91212573 3990635 3519801..3520103 1 NC_007946.1 GIY-YIG nuclease superfamily protein 3520103 yhbQ 3990635 yhbQ Escherichia coli UTI89 GIY-YIG nuclease superfamily protein YP_542559.1 3519801 D 364106 CDS YP_542560.1 91212574 3990636 complement(3520090..3520593) 1 NC_007946.1 acetyltransferase YhbS 3520593 yhbS 3990636 yhbS Escherichia coli UTI89 acetyltransferase YhbS YP_542560.1 3520090 R 364106 CDS YP_542561.1 91212575 3990637 complement(3520587..3521135) 1 NC_007946.1 hypothetical protein 3521135 yhbT 3990637 yhbT Escherichia coli UTI89 hypothetical protein YP_542561.1 3520587 R 364106 CDS YP_542562.1 91212576 3990638 3521293..3522315 1 NC_007946.1 protease YhbU 3522315 yhbU 3990638 yhbU Escherichia coli UTI89 protease YhbU YP_542562.1 3521293 D 364106 CDS YP_542563.1 91212577 3990639 3522306..3523202 1 NC_007946.1 hypothetical protein 3523202 yhbV 3990639 yhbV Escherichia coli UTI89 hypothetical protein YP_542563.1 3522306 D 364106 CDS YP_542564.1 91212578 3990640 3523283..3524290 1 NC_007946.1 hypothetical protein 3524290 yhbW 3990640 yhbW Escherichia coli UTI89 hypothetical protein YP_542564.1 3523283 D 364106 CDS YP_542565.1 91212579 3990641 complement(3524408..3525652) 1 NC_007946.1 tryptophan transporter of high affinity; tryptophan permease 3525652 mtr 3990641 mtr Escherichia coli UTI89 tryptophan permease YP_542565.1 3524408 R 364106 CDS YP_542566.1 91212580 3990642 3525668..3525805 1 NC_007946.1 hypothetical protein 3525805 3990642 UTI89_C3589 Escherichia coli UTI89 hypothetical protein YP_542566.1 3525668 D 364106 CDS YP_542567.2 162138368 3990643 complement(3525806..3527695) 1 NC_007946.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3527695 deaD 3990643 deaD Escherichia coli UTI89 ATP-dependent RNA helicase DeaD YP_542567.2 3525806 R 364106 CDS YP_542568.1 91212582 3990644 3527832..3527990 1 NC_007946.1 hypothetical protein 3527990 3990644 UTI89_C3591 Escherichia coli UTI89 hypothetical protein YP_542568.1 3527832 D 364106 CDS YP_542569.1 91212583 3990645 complement(3527875..3528759) 1 NC_007946.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3528759 nlpI 3990645 nlpI Escherichia coli UTI89 lipoprotein NlpI YP_542569.1 3527875 R 364106 CDS YP_542570.1 91212584 3990646 3528805..3531027 1 NC_007946.1 hypothetical protein 3531027 3990646 UTI89_C3593 Escherichia coli UTI89 hypothetical protein YP_542570.1 3528805 D 364106 CDS YP_542571.1 91212585 3990647 complement(3528868..3531090) 1 NC_007946.1 polynucleotide phosphorylase 3531090 pnp 3990647 pnp Escherichia coli UTI89 polynucleotide phosphorylase YP_542571.1 3528868 R 364106 CDS YP_542572.1 91212586 3990648 complement(3531250..3531519) 1 NC_007946.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3531519 rpsO 3990648 rpsO Escherichia coli UTI89 30S ribosomal protein S15 YP_542572.1 3531250 R 364106 CDS YP_542573.1 91212587 3990649 complement(3531668..3532612) 1 NC_007946.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3532612 truB 3990649 truB Escherichia coli UTI89 tRNA pseudouridine synthase B YP_542573.1 3531668 R 364106 CDS YP_542574.2 162138367 3990650 complement(3532612..3533013) 1 NC_007946.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3533013 rbfA 3990650 rbfA Escherichia coli UTI89 ribosome-binding factor A YP_542574.2 3532612 R 364106 CDS YP_542575.1 91212589 3994745 complement(3533177..3535849) 1 NC_007946.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3535849 infB 3994745 infB Escherichia coli UTI89 translation initiation factor IF-2 YP_542575.1 3533177 R 364106 CDS YP_542576.1 91212590 3994746 3535706..3537175 1 NC_007946.1 hypothetical protein 3537175 3994746 UTI89_C3599 Escherichia coli UTI89 hypothetical protein YP_542576.1 3535706 D 364106 CDS YP_542577.1 91212591 3994747 complement(3535874..3537361) 1 NC_007946.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3537361 nusA 3994747 nusA Escherichia coli UTI89 transcription elongation factor NusA YP_542577.1 3535874 R 364106 CDS YP_542578.1 91212592 3994748 complement(3537389..3537853) 1 NC_007946.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3537853 yhbC 3994748 yhbC Escherichia coli UTI89 hypothetical protein YP_542578.1 3537389 R 364106 CDS YP_542580.1 91212594 3994751 3538472..3539815 1 NC_007946.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3539815 argG 3994751 argG Escherichia coli UTI89 argininosuccinate synthase YP_542580.1 3538472 D 364106 CDS YP_542581.1 91212595 3994752 complement(3539823..3541481) 1 NC_007946.1 outer membrane protein YhbX 3541481 yhbX 3994752 yhbX Escherichia coli UTI89 outer membrane protein YhbX YP_542581.1 3539823 R 364106 CDS YP_542582.2 162138366 3994754 complement(3542003..3542335) 1 NC_007946.1 preprotein translocase subunit SecG 3542335 secG 3994754 secG Escherichia coli UTI89 preprotein translocase subunit SecG YP_542582.2 3542003 R 364106 CDS YP_542583.1 91212597 3994755 complement(3542563..3543900) 1 NC_007946.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3543900 glmM 3994755 glmM Escherichia coli UTI89 phosphoglucosamine mutase YP_542583.1 3542563 R 364106 CDS YP_542584.2 162138365 3994756 complement(3543893..3544741) 1 NC_007946.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3544741 folP 3994756 folP Escherichia coli UTI89 dihydropteroate synthase YP_542584.2 3543893 R 364106 CDS YP_542585.1 91212599 3994757 complement(3544831..3546765) 1 NC_007946.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3546765 hflB 3994757 hflB Escherichia coli UTI89 ATP-dependent metalloprotease YP_542585.1 3544831 R 364106 CDS YP_542586.1 91212600 3994758 complement(3546865..3547494) 1 NC_007946.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 3547494 rrmJ 3994758 rrmJ Escherichia coli UTI89 23S rRNA methyltransferase YP_542586.1 3546865 R 364106 CDS YP_542587.1 91212601 3994759 complement(3547550..3547852) 1 NC_007946.1 hypothetical protein 3547852 3994759 UTI89_C3612 Escherichia coli UTI89 hypothetical protein YP_542587.1 3547550 R 364106 CDS YP_542588.1 91212602 3994760 3547620..3547913 1 NC_007946.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3547913 yhbY 3994760 yhbY Escherichia coli UTI89 RNA-binding protein YhbY YP_542588.1 3547620 D 364106 CDS YP_542589.1 91212603 3994761 complement(3548069..3548545) 1 NC_007946.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3548545 greA 3994761 greA Escherichia coli UTI89 transcription elongation factor GreA YP_542589.1 3548069 R 364106 CDS YP_542590.1 91212604 3994096 3548793..3550226 1 NC_007946.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3550226 dacB 3994096 dacB Escherichia coli UTI89 D-alanyl-D-alanine carboxypeptidase/endopeptidase YP_542590.1 3548793 D 364106 CDS YP_542591.1 91212605 3994097 complement(3550267..3551427) 1 NC_007946.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3551427 obgE 3994097 obgE Escherichia coli UTI89 GTPase ObgE YP_542591.1 3550267 R 364106 CDS YP_542592.1 91212606 3994098 complement(3551443..3552408) 1 NC_007946.1 transport protein YhbE 3552408 yhbE 3994098 yhbE Escherichia coli UTI89 transport protein YhbE YP_542592.1 3551443 R 364106 CDS YP_542593.1 91212607 3994099 complement(3552535..3552792) 1 NC_007946.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3552792 rpmA 3994099 rpmA Escherichia coli UTI89 50S ribosomal protein L27 YP_542593.1 3552535 R 364106 CDS YP_542594.1 91212608 3994100 3552786..3553331 1 NC_007946.1 hypothetical protein 3553331 3994100 UTI89_C3619 Escherichia coli UTI89 hypothetical protein YP_542594.1 3552786 D 364106 CDS YP_542595.1 91212609 3994101 complement(3552813..3553124) 1 NC_007946.1 50S ribosomal protein L21 3553124 rplU 3994101 rplU Escherichia coli UTI89 50S ribosomal protein L21 YP_542595.1 3552813 R 364106 CDS YP_542596.1 91212610 3994102 3553383..3554354 1 NC_007946.1 octaprenyl diphosphate synthase 3554354 ispB 3994102 ispB Escherichia coli UTI89 octaprenyl diphosphate synthase YP_542596.1 3553383 D 364106 CDS YP_542597.1 91212611 3994103 3554587..3554865 1 NC_007946.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3554865 nlp 3994103 nlp Escherichia coli UTI89 DNA-binding transcriptional regulator Nlp YP_542597.1 3554587 D 364106 CDS YP_542598.1 91212612 3994104 complement(3554913..3556172) 1 NC_007946.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3556172 murA 3994104 murA Escherichia coli UTI89 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_542598.1 3554913 R 364106 CDS YP_542599.1 91212613 3994105 complement(3556227..3556496) 1 NC_007946.1 hypothetical protein 3556496 yrbA 3994105 yrbA Escherichia coli UTI89 hypothetical protein YP_542599.1 3556227 R 364106 CDS YP_542600.1 91212614 3994106 3556293..3556634 1 NC_007946.1 hypothetical protein 3556634 3994106 UTI89_C3625 Escherichia coli UTI89 hypothetical protein YP_542600.1 3556293 D 364106 CDS YP_542601.1 91212615 3994107 complement(3556641..3557030) 1 NC_007946.1 hypothetical protein 3557030 yrbB 3994107 yrbB Escherichia coli UTI89 hypothetical protein YP_542601.1 3556641 R 364106 CDS YP_542602.1 91212616 3994108 3556922..3557557 1 NC_007946.1 hypothetical protein 3557557 3994108 UTI89_C3627 Escherichia coli UTI89 hypothetical protein YP_542602.1 3556922 D 364106 CDS YP_542603.1 91212617 3994109 complement(3556934..3557569) 1 NC_007946.1 hypothetical protein 3557569 yrbC 3994109 yrbC Escherichia coli UTI89 hypothetical protein YP_542603.1 3556934 R 364106 CDS YP_542604.1 91212618 3994110 complement(3557588..3558154) 1 NC_007946.1 hypothetical protein 3558154 yrbD 3994110 yrbD Escherichia coli UTI89 hypothetical protein YP_542604.1 3557588 R 364106 CDS YP_542605.1 91212619 3994111 complement(3558144..3558926) 1 NC_007946.1 hypothetical protein 3558926 yrbE 3994111 yrbE Escherichia coli UTI89 hypothetical protein YP_542605.1 3558144 R 364106 CDS YP_542606.1 91212620 3994112 complement(3558934..3559743) 1 NC_007946.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF 3559743 yrbF 3994112 yrbF Escherichia coli UTI89 ABC transporter ATP-binding protein YrbF YP_542606.1 3558934 R 364106 CDS YP_542607.1 91212621 3994113 3559953..3560930 1 NC_007946.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3560930 yrbG 3994113 yrbG Escherichia coli UTI89 calcium/sodium:proton antiporter YP_542607.1 3559953 D 364106 CDS YP_542608.1 91212622 3994114 3560923..3561930 1 NC_007946.1 D-arabinose 5-phosphate isomerase 3561930 yrbH 3994114 yrbH Escherichia coli UTI89 D-arabinose 5-phosphate isomerase YP_542608.1 3560923 D 364106 CDS YP_542609.1 91212623 3994115 3561951..3562517 1 NC_007946.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3562517 yrbI 3994115 yrbI Escherichia coli UTI89 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_542609.1 3561951 D 364106 CDS YP_542610.1 91212624 3993793 3562514..3563089 1 NC_007946.1 hypothetical protein 3563089 yrbK 3993793 yrbK Escherichia coli UTI89 hypothetical protein YP_542610.1 3562514 D 364106 CDS YP_542611.1 91212625 3993794 3563037..3563615 1 NC_007946.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3563615 yhbN 3993794 yhbN Escherichia coli UTI89 lipopolysaccharide transport periplasmic protein LptA YP_542611.1 3563037 D 364106 CDS YP_542612.1 91212626 3993795 3563622..3564347 1 NC_007946.1 ABC transporter ATP-binding protein YhbG 3564347 yhbG 3993795 yhbG Escherichia coli UTI89 ABC transporter ATP-binding protein YhbG YP_542612.1 3563622 D 364106 CDS YP_542613.1 91212627 3993796 3564395..3565828 1 NC_007946.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3565828 rpoN 3993796 rpoN Escherichia coli UTI89 RNA polymerase factor sigma-54 YP_542613.1 3564395 D 364106 CDS YP_542614.1 91212628 3993797 3565851..3566138 1 NC_007946.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3566138 yhbH 3993797 yhbH Escherichia coli UTI89 sigma(54) modulation protein YP_542614.1 3565851 D 364106 CDS YP_542615.1 91212629 3993798 3566232..3566747 1 NC_007946.1 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3566747 ptsN 3993798 ptsN Escherichia coli UTI89 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_542615.1 3566232 D 364106 CDS YP_542616.1 91212630 3993799 3566793..3567647 1 NC_007946.1 hypothetical protein 3567647 yhbJ 3993799 yhbJ Escherichia coli UTI89 hypothetical protein YP_542616.1 3566793 D 364106 CDS YP_542617.1 91212631 3993800 3567644..3567916 1 NC_007946.1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3567916 ptsO 3993800 ptsO Escherichia coli UTI89 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_542617.1 3567644 D 364106 CDS YP_542618.1 91212632 3993801 3568130..3568762 1 NC_007946.1 hypothetical protein 3568762 yrbL 3993801 yrbL Escherichia coli UTI89 hypothetical protein YP_542618.1 3568130 D 364106 CDS YP_542619.1 91212633 3993802 complement(3568759..3569487) 1 NC_007946.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3569487 mtgA 3993802 mtgA Escherichia coli UTI89 monofunctional biosynthetic peptidoglycan transglycosylase YP_542619.1 3568759 R 364106 CDS YP_542620.1 91212634 3993803 complement(3569484..3570137) 1 NC_007946.1 isoprenoid biosynthesis protein with amidotransferase-like domain 3570137 yhbL 3993803 yhbL Escherichia coli UTI89 isoprenoid biosynthesis protein with amidotransferase-like domain YP_542620.1 3569484 R 364106 CDS YP_542621.1 91212635 3993804 complement(3570367..3572703) 1 NC_007946.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3572703 arcB 3993804 arcB Escherichia coli UTI89 aerobic respiration control sensor protein ArcB YP_542621.1 3570367 R 364106 CDS YP_542622.1 91212636 3993805 complement(3572799..3573665) 1 NC_007946.1 hypothetical protein 3573665 yhcC 3993805 yhcC Escherichia coli UTI89 hypothetical protein YP_542622.1 3572799 R 364106 CDS YP_542623.1 91212637 3993806 complement(3573993..3574130) 1 NC_007946.1 hypothetical protein 3574130 3993806 UTI89_C3648 Escherichia coli UTI89 hypothetical protein YP_542623.1 3573993 R 364106 CDS YP_542624.2 162138364 3993807 3574310..3578863 1 NC_007946.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3578863 gltB 3993807 gltB Escherichia coli UTI89 glutamate synthase subunit alpha YP_542624.2 3574310 D 364106 CDS YP_542625.1 91212639 3993808 3578876..3580294 1 NC_007946.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3580294 gltD 3993808 gltD Escherichia coli UTI89 glutamate synthase subunit beta YP_542625.1 3578876 D 364106 CDS YP_542626.1 91212640 3993809 complement(3580362..3580826) 1 NC_007946.1 hypothetical protein 3580826 yhcH 3993809 yhcH Escherichia coli UTI89 hypothetical protein YP_542626.1 3580362 R 364106 CDS YP_542627.1 91212641 3993810 complement(3580823..3581731) 1 NC_007946.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3581731 3993810 UTI89_C3652 Escherichia coli UTI89 N-acetylmannosamine kinase YP_542627.1 3580823 R 364106 CDS YP_542628.1 91212642 3993811 complement(3581695..3582426) 1 NC_007946.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3582426 yhcJ 3993811 yhcJ Escherichia coli UTI89 N-acetylmannosamine-6-phosphate 2-epimerase YP_542628.1 3581695 R 364106 CDS YP_542629.1 91212643 3991279 complement(3582432..3583952) 1 NC_007946.1 sialic acid transporter 3583952 nanT 3991279 nanT Escherichia coli UTI89 sialic acid transporter YP_542629.1 3582432 R 364106 CDS YP_542630.1 91212644 3991280 complement(3584031..3584924) 1 NC_007946.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3584924 nanA 3991280 nanA Escherichia coli UTI89 N-acetylneuraminate lyase YP_542630.1 3584031 R 364106 CDS YP_542631.1 91212645 3991281 complement(3585046..3585837) 1 NC_007946.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3585837 nanR 3991281 nanR Escherichia coli UTI89 transcriptional regulator NanR YP_542631.1 3585046 R 364106 CDS YP_542632.1 91212646 3991282 complement(3585945..3586442) 1 NC_007946.1 ClpXP protease specificity-enhancing factor 3586442 sspB 3991282 sspB Escherichia coli UTI89 ClpXP protease specificity-enhancing factor YP_542632.1 3585945 R 364106 CDS YP_542633.1 91212647 3991283 complement(3586448..3587086) 1 NC_007946.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3587086 sspA 3991283 sspA Escherichia coli UTI89 stringent starvation protein A YP_542633.1 3586448 R 364106 CDS YP_542634.1 91212648 3991284 3587028..3587237 1 NC_007946.1 hypothetical protein 3587237 3991284 UTI89_C3659 Escherichia coli UTI89 hypothetical protein YP_542634.1 3587028 D 364106 CDS YP_542635.1 91212649 3991285 complement(3587481..3587873) 1 NC_007946.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3587873 rpsI 3991285 rpsI Escherichia coli UTI89 30S ribosomal protein S9 YP_542635.1 3587481 R 364106 CDS YP_542636.2 162138363 3991286 complement(3587889..3588317) 1 NC_007946.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3588317 rplM 3991286 rplM Escherichia coli UTI89 50S ribosomal protein L13 YP_542636.2 3587889 R 364106 CDS YP_542637.1 91212651 3991287 complement(3588537..3589664) 1 NC_007946.1 hypothetical protein 3589664 yhcM 3991287 yhcM Escherichia coli UTI89 hypothetical protein YP_542637.1 3588537 R 364106 CDS YP_542638.1 91212652 3991288 3589858..3590256 1 NC_007946.1 cytochrome d ubiquinol oxidase subunit III 3590256 yhcB 3991288 yhcB Escherichia coli UTI89 cytochrome d ubiquinol oxidase subunit III YP_542638.1 3589858 D 364106 CDS YP_542639.1 91212653 3991289 3589904..3590317 1 NC_007946.1 hypothetical protein 3590317 3991289 UTI89_C3664 Escherichia coli UTI89 hypothetical protein YP_542639.1 3589904 D 364106 CDS YP_542640.1 91212654 3991290 3590368..3591777 1 NC_007946.1 synonym: b3234, hhoA, EG12612; serine endoprotease 3591777 degQ 3991290 degQ Escherichia coli UTI89 serine endoprotease YP_542640.1 3590368 D 364106 CDS YP_542641.1 91212655 3991291 3591867..3592934 1 NC_007946.1 synonym: b3235, hhoB, htrH; serine endoprotease 3592934 degS 3991291 degS Escherichia coli UTI89 serine endoprotease YP_542641.1 3591867 D 364106 CDS YP_542642.1 91212656 3991292 complement(3592997..3594001) 1 NC_007946.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3594001 mdh 3991292 mdh Escherichia coli UTI89 malate dehydrogenase YP_542642.1 3592997 R 364106 CDS YP_542643.1 91212657 3991293 3594370..3594840 1 NC_007946.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3594840 argR 3991293 argR Escherichia coli UTI89 arginine repressor ArgR YP_542643.1 3594370 D 364106 CDS YP_542644.1 91212658 3991294 3595153..3595467 1 NC_007946.1 hypothetical protein 3595467 yhcN 3991294 yhcN Escherichia coli UTI89 hypothetical protein YP_542644.1 3595153 D 364106 CDS YP_542645.1 91212659 3991295 complement(3595522..3595794) 1 NC_007946.1 hypothetical protein 3595794 yhcO 3991295 yhcO Escherichia coli UTI89 hypothetical protein YP_542645.1 3595522 R 364106 CDS YP_542646.1 91212660 3991296 complement(3595886..3597853) 1 NC_007946.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3597853 3991296 UTI89_C3671 Escherichia coli UTI89 p-hydroxybenzoic acid efflux subunit AaeB YP_542646.1 3595886 R 364106 CDS YP_542647.1 91212661 3991297 complement(3597859..3598791) 1 NC_007946.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3598791 yhcQ 3991297 yhcQ Escherichia coli UTI89 p-hydroxybenzoic acid efflux subunit AaeA YP_542647.1 3597859 R 364106 CDS YP_542648.2 162138362 3991298 complement(3598799..3599002) 1 NC_007946.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3599002 yhcR 3991298 yhcR Escherichia coli UTI89 hypothetical protein YP_542648.2 3598799 R 364106 CDS YP_542649.1 91212663 3990230 3599185..3600114 1 NC_007946.1 DNA-binding transcriptional regulator 3600114 yhcS 3990230 yhcS Escherichia coli UTI89 DNA-binding transcriptional regulator YP_542649.1 3599185 D 364106 CDS YP_542650.1 91212664 3990231 complement(3600242..3601687) 1 NC_007946.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3601687 tldD 3990231 tldD Escherichia coli UTI89 protease TldD YP_542650.1 3600242 R 364106 CDS YP_542651.1 91212665 3990232 complement(3601843..3605643) 1 NC_007946.1 hypothetical protein 3605643 yhdP 3990232 yhdP Escherichia coli UTI89 hypothetical protein YP_542651.1 3601843 R 364106 CDS YP_542652.2 162138361 3990233 complement(3605711..3607180) 1 NC_007946.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3607180 rng 3990233 rng Escherichia coli UTI89 ribonuclease G YP_542652.2 3605711 R 364106 CDS YP_542653.1 91212667 3990234 complement(3607170..3607763) 1 NC_007946.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3607763 yhdE 3990234 yhdE Escherichia coli UTI89 Maf-like protein YP_542653.1 3607170 R 364106 CDS YP_542654.1 91212668 3990235 complement(3607772..3608260) 1 NC_007946.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3608260 mreD 3990235 mreD Escherichia coli UTI89 rod shape-determining protein MreD YP_542654.1 3607772 R 364106 CDS YP_542655.1 91212669 3990236 complement(3608260..3609363) 1 NC_007946.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3609363 mreC 3990236 mreC Escherichia coli UTI89 rod shape-determining protein MreC YP_542655.1 3608260 R 364106 CDS YP_542656.1 91212670 3990237 complement(3609429..3610547) 1 NC_007946.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3610547 mreB 3990237 mreB Escherichia coli UTI89 rod shape-determining protein MreB YP_542656.1 3609429 R 364106 CDS YP_542657.1 91212671 3990238 3610580..3610768 1 NC_007946.1 hypothetical protein 3610768 3990238 UTI89_C3682 Escherichia coli UTI89 hypothetical protein YP_542657.1 3610580 D 364106 CDS YP_542658.1 91212672 3990239 complement(3610777..3612717) 1 NC_007946.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3612717 yhdA 3990239 yhdA Escherichia coli UTI89 regulatory protein CsrD YP_542658.1 3610777 R 364106 CDS YP_542659.1 91212673 3990240 3612869..3613843 1 NC_007946.1 protein YhdH 3613843 yhdH 3990240 yhdH Escherichia coli UTI89 protein YhdH YP_542659.1 3612869 D 364106 CDS YP_542660.1 91212674 3990241 3613880..3614044 1 NC_007946.1 hypothetical protein 3614044 3990241 UTI89_C3685 Escherichia coli UTI89 hypothetical protein YP_542660.1 3613880 D 364106 CDS YP_542661.1 91212675 3990242 complement(3613901..3614002) 1 NC_007946.1 hypothetical protein 3614002 3990242 UTI89_C3686 Escherichia coli UTI89 hypothetical protein YP_542661.1 3613901 R 364106 CDS YP_542662.1 91212676 3990243 3614660..3614848 1 NC_007946.1 orf 5' of BCCP; hypothetical protein 3614848 3990243 UTI89_C3687 Escherichia coli UTI89 hypothetical protein YP_542662.1 3614660 D 364106 CDS YP_542663.1 91212677 3990244 3614821..3615291 1 NC_007946.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3615291 accB 3990244 accB Escherichia coli UTI89 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_542663.1 3614821 D 364106 CDS YP_542664.2 162138360 3990245 3615302..3616651 1 NC_007946.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3616651 accC 3990245 accC Escherichia coli UTI89 acetyl-CoA carboxylase biotin carboxylase subunit YP_542664.2 3615302 D 364106 CDS YP_542665.1 91212679 3990246 complement(3616743..3617789) 1 NC_007946.1 hypothetical protein 3617789 3990246 UTI89_C3690 Escherichia coli UTI89 hypothetical protein YP_542665.1 3616743 R 364106 CDS YP_542666.1 91212680 3990247 complement(3617786..3618748) 1 NC_007946.1 hypothetical protein 3618748 3990247 UTI89_C3691 Escherichia coli UTI89 hypothetical protein YP_542666.1 3617786 R 364106 CDS YP_542667.1 91212681 3990248 complement(3618770..3619759) 1 NC_007946.1 synonym: b3750, rbsA, rbsP, rbsT; ribose transport system permease RbsC 3619759 rbsC 3990248 rbsC Escherichia coli UTI89 ribose transport system permease RbsC YP_542667.1 3618770 R 364106 CDS YP_542668.1 91212682 3992776 complement(3619760..3621289) 1 NC_007946.1 synonym: rbsT, rbsP, b3749, prlB; ribose transport ATP-binding protein RbsA 3621289 3992776 UTI89_C3693 Escherichia coli UTI89 ribose transport ATP-binding protein RbsA YP_542668.1 3619760 R 364106 CDS YP_542669.1 91212683 3992777 complement(3621320..3622216) 1 NC_007946.1 ribose ABC transporter 3622216 3992777 UTI89_C3694 Escherichia coli UTI89 ribose ABC transporter YP_542669.1 3621320 R 364106 CDS YP_542670.1 91212684 3992778 complement(3622246..3623100) 1 NC_007946.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3623100 gatY 3992778 gatY Escherichia coli UTI89 tagatose-bisphosphate aldolase YP_542670.1 3622246 R 364106 CDS YP_542671.1 91212685 3992779 3623075..3623203 1 NC_007946.1 hypothetical protein 3623203 3992779 UTI89_C3696 Escherichia coli UTI89 hypothetical protein YP_542671.1 3623075 D 364106 CDS YP_542672.1 91212686 3992780 3623441..3624271 1 NC_007946.1 hypothetical protein 3624271 3992780 UTI89_C3697 Escherichia coli UTI89 hypothetical protein YP_542672.1 3623441 D 364106 CDS YP_542673.1 91212687 3992781 3624228..3625238 1 NC_007946.1 hypothetical protein 3625238 3992781 UTI89_C3698 Escherichia coli UTI89 hypothetical protein YP_542673.1 3624228 D 364106 CDS YP_542674.1 91212688 3992782 3625313..3625573 1 NC_007946.1 hypothetical protein 3625573 yhdT 3992782 yhdT Escherichia coli UTI89 hypothetical protein YP_542674.1 3625313 D 364106 CDS YP_542675.1 91212689 3992783 3625557..3627014 1 NC_007946.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3627014 panF 3992783 panF Escherichia coli UTI89 sodium/panthothenate symporter YP_542675.1 3625557 D 364106 CDS YP_542676.1 91212690 3992784 3627026..3627907 1 NC_007946.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3627907 prmA 3992784 prmA Escherichia coli UTI89 ribosomal protein L11 methyltransferase YP_542676.1 3627026 D 364106 CDS YP_542677.1 91212691 3992785 3628236..3629201 1 NC_007946.1 tRNA-dihydrouridine synthase B 3629201 yhdG 3992785 yhdG Escherichia coli UTI89 tRNA-dihydrouridine synthase B YP_542677.1 3628236 D 364106 CDS YP_542678.1 91212692 3992786 3629227..3629523 1 NC_007946.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; Fis family transcriptional regulator 3629523 fis 3992786 fis Escherichia coli UTI89 Fis family transcriptional regulator YP_542678.1 3629227 D 364106 CDS YP_542679.2 162138359 3992787 3629611..3630495 1 NC_007946.1 methyltransferase 3630495 yhdJ 3992787 yhdJ Escherichia coli UTI89 methyltransferase YP_542679.2 3629611 D 364106 CDS YP_542680.1 91212694 3992788 3630552..3630758 1 NC_007946.1 hypothetical protein 3630758 yhdU 3992788 yhdU Escherichia coli UTI89 hypothetical protein YP_542680.1 3630552 D 364106 CDS YP_542681.1 91212695 3992789 complement(3630761..3631423) 1 NC_007946.1 DNA-binding transcriptional regulator EnvR 3631423 envR 3992789 envR Escherichia coli UTI89 DNA-binding transcriptional regulator EnvR YP_542681.1 3630761 R 364106 CDS YP_542682.1 91212696 3992790 3631822..3632979 1 NC_007946.1 acriflavine resistance protein E 3632979 acrE 3992790 acrE Escherichia coli UTI89 acriflavine resistance protein E YP_542682.1 3631822 D 364106 CDS YP_542683.1 91212697 3992791 3632991..3636095 1 NC_007946.1 acriflavine resistance protein F 3636095 acrF 3992791 acrF Escherichia coli UTI89 acriflavine resistance protein F YP_542683.1 3632991 D 364106 CDS YP_542684.1 91212698 3992792 3636348..3636569 1 NC_007946.1 hypothetical protein 3636569 yhdV 3992792 yhdV Escherichia coli UTI89 hypothetical protein YP_542684.1 3636348 D 364106 CDS YP_542685.1 91212699 3992793 3637000..3638025 1 NC_007946.1 periplasmic amino-acid ABC transporter binding protein 3638025 yhdW 3992793 yhdW Escherichia coli UTI89 periplasmic amino-acid ABC transporter binding protein YP_542685.1 3637000 D 364106 CDS YP_542686.1 91212700 3992794 3638075..3639274 1 NC_007946.1 amino acid ABC transporter permease 3639274 yhdX 3992794 yhdX Escherichia coli UTI89 amino acid ABC transporter permease YP_542686.1 3638075 D 364106 CDS YP_542687.1 91212701 3992795 3639281..3640387 1 NC_007946.1 transport system permease 3640387 yhdY 3992795 yhdY Escherichia coli UTI89 transport system permease YP_542687.1 3639281 D 364106 CDS YP_542688.1 91212702 3991338 3640395..3641153 1 NC_007946.1 amino acid ABC transporter ATP-binding protein 3641153 yhdZ 3991338 yhdZ Escherichia coli UTI89 amino acid ABC transporter ATP-binding protein YP_542688.1 3640395 D 364106 CDS YP_542692.1 91212706 3991349 3646821..3647591 1 NC_007946.1 protein YrdA 3647591 yrdA 3991349 yrdA Escherichia coli UTI89 protein YrdA YP_542692.1 3646821 D 364106 CDS YP_542693.1 91212707 3990037 complement(3647567..3647824) 1 NC_007946.1 hypothetical protein 3647824 yrdB 3990037 yrdB Escherichia coli UTI89 hypothetical protein YP_542693.1 3647567 R 364106 CDS YP_542694.1 91212708 3990038 complement(3647821..3648639) 1 NC_007946.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3648639 aroE 3990038 aroE Escherichia coli UTI89 shikimate 5-dehydrogenase YP_542694.1 3647821 R 364106 CDS YP_542695.1 91212709 3990039 complement(3648644..3649261) 1 NC_007946.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 3649261 yrdC 3990039 yrdC Escherichia coli UTI89 ribosome maturation factor YP_542695.1 3648644 R 364106 CDS YP_542696.1 91212710 3990040 complement(3649221..3649763) 1 NC_007946.1 hypothetical protein 3649763 yrdD 3990040 yrdD Escherichia coli UTI89 hypothetical protein YP_542696.1 3649221 R 364106 CDS YP_542697.1 91212711 3990041 complement(3649792..3650265) 1 NC_007946.1 hypothetical protein 3650265 smg 3990041 smg Escherichia coli UTI89 hypothetical protein YP_542697.1 3649792 R 364106 CDS YP_542698.1 91212712 3990042 complement(3650237..3651361) 1 NC_007946.1 DNA protecting protein DprA 3651361 smf 3990042 smf Escherichia coli UTI89 DNA protecting protein DprA YP_542698.1 3650237 R 364106 CDS YP_542699.1 91212713 3990043 3651491..3652000 1 NC_007946.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3652000 def 3990043 def Escherichia coli UTI89 peptide deformylase YP_542699.1 3651491 D 364106 CDS YP_542700.1 91212714 3990044 3652015..3652962 1 NC_007946.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3652962 fmt 3990044 fmt Escherichia coli UTI89 methionyl-tRNA formyltransferase YP_542700.1 3652015 D 364106 CDS YP_542701.1 91212715 3990045 3653014..3654303 1 NC_007946.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3654303 sun 3990045 sun Escherichia coli UTI89 16S rRNA methyltransferase GidB YP_542701.1 3653014 D 364106 CDS YP_542702.1 91212716 3990046 3654325..3655701 1 NC_007946.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 3655701 trkA 3990046 trkA Escherichia coli UTI89 potassium transporter peripheral membrane component YP_542702.1 3654325 D 364106 CDS YP_542703.1 91212717 3990047 3655831..3656244 1 NC_007946.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3656244 mscL 3990047 mscL Escherichia coli UTI89 large-conductance mechanosensitive channel YP_542703.1 3655831 D 364106 CDS YP_542704.1 91212718 3990048 complement(3656241..3656459) 1 NC_007946.1 regulator 3656459 yhdL 3990048 yhdL Escherichia coli UTI89 regulator YP_542704.1 3656241 R 364106 CDS YP_542705.1 91212719 3990049 complement(3656515..3656940) 1 NC_007946.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3656940 zntR 3990049 zntR Escherichia coli UTI89 zinc-responsive transcriptional regulator YP_542705.1 3656515 R 364106 CDS YP_542706.1 91212720 3990050 complement(3656951..3657319) 1 NC_007946.1 hypothetical protein 3657319 yhdN 3990050 yhdN Escherichia coli UTI89 hypothetical protein YP_542706.1 3656951 R 364106 CDS YP_542707.1 91212721 3990051 complement(3657426..3657809) 1 NC_007946.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3657809 rplQ 3990051 rplQ Escherichia coli UTI89 50S ribosomal protein L17 YP_542707.1 3657426 R 364106 CDS YP_542708.1 91212722 3990052 complement(3657850..3658839) 1 NC_007946.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3658839 rpoA 3990052 rpoA Escherichia coli UTI89 DNA-directed RNA polymerase subunit alpha YP_542708.1 3657850 R 364106 CDS YP_542709.1 91212723 3990053 complement(3658865..3659485) 1 NC_007946.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3659485 rpsD 3990053 rpsD Escherichia coli UTI89 30S ribosomal protein S4 YP_542709.1 3658865 R 364106 CDS YP_542710.1 91212724 3990054 complement(3659519..3659908) 1 NC_007946.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3659908 rpsK 3990054 rpsK Escherichia coli UTI89 30S ribosomal protein S11 YP_542710.1 3659519 R 364106 CDS YP_542712.1 91212726 3990056 complement(3659925..3660281) 1 NC_007946.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3660281 rpsM 3990056 rpsM Escherichia coli UTI89 30S ribosomal protein S13 YP_542712.1 3659925 R 364106 CDS YP_542713.1 91212727 3991222 complement(3660428..3660544) 1 NC_007946.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3660544 rpmJ 3991222 rpmJ Escherichia coli UTI89 50S ribosomal protein L36 YP_542713.1 3660428 R 364106 CDS YP_542714.1 91212728 3991223 complement(3660576..3661907) 1 NC_007946.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3661907 secY 3991223 secY Escherichia coli UTI89 preprotein translocase subunit SecY YP_542714.1 3660576 R 364106 CDS YP_542715.1 91212729 3991224 complement(3661915..3662349) 1 NC_007946.1 late assembly protein; 50S ribosomal protein L15 3662349 rplO 3991224 rplO Escherichia coli UTI89 50S ribosomal protein L15 YP_542715.1 3661915 R 364106 CDS YP_542716.1 91212730 3991225 complement(3662353..3662532) 1 NC_007946.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3662532 rpmD 3991225 rpmD Escherichia coli UTI89 50S ribosomal protein L30 YP_542716.1 3662353 R 364106 CDS YP_542717.1 91212731 3991226 3662506..3663057 1 NC_007946.1 hypothetical protein 3663057 3991226 UTI89_C3749 Escherichia coli UTI89 hypothetical protein YP_542717.1 3662506 D 364106 CDS YP_542718.1 91212732 3991227 complement(3662536..3663039) 1 NC_007946.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3663039 rpsE 3991227 rpsE Escherichia coli UTI89 30S ribosomal protein S5 YP_542718.1 3662536 R 364106 CDS YP_542719.1 91212733 3991228 complement(3663054..3663407) 1 NC_007946.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3663407 rplR 3991228 rplR Escherichia coli UTI89 50S ribosomal protein L18 YP_542719.1 3663054 R 364106 CDS YP_542720.1 91212734 3991229 3663108..3663731 1 NC_007946.1 hypothetical protein 3663731 3991229 UTI89_C3752 Escherichia coli UTI89 hypothetical protein YP_542720.1 3663108 D 364106 CDS YP_542721.1 91212735 3991230 complement(3663417..3663950) 1 NC_007946.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3663950 rplF 3991230 rplF Escherichia coli UTI89 50S ribosomal protein L6 YP_542721.1 3663417 R 364106 CDS YP_542722.1 91212736 3991231 3663816..3664373 1 NC_007946.1 hypothetical protein 3664373 3991231 UTI89_C3754 Escherichia coli UTI89 hypothetical protein YP_542722.1 3663816 D 364106 CDS YP_542723.1 91212737 3991232 complement(3663963..3664355) 1 NC_007946.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3664355 rpsH 3991232 rpsH Escherichia coli UTI89 30S ribosomal protein S8 YP_542723.1 3663963 R 364106 CDS YP_542724.1 91212738 3991233 complement(3664389..3664694) 1 NC_007946.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3664694 rpsN 3991233 rpsN Escherichia coli UTI89 30S ribosomal protein S14 YP_542724.1 3664389 R 364106 CDS YP_542725.1 91212739 3991234 complement(3664709..3665248) 1 NC_007946.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3665248 rplE 3991234 rplE Escherichia coli UTI89 50S ribosomal protein L5 YP_542725.1 3664709 R 364106 CDS YP_542726.1 91212740 3991235 complement(3665263..3665577) 1 NC_007946.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3665577 rplX 3991235 rplX Escherichia coli UTI89 50S ribosomal protein L24 YP_542726.1 3665263 R 364106 CDS YP_542727.1 91212741 3991236 3665459..3666013 1 NC_007946.1 hypothetical protein 3666013 3991236 UTI89_C3759 Escherichia coli UTI89 hypothetical protein YP_542727.1 3665459 D 364106 CDS YP_542728.1 91212742 3991237 complement(3665588..3665959) 1 NC_007946.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3665959 rplN 3991237 rplN Escherichia coli UTI89 50S ribosomal protein L14 YP_542728.1 3665588 R 364106 CDS YP_542729.1 91212743 3991238 complement(3666124..3666378) 1 NC_007946.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3666378 rpsQ 3991238 rpsQ Escherichia coli UTI89 30S ribosomal protein S17 YP_542729.1 3666124 R 364106 CDS YP_542730.1 91212744 3991239 complement(3666378..3666569) 1 NC_007946.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3666569 rpmC 3991239 rpmC Escherichia coli UTI89 50S ribosomal protein L29 YP_542730.1 3666378 R 364106 CDS YP_542732.1 91212746 3994686 complement(3666569..3666979) 1 NC_007946.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3666979 rplP 3994686 rplP Escherichia coli UTI89 50S ribosomal protein L16 YP_542732.1 3666569 R 364106 CDS YP_542733.1 91212747 3994687 complement(3666992..3667693) 1 NC_007946.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3667693 rpsC 3994687 rpsC Escherichia coli UTI89 30S ribosomal protein S3 YP_542733.1 3666992 R 364106 CDS YP_542735.1 91212749 3994689 complement(3667711..3668043) 1 NC_007946.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3668043 rplV 3994689 rplV Escherichia coli UTI89 50S ribosomal protein L22 YP_542735.1 3667711 R 364106 CDS YP_542736.1 91212750 3994690 complement(3668058..3668336) 1 NC_007946.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3668336 rpsS 3994690 rpsS Escherichia coli UTI89 30S ribosomal protein S19 YP_542736.1 3668058 R 364106 CDS YP_542737.1 91212751 3994691 3668320..3669246 1 NC_007946.1 hypothetical protein 3669246 3994691 UTI89_C3769 Escherichia coli UTI89 hypothetical protein YP_542737.1 3668320 D 364106 CDS YP_542738.1 91212752 3994692 complement(3668353..3669174) 1 NC_007946.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3669174 rplB 3994692 rplB Escherichia coli UTI89 50S ribosomal protein L2 YP_542738.1 3668353 R 364106 CDS YP_542739.1 91212753 3994693 complement(3669192..3669494) 1 NC_007946.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3669494 rplW 3994693 rplW Escherichia coli UTI89 50S ribosomal protein L23 YP_542739.1 3669192 R 364106 CDS YP_542741.1 91212755 3994695 complement(3669491..3670096) 1 NC_007946.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3670096 rplD 3994695 rplD Escherichia coli UTI89 50S ribosomal protein L4 YP_542741.1 3669491 R 364106 CDS YP_542742.1 91212756 3994696 3670026..3670727 1 NC_007946.1 hypothetical protein 3670727 3994696 UTI89_C3774 Escherichia coli UTI89 hypothetical protein YP_542742.1 3670026 D 364106 CDS YP_542743.1 91212757 3994697 complement(3670107..3670736) 1 NC_007946.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3670736 rplC 3994697 rplC Escherichia coli UTI89 50S ribosomal protein L3 YP_542743.1 3670107 R 364106 CDS YP_542744.1 91212758 3994698 complement(3670769..3671080) 1 NC_007946.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3671080 rpsJ 3994698 rpsJ Escherichia coli UTI89 30S ribosomal protein S10 YP_542744.1 3670769 R 364106 CDS YP_542745.1 91212759 3994699 complement(3671318..3671737) 1 NC_007946.1 calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 3671737 pinO 3994699 pinO Escherichia coli UTI89 chromosome replication protein PioO YP_542745.1 3671318 R 364106 CDS YP_542746.1 91212760 3994700 complement(3671739..3673208) 1 NC_007946.1 synonym: b3323, yheD, EG12888; general secretion pathway protein A 3673208 yheD 3994700 yheD Escherichia coli UTI89 general secretion pathway protein A YP_542746.1 3671739 R 364106 CDS YP_542747.1 91212761 3994701 3673388..3674203 1 NC_007946.1 synonym: b3324, yheE, EG12889; general secretion pathway protein C 3674203 yheE 3994701 yheE Escherichia coli UTI89 general secretion pathway protein C YP_542747.1 3673388 D 364106 CDS YP_542748.1 91212762 3994702 3674175..3676139 1 NC_007946.1 synonym: b3325, yheF, EG12890; general secretion pathway protein D 3676139 yheF 3994702 yheF Escherichia coli UTI89 general secretion pathway protein D YP_542748.1 3674175 D 364106 CDS YP_542749.1 91212763 3994703 3676149..3677630 1 NC_007946.1 synonym: b3326, yheG, EG12891; general secretion pathway protein E 3677630 yheG 3994703 yheG Escherichia coli UTI89 general secretion pathway protein E YP_542749.1 3676149 D 364106 CDS YP_542750.1 91212764 3994704 3677627..3678823 1 NC_007946.1 synonym: b3327, hofF, hopF, EG12885; general secretion pathway protein F 3678823 hofF 3994704 hofF Escherichia coli UTI89 general secretion pathway protein F YP_542750.1 3677627 D 364106 CDS YP_542751.1 91212765 3994705 3678833..3679270 1 NC_007946.1 synonym: b3328, hofG, hopG, hopg, EG12886; general secretion pathway protein G 3679270 hofG 3994705 hofG Escherichia coli UTI89 general secretion pathway protein G YP_542751.1 3678833 D 364106 CDS YP_542752.1 91212766 3993447 3679278..3679787 1 NC_007946.1 synonym: b3329, hofH, hopH, EG12887; general secretion pathway protein H 3679787 hofH 3993447 hofH Escherichia coli UTI89 general secretion pathway protein H YP_542752.1 3679278 D 364106 CDS YP_542753.1 91212767 3993448 3679745..3680179 1 NC_007946.1 synonym: b3330, yheH, yheh, EG12892; general secretion pathway protein I 3680179 yheH 3993448 yheH Escherichia coli UTI89 general secretion pathway protein I YP_542753.1 3679745 D 364106 CDS YP_542754.1 91212768 3993449 3680172..3680759 1 NC_007946.1 synonym: b3331, yheI, yhei, EG12893; general secretion pathway protein J 3680759 yheI 3993449 yheI Escherichia coli UTI89 general secretion pathway protein J YP_542754.1 3680172 D 364106 CDS YP_542755.1 91212769 3993450 3680752..3681735 1 NC_007946.1 synonym: b3332, yheJ, yhej, EG12894; general secretion pathway protein K 3681735 yheJ 3993450 yheJ Escherichia coli UTI89 general secretion pathway protein K YP_542755.1 3680752 D 364106 CDS YP_542756.1 91212770 3993451 3681747..3682913 1 NC_007946.1 synonym: b3333, yheK, yheL, yhek, EG12895; general secretion pathway protein L 3682913 yheK 3993451 yheK Escherichia coli UTI89 general secretion pathway protein L YP_542756.1 3681747 D 364106 CDS YP_542757.1 91212771 3993452 3682886..3683371 1 NC_007946.1 synonym: b3334, hopZ, pshM; general secretion pathway protein M 3683371 pshM 3993452 pshM Escherichia coli UTI89 general secretion pathway protein M YP_542757.1 3682886 D 364106 CDS YP_542758.1 91212772 3993453 3683371..3684048 1 NC_007946.1 synonym: b3335, hofD, hopD, hopO, yheC; type 4 prepilin-like proteins leader peptide processing enzyme 3684048 hofD 3993453 hofD Escherichia coli UTI89 type 4 prepilin-like proteins leader peptide processing enzyme YP_542758.1 3683371 D 364106 CDS YP_542759.1 91212773 3993454 complement(3684077..3684553) 1 NC_007946.1 iron storage protein; bacterioferritin 3684553 bfr 3993454 bfr Escherichia coli UTI89 bacterioferritin YP_542759.1 3684077 R 364106 CDS YP_542760.1 91212774 3993455 complement(3684625..3684819) 1 NC_007946.1 synonym: b3337, yheA, gen-64; bacterioferritin-associated ferredoxin 3684819 bfd 3993455 bfd Escherichia coli UTI89 bacterioferritin-associated ferredoxin YP_542760.1 3684625 R 364106 CDS YP_542761.1 91212775 3993456 complement(3684988..3687690) 1 NC_007946.1 bifunctional chitinase/lysozyme 3687690 yheB 3993456 yheB Escherichia coli UTI89 bifunctional chitinase/lysozyme YP_542761.1 3684988 R 364106 CDS YP_542762.1 91212776 3993457 complement(3687775..3687933) 1 NC_007946.1 hypothetical protein 3687933 3993457 UTI89_C3794 Escherichia coli UTI89 hypothetical protein YP_542762.1 3687775 R 364106 CDS YP_542763.1 91212777 3993458 complement(3687982..3689166) 1 NC_007946.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3689166 tufB 3993458 tufB Escherichia coli UTI89 elongation factor Tu YP_542763.1 3687982 R 364106 CDS YP_542764.1 91212778 3990846 3689742..3689897 1 NC_007946.1 hypothetical protein 3689897 3990846 UTI89_C3800 Escherichia coli UTI89 hypothetical protein YP_542764.1 3689742 D 364106 CDS YP_542765.1 91212779 3990847 3689866..3690027 1 NC_007946.1 hypothetical protein 3690027 3990847 UTI89_C3801 Escherichia coli UTI89 hypothetical protein YP_542765.1 3689866 D 364106 CDS YP_542766.1 91212780 3990848 3690063..3691034 1 NC_007946.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3691034 coaA 3990848 coaA Escherichia coli UTI89 pantothenate kinase YP_542766.1 3690063 D 364106 CDS YP_542767.1 91212781 3990849 complement(3691063..3692028) 1 NC_007946.1 BirA bifunctional protein; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 3692028 birA 3990849 birA Escherichia coli UTI89 biotin--protein ligase YP_542767.1 3691063 R 364106 CDS YP_542768.1 91212782 3990850 complement(3692025..3693053) 1 NC_007946.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3693053 murB 3990850 murB Escherichia coli UTI89 UDP-N-acetylenolpyruvoylglucosamine reductase YP_542768.1 3692025 R 364106 CDS YP_542773.1 91212787 3990859 complement(3698578..3698700) 1 NC_007946.1 hypothetical protein 3698700 3990859 UTI89_C3813 Escherichia coli UTI89 hypothetical protein YP_542773.1 3698578 R 364106 CDS YP_542774.1 91212788 3990860 3698818..3700407 1 NC_007946.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3700407 purH 3990860 purH Escherichia coli UTI89 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_542774.1 3698818 D 364106 CDS YP_542775.1 91212789 3990788 3700419..3701708 1 NC_007946.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3701708 purD 3990788 purD Escherichia coli UTI89 phosphoribosylamine--glycine ligase YP_542775.1 3700419 D 364106 CDS YP_542776.1 91212790 3990789 complement(3703026..3704402) 1 NC_007946.1 synonym: b4003, hydH; sensor protein ZraS 3704402 zraS 3990789 zraS Escherichia coli UTI89 sensor protein ZraS YP_542776.1 3703026 R 364106 CDS YP_542777.2 162138358 3990790 3704640..3705059 1 NC_007946.1 synonym: b4002, yjaI, zra; zinc resistance protein 3705059 zraP 3990790 zraP Escherichia coli UTI89 zinc resistance protein YP_542777.2 3704640 D 364106 CDS YP_542778.1 91212792 3990791 complement(3705061..3705762) 1 NC_007946.1 hypothetical protein 3705762 yjaH 3990791 yjaH Escherichia coli UTI89 hypothetical protein YP_542778.1 3705061 R 364106 CDS YP_542779.1 91212793 3990792 complement(3705769..3706041) 1 NC_007946.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 3706041 hupA 3990792 hupA Escherichia coli UTI89 transcriptional regulator HU subunit alpha YP_542779.1 3705769 R 364106 CDS YP_542780.1 91212794 3990793 complement(3706228..3706818) 1 NC_007946.1 hypothetical protein 3706818 yjaG 3990793 yjaG Escherichia coli UTI89 hypothetical protein YP_542780.1 3706228 R 364106 CDS YP_542781.1 91212795 3990794 complement(3706861..3707532) 1 NC_007946.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 3707532 nfi 3990794 nfi Escherichia coli UTI89 endonuclease V YP_542781.1 3706861 R 364106 CDS YP_542782.1 91212796 3990795 complement(3707542..3708606) 1 NC_007946.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 3708606 hemE 3990795 hemE Escherichia coli UTI89 uroporphyrinogen decarboxylase YP_542782.1 3707542 R 364106 CDS YP_542783.1 91212797 3990796 complement(3708646..3709419) 1 NC_007946.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 3709419 nudC 3990796 nudC Escherichia coli UTI89 NADH pyrophosphatase YP_542783.1 3708646 R 364106 CDS YP_542784.1 91212798 3990797 3709514..3709990 1 NC_007946.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 3709990 yjaE 3990797 yjaE Escherichia coli UTI89 anti-RNA polymerase sigma 70 factor YP_542784.1 3709514 D 364106 CDS YP_542785.1 91212799 3990798 3710211..3712118 1 NC_007946.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3712118 thiC 3990798 thiC Escherichia coli UTI89 thiamine biosynthesis protein ThiC YP_542785.1 3710211 D 364106 CDS YP_542786.1 91212800 3990799 3712115..3712753 1 NC_007946.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 3712753 thiE 3990799 thiE Escherichia coli UTI89 thiamine-phosphate pyrophosphorylase YP_542786.1 3712115 D 364106 CDS YP_542787.1 91212801 3990800 3712731..3713501 1 NC_007946.1 adenylyltransferase 3713501 thiF 3990800 thiF Escherichia coli UTI89 adenylyltransferase YP_542787.1 3712731 D 364106 CDS YP_542788.1 91212802 3990801 3713485..3713685 1 NC_007946.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 3713685 3990801 UTI89_C3828 Escherichia coli UTI89 sulfur carrier protein ThiS YP_542788.1 3713485 D 364106 CDS YP_542789.2 162138357 3990802 3713687..3714457 1 NC_007946.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 3714457 thiG 3990802 thiG Escherichia coli UTI89 thiazole synthase YP_542789.2 3713687 D 364106 CDS YP_542790.1 91212804 3990803 3714454..3715587 1 NC_007946.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 3715587 thiH 3990803 thiH Escherichia coli UTI89 thiamine biosynthesis protein ThiH YP_542790.1 3714454 D 364106 CDS YP_542791.1 91212805 3990804 complement(3715827..3720050) 1 NC_007946.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 3720050 rpoC 3990804 rpoC Escherichia coli UTI89 DNA-directed RNA polymerase subunit beta' YP_542791.1 3715827 R 364106 CDS YP_542792.1 91212806 3990805 complement(3720127..3724188) 1 NC_007946.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 3724188 rpoB 3990805 rpoB Escherichia coli UTI89 DNA-directed RNA polymerase subunit beta YP_542792.1 3720127 R 364106 CDS YP_542793.1 91212807 3990806 3724349..3724855 1 NC_007946.1 hypothetical protein 3724855 3990806 UTI89_C3833 Escherichia coli UTI89 hypothetical protein YP_542793.1 3724349 D 364106 CDS YP_542794.1 91212808 3993272 complement(3724475..3724840) 1 NC_007946.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 3724840 rplL 3993272 rplL Escherichia coli UTI89 50S ribosomal protein L7/L12 YP_542794.1 3724475 R 364106 CDS YP_542795.1 91212809 3993273 complement(3724907..3725404) 1 NC_007946.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 3725404 rplJ 3993273 rplJ Escherichia coli UTI89 50S ribosomal protein L10 YP_542795.1 3724907 R 364106 CDS YP_542796.1 91212810 3993274 complement(3725696..3726400) 1 NC_007946.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 3726400 rplA 3993274 rplA Escherichia coli UTI89 50S ribosomal protein L1 YP_542796.1 3725696 R 364106 CDS YP_542797.1 91212811 3993275 3725885..3726886 1 NC_007946.1 hypothetical protein 3726886 3993275 UTI89_C3837 Escherichia coli UTI89 hypothetical protein YP_542797.1 3725885 D 364106 CDS YP_542798.1 91212812 3993276 complement(3726404..3726832) 1 NC_007946.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 3726832 rplK 3993276 rplK Escherichia coli UTI89 50S ribosomal protein L11 YP_542798.1 3726404 R 364106 CDS YP_542799.1 91212813 3993277 complement(3726991..3727536) 1 NC_007946.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 3727536 nusG 3993277 nusG Escherichia coli UTI89 transcription antitermination protein NusG YP_542799.1 3726991 R 364106 CDS YP_542800.1 91212814 3993278 complement(3727538..3727921) 1 NC_007946.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 3727921 secE 3993278 secE Escherichia coli UTI89 preprotein translocase subunit SecE YP_542800.1 3727538 R 364106 CDS YP_542801.2 162138356 3993279 complement(3728151..3729335) 1 NC_007946.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3729335 tufA 3993279 tufA Escherichia coli UTI89 elongation factor Tu YP_542801.2 3728151 R 364106 CDS YP_542802.1 91212816 3993280 complement(3729406..3731520) 1 NC_007946.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3731520 fusA 3993280 fusA Escherichia coli UTI89 elongation factor G YP_542802.1 3729406 R 364106 CDS YP_542803.1 91212817 3993281 complement(3731617..3732087) 1 NC_007946.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3732087 rpsG 3993281 rpsG Escherichia coli UTI89 30S ribosomal protein S7 YP_542803.1 3731617 R 364106 CDS YP_542804.2 162138355 3993282 complement(3732184..3732558) 1 NC_007946.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3732558 rpsL 3993282 rpsL Escherichia coli UTI89 30S ribosomal protein S12 YP_542804.2 3732184 R 364106 CDS YP_542805.1 91212819 3993283 complement(3732684..3732971) 1 NC_007946.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3732971 yheL 3993283 yheL Escherichia coli UTI89 sulfur transfer complex subunit TusB YP_542805.1 3732684 R 364106 CDS YP_542806.1 91212820 3993284 complement(3732978..3733337) 1 NC_007946.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3733337 yheM 3993284 yheM Escherichia coli UTI89 sulfur relay protein TusC YP_542806.1 3732978 R 364106 CDS YP_542807.1 91212821 3993285 complement(3733337..3733723) 1 NC_007946.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3733723 yheN 3993285 yheN Escherichia coli UTI89 sulfur transfer complex subunit TusD YP_542807.1 3733337 R 364106 CDS YP_542808.1 91212822 3993286 complement(3733723..3734457) 1 NC_007946.1 hypothetical protein 3734457 yheO 3993286 yheO Escherichia coli UTI89 hypothetical protein YP_542808.1 3733723 R 364106 CDS YP_542809.1 91212823 3993287 complement(3734612..3735424) 1 NC_007946.1 rotamase; FKBP-type peptidylprolyl isomerase 3735424 fkpA 3993287 fkpA Escherichia coli UTI89 FKBP-type peptidylprolyl isomerase YP_542809.1 3734612 R 364106 CDS YP_542810.1 91212824 3993288 3735645..3735863 1 NC_007946.1 hypothetical protein 3735863 slyX 3993288 slyX Escherichia coli UTI89 hypothetical protein YP_542810.1 3735645 D 364106 CDS YP_542811.1 91212825 3993289 complement(3735912..3736502) 1 NC_007946.1 rotamase; FKBP-type peptidylprolyl isomerase 3736502 slyD 3993289 slyD Escherichia coli UTI89 FKBP-type peptidylprolyl isomerase YP_542811.1 3735912 R 364106 CDS YP_542812.1 91212826 3993290 complement(3736597..3736797) 1 NC_007946.1 hypothetical protein 3736797 yheV 3993290 yheV Escherichia coli UTI89 hypothetical protein YP_542812.1 3736597 R 364106 CDS YP_542813.1 91212827 3993291 complement(3736807..3738612) 1 NC_007946.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3738612 kefB 3993291 kefB Escherichia coli UTI89 glutathione-regulated potassium-efflux system protein KefB YP_542813.1 3736807 R 364106 CDS YP_542814.1 91212828 3993428 complement(3738612..3739166) 1 NC_007946.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3739166 yheR 3993428 yheR Escherichia coli UTI89 glutathione-regulated potassium-efflux system ancillary protein KefG YP_542814.1 3738612 R 364106 CDS YP_542815.1 91212829 3993429 3739294..3741207 1 NC_007946.1 ABC transporter ATP-binding protein 3741207 yheS 3993429 yheS Escherichia coli UTI89 ABC transporter ATP-binding protein YP_542815.1 3739294 D 364106 CDS YP_542816.1 91212830 3993430 3741207..3742229 1 NC_007946.1 hydrolase 3742229 yheT 3993430 yheT Escherichia coli UTI89 hydrolase YP_542816.1 3741207 D 364106 CDS YP_542817.1 91212831 3993431 3742223..3742441 1 NC_007946.1 hypothetical protein 3742441 yheU 3993431 yheU Escherichia coli UTI89 hypothetical protein YP_542817.1 3742223 D 364106 CDS YP_542818.1 91212832 3993432 3742495..3743364 1 NC_007946.1 synonym: b3355, yhfF; phosphoribulokinase 3743364 prkB 3993432 prkB Escherichia coli UTI89 phosphoribulokinase YP_542818.1 3742495 D 364106 CDS YP_542819.1 91212833 3993433 complement(3743419..3743823) 1 NC_007946.1 hypothetical protein 3743823 yhfA 3993433 yhfA Escherichia coli UTI89 hypothetical protein YP_542819.1 3743419 R 364106 CDS YP_542820.1 91212834 3993434 3744125..3744757 1 NC_007946.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3744757 crp 3993434 crp Escherichia coli UTI89 cAMP-regulatory protein YP_542820.1 3744125 D 364106 CDS YP_542821.1 91212835 3993435 3744796..3746898 1 NC_007946.1 hypothetical protein 3746898 yhfK 3993435 yhfK Escherichia coli UTI89 hypothetical protein YP_542821.1 3744796 D 364106 CDS YP_542822.1 91212836 3993436 complement(3746965..3748185) 1 NC_007946.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 3748185 argD 3993436 argD Escherichia coli UTI89 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase YP_542822.1 3746965 R 364106 CDS YP_542823.1 91212837 3993437 complement(3748271..3748834) 1 NC_007946.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3748834 pabA 3993437 pabA Escherichia coli UTI89 para-aminobenzoate synthase component II YP_542823.1 3748271 R 364106 CDS YP_542824.1 91212838 3993438 complement(3748866..3749468) 1 NC_007946.1 cell filamentation protein Fic 3749468 fic 3993438 fic Escherichia coli UTI89 cell filamentation protein Fic YP_542824.1 3748866 R 364106 CDS YP_542825.1 91212839 3993439 complement(3749458..3749625) 1 NC_007946.1 hypothetical protein 3749625 yhfG 3993439 yhfG Escherichia coli UTI89 hypothetical protein YP_542825.1 3749458 R 364106 CDS YP_542826.1 91212840 3993440 complement(3749730..3750302) 1 NC_007946.1 peptidyl-prolyl cis-trans isomerase A 3750302 ppiA 3993440 ppiA Escherichia coli UTI89 peptidyl-prolyl cis-trans isomerase A YP_542826.1 3749730 R 364106 CDS YP_542827.1 91212841 3993441 3750572..3751753 1 NC_007946.1 hypothetical protein 3751753 yhfC 3993441 yhfC Escherichia coli UTI89 hypothetical protein YP_542827.1 3750572 D 364106 CDS YP_542828.1 91212842 3993442 complement(3751886..3752062) 1 NC_007946.1 hypothetical protein 3752062 3993442 UTI89_C3868 Escherichia coli UTI89 hypothetical protein YP_542828.1 3751886 R 364106 CDS YP_542829.1 91212843 3993443 3752015..3754558 1 NC_007946.1 nitrite reductase [NAD(P)H] large subunit 3754558 nirB 3993443 nirB Escherichia coli UTI89 nitrite reductase [NAD(P)H] large subunit YP_542829.1 3752015 D 364106 CDS YP_542830.1 91212844 3993444 3754555..3754881 1 NC_007946.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3754881 nirD 3993444 nirD Escherichia coli UTI89 nitrite reductase small subunit YP_542830.1 3754555 D 364106 CDS YP_542831.1 91212845 3993445 3755007..3755813 1 NC_007946.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3755813 nirC 3993445 nirC Escherichia coli UTI89 nitrite transporter NirC YP_542831.1 3755007 D 364106 CDS YP_542832.1 91212846 3993446 3755832..3757205 1 NC_007946.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3757205 cysG 3993446 cysG Escherichia coli UTI89 siroheme synthase YP_542832.1 3755832 D 364106 CDS YP_542833.1 91212847 3993639 3757457..3757624 1 NC_007946.1 hypothetical protein 3757624 yhfL 3993639 yhfL Escherichia coli UTI89 hypothetical protein YP_542833.1 3757457 D 364106 CDS YP_542834.1 91212848 3993640 complement(3757732..3758817) 1 NC_007946.1 hypothetical protein 3758817 yhfS 3993640 yhfS Escherichia coli UTI89 hypothetical protein YP_542834.1 3757732 R 364106 CDS YP_542835.1 91212849 3993641 complement(3758829..3760133) 1 NC_007946.1 hypothetical protein 3760133 yhfT 3993641 yhfT Escherichia coli UTI89 hypothetical protein YP_542835.1 3758829 R 364106 CDS YP_542836.1 91212850 3993642 complement(3760145..3760537) 1 NC_007946.1 hypothetical protein 3760537 yhfU 3993642 yhfU Escherichia coli UTI89 hypothetical protein YP_542836.1 3760145 R 364106 CDS YP_542837.1 91212851 3993643 complement(3760509..3761387) 1 NC_007946.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase 3761387 yhfV 3993643 yhfV Escherichia coli UTI89 hydrolase YP_542837.1 3760509 R 364106 CDS YP_542838.1 91212852 3993644 complement(3761384..3762610) 1 NC_007946.1 mutase 3762610 yhfW 3993644 yhfW Escherichia coli UTI89 mutase YP_542838.1 3761384 R 364106 CDS YP_542839.1 91212853 3993645 complement(3762611..3763774) 1 NC_007946.1 hypothetical protein 3763774 yhfX 3993645 yhfX Escherichia coli UTI89 hypothetical protein YP_542839.1 3762611 R 364106 CDS YP_542840.1 91212854 3993646 complement(3763858..3764262) 1 NC_007946.1 hypothetical protein 3764262 yhfY 3993646 yhfY Escherichia coli UTI89 hypothetical protein YP_542840.1 3763858 R 364106 CDS YP_542841.1 91212855 3993647 complement(3764237..3765142) 1 NC_007946.1 hypothetical protein 3765142 yhfZ 3993647 yhfZ Escherichia coli UTI89 hypothetical protein YP_542841.1 3764237 R 364106 CDS YP_542842.1 91212856 3993648 complement(3765302..3766306) 1 NC_007946.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3766306 trpS 3993648 trpS Escherichia coli UTI89 tryptophanyl-tRNA synthetase YP_542842.1 3765302 R 364106 CDS YP_542843.1 91212857 3993649 complement(3766299..3767057) 1 NC_007946.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3767057 gph 3993649 gph Escherichia coli UTI89 phosphoglycolate phosphatase YP_542843.1 3766299 R 364106 CDS YP_542844.1 91212858 3993650 complement(3767050..3767727) 1 NC_007946.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3767727 rpe 3993650 rpe Escherichia coli UTI89 ribulose-phosphate 3-epimerase YP_542844.1 3767050 R 364106 CDS YP_542845.1 91212859 3993651 complement(3767745..3768581) 1 NC_007946.1 DNA adenine methylase 3768581 dam 3993651 dam Escherichia coli UTI89 DNA adenine methylase YP_542845.1 3767745 R 364106 CDS YP_542846.1 91212860 3993652 complement(3768688..3769974) 1 NC_007946.1 hypothetical protein 3769974 damX 3993652 damX Escherichia coli UTI89 hypothetical protein YP_542846.1 3768688 R 364106 CDS YP_542847.1 91212861 3993653 complement(3770066..3771154) 1 NC_007946.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3771154 aroB 3993653 aroB Escherichia coli UTI89 3-dehydroquinate synthase YP_542847.1 3770066 R 364106 CDS YP_542848.1 91212862 3993654 complement(3771211..3771933) 1 NC_007946.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3771933 aroK 3993654 aroK Escherichia coli UTI89 shikimate kinase I YP_542848.1 3771211 R 364106 CDS YP_542849.1 91212863 3993655 complement(3772133..3773371) 1 NC_007946.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; porin 3773371 hofQ 3993655 hofQ Escherichia coli UTI89 porin YP_542849.1 3772133 R 364106 CDS YP_542850.1 91212864 3993656 complement(3773283..3773726) 1 NC_007946.1 hypothetical protein 3773726 yrfA 3993656 yrfA Escherichia coli UTI89 hypothetical protein YP_542850.1 3773283 R 364106 CDS YP_542851.1 91212865 3993657 complement(3773677..3774117) 1 NC_007946.1 hypothetical protein 3774117 yrfB 3993657 yrfB Escherichia coli UTI89 hypothetical protein YP_542851.1 3773677 R 364106 CDS YP_542852.1 91212866 3993658 complement(3774101..3774640) 1 NC_007946.1 hypothetical protein 3774640 yrfC 3993658 yrfC Escherichia coli UTI89 hypothetical protein YP_542852.1 3774101 R 364106 CDS YP_542853.1 91212867 3991402 complement(3774640..3775446) 1 NC_007946.1 hypothetical protein 3775446 yrfD 3991402 yrfD Escherichia coli UTI89 hypothetical protein YP_542853.1 3774640 R 364106 CDS YP_542854.1 91212868 3991403 3775515..3778091 1 NC_007946.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3778091 mrcA 3991403 mrcA Escherichia coli UTI89 peptidoglycan synthetase YP_542854.1 3775515 D 364106 CDS YP_542855.1 91212869 3991404 complement(3778257..3778817) 1 NC_007946.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3778817 nudE 3991404 nudE Escherichia coli UTI89 ADP-ribose diphosphatase NudE YP_542855.1 3778257 R 364106 CDS YP_542856.1 91212870 3991405 3779137..3781272 1 NC_007946.1 IgaA-like membrane protein 3781272 yrfF 3991405 yrfF Escherichia coli UTI89 IgaA-like membrane protein YP_542856.1 3779137 D 364106 CDS YP_542857.1 91212871 3991406 3781292..3782005 1 NC_007946.1 phosphatase 3782005 yrfG 3991406 yrfG Escherichia coli UTI89 phosphatase YP_542857.1 3781292 D 364106 CDS YP_542858.1 91212872 3991407 3782016..3782417 1 NC_007946.1 synonym: b3400, hsp15, yrfH, EG12929; ribosome-associated heat shock protein Hsp15 3782417 hlsR 3991407 hlsR Escherichia coli UTI89 ribosome-associated heat shock protein Hsp15 YP_542858.1 3782016 D 364106 CDS YP_542859.1 91212873 3991408 3782436..3783320 1 NC_007946.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 3783320 hslO 3991408 hslO Escherichia coli UTI89 heat shock protein 33 YP_542859.1 3782436 D 364106 CDS YP_542860.1 91212874 3991409 complement(3783383..3785107) 1 NC_007946.1 transport 3785107 yhgE 3991409 yhgE Escherichia coli UTI89 transport YP_542860.1 3783383 R 364106 CDS YP_542861.1 91212875 3991410 complement(3785113..3785241) 1 NC_007946.1 hypothetical protein 3785241 3991410 UTI89_C3901 Escherichia coli UTI89 hypothetical protein YP_542861.1 3785113 R 364106 CDS YP_542862.1 91212876 3991411 complement(3785183..3785314) 1 NC_007946.1 hypothetical protein 3785314 3991411 UTI89_C3902 Escherichia coli UTI89 hypothetical protein YP_542862.1 3785183 R 364106 CDS YP_542863.1 91212877 3991412 3785417..3787108 1 NC_007946.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3787108 pckA 3991412 pckA Escherichia coli UTI89 phosphoenolpyruvate carboxykinase YP_542863.1 3785417 D 364106 CDS YP_542864.1 91212878 3991413 complement(3787184..3788536) 1 NC_007946.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3788536 envZ 3991413 envZ Escherichia coli UTI89 osmolarity sensor protein YP_542864.1 3787184 R 364106 CDS YP_542865.1 91212879 3991414 complement(3788533..3789252) 1 NC_007946.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3789252 ompR 3991414 ompR Escherichia coli UTI89 osmolarity response regulator YP_542865.1 3788533 R 364106 CDS YP_542866.1 91212880 3991415 complement(3789342..3789527) 1 NC_007946.1 hypothetical protein 3789527 3991415 UTI89_C3906 Escherichia coli UTI89 hypothetical protein YP_542866.1 3789342 R 364106 CDS YP_542867.1 91212881 3991416 3789444..3789956 1 NC_007946.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3789956 greB 3991416 greB Escherichia coli UTI89 transcription elongation factor GreB YP_542867.1 3789444 D 364106 CDS YP_542868.1 91212882 3991417 3790053..3792374 1 NC_007946.1 hypothetical protein 3792374 yhgF 3991417 yhgF Escherichia coli UTI89 hypothetical protein YP_542868.1 3790053 D 364106 CDS YP_542869.1 91212883 3991418 3792814..3793041 1 NC_007946.1 ferrous iron transport protein A 3793041 feoA 3991418 feoA Escherichia coli UTI89 ferrous iron transport protein A YP_542869.1 3792814 D 364106 CDS YP_542870.1 91212884 3991419 3793046..3795379 1 NC_007946.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3795379 feoB 3991419 feoB Escherichia coli UTI89 ferrous iron transport protein B YP_542870.1 3793046 D 364106 CDS YP_542871.1 91212885 3991420 3795390..3795626 1 NC_007946.1 hypothetical protein 3795626 yhgG 3991420 yhgG Escherichia coli UTI89 hypothetical protein YP_542871.1 3795390 D 364106 CDS YP_542872.1 91212886 3994272 3795829..3796722 1 NC_007946.1 hypothetical protein 3796722 yhgA 3994272 yhgA Escherichia coli UTI89 hypothetical protein YP_542872.1 3795829 D 364106 CDS YP_542873.1 91212887 3994273 complement(3796942..3797712) 1 NC_007946.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3797712 bioH 3994273 bioH Escherichia coli UTI89 carboxylesterase BioH YP_542873.1 3796942 R 364106 CDS YP_542874.2 162138354 3994274 3797750..3798433 1 NC_007946.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3798433 yhgH 3994274 yhgH Escherichia coli UTI89 gluconate periplasmic binding protein YP_542874.2 3797750 D 364106 CDS YP_542875.1 91212889 3994275 3798492..3799067 1 NC_007946.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3799067 yhgI 3994275 yhgI Escherichia coli UTI89 DNA uptake protein YP_542875.1 3798492 D 364106 CDS YP_542876.1 91212890 3994276 3799428..3800744 1 NC_007946.1 high-affinitygluconate permease 3800744 gntT 3994276 gntT Escherichia coli UTI89 high-affinitygluconate permease YP_542876.1 3799428 D 364106 CDS YP_542877.1 91212891 3994277 complement(3800789..3802873) 1 NC_007946.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3802873 malQ 3994277 malQ Escherichia coli UTI89 4-alpha-glucanotransferase YP_542877.1 3800789 R 364106 CDS YP_542878.1 91212892 3994278 complement(3802883..3805276) 1 NC_007946.1 maltodextrin phosphorylase 3805276 malP 3994278 malP Escherichia coli UTI89 maltodextrin phosphorylase YP_542878.1 3802883 R 364106 CDS YP_542879.1 91212893 3994279 3805899..3808604 1 NC_007946.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3808604 malT 3994279 malT Escherichia coli UTI89 transcriptional regulator MalT YP_542879.1 3805899 D 364106 CDS YP_542880.1 91212894 3994280 complement(3808647..3809666) 1 NC_007946.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3809666 rtcA 3994280 rtcA Escherichia coli UTI89 RNA 3'-terminal-phosphate cyclase YP_542880.1 3808647 R 364106 CDS YP_542881.1 91212895 3994281 complement(3809667..3810956) 1 NC_007946.1 protein RtcB 3810956 rtcB 3994281 rtcB Escherichia coli UTI89 protein RtcB YP_542881.1 3809667 R 364106 CDS YP_542882.1 91212896 3994282 3811082..3812680 1 NC_007946.1 transcriptional regulator RtcR 3812680 rtcR 3994282 rtcR Escherichia coli UTI89 transcriptional regulator RtcR YP_542882.1 3811082 D 364106 CDS YP_542883.1 91212897 3994283 complement(3812662..3813471) 1 NC_007946.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3813471 glpR 3994283 glpR Escherichia coli UTI89 DNA-binding transcriptional repressor GlpR YP_542883.1 3812662 R 364106 CDS YP_542884.1 91212898 3994284 complement(3813437..3814267) 1 NC_007946.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3814267 glpG 3994284 glpG Escherichia coli UTI89 intramembrane serine protease GlpG YP_542884.1 3813437 R 364106 CDS YP_542885.1 91212899 3994285 complement(3814312..3814662) 1 NC_007946.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3814662 glpE 3994285 glpE Escherichia coli UTI89 thiosulfate sulfurtransferase YP_542885.1 3814312 R 364106 CDS YP_542886.2 162138353 3994286 3814828..3816333 1 NC_007946.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3816333 glpD 3994286 glpD Escherichia coli UTI89 glycerol-3-phosphate dehydrogenase YP_542886.2 3814828 D 364106 CDS YP_542887.1 91212901 3994287 complement(3816387..3816992) 1 NC_007946.1 hypothetical protein 3816992 3994287 UTI89_C3927 Escherichia coli UTI89 hypothetical protein YP_542887.1 3816387 R 364106 CDS YP_542888.1 91212902 3994288 complement(3816995..3817762) 1 NC_007946.1 hypothetical protein 3817762 3994288 UTI89_C3928 Escherichia coli UTI89 hypothetical protein YP_542888.1 3816995 R 364106 CDS YP_542889.1 91212903 3994289 complement(3817765..3818475) 1 NC_007946.1 hypothetical protein 3818475 aufG 3994289 aufG Escherichia coli UTI89 hypothetical protein YP_542889.1 3817765 R 364106 CDS YP_542890.1 91212904 3994290 complement(3819783..3820583) 1 NC_007946.1 Auf fimbrial chaperone 2 3820583 aufF 3994290 aufF Escherichia coli UTI89 Auf fimbrial chaperone 2 YP_542890.1 3819783 R 364106 CDS YP_542891.1 91212905 3994291 complement(3820528..3821085) 1 NC_007946.1 Auf fimbriae minor subunit AufE 3821085 aufE 3994291 aufE Escherichia coli UTI89 Auf fimbriae minor subunit AufE YP_542891.1 3820528 R 364106 CDS YP_542892.1 91212906 3993699 complement(3821051..3821500) 1 NC_007946.1 Auf fimbriae minor subunit AufD 3821500 aufD 3993699 aufD Escherichia coli UTI89 Auf fimbriae minor subunit AufD YP_542892.1 3821051 R 364106 CDS YP_542893.1 91212907 3993700 3821481..3821642 1 NC_007946.1 hypothetical protein 3821642 3993700 UTI89_C3933 Escherichia coli UTI89 hypothetical protein YP_542893.1 3821481 D 364106 CDS YP_542894.1 91212908 3993701 complement(3821614..3824208) 1 NC_007946.1 outer membrane usher protein AufC 3824208 aufC 3993701 aufC Escherichia coli UTI89 outer membrane usher protein AufC YP_542894.1 3821614 R 364106 CDS YP_542895.1 91212909 3993702 complement(3824245..3825024) 1 NC_007946.1 Auf fimbiral chaperone 1 3825024 aufB 3993702 aufB Escherichia coli UTI89 Auf fimbiral chaperone 1 YP_542895.1 3824245 R 364106 CDS YP_542896.1 91212910 3993703 complement(3825098..3825802) 1 NC_007946.1 Auf fimbriae major subunit AufA 3825802 aufA 3993703 aufA Escherichia coli UTI89 Auf fimbriae major subunit AufA YP_542896.1 3825098 R 364106 CDS YP_542897.1 91212911 3993704 complement(3826296..3828743) 1 NC_007946.1 glycogen phosphorylase 3828743 glgP 3993704 glgP Escherichia coli UTI89 glycogen phosphorylase YP_542897.1 3826296 R 364106 CDS YP_542898.1 91212912 3993705 complement(3828762..3830195) 1 NC_007946.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3830195 glgA 3993705 glgA Escherichia coli UTI89 glycogen synthase YP_542898.1 3828762 R 364106 CDS YP_542899.2 162138352 3993706 complement(3830195..3831490) 1 NC_007946.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3831490 glgC 3993706 glgC Escherichia coli UTI89 glucose-1-phosphate adenylyltransferase YP_542899.2 3830195 R 364106 CDS YP_542900.1 91212914 3993707 complement(3831508..3833481) 1 NC_007946.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme 3833481 glgX 3993707 glgX Escherichia coli UTI89 glycogen debranching enzyme YP_542900.1 3831508 R 364106 CDS YP_542901.1 91212915 3993708 complement(3833478..3835664) 1 NC_007946.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 3835664 glgB 3993708 glgB Escherichia coli UTI89 glycogen branching enzyme YP_542901.1 3833478 R 364106 CDS YP_542902.1 91212916 3993709 complement(3835937..3837100) 1 NC_007946.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3837100 asd 3993709 asd Escherichia coli UTI89 aspartate-semialdehyde dehydrogenase YP_542902.1 3835937 R 364106 CDS YP_542903.1 91212917 3993710 3837232..3837825 1 NC_007946.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3837825 yhgN 3993710 yhgN Escherichia coli UTI89 dITP- and XTP- hydrolase YP_542903.1 3837232 D 364106 CDS YP_542904.1 91212918 3993711 complement(3837882..3839222) 1 NC_007946.1 low affinity gluconate transporter 3839222 gntU 3993711 gntU Escherichia coli UTI89 low affinity gluconate transporter YP_542904.1 3837882 R 364106 CDS YP_542905.1 91212919 3993712 complement(3839226..3839774) 1 NC_007946.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 3839774 gntK 3993712 gntK Escherichia coli UTI89 gluconate kinase 1 YP_542905.1 3839226 R 364106 CDS YP_542906.1 91212920 3993713 complement(3839892..3840887) 1 NC_007946.1 gluconate utilization system GNT-I transcriptional repressor 3840887 gntR 3993713 gntR Escherichia coli UTI89 gluconate utilization system GNT-I transcriptional repressor YP_542906.1 3839892 R 364106 CDS YP_542907.1 91212921 3993714 complement(3840980..3841675) 1 NC_007946.1 hypothetical protein 3841675 yhhW 3993714 yhhW Escherichia coli UTI89 hypothetical protein YP_542907.1 3840980 R 364106 CDS YP_542908.1 91212922 3993715 complement(3841798..3842835) 1 NC_007946.1 dehydrogenase 3842835 yhhX 3993715 yhhX Escherichia coli UTI89 dehydrogenase YP_542908.1 3841798 R 364106 CDS YP_542909.1 91212923 3993716 3842782..3842940 1 NC_007946.1 hypothetical protein 3842940 3993716 UTI89_C3949 Escherichia coli UTI89 hypothetical protein YP_542909.1 3842782 D 364106 CDS YP_542910.1 91212924 3993717 complement(3842892..3843146) 1 NC_007946.1 hypothetical protein 3843146 3993717 UTI89_C3950 Escherichia coli UTI89 hypothetical protein YP_542910.1 3842892 R 364106 CDS YP_542911.1 91212925 3992892 3843169..3843657 1 NC_007946.1 YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3843657 3992892 UTI89_C3951 Escherichia coli UTI89 acetyltransferase YhhY YP_542911.1 3843169 D 364106 CDS YP_542912.1 91212926 3992893 3845068..3845562 1 NC_007946.1 hypothetical protein 3845562 yrhA 3992893 yrhA Escherichia coli UTI89 hypothetical protein YP_542912.1 3845068 D 364106 CDS YP_542913.1 91212927 3992894 3846012..3846296 1 NC_007946.1 hypothetical protein 3846296 yrhB 3992894 yrhB Escherichia coli UTI89 hypothetical protein YP_542913.1 3846012 D 364106 CDS YP_542914.1 91212928 3992895 complement(3846334..3848067) 1 NC_007946.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3848067 ggt 3992895 ggt Escherichia coli UTI89 gamma-glutamyltranspeptidase YP_542914.1 3846334 R 364106 CDS YP_542915.1 91212929 3992896 3848187..3848627 1 NC_007946.1 hypothetical protein 3848627 yhhA 3992896 yhhA Escherichia coli UTI89 hypothetical protein YP_542915.1 3848187 D 364106 CDS YP_542916.1 91212930 3992897 complement(3848614..3849357) 1 NC_007946.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase 3849357 ugpQ 3992897 ugpQ Escherichia coli UTI89 cytoplasmic glycerophosphodiester phosphodiesterase YP_542916.1 3848614 R 364106 CDS YP_542917.2 162138351 3992898 complement(3849354..3850424) 1 NC_007946.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3850424 ugpC 3992898 ugpC Escherichia coli UTI89 glycerol-3-phosphate transporter ATP-binding subunit YP_542917.2 3849354 R 364106 CDS YP_542918.1 91212932 3992899 complement(3850426..3851271) 1 NC_007946.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3851271 ugpE 3992899 ugpE Escherichia coli UTI89 glycerol-3-phosphate transporter membrane protein YP_542918.1 3850426 R 364106 CDS YP_542919.1 91212933 3992900 complement(3851268..3852155) 1 NC_007946.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3852155 ugpA 3992900 ugpA Escherichia coli UTI89 glycerol-3-phosphate transporter permease YP_542919.1 3851268 R 364106 CDS YP_542920.1 91212934 3992901 complement(3852253..3853569) 1 NC_007946.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3853569 ugpB 3992901 ugpB Escherichia coli UTI89 glycerol-3-phosphate transporter periplasmic binding protein YP_542920.1 3852253 R 364106 CDS YP_542921.2 162138350 3992902 complement(3853966..3854679) 1 NC_007946.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3854679 livF 3992902 livF Escherichia coli UTI89 leucine/isoleucine/valine transporter ATP-binding subunit YP_542921.2 3853966 R 364106 CDS YP_542922.1 91212936 3992903 complement(3854681..3855448) 1 NC_007946.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3855448 livG 3992903 livG Escherichia coli UTI89 leucine/isoleucine/valine transporter ATP-binding subunit YP_542922.1 3854681 R 364106 CDS YP_542923.1 91212937 3992904 complement(3855445..3856722) 1 NC_007946.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3856722 livM 3992904 livM Escherichia coli UTI89 leucine/isoleucine/valine transporter permease subunit YP_542923.1 3855445 R 364106 CDS YP_542924.1 91212938 3992905 complement(3856719..3857645) 1 NC_007946.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3857645 livH 3992905 livH Escherichia coli UTI89 branched-chain amino acid transporter permease subunit LivH YP_542924.1 3856719 R 364106 CDS YP_542925.1 91212939 3992906 complement(3857693..3858856) 1 NC_007946.1 leucine-specific binding protein 3858856 livK 3992906 livK Escherichia coli UTI89 leucine-specific binding protein YP_542925.1 3857693 R 364106 CDS YP_542926.1 91212940 3992907 complement(3858954..3859091) 1 NC_007946.1 hypothetical protein 3859091 3992907 UTI89_C3966 Escherichia coli UTI89 hypothetical protein YP_542926.1 3858954 R 364106 CDS YP_542927.1 91212941 3992908 3859226..3859609 1 NC_007946.1 acyltransferase 3859609 yhhK 3992908 yhhK Escherichia coli UTI89 acyltransferase YP_542927.1 3859226 D 364106 CDS YP_542928.1 91212942 3992909 3859619..3859741 1 NC_007946.1 hypothetical protein 3859741 3992909 UTI89_C3968 Escherichia coli UTI89 hypothetical protein YP_542928.1 3859619 D 364106 CDS YP_542929.1 91212943 3992910 complement(3859797..3860957) 1 NC_007946.1 Leu/Ile/Val-binding protein 3860957 livJ 3992910 livJ Escherichia coli UTI89 Leu/Ile/Val-binding protein YP_542929.1 3859797 R 364106 CDS YP_542930.1 91212944 3992911 3861904..3862236 1 NC_007946.1 phosphotransferase system protein 3862236 3992911 UTI89_C3970 Escherichia coli UTI89 phosphotransferase system protein YP_542930.1 3861904 D 364106 CDS YP_542931.1 91212945 3994077 3862243..3862728 1 NC_007946.1 phosphotransferase system protein 3862728 3994077 UTI89_C3971 Escherichia coli UTI89 phosphotransferase system protein YP_542931.1 3862243 D 364106 CDS YP_542932.1 91212946 3994078 3862745..3863491 1 NC_007946.1 phosphotransferase system protein 3863491 3994078 UTI89_C3972 Escherichia coli UTI89 phosphotransferase system protein YP_542932.1 3862745 D 364106 CDS YP_542933.1 91212947 3994079 3863628..3864338 1 NC_007946.1 phosphotransferase system protein 3864338 3994079 UTI89_C3973 Escherichia coli UTI89 phosphotransferase system protein YP_542933.1 3863628 D 364106 CDS YP_542934.1 91212948 3994080 3864340..3865260 1 NC_007946.1 phosphoglycerate dehydrogenase 3865260 3994080 UTI89_C3974 Escherichia coli UTI89 phosphoglycerate dehydrogenase YP_542934.1 3864340 D 364106 CDS YP_542935.1 91212949 3994081 3865260..3866144 1 NC_007946.1 dihydrodipicolinate synthase 3866144 3994081 UTI89_C3975 Escherichia coli UTI89 dihydrodipicolinate synthase YP_542935.1 3865260 D 364106 CDS YP_542936.1 91212950 3994082 complement(3866248..3867102) 1 NC_007946.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3867102 rpoH 3994082 rpoH Escherichia coli UTI89 RNA polymerase factor sigma-32 YP_542936.1 3866248 R 364106 CDS YP_542937.2 162138349 3994083 complement(3867347..3868405) 1 NC_007946.1 ABC transporter, membrane protein; cell division protein FtsX 3868405 ftsX 3994083 ftsX Escherichia coli UTI89 cell division protein FtsX YP_542937.2 3867347 R 364106 CDS YP_542938.1 91212952 3994084 complement(3868398..3869066) 1 NC_007946.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3869066 ftsE 3994084 ftsE Escherichia coli UTI89 cell division protein FtsE YP_542938.1 3868398 R 364106 CDS YP_542939.1 91212953 3994085 complement(3869069..3870565) 1 NC_007946.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3870565 ftsY 3994085 ftsY Escherichia coli UTI89 cell division protein FtsY YP_542939.1 3869069 R 364106 CDS YP_542940.1 91212954 3994086 3870715..3871311 1 NC_007946.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3871311 rsmD 3994086 rsmD Escherichia coli UTI89 16S rRNA m(2)G966-methyltransferase YP_542940.1 3870715 D 364106 CDS YP_542941.1 91212955 3994087 3871298..3871570 1 NC_007946.1 hypothetical protein 3871570 yhhL 3994087 yhhL Escherichia coli UTI89 hypothetical protein YP_542941.1 3871298 D 364106 CDS YP_542942.1 91212956 3994088 complement(3871573..3871932) 1 NC_007946.1 hypothetical protein 3871932 yhhM 3994088 yhhM Escherichia coli UTI89 hypothetical protein YP_542942.1 3871573 R 364106 CDS YP_542943.1 91212957 3994089 3872073..3872699 1 NC_007946.1 hypothetical protein 3872699 yhhN 3994089 yhhN Escherichia coli UTI89 hypothetical protein YP_542943.1 3872073 D 364106 CDS YP_542944.1 91212958 3994090 3872773..3874971 1 NC_007946.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3874971 zntA 3994090 zntA Escherichia coli UTI89 zinc/cadmium/mercury/lead-transporting ATPase YP_542944.1 3872773 D 364106 CDS YP_542945.1 91212959 3994091 3875201..3875503 1 NC_007946.1 hypothetical protein 3875503 3994091 UTI89_C3985 Escherichia coli UTI89 hypothetical protein YP_542945.1 3875201 D 364106 CDS YP_542946.1 91212960 3994092 complement(3875240..3875485) 1 NC_007946.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 3875485 sira 3994092 sira Escherichia coli UTI89 sulfur transfer protein SirA YP_542946.1 3875240 R 364106 CDS YP_542947.1 91212961 3994093 3875706..3876371 1 NC_007946.1 hypothetical protein 3876371 yhhQ 3994093 yhhQ Escherichia coli UTI89 hypothetical protein YP_542947.1 3875706 D 364106 CDS YP_542948.2 162138348 3994094 3876444..3877001 1 NC_007946.1 hypothetical protein 3877001 3994094 UTI89_C3988 Escherichia coli UTI89 hypothetical protein YP_542948.2 3876444 D 364106 CDS YP_542949.2 162138347 3994095 complement(3877005..3878222) 1 NC_007946.1 major facilitator superfamily transporter 3878222 yhhS 3994095 yhhS Escherichia coli UTI89 major facilitator superfamily transporter YP_542949.2 3877005 R 364106 CDS YP_542950.1 91212964 3991499 3878273..3879403 1 NC_007946.1 hypothetical protein 3879403 yhhT 3991499 yhhT Escherichia coli UTI89 hypothetical protein YP_542950.1 3878273 D 364106 CDS YP_542951.1 91212965 3991500 3879458..3880045 1 NC_007946.1 synonym: b3475, yhhU; holo-(acyl carrier protein) synthase 2 3880045 acpT 3991500 acpT Escherichia coli UTI89 holo-(acyl carrier protein) synthase 2 YP_542951.1 3879458 D 364106 CDS YP_542952.1 91212966 3991501 complement(3879955..3880131) 1 NC_007946.1 hypothetical protein 3880131 3991501 UTI89_C3992 Escherichia coli UTI89 hypothetical protein YP_542952.1 3879955 R 364106 CDS YP_542953.1 91212967 3991502 3880156..3881730 1 NC_007946.1 nickel-binding periplasmic protein 3881730 nikA 3991502 nikA Escherichia coli UTI89 nickel-binding periplasmic protein YP_542953.1 3880156 D 364106 CDS YP_542954.1 91212968 3991503 3881730..3882674 1 NC_007946.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3882674 nikB 3991503 nikB Escherichia coli UTI89 nickel transporter permease NikB YP_542954.1 3881730 D 364106 CDS YP_542955.1 91212969 3991504 3882671..3883504 1 NC_007946.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3883504 nikC 3991504 nikC Escherichia coli UTI89 nickel transporter permease NikC YP_542955.1 3882671 D 364106 CDS YP_542956.1 91212970 3991505 3883504..3884268 1 NC_007946.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3884268 nikD 3991505 nikD Escherichia coli UTI89 nickel transporter ATP-binding protein NikD YP_542956.1 3883504 D 364106 CDS YP_542957.1 91212971 3991506 3884265..3885071 1 NC_007946.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3885071 nikE 3991506 nikE Escherichia coli UTI89 nickel transporter ATP-binding protein NikE YP_542957.1 3884265 D 364106 CDS YP_542958.1 91212972 3991507 3885077..3885478 1 NC_007946.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3885478 nikR 3991507 nikR Escherichia coli UTI89 nickel responsive regulator YP_542958.1 3885077 D 364106 CDS YP_542959.1 91212973 3991508 3885668..3886423 1 NC_007946.1 regulator 3886423 3991508 UTI89_C3999 Escherichia coli UTI89 regulator YP_542959.1 3885668 D 364106 CDS YP_542960.1 91212974 3991509 3886448..3886921 1 NC_007946.1 phosphotransferase system enzyme subunit 3886921 3991509 UTI89_C4000 Escherichia coli UTI89 phosphotransferase system enzyme subunit YP_542960.1 3886448 D 364106 CDS YP_542961.1 91212975 3991510 3886918..3887199 1 NC_007946.1 phosphotransferase system enzyme subunit 3887199 3991510 UTI89_C4001 Escherichia coli UTI89 phosphotransferase system enzyme subunit YP_542961.1 3886918 D 364106 CDS YP_542962.1 91212976 3991511 3887246..3888634 1 NC_007946.1 PTS system galactitol-specific transporter subunit IIC 3888634 3991511 UTI89_C4002 Escherichia coli UTI89 PTS system galactitol-specific transporter subunit IIC YP_542962.1 3887246 D 364106 CDS YP_542963.1 91212977 3991512 3888627..3890135 1 NC_007946.1 xylulose kinase 3890135 3991512 UTI89_C4003 Escherichia coli UTI89 xylulose kinase YP_542963.1 3888627 D 364106 CDS YP_542964.1 91212978 3991513 3890125..3890394 1 NC_007946.1 phosphocarrier protein 3890394 3991513 UTI89_C4004 Escherichia coli UTI89 phosphocarrier protein YP_542964.1 3890125 D 364106 CDS YP_542965.1 91212979 3991514 3890426..3891277 1 NC_007946.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3891277 gatY 3991514 gatY Escherichia coli UTI89 fructose-1,6-bisphosphate aldolase YP_542965.1 3890426 D 364106 CDS YP_542966.1 91212980 3991515 complement(3891387..3892595) 1 NC_007946.1 hypothetical protein 3892595 yhhJ 3991515 yhhJ Escherichia coli UTI89 hypothetical protein YP_542966.1 3891387 R 364106 CDS YP_542967.1 91212981 3991516 complement(3892511..3895246) 1 NC_007946.1 ABC transporter ATP-binding protein 3895246 yhiH 3991516 yhiH Escherichia coli UTI89 ABC transporter ATP-binding protein YP_542967.1 3892511 R 364106 CDS YP_542968.1 91212982 3991517 complement(3895243..3896310) 1 NC_007946.1 hypothetical protein 3896310 yhiI 3991517 yhiI Escherichia coli UTI89 hypothetical protein YP_542968.1 3895243 R 364106 CDS YP_542969.1 91212983 3991518 complement(3896303..3896434) 1 NC_007946.1 hypothetical protein 3896434 3991518 UTI89_C4009 Escherichia coli UTI89 hypothetical protein YP_542969.1 3896303 R 364106 CDS YP_542970.1 91212984 3991241 3897032..3898096 1 NC_007946.1 hypothetical protein 3898096 yhiM 3991241 yhiM Escherichia coli UTI89 hypothetical protein YP_542970.1 3897032 D 364106 CDS YP_542971.1 91212985 3991242 complement(3898183..3899376) 1 NC_007946.1 hypothetical protein 3899376 yhiN 3991242 yhiN Escherichia coli UTI89 hypothetical protein YP_542971.1 3898183 R 364106 CDS YP_542972.1 91212986 3991243 3899608..3901107 1 NC_007946.1 low-affinity phosphate transport 3901107 pitA 3991243 pitA Escherichia coli UTI89 low-affinity phosphate transport YP_542972.1 3899608 D 364106 CDS YP_542973.1 91212987 3991244 complement(3901178..3901513) 1 NC_007946.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3901513 uspB 3991244 uspB Escherichia coli UTI89 universal stress protein UspB YP_542973.1 3901178 R 364106 CDS YP_542974.1 91212988 3991245 3901904..3902338 1 NC_007946.1 universal stress protein A 3902338 uspA 3991245 uspA Escherichia coli UTI89 universal stress protein A YP_542974.1 3901904 D 364106 CDS YP_542975.1 91212989 3991246 3902655..3904124 1 NC_007946.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3904124 yhiP 3991246 yhiP Escherichia coli UTI89 inner membrane transporter YhiP YP_542975.1 3902655 D 364106 CDS YP_542976.2 162138346 3991247 complement(3904173..3904925) 1 NC_007946.1 predicted SAM-dependent methyltransferase; methyltransferase 3904925 yhiQ 3991247 yhiQ Escherichia coli UTI89 methyltransferase YP_542976.2 3904173 R 364106 CDS YP_542977.1 91212991 3991248 complement(3904933..3907014) 1 NC_007946.1 synonym: b3498, opdA; oligopeptidase A 3907014 prlC 3991248 prlC Escherichia coli UTI89 oligopeptidase A YP_542977.1 3904933 R 364106 CDS YP_542978.1 91212992 3991249 3907127..3908020 1 NC_007946.1 hypothetical protein 3908020 yhiR 3991249 yhiR Escherichia coli UTI89 hypothetical protein YP_542978.1 3907127 D 364106 CDS YP_542979.1 91212993 3991250 3908092..3909444 1 NC_007946.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3909444 gor 3991250 gor Escherichia coli UTI89 glutathione reductase YP_542979.1 3908092 D 364106 CDS YP_542980.1 91212994 3991251 complement(3909498..3909647) 1 NC_007946.1 hypothetical protein 3909647 3991251 UTI89_C4020 Escherichia coli UTI89 hypothetical protein YP_542980.1 3909498 R 364106 CDS YP_542981.1 91212995 3991252 3910115..3910540 1 NC_007946.1 arsenate reductase 3910540 arsC 3991252 arsC Escherichia coli UTI89 arsenate reductase YP_542981.1 3910115 D 364106 CDS YP_542982.1 91212996 3991253 3910594..3910758 1 NC_007946.1 hypothetical protein 3910758 3991253 UTI89_C4022 Escherichia coli UTI89 hypothetical protein YP_542982.1 3910594 D 364106 CDS YP_542983.1 91212997 3991254 3911157..3911330 1 NC_007946.1 hypothetical protein 3911330 3991254 UTI89_C4023 Escherichia coli UTI89 hypothetical protein YP_542983.1 3911157 D 364106 CDS YP_542984.1 91212998 3991255 3911691..3912290 1 NC_007946.1 starvation induced outer membrane protein 3912290 slp 3991255 slp Escherichia coli UTI89 starvation induced outer membrane protein YP_542984.1 3911691 D 364106 CDS YP_542985.1 91212999 3991256 3912331..3912504 1 NC_007946.1 hypothetical protein 3912504 3991256 UTI89_C4025 Escherichia coli UTI89 hypothetical protein YP_542985.1 3912331 D 364106 CDS YP_542986.1 91213000 3991257 3912443..3912973 1 NC_007946.1 transcriptional regulator YhiF 3912973 yhiF 3991257 yhiF Escherichia coli UTI89 transcriptional regulator YhiF YP_542986.1 3912443 D 364106 CDS YP_542987.1 91213001 3991258 complement(3913030..3914058) 1 NC_007946.1 heme/hemoglobin transport protein 3914058 chuS 3991258 chuS Escherichia coli UTI89 heme/hemoglobin transport protein YP_542987.1 3913030 R 364106 CDS YP_542988.1 91213002 3991259 complement(3914107..3916089) 1 NC_007946.1 outer membrane hemin receptor ChuA 3916089 chuA 3991259 chuA Escherichia coli UTI89 outer membrane hemin receptor ChuA YP_542988.1 3914107 R 364106 CDS YP_542989.1 91213003 3990017 3916028..3916186 1 NC_007946.1 hypothetical protein 3916186 3990017 UTI89_C4029 Escherichia coli UTI89 hypothetical protein YP_542989.1 3916028 D 364106 CDS YP_542990.1 91213004 3990018 complement(3916190..3916375) 1 NC_007946.1 hypothetical protein 3916375 3990018 UTI89_C4030 Escherichia coli UTI89 hypothetical protein YP_542990.1 3916190 R 364106 CDS YP_542991.1 91213005 3990019 3916458..3916619 1 NC_007946.1 hypothetical protein 3916619 3990019 UTI89_C4031 Escherichia coli UTI89 hypothetical protein YP_542991.1 3916458 D 364106 CDS YP_542992.1 91213006 3990020 complement(3916501..3916650) 1 NC_007946.1 hypothetical protein 3916650 3990020 UTI89_C4032 Escherichia coli UTI89 hypothetical protein YP_542992.1 3916501 R 364106 CDS YP_542993.1 91213007 3990021 3916695..3917687 1 NC_007946.1 periplasmic binding protein 3917687 chuT 3990021 chuT Escherichia coli UTI89 periplasmic binding protein YP_542993.1 3916695 D 364106 CDS YP_542994.1 91213008 3990022 3917707..3919044 1 NC_007946.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3919044 chuW 3990022 chuW Escherichia coli UTI89 coproporphyrinogen III oxidase YP_542994.1 3917707 D 364106 CDS YP_542995.1 91213009 3990023 3919057..3919551 1 NC_007946.1 hypothetical protein 3919551 chuX 3990023 chuX Escherichia coli UTI89 hypothetical protein YP_542995.1 3919057 D 364106 CDS YP_542996.1 91213010 3990024 3919551..3920174 1 NC_007946.1 hypothetical protein 3920174 chuY 3990024 chuY Escherichia coli UTI89 hypothetical protein YP_542996.1 3919551 D 364106 CDS YP_542997.1 91213011 3990025 3920223..3921215 1 NC_007946.1 permease of iron compound ABC transport system 3921215 chuU 3990025 chuU Escherichia coli UTI89 permease of iron compound ABC transport system YP_542997.1 3920223 D 364106 CDS YP_542998.1 91213012 3990026 3921182..3921982 1 NC_007946.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3921982 hmuV 3990026 hmuV Escherichia coli UTI89 hemin importer ATP-binding subunit YP_542998.1 3921182 D 364106 CDS YP_542999.1 91213013 3990027 complement(3922034..3922681) 1 NC_007946.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 3922681 yhiD 3990027 yhiD Escherichia coli UTI89 Mg(2+) transport ATPase YP_542999.1 3922034 R 364106 CDS YP_543000.1 91213014 3990028 complement(3922745..3923083) 1 NC_007946.1 acid-resistance protein 3923083 hdeB 3990028 hdeB Escherichia coli UTI89 acid-resistance protein YP_543000.1 3922745 R 364106 CDS YP_543001.1 91213015 3990029 complement(3923187..3923519) 1 NC_007946.1 inactive form; acid-resistance protein 3923519 hdeA 3990029 hdeA Escherichia coli UTI89 acid-resistance protein YP_543001.1 3923187 R 364106 CDS YP_543002.1 91213016 3990030 3923774..3924346 1 NC_007946.1 acid-resistance membrane protein 3924346 hdeD 3990030 hdeD Escherichia coli UTI89 acid-resistance membrane protein YP_543002.1 3923774 D 364106 CDS YP_543003.1 91213017 3990031 3925067..3925672 1 NC_007946.1 hypothetical protein 3925672 yhiE 3990031 yhiE Escherichia coli UTI89 hypothetical protein YP_543003.1 3925067 D 364106 CDS YP_543004.1 91213018 3990032 3925716..3926009 1 NC_007946.1 hypothetical protein 3926009 3990032 UTI89_C4044 Escherichia coli UTI89 hypothetical protein YP_543004.1 3925716 D 364106 CDS YP_543005.1 91213019 3990033 3926011..3927168 1 NC_007946.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3927168 yhiU 3990033 yhiU Escherichia coli UTI89 multidrug efflux system protein MdtE YP_543005.1 3926011 D 364106 CDS YP_543006.1 91213020 3990034 3927193..3930306 1 NC_007946.1 hypothetical protein 3930306 yhiV 3990034 yhiV Escherichia coli UTI89 hypothetical protein YP_543006.1 3927193 D 364106 CDS YP_543007.1 91213021 3990035 complement(3930669..3931397) 1 NC_007946.1 transcriptional regulator YhiW 3931397 yhiW 3990035 yhiW Escherichia coli UTI89 transcriptional regulator YhiW YP_543007.1 3930669 R 364106 CDS YP_543008.1 91213022 3990036 complement(3931766..3932590) 1 NC_007946.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3932590 yhiX 3990036 yhiX Escherichia coli UTI89 DNA-binding transcriptional regulator GadX YP_543008.1 3931766 R 364106 CDS YP_543009.1 91213023 3991128 complement(3932958..3934421) 1 NC_007946.1 glutamate decarboxylase alpha 3934421 gadA 3991128 gadA Escherichia coli UTI89 glutamate decarboxylase alpha YP_543009.1 3932958 R 364106 CDS YP_543010.1 91213024 3991129 complement(3934569..3935966) 1 NC_007946.1 cytochrome C peroxidase 3935966 yhjA 3991129 yhjA Escherichia coli UTI89 cytochrome C peroxidase YP_543010.1 3934569 R 364106 CDS YP_543011.1 91213025 3991130 3936371..3938020 1 NC_007946.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3938020 treF 3991130 treF Escherichia coli UTI89 trehalase YP_543011.1 3936371 D 364106 CDS YP_543012.1 91213026 3991131 complement(3938071..3938673) 1 NC_007946.1 transcriptional regulator YhjB 3938673 yhjB 3991131 yhjB Escherichia coli UTI89 transcriptional regulator YhjB YP_543012.1 3938071 R 364106 CDS YP_543013.1 91213027 3991132 3939121..3940092 1 NC_007946.1 transcriptional regulator YhjC 3940092 yhjC 3991132 yhjC Escherichia coli UTI89 transcriptional regulator YhjC YP_543013.1 3939121 D 364106 CDS YP_543014.1 91213028 3991133 3940141..3941154 1 NC_007946.1 hypothetical protein 3941154 yhjD 3991133 yhjD Escherichia coli UTI89 hypothetical protein YP_543014.1 3940141 D 364106 CDS YP_543015.1 91213029 3991134 3941547..3942869 1 NC_007946.1 metabolite transport protein YhjE 3942869 yhjE 3991134 yhjE Escherichia coli UTI89 metabolite transport protein YhjE YP_543015.1 3941547 D 364106 CDS YP_543016.1 91213030 3991135 complement(3942910..3944985) 1 NC_007946.1 hypothetical protein 3944985 yhjG 3991135 yhjG Escherichia coli UTI89 hypothetical protein YP_543016.1 3942910 R 364106 CDS YP_543017.1 91213031 3991136 complement(3945040..3945810) 1 NC_007946.1 in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase 3945810 yhjH 3991136 yhjH Escherichia coli UTI89 diguanylate phosphodiesterase YP_543017.1 3945040 R 364106 CDS YP_543018.1 91213032 3991137 3945691..3946968 1 NC_007946.1 2-dehydro-3-deoxygluconokinase 3946968 kdgK 3991137 kdgK Escherichia coli UTI89 2-dehydro-3-deoxygluconokinase YP_543018.1 3945691 D 364106 CDS YP_543019.1 91213033 3991138 complement(3947064..3948560) 1 NC_007946.1 protein YhjJ 3948560 yhjJ 3991138 yhjJ Escherichia coli UTI89 protein YhjJ YP_543019.1 3947064 R 364106 CDS YP_543020.1 91213034 3991139 complement(3948780..3950066) 1 NC_007946.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 3950066 dctA 3991139 dctA Escherichia coli UTI89 C4-dicarboxylate transporter DctA YP_543020.1 3948780 R 364106 CDS YP_543021.1 91213035 3991140 complement(3950249..3952237) 1 NC_007946.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase 3952237 yhjK 3991140 yhjK Escherichia coli UTI89 phosphodiesterase YP_543021.1 3950249 R 364106 CDS YP_543022.1 91213036 3991141 complement(3952319..3955792) 1 NC_007946.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 3955792 yhjL 3991141 yhjL Escherichia coli UTI89 cellulose synthase subunit BcsC YP_543022.1 3952319 R 364106 CDS YP_543023.1 91213037 3991142 complement(3955774..3956886) 1 NC_007946.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 3956886 yhjM 3991142 yhjM Escherichia coli UTI89 endo-1,4-D-glucanase YP_543023.1 3955774 R 364106 CDS YP_543024.1 91213038 3991143 complement(3956887..3959313) 1 NC_007946.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 3959313 yhjN 3991143 yhjN Escherichia coli UTI89 cellulose synthase regulator protein YP_543024.1 3956887 R 364106 CDS YP_543025.2 162138345 3991144 complement(3959237..3961855) 1 NC_007946.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 3961855 bcsA 3991144 bcsA Escherichia coli UTI89 cellulose synthase catalytic subunit YP_543025.2 3959237 R 364106 CDS YP_543026.1 91213040 3991145 complement(3961852..3962604) 1 NC_007946.1 cell division protein 3962604 yhjQ 3991145 yhjQ Escherichia coli UTI89 cell division protein YP_543026.1 3961852 R 364106 CDS YP_543027.1 91213041 3991146 complement(3962616..3962804) 1 NC_007946.1 hypothetical protein 3962804 yhjR 3991146 yhjR Escherichia coli UTI89 hypothetical protein YP_543027.1 3962616 R 364106 CDS YP_543028.1 91213042 3989626 3963077..3964648 1 NC_007946.1 hypothetical protein 3964648 yhjS 3989626 yhjS Escherichia coli UTI89 hypothetical protein YP_543028.1 3963077 D 364106 CDS YP_543029.1 91213043 3989627 3964645..3964836 1 NC_007946.1 hypothetical protein 3964836 yhjT 3989627 yhjT Escherichia coli UTI89 hypothetical protein YP_543029.1 3964645 D 364106 CDS YP_543030.1 91213044 3989628 3964833..3966512 1 NC_007946.1 hypothetical protein 3966512 yhjU 3989628 yhjU Escherichia coli UTI89 hypothetical protein YP_543030.1 3964833 D 364106 CDS YP_543031.1 91213045 3989629 complement(3966598..3966840) 1 NC_007946.1 hypothetical protein 3966840 3989629 UTI89_C4071 Escherichia coli UTI89 hypothetical protein YP_543031.1 3966598 R 364106 CDS YP_543032.1 91213046 3989630 3966777..3967076 1 NC_007946.1 hypothetical protein 3967076 3989630 UTI89_C4072 Escherichia coli UTI89 hypothetical protein YP_543032.1 3966777 D 364106 CDS YP_543033.1 91213047 3989631 complement(3967081..3967323) 1 NC_007946.1 hypothetical protein 3967323 3989631 UTI89_C4073 Escherichia coli UTI89 hypothetical protein YP_543033.1 3967081 R 364106 CDS YP_543034.1 91213048 3989632 3967230..3967547 1 NC_007946.1 hypothetical protein 3967547 3989632 UTI89_C4074 Escherichia coli UTI89 hypothetical protein YP_543034.1 3967230 D 364106 CDS YP_543035.1 91213049 3989633 complement(3967563..3967838) 1 NC_007946.1 hypothetical protein 3967838 3989633 UTI89_C4075 Escherichia coli UTI89 hypothetical protein YP_543035.1 3967563 R 364106 CDS YP_543036.1 91213050 3989634 complement(3967835..3967996) 1 NC_007946.1 hypothetical protein 3967996 3989634 UTI89_C4076 Escherichia coli UTI89 hypothetical protein YP_543036.1 3967835 R 364106 CDS YP_543037.1 91213051 3989635 3968083..3969417 1 NC_007946.1 transport protein YhjV 3969417 yhjV 3989635 yhjV Escherichia coli UTI89 transport protein YhjV YP_543037.1 3968083 D 364106 CDS YP_543038.1 91213052 3989636 complement(3969447..3970451) 1 NC_007946.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 3970451 dppF 3989636 dppF Escherichia coli UTI89 dipeptide transporter ATP-binding subunit YP_543038.1 3969447 R 364106 CDS YP_543039.1 91213053 3989637 complement(3970448..3971431) 1 NC_007946.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 3971431 dppD 3989637 dppD Escherichia coli UTI89 dipeptide transporter ATP-binding subunit YP_543039.1 3970448 R 364106 CDS YP_543040.1 91213054 3989638 complement(3971442..3972344) 1 NC_007946.1 dipeptide transporter 3972344 dppC 3989638 dppC Escherichia coli UTI89 dipeptide transporter YP_543040.1 3971442 R 364106 CDS YP_543041.1 91213055 3989639 complement(3972354..3973373) 1 NC_007946.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 3973373 dppB 3989639 dppB Escherichia coli UTI89 dipeptide transporter permease DppB YP_543041.1 3972354 R 364106 CDS YP_543042.1 91213056 3989640 complement(3973524..3975131) 1 NC_007946.1 periplasmic dipeptide transport protein 3975131 dppA 3989640 dppA Escherichia coli UTI89 periplasmic dipeptide transport protein YP_543042.1 3973524 R 364106 CDS YP_543043.1 91213057 3989641 3975320..3975475 1 NC_007946.1 hypothetical protein 3975475 3989641 UTI89_C4083 Escherichia coli UTI89 hypothetical protein YP_543043.1 3975320 D 364106 CDS YP_543045.2 162138344 3989644 complement(3976040..3977731) 1 NC_007946.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 3977731 yhjW 3989644 yhjW Escherichia coli UTI89 phosphoethanolamine transferase YP_543045.2 3976040 R 364106 CDS YP_543046.1 91213060 3991260 complement(3978055..3979308) 1 NC_007946.1 resistance protein 3979308 yhjX 3991260 yhjX Escherichia coli UTI89 resistance protein YP_543046.1 3978055 R 364106 CDS YP_543047.1 91213061 3991261 complement(3979492..3980196) 1 NC_007946.1 hypothetical protein 3980196 yhjY 3991261 yhjY Escherichia coli UTI89 hypothetical protein YP_543047.1 3979492 R 364106 CDS YP_543048.2 162138343 3991262 3980348..3980911 1 NC_007946.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 3980911 tag 3991262 tag Escherichia coli UTI89 3-methyl-adenine DNA glycosylase I YP_543048.2 3980348 D 364106 CDS YP_543049.1 91213063 3991263 3980908..3981348 1 NC_007946.1 hypothetical protein 3981348 yiaC 3991263 yiaC Escherichia coli UTI89 hypothetical protein YP_543049.1 3980908 D 364106 CDS YP_543050.1 91213064 3991264 complement(3981317..3983650) 1 NC_007946.1 biotin sulfoxide reductase 3983650 bisC 3991264 bisC Escherichia coli UTI89 biotin sulfoxide reductase YP_543050.1 3981317 R 364106 CDS YP_543051.1 91213065 3991265 3983803..3984462 1 NC_007946.1 outer membrane lipoprotein 3984462 yiaD 3991265 yiaD Escherichia coli UTI89 outer membrane lipoprotein YP_543051.1 3983803 D 364106 CDS YP_543052.1 91213066 3991266 3984554..3985540 1 NC_007946.1 dehydrogenase 3985540 yiaE 3991266 yiaE Escherichia coli UTI89 dehydrogenase YP_543052.1 3984554 D 364106 CDS YP_543053.1 91213067 3991267 complement(3985590..3986420) 1 NC_007946.1 hypothetical protein 3986420 yiaF 3991267 yiaF Escherichia coli UTI89 hypothetical protein YP_543053.1 3985590 R 364106 CDS YP_543054.1 91213068 3991268 3986734..3987024 1 NC_007946.1 transcriptional regulator 3987024 yiaG 3991268 yiaG Escherichia coli UTI89 transcriptional regulator YP_543054.1 3986734 D 364106 CDS YP_543055.1 91213069 3991269 complement(3987242..3987664) 1 NC_007946.1 hypothetical protein 3987664 3991269 UTI89_C4096 Escherichia coli UTI89 hypothetical protein YP_543055.1 3987242 R 364106 CDS YP_543056.1 91213070 3991270 3987305..3987517 1 NC_007946.1 cold-shock protein 3987517 cspA 3991270 cspA Escherichia coli UTI89 cold-shock protein YP_543056.1 3987305 D 364106 CDS YP_543057.1 91213071 3991271 complement(3987705..3987917) 1 NC_007946.1 small toxic polypeptide 3987917 3991271 UTI89_C4098 Escherichia coli UTI89 small toxic polypeptide YP_543057.1 3987705 R 364106 CDS YP_543058.1 91213072 3991272 complement(3988180..3990249) 1 NC_007946.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 3990249 glyS 3991272 glyS Escherichia coli UTI89 glycyl-tRNA synthetase subunit beta YP_543058.1 3988180 R 364106 CDS YP_543059.1 91213073 3991273 complement(3990259..3991170) 1 NC_007946.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 3991170 glyQ 3991273 glyQ Escherichia coli UTI89 glycyl-tRNA synthetase subunit alpha YP_543059.1 3990259 R 364106 CDS YP_543060.1 91213074 3991274 complement(3991265..3991564) 1 NC_007946.1 hypothetical protein 3991564 3991274 UTI89_C4101 Escherichia coli UTI89 hypothetical protein YP_543060.1 3991265 R 364106 CDS YP_543061.1 91213075 3991275 3991739..3992734 1 NC_007946.1 hypothetical protein 3992734 yiaH 3991275 yiaH Escherichia coli UTI89 hypothetical protein YP_543061.1 3991739 D 364106 CDS YP_543062.1 91213076 3991276 complement(3992776..3993216) 1 NC_007946.1 hypothetical protein 3993216 yiaA 3991276 yiaA Escherichia coli UTI89 hypothetical protein YP_543062.1 3992776 R 364106 CDS YP_543063.1 91213077 3991277 complement(3993259..3993642) 1 NC_007946.1 hypothetical protein 3993642 yiaB 3991277 yiaB Escherichia coli UTI89 hypothetical protein YP_543063.1 3993259 R 364106 CDS YP_543064.1 91213078 3991278 complement(3993769..3995223) 1 NC_007946.1 xylulokinase 3995223 xylB 3991278 xylB Escherichia coli UTI89 xylulokinase YP_543064.1 3993769 R 364106 CDS YP_543065.2 162138342 3993812 complement(3995295..3996617) 1 NC_007946.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 3996617 xylA 3993812 xylA Escherichia coli UTI89 xylose isomerase YP_543065.2 3995295 R 364106 CDS YP_543066.1 91213080 3993813 3996905..3997975 1 NC_007946.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3997975 xylF 3993813 xylF Escherichia coli UTI89 D-xylose transporter subunit XylF YP_543066.1 3996905 D 364106 CDS YP_543067.1 91213081 3993814 3998017..3999594 1 NC_007946.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3999594 xylG 3993814 xylG Escherichia coli UTI89 xylose transporter ATP-binding subunit YP_543067.1 3998017 D 364106 CDS YP_543068.1 91213082 3993815 3999572..4000753 1 NC_007946.1 xylose transport system permease xylH 4000753 xylH 3993815 xylH Escherichia coli UTI89 xylose transport system permease xylH YP_543068.1 3999572 D 364106 CDS YP_543069.1 91213083 3993816 4000831..4002009 1 NC_007946.1 regulator of xyl operon 4002009 xylR 3993816 xylR Escherichia coli UTI89 regulator of xyl operon YP_543069.1 4000831 D 364106 CDS YP_543070.1 91213084 3993817 complement(4002117..4002941) 1 NC_007946.1 hypothetical protein 4002941 bax 3993817 bax Escherichia coli UTI89 hypothetical protein YP_543070.1 4002117 R 364106 CDS YP_543071.1 91213085 3993818 4003091..4003264 1 NC_007946.1 hypothetical protein 4003264 3993818 UTI89_C4112 Escherichia coli UTI89 hypothetical protein YP_543071.1 4003091 D 364106 CDS YP_543072.1 91213086 3993819 4003261..4005291 1 NC_007946.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4005291 malS 3993819 malS Escherichia coli UTI89 periplasmic alpha-amylase YP_543072.1 4003261 D 364106 CDS YP_543073.1 91213087 3993820 4005364..4006722 1 NC_007946.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4006722 avtA 3993820 avtA Escherichia coli UTI89 valine--pyruvate transaminase YP_543073.1 4005364 D 364106 CDS YP_543074.1 91213088 3993821 complement(4006874..4007353) 1 NC_007946.1 synonym: yiaI, b3573; electron transport protein YsaA 4007353 ysaA 3993821 ysaA Escherichia coli UTI89 electron transport protein YsaA YP_543074.1 4006874 R 364106 CDS YP_543075.1 91213089 3993822 complement(4007449..4008297) 1 NC_007946.1 transcriptional regulator YiaJ 4008297 yiaJ 3993822 yiaJ Escherichia coli UTI89 transcriptional regulator YiaJ YP_543075.1 4007449 R 364106 CDS YP_543076.1 91213090 3993823 4008498..4009496 1 NC_007946.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4009496 yiaK 3993823 yiaK Escherichia coli UTI89 2,3-diketo-L-gulonate reductase YP_543076.1 4008498 D 364106 CDS YP_543077.1 91213091 3993824 4009508..4009972 1 NC_007946.1 hypothetical protein 4009972 yiaL 3993824 yiaL Escherichia coli UTI89 hypothetical protein YP_543077.1 4009508 D 364106 CDS YP_543078.1 91213092 3993825 4009995..4010915 1 NC_007946.1 hypothetical protein 4010915 3993825 UTI89_C4119 Escherichia coli UTI89 hypothetical protein YP_543078.1 4009995 D 364106 CDS YP_543079.1 91213093 3993826 4011029..4011496 1 NC_007946.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 4011496 yiaM 3993826 yiaM Escherichia coli UTI89 2,3-diketo-L-gulonate TRAP transporter small permease YiaM YP_543079.1 4011029 D 364106 CDS YP_543080.1 91213094 3993827 4011499..4012776 1 NC_007946.1 hypothetical protein 4012776 yiaN 3993827 yiaN Escherichia coli UTI89 hypothetical protein YP_543080.1 4011499 D 364106 CDS YP_543081.1 91213095 3993828 4012764..4012886 1 NC_007946.1 hypothetical protein 4012886 3993828 UTI89_C4122 Escherichia coli UTI89 hypothetical protein YP_543081.1 4012764 D 364106 CDS YP_543082.1 91213096 3993829 4012789..4013775 1 NC_007946.1 ABC transporter periplasmic binding protein yiaO 4013775 yiaO 3993829 yiaO Escherichia coli UTI89 ABC transporter periplasmic binding protein yiaO YP_543082.1 4012789 D 364106 CDS YP_543083.1 91213097 3993830 4013779..4015275 1 NC_007946.1 cryptic L-xylulose kinase 4015275 lyxK 3993830 lyxK Escherichia coli UTI89 cryptic L-xylulose kinase YP_543083.1 4013779 D 364106 CDS YP_543084.1 91213098 3993831 4015272..4015934 1 NC_007946.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4015934 sgbH 3993831 sgbH Escherichia coli UTI89 3-keto-L-gulonate-6-phosphate decarboxylase YP_543084.1 4015272 D 364106 CDS YP_543085.1 91213099 3991013 4015894..4016787 1 NC_007946.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4016787 sgbU 3991013 sgbU Escherichia coli UTI89 L-xylulose 5-phosphate 3-epimerase YP_543085.1 4015894 D 364106 CDS YP_543086.1 91213100 3991014 4016781..4017476 1 NC_007946.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4017476 sgbE 3991014 sgbE Escherichia coli UTI89 L-ribulose-5-phosphate 4-epimerase YP_543086.1 4016781 D 364106 CDS YP_543087.1 91213101 3991015 complement(4016784..4017521) 1 NC_007946.1 hypothetical protein 4017521 3991015 UTI89_C4128 Escherichia coli UTI89 hypothetical protein YP_543087.1 4016784 R 364106 CDS YP_543088.1 91213102 3991016 complement(4017523..4019151) 1 NC_007946.1 aldehyde dehydrogenase 4019151 aldB 3991016 aldB Escherichia coli UTI89 aldehyde dehydrogenase YP_543088.1 4017523 R 364106 CDS YP_543089.1 91213103 3991017 complement(4019169..4020464) 1 NC_007946.1 hypothetical protein 4020464 3991017 UTI89_C4130 Escherichia coli UTI89 hypothetical protein YP_543089.1 4019169 R 364106 CDS YP_543090.1 91213104 3991018 complement(4020594..4021745) 1 NC_007946.1 alcohol dehydrogenase 4021745 yiaY 3991018 yiaY Escherichia coli UTI89 alcohol dehydrogenase YP_543090.1 4020594 R 364106 CDS YP_543091.1 91213105 3991019 complement(4021936..4023780) 1 NC_007946.1 selenocysteinyl-tRNA-specific translation factor 4023780 selB 3991019 selB Escherichia coli UTI89 selenocysteinyl-tRNA-specific translation factor YP_543091.1 4021936 R 364106 CDS YP_543092.1 91213106 3991020 complement(4023777..4025168) 1 NC_007946.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4025168 selA 3991020 selA Escherichia coli UTI89 selenocysteine synthase YP_543092.1 4023777 R 364106 CDS YP_543093.1 91213107 3991021 complement(4025266..4025874) 1 NC_007946.1 glutathione S-transferase 4025874 yibF 3991021 yibF Escherichia coli UTI89 glutathione S-transferase YP_543093.1 4025266 R 364106 CDS YP_543094.1 91213108 3991022 complement(4025945..4027081) 1 NC_007946.1 hypothetical protein 4027081 yibH 3991022 yibH Escherichia coli UTI89 hypothetical protein YP_543094.1 4025945 R 364106 CDS YP_543095.1 91213109 3991023 complement(4027084..4027446) 1 NC_007946.1 hypothetical protein 4027446 yibI 3991023 yibI Escherichia coli UTI89 hypothetical protein YP_543095.1 4027084 R 364106 CDS YP_543096.1 91213110 3991024 4027982..4029895 1 NC_007946.1 mannitol-specific PTS system enzyme IIABC components 4029895 mtlA 3991024 mtlA Escherichia coli UTI89 mannitol-specific PTS system enzyme IIABC components YP_543096.1 4027982 D 364106 CDS YP_543097.1 91213111 3991025 4030034..4031362 1 NC_007946.1 mannitol-1-phosphate 5-dehydrogenase 4031362 mtlD 3991025 mtlD Escherichia coli UTI89 mannitol-1-phosphate 5-dehydrogenase YP_543097.1 4030034 D 364106 CDS YP_543098.1 91213112 3991026 4031362..4031949 1 NC_007946.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4031949 mtlR 3991026 mtlR Escherichia coli UTI89 mannitol repressor protein YP_543098.1 4031362 D 364106 CDS YP_543099.1 91213113 3991027 complement(4031960..4032169) 1 NC_007946.1 hypothetical protein 4032169 3991027 UTI89_C4140 Escherichia coli UTI89 hypothetical protein YP_543099.1 4031960 R 364106 CDS YP_543100.1 91213114 3991028 4032453..4032815 1 NC_007946.1 hypothetical protein 4032815 yibL 3991028 yibL Escherichia coli UTI89 hypothetical protein YP_543100.1 4032453 D 364106 CDS YP_543101.1 91213115 3991029 complement(4033071..4033238) 1 NC_007946.1 hypothetical protein 4033238 3991029 UTI89_C4142 Escherichia coli UTI89 hypothetical protein YP_543101.1 4033071 R 364106 CDS YP_543102.1 91213116 3991030 4034101..4038852 1 NC_007946.1 autotransport adhesin 4038852 3991030 UTI89_C4143 Escherichia coli UTI89 autotransport adhesin YP_543102.1 4034101 D 364106 CDS YP_543103.1 91213117 3991031 4039241..4040917 1 NC_007946.1 L-lactate permease 4040917 lldP 3991031 lldP Escherichia coli UTI89 L-lactate permease YP_543103.1 4039241 D 364106 CDS YP_543104.1 91213118 3989606 4040902..4041693 1 NC_007946.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4041693 lldR 3989606 lldR Escherichia coli UTI89 DNA-binding transcriptional repressor LldR YP_543104.1 4040902 D 364106 CDS YP_543105.1 91213119 3989607 4041690..4042880 1 NC_007946.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4042880 lldD 3989607 lldD Escherichia coli UTI89 L-lactate dehydrogenase YP_543105.1 4041690 D 364106 CDS YP_543106.1 91213120 3989608 4042928..4043401 1 NC_007946.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4043401 yibK 3989608 yibK Escherichia coli UTI89 tRNA/rRNA methyltransferase YibK YP_543106.1 4042928 D 364106 CDS YP_543107.1 91213121 3989609 complement(4043456..4044277) 1 NC_007946.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4044277 cysE 3989609 cysE Escherichia coli UTI89 serine acetyltransferase YP_543107.1 4043456 R 364106 CDS YP_543108.1 91213122 3989610 complement(4044357..4045376) 1 NC_007946.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4045376 gpsA 3989610 gpsA Escherichia coli UTI89 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_543108.1 4044357 R 364106 CDS YP_543109.1 91213123 3989611 4045355..4045840 1 NC_007946.1 hypothetical protein 4045840 3989611 UTI89_C4150 Escherichia coli UTI89 hypothetical protein YP_543109.1 4045355 D 364106 CDS YP_543110.1 91213124 3989612 complement(4045376..4045903) 1 NC_007946.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4045903 secB 3989612 secB Escherichia coli UTI89 preprotein translocase subunit SecB YP_543110.1 4045376 R 364106 CDS YP_543111.1 91213125 3989613 complement(4045907..4046158) 1 NC_007946.1 glutaredoxin 3 4046158 grxC 3989613 grxC Escherichia coli UTI89 glutaredoxin 3 YP_543111.1 4045907 R 364106 CDS YP_543112.1 91213126 3989614 4045973..4046242 1 NC_007946.1 hypothetical protein 4046242 3989614 UTI89_C4153 Escherichia coli UTI89 hypothetical protein YP_543112.1 4045973 D 364106 CDS YP_543113.1 91213127 3989615 complement(4046255..4046413) 1 NC_007946.1 hypothetical protein 4046413 3989615 UTI89_C4154 Escherichia coli UTI89 hypothetical protein YP_543113.1 4046255 R 364106 CDS YP_543114.1 91213128 3989616 complement(4046299..4046742) 1 NC_007946.1 hypothetical protein 4046742 yibN 3989616 yibN Escherichia coli UTI89 hypothetical protein YP_543114.1 4046299 R 364106 CDS YP_543115.1 91213129 3989617 4046754..4046951 1 NC_007946.1 hypothetical protein 4046951 3989617 UTI89_C4156 Escherichia coli UTI89 hypothetical protein YP_543115.1 4046754 D 364106 CDS YP_543116.2 162138341 3989618 4046975..4048519 1 NC_007946.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4048519 yibO 3989618 yibO Escherichia coli UTI89 phosphoglyceromutase YP_543116.2 4046975 D 364106 CDS YP_543117.1 91213131 3989619 4048529..4049812 1 NC_007946.1 hypothetical protein 4049812 yibP 3989619 yibP Escherichia coli UTI89 hypothetical protein YP_543117.1 4048529 D 364106 CDS YP_543118.1 91213132 3989620 4049816..4050775 1 NC_007946.1 hypothetical protein 4050775 yibQ 3989620 yibQ Escherichia coli UTI89 hypothetical protein YP_543118.1 4049816 D 364106 CDS YP_543119.1 91213133 3989621 complement(4050762..4051796) 1 NC_007946.1 glycosyl transferase 4051796 yibD 3989621 yibD Escherichia coli UTI89 glycosyl transferase YP_543119.1 4050762 R 364106 CDS YP_543120.1 91213134 3989622 4052026..4053051 1 NC_007946.1 hypothetical protein 4053051 3989622 UTI89_C4161 Escherichia coli UTI89 hypothetical protein YP_543120.1 4052026 D 364106 CDS YP_543121.1 91213135 3989623 complement(4052035..4053060) 1 NC_007946.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4053060 tdh 3989623 tdh Escherichia coli UTI89 L-threonine 3-dehydrogenase YP_543121.1 4052035 R 364106 CDS YP_543122.1 91213136 3989624 complement(4053070..4054266) 1 NC_007946.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 4054266 kbl 3989624 kbl Escherichia coli UTI89 2-amino-3-ketobutyrate CoA ligase YP_543122.1 4053070 R 364106 CDS YP_543123.1 91213137 3989625 4054480..4055412 1 NC_007946.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4055412 rfaD 3989625 rfaD Escherichia coli UTI89 ADP-L-glycero-D-manno-heptose-6-epimerase YP_543123.1 4054480 D 364106 CDS YP_543124.1 91213138 3991051 4055422..4056468 1 NC_007946.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4056468 rfaF 3991051 rfaF Escherichia coli UTI89 ADP-heptose:LPS heptosyltransferase II YP_543124.1 4055422 D 364106 CDS YP_543125.1 91213139 3991052 4056472..4057452 1 NC_007946.1 synonym: b3621, rfa-2, rfa2, waaC, yibC; ADP-heptose:LPS heptosyl transferase I 4057452 rfaC 3991052 rfaC Escherichia coli UTI89 ADP-heptose:LPS heptosyl transferase I YP_543125.1 4056472 D 364106 CDS YP_543126.1 91213140 3991053 complement(4057522..4058775) 1 NC_007946.1 lipid A-core surface polymer ligase 4058775 waaL 3991053 waaL Escherichia coli UTI89 lipid A-core surface polymer ligase YP_543126.1 4057522 R 364106 CDS YP_543127.1 91213141 3991054 complement(4058821..4059804) 1 NC_007946.1 beta1,3-glucosyltransferase 4059804 waaV 3991054 waaV Escherichia coli UTI89 beta1,3-glucosyltransferase YP_543127.1 4058821 R 364106 CDS YP_543128.1 91213142 3991055 complement(4059886..4060914) 1 NC_007946.1 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase 4060914 waaW 3991055 waaW Escherichia coli UTI89 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase YP_543128.1 4059886 R 364106 CDS YP_543129.1 91213143 3991056 complement(4060940..4061632) 1 NC_007946.1 synonym: b3625, waaY; lipopolysaccharide core biosynthesis protein 4061632 rfaY 3991056 rfaY Escherichia coli UTI89 lipopolysaccharide core biosynthesis protein YP_543129.1 4060940 R 364106 CDS YP_543130.1 91213144 3991057 complement(4061642..4062637) 1 NC_007946.1 synonym: b3626, waaJ, waaR; lipopolysaccharide 1,2-glucosyltransferase 4062637 rfaJ 3991057 rfaJ Escherichia coli UTI89 lipopolysaccharide 1,2-glucosyltransferase YP_543130.1 4061642 R 364106 CDS YP_543131.1 91213145 3991058 complement(4062654..4063670) 1 NC_007946.1 synonym: b3627, waaI, waaO; lipopolysaccharide 1,3-galactosyltransferase 4063670 rafI 3991058 rafI Escherichia coli UTI89 lipopolysaccharide 1,3-galactosyltransferase YP_543131.1 4062654 R 364106 CDS YP_543132.1 91213146 3991059 complement(4063686..4064492) 1 NC_007946.1 synonym: b3630, waaP; lipopolysaccharide core biosynthesis protein rfaP 4064492 rfaP 3991059 rfaP Escherichia coli UTI89 lipopolysaccharide core biosynthesis protein rfaP YP_543132.1 4063686 R 364106 CDS YP_543133.1 91213147 3991060 complement(4064476..4065600) 1 NC_007946.1 synonym: b3631, pcsA, waaG; lipopolysaccharide core biosynthesis glucosyltransferase I 4065600 rfaG 3991060 rfaG Escherichia coli UTI89 lipopolysaccharide core biosynthesis glucosyltransferase I YP_543133.1 4064476 R 364106 CDS YP_543134.1 91213148 3991061 complement(4065597..4066655) 1 NC_007946.1 lipopolysaccharide core biosynthesis protein 4066655 rfaQ 3991061 rfaQ Escherichia coli UTI89 lipopolysaccharide core biosynthesis protein YP_543134.1 4065597 R 364106 CDS YP_543135.1 91213149 3991062 4067068..4068345 1 NC_007946.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4068345 kdtA 3991062 kdtA Escherichia coli UTI89 3-deoxy-D-manno-octulosonic-acid transferase YP_543135.1 4067068 D 364106 CDS YP_543136.1 91213150 3991063 4068353..4068832 1 NC_007946.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4068832 coaD 3991063 coaD Escherichia coli UTI89 phosphopantetheine adenylyltransferase YP_543136.1 4068353 D 364106 CDS YP_543137.1 91213151 3991064 complement(4068871..4069680) 1 NC_007946.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4069680 mutM 3991064 mutM Escherichia coli UTI89 formamidopyrimidine-DNA glycosylase YP_543137.1 4068871 R 364106 CDS YP_543138.1 91213152 3991065 4069694..4069969 1 NC_007946.1 hypothetical protein 4069969 3991065 UTI89_C4179 Escherichia coli UTI89 hypothetical protein YP_543138.1 4069694 D 364106 CDS YP_543139.1 91213153 3991066 complement(4069778..4069945) 1 NC_007946.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4069945 rpmG 3991066 rpmG Escherichia coli UTI89 50S ribosomal protein L33 YP_543139.1 4069778 R 364106 CDS YP_543140.1 91213154 3991067 complement(4069966..4070202) 1 NC_007946.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4070202 rpmB 3991067 rpmB Escherichia coli UTI89 50S ribosomal protein L28 YP_543140.1 4069966 R 364106 CDS YP_543141.1 91213155 3991068 complement(4070419..4071093) 1 NC_007946.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4071093 radC 3991068 radC Escherichia coli UTI89 DNA repair protein RadC YP_543141.1 4070419 R 364106 CDS YP_543142.1 91213156 3991069 4071187..4072479 1 NC_007946.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4072479 dfp 3991069 dfp Escherichia coli UTI89 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_543142.1 4071187 D 364106 CDS YP_543143.1 91213157 3991318 4072457..4072915 1 NC_007946.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4072915 dut 3991318 dut Escherichia coli UTI89 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_543143.1 4072457 D 364106 CDS YP_543144.2 162138340 3991319 4073022..4073618 1 NC_007946.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4073618 slmA 3991319 slmA Escherichia coli UTI89 nucleoid occlusion protein YP_543144.2 4073022 D 364106 CDS YP_543145.2 162138339 3991320 complement(4073655..4074296) 1 NC_007946.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4074296 pyrE 3991320 pyrE Escherichia coli UTI89 orotate phosphoribosyltransferase YP_543145.2 4073655 R 364106 CDS YP_543146.2 162138338 3991321 complement(4074362..4075078) 1 NC_007946.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4075078 rph 3991321 rph Escherichia coli UTI89 ribonuclease PH YP_543146.2 4074362 R 364106 CDS YP_543147.1 91213161 3991322 4075205..4076068 1 NC_007946.1 hypothetical protein 4076068 yicC 3991322 yicC Escherichia coli UTI89 hypothetical protein YP_543147.1 4075205 D 364106 CDS YP_543148.2 162138337 3991323 4076290..4077114 1 NC_007946.1 DNA-damage-inducible protein D 4077114 dinD 3991323 dinD Escherichia coli UTI89 DNA-damage-inducible protein D YP_543148.2 4076290 D 364106 CDS YP_543149.1 91213163 3991324 4077352..4078023 1 NC_007946.1 hypothetical protein 4078023 yicG 3991324 yicG Escherichia coli UTI89 hypothetical protein YP_543149.1 4077352 D 364106 CDS YP_543150.1 91213164 3991325 complement(4078020..4079708) 1 NC_007946.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4079708 ligB 3991325 ligB Escherichia coli UTI89 NAD-dependent DNA ligase LigB YP_543150.1 4078020 R 364106 CDS YP_543151.1 91213165 3991326 complement(4079563..4079826) 1 NC_007946.1 hypothetical protein 4079826 3991326 UTI89_C4192 Escherichia coli UTI89 hypothetical protein YP_543151.1 4079563 R 364106 CDS YP_543152.1 91213166 3991327 4079903..4080583 1 NC_007946.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4080583 gmk 3991327 gmk Escherichia coli UTI89 guanylate kinase YP_543152.1 4079903 D 364106 CDS YP_543153.1 91213167 3991328 4080638..4080913 1 NC_007946.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4080913 rpoZ 3991328 rpoZ Escherichia coli UTI89 DNA-directed RNA polymerase subunit omega YP_543153.1 4080638 D 364106 CDS YP_543154.1 91213168 3991329 4080932..4083040 1 NC_007946.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4083040 spoT 3991329 spoT Escherichia coli UTI89 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_543154.1 4080932 D 364106 CDS YP_543155.1 91213169 3991330 4083047..4083736 1 NC_007946.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4083736 spoU 3991330 spoU Escherichia coli UTI89 tRNA guanosine-2'-O-methyltransferase YP_543155.1 4083047 D 364106 CDS YP_543156.2 162138336 3991331 4083742..4085823 1 NC_007946.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4085823 recG 3991331 recG Escherichia coli UTI89 ATP-dependent DNA helicase RecG YP_543156.2 4083742 D 364106 CDS YP_543157.1 91213171 3991332 complement(4085857..4087062) 1 NC_007946.1 glutamate transport protein 4087062 3991332 UTI89_C4198 Escherichia coli UTI89 glutamate transport protein YP_543157.1 4085857 R 364106 CDS YP_543158.1 91213172 3991333 4087333..4088733 1 NC_007946.1 transport protein 4088733 yicE 3991333 yicE Escherichia coli UTI89 transport protein YP_543158.1 4087333 D 364106 CDS YP_543159.1 91213173 3991334 4088830..4090563 1 NC_007946.1 hypothetical protein 4090563 yicH 3991334 yicH Escherichia coli UTI89 hypothetical protein YP_543159.1 4088830 D 364106 CDS YP_543160.1 91213174 3991335 complement(4090607..4091326) 1 NC_007946.1 hypothetical protein 4091326 3991335 UTI89_C4201 Escherichia coli UTI89 hypothetical protein YP_543160.1 4090607 R 364106 CDS YP_543161.1 91213175 3991336 complement(4091268..4092233) 1 NC_007946.1 hypothetical protein 4092233 3991336 UTI89_C4202 Escherichia coli UTI89 hypothetical protein YP_543161.1 4091268 R 364106 CDS YP_543162.1 91213176 3991337 complement(4092248..4093108) 1 NC_007946.1 hypothetical protein 4093108 3991337 UTI89_C4203 Escherichia coli UTI89 hypothetical protein YP_543162.1 4092248 R 364106 CDS YP_543163.1 91213177 3991481 complement(4093189..4094040) 1 NC_007946.1 aldolase 4094040 3991481 UTI89_C4204 Escherichia coli UTI89 aldolase YP_543163.1 4093189 R 364106 CDS YP_543164.1 91213178 3991482 complement(4094052..4095143) 1 NC_007946.1 PTS enzyme-II fructose 4095143 3991482 UTI89_C4205 Escherichia coli UTI89 PTS enzyme-II fructose YP_543164.1 4094052 R 364106 CDS YP_543165.1 91213179 3991483 complement(4095168..4095482) 1 NC_007946.1 PTS system fructose-like transporter subunit IIB 4095482 3991483 UTI89_C4206 Escherichia coli UTI89 PTS system fructose-like transporter subunit IIB YP_543165.1 4095168 R 364106 CDS YP_543166.1 91213180 3991484 complement(4095500..4095970) 1 NC_007946.1 phosphotransferase system (PTS), fructose-specific 4095970 3991484 UTI89_C4207 Escherichia coli UTI89 phosphotransferase system (PTS), fructose-specific YP_543166.1 4095500 R 364106 CDS YP_543167.1 91213181 3991485 complement(4095997..4097550) 1 NC_007946.1 transcriptional antiterminator 4097550 3991485 UTI89_C4208 Escherichia coli UTI89 transcriptional antiterminator YP_543167.1 4095997 R 364106 CDS YP_543168.1 91213182 3991486 complement(4097845..4100163) 1 NC_007946.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 4100163 yicI 3991486 yicI Escherichia coli UTI89 alpha-xylosidase YicI YP_543168.1 4097845 R 364106 CDS YP_543169.2 162138335 3991487 complement(4100173..4101555) 1 NC_007946.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4101555 yicJ 3991487 yicJ Escherichia coli UTI89 transporter YP_543169.2 4100173 R 364106 CDS YP_543170.1 91213184 3991489 4101995..4103032 1 NC_007946.1 cytoplasmic protein 4103032 rhuM 3991489 rhuM Escherichia coli UTI89 cytoplasmic protein YP_543170.1 4101995 D 364106 CDS YP_543171.1 91213185 3991490 4103240..4103461 1 NC_007946.1 hypothetical protein 4103461 3991490 UTI89_C4213 Escherichia coli UTI89 hypothetical protein YP_543171.1 4103240 D 364106 CDS YP_543172.1 91213186 3991491 4104213..4105190 1 NC_007946.1 transport protein YicL 4105190 yicL 3991491 yicL Escherichia coli UTI89 transport protein YicL YP_543172.1 4104213 D 364106 CDS YP_543173.1 91213187 3991492 complement(4105194..4106012) 1 NC_007946.1 cytoplasmic membrane lipoprotein-28 4106012 nlpA 3991492 nlpA Escherichia coli UTI89 cytoplasmic membrane lipoprotein-28 YP_543173.1 4105194 R 364106 CDS YP_543174.1 91213188 3991493 complement(4106009..4106152) 1 NC_007946.1 hypothetical protein 4106152 3991493 UTI89_C4216 Escherichia coli UTI89 hypothetical protein YP_543174.1 4106009 R 364106 CDS YP_543175.1 91213189 3991494 4106165..4106527 1 NC_007946.1 hypothetical protein 4106527 3991494 UTI89_C4217 Escherichia coli UTI89 hypothetical protein YP_543175.1 4106165 D 364106 CDS YP_543176.2 162138334 3991495 complement(4106568..4107758) 1 NC_007946.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4107758 nepI 3991495 nepI Escherichia coli UTI89 ribonucleoside transporter YP_543176.2 4106568 R 364106 CDS YP_543177.1 91213191 3991496 complement(4107969..4108448) 1 NC_007946.1 hypothetical protein 4108448 yicN 3991496 yicN Escherichia coli UTI89 hypothetical protein YP_543177.1 4107969 R 364106 CDS YP_543178.1 91213192 3991497 complement(4108474..4109886) 1 NC_007946.1 hypothetical protein 4109886 yicO 3991497 yicO Escherichia coli UTI89 hypothetical protein YP_543178.1 4108474 R 364106 CDS YP_543179.1 91213193 3991498 4109983..4111749 1 NC_007946.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4111749 yicP 3991498 yicP Escherichia coli UTI89 cryptic adenine deaminase YP_543179.1 4109983 D 364106 CDS YP_543180.1 91213194 3989920 complement(4111796..4113187) 1 NC_007946.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4113187 uhpT 3989920 uhpT Escherichia coli UTI89 sugar phosphate antiporter YP_543180.1 4111796 R 364106 CDS YP_543181.1 91213195 3989921 complement(4113325..4114647) 1 NC_007946.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4114647 uhpC 3989921 uhpC Escherichia coli UTI89 regulatory protein UhpC YP_543181.1 4113325 R 364106 CDS YP_543182.1 91213196 3989922 complement(4114654..4116156) 1 NC_007946.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4116156 uhpB 3989922 uhpB Escherichia coli UTI89 sensory histidine kinase UhpB YP_543182.1 4114654 R 364106 CDS YP_543183.1 91213197 3989923 complement(4116156..4116746) 1 NC_007946.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4116746 uhpA 3989923 uhpA Escherichia coli UTI89 DNA-binding transcriptional activator UhpA YP_543183.1 4116156 R 364106 CDS YP_543184.1 91213198 3989924 complement(4116819..4117109) 1 NC_007946.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4117109 ilvN 3989924 ilvN Escherichia coli UTI89 acetolactate synthase 1 regulatory subunit YP_543184.1 4116819 R 364106 CDS YP_543185.1 91213199 3989925 complement(4117113..4118801) 1 NC_007946.1 acetolactate synthase catalytic subunit 4118801 ilvB 3989925 ilvB Escherichia coli UTI89 acetolactate synthase catalytic subunit YP_543185.1 4117113 R 364106 CDS YP_543186.1 91213200 3989926 4118785..4119117 1 NC_007946.1 hypothetical protein 4119117 3989926 UTI89_C4228 Escherichia coli UTI89 hypothetical protein YP_543186.1 4118785 D 364106 CDS YP_543187.1 91213201 3989927 4119400..4120590 1 NC_007946.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4120590 emrD 3989927 emrD Escherichia coli UTI89 multidrug resistance protein D YP_543187.1 4119400 D 364106 CDS YP_543188.1 91213202 3989928 complement(4120598..4121095) 1 NC_007946.1 hypothetical protein 4121095 yidF 3989928 yidF Escherichia coli UTI89 hypothetical protein YP_543188.1 4120598 R 364106 CDS YP_543189.1 91213203 3989929 complement(4121092..4121454) 1 NC_007946.1 hypothetical protein 4121454 yidG 3989929 yidG Escherichia coli UTI89 hypothetical protein YP_543189.1 4121092 R 364106 CDS YP_543190.1 91213204 3989930 complement(4121444..4121851) 1 NC_007946.1 hypothetical protein 4121851 yidH 3989930 yidH Escherichia coli UTI89 hypothetical protein YP_543190.1 4121444 R 364106 CDS YP_543191.1 91213205 3989931 complement(4123340..4125055) 1 NC_007946.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4125055 yidK 3989931 yidK Escherichia coli UTI89 symporter YidK YP_543191.1 4123340 R 364106 CDS YP_543192.1 91213206 3989932 4125192..4126088 1 NC_007946.1 transcriptional regulator YidL 4126088 yidL 3989932 yidL Escherichia coli UTI89 transcriptional regulator YidL YP_543192.1 4125192 D 364106 CDS YP_543193.1 91213207 3989933 complement(4126178..4127863) 1 NC_007946.1 hypothetical protein 4127863 yidE 3989933 yidE Escherichia coli UTI89 hypothetical protein YP_543193.1 4126178 R 364106 CDS YP_543194.1 91213208 3989934 4127869..4128039 1 NC_007946.1 hypothetical protein 4128039 3989934 UTI89_C4236 Escherichia coli UTI89 hypothetical protein YP_543194.1 4127869 D 364106 CDS YP_543195.2 162138333 3989935 complement(4128036..4128464) 1 NC_007946.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4128464 ibpB 3989935 ibpB Escherichia coli UTI89 heat shock chaperone IbpB YP_543195.2 4128036 R 364106 CDS YP_543196.1 91213210 3989936 complement(4128576..4128995) 1 NC_007946.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4128995 ibpA 3989936 ibpA Escherichia coli UTI89 heat shock protein IbpA YP_543196.1 4128576 R 364106 CDS YP_543197.2 162138332 3989937 4129295..4129627 1 NC_007946.1 hypothetical protein 4129627 yidQ 3989937 yidQ Escherichia coli UTI89 hypothetical protein YP_543197.2 4129295 D 364106 CDS YP_543198.1 91213212 3989938 complement(4129631..4130881) 1 NC_007946.1 hypothetical protein 4130881 yidR 3989938 yidR Escherichia coli UTI89 hypothetical protein YP_543198.1 4129631 R 364106 CDS YP_543199.2 162138331 3989939 4130946..4132046 1 NC_007946.1 FAD/NAD(P)-binding domain; oxidoreductase 4132046 yidS 3989939 yidS Escherichia coli UTI89 oxidoreductase YP_543199.2 4130946 D 364106 CDS YP_543200.1 91213214 3992796 complement(4132007..4133344) 1 NC_007946.1 D-galactonate transporter 4133344 dgoT 3992796 dgoT Escherichia coli UTI89 D-galactonate transporter YP_543200.1 4132007 R 364106 CDS YP_543201.1 91213215 3992797 complement(4133419..4134567) 1 NC_007946.1 galactonate dehydratase 4134567 dgoA 3992797 dgoA Escherichia coli UTI89 galactonate dehydratase YP_543201.1 4133419 R 364106 CDS YP_543202.1 91213216 3992798 complement(4134564..4135181) 1 NC_007946.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4135181 3992798 UTI89_C4244 Escherichia coli UTI89 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_543202.1 4134564 R 364106 CDS YP_543203.1 91213217 3992799 complement(4135165..4136043) 1 NC_007946.1 2-dehydro-3-deoxygalactonokinase 4136043 dgoK 3992799 dgoK Escherichia coli UTI89 2-dehydro-3-deoxygalactonokinase YP_543203.1 4135165 R 364106 CDS YP_543204.1 91213218 3992800 complement(4136040..4136729) 1 NC_007946.1 galactonate operon transcriptional repressor 4136729 dgoR 3992800 dgoR Escherichia coli UTI89 galactonate operon transcriptional repressor YP_543204.1 4136040 R 364106 CDS YP_543205.1 91213219 3992801 complement(4137708..4138520) 1 NC_007946.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4138520 yidA 3992801 yidA Escherichia coli UTI89 sugar phosphatase YP_543205.1 4137708 R 364106 CDS YP_543206.1 91213220 3992802 complement(4138635..4139042) 1 NC_007946.1 hypothetical protein 4139042 yidB 3992802 yidB Escherichia coli UTI89 hypothetical protein YP_543206.1 4138635 R 364106 CDS YP_543207.1 91213221 3992803 complement(4139273..4141690) 1 NC_007946.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4141690 gyrB 3992803 gyrB Escherichia coli UTI89 DNA gyrase subunit B YP_543207.1 4139273 R 364106 CDS YP_543208.1 91213222 3992804 complement(4141716..4142789) 1 NC_007946.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4142789 recF 3992804 recF Escherichia coli UTI89 recombination protein F YP_543208.1 4141716 R 364106 CDS YP_543209.1 91213223 3992805 complement(4142789..4143889) 1 NC_007946.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4143889 dnaN 3992805 dnaN Escherichia coli UTI89 DNA polymerase III subunit beta YP_543209.1 4142789 R 364106 CDS YP_543210.1 91213224 3992806 complement(4143894..4145297) 1 NC_007946.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 4145297 dnaA 3992806 dnaA Escherichia coli UTI89 chromosome replication initiator DnaA YP_543210.1 4143894 R 364106 CDS YP_543211.1 91213225 3992807 complement(4145591..4145791) 1 NC_007946.1 hypothetical protein 4145791 3992807 UTI89_C4253 Escherichia coli UTI89 hypothetical protein YP_543211.1 4145591 R 364106 CDS YP_543212.1 91213226 3992808 4145904..4146044 1 NC_007946.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4146044 rpmH 3992808 rpmH Escherichia coli UTI89 50S ribosomal protein L34 YP_543212.1 4145904 D 364106 CDS YP_543213.1 91213227 3992809 4146061..4146420 1 NC_007946.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4146420 rnpA 3992809 rnpA Escherichia coli UTI89 ribonuclease P YP_543213.1 4146061 D 364106 CDS YP_543214.1 91213228 3992810 complement(4146108..4146443) 1 NC_007946.1 hypothetical protein 4146443 3992810 UTI89_C4256 Escherichia coli UTI89 hypothetical protein YP_543214.1 4146108 R 364106 CDS YP_543215.1 91213229 3992811 4146384..4146641 1 NC_007946.1 hypothetical protein 4146641 yidD 3992811 yidD Escherichia coli UTI89 hypothetical protein YP_543215.1 4146384 D 364106 CDS YP_543216.1 91213230 3992812 4146644..4148290 1 NC_007946.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4148290 yidC 3992812 yidC Escherichia coli UTI89 inner membrane protein translocase component YidC YP_543216.1 4146644 D 364106 CDS YP_543217.1 91213231 3992813 4148396..4149760 1 NC_007946.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4149760 trmE 3992813 trmE Escherichia coli UTI89 tRNA modification GTPase TrmE YP_543217.1 4148396 D 364106 CDS YP_543218.1 91213232 3992814 4150002..4150076 1 NC_007946.1 tryptophanase 4150076 tnaL 3992814 tnaL Escherichia coli UTI89 tryptophanase YP_543218.1 4150002 D 364106 CDS YP_543219.1 91213233 3994607 4150282..4151712 1 NC_007946.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4151712 tnaA 3994607 tnaA Escherichia coli UTI89 tryptophanase YP_543219.1 4150282 D 364106 CDS YP_543220.1 91213234 3994608 4151804..4153051 1 NC_007946.1 tryptophan transporter of low affinity; tryptophan permease 4153051 tnaB 3994608 tnaB Escherichia coli UTI89 tryptophan permease YP_543220.1 4151804 D 364106 CDS YP_543221.1 91213235 3994609 4153183..4154358 1 NC_007946.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4154358 yidY 3994609 yidY Escherichia coli UTI89 multidrug efflux system protein MdtL YP_543221.1 4153183 D 364106 CDS YP_543222.1 91213236 3994610 4154324..4155292 1 NC_007946.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4155292 yidZ 3994610 yidZ Escherichia coli UTI89 DNA-binding transcriptional regulator YidZ YP_543222.1 4154324 D 364106 CDS YP_543223.1 91213237 3994611 4155437..4156198 1 NC_007946.1 hypothetical protein 4156198 yieE 3994611 yieE Escherichia coli UTI89 hypothetical protein YP_543223.1 4155437 D 364106 CDS YP_543224.1 91213238 3994612 4156220..4156786 1 NC_007946.1 hypothetical protein 4156786 yieF 3994612 yieF Escherichia coli UTI89 hypothetical protein YP_543224.1 4156220 D 364106 CDS YP_543225.1 91213239 3994613 complement(4156839..4158176) 1 NC_007946.1 membrane/transport protein 4158176 yieG 3994613 yieG Escherichia coli UTI89 membrane/transport protein YP_543225.1 4156839 R 364106 CDS YP_543226.1 91213240 3994614 4159080..4159553 1 NC_007946.1 might be involved in hypersensitivity to nitrofurzone; hypothetical protein 4159553 yieI 3994614 yieI Escherichia coli UTI89 hypothetical protein YP_543226.1 4159080 D 364106 CDS YP_543227.1 91213241 3994615 complement(4159635..4160357) 1 NC_007946.1 6-phosphogluconolactonase 4160357 yieK 3994615 yieK Escherichia coli UTI89 6-phosphogluconolactonase YP_543227.1 4159635 R 364106 CDS YP_543228.1 91213242 3994616 complement(4160372..4161574) 1 NC_007946.1 xylanase 4161574 yieL 3994616 yieL Escherichia coli UTI89 xylanase YP_543228.1 4160372 R 364106 CDS YP_543229.1 91213243 3994617 complement(4161568..4163184) 1 NC_007946.1 outer membrane protein YieC 4163184 yieC 3994617 yieC Escherichia coli UTI89 outer membrane protein YieC YP_543229.1 4161568 R 364106 CDS YP_543230.1 91213244 3994618 complement(4163270..4164664) 1 NC_007946.1 6-phospho-beta-glucosidase 4164664 bglB 3994618 bglB Escherichia coli UTI89 6-phospho-beta-glucosidase YP_543230.1 4163270 R 364106 CDS YP_543231.1 91213245 3994619 complement(4164683..4166632) 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunits IIABC 4166632 bglF 3994619 bglF Escherichia coli UTI89 PTS system beta-glucoside-specific transporter subunits IIABC YP_543231.1 4164683 R 364106 CDS YP_543232.1 91213246 3994620 complement(4166691..4167551) 1 NC_007946.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4167551 bglG 3994620 bglG Escherichia coli UTI89 transcriptional antiterminator BglG YP_543232.1 4166691 R 364106 CDS YP_543233.1 91213247 3994621 4167593..4167715 1 NC_007946.1 hypothetical protein 4167715 3994621 UTI89_C4275 Escherichia coli UTI89 hypothetical protein YP_543233.1 4167593 D 364106 CDS YP_543234.2 162138330 3994622 complement(4167813..4168538) 1 NC_007946.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4168538 phoU 3994622 phoU Escherichia coli UTI89 transcriptional regulator PhoU YP_543234.2 4167813 R 364106 CDS YP_543235.1 91213249 3994623 complement(4168553..4169326) 1 NC_007946.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4169326 pstB 3994623 pstB Escherichia coli UTI89 phosphate transporter ATP-binding protein YP_543235.1 4168553 R 364106 CDS YP_543236.1 91213250 3994624 complement(4169417..4170307) 1 NC_007946.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4170307 pstA 3994624 pstA Escherichia coli UTI89 phosphate transporter permease subunit PtsA YP_543236.1 4169417 R 364106 CDS YP_543237.1 91213251 3994625 complement(4170307..4171266) 1 NC_007946.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4171266 pstC 3994625 pstC Escherichia coli UTI89 phosphate transporter permease subunit PstC YP_543237.1 4170307 R 364106 CDS YP_543238.1 91213252 3994626 complement(4171353..4172393) 1 NC_007946.1 phosphate ABC transporter periplasmic substrate-binding protein PstS 4172393 pstS 3994626 pstS Escherichia coli UTI89 phosphate ABC transporter periplasmic substrate-binding protein PstS YP_543238.1 4171353 R 364106 CDS YP_543239.1 91213253 3994403 complement(4172707..4174536) 1 NC_007946.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4174536 glmS 3994403 glmS Escherichia coli UTI89 glucosamine--fructose-6-phosphate aminotransferase YP_543239.1 4172707 R 364106 CDS YP_543240.1 91213254 3994404 complement(4174697..4176067) 1 NC_007946.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4176067 glmU 3994404 glmU Escherichia coli UTI89 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_543240.1 4174697 R 364106 CDS YP_543241.1 91213255 3994405 4176337..4176864 1 NC_007946.1 hypothetical protein 4176864 3994405 UTI89_C4283 Escherichia coli UTI89 hypothetical protein YP_543241.1 4176337 D 364106 CDS YP_543242.1 91213256 3994406 complement(4176421..4176840) 1 NC_007946.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 4176840 atpC 3994406 atpC Escherichia coli UTI89 ATP synthase F0F1 subunit epsilon YP_543242.1 4176421 R 364106 CDS YP_543243.1 91213257 3994407 complement(4176861..4178243) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 4178243 atpD 3994407 atpD Escherichia coli UTI89 ATP synthase F0F1 subunit beta YP_543243.1 4176861 R 364106 CDS YP_543244.1 91213258 3994408 complement(4178270..4179133) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 4179133 atpG 3994408 atpG Escherichia coli UTI89 ATP synthase F0F1 subunit gamma YP_543244.1 4178270 R 364106 CDS YP_543245.1 91213259 3994409 complement(4179184..4180725) 1 NC_007946.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 4180725 atpA 3994409 atpA Escherichia coli UTI89 ATP synthase F0F1 subunit alpha YP_543245.1 4179184 R 364106 CDS YP_543246.1 91213260 3994410 4179193..4180872 1 NC_007946.1 hypothetical protein 4180872 3994410 UTI89_C4288 Escherichia coli UTI89 hypothetical protein YP_543246.1 4179193 D 364106 CDS YP_543247.1 91213261 3994411 complement(4180738..4181271) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4181271 atpH 3994411 atpH Escherichia coli UTI89 ATP synthase F0F1 subunit delta YP_543247.1 4180738 R 364106 CDS YP_543248.1 91213262 3994412 4180912..4181649 1 NC_007946.1 hypothetical protein 4181649 3994412 UTI89_C4290 Escherichia coli UTI89 hypothetical protein YP_543248.1 4180912 D 364106 CDS YP_543249.1 91213263 3994413 complement(4181286..4181756) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 4181756 atpF 3994413 atpF Escherichia coli UTI89 ATP synthase F0F1 subunit B YP_543249.1 4181286 R 364106 CDS YP_543250.1 91213264 3994414 complement(4181818..4182057) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4182057 atpE 3994414 atpE Escherichia coli UTI89 ATP synthase F0F1 subunit C YP_543250.1 4181818 R 364106 CDS YP_543251.1 91213265 3994415 complement(4182104..4182919) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4182919 atpB 3994415 atpB Escherichia coli UTI89 ATP synthase F0F1 subunit A YP_543251.1 4182104 R 364106 CDS YP_543252.1 91213266 3994416 complement(4182928..4183320) 1 NC_007946.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4183320 atpI 3994416 atpI Escherichia coli UTI89 F0F1 ATP synthase subunit I YP_543252.1 4182928 R 364106 CDS YP_543253.1 91213267 3994417 complement(4183925..4184548) 1 NC_007946.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4184548 gidB 3994417 gidB Escherichia coli UTI89 16S rRNA methyltransferase GidB YP_543253.1 4183925 R 364106 CDS YP_543254.1 91213268 3994418 complement(4184612..4186501) 1 NC_007946.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4186501 gidA 3994418 gidA Escherichia coli UTI89 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_543254.1 4184612 R 364106 CDS YP_543255.1 91213269 3994419 complement(4186880..4187323) 1 NC_007946.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4187323 mioC 3994419 mioC Escherichia coli UTI89 flavodoxin YP_543255.1 4186880 R 364106 CDS YP_543256.1 91213270 3994420 complement(4187413..4187871) 1 NC_007946.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4187871 asnC 3994420 asnC Escherichia coli UTI89 DNA-binding transcriptional regulator AsnC YP_543256.1 4187413 R 364106 CDS YP_543257.1 91213271 3994421 4188023..4189015 1 NC_007946.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4189015 asnA 3994421 asnA Escherichia coli UTI89 asparagine synthetase AsnA YP_543257.1 4188023 D 364106 CDS YP_543258.1 91213272 3994312 complement(4189020..4190471) 1 NC_007946.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4190471 yieM 3994312 yieM Escherichia coli UTI89 hypothetical protein YP_543258.1 4189020 R 364106 CDS YP_543259.1 91213273 3994313 complement(4190465..4191985) 1 NC_007946.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4191985 yieN 3994313 yieN Escherichia coli UTI89 regulatory ATPase RavA YP_543259.1 4190465 R 364106 CDS YP_543260.1 91213274 3994314 4192184..4194052 1 NC_007946.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4194052 trkD 3994314 trkD Escherichia coli UTI89 potassium transport protein Kup YP_543260.1 4192184 D 364106 CDS YP_543261.1 91213275 3994315 4194207..4194638 1 NC_007946.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4194638 rbsD 3994315 rbsD Escherichia coli UTI89 D-ribose pyranase YP_543261.1 4194207 D 364106 CDS YP_543262.1 91213276 3994316 4194646..4196151 1 NC_007946.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4196151 rbsA 3994316 rbsA Escherichia coli UTI89 D-ribose transporter ATP binding protein YP_543262.1 4194646 D 364106 CDS YP_543263.1 91213277 3994317 4196156..4197121 1 NC_007946.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4197121 rbsC 3994317 rbsC Escherichia coli UTI89 ribose ABC transporter permease YP_543263.1 4196156 D 364106 CDS YP_543264.1 91213278 3994318 4197140..4198036 1 NC_007946.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4198036 rbsB 3994318 rbsB Escherichia coli UTI89 D-ribose transporter subunit RbsB YP_543264.1 4197140 D 364106 CDS YP_543265.2 162138329 3994319 4198147..4199091 1 NC_007946.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4199091 rbsK 3994319 rbsK Escherichia coli UTI89 ribokinase YP_543265.2 4198147 D 364106 CDS YP_543266.1 91213280 3994320 4199095..4200087 1 NC_007946.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4200087 rbsR 3994320 rbsR Escherichia coli UTI89 transcriptional repressor RbsR YP_543266.1 4199095 D 364106 CDS YP_543267.1 91213281 3994321 complement(4200053..4201480) 1 NC_007946.1 transport protein YieO 4201480 yieO 3994321 yieO Escherichia coli UTI89 transport protein YieO YP_543267.1 4200053 R 364106 CDS YP_543268.1 91213282 3994322 complement(4201503..4202195) 1 NC_007946.1 transcriptional regulator YieP 4202195 yieP 3994322 yieP Escherichia coli UTI89 transcriptional regulator YieP YP_543268.1 4201503 R 364106 CDS YP_543272.1 91213286 3994027 complement(4207996..4208835) 1 NC_007946.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4208835 hdfR 3994027 hdfR Escherichia coli UTI89 transcriptional regulator HdfR YP_543272.1 4207996 R 364106 CDS YP_543273.1 91213287 3994028 4208954..4209292 1 NC_007946.1 hypothetical protein 4209292 yifE 3994028 yifE Escherichia coli UTI89 hypothetical protein YP_543273.1 4208954 D 364106 CDS YP_543274.1 91213288 3994029 complement(4209317..4210867) 1 NC_007946.1 among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 4210867 yifB 3994029 yifB Escherichia coli UTI89 ATP-dependent protease YP_543274.1 4209317 R 364106 CDS YP_543275.1 91213289 3994030 complement(4210858..4211043) 1 NC_007946.1 hypothetical protein 4211043 3994030 UTI89_C4323 Escherichia coli UTI89 hypothetical protein YP_543275.1 4210858 R 364106 CDS YP_543276.1 91213290 3994031 4211428..4213074 1 NC_007946.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4213074 ilvG 3994031 ilvG Escherichia coli UTI89 acetolactate synthase 2 catalytic subunit YP_543276.1 4211428 D 364106 CDS YP_543277.1 91213291 3994032 4213071..4213334 1 NC_007946.1 acetolactate synthase 2 regulatory subunit 4213334 ilvM 3994032 ilvM Escherichia coli UTI89 acetolactate synthase 2 regulatory subunit YP_543277.1 4213071 D 364106 CDS YP_543278.1 91213292 3994033 4213354..4214283 1 NC_007946.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4214283 ilvE 3994033 ilvE Escherichia coli UTI89 branched-chain amino acid aminotransferase YP_543278.1 4213354 D 364106 CDS YP_543279.1 91213293 3994034 4214348..4216198 1 NC_007946.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4216198 ilvD 3994034 ilvD Escherichia coli UTI89 dihydroxy-acid dehydratase YP_543279.1 4214348 D 364106 CDS YP_543280.1 91213294 3994035 4216198..4217745 1 NC_007946.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4217745 ilvA 3994035 ilvA Escherichia coli UTI89 threonine dehydratase YP_543280.1 4216198 D 364106 CDS YP_543281.2 162138328 3994036 complement(4217742..4218632) 1 NC_007946.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4218632 ilvY 3994036 ilvY Escherichia coli UTI89 DNA-binding transcriptional regulator IlvY YP_543281.2 4217742 R 364106 CDS YP_543282.1 91213296 3994037 4218632..4220257 1 NC_007946.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4220257 ilvC 3994037 ilvC Escherichia coli UTI89 ketol-acid reductoisomerase YP_543282.1 4218632 D 364106 CDS YP_543283.1 91213297 3994038 complement(4220303..4220584) 1 NC_007946.1 peptidyl-prolyl cis-trans isomerase C 4220584 ppiC 3994038 ppiC Escherichia coli UTI89 peptidyl-prolyl cis-trans isomerase C YP_543283.1 4220303 R 364106 CDS YP_543284.1 91213298 3994039 4220671..4222692 1 NC_007946.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4222692 rep 3994039 rep Escherichia coli UTI89 ATP-dependent DNA helicase Rep YP_543284.1 4220671 D 364106 CDS YP_543285.1 91213299 3993312 complement(4222739..4224232) 1 NC_007946.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4224232 gppA 3993312 gppA Escherichia coli UTI89 guanosine pentaphosphate phosphohydrolase YP_543285.1 4222739 R 364106 CDS YP_543286.1 91213300 3993313 complement(4224359..4225624) 1 NC_007946.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4225624 rhlB 3993313 rhlB Escherichia coli UTI89 ATP-dependent RNA helicase RhlB YP_543286.1 4224359 R 364106 CDS YP_543287.1 91213301 3993314 4225650..4226084 1 NC_007946.1 thioredoxin 4226084 trxA 3993314 trxA Escherichia coli UTI89 thioredoxin YP_543287.1 4225650 D 364106 CDS YP_543288.1 91213302 3993315 complement(4225749..4226141) 1 NC_007946.1 hypothetical protein 4226141 3993315 UTI89_C4336 Escherichia coli UTI89 hypothetical protein YP_543288.1 4225749 R 364106 CDS YP_543289.1 91213303 3993316 4226225..4226326 1 NC_007946.1 rho operon leader peptide 4226326 rhoL 3993316 rhoL Escherichia coli UTI89 rho operon leader peptide YP_543289.1 4226225 D 364106 CDS YP_543290.1 91213304 3993317 4226339..4227670 1 NC_007946.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4227670 rho 3993317 rho Escherichia coli UTI89 transcription termination factor Rho YP_543290.1 4226339 D 364106 CDS YP_543291.1 91213305 3993318 4227680..4227805 1 NC_007946.1 hypothetical protein 4227805 3993318 UTI89_C4339 Escherichia coli UTI89 hypothetical protein YP_543291.1 4227680 D 364106 CDS YP_543292.1 91213306 3993319 4227910..4229013 1 NC_007946.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyl transferase 4229013 rfe 3993319 rfe Escherichia coli UTI89 undecaprenyl-phosphate alpha-N-acetylglucosaminyl transferase YP_543292.1 4227910 D 364106 CDS YP_543293.1 91213307 3993320 4229022..4230071 1 NC_007946.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4230071 wzzE 3993320 wzzE Escherichia coli UTI89 lipopolysaccharide biosynthesis protein WzzE YP_543293.1 4229022 D 364106 CDS YP_543294.1 91213308 3993321 4230085..4231257 1 NC_007946.1 synonym: yifF, b3786, G7969, nfrC, wecB; UDP-N-acetylglucosamine 2-epimerase 4231257 rffE 3993321 rffE Escherichia coli UTI89 UDP-N-acetylglucosamine 2-epimerase YP_543294.1 4230085 D 364106 CDS YP_543295.1 91213309 3993322 4231254..4232516 1 NC_007946.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4232516 wecC 3993322 wecC Escherichia coli UTI89 UDP-N-acetyl-D-mannosamine dehydrogenase YP_543295.1 4231254 D 364106 CDS YP_543296.1 91213310 3993323 4232516..4233583 1 NC_007946.1 synonym: rff, b3788, nfrC, rffE; dTDP-glucose 4,6-dehydratase 4233583 rffG 3993323 rffG Escherichia coli UTI89 dTDP-glucose 4,6-dehydratase YP_543296.1 4232516 D 364106 CDS YP_543297.1 91213311 3993324 4233602..4234483 1 NC_007946.1 synonym: b3789, yifG; glucose-1-phosphate thymidylyltransferase 4234483 rffH 3993324 rffH Escherichia coli UTI89 glucose-1-phosphate thymidylyltransferase YP_543297.1 4233602 D 364106 CDS YP_543298.1 91213312 3993325 4234461..4235135 1 NC_007946.1 synonym: rff, b3790, wecD, yifH; TDP-fucosamine acetyltransferase 4235135 rffC 3993325 rffC Escherichia coli UTI89 TDP-fucosamine acetyltransferase YP_543298.1 4234461 D 364106 CDS YP_543299.1 91213313 3993326 4235140..4236270 1 NC_007946.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4236270 rffA 3993326 rffA Escherichia coli UTI89 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_543299.1 4235140 D 364106 CDS YP_543300.1 91213314 3993327 complement(4235287..4236321) 1 NC_007946.1 hypothetical protein 4236321 3993327 UTI89_C4348 Escherichia coli UTI89 hypothetical protein YP_543300.1 4235287 R 364106 CDS YP_543301.1 91213315 3993328 4236272..4237522 1 NC_007946.1 cytochrome 4237522 wzxE 3993328 wzxE Escherichia coli UTI89 cytochrome YP_543301.1 4236272 D 364106 CDS YP_543302.1 91213316 3993329 4237519..4238598 1 NC_007946.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4238598 3993329 UTI89_C4350 Escherichia coli UTI89 4-alpha-L-fucosyltransferase YP_543302.1 4237519 D 364106 CDS YP_543303.1 91213317 3993330 4238595..4239947 1 NC_007946.1 enterobacterial common antigen polymerase; common antigen polymerase 4239947 wzyE 3993330 wzyE Escherichia coli UTI89 common antigen polymerase YP_543303.1 4238595 D 364106 CDS YP_543304.1 91213318 3993331 4239950..4240690 1 NC_007946.1 synonym: rff, b3794, wecG; UDP-N-acetyl-D-mannosaminuronic acid transferase 4240690 rffM 3993331 rffM Escherichia coli UTI89 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_543304.1 4239950 D 364106 CDS YP_543305.1 91213319 3992509 4240881..4242266 1 NC_007946.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4242266 yifK 3992509 yifK Escherichia coli UTI89 transport protein YifK YP_543305.1 4240881 D 364106 CDS YP_543306.1 91213320 3992514 4242922..4244187 1 NC_007946.1 arylsulfatase 4244187 aslB 3992514 aslB Escherichia coli UTI89 arylsulfatase YP_543306.1 4242922 D 364106 CDS YP_543307.1 91213321 3992515 complement(4244345..4246000) 1 NC_007946.1 arylsulfatase 4246000 aslA 3992515 aslA Escherichia coli UTI89 arylsulfatase YP_543307.1 4244345 R 364106 CDS YP_543308.1 91213322 3992516 4245897..4246052 1 NC_007946.1 hypothetical protein 4246052 3992516 UTI89_C4360 Escherichia coli UTI89 hypothetical protein YP_543308.1 4245897 D 364106 CDS YP_543309.1 91213323 3992517 complement(4246679..4247875) 1 NC_007946.1 protoheme IX biogenesis protein 4247875 hemY 3992517 hemY Escherichia coli UTI89 protoheme IX biogenesis protein YP_543309.1 4246679 R 364106 CDS YP_543310.1 91213324 3992518 complement(4247878..4249077) 1 NC_007946.1 uroporphyrinogen III C-methyltransferase 4249077 hemX 3992518 hemX Escherichia coli UTI89 uroporphyrinogen III C-methyltransferase YP_543310.1 4247878 R 364106 CDS YP_543311.1 91213325 3992519 complement(4249099..4249839) 1 NC_007946.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4249839 hemD 3992519 hemD Escherichia coli UTI89 uroporphyrinogen-III synthase YP_543311.1 4249099 R 364106 CDS YP_543312.1 91213326 3992520 complement(4249836..4250798) 1 NC_007946.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4250798 hemC 3992520 hemC Escherichia coli UTI89 porphobilinogen deaminase YP_543312.1 4249836 R 364106 CDS YP_543313.1 91213327 3992521 4251164..4253710 1 NC_007946.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4253710 cyaA 3992521 cyaA Escherichia coli UTI89 adenylate cyclase YP_543313.1 4251164 D 364106 CDS YP_543314.1 91213328 3992522 complement(4253750..4254070) 1 NC_007946.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4254070 cyaY 3992522 cyaY Escherichia coli UTI89 frataxin-like protein YP_543314.1 4253750 R 364106 CDS YP_543315.1 91213329 3992523 complement(4254118..4255434) 1 NC_007946.1 hypothetical protein 4255434 3992523 UTI89_C4367 Escherichia coli UTI89 hypothetical protein YP_543315.1 4254118 R 364106 CDS YP_543316.1 91213330 3992581 4255566..4255778 1 NC_007946.1 hypothetical protein 4255778 3992581 UTI89_C4368 Escherichia coli UTI89 hypothetical protein YP_543316.1 4255566 D 364106 CDS YP_543317.1 91213331 3992582 4255789..4256292 1 NC_007946.1 IS1 protein InsB 4256292 insB2 3992582 insB2 Escherichia coli UTI89 IS1 protein InsB YP_543317.1 4255789 D 364106 CDS YP_543318.1 91213332 3992583 complement(4256303..4257706) 1 NC_007946.1 hypothetical protein 4257706 3992583 UTI89_C4370 Escherichia coli UTI89 hypothetical protein YP_543318.1 4256303 R 364106 CDS YP_543319.1 91213333 3992584 4257865..4258068 1 NC_007946.1 lipoprotein 4258068 yifL 3992584 yifL Escherichia coli UTI89 lipoprotein YP_543319.1 4257865 D 364106 CDS YP_543320.1 91213334 3992585 4258102..4258929 1 NC_007946.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4258929 dapF 3992585 dapF Escherichia coli UTI89 diaminopimelate epimerase YP_543320.1 4258102 D 364106 CDS YP_543321.1 91213335 3992586 4258926..4259633 1 NC_007946.1 hypothetical protein 4259633 yigA 3992586 yigA Escherichia coli UTI89 hypothetical protein YP_543321.1 4258926 D 364106 CDS YP_543322.1 91213336 3992587 4259630..4260526 1 NC_007946.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4260526 xerC 3992587 xerC Escherichia coli UTI89 site-specific tyrosine recombinase XerC YP_543322.1 4259630 D 364106 CDS YP_543323.1 91213337 3992588 4260526..4261242 1 NC_007946.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4261242 yigB 3992588 yigB Escherichia coli UTI89 flavin mononucleotide phosphatase YP_543323.1 4260526 D 364106 CDS YP_543324.2 162138327 3992589 4261326..4263488 1 NC_007946.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4263488 uvrD 3992589 uvrD Escherichia coli UTI89 DNA-dependent helicase II YP_543324.2 4261326 D 364106 CDS YP_543325.1 91213339 3992590 complement(4263533..4264435) 1 NC_007946.1 hypothetical protein 4264435 3992590 UTI89_C4377 Escherichia coli UTI89 hypothetical protein YP_543325.1 4263533 R 364106 CDS YP_543326.1 91213340 3992591 complement(4264518..4265282) 1 NC_007946.1 hypothetical protein 4265282 3992591 UTI89_C4378 Escherichia coli UTI89 hypothetical protein YP_543326.1 4264518 R 364106 CDS YP_543327.2 162138326 3992592 4265652..4266602 1 NC_007946.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4266602 corA 3992592 corA Escherichia coli UTI89 magnesium/nickel/cobalt transporter CorA YP_543327.2 4265652 D 364106 CDS YP_543328.1 91213342 3992593 complement(4266638..4267135) 1 NC_007946.1 hypothetical protein 4267135 3992593 UTI89_C4380 Escherichia coli UTI89 hypothetical protein YP_543328.1 4266638 R 364106 CDS YP_543329.1 91213343 3992594 complement(4267132..4267980) 1 NC_007946.1 hypothetical protein 4267980 3992594 UTI89_C4381 Escherichia coli UTI89 hypothetical protein YP_543329.1 4267132 R 364106 CDS YP_543330.1 91213344 3992595 complement(4268291..4269181) 1 NC_007946.1 hypothetical protein 4269181 rarD 3992595 rarD Escherichia coli UTI89 hypothetical protein YP_543330.1 4268291 R 364106 CDS YP_543331.2 162138325 3992596 complement(4269233..4269700) 1 NC_007946.1 hypothetical protein 4269700 yigI 3992596 yigI Escherichia coli UTI89 hypothetical protein YP_543331.2 4269233 R 364106 CDS YP_543332.1 91213346 3992597 4269865..4270734 1 NC_007946.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4270734 pldA 3992597 pldA Escherichia coli UTI89 phospholipase A YP_543332.1 4269865 D 364106 CDS YP_543333.1 91213347 3992598 4270738..4270899 1 NC_007946.1 hypothetical protein 4270899 3992598 UTI89_C4385 Escherichia coli UTI89 hypothetical protein YP_543333.1 4270738 D 364106 CDS YP_543334.1 91213348 3992599 4270853..4272688 1 NC_007946.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4272688 recQ 3992599 recQ Escherichia coli UTI89 ATP-dependent DNA helicase RecQ YP_543334.1 4270853 D 364106 CDS YP_543335.1 91213349 3994647 4272752..4273372 1 NC_007946.1 threonine efflux system 4273372 3994647 UTI89_C4387 Escherichia coli UTI89 threonine efflux system YP_543335.1 4272752 D 364106 CDS YP_543336.1 91213350 3994648 complement(4273433..4274053) 1 NC_007946.1 synonym: b3824, yigK; homoserine/homoserine lactone efflux protein 4274053 rhtB 3994648 rhtB Escherichia coli UTI89 homoserine/homoserine lactone efflux protein YP_543336.1 4273433 R 364106 CDS YP_543337.1 91213351 3994649 4274164..4275186 1 NC_007946.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4275186 pldB 3994649 pldB Escherichia coli UTI89 lysophospholipase L2 YP_543337.1 4274164 D 364106 CDS YP_543338.1 91213352 3994650 4275131..4275994 1 NC_007946.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4275994 3994650 UTI89_C4390 Escherichia coli UTI89 sugar phosphatase YP_543338.1 4275131 D 364106 CDS YP_543339.1 91213353 3994651 4276070..4276969 1 NC_007946.1 hypothetical protein 4276969 yigM 3994651 yigM Escherichia coli UTI89 hypothetical protein YP_543339.1 4276070 D 364106 CDS YP_543340.1 91213354 3994652 complement(4276857..4277810) 1 NC_007946.1 regulator for metE and MetH 4277810 metR 3994652 metR Escherichia coli UTI89 regulator for metE and MetH YP_543340.1 4276857 R 364106 CDS YP_543341.1 91213355 3994653 4277928..4280189 1 NC_007946.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4280189 metE 3994653 metE Escherichia coli UTI89 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_543341.1 4277928 D 364106 CDS YP_543342.1 91213356 3994654 complement(4280196..4280321) 1 NC_007946.1 hypothetical protein 4280321 3994654 UTI89_C4394 Escherichia coli UTI89 hypothetical protein YP_543342.1 4280196 R 364106 CDS YP_543343.1 91213357 3994655 complement(4280358..4280618) 1 NC_007946.1 hypothetical protein 4280618 3994655 UTI89_C4395 Escherichia coli UTI89 hypothetical protein YP_543343.1 4280358 R 364106 CDS YP_543344.1 91213358 3994656 complement(4280678..4280935) 1 NC_007946.1 hypothetical protein 4280935 3994656 UTI89_C4396 Escherichia coli UTI89 hypothetical protein YP_543344.1 4280678 R 364106 CDS YP_543345.1 91213359 3994657 complement(4280932..4281621) 1 NC_007946.1 hypothetical protein 4281621 3994657 UTI89_C4397 Escherichia coli UTI89 hypothetical protein YP_543345.1 4280932 R 364106 CDS YP_543346.1 91213360 3994658 4282538..4283107 1 NC_007946.1 hypothetical protein 4283107 3994658 UTI89_C4398 Escherichia coli UTI89 hypothetical protein YP_543346.1 4282538 D 364106 CDS YP_543347.1 91213361 3994659 4283149..4284657 1 NC_007946.1 PTS system glucose-specific transporter subunit IIBC 4284657 3994659 UTI89_C4399 Escherichia coli UTI89 PTS system glucose-specific transporter subunit IIBC YP_543347.1 4283149 D 364106 CDS YP_543348.1 91213362 3994660 4284708..4286705 1 NC_007946.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4286705 3994660 UTI89_C4400 Escherichia coli UTI89 transketolase YP_543348.1 4284708 D 364106 CDS YP_543349.1 91213363 3994661 complement(4286735..4287580) 1 NC_007946.1 hypothetical protein 4287580 3994661 UTI89_C4401 Escherichia coli UTI89 hypothetical protein YP_543349.1 4286735 R 364106 CDS YP_543350.1 91213364 3994662 complement(4287781..4288686) 1 NC_007946.1 hypothetical protein 4288686 3994662 UTI89_C4402 Escherichia coli UTI89 hypothetical protein YP_543350.1 4287781 R 364106 CDS YP_543351.1 91213365 3994663 complement(4288764..4289987) 1 NC_007946.1 permease 4289987 3994663 UTI89_C4403 Escherichia coli UTI89 permease YP_543351.1 4288764 R 364106 CDS YP_543352.1 91213366 3994664 complement(4290013..4290402) 1 NC_007946.1 hypothetical protein 4290402 3994664 UTI89_C4404 Escherichia coli UTI89 hypothetical protein YP_543352.1 4290013 R 364106 CDS YP_543353.1 91213367 3994665 complement(4290419..4291375) 1 NC_007946.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4291375 3994665 UTI89_C4405 Escherichia coli UTI89 carbamate kinase YP_543353.1 4290419 R 364106 CDS YP_543354.1 91213368 3994666 complement(4291368..4292843) 1 NC_007946.1 hypothetical protein 4292843 3994666 UTI89_C4406 Escherichia coli UTI89 hypothetical protein YP_543354.1 4291368 R 364106 CDS YP_543355.1 91213369 3993351 complement(4292789..4294348) 1 NC_007946.1 hypothetical protein 4294348 3993351 UTI89_C4407 Escherichia coli UTI89 hypothetical protein YP_543355.1 4292789 R 364106 CDS YP_543356.1 91213370 3993352 complement(4294443..4295303) 1 NC_007946.1 hypothetical protein 4295303 3993352 UTI89_C4408 Escherichia coli UTI89 hypothetical protein YP_543356.1 4294443 R 364106 CDS YP_543357.1 91213371 3993353 complement(4295309..4295908) 1 NC_007946.1 hypothetical protein 4295908 3993353 UTI89_C4409 Escherichia coli UTI89 hypothetical protein YP_543357.1 4295309 R 364106 CDS YP_543358.1 91213372 3993354 complement(4296234..4297109) 1 NC_007946.1 carboxymethylenebutenolidase 4297109 3993354 UTI89_C4410 Escherichia coli UTI89 carboxymethylenebutenolidase YP_543358.1 4296234 R 364106 CDS YP_543359.2 162138324 3993355 4297305..4298069 1 NC_007946.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4298069 udp 3993355 udp Escherichia coli UTI89 uridine phosphorylase YP_543359.2 4297305 D 364106 CDS YP_543360.1 91213374 3993356 complement(4298104..4299594) 1 NC_007946.1 hypothetical protein 4299594 3993356 UTI89_C4412 Escherichia coli UTI89 hypothetical protein YP_543360.1 4298104 R 364106 CDS YP_543361.1 91213375 3993357 complement(4299607..4300116) 1 NC_007946.1 hypothetical protein 4300116 3993357 UTI89_C4413 Escherichia coli UTI89 hypothetical protein YP_543361.1 4299607 R 364106 CDS YP_543362.1 91213376 3993358 complement(4300130..4301104) 1 NC_007946.1 hypothetical protein 4301104 3993358 UTI89_C4414 Escherichia coli UTI89 hypothetical protein YP_543362.1 4300130 R 364106 CDS YP_543363.1 91213377 3993359 complement(4301129..4301758) 1 NC_007946.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4301758 3993359 UTI89_C4415 Escherichia coli UTI89 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_543363.1 4301129 R 364106 CDS YP_543364.1 91213378 3993360 complement(4301748..4302752) 1 NC_007946.1 hypothetical protein 4302752 3993360 UTI89_C4416 Escherichia coli UTI89 hypothetical protein YP_543364.1 4301748 R 364106 CDS YP_543365.1 91213379 3993361 complement(4302776..4303630) 1 NC_007946.1 transcriptional regulator 4303630 3993361 UTI89_C4417 Escherichia coli UTI89 transcriptional regulator YP_543365.1 4302776 R 364106 CDS YP_543366.1 91213380 3993362 4303707..4303865 1 NC_007946.1 hypothetical protein 4303865 3993362 UTI89_C4418 Escherichia coli UTI89 hypothetical protein YP_543366.1 4303707 D 364106 CDS YP_543367.1 91213381 3993363 4303760..4305187 1 NC_007946.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4305187 rmuC 3993363 rmuC Escherichia coli UTI89 DNA recombination protein RmuC YP_543367.1 4303760 D 364106 CDS YP_543368.1 91213382 3993364 4305282..4306037 1 NC_007946.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4306037 ubiE 3993364 ubiE Escherichia coli UTI89 ubiquinone/menaquinone biosynthesis methyltransferase YP_543368.1 4305282 D 364106 CDS YP_543369.1 91213383 3993365 4306006..4306656 1 NC_007946.1 hypothetical protein 4306656 yigP 3993365 yigP Escherichia coli UTI89 hypothetical protein YP_543369.1 4306006 D 364106 CDS YP_543370.1 91213384 3993366 4306653..4308293 1 NC_007946.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4308293 ubiB 3993366 ubiB Escherichia coli UTI89 ubiquinone biosynthesis protein UbiB YP_543370.1 4306653 D 364106 CDS YP_543371.1 91213385 3993367 4308330..4308641 1 NC_007946.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin-arginine translocation protein TatA 4308641 tatA 3993367 tatA Escherichia coli UTI89 twin-arginine translocation protein TatA YP_543371.1 4308330 D 364106 CDS YP_543372.1 91213386 3993368 4308645..4309160 1 NC_007946.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4309160 tatB 3993368 tatB Escherichia coli UTI89 sec-independent translocase YP_543372.1 4308645 D 364106 CDS YP_543373.1 91213387 3993369 4309163..4309939 1 NC_007946.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4309939 tatC 3993369 tatC Escherichia coli UTI89 twin-arginine protein translocation system subunit TatC YP_543373.1 4309163 D 364106 CDS YP_543374.1 91213388 3993832 4309969..4310763 1 NC_007946.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4310763 tatD 3993832 tatD Escherichia coli UTI89 DNase TatD YP_543374.1 4309969 D 364106 CDS YP_543375.1 91213389 3993833 complement(4310760..4311248) 1 NC_007946.1 transcriptional activator RfaH 4311248 rfaH 3993833 rfaH Escherichia coli UTI89 transcriptional activator RfaH YP_543375.1 4310760 R 364106 CDS YP_543376.1 91213390 3993834 4311415..4312908 1 NC_007946.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4312908 yigC 3993834 yigC Escherichia coli UTI89 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_543376.1 4311415 D 364106 CDS YP_543377.1 91213391 3993835 4312921..4313655 1 NC_007946.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4313655 fre 3993835 fre Escherichia coli UTI89 FMN reductase YP_543377.1 4312921 D 364106 CDS YP_543378.1 91213392 3993836 complement(4313938..4315101) 1 NC_007946.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4315101 fadA 3993836 fadA Escherichia coli UTI89 3-ketoacyl-CoA thiolase YP_543378.1 4313938 R 364106 CDS YP_543379.2 162138323 3993837 complement(4315111..4317300) 1 NC_007946.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4317300 fadB 3993837 fadB Escherichia coli UTI89 multifunctional fatty acid oxidation complex subunit alpha YP_543379.2 4315111 R 364106 CDS YP_543380.1 91213394 3993838 4317490..4318821 1 NC_007946.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4318821 pepQ 3993838 pepQ Escherichia coli UTI89 proline dipeptidase YP_543380.1 4317490 D 364106 CDS YP_543381.1 91213395 3993839 4318818..4319435 1 NC_007946.1 hypothetical protein 4319435 yigZ 3993839 yigZ Escherichia coli UTI89 hypothetical protein YP_543381.1 4318818 D 364106 CDS YP_543382.1 91213396 3993840 4319474..4320925 1 NC_007946.1 potassium transporter 4320925 trkH 3993840 trkH Escherichia coli UTI89 potassium transporter YP_543382.1 4319474 D 364106 CDS YP_543383.1 91213397 3993841 4320937..4321482 1 NC_007946.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4321482 hemG 3993841 hemG Escherichia coli UTI89 protoporphyrinogen oxidase YP_543383.1 4320937 D 364106 CDS YP_543386.1 91213400 3992601 complement(4327063..4327590) 1 NC_007946.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4327590 mobB 3992601 mobB Escherichia coli UTI89 molybdopterin-guanine dinucleotide biosynthesis protein B YP_543386.1 4327063 R 364106 CDS YP_543387.1 91213401 3992602 complement(4327572..4328156) 1 NC_007946.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4328156 mobA 3992602 mobA Escherichia coli UTI89 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_543387.1 4327572 R 364106 CDS YP_543388.1 91213402 3992603 4328196..4328495 1 NC_007946.1 hypothetical protein 4328495 yihD 3992603 yihD Escherichia coli UTI89 hypothetical protein YP_543388.1 4328196 D 364106 CDS YP_543389.1 91213403 3992604 4328572..4329558 1 NC_007946.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4329558 rdoA 3992604 rdoA Escherichia coli UTI89 serine/threonine protein kinase YP_543389.1 4328572 D 364106 CDS YP_543390.1 91213404 3992605 4329575..4330201 1 NC_007946.1 periplasmic protein disulfide isomerase I 4330201 dsbA 3992605 dsbA Escherichia coli UTI89 periplasmic protein disulfide isomerase I YP_543390.1 4329575 D 364106 CDS YP_543391.1 91213405 3992606 4330226..4330366 1 NC_007946.1 hypothetical protein 4330366 3992606 UTI89_C4448 Escherichia coli UTI89 hypothetical protein YP_543391.1 4330226 D 364106 CDS YP_543392.1 91213406 3992607 4330314..4331786 1 NC_007946.1 hypothetical protein 4331786 yihF 3992607 yihF Escherichia coli UTI89 hypothetical protein YP_543392.1 4330314 D 364106 CDS YP_543393.1 91213407 3992608 complement(4331827..4332783) 1 NC_007946.1 acyltransferase 4332783 yihG 3992608 yihG Escherichia coli UTI89 acyltransferase YP_543393.1 4331827 R 364106 CDS YP_543394.1 91213408 3992609 complement(4332879..4333121) 1 NC_007946.1 hypothetical protein 4333121 3992609 UTI89_C4451 Escherichia coli UTI89 hypothetical protein YP_543394.1 4332879 R 364106 CDS YP_543395.1 91213409 3992610 4333123..4335909 1 NC_007946.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4335909 polA 3992610 polA Escherichia coli UTI89 DNA polymerase I YP_543395.1 4333123 D 364106 CDS YP_543396.1 91213410 3992611 complement(4336128..4336277) 1 NC_007946.1 hypothetical protein 4336277 3992611 UTI89_C4453 Escherichia coli UTI89 hypothetical protein YP_543396.1 4336128 R 364106 CDS YP_543397.2 162138322 3992612 complement(4336291..4336923) 1 NC_007946.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4336923 engB 3992612 engB Escherichia coli UTI89 ribosome biogenesis GTP-binding protein YsxC YP_543397.2 4336291 R 364106 CDS YP_543398.1 91213412 3992613 4337505..4338014 1 NC_007946.1 hypothetical protein 4338014 yihI 3992613 yihI Escherichia coli UTI89 hypothetical protein YP_543398.1 4337505 D 364106 CDS YP_543399.1 91213413 3992614 4338197..4339576 1 NC_007946.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4339576 hemN 3992614 hemN Escherichia coli UTI89 coproporphyrinogen III oxidase YP_543399.1 4338197 D 364106 CDS YP_543400.2 162138321 3992615 complement(4339936..4341345) 1 NC_007946.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4341345 glnG 3992615 glnG Escherichia coli UTI89 nitrogen regulation protein NR(I) YP_543400.2 4339936 R 364106 CDS YP_543401.1 91213415 3992616 complement(4341357..4342406) 1 NC_007946.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4342406 glnL 3992616 glnL Escherichia coli UTI89 nitrogen regulation protein NR(II) YP_543401.1 4341357 R 364106 CDS YP_543402.1 91213416 3992617 complement(4342580..4343989) 1 NC_007946.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4343989 glnA 3992617 glnA Escherichia coli UTI89 glutamine synthetase YP_543402.1 4342580 R 364106 CDS YP_543403.1 91213417 3992430 4344362..4346185 1 NC_007946.1 synonym: b3871, bipA, yihK, yjhK; GTP-binding protein 4346185 typA 3992430 typA Escherichia coli UTI89 GTP-binding protein YP_543403.1 4344362 D 364106 CDS YP_543404.1 91213418 3992431 complement(4346292..4347080) 1 NC_007946.1 transcriptional regulator YihW 4347080 yihW 3992431 yihW Escherichia coli UTI89 transcriptional regulator YihW YP_543404.1 4346292 R 364106 CDS YP_543405.1 91213419 3992432 complement(4347120..4348067) 1 NC_007946.1 sugar kinase YihV 4348067 yihV 3992432 yihV Escherichia coli UTI89 sugar kinase YihV YP_543405.1 4347120 R 364106 CDS YP_543406.1 91213420 3992433 4348188..4349066 1 NC_007946.1 oxidoreductase YihU 4349066 yihU 3992433 yihU Escherichia coli UTI89 oxidoreductase YihU YP_543406.1 4348188 D 364106 CDS YP_543407.1 91213421 3992434 4349091..4349978 1 NC_007946.1 hypothetical protein 4349978 yihT 3992434 yihT Escherichia coli UTI89 hypothetical protein YP_543407.1 4349091 D 364106 CDS YP_543408.1 91213422 3992435 4350011..4351021 1 NC_007946.1 dehydrogenase 4351021 3992435 UTI89_C4465 Escherichia coli UTI89 dehydrogenase YP_543408.1 4350011 D 364106 CDS YP_543409.1 91213423 3992436 4351091..4352524 1 NC_007946.1 hypothetical protein 4352524 3992436 UTI89_C4466 Escherichia coli UTI89 hypothetical protein YP_543409.1 4351091 D 364106 CDS YP_543410.1 91213424 3992437 4352623..4353972 1 NC_007946.1 shikimate transporter 4353972 3992437 UTI89_C4467 Escherichia coli UTI89 shikimate transporter YP_543410.1 4352623 D 364106 CDS YP_543411.1 91213425 3992438 4353905..4354849 1 NC_007946.1 hypothetical protein 4354849 3992438 UTI89_C4468 Escherichia coli UTI89 hypothetical protein YP_543411.1 4353905 D 364106 CDS YP_543412.1 91213426 3992439 4354969..4355589 1 NC_007946.1 phosphatase 4355589 yihX 3992439 yihX Escherichia coli UTI89 phosphatase YP_543412.1 4354969 D 364106 CDS YP_543413.1 91213427 3992440 4355583..4356455 1 NC_007946.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4356455 rbn 3992440 rbn Escherichia coli UTI89 ribonuclease BN YP_543413.1 4355583 D 364106 CDS YP_543414.1 91213428 3992441 4356452..4356889 1 NC_007946.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4356889 yihZ 3992441 yihZ Escherichia coli UTI89 D-tyrosyl-tRNA(Tyr) deacylase YP_543414.1 4356452 D 364106 CDS YP_543415.1 91213429 3992442 4356886..4357875 1 NC_007946.1 acetyltransferase 4357875 yiiD 3992442 yiiD Escherichia coli UTI89 acetyltransferase YP_543415.1 4356886 D 364106 CDS YP_543416.1 91213430 3992443 complement(4357939..4358859) 1 NC_007946.1 lipase 4358859 3992443 UTI89_C4473 Escherichia coli UTI89 lipase YP_543416.1 4357939 R 364106 CDS YP_543417.1 91213431 3992444 4359076..4359387 1 NC_007946.1 hypothetical protein 4359387 3992444 UTI89_C4474 Escherichia coli UTI89 hypothetical protein YP_543417.1 4359076 D 364106 CDS YP_543418.1 91213432 3992445 4359388..4359678 1 NC_007946.1 hypothetical protein 4359678 3992445 UTI89_C4475 Escherichia coli UTI89 hypothetical protein YP_543418.1 4359388 D 364106 CDS YP_543419.1 91213433 3992446 4360037..4360315 1 NC_007946.1 hypothetical protein 4360315 3992446 UTI89_C4476 Escherichia coli UTI89 hypothetical protein YP_543419.1 4360037 D 364106 CDS YP_543420.1 91213434 3992447 4360684..4360929 1 NC_007946.1 hypothetical protein 4360929 yiiE 3992447 yiiE Escherichia coli UTI89 hypothetical protein YP_543420.1 4360684 D 364106 CDS YP_543421.1 91213435 3992448 complement(4361145..4362074) 1 NC_007946.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4362074 fdhE 3992448 fdhE Escherichia coli UTI89 formate dehydrogenase accessory protein FdhE YP_543421.1 4361145 R 364106 CDS YP_543422.1 91213436 3992449 complement(4362071..4362706) 1 NC_007946.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4362706 fdoI 3992449 fdoI Escherichia coli UTI89 formate dehydrogenase-O subunit gamma YP_543422.1 4362071 R 364106 CDS YP_543423.1 91213437 3992411 complement(4362703..4363605) 1 NC_007946.1 formate dehydrogenase-O, iron-sulfur subunit 4363605 fdoH 3992411 fdoH Escherichia coli UTI89 formate dehydrogenase-O, iron-sulfur subunit YP_543423.1 4362703 R 364106 CDS YP_543424.1 91213438 3992412 4366300..4366926 1 NC_007946.1 hypothetical protein 4366926 3992412 UTI89_C4481 Escherichia coli UTI89 hypothetical protein YP_543424.1 4366300 D 364106 CDS YP_543425.1 91213439 3992413 4366862..4367695 1 NC_007946.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4367695 fdhD 3992413 fdhD Escherichia coli UTI89 formate dehydrogenase accessory protein YP_543425.1 4366862 D 364106 CDS YP_543426.1 91213440 3992414 4368825..4370219 1 NC_007946.1 glycoporin 4370219 3992414 UTI89_C4483 Escherichia coli UTI89 glycoporin YP_543426.1 4368825 D 364106 CDS YP_543427.1 91213441 3992415 complement(4370260..4370574) 1 NC_007946.1 hypothetical protein 4370574 yiiL 3992415 yiiL Escherichia coli UTI89 hypothetical protein YP_543427.1 4370260 R 364106 CDS YP_543428.1 91213442 3992416 complement(4370584..4371501) 1 NC_007946.1 rhamnulose-1-phosphate aldolase 4371501 rhaD 3992416 rhaD Escherichia coli UTI89 rhamnulose-1-phosphate aldolase YP_543428.1 4370584 R 364106 CDS YP_543429.1 91213443 3992417 complement(4371685..4372950) 1 NC_007946.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4372950 rhaA 3992417 rhaA Escherichia coli UTI89 L-rhamnose isomerase YP_543429.1 4371685 R 364106 CDS YP_543430.1 91213444 3992418 complement(4372941..4374410) 1 NC_007946.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4374410 rhaB 3992418 rhaB Escherichia coli UTI89 rhamnulokinase YP_543430.1 4372941 R 364106 CDS YP_543431.1 91213445 3992419 4374698..4375534 1 NC_007946.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4375534 rhaS 3992419 rhaS Escherichia coli UTI89 transcriptional activator RhaS YP_543431.1 4374698 D 364106 CDS YP_543432.1 91213446 3992420 4375497..4376456 1 NC_007946.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4376456 rhaR 3992420 rhaR Escherichia coli UTI89 transcriptional activator RhaR YP_543432.1 4375497 D 364106 CDS YP_543433.1 91213447 3992421 complement(4376453..4377487) 1 NC_007946.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4377487 rhaT 3992421 rhaT Escherichia coli UTI89 rhamnose-proton symporter YP_543433.1 4376453 R 364106 CDS YP_543434.1 91213448 3992422 4377766..4378392 1 NC_007946.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4378392 sodA 3992422 sodA Escherichia coli UTI89 superoxide dismutase YP_543434.1 4377766 D 364106 CDS YP_543435.1 91213449 3992423 complement(4378421..4378549) 1 NC_007946.1 hypothetical protein 4378549 3992423 UTI89_C4492 Escherichia coli UTI89 hypothetical protein YP_543435.1 4378421 R 364106 CDS YP_543436.2 162138320 3992424 4378652..4379635 1 NC_007946.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4379635 kdgT 3992424 kdgT Escherichia coli UTI89 2-keto-3-deoxygluconate permease YP_543436.2 4378652 D 364106 CDS YP_543437.2 162138319 3992425 4379784..4380458 1 NC_007946.1 hypothetical protein 4380458 yiiM 3992425 yiiM Escherichia coli UTI89 hypothetical protein YP_543437.2 4379784 D 364106 CDS YP_543438.1 91213452 3992426 complement(4380564..4381937) 1 NC_007946.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4381937 cpxA 3992426 cpxA Escherichia coli UTI89 two-component sensor protein YP_543438.1 4380564 R 364106 CDS YP_543439.1 91213453 3992427 complement(4381934..4382632) 1 NC_007946.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4382632 cpxR 3992427 cpxR Escherichia coli UTI89 DNA-binding transcriptional regulator CpxR YP_543439.1 4381934 R 364106 CDS YP_543440.2 162138318 3992428 4382782..4383282 1 NC_007946.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4383282 cpxP 3992428 cpxP Escherichia coli UTI89 periplasmic repressor CpxP YP_543440.2 4382782 D 364106 CDS YP_543441.2 162138317 3992429 4383431..4384333 1 NC_007946.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4384333 fieF 3992429 fieF Escherichia coli UTI89 ferrous iron efflux protein F YP_543441.2 4383431 D 364106 CDS YP_543442.1 91213456 3994174 4384418..4385476 1 NC_007946.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4385476 pfkA 3994174 pfkA Escherichia coli UTI89 6-phosphofructokinase YP_543442.1 4384418 D 364106 CDS YP_543443.1 91213457 3994175 4385735..4385872 1 NC_007946.1 hypothetical protein 4385872 3994175 UTI89_C4500 Escherichia coli UTI89 hypothetical protein YP_543443.1 4385735 D 364106 CDS YP_543444.1 91213458 3994176 4385796..4386785 1 NC_007946.1 sulfate transporter subunit 4386785 sbp 3994176 sbp Escherichia coli UTI89 sulfate transporter subunit YP_543444.1 4385796 D 364106 CDS YP_543445.1 91213459 3994177 4386700..4387647 1 NC_007946.1 CDP-diacylglycerol pyrophosphatase 4387647 cdh 3994177 cdh Escherichia coli UTI89 CDP-diacylglycerol pyrophosphatase YP_543445.1 4386700 D 364106 CDS YP_543446.1 91213460 3994178 complement(4387702..4388469) 1 NC_007946.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4388469 tpiA 3994178 tpiA Escherichia coli UTI89 triosephosphate isomerase YP_543446.1 4387702 R 364106 CDS YP_543447.1 91213461 3994179 complement(4388577..4389176) 1 NC_007946.1 hypothetical protein 4389176 yiiQ 3994179 yiiQ Escherichia coli UTI89 hypothetical protein YP_543447.1 4388577 R 364106 CDS YP_543448.1 91213462 3994180 4389277..4389717 1 NC_007946.1 hypothetical protein 4389717 yiiR 3994180 yiiR Escherichia coli UTI89 hypothetical protein YP_543448.1 4389277 D 364106 CDS YP_543449.1 91213463 3994181 4389929..4390228 1 NC_007946.1 hypothetical protein 4390228 yiiS 3994181 yiiS Escherichia coli UTI89 hypothetical protein YP_543449.1 4389929 D 364106 CDS YP_543450.1 91213464 3994182 4390255..4390683 1 NC_007946.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4390683 yiiT 3994182 yiiT Escherichia coli UTI89 universal stress protein UspD YP_543450.1 4390255 D 364106 CDS YP_543451.1 91213465 3994183 complement(4390688..4391434) 1 NC_007946.1 synonym: flxR, b3924, G7964, fruB, mvrA; ferredoxin-NADP reductase 4391434 fpr 3994183 fpr Escherichia coli UTI89 ferredoxin-NADP reductase YP_543451.1 4390688 R 364106 CDS YP_543452.1 91213466 3994184 complement(4391531..4392541) 1 NC_007946.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4392541 glpX 3994184 glpX Escherichia coli UTI89 fructose 1,6-bisphosphatase II YP_543452.1 4391531 R 364106 CDS YP_543453.1 91213467 3994185 complement(4392712..4394325) 1 NC_007946.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4394325 glpK 3994185 glpK Escherichia coli UTI89 glycerol kinase YP_543453.1 4392712 R 364106 CDS YP_543454.1 91213468 3994186 complement(4394243..4395088) 1 NC_007946.1 glycerol MIP channel 4395088 glpF 3994186 glpF Escherichia coli UTI89 glycerol MIP channel YP_543454.1 4394243 R 364106 CDS YP_543455.1 91213469 3994187 4395495..4395758 1 NC_007946.1 hypothetical protein 4395758 yiiU 3994187 yiiU Escherichia coli UTI89 hypothetical protein YP_543455.1 4395495 D 364106 CDS YP_543456.1 91213470 3994188 complement(4395843..4396328) 1 NC_007946.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4396328 menG 3994188 menG Escherichia coli UTI89 ribonuclease activity regulator protein RraA YP_543456.1 4395843 R 364106 CDS YP_543457.1 91213471 3994189 4395900..4396406 1 NC_007946.1 hypothetical protein 4396406 3994189 UTI89_C4514 Escherichia coli UTI89 hypothetical protein YP_543457.1 4395900 D 364106 CDS YP_543458.1 91213472 3994190 complement(4396421..4397359) 1 NC_007946.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4397359 menA 3994190 menA Escherichia coli UTI89 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_543458.1 4396421 R 364106 CDS YP_543459.1 91213473 3994191 complement(4397414..4398745) 1 NC_007946.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4398745 hslU 3994191 hslU Escherichia coli UTI89 ATP-dependent protease ATP-binding subunit HslU YP_543459.1 4397414 R 364106 CDS YP_543460.1 91213474 3994192 complement(4398755..4399285) 1 NC_007946.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4399285 hslV 3994192 hslV Escherichia coli UTI89 ATP-dependent protease peptidase subunit YP_543460.1 4398755 R 364106 CDS YP_543461.1 91213475 3994193 complement(4399378..4400337) 1 NC_007946.1 essential cell division protein FtsN 4400337 ftsN 3994193 ftsN Escherichia coli UTI89 essential cell division protein FtsN YP_543461.1 4399378 R 364106 CDS YP_543462.1 91213476 3992562 complement(4400429..4401454) 1 NC_007946.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4401454 cytR 3992562 cytR Escherichia coli UTI89 DNA-binding transcriptional regulator CytR YP_543462.1 4400429 R 364106 CDS YP_543463.1 91213477 3992563 complement(4401610..4403880) 1 NC_007946.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4403880 priA 3992563 priA Escherichia coli UTI89 primosome assembly protein PriA YP_543463.1 4401610 R 364106 CDS YP_543464.1 91213478 3992564 complement(4403993..4404133) 1 NC_007946.1 hypothetical protein 4404133 3992564 UTI89_C4521 Escherichia coli UTI89 hypothetical protein YP_543464.1 4403993 R 364106 CDS YP_543465.1 91213479 3992565 complement(4404284..4404892) 1 NC_007946.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 4404892 yiiX 3992565 yiiX Escherichia coli UTI89 peptidoglycan peptidase YP_543465.1 4404284 R 364106 CDS YP_543466.1 91213480 3992566 complement(4404952..4405407) 1 NC_007946.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4405407 metJ 3992566 metJ Escherichia coli UTI89 transcriptional repressor protein MetJ YP_543466.1 4404952 R 364106 CDS YP_543467.1 91213481 3992567 4405432..4406706 1 NC_007946.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4406706 metB 3992567 metB Escherichia coli UTI89 cystathionine gamma-synthase YP_543467.1 4405432 D 364106 CDS YP_543468.1 91213482 3992568 4406709..4409141 1 NC_007946.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4409141 metL 3992568 metL Escherichia coli UTI89 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_543468.1 4406709 D 364106 CDS YP_543469.1 91213483 3992569 complement(4409359..4410219) 1 NC_007946.1 bifunctional nucleoside and albicidin permease/phage T6 and colicin K receptor 4410219 3992569 UTI89_C4526 Escherichia coli UTI89 bifunctional nucleoside and albicidin permease/phage T6 and colicin K receptor YP_543469.1 4409359 R 364106 CDS YP_543470.1 91213484 3992570 complement(4410296..4411921) 1 NC_007946.1 hypothetical protein 4411921 3992570 UTI89_C4527 Escherichia coli UTI89 hypothetical protein YP_543470.1 4410296 R 364106 CDS YP_543471.1 91213485 3992571 complement(4411956..4413509) 1 NC_007946.1 hypothetical protein 4413509 3992571 UTI89_C4528 Escherichia coli UTI89 hypothetical protein YP_543471.1 4411956 R 364106 CDS YP_543472.1 91213486 3992572 complement(4413739..4414863) 1 NC_007946.1 hypothetical protein 4414863 3992572 UTI89_C4529 Escherichia coli UTI89 hypothetical protein YP_543472.1 4413739 R 364106 CDS YP_543473.1 91213487 3992573 4414990..4416549 1 NC_007946.1 hypothetical protein 4416549 3992573 UTI89_C4530 Escherichia coli UTI89 hypothetical protein YP_543473.1 4414990 D 364106 CDS YP_543474.1 91213488 3992574 4416931..4417821 1 NC_007946.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4417821 metF 3992574 metF Escherichia coli UTI89 5,10-methylenetetrahydrofolate reductase YP_543474.1 4416931 D 364106 CDS YP_543475.1 91213489 3992575 4418111..4420330 1 NC_007946.1 bifunctional catalase HPI/peroxidase HPI 4420330 katG 3992575 katG Escherichia coli UTI89 bifunctional catalase HPI/peroxidase HPI YP_543475.1 4418111 D 364106 CDS YP_543476.1 91213490 3992576 4420358..4421329 1 NC_007946.1 transport protein YijE 4421329 yijE 3992576 yijE Escherichia coli UTI89 transport protein YijE YP_543476.1 4420358 D 364106 CDS YP_543477.1 91213491 3992577 complement(4421356..4421973) 1 NC_007946.1 hypothetical protein 4421973 yijF 3992577 yijF Escherichia coli UTI89 hypothetical protein YP_543477.1 4421356 R 364106 CDS YP_543478.1 91213492 3992578 complement(4421873..4422067) 1 NC_007946.1 hypothetical protein 4422067 3992578 UTI89_C4535 Escherichia coli UTI89 hypothetical protein YP_543478.1 4421873 R 364106 CDS YP_543479.1 91213493 3992579 complement(4422249..4423391) 1 NC_007946.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4423391 gldA 3992579 gldA Escherichia coli UTI89 glycerol dehydrogenase YP_543479.1 4422249 R 364106 CDS YP_543480.1 91213494 3992580 complement(4423363..4424025) 1 NC_007946.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4424025 talC 3992580 talC Escherichia coli UTI89 fructose-6-phosphate aldolase YP_543480.1 4423363 R 364106 CDS YP_543481.1 91213495 3993292 complement(4424037..4426538) 1 NC_007946.1 phosphoenolpyruvate-protein phosphotransferase ptsA 4426538 ptsA 3993292 ptsA Escherichia coli UTI89 phosphoenolpyruvate-protein phosphotransferase ptsA YP_543481.1 4424037 R 364106 CDS YP_543482.1 91213496 3993293 4426847..4427926 1 NC_007946.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4427926 frwC 3993293 frwC Escherichia coli UTI89 fructose-like permease EIIC subunit 2 YP_543482.1 4426847 D 364106 CDS YP_543483.1 91213497 3993294 4427941..4428261 1 NC_007946.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4428261 frwB 3993294 frwB Escherichia coli UTI89 PTS system fructose-like transporter subunit EIIB YP_543483.1 4427941 D 364106 CDS YP_543484.1 91213498 3993295 complement(4427974..4428300) 1 NC_007946.1 hypothetical protein 4428300 3993295 UTI89_C4541 Escherichia coli UTI89 hypothetical protein YP_543484.1 4427974 R 364106 CDS YP_543485.1 91213499 3993296 4428312..4430609 1 NC_007946.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4430609 pflD 3993296 pflD Escherichia coli UTI89 formate acetyltransferase 2 YP_543485.1 4428312 D 364106 CDS YP_543486.1 91213500 3993297 4430575..4431453 1 NC_007946.1 pyruvate formate lyase II activase 4431453 pflC 3993297 pflC Escherichia coli UTI89 pyruvate formate lyase II activase YP_543486.1 4430575 D 364106 CDS YP_543487.1 91213501 3993298 4431455..4431796 1 NC_007946.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4431796 frwD 3993298 frwD Escherichia coli UTI89 fructose-like phosphotransferase EIIB subunit 3 YP_543487.1 4431455 D 364106 CDS YP_543488.1 91213502 3993299 complement(4431783..4432634) 1 NC_007946.1 transcriptional regulator YijO 4432634 yijO 3993299 yijO Escherichia coli UTI89 transcriptional regulator YijO YP_543488.1 4431783 R 364106 CDS YP_543489.1 91213503 3993300 complement(4432860..4434638) 1 NC_007946.1 hypothetical protein 4434638 yijP 3993300 yijP Escherichia coli UTI89 hypothetical protein YP_543489.1 4432860 R 364106 CDS YP_543490.1 91213504 3993301 complement(4434776..4437427) 1 NC_007946.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4437427 ppc 3993301 ppc Escherichia coli UTI89 phosphoenolpyruvate carboxylase YP_543490.1 4434776 R 364106 CDS YP_543491.1 91213505 3993302 complement(4437729..4438919) 1 NC_007946.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4438919 argE 3993302 argE Escherichia coli UTI89 acetylornithine deacetylase YP_543491.1 4437729 R 364106 CDS YP_543492.1 91213506 3993303 4439034..4440038 1 NC_007946.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4440038 argC 3993303 argC Escherichia coli UTI89 N-acetyl-gamma-glutamyl-phosphate reductase YP_543492.1 4439034 D 364106 CDS YP_543493.1 91213507 3993304 4440013..4440822 1 NC_007946.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4440822 argB 3993304 argB Escherichia coli UTI89 acetylglutamate kinase YP_543493.1 4440013 D 364106 CDS YP_543494.1 91213508 3993305 4440883..4442256 1 NC_007946.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4442256 argH 3993305 argH Escherichia coli UTI89 argininosuccinate lyase YP_543494.1 4440883 D 364106 CDS YP_543495.1 91213509 3993306 4442754..4443968 1 NC_007946.1 starvation sensing protein RspA 4443968 3993306 UTI89_C4552 Escherichia coli UTI89 starvation sensing protein RspA YP_543495.1 4442754 D 364106 CDS YP_543496.1 91213510 3993307 4444035..4445318 1 NC_007946.1 transport protein YjjL 4445318 yjiZ 3993307 yjiZ Escherichia coli UTI89 transport protein YjjL YP_543496.1 4444035 D 364106 CDS YP_543497.2 162138316 3993308 4445570..4446487 1 NC_007946.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4446487 oxyR 3993308 oxyR Escherichia coli UTI89 DNA-binding transcriptional regulator OxyR YP_543497.2 4445570 D 364106 CDS YP_543498.1 91213512 3993309 complement(4446470..4447870) 1 NC_007946.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4447870 sthA 3993309 sthA Escherichia coli UTI89 soluble pyridine nucleotide transhydrogenase YP_543498.1 4446470 R 364106 CDS YP_543499.1 91213513 3993310 4448200..4449366 1 NC_007946.1 hippuricase 4449366 3993310 UTI89_C4556 Escherichia coli UTI89 hippuricase YP_543499.1 4448200 D 364106 CDS YP_543500.1 91213514 3993311 4449409..4450725 1 NC_007946.1 citrate permease 4450725 3993311 UTI89_C4557 Escherichia coli UTI89 citrate permease YP_543500.1 4449409 D 364106 CDS YP_543501.1 91213515 3994348 4450775..4451479 1 NC_007946.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4451479 yijC 3994348 yijC Escherichia coli UTI89 DNA-binding transcriptional repressor FabR YP_543501.1 4450775 D 364106 CDS YP_543502.1 91213516 3994349 4451479..4451838 1 NC_007946.1 hypothetical protein 4451838 yijD 3994349 yijD Escherichia coli UTI89 hypothetical protein YP_543502.1 4451479 D 364106 CDS YP_543503.1 91213517 3994350 complement(4451878..4452978) 1 NC_007946.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4452978 trmA 3994350 trmA Escherichia coli UTI89 tRNA (uracil-5-)-methyltransferase YP_543503.1 4451878 R 364106 CDS YP_543504.1 91213518 3994351 4453302..4455191 1 NC_007946.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4455191 btuB 3994351 btuB Escherichia coli UTI89 vitamin B12/cobalamin outer membrane transporter YP_543504.1 4453302 D 364106 CDS YP_543505.1 91213519 3994352 4455136..4455993 1 NC_007946.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4455993 murI 3994352 murI Escherichia coli UTI89 glutamate racemase YP_543505.1 4455136 D 364106 CDS YP_543509.1 91213523 3994360 4461423..4461842 1 NC_007946.1 hypothetical protein 4461842 yjaA 3994360 yjaA Escherichia coli UTI89 hypothetical protein YP_543509.1 4461423 D 364106 CDS YP_543510.1 91213524 3994361 complement(4461906..4462349) 1 NC_007946.1 hypothetical protein 4462349 yjaB 3994361 yjaB Escherichia coli UTI89 hypothetical protein YP_543510.1 4461906 R 364106 CDS YP_543511.1 91213525 3994362 4462506..4463435 1 NC_007946.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4463435 metA 3994362 metA Escherichia coli UTI89 homoserine O-succinyltransferase YP_543511.1 4462506 D 364106 CDS YP_543512.1 91213526 3991698 4463686..4465305 1 NC_007946.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4465305 aceB 3991698 aceB Escherichia coli UTI89 malate synthase YP_543512.1 4463686 D 364106 CDS YP_543513.1 91213527 3991699 4465320..4466639 1 NC_007946.1 isocitrate lyase 4466639 aceA 3991699 aceA Escherichia coli UTI89 isocitrate lyase YP_543513.1 4465320 D 364106 CDS YP_543514.1 91213528 3991700 4466688..4468412 1 NC_007946.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4468412 aceK 3991700 aceK Escherichia coli UTI89 bifunctional isocitrate dehydrogenase kinase/phosphatase YP_543514.1 4466688 D 364106 CDS YP_543515.2 162138315 3991701 complement(4468429..4469253) 1 NC_007946.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR 4469253 iclR 3991701 iclR Escherichia coli UTI89 transcriptional repressor IclR YP_543515.2 4468429 R 364106 CDS YP_543516.1 91213530 3991702 4469453..4473136 1 NC_007946.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4473136 metH 3991702 metH Escherichia coli UTI89 B12-dependent methionine synthase YP_543516.1 4469453 D 364106 CDS YP_543517.1 91213531 3991703 4473190..4473516 1 NC_007946.1 hypothetical protein 4473516 3991703 UTI89_C4578 Escherichia coli UTI89 hypothetical protein YP_543517.1 4473190 D 364106 CDS YP_543518.1 91213532 3991704 4473559..4474008 1 NC_007946.1 hypothetical protein 4474008 3991704 UTI89_C4579 Escherichia coli UTI89 hypothetical protein YP_543518.1 4473559 D 364106 CDS YP_543519.1 91213533 3991705 4474179..4475810 1 NC_007946.1 hypothetical protein 4475810 yjbB 3991705 yjbB Escherichia coli UTI89 hypothetical protein YP_543519.1 4474179 D 364106 CDS YP_543520.1 91213534 3991706 complement(4475900..4476589) 1 NC_007946.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4476589 pepE 3991706 pepE Escherichia coli UTI89 peptidase E YP_543520.1 4475900 R 364106 CDS YP_543521.1 91213535 3991707 4476696..4476851 1 NC_007946.1 hypothetical protein 4476851 3991707 UTI89_C4582 Escherichia coli UTI89 hypothetical protein YP_543521.1 4476696 D 364106 CDS YP_543522.1 91213536 3991708 complement(4476971..4478200) 1 NC_007946.1 oxidoreductase 4478200 3991708 UTI89_C4583 Escherichia coli UTI89 oxidoreductase YP_543522.1 4476971 R 364106 CDS YP_543523.1 91213537 3991709 complement(4478252..4479106) 1 NC_007946.1 PTS system mannose-specific transporter subunit IID 4479106 3991709 UTI89_C4584 Escherichia coli UTI89 PTS system mannose-specific transporter subunit IID YP_543523.1 4478252 R 364106 CDS YP_543524.1 91213538 3991710 complement(4479087..4479884) 1 NC_007946.1 PTS system mannose-specific transporter subunit IIC 4479884 3991710 UTI89_C4585 Escherichia coli UTI89 PTS system mannose-specific transporter subunit IIC YP_543524.1 4479087 R 364106 CDS YP_543525.1 91213539 3991711 complement(4479950..4480444) 1 NC_007946.1 sorbose PTS component 4480444 3991711 UTI89_C4586 Escherichia coli UTI89 sorbose PTS component YP_543525.1 4479950 R 364106 CDS YP_543526.1 91213540 3991712 complement(4480444..4480851) 1 NC_007946.1 sorbose PTS component 4480851 3991712 UTI89_C4587 Escherichia coli UTI89 sorbose PTS component YP_543526.1 4480444 R 364106 CDS YP_543527.1 91213541 3991713 complement(4480861..4481667) 1 NC_007946.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 4481667 3991713 UTI89_C4588 Escherichia coli UTI89 sorbitol-6-phosphate 2-dehydrogenase YP_543527.1 4480861 R 364106 CDS YP_543528.1 91213542 3991714 complement(4481737..4482768) 1 NC_007946.1 sorbose uptake and utilization transcriptional regulator 4482768 3991714 UTI89_C4589 Escherichia coli UTI89 sorbose uptake and utilization transcriptional regulator YP_543528.1 4481737 R 364106 CDS YP_543529.1 91213543 3991715 4483032..4483904 1 NC_007946.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4483904 yjbC 3991715 yjbC Escherichia coli UTI89 23S rRNA pseudouridine synthase F YP_543529.1 4483032 D 364106 CDS YP_543530.1 91213544 3991716 complement(4483905..4484177) 1 NC_007946.1 hypothetical protein 4484177 yjbD 3991716 yjbD Escherichia coli UTI89 hypothetical protein YP_543530.1 4483905 R 364106 CDS YP_543531.1 91213545 3991717 complement(4484430..4485779) 1 NC_007946.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 4485779 lysC 3991717 lysC Escherichia coli UTI89 aspartate kinase YP_543531.1 4484430 R 364106 CDS YP_543532.1 91213546 3991070 4486298..4487953 1 NC_007946.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4487953 pgi 3991070 pgi Escherichia coli UTI89 glucose-6-phosphate isomerase YP_543532.1 4486298 D 364106 CDS YP_543534.1 91213548 3991072 4488778..4489446 1 NC_007946.1 hypothetical protein 4489446 3991072 UTI89_C4595 Escherichia coli UTI89 hypothetical protein YP_543534.1 4488778 D 364106 CDS YP_543535.1 91213549 3991073 4489443..4490180 1 NC_007946.1 hypothetical protein 4490180 yjbG 3991073 yjbG Escherichia coli UTI89 hypothetical protein YP_543535.1 4489443 D 364106 CDS YP_543536.1 91213550 3991074 4490180..4492276 1 NC_007946.1 hypothetical protein 4492276 yjbH 3991074 yjbH Escherichia coli UTI89 hypothetical protein YP_543536.1 4490180 D 364106 CDS YP_543537.1 91213551 3991075 4492280..4492441 1 NC_007946.1 hypothetical protein 4492441 3991075 UTI89_C4598 Escherichia coli UTI89 hypothetical protein YP_543537.1 4492280 D 364106 CDS YP_543538.1 91213552 3991076 complement(4492323..4492601) 1 NC_007946.1 hypothetical protein 4492601 3991076 UTI89_C4599 Escherichia coli UTI89 hypothetical protein YP_543538.1 4492323 R 364106 CDS YP_543539.1 91213553 3991077 complement(4492598..4492720) 1 NC_007946.1 hypothetical protein 4492720 3991077 UTI89_C4600 Escherichia coli UTI89 hypothetical protein YP_543539.1 4492598 R 364106 CDS YP_543540.1 91213554 3991078 4492816..4493226 1 NC_007946.1 phosphate-starvation-inducible protein PsiE 4493226 yjbA 3991078 yjbA Escherichia coli UTI89 phosphate-starvation-inducible protein PsiE YP_543540.1 4492816 D 364106 CDS YP_543541.1 91213555 3991079 complement(4493320..4494210) 1 NC_007946.1 with MalKFE is involved in the transport of maltose into the cell; maltose ABC transporter permease 4494210 malG 3991079 malG Escherichia coli UTI89 maltose ABC transporter permease YP_543541.1 4493320 R 364106 CDS YP_543542.1 91213556 3991080 complement(4494225..4495784) 1 NC_007946.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4495784 malF 3991080 malF Escherichia coli UTI89 maltose transporter membrane protein YP_543542.1 4494225 R 364106 CDS YP_543543.1 91213557 3991081 complement(4495923..4497113) 1 NC_007946.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter substrate-binding protein 4497113 malE 3991081 malE Escherichia coli UTI89 maltose ABC transporter substrate-binding protein YP_543543.1 4495923 R 364106 CDS YP_543544.1 91213558 3991082 4497388..4498593 1 NC_007946.1 with malEFG is involved in import of maltose/maltodextrin; maltose ABC transporter ATP-binding protein 4498593 malK 3991082 malK Escherichia coli UTI89 maltose ABC transporter ATP-binding protein YP_543544.1 4497388 D 364106 CDS YP_543545.1 91213559 3991083 4498665..4500005 1 NC_007946.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4500005 lamB 3991083 lamB Escherichia coli UTI89 maltoporin YP_543545.1 4498665 D 364106 CDS YP_543546.1 91213560 3991084 4500319..4501248 1 NC_007946.1 maltose regulon periplasmic protein 4501248 malM 3991084 malM Escherichia coli UTI89 maltose regulon periplasmic protein YP_543546.1 4500319 D 364106 CDS YP_543547.1 91213561 3991085 4501261..4501413 1 NC_007946.1 hypothetical protein 4501413 3991085 UTI89_C4608 Escherichia coli UTI89 hypothetical protein YP_543547.1 4501261 D 364106 CDS YP_543548.1 91213562 3991086 4501427..4501924 1 NC_007946.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4501924 ubiC 3991086 ubiC Escherichia coli UTI89 chorismate pyruvate lyase YP_543548.1 4501427 D 364106 CDS YP_543549.1 91213563 3991087 4501937..4502809 1 NC_007946.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4502809 ubiA 3991087 ubiA Escherichia coli UTI89 4-hydroxybenzoate octaprenyltransferase YP_543549.1 4501937 D 364106 CDS YP_543550.2 162138314 3991088 complement(4502962..4505385) 1 NC_007946.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4505385 plsB 3991088 plsB Escherichia coli UTI89 glycerol-3-phosphate acyltransferase YP_543550.2 4502962 R 364106 CDS YP_543551.1 91213565 3991089 4505556..4505924 1 NC_007946.1 diacylglycerol kinase 4505924 dgkA 3991089 dgkA Escherichia coli UTI89 diacylglycerol kinase YP_543551.1 4505556 D 364106 CDS YP_543552.1 91213566 3991090 4506034..4506642 1 NC_007946.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4506642 lexA 3991090 lexA Escherichia coli UTI89 LexA repressor YP_543552.1 4506034 D 364106 CDS YP_543553.1 91213567 3991091 4506661..4508040 1 NC_007946.1 DNA-damage-inducible SOS response protein 4508040 dinF 3991091 dinF Escherichia coli UTI89 DNA-damage-inducible SOS response protein YP_543553.1 4506661 D 364106 CDS YP_543554.1 91213568 3991092 4508150..4508365 1 NC_007946.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4508365 yjbJ 3991092 yjbJ Escherichia coli UTI89 stress-response protein YP_543554.1 4508150 D 364106 CDS YP_543555.2 162138313 3991093 complement(4508407..4508922) 1 NC_007946.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4508922 yjbK 3991093 yjbK Escherichia coli UTI89 zinc uptake transcriptional repressor YP_543555.2 4508407 R 364106 CDS YP_543556.1 91213570 3991094 4509078..4510073 1 NC_007946.1 tRNA-dihydrouridine synthase A 4510073 yjbN 3991094 yjbN Escherichia coli UTI89 tRNA-dihydrouridine synthase A YP_543556.1 4509078 D 364106 CDS YP_543557.1 91213571 3991095 4509997..4510449 1 NC_007946.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4510449 pspG 3991095 pspG Escherichia coli UTI89 phage shock protein G YP_543557.1 4509997 D 364106 CDS YP_543558.1 91213572 3991096 complement(4510614..4511597) 1 NC_007946.1 quinone oxidoreductase, NADPH-dependent 4511597 qor 3991096 qor Escherichia coli UTI89 quinone oxidoreductase, NADPH-dependent YP_543558.1 4510614 R 364106 CDS YP_543559.1 91213573 3991097 complement(4511703..4513868) 1 NC_007946.1 oxidoreductase 4513868 3991097 UTI89_C4620 Escherichia coli UTI89 oxidoreductase YP_543559.1 4511703 R 364106 CDS YP_543560.1 91213574 3991098 complement(4513741..4515141) 1 NC_007946.1 transmembrane transport protein 4515141 3991098 UTI89_C4621 Escherichia coli UTI89 transmembrane transport protein YP_543560.1 4513741 R 364106 CDS YP_543561.1 91213575 3991099 complement(4515232..4516011) 1 NC_007946.1 crotonase 4516011 3991099 UTI89_C4622 Escherichia coli UTI89 crotonase YP_543561.1 4515232 R 364106 CDS YP_543562.1 91213576 3991100 complement(4516004..4517575) 1 NC_007946.1 propionate CoA-transferase 4517575 3991100 UTI89_C4623 Escherichia coli UTI89 propionate CoA-transferase YP_543562.1 4516004 R 364106 CDS YP_543563.1 91213577 3991101 4517804..4518865 1 NC_007946.1 regulator 4518865 3991101 UTI89_C4624 Escherichia coli UTI89 regulator YP_543563.1 4517804 D 364106 CDS YP_543564.1 91213578 3991102 4518902..4520353 1 NC_007946.1 unwinds double stranded DNA; replicative DNA helicase 4520353 dnaB 3991102 dnaB Escherichia coli UTI89 replicative DNA helicase YP_543564.1 4518902 D 364106 CDS YP_543565.1 91213579 3991103 4520406..4521485 1 NC_007946.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4521485 alr 3991103 alr Escherichia coli UTI89 alanine racemase YP_543565.1 4520406 D 364106 CDS YP_543566.1 91213580 3991104 4521508..4522065 1 NC_007946.1 transporter 4522065 3991104 UTI89_C4627 Escherichia coli UTI89 transporter YP_543566.1 4521508 D 364106 CDS YP_543567.1 91213581 3991105 4522038..4523060 1 NC_007946.1 NadR transcriptional repressor / NMN adenylyltransferase 4523060 3991105 UTI89_C4628 Escherichia coli UTI89 NadR transcriptional repressor / NMN adenylyltransferase YP_543567.1 4522038 D 364106 CDS YP_543568.2 162138312 3991106 4523142..4524335 1 NC_007946.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4524335 tyrB 3991106 tyrB Escherichia coli UTI89 aromatic amino acid aminotransferase YP_543568.2 4523142 D 364106 CDS YP_543569.1 91213583 3991107 4524442..4527261 1 NC_007946.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4527261 sucA 3991107 sucA Escherichia coli UTI89 2-oxoglutarate dehydrogenase E1 YP_543569.1 4524442 D 364106 CDS YP_543570.1 91213584 3991108 complement(4527134..4527334) 1 NC_007946.1 hypothetical protein 4527334 3991108 UTI89_C4631 Escherichia coli UTI89 hypothetical protein YP_543570.1 4527134 R 364106 CDS YP_543571.1 91213585 3991109 4527393..4528448 1 NC_007946.1 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 4528448 3991109 UTI89_C4632 Escherichia coli UTI89 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex YP_543571.1 4527393 D 364106 CDS YP_543572.1 91213586 3991110 4528460..4529878 1 NC_007946.1 subunit of 2-oxoglutarate dehydrogenase 4529878 3991110 UTI89_C4633 Escherichia coli UTI89 subunit of 2-oxoglutarate dehydrogenase YP_543572.1 4528460 D 364106 CDS YP_543573.1 91213587 3991111 4529900..4531069 1 NC_007946.1 SucC, succinyl-CoA synthetase subunit beta 4531069 3991111 UTI89_C4634 Escherichia coli UTI89 SucC, succinyl-CoA synthetase subunit beta YP_543573.1 4529900 D 364106 CDS YP_543574.1 91213588 3991112 4531082..4531954 1 NC_007946.1 SucD, succinyl-CoA synthetase subunit alpha 4531954 3991112 UTI89_C4635 Escherichia coli UTI89 SucD, succinyl-CoA synthetase subunit alpha YP_543574.1 4531082 D 364106 CDS YP_543575.1 91213589 3991113 4532160..4533665 1 NC_007946.1 membrane-bound protein 4533665 3991113 UTI89_C4636 Escherichia coli UTI89 membrane-bound protein YP_543575.1 4532160 D 364106 CDS YP_543576.1 91213590 3991114 4533539..4534750 1 NC_007946.1 lactate dehydrogenase 4534750 3991114 UTI89_C4637 Escherichia coli UTI89 lactate dehydrogenase YP_543576.1 4533539 D 364106 CDS YP_543577.1 91213591 3991115 complement(4534739..4536097) 1 NC_007946.1 c4-dicarboxylate transport transcriptional regulatory protein 4536097 3991115 UTI89_C4638 Escherichia coli UTI89 c4-dicarboxylate transport transcriptional regulatory protein YP_543577.1 4534739 R 364106 CDS YP_543578.1 91213592 3991116 complement(4536090..4537910) 1 NC_007946.1 transport sensor protein 4537910 3991116 UTI89_C4639 Escherichia coli UTI89 transport sensor protein YP_543578.1 4536090 R 364106 CDS YP_543579.1 91213593 3991117 4538026..4538178 1 NC_007946.1 hypothetical protein 4538178 3991117 UTI89_C4640 Escherichia coli UTI89 hypothetical protein YP_543579.1 4538026 D 364106 CDS YP_543580.1 91213594 3991118 4538187..4538900 1 NC_007946.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4538900 aphA 3991118 aphA Escherichia coli UTI89 acid phosphatase/phosphotransferase YP_543580.1 4538187 D 364106 CDS YP_543581.1 91213595 3991119 4539011..4539427 1 NC_007946.1 hypothetical protein 4539427 yjbQ 3991119 yjbQ Escherichia coli UTI89 hypothetical protein YP_543581.1 4539011 D 364106 CDS YP_543582.1 91213596 3991120 4539431..4539787 1 NC_007946.1 hypothetical protein 4539787 yjbR 3991120 yjbR Escherichia coli UTI89 hypothetical protein YP_543582.1 4539431 D 364106 CDS YP_543583.1 91213597 3991121 complement(4539822..4542644) 1 NC_007946.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4542644 uvrA 3991121 uvrA Escherichia coli UTI89 excinuclease ABC subunit A YP_543583.1 4539822 R 364106 CDS YP_543584.2 162138311 3991122 4542898..4543434 1 NC_007946.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4543434 ssb 3991122 ssb Escherichia coli UTI89 single-stranded DNA-binding protein YP_543584.2 4542898 D 364106 CDS YP_543585.1 91213599 3991123 complement(4543533..4543913) 1 NC_007946.1 hypothetical protein 4543913 yjcB 3991123 yjcB Escherichia coli UTI89 hypothetical protein YP_543585.1 4543533 R 364106 CDS YP_543586.1 91213600 3991124 4544234..4545829 1 NC_007946.1 hypothetical protein 4545829 yjcC 3991124 yjcC Escherichia coli UTI89 hypothetical protein YP_543586.1 4544234 D 364106 CDS YP_543587.1 91213601 3991125 complement(4545832..4546155) 1 NC_007946.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4546155 soxS 3991125 soxS Escherichia coli UTI89 DNA-binding transcriptional regulator SoxS YP_543587.1 4545832 R 364106 CDS YP_543588.1 91213602 3991126 4546241..4546705 1 NC_007946.1 redox-sensitive transcriptional activator SoxR 4546705 soxR 3991126 soxR Escherichia coli UTI89 redox-sensitive transcriptional activator SoxR YP_543588.1 4546241 D 364106 CDS YP_543589.1 91213603 3991127 4546692..4546958 1 NC_007946.1 hypothetical protein 4546958 3991127 UTI89_C4650 Escherichia coli UTI89 hypothetical protein YP_543589.1 4546692 D 364106 CDS YP_543590.1 91213604 3989703 4547252..4548601 1 NC_007946.1 hypothetical protein 4548601 yjcD 3989703 yjcD Escherichia coli UTI89 hypothetical protein YP_543590.1 4547252 D 364106 CDS YP_543591.1 91213605 3989704 4548752..4550401 1 NC_007946.1 CPA1 transporter YjcE 4550401 yjcE 3989704 yjcE Escherichia coli UTI89 CPA1 transporter YjcE YP_543591.1 4548752 D 364106 CDS YP_543592.1 91213606 3989705 complement(4550437..4551321) 1 NC_007946.1 transcriptional regulator 4551321 3989705 UTI89_C4653 Escherichia coli UTI89 transcriptional regulator YP_543592.1 4550437 R 364106 CDS YP_543593.1 91213607 3989706 4551333..4551461 1 NC_007946.1 hypothetical protein 4551461 3989706 UTI89_C4654 Escherichia coli UTI89 hypothetical protein YP_543593.1 4551333 D 364106 CDS YP_543594.1 91213608 3989707 4551425..4551835 1 NC_007946.1 hypothetical protein 4551835 3989707 UTI89_C4655 Escherichia coli UTI89 hypothetical protein YP_543594.1 4551425 D 364106 CDS YP_543595.1 91213609 3989708 4551828..4552517 1 NC_007946.1 hypothetical protein 4552517 3989708 UTI89_C4656 Escherichia coli UTI89 hypothetical protein YP_543595.1 4551828 D 364106 CDS YP_543596.1 91213610 3989709 complement(4552556..4554205) 1 NC_007946.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4554205 actP 3989709 actP Escherichia coli UTI89 acetate permease YP_543596.1 4552556 R 364106 CDS YP_543597.1 91213611 3989710 complement(4554202..4554516) 1 NC_007946.1 hypothetical protein 4554516 yjcH 3989710 yjcH Escherichia coli UTI89 hypothetical protein YP_543597.1 4554202 R 364106 CDS YP_543598.1 91213612 3989711 complement(4554808..4556766) 1 NC_007946.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4556766 acs 3989711 acs Escherichia coli UTI89 acetyl-CoA synthetase YP_543598.1 4554808 R 364106 CDS YP_543599.1 91213613 3989712 4557158..4558594 1 NC_007946.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4558594 nrfA 3989712 nrfA Escherichia coli UTI89 cytochrome c552 YP_543599.1 4557158 D 364106 CDS YP_543600.1 91213614 3989713 4558633..4559205 1 NC_007946.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4559205 nrfB 3989713 nrfB Escherichia coli UTI89 cytochrome c nitrite reductase pentaheme subunit YP_543600.1 4558633 D 364106 CDS YP_543601.1 91213615 3989714 4559202..4559873 1 NC_007946.1 NrfC protein 4559873 nrfC 3989714 nrfC Escherichia coli UTI89 NrfC protein YP_543601.1 4559202 D 364106 CDS YP_543602.1 91213616 3989715 4559870..4560826 1 NC_007946.1 NrfD protein 4560826 nrfD 3989715 nrfD Escherichia coli UTI89 NrfD protein YP_543602.1 4559870 D 364106 CDS YP_543603.1 91213617 3989716 4560882..4562564 1 NC_007946.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4562564 nrfE 3989716 nrfE Escherichia coli UTI89 heme lyase subunit NrfE YP_543603.1 4560882 D 364106 CDS YP_543604.1 91213618 3989717 4562557..4562940 1 NC_007946.1 formate-dependent nitrite reductase complex subunit NrfF 4562940 nrfF 3989717 nrfF Escherichia coli UTI89 formate-dependent nitrite reductase complex subunit NrfF YP_543604.1 4562557 D 364106 CDS YP_543605.1 91213619 3989718 4562937..4563533 1 NC_007946.1 formate-dependent nitrite reductase complex subunit NrfG 4563533 nrfG 3989718 nrfG Escherichia coli UTI89 formate-dependent nitrite reductase complex subunit NrfG YP_543605.1 4562937 D 364106 CDS YP_543606.1 91213620 3989719 complement(4563668..4563799) 1 NC_007946.1 hypothetical protein 4563799 3989719 UTI89_C4667 Escherichia coli UTI89 hypothetical protein YP_543606.1 4563668 R 364106 CDS YP_543607.1 91213621 3989720 4563876..4565189 1 NC_007946.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4565189 gltP 3989720 gltP Escherichia coli UTI89 glutamate/aspartate:proton symporter YP_543607.1 4563876 D 364106 CDS YP_543608.1 91213622 3989721 complement(4565337..4566080) 1 NC_007946.1 hypothetical protein 4566080 yjcO 3989721 yjcO Escherichia coli UTI89 hypothetical protein YP_543608.1 4565337 R 364106 CDS YP_543609.1 91213623 3989722 complement(4566137..4566841) 1 NC_007946.1 ABC transporter ATP-binding protein 4566841 yddO 3989722 yddO Escherichia coli UTI89 ABC transporter ATP-binding protein YP_543609.1 4566137 R 364106 CDS YP_543610.1 91213624 3990593 complement(4566828..4567724) 1 NC_007946.1 oligopeptide ABC transporter 4567724 3990593 UTI89_C4671 Escherichia coli UTI89 oligopeptide ABC transporter YP_543610.1 4566828 R 364106 CDS YP_543611.1 91213625 3990594 complement(4567657..4568490) 1 NC_007946.1 ABC transporter permease 4568490 yddQ 3990594 yddQ Escherichia coli UTI89 ABC transporter permease YP_543611.1 4567657 R 364106 CDS YP_543612.1 91213626 3990595 complement(4568490..4569632) 1 NC_007946.1 ABC transporter permease 4569632 yddR 3990595 yddR Escherichia coli UTI89 ABC transporter permease YP_543612.1 4568490 R 364106 CDS YP_543613.1 91213627 3990596 complement(4569639..4571207) 1 NC_007946.1 hypothetical protein 4571207 3990596 UTI89_C4674 Escherichia coli UTI89 hypothetical protein YP_543613.1 4569639 R 364106 CDS YP_543614.1 91213628 3990597 complement(4573927..4575393) 1 NC_007946.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4575393 yjcP 3990597 yjcP Escherichia coli UTI89 outer membrane efflux protein MdtP YP_543614.1 4573927 R 364106 CDS YP_543615.1 91213629 3990598 complement(4575390..4577441) 1 NC_007946.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4577441 3990598 UTI89_C4676 Escherichia coli UTI89 multidrug efflux system protein MdtO YP_543615.1 4575390 R 364106 CDS YP_543616.1 91213630 3990599 complement(4577441..4578472) 1 NC_007946.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4578472 yjcR 3990599 yjcR Escherichia coli UTI89 multidrug resistance protein MdtN YP_543616.1 4577441 R 364106 CDS YP_543617.1 91213631 3990600 complement(4578491..4578814) 1 NC_007946.1 hypothetical protein 4578814 3990600 UTI89_C4678 Escherichia coli UTI89 hypothetical protein YP_543617.1 4578491 R 364106 CDS YP_543618.1 91213632 3990601 complement(4578974..4580971) 1 NC_007946.1 hypothetical protein 4580971 yjcS 3990601 yjcS Escherichia coli UTI89 hypothetical protein YP_543618.1 4578974 R 364106 CDS YP_543619.1 91213633 3990602 complement(4581234..4582163) 1 NC_007946.1 D-allose kinase 4582163 yjcT 3990602 yjcT Escherichia coli UTI89 D-allose kinase YP_543619.1 4581234 R 364106 CDS YP_543620.1 91213634 3990603 complement(4582147..4582848) 1 NC_007946.1 allulose-6-phosphate 3-epimerase 4582848 yjcU 3990603 yjcU Escherichia coli UTI89 allulose-6-phosphate 3-epimerase YP_543620.1 4582147 R 364106 CDS YP_543621.1 91213635 3990604 complement(4583812..4585344) 1 NC_007946.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4585344 alsA 3990604 alsA Escherichia coli UTI89 D-allose transporter ATP-binding protein YP_543621.1 4583812 R 364106 CDS YP_543622.1 91213636 3990605 complement(4585471..4586412) 1 NC_007946.1 D-allose transporter subunit 4586412 yjcX 3990605 yjcX Escherichia coli UTI89 D-allose transporter subunit YP_543622.1 4585471 R 364106 CDS YP_543623.2 162138310 3990606 complement(4586465..4587355) 1 NC_007946.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4587355 rpiR 3990606 rpiR Escherichia coli UTI89 DNA-binding transcriptional repressor RpiR YP_543623.2 4586465 R 364106 CDS YP_543624.1 91213638 3990607 4587715..4588164 1 NC_007946.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4588164 rpiB 3990607 rpiB Escherichia coli UTI89 ribose-5-phosphate isomerase B YP_543624.1 4587715 D 364106 CDS YP_543625.1 91213639 3990608 4588233..4588562 1 NC_007946.1 hypothetical protein 4588562 3990608 UTI89_C4686 Escherichia coli UTI89 hypothetical protein YP_543625.1 4588233 D 364106 CDS YP_543626.1 91213640 3990609 complement(4588590..4589348) 1 NC_007946.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4589348 phnP 3990609 phnP Escherichia coli UTI89 carbon-phosphorus lyase complex accessory protein YP_543626.1 4588590 R 364106 CDS YP_543627.1 91213641 3990610 complement(4589350..4589784) 1 NC_007946.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4589784 phnO 3990610 phnO Escherichia coli UTI89 aminoalkylphosphonic acid N-acetyltransferase YP_543627.1 4589350 R 364106 CDS YP_543628.1 91213642 3990611 complement(4589771..4590328) 1 NC_007946.1 ribose 1,5-bisphosphokinase 4590328 phnN 3990611 phnN Escherichia coli UTI89 ribose 1,5-bisphosphokinase YP_543628.1 4589771 R 364106 CDS YP_543629.1 91213643 3990957 complement(4590328..4591464) 1 NC_007946.1 PhnM protein 4591464 phnM 3990957 phnM Escherichia coli UTI89 PhnM protein YP_543629.1 4590328 R 364106 CDS YP_543630.1 91213644 3990958 complement(4591461..4592141) 1 NC_007946.1 phosphonates transport ATP-binding protein PhnL 4592141 phnL 3990958 phnL Escherichia coli UTI89 phosphonates transport ATP-binding protein PhnL YP_543630.1 4591461 R 364106 CDS YP_543631.2 162138309 3990959 complement(4592252..4593010) 1 NC_007946.1 phosphonate C-P lyase system protein PhnK 4593010 phnK 3990959 phnK Escherichia coli UTI89 phosphonate C-P lyase system protein PhnK YP_543631.2 4592252 R 364106 CDS YP_543632.1 91213646 3990960 complement(4593007..4593936) 1 NC_007946.1 PhnJ protein 4593936 phnJ 3990960 phnJ Escherichia coli UTI89 PhnJ protein YP_543632.1 4593007 R 364106 CDS YP_543633.1 91213647 3990961 complement(4593845..4594915) 1 NC_007946.1 PhnI protein 4594915 phnI 3990961 phnI Escherichia coli UTI89 PhnI protein YP_543633.1 4593845 R 364106 CDS YP_543634.1 91213648 3990962 complement(4594909..4595493) 1 NC_007946.1 carbon-phosphorus lyase complex subunit 4595493 phnH 3990962 phnH Escherichia coli UTI89 carbon-phosphorus lyase complex subunit YP_543634.1 4594909 R 364106 CDS YP_543635.1 91213649 3990963 complement(4595490..4595942) 1 NC_007946.1 PhnG protein 4595942 phnG 3990963 phnG Escherichia coli UTI89 PhnG protein YP_543635.1 4595490 R 364106 CDS YP_543636.1 91213650 3990964 complement(4595943..4596677) 1 NC_007946.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4596677 phnF 3990964 phnF Escherichia coli UTI89 phosphonate metabolism transcriptional regulator PhnF YP_543636.1 4595943 R 364106 CDS YP_543637.1 91213651 3990965 complement(4596689..4597531) 1 NC_007946.1 PhnE subunit of alkylphosphonate ABC transporter 4597531 phnE 3990965 phnE Escherichia coli UTI89 PhnE subunit of alkylphosphonate ABC transporter YP_543637.1 4596689 R 364106 CDS YP_543638.1 91213652 3990966 complement(4597574..4598590) 1 NC_007946.1 PhnD subunit of alkylphosphonate ABC transporter 4598590 phnD 3990966 phnD Escherichia coli UTI89 PhnD subunit of alkylphosphonate ABC transporter YP_543638.1 4597574 R 364106 CDS YP_543639.1 91213653 3990967 complement(4598615..4599403) 1 NC_007946.1 phosphonate/organophosphate ester transporter subunit 4599403 phnC 3990967 phnC Escherichia coli UTI89 phosphonate/organophosphate ester transporter subunit YP_543639.1 4598615 R 364106 CDS YP_543640.1 91213654 3990968 complement(4599536..4599979) 1 NC_007946.1 hypothetical protein 4599979 phnB 3990968 phnB Escherichia coli UTI89 hypothetical protein YP_543640.1 4599536 R 364106 CDS YP_543641.1 91213655 3990969 complement(4600139..4600621) 1 NC_007946.1 hypothetical protein 4600621 phnA 3990969 phnA Escherichia coli UTI89 hypothetical protein YP_543641.1 4600139 R 364106 CDS YP_543642.1 91213656 3990970 4600877..4603105 1 NC_007946.1 hypothetical protein 4603105 yjdA 3990970 yjdA Escherichia coli UTI89 hypothetical protein YP_543642.1 4600877 D 364106 CDS YP_543643.1 91213657 3990971 4603102..4603980 1 NC_007946.1 hypothetical protein 4603980 yjcZ 3990971 yjcZ Escherichia coli UTI89 hypothetical protein YP_543643.1 4603102 D 364106 CDS YP_543644.1 91213658 3990972 4604211..4605746 1 NC_007946.1 proline/glycine betaine transporter 4605746 proP 3990972 proP Escherichia coli UTI89 proline/glycine betaine transporter YP_543644.1 4604211 D 364106 CDS YP_543645.1 91213659 3990973 complement(4605923..4607023) 1 NC_007946.1 sensor protein BasS/PmrB 4607023 basS 3990973 basS Escherichia coli UTI89 sensor protein BasS/PmrB YP_543645.1 4605923 R 364106 CDS YP_543646.1 91213660 3990974 complement(4607024..4607692) 1 NC_007946.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4607692 basR 3990974 basR Escherichia coli UTI89 DNA-binding transcriptional regulator BasR YP_543646.1 4607024 R 364106 CDS YP_543647.1 91213661 3990975 complement(4607689..4609377) 1 NC_007946.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 4609377 yjdB 3990975 yjdB Escherichia coli UTI89 cell division protein YP_543647.1 4607689 R 364106 CDS YP_543648.1 91213662 3990976 complement(4609436..4610773) 1 NC_007946.1 arginine:agmatin antiporter 4610773 yjdE 3990976 yjdE Escherichia coli UTI89 arginine:agmatin antiporter YP_543648.1 4609436 R 364106 CDS YP_543649.1 91213663 3990919 complement(4610910..4611671) 1 NC_007946.1 AdiY transcriptional regulatory protein 4611671 adiY 3990919 adiY Escherichia coli UTI89 AdiY transcriptional regulatory protein YP_543649.1 4610910 R 364106 CDS YP_543650.1 91213664 3990920 complement(4612007..4614277) 1 NC_007946.1 biodegradative arginine decarboxylase 4614277 adiA 3990920 adiA Escherichia coli UTI89 biodegradative arginine decarboxylase YP_543650.1 4612007 R 364106 CDS YP_543651.1 91213665 3990921 complement(4614473..4615381) 1 NC_007946.1 DNA-binding transcriptional regulator MelR 4615381 melR 3990921 melR Escherichia coli UTI89 DNA-binding transcriptional regulator MelR YP_543651.1 4614473 R 364106 CDS YP_543652.1 91213666 3990922 4615664..4617019 1 NC_007946.1 alpha-galactosidase 4617019 melA 3990922 melA Escherichia coli UTI89 alpha-galactosidase YP_543652.1 4615664 D 364106 CDS YP_543653.1 91213667 3990923 complement(4617016..4617666) 1 NC_007946.1 hypothetical protein 4617666 yjdF 3990923 yjdF Escherichia coli UTI89 hypothetical protein YP_543653.1 4617016 R 364106 CDS YP_543654.1 91213668 3990924 complement(4617789..4619435) 1 NC_007946.1 fumarate hydratase class I, anaerobic 4619435 fumB 3990924 fumB Escherichia coli UTI89 fumarate hydratase class I, anaerobic YP_543654.1 4617789 R 364106 CDS YP_543655.1 91213669 3990925 complement(4619513..4620853) 1 NC_007946.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4620853 dcuB 3990925 dcuB Escherichia coli UTI89 anaerobic C4-dicarboxylate transporter YP_543655.1 4619513 R 364106 CDS YP_543656.1 91213670 3990926 4620921..4621079 1 NC_007946.1 hypothetical protein 4621079 3990926 UTI89_C4717 Escherichia coli UTI89 hypothetical protein YP_543656.1 4620921 D 364106 CDS YP_543657.1 91213671 3990927 complement(4621424..4622143) 1 NC_007946.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4622143 yjdG 3990927 yjdG Escherichia coli UTI89 DNA-binding transcriptional activator DcuR YP_543657.1 4621424 R 364106 CDS YP_543658.1 91213672 3990928 complement(4622140..4623771) 1 NC_007946.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4623771 yjdH 3990928 yjdH Escherichia coli UTI89 sensory histidine kinase DcuS YP_543658.1 4622140 R 364106 CDS YP_543659.1 91213673 3990929 4623952..4624182 1 NC_007946.1 hypothetical protein 4624182 yjdI 3990929 yjdI Escherichia coli UTI89 hypothetical protein YP_543659.1 4623952 D 364106 CDS YP_543660.1 91213674 3990930 4624194..4624466 1 NC_007946.1 hypothetical protein 4624466 yjdJ 3990930 yjdJ Escherichia coli UTI89 hypothetical protein YP_543660.1 4624194 D 364106 CDS YP_543661.1 91213675 3990931 complement(4624223..4624675) 1 NC_007946.1 hypothetical protein 4624675 3990931 UTI89_C4722 Escherichia coli UTI89 hypothetical protein YP_543661.1 4624223 R 364106 CDS YP_543662.1 91213676 3990932 4624695..4624991 1 NC_007946.1 hypothetical protein 4624991 yjdK 3990932 yjdK Escherichia coli UTI89 hypothetical protein YP_543662.1 4624695 D 364106 CDS YP_543663.1 91213677 3990933 4625019..4625192 1 NC_007946.1 hypothetical protein 4625192 3990933 UTI89_C4724 Escherichia coli UTI89 hypothetical protein YP_543663.1 4625019 D 364106 CDS YP_543664.1 91213678 3990934 4625202..4625345 1 NC_007946.1 hypothetical protein 4625345 3990934 UTI89_C4725 Escherichia coli UTI89 hypothetical protein YP_543664.1 4625202 D 364106 CDS YP_543665.2 162138308 3990935 complement(4625311..4626828) 1 NC_007946.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4626828 lysU 3990935 lysU Escherichia coli UTI89 lysyl-tRNA synthetase YP_543665.2 4625311 R 364106 CDS YP_543666.1 91213680 3990936 complement(4627065..4628522) 1 NC_007946.1 transporter YjdL 4628522 yjdL 3990936 yjdL Escherichia coli UTI89 transporter YjdL YP_543666.1 4627065 R 364106 CDS YP_543667.1 91213681 3990937 complement(4628581..4630734) 1 NC_007946.1 CadA subunit of lysine decarboxylase 4630734 cadA 3990937 cadA Escherichia coli UTI89 CadA subunit of lysine decarboxylase YP_543667.1 4628581 R 364106 CDS YP_543668.1 91213682 3991032 complement(4630808..4632142) 1 NC_007946.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4632142 cadB 3991032 cadB Escherichia coli UTI89 lysine/cadaverine antiporter YP_543668.1 4630808 R 364106 CDS YP_543669.1 91213683 3991033 complement(4632508..4634046) 1 NC_007946.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4634046 cadC 3991033 cadC Escherichia coli UTI89 DNA-binding transcriptional activator CadC YP_543669.1 4632508 R 364106 CDS YP_543670.1 91213684 3991035 complement(4634845..4635444) 1 NC_007946.1 transcriptional regulator 4635444 yjdC 3991035 yjdC Escherichia coli UTI89 transcriptional regulator YP_543670.1 4634845 R 364106 CDS YP_543671.1 91213685 3991036 complement(4635457..4637154) 1 NC_007946.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4637154 dipZ 3991036 dipZ Escherichia coli UTI89 thiol:disulfide interchange protein YP_543671.1 4635457 R 364106 CDS YP_543672.2 162138307 3991037 complement(4637130..4637468) 1 NC_007946.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4637468 cutA 3991037 cutA Escherichia coli UTI89 divalent-cation tolerance protein CutA YP_543672.2 4637130 R 364106 CDS YP_543673.1 91213687 3991038 complement(4637584..4638885) 1 NC_007946.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4638885 dcuA 3991038 dcuA Escherichia coli UTI89 anaerobic C4-dicarboxylate transporter YP_543673.1 4637584 R 364106 CDS YP_543674.1 91213688 3991039 complement(4639003..4640484) 1 NC_007946.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4640484 aspA 3991039 aspA Escherichia coli UTI89 aspartate ammonia-lyase YP_543674.1 4639003 R 364106 CDS YP_543675.1 91213689 3991040 complement(4640475..4640591) 1 NC_007946.1 hypothetical protein 4640591 3991040 UTI89_C4737 Escherichia coli UTI89 hypothetical protein YP_543675.1 4640475 R 364106 CDS YP_543676.1 91213690 3991041 4640776..4641252 1 NC_007946.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4641252 fxsA 3991041 fxsA Escherichia coli UTI89 FxsA protein YP_543676.1 4640776 D 364106 CDS YP_543677.2 162138306 3991042 complement(4641268..4642524) 1 NC_007946.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 4642524 yjeH 3991042 yjeH Escherichia coli UTI89 hypothetical protein YP_543677.2 4641268 R 364106 CDS YP_543678.1 91213692 3991043 4642800..4643093 1 NC_007946.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4643093 groES 3991043 groES Escherichia coli UTI89 co-chaperonin GroES YP_543678.1 4642800 D 364106 CDS YP_543679.1 91213693 3991044 4643137..4644783 1 NC_007946.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4644783 groEL 3991044 groEL Escherichia coli UTI89 molecular chaperone GroEL YP_543679.1 4643137 D 364106 CDS YP_543680.1 91213694 3991045 4644888..4645274 1 NC_007946.1 hypothetical protein 4645274 yjeI 3991045 yjeI Escherichia coli UTI89 hypothetical protein YP_543680.1 4644888 D 364106 CDS YP_543681.1 91213695 3991046 complement(4645324..4646193) 1 NC_007946.1 hypothetical protein 4646193 yjeJ 3991046 yjeJ Escherichia coli UTI89 hypothetical protein YP_543681.1 4645324 R 364106 CDS YP_543682.1 91213696 3991047 complement(4646428..4647456) 1 NC_007946.1 hypothetical protein 4647456 yjeK 3991047 yjeK Escherichia coli UTI89 hypothetical protein YP_543682.1 4646428 R 364106 CDS YP_543683.1 91213697 3991048 4647498..4648064 1 NC_007946.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4648064 efp 3991048 efp Escherichia coli UTI89 elongation factor P YP_543683.1 4647498 D 364106 CDS YP_543684.1 91213698 3991049 4648116..4648241 1 NC_007946.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4648241 ecnA 3991049 ecnA Escherichia coli UTI89 entericidin A YP_543684.1 4648116 D 364106 CDS YP_543685.1 91213699 3991050 4648352..4648498 1 NC_007946.1 entericidin B 4648498 ecnB 3991050 ecnB Escherichia coli UTI89 entericidin B YP_543685.1 4648352 D 364106 CDS YP_543686.1 91213700 3990996 4648611..4648991 1 NC_007946.1 SugE SMR transporter 4648991 sugE 3990996 sugE Escherichia coli UTI89 SugE SMR transporter YP_543686.1 4648611 D 364106 CDS YP_543687.1 91213701 3990997 complement(4648988..4649521) 1 NC_007946.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4649521 blc 3990997 blc Escherichia coli UTI89 outer membrane lipoprotein Blc YP_543687.1 4648988 R 364106 CDS YP_543688.2 162138305 3990998 complement(4649610..4650743) 1 NC_007946.1 beta-lactamase 4650743 ampC 3990998 ampC Escherichia coli UTI89 beta-lactamase YP_543688.2 4649610 R 364106 CDS YP_543689.1 91213703 3990999 complement(4650806..4651165) 1 NC_007946.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4651165 frdD 3990999 frdD Escherichia coli UTI89 fumarate reductase subunit D YP_543689.1 4650806 R 364106 CDS YP_543690.1 91213704 3991000 complement(4651176..4651571) 1 NC_007946.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4651571 frdC 3991000 frdC Escherichia coli UTI89 fumarate reductase subunit C YP_543690.1 4651176 R 364106 CDS YP_543691.1 91213705 3991001 complement(4651582..4652316) 1 NC_007946.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4652316 frdB 3991001 frdB Escherichia coli UTI89 fumarate reductase iron-sulfur subunit YP_543691.1 4651582 R 364106 CDS YP_543692.1 91213706 3991002 complement(4652309..4654117) 1 NC_007946.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4654117 frdA 3991002 frdA Escherichia coli UTI89 fumarate reductase flavoprotein subunit YP_543692.1 4652309 R 364106 CDS YP_543693.1 91213707 3991003 4654442..4655419 1 NC_007946.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4655419 yjeA 3991003 yjeA Escherichia coli UTI89 lysyl-tRNA synthetase YP_543693.1 4654442 D 364106 CDS YP_543694.1 91213708 3991004 4655596..4657140 1 NC_007946.1 transporter YjeM 4657140 yjeM 3991004 yjeM Escherichia coli UTI89 transporter YjeM YP_543694.1 4655596 D 364106 CDS YP_543695.1 91213709 3991005 4657203..4657517 1 NC_007946.1 hypothetical protein 4657517 yjeN 3991005 yjeN Escherichia coli UTI89 hypothetical protein YP_543695.1 4657203 D 364106 CDS YP_543696.1 91213710 3991006 4657514..4657828 1 NC_007946.1 hypothetical protein 4657828 yjeO 3991006 yjeO Escherichia coli UTI89 hypothetical protein YP_543696.1 4657514 D 364106 CDS YP_543697.1 91213711 3991007 complement(4657859..4661182) 1 NC_007946.1 hypothetical protein 4661182 yjeP 3991007 yjeP Escherichia coli UTI89 hypothetical protein YP_543697.1 4657859 R 364106 CDS YP_543698.1 91213712 3991008 complement(4661204..4662172) 1 NC_007946.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4662172 psd 3991008 psd Escherichia coli UTI89 phosphatidylserine decarboxylase YP_543698.1 4661204 R 364106 CDS YP_543699.2 162138304 3991009 complement(4662269..4663321) 1 NC_007946.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4663321 yjeQ 3991009 yjeQ Escherichia coli UTI89 ribosome-associated GTPase YP_543699.2 4662269 R 364106 CDS YP_543700.1 91213714 3991010 4663299..4663961 1 NC_007946.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4663961 orn 3991010 orn Escherichia coli UTI89 oligoribonuclease YP_543700.1 4663299 D 364106 CDS YP_543701.1 91213715 3990882 complement(4664740..4665924) 1 NC_007946.1 electron transport protein YjeS 4665924 yjeS 3990882 yjeS Escherichia coli UTI89 electron transport protein YjeS YP_543701.1 4664740 R 364106 CDS YP_543702.1 91213716 3990883 4665857..4667425 1 NC_007946.1 hypothetical protein 4667425 yjeF 3990883 yjeF Escherichia coli UTI89 hypothetical protein YP_543702.1 4665857 D 364106 CDS YP_543703.1 91213717 3990884 4667397..4667858 1 NC_007946.1 possibly involved in cell wall synthesis; ATPase 4667858 yjeE 3990884 yjeE Escherichia coli UTI89 ATPase YP_543703.1 4667397 D 364106 CDS YP_543704.1 91213718 3990885 4667862..4669214 1 NC_007946.1 N-acetylmuramoyl-L-alanine amidase 4669214 amiB 3990885 amiB Escherichia coli UTI89 N-acetylmuramoyl-L-alanine amidase YP_543704.1 4667862 D 364106 CDS YP_543705.1 91213719 3990886 4669221..4671071 1 NC_007946.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4671071 mutL 3990886 mutL Escherichia coli UTI89 DNA mismatch repair protein YP_543705.1 4669221 D 364106 CDS YP_543706.1 91213720 3990887 4671064..4672014 1 NC_007946.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4672014 miaA 3990887 miaA Escherichia coli UTI89 tRNA delta(2)-isopentenylpyrophosphate transferase YP_543706.1 4671064 D 364106 CDS YP_543707.1 91213721 3990888 4672100..4672408 1 NC_007946.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4672408 hfq 3990888 hfq Escherichia coli UTI89 RNA-binding protein Hfq YP_543707.1 4672100 D 364106 CDS YP_543708.1 91213722 3990889 4672484..4673764 1 NC_007946.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4673764 hflX 3990889 hflX Escherichia coli UTI89 GTPase HflX YP_543708.1 4672484 D 364106 CDS YP_543709.1 91213723 3990890 4673850..4675109 1 NC_007946.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4675109 hflK 3990890 hflK Escherichia coli UTI89 FtsH protease regulator HflK YP_543709.1 4673850 D 364106 CDS YP_543710.1 91213724 3990891 4675112..4676116 1 NC_007946.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4676116 hflC 3990891 hflC Escherichia coli UTI89 FtsH protease regulator HflC YP_543710.1 4675112 D 364106 CDS YP_543711.1 91213725 3990892 4676198..4676395 1 NC_007946.1 hypothetical protein 4676395 3990892 UTI89_C4776 Escherichia coli UTI89 hypothetical protein YP_543711.1 4676198 D 364106 CDS YP_543712.1 91213726 3990893 4676499..4677797 1 NC_007946.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4677797 purA 3990893 purA Escherichia coli UTI89 adenylosuccinate synthetase YP_543712.1 4676499 D 364106 CDS YP_543713.1 91213727 3990894 4678002..4678427 1 NC_007946.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4678427 yjeB 3990894 yjeB Escherichia coli UTI89 transcriptional repressor NsrR YP_543713.1 4678002 D 364106 CDS YP_543714.2 162138303 3990895 4678466..4680907 1 NC_007946.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4680907 vacB 3990895 vacB Escherichia coli UTI89 exoribonuclease R YP_543714.2 4678466 D 364106 CDS YP_543715.1 91213729 3990896 4680999..4681730 1 NC_007946.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4681730 yjfH 3990896 yjfH Escherichia coli UTI89 23S rRNA (guanosine-2'-O-)-methyltransferase YP_543715.1 4680999 D 364106 CDS YP_543716.1 91213730 3990897 4681857..4682258 1 NC_007946.1 hypothetical protein 4682258 yjfI 3990897 yjfI Escherichia coli UTI89 hypothetical protein YP_543716.1 4681857 D 364106 CDS YP_543717.1 91213731 3990898 4682277..4682975 1 NC_007946.1 hypothetical protein 4682975 yjfJ 3990898 yjfJ Escherichia coli UTI89 hypothetical protein YP_543717.1 4682277 D 364106 CDS YP_543718.1 91213732 3990899 4683025..4683684 1 NC_007946.1 hypothetical protein 4683684 yjfK 3990899 yjfK Escherichia coli UTI89 hypothetical protein YP_543718.1 4683025 D 364106 CDS YP_543719.1 91213733 3989823 4683702..4684100 1 NC_007946.1 hypothetical protein 4684100 yjfL 3989823 yjfL Escherichia coli UTI89 hypothetical protein YP_543719.1 4683702 D 364106 CDS YP_543720.1 91213734 3989824 4684110..4684748 1 NC_007946.1 hypothetical protein 4684748 yjfM 3989824 yjfM Escherichia coli UTI89 hypothetical protein YP_543720.1 4684110 D 364106 CDS YP_543721.1 91213735 3989825 4684751..4685914 1 NC_007946.1 synthetase/amidase 4685914 yjfC 3989825 yjfC Escherichia coli UTI89 synthetase/amidase YP_543721.1 4684751 D 364106 CDS YP_543722.1 91213736 3989826 4685980..4687623 1 NC_007946.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4687623 aidB 3989826 aidB Escherichia coli UTI89 isovaleryl CoA dehydrogenase YP_543722.1 4685980 D 364106 CDS YP_543723.1 91213737 3989827 complement(4687740..4688042) 1 NC_007946.1 hypothetical protein 4688042 yjfN 3989827 yjfN Escherichia coli UTI89 hypothetical protein YP_543723.1 4687740 R 364106 CDS YP_543724.1 91213738 3989828 complement(4688164..4688592) 1 NC_007946.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 4688592 yjfO 3989828 yjfO Escherichia coli UTI89 biofilm stress and motility protein A YP_543724.1 4688164 R 364106 CDS YP_543725.1 91213739 3989829 4688675..4689424 1 NC_007946.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4689424 yjfP 3989829 yjfP Escherichia coli UTI89 esterase YP_543725.1 4688675 D 364106 CDS YP_543726.1 91213740 3989830 complement(4689421..4690176) 1 NC_007946.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4690176 yjfQ 3989830 yjfQ Escherichia coli UTI89 transcriptional repressor UlaR YP_543726.1 4689421 R 364106 CDS YP_543727.1 91213741 3989831 complement(4690284..4691354) 1 NC_007946.1 L-ascorbate 6-phosphate lactonase 4691354 yjfR 3989831 yjfR Escherichia coli UTI89 L-ascorbate 6-phosphate lactonase YP_543727.1 4690284 R 364106 CDS YP_543728.1 91213742 3989832 4691703..4693100 1 NC_007946.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4693100 ulaA 3989832 ulaA Escherichia coli UTI89 PTS system ascorbate-specific transporter subunit IIC YP_543728.1 4691703 D 364106 CDS YP_543729.1 91213743 3989833 4693110..4693421 1 NC_007946.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4693421 sgaB 3989833 sgaB Escherichia coli UTI89 PTS system L-ascorbate-specific transporter subunit IIB YP_543729.1 4693110 D 364106 CDS YP_543730.1 91213744 3989834 4693431..4693895 1 NC_007946.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4693895 sgaA 3989834 sgaA Escherichia coli UTI89 PTS system L-ascorbate-specific transporter subunit IIA YP_543730.1 4693431 D 364106 CDS YP_543731.2 162138302 3989835 4693909..4694559 1 NC_007946.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4694559 ulaD 3989835 ulaD Escherichia coli UTI89 3-keto-L-gulonate-6-phosphate decarboxylase YP_543731.2 4693909 D 364106 CDS YP_543732.1 91213746 3989836 4694569..4695423 1 NC_007946.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4695423 sgaU 3989836 sgaU Escherichia coli UTI89 L-xylulose 5-phosphate 3-epimerase YP_543732.1 4694569 D 364106 CDS YP_543733.2 162138301 3989837 4695423..4696109 1 NC_007946.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4696109 sgaE 3989837 sgaE Escherichia coli UTI89 L-ribulose-5-phosphate 4-epimerase YP_543733.2 4695423 D 364106 CDS YP_543734.1 91213748 3989838 complement(4696238..4696513) 1 NC_007946.1 hypothetical protein 4696513 yjfY 3989838 yjfY Escherichia coli UTI89 hypothetical protein YP_543734.1 4696238 R 364106 CDS YP_543735.1 91213749 3989839 4696841..4697236 1 NC_007946.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4697236 rpsF 3989839 rpsF Escherichia coli UTI89 30S ribosomal protein S6 YP_543735.1 4696841 D 364106 CDS YP_543736.1 91213750 3989840 4697243..4697557 1 NC_007946.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4697557 priB 3989840 priB Escherichia coli UTI89 primosomal replication protein N YP_543736.1 4697243 D 364106 CDS YP_543737.1 91213751 3989841 4697562..4697789 1 NC_007946.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4697789 rpsR 3989841 rpsR Escherichia coli UTI89 30S ribosomal protein S18 YP_543737.1 4697562 D 364106 CDS YP_543738.1 91213752 3991971 4697831..4698280 1 NC_007946.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4698280 rplI 3991971 rplI Escherichia coli UTI89 50S ribosomal protein L9 YP_543738.1 4697831 D 364106 CDS YP_543739.1 91213753 3991972 4698682..4699173 1 NC_007946.1 hypothetical protein 4699173 3991972 UTI89_C4804 Escherichia coli UTI89 hypothetical protein YP_543739.1 4698682 D 364106 CDS YP_543740.1 91213754 3991973 4699176..4700444 1 NC_007946.1 hypothetical protein 4700444 3991973 UTI89_C4805 Escherichia coli UTI89 hypothetical protein YP_543740.1 4699176 D 364106 CDS YP_543741.1 91213755 3991974 complement(4700587..4701756) 1 NC_007946.1 hexuronate transporter 4701756 3991974 UTI89_C4806 Escherichia coli UTI89 hexuronate transporter YP_543741.1 4700587 R 364106 CDS YP_543742.1 91213756 3991975 complement(4701838..4702341) 1 NC_007946.1 IS1 protein InsB 4702341 insBcp3 3991975 insBcp3 Escherichia coli UTI89 IS1 protein InsB YP_543742.1 4701838 R 364106 CDS YP_543743.1 91213757 3991976 complement(4702260..4702535) 1 NC_007946.1 IS1 protein InsA 4702535 insAcp3 3991976 insAcp3 Escherichia coli UTI89 IS1 protein InsA YP_543743.1 4702260 R 364106 CDS YP_543744.1 91213758 3991977 complement(4702734..4704806) 1 NC_007946.1 oxidoreductase 4704806 3991977 UTI89_C4809 Escherichia coli UTI89 oxidoreductase YP_543744.1 4702734 R 364106 CDS YP_543745.1 91213759 3991978 complement(4704803..4706344) 1 NC_007946.1 acetyl-CoA:acetoacetyl-CoA transferase 4706344 3991978 UTI89_C4810 Escherichia coli UTI89 acetyl-CoA:acetoacetyl-CoA transferase YP_543745.1 4704803 R 364106 CDS YP_543746.1 91213760 3991979 complement(4706354..4707130) 1 NC_007946.1 hypothetical protein 4707130 3991979 UTI89_C4811 Escherichia coli UTI89 hypothetical protein YP_543746.1 4706354 R 364106 CDS YP_543747.1 91213761 3991980 complement(4707133..4707981) 1 NC_007946.1 hypothetical protein 4707981 3991980 UTI89_C4812 Escherichia coli UTI89 hypothetical protein YP_543747.1 4707133 R 364106 CDS YP_543748.1 91213762 3991981 complement(4707991..4708782) 1 NC_007946.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4708782 3991981 UTI89_C4813 Escherichia coli UTI89 3-ketoacyl-ACP reductase YP_543748.1 4707991 R 364106 CDS YP_543749.1 91213763 3991982 4708922..4709641 1 NC_007946.1 hypothetical protein 4709641 3991982 UTI89_C4814 Escherichia coli UTI89 hypothetical protein YP_543749.1 4708922 D 364106 CDS YP_543750.1 91213764 3991983 complement(4709625..4710299) 1 NC_007946.1 hypothetical protein 4710299 ytfB 3991983 ytfB Escherichia coli UTI89 hypothetical protein YP_543750.1 4709625 R 364106 CDS YP_543751.2 162138300 3991984 4710481..4711101 1 NC_007946.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4711101 fklB 3991984 fklB Escherichia coli UTI89 peptidyl-prolyl cis-trans isomerase YP_543751.2 4710481 D 364106 CDS YP_543752.1 91213766 3991985 4711410..4712822 1 NC_007946.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4712822 cycA 3991985 cycA Escherichia coli UTI89 D-alanine/D-serine/glycine permease YP_543752.1 4711410 D 364106 CDS YP_543753.1 91213767 3991986 complement(4712867..4713529) 1 NC_007946.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4713529 ytfE 3991986 ytfE Escherichia coli UTI89 iron-sulfur cluster repair di-iron protein YP_543753.1 4712867 R 364106 CDS YP_543754.1 91213768 3991987 complement(4713637..4714611) 1 NC_007946.1 hypothetical protein 4714611 ytfF 3991987 ytfF Escherichia coli UTI89 hypothetical protein YP_543754.1 4713637 R 364106 CDS YP_543755.1 91213769 3991988 complement(4714710..4715570) 1 NC_007946.1 hypothetical protein 4715570 ytfG 3991988 ytfG Escherichia coli UTI89 hypothetical protein YP_543755.1 4714710 R 364106 CDS YP_543756.1 91213770 3991989 4715548..4716039 1 NC_007946.1 hypothetical protein 4716039 ytfH 3991989 ytfH Escherichia coli UTI89 hypothetical protein YP_543756.1 4715548 D 364106 CDS YP_543757.1 91213771 3991990 complement(4716168..4718111) 1 NC_007946.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4718111 cpdB 3991990 cpdB Escherichia coli UTI89 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_543757.1 4716168 R 364106 CDS YP_543758.1 91213772 3991991 4718301..4719041 1 NC_007946.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4719041 cysQ 3991991 cysQ Escherichia coli UTI89 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_543758.1 4718301 D 364106 CDS YP_543759.1 91213773 3991992 complement(4719031..4719588) 1 NC_007946.1 hypothetical protein 4719588 ytfJ 3991992 ytfJ Escherichia coli UTI89 hypothetical protein YP_543759.1 4719031 R 364106 CDS YP_543760.1 91213774 3991993 4719847..4720119 1 NC_007946.1 hypothetical protein 4720119 ytfK 3991993 ytfK Escherichia coli UTI89 hypothetical protein YP_543760.1 4719847 D 364106 CDS YP_543761.1 91213775 3991994 complement(4720197..4721540) 1 NC_007946.1 transport protein 4721540 ytfL 3991994 ytfL Escherichia coli UTI89 transport protein YP_543761.1 4720197 R 364106 CDS YP_543762.1 91213776 3991995 complement(4721863..4722567) 1 NC_007946.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4722567 msrA 3991995 msrA Escherichia coli UTI89 methionine sulfoxide reductase A YP_543762.1 4721863 R 364106 CDS YP_543763.1 91213777 3991996 4722707..4724440 1 NC_007946.1 hypothetical protein 4724440 ytfM 3991996 ytfM Escherichia coli UTI89 hypothetical protein YP_543763.1 4722707 D 364106 CDS YP_543764.1 91213778 3991997 4724437..4728216 1 NC_007946.1 hypothetical protein 4728216 ytfN 3991997 ytfN Escherichia coli UTI89 hypothetical protein YP_543764.1 4724437 D 364106 CDS YP_543765.1 91213779 3991998 4728219..4728560 1 NC_007946.1 hypothetical protein 4728560 ytfP 3991998 ytfP Escherichia coli UTI89 hypothetical protein YP_543765.1 4728219 D 364106 CDS YP_543766.1 91213780 3991999 complement(4728940..4729470) 1 NC_007946.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4729470 ppa 3991999 ppa Escherichia coli UTI89 inorganic pyrophosphatase YP_543766.1 4728940 R 364106 CDS YP_543767.1 91213781 3992000 4729780..4730736 1 NC_007946.1 LACI-type transcriptional regulator 4730736 ytfQ 3992000 ytfQ Escherichia coli UTI89 LACI-type transcriptional regulator YP_543767.1 4729780 D 364106 CDS YP_543768.1 91213782 3992001 4730876..4732378 1 NC_007946.1 ATP-binding protein of a transport system 4732378 ytfR 3992001 ytfR Escherichia coli UTI89 ATP-binding protein of a transport system YP_543768.1 4730876 D 364106 CDS YP_543769.1 91213783 3992002 4732368..4733414 1 NC_007946.1 ABC transporter permease 4733414 ytfT 3992002 ytfT Escherichia coli UTI89 ABC transporter permease YP_543769.1 4732368 D 364106 CDS YP_543770.1 91213784 3992003 4733401..4734396 1 NC_007946.1 membrane component of a sugar ABC transporter system; ABC transporter permease 4734396 yjfF 3992003 yjfF Escherichia coli UTI89 ABC transporter permease YP_543770.1 4733401 D 364106 CDS YP_543771.1 91213785 3992004 complement(4734429..4735490) 1 NC_007946.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4735490 fbp 3992004 fbp Escherichia coli UTI89 fructose-1,6-bisphosphatase YP_543771.1 4734429 R 364106 CDS YP_543772.1 91213786 3992005 4735603..4736976 1 NC_007946.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4736976 yjfG 3992005 yjfG Escherichia coli UTI89 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_543772.1 4735603 D 364106 CDS YP_543773.1 91213787 3992006 complement(4737134..4737685) 1 NC_007946.1 hypothetical protein 4737685 yjgA 3992006 yjgA Escherichia coli UTI89 hypothetical protein YP_543773.1 4737134 R 364106 CDS YP_543774.1 91213788 3992007 4737779..4739131 1 NC_007946.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4739131 pmbA 3992007 pmbA Escherichia coli UTI89 peptidase PmbA YP_543774.1 4737779 D 364106 CDS YP_543775.1 91213789 3992008 4739315..4739701 1 NC_007946.1 soluble cytochrome b562 4739701 cybC 3992008 cybC Escherichia coli UTI89 soluble cytochrome b562 YP_543775.1 4739315 D 364106 CDS YP_543776.1 91213790 3992009 complement(4739746..4740210) 1 NC_007946.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4740210 nrdG 3992009 nrdG Escherichia coli UTI89 anaerobic ribonucleotide reductase-activating protein YP_543776.1 4739746 R 364106 CDS YP_543777.1 91213791 3992049 complement(4740368..4742506) 1 NC_007946.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4742506 nrdD 3992049 nrdD Escherichia coli UTI89 anaerobic ribonucleoside triphosphate reductase YP_543777.1 4740368 R 364106 CDS YP_543778.1 91213792 3992050 complement(4742900..4744555) 1 NC_007946.1 trehalose-6-phosphate hydrolase 4744555 treC 3992050 treC Escherichia coli UTI89 trehalose-6-phosphate hydrolase YP_543778.1 4742900 R 364106 CDS YP_543779.1 91213793 3992051 complement(4744605..4746026) 1 NC_007946.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 4746026 treB 3992051 treB Escherichia coli UTI89 PTS system trehalose(maltose)-specific transporter subunits IIBC YP_543779.1 4744605 R 364106 CDS YP_543780.1 91213794 3992052 complement(4746145..4747092) 1 NC_007946.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4747092 treR 3992052 treR Escherichia coli UTI89 trehalose repressor YP_543780.1 4746145 R 364106 CDS YP_543781.1 91213795 3992053 4747142..4747330 1 NC_007946.1 hypothetical protein 4747330 3992053 UTI89_C4846 Escherichia coli UTI89 hypothetical protein YP_543781.1 4747142 D 364106 CDS YP_543782.1 91213796 3992054 4747471..4750167 1 NC_007946.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4750167 mgtA 3992054 mgtA Escherichia coli UTI89 magnesium-transporting ATPase MgtA YP_543782.1 4747471 D 364106 CDS YP_543783.1 91213797 3992055 complement(4750373..4750831) 1 NC_007946.1 hypothetical protein 4750831 yjgF 3992055 yjgF Escherichia coli UTI89 hypothetical protein YP_543783.1 4750373 R 364106 CDS YP_543784.1 91213798 3992056 4750466..4750930 1 NC_007946.1 hypothetical protein 4750930 3992056 UTI89_C4849 Escherichia coli UTI89 hypothetical protein YP_543784.1 4750466 D 364106 CDS YP_543785.1 91213799 3992057 complement(4750832..4751293) 1 NC_007946.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 4751293 pyrI 3992057 pyrI Escherichia coli UTI89 aspartate carbamoyltransferase YP_543785.1 4750832 R 364106 CDS YP_543786.1 91213800 3992058 complement(4751306..4752241) 1 NC_007946.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 4752241 pyrB 3992058 pyrB Escherichia coli UTI89 aspartate carbamoyltransferase YP_543786.1 4751306 R 364106 CDS YP_543787.1 91213801 3992059 complement(4752245..4752379) 1 NC_007946.1 pyrBI operon leader peptide 4752379 pyrL 3992059 pyrL Escherichia coli UTI89 pyrBI operon leader peptide YP_543787.1 4752245 R 364106 CDS YP_543788.1 91213802 3992060 complement(4752469..4753023) 1 NC_007946.1 hypothetical protein 4753023 3992060 UTI89_C4853 Escherichia coli UTI89 hypothetical protein YP_543788.1 4752469 R 364106 CDS YP_543789.1 91213803 3992061 complement(4753073..4754521) 1 NC_007946.1 hypothetical protein 4754521 3992061 UTI89_C4854 Escherichia coli UTI89 hypothetical protein YP_543789.1 4753073 R 364106 CDS YP_543790.1 91213804 3992062 complement(4754533..4755564) 1 NC_007946.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 4755564 argF 3992062 argF Escherichia coli UTI89 ornithine carbamoyltransferase YP_543790.1 4754533 R 364106 CDS YP_543791.1 91213805 3992063 complement(4755548..4756492) 1 NC_007946.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4756492 3992063 UTI89_C4856 Escherichia coli UTI89 carbamate kinase YP_543791.1 4755548 R 364106 CDS YP_543792.1 91213806 3992064 complement(4756503..4757723) 1 NC_007946.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 4757723 3992064 UTI89_C4857 Escherichia coli UTI89 arginine deiminase YP_543792.1 4756503 R 364106 CDS YP_543793.1 91213807 3992065 complement(4757811..4757945) 1 NC_007946.1 hypothetical protein 4757945 3992065 UTI89_C4858 Escherichia coli UTI89 hypothetical protein YP_543793.1 4757811 R 364106 CDS YP_543794.1 91213808 3992066 4758401..4758853 1 NC_007946.1 hypothetical protein 4758853 yjgK 3992066 yjgK Escherichia coli UTI89 hypothetical protein YP_543794.1 4758401 D 364106 CDS YP_543795.1 91213809 3992067 complement(4758899..4759903) 1 NC_007946.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III; ornithine carbamoyltransferase subunit F 4759903 argI 3992067 argI Escherichia coli UTI89 ornithine carbamoyltransferase subunit F YP_543795.1 4758899 R 364106 CDS YP_543796.1 91213810 3992068 4760065..4760481 1 NC_007946.1 hypothetical protein 4760481 yjgD 3992068 yjgD Escherichia coli UTI89 hypothetical protein YP_543796.1 4760065 D 364106 CDS YP_543797.1 91213811 3991147 complement(4760658..4761179) 1 NC_007946.1 hypothetical protein 4761179 3991147 UTI89_C4862 Escherichia coli UTI89 hypothetical protein YP_543797.1 4760658 R 364106 CDS YP_543798.1 91213812 3991148 4761354..4762541 1 NC_007946.1 hypothetical protein 4762541 yjgN 3991148 yjgN Escherichia coli UTI89 hypothetical protein YP_543798.1 4761354 D 364106 CDS YP_543799.1 91213813 3991149 complement(4762588..4765443) 1 NC_007946.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4765443 valS 3991149 valS Escherichia coli UTI89 valyl-tRNA synthetase YP_543799.1 4762588 R 364106 CDS YP_543800.1 91213814 3991150 complement(4765443..4765886) 1 NC_007946.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4765886 holC 3991150 holC Escherichia coli UTI89 DNA polymerase III subunit chi YP_543800.1 4765443 R 364106 CDS YP_543801.1 91213815 3991151 complement(4766144..4767655) 1 NC_007946.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4767655 pepA 3991151 pepA Escherichia coli UTI89 leucyl aminopeptidase YP_543801.1 4766144 R 364106 CDS YP_543802.1 91213816 3991152 complement(4767880..4768008) 1 NC_007946.1 hypothetical protein 4768008 3991152 UTI89_C4867 Escherichia coli UTI89 hypothetical protein YP_543802.1 4767880 R 364106 CDS YP_543803.1 91213817 3991153 4767922..4769022 1 NC_007946.1 hypothetical protein 4769022 yjgP 3991153 yjgP Escherichia coli UTI89 hypothetical protein YP_543803.1 4767922 D 364106 CDS YP_543804.1 91213818 3991154 4769019..4770104 1 NC_007946.1 hypothetical protein 4770104 yjgQ 3991154 yjgQ Escherichia coli UTI89 hypothetical protein YP_543804.1 4769019 D 364106 CDS YP_543805.1 91213819 3991155 complement(4770265..4771767) 1 NC_007946.1 hypothetical protein 4771767 yjgR 3991155 yjgR Escherichia coli UTI89 hypothetical protein YP_543805.1 4770265 R 364106 CDS YP_543806.1 91213820 3991156 complement(4771845..4772873) 1 NC_007946.1 L-idonate regulatory protein 4772873 idnR 3991156 idnR Escherichia coli UTI89 L-idonate regulatory protein YP_543806.1 4771845 R 364106 CDS YP_543807.1 91213821 3991157 complement(4772910..4774229) 1 NC_007946.1 IdnT L-idonate Gnt transporter 4774229 idnT 3991157 idnT Escherichia coli UTI89 IdnT L-idonate Gnt transporter YP_543807.1 4772910 R 364106 CDS YP_543808.1 91213822 3991158 complement(4774294..4775058) 1 NC_007946.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 4775058 idnO 3991158 idnO Escherichia coli UTI89 gluconate 5-dehydrogenase YP_543808.1 4774294 R 364106 CDS YP_543809.1 91213823 3991159 complement(4775082..4776113) 1 NC_007946.1 NAD-binding; L-idonate 5-dehydrogenase 4776113 idnD 3991159 idnD Escherichia coli UTI89 L-idonate 5-dehydrogenase YP_543809.1 4775082 R 364106 CDS YP_543810.1 91213824 3991160 4776330..4776893 1 NC_007946.1 D-gluconate kinase 4776893 idnK 3991160 idnK Escherichia coli UTI89 D-gluconate kinase YP_543810.1 4776330 D 364106 CDS YP_543811.1 91213825 3991161 complement(4776897..4777958) 1 NC_007946.1 oxidoreductase 4777958 yjgB 3991161 yjgB Escherichia coli UTI89 oxidoreductase YP_543811.1 4776897 R 364106 CDS YP_543812.1 91213826 3991163 4778383..4779645 1 NC_007946.1 prophage P4 integrase 4779645 intB 3991163 intB Escherichia coli UTI89 prophage P4 integrase YP_543812.1 4778383 D 364106 CDS YP_543813.1 91213827 3991164 complement(4779745..4780008) 1 NC_007946.1 hypothetical protein 4780008 3991164 UTI89_C4879 Escherichia coli UTI89 hypothetical protein YP_543813.1 4779745 R 364106 CDS YP_543814.1 91213828 3992029 4780097..4783612 1 NC_007946.1 DNA helicase superfamily protein I 4783612 3992029 UTI89_C4880 Escherichia coli UTI89 DNA helicase superfamily protein I YP_543814.1 4780097 D 364106 CDS YP_543815.1 91213829 3992030 complement(4783721..4784908) 1 NC_007946.1 hypothetical protein 4784908 yjgX 3992030 yjgX Escherichia coli UTI89 hypothetical protein YP_543815.1 4783721 R 364106 CDS YP_543816.1 91213830 3992031 complement(4785401..4786156) 1 NC_007946.1 adhesin 4786156 hek 3992031 hek Escherichia coli UTI89 adhesin YP_543816.1 4785401 R 364106 CDS YP_543817.1 91213831 3992032 complement(4786359..4786727) 1 NC_007946.1 hypothetical protein 4786727 3992032 UTI89_C4883 Escherichia coli UTI89 hypothetical protein YP_543817.1 4786359 R 364106 CDS YP_543818.1 91213832 3992033 4787205..4787342 1 NC_007946.1 hypothetical protein 4787342 3992033 UTI89_C4884 Escherichia coli UTI89 hypothetical protein YP_543818.1 4787205 D 364106 CDS YP_543819.1 91213833 3992034 4787503..4787802 1 NC_007946.1 hypothetical protein 4787802 3992034 UTI89_C4885 Escherichia coli UTI89 hypothetical protein YP_543819.1 4787503 D 364106 CDS YP_543820.1 91213834 3992035 complement(4788287..4788838) 1 NC_007946.1 regulator PapX protein 4788838 papX 3992035 papX Escherichia coli UTI89 regulator PapX protein YP_543820.1 4788287 R 364106 CDS YP_543821.1 91213835 3992036 complement(4789101..4790108) 1 NC_007946.1 p pilus adhesin PapG protein 4790108 papG 3992036 papG Escherichia coli UTI89 p pilus adhesin PapG protein YP_543821.1 4789101 R 364106 CDS YP_543822.1 91213836 3992037 complement(4790152..4790655) 1 NC_007946.1 minor pilin subunit PapF 4790655 papF 3992037 papF Escherichia coli UTI89 minor pilin subunit PapF YP_543822.1 4790152 R 364106 CDS YP_543823.1 91213837 3992038 complement(4790731..4791252) 1 NC_007946.1 minor pilin subunit PapE 4791252 papE 3992038 papE Escherichia coli UTI89 minor pilin subunit PapE YP_543823.1 4790731 R 364106 CDS YP_543824.1 91213838 3992039 complement(4791279..4791815) 1 NC_007946.1 minor pilin subunit PapK 4791815 papK 3992039 papK Escherichia coli UTI89 minor pilin subunit PapK YP_543824.1 4791279 R 364106 CDS YP_543825.1 91213839 3992040 complement(4791825..4792406) 1 NC_007946.1 PapJ protein 4792406 papJ 3992040 papJ Escherichia coli UTI89 PapJ protein YP_543825.1 4791825 R 364106 CDS YP_543826.1 91213840 3992041 complement(4792443..4793162) 1 NC_007946.1 periplasmid chaperone PapD protein 4793162 papD 3992041 papD Escherichia coli UTI89 periplasmid chaperone PapD protein YP_543826.1 4792443 R 364106 CDS YP_543827.1 91213841 3992042 complement(4793248..4795758) 1 NC_007946.1 outer membrane usher protein PapC 4795758 papC 3992042 papC Escherichia coli UTI89 outer membrane usher protein PapC YP_543827.1 4793248 R 364106 CDS YP_543828.1 91213842 3992043 complement(4795817..4796404) 1 NC_007946.1 minor pilin subunit PapH 4796404 papH 3992043 papH Escherichia coli UTI89 minor pilin subunit PapH YP_543828.1 4795817 R 364106 CDS YP_543829.1 91213843 3992044 complement(4796467..4797030) 1 NC_007946.1 major pilin subunit PapA 4797030 papA 3992044 papA Escherichia coli UTI89 major pilin subunit PapA YP_543829.1 4796467 R 364106 CDS YP_543830.1 91213844 3992045 complement(4797238..4797552) 1 NC_007946.1 pap operon regulatory protein PapB 4797552 papB 3992045 papB Escherichia coli UTI89 pap operon regulatory protein PapB YP_543830.1 4797238 R 364106 CDS YP_543831.1 91213845 3992046 4797957..4798190 1 NC_007946.1 pap operon regulatory protein PapI 4798190 papI 3992046 papI Escherichia coli UTI89 pap operon regulatory protein PapI YP_543831.1 4797957 D 364106 CDS YP_543832.1 91213846 3992047 4798256..4798543 1 NC_007946.1 hypothetical protein 4798543 3992047 UTI89_C4898 Escherichia coli UTI89 hypothetical protein YP_543832.1 4798256 D 364106 CDS YP_543833.1 91213847 3992048 4798693..4799061 1 NC_007946.1 hypothetical protein 4799061 3992048 UTI89_C4899 Escherichia coli UTI89 hypothetical protein YP_543833.1 4798693 D 364106 CDS YP_543834.1 91213848 3991184 complement(4800111..4800587) 1 NC_007946.1 hypothetical protein 4800587 3991184 UTI89_C4900 Escherichia coli UTI89 hypothetical protein YP_543834.1 4800111 R 364106 CDS YP_543835.1 91213849 3991185 complement(4800650..4800856) 1 NC_007946.1 hypothetical protein 4800856 3991185 UTI89_C4901 Escherichia coli UTI89 hypothetical protein YP_543835.1 4800650 R 364106 CDS YP_543836.1 91213850 3991186 complement(4801149..4801307) 1 NC_007946.1 hypothetical protein 4801307 3991186 UTI89_C4902 Escherichia coli UTI89 hypothetical protein YP_543836.1 4801149 R 364106 CDS YP_543837.1 91213851 3991187 complement(4801308..4801676) 1 NC_007946.1 hypothetical protein 4801676 3991187 UTI89_C4903 Escherichia coli UTI89 hypothetical protein YP_543837.1 4801308 R 364106 CDS YP_543838.1 91213852 3991188 complement(4801952..4803031) 1 NC_007946.1 F17-like fimbril adhesin subunit 4803031 3991188 UTI89_C4904 Escherichia coli UTI89 F17-like fimbril adhesin subunit YP_543838.1 4801952 R 364106 CDS YP_543839.1 91213853 3991189 complement(4803028..4805613) 1 NC_007946.1 F17-like fimbrial usher 4805613 3991189 UTI89_C4905 Escherichia coli UTI89 F17-like fimbrial usher YP_543839.1 4803028 R 364106 CDS YP_543840.1 91213854 3991190 complement(4805570..4806295) 1 NC_007946.1 F17-like fimbrial chaperone 4806295 3991190 UTI89_C4906 Escherichia coli UTI89 F17-like fimbrial chaperone YP_543840.1 4805570 R 364106 CDS YP_543841.1 91213855 3991191 complement(4806360..4806908) 1 NC_007946.1 F17-like fimbrial subunit 4806908 3991191 UTI89_C4907 Escherichia coli UTI89 F17-like fimbrial subunit YP_543841.1 4806360 R 364106 CDS YP_543842.1 91213856 3991192 complement(4807484..4807882) 1 NC_007946.1 hypothetical protein 4807882 3991192 UTI89_C4908 Escherichia coli UTI89 hypothetical protein YP_543842.1 4807484 R 364106 CDS YP_543843.1 91213857 3991193 complement(4807909..4809126) 1 NC_007946.1 FMN-dependent dehydrogenase 4809126 3991193 UTI89_C4909 Escherichia coli UTI89 FMN-dependent dehydrogenase YP_543843.1 4807909 R 364106 CDS YP_543844.1 91213858 3991194 complement(4809177..4809560) 1 NC_007946.1 hypothetical protein 4809560 3991194 UTI89_C4910 Escherichia coli UTI89 hypothetical protein YP_543844.1 4809177 R 364106 CDS YP_543845.1 91213859 3991195 4809697..4810536 1 NC_007946.1 UidR transriptional regulator 4810536 3991195 UTI89_C4911 Escherichia coli UTI89 UidR transriptional regulator YP_543845.1 4809697 D 364106 CDS YP_543846.1 91213860 3991196 4810505..4810828 1 NC_007946.1 hypothetical protein 4810828 3991196 UTI89_C4912 Escherichia coli UTI89 hypothetical protein YP_543846.1 4810505 D 364106 CDS YP_543847.1 91213861 3991197 complement(4811392..4811577) 1 NC_007946.1 hypothetical protein 4811577 3991197 UTI89_C4913 Escherichia coli UTI89 hypothetical protein YP_543847.1 4811392 R 364106 CDS YP_543848.1 91213862 3991198 4811641..4812774 1 NC_007946.1 hypothetical protein 4812774 3991198 UTI89_C4914 Escherichia coli UTI89 hypothetical protein YP_543848.1 4811641 D 364106 CDS YP_543849.1 91213863 3991199 complement(4812884..4814452) 1 NC_007946.1 hypothetical protein 4814452 3991199 UTI89_C4915 Escherichia coli UTI89 hypothetical protein YP_543849.1 4812884 R 364106 CDS YP_543850.1 91213864 3991200 complement(4814483..4814833) 1 NC_007946.1 hypothetical protein 4814833 3991200 UTI89_C4916 Escherichia coli UTI89 hypothetical protein YP_543850.1 4814483 R 364106 CDS YP_543851.1 91213865 3991201 complement(4814830..4815192) 1 NC_007946.1 hypothetical protein 4815192 3991201 UTI89_C4917 Escherichia coli UTI89 hypothetical protein YP_543851.1 4814830 R 364106 CDS YP_543852.1 91213866 3991202 complement(4816164..4816463) 1 NC_007946.1 hypothetical protein 4816463 3991202 UTI89_C4918 Escherichia coli UTI89 hypothetical protein YP_543852.1 4816164 R 364106 CDS YP_543853.1 91213867 3990768 4816557..4817009 1 NC_007946.1 transposase 4817009 3990768 UTI89_C4919 Escherichia coli UTI89 transposase YP_543853.1 4816557 D 364106 CDS YP_543854.1 91213868 3990769 complement(4817050..4817316) 1 NC_007946.1 hypothetical protein 4817316 3990769 UTI89_C4920 Escherichia coli UTI89 hypothetical protein YP_543854.1 4817050 R 364106 CDS YP_543855.1 91213869 3990770 complement(4817383..4820427) 1 NC_007946.1 cytotoxic necrotizing factor 1 4820427 cnf1 3990770 cnf1 Escherichia coli UTI89 cytotoxic necrotizing factor 1 YP_543855.1 4817383 R 364106 CDS YP_543856.1 91213870 3990771 complement(4820705..4820983) 1 NC_007946.1 hypothetical protein 4820983 3990771 UTI89_C4922 Escherichia coli UTI89 hypothetical protein YP_543856.1 4820705 R 364106 CDS YP_543857.1 91213871 3990772 4821053..4821334 1 NC_007946.1 hypothetical protein 4821334 3990772 UTI89_C4923 Escherichia coli UTI89 hypothetical protein YP_543857.1 4821053 D 364106 CDS YP_543858.1 91213872 3990773 complement(4821373..4822809) 1 NC_007946.1 hemolysin D 4822809 hlyD 3990773 hlyD Escherichia coli UTI89 hemolysin D YP_543858.1 4821373 R 364106 CDS YP_543859.1 91213873 3990774 complement(4822828..4824951) 1 NC_007946.1 hemolysin secretion protein HlyB 4824951 hlyB 3990774 hlyB Escherichia coli UTI89 hemolysin secretion protein HlyB YP_543859.1 4822828 R 364106 CDS YP_543860.1 91213874 3990775 complement(4825022..4828096) 1 NC_007946.1 hemolysin A 4828096 hlyA 3990775 hlyA Escherichia coli UTI89 hemolysin A YP_543860.1 4825022 R 364106 CDS YP_543861.1 91213875 3990776 complement(4828108..4828752) 1 NC_007946.1 hemolysin C 4828752 hlyC 3990776 hlyC Escherichia coli UTI89 hemolysin C YP_543861.1 4828108 R 364106 CDS YP_543862.1 91213876 3990777 complement(4829804..4830046) 1 NC_007946.1 hypothetical protein 4830046 3990777 UTI89_C4928 Escherichia coli UTI89 hypothetical protein YP_543862.1 4829804 R 364106 CDS YP_543863.1 91213877 3990778 complement(4830074..4830937) 1 NC_007946.1 hypothetical protein 4830937 3990778 UTI89_C4929 Escherichia coli UTI89 hypothetical protein YP_543863.1 4830074 R 364106 CDS YP_543864.1 91213878 3990779 complement(4830844..4831443) 1 NC_007946.1 hypothetical protein 4831443 3990779 UTI89_C4930 Escherichia coli UTI89 hypothetical protein YP_543864.1 4830844 R 364106 CDS YP_543865.1 91213879 3990780 4831580..4832302 1 NC_007946.1 response regulator 4832302 3990780 UTI89_C4931 Escherichia coli UTI89 response regulator YP_543865.1 4831580 D 364106 CDS YP_543866.1 91213880 3990781 4832303..4833775 1 NC_007946.1 hypothetical protein 4833775 3990781 UTI89_C4932 Escherichia coli UTI89 hypothetical protein YP_543866.1 4832303 D 364106 CDS YP_543867.1 91213881 3990782 complement(4833855..4834208) 1 NC_007946.1 hypothetical protein 4834208 3990782 UTI89_C4933 Escherichia coli UTI89 hypothetical protein YP_543867.1 4833855 R 364106 CDS YP_543868.1 91213882 3990783 complement(4834704..4835024) 1 NC_007946.1 hypothetical protein 4835024 3990783 UTI89_C4934 Escherichia coli UTI89 hypothetical protein YP_543868.1 4834704 R 364106 CDS YP_543869.1 91213883 3990784 complement(4835399..4835668) 1 NC_007946.1 hypothetical protein 4835668 3990784 UTI89_C4935 Escherichia coli UTI89 hypothetical protein YP_543869.1 4835399 R 364106 CDS YP_543870.1 91213884 3990785 complement(4836000..4837667) 1 NC_007946.1 hypothetical protein 4837667 3990785 UTI89_C4936 Escherichia coli UTI89 hypothetical protein YP_543870.1 4836000 R 364106 CDS YP_543871.1 91213885 3990786 complement(4837681..4840641) 1 NC_007946.1 hypothetical protein 4840641 3990786 UTI89_C4937 Escherichia coli UTI89 hypothetical protein YP_543871.1 4837681 R 364106 CDS YP_543872.1 91213886 3990787 complement(4840646..4841692) 1 NC_007946.1 hypothetical protein 4841692 3990787 UTI89_C4938 Escherichia coli UTI89 hypothetical protein YP_543872.1 4840646 R 364106 CDS YP_543873.1 91213887 3990827 complement(4841778..4842023) 1 NC_007946.1 hypothetical protein 4842023 3990827 UTI89_C4939 Escherichia coli UTI89 hypothetical protein YP_543873.1 4841778 R 364106 CDS YP_543874.1 91213888 3990828 complement(4842073..4842429) 1 NC_007946.1 hypothetical protein 4842429 3990828 UTI89_C4940 Escherichia coli UTI89 hypothetical protein YP_543874.1 4842073 R 364106 CDS YP_543875.1 91213889 3990829 complement(4842439..4842870) 1 NC_007946.1 hypothetical protein 4842870 3990829 UTI89_C4941 Escherichia coli UTI89 hypothetical protein YP_543875.1 4842439 R 364106 CDS YP_543876.1 91213890 3990830 complement(4842950..4843285) 1 NC_007946.1 hypothetical protein 4843285 3990830 UTI89_C4942 Escherichia coli UTI89 hypothetical protein YP_543876.1 4842950 R 364106 CDS YP_543877.1 91213891 3990831 complement(4843275..4843538) 1 NC_007946.1 hypothetical protein 4843538 3990831 UTI89_C4943 Escherichia coli UTI89 hypothetical protein YP_543877.1 4843275 R 364106 CDS YP_543878.1 91213892 3990832 complement(4843587..4843910) 1 NC_007946.1 hypothetical protein 4843910 3990832 UTI89_C4944 Escherichia coli UTI89 hypothetical protein YP_543878.1 4843587 R 364106 CDS YP_543879.1 91213893 3990833 complement(4843995..4844381) 1 NC_007946.1 hypothetical protein 4844381 3990833 UTI89_C4945 Escherichia coli UTI89 hypothetical protein YP_543879.1 4843995 R 364106 CDS YP_543880.1 91213894 3990834 complement(4844378..4854166) 1 NC_007946.1 ShlA/HecA/FhaA exofamily protein 4854166 3990834 UTI89_C4946 Escherichia coli UTI89 ShlA/HecA/FhaA exofamily protein YP_543880.1 4844378 R 364106 CDS YP_543881.1 91213895 3990835 complement(4854179..4855945) 1 NC_007946.1 hypothetical protein 4855945 3990835 UTI89_C4947 Escherichia coli UTI89 hypothetical protein YP_543881.1 4854179 R 364106 CDS YP_543882.1 91213896 3990836 complement(4856309..4856542) 1 NC_007946.1 hypothetical protein 4856542 3990836 UTI89_C4948 Escherichia coli UTI89 hypothetical protein YP_543882.1 4856309 R 364106 CDS YP_543883.1 91213897 3990837 complement(4856640..4857299) 1 NC_007946.1 hypothetical protein 4857299 3990837 UTI89_C4949 Escherichia coli UTI89 hypothetical protein YP_543883.1 4856640 R 364106 CDS YP_543884.1 91213898 3990838 complement(4857531..4858079) 1 NC_007946.1 hypothetical protein 4858079 3990838 UTI89_C4950 Escherichia coli UTI89 hypothetical protein YP_543884.1 4857531 R 364106 CDS YP_543886.1 91213900 3990840 complement(4858346..4858579) 1 NC_007946.1 hypothetical protein 4858579 3990840 UTI89_C4952 Escherichia coli UTI89 hypothetical protein YP_543886.1 4858346 R 364106 CDS YP_543887.1 91213901 3990841 complement(4858648..4859340) 1 NC_007946.1 hypothetical protein 4859340 3990841 UTI89_C4953 Escherichia coli UTI89 hypothetical protein YP_543887.1 4858648 R 364106 CDS YP_543888.1 91213902 3990842 complement(4859455..4860021) 1 NC_007946.1 hypothetical protein 4860021 3990842 UTI89_C4954 Escherichia coli UTI89 hypothetical protein YP_543888.1 4859455 R 364106 CDS YP_543889.1 91213903 3990843 complement(4861132..4862460) 1 NC_007946.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 4862460 3990843 UTI89_C4955 Escherichia coli UTI89 D-serine dehydratase YP_543889.1 4861132 R 364106 CDS YP_543890.1 91213904 3990844 complement(4862478..4863815) 1 NC_007946.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 4863815 3990844 UTI89_C4956 Escherichia coli UTI89 permease DsdX YP_543890.1 4862478 R 364106 CDS YP_543891.1 91213905 3990845 4864027..4864977 1 NC_007946.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 4864977 3990845 UTI89_C4957 Escherichia coli UTI89 DNA-binding transcriptional regulator DsdC YP_543891.1 4864027 D 364106 CDS YP_543892.1 91213906 3990690 complement(4865649..4865978) 1 NC_007946.1 hypothetical protein 4865978 3990690 UTI89_C4958 Escherichia coli UTI89 hypothetical protein YP_543892.1 4865649 R 364106 CDS YP_543893.1 91213907 3990691 complement(4865994..4866395) 1 NC_007946.1 hypothetical protein 4866395 3990691 UTI89_C4959 Escherichia coli UTI89 hypothetical protein YP_543893.1 4865994 R 364106 CDS YP_543894.1 91213908 3990692 complement(4866428..4867093) 1 NC_007946.1 hypothetical protein 4867093 3990692 UTI89_C4960 Escherichia coli UTI89 hypothetical protein YP_543894.1 4866428 R 364106 CDS YP_543895.1 91213909 3990693 complement(4867105..4867725) 1 NC_007946.1 hypothetical protein 4867725 3990693 UTI89_C4961 Escherichia coli UTI89 hypothetical protein YP_543895.1 4867105 R 364106 CDS YP_543896.1 91213910 3990694 complement(4867722..4868186) 1 NC_007946.1 hypothetical protein 4868186 3990694 UTI89_C4962 Escherichia coli UTI89 hypothetical protein YP_543896.1 4867722 R 364106 CDS YP_543897.1 91213911 3990695 complement(4868198..4869145) 1 NC_007946.1 hypothetical protein 4869145 3990695 UTI89_C4963 Escherichia coli UTI89 hypothetical protein YP_543897.1 4868198 R 364106 CDS YP_543898.1 91213912 3990696 complement(4869197..4872619) 1 NC_007946.1 hypothetical protein 4872619 3990696 UTI89_C4964 Escherichia coli UTI89 hypothetical protein YP_543898.1 4869197 R 364106 CDS YP_543899.1 91213913 3990697 complement(4872610..4873764) 1 NC_007946.1 hypothetical protein 4873764 3990697 UTI89_C4965 Escherichia coli UTI89 hypothetical protein YP_543899.1 4872610 R 364106 CDS YP_543900.1 91213914 3990698 complement(4873780..4874037) 1 NC_007946.1 hypothetical protein 4874037 3990698 UTI89_C4966 Escherichia coli UTI89 hypothetical protein YP_543900.1 4873780 R 364106 CDS YP_543901.1 91213915 3990699 complement(4874064..4875650) 1 NC_007946.1 hypothetical protein 4875650 3990699 UTI89_C4967 Escherichia coli UTI89 hypothetical protein YP_543901.1 4874064 R 364106 CDS YP_543902.1 91213916 3990700 complement(4875704..4875982) 1 NC_007946.1 hypothetical protein 4875982 3990700 UTI89_C4968 Escherichia coli UTI89 hypothetical protein YP_543902.1 4875704 R 364106 CDS YP_543903.1 91213917 3990701 complement(4875997..4876281) 1 NC_007946.1 hypothetical protein 4876281 3990701 UTI89_C4969 Escherichia coli UTI89 hypothetical protein YP_543903.1 4875997 R 364106 CDS YP_543904.1 91213918 3990702 complement(4876299..4876577) 1 NC_007946.1 hypothetical protein 4876577 3990702 UTI89_C4970 Escherichia coli UTI89 hypothetical protein YP_543904.1 4876299 R 364106 CDS YP_543905.1 91213919 3990703 4876758..4877018 1 NC_007946.1 hypothetical protein 4877018 3990703 UTI89_C4971 Escherichia coli UTI89 hypothetical protein YP_543905.1 4876758 D 364106 CDS YP_543906.1 91213920 3990704 complement(4877097..4877615) 1 NC_007946.1 hypothetical protein 4877615 3990704 UTI89_C4972 Escherichia coli UTI89 hypothetical protein YP_543906.1 4877097 R 364106 CDS YP_543907.1 91213921 3990705 complement(4877615..4878433) 1 NC_007946.1 hypothetical protein 4878433 3990705 UTI89_C4973 Escherichia coli UTI89 hypothetical protein YP_543907.1 4877615 R 364106 CDS YP_543908.1 91213922 3990706 complement(4878456..4879034) 1 NC_007946.1 hypothetical protein 4879034 3990706 UTI89_C4974 Escherichia coli UTI89 hypothetical protein YP_543908.1 4878456 R 364106 CDS YP_543909.1 91213923 3990707 complement(4879325..4880215) 1 NC_007946.1 hypothetical protein 4880215 3990707 UTI89_C4975 Escherichia coli UTI89 hypothetical protein YP_543909.1 4879325 R 364106 CDS YP_543910.1 91213924 3990708 complement(4880212..4880538) 1 NC_007946.1 hypothetical protein 4880538 3990708 UTI89_C4976 Escherichia coli UTI89 hypothetical protein YP_543910.1 4880212 R 364106 CDS YP_543911.1 91213925 3990709 4881012..4882190 1 NC_007946.1 hypothetical protein 4882190 3990709 UTI89_C4977 Escherichia coli UTI89 hypothetical protein YP_543911.1 4881012 D 364106 CDS YP_543912.1 91213926 3994329 4882183..4883634 1 NC_007946.1 Na+/H+ antiporter 4883634 3994329 UTI89_C4978 Escherichia coli UTI89 Na+/H+ antiporter YP_543912.1 4882183 D 364106 CDS YP_543913.1 91213927 3994330 4884434..4884913 1 NC_007946.1 hypothetical protein 4884913 3994330 UTI89_C4979 Escherichia coli UTI89 hypothetical protein YP_543913.1 4884434 D 364106 CDS YP_543914.1 91213928 3994331 complement(4884948..4885826) 1 NC_007946.1 hypothetical protein 4885826 3994331 UTI89_C4980 Escherichia coli UTI89 hypothetical protein YP_543914.1 4884948 R 364106 CDS YP_543915.1 91213929 3994332 complement(4886154..4886885) 1 NC_007946.1 hypothetical protein 4886885 3994332 UTI89_C4981 Escherichia coli UTI89 hypothetical protein YP_543915.1 4886154 R 364106 CDS YP_543916.1 91213930 3994333 4886296..4886442 1 NC_007946.1 hypothetical protein 4886442 3994333 UTI89_C4982 Escherichia coli UTI89 hypothetical protein YP_543916.1 4886296 D 364106 CDS YP_543917.1 91213931 3994334 complement(4888368..4889591) 1 NC_007946.1 hypothetical protein 4889591 3994334 UTI89_C4983 Escherichia coli UTI89 hypothetical protein YP_543917.1 4888368 R 364106 CDS YP_543918.1 91213932 3994335 4889692..4890576 1 NC_007946.1 hypothetical protein 4890576 3994335 UTI89_C4984 Escherichia coli UTI89 hypothetical protein YP_543918.1 4889692 D 364106 CDS YP_543919.1 91213933 3994336 4890595..4890750 1 NC_007946.1 hypothetical protein 4890750 3994336 UTI89_C4985 Escherichia coli UTI89 hypothetical protein YP_543919.1 4890595 D 364106 CDS YP_543920.1 91213934 3994337 4890779..4891459 1 NC_007946.1 hypothetical protein 4891459 3994337 UTI89_C4986 Escherichia coli UTI89 hypothetical protein YP_543920.1 4890779 D 364106 CDS YP_543921.1 91213935 3994338 complement(4891343..4891474) 1 NC_007946.1 hypothetical protein 4891474 3994338 UTI89_C4987 Escherichia coli UTI89 hypothetical protein YP_543921.1 4891343 R 364106 CDS YP_543922.1 91213936 3994339 4891502..4892284 1 NC_007946.1 hypothetical protein 4892284 3994339 UTI89_C4988 Escherichia coli UTI89 hypothetical protein YP_543922.1 4891502 D 364106 CDS YP_543923.1 91213937 3994340 4892290..4892523 1 NC_007946.1 hypothetical protein 4892523 ykfF 3994340 ykfF Escherichia coli UTI89 hypothetical protein YP_543923.1 4892290 D 364106 CDS YP_543924.1 91213938 3994341 4892613..4893431 1 NC_007946.1 hypothetical protein 4893431 3994341 UTI89_C4990 Escherichia coli UTI89 hypothetical protein YP_543924.1 4892613 D 364106 CDS YP_543925.1 91213939 3994342 4893522..4894007 1 NC_007946.1 hypothetical protein 4894007 3994342 UTI89_C4991 Escherichia coli UTI89 hypothetical protein YP_543925.1 4893522 D 364106 CDS YP_543926.1 91213940 3994343 complement(4893576..4893971) 1 NC_007946.1 hypothetical protein 4893971 3994343 UTI89_C4992 Escherichia coli UTI89 hypothetical protein YP_543926.1 4893576 R 364106 CDS YP_543927.1 91213941 3994344 complement(4893956..4894444) 1 NC_007946.1 hypothetical protein 4894444 3994344 UTI89_C4993 Escherichia coli UTI89 hypothetical protein YP_543927.1 4893956 R 364106 CDS YP_543928.1 91213942 3994345 4894022..4894498 1 NC_007946.1 hypothetical protein 4894498 yeeS2 3994345 yeeS2 Escherichia coli UTI89 hypothetical protein YP_543928.1 4894022 D 364106 CDS YP_543929.1 91213943 3994346 4894585..4894806 1 NC_007946.1 hypothetical protein 4894806 yeeT2 3994346 yeeT2 Escherichia coli UTI89 hypothetical protein YP_543929.1 4894585 D 364106 CDS YP_543930.1 91213944 3994347 4894886..4895254 1 NC_007946.1 hypothetical protein 4895254 yeeU2 3994347 yeeU2 Escherichia coli UTI89 hypothetical protein YP_543930.1 4894886 D 364106 CDS YP_543931.1 91213945 3992254 4895344..4895721 1 NC_007946.1 hypothetical protein 4895721 yeeV2 3992254 yeeV2 Escherichia coli UTI89 hypothetical protein YP_543931.1 4895344 D 364106 CDS YP_543932.1 91213946 3992255 4895718..4896206 1 NC_007946.1 hypothetical protein 4896206 3992255 UTI89_C4998 Escherichia coli UTI89 hypothetical protein YP_543932.1 4895718 D 364106 CDS YP_543933.1 91213947 3992256 4896218..4896415 1 NC_007946.1 hypothetical protein 4896415 3992256 UTI89_C4999 Escherichia coli UTI89 hypothetical protein YP_543933.1 4896218 D 364106 CDS YP_543934.1 91213948 3992257 4896500..4896652 1 NC_007946.1 hypothetical protein 4896652 3992257 UTI89_C5000 Escherichia coli UTI89 hypothetical protein YP_543934.1 4896500 D 364106 CDS YP_543935.1 91213949 3992258 4896671..4897135 1 NC_007946.1 hypothetical protein 4897135 3992258 UTI89_C5001 Escherichia coli UTI89 hypothetical protein YP_543935.1 4896671 D 364106 CDS YP_543936.1 91213950 3992259 4897664..4899640 1 NC_007946.1 hypothetical protein 4899640 3992259 UTI89_C5002 Escherichia coli UTI89 hypothetical protein YP_543936.1 4897664 D 364106 CDS YP_543937.1 91213951 3992260 complement(4900039..4900218) 1 NC_007946.1 hypothetical protein 4900218 3992260 UTI89_C5003 Escherichia coli UTI89 hypothetical protein YP_543937.1 4900039 R 364106 CDS YP_543938.1 91213952 3992261 complement(4900263..4901168) 1 NC_007946.1 hypothetical protein 4901168 3992261 UTI89_C5004 Escherichia coli UTI89 hypothetical protein YP_543938.1 4900263 R 364106 CDS YP_543939.1 91213953 3992262 complement(4901347..4902327) 1 NC_007946.1 hypothetical protein 4902327 yjhS 3992262 yjhS Escherichia coli UTI89 hypothetical protein YP_543939.1 4901347 R 364106 CDS YP_543940.1 91213954 3992263 complement(4902392..4903606) 1 NC_007946.1 N-acetylneuraminic acid mutarotase 4903606 3992263 UTI89_C5006 Escherichia coli UTI89 N-acetylneuraminic acid mutarotase YP_543940.1 4902392 R 364106 CDS YP_543941.1 91213955 3992264 complement(4903518..4904243) 1 NC_007946.1 hypothetical protein 4904243 yjhA 3992264 yjhA Escherichia coli UTI89 hypothetical protein YP_543941.1 4903518 R 364106 CDS YP_543942.1 91213956 3992265 complement(4905033..4905440) 1 NC_007946.1 hypothetical protein 4905440 3992265 UTI89_C5008 Escherichia coli UTI89 hypothetical protein YP_543942.1 4905033 R 364106 CDS YP_543943.1 91213957 3992266 4905700..4906302 1 NC_007946.1 inversion of on/off regulator of fimA; tyrosine recombinase 4906302 fimB 3992266 fimB Escherichia coli UTI89 tyrosine recombinase YP_543943.1 4905700 D 364106 CDS YP_543944.1 91213958 3992267 4906780..4907376 1 NC_007946.1 inversion of on/off regulator of fimA; tyrosine recombinase 4907376 fimE 3992267 fimE Escherichia coli UTI89 tyrosine recombinase YP_543944.1 4906780 D 364106 CDS YP_543945.1 91213959 3992268 4907857..4908411 1 NC_007946.1 type 1 fimbriae major subunit FimA 4908411 fimA 3992268 fimA Escherichia coli UTI89 type 1 fimbriae major subunit FimA YP_543945.1 4907857 D 364106 CDS YP_543946.1 91213960 3992269 4908368..4909015 1 NC_007946.1 FimI fimbrial protein 4909015 fimI 3992269 fimI Escherichia coli UTI89 FimI fimbrial protein YP_543946.1 4908368 D 364106 CDS YP_543947.1 91213961 3992270 4909052..4909777 1 NC_007946.1 periplasmic chaperone protein FimC 4909777 fimC 3992270 fimC Escherichia coli UTI89 periplasmic chaperone protein FimC YP_543947.1 4909052 D 364106 CDS YP_543948.1 91213962 3992271 4909843..4912479 1 NC_007946.1 outer membrane usher protein FimD 4912479 fimD 3992271 fimD Escherichia coli UTI89 outer membrane usher protein FimD YP_543948.1 4909843 D 364106 CDS YP_543949.1 91213963 3992272 4912489..4913019 1 NC_007946.1 type 1 fimbriae minor subunit FimF 4913019 fimF 3992272 fimF Escherichia coli UTI89 type 1 fimbriae minor subunit FimF YP_543949.1 4912489 D 364106 CDS YP_543950.1 91213964 3992273 4913032..4913535 1 NC_007946.1 type 1 fimbriae minor subunit FimG 4913535 fimG 3992273 fimG Escherichia coli UTI89 type 1 fimbriae minor subunit FimG YP_543950.1 4913032 D 364106 CDS YP_543951.1 91213965 3992235 4913555..4914457 1 NC_007946.1 type 1 fimbiral adhesin FimH 4914457 fimH 3992235 fimH Escherichia coli UTI89 type 1 fimbiral adhesin FimH YP_543951.1 4913555 D 364106 CDS YP_543952.1 91213966 3992236 4915186..4916370 1 NC_007946.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4916370 uxuA 3992236 uxuA Escherichia coli UTI89 mannonate dehydratase YP_543952.1 4915186 D 364106 CDS YP_543953.1 91213967 3992237 4916451..4917911 1 NC_007946.1 D-mannonate oxidoreductase 4917911 uxuB 3992237 uxuB Escherichia coli UTI89 D-mannonate oxidoreductase YP_543953.1 4916451 D 364106 CDS YP_543954.1 91213968 3992238 4918126..4918899 1 NC_007946.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4918899 uxuR 3992238 uxuR Escherichia coli UTI89 DNA-binding transcriptional repressor UxuR YP_543954.1 4918126 D 364106 CDS YP_543955.1 91213969 3992239 4919313..4919696 1 NC_007946.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4919696 iraD 3992239 iraD Escherichia coli UTI89 DNA replication/recombination/repair protein YP_543955.1 4919313 D 364106 CDS YP_543956.1 91213970 3992240 complement(4919744..4922125) 1 NC_007946.1 phosphoenolpyruvate-protein phosphoryltransferase PptE 4922125 pptE 3992240 pptE Escherichia coli UTI89 phosphoenolpyruvate-protein phosphoryltransferase PptE YP_543956.1 4919744 R 364106 CDS YP_543957.1 91213971 3992241 complement(4922129..4922761) 1 NC_007946.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 4922761 pgdK 3992241 pgdK Escherichia coli UTI89 dihydroxyacetone kinase subunit DhaL YP_543957.1 4922129 R 364106 CDS YP_543958.1 91213972 3992242 complement(4922774..4923844) 1 NC_007946.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 4923844 3992242 UTI89_C5024 Escherichia coli UTI89 dihydroxyacetone kinase subunit DhaK YP_543958.1 4922774 R 364106 CDS YP_543959.1 91213973 3992243 4924163..4925245 1 NC_007946.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4925245 gldA 3992243 gldA Escherichia coli UTI89 glycerol dehydrogenase YP_543959.1 4924163 D 364106 CDS YP_543960.1 91213974 3992244 4925312..4926580 1 NC_007946.1 transporter CgxT 4926580 cgxT 3992244 cgxT Escherichia coli UTI89 transporter CgxT YP_543960.1 4925312 D 364106 CDS YP_543961.1 91213975 3992245 4926598..4927962 1 NC_007946.1 dihydrolipoamide dehydrogenase CdlD 4927962 cdlD 3992245 cdlD Escherichia coli UTI89 dihydrolipoamide dehydrogenase CdlD YP_543961.1 4926598 D 364106 CDS YP_543962.1 91213976 3992246 4928263..4929804 1 NC_007946.1 carnitine transporter CniT 4929804 cniT 3992246 cniT Escherichia coli UTI89 carnitine transporter CniT YP_543962.1 4928263 D 364106 CDS YP_543963.1 91213977 3992247 complement(4929860..4931002) 1 NC_007946.1 glycerate kinase GclK 4931002 gclK 3992247 gclK Escherichia coli UTI89 glycerate kinase GclK YP_543963.1 4929860 R 364106 CDS YP_543964.1 91213978 3992248 complement(4931077..4931964) 1 NC_007946.1 3-hydroxyisobutyrate dehydrogenase 4931964 ghbD 3992248 ghbD Escherichia coli UTI89 3-hydroxyisobutyrate dehydrogenase YP_543964.1 4931077 R 364106 CDS YP_543965.1 91213979 3992249 complement(4931982..4932764) 1 NC_007946.1 regulatory protein GclR 4932764 gclR 3992249 gclR Escherichia coli UTI89 regulatory protein GclR YP_543965.1 4931982 R 364106 CDS YP_543966.1 91213980 3992250 complement(4932777..4934516) 1 NC_007946.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 4934516 gclA 3992250 gclA Escherichia coli UTI89 glyoxylate carboligase YP_543966.1 4932777 R 364106 CDS YP_543967.1 91213981 3992251 4934895..4936844 1 NC_007946.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 4936844 ibgR 3992251 ibgR Escherichia coli UTI89 DNA-binding transcriptional regulator DhaR YP_543967.1 4934895 D 364106 CDS YP_543968.1 91213982 3992252 complement(4936851..4937108) 1 NC_007946.1 hypothetical protein 4937108 3992252 UTI89_C5034 Escherichia coli UTI89 hypothetical protein YP_543968.1 4936851 R 364106 CDS YP_543969.1 91213983 3992253 4937131..4938501 1 NC_007946.1 invasion protein IbeA 4938501 ibeA 3992253 ibeA Escherichia coli UTI89 invasion protein IbeA YP_543969.1 4937131 D 364106 CDS YP_543970.1 91213984 3991738 4938516..4939919 1 NC_007946.1 transporter IbgT 4939919 ibgT 3991738 ibgT Escherichia coli UTI89 transporter IbgT YP_543970.1 4938516 D 364106 CDS YP_543971.1 91213985 3991739 complement(4940006..4940734) 1 NC_007946.1 DNA-binding transcriptional regulator 4940734 yjiE 3991739 yjiE Escherichia coli UTI89 DNA-binding transcriptional regulator YP_543971.1 4940006 R 364106 CDS YP_543972.1 91213986 3991740 complement(4940982..4942154) 1 NC_007946.1 isoaspartyl dipeptidase 4942154 iadA 3991740 iadA Escherichia coli UTI89 isoaspartyl dipeptidase YP_543972.1 4940982 R 364106 CDS YP_543973.1 91213987 3991741 complement(4942167..4942628) 1 NC_007946.1 hypothetical protein 4942628 yjiG 3991741 yjiG Escherichia coli UTI89 hypothetical protein YP_543973.1 4942167 R 364106 CDS YP_543974.1 91213988 3991742 complement(4942625..4943320) 1 NC_007946.1 hypothetical protein 4943320 yjiH 3991742 yjiH Escherichia coli UTI89 hypothetical protein YP_543974.1 4942625 R 364106 CDS YP_543975.1 91213989 3991743 complement(4944124..4945302) 1 NC_007946.1 hypothetical protein 4945302 yjiJ 3991743 yjiJ Escherichia coli UTI89 hypothetical protein YP_543975.1 4944124 R 364106 CDS YP_543976.1 91213990 3991744 complement(4945370..4946341) 1 NC_007946.1 hypothetical protein 4946341 yjiK 3991744 yjiK Escherichia coli UTI89 hypothetical protein YP_543976.1 4945370 R 364106 CDS YP_543977.1 91213991 3991745 complement(4946295..4946552) 1 NC_007946.1 hypothetical protein 4946552 3991745 UTI89_C5043 Escherichia coli UTI89 hypothetical protein YP_543977.1 4946295 R 364106 CDS YP_543978.1 91213992 3991746 complement(4946549..4947322) 1 NC_007946.1 hypothetical protein 4947322 yjiL 3991746 yjiL Escherichia coli UTI89 hypothetical protein YP_543978.1 4946549 R 364106 CDS YP_543979.1 91213993 3991747 complement(4947326..4948498) 1 NC_007946.1 hypothetical protein 4948498 yjiM 3991747 yjiM Escherichia coli UTI89 hypothetical protein YP_543979.1 4947326 R 364106 CDS YP_543980.1 91213994 3991748 complement(4948593..4949909) 1 NC_007946.1 hypothetical protein 4949909 yjiN 3991748 yjiN Escherichia coli UTI89 hypothetical protein YP_543980.1 4948593 R 364106 CDS YP_543981.1 91213995 3991749 4950058..4950978 1 NC_007946.1 hypothetical protein 4950978 3991749 UTI89_C5047 Escherichia coli UTI89 hypothetical protein YP_543981.1 4950058 D 364106 CDS YP_543982.1 91213996 3991750 4951258..4953477 1 NC_007946.1 hypothetical protein 4953477 3991750 UTI89_C5048 Escherichia coli UTI89 hypothetical protein YP_543982.1 4951258 D 364106 CDS YP_543983.1 91213997 3991751 complement(4953524..4953865) 1 NC_007946.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 4953865 yjiW 3991751 yjiW Escherichia coli UTI89 endoribonuclease SymE YP_543983.1 4953524 R 364106 CDS YP_543984.1 91213998 3991752 complement(4954094..4955461) 1 NC_007946.1 specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS 4955461 hsdS 3991752 hsdS Escherichia coli UTI89 EcoKI restriction-modification system protein HsdS YP_543984.1 4954094 R 364106 CDS YP_543985.1 91213999 3991753 complement(4955458..4957047) 1 NC_007946.1 DNA methylase M 4957047 hsdM 3991753 hsdM Escherichia coli UTI89 DNA methylase M YP_543985.1 4955458 R 364106 CDS YP_543986.1 91214000 3991754 complement(4957133..4957243) 1 NC_007946.1 hypothetical protein 4957243 3991754 UTI89_C5052 Escherichia coli UTI89 hypothetical protein YP_543986.1 4957133 R 364106 CDS YP_543987.1 91214001 3991755 complement(4957249..4960758) 1 NC_007946.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R 4960758 hsdR 3991755 hsdR Escherichia coli UTI89 type I restriction enzyme EcoKI subunit R YP_543987.1 4957249 R 364106 CDS YP_543988.1 91214002 3991756 4960949..4961863 1 NC_007946.1 Mrr protein 4961863 mrr 3991756 mrr Escherichia coli UTI89 Mrr protein YP_543988.1 4960949 D 364106 CDS YP_543989.1 91214003 3991757 complement(4961909..4962904) 1 NC_007946.1 GTP-binding protein YjiA 4962904 yjiA 3991757 yjiA Escherichia coli UTI89 GTP-binding protein YjiA YP_543989.1 4961909 R 364106 CDS YP_543990.1 91214004 3994519 complement(4962876..4963079) 1 NC_007946.1 hypothetical protein 4963079 3994519 UTI89_C5056 Escherichia coli UTI89 hypothetical protein YP_543990.1 4962876 R 364106 CDS YP_543991.1 91214005 3994520 complement(4963197..4965362) 1 NC_007946.1 hypothetical protein 4965362 yjiY 3994520 yjiY Escherichia coli UTI89 hypothetical protein YP_543991.1 4963197 R 364106 CDS YP_543992.1 91214006 3994521 4965724..4967379 1 NC_007946.1 tsr subunit of methyl-accepting chemotaxis protein I 4967379 tsr 3994521 tsr Escherichia coli UTI89 tsr subunit of methyl-accepting chemotaxis protein I YP_543992.1 4965724 D 364106 CDS YP_543993.1 91214007 3994522 complement(4967422..4968693) 1 NC_007946.1 hypothetical protein 4968693 3994522 UTI89_C5059 Escherichia coli UTI89 hypothetical protein YP_543993.1 4967422 R 364106 CDS YP_543994.1 91214008 3994523 complement(4968690..4969163) 1 NC_007946.1 hypothetical protein 4969163 3994523 UTI89_C5060 Escherichia coli UTI89 hypothetical protein YP_543994.1 4968690 R 364106 CDS YP_543995.1 91214009 3994524 complement(4969227..4970198) 1 NC_007946.1 C4-dicarboxylate-binding periplasmic protein 4970198 3994524 UTI89_C5061 Escherichia coli UTI89 C4-dicarboxylate-binding periplasmic protein YP_543995.1 4969227 R 364106 CDS YP_543996.1 91214010 3994525 4970868..4972541 1 NC_007946.1 Na(+)/H(+) exchanger YjcE 4972541 3994525 UTI89_C5062 Escherichia coli UTI89 Na(+)/H(+) exchanger YjcE YP_543996.1 4970868 D 364106 CDS YP_543997.1 91214011 3994526 complement(4972712..4973617) 1 NC_007946.1 hypothetical protein 4973617 yjjM 3994526 yjjM Escherichia coli UTI89 hypothetical protein YP_543997.1 4972712 R 364106 CDS YP_543998.1 91214012 3994527 4973756..4974778 1 NC_007946.1 zinc-type alcohol dehydrogenase-like protein YjjN 4974778 3994527 UTI89_C5064 Escherichia coli UTI89 zinc-type alcohol dehydrogenase-like protein YjjN YP_543998.1 4973756 D 364106 CDS YP_543999.1 91214013 3994528 complement(4974918..4977209) 1 NC_007946.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4977209 mdoB 3994528 mdoB Escherichia coli UTI89 phosphoglycerol transferase I YP_543999.1 4974918 R 364106 CDS YP_544000.1 91214014 3994529 complement(4977463..4977960) 1 NC_007946.1 hypothetical protein 4977960 yjjA 3994529 yjjA Escherichia coli UTI89 hypothetical protein YP_544000.1 4977463 R 364106 CDS YP_544001.1 91214015 3994530 complement(4978006..4978743) 1 NC_007946.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4978743 dnaC 3994530 dnaC Escherichia coli UTI89 DNA replication protein DnaC YP_544001.1 4978006 R 364106 CDS YP_544002.1 91214016 3994531 complement(4978746..4979285) 1 NC_007946.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4979285 dnaT 3994531 dnaT Escherichia coli UTI89 primosomal protein DnaI YP_544002.1 4978746 R 364106 CDS YP_544003.1 91214017 3994532 complement(4979393..4979881) 1 NC_007946.1 hypothetical protein 4979881 yjjB 3994532 yjjB Escherichia coli UTI89 hypothetical protein YP_544003.1 4979393 R 364106 CDS YP_544004.1 91214018 3994533 complement(4979857..4980690) 1 NC_007946.1 hypothetical protein 4980690 yjjP 3994533 yjjP Escherichia coli UTI89 hypothetical protein YP_544004.1 4979857 R 364106 CDS YP_544005.1 91214019 3994534 4981247..4981972 1 NC_007946.1 hypothetical protein 4981972 yjjQ 3994534 yjjQ Escherichia coli UTI89 hypothetical protein YP_544005.1 4981247 D 364106 CDS YP_544006.2 162138299 3994535 4981984..4982607 1 NC_007946.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4982607 bglJ 3994535 bglJ Escherichia coli UTI89 DNA-binding transcriptional activator BglJ YP_544006.2 4981984 D 364106 CDS YP_544007.1 91214021 3994536 complement(4982645..4983433) 1 NC_007946.1 ferric iron reductase involved in ferric hydroximate transport 4983433 fhuF 3994536 fhuF Escherichia coli UTI89 ferric iron reductase involved in ferric hydroximate transport YP_544007.1 4982645 R 364106 CDS YP_544008.1 91214022 3994537 4983463..4983810 1 NC_007946.1 hypothetical protein 4983810 3994537 UTI89_C5074 Escherichia coli UTI89 hypothetical protein YP_544008.1 4983463 D 364106 CDS YP_544009.1 91214023 3992072 complement(4984237..4984359) 1 NC_007946.1 hypothetical protein 4984359 3992072 UTI89_C5078 Escherichia coli UTI89 hypothetical protein YP_544009.1 4984237 R 364106 CDS YP_544010.1 91214024 3992073 complement(4984371..4985402) 1 NC_007946.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4985402 rsmC 3992073 rsmC Escherichia coli UTI89 16S ribosomal RNA m2G1207 methyltransferase YP_544010.1 4984371 R 364106 CDS YP_544012.1 91214026 3992075 4985505..4985918 1 NC_007946.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4985918 holD 3992075 holD Escherichia coli UTI89 DNA polymerase III subunit psi YP_544012.1 4985505 D 364106 CDS YP_544013.1 91214027 3992076 4985887..4986333 1 NC_007946.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4986333 rimI 3992076 rimI Escherichia coli UTI89 ribosomal-protein-alanine N-acetyltransferase YP_544013.1 4985887 D 364106 CDS YP_544014.1 91214028 3992077 4986348..4987025 1 NC_007946.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4987025 yjjG 3992077 yjjG Escherichia coli UTI89 nucleotidase YP_544014.1 4986348 D 364106 CDS YP_544015.1 91214029 3992078 4987089..4987190 1 NC_007946.1 peptide chain release factor 3 4987190 3992078 UTI89_C5084 Escherichia coli UTI89 peptide chain release factor 3 YP_544015.1 4987089 D 364106 CDS YP_544016.1 91214030 3992079 4987411..4988625 1 NC_007946.1 integrase-like protein 4988625 3992079 UTI89_C5085 Escherichia coli UTI89 integrase-like protein YP_544016.1 4987411 D 364106 CDS YP_544017.1 91214031 3992080 complement(4989001..4989996) 1 NC_007946.1 hypothetical protein 4989996 3992080 UTI89_C5086 Escherichia coli UTI89 hypothetical protein YP_544017.1 4989001 R 364106 CDS YP_544018.1 91214032 3992081 complement(4990564..4991358) 1 NC_007946.1 hypothetical protein 4991358 3992081 UTI89_C5087 Escherichia coli UTI89 hypothetical protein YP_544018.1 4990564 R 364106 CDS YP_544019.1 91214033 3992082 complement(4991355..4991720) 1 NC_007946.1 hypothetical protein 4991720 3992082 UTI89_C5088 Escherichia coli UTI89 hypothetical protein YP_544019.1 4991355 R 364106 CDS YP_544020.1 91214034 3992083 complement(4991722..4992078) 1 NC_007946.1 hypothetical protein 4992078 3992083 UTI89_C5089 Escherichia coli UTI89 hypothetical protein YP_544020.1 4991722 R 364106 CDS YP_544021.1 91214035 3992084 complement(4992078..4992440) 1 NC_007946.1 hypothetical protein 4992440 3992084 UTI89_C5090 Escherichia coli UTI89 hypothetical protein YP_544021.1 4992078 R 364106 CDS YP_544022.1 91214036 3994363 complement(4992431..4992967) 1 NC_007946.1 hypothetical protein 4992967 yfdR2 3994363 yfdR2 Escherichia coli UTI89 hypothetical protein YP_544022.1 4992431 R 364106 CDS YP_544023.1 91214037 3994364 complement(4993095..4993919) 1 NC_007946.1 hypothetical protein 4993919 yfdQ2 3994364 yfdQ2 Escherichia coli UTI89 hypothetical protein YP_544023.1 4993095 R 364106 CDS YP_544024.1 91214038 3994365 complement(4993985..4994533) 1 NC_007946.1 hypothetical protein 4994533 3994365 UTI89_C5093 Escherichia coli UTI89 hypothetical protein YP_544024.1 4993985 R 364106 CDS YP_544025.1 91214039 3994366 4994605..4994973 1 NC_007946.1 hypothetical protein 4994973 3994366 UTI89_C5094 Escherichia coli UTI89 hypothetical protein YP_544025.1 4994605 D 364106 CDS YP_544026.1 91214040 3994367 complement(4995070..4995762) 1 NC_007946.1 regulatory protein 4995762 3994367 UTI89_C5095 Escherichia coli UTI89 regulatory protein YP_544026.1 4995070 R 364106 CDS YP_544027.1 91214041 3994368 4995860..4996120 1 NC_007946.1 hypothetical protein 4996120 3994368 UTI89_C5096 Escherichia coli UTI89 hypothetical protein YP_544027.1 4995860 D 364106 CDS YP_544028.1 91214042 3994369 4996113..4996664 1 NC_007946.1 hypothetical protein 4996664 3994369 UTI89_C5097 Escherichia coli UTI89 hypothetical protein YP_544028.1 4996113 D 364106 CDS YP_544029.1 91214043 3994370 4996661..4997812 1 NC_007946.1 antirepressor 4997812 3994370 UTI89_C5098 Escherichia coli UTI89 antirepressor YP_544029.1 4996661 D 364106 CDS YP_544030.1 91214044 3994371 4997809..4998033 1 NC_007946.1 hypothetical protein 4998033 3994371 UTI89_C5099 Escherichia coli UTI89 hypothetical protein YP_544030.1 4997809 D 364106 CDS YP_544031.1 91214045 3994372 4998030..4998848 1 NC_007946.1 replication protein 4998848 3994372 UTI89_C5100 Escherichia coli UTI89 replication protein YP_544031.1 4998030 D 364106 CDS YP_544032.1 91214046 3994373 4998845..4999339 1 NC_007946.1 hypothetical protein 4999339 yfdN2 3994373 yfdN2 Escherichia coli UTI89 hypothetical protein YP_544032.1 4998845 D 364106 CDS YP_544033.1 91214047 3994374 4999339..4999992 1 NC_007946.1 DNA adenine methylase 4999992 3994374 UTI89_C5102 Escherichia coli UTI89 DNA adenine methylase YP_544033.1 4999339 D 364106 CDS YP_544034.1 91214048 3994375 4999989..5000315 1 NC_007946.1 hypothetical protein 5000315 3994375 UTI89_C5103 Escherichia coli UTI89 hypothetical protein YP_544034.1 4999989 D 364106 CDS YP_544035.1 91214049 3994376 5000312..5000701 1 NC_007946.1 hypothetical protein 5000701 3994376 UTI89_C5104 Escherichia coli UTI89 hypothetical protein YP_544035.1 5000312 D 364106 CDS YP_544036.1 91214050 3994377 5000721..5001518 1 NC_007946.1 hypothetical protein 5001518 3994377 UTI89_C5105 Escherichia coli UTI89 hypothetical protein YP_544036.1 5000721 D 364106 CDS YP_544037.1 91214051 3994378 5001520..5002515 1 NC_007946.1 hypothetical protein 5002515 ydfU2 3994378 ydfU2 Escherichia coli UTI89 hypothetical protein YP_544037.1 5001520 D 364106 CDS YP_544038.1 91214052 3994379 5002533..5002898 1 NC_007946.1 Q protein 5002898 ybcQ2 3994379 ybcQ2 Escherichia coli UTI89 Q protein YP_544038.1 5002533 D 364106 CDS YP_544039.1 91214053 3994380 complement(5002983..5003429) 1 NC_007946.1 hypothetical protein 5003429 3994380 UTI89_C5108 Escherichia coli UTI89 hypothetical protein YP_544039.1 5002983 R 364106 CDS YP_544040.1 91214054 3994381 5003676..5003903 1 NC_007946.1 prophage CP-933O hypothetical protein 5003903 3994381 UTI89_C5109 Escherichia coli UTI89 prophage CP-933O hypothetical protein YP_544040.1 5003676 D 364106 CDS YP_544041.1 91214055 3994382 5004054..5005106 1 NC_007946.1 hypothetical protein 5005106 3994382 UTI89_C5110 Escherichia coli UTI89 hypothetical protein YP_544041.1 5004054 D 364106 CDS YP_544042.1 91214056 3993737 5005174..5005389 1 NC_007946.1 lambdoid prophage DLP12 lysis protein S-like protein 5005389 ybcR2 3993737 ybcR2 Escherichia coli UTI89 lambdoid prophage DLP12 lysis protein S-like protein YP_544042.1 5005174 D 364106 CDS YP_544043.1 91214057 3993738 5005389..5005886 1 NC_007946.1 bacteriophage lambda lysozyme-like protein 5005886 ybcS2 3993738 ybcS2 Escherichia coli UTI89 bacteriophage lambda lysozyme-like protein YP_544043.1 5005389 D 364106 CDS YP_544044.1 91214058 3993739 5005883..5006350 1 NC_007946.1 endopeptidase Rz of prophage CP-933K 5006350 3993739 UTI89_C5113 Escherichia coli UTI89 endopeptidase Rz of prophage CP-933K YP_544044.1 5005883 D 364106 CDS YP_544045.1 91214059 3993740 5006338..5006490 1 NC_007946.1 hypothetical protein 5006490 3993740 UTI89_C5114 Escherichia coli UTI89 hypothetical protein YP_544045.1 5006338 D 364106 CDS YP_544046.1 91214060 3993741 5006736..5007176 1 NC_007946.1 hypothetical protein 5007176 3993741 UTI89_C5115 Escherichia coli UTI89 hypothetical protein YP_544046.1 5006736 D 364106 CDS YP_544047.1 91214061 3993742 5007166..5007657 1 NC_007946.1 hypothetical protein 5007657 3993742 UTI89_C5116 Escherichia coli UTI89 hypothetical protein YP_544047.1 5007166 D 364106 CDS YP_544048.1 91214062 3993743 5007657..5009759 1 NC_007946.1 prophage prophage DNA packaging protein 5009759 3993743 UTI89_C5117 Escherichia coli UTI89 prophage prophage DNA packaging protein YP_544048.1 5007657 D 364106 CDS YP_544049.1 91214063 3993744 5009750..5009968 1 NC_007946.1 hypothetical protein 5009968 3993744 UTI89_C5118 Escherichia coli UTI89 hypothetical protein YP_544049.1 5009750 D 364106 CDS YP_544050.1 91214064 3993745 5009896..5011476 1 NC_007946.1 portal protein 5011476 3993745 UTI89_C5119 Escherichia coli UTI89 portal protein YP_544050.1 5009896 D 364106 CDS YP_544051.1 91214065 3993746 5011325..5013448 1 NC_007946.1 protease/scaffold protein 5013448 3993746 UTI89_C5120 Escherichia coli UTI89 protease/scaffold protein YP_544051.1 5011325 D 364106 CDS YP_544052.1 91214066 3993747 5013490..5013858 1 NC_007946.1 hypothetical protein 5013858 3993747 UTI89_C5121 Escherichia coli UTI89 hypothetical protein YP_544052.1 5013490 D 364106 CDS YP_544053.1 91214067 3993748 5013851..5014126 1 NC_007946.1 prophage CP-933K hypothetical protein 5014126 3993748 UTI89_C5122 Escherichia coli UTI89 prophage CP-933K hypothetical protein YP_544053.1 5013851 D 364106 CDS YP_544054.1 91214068 3993749 5014138..5014728 1 NC_007946.1 tail component of prophage CP-933K 5014728 3993749 UTI89_C5123 Escherichia coli UTI89 tail component of prophage CP-933K YP_544054.1 5014138 D 364106 CDS YP_544055.1 91214069 3993750 5014725..5015126 1 NC_007946.1 tail component of prophage CP-933K 5015126 3993750 UTI89_C5124 Escherichia coli UTI89 tail component of prophage CP-933K YP_544055.1 5014725 D 364106 CDS YP_544056.1 91214070 3993751 5015131..5015880 1 NC_007946.1 tail component of prophage CP-933K 5015880 3993751 UTI89_C5125 Escherichia coli UTI89 tail component of prophage CP-933K YP_544056.1 5015131 D 364106 CDS YP_544057.1 91214071 3993752 5015938..5016327 1 NC_007946.1 tail component of prophage CP-933K 5016327 3993752 UTI89_C5126 Escherichia coli UTI89 tail component of prophage CP-933K YP_544057.1 5015938 D 364106 CDS YP_544058.1 91214072 3993753 5016336..5016665 1 NC_007946.1 minor tail protein 5016665 3993753 UTI89_C5127 Escherichia coli UTI89 minor tail protein YP_544058.1 5016336 D 364106 CDS YP_544059.1 91214073 3993754 5016637..5019693 1 NC_007946.1 tail length tape measure protein 5019693 3993754 UTI89_C5128 Escherichia coli UTI89 tail length tape measure protein YP_544059.1 5016637 D 364106 CDS YP_544060.1 91214074 3993755 5019693..5020022 1 NC_007946.1 minor tail protein 5020022 3993755 UTI89_C5129 Escherichia coli UTI89 minor tail protein YP_544060.1 5019693 D 364106 CDS YP_544061.1 91214075 3993560 5020032..5020730 1 NC_007946.1 minor tail protein 5020730 3993560 UTI89_C5130 Escherichia coli UTI89 minor tail protein YP_544061.1 5020032 D 364106 CDS YP_544062.1 91214076 3993561 5020693..5021478 1 NC_007946.1 prophage tail fiber component K 5021478 3993561 UTI89_C5131 Escherichia coli UTI89 prophage tail fiber component K YP_544062.1 5020693 D 364106 CDS YP_544063.1 91214077 3993562 5021376..5022023 1 NC_007946.1 tail component of prophage CP-933K 5022023 3993562 UTI89_C5132 Escherichia coli UTI89 tail component of prophage CP-933K YP_544063.1 5021376 D 364106 CDS YP_544064.1 91214078 3993563 5022084..5025479 1 NC_007946.1 prophage tail component 5025479 3993563 UTI89_C5133 Escherichia coli UTI89 prophage tail component YP_544064.1 5022084 D 364106 CDS YP_544065.1 91214079 3993564 5025547..5026146 1 NC_007946.1 prophage protein 5026146 3993564 UTI89_C5134 Escherichia coli UTI89 prophage protein YP_544065.1 5025547 D 364106 CDS YP_544066.1 91214080 3993565 5026211..5028586 1 NC_007946.1 hypothetical protein 5028586 3993565 UTI89_C5135 Escherichia coli UTI89 hypothetical protein YP_544066.1 5026211 D 364106 CDS YP_544067.1 91214081 3993566 complement(5026576..5027016) 1 NC_007946.1 hypothetical protein 5027016 3993566 UTI89_C5136 Escherichia coli UTI89 hypothetical protein YP_544067.1 5026576 R 364106 CDS YP_544068.1 91214082 3993567 5028586..5028867 1 NC_007946.1 hypothetical protein 5028867 3993567 UTI89_C5137 Escherichia coli UTI89 hypothetical protein YP_544068.1 5028586 D 364106 CDS YP_544069.1 91214083 3993568 5028877..5029917 1 NC_007946.1 hypothetical protein 5029917 3993568 UTI89_C5138 Escherichia coli UTI89 hypothetical protein YP_544069.1 5028877 D 364106 CDS YP_544070.1 91214084 3993569 complement(5030040..5030504) 1 NC_007946.1 hypothetical protein 5030504 3993569 UTI89_C5139 Escherichia coli UTI89 hypothetical protein YP_544070.1 5030040 R 364106 CDS YP_544071.1 91214085 3993570 complement(5030557..5031315) 1 NC_007946.1 hypothetical protein 5031315 3993570 UTI89_C5140 Escherichia coli UTI89 hypothetical protein YP_544071.1 5030557 R 364106 CDS YP_544072.1 91214086 3993571 complement(5031414..5032448) 1 NC_007946.1 hypothetical protein 5032448 3993571 UTI89_C5141 Escherichia coli UTI89 hypothetical protein YP_544072.1 5031414 R 364106 CDS YP_544073.1 91214087 3993572 5032591..5032848 1 NC_007946.1 hypothetical protein 5032848 3993572 UTI89_C5142 Escherichia coli UTI89 hypothetical protein YP_544073.1 5032591 D 364106 CDS YP_544074.1 91214088 3993573 complement(5032895..5033143) 1 NC_007946.1 DNA damage-inducible protein 5033143 3993573 UTI89_C5143 Escherichia coli UTI89 DNA damage-inducible protein YP_544074.1 5032895 R 364106 CDS YP_544075.1 91214089 3993574 5033363..5034949 1 NC_007946.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5034949 prfC 3993574 prfC Escherichia coli UTI89 peptide chain release factor 3 YP_544075.1 5033363 D 364106 CDS YP_544076.1 91214090 3993575 5035264..5035947 1 NC_007946.1 periplasmic protein 5035947 osmY 3993575 osmY Escherichia coli UTI89 periplasmic protein YP_544076.1 5035264 D 364106 CDS YP_544077.1 91214091 3993576 5036044..5036235 1 NC_007946.1 hypothetical protein 5036235 3993576 UTI89_C5146 Escherichia coli UTI89 hypothetical protein YP_544077.1 5036044 D 364106 CDS YP_544078.1 91214092 3993577 5036321..5037430 1 NC_007946.1 hypothetical protein 5037430 yjjU 3993577 yjjU Escherichia coli UTI89 hypothetical protein YP_544078.1 5036321 D 364106 CDS YP_544079.1 91214093 3993578 5037427..5038206 1 NC_007946.1 deoxyribonuclease YjjV 5038206 yjjV 3993578 yjjV Escherichia coli UTI89 deoxyribonuclease YjjV YP_544079.1 5037427 D 364106 CDS YP_544080.1 91214094 3993579 complement(5038423..5039286) 1 NC_007946.1 hypothetical protein 5039286 yjjW 3993579 yjjW Escherichia coli UTI89 hypothetical protein YP_544080.1 5038423 R 364106 CDS YP_544081.1 91214095 3993541 complement(5039258..5040808) 1 NC_007946.1 hypothetical protein 5040808 yjjI 3993541 yjjI Escherichia coli UTI89 hypothetical protein YP_544081.1 5039258 R 364106 CDS YP_544082.1 91214096 3993542 5040784..5040909 1 NC_007946.1 hypothetical protein 5040909 3993542 UTI89_C5151 Escherichia coli UTI89 hypothetical protein YP_544082.1 5040784 D 364106 CDS YP_544083.1 91214097 3993543 5041042..5041845 1 NC_007946.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5041845 deoC 3993543 deoC Escherichia coli UTI89 deoxyribose-phosphate aldolase YP_544083.1 5041042 D 364106 CDS YP_544084.2 162138298 3993544 5041923..5043245 1 NC_007946.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5043245 deoA 3993544 deoA Escherichia coli UTI89 thymidine phosphorylase YP_544084.2 5041923 D 364106 CDS YP_544085.1 91214099 3993545 5043297..5044520 1 NC_007946.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5044520 deoB 3993545 deoB Escherichia coli UTI89 phosphopentomutase YP_544085.1 5043297 D 364106 CDS YP_544086.2 162138297 3993546 5044577..5045296 1 NC_007946.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5045296 deoD 3993546 deoD Escherichia coli UTI89 purine nucleoside phosphorylase YP_544086.2 5044577 D 364106 CDS YP_544087.1 91214101 3993547 5045463..5046794 1 NC_007946.1 hypothetical protein 5046794 yjjJ 3993547 yjjJ Escherichia coli UTI89 hypothetical protein YP_544087.1 5045463 D 364106 CDS YP_544088.1 91214102 3993548 complement(5046795..5047811) 1 NC_007946.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 5047811 lplA 3993548 lplA Escherichia coli UTI89 lipoate-protein ligase A YP_544088.1 5046795 R 364106 CDS YP_544089.1 91214103 3993549 complement(5047839..5048483) 1 NC_007946.1 hypothetical protein 5048483 smp 3993549 smp Escherichia coli UTI89 hypothetical protein YP_544089.1 5047839 R 364106 CDS YP_544090.2 162138296 3993550 5048589..5049557 1 NC_007946.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5049557 serB 3993550 serB Escherichia coli UTI89 phosphoserine phosphatase YP_544090.2 5048589 D 364106 CDS YP_544091.1 91214105 3993551 5049558..5050988 1 NC_007946.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5050988 radA 3993551 radA Escherichia coli UTI89 DNA repair protein RadA YP_544091.1 5049558 D 364106 CDS YP_544092.1 91214106 3993552 5050988..5052241 1 NC_007946.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5052241 nadR 3993552 nadR Escherichia coli UTI89 nicotinamide-nucleotide adenylyltransferase YP_544092.1 5050988 D 364106 CDS YP_544093.1 91214107 3993553 5052255..5052665 1 NC_007946.1 hypothetical protein 5052665 3993553 UTI89_C5162 Escherichia coli UTI89 hypothetical protein YP_544093.1 5052255 D 364106 CDS YP_544094.1 91214108 3993554 5052667..5052951 1 NC_007946.1 hypothetical protein 5052951 3993554 UTI89_C5163 Escherichia coli UTI89 hypothetical protein YP_544094.1 5052667 D 364106 CDS YP_544095.1 91214109 3993555 complement(5053007..5054674) 1 NC_007946.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 5054674 yjjK 3993555 yjjK Escherichia coli UTI89 ABC transporter ATP-binding protein YP_544095.1 5053007 R 364106 CDS YP_544096.1 91214110 3993556 5054881..5056818 1 NC_007946.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5056818 slt 3993556 slt Escherichia coli UTI89 lytic murein transglycosylase YP_544096.1 5054881 D 364106 CDS YP_544097.1 91214111 3993557 5056908..5057234 1 NC_007946.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5057234 trpR 3993557 trpR Escherichia coli UTI89 Trp operon repressor YP_544097.1 5056908 D 364106 CDS YP_544098.1 91214112 3993558 complement(5057307..5057843) 1 NC_007946.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 5057843 yjjX 3993558 yjjX Escherichia coli UTI89 NTPase YP_544098.1 5057307 R 364106 CDS YP_544099.1 91214113 3993559 5057886..5058533 1 NC_007946.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5058533 gpmB 3993559 gpmB Escherichia coli UTI89 phosphoglycerate mutase YP_544099.1 5057886 D 364106 CDS YP_544100.1 91214114 3990249 complement(5058530..5059399) 1 NC_007946.1 right origin-binding protein 5059399 rob 3990249 rob Escherichia coli UTI89 right origin-binding protein YP_544100.1 5058530 R 364106 CDS YP_544101.1 91214115 3990250 5059610..5060083 1 NC_007946.1 hypothetical protein 5060083 creA 3990250 creA Escherichia coli UTI89 hypothetical protein YP_544101.1 5059610 D 364106 CDS YP_544102.1 91214116 3990251 5060096..5060785 1 NC_007946.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5060785 creB 3990251 creB Escherichia coli UTI89 DNA-binding response regulator CreB YP_544102.1 5060096 D 364106 CDS YP_544103.1 91214117 3990252 5060785..5062209 1 NC_007946.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5062209 creC 3990252 creC Escherichia coli UTI89 sensory histidine kinase CreC YP_544103.1 5060785 D 364106 CDS YP_544104.1 91214118 3990253 5062267..5063619 1 NC_007946.1 hypothetical protein 5063619 creD 3990253 creD Escherichia coli UTI89 hypothetical protein YP_544104.1 5062267 D 364106 CDS YP_544105.1 91214119 3990254 complement(5063679..5064395) 1 NC_007946.1 two-component response regulator 5064395 arcA 3990254 arcA Escherichia coli UTI89 two-component response regulator YP_544105.1 5063679 R 364106 CDS YP_544106.1 91214120 3990255 5064491..5064631 1 NC_007946.1 hypothetical protein 5064631 yjjY 3990255 yjjY Escherichia coli UTI89 hypothetical protein YP_544106.1 5064491 D 364106 CDS YP_544107.1 91214121 3990256 5065010..5065717 1 NC_007946.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5065717 lasT 3990256 lasT Escherichia coli UTI89 RNA methyltransferase YP_544107.1 5065010 D 364106 CDS