-- dump date 20140619_090916 -- class Genbank::CDS -- table cds_note -- id note YP_001739873.1 identified by Glimmer3; putative YP_001739874.1 identified by similarity to SP:P13658; match to protein family HMM PF03432 YP_001739875.1 identified by similarity to SP:P13657; match to protein family HMM PF05713 YP_001739876.1 identified by similarity to SP:P03051; match to protein family HMM PF01815 YP_001739877.1 identified by Glimmer3; putative YP_001739878.1 identified by similarity to GB:AAS58761.1 YP_001739879.1 identified by similarity to SP:P02985; match to protein family HMM PF03526 YP_001739880.1 identified by similarity to SP:P21178; match to protein family HMM PF01024 YP_001739881.1 identified by similarity to GB:AAB59142.1 YP_001739883.1 identified by match to protein family HMM PF01051 YP_001739884.1 identified by match to protein family HMM PF03389 YP_001739885.1 identified by similarity to SP:P07114 YP_001739886.1 identified by Glimmer3; putative YP_001739887.1 identified by Glimmer3; putative YP_001739888.1 identified by Glimmer3; putative YP_001739889.1 identified by Glimmer3; putative YP_001739891.1 RepA YP_001739892.1 identified by similarity to SP:P62537 YP_001739893.1 identified by similarity to SP:P0ACE3; match to protein family HMM PF05321 YP_001739894.1 identified by match to protein family HMM PF00565 YP_001739895.1 identified by similarity to RF:NP_958725.1 YP_001739896.1 identified by similarity to SP:P22707; match to protein family HMM PF05286 YP_001739897.1 identified by similarity to SP:P22709; match to protein family HMM PF05857; match to protein family HMM TIGR02755 YP_001739898.1 cleaves origin of transfer and unwinds; oriT relaxase YP_001739899.1 type IV secretion system coupling protein; similar to F plasmid TraD YP_001739900.1 identified by similarity to SP:P13979; match to protein family HMM PF05818 YP_001739901.1 identified by similarity to GB:ABC42218.1 YP_001739902.1 identified by similarity to SP:P33790; match to protein family HMM PF07916 YP_001739903.1 identified by similarity to SP:P15069; match to protein family HMM PF06122 YP_001739904.1 identified by similarity to SP:P18353 YP_001739905.1 identified by similarity to SP:P18035; match to protein family HMM TIGR02738 YP_001739906.1 identified by similarity to SP:P18033; match to protein family HMM TIGR02741 YP_001739907.1 identified by similarity to SP:P18034 YP_001739908.1 type IV secretion system pilus assembly protein; similar to F plasmid TraF YP_001739909.1 identified by similarity to SP:Q05807 YP_001739910.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_001739911.1 identified by similarity to SP:P18473; match to protein family HMM TIGR02742 YP_001739912.1 identified by Glimmer3; putative YP_001739913.1 identified by Glimmer3; putative YP_001739914.1 identified by similarity to SP:P18471; match to protein family HMM PF06834 YP_001739915.1 identified by similarity to SP:P18472; match to protein family HMM TIGR02743 YP_001739916.1 identified by similarity to SP:P18006; match to protein family HMM TIGR02744 YP_001739917.1 similar to VirB4 YP_001739918.1 identified by similarity to SP:P41065; match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_001739919.1 identified by similarity to SP:P41069; match to protein family HMM TIGR02747 YP_001739920.1 identified by similarity to SP:P41072 YP_001739921.1 identified by similarity to SP:P41070 YP_001739922.1 identified by similarity to SP:P41068; match to protein family HMM PF07296 YP_001739923.1 identified by similarity to SP:P41067; match to protein family HMM PF06447 YP_001739924.1 identified by similarity to SP:P41066; match to protein family HMM PF06586; match to protein family HMM TIGR02756 YP_001739925.1 identified by similarity to SP:P08322; match to protein family HMM PF05309; match to protein family HMM TIGR02761 YP_001739926.1 identified by similarity to SP:P08321; match to protein family HMM PF07178; match to protein family HMM TIGR02762 YP_001739927.1 identified by similarity to SP:P04737; match to protein family HMM PF05513; match to protein family HMM TIGR02758 YP_001739928.1 identified by similarity to SP:P05836 YP_001739929.1 identified by similarity to SP:P05837; match to protein family HMM PF00989 YP_001739930.1 identified by similarity to SP:P10026; match to protein family HMM PF05261 YP_001739931.1 identified by match to protein family HMM PF01464 YP_001739932.1 identified by Glimmer3; putative YP_001739933.1 identified by similarity to SP:P18005; match to protein family HMM PF06067 YP_001739934.1 identified by similarity to SP:Q02885 YP_001739935.1 identified by Glimmer3; putative YP_001739936.1 identified by Glimmer3; putative YP_001739937.1 identified by Glimmer3; putative YP_001739938.1 identified by similarity to SP:P11895; match to protein family HMM PF01848 YP_001739939.1 identified by Glimmer3; putative YP_001739940.1 PsiA YP_001739941.1 identified by similarity to SP:P10032; match to protein family HMM PF06290 YP_001739942.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_001739943.1 identified by similarity to SP:Q5QJF4; match to protein family HMM PF06006 YP_001739944.1 identified by similarity to SP:P28044; match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_001739945.1 identified by Glimmer3; putative YP_001739946.1 identified by similarity to GB:AAR05681.1 YP_001739947.1 identified by similarity to GB:AAR05680.1 YP_001739948.1 identified by similarity to GB:AAR05679.1 YP_001739949.1 identified by Glimmer3; putative YP_001739950.1 identified by Glimmer3; putative YP_001739951.1 identified by similarity to GB:AAS76404.1 YP_001739952.1 identified by similarity to GB:AAS76405.1 YP_001739953.1 identified by match to protein family HMM PF03230 YP_001739954.1 identified by Glimmer3; putative YP_001739955.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001739956.1 identified by similarity to SP:P03830; match to protein family HMM PF03400 YP_001739957.1 identified by similarity to GB:ABB64642.1 YP_001739958.1 identified by Glimmer3; putative YP_001739959.1 identified by Glimmer3; putative YP_001739960.1 SopB YP_001739961.1 identified by similarity to SP:P62556; match to protein family HMM PF00376; match to protein family HMM PF01656 YP_001739962.1 identified by match to protein family HMM PF03400 YP_001739963.1 identified by similarity to GB:ABB64642.1 YP_001739964.1 identified by similarity to GB:CAL13433.1 YP_001739965.1 identified by Glimmer3; putative YP_001739966.1 identified by Glimmer3; putative YP_001739967.1 identified by Glimmer3; putative YP_001739968.1 identified by Glimmer3; putative YP_001739969.1 identified by similarity to GB:AAT11267.1; similarity to GB:ABA54734.1; match to protein family HMM PF00950 YP_001739970.1 identified by similarity to GB:AAT11266.1; match to protein family HMM PF00950; match to protein family HMM PF01032 YP_001739971.1 identified by similarity to GB:AAT11265.1; match to protein family HMM PF00005 YP_001739972.1 identified by similarity to GB:AAT11264.1; match to protein family HMM PF01297 YP_001739973.1 identified by similarity to GB:ABB64642.1 YP_001739974.1 identified by match to protein family HMM PF03400 YP_001739975.1 identified by Glimmer3; putative YP_001739976.1 identified by similarity to GB:AAF94632.1; match to protein family HMM PF01527 YP_001739977.1 identified by Glimmer3; putative YP_001739978.1 identified by match to protein family HMM PF00665 YP_001739979.1 identified by Glimmer3; putative YP_001739980.1 identified by Glimmer3; putative YP_001739981.1 identified by similarity to SP:Q57154; match to protein family HMM PF01051 YP_001739982.1 identified by match to protein family HMM PF00589 YP_001739983.1 identified by match to protein family HMM PF07395 YP_001739984.1 identified by similarity to GB:AAG43374.1; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_001739985.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_001739986.1 identified by Glimmer3; putative YP_001739987.1 identified by match to protein family HMM PF01527 YP_001739988.1 identified by match to protein family HMM PF00665 YP_001739989.1 identified by similarity to GB:ABB64642.1 YP_001739990.1 identified by match to protein family HMM PF03400 YP_001739991.1 identified by Glimmer3; putative YP_001739992.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001739993.1 identified by match to protein family HMM PF00665 YP_001739994.1 identified by similarity to SP:P05820 YP_001739995.1 identified by similarity to SP:P18002 YP_001739996.1 identified by similarity to SP:P18021; match to protein family HMM PF00589 YP_001739997.1 identified by Glimmer3; putative YP_001739998.1 identified by match to protein family HMM PF00665 YP_001739999.1 identified by match to protein family HMM PF00665 YP_001740000.1 identified by match to protein family HMM PF00302 YP_001740001.1 identified by similarity to GB:ABG56838.1 YP_001740002.1 identified by match to protein family HMM PF00665 YP_001740003.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02249 YP_001740004.1 identified by similarity to SP:P11731; match to protein family HMM PF00186 YP_001740005.1 identified by match to protein family HMM PF00665 YP_001740006.1 identified by match to protein family HMM PF01526 YP_001740007.1 identified by match to protein family HMM PF02371 YP_001740008.1 identified by similarity to GB:BAF38229.1 YP_001740009.1 identified by similarity to SP:P0AC11; match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_001740010.1 identified by match to protein family HMM PF01636 YP_001740011.1 identified by match to protein family HMM PF04655 YP_001740012.1 identified by similarity to SP:P62593; match to protein family HMM PF00144 YP_001740013.1 identified by match to protein family HMM PF00665 YP_001740014.1 identified by match to protein family HMM PF00561 YP_001740015.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490 YP_001740016.1 streptomycin 3'-adenyltransferase YP_001740017.1 identified by match to protein family HMM PF00665 YP_001740018.1 identified by similarity to GB:AAR07693.1 YP_001740019.1 identified by similarity to GB:AAR07694.1 YP_001740020.1 identified by similarity to SP:Q05459; match to protein family HMM PF04014 YP_001740021.1 identified by match to protein family HMM PF01850 YP_001740022.1 identified by similarity to GB:BAB91601 YP_001740023.1 identified by similarity to GB:BAB91600 YP_001740024.1 identified by similarity to GB:BAB91599 YP_001740025.1 identified by similarity to GB:BAB91598 YP_001740026.1 identified by similarity to GB:BAB91597 YP_001740027.1 identified by match to protein family HMM PF03773 YP_001740028.1 identified by match to protein family HMM PF01022 YP_001740029.1 identified by match to protein family HMM PF00665 YP_001740030.1 identified by match to protein family HMM PF01526 YP_001740031.1 identified by similarity to GB:AAS76290 YP_001740032.1 identified by similarity to SP:P03038; match to protein family HMM PF00440; match to protein family HMM PF02909 YP_001740033.1 identified by similarity to SP:P02982; match to protein family HMM PF07690; match to protein family HMM TIGR00880 YP_001740034.1 identified by match to protein family HMM PF00892 YP_001740035.1 identified by similarity to GB:AAS76286.1 YP_001740036.1 identified by match to protein family HMM PF00665 YP_001740037.1 identified by similarity to SP:P00551; match to protein family HMM PF01636 YP_001740038.1 identified by match to protein family HMM PF00665 YP_001740039.1 identified by similarity to GB:ABB64642.1 YP_001740040.1 identified by similarity to SP:P13976; match to protein family HMM PF02452 YP_001740041.1 identified by similarity to SP:P13975; match to protein family HMM PF04014 YP_001740042.1 identified by match to protein family HMM PF02517 YP_001742118.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001742119.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001742120.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001742121.1 identified by Glimmer3; putative YP_001742122.1 identified by match to protein family HMM PF03883 YP_001742123.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_001742124.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_001742125.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001742126.1 identified by match to protein family HMM PF01184 YP_001742127.1 identified by match to protein family HMM PF03667 YP_001742129.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001742130.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001742131.1 identified by match to protein family HMM PF07135 YP_001742132.1 identified by match to protein family HMM PF00884 YP_001742133.1 identified by similarity to GB:AAX63939.1 YP_001742134.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001742135.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001742136.1 identified by match to protein family HMM PF01055 YP_001742137.1 identified by similarity to SP:P96792; match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_001742138.1 identified by Glimmer3; putative YP_001742139.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001742140.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001742141.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001742142.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001742143.1 identified by match to protein family HMM PF00254 YP_001742144.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001742145.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_001742146.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001742147.1 identified by Glimmer3; putative YP_001742148.1 identified by Glimmer3; putative YP_001742149.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001742150.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001742151.1 identified by Glimmer3; putative YP_001742152.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons YP_001742153.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_001742154.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001742155.1 identified by match to protein family HMM PF00501 YP_001742156.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001742157.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001742158.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001742159.1 identified by Glimmer3; putative YP_001742160.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001742161.1 involved in electron transfer during carnitine metabolism YP_001742162.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_001742164.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001742165.1 Required for full activity of KefC, a potassium-proton antiporter YP_001742166.1 transport system that facilitates potassium-efflux YP_001742167.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001742168.1 identified by Glimmer3; putative YP_001742170.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001742171.1 protein associated with Co2+ and Mg2+ efflux YP_001742172.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001742173.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001742174.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001742175.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001742176.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001742177.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_001742178.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001742179.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001742180.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001742181.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001742182.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001742183.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001742184.1 identified by similarity to GB:CAG77221.1 YP_001742185.1 identified by similarity to GB:AAG02753.1 YP_001742186.1 identified by match to protein family HMM PF09335 YP_001742187.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001742188.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001742189.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001742190.1 identified by similarity to GB:ABB60319.1 YP_001742191.1 activates sgrS under glucose-phosphate stress conditions YP_001742192.1 identified by similarity to GB:AAX64010.1 YP_001742193.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001742194.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001742195.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001742196.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001742197.1 identified by Glimmer3; putative YP_001742198.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_001742199.1 identified by Glimmer3; putative YP_001742200.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_001742201.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001742202.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001742203.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001742204.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_001742205.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001742206.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_001742207.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001742208.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_001742209.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001742210.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001742211.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001742212.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001742213.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001742214.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001742215.1 involved in septum formation YP_001742216.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001742217.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001742218.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001742219.1 secM translational pause allows for the initiation of secA translation YP_001742220.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001742221.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586 YP_001742222.1 identified by match to protein family HMM PF03884 YP_001742223.1 identified by match to protein family HMM PF07072 YP_001742224.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001742225.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001742226.1 identified by match to protein family HMM PF00482 YP_001742227.1 identified by match to protein family HMM PF00437 YP_001742228.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001742229.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001742230.1 identified by match to protein family HMM PF01510 YP_001742231.1 involved in regulation of beta-lactamase; putative signaling protein YP_001742232.1 identified by similarity to SP:P15993; match to protein family HMM PF00324 YP_001742233.1 identified by match to protein family HMM PF01844; match to protein family HMM PF05638; match to protein family HMM PF06958; match to protein family HMM TIGR03344 YP_001742236.1 identified by match to protein family HMM PF01320 YP_001742238.1 identified by match to protein family HMM PF01320 YP_001742239.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001742240.1 identified by Glimmer3; putative YP_001742241.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001742242.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001742243.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001742244.1 identified by similarity to GB:AAZ86919.1 YP_001742245.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001742246.1 identified by match to protein family HMM PF06062 YP_001742247.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001742248.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001742250.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001742251.1 identified by match to protein family HMM PF01011; match to protein family HMM TIGR03074 YP_001742252.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_001742253.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_001742254.1 identified by match to protein family HMM PF00005 YP_001742255.1 identified by match to protein family HMM PF01061 YP_001742256.1 identified by match to protein family HMM PF03610 YP_001742257.1 identified by match to protein family HMM PF01522 YP_001742258.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001742259.1 yadD; identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001742260.1 identified by Glimmer3; putative YP_001742261.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001742262.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001742263.1 identified by match to protein family HMM PF00419 YP_001742264.1 identified by similarity to SP:P12267 YP_001742265.1 identified by similarity to GB:AAZ86940.1 YP_001742266.1 yadM; identified by match to protein family HMM PF00419 YP_001742267.1 similar to the fimbrial usher protein PapC YP_001742268.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001742269.1 identified by match to protein family HMM PF00419 YP_001742270.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_001742271.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001742272.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001742273.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420 YP_001742274.1 Regulatory factor involved in maltose metabolism YP_001742275.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_001742276.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001742277.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001742278.1 identified by Glimmer3; putative YP_001742279.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_001742280.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001742281.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001742282.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001742283.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001742284.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001742285.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001742286.1 identified by match to protein family HMM PF03458 YP_001742287.1 solute binding component of the vitamin B12 transport system BtuCDF YP_001742288.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001742289.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001742290.1 protease Do; required at high temperature; degrades damaged proteins YP_001742291.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_001742293.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001742294.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001742295.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001742296.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001742297.1 identified by Glimmer3; putative YP_001742298.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001742299.1 Catalyzes the phosphorylation of UMP to UDP YP_001742300.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001742301.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001742302.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001742303.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001742304.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001742305.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001742306.1 identified by match to protein family HMM PF03938 YP_001742307.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001742308.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001742309.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001742310.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001742311.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001742312.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001742313.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001742314.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001742315.1 identified by match to protein family HMM PF00903 YP_001742316.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_001742317.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_001742318.1 identified by match to protein family HMM PF06786 YP_001742319.1 identified by match to protein family HMM PF07152 YP_001742320.1 identified by match to protein family HMM PF00472 YP_001742321.1 identified by match to protein family HMM PF04170 YP_001742323.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001742324.1 yaeB; identified by similarity to SP:P28634; match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_001742326.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_001742327.1 part of the MetNIQ methionine uptake system YP_001742328.1 part of the metNIQ transport system for methionine YP_001742329.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001742330.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001742331.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742332.1 identified by match to protein family HMM PF03372 YP_001742333.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001742334.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001742335.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_001742336.1 identified by match to protein family HMM PF08241 YP_001742337.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001742338.1 3'-5' exonuclease of DNA polymerase III YP_001742339.1 identified by match to protein family HMM PF00795 YP_001742340.1 inactivates vertebrate C-type lysozyme YP_001742341.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001742342.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001742343.1 identified by match to protein family HMM PF00310 YP_001742344.1 yaFK; identified by match to protein family HMM PF06104 YP_001742345.1 identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_001742346.1 identified by match to protein family HMM PF00877 YP_001742347.1 identified by similarity to GB:AAP15822.1; match to protein family HMM PF07605 YP_001742348.1 identified by similarity to GB:CAH19113.1; match to protein family HMM PF00771 YP_001742349.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001742350.1 identified by similarity to GB:CAH19115.1; match to protein family HMM PF01311; match to protein family HMM TIGR01400 YP_001742351.1 identified by similarity to GB:CAH19116.1; match to protein family HMM PF01313 YP_001742352.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001742353.1 identified by similarity to GB:CAH19118.1; match to protein family HMM PF01052 YP_001742354.1 identified by similarity to GB:CAH19119.1; match to protein family HMM PF01052 YP_001742355.1 identified by similarity to GB:CAH19120.1; match to protein family HMM PF00158; match to protein family HMM PF02954 YP_001742356.1 identified by similarity to GB:CAH19121.1; match to protein family HMM PF02049 YP_001742357.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001742358.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001742359.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001742360.1 identified by similarity to GB:CAH19125.1; match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496 YP_001742361.1 identified by similarity to GB:CAH19126.1; match to protein family HMM TIGR02473 YP_001742362.1 identified by similarity to GB:CAH19127.1; match to protein family HMM PF01467; match to protein family HMM PF06574; match to protein family HMM TIGR00125 YP_001742363.1 identified by Glimmer3; putative YP_001742364.1 identified by Glimmer3; putative YP_001742365.1 identified by similarity to GB:CAH19128.1; match to protein family HMM PF00535 YP_001742366.1 identified by similarity to GB:CAH19129.1 YP_001742367.1 identified by similarity to GB:CAH19130.1 YP_001742368.1 identified by similarity to GB:CAH19131.1; match to protein family HMM PF04316 YP_001742369.1 identified by similarity to GB:CAH19132.1; match to protein family HMM PF08666; match to protein family HMM TIGR03170 YP_001742370.1 identified by similarity to GB:CAH19133.1; match to protein family HMM TIGR01396 YP_001742371.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001742372.1 identified by similarity to GB:CAH19135.1; match to protein family HMM PF03963 YP_001742373.1 identified by similarity to GB:CAH19136.1; match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM PF07559 YP_001742374.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001742375.1 makes up the distal portion of the flagellar basal body rod YP_001742376.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH YP_001742377.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001742378.1 identified by similarity to GB:CAH19141.1 YP_001742379.1 identified by similarity to GB:CAH19142.1; match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM TIGR02492 YP_001742380.1 identified by similarity to GB:CAH19143.1; match to protein family HMM PF00669; match to protein family HMM TIGR02550 YP_001742381.1 identified by similarity to GB:CAH19144.1 YP_001742382.1 identified by similarity to GB:CAH19147.1; match to protein family HMM PF00486 YP_001742383.1 identified by similarity to GB:CAH19148.1; match to protein family HMM PF00669; match to protein family HMM PF00700 YP_001742384.1 identified by similarity to GB:CAH19149.1; match to protein family HMM PF02465; match to protein family HMM PF07195 YP_001742385.1 identified by similarity to GB:CAH19150.1; match to protein family HMM PF02561; match to protein family HMM TIGR00208 YP_001742386.1 identified by similarity to GB:CAH19151.1 YP_001742387.1 identified by similarity to GB:CAH19152.1; match to protein family HMM PF02120 YP_001742388.1 identified by similarity to GB:CAH19153.1; match to protein family HMM PF03748 YP_001742389.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001742390.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001742391.1 identified by similarity to GB:CAH19156.1; match to protein family HMM PF00691 YP_001742392.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001742393.1 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552 YP_001742394.1 yafP; identified by match to protein family HMM PF00583 YP_001742395.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_001742396.1 similar to release factor 1 and 2 YP_001742397.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_001742398.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001742399.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001742400.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001742401.1 identified by match to protein family HMM PF00267 YP_001742402.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001742403.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001742404.1 identified by match to protein family HMM PF00589 YP_001742405.1 identified by similarity to GB:BAA16614.1 YP_001742406.1 identified by similarity to GB:CAD73582.1 YP_001742407.1 identified by match to protein family HMM PF00072 YP_001742408.1 identified by Glimmer3; putative YP_001742409.1 identified by match to protein family HMM PF01527 YP_001742410.1 identified by match to protein family HMM PF00665 YP_001742411.1 identified by match to protein family HMM PF03230 YP_001742412.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001742413.1 identified by similarity to GB:ABB61177.1; match to protein family HMM PF06174 YP_001742414.1 identified by similarity to SP:P52141; match to protein family HMM PF06154 YP_001742415.1 identified by Glimmer3; putative YP_001742416.1 identified by Glimmer3; putative YP_001742417.1 identified by match to protein family HMM PF07274 YP_001742418.1 identified by Glimmer3; putative YP_001742424.1 identified by match to protein family HMM PF00196 YP_001742425.1 identified by Glimmer3; putative YP_001742426.1 identified by Glimmer3; putative YP_001742427.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001742428.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001742429.1 identified by match to protein family HMM PF00724 YP_001742430.1 identified by similarity to GB:AAZ61189.1 YP_001742431.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742432.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742433.1 identified by match to protein family HMM PF00248 YP_001742434.1 identified by similarity to GB:ABB80491.1; match to protein family HMM PF00248 YP_001742435.1 identified by match to protein family HMM PF02369 YP_001742436.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_001742437.1 identified by match to protein family HMM PF00248 YP_001742438.1 identified by match to protein family HMM PF04224 YP_001742439.1 identified by match to protein family HMM PF07338 YP_001742440.1 Involved in disulfide oxidoreductase activity and electron transport YP_001742441.1 identified by match to protein family HMM PF00165 YP_001742442.1 identified by match to protein family HMM PF02754 YP_001742443.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_001742444.1 identified by match to protein family HMM PF02589 YP_001742445.1 identified by Glimmer3; putative YP_001742446.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001742447.1 catalyzes the formation of betaine from betaine aldehyde YP_001742448.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001742449.1 proton-motive-force-driven choline transporter YP_001742450.1 identified by match to protein family HMM PF00196; match to protein family HMM PF00563 YP_001742451.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742452.1 identified by match to protein family HMM PF06496 YP_001742453.1 identified by match to protein family HMM PF00023 YP_001742455.1 identified by match to protein family HMM PF06263 YP_001742456.1 identified by match to protein family HMM PF06545 YP_001742457.1 identified by match to protein family HMM PF00696 YP_001742458.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_001742459.1 identified by Glimmer3; putative YP_001742460.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001742462.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001742463.1 identified by match to protein family HMM PF07338 YP_001742464.1 identified by Glimmer3; putative YP_001742465.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329 YP_001742466.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001742467.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001742468.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001742469.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_001742470.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_001742471.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001742472.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_001742473.1 identified by match to protein family HMM PF00484 YP_001742474.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001742475.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_001742476.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown YP_001742477.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001742478.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001742479.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_001742480.1 activator of 3-phenylpropionic acid catabolism YP_001742481.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_001742482.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family YP_001742483.1 identified by match to protein family HMM PF00561 YP_001742484.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_001742485.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001742486.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001742487.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895 YP_001742489.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_001742490.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_001742491.1 formaldehyde-induced negative regulator of the frmRAB operon YP_001742492.1 identified by Glimmer3; putative YP_001742493.1 identified by match to protein family HMM PF00132 YP_001742494.1 identified by match to protein family HMM PF00535 YP_001742495.1 identified by match to protein family HMM PF02585 YP_001742497.1 with TauB and TauC is responsible for taurine uptake. YP_001742498.1 Part of the ABC transporter complex tauABC involved in taurine import YP_001742499.1 identified by match to protein family HMM PF00528 YP_001742500.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001742501.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001742502.1 yaiT YP_001742503.1 identified by match to protein family HMM PF00665 YP_001742504.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001742505.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001742506.1 identified by Glimmer3; putative YP_001742507.1 this protein has no known enzymatic function YP_001742508.1 identified by Glimmer3; putative YP_001742509.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001742510.1 identified by match to protein family HMM PF07759 YP_001742513.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001742514.1 identified by Glimmer3; putative YP_001742516.1 identified by match to protein family HMM PF00245 YP_001742517.1 identified by match to protein family HMM PF07769 YP_001742518.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis YP_001742519.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001742520.1 identified by match to protein family HMM PF02639 YP_001742521.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001742523.1 identified by match to protein family HMM PF07302 YP_001742524.1 identified by match to protein family HMM PF06865 YP_001742525.1 identified by Glimmer3; putative YP_001742526.1 Required for efficient pilin antigenic variation YP_001742527.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001742528.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_001742529.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_001742530.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001742531.1 identified by Glimmer3; putative YP_001742532.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_001742533.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001742535.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_001742536.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001742537.1 identified by match to protein family HMM PF00128 YP_001742538.1 identified by Glimmer3; putative YP_001742539.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_001742540.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001742541.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001742542.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001742543.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001742544.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001742545.1 identified by match to protein family HMM PF03693; match to protein family HMM TIGR02606 YP_001742546.1 identified by match to protein family HMM PF05016 YP_001742547.1 identified by match to protein family HMM PF01844 YP_001742548.1 identified by match to protein family HMM PF03502 YP_001742549.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001742550.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_001742551.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_001742552.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001742553.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001742554.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001742555.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001742556.1 identified by match to protein family HMM PF00248 YP_001742557.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001742558.1 identified by match to protein family HMM PF00348 YP_001742559.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001742560.1 Required for the synthesis of the thiazole moiety YP_001742561.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_001742562.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001742563.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001742564.1 identified by match to protein family HMM PF07690 YP_001742565.1 identified by Glimmer3; putative YP_001742566.1 identified by match to protein family HMM PF08238 YP_001742567.1 identified by match to protein family HMM PF00583 YP_001742568.1 identified by match to protein family HMM PF08681 YP_001742569.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001742570.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02847 YP_001742571.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842 YP_001742572.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843 YP_001742573.1 identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433 YP_001742574.1 identified by Glimmer3; putative YP_001742575.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001742576.1 identified by match to protein family HMM PF03923 YP_001742577.1 identified by Glimmer3; putative YP_001742578.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001742579.1 identified by Glimmer3; putative YP_001742580.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001742581.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001742582.1 binds and unfolds substrates as part of the ClpXP protease YP_001742583.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_001742584.1 histone-like DNA-binding protein YP_001742585.1 identified by match to protein family HMM PF00639; match to protein family HMM PF09312 YP_001742586.1 identified by match to protein family HMM TIGR00426 YP_001742587.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_001742588.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001742589.1 identified by match to protein family HMM PF00496 YP_001742590.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001742591.1 identified by match to protein family HMM PF01037 YP_001742592.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001742593.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001742594.1 identified by Glimmer3; putative YP_001742595.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001742596.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_001742597.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189 YP_001742599.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_001742600.1 identified by match to protein family HMM PF07237 YP_001742601.1 identified by match to protein family HMM PF00563 YP_001742603.1 identified by match to protein family HMM PF00132 YP_001742604.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_001742606.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001742607.1 identified by similarity to SP:P0AE06; match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001742608.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001742609.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001742611.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_001742612.1 identified by match to protein family HMM PF04304 YP_001742613.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001742614.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001742615.1 ybaB; identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_001742616.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001742617.1 molecular chaperone YP_001742618.1 identified by Glimmer3; putative YP_001742619.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001742620.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001742621.1 identified by match to protein family HMM PF07859 YP_001742622.1 identified by match to protein family HMM PF00294 YP_001742623.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001742624.1 identified by match to protein family HMM PF07690 YP_001742625.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001742626.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_001742627.1 identified by match to protein family HMM PF07446 YP_001742628.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_001742629.1 catalyzes the formation of glutamate from glutamine YP_001742630.1 identified by match to protein family HMM PF00324; match to protein family HMM PF01490; match to protein family HMM PF03845 YP_001742631.1 activator of copper-responsive regulon genes YP_001742632.1 identified by Glimmer3; putative YP_001742633.1 identified by similarity to GB:CAL11950.1 YP_001742634.1 identified by match to protein family HMM PF03895 YP_001742635.1 identified by Glimmer3; putative YP_001742636.1 identified by Glimmer3; putative YP_001742637.1 identified by similarity to GB:ABB60623.1 YP_001742638.1 identified by match to protein family HMM PF01957 YP_001742639.1 identified by match to protein family HMM PF01145 YP_001742640.1 identified by match to protein family HMM PF00005 YP_001742641.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_001742642.1 identified by match to protein family HMM PF00085 YP_001742643.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001742644.1 identified by match to protein family HMM PF00657 YP_001742645.1 identified by match to protein family HMM PF00005 YP_001742646.1 identified by match to protein family HMM PF02687 YP_001742647.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001742648.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_001742649.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001742650.1 regulates operons involved in the utilization of allantoin YP_001742651.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001742652.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234 YP_001742653.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505 YP_001742654.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_001742655.1 Plays a crucial role on both purine and pyrimidine metabolism YP_001742656.1 identified by similarity to GB:ABD51571.1 YP_001742657.1 identified by match to protein family HMM PF03400 YP_001742658.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001742659.1 identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214 YP_001742660.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001742661.1 identified by match to protein family HMM PF02615; match to protein family HMM TIGR03175 YP_001742662.1 multicopy suppressor of dominant negative ftsH mutations YP_001742663.1 identified by match to protein family HMM PF06545 YP_001742665.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746 YP_001742666.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001742667.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_001742668.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001742669.1 identified by match to protein family HMM PF00160 YP_001742670.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001742671.1 identified by match to protein family HMM PF04307 YP_001742673.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001742674.1 identified by match to protein family HMM PF00419 YP_001742675.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001742676.1 identified by similarity to SP:P77468; match to protein family HMM PF00577 YP_001742679.1 activates the production of the major fimbrae protein FimA YP_001742680.1 identified by Glimmer3; putative YP_001742681.1 identified by match to protein family HMM PF00165 YP_001742683.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001742684.1 identified by similarity to SP:P0AFA5; match to protein family HMM PF05157 YP_001742685.1 identified by similarity to SP:Q8FK37; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_001742686.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001742687.1 identified by Glimmer3; putative YP_001742688.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001742690.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001742691.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914 YP_001742692.1 identified by match to protein family HMM PF00324 YP_001742693.1 identified by match to protein family HMM PF00924 YP_001742694.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001742695.1 identified by match to protein family HMM PF04237 YP_001742696.1 identified by match to protein family HMM PF06643 YP_001742697.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_001742698.1 identified by match to protein family HMM PF01848 YP_001742699.1 identified by match to protein family HMM PF01648 YP_001742700.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001742701.1 identified by Glimmer3; putative YP_001742702.1 identified by match to protein family HMM PF00756 YP_001742703.1 identified by match to protein family HMM PF03621 YP_001742704.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_001742705.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_001742706.1 with FepBDE is involved in the transport of ferric enterobactin YP_001742707.1 with FepBCD is involved in the transport of ferric enterobactin YP_001742708.1 with FepBCG is involved in the transport of ferric enterobactin YP_001742709.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_001742710.1 with FepCDG is involved in the transport of ferric enterobactin YP_001742711.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_001742712.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_001742713.1 identified by similarity to SP:P0ADI4; match to protein family HMM PF00550; match to protein family HMM PF00857 YP_001742714.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_001742715.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001742716.1 identified by match to protein family HMM PF02554 YP_001742717.1 identified by match to protein family HMM PF04328 YP_001742718.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_001742719.1 catalyzes the transfer of an amino moiety YP_001742720.1 identified by similarity to GB:AAM53134.1; match to protein family HMM PF02195 YP_001742721.1 identified by match to protein family HMM PF01507 YP_001742722.1 identified by match to protein family HMM PF00126 YP_001742723.1 Involved in disulfide bond formation YP_001742724.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_001742725.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140 YP_001742726.1 identified by match to protein family HMM PF00582 YP_001742727.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001742728.1 identified by match to protein family HMM PF00445 YP_001742729.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_001742730.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_001742731.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_001742732.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_001742733.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_001742734.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_001742735.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_001742736.1 identified by match to protein family HMM PF02518 YP_001742737.1 regulates the expression of citAB in citrate fermentation YP_001742738.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_001742739.1 identified by match to protein family HMM PF01609 YP_001742740.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001742741.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001742742.1 identified by match to protein family HMM PF00795 YP_001742743.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001742744.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001742745.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742746.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001742747.1 identified by match to protein family HMM PF04359 YP_001742748.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_001742749.1 identified by match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413 YP_001742750.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210 YP_001742751.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_001742752.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001742753.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_001742754.1 identified by similarity to SP:P52086; match to protein family HMM PF00300; match to protein family HMM TIGR03162 YP_001742755.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001742756.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001742757.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_001742758.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001742759.1 identified by match to protein family HMM PF07295 YP_001742760.1 identified by Glimmer3; putative YP_001742761.1 identified by Glimmer3; putative YP_001742762.1 identified by match to protein family HMM PF06889 YP_001742763.1 identified by match to protein family HMM PF00226 YP_001742764.1 identified by match to protein family HMM PF08238 YP_001742765.1 identified by match to protein family HMM PF06889 YP_001742766.1 identified by match to protein family HMM PF00226 YP_001742767.1 identified by match to protein family HMM PF00012 YP_001742768.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001742769.1 identified by match to protein family HMM PF00005 YP_001742770.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001742771.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001742772.1 identified by match to protein family HMM PF00497 YP_001742773.1 identified by Glimmer3; putative YP_001742774.1 identified by Glimmer3; putative YP_001742775.1 Transfers the fatty acyl group on membrane lipoproteins YP_001742776.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471 YP_001742777.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_001742778.1 identified by match to protein family HMM PF02562 YP_001742779.1 identified by Glimmer3; putative YP_001742780.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001742781.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001742782.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001742784.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460 YP_001742785.1 identified by match to protein family HMM PF00480 YP_001742786.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001742787.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001742788.1 identified by Glimmer3; putative YP_001742789.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001742790.1 identified by Glimmer3; putative YP_001742791.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001742792.1 identified by match to protein family HMM PF03573 YP_001742794.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001742795.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001742796.1 identified by match to protein family HMM PF01402 YP_001742797.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819 YP_001742798.1 negative modulator of the initiation of chromosome replication YP_001742799.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001742800.1 YbfP YP_001742801.1 identified by similarity to GB:ABB11945.1 YP_001742802.1 identified by Glimmer3; putative YP_001742803.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001742804.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001742805.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_001742806.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001742807.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001742808.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001742809.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001742811.1 identified by match to protein family HMM PF08349 YP_001742812.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001742813.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_001742814.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_001742815.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_001742816.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_001742817.1 identified by match to protein family HMM PF03746 YP_001742818.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_001742819.1 identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082 YP_001742820.1 identified by similarity to GB:AAZ87425.1 YP_001742821.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001742822.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970 YP_001742823.1 identified by match to protein family HMM TIGR02968 YP_001742824.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001742825.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001742826.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001742827.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001742828.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001742829.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001742830.1 identified by similarity to GB:ABM24414.1 YP_001742831.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742832.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001742833.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001742834.1 identified by similarity to SP:P24943; match to protein family HMM PF00375 YP_001742835.1 identified by similarity to GB:CAL14063.1 YP_001742837.1 identified by match to protein family HMM PF05034; match to protein family HMM PF07476; match to protein family HMM TIGR01502 YP_001742838.1 identified by match to protein family HMM PF06368; match to protein family HMM TIGR01503 YP_001742839.1 identified by similarity to GB:BAB34186.1; match to protein family HMM TIGR01319 YP_001742840.1 converts methylaspartate to L-glutamate YP_001742841.1 identified by Glimmer3; putative YP_001742842.1 identified by Glimmer3; putative YP_001742843.1 identified by match to protein family HMM PF01654 YP_001742844.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_001742845.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106 YP_001742846.1 identified by match to protein family HMM TIGR02112 YP_001742847.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001742848.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001742849.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001742850.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001742851.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001742852.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802 YP_001742853.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001742854.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001742855.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_001742857.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001742858.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001742859.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_001742860.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001742861.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001742862.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_001742863.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001742864.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001742866.1 with ModCB is involved in the high-affinity transport of molybdate YP_001742867.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001742868.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001742869.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001742870.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_001742871.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001742872.1 identified by match to protein family HMM PF04303 YP_001742873.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_001742874.1 identified by match to protein family HMM PF00330; match to protein family HMM PF00694 YP_001742875.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_001742876.1 YbhB; similar to rat and human kinase inhibitory proteins YP_001742877.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001742878.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433 YP_001742879.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001742880.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_001742881.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001742882.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001742883.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_001742884.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001742885.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667 YP_001742886.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001742887.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001742888.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001742889.1 identified by match to protein family HMM PF01027 YP_001742890.1 identified by match to protein family HMM PF01027 YP_001742892.1 identified by match to protein family HMM PF00614 YP_001742893.1 identified by match to protein family HMM PF03372 YP_001742895.1 identified by match to protein family HMM PF01061 YP_001742896.1 identified by match to protein family HMM PF01061 YP_001742897.1 identified by match to protein family HMM PF00005 YP_001742898.1 identified by match to protein family HMM PF00529 YP_001742899.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209 YP_001742900.1 this helicase is not essential cell growth YP_001742902.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_001742903.1 helicase involved in DNA repair and perhaps also replication YP_001742904.1 identified by match to protein family HMM PF02885 YP_001742905.1 identified by match to protein family HMM PF02615 YP_001742906.1 identified by match to protein family HMM PF07338 YP_001742907.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_001742908.1 identified by match to protein family HMM PF03171 YP_001742909.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_001742910.1 identified by match to protein family HMM PF07338 YP_001742911.1 identified by match to protein family HMM PF05971 YP_001742912.1 identified by match to protein family HMM PF00924 YP_001742913.1 similar to ATP-binding component of ABC transporters YP_001742914.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001742915.1 similar to periplasmic-binding component of ABC transporters YP_001742916.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001742917.1 identified by match to protein family HMM PF00892 YP_001742918.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001742919.1 identified by match to protein family HMM PF00884 YP_001742921.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_001742922.1 identified by match to protein family HMM PF03600 YP_001742923.1 identified by match to protein family HMM PF03734 YP_001742924.1 identified by match to protein family HMM PF00005 YP_001742925.1 identified by Glimmer3; putative YP_001742926.1 identified by match to protein family HMM PF07350 YP_001742927.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001742928.1 identified by similarity to SP:P75793; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_001742929.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001742930.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001742931.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001742932.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001742933.1 identified by match to protein family HMM PF01112 YP_001742934.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_001742935.1 identified by match to protein family HMM PF00496 YP_001742936.1 identified by match to protein family HMM PF00528 YP_001742937.1 identified by match to protein family HMM PF00528 YP_001742938.1 identified by match to protein family HMM PF00563 YP_001742939.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001742940.1 identified by match to protein family HMM PF01381 YP_001742941.1 identified by match to protein family HMM PF06296 YP_001742942.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001742943.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001742944.1 identified by match to protein family HMM PF07995 YP_001742945.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001742946.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001742947.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_001742948.1 ybjG; identified by similarity to SP:P75806; match to protein family HMM PF01569 YP_001742949.1 identified by match to protein family HMM PF07690 YP_001742951.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001742952.1 identified by match to protein family HMM PF07690 YP_001742953.1 identified by match to protein family HMM PF00440 YP_001742954.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_001742956.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001742957.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001742958.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001742959.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_001742961.1 identified by Glimmer3; putative YP_001742962.1 identified by match to protein family HMM PF01547 YP_001742963.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001742964.1 identified by match to protein family HMM PF00528 YP_001742965.1 identified by match to protein family HMM PF00528 YP_001742967.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001742968.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001742969.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001742970.1 with ArtPMJI transports arginine across the inner membrane YP_001742971.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001742972.1 With ArtMQJI transports arginine across the inner membrane YP_001742973.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_001742975.1 identified by match to protein family HMM PF01906 YP_001742976.1 identified by similarity to SP:P75820; match to protein family HMM PF01510 YP_001742977.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_001742978.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368 YP_001742979.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_001742980.1 catalyzes the formation of acetate from pyruvate YP_001742981.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001742982.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001742983.1 identified by match to protein family HMM PF03956 YP_001742984.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001742985.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001742986.1 identified by match to protein family HMM PF00106 YP_001742987.1 identified by Glimmer3; putative YP_001742988.1 identified by match to protein family HMM PF09335 YP_001742989.1 identified by match to protein family HMM PF06930 YP_001742990.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001742991.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001742992.1 identified by match to protein family HMM PF00933; match to protein family HMM PF01915 YP_001742993.1 identified by match to protein family HMM PF04069 YP_001742994.1 identified by match to protein family HMM PF00528 YP_001742995.1 identified by match to protein family HMM PF00005 YP_001742996.1 identified by match to protein family HMM PF00528 YP_001742997.1 identified by similarity to SP:P33358; match to protein family HMM PF00376 YP_001742998.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_001742999.1 unknown function; when overproduced it confers drug-resistance YP_001743000.1 identified by match to protein family HMM PF07308 YP_001743001.1 identified by match to protein family HMM PF06998 YP_001743002.1 identified by match to protein family HMM PF04434 YP_001743003.1 identified by match to protein family HMM PF00092; match to protein family HMM PF05762 YP_001743005.1 identified by match to protein family HMM PF07728 YP_001743006.1 identified by Glimmer3; putative YP_001743008.1 identified by similarity to SP:P33345; match to protein family HMM PF05406 YP_001743009.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001743011.1 identified by similarity to GB:AAP17529.1 YP_001743012.1 identified by match to protein family HMM PF00419 YP_001743013.1 yehB; identified by match to protein family HMM PF00577 YP_001743016.1 membrane protein conferring nickel and cobalt resistance YP_001743017.1 identified by match to protein family HMM PF02583 YP_001743018.1 identified by match to protein family HMM PF00589 YP_001743019.1 identified by similarity to GB:CAG74537.1 YP_001743020.1 identified by match to protein family HMM PF05930 YP_001743021.1 identified by similarity to GB:AAZ87612.1 YP_001743022.1 identified by Glimmer3; putative YP_001743023.1 identified by Glimmer3; putative YP_001743024.1 identified by similarity to GB:AAZ87613.1 YP_001743025.1 identified by match to protein family HMM PF03288; match to protein family HMM PF08706 YP_001743026.1 identified by similarity to GB:AAZ87617.1 YP_001743027.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_001743028.1 identified by similarity to GB:ABF03362.1 YP_001743030.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554 YP_001743031.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543 YP_001743032.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_001743033.1 identified by match to protein family HMM PF05135; match to protein family HMM TIGR01560 YP_001743034.1 identified by match to protein family HMM PF01844 YP_001743035.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558 YP_001743036.1 identified by match to protein family HMM PF03354 YP_001743037.1 identified by similarity to RF:NP_836846.1 YP_001743038.1 identified by Glimmer3; putative YP_001743039.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_001743040.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001743041.1 identified by match to protein family HMM PF01183 YP_001743042.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM PF08279 YP_001743043.1 identified by match to protein family HMM PF00294 YP_001743044.1 identified by match to protein family HMM PF03747 YP_001743045.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001743046.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001743047.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001743048.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_001743049.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001743050.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001743051.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_001743052.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_001743053.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_001743054.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001743056.1 identified by match to protein family HMM PF01136 YP_001743057.1 identified by match to protein family HMM PF05016 YP_001743058.1 identified by match to protein family HMM PF01402; match to protein family HMM PF03693; match to protein family HMM TIGR02606 YP_001743059.1 identified by match to protein family HMM PF07411 YP_001743060.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001743061.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001743062.1 identified by match to protein family HMM PF07690 YP_001743063.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001743064.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001743065.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001743066.1 identified by match to protein family HMM PF00092 YP_001743068.1 identified by Glimmer3; putative YP_001743071.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_001743072.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction YP_001743073.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001743074.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001743075.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001743076.1 identified by match to protein family HMM PF01381 YP_001743077.1 identified by match to protein family HMM PF05973 YP_001743078.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_001743079.1 identified by match to protein family HMM PF02563 YP_001743080.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis YP_001743081.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_001743082.1 identified by match to protein family HMM PF00535 YP_001743083.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium YP_001743085.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_001743086.1 identified by match to protein family HMM PF00535 YP_001743087.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_001743088.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472 YP_001743089.1 identified by match to protein family HMM PF01370; match to protein family HMM PF04321 YP_001743090.1 identified by match to protein family HMM PF00293 YP_001743091.1 identified by match to protein family HMM PF00534 YP_001743092.1 identified by similarity to SP:P24174; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_001743093.1 identified by similarity to SP:P24175; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_001743094.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_001743095.1 identified by match to protein family HMM PF01943 YP_001743096.1 identified by match to protein family HMM PF04230 YP_001743097.1 identified by match to protein family HMM PF00534 YP_001743098.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_001743099.1 identified by similarity to SP:Q8X7P7; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_001743100.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001743101.1 identified by match to protein family HMM PF00535 YP_001743102.1 identified by Glimmer3; putative YP_001743103.1 identified by match to protein family HMM PF00535 YP_001743105.1 identified by match to protein family HMM PF00534 YP_001743106.1 identified by match to protein family HMM PF01943 YP_001743109.1 identified by match to protein family HMM PF03400 YP_001743110.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001743111.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_001743112.1 identified by match to protein family HMM PF02706 YP_001743113.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001743114.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001743115.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001743116.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001743117.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001743118.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001743119.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001743120.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001743121.1 identified by Glimmer3; putative YP_001743122.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_001743123.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743124.1 identified by match to protein family HMM PF00324 YP_001743125.1 identified by Glimmer3; putative YP_001743126.1 identified by match to protein family HMM PF04143 YP_001743127.1 identified by match to protein family HMM PF01206 YP_001743128.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001743129.1 identified by Glimmer3; putative YP_001743130.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001743131.1 identified by match to protein family HMM PF06445 YP_001743133.1 identified by Glimmer3; putative YP_001743134.1 identified by match to protein family HMM PF04363 YP_001743135.1 identified by similarity to SP:Q8X8U4 YP_001743138.1 identified by match to protein family HMM PF06755 YP_001743139.1 identified by match to protein family HMM PF06154 YP_001743140.1 identified by match to protein family HMM PF06174 YP_001743141.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001743142.1 identified by match to protein family HMM PF03230 YP_001743143.1 identified by match to protein family HMM PF06067 YP_001743144.1 identified by Glimmer3; putative YP_001743145.1 identified by Glimmer3; putative YP_001743146.1 identified by Glimmer3; putative YP_001743147.1 identified by match to protein family HMM PF01734 YP_001743148.1 identified by similarity to GB:AAP18661.1 YP_001743149.1 identified by similarity to GB:AAZ90778.1 YP_001743150.1 identified by match to protein family HMM PF01926 YP_001743151.1 identified by Glimmer3; putative YP_001743153.1 identified by match to protein family HMM PF00665 YP_001743155.1 identified by match to protein family HMM PF05930 YP_001743158.1 identified by match to protein family HMM PF01610 YP_001743159.1 identified by match to protein family HMM PF02126 YP_001743160.1 identified by match to protein family HMM PF04657 YP_001743161.1 identified by similarity to GB:CAD08081.1; match to protein family HMM PF07090 YP_001743162.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08220; match to protein family HMM PF08279; match to protein family HMM PF08543 YP_001743163.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001743164.1 identified by match to protein family HMM PF00665 YP_001743165.1 identified by match to protein family HMM PF00206 YP_001743166.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001743167.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_001743168.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743169.1 identified by Glimmer3; putative YP_001743170.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893 YP_001743171.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001743172.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001743173.1 identified by similarity to SP:P31459; match to protein family HMM PF05035 YP_001743174.1 identified by similarity to SP:P31460; match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001743175.1 identified by Glimmer3; putative YP_001743176.1 identified by match to protein family HMM PF01527 YP_001743177.1 identified by match to protein family HMM PF00665 YP_001743178.1 identified by Glimmer3; putative YP_001743179.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001743180.1 identified by match to protein family HMM PF00532 YP_001743181.1 identified by match to protein family HMM PF01156 YP_001743182.1 identified by match to protein family HMM PF02308 YP_001743183.1 identified by similarity to GB:AAK03301.1 YP_001743184.1 identified by match to protein family HMM PF01112 YP_001743186.1 identified by similarity to SP:P0ABP3; match to protein family HMM PF03606; match to protein family HMM PF06808; match to protein family HMM TIGR00771 YP_001743187.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001743188.1 identified by match to protein family HMM PF00206 YP_001743189.1 identified by similarity to SP:P0ABN5; match to protein family HMM PF03600; match to protein family HMM PF03605; match to protein family HMM TIGR00770 YP_001743190.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001743191.1 identified by match to protein family HMM PF00072 YP_001743192.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001743193.1 identified by match to protein family HMM PF03600; match to protein family HMM PF03605; match to protein family HMM TIGR00770 YP_001743194.1 identified by match to protein family HMM PF03600; match to protein family HMM PF03605; match to protein family HMM TIGR00770 YP_001743195.1 identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838 YP_001743196.1 identified by Glimmer3; putative YP_001743197.1 identified by similarity to GB:AAM53133.1; match to protein family HMM PF01507 YP_001743198.1 identified by Glimmer3; putative YP_001743201.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001743202.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001743203.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001743204.1 identified by match to protein family HMM PF03734 YP_001743205.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_001743206.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_001743207.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001743208.1 identified by Glimmer3; putative YP_001743209.1 yeeN; identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001743210.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001743211.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001743213.1 yeeJ; identified by match to protein family HMM PF00801; match to protein family HMM PF02369 YP_001743214.1 identified by match to protein family HMM PF06167 YP_001743215.1 identified by match to protein family HMM PF00589 YP_001743216.1 identified by similarity to GB:ABI42016.1 YP_001743217.1 identified by match to protein family HMM PF00929; match to protein family HMM PF06630 YP_001743218.1 identified by match to protein family HMM PF07358 YP_001743219.1 identified by match to protein family HMM PF05358 YP_001743220.1 identified by Glimmer3; putative YP_001743221.1 identified by Glimmer3; putative YP_001743222.1 ydfB; identified by Glimmer3; putative YP_001743223.1 identified by match to protein family HMM PF07151 YP_001743225.1 identified by match to protein family HMM PF06254 YP_001743228.1 identified by match to protein family HMM PF07789 YP_001743229.1 identified by similarity to GB:CAD05604.1; match to protein family HMM PF06163 YP_001743230.1 identified by similarity to GB:ABE56533.1 YP_001743231.1 identified by similarity to GB:AAK28855.1 YP_001743232.1 identified by similarity to GB:ABF03554.1 YP_001743233.1 identified by Glimmer3; putative YP_001743234.1 identified by similarity to GB:BAB93828.1 YP_001743235.1 identified by similarity to GB:ABF04172.1 YP_001743236.1 identified by Glimmer3; putative YP_001743238.1 identified by Glimmer3; putative YP_001743239.1 identified by match to protein family HMM PF06914 YP_001743240.1 identified by match to protein family HMM PF05866 YP_001743241.1 identified by similarity to SP:P13870; match to protein family HMM PF06323 YP_001743242.1 identified by match to protein family HMM PF04971 YP_001743243.1 ydfR; identified by match to protein family HMM PF07041 YP_001743244.1 identified by match to protein family HMM PF00959 YP_001743245.1 identified by match to protein family HMM PF03245 YP_001743246.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558 YP_001743247.1 identified by match to protein family HMM PF03354 YP_001743248.1 identified by similarity to GB:AAZ89395.1 YP_001743249.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_001743250.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543 YP_001743251.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554 YP_001743252.1 identified by similarity to GB:ABF02516.1 YP_001743253.1 identified by similarity to GB:AAL89415.1 YP_001743254.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725 YP_001743255.1 identified by similarity to GB:ABP60903.1 YP_001743256.1 identified by similarity to GB:AAF31091.1 YP_001743257.1 identified by match to protein family HMM PF06222 YP_001743258.1 identified by similarity to GB:AAL40287.1 YP_001743259.1 identified by match to protein family HMM TIGR01541; match to protein family HMM TIGR02675 YP_001743260.1 identified by match to protein family HMM PF05939 YP_001743261.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_001743262.1 identified by match to protein family HMM PF00877 YP_001743263.1 identified by match to protein family HMM PF06805 YP_001743264.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_001743265.1 identified by match to protein family HMM PF06316 YP_001743266.1 identified by match to protein family HMM PF08400 YP_001743267.1 identified by similarity to SP:P51026 YP_001743268.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001743269.1 identified by similarity to GB:BAB97540.1 YP_001743270.1 identified by Glimmer3; putative YP_001743271.1 identified by Glimmer3; putative YP_001743272.1 identified by match to protein family HMM PF01292 YP_001743273.1 identified by match to protein family HMM PF09223 YP_001743274.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001743275.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001743276.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_001743277.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_001743278.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_001743279.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_001743280.1 identified by Glimmer3; putative YP_001743281.1 identified by Glimmer3; putative YP_001743282.1 identified by similarity to SP:P77747; match to protein family HMM PF00267 YP_001743284.1 identified by match to protein family HMM PF01966 YP_001743285.1 identified by similarity to SP:P0AED9; match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_001743286.1 identified by match to protein family HMM PF03852; match to protein family HMM TIGR00632 YP_001743287.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001743288.1 identified by match to protein family HMM PF05661 YP_001743290.1 yedQ; identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743291.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001743294.1 identified by match to protein family HMM PF00196 YP_001743295.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001743296.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001743297.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001743298.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus YP_001743299.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001743300.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001743301.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001743302.1 identified by match to protein family HMM PF02120 YP_001743303.1 rod/hook and filament chaperone YP_001743304.1 involved in type III protein export during flagellum assembly YP_001743305.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001743306.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001743307.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001743308.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001743309.1 identified by Glimmer3; putative YP_001743310.1 identified by match to protein family HMM PF00583 YP_001743311.1 yedK; identified by match to protein family HMM PF02586 YP_001743312.1 identified by match to protein family HMM PF01206 YP_001743313.1 identified by match to protein family HMM PF04143 YP_001743315.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001743316.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001743317.1 flagellin specific chaperone YP_001743318.1 involved in flagellin assembly YP_001743319.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes YP_001743320.1 identified by Glimmer3; putative YP_001743321.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001743322.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_001743323.1 identified by match to protein family HMM PF00497 YP_001743324.1 catalyzes the formation of pyruvate from D-cysteine YP_001743325.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001743326.1 identified by match to protein family HMM PF00005 YP_001743327.1 regulates genes involved in cell division YP_001743330.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001743331.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001743332.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_001743333.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292 YP_001743334.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837 YP_001743336.1 cytoplasmic iron storage protein YP_001743337.1 identified by Glimmer3; putative YP_001743339.1 identified by Glimmer3; putative YP_001743340.1 identified by similarity to GB:ABB65745.1 YP_001743341.1 identified by match to protein family HMM PF00210 YP_001743342.1 identified by Glimmer3; putative YP_001743343.1 identified by match to protein family HMM PF00532 YP_001743344.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001743345.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001743346.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_001743347.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400 YP_001743348.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001743349.1 identified by Glimmer3; putative YP_001743350.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001743351.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001743352.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001743353.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001743354.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001743355.1 identified by match to protein family HMM PF01584 YP_001743356.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001743357.1 mediates taxis toward dipeptides YP_001743358.1 methylates the MCP YP_001743359.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001743360.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001743361.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001743362.1 identified by similarity to GB:ABA77767.1 YP_001743364.1 identified by Glimmer3; putative YP_001743365.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001743366.1 membrane protein involved in the flagellar export apparatus YP_001743367.1 identified by match to protein family HMM PF06366 YP_001743368.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001743369.1 identified by match to protein family HMM PF06185 YP_001743370.1 identified by match to protein family HMM PF03932 YP_001743371.1 identified by match to protein family HMM PF03264 YP_001743372.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409 YP_001743373.1 identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452 YP_001743374.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740 YP_001743376.1 identified by match to protein family HMM PF01904 YP_001743377.1 identified by match to protein family HMM PF00857 YP_001743378.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001743379.1 converts dATP to dAMP and pyrophosphate YP_001743380.1 yebC; identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001743381.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001743382.1 identified by match to protein family HMM PF06520 YP_001743383.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001743384.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001743385.1 involved in transport of zinc(II) with ZnuA and C YP_001743386.1 involved in transport of zinc(II) with ZnuA and C YP_001743387.1 involved in transport of zinc(II) with ZnuA and C YP_001743388.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_001743389.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001743390.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001743391.1 Represses the expression of the zwf, eda, glp and gap YP_001743393.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001743394.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001743395.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001743396.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001743397.1 identified by match to protein family HMM PF07130 YP_001743398.1 secreted protein; unknown function YP_001743399.1 identified by match to protein family HMM PF04391 YP_001743400.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_001743401.1 3'-5' exonuclease activity on single or double-strand DNA YP_001743402.1 identified by match to protein family HMM PF00795 YP_001743403.1 identified by match to protein family HMM PF06440 YP_001743404.1 identified by match to protein family HMM PF04234 YP_001743405.1 identified by match to protein family HMM PF05425 YP_001743407.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_001743408.1 identified by match to protein family HMM PF07358 YP_001743409.1 identified by match to protein family HMM PF07351 YP_001743410.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001743411.1 identified by match to protein family HMM PF02470 YP_001743412.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_001743413.1 identified by match to protein family HMM PF01590 YP_001743414.1 affects solute and DNA transport through an unknown mechanism YP_001743415.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001743416.1 putative metalloprotease YP_001743417.1 identified by match to protein family HMM PF07690 YP_001743418.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001743423.1 identified by match to protein family HMM PF00313 YP_001743424.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001743425.1 membrane protein YebN YP_001743426.1 identified by match to protein family HMM PF06173 YP_001743427.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_001743428.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_001743429.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854 YP_001743430.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_001743431.1 identified by match to protein family HMM PF00563 YP_001743432.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001743433.1 identified by match to protein family HMM PF00293 YP_001743434.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553 YP_001743435.1 identified by match to protein family HMM PF03701 YP_001743436.1 identified by match to protein family HMM PF08986 YP_001743437.1 identified by match to protein family HMM PF01042 YP_001743439.1 identified by match to protein family HMM PF00814 YP_001743440.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_001743441.1 Activates fatty acids by binding to coenzyme A YP_001743442.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388 YP_001743443.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001743444.1 identified by match to protein family HMM PF00355 YP_001743445.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001743446.1 identified by match to protein family HMM PF00180; match to protein family HMM TIGR02089 YP_001743447.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743448.1 identified by match to protein family HMM PF01810 YP_001743449.1 identified by Glimmer3; putative YP_001743450.1 identified by match to protein family HMM PF09313 YP_001743451.1 identified by match to protein family HMM PF08956 YP_001743452.1 identified by Glimmer3; putative YP_001743453.1 identified by match to protein family HMM PF04226 YP_001743454.1 identified by Glimmer3; putative YP_001743455.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254 YP_001743456.1 identified by match to protein family HMM PF03891 YP_001743457.1 identified by match to protein family HMM PF04343 YP_001743458.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00896 YP_001743459.1 identified by match to protein family HMM PF00165 YP_001743460.1 identified by match to protein family HMM PF04284 YP_001743462.1 identified by match to protein family HMM PF04073 YP_001743463.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743464.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743465.1 identified by match to protein family HMM PF04285 YP_001743466.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_001743467.1 identified by match to protein family HMM PF06629 YP_001743468.1 identified by match to protein family HMM PF00248 YP_001743469.1 identified by match to protein family HMM PF01263 YP_001743470.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001743471.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001743472.1 identified by match to protein family HMM PF07023 YP_001743473.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001743474.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001743475.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001743476.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167 YP_001743477.1 identified by match to protein family HMM PF00294 YP_001743478.1 identified by match to protein family HMM PF00248 YP_001743479.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001743480.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001743481.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001743482.1 converts asparagine to aspartate and ammonia YP_001743483.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001743484.1 identified by match to protein family HMM PF00881 YP_001743485.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001743486.1 decatenates replicating daughter chromosomes YP_001743487.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001743488.1 identified by match to protein family HMM PF07383 YP_001743489.1 identified by match to protein family HMM PF00293 YP_001743490.1 identified by match to protein family HMM PF01066 YP_001743492.1 identified by match to protein family HMM PF00005 YP_001743495.1 identified by match to protein family HMM PF02627 YP_001743496.1 identified by match to protein family HMM PF09335 YP_001743498.1 identified by match to protein family HMM PF09335 YP_001743499.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001743500.1 identified by Glimmer3; putative YP_001743501.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_001743502.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03243; match to protein family HMM TIGR03244 YP_001743503.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001743504.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001743505.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001743506.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_001743507.1 identified by match to protein family HMM PF05962 YP_001743508.1 3' incision activity; acts with UvrC YP_001743509.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001743510.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001743511.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001743512.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001743513.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001743514.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_001743515.1 identified by match to protein family HMM PF02056 YP_001743516.1 identified by match to protein family HMM PF04794 YP_001743517.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_001743520.1 identified by match to protein family HMM PF00375 YP_001743521.1 identified by match to protein family HMM PF04307 YP_001743522.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001743524.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881 YP_001743526.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_001743527.1 ydiY; identified by similarity to SP:P76206; match to protein family HMM PF04338 YP_001743528.1 yniD; identified by similarity to SP:Q3Z269 YP_001743529.1 identified by similarity to SP:P76205; match to protein family HMM PF07906 YP_001743530.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001743531.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001743532.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_001743533.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001743534.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001743535.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001743536.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001743537.1 with BtuD and BtuF transports vitamin B12 into the cell YP_001743538.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_001743539.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_001743540.1 identified by match to protein family HMM PF00877 YP_001743542.1 identified by match to protein family HMM PF02696 YP_001743544.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001743545.1 identified by match to protein family HMM PF03618 YP_001743546.1 identified by Glimmer3; putative YP_001743547.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001743548.1 identified by similarity to SP:Q41364; match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_001743549.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001743550.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001743551.1 identified by match to protein family HMM PF00106 YP_001743552.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids YP_001743554.1 identified by similarity to SP:P68644; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_001743555.1 May play a role in a redox process YP_001743556.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001743557.1 identified by Glimmer3; putative YP_001743558.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883 YP_001743559.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001743560.1 ydiF; identified by similarity to GB:CAB77207.1; match to protein family HMM PF01144 YP_001743561.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_001743562.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_001743563.1 identified by match to protein family HMM PF07690 YP_001743564.1 identified by match to protein family HMM PF07690 YP_001743565.1 identified by match to protein family HMM PF08965 YP_001743566.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_001743567.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_001743568.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001743570.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_001743571.1 with SufCD activates cysteine desulfurase SufS YP_001743572.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001743573.1 with SufBC activates cysteine desulfurase SufS YP_001743574.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_001743575.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001743576.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_001743577.1 identified by match to protein family HMM PF04728 YP_001743578.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001743580.1 identified by Glimmer3; putative YP_001743581.1 identified by match to protein family HMM PF00037 YP_001743582.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730 YP_001743584.1 identified by match to protein family HMM PF00037 YP_001743585.1 identified by match to protein family HMM PF01292 YP_001743586.1 ydhT; identified by similarity to SP:P77147 YP_001743587.1 identified by match to protein family HMM PF08803 YP_001743589.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001743590.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001743591.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001743592.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001743593.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743594.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001743595.1 identified by Glimmer3; putative YP_001743596.1 identified by match to protein family HMM PF07690 YP_001743597.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_001743598.1 identified by match to protein family HMM PF00877 YP_001743599.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365 YP_001743600.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli YP_001743601.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001743602.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_001743603.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001743604.1 identified by match to protein family HMM PF00440 YP_001743605.1 identified by match to protein family HMM PF06945 YP_001743606.1 identified by match to protein family HMM PF00248 YP_001743607.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_001743608.1 identified by match to protein family HMM PF04632 YP_001743609.1 identified by match to protein family HMM PF00529 YP_001743610.1 identified by match to protein family HMM PF07869 YP_001743611.1 identified by Glimmer3; putative YP_001743612.1 Transcription regulator that can both activate or repress expression YP_001743613.1 identified by match to protein family HMM PF05433 YP_001743614.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001743615.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_001743616.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001743617.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001743618.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001743619.1 identified by similarity to SP:P0A9D2; match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001743620.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001743621.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_001743622.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001743623.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001743624.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001743625.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001743626.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001743627.1 identified by similarity to SP:P0A766; match to protein family HMM PF02508; match to protein family HMM TIGR01943 YP_001743629.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_001743630.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001743631.1 catalyzes the formation of inosine from adenosine YP_001743632.1 identified by similarity to SP:P23256; match to protein family HMM PF00155 YP_001743633.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_001743634.1 regulates malXY which are involved in maltose-glucose transport YP_001743635.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_001743636.1 identified by match to protein family HMM PF00440 YP_001743637.1 identified by match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837 YP_001743638.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_001743640.1 identified by match to protein family HMM PF06097 YP_001743641.1 identified by similarity to SP:P00946; match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_001743642.1 identified by similarity to SP:P0AC33; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001743643.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001743644.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001743645.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001743646.1 response regulator in two-component regulatory system with RstB YP_001743647.1 identified by match to protein family HMM PF06942 YP_001743648.1 identified by match to protein family HMM PF00106 YP_001743649.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_001743650.1 identified by match to protein family HMM PF07338 YP_001743651.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001743652.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001743653.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_001743654.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_001743655.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001743656.1 identified by match to protein family HMM PF00089 YP_001743657.1 required for growth and survival under moderately acid conditions YP_001743658.1 identified by match to protein family HMM PF01609 YP_001743659.1 identified by match to protein family HMM PF07690 YP_001743660.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743661.1 identified by match to protein family HMM PF00480 YP_001743662.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001743663.1 identified by match to protein family HMM PF00654 YP_001743664.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_001743665.1 identified by match to protein family HMM PF04976 YP_001743666.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_001743667.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001743668.1 identified by match to protein family HMM PF06649 YP_001743669.1 identified by match to protein family HMM PF06788 YP_001743670.1 identified by match to protein family HMM PF00583 YP_001743671.1 identified by match to protein family HMM PF06932 YP_001743672.1 identified by match to protein family HMM PF02694 YP_001743673.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001743674.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001743675.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001743676.1 identified by Glimmer3; putative YP_001743677.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001743678.1 identified by match to protein family HMM TIGR03318 YP_001743679.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001743680.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001743681.1 identified by match to protein family HMM PF01432 YP_001743682.1 ydeI; identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_001743683.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743684.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_001743685.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_001743686.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001743687.1 identified by match to protein family HMM PF02302 YP_001743688.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001743689.1 identified by match to protein family HMM PF02255 YP_001743690.1 identified by similarity to SP:P26218; match to protein family HMM PF02264 YP_001743691.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism YP_001743693.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF YP_001743694.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_001743695.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001743696.1 identified by match to protein family HMM PF07690 YP_001743697.1 identified by Glimmer3; putative YP_001743698.1 identified by Glimmer3; putative YP_001743700.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743701.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_001743702.1 catalyzes the formation of glutamate from glutamine YP_001743704.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743705.1 catalyzes the formation of D-tagaturonate from D-altronate YP_001743706.1 identified by match to protein family HMM PF05249 YP_001743707.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001743708.1 identified by match to protein family HMM PF03992 YP_001743709.1 identified by match to protein family HMM PF01791 YP_001743711.1 identified by match to protein family HMM PF02653 YP_001743712.1 identified by match to protein family HMM PF02653 YP_001743713.1 identified by match to protein family HMM PF00005 YP_001743714.1 identified by match to protein family HMM PF04198 YP_001743715.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001743716.1 ydeK; identified by match to protein family HMM PF03212; match to protein family HMM TIGR02601 YP_001743717.1 identified by Glimmer3; putative YP_001743718.1 identified by match to protein family HMM PF00419 YP_001743719.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001743720.1 identified by match to protein family HMM PF00577 YP_001743721.1 identified by match to protein family HMM PF00419 YP_001743722.1 ydeR; identified by similarity to SP:P08190; match to protein family HMM PF00419 YP_001743723.1 identified by match to protein family HMM PF00665 YP_001743724.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001743725.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160 YP_001743726.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family YP_001743727.1 identified by similarity to SP:Q7UCH6 YP_001743728.1 regulates the cellular response to acid resistance YP_001743729.1 identified by match to protein family HMM PF00884 YP_001743730.1 identified by match to protein family HMM PF04055 YP_001743731.1 identified by match to protein family HMM PF00005; match to protein family HMM PF05992; match to protein family HMM PF06472 YP_001743732.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_001743733.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001743734.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_001743735.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910 YP_001743736.1 identified by match to protein family HMM PF02638 YP_001743737.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743738.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate YP_001743739.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001743740.1 identified by match to protein family HMM PF00496 YP_001743741.1 identified by match to protein family HMM PF00528 YP_001743742.1 identified by match to protein family HMM PF00528 YP_001743743.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001743744.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001743745.1 identified by match to protein family HMM PF02566 YP_001743746.1 identified by Glimmer3; putative YP_001743748.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_001743749.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001743750.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001743751.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_001743752.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_001743753.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_001743754.1 Selenoprotein. identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553 YP_001743755.1 identified by match to protein family HMM PF00892 YP_001743756.1 identified by similarity to SP:P77747; match to protein family HMM PF00267 YP_001743757.1 identified by similarity to GB:ABB61785.1 YP_001743758.1 identified by similarity to RF:NP_837403.1 YP_001743759.1 identified by similarity to SP:P37758; match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_001743760.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_001743761.1 identified by similarity to SP:P19318; match to protein family HMM TIGR01660 YP_001743762.1 identified by similarity to SP:P19317; match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_001743763.1 identified by similarity to SP:P0AF32; match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_001743764.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_001743765.1 identified by match to protein family HMM PF00797 YP_001743766.1 identified by match to protein family HMM PF01613 YP_001743767.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_001743768.1 identified by match to protein family HMM PF00753 YP_001743769.1 identified by Glimmer3; putative YP_001743770.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001743771.1 identified by similarity to GB:ABB62052.1 YP_001743772.1 identified by match to protein family HMM PF00324 YP_001743774.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_001743775.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001743776.1 identified by Glimmer3; putative YP_001743777.1 identified by Glimmer3; putative YP_001743778.1 identified by match to protein family HMM PF00107 YP_001743779.1 identified by match to protein family HMM PF00583 YP_001743780.1 identified by match to protein family HMM PF04657 YP_001743783.1 identified by Glimmer3; putative YP_001743784.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001743785.1 identified by match to protein family HMM PF00528 YP_001743786.1 identified by match to protein family HMM PF00528 YP_001743787.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_001743788.1 identified by match to protein family HMM PF01547 YP_001743789.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_001743790.1 identified by match to protein family HMM PF01381; match to protein family HMM PF03681 YP_001743791.1 identified by Glimmer3; putative YP_001743793.1 identified by match to protein family HMM PF01136 YP_001743794.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_001743795.1 identified by match to protein family HMM PF03594; match to protein family HMM TIGR00843 YP_001743796.1 identified by match to protein family HMM PF01609 YP_001743797.1 identified by match to protein family HMM PF03594 YP_001743799.1 with TehA confers resistance to tellurite YP_001743800.1 identified by match to protein family HMM PF03595; match to protein family HMM TIGR00816 YP_001743802.1 identified by match to protein family HMM PF00583 YP_001743803.1 identified by match to protein family HMM PF04325 YP_001743804.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001743805.1 identified by match to protein family HMM PF07063 YP_001743806.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743807.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001743809.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_001743810.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001743811.1 NAD-linked YP_001743812.1 identified by match to protein family HMM PF02698 YP_001743813.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001743814.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001743815.1 identified by match to protein family HMM PF00782; match to protein family HMM PF01569 YP_001743817.1 identified by match to protein family HMM PF01148 YP_001743818.1 identified by match to protein family HMM PF01066 YP_001743820.1 identified by match to protein family HMM PF00248 YP_001743821.1 identified by match to protein family HMM PF03797 YP_001743822.1 identified by similarity to GB:CAD01687.1; match to protein family HMM PF07027 YP_001743825.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001743826.1 identified by match to protein family HMM PF03724 YP_001743828.1 identified by Glimmer3; putative YP_001743829.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176 YP_001743830.1 identified by similarity to SP:P77747; match to protein family HMM PF00267 YP_001743831.1 identified by match to protein family HMM PF00582 YP_001743832.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001743833.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001743834.1 identified by match to protein family HMM PF01544 YP_001743835.1 identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_001743836.1 identified by match to protein family HMM PF01713 YP_001743837.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743838.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_001743839.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891 YP_001743840.1 identified by match to protein family HMM PF03806; match to protein family HMM TIGR00819 YP_001743841.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_001743842.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001743843.1 with UspC and UspD is involved in resistance to UV irradiation YP_001743845.1 identified by match to protein family HMM PF00924 YP_001743846.1 identified by match to protein family HMM PF00496 YP_001743847.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001743848.1 identified by match to protein family HMM PF02129 YP_001743849.1 identified by match to protein family HMM PF05368 YP_001743850.1 identified by match to protein family HMM PF00246 YP_001743851.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001743852.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001743853.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001743854.1 ycjF; identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620 YP_001743855.1 identified by match to protein family HMM PF04317 YP_001743856.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001743857.1 identified by similarity to SP:P76045 YP_001743858.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_001743859.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009 YP_001743860.1 identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636 YP_001743861.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001743862.1 identified by match to protein family HMM PF01261 YP_001743863.1 identified by match to protein family HMM PF00107 YP_001743864.1 identified by match to protein family HMM PF00528 YP_001743865.1 identified by match to protein family HMM PF00528 YP_001743866.1 identified by match to protein family HMM PF01547 YP_001743867.1 identified by match to protein family HMM PF00128 YP_001743868.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_001743869.1 identified by match to protein family HMM TIGR02979 YP_001743870.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001743871.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001743872.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001743873.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001743874.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate YP_001743875.1 identified by match to protein family HMM PF01266 YP_001743876.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_001743877.1 regulates genes involved in putrescine degradation YP_001743878.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_001743879.1 identified by match to protein family HMM PF00120 YP_001743880.1 identified by match to protein family HMM PF00324 YP_001743882.1 identified by match to protein family HMM PF00496 YP_001743883.1 identified by match to protein family HMM PF00528 YP_001743884.1 identified by match to protein family HMM PF00528 YP_001743885.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001743886.1 identified by similarity to SP:P36638; match to protein family HMM PF00005 YP_001743887.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_001743888.1 identified by similarity to GB:CAD48863.1; match to protein family HMM PF02321; match to protein family HMM TIGR01845 YP_001743889.1 identified by similarity to GB:CAD48862.1; match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001743890.1 identified by similarity to GB:CAD48861.1; match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001743891.1 identified by match to protein family HMM PF00440 YP_001743892.1 identified by Glimmer3; putative YP_001743893.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001743895.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001743896.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_001743898.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001743900.1 involved in start site selection during the initiation of translation YP_001743901.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001743902.1 identified by Glimmer3; putative YP_001743903.1 identified by match to protein family HMM PF07719 YP_001743904.1 identified by match to protein family HMM PF06305 YP_001743905.1 identified by match to protein family HMM PF01569 YP_001743906.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001743907.1 Catalyzes the conversion of citrate to isocitrate YP_001743910.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001743911.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001743913.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001743914.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001743915.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001743916.1 identified by Glimmer3; putative YP_001743918.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001743920.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_001743921.1 identified by match to protein family HMM PF02811 YP_001743922.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001743923.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_001743924.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001743925.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001743926.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001743928.1 identified by match to protein family HMM PF05974 YP_001743929.1 identified by match to protein family HMM PF05974 YP_001743930.1 receptor for colicin S4 YP_001743931.1 identified by match to protein family HMM PF06790 YP_001743932.1 Involved in cell division; probably involved in intracellular septation YP_001743933.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_001743934.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001743935.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001743937.1 identified by match to protein family HMM PF00884 YP_001743938.1 ylcE; identified by Glimmer3; putative YP_001743939.1 identified by Glimmer3; putative YP_001743940.1 identified by similarity to GB:ABG71805.1 YP_001743941.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001743942.1 identified by match to protein family HMM PF00665 YP_001743943.1 identified by match to protein family HMM PF00665 YP_001743944.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885 YP_001743945.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001743946.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001743947.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001743948.1 identified by similarity to SP:P76027; match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001743949.1 identified by similarity to SP:P08006; match to protein family HMM PF00528 YP_001743950.1 identified by match to protein family HMM PF00528 YP_001743951.1 identified by match to protein family HMM PF00496 YP_001743952.1 identified by Glimmer3; putative YP_001743953.1 identified by Glimmer3; putative YP_001743954.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427 YP_001743955.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465 YP_001743956.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001743957.1 identified by Glimmer3; putative YP_001743958.1 identified by match to protein family HMM PF00816 YP_001743959.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001743960.1 identified by match to protein family HMM PF00072 YP_001743961.1 identified by match to protein family HMM PF01734 YP_001743962.1 identified by match to protein family HMM PF02810 YP_001743963.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001743964.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_001743965.1 identified by similarity to SP:P0AF26; match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_001743966.1 identified by similarity to SP:P11349; match to protein family HMM PF00037; match to protein family HMM TIGR01660 YP_001743967.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_001743968.1 identified by similarity to SP:P10903; match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_001743969.1 identified by Glimmer3; putative YP_001743970.1 identified by similarity to SP:P0AFA2; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001743971.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_001743972.1 ychO YP_001743973.1 identified by match to protein family HMM PF02635 YP_001743974.1 identified by match to protein family HMM PF04752 YP_001743975.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_001743976.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846 YP_001743979.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001743981.1 identified by match to protein family HMM PF04247 YP_001743982.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_001743983.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001743984.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001743985.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001743986.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001743987.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001743988.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001743989.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001743990.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001743991.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001743992.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_001743993.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001743994.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_001743995.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL YP_001743996.1 identified by Glimmer3; putative YP_001743998.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_001743999.1 identified by match to protein family HMM PF01497 YP_001744000.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032 YP_001744001.1 identified by match to protein family HMM PF00005 YP_001744002.1 identified by match to protein family HMM PF08242 YP_001744003.1 involved in molybdenum transport YP_001744004.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_001744005.1 identified by match to protein family HMM PF04226 YP_001744006.1 identified by match to protein family HMM PF07238; match to protein family HMM PF07317 YP_001744007.1 identified by match to protein family HMM PF01464 YP_001744008.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_001744009.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001744010.1 identified by similarity to GB:ABB61379.1 YP_001744011.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_001744012.1 catalyzes the oxidative deamination of D-amino acids YP_001744013.1 identified by match to protein family HMM PF04293 YP_001744014.1 Multifunctional regulator of fatty acid metabolism YP_001744015.1 involved in regulation of intracellular pH under alkaline conditions YP_001744016.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001744017.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001744018.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001744019.1 Acts by forming a pore-like structure upon contact with mammalian cells YP_001744020.1 identified by match to protein family HMM PF03692 YP_001744021.1 identified by match to protein family HMM PF01557 YP_001744022.1 identified by match to protein family HMM PF05166 YP_001744023.1 identified by match to protein family HMM PF04151 YP_001744024.1 identified by match to protein family HMM PF05666 YP_001744025.1 blocks the formation of polar Z-ring septums YP_001744026.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001744027.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001744028.1 identified by Glimmer3; putative YP_001744029.1 identified by Glimmer3; putative YP_001744031.1 identified by Glimmer3; putative YP_001744032.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001744033.1 identified by Glimmer3; putative YP_001744035.1 identified by match to protein family HMM PF00563 YP_001744038.1 identified by match to protein family HMM PF00563; match to protein family HMM PF04940 YP_001744039.1 identified by match to protein family HMM PF00376 YP_001744040.1 identified by match to protein family HMM PF07166 YP_001744041.1 Converts isocitrate to alpha ketoglutarate YP_001744042.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA YP_001744043.1 identified by match to protein family HMM PF00293 YP_001744044.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001744045.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001744046.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001744047.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001744048.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918 YP_001744049.1 identified by match to protein family HMM PF08007 YP_001744050.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001744051.1 identified by Glimmer3; putative YP_001744052.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_001744053.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_001744054.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_001744055.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_001744058.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001744059.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_001744060.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001744061.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_001744062.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001744063.1 identified by match to protein family HMM PF01757 YP_001744064.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_001744065.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_001744066.1 identified by match to protein family HMM PF07338 YP_001744067.1 identified by match to protein family HMM PF00440 YP_001744068.1 identified by match to protein family HMM PF05433 YP_001744069.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001744070.1 identified by match to protein family HMM PF05728 YP_001744071.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001744072.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_001744073.1 identified by match to protein family HMM TIGR02722 YP_001744074.1 identified by match to protein family HMM PF07233 YP_001744075.1 identified by match to protein family HMM PF01230 YP_001744077.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_001744078.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001744079.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_001744080.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001744081.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001744082.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_001744083.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001744084.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001744085.1 carries the fatty acid chain in fatty acid biosynthesis YP_001744086.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001744087.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_001744088.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001744089.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001744090.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001744091.1 identified by match to protein family HMM PF02620 YP_001744092.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001744093.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001744094.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001744095.1 identified by match to protein family HMM PF08681 YP_001744096.1 identified by match to protein family HMM PF00583 YP_001744097.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_001744098.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001744099.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001744100.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001744101.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001744102.1 makes up the distal portion of the flagellar basal body rod YP_001744103.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001744104.1 the hook connects flagellar basal body to the flagellar filament YP_001744105.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001744106.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001744107.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001744108.1 identified by Glimmer3; putative YP_001744109.1 required for the assembly of the flagellar basal body P-ring YP_001744110.1 regulates the flagellar specific sigma28 transcription factor YP_001744111.1 identified by match to protein family HMM PF05130 YP_001744112.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_001744113.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001744114.1 identified by match to protein family HMM PF04337 YP_001744115.1 identified by match to protein family HMM PF00583 YP_001744116.1 Confers resistance to norfloxacin and enoxacin YP_001744117.1 cofactor involved in the reduction of disulfides YP_001744118.1 identified by match to protein family HMM PF07273 YP_001744119.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001744120.1 identified by match to protein family HMM PF06183 YP_001744121.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001744122.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001744125.1 identified by match to protein family HMM PF01292 YP_001744126.1 identified by match to protein family HMM PF04264 YP_001744127.1 identified by match to protein family HMM PF00581 YP_001744128.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001744129.1 Confers resistance to fosfomycin and deoxycholate YP_001744131.1 identified by match to protein family HMM PF07119 YP_001744132.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001744133.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001744134.1 identified by Glimmer3; putative YP_001744135.1 identified by Glimmer3; putative YP_001744136.1 required for the transfer of succinyl residues to the glucan backbone YP_001744137.1 identified by match to protein family HMM PF00614 YP_001744138.1 identified by match to protein family HMM PF01661 YP_001744140.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_001744141.1 identified by match to protein family HMM PF07012 YP_001744142.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_001744143.1 identified by Glimmer3; putative YP_001744144.1 identified by Glimmer3; putative YP_001744145.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_001744146.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001744147.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001744148.1 identified by match to protein family HMM PF03783 YP_001744149.1 identified by match to protein family HMM PF06496 YP_001744150.1 identified by match to protein family HMM PF06192 YP_001744151.1 identified by match to protein family HMM PF02811 YP_001744152.1 identified by match to protein family HMM PF02826 YP_001744153.1 identified by similarity to GB:AAZ87768.1 YP_001744154.1 identified by match to protein family HMM PF02562 YP_001744155.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413 YP_001744156.1 identified by match to protein family HMM PF04302 YP_001744157.1 identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145 YP_001744158.1 identified by Glimmer3; putative YP_001744159.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_001744160.1 identified by Glimmer3; putative YP_001744162.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001744163.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08362 YP_001744164.1 identified by match to protein family HMM PF00296 YP_001744165.1 identified by match to protein family HMM PF00857 YP_001744166.1 identified by match to protein family HMM PF01042 YP_001744167.1 identified by match to protein family HMM PF00561 YP_001744168.1 identified by match to protein family HMM PF00881 YP_001744169.1 identified by match to protein family HMM PF01613 YP_001744170.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001744171.1 stationary phase protein that binds TrpR repressor YP_001744173.1 identified by match to protein family HMM PF00328 YP_001744175.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_001744176.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_001744177.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001744178.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164 YP_001744179.1 identified by match to protein family HMM PF03264; match to protein family HMM TIGR02162 YP_001744180.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001744181.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001744182.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_001744183.1 identified by match to protein family HMM PF00037 YP_001744184.1 identified by match to protein family HMM PF08178 YP_001744185.1 identified by Glimmer3; putative YP_001744186.1 identified by match to protein family HMM PF00313 YP_001744187.1 identified by match to protein family HMM PF00313 YP_001744188.1 identified by similarity to SP:P07102; match to protein family HMM PF00328 YP_001744189.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_001744190.1 identified by match to protein family HMM PF01654 YP_001744191.1 identified by match to protein family HMM PF04809 YP_001744192.1 involved in processing hydrogenase proteins HyaA and HyaB YP_001744193.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_001744194.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_001744195.1 involved in hydrogen cycling during fermentative growth YP_001744196.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_001744197.1 identified by Glimmer3; putative YP_001744198.1 identified by match to protein family HMM PF01027 YP_001744199.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_001744200.1 catalyzes the hydrolysis of acylphosphate YP_001744201.1 identified by match to protein family HMM PF03602 YP_001744202.1 identified by match to protein family HMM PF08755; match to protein family HMM TIGR02097 YP_001744203.1 identified by match to protein family HMM PF02629 YP_001744204.1 identified by Glimmer3; putative YP_001744206.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001744207.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001744208.1 identified by match to protein family HMM PF03733 YP_001744209.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667 YP_001744210.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994 YP_001744211.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623 YP_001744212.1 identified by Glimmer3; putative YP_001744213.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001744214.1 identified by match to protein family HMM PF06303 YP_001744216.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001744217.1 identified by match to protein family HMM PF03886 YP_001744218.1 identified by match to protein family HMM PF02470 YP_001744219.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_001744220.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001744221.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001744222.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476 YP_001744223.1 identified by match to protein family HMM PF07126 YP_001744224.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001744225.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001744226.1 identified by match to protein family HMM PF00419 YP_001744227.1 identified by match to protein family HMM PF00419 YP_001744228.1 identified by match to protein family HMM PF00419 YP_001744229.1 identified by match to protein family HMM PF00577 YP_001744230.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001744231.1 identified by match to protein family HMM PF00419 YP_001744232.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_001744233.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_001744234.1 catalyzes the release of sulfite from alkanesulfonates YP_001744235.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_001744236.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001744237.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 YP_001744239.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001744240.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001744241.1 outer membrane porin F; 1a; Ia; b YP_001744242.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001744243.1 identified by match to protein family HMM PF00753 YP_001744244.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409 YP_001744245.1 identified by match to protein family HMM PF01471 YP_001744246.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001744247.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001744248.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001744249.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001744250.1 identified by match to protein family HMM PF02698 YP_001744252.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001744253.1 identified by match to protein family HMM PF03966 YP_001744254.1 identified by match to protein family HMM PF06224 YP_001744255.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001744256.1 involved in the transport of lipid A across the inner membrane YP_001744257.1 ycaI; identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_001744258.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001744259.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001744260.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001744261.1 identified by match to protein family HMM PF01435 YP_001744262.1 identified by match to protein family HMM PF01609 YP_001744263.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001744264.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001744265.1 identified by match to protein family HMM PF04239 YP_001744266.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR00702 YP_001744267.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_001744268.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001744269.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001744270.1 identified by match to protein family HMM PF00324 YP_001744271.1 identified by match to protein family HMM PF07690 YP_001744272.1 identified by Glimmer3; putative YP_001744273.1 ycaC; identified by match to protein family HMM PF00857 YP_001744274.1 identified by match to protein family HMM PF04976 YP_001744275.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_001744276.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001744277.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001744278.1 identified by match to protein family HMM PF00004 YP_001744279.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001744280.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_001744281.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001744282.1 identified by Glimmer3; putative YP_001744283.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_001744284.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001744285.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001744286.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001744287.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001744289.1 identified by match to protein family HMM PF06117 YP_001744291.1 identified by match to protein family HMM PF06755 YP_001744292.1 identified by match to protein family HMM PF06154 YP_001744294.1 identified by match to protein family HMM PF06174 YP_001744295.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001744296.1 identified by match to protein family HMM PF03230 YP_001744297.1 identified by match to protein family HMM PF06067 YP_001744298.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001744299.1 identified by Glimmer3; putative YP_001744300.1 identified by match to protein family HMM PF01926 YP_001744301.1 identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497 YP_001744302.1 identified by match to protein family HMM PF03400 YP_001744304.1 identified by match to protein family HMM PF00534; match to protein family HMM PF00535 YP_001744305.1 identified by similarity to GB:ABM38486.1 YP_001744306.1 identified by match to protein family HMM PF01609 YP_001744307.1 identified by match to protein family HMM PF00665 YP_001744309.1 identified by match to protein family HMM PF01609 YP_001744310.1 identified by match to protein family HMM PF00535 YP_001744311.1 identified by match to protein family HMM PF00534 YP_001744312.1 identified by match to protein family HMM PF00535 YP_001744313.1 identified by match to protein family HMM PF03275; match to protein family HMM TIGR00031 YP_001744314.1 identified by match to protein family HMM PF01501 YP_001744315.1 identified by similarity to SP:Q48479; match to protein family HMM PF00005 YP_001744316.1 identified by similarity to SP:Q48475; match to protein family HMM PF01061 YP_001744317.1 identified by Glimmer3; putative YP_001744318.1 identified by Glimmer3; putative YP_001744319.1 identified by Glimmer3; putative YP_001744320.1 identified by match to protein family HMM PF01610 YP_001744321.1 identified by similarity to GB:AAL08430.1 YP_001744322.1 identified by similarity to GB:AAL08429.1 YP_001744323.1 identified by similarity to GB:AAL08427.1 YP_001744324.1 identified by match to protein family HMM PF00589 YP_001744325.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_001744326.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001744327.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible YP_001744328.1 with MacA is involved in the export of macrolide YP_001744329.1 confers macrolide resistance via active drug efflux YP_001744330.1 identified by match to protein family HMM PF04393 YP_001744332.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001744333.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001744334.1 identified by match to protein family HMM PF01207 YP_001744335.1 identified by match to protein family HMM PF03788 YP_001744336.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659 YP_001744337.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001744338.1 identified by match to protein family HMM PF02698 YP_001744340.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001744341.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001744342.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001744343.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001744344.1 identified by match to protein family HMM PF00532 YP_001744345.1 negative regulator of the mglBAC operon for galactose utilization YP_001744346.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_001744347.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001744348.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_001744349.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_001744350.1 identified by match to protein family HMM PF00324 YP_001744351.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001744352.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698 YP_001744353.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001744354.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08279 YP_001744355.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001744356.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively YP_001744357.1 activator of nucleoside metabolism YP_001744358.1 yeiM; identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001744359.1 identified by match to protein family HMM PF04227 YP_001744360.1 identified by match to protein family HMM PF00294 YP_001744361.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001744362.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001744363.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001744365.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001744366.1 identified by similarity to GB:CAH20558.1 YP_001744367.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_001744368.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001744369.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_001744370.1 identified by match to protein family HMM PF01569 YP_001744371.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001744372.1 identified by match to protein family HMM PF00563 YP_001744373.1 identified by match to protein family HMM PF00496 YP_001744374.1 identified by match to protein family HMM PF00528 YP_001744375.1 identified by match to protein family HMM PF00528 YP_001744376.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_001744378.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001744379.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001744380.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_001744381.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001744382.1 identified by match to protein family HMM PF04245 YP_001744383.1 identified by Glimmer3; putative YP_001744384.1 identified by match to protein family HMM PF07208 YP_001744385.1 identified by match to protein family HMM PF00884 YP_001744386.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_001744387.1 identified by match to protein family HMM PF03918 YP_001744388.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_001744389.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_001744390.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001744391.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_001744392.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_001744393.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_001744394.1 ATP-binding protein; required for proper cytochrome c maturation YP_001744395.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_001744396.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_001744397.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001744398.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001744399.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001744400.1 identified by match to protein family HMM PF03927 YP_001744401.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. YP_001744402.1 identified by Glimmer3; putative YP_001744403.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001744404.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001744405.1 efflux pump for the antibacterial peptide microcin J25 YP_001744406.1 identified by match to protein family HMM PF03171; match to protein family HMM TIGR00568 YP_001744407.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_001744408.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_001744409.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_001744410.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518 YP_001744411.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001744412.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001744413.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_001744414.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_001744415.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429 YP_001744416.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428 YP_001744417.1 identified by match to protein family HMM PF02667; match to protein family HMM TIGR00366 YP_001744418.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930 YP_001744421.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_001744422.1 identified by match to protein family HMM PF06672 YP_001744424.1 negatively supercoils closed circular double-stranded DNA YP_001744425.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001744426.1 identified by match to protein family HMM PF07690 YP_001744427.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001744428.1 Involved in ubiquinone biosynthesis YP_001744429.1 identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601 YP_001744430.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001744431.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001744432.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001744433.1 identified by match to protein family HMM PF06293 YP_001744434.1 identified by match to protein family HMM PF07690 YP_001744435.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001744436.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_001744437.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_001744438.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_001744439.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_001744440.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_001744441.1 identified by Glimmer3; putative YP_001744442.1 yfaD; identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001744444.1 identified by match to protein family HMM PF03328 YP_001744445.1 identified by match to protein family HMM PF07690 YP_001744446.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001744447.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001744448.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200 YP_001744449.1 identified by match to protein family HMM PF07437 YP_001744450.1 identified by match to protein family HMM PF00293 YP_001744451.1 identified by match to protein family HMM PF00300 YP_001744452.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001744453.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001744454.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001744455.1 identified by match to protein family HMM PF01522 YP_001744456.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001744457.1 identified by match to protein family HMM PF00893 YP_001744460.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923 YP_001744461.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001744462.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001744463.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_001744464.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001744465.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_001744466.1 identified by match to protein family HMM PF05957 YP_001744467.1 identified by match to protein family HMM PF00583 YP_001744468.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001744469.1 identified by Glimmer3; putative YP_001744470.1 identified by match to protein family HMM PF00092 YP_001744471.1 identified by Glimmer3; putative YP_001744472.1 yfbL; identified by match to protein family HMM PF04389 YP_001744473.1 identified by match to protein family HMM PF08974 YP_001744474.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744475.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744476.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001744477.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744478.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744479.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744480.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744481.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744482.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001744483.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744484.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001744485.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001744486.1 Catalyzes the transfer of electrons from NADH to quinone YP_001744487.1 identified by Glimmer3; putative YP_001744488.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001744489.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001744490.1 identified by match to protein family HMM PF01966 YP_001744491.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_001744492.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_001744493.1 identified by match to protein family HMM PF03887 YP_001744494.1 identified by match to protein family HMM PF04217 YP_001744496.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001744497.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001744498.1 identified by match to protein family HMM PF03606 YP_001744499.1 identified by match to protein family HMM PF00293 YP_001744500.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_001744501.1 identified by match to protein family HMM PF02798 YP_001744502.1 yfcG; identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001744503.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001744504.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_001744505.1 yfcI; identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001744506.1 identified by match to protein family HMM PF00005 YP_001744507.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001744508.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001744509.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001744510.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001744511.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001744512.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001744513.1 membrane protein required for colicin V production YP_001744514.1 identified by match to protein family HMM PF05036 YP_001744515.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_001744516.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001744517.1 identified by match to protein family HMM PF09335 YP_001744518.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001744519.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774 YP_001744520.1 identified by Glimmer3; putative YP_001744521.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001744522.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001744523.1 identified by match to protein family HMM PF07690 YP_001744524.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001744525.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001744526.1 identified by match to protein family HMM PF08891 YP_001744527.1 identified by match to protein family HMM PF04315 YP_001744528.1 identified by match to protein family HMM PF01925 YP_001744529.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001744530.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001744531.1 involved in methylation of ribosomal protein L3 YP_001744532.1 identified by match to protein family HMM PF01713 YP_001744535.1 yfcO; identified by similarity to GB:AAN81328.1 YP_001744536.1 yfcP; identified by match to protein family HMM PF00419 YP_001744537.1 yfcQ YP_001744538.1 yfcR; identified by similarity to GB:AAV76235.1 YP_001744539.1 yfcS; identified by match to protein family HMM PF00345 YP_001744540.1 yfcU; identified by match to protein family HMM PF00577 YP_001744541.1 yfcV; identified by similarity to GB:AAC64152.1; match to protein family HMM PF00419 YP_001744542.1 identified by similarity to SP:P76502; match to protein family HMM PF00300; match to protein family HMM TIGR00249 YP_001744543.1 identified by Glimmer3; putative YP_001744544.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001744545.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001744546.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_001744547.1 identified by match to protein family HMM PF03349 YP_001744548.1 identified by similarity to GB:AAP17747.1 YP_001744549.1 identified by match to protein family HMM PF04333 YP_001744552.1 identified by match to protein family HMM PF03938 YP_001744553.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601 YP_001744554.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281 YP_001744555.1 identified by similarity to SP:P0ADH5; match to protein family HMM PF00589 YP_001744556.1 identified by similarity to SP:P0ADH5; match to protein family HMM PF00589 YP_001744557.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001744558.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001744559.1 catalyzes the formation of pyruvate from serine YP_001744560.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001744561.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_001744562.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_001744563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518 YP_001744564.1 identified by match to protein family HMM PF02515 YP_001744565.1 member of the AEC family of auxin efflux transporters; unknown function YP_001744566.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_001744567.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA YP_001744569.1 identified by Glimmer3; putative YP_001744572.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001744573.1 identified by Glimmer3; putative YP_001744574.1 identified by match to protein family HMM PF00155 YP_001744575.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_001744576.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_001744577.1 identified by match to protein family HMM PF00165 YP_001744578.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417 YP_001744579.1 metalloprotein YP_001744580.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase YP_001744581.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_001744582.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829 YP_001744583.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001744584.1 identified by match to protein family HMM PF00654 YP_001744586.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_001744587.1 identified by similarity to SP:P0AFF2; match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001744588.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF05231 YP_001744590.1 identified by match to protein family HMM PF07037 YP_001744591.1 identified by Glimmer3; putative YP_001744592.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001744593.1 identified by Glimmer3; putative YP_001744594.1 identified by similarity to SP:P23841; match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001744595.1 identified by similarity to GB:AAX66324.1; match to protein family HMM TIGR03510 YP_001744596.1 identified by similarity to SP:P45562; match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001744597.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001744598.1 yfeN; identified by match to protein family HMM PF07135 YP_001744599.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001744602.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001744603.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001744604.1 putative role in sulfur assimilation YP_001744605.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001744606.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001744607.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001744608.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001744609.1 identified by match to protein family HMM PF01609 YP_001744610.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001744612.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001744613.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968 YP_001744614.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001744615.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139 YP_001744616.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_001744617.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_001744618.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001744619.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001744620.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_001744621.1 identified by match to protein family HMM PF00144 YP_001744622.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413 YP_001744623.1 identified by match to protein family HMM PF06572 YP_001744625.1 identified by match to protein family HMM PF00583 YP_001744626.1 identified by similarity to SP:P36548; match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_001744627.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001744628.1 activates the transcription of the ethanolamine utilization operon YP_001744629.1 identified by match to protein family HMM PF00936 YP_001744630.1 identified by match to protein family HMM PF00936 YP_001744631.1 catalyzes the formation of acetaldehyde from ethanolamine YP_001744632.1 identified by match to protein family HMM PF06751 YP_001744633.1 ethanolamine utilization protein EutA YP_001744634.1 identified by match to protein family HMM PF04346 YP_001744635.1 identified by match to protein family HMM PF00465 YP_001744636.1 identified by match to protein family HMM TIGR02529 YP_001744637.1 identified by match to protein family HMM PF00171 YP_001744638.1 identified by match to protein family HMM PF03319 YP_001744639.1 identified by match to protein family HMM PF00936 YP_001744640.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_001744641.1 identified by match to protein family HMM PF01923 YP_001744642.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249 YP_001744643.1 identified by match to protein family HMM TIGR02528 YP_001744644.1 identified by match to protein family HMM PF00936 YP_001744645.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001744646.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_001744647.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001744648.1 identified by match to protein family HMM PF06674 YP_001744649.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052 YP_001744650.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001744651.1 identified by similarity to SP:P27896; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001744652.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001744653.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_001744654.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001744656.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001744657.1 identified by match to protein family HMM PF05127 YP_001744658.1 identified by match to protein family HMM PF04228 YP_001744659.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001744660.1 identified by match to protein family HMM PF06804 YP_001744661.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001744662.1 negative transcriptional regulator of the gcvTHP operon YP_001744663.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001744664.1 identified by match to protein family HMM PF00037 YP_001744665.1 identified by similarity to SP:P23482; match to protein family HMM PF00361 YP_001744666.1 identified by match to protein family HMM PF00146 YP_001744667.1 identified by similarity to SP:P77416; match to protein family HMM PF00361 YP_001744668.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_001744669.1 identified by match to protein family HMM PF00361 YP_001744670.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346 YP_001744671.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_001744672.1 identified by match to protein family HMM PF01058 YP_001744673.1 identified by match to protein family HMM PF07450 YP_001744674.1 identified by similarity to SP:P71229; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954 YP_001744675.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon YP_001744676.1 identified by match to protein family HMM PF01594 YP_001744677.1 identified by match to protein family HMM PF01435 YP_001744678.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_001744679.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001744680.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001744681.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001744682.1 identified by Glimmer3; putative YP_001744683.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001744684.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001744685.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001744686.1 identified by match to protein family HMM PF02541 YP_001744687.1 yfgF; identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_001744690.1 identified by match to protein family HMM PF05433 YP_001744692.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001744693.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001744694.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001744695.1 identified by match to protein family HMM PF05688; match to protein family HMM PF05689 YP_001744698.1 identified by similarity to GB:AAP83330.1; match to protein family HMM PF07191 YP_001744699.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001744700.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001744702.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001744703.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001744704.1 identified by match to protein family HMM PF01381 YP_001744705.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001744706.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001744707.1 penicillin-insensitive transglycosylase/transpeptidase YP_001744708.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_001744709.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_001744710.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001744711.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001744712.1 identified by match to protein family HMM PF04384; match to protein family HMM TIGR03412 YP_001744713.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 YP_001744714.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001744715.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001744716.1 identified by Glimmer3; putative YP_001744717.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_001744718.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999 YP_001744719.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001744720.1 regulates the expression of the iscRSUA operon YP_001744721.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050 YP_001744722.1 identified by match to protein family HMM PF00459 YP_001744724.1 identified by match to protein family HMM PF00874 YP_001744725.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_001744726.1 activator of 3-phenylpropionic acid catabolism YP_001744727.1 identified by match to protein family HMM PF00355; match to protein family HMM PF00848 YP_001744728.1 identified by match to protein family HMM PF00866 YP_001744729.1 identified by match to protein family HMM PF00355 YP_001744730.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_001744731.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_001744732.1 identified by match to protein family HMM PF07681 YP_001744733.1 identified by match to protein family HMM PF01263 YP_001744734.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001744735.1 identified by match to protein family HMM PF02653 YP_001744736.1 identified by match to protein family HMM PF00005 YP_001744737.1 identified by match to protein family HMM PF00532 YP_001744738.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001744739.1 identified by match to protein family HMM PF00480 YP_001744740.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001744741.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001744742.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001744743.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728 YP_001744745.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001744746.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001744747.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001744748.1 identified by match to protein family HMM PF00383 YP_001744749.1 identified by match to protein family HMM TIGR01545 YP_001744750.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001744752.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001744753.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001744754.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001744755.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001744756.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001744757.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001744758.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001744759.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001744760.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001744761.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873 YP_001744762.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001744763.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001744764.1 identified by match to protein family HMM PF05175 YP_001744765.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001744766.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001744767.1 identified by match to protein family HMM PF01810 YP_001744768.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001744769.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001744770.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_001744771.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001744772.1 identified by match to protein family HMM PF03942 YP_001744773.1 identified by match to protein family HMM PF00583; match to protein family HMM PF02629 YP_001744774.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001744776.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001744777.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_001744778.1 yfiH; identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_001744779.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001744780.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001744781.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_001744782.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001744783.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001744784.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001744787.1 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001744788.1 identified by match to protein family HMM PF00691 YP_001744789.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001744790.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001744791.1 Essential for efficient processing of 16S rRNA YP_001744792.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001744793.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001744794.1 identified by match to protein family HMM PF01578 YP_001744795.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001744797.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001744798.1 catalyzes the phosphorylation of NAD to NADP YP_001744799.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_001744800.1 identified by match to protein family HMM PF04355 YP_001744801.1 identified by match to protein family HMM PF03658 YP_001744802.1 identified by match to protein family HMM PF03364 YP_001744803.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001744804.1 identified by Glimmer3; putative YP_001744805.1 identified by Glimmer3; putative YP_001744806.1 identified by Glimmer3; putative YP_001744807.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02806 YP_001744808.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_001744809.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001744810.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_001744811.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001744812.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773 YP_001744813.1 regulator of gab gene expression YP_001744814.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972 YP_001744815.1 identified by match to protein family HMM PF01679 YP_001744816.1 identified by match to protein family HMM PF01022 YP_001744818.1 identified by match to protein family HMM PF00816 YP_001744819.1 identified by match to protein family HMM PF06610 YP_001744821.1 identified by match to protein family HMM PF05957 YP_001744822.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_001744823.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_001744824.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_001744825.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001744826.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001744827.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001744828.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_001744829.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001744830.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001744831.1 identified by Glimmer3; putative YP_001744832.1 identified by match to protein family HMM PF07690 YP_001744833.1 identified by match to protein family HMM PF03591 YP_001744835.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001744836.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_001744837.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001744838.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001744839.1 involved in the first step of glutathione biosynthesis YP_001744841.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001744842.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001744843.1 identified by Glimmer3; putative YP_001744844.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001744845.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001744846.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001744847.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_001744848.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001744849.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821 YP_001744850.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825 YP_001744851.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001744852.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_001744853.1 regulator for glucitol utilization YP_001744854.1 regulates genes involved in glucitol utilization YP_001744855.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_001744856.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001744857.1 detoxifies nitric oxide using NADH YP_001744858.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001744859.1 identified by similarity to SP:P30131; match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_001744860.1 involved in electron transport from formate to hydrogen YP_001744861.1 identified by Glimmer3; putative YP_001744862.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001744863.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001744864.1 identified by match to protein family HMM PF00232 YP_001744865.1 identified by similarity to GB:AAN81725.1 YP_001744866.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_001744867.1 identified by match to protein family HMM PF07450 YP_001744868.1 identified by match to protein family HMM PF01058 YP_001744869.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_001744870.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346 YP_001744871.1 identified by match to protein family HMM PF00146 YP_001744872.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_001744873.1 identified by match to protein family HMM PF00037 YP_001744874.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_001744875.1 plays a role in hydrogenase nickel cofactor insertion YP_001744876.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_001744877.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_001744878.1 identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_001744879.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_001744880.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_001744881.1 identified by match to protein family HMM PF03459; match to protein family HMM TIGR00638 YP_001744882.1 ygbA YP_001744883.1 identified by Glimmer3; putative YP_001744884.1 This protein performs the mismatch recognition step during the DNA repair process YP_001744885.1 identified by similarity to SP:P55799; match to protein family HMM PF00149 YP_001744887.1 identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148 YP_001744888.1 identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421 YP_001744889.1 identified by match to protein family HMM PF01047 YP_001744890.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001744891.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001744892.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001744893.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001744894.1 catalyzes the modification of U13 in tRNA(Glu) YP_001744895.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001744896.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001744897.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001744898.1 identified by Glimmer3; putative YP_001744900.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001744901.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001744902.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001744903.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_001744905.1 identified by Glimmer3; putative YP_001744906.1 identified by match to protein family HMM TIGR01873 YP_001744907.1 identified by match to protein family HMM TIGR00287 YP_001744908.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907 YP_001744909.1 identified by match to protein family HMM TIGR01868; match to protein family HMM TIGR02593 YP_001744910.1 identified by match to protein family HMM TIGR01869 YP_001744911.1 identified by match to protein family HMM TIGR02548 YP_001744912.1 identified by match to protein family HMM TIGR02547 YP_001744913.1 identified by match to protein family HMM TIGR01587 YP_001744914.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001744915.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001744916.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001744917.1 identified by Glimmer3; putative YP_001744918.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367 YP_001744919.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_001744920.1 identified by match to protein family HMM PF00037 YP_001744921.1 identified by match to protein family HMM PF04309 YP_001744922.1 identified by match to protein family HMM PF00766 YP_001744923.1 identified by match to protein family HMM PF01012 YP_001744924.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001744925.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_001744926.1 identified by match to protein family HMM PF00106 YP_001744927.1 identified by match to protein family HMM PF07690 YP_001744928.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001744929.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_001744930.1 identified by similarity to SP:P22340; match to protein family HMM PF02264 YP_001744931.1 identified by similarity to SP:P08470; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR01996 YP_001744932.1 identified by similarity to SP:P37075; match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_001744933.1 identified by similarity to SP:P37076; match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR02417 YP_001744935.1 identified by Glimmer3; putative YP_001744936.1 identified by match to protein family HMM PF04011 YP_001744937.1 identified by similarity to GB:ABF04769.1; match to protein family HMM PF04536 YP_001744938.1 identified by match to protein family HMM PF04536 YP_001744939.1 identified by match to protein family HMM PF04536 YP_001744940.1 identified by match to protein family HMM PF01609 YP_001744941.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001744942.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001744943.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001744944.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system YP_001744945.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF YP_001744946.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001744947.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001744948.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001744949.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247 YP_001744950.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001744951.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001744952.1 identified by Glimmer3; putative YP_001744953.1 identified by Glimmer3; putative YP_001744954.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001744955.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001744956.1 identified by match to protein family HMM PF04287 YP_001744957.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001744958.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001744959.1 identified by match to protein family HMM PF03641 YP_001744960.1 identified by match to protein family HMM TIGR00814 YP_001744961.1 identified by similarity to SP:P30744; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001744962.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001744963.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_001744964.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001744965.1 identified by Glimmer3; putative YP_001744966.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_001744967.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_001744968.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628 YP_001744969.1 identified by match to protein family HMM PF05025 YP_001744970.1 regulates expression of genes involved in L-fucose utilization YP_001744972.1 identified by match to protein family HMM PF04241 YP_001744973.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001744974.1 identified by match to protein family HMM PF06004 YP_001744975.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392 YP_001744976.1 identified by match to protein family HMM PF02657; match to protein family HMM TIGR03391 YP_001744977.1 identified by match to protein family HMM PF00899 YP_001744978.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001744979.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001744980.1 identified by match to protein family HMM PF01380 YP_001744981.1 identified by match to protein family HMM PF00155 YP_001744982.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826 YP_001744983.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_001744984.1 identified by Glimmer3; putative YP_001744985.1 identified by similarity to SP:P63883; match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_001744986.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001744987.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001744988.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001744989.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001744990.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001744991.1 identified by match to protein family HMM TIGR02532 YP_001744993.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001744994.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001744995.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001744996.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001744997.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001744998.1 hydrolyzes diadenosine polyphosphate YP_001744999.1 identified by Glimmer3; putative YP_001745000.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001745001.1 identified by match to protein family HMM PF03741 YP_001745002.1 identified by match to protein family HMM PF06004 YP_001745003.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001745004.1 identified by match to protein family HMM PF07690 YP_001745005.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001745006.1 controls transcription of galETKM YP_001745007.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001745008.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001745009.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_001745010.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_001745011.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_001745012.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001745013.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001745014.1 identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814 YP_001745017.1 identified by match to protein family HMM PF03400 YP_001745018.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_001745019.1 putative molybdenum cofactor-binding protein; participates in purine salvage YP_001745020.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage YP_001745021.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage YP_001745022.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954 YP_001745023.1 identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316 YP_001745024.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001745025.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_001745026.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001745027.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001745028.1 identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309 YP_001745029.1 identified by match to protein family HMM TIGR03172 YP_001745030.1 identified by match to protein family HMM TIGR03310 YP_001745031.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_001745032.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_001745033.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_001745034.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_001745035.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001745036.1 Catalyzes the deamination of guanine YP_001745037.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001745038.1 identified by match to protein family HMM PF00037 YP_001745039.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001745040.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001745041.1 identified by Glimmer3; putative YP_001745042.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_001745043.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001745044.1 programmed frameshift; recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001745045.1 5'-3' single-stranded-DNA-specific exonuclease YP_001745046.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001745047.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001745048.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001745049.1 identified by match to protein family HMM PF07254 YP_001745050.1 identified by match to protein family HMM PF03937 YP_001745051.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001745052.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_001745053.1 identified by match to protein family HMM PF06164 YP_001745054.1 identified by match to protein family HMM PF00232 YP_001745055.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001745056.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001745057.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001745059.1 identified by Glimmer3; putative YP_001745060.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988 YP_001745061.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001745062.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001745063.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001745064.1 identified by match to protein family HMM PF05164 YP_001745065.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_001745066.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001745067.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001745068.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001745069.1 identified by similarity to SP:Q9L867; match to protein family HMM PF02525 YP_001745070.1 identified by match to protein family HMM PF07338 YP_001745071.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF01794; match to protein family HMM PF08022 YP_001745072.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001745073.1 MDM; functions in conversion of succinate to propionate YP_001745074.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001745075.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_001745076.1 identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458 YP_001745077.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001745078.1 identified by match to protein family HMM PF04402 YP_001745079.1 Involved in the export of arginine YP_001745080.1 identified by match to protein family HMM PF03480 YP_001745081.1 participates in the regulation of osmotic pressure changes within the cel YP_001745082.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001745083.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001745084.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001745085.1 identified by match to protein family HMM PF03479 YP_001745088.1 identified by match to protein family HMM PF00005 YP_001745089.1 identified by match to protein family HMM PF00005 YP_001745091.1 identified by match to protein family HMM PF05068 YP_001745092.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330 YP_001745093.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001745094.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein YP_001745095.1 identified by match to protein family HMM PF01145 YP_001745096.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001745097.1 identified by match to protein family HMM PF01435 YP_001745098.1 catalyzes the formation of putrescine from agmatine YP_001745100.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001745102.1 identified by similarity to RF:NP_838428.1 YP_001745103.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001745104.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_001745105.1 identified by match to protein family HMM PF03926 YP_001745106.1 identified by match to protein family HMM PF04231 YP_001745107.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001745108.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001745109.1 identified by match to protein family HMM PF02622 YP_001745110.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001745111.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420 YP_001745112.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_001745113.1 identified by match to protein family HMM PF02325 YP_001745114.1 yggU; identified by similarity to SP:Q83JS1; match to protein family HMM PF02594; match to protein family HMM TIGR00251 YP_001745115.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001745116.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001745117.1 identified by match to protein family HMM PF06717 YP_001745118.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001745121.1 identified by match to protein family HMM PF04320 YP_001745122.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001745123.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_001745124.1 identified by match to protein family HMM PF04362 YP_001745125.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001745126.1 identified by Glimmer3; putative YP_001745127.1 identified by similarity to SP:P0AFF5; match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001745128.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001745129.1 identified by match to protein family HMM PF00589 YP_001745130.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001745131.1 identified by match to protein family HMM PF02065 YP_001745132.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001745133.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_001745134.1 identified by similarity to GB:AAB71432.1 YP_001745135.1 identified by similarity to SP:P19777 YP_001745136.1 identified by match to protein family HMM PF03811 YP_001745138.1 identified by match to protein family HMM PF01527 YP_001745139.1 identified by Glimmer3; putative YP_001745140.1 identified by match to protein family HMM PF03050 YP_001745141.1 identified by Glimmer3; putative YP_001745142.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor YP_001745143.1 identified by Glimmer3; putative YP_001745144.1 identified by Glimmer3; putative YP_001745145.1 identified by similarity to SP:P16943 YP_001745146.1 identified by Glimmer3; putative YP_001745147.1 identified by match to protein family HMM PF05717 YP_001745148.1 identified by match to protein family HMM PF01527 YP_001745149.1 identified by similarity to SP:P63883; match to protein family HMM PF01520 YP_001745150.1 identified by Glimmer3; putative YP_001745151.1 identified by match to protein family HMM PF01695 YP_001745152.1 identified by match to protein family HMM PF00665 YP_001745153.1 identified by similarity to GB:AAM53134.1; match to protein family HMM PF02195 YP_001745154.1 identified by similarity to GB:AAM53133.1; match to protein family HMM PF01507 YP_001745155.1 identified by Glimmer3; putative YP_001745156.1 identified by match to protein family HMM PF01527 YP_001745157.1 identified by Glimmer3; putative YP_001745158.1 identified by Glimmer3; putative YP_001745159.1 identified by similarity to SP:P53636; match to protein family HMM PF00080 YP_001745160.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001745161.1 identified by match to protein family HMM PF00665 YP_001745162.1 identified by Glimmer3; putative YP_001745163.1 identified by Glimmer3; putative YP_001745164.1 identified by similarity to GB:AAT11264.1; match to protein family HMM PF01297 YP_001745165.1 identified by similarity to GB:AAT11265.1; match to protein family HMM PF00005 YP_001745166.1 identified by similarity to GB:AAT11266.1; match to protein family HMM PF00950; match to protein family HMM PF01032 YP_001745167.1 identified by similarity to GB:AAT11267.1; match to protein family HMM PF00950 YP_001745168.1 identified by similarity to SP:P14542; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_001745169.1 identified by similarity to SP:P11295 YP_001745170.1 identified by similarity to SP:Q47318; match to protein family HMM PF04183 YP_001745171.1 identified by similarity to SP:Q47317 YP_001745172.1 identified by similarity to SP:Q47316; match to protein family HMM PF04183 YP_001745173.1 identified by match to protein family HMM PF07690 YP_001745174.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05662; match to protein family HMM TIGR01409 YP_001745175.1 identified by Glimmer3; putative YP_001745176.1 identified by Glimmer3; putative YP_001745177.1 identified by Glimmer3; putative YP_001745178.1 identified by Glimmer3; putative YP_001745179.1 identified by match to protein family HMM PF05930 YP_001745180.1 identified by Glimmer3; putative YP_001745182.1 identified by Glimmer3; putative YP_001745183.1 identified by Glimmer3; putative YP_001745184.1 identified by Glimmer3; putative YP_001745185.1 identified by match to protein family HMM PF01926 YP_001745186.1 identified by Glimmer3; putative YP_001745187.1 identified by match to protein family HMM PF08279 YP_001745188.1 identified by Glimmer3; putative YP_001745189.1 identified by match to protein family HMM PF06006 YP_001745190.1 identified by match to protein family HMM PF06067 YP_001745191.1 identified by match to protein family HMM PF03230 YP_001745192.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001745193.1 identified by match to protein family HMM PF06174 YP_001745194.1 identified by similarity to SP:P76364; match to protein family HMM PF06154 YP_001745195.1 identified by match to protein family HMM PF06755 YP_001745197.1 identified by match to protein family HMM PF06117 YP_001745199.1 identified by match to protein family HMM PF03693; match to protein family HMM TIGR02606 YP_001745200.1 identified by Glimmer3; putative YP_001745201.1 identified by Glimmer3; putative YP_001745202.1 identified by similarity to SP:Q47334; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_001745203.1 identified by similarity to SP:P42501; match to protein family HMM TIGR01010 YP_001745204.1 identified by similarity to SP:Q03961; match to protein family HMM PF02563 YP_001745205.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001745206.1 identified by similarity to SP:P42217; match to protein family HMM PF05159 YP_001745207.1 identified by similarity to SP:P42218; match to protein family HMM PF05159 YP_001745208.1 identified by similarity to GB:AAA24213.1; match to protein family HMM PF07388 YP_001745209.1 identified by similarity to GB:AAY17379.1 YP_001745210.1 identified by similarity to SP:Q47400; match to protein family HMM PF02350 YP_001745211.1 identified by similarity to SP:P13266; match to protein family HMM PF02348 YP_001745212.1 identified by similarity to GB:AAC43302.1; match to protein family HMM PF03102; match to protein family HMM PF08666 YP_001745213.1 identified by similarity to GB:AAC43301.1 YP_001745214.1 identified by similarity to SP:P23888; match to protein family HMM PF00005 YP_001745215.1 identified by similarity to SP:P23889; match to protein family HMM PF01061 YP_001745216.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001745217.1 identified by match to protein family HMM PF01797 YP_001745218.1 identified by similarity to SP:Q46832; match to protein family HMM PF04612 YP_001745219.1 similar to general secretory pathway protein L YP_001745220.1 identified by similarity to GB:AAL10700.1; match to protein family HMM PF03934 YP_001745221.1 identified by similarity to GB:AAL60190.1; match to protein family HMM TIGR01711 YP_001745222.1 identified by similarity to GB:AAL60189.1; match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532 YP_001745223.1 identified by similarity to GB:AAL60188.1; match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001745224.1 identified by similarity to GB:AAL60187.1; match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532 YP_001745225.1 identified by similarity to GB:AAL60186.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120 YP_001745226.1 identified by similarity to GB:AAL60185.1; match to protein family HMM PF00437; match to protein family HMM TIGR02533 YP_001745227.1 identified by similarity to GB:AAL60184.1; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517 YP_001745228.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm YP_001745230.1 identified by similarity to GB:AAL60181.1; match to protein family HMM PF01478; match to protein family HMM PF06750 YP_001745232.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_001745233.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001745234.1 identified by match to protein family HMM PF03928 YP_001745235.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02754 YP_001745236.1 identified by match to protein family HMM PF01565 YP_001745237.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387 YP_001745238.1 identified by similarity to SP:P0ACL5; match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001745239.1 identified by Glimmer3; putative YP_001745240.1 activates fatty acids by binding to coenzyme A YP_001745241.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; match to protein family HMM PF07993 YP_001745242.1 identified by match to protein family HMM PF00550 YP_001745243.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00202 YP_001745244.1 identified by match to protein family HMM PF03739 YP_001745245.1 identified by match to protein family HMM PF03739 YP_001745246.1 ytfJ; identified by match to protein family HMM TIGR01626 YP_001745247.1 identified by similarity to GB:AAP18318.1 YP_001745248.1 identified by match to protein family HMM PF01943 YP_001745252.1 identified by match to protein family HMM PF01384 YP_001745253.1 identified by Glimmer3; putative YP_001745254.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_001745255.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001745256.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_001745257.1 plays a role in hydrogenase nickel cofactor insertion YP_001745259.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_001745260.1 involved in hydrogen uptake YP_001745261.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_001745262.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_001745263.1 involved in hydrogen uptake YP_001745264.1 identified by Glimmer3; putative YP_001745266.1 yghX; identified by match to protein family HMM PF01738; match to protein family HMM PF08840 YP_001745267.1 identified by match to protein family HMM PF00248 YP_001745268.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645 YP_001745269.1 identified by match to protein family HMM PF00106 YP_001745270.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001745271.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001745272.1 catalyzes the formation of L-homocysteine from cystathionine YP_001745273.1 identified by match to protein family HMM PF09335 YP_001745274.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06719 YP_001745275.1 identified by Glimmer3; putative YP_001745276.1 identified by match to protein family HMM PF00465 YP_001745277.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001745278.1 identified by Glimmer3; putative YP_001745280.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497 YP_001745281.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001745282.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001745283.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001745284.1 identified by match to protein family HMM PF02615 YP_001745285.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001745286.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001745287.1 identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409 YP_001745288.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_001745289.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001745290.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system YP_001745291.1 identified by match to protein family HMM PF06445 YP_001745292.1 ygiW; identified by similarity to SP:P0ADU5; match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_001745293.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_001745294.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001745295.1 identified by match to protein family HMM PF02525 YP_001745296.1 identified by match to protein family HMM PF03992 YP_001745297.1 identified by similarity to GB:AAN82214.1; match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001745298.1 identified by match to protein family HMM PF01497 YP_001745299.1 identified by similarity to GB:ABI52625.1; match to protein family HMM PF01032 YP_001745300.1 identified by match to protein family HMM PF01032 YP_001745301.1 identified by similarity to GB:ABI52623.1; match to protein family HMM PF00005 YP_001745302.1 identified by Glimmer3; putative YP_001745303.1 identified by similarity to GB:ABI52622.1; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_001745304.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001745305.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001745306.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413 YP_001745307.1 identified by match to protein family HMM PF06853 YP_001745308.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001745309.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001745311.1 identified by match to protein family HMM PF03738 YP_001745312.1 identified by match to protein family HMM PF05935 YP_001745313.1 identified by similarity to SP:P0AEG4; match to protein family HMM PF01323 YP_001745315.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001745316.1 identified by match to protein family HMM PF02535 YP_001745318.1 DHBP synthase; functions during riboflavin biosynthesis YP_001745319.1 yqiC; identified by match to protein family HMM PF04380 YP_001745320.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_001745321.1 identified by match to protein family HMM PF07290 YP_001745322.1 identified by match to protein family HMM PF01145 YP_001745323.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001745324.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001745325.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235 YP_001745326.1 identified by Glimmer3; putative YP_001745328.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001745329.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001745330.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001745331.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001745332.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol YP_001745333.1 Involved in the tartrate degradation pathway YP_001745334.1 Involved in the tartrate degradation pathway YP_001745335.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_001745336.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001745337.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001745338.1 synthesizes RNA primers at the replication forks YP_001745339.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001745340.1 identified by match to protein family HMM PF08719; match to protein family HMM TIGR02464 YP_001745341.1 identified by similarity to SP:P0A9H1; match to protein family HMM PF03167 YP_001745342.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021 YP_001745343.1 identified by match to protein family HMM PF03551 YP_001745344.1 identified by similarity to SP:P50466; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229 YP_001745345.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_001745346.1 identified by match to protein family HMM PF01588 YP_001745347.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001745348.1 in Escherichia coli this is the second beta-galactosidase system YP_001745349.1 in Escherichia coli this is the second beta-galactosidase system YP_001745350.1 identified by match to protein family HMM PF00324 YP_001745353.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001745354.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_001745355.1 identified by match to protein family HMM PF01863 YP_001745356.1 identified by match to protein family HMM PF02698 YP_001745357.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001745358.1 identified by match to protein family HMM PF03741 YP_001745359.1 involved in the import of serine and threonine coupled with the import of sodium YP_001745361.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666 YP_001745362.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001745363.1 identified by similarity to SP:P0AA78; match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001745364.1 identified by match to protein family HMM PF07434 YP_001745366.1 identified by match to protein family HMM PF04449 YP_001745367.1 identified by similarity to SP:P25732 YP_001745368.1 identified by Glimmer3; putative YP_001745369.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_001745370.1 identified by Glimmer3; putative YP_001745371.1 identified by match to protein family HMM PF09335 YP_001745373.1 identified by match to protein family HMM PF06476 YP_001745374.1 identified by match to protein family HMM PF05957 YP_001745377.1 identified by match to protein family HMM PF07681 YP_001745379.1 identified by match to protein family HMM PF05656 YP_001745380.1 identified by match to protein family HMM PF05656 YP_001745381.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001745382.1 identified by match to protein family HMM PF02678 YP_001745384.1 identified by match to protein family HMM PF06354 YP_001745385.1 identified by match to protein family HMM TIGR00814 YP_001745386.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001745387.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001745388.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001745389.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_001745390.1 involved in the import of threonine and serine in combination with the import of a proton YP_001745391.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_001745392.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_001745393.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon YP_001745394.1 identified by Glimmer3; putative YP_001745395.1 identified by Glimmer3; putative YP_001745396.1 yhaC; identified by similarity to SP:P11864 YP_001745397.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001745398.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_001745399.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_001745400.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001745401.1 identified by Glimmer3; putative YP_001745402.1 identified by Glimmer3; putative YP_001745403.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248 YP_001745406.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_001745407.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_001745408.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport YP_001745409.1 identified by match to protein family HMM PF03609 YP_001745410.1 identified by match to protein family HMM PF03613 YP_001745411.1 identified by match to protein family HMM PF03610 YP_001745412.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_001745413.1 identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815 YP_001745414.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001745415.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_001745416.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_001745417.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001745418.1 identified by similarity to SP:P42912; match to protein family HMM PF01182 YP_001745419.1 yraL; identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_001745420.1 identified by match to protein family HMM PF04348 YP_001745421.1 yraN; identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_001745422.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001745423.1 identified by match to protein family HMM PF04972 YP_001745424.1 identified by match to protein family HMM PF03773 YP_001745425.1 identified by match to protein family HMM PF01370 YP_001745426.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_001745428.1 identified by match to protein family HMM PF01541 YP_001745429.1 identified by match to protein family HMM PF00583 YP_001745430.1 identified by match to protein family HMM PF02036 YP_001745431.1 identified by Glimmer3; putative YP_001745432.1 identified by match to protein family HMM PF01136 YP_001745433.1 identified by match to protein family HMM PF01136 YP_001745434.1 identified by match to protein family HMM PF00296 YP_001745435.1 tryptophan transporter of high affinity YP_001745436.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001745437.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001745438.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726 YP_001745439.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001745440.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001745441.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001745442.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001745443.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001745444.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001745445.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_001745446.1 identified by match to protein family HMM PF00884 YP_001745447.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_001745448.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001745449.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001745450.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001745451.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001745452.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability YP_001745453.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001745454.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001745455.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001745456.1 identified by match to protein family HMM PF00892 YP_001745457.1 involved in the peptidyltransferase reaction during translation YP_001745458.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_001745459.1 identified by match to protein family HMM PF00348 YP_001745460.1 activator of maltose metabolism genes YP_001745461.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001745462.1 identified by match to protein family HMM PF01722 YP_001745464.1 identified by match to protein family HMM PF05494 YP_001745465.1 identified by match to protein family HMM PF02470 YP_001745466.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056 YP_001745467.1 ATP-binding subunit of a putative ABC toluene efflux transporter YP_001745468.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001745469.1 identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_001745470.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001745471.1 identified by match to protein family HMM PF06835 YP_001745472.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001745473.1 identified by match to protein family HMM PF00005 YP_001745474.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001745475.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001745476.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419 YP_001745477.1 identified by match to protein family HMM PF03668 YP_001745478.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001745480.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001745481.1 identified by match to protein family HMM PF01965 YP_001745482.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001745483.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_001745484.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001745485.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001745486.1 identified by match to protein family HMM PF04434 YP_001745488.1 identified by match to protein family HMM PF07728 YP_001745490.1 identified by match to protein family HMM PF05762 YP_001745491.1 identified by Glimmer3; putative YP_001745492.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001745493.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_001745494.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001745495.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891 YP_001745496.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_001745497.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001745498.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic YP_001745499.1 identified by match to protein family HMM PF04386 YP_001745500.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001745501.1 identified by Glimmer3; putative YP_001745502.1 forms a direct contact with the tRNA during translation YP_001745503.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001745504.1 identified by match to protein family HMM PF03969 YP_001745505.1 identified by match to protein family HMM PF06295 YP_001745506.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037 YP_001745507.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038 YP_001745508.1 oxidizes malate to oxaloacetate YP_001745509.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001745510.1 identified by match to protein family HMM PF07338 YP_001745512.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001745513.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001745514.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001745515.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001745516.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001745517.1 yhdP; identified by match to protein family HMM TIGR02099 YP_001745518.1 involved in the processing of the 5'end of 16S rRNA YP_001745519.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001745520.1 part of cell wall structural complex MreBCD; transmembrane component YP_001745521.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001745522.1 functions in MreBCD complex in some organisms YP_001745523.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001745524.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_001745526.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001745527.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001745528.1 identified by match to protein family HMM PF06196 YP_001745529.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001745530.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001745531.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_001745532.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001745533.1 identified by match to protein family HMM PF01555 YP_001745535.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08361 YP_001745536.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001745539.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001745540.1 yhdY; identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001745541.1 identified by match to protein family HMM PF00005 YP_001745543.1 identified by match to protein family HMM PF07369 YP_001745544.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001745545.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_001745546.1 identified by match to protein family HMM PF01396 YP_001745547.1 identified by match to protein family HMM PF04361 YP_001745548.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_001745549.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001745550.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001745551.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001745552.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001745553.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001745554.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001745556.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001745557.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001745558.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001745559.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001745560.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001745561.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001745562.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001745563.1 late assembly protein YP_001745564.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001745565.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001745566.1 binds 5S rRNA along with protein L5 and L25 YP_001745567.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001745568.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001745569.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001745570.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001745571.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001745572.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001745573.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001745574.1 one of the stabilizing components for the large ribosomal subunit YP_001745575.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001745576.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001745577.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001745578.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001745579.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001745580.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001745581.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001745582.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001745583.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001745584.1 identified by match to protein family HMM PF01478 YP_001745585.1 iron storage protein YP_001745586.1 identified by match to protein family HMM PF04324 YP_001745587.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001745588.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001745589.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001745590.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001745591.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001745592.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001745593.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001745594.1 identified by match to protein family HMM PF08348 YP_001745595.1 rotamase YP_001745596.1 identified by match to protein family HMM PF04102 YP_001745597.1 rotamase YP_001745598.1 identified by match to protein family HMM TIGR02443 YP_001745599.1 involved in potassium efflux YP_001745600.1 required for KefB activity YP_001745601.1 identified by match to protein family HMM PF00005 YP_001745602.1 identified by match to protein family HMM PF00561 YP_001745603.1 identified by match to protein family HMM PF06794 YP_001745604.1 identified by match to protein family HMM PF00485 YP_001745605.1 identified by match to protein family HMM PF02566 YP_001745606.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001745607.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667 YP_001745608.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001745609.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001745610.1 identified by match to protein family HMM PF02661 YP_001745611.1 identified by match to protein family HMM PF00160 YP_001745612.1 identified by Glimmer3; putative YP_001745613.1 identified by match to protein family HMM PF07690 YP_001745614.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_001745615.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_001745616.1 member of the FNT family of formate and nitrite transporters YP_001745617.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_001745619.1 identified by similarity to GB:ABF05423.1 YP_001745622.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE) YP_001745623.1 identified by match to protein family HMM PF01676; match to protein family HMM PF08342 YP_001745624.1 identified by match to protein family HMM PF01168 YP_001745627.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001745628.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001745629.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001745630.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_001745631.1 identified by match to protein family HMM PF05036 YP_001745632.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001745633.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001745634.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001745637.1 identified by Glimmer3; putative YP_001745638.1 identified by match to protein family HMM PF05137 YP_001745640.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001745641.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001745642.1 identified by Glimmer3; putative YP_001745643.1 identified by match to protein family HMM PF07095 YP_001745644.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001745645.1 identified by match to protein family HMM PF01479 YP_001745646.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001745648.1 identified by Glimmer3; putative YP_001745649.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001745650.1 identified by similarity to GB:ABA72014.1 YP_001745651.1 yiaG; identified by similarity to GB:CAE16739.1 YP_001745652.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001745653.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001745654.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001745655.1 yhgF; identified by similarity to SP:P46837; match to protein family HMM PF00575 YP_001745656.1 identified by similarity to SP:P0AEL3; match to protein family HMM PF04023 YP_001745657.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_001745658.1 identified by match to protein family HMM PF09012 YP_001745659.1 identified by similarity to GB:AAP19288.1; match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001745660.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_001745661.1 involved in high-affinity gluconate transport YP_001745662.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001745663.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001745664.1 amylomaltase; acts to release glucose from maltodextrins YP_001745665.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001745666.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001745667.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_001745668.1 identified by match to protein family HMM PF01139 YP_001745669.1 identified by match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728 YP_001745670.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001745671.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001745672.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001745673.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001745676.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001745677.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001745678.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001745679.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001745680.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001745681.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001745682.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_001745683.1 identified by match to protein family HMM PF02481 YP_001745684.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614 YP_001745685.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001745686.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001745687.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001745688.1 identified by Glimmer3; putative YP_001745689.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_001745690.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001745691.1 YhhY; regulated by the fur regulator; unknown function YP_001745692.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_001745694.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001745695.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001745696.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001745697.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001745698.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001745699.1 identified by Glimmer3; putative YP_001745701.1 identified by Glimmer3; putative YP_001745702.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001745703.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001745704.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001745705.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001745706.1 identified by match to protein family HMM PF01094 YP_001745707.1 identified by Glimmer3; putative YP_001745708.1 identified by match to protein family HMM PF00583 YP_001745709.1 identified by match to protein family HMM PF01094 YP_001745710.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001745711.1 putative ABC transporter, membrane protein YP_001745712.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001745713.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_001745714.1 catalyzes the methylation of 16S rRNA at position G966 YP_001745715.1 identified by match to protein family HMM PF06611 YP_001745717.1 identified by match to protein family HMM PF07947 YP_001745718.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001745719.1 identified by similarity to GB:ABL00817.1 YP_001745720.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001745721.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697 YP_001745723.1 identified by match to protein family HMM PF07690 YP_001745724.1 identified by match to protein family HMM PF01594 YP_001745725.1 identified by match to protein family HMM PF01648 YP_001745726.1 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294 YP_001745727.1 with NikACDE is involved in nickel transport into the cell YP_001745728.1 with NikABDE is involved in nickel transport into the cell YP_001745729.1 with NikABCE is involved in nickel transport into the cell YP_001745730.1 with NikABCD is involved with nickel transport into the cell YP_001745731.1 Inhibits transcription at high concentrations of nickel YP_001745732.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001745733.1 identified by match to protein family HMM PF00359 YP_001745734.1 identified by similarity to SP:P37188; match to protein family HMM PF02302 YP_001745735.1 identified by match to protein family HMM PF03611 YP_001745736.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001745737.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001745738.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001745739.1 identified by match to protein family HMM PF05534 YP_001745740.1 identified by match to protein family HMM PF01061 YP_001745741.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061 YP_001745742.1 identified by match to protein family HMM PF00529 YP_001745743.1 identified by Glimmer3; putative YP_001745747.1 identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_001745748.1 identified by match to protein family HMM PF01384 YP_001745749.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001745750.1 identified by match to protein family HMM PF00582 YP_001745751.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_001745752.1 predicted SAM-dependent methyltransferase YP_001745753.1 identified by match to protein family HMM PF01432 YP_001745754.1 identified by match to protein family HMM PF04378 YP_001745755.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001745756.1 identified by Glimmer3; putative YP_001745757.1 identified by Glimmer3; putative YP_001745758.1 identified by Glimmer3; putative YP_001745759.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_001745760.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935 YP_001745761.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_001745762.1 identified by match to protein family HMM PF01022 YP_001745763.1 identified by match to protein family HMM PF03773 YP_001745765.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_001745766.1 identified by match to protein family HMM PF00196 YP_001745767.1 identified by similarity to SP:Q56990; match to protein family HMM PF05171 YP_001745768.1 identified by similarity to GB:AAC27809.1; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01785; match to protein family HMM TIGR01786 YP_001745769.1 identified by Glimmer3; putative YP_001745770.1 identified by match to protein family HMM PF01497 YP_001745771.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001745772.1 identified by match to protein family HMM PF06228 YP_001745773.1 identified by similarity to GB:CAG75906.1 YP_001745774.1 identified by match to protein family HMM PF01032 YP_001745775.1 with HmuTU is involved in the transport of hemin YP_001745776.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_001745778.1 inactive form YP_001745781.1 identified by Glimmer3; putative YP_001745782.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds YP_001745783.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001745784.1 identified by match to protein family HMM PF00165 YP_001745785.1 regulates genes in response to acid and/or during stationary phase YP_001745786.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_001745787.1 identified by match to protein family HMM PF03150 YP_001745788.1 identified by Glimmer3; putative YP_001745789.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_001745790.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281 YP_001745791.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001745792.1 yhjD; identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766 YP_001745793.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001745794.1 identified by match to protein family HMM PF05170 YP_001745795.1 in Escherichia coli this protein is involved in flagellar function YP_001745796.1 identified by Glimmer3; putative YP_001745797.1 identified by match to protein family HMM PF00294 YP_001745798.1 identified by similarity to GB:CAK15512.1 YP_001745799.1 identified by similarity to GB:AAY95391.1 YP_001745801.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001745802.1 involved in the transport of C4-dicarboxylates across the membrane YP_001745803.1 identified by Glimmer3; putative YP_001745804.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli YP_001745805.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_001745806.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001745807.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001745808.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_001745809.1 identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371 YP_001745811.1 identified by match to protein family HMM TIGR03369 YP_001745813.1 identified by match to protein family HMM TIGR03368 YP_001745814.1 identified by similarity to RF:NP_458295.1 YP_001745815.1 identified by Glimmer3; putative YP_001745817.1 identified by Glimmer3; putative YP_001745818.1 identified by Glimmer3; putative YP_001745819.1 identified by Glimmer3; putative YP_001745821.1 identified by Glimmer3; putative YP_001745823.1 identified by Glimmer3; putative YP_001745824.1 identified by match to protein family HMM TIGR00814 YP_001745825.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001745826.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001745827.1 identified by match to protein family HMM PF00528 YP_001745828.1 transports peptides consisting of two or three amino acids YP_001745829.1 identified by Glimmer3; putative YP_001745830.1 identified by match to protein family HMM PF00496 YP_001745831.1 identified by Glimmer3; putative YP_001745832.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001745833.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890 YP_001745835.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine YP_001745836.1 identified by match to protein family HMM PF00583 YP_001745837.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509 YP_001745838.1 identified by match to protein family HMM PF00691; match to protein family HMM PF05433 YP_001745839.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001745842.1 identified by match to protein family HMM PF00313 YP_001745843.1 identified by match to protein family HMM PF01848 YP_001745845.1 identified by match to protein family HMM PF00665 YP_001745846.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001745847.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001745850.1 identified by match to protein family HMM PF05360 YP_001745851.1 identified by match to protein family HMM PF05360 YP_001745852.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312 YP_001745853.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001745854.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_001745855.1 with XylFH is part of the high affinity xylose ABC transporter YP_001745856.1 identified by match to protein family HMM PF02653 YP_001745857.1 identified by match to protein family HMM PF00165 YP_001745858.1 identified by match to protein family HMM PF01832 YP_001745859.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001745860.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001745861.1 identified by match to protein family HMM PF00037 YP_001745862.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001745863.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_001745864.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001745865.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO YP_001745866.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001745867.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001745868.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001745869.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_001745870.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001745871.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001745872.1 identified by match to protein family HMM PF00165 YP_001745873.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_001745874.1 identified by similarity to GB:CAD07947.1; match to protein family HMM PF07944 YP_001745875.1 identified by match to protein family HMM PF06629 YP_001745876.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001745877.1 identified by match to protein family HMM PF00529 YP_001745879.1 identified by Glimmer3; putative YP_001745880.1 identified by match to protein family HMM PF00171 YP_001745881.1 identified by match to protein family HMM PF02661 YP_001745882.1 identified by match to protein family HMM PF00465 YP_001745883.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475 YP_001745884.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001745885.1 yibF; identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001745886.1 identified by match to protein family HMM PF02395; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001745887.1 identified by similarity to SP:P20862 YP_001745890.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001745891.1 identified by match to protein family HMM PF00577 YP_001745892.1 identified by match to protein family HMM PF00419 YP_001745893.1 identified by match to protein family HMM PF08281 YP_001745894.1 identified by match to protein family HMM PF00165 YP_001745895.1 identified by match to protein family HMM PF00529 YP_001745897.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_001745898.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001745899.1 Acts as a repressor of the mtlAD operon YP_001745902.1 identified by Glimmer3; putative YP_001745904.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662 YP_001745905.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_001745906.1 represses the lctPRD operon YP_001745907.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001745908.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_001745909.1 catalyzes the O-acetylation of serine YP_001745910.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001745911.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001745912.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02181 YP_001745913.1 identified by match to protein family HMM PF00581 YP_001745914.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001745915.1 identified by match to protein family HMM PF01551 YP_001745916.1 identified by match to protein family HMM PF04748 YP_001745917.1 identified by match to protein family HMM PF00535 YP_001745918.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001745919.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001745920.1 identified by Glimmer3; putative YP_001745921.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001745922.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001745923.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193 YP_001745924.1 identified by match to protein family HMM PF04932 YP_001745925.1 identified by match to protein family HMM PF00535 YP_001745926.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001745927.1 identified by match to protein family HMM PF06176 YP_001745928.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001745929.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001745930.1 identified by match to protein family HMM PF06293 YP_001745931.1 identified by match to protein family HMM PF00534 YP_001745932.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02201 YP_001745933.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001745934.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001745935.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001745936.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001745937.1 required for 70S ribosome assembly YP_001745938.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001745939.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001745940.1 catalyzes the formation of dUMP from dUTP YP_001745941.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001745942.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001745943.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001745944.1 yicC; identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_001745945.1 identified by similarity to SP:P23840 YP_001745946.1 identified by match to protein family HMM PF03458 YP_001745947.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001745948.1 Essential for recycling GMP and indirectly, cGMP YP_001745949.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001745950.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_001745951.1 specifically modifies tRNA at position G18 YP_001745952.1 catalyzes branch migration in Holliday junction intermediates YP_001745953.1 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210 YP_001745954.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001745955.1 identified by match to protein family HMM PF05170 YP_001745956.1 identified by similarity to GB:CAH23042.1; match to protein family HMM PF07385 YP_001745957.1 identified by match to protein family HMM PF00480 YP_001745958.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167 YP_001745959.1 identified by match to protein family HMM PF01116 YP_001745960.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848 YP_001745961.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_001745962.1 identified by Glimmer3; putative YP_001745963.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_001745964.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_001745965.1 identified by match to protein family HMM PF00589 YP_001745966.1 identified by Glimmer3; putative YP_001745967.1 identified by match to protein family HMM PF07455 YP_001745968.1 identified by similarity to SP:P05461 YP_001745969.1 identified by match to protein family HMM PF05930 YP_001745970.1 identified by similarity to SP:P05462 YP_001745971.1 identified by similarity to SP:P05463 YP_001745972.1 identified by similarity to SP:P68663 YP_001745973.1 identified by similarity to SP:P68665 YP_001745974.1 identified by match to protein family HMM PF01751; match to protein family HMM PF03288; match to protein family HMM PF08273; match to protein family HMM PF08706; match to protein family HMM TIGR01613 YP_001745975.1 identified by Glimmer3; putative YP_001745976.1 identified by Glimmer3; putative YP_001745977.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001745978.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001745979.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_001745980.1 identified by similarity to SP:Q7CPG1 YP_001745981.1 identified by match to protein family HMM PF07720; match to protein family HMM TIGR02552 YP_001745982.1 identified by Glimmer3; putative YP_001745984.1 identified by Glimmer3; putative YP_001745986.1 Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system YP_001745987.1 identified by similarity to SP:P11922; match to protein family HMM PF02369 YP_001745988.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS YP_001745989.1 identified by similarity to GB:CAE16839.1; match to protein family HMM PF06296 YP_001745990.1 identified by match to protein family HMM PF01381 YP_001745991.1 identified by match to protein family HMM PF06711 YP_001745992.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001745993.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_001745994.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_001745995.1 membrane protein regulates uhpT expression YP_001745996.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_001745997.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_001745998.1 identified by Glimmer3; putative YP_001745999.1 identified by Glimmer3; putative YP_001746000.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_001746001.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_001746002.1 multidrug efflux protein involved in adaptation to low energy shock YP_001746005.1 identified by match to protein family HMM PF02656 YP_001746006.1 identified by match to protein family HMM PF00884 YP_001746007.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function YP_001746008.1 identified by match to protein family HMM PF00165 YP_001746009.1 identified by match to protein family HMM PF02056 YP_001746010.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005 YP_001746011.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001746012.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_001746013.1 identified by Glimmer3; putative YP_001746014.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_001746015.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001746016.1 identified by match to protein family HMM PF07119 YP_001746018.1 FAD/NAD(P)-binding domain YP_001746019.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893 YP_001746020.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001746021.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001746022.1 identified by similarity to SP:P31459; match to protein family HMM PF05035 YP_001746023.1 identified by similarity to SP:P31460; match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001746025.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001746026.1 identified by match to protein family HMM PF06078 YP_001746027.1 negatively supercoils closed circular double-stranded DNA YP_001746028.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001746029.1 binds the polymerase to DNA and acts as a sliding clamp YP_001746030.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001746031.1 identified by Glimmer3; putative YP_001746032.1 identified by Glimmer3; putative YP_001746033.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001746034.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001746035.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001746036.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001746037.1 identified by similarity to SP:P0AD89; match to protein family HMM TIGR02616 YP_001746038.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_001746039.1 Confers resistance to chloramphenicol YP_001746040.1 Involved in anaerobic NO protection YP_001746042.1 identified by match to protein family HMM PF03358 YP_001746043.1 identified by match to protein family HMM PF00860 YP_001746044.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_001746045.1 identified by similarity to GB:ABB63945.1 YP_001746046.1 identified by Glimmer3; putative YP_001746047.1 identified by similarity to GB:ABG83000.1 YP_001746048.1 identified by similarity to GB:ABB63945.1 YP_001746049.1 identified by Glimmer3; putative YP_001746050.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001746051.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001746052.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001746053.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001746054.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975 YP_001746055.1 identified by similarity to GB:AAL18164.1 YP_001746056.1 identified by similarity to GB:AAL18163.1; match to protein family HMM PF00577 YP_001746057.1 identified by similarity to GB:AAL18162.1; match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001746058.1 identified by match to protein family HMM PF00419 YP_001746059.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001746060.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001746061.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001746062.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001746063.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001746064.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001746065.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001746066.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001746067.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001746068.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001746069.1 identified by match to protein family HMM PF03899 YP_001746070.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001746071.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001746072.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001746073.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001746074.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001746075.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001746076.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001746077.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001746078.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001746079.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001746080.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001746081.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001746082.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001746083.1 DNA-binding transcriptional repressor of ribose metabolism YP_001746084.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001746085.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001746086.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001746087.1 identified by match to protein family HMM PF04219 YP_001746088.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function YP_001746089.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001746091.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001746092.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001746093.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001746094.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001746095.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001746096.1 identified by match to protein family HMM PF00639 YP_001746097.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001746098.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001746099.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001746100.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001746101.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001746102.1 identified by Glimmer3; putative YP_001746103.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380 YP_001746104.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001746105.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_001746106.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001746107.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_001746108.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_001746109.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382 YP_001746110.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001746111.1 identified by match to protein family HMM PF01943 YP_001746112.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001746113.1 enterobacterial common antigen polymerase YP_001746114.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_001746115.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_001746116.1 identified by match to protein family HMM PF04055 YP_001746117.1 identified by similarity to SP:P25549; match to protein family HMM PF00884 YP_001746118.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540 YP_001746119.1 identified by match to protein family HMM PF04375 YP_001746120.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_001746121.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001746122.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001746123.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001746126.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001746127.1 identified by match to protein family HMM PF04340 YP_001746128.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001746129.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_001746130.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001746131.1 identified by match to protein family HMM PF01887 YP_001746133.1 identified by Glimmer3; putative YP_001746134.1 responsible for the influx of magnesium ions YP_001746135.1 identified by match to protein family HMM PF06092 YP_001746136.1 identified by match to protein family HMM TIGR03034 YP_001746137.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_001746138.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001746139.1 catalyzes the hydrolysis of phosphatidylcholine YP_001746140.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001746141.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001746142.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001746143.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001746144.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001746145.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001746146.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001746147.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001746148.1 identified by match to protein family HMM PF02133 YP_001746149.1 identified by similarity to RF:NP_756622.1 YP_001746150.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001746151.1 identified by match to protein family HMM PF06545 YP_001746152.1 identified by match to protein family HMM PF06263 YP_001746153.1 identified by similarity to GB:AAZ87092.1 YP_001746154.1 identified by match to protein family HMM PF00857 YP_001746155.1 identified by Glimmer3; putative YP_001746156.1 identified by Glimmer3; putative YP_001746157.1 identified by match to protein family HMM PF01738 YP_001746158.1 identified by Glimmer3; putative YP_001746159.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001746160.1 identified by match to protein family HMM PF01970 YP_001746161.1 identified by Glimmer3; putative YP_001746162.1 identified by match to protein family HMM PF03401 YP_001746163.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001746164.1 identified by similarity to SP:P31459; match to protein family HMM PF05035 YP_001746165.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001746166.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_001746167.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001746168.1 identified by match to protein family HMM PF06843 YP_001746169.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001746170.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001746171.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001746172.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001746173.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001746174.1 identified by match to protein family HMM PF02357; match to protein family HMM TIGR01955 YP_001746175.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001746176.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001746177.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001746178.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001746179.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001746180.1 yigZ; identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_001746181.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_001746182.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_001746183.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_001746184.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001746185.1 identified by match to protein family HMM PF06288 YP_001746186.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001746187.1 identified by similarity to SP:P0AEG4; match to protein family HMM PF01323 YP_001746188.1 identified by Glimmer3; putative YP_001746189.1 identified by match to protein family HMM PF01553 YP_001746190.1 identified by Glimmer3; putative YP_001746191.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001746192.1 identified by Glimmer3; putative YP_001746193.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001746194.1 identified by match to protein family HMM PF04220 YP_001746195.1 identified by Glimmer3; putative YP_001746196.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001746197.1 identified by Glimmer3; putative YP_001746198.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001746199.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001746200.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001746201.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_001746202.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001746203.1 identified by match to protein family HMM PF01261 YP_001746204.1 identified by match to protein family HMM PF07690 YP_001746205.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown YP_001746206.1 identified by match to protein family HMM TIGR00792 YP_001746207.1 identified by match to protein family HMM TIGR00792 YP_001746208.1 identified by match to protein family HMM PF01055 YP_001746209.1 identified by match to protein family HMM PF01263 YP_001746210.1 identified by match to protein family HMM PF07221 YP_001746211.1 identified by match to protein family HMM PF01791 YP_001746212.1 identified by match to protein family HMM PF03446 YP_001746213.1 identified by match to protein family HMM PF00294 YP_001746214.1 identified by match to protein family HMM PF00455; match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001746215.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001746216.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001746217.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001746218.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02447 YP_001746219.1 identified by Glimmer3; putative YP_001746220.1 identified by match to protein family HMM PF01402 YP_001746222.1 required for the formation of active formate dehydrogenase YP_001746223.1 cytochrome b556(FDO) component; heme containing YP_001746224.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_001746225.1 Selenoprotein. identified by similarity to SP:P32176; match to protein family HMM PF04879; match to protein family HMM TIGR01409 YP_001746226.1 identified by Glimmer3; putative YP_001746227.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001746228.1 identified by Glimmer3; putative YP_001746229.1 identified by similarity to GB:CAJ22947.1 YP_001746230.1 identified by similarity to GB:ABJ10234.1 YP_001746232.1 putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system YP_001746233.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars YP_001746234.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427 YP_001746235.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system YP_001746236.1 identified by similarity to GB:AAB71432.1 YP_001746237.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625 YP_001746238.1 identified by match to protein family HMM PF00596; match to protein family HMM TIGR02624 YP_001746239.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_001746240.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_001746241.1 identified by Glimmer3; putative YP_001746242.1 activates the expression of the rhaBAD operon and rhaT gene YP_001746243.1 activates the expression of rhaRS in response to L-rhamnose YP_001746244.1 transports L-rhamnose and L-lyxose into the cell YP_001746245.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_001746247.1 transports degraded pectin products into the bacterial cell YP_001746248.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_001746249.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001746250.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001746251.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_001746252.1 identified by match to protein family HMM PF00589 YP_001746253.1 identified by similarity to SP:P07695 YP_001746254.1 identified by similarity to GB:AAP04469.1 YP_001746258.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_001746260.1 identified by similarity to SP:Q06419; match to protein family HMM PF05840 YP_001746261.1 identified by similarity to GB:AAP04476.1 YP_001746262.1 identified by Glimmer3; putative YP_001746263.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_001746264.1 identified by similarity to GB:AAN28261.1 YP_001746265.1 identified by similarity to GB:AAN28262.1 YP_001746266.1 identified by Glimmer3; putative YP_001746267.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540 YP_001746268.1 identified by similarity to SP:P25479; match to protein family HMM PF03237; match to protein family HMM PF06056 YP_001746269.1 identified by match to protein family HMM PF05929 YP_001746270.1 identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551 YP_001746271.1 identified by similarity to SP:P25476; match to protein family HMM PF05944 YP_001746272.1 identified by similarity to SP:P25475; match to protein family HMM PF05926 YP_001746273.1 identified by similarity to SP:P51772; match to protein family HMM PF05489 YP_001746274.1 identified by similarity to SP:P51773; match to protein family HMM PF04550 YP_001746275.1 identified by match to protein family HMM PF00959 YP_001746276.1 identified by similarity to SP:P51769 YP_001746277.1 identified by similarity to SP:P51770 YP_001746278.1 identified by similarity to GB:AAM83596.1 YP_001746279.1 identified by match to protein family HMM PF06891 YP_001746280.1 identified by match to protein family HMM PF05069; match to protein family HMM TIGR01635 YP_001746281.1 identified by similarity to SP:P36935 YP_001746282.1 identified by similarity to SP:P31340; match to protein family HMM PF04717; match to protein family HMM TIGR01644 YP_001746283.1 identified by similarity to SP:P51768; match to protein family HMM PF04965 YP_001746284.1 identified by match to protein family HMM PF04865 YP_001746285.1 identified by match to protein family HMM TIGR01634 YP_001746286.1 identified by match to protein family HMM PF03406 YP_001746287.1 identified by similarity to SP:P26699; match to protein family HMM PF02413 YP_001746288.1 identified by similarity to GB:ABM26356.1 YP_001746289.1 identified by Glimmer3; putative YP_001746290.1 identified by match to protein family HMM PF04984 YP_001746291.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611 YP_001746292.1 identified by match to protein family HMM PF06158 YP_001746293.1 identified by match to protein family HMM PF06528 YP_001746294.1 identified by match to protein family HMM TIGR01760 YP_001746295.1 identified by match to protein family HMM PF06995 YP_001746296.1 identified by match to protein family HMM PF05954 YP_001746297.1 in E. coli K-12 this is in prophage P2 remnant YP_001746298.1 identified by match to protein family HMM PF01609 YP_001746299.1 identified by Glimmer3; putative YP_001746300.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001746301.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001746302.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_001746303.1 identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672 YP_001746304.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001746305.1 identified by match to protein family HMM PF07305 YP_001746306.1 identified by match to protein family HMM PF05656 YP_001746307.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_001746308.1 with UspC and Usp E is involved in resistance to UV radiation YP_001746309.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001746310.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001746311.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001746312.1 identified by similarity to SP:P0AER0; match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_001746313.1 identified by match to protein family HMM PF06005 YP_001746314.1 identified by Glimmer3; putative YP_001746315.1 identified by Glimmer3; putative YP_001746316.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001746317.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001746318.1 heat shock protein involved in degradation of misfolded proteins YP_001746319.1 heat shock protein involved in degradation of misfolded proteins YP_001746320.1 identified by match to protein family HMM PF05036; match to protein family HMM TIGR02223 YP_001746321.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001746322.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001746323.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001746324.1 member of the NlpC/P60 superfamily of peptidases YP_001746325.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001746326.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001746327.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001746328.1 identified by Glimmer3; putative YP_001746329.1 identified by similarity to SP:P40786; match to protein family HMM PF03502 YP_001746330.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_001746331.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_001746332.1 identified by similarity to GB:CAD09521.1 YP_001746333.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_001746334.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001746335.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_001746336.1 identified by match to protein family HMM PF00892 YP_001746337.1 identified by match to protein family HMM PF06940 YP_001746338.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001746339.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001746340.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_001746341.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_001746342.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_001746343.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_001746344.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001746345.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_001746346.1 identified by match to protein family HMM PF00165 YP_001746347.1 identified by match to protein family HMM PF00884 YP_001746348.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001746349.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001746350.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001746351.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001746352.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001746353.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001746354.1 catalyzes the conversion of NADPH to NADH YP_001746355.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001746356.1 identified by match to protein family HMM PF07226 YP_001746357.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001746358.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_001746359.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001746360.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001746361.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001746362.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001746363.1 identified by similarity to GB:BAC18512.1 YP_001746364.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001746365.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001746366.1 Modulates Rho-dependent transcription termination YP_001746367.1 binds directly to 23S ribosomal RNA YP_001746368.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001746369.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001746370.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001746371.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001746372.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001746373.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001746374.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001746375.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001746376.1 identified by match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356 YP_001746377.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001746378.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001746379.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001746380.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001746381.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001746382.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001746383.1 identified by match to protein family HMM PF04222 YP_001746384.1 histone-like DNA-binding protein YP_001746385.1 identified by match to protein family HMM PF07356 YP_001746387.1 identified by Glimmer3; putative YP_001746388.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001746389.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_001746390.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001746391.1 involved in de novo purine biosynthesis YP_001746392.1 identified by Glimmer3; putative YP_001746393.1 identified by match to protein family HMM PF01527 YP_001746394.1 identified by match to protein family HMM PF00665 YP_001746395.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001746396.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001746397.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_001746398.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001746399.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_001746400.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001746401.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013 YP_001746402.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001746403.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001746404.1 identified by similarity to SP:P37084; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001746405.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828 YP_001746406.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_001746407.1 identified by match to protein family HMM PF03830; match to protein family HMM TIGR00854 YP_001746408.1 identified by match to protein family HMM PF03610; match to protein family HMM TIGR00824 YP_001746409.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate YP_001746410.1 identified by similarity to SP:P37078; match to protein family HMM PF04198 YP_001746411.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001746413.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001746414.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001746417.1 identified by match to protein family HMM PF06251 YP_001746418.1 identified by match to protein family HMM PF06082 YP_001746420.1 identified by Glimmer3; putative YP_001746421.1 identified by match to protein family HMM PF06146 YP_001746422.1 with MalKFE is involved in the transport of maltose into the cell YP_001746423.1 with MalKGE is involved in maltose transport into the cell YP_001746424.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001746425.1 with malEFG is involved in import of maltose/maltodextrin YP_001746426.1 porin involved in the transport of maltose and maltodextrins YP_001746427.1 identified by match to protein family HMM PF07148 YP_001746428.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations YP_001746429.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001746430.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001746431.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001746432.1 identified by match to protein family HMM PF01219 YP_001746433.1 Represses a number of genes involved in the response to DNA damage YP_001746434.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001746435.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_001746436.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_001746437.1 identified by similarity to GB:ABB68502.1 YP_001746438.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00742 YP_001746439.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_001746440.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001746441.1 unwinds double stranded DNA YP_001746442.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001746443.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001746445.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_001746446.1 yjbQ; identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149 YP_001746447.1 identified by match to protein family HMM PF04237 YP_001746448.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001746449.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_001746451.1 identified by match to protein family HMM PF00563 YP_001746452.1 regulates genes involved in response to oxidative stress YP_001746453.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950 YP_001746454.1 identified by Glimmer3; putative YP_001746455.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001746456.1 yjcE; identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831 YP_001746457.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001746458.1 identified by match to protein family HMM PF04341 YP_001746459.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001746460.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001746461.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_001746462.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149 YP_001746463.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148 YP_001746464.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_001746465.1 identified by match to protein family HMM PF03918; match to protein family HMM TIGR03147 YP_001746466.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001746467.1 identified by Glimmer3; putative YP_001746468.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_001746469.1 identified by match to protein family HMM PF08238 YP_001746470.1 Selenoprotein. identified by similarity to SP:P07658; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591 YP_001746471.1 identified by Glimmer3; putative YP_001746472.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_001746473.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001746474.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001746476.1 identified by Glimmer3; putative YP_001746477.1 identified by match to protein family HMM PF00753 YP_001746478.1 identified by similarity to SP:P32718; match to protein family HMM PF00480 YP_001746479.1 identified by similarity to SP:P32719; match to protein family HMM PF00834 YP_001746480.1 identified by similarity to SP:P32720; match to protein family HMM PF02653 YP_001746481.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains YP_001746482.1 identified by similarity to SP:P39265; match to protein family HMM PF00532 YP_001746483.1 involved in rpiB and als operon repression YP_001746484.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001746486.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001746487.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_001746488.1 identified by match to protein family HMM TIGR02322 YP_001746489.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318 YP_001746490.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02324 YP_001746491.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323 YP_001746492.1 identified by match to protein family HMM PF06007 YP_001746493.1 identified by match to protein family HMM PF05861 YP_001746494.1 identified by match to protein family HMM PF05845; match to protein family HMM TIGR03292 YP_001746495.1 identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293 YP_001746496.1 may be involved in phosphonate uptake and biodegradation YP_001746497.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_001746498.1 identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431 YP_001746499.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315 YP_001746500.1 identified by match to protein family HMM PF00903 YP_001746501.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_001746504.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883 YP_001746505.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001746506.1 response regulator in two-component regulatory system with BasS YP_001746507.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001746508.1 identified by match to protein family HMM PF00324 YP_001746509.1 identified by match to protein family HMM PF00165 YP_001746510.1 identified by Glimmer3; putative YP_001746511.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001746512.1 identified by match to protein family HMM PF00165 YP_001746513.1 identified by match to protein family HMM PF02056 YP_001746514.1 identified by match to protein family HMM TIGR00792 YP_001746516.1 identified by similarity to SP:P14407; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001746517.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001746518.1 identified by Glimmer3; putative YP_001746519.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_001746520.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_001746521.1 identified by Glimmer3; putative YP_001746522.1 identified by match to protein family HMM PF06902 YP_001746524.1 identified by Glimmer3; putative YP_001746526.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001746527.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_001746528.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001746529.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_001746530.1 regulates the cadBA operon YP_001746531.1 identified by match to protein family HMM PF00440 YP_001746532.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001746533.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_001746534.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001746535.1 catalyzes the formation of fumarate from aspartate YP_001746536.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001746537.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001746538.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001746539.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001746542.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_001746543.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001746544.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex YP_001746545.1 identified by similarity to SP:P0ADB7; match to protein family HMM PF08085 YP_001746546.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_001746547.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001746548.1 identified by match to protein family HMM PF00144 YP_001746549.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001746550.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001746551.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001746552.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001746553.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001746554.1 identified by match to protein family HMM PF00324 YP_001746555.1 identified by Glimmer3; putative YP_001746556.1 identified by similarity to SP:P39284 YP_001746557.1 identified by match to protein family HMM PF00924 YP_001746558.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001746559.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001746560.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001746561.1 identified by match to protein family HMM PF00037; match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_001746562.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_001746563.1 possibly involved in cell wall synthesis YP_001746564.1 identified by similarity to SP:P26365; match to protein family HMM PF01520 YP_001746565.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001746566.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001746567.1 Stimulates the elongation of poly(A) tails YP_001746568.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001746569.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001746570.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001746572.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001746573.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001746574.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001746575.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001746577.1 identified by match to protein family HMM PF04012 YP_001746579.1 identified by match to protein family HMM PF03994 YP_001746580.1 identified by match to protein family HMM PF06693 YP_001746581.1 identified by match to protein family HMM PF03738 YP_001746582.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_001746583.1 identified by match to protein family HMM PF07338 YP_001746584.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_001746585.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001746586.1 negative regulator of ulaG and ulaABCDEF YP_001746588.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001746589.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001746590.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001746591.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_001746592.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_001746593.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001746594.1 identified by match to protein family HMM PF07338 YP_001746595.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001746596.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001746597.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001746598.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001746599.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001746600.1 identified by match to protein family HMM PF04290 YP_001746601.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001746602.1 identified by match to protein family HMM PF01144 YP_001746603.1 identified by match to protein family HMM PF00378 YP_001746604.1 identified by match to protein family HMM PF01261 YP_001746605.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001746606.1 identified by match to protein family HMM PF00440 YP_001746607.1 identified by match to protein family HMM PF04225; match to protein family HMM PF08525 YP_001746608.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001746609.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001746610.1 identified by similarity to GB:CAD06876.1 YP_001746611.1 identified by similarity to GB:CAD06877.1 YP_001746612.1 Involved in anaerobic NO protection and iron metabolism YP_001746613.1 identified by match to protein family HMM PF00892 YP_001746614.1 identified by match to protein family HMM PF01073; match to protein family HMM PF05368 YP_001746615.1 identified by match to protein family HMM PF01638 YP_001746616.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001746617.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001746618.1 identified by match to protein family HMM TIGR01626 YP_001746619.1 identified by match to protein family HMM PF06526 YP_001746620.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001746621.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001746622.1 identified by Glimmer3; putative YP_001746623.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244 YP_001746624.1 identified by match to protein family HMM PF04357 YP_001746625.1 identified by match to protein family HMM PF03674 YP_001746626.1 part of the toxin-antitoxin ChpB-ChpS system YP_001746627.1 toxin of the ChpB-ChpS toxin-antitoxin system YP_001746628.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001746629.1 identified by match to protein family HMM PF00532 YP_001746630.1 identified by match to protein family HMM PF00005 YP_001746631.1 identified by match to protein family HMM PF02653 YP_001746632.1 membrane component of a putative sugar ABC transporter system YP_001746633.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001746635.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081 YP_001746636.1 yjgA; identified by match to protein family HMM PF04751 YP_001746637.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001746638.1 identified by match to protein family HMM PF07361 YP_001746639.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_001746640.1 identified by similarity to SP:P0C077; match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_001746641.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001746642.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001746643.1 identified by Glimmer3; putative YP_001746644.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_001746645.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001746646.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_001746647.1 P-type ATPase involved in magnesium influx YP_001746648.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001746649.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001746650.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001746651.1 identified by Glimmer3; putative YP_001746652.1 identified by match to protein family HMM PF01042 YP_001746653.1 identified by match to protein family HMM PF00106 YP_001746654.1 identified by match to protein family HMM PF00440 YP_001746655.1 identified by Glimmer3; putative YP_001746656.1 yjgK; identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001746657.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_001746658.1 identified by match to protein family HMM PF06877 YP_001746659.1 identified by match to protein family HMM PF00583 YP_001746660.1 identified by match to protein family HMM PF05987 YP_001746661.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001746662.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001746663.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001746664.1 identified by Glimmer3; putative YP_001746665.1 identified by match to protein family HMM PF03739 YP_001746666.1 identified by match to protein family HMM PF03739 YP_001746667.1 identified by match to protein family HMM PF05872 YP_001746668.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001746669.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00791 YP_001746670.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001746671.1 NAD-binding YP_001746672.1 identified by match to protein family HMM PF01202; match to protein family HMM TIGR01313 YP_001746673.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001746674.1 identified by match to protein family HMM PF00589 YP_001746675.1 yjgX; identified by match to protein family HMM PF00884 YP_001746676.1 identified by similarity to GB:AAC13751.1; match to protein family HMM PF01389; match to protein family HMM PF01617 YP_001746677.1 identified by match to protein family HMM PF03400 YP_001746679.1 identified by match to protein family HMM PF04221 YP_001746680.1 identified by match to protein family HMM PF02384 YP_001746681.1 identified by match to protein family HMM PF01420 YP_001746682.1 identified by match to protein family HMM PF04313; match to protein family HMM PF04851 YP_001746683.1 identified by similarity to GB:AAW89424.1 YP_001746684.1 identified by similarity to GB:AAW89425.1 YP_001746685.1 identified by similarity to GB:AAL22613.1 YP_001746686.1 identified by Glimmer3; putative YP_001746687.1 identified by Glimmer3; putative YP_001746688.1 identified by Glimmer3; putative YP_001746689.1 identified by similarity to GB:AAT68662.1 YP_001746690.1 identified by match to protein family HMM PF00665 YP_001746691.1 identified by match to protein family HMM PF01527 YP_001746692.1 identified by Glimmer3; putative YP_001746694.1 identified by match to protein family HMM PF01609 YP_001746695.1 identified by similarity to GB:AAM31897.1 YP_001746696.1 identified by similarity to GB:ABE29579.1 YP_001746697.1 identified by Glimmer3; putative YP_001746698.1 identified by Glimmer3; putative YP_001746699.1 identified by match to protein family HMM PF05930 YP_001746700.1 identified by Glimmer3; putative YP_001746701.1 identified by similarity to GB:CAG75762.1 YP_001746702.1 identified by match to protein family HMM PF00816 YP_001746703.1 identified by similarity to GB:ABB74995.1 YP_001746705.1 identified by match to protein family HMM PF00665 YP_001746706.1 identified by Glimmer3; putative YP_001746708.1 identified by Glimmer3; putative YP_001746709.1 identified by Glimmer3; putative YP_001746710.1 identified by Glimmer3; putative YP_001746711.1 identified by match to protein family HMM PF01926 YP_001746712.1 identified by Glimmer3; putative YP_001746713.1 identified by match to protein family HMM PF08279 YP_001746714.1 identified by Glimmer3; putative YP_001746716.1 yafZ; identified by match to protein family HMM PF06067 YP_001746717.1 identified by match to protein family HMM PF03230 YP_001746718.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001746719.1 identified by match to protein family HMM PF06174 YP_001746720.1 identified by match to protein family HMM PF06154 YP_001746721.1 identified by match to protein family HMM PF06755 YP_001746723.1 identified by match to protein family HMM PF06117 YP_001746725.1 identified by Glimmer3; putative YP_001746726.1 identified by Glimmer3; putative YP_001746727.1 identified by Glimmer3; putative YP_001746731.1 identified by Glimmer3; putative YP_001746732.1 identified by match to protein family HMM PF01844 YP_001746737.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_001746738.1 identified by Glimmer3; putative YP_001746739.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_001746740.1 identified by similarity to GB:ABK43865.1 YP_001746741.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_001746742.1 identified by match to protein family HMM PF00580 YP_001746743.1 identified by similarity to GB:CAJ67303.1 YP_001746744.1 identified by Glimmer3; putative YP_001746745.1 identified by match to protein family HMM PF03629 YP_001746746.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646; match to protein family HMM TIGR03547 YP_001746747.1 identified by similarity to SP:P69856; match to protein family HMM PF06178 YP_001746748.1 identified by Glimmer3; putative YP_001746749.1 inversion of on/off regulator of fimA YP_001746750.1 inversion of on/off regulator of fimA YP_001746751.1 identified by match to protein family HMM PF00419 YP_001746752.1 identified by match to protein family HMM PF00419 YP_001746753.1 identified by Glimmer3; putative YP_001746754.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001746755.1 identified by match to protein family HMM PF00577 YP_001746756.1 identified by match to protein family HMM PF00419 YP_001746757.1 identified by match to protein family HMM PF00419 YP_001746758.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160 YP_001746759.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001746760.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001746761.1 identified by similarity to SP:P39160; match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001746762.1 regulates the expression of uxuBA YP_001746764.1 identified by Glimmer3; putative YP_001746765.1 identified by Glimmer3; putative YP_001746766.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_001746767.1 identified by match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF03610; match to protein family HMM PF05524; match to protein family HMM TIGR01003; match to protein family HMM TIGR01417; match to protein family HMM TIGR02364 YP_001746768.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_001746769.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001746770.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001746771.1 identified by similarity to GB:AAL61900.1; match to protein family HMM PF07690 YP_001746772.1 identified by similarity to GB:AAL61901.1; match to protein family HMM PF01266 YP_001746773.1 identified by similarity to GB:AAL61902.1; match to protein family HMM PF02028 YP_001746774.1 identified by similarity to GB:AAL61903.1; match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001746775.1 identified by similarity to GB:AAL61904.1; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR01505 YP_001746776.1 identified by similarity to GB:AAL61906.1; match to protein family HMM PF01261; match to protein family HMM TIGR03234 YP_001746777.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001746778.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_001746779.1 identified by similarity to GB:AAL61901.1; match to protein family HMM PF01266 YP_001746780.1 identified by similarity to GB:AAL61908.1; match to protein family HMM PF03553; match to protein family HMM TIGR00931 YP_001746781.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001746782.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975 YP_001746783.1 identified by match to protein family HMM PF07670 YP_001746784.1 identified by match to protein family HMM PF07670 YP_001746785.1 identified by Glimmer3; putative YP_001746786.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown YP_001746787.1 identified by match to protein family HMM PF02369 YP_001746788.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690 YP_001746789.1 identified by match to protein family HMM PF06977 YP_001746790.1 identified by match to protein family HMM PF00805 YP_001746791.1 identified by similarity to GB:ABC78983.1 YP_001746792.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241 YP_001746793.1 identified by match to protein family HMM PF06050 YP_001746794.1 identified by match to protein family HMM PF04286 YP_001746795.1 identified by match to protein family HMM PF07690 YP_001746796.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001746797.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_001746798.1 identified by match to protein family HMM PF06568 YP_001746799.1 identified by similarity to GB:CAH55816.1; match to protein family HMM PF03235; match to protein family HMM PF07510 YP_001746800.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_001746801.1 identified by similarity to GB:AAW87205.1 YP_001746802.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_001746803.1 identified by match to protein family HMM PF04328 YP_001746804.1 identified by match to protein family HMM PF02554 YP_001746805.1 identified by similarity to GB:AAD56429.1 YP_001746806.1 identified by similarity to SP:P72349; match to protein family HMM PF07908; match to protein family HMM PF07969 YP_001746807.1 yfgF; identified by match to protein family HMM PF01042 YP_001746808.1 identified by match to protein family HMM PF00474 YP_001746809.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001746810.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001746811.1 identified by match to protein family HMM PF07690 YP_001746812.1 identified by match to protein family HMM PF07729 YP_001746813.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001746814.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_001746816.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_001746817.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_001746819.1 identified by match to protein family HMM PF06738 YP_001746820.1 identified by Glimmer3; putative YP_001746821.1 identified by match to protein family HMM PF00196 YP_001746822.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_001746823.1 identified by match to protein family HMM PF06276 YP_001746824.1 identified by match to protein family HMM PF07256 YP_001746825.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001746826.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001746827.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001746828.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001746829.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001746830.1 identified by match to protein family HMM PF04972 YP_001746831.1 identified by Glimmer3; putative YP_001746832.1 identified by match to protein family HMM PF01734 YP_001746833.1 identified by match to protein family HMM PF01026 YP_001746834.1 identified by match to protein family HMM PF04055 YP_001746837.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001746838.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001746839.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001746840.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001746842.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_001746844.1 catalyzes the formation of serine from O-phosphoserine YP_001746845.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001746846.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001746848.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001746849.1 identified by Glimmer3; putative YP_001746850.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001746851.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001746852.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001746853.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001746854.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_001746855.1 identified by match to protein family HMM PF05981 YP_001746856.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001746857.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001746858.1 identified by match to protein family HMM PF06123 YP_001746859.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001746860.1 member of the SPOUT superfamily of methyltransferases