-- dump date 20140619_085715 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 444450000001 SEQ_END SEQ_END NC_011350.1 94644 94644 DR NC_011350.1; contig end 94644..94644 Escherichia coli O157:H7 str. EC4115 444450000002 SEQ_END SEQ_END NC_011351.1 37452 37452 DR NC_011351.1; contig end 37452..37452 Escherichia coli O157:H7 str. EC4115 444450000003 SEQ_END SEQ_END NC_011353.1 5572075 5572075 DR NC_011353.1; contig end 5572075..5572075 Escherichia coli O157:H7 str. EC4115 YP_002268403.1 CDS ECH74115_B0017 NC_011350.1 196 711 D identified by match to protein family HMM PF02794; hemolysin-activating lysine-acyltransferase HlyC 196..711 Escherichia coli O157:H7 str. EC4115 6966490 YP_002268404.1 CDS ECH74115_B0018 NC_011350.1 713 3709 D identified by match to protein family HMM PF00353; match to protein family HMM PF02382; match to protein family HMM PF08339; RTX C- domain protein 713..3709 Escherichia coli O157:H7 str. EC4115 6966441 YP_002268405.1 CDS ECH74115_B0019 NC_011350.1 3759 5879 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846; type I secretion system ATPase family protein 3759..5879 Escherichia coli O157:H7 str. EC4115 6966448 YP_002268406.1 CDS ECH74115_B0020 NC_011350.1 5883 7322 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843; leukotoxin secretion protein D 5883..7322 Escherichia coli O157:H7 str. EC4115 6966412 YP_002268407.1 CDS ECH74115_B0023 NC_011350.1 7898 8095 R identified by glimmer; putative; hypothetical protein complement(7898..8095) Escherichia coli O157:H7 str. EC4115 6966385 YP_002268408.1 CDS ECH74115_B0024 NC_011350.1 8417 9157 D identified by match to protein family HMM PF00589; site-specific recombinase 8417..9157 Escherichia coli O157:H7 str. EC4115 6966417 YP_002268409.1 CDS ECH74115_B0025 NC_011350.1 9247 9366 D hypothetical protein 9247..9366 Escherichia coli O157:H7 str. EC4115 6966393 YP_002268410.1 CDS ECH74115_B0026 NC_011350.1 9442 10419 R identified by match to protein family HMM PF01051; initiator RepB protein complement(9442..10419) Escherichia coli O157:H7 str. EC4115 6966414 YP_002268411.1 CDS ECH74115_B0027 NC_011350.1 10412 10582 R identified by glimmer; putative; hypothetical protein complement(10412..10582) Escherichia coli O157:H7 str. EC4115 6966430 YP_002268412.1 CDS ECH74115_B0029 NC_011350.1 10719 10832 D hypothetical protein 10719..10832 Escherichia coli O157:H7 str. EC4115 6966401 YP_002268413.1 CDS ECH74115_B0028 NC_011350.1 10827 11027 R w0044 complement(10827..11027) Escherichia coli O157:H7 str. EC4115 6966403 YP_002268414.1 CDS ECH74115_B0030 NC_011350.1 11024 11644 R hypothetical protein complement(11024..11644) Escherichia coli O157:H7 str. EC4115 6966464 YP_002268415.1 CDS ECH74115_B0031 NC_011350.1 11641 12099 R hypothetical protein complement(11641..12099) Escherichia coli O157:H7 str. EC4115 6966384 YP_002268416.1 CDS ECH74115_B0032 NC_011350.1 12112 12606 D w0046 12112..12606 Escherichia coli O157:H7 str. EC4115 6966377 YP_002268417.1 CDS ccdA2 NC_011350.1 12783 13001 D identified by match to protein family HMM PF07362; plasmid maintenance protein CcdA 12783..13001 Escherichia coli O157:H7 str. EC4115 6966415 YP_002268418.1 CDS ECH74115_B0035 NC_011350.1 13055 13942 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(13055..13942) Escherichia coli O157:H7 str. EC4115 6966440 YP_002268419.1 CDS ECH74115_B0036 NC_011350.1 13942 14268 R overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA complement(13942..14268) Escherichia coli O157:H7 str. EC4115 6966451 YP_002268420.1 CDS ECH74115_B0037 NC_011350.1 14367 14621 D controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 14367..14621 Escherichia coli O157:H7 str. EC4115 6966431 YP_002268421.1 CDS ECH74115_B0038 NC_011350.1 14622 15428 D identified by match to protein family HMM PF00589; resolvase 14622..15428 Escherichia coli O157:H7 str. EC4115 6966397 YP_002268422.1 CDS ECH74115_B0039 NC_011350.1 15440 15562 D identified by glimmer; putative; hypothetical protein 15440..15562 Escherichia coli O157:H7 str. EC4115 6966461 YP_002268423.1 CDS ECH74115_B0040 NC_011350.1 15622 15741 D identified by glimmer; putative; hypothetical protein 15622..15741 Escherichia coli O157:H7 str. EC4115 6966437 YP_002268424.1 CDS ECH74115_B0041 NC_011350.1 16151 17038 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(16151..17038) Escherichia coli O157:H7 str. EC4115 6966450 YP_002268425.1 CDS ECH74115_B0042 NC_011350.1 17038 17364 R overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA complement(17038..17364) Escherichia coli O157:H7 str. EC4115 6966439 YP_002268426.1 CDS ECH74115_B0044 NC_011350.1 18675 18827 R identified by glimmer; putative; hypothetical protein complement(18675..18827) Escherichia coli O157:H7 str. EC4115 6966387 YP_002268427.1 CDS sopA NC_011350.1 18792 19949 D identified by match to protein family HMM PF00376; match to protein family HMM PF01656; plasmid-partitioning protein SopA 18792..19949 Escherichia coli O157:H7 str. EC4115 6966381 YP_002268428.1 CDS sopB NC_011350.1 19949 20920 D SopB; plasmid-partitioning protein 19949..20920 Escherichia coli O157:H7 str. EC4115 6966484 YP_002268429.1 CDS ECH74115_B0048 NC_011350.1 21615 22517 D identified by match to protein family HMM PF06924; hypothetical protein 21615..22517 Escherichia coli O157:H7 str. EC4115 6966486 YP_002268430.1 CDS ECH74115_B0047 NC_011350.1 22468 22689 R hypothetical protein complement(22468..22689) Escherichia coli O157:H7 str. EC4115 6966376 YP_002268431.1 CDS ECH74115_B0049 NC_011350.1 22670 22795 R hypothetical protein complement(22670..22795) Escherichia coli O157:H7 str. EC4115 6966383 YP_002268432.1 CDS ECH74115_B0050 NC_011350.1 22903 23586 D identified by match to protein family HMM PF01555; putative methylase 22903..23586 Escherichia coli O157:H7 str. EC4115 6966382 YP_002268433.1 CDS ECH74115_B0051 NC_011350.1 23587 23808 D hypothetical protein 23587..23808 Escherichia coli O157:H7 str. EC4115 6966411 YP_002268434.1 CDS ECH74115_B0052 NC_011350.1 23822 24256 D identified by match to protein family HMM PF07128; hypothetical protein 23822..24256 Escherichia coli O157:H7 str. EC4115 6966476 YP_002268435.1 CDS ECH74115_B0053 NC_011350.1 24302 25078 D hypothetical protein 24302..25078 Escherichia coli O157:H7 str. EC4115 6966400 YP_002268436.1 CDS ECH74115_B0054 NC_011350.1 25208 25501 R hypothetical protein complement(25208..25501) Escherichia coli O157:H7 str. EC4115 6966487 YP_002268437.1 CDS ECH74115_B0055 NC_011350.1 25496 25921 D identified by match to protein family HMM PF03230; antirestriction protein 25496..25921 Escherichia coli O157:H7 str. EC4115 6966386 YP_002268438.1 CDS ECH74115_B0056 NC_011350.1 25968 26390 D hypothetical protein 25968..26390 Escherichia coli O157:H7 str. EC4115 6966477 YP_002268439.1 CDS ECH74115_B0058 NC_011350.1 26387 26578 D hypothetical protein 26387..26578 Escherichia coli O157:H7 str. EC4115 6966447 YP_002268440.1 CDS ECH74115_B0059 NC_011350.1 27212 27340 D identified by glimmer; putative; hypothetical protein 27212..27340 Escherichia coli O157:H7 str. EC4115 6966443 YP_002268441.1 CDS ECH74115_B0060 NC_011350.1 27403 27552 R identified by glimmer; putative; hypothetical protein complement(27403..27552) Escherichia coli O157:H7 str. EC4115 6966481 YP_002268442.1 CDS ECH74115_B0061 NC_011350.1 27574 27804 D hypothetical protein 27574..27804 Escherichia coli O157:H7 str. EC4115 6966375 YP_002268443.1 CDS ECH74115_B0062 NC_011350.1 27856 29217 D identified by glimmer; putative; hypothetical protein 27856..29217 Escherichia coli O157:H7 str. EC4115 6966480 YP_002268444.1 CDS ECH74115_B0063 NC_011350.1 29264 29827 D identified by glimmer; putative; hypothetical protein 29264..29827 Escherichia coli O157:H7 str. EC4115 6966465 YP_002268445.1 CDS ECH74115_B0065 NC_011350.1 30495 30656 D identified by glimmer; putative; hypothetical protein 30495..30656 Escherichia coli O157:H7 str. EC4115 6966473 YP_002268446.1 CDS ECH74115_B0066 NC_011350.1 30682 31134 D identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein 30682..31134 Escherichia coli O157:H7 str. EC4115 6966399 YP_002268447.1 CDS ECH74115_B0067 NC_011350.1 31191 31424 D identified by match to protein family HMM PF06006; hypothetical protein 31191..31424 Escherichia coli O157:H7 str. EC4115 6966478 YP_002268448.1 CDS ECH74115_B0068 NC_011350.1 31490 33448 D identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; plasmid partition protein B 31490..33448 Escherichia coli O157:H7 str. EC4115 6966483 YP_002268449.1 CDS psiB NC_011350.1 33503 33937 D identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 33503..33937 Escherichia coli O157:H7 str. EC4115 6966462 YP_002268450.1 CDS ECH74115_B0070 NC_011350.1 33934 34695 D PsiA; plasmid SOS inhibition protein A 33934..34695 Escherichia coli O157:H7 str. EC4115 6966470 YP_002268451.1 CDS hok NC_011350.1 34927 35085 D identified by match to protein family HMM PF01848; small toxic polypeptide 34927..35085 Escherichia coli O157:H7 str. EC4115 6966395 YP_002268452.1 CDS ECH74115_B0072 NC_011350.1 35267 37240 D identified by glimmer; putative; hypothetical protein 35267..37240 Escherichia coli O157:H7 str. EC4115 6966456 YP_002268453.1 CDS ECH74115_B0075 NC_011350.1 38854 39264 D transposase 38854..39264 Escherichia coli O157:H7 str. EC4115 6966405 YP_002268454.1 CDS ECH74115_B0076 NC_011350.1 39533 49042 D identified by match to protein family HMM PF04488; match to protein family HMM TIGR01586; glycosyltransferase sugar-binding region containing DXD motif family protein 39533..49042 Escherichia coli O157:H7 str. EC4115 6966453 YP_002268455.1 CDS ECH74115_B0077 NC_011350.1 49333 49836 R identified by match to protein family HMM PF01527; match to protein family HMM PF01695; putative transposase family protein complement(49333..49836) Escherichia coli O157:H7 str. EC4115 6966428 YP_002268456.1 CDS ECH74115_B0079 NC_011350.1 49983 51281 D identified by match to protein family HMM PF07057; protein TraI 49983..51281 Escherichia coli O157:H7 str. EC4115 6966374 YP_002268457.1 CDS traX NC_011350.1 51301 52047 D identified by match to protein family HMM PF05857; match to protein family HMM TIGR02755; conjugal transfer pilus acetylation protein TraX 51301..52047 Escherichia coli O157:H7 str. EC4115 6966467 YP_002268458.1 CDS ECH74115_B0081 NC_011350.1 52106 52966 D identified by match to protein family HMM PF00561; hydrolase, alpha/beta fold family 52106..52966 Escherichia coli O157:H7 str. EC4115 6966420 YP_002268459.1 CDS finO NC_011350.1 52994 53629 D identified by match to protein family HMM PF05286; conjugal transfer fertility inhibition protein FinO 52994..53629 Escherichia coli O157:H7 str. EC4115 6966426 YP_002268460.1 CDS ECH74115_B0083 NC_011350.1 53762 53974 D hypothetical protein 53762..53974 Escherichia coli O157:H7 str. EC4115 6966410 YP_002268461.1 CDS ECH74115_B0084 NC_011350.1 54219 54680 D identified by match to protein family HMM PF00565; nuclease-like protein 54219..54680 Escherichia coli O157:H7 str. EC4115 6966404 YP_002268462.1 CDS ECH74115_B0085 NC_011350.1 54726 54935 D identified by match to protein family HMM PF05321; hypothetical protein 54726..54935 Escherichia coli O157:H7 str. EC4115 6966466 YP_002268463.1 CDS ECH74115_B0086 NC_011350.1 54973 55311 D w0003 54973..55311 Escherichia coli O157:H7 str. EC4115 6966460 YP_002268464.1 CDS ECH74115_B0087 NC_011350.1 55551 55805 D replication protein 55551..55805 Escherichia coli O157:H7 str. EC4115 6966435 YP_002268465.1 CDS repA NC_011350.1 56108 56965 D RepA; replication protein 56108..56965 Escherichia coli O157:H7 str. EC4115 6966489 YP_002268466.1 CDS ECH74115_B0090 NC_011350.1 57040 57159 R identified by glimmer; putative; hypothetical protein complement(57040..57159) Escherichia coli O157:H7 str. EC4115 6966373 YP_002268467.1 CDS ECH74115_B0091 NC_011350.1 57282 57434 R identified by glimmer; putative; hypothetical protein complement(57282..57434) Escherichia coli O157:H7 str. EC4115 6966446 YP_002268468.1 CDS ECH74115_B0092 NC_011350.1 57878 58162 D identified by match to protein family HMM PF01402; CopG family protein 57878..58162 Escherichia coli O157:H7 str. EC4115 6966398 YP_002268469.1 CDS ECH74115_B0093 NC_011350.1 58162 58437 D identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 58162..58437 Escherichia coli O157:H7 str. EC4115 6966390 YP_002268470.1 CDS ECH74115_B0094 NC_011350.1 58532 58738 D hypothetical protein 58532..58738 Escherichia coli O157:H7 str. EC4115 6966469 YP_002268471.1 CDS ECH74115_B0095 NC_011350.1 58823 59044 R hypothetical protein complement(58823..59044) Escherichia coli O157:H7 str. EC4115 6966482 YP_002268472.1 CDS ECH74115_B0096 NC_011350.1 59097 59831 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; ISSd1, transposase OrfB complement(59097..59831) Escherichia coli O157:H7 str. EC4115 6966407 YP_002268473.1 CDS ECH74115_B0097 NC_011350.1 59615 60124 R overlaps another CDS with the same product name; transposase complement(59615..60124) Escherichia coli O157:H7 str. EC4115 6966409 YP_002268474.1 CDS ECH74115_B0098 NC_011350.1 60079 60264 R IS91, Orf2 complement(60079..60264) Escherichia coli O157:H7 str. EC4115 6966371 YP_002268475.1 CDS katG NC_011350.1 60441 62651 D identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 60441..62651 Escherichia coli O157:H7 str. EC4115 6966455 YP_002268476.1 CDS ECH74115_B0100 NC_011350.1 62695 63084 D identified by match to protein family HMM PF07361; cytochrome b562 family protein 62695..63084 Escherichia coli O157:H7 str. EC4115 6966380 YP_002268477.1 CDS ECH74115_B0101 NC_011350.1 63090 63242 D overlaps another CDS with the same product name; transposase OrfA 63090..63242 Escherichia coli O157:H7 str. EC4115 6966454 YP_002268478.1 CDS ECH74115_B0102 NC_011350.1 63242 64129 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 63242..64129 Escherichia coli O157:H7 str. EC4115 6966452 YP_002268479.1 CDS ECH74115_B0103 NC_011350.1 64132 64272 R identified by glimmer; putative; hypothetical protein complement(64132..64272) Escherichia coli O157:H7 str. EC4115 6966408 YP_002268480.1 CDS ECH74115_B0104 NC_011350.1 64310 68212 D identified by match to protein family HMM PF02395; match to protein family HMM PF03797; match to protein family HMM TIGR01414; immunoglobulin A1 protease domain protein 64310..68212 Escherichia coli O157:H7 str. EC4115 6966457 YP_002268481.1 CDS ECH74115_B0105 NC_011350.1 68375 68515 R hypothetical protein complement(68375..68515) Escherichia coli O157:H7 str. EC4115 6966419 YP_002268482.1 CDS ECH74115_B0106 NC_011350.1 68677 68841 R identified by match to protein family HMM PF03811; IS1 transposase orfA complement(68677..68841) Escherichia coli O157:H7 str. EC4115 6966427 YP_002268483.1 CDS ECH74115_B0107 NC_011350.1 69249 69371 D TnpA protein 69249..69371 Escherichia coli O157:H7 str. EC4115 6966425 YP_002268484.1 CDS ECH74115_B0108 NC_011350.1 69544 69678 R identified by glimmer; putative; hypothetical protein complement(69544..69678) Escherichia coli O157:H7 str. EC4115 6966444 YP_002268485.1 CDS ECH74115_B0110 NC_011350.1 70032 70205 R identified by glimmer; putative; hypothetical protein complement(70032..70205) Escherichia coli O157:H7 str. EC4115 6966379 YP_002268486.1 CDS ECH74115_B0111 NC_011350.1 70391 71212 D identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 70391..71212 Escherichia coli O157:H7 str. EC4115 6966378 YP_002268487.1 CDS ECH74115_B0112 NC_011350.1 71215 72318 D identified by match to protein family HMM PF00534; UDP-sugar hydrolase 71215..72318 Escherichia coli O157:H7 str. EC4115 6966459 YP_002268488.1 CDS ECH74115_B0113 NC_011350.1 72408 74129 D identified by match to protein family HMM PF00884; hypothetical protein 72408..74129 Escherichia coli O157:H7 str. EC4115 6966433 YP_002268489.1 CDS msbB NC_011350.1 74170 75201 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 74170..75201 Escherichia coli O157:H7 str. EC4115 6966468 YP_002268490.1 CDS ECH74115_B0115 NC_011350.1 75250 75375 R identified by glimmer; putative; hypothetical protein complement(75250..75375) Escherichia coli O157:H7 str. EC4115 6966402 YP_002268491.1 CDS ECH74115_B0116 NC_011350.1 75548 75949 D identified by match to protein family HMM PF01527; IS66 family element, orf1 75548..75949 Escherichia coli O157:H7 str. EC4115 6966424 YP_002268492.1 CDS ECH74115_B0117 NC_011350.1 75946 76293 D identified by match to protein family HMM PF05717; IS66 family element, orf2 75946..76293 Escherichia coli O157:H7 str. EC4115 6966472 YP_002268493.1 CDS ECH74115_B0118 NC_011350.1 76343 77881 D identified by match to protein family HMM PF03050; IS66 family element, transposase 76343..77881 Escherichia coli O157:H7 str. EC4115 6966372 YP_002268494.1 CDS ECH74115_B0119 NC_011350.1 77972 78088 R transposase IS3/family protein complement(77972..78088) Escherichia coli O157:H7 str. EC4115 6966418 YP_002268495.1 CDS ECH74115_B0120 NC_011350.1 78157 78369 D identified by glimmer; putative; hypothetical protein 78157..78369 Escherichia coli O157:H7 str. EC4115 6966432 YP_002268496.1 CDS ECH74115_B0001 NC_011350.1 78551 81247 D hypothetical protein 78551..81247 Escherichia coli O157:H7 str. EC4115 6966416 YP_002268497.1 CDS gspC NC_011350.1 81334 82209 D identified by match to protein family HMM TIGR01713; general secretion pathway protein C 81334..82209 Escherichia coli O157:H7 str. EC4115 6966479 YP_002268498.1 CDS gspD NC_011350.1 82210 84177 D identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517; general secretion pathway protein D 82210..84177 Escherichia coli O157:H7 str. EC4115 6966391 YP_002268499.1 CDS gspE NC_011350.1 84177 85682 D identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533; general secretory pathway protein E 84177..85682 Escherichia coli O157:H7 str. EC4115 6966471 YP_002268500.1 CDS gspF NC_011350.1 85684 86907 D identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120; general secretion pathway protein F 85684..86907 Escherichia coli O157:H7 str. EC4115 6966458 YP_002268501.1 CDS gspG NC_011350.1 86938 87372 D identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532; general secretion pathway protein G 86938..87372 Escherichia coli O157:H7 str. EC4115 6966463 YP_002268502.1 CDS gspH NC_011350.1 87369 87923 D identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532; general secretion pathway protein H 87369..87923 Escherichia coli O157:H7 str. EC4115 6966423 YP_002268503.1 CDS gspI NC_011350.1 87920 88285 D identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532; general secretion pathway protein I 87920..88285 Escherichia coli O157:H7 str. EC4115 6966434 YP_002268504.1 CDS gspJ NC_011350.1 88282 88881 D identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532; general secretion pathway protein J 88282..88881 Escherichia coli O157:H7 str. EC4115 6966449 YP_002268505.1 CDS gspK NC_011350.1 88878 89855 D identified by match to protein family HMM PF03934; general secretion pathway protein K 88878..89855 Escherichia coli O157:H7 str. EC4115 6966413 YP_002268506.1 CDS gspL NC_011350.1 89927 91066 D identified by match to protein family HMM PF05134; match to protein family HMM TIGR01709; general secretion pathway protein L 89927..91066 Escherichia coli O157:H7 str. EC4115 6966438 YP_002268507.1 CDS ECH74115_B0012 NC_011350.1 91053 91565 D identified by match to protein family HMM PF04612; EtpM 91053..91565 Escherichia coli O157:H7 str. EC4115 6966392 YP_002268508.1 CDS ECH74115_B0013 NC_011350.1 91632 92456 D identified by match to protein family HMM PF01478; match to protein family HMM PF06750; Peptidase A24 N- domain protein 91632..92456 Escherichia coli O157:H7 str. EC4115 6966474 YP_002268509.1 CDS ECH74115_B0014 NC_011350.1 92551 92949 D identified by match to protein family HMM PF09691; match to protein family HMM TIGR01004; EptO 92551..92949 Escherichia coli O157:H7 str. EC4115 6966429 YP_002268510.1 CDS ECH74115_B0015 NC_011350.1 93128 93433 D identified by match to protein family HMM PF01527; IS911, transposase orfA 93128..93433 Escherichia coli O157:H7 str. EC4115 6966389 YP_002268511.1 CDS ECH74115_A0001 NC_011351.1 93 1103 D identified by match to protein family HMM PF01051; plasmid replication protein 93..1103 Escherichia coli O157:H7 str. EC4115 6966546 YP_002268512.1 CDS ECH74115_A0002 NC_011351.1 1226 1495 D hypothetical protein 1226..1495 Escherichia coli O157:H7 str. EC4115 6966505 YP_002268513.1 CDS ECH74115_A0003 NC_011351.1 1624 1785 D identified by glimmer; putative; hypothetical protein 1624..1785 Escherichia coli O157:H7 str. EC4115 6966500 YP_002268514.1 CDS ECH74115_A0004 NC_011351.1 1757 2029 D hypothetical protein 1757..2029 Escherichia coli O157:H7 str. EC4115 6966532 YP_002268515.1 CDS ECH74115_A0005 NC_011351.1 2203 2439 D identified by glimmer; putative; hypothetical protein 2203..2439 Escherichia coli O157:H7 str. EC4115 6966536 YP_002268516.1 CDS ECH74115_A0006 NC_011351.1 2450 3451 D identified by match to protein family HMM PF04610; conjugal transfer protein 2450..3451 Escherichia coli O157:H7 str. EC4115 6966540 YP_002268517.1 CDS ECH74115_A0007 NC_011351.1 3453 3677 D hypothetical protein 3453..3677 Escherichia coli O157:H7 str. EC4115 6966539 YP_002268518.1 CDS ECH74115_A0008 NC_011351.1 3677 4318 D conjugal transfer protein TrbJ 3677..4318 Escherichia coli O157:H7 str. EC4115 6966517 YP_002268519.1 CDS ECH74115_A0009 NC_011351.1 4386 4997 D conjugal transfer protein 4386..4997 Escherichia coli O157:H7 str. EC4115 6966520 YP_002268520.1 CDS ECH74115_A0010 NC_011351.1 4990 5283 D conjugal transfer prepropilin 4990..5283 Escherichia coli O157:H7 str. EC4115 6966538 YP_002268521.1 CDS ECH74115_A0011 NC_011351.1 5311 5661 D identified by match to protein family HMM PF05101; conjugal transfer protein TraD 5311..5661 Escherichia coli O157:H7 str. EC4115 6966509 YP_002268522.1 CDS ECH74115_A0012 NC_011351.1 5658 8036 D identified by match to protein family HMM PF03135; conjugal transfer protein 5658..8036 Escherichia coli O157:H7 str. EC4115 6966496 YP_002268523.1 CDS ECH74115_A0013 NC_011351.1 8167 8904 D identified by match to protein family HMM PF04335; conjugal transfer protein TraG 8167..8904 Escherichia coli O157:H7 str. EC4115 6966502 YP_002268524.1 CDS ECH74115_A0014 NC_011351.1 8901 9680 D identified by match to protein family HMM PF03524; conjugal transfer outer membrane protein TraH 8901..9680 Escherichia coli O157:H7 str. EC4115 6966533 YP_002268525.1 CDS ECH74115_A0015 NC_011351.1 9670 10812 D identified by match to protein family HMM PF03743; conjugal transfer protein TraI 9670..10812 Escherichia coli O157:H7 str. EC4115 6966525 YP_002268526.1 CDS virB NC_011351.1 10812 11831 D identified by match to protein family HMM PF00437; match to protein family HMM TIGR02788; P-type DNA transfer ATPase VirB11 10812..11831 Escherichia coli O157:H7 str. EC4115 6966511 YP_002268527.1 CDS ECH74115_A0017 NC_011351.1 11883 13850 D identified by match to protein family HMM PF02534; conjugal transfer protein TraK 11883..13850 Escherichia coli O157:H7 str. EC4115 6966518 YP_002268528.1 CDS ECH74115_A0018 NC_011351.1 13866 14171 D TrbM-domain protein 13866..14171 Escherichia coli O157:H7 str. EC4115 6966495 YP_002268529.1 CDS ECH74115_A0019 NC_011351.1 14272 15894 D repeated sequence found in lipoprotein LPP 14272..15894 Escherichia coli O157:H7 str. EC4115 6966510 YP_002268530.1 CDS ECH74115_A0020 NC_011351.1 15924 16151 D identified by glimmer; putative; hypothetical protein 15924..16151 Escherichia coli O157:H7 str. EC4115 6966499 YP_002268531.1 CDS ECH74115_A0021 NC_011351.1 16276 16863 D hypothetical protein 16276..16863 Escherichia coli O157:H7 str. EC4115 6966519 YP_002268532.1 CDS topB NC_011351.1 16875 19031 D identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056; DNA topoisomerase III 16875..19031 Escherichia coli O157:H7 str. EC4115 6966544 YP_002268533.1 CDS ECH74115_A0023 NC_011351.1 19194 19379 D identified by glimmer; putative; hypothetical protein 19194..19379 Escherichia coli O157:H7 str. EC4115 6966497 YP_002268534.1 CDS ECH74115_A0024 NC_011351.1 19711 20007 D identified by glimmer; putative; hypothetical protein 19711..20007 Escherichia coli O157:H7 str. EC4115 6966541 YP_002268535.1 CDS ECH74115_A0026 NC_011351.1 21718 21933 D putative integral membrane protein 21718..21933 Escherichia coli O157:H7 str. EC4115 6966493 YP_002268536.1 CDS ECH74115_A0028 NC_011351.1 21940 22278 D hypothetical protein 21940..22278 Escherichia coli O157:H7 str. EC4115 6966501 YP_002268537.1 CDS ECH74115_A0027 NC_011351.1 22258 22398 R identified by glimmer; putative; hypothetical protein complement(22258..22398) Escherichia coli O157:H7 str. EC4115 6966537 YP_002268538.1 CDS ECH74115_A0029 NC_011351.1 22878 22991 R identified by glimmer; putative; hypothetical protein complement(22878..22991) Escherichia coli O157:H7 str. EC4115 6966529 YP_002268539.1 CDS ECH74115_A0030 NC_011351.1 22958 23140 R identified by glimmer; putative; hypothetical protein complement(22958..23140) Escherichia coli O157:H7 str. EC4115 6966494 YP_002268540.1 CDS ECH74115_A0031 NC_011351.1 23185 24000 D identified by match to protein family HMM PF00589; resolvase 23185..24000 Escherichia coli O157:H7 str. EC4115 6966507 YP_002268541.1 CDS ECH74115_A0032 NC_011351.1 24116 24775 D putative plasmid partition protein A 24116..24775 Escherichia coli O157:H7 str. EC4115 6966504 YP_002268542.1 CDS ECH74115_A0033 NC_011351.1 24807 25436 D hypothetical protein 24807..25436 Escherichia coli O157:H7 str. EC4115 6966492 YP_002268543.1 CDS ECH74115_A0034 NC_011351.1 25480 25782 D identified by glimmer; putative; hypothetical protein 25480..25782 Escherichia coli O157:H7 str. EC4115 6966514 YP_002268544.1 CDS ECH74115_A0035 NC_011351.1 25818 26102 D identified by glimmer; putative; hypothetical protein 25818..26102 Escherichia coli O157:H7 str. EC4115 6966503 YP_002268545.1 CDS ECH74115_A0036 NC_011351.1 26112 26411 D identified by glimmer; putative; hypothetical protein 26112..26411 Escherichia coli O157:H7 str. EC4115 6966542 YP_002268546.1 CDS ECH74115_A0037 NC_011351.1 26460 29657 R identified by match to protein family HMM PF03432; relaxase complement(26460..29657) Escherichia coli O157:H7 str. EC4115 6966545 YP_002268547.1 CDS ECH74115_A0038 NC_011351.1 29654 29989 R identified by match to protein family HMM PF01402; relaxosome component complement(29654..29989) Escherichia coli O157:H7 str. EC4115 6966527 YP_002268548.1 CDS ECH74115_A0039 NC_011351.1 30335 30742 D identified by glimmer; putative; hypothetical protein 30335..30742 Escherichia coli O157:H7 str. EC4115 6966498 YP_002268549.1 CDS ECH74115_A0040 NC_011351.1 30752 31513 D protein TraL 30752..31513 Escherichia coli O157:H7 str. EC4115 6966515 YP_002268550.1 CDS ECH74115_A0041 NC_011351.1 31510 32214 D hypothetical protein 31510..32214 Escherichia coli O157:H7 str. EC4115 6966543 YP_002268551.1 CDS ECH74115_A0042 NC_011351.1 32243 32680 R identified by match to protein family HMM PF03681; hypothetical protein complement(32243..32680) Escherichia coli O157:H7 str. EC4115 6966506 YP_002268552.1 CDS ECH74115_A0043 NC_011351.1 32705 32887 R identified by match to protein family HMM PF07927; hypothetical protein complement(32705..32887) Escherichia coli O157:H7 str. EC4115 6966513 YP_002268553.1 CDS ECH74115_A0044 NC_011351.1 33110 33244 R identified by glimmer; putative; hypothetical protein complement(33110..33244) Escherichia coli O157:H7 str. EC4115 6966535 YP_002268554.1 CDS ECH74115_A0045 NC_011351.1 33318 33596 R CcgD protein complement(33318..33596) Escherichia coli O157:H7 str. EC4115 6966528 YP_002268555.1 CDS ECH74115_A0046 NC_011351.1 33654 33983 R hypothetical protein complement(33654..33983) Escherichia coli O157:H7 str. EC4115 6966512 YP_002268556.1 CDS ECH74115_A0047 NC_011351.1 34129 34275 D identified by glimmer; putative; hypothetical protein 34129..34275 Escherichia coli O157:H7 str. EC4115 6966508 YP_002268557.1 CDS ECH74115_A0048 NC_011351.1 34421 34678 R YajA protein complement(34421..34678) Escherichia coli O157:H7 str. EC4115 6966523 YP_002268558.1 CDS ECH74115_A0049 NC_011351.1 34653 34919 R hypothetical protein complement(34653..34919) Escherichia coli O157:H7 str. EC4115 6966524 YP_002268559.1 CDS ECH74115_A0050 NC_011351.1 34970 35266 R identified by glimmer; putative; hypothetical protein complement(34970..35266) Escherichia coli O157:H7 str. EC4115 6966526 YP_002268560.1 CDS ECH74115_A0051 NC_011351.1 35290 35514 R hypothetical protein complement(35290..35514) Escherichia coli O157:H7 str. EC4115 6966522 YP_002268561.1 CDS ECH74115_A0052 NC_011351.1 35555 35878 R hypothetical protein complement(35555..35878) Escherichia coli O157:H7 str. EC4115 6966521 YP_002268562.1 CDS ECH74115_A0053 NC_011351.1 36025 36171 D identified by glimmer; putative; hypothetical protein 36025..36171 Escherichia coli O157:H7 str. EC4115 6966530 YP_002268563.1 CDS ECH74115_A0054 NC_011351.1 36673 37026 D identified by glimmer; putative; hypothetical protein 36673..37026 Escherichia coli O157:H7 str. EC4115 6966516 YP_002268564.1 CDS ECH74115_A0055 NC_011351.1 37252 37443 D identified by glimmer; putative; hypothetical protein 37252..37443 Escherichia coli O157:H7 str. EC4115 6966534 YP_002268609.1 CDS ECH74115_0001 NC_011353.1 133 351 R identified by glimmer; hypothetical protein complement(133..351) Escherichia coli O157:H7 str. EC4115 6972340 YP_002268610.1 CDS thrA NC_011353.1 360 2816 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 360..2816 Escherichia coli O157:H7 str. EC4115 6967964 YP_002268611.1 CDS thrB NC_011353.1 2818 3750 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2818..3750 Escherichia coli O157:H7 str. EC4115 6969252 YP_002268612.1 CDS thrC NC_011353.1 3751 5037 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3751..5037 Escherichia coli O157:H7 str. EC4115 6966720 YP_002268613.1 CDS ECH74115_0006 NC_011353.1 5251 5547 D hypothetical protein 5251..5547 Escherichia coli O157:H7 str. EC4115 6967554 YP_002268614.1 CDS ECH74115_0007 NC_011353.1 5700 6476 R identified by match to protein family HMM PF03883; hypothetical protein complement(5700..6476) Escherichia coli O157:H7 str. EC4115 6971082 YP_002268615.1 CDS agcS NC_011353.1 6546 7976 R identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid carrier protein complement(6546..7976) Escherichia coli O157:H7 str. EC4115 6972052 YP_002268616.1 CDS tal2 NC_011353.1 8192 9208 D identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase B 8192..9208 Escherichia coli O157:H7 str. EC4115 6969816 YP_002268617.1 CDS mogA NC_011353.1 9323 9910 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9323..9910 Escherichia coli O157:H7 str. EC4115 6970684 YP_002268618.1 CDS ECH74115_0011 NC_011353.1 9945 10511 R identified by match to protein family HMM PF01184; hypothetical protein complement(9945..10511) Escherichia coli O157:H7 str. EC4115 6969962 YP_002268619.1 CDS ECH74115_0012 NC_011353.1 10660 11373 R identified by match to protein family HMM PF03667; hypothetical protein complement(10660..11373) Escherichia coli O157:H7 str. EC4115 6970755 YP_002268620.1 CDS ECH74115_0013 NC_011353.1 11399 11803 R hypothetical protein complement(11399..11803) Escherichia coli O157:H7 str. EC4115 6967392 YP_002268621.1 CDS dnaK NC_011353.1 12180 14096 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12180..14096 Escherichia coli O157:H7 str. EC4115 6968061 YP_002268622.1 CDS dnaJ NC_011353.1 14185 15315 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 14185..15315 Escherichia coli O157:H7 str. EC4115 6970714 YP_002268623.1 CDS ECH74115_0016 NC_011353.1 15419 15571 R identified by match to protein family HMM PF01848; Hok/gef family protein complement(15419..15571) Escherichia coli O157:H7 str. EC4115 6970783 YP_002268624.1 CDS nhaA NC_011353.1 16157 17323 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 16157..17323 Escherichia coli O157:H7 str. EC4115 6967989 YP_002268625.1 CDS nhaR NC_011353.1 17383 18288 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 17383..18288 Escherichia coli O157:H7 str. EC4115 6968813 YP_002268626.1 CDS ECH74115_0019 NC_011353.1 18326 18853 R hypothetical protein complement(18326..18853) Escherichia coli O157:H7 str. EC4115 6966740 YP_002268627.1 CDS ECH74115_0023 NC_011353.1 21762 22445 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone complement(21762..22445) Escherichia coli O157:H7 str. EC4115 6970614 YP_002268628.1 CDS ECH74115_0024 NC_011353.1 22495 23028 R identified by match to protein family HMM PF00419; fimbrial protein complement(22495..23028) Escherichia coli O157:H7 str. EC4115 6968355 YP_002268629.1 CDS ECH74115_0025 NC_011353.1 23330 24751 R identified by glimmer; hypothetical protein complement(23330..24751) Escherichia coli O157:H7 str. EC4115 6967125 YP_002268630.1 CDS rpsT NC_011353.1 25221 25484 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(25221..25484) Escherichia coli O157:H7 str. EC4115 6969042 YP_002268631.1 CDS ribF NC_011353.1 25819 26760 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 25819..26760 Escherichia coli O157:H7 str. EC4115 6970880 YP_002268632.1 CDS ileS NC_011353.1 26803 29619 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 26803..29619 Escherichia coli O157:H7 str. EC4115 6967877 YP_002268633.1 CDS lspA NC_011353.1 29619 30113 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 29619..30113 Escherichia coli O157:H7 str. EC4115 6971635 YP_002268634.1 CDS fkpB NC_011353.1 30201 30650 D identified by match to protein family HMM PF00254; FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase 30201..30650 Escherichia coli O157:H7 str. EC4115 6970837 YP_002268635.1 CDS ispH NC_011353.1 30652 31602 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30652..31602 Escherichia coli O157:H7 str. EC4115 6970368 YP_002268636.1 CDS rihC NC_011353.1 31668 32582 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 31668..32582 Escherichia coli O157:H7 str. EC4115 6969711 YP_002268637.1 CDS dapB NC_011353.1 32749 33570 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 32749..33570 Escherichia coli O157:H7 str. EC4115 6971544 YP_002268638.1 CDS ECH74115_0034 NC_011353.1 33849 33986 D identified by glimmer; hypothetical protein 33849..33986 Escherichia coli O157:H7 str. EC4115 6970968 YP_002268639.1 CDS carA NC_011353.1 34026 35174 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 34026..35174 Escherichia coli O157:H7 str. EC4115 6971884 YP_002268640.1 CDS carB NC_011353.1 35192 38413 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 35192..38413 Escherichia coli O157:H7 str. EC4115 6971051 YP_002268641.1 CDS ECH74115_0037 NC_011353.1 38421 38639 R identified by glimmer; hypothetical protein complement(38421..38639) Escherichia coli O157:H7 str. EC4115 6967625 YP_002268642.1 CDS caiF NC_011353.1 38674 39069 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 38674..39069 Escherichia coli O157:H7 str. EC4115 6967002 YP_002268643.1 CDS paaY NC_011353.1 39188 39778 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(39188..39778) Escherichia coli O157:H7 str. EC4115 6971001 YP_002268644.1 CDS caiD NC_011353.1 39784 40677 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(39784..40677) Escherichia coli O157:H7 str. EC4115 6967307 YP_002268645.1 CDS caiC NC_011353.1 40678 42231 R identified by match to protein family HMM PF00501; crotonobetaine/carnitine-CoA ligase complement(40678..42231) Escherichia coli O157:H7 str. EC4115 6969473 YP_002268646.1 CDS caiB NC_011353.1 42305 43522 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(42305..43522) Escherichia coli O157:H7 str. EC4115 6971682 YP_002268647.1 CDS caiA NC_011353.1 43651 44793 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(43651..44793) Escherichia coli O157:H7 str. EC4115 6968409 YP_002268648.1 CDS caiT NC_011353.1 44824 46338 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(44824..46338) Escherichia coli O157:H7 str. EC4115 6970666 YP_002268649.1 CDS fixA NC_011353.1 46749 47582 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 46749..47582 Escherichia coli O157:H7 str. EC4115 6970308 YP_002268650.1 CDS fixB NC_011353.1 47597 48538 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 47597..48538 Escherichia coli O157:H7 str. EC4115 6969734 YP_002268651.1 CDS fixC NC_011353.1 48589 49875 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 48589..49875 Escherichia coli O157:H7 str. EC4115 6971572 YP_002268652.1 CDS fixX NC_011353.1 49872 50159 D ferredoxin-like protein FixX 49872..50159 Escherichia coli O157:H7 str. EC4115 6970932 YP_002268653.1 CDS ECH74115_0049 NC_011353.1 50217 51548 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 50217..51548 Escherichia coli O157:H7 str. EC4115 6968532 YP_002268654.1 CDS kefF NC_011353.1 51656 52186 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 51656..52186 Escherichia coli O157:H7 str. EC4115 6969817 YP_002268655.1 CDS kefC NC_011353.1 52179 54041 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52179..54041 Escherichia coli O157:H7 str. EC4115 6972089 YP_002268656.1 CDS folA NC_011353.1 54122 54712 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 54122..54712 Escherichia coli O157:H7 str. EC4115 6970193 YP_002268657.1 CDS ECH74115_0053 NC_011353.1 54798 55031 D identified by match to protein family HMM PF07362; hypothetical protein 54798..55031 Escherichia coli O157:H7 str. EC4115 6966681 YP_002268658.1 CDS ECH74115_0055 NC_011353.1 55034 55348 D identified by match to protein family HMM PF01845; CcdB protein 55034..55348 Escherichia coli O157:H7 str. EC4115 6971784 YP_002268659.1 CDS apaH NC_011353.1 55345 56193 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(55345..56193) Escherichia coli O157:H7 str. EC4115 6970653 YP_002268660.1 CDS apaG NC_011353.1 56200 56577 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(56200..56577) Escherichia coli O157:H7 str. EC4115 6970096 YP_002268661.1 CDS ksgA NC_011353.1 56580 57401 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(56580..57401) Escherichia coli O157:H7 str. EC4115 6969362 YP_002268662.1 CDS pdxA NC_011353.1 57398 58387 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(57398..58387) Escherichia coli O157:H7 str. EC4115 6968349 YP_002268663.1 CDS surA NC_011353.1 58387 59673 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(58387..59673) Escherichia coli O157:H7 str. EC4115 6970151 YP_002268664.1 CDS imp NC_011353.1 59726 62047 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(59726..62047) Escherichia coli O157:H7 str. EC4115 6969484 YP_002268665.1 CDS djlA NC_011353.1 62335 63150 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 62335..63150 Escherichia coli O157:H7 str. EC4115 6969597 YP_002268666.1 CDS ECH74115_0063 NC_011353.1 64600 65259 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(64600..65259) Escherichia coli O157:H7 str. EC4115 6967676 YP_002268667.1 CDS rapA NC_011353.1 65271 68030 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(65271..68030) Escherichia coli O157:H7 str. EC4115 6966907 YP_002268668.1 CDS polB NC_011353.1 68341 70692 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(68341..70692) Escherichia coli O157:H7 str. EC4115 6968583 YP_002268669.1 CDS araD NC_011353.1 70767 71462 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(70767..71462) Escherichia coli O157:H7 str. EC4115 6969180 YP_002268670.1 CDS araA NC_011353.1 71662 73164 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(71662..73164) Escherichia coli O157:H7 str. EC4115 6967375 YP_002268671.1 CDS araB NC_011353.1 73175 74875 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(73175..74875) Escherichia coli O157:H7 str. EC4115 6967927 YP_002268672.1 CDS araC NC_011353.1 75163 76092 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 75163..76092 Escherichia coli O157:H7 str. EC4115 6971804 YP_002268673.1 CDS ECH74115_0070 NC_011353.1 76178 76942 D identified by match to protein family HMM PF09335; hypothetical protein 76178..76942 Escherichia coli O157:H7 str. EC4115 6966581 YP_002268674.1 CDS thiQ NC_011353.1 77029 77727 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(77029..77727) Escherichia coli O157:H7 str. EC4115 6970633 YP_002268675.1 CDS thiP NC_011353.1 77711 79321 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(77711..79321) Escherichia coli O157:H7 str. EC4115 6970863 YP_002268676.1 CDS tbpA NC_011353.1 79297 80280 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(79297..80280) Escherichia coli O157:H7 str. EC4115 6969330 YP_002268677.1 CDS ECH74115_0075 NC_011353.1 80748 81221 D hypothetical protein 80748..81221 Escherichia coli O157:H7 str. EC4115 6970132 YP_002268678.1 CDS sgrR NC_011353.1 81450 83108 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(81450..83108) Escherichia coli O157:H7 str. EC4115 6969269 YP_002268679.1 CDS leuD NC_011353.1 83436 84041 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(83436..84041) Escherichia coli O157:H7 str. EC4115 6972252 YP_002268680.1 CDS leuC NC_011353.1 84052 85452 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(84052..85452) Escherichia coli O157:H7 str. EC4115 6968726 YP_002268681.1 CDS leuB NC_011353.1 85455 86546 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(85455..86546) Escherichia coli O157:H7 str. EC4115 6968264 YP_002268682.1 CDS leuA NC_011353.1 86546 88117 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(86546..88117) Escherichia coli O157:H7 str. EC4115 6970749 YP_002268683.1 CDS ECH74115_0083 NC_011353.1 88755 88877 D hypothetical protein 88755..88877 Escherichia coli O157:H7 str. EC4115 6969554 YP_002268684.1 CDS leuO NC_011353.1 88954 89898 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 88954..89898 Escherichia coli O157:H7 str. EC4115 6971485 YP_002268685.1 CDS ECH74115_0085 NC_011353.1 89934 90056 R identified by glimmer; hypothetical protein complement(89934..90056) Escherichia coli O157:H7 str. EC4115 6967651 YP_002268686.1 CDS ilvI NC_011353.1 90216 91940 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 90216..91940 Escherichia coli O157:H7 str. EC4115 6967348 YP_002268687.1 CDS ilvH NC_011353.1 91913 92434 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 91913..92434 Escherichia coli O157:H7 str. EC4115 6969236 YP_002268688.1 CDS fruR NC_011353.1 92614 93618 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 92614..93618 Escherichia coli O157:H7 str. EC4115 6970532 YP_002268689.1 CDS mraZ NC_011353.1 94220 94678 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 94220..94678 Escherichia coli O157:H7 str. EC4115 6970401 YP_002268690.1 CDS mraW NC_011353.1 94680 95621 D identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 94680..95621 Escherichia coli O157:H7 str. EC4115 6970989 YP_002268691.1 CDS ftsL NC_011353.1 95618 95983 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 95618..95983 Escherichia coli O157:H7 str. EC4115 6971604 YP_002268692.1 CDS ftsI NC_011353.1 95999 97765 D identified by match to protein family HMM PF00905; match to protein family HMM PF03717; peptidoglycan synthetase FtsI 95999..97765 Escherichia coli O157:H7 str. EC4115 6967284 YP_002268693.1 CDS murE NC_011353.1 97752 99239 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 97752..99239 Escherichia coli O157:H7 str. EC4115 6968654 YP_002268694.1 CDS murF NC_011353.1 99236 100594 D identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 99236..100594 Escherichia coli O157:H7 str. EC4115 6969213 YP_002268695.1 CDS mraY NC_011353.1 100588 101670 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 100588..101670 Escherichia coli O157:H7 str. EC4115 6969857 YP_002268696.1 CDS murD NC_011353.1 101673 102989 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 101673..102989 Escherichia coli O157:H7 str. EC4115 6969094 YP_002268697.1 CDS ftsW NC_011353.1 102989 104233 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 102989..104233 Escherichia coli O157:H7 str. EC4115 6969943 YP_002268698.1 CDS murG NC_011353.1 104230 105297 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 104230..105297 Escherichia coli O157:H7 str. EC4115 6969107 YP_002268699.1 CDS murC NC_011353.1 105351 106826 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 105351..106826 Escherichia coli O157:H7 str. EC4115 6968479 YP_002268700.1 CDS ddl NC_011353.1 106819 107739 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 106819..107739 Escherichia coli O157:H7 str. EC4115 6971829 YP_002268701.1 CDS ftsQ NC_011353.1 107741 108571 D involved in septum formation; cell division protein FtsQ 107741..108571 Escherichia coli O157:H7 str. EC4115 6971012 YP_002268702.1 CDS ftsA NC_011353.1 108568 109830 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 108568..109830 Escherichia coli O157:H7 str. EC4115 6971271 YP_002268703.1 CDS ftsZ NC_011353.1 109891 111042 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 109891..111042 Escherichia coli O157:H7 str. EC4115 6967776 YP_002268704.1 CDS lpxC NC_011353.1 111143 112060 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 111143..112060 Escherichia coli O157:H7 str. EC4115 6967167 YP_002268705.1 CDS secM NC_011353.1 112216 112803 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112216..112803 Escherichia coli O157:H7 str. EC4115 6968737 YP_002268706.1 CDS secA NC_011353.1 112865 115570 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 112865..115570 Escherichia coli O157:H7 str. EC4115 6968113 YP_002268707.1 CDS mutT NC_011353.1 115630 116028 D identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586; nucleoside triphosphate pyrophosphohydrolase 115630..116028 Escherichia coli O157:H7 str. EC4115 6970327 YP_002268708.1 CDS ECH74115_0108 NC_011353.1 116119 116316 R identified by match to protein family HMM PF03884; zinc-binding protein complement(116119..116316) Escherichia coli O157:H7 str. EC4115 6972138 YP_002268709.1 CDS ECH74115_0109 NC_011353.1 116326 117069 R identified by match to protein family HMM PF07072; hypothetical protein complement(116326..117069) Escherichia coli O157:H7 str. EC4115 6971470 YP_002268710.1 CDS coaE NC_011353.1 117069 117689 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(117069..117689) Escherichia coli O157:H7 str. EC4115 6970469 YP_002268711.1 CDS guaC NC_011353.1 117914 118957 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 117914..118957 Escherichia coli O157:H7 str. EC4115 6970056 YP_002268712.1 CDS pilC NC_011353.1 118992 120194 R identified by match to protein family HMM PF00482; type IV pilin biogenesis protein complement(118992..120194) Escherichia coli O157:H7 str. EC4115 6968931 YP_002268713.1 CDS hofB NC_011353.1 120184 121569 R identified by match to protein family HMM PF00437; hypothetical protein complement(120184..121569) Escherichia coli O157:H7 str. EC4115 6968055 YP_002268714.1 CDS pilA NC_011353.1 121579 122019 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; major pilin subunit complement(121579..122019) Escherichia coli O157:H7 str. EC4115 6966938 YP_002268715.1 CDS nadC NC_011353.1 122222 123115 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(122222..123115) Escherichia coli O157:H7 str. EC4115 6966878 YP_002268716.1 CDS ampD NC_011353.1 123203 123754 D identified by match to protein family HMM PF01510; N-acetyl-anhydromuranmyl-L-alanine amidase 123203..123754 Escherichia coli O157:H7 str. EC4115 6969310 YP_002268717.1 CDS ampE NC_011353.1 123751 124605 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 123751..124605 Escherichia coli O157:H7 str. EC4115 6967256 YP_002268718.1 CDS aroP NC_011353.1 124648 126018 R identified by match to protein family HMM PF00324; aromatic amino acid transporter complement(124648..126018) Escherichia coli O157:H7 str. EC4115 6970126 YP_002268719.1 CDS pdhR NC_011353.1 126562 127326 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 126562..127326 Escherichia coli O157:H7 str. EC4115 6968042 YP_002268720.1 CDS ECH74115_0119 NC_011353.1 127323 127505 R identified by glimmer; hypothetical protein complement(127323..127505) Escherichia coli O157:H7 str. EC4115 6971194 YP_002268721.1 CDS aceE NC_011353.1 127487 130150 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 127487..130150 Escherichia coli O157:H7 str. EC4115 6971172 YP_002268722.1 CDS aceF NC_011353.1 130165 132057 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 130165..132057 Escherichia coli O157:H7 str. EC4115 6969546 YP_002268723.1 CDS lpdA NC_011353.1 132202 133689 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 132202..133689 Escherichia coli O157:H7 str. EC4115 6970367 YP_002268724.1 CDS ECH74115_0124 NC_011353.1 133760 135613 R hypothetical protein complement(133760..135613) Escherichia coli O157:H7 str. EC4115 6968493 YP_002268725.1 CDS acnB NC_011353.1 135815 138565 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 135815..138565 Escherichia coli O157:H7 str. EC4115 6969305 YP_002268726.1 CDS ECH74115_0126 NC_011353.1 138741 139103 D identified by match to protein family HMM PF06062; hypothetical protein 138741..139103 Escherichia coli O157:H7 str. EC4115 6966977 YP_002268727.1 CDS speD NC_011353.1 139141 139935 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(139141..139935) Escherichia coli O157:H7 str. EC4115 6967750 YP_002268728.1 CDS speE NC_011353.1 139951 140817 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(139951..140817) Escherichia coli O157:H7 str. EC4115 6968131 YP_002268729.1 CDS ECH74115_0129 NC_011353.1 140923 141270 R hypothetical protein complement(140923..141270) Escherichia coli O157:H7 str. EC4115 6966678 YP_002268730.1 CDS cueO NC_011353.1 141436 142986 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 141436..142986 Escherichia coli O157:H7 str. EC4115 6968717 YP_002268731.1 CDS ECH74115_0131 NC_011353.1 143027 143164 R enterobactin synthetase component D complement(143027..143164) Escherichia coli O157:H7 str. EC4115 6971134 YP_002268732.1 CDS gcd NC_011353.1 143188 145578 R identified by match to protein family HMM PF01011; match to protein family HMM TIGR03074; quinoprotein glucose dehydrogenase complement(143188..145578) Escherichia coli O157:H7 str. EC4115 6967745 YP_002268733.1 CDS hpt NC_011353.1 145784 146320 D identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 145784..146320 Escherichia coli O157:H7 str. EC4115 6972071 YP_002268734.1 CDS can NC_011353.1 146361 147023 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(146361..147023) Escherichia coli O157:H7 str. EC4115 6971449 YP_002268735.1 CDS ECH74115_0135 NC_011353.1 147132 148058 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 147132..148058 Escherichia coli O157:H7 str. EC4115 6970649 YP_002268736.1 CDS ECH74115_0136 NC_011353.1 148055 148825 D identified by match to protein family HMM PF01061; ABC transporter permease 148055..148825 Escherichia coli O157:H7 str. EC4115 6970202 YP_002268737.1 CDS ECH74115_0137 NC_011353.1 148930 149370 D identified by match to protein family HMM PF03610; PTS system transporter subunit IIA domain-containing protein 148930..149370 Escherichia coli O157:H7 str. EC4115 6967409 YP_002268738.1 CDS ECH74115_0138 NC_011353.1 149434 150663 D identified by match to protein family HMM PF01522; polysaccharide deacetylase domain-containing protein 149434..150663 Escherichia coli O157:H7 str. EC4115 6966770 YP_002268739.1 CDS panD NC_011353.1 150667 151047 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(150667..151047) Escherichia coli O157:H7 str. EC4115 6967085 YP_002268740.1 CDS ECH74115_0140 NC_011353.1 151015 151209 D identified by glimmer; hypothetical protein 151015..151209 Escherichia coli O157:H7 str. EC4115 6967863 YP_002268741.1 CDS ECH74115_0141 NC_011353.1 151321 152217 D identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 151321..152217 Escherichia coli O157:H7 str. EC4115 6968457 YP_002268742.1 CDS panC NC_011353.1 152516 153367 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(152516..153367) Escherichia coli O157:H7 str. EC4115 6969266 YP_002268743.1 CDS panB NC_011353.1 153379 154173 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(153379..154173) Escherichia coli O157:H7 str. EC4115 6969584 YP_002268744.1 CDS ECH74115_0144 NC_011353.1 154308 155417 R identified by match to protein family HMM PF00419; fimbrial protein complement(154308..155417) Escherichia coli O157:H7 str. EC4115 6970529 YP_002268745.1 CDS ECH74115_0145 NC_011353.1 155429 156019 R identified by match to protein family HMM PF00419; fimbrial protein complement(155429..156019) Escherichia coli O157:H7 str. EC4115 6967868 YP_002268746.1 CDS ECH74115_0146 NC_011353.1 156040 156645 R fimbrial protein complement(156040..156645) Escherichia coli O157:H7 str. EC4115 6967077 YP_002268747.1 CDS ECH74115_0147 NC_011353.1 156660 157064 R fimbrial protein complement(156660..157064) Escherichia coli O157:H7 str. EC4115 6966667 YP_002268748.1 CDS ECH74115_0148 NC_011353.1 157222 159822 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(157222..159822) Escherichia coli O157:H7 str. EC4115 6972218 YP_002268749.1 CDS ECH74115_0149 NC_011353.1 159864 160589 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein EcpD complement(159864..160589) Escherichia coli O157:H7 str. EC4115 6967151 YP_002268750.1 CDS ECH74115_0150 NC_011353.1 160676 161272 R identified by match to protein family HMM PF00419; fimbrial protein complement(160676..161272) Escherichia coli O157:H7 str. EC4115 6967832 YP_002268751.1 CDS folK NC_011353.1 161553 162035 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(161553..162035) Escherichia coli O157:H7 str. EC4115 6968404 YP_002268752.1 CDS pcnB NC_011353.1 162032 163396 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I complement(162032..163396) Escherichia coli O157:H7 str. EC4115 6969097 YP_002268753.1 CDS gluQ NC_011353.1 163489 164415 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(163489..164415) Escherichia coli O157:H7 str. EC4115 6969596 YP_002268754.1 CDS dksA NC_011353.1 164452 164907 R identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420; RNA polymerase-binding transcription factor complement(164452..164907) Escherichia coli O157:H7 str. EC4115 6970287 YP_002268755.1 CDS sfsA NC_011353.1 165085 165789 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(165085..165789) Escherichia coli O157:H7 str. EC4115 6971093 YP_002268756.1 CDS ligT NC_011353.1 165804 166334 R identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258; 2'-5' RNA ligase complement(165804..166334) Escherichia coli O157:H7 str. EC4115 6971525 YP_002268757.1 CDS hrpB NC_011353.1 166363 168837 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 166363..168837 Escherichia coli O157:H7 str. EC4115 6971532 YP_002268758.1 CDS mrcB NC_011353.1 169033 171567 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 169033..171567 Escherichia coli O157:H7 str. EC4115 6967469 YP_002268759.1 CDS fhuA NC_011353.1 171787 174030 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 171787..174030 Escherichia coli O157:H7 str. EC4115 6971919 YP_002268760.1 CDS fhuC NC_011353.1 174081 174878 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 174081..174878 Escherichia coli O157:H7 str. EC4115 6969839 YP_002268761.1 CDS fhuD NC_011353.1 174878 175768 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 174878..175768 Escherichia coli O157:H7 str. EC4115 6969568 YP_002268762.1 CDS fhuB NC_011353.1 175765 177747 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 175765..177747 Escherichia coli O157:H7 str. EC4115 6971945 YP_002268763.1 CDS hemL NC_011353.1 177782 179062 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(177782..179062) Escherichia coli O157:H7 str. EC4115 6967187 YP_002268764.1 CDS clcA NC_011353.1 179287 180708 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 179287..180708 Escherichia coli O157:H7 str. EC4115 6970694 YP_002268765.1 CDS yadR NC_011353.1 180790 181134 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 180790..181134 Escherichia coli O157:H7 str. EC4115 6970922 YP_002268766.1 CDS ECH74115_0167 NC_011353.1 181181 181804 R identified by match to protein family HMM PF03458; hypothetical protein complement(181181..181804) Escherichia coli O157:H7 str. EC4115 6969001 YP_002268767.1 CDS btuF NC_011353.1 181842 182642 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(181842..182642) Escherichia coli O157:H7 str. EC4115 6970453 YP_002268768.1 CDS mtnN NC_011353.1 182635 183333 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(182635..183333) Escherichia coli O157:H7 str. EC4115 6968792 YP_002268769.1 CDS dgt NC_011353.1 183417 184934 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 183417..184934 Escherichia coli O157:H7 str. EC4115 6967955 YP_002268770.1 CDS degP NC_011353.1 185064 186488 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 185064..186488 Escherichia coli O157:H7 str. EC4115 6967528 YP_002268771.1 CDS cdaR NC_011353.1 186643 187800 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 186643..187800 Escherichia coli O157:H7 str. EC4115 6966792 YP_002268772.1 CDS ECH74115_0173 NC_011353.1 187889 188275 R hypothetical protein complement(187889..188275) Escherichia coli O157:H7 str. EC4115 6967027 YP_002268773.1 CDS dapD NC_011353.1 188590 189414 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(188590..189414) Escherichia coli O157:H7 str. EC4115 6972191 YP_002268774.1 CDS glnD NC_011353.1 189445 192117 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(189445..192117) Escherichia coli O157:H7 str. EC4115 6971388 YP_002268775.1 CDS map NC_011353.1 192179 192973 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(192179..192973) Escherichia coli O157:H7 str. EC4115 6970688 YP_002268776.1 CDS rpsB NC_011353.1 193341 194066 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 193341..194066 Escherichia coli O157:H7 str. EC4115 6972285 YP_002268777.1 CDS ECH74115_0178 NC_011353.1 194018 194305 R hypothetical protein complement(194018..194305) Escherichia coli O157:H7 str. EC4115 6970476 YP_002268778.1 CDS tsf NC_011353.1 194324 195175 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 194324..195175 Escherichia coli O157:H7 str. EC4115 6971673 YP_002268779.1 CDS pyrH NC_011353.1 195322 196047 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 195322..196047 Escherichia coli O157:H7 str. EC4115 6970408 YP_002268780.1 CDS frr NC_011353.1 196197 196754 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 196197..196754 Escherichia coli O157:H7 str. EC4115 6968416 YP_002268781.1 CDS dxr NC_011353.1 196846 198042 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 196846..198042 Escherichia coli O157:H7 str. EC4115 6969049 YP_002268782.1 CDS uppS NC_011353.1 198228 198989 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 198228..198989 Escherichia coli O157:H7 str. EC4115 6966595 YP_002268783.1 CDS cdsA NC_011353.1 199002 199859 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 199002..199859 Escherichia coli O157:H7 str. EC4115 6967788 YP_002268784.1 CDS rseP NC_011353.1 199871 201223 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 199871..201223 Escherichia coli O157:H7 str. EC4115 6970590 YP_002268785.1 CDS yaeT NC_011353.1 201253 203685 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 201253..203685 Escherichia coli O157:H7 str. EC4115 6970224 YP_002268786.1 CDS skp NC_011353.1 203806 204291 D identified by match to protein family HMM PF03938; periplasmic chaperone 203806..204291 Escherichia coli O157:H7 str. EC4115 6972098 YP_002268787.1 CDS lpxD NC_011353.1 204295 205320 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 204295..205320 Escherichia coli O157:H7 str. EC4115 6968657 YP_002268788.1 CDS fabZ NC_011353.1 205425 205880 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 205425..205880 Escherichia coli O157:H7 str. EC4115 6969361 YP_002268789.1 CDS lpxA NC_011353.1 205884 206672 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 205884..206672 Escherichia coli O157:H7 str. EC4115 6967008 YP_002268790.1 CDS lpxB NC_011353.1 206672 207820 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 206672..207820 Escherichia coli O157:H7 str. EC4115 6967447 YP_002268791.1 CDS rnhB NC_011353.1 207817 208413 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 207817..208413 Escherichia coli O157:H7 str. EC4115 6971154 YP_002268792.1 CDS dnaE NC_011353.1 208450 211932 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 208450..211932 Escherichia coli O157:H7 str. EC4115 6971603 YP_002268793.1 CDS accA NC_011353.1 211945 212904 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 211945..212904 Escherichia coli O157:H7 str. EC4115 6969534 YP_002268794.1 CDS ldcC1 NC_011353.1 213003 215144 D identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase, constitutive 213003..215144 Escherichia coli O157:H7 str. EC4115 6969972 YP_002268795.1 CDS ECH74115_0197 NC_011353.1 215201 215590 D identified by match to protein family HMM PF00903; hypothetical protein 215201..215590 Escherichia coli O157:H7 str. EC4115 6972012 YP_002268796.1 CDS tilS NC_011353.1 215655 216950 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 215655..216950 Escherichia coli O157:H7 str. EC4115 6967656 YP_002268797.1 CDS rof NC_011353.1 217003 217263 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(217003..217263) Escherichia coli O157:H7 str. EC4115 6970854 YP_002268798.1 CDS ECH74115_0200 NC_011353.1 217250 217450 R identified by match to protein family HMM PF06786; hypothetical protein complement(217250..217450) Escherichia coli O157:H7 str. EC4115 6971680 YP_002268799.1 CDS ECH74115_0201 NC_011353.1 217616 218161 D identified by match to protein family HMM PF07152; hypothetical protein 217616..218161 Escherichia coli O157:H7 str. EC4115 6970247 YP_002268800.1 CDS ECH74115_0202 NC_011353.1 218158 218568 D identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein 218158..218568 Escherichia coli O157:H7 str. EC4115 6968160 YP_002268801.1 CDS cutF NC_011353.1 218582 219292 D identified by match to protein family HMM PF04170; copper homeostasis and adhesion lipoprotein 218582..219292 Escherichia coli O157:H7 str. EC4115 6968989 YP_002268802.1 CDS ECH74115_0204 NC_011353.1 219492 220316 R hypothetical protein complement(219492..220316) Escherichia coli O157:H7 str. EC4115 6969103 YP_002268803.1 CDS proS NC_011353.1 220369 222087 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(220369..222087) Escherichia coli O157:H7 str. EC4115 6970459 YP_002268804.1 CDS ECH74115_0206 NC_011353.1 222198 222905 R identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104; hypothetical protein complement(222198..222905) Escherichia coli O157:H7 str. EC4115 6969609 YP_002268805.1 CDS rcsF NC_011353.1 222902 223255 R outer membrane lipoprotein complement(222902..223255) Escherichia coli O157:H7 str. EC4115 6968375 YP_002268806.1 CDS metQ NC_011353.1 223424 224239 R identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; DL-methionine transporter substrate-binding subunit complement(223424..224239) Escherichia coli O157:H7 str. EC4115 6968655 YP_002268807.1 CDS metI NC_011353.1 224279 224932 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(224279..224932) Escherichia coli O157:H7 str. EC4115 6971667 YP_002268808.1 CDS metN NC_011353.1 224925 225956 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(224925..225956) Escherichia coli O157:H7 str. EC4115 6970876 YP_002268809.1 CDS ECH74115_0211 NC_011353.1 226144 226719 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 226144..226719 Escherichia coli O157:H7 str. EC4115 6970449 YP_002268810.1 CDS dkgB NC_011353.1 232479 233282 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 232479..233282 Escherichia coli O157:H7 str. EC4115 6972360 YP_002268811.1 CDS ECH74115_0219 NC_011353.1 233279 234193 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(233279..234193) Escherichia coli O157:H7 str. EC4115 6968593 YP_002268812.1 CDS ECH74115_0221 NC_011353.1 234434 235234 D identified by match to protein family HMM PF03372; hypothetical protein 234434..235234 Escherichia coli O157:H7 str. EC4115 6968851 YP_002268813.1 CDS ECH74115_0222 NC_011353.1 235312 236082 D identified by match to protein family HMM PF01209; match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; UbiE/COQ5 family methyltransferase 235312..236082 Escherichia coli O157:H7 str. EC4115 6967669 YP_002268814.1 CDS mltD NC_011353.1 236130 237350 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(236130..237350) Escherichia coli O157:H7 str. EC4115 6969108 YP_002268815.1 CDS gloB NC_011353.1 237560 238315 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(237560..238315) Escherichia coli O157:H7 str. EC4115 6968504 YP_002268816.1 CDS ECH74115_0226 NC_011353.1 238349 239071 D identified by match to protein family HMM PF08241; methyltransferase 238349..239071 Escherichia coli O157:H7 str. EC4115 6967679 YP_002268817.1 CDS rnhA NC_011353.1 239068 239535 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(239068..239535) Escherichia coli O157:H7 str. EC4115 6971707 YP_002268818.1 CDS dnaQ NC_011353.1 239600 240331 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 239600..240331 Escherichia coli O157:H7 str. EC4115 6967060 YP_002268819.1 CDS ECH74115_0229 NC_011353.1 240869 241669 D hypothetical protein 240869..241669 Escherichia coli O157:H7 str. EC4115 6972378 YP_002268820.1 CDS ECH74115_0230 NC_011353.1 241854 242003 R hypothetical protein complement(241854..242003) Escherichia coli O157:H7 str. EC4115 6970292 YP_002268821.1 CDS ECH74115_0233 NC_011353.1 243962 245371 R identified by match to protein family HMM PF06812; ImpA domain-containing protein complement(243962..245371) Escherichia coli O157:H7 str. EC4115 6968407 YP_002268822.1 CDS ECH74115_0235 NC_011353.1 248953 250365 R identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362; ImpA domain-containing protein complement(248953..250365) Escherichia coli O157:H7 str. EC4115 6970478 YP_002268823.1 CDS ECH74115_0236 NC_011353.1 250370 251113 R identified by match to protein family HMM TIGR03360; type VI secretion-associated protein complement(250370..251113) Escherichia coli O157:H7 str. EC4115 6970866 YP_002268824.1 CDS clpV NC_011353.1 251110 253881 R identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345; type VI secretion ATPase, ClpV1 family complement(251110..253881) Escherichia coli O157:H7 str. EC4115 6972231 YP_002268825.1 CDS ECH74115_0238 NC_011353.1 253890 254651 R identified by match to protein family HMM TIGR03349; hypothetical protein complement(253890..254651) Escherichia coli O157:H7 str. EC4115 6968883 YP_002268826.1 CDS ECH74115_0239 NC_011353.1 254656 255987 R identified by match to protein family HMM PF05936; match to protein family HMM TIGR03353; hypothetical protein complement(254656..255987) Escherichia coli O157:H7 str. EC4115 6966763 YP_002268827.1 CDS ECH74115_0240 NC_011353.1 255990 256514 R identified by match to protein family HMM TIGR03352; type VI secretion lipoprotein complement(255990..256514) Escherichia coli O157:H7 str. EC4115 6969827 YP_002268828.1 CDS ECH74115_0241 NC_011353.1 256511 257791 R identified by match to protein family HMM TIGR03354; hypothetical protein complement(256511..257791) Escherichia coli O157:H7 str. EC4115 6970626 YP_002268829.1 CDS ECH74115_0242 NC_011353.1 257816 258898 R identified by match to protein family HMM PF06996; match to protein family HMM TIGR03347; hypothetical protein complement(257816..258898) Escherichia coli O157:H7 str. EC4115 6972238 YP_002268830.1 CDS ECH74115_0243 NC_011353.1 258862 260712 R identified by match to protein family HMM PF05947; match to protein family HMM TIGR03359; hypothetical protein complement(258862..260712) Escherichia coli O157:H7 str. EC4115 6969966 YP_002268831.1 CDS ECH74115_0244 NC_011353.1 260716 261129 R identified by match to protein family HMM PF04965; match to protein family HMM TIGR03357; hypothetical protein complement(260716..261129) Escherichia coli O157:H7 str. EC4115 6967909 YP_002268832.1 CDS ECH74115_0246 NC_011353.1 262662 262886 R identified by glimmer; hypothetical protein complement(262662..262886) Escherichia coli O157:H7 str. EC4115 6971621 YP_002268833.1 CDS ECH74115_0247 NC_011353.1 262921 263421 R identified by match to protein family HMM PF05591; match to protein family HMM TIGR03358; hypothetical protein complement(262921..263421) Escherichia coli O157:H7 str. EC4115 6966569 YP_002268834.1 CDS ECH74115_0248 NC_011353.1 263848 263991 D identified by glimmer; hypothetical protein 263848..263991 Escherichia coli O157:H7 str. EC4115 6968003 YP_002268835.1 CDS ECH74115_0249 NC_011353.1 264118 264636 D identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 264118..264636 Escherichia coli O157:H7 str. EC4115 6968601 YP_002268836.1 CDS ECH74115_0250 NC_011353.1 264669 264806 D identified by glimmer; hypothetical protein 264669..264806 Escherichia coli O157:H7 str. EC4115 6969793 YP_002268837.1 CDS ECH74115_0251 NC_011353.1 264846 266987 D identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 264846..266987 Escherichia coli O157:H7 str. EC4115 6970642 YP_002268838.1 CDS ECH74115_0252 NC_011353.1 267063 271295 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 267063..271295 Escherichia coli O157:H7 str. EC4115 6970670 YP_002268839.1 CDS ECH74115_0253 NC_011353.1 271435 272151 D identified by match to protein family HMM PF00023; ankyrin repeat-containing domain-containing protein 271435..272151 Escherichia coli O157:H7 str. EC4115 6971466 YP_002268840.1 CDS ECH74115_0254 NC_011353.1 272333 273841 D identified by match to protein family HMM PF03527; RhsG core protein with extension 272333..273841 Escherichia coli O157:H7 str. EC4115 6972234 YP_002268841.1 CDS ECH74115_0255 NC_011353.1 273844 274467 D hypothetical protein 273844..274467 Escherichia coli O157:H7 str. EC4115 6970582 YP_002268842.1 CDS ECH74115_0256 NC_011353.1 274470 274616 R identified by glimmer; hypothetical protein complement(274470..274616) Escherichia coli O157:H7 str. EC4115 6968163 YP_002268843.1 CDS ECH74115_0257 NC_011353.1 275213 276349 D identified by match to protein family HMM PF01609; ISEc3, transposase 275213..276349 Escherichia coli O157:H7 str. EC4115 6968993 YP_002268844.1 CDS ECH74115_0258 NC_011353.1 276352 278112 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; RHS Repeat family protein 276352..278112 Escherichia coli O157:H7 str. EC4115 6967418 YP_002268845.1 CDS ECH74115_0261 NC_011353.1 278561 278710 D identified by glimmer; hypothetical protein 278561..278710 Escherichia coli O157:H7 str. EC4115 6970548 YP_002268846.1 CDS ECH74115_0262 NC_011353.1 278758 279930 D identified by match to protein family HMM PF01609; transposase, IS4 family 278758..279930 Escherichia coli O157:H7 str. EC4115 6970319 YP_002268847.1 CDS ECH74115_0263 NC_011353.1 280048 280818 R identified by match to protein family HMM PF00795; hypothetical protein complement(280048..280818) Escherichia coli O157:H7 str. EC4115 6968190 YP_002268848.1 CDS ECH74115_0264 NC_011353.1 280996 281445 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 280996..281445 Escherichia coli O157:H7 str. EC4115 6968835 YP_002268849.1 CDS fadE NC_011353.1 281488 283932 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(281488..283932) Escherichia coli O157:H7 str. EC4115 6966597 YP_002268850.1 CDS gmhA NC_011353.1 284172 284750 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 284172..284750 Escherichia coli O157:H7 str. EC4115 6968939 YP_002268851.1 CDS ECH74115_0268 NC_011353.1 284855 285622 D identified by match to protein family HMM PF00310; glutamine amidotransferase 284855..285622 Escherichia coli O157:H7 str. EC4115 6968197 YP_002268852.1 CDS ECH74115_0267 NC_011353.1 285593 286333 R identified by match to protein family HMM PF06104; hypothetical protein complement(285593..286333) Escherichia coli O157:H7 str. EC4115 6970949 YP_002268853.1 CDS dinJ NC_011353.1 286768 287028 R identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin component DinJ complement(286768..287028) Escherichia coli O157:H7 str. EC4115 6971412 YP_002268854.1 CDS ECH74115_0271 NC_011353.1 287214 287987 D identified by match to protein family HMM PF00877; NlpC/P60 family protein 287214..287987 Escherichia coli O157:H7 str. EC4115 6967906 YP_002268855.1 CDS ECH74115_0273 NC_011353.1 288678 288797 D identified by glimmer; hypothetical protein 288678..288797 Escherichia coli O157:H7 str. EC4115 6968093 YP_002268856.1 CDS ECH74115_0274 NC_011353.1 288805 290544 R identified by match to protein family HMM PF00771; type III secretion protein, FHIPEP family complement(288805..290544) Escherichia coli O157:H7 str. EC4115 6970072 YP_002268857.1 CDS ECH74115_0275 NC_011353.1 290504 291274 D identified by match to protein family HMM PF00691; hypothetical protein 290504..291274 Escherichia coli O157:H7 str. EC4115 6968033 YP_002268858.1 CDS dinB NC_011353.1 291345 292400 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 291345..292400 Escherichia coli O157:H7 str. EC4115 6968828 YP_002268859.1 CDS ECH74115_0277 NC_011353.1 292452 292745 D identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552; antitoxin of the YafO-YafN toxin-antitoxin system 292452..292745 Escherichia coli O157:H7 str. EC4115 6971138 YP_002268860.1 CDS ECH74115_0278 NC_011353.1 292748 293146 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 292748..293146 Escherichia coli O157:H7 str. EC4115 6971594 YP_002268861.1 CDS ECH74115_0279 NC_011353.1 293156 293608 D identified by match to protein family HMM PF00583; hypothetical protein 293156..293608 Escherichia coli O157:H7 str. EC4115 6969736 YP_002268862.1 CDS ECH74115_0280 NC_011353.1 293927 294181 D release factor H-coupled RctB family protein 293927..294181 Escherichia coli O157:H7 str. EC4115 6970369 YP_002268863.1 CDS prfH NC_011353.1 294150 294650 D similar to release factor 1 and 2; peptide chain release factor-like protein 294150..294650 Escherichia coli O157:H7 str. EC4115 6968458 YP_002268864.1 CDS pepD NC_011353.1 294707 296164 R identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase complement(294707..296164) Escherichia coli O157:H7 str. EC4115 6969322 YP_002268865.1 CDS gpt NC_011353.1 296425 296883 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 296425..296883 Escherichia coli O157:H7 str. EC4115 6967080 YP_002268866.1 CDS frsA NC_011353.1 296975 298219 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 296975..298219 Escherichia coli O157:H7 str. EC4115 6968739 YP_002268867.1 CDS crl NC_011353.1 298277 298678 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 298277..298678 Escherichia coli O157:H7 str. EC4115 6972117 YP_002268868.1 CDS phoE NC_011353.1 298717 299772 R identified by match to protein family HMM PF00267; outer membrane phosphoporin protein E complement(298717..299772) Escherichia coli O157:H7 str. EC4115 6971197 YP_002268869.1 CDS proB NC_011353.1 300060 301163 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 300060..301163 Escherichia coli O157:H7 str. EC4115 6970410 YP_002268870.1 CDS proA NC_011353.1 301175 302428 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 301175..302428 Escherichia coli O157:H7 str. EC4115 6969590 YP_002268871.1 CDS ECH74115_0290 NC_011353.1 302633 303607 R identified by match to protein family HMM PF00589; integrase complement(302633..303607) Escherichia coli O157:H7 str. EC4115 6972368 YP_002268872.1 CDS ECH74115_0291 NC_011353.1 304070 304960 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(304070..304960) Escherichia coli O157:H7 str. EC4115 6968010 YP_002268873.1 CDS ECH74115_0292 NC_011353.1 304957 305283 R overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA complement(304957..305283) Escherichia coli O157:H7 str. EC4115 6968522 YP_002268874.1 CDS ECH74115_0293 NC_011353.1 305820 306533 R identified by match to protein family HMM PF00717; match to protein family HMM PF01381; prophage repressor complement(305820..306533) Escherichia coli O157:H7 str. EC4115 6967713 YP_002268875.1 CDS ECH74115_0294 NC_011353.1 306634 306834 D identified by match to protein family HMM PF09048; hypothetical protein 306634..306834 Escherichia coli O157:H7 str. EC4115 6966914 YP_002268876.1 CDS ECH74115_0295 NC_011353.1 307109 307246 D identified by match to protein family HMM PF05269; regulatory protein CII 307109..307246 Escherichia coli O157:H7 str. EC4115 6968740 YP_002268877.1 CDS ECH74115_0297 NC_011353.1 308198 308509 D replication protein P for prophage CP-933H 308198..308509 Escherichia coli O157:H7 str. EC4115 6967691 YP_002268878.1 CDS ECH74115_0298 NC_011353.1 308509 309303 D identified by match to protein family HMM PF07484; tail fiber protein 308509..309303 Escherichia coli O157:H7 str. EC4115 6971509 YP_002268879.1 CDS ECH74115_0300 NC_011353.1 309303 309896 D identified by match to protein family HMM PF02413; tail fiber assembly protein-like protein 309303..309896 Escherichia coli O157:H7 str. EC4115 6971028 YP_002268880.1 CDS ECH74115_0299 NC_011353.1 309868 310311 R identified by match to protein family HMM PF02413; tail fiber assembly protein complement(309868..310311) Escherichia coli O157:H7 str. EC4115 6969547 YP_002268881.1 CDS ECH74115_0301 NC_011353.1 310332 310742 R tail fiber protein complement(310332..310742) Escherichia coli O157:H7 str. EC4115 6969879 YP_002268882.1 CDS ECH74115_0302 NC_011353.1 310772 311326 D identified by match to protein family HMM PF00239; match to protein family HMM PF02796; DNA-invertase 310772..311326 Escherichia coli O157:H7 str. EC4115 6970348 YP_002268883.1 CDS ECH74115_0303 NC_011353.1 311384 312157 R hypothetical protein complement(311384..312157) Escherichia coli O157:H7 str. EC4115 6968526 YP_002268884.1 CDS ECH74115_0304 NC_011353.1 312981 313724 D identified by match to protein family HMM PF00165; transcriptional regulator 312981..313724 Escherichia coli O157:H7 str. EC4115 6969299 YP_002268885.1 CDS ECH74115_0305 NC_011353.1 313766 314131 R IS2 ORF2 complement(313766..314131) Escherichia coli O157:H7 str. EC4115 6970565 YP_002268886.1 CDS ECH74115_0306 NC_011353.1 314636 315868 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 314636..315868 Escherichia coli O157:H7 str. EC4115 6968335 YP_002268887.1 CDS ECH74115_0308 NC_011353.1 317220 317336 D hypothetical protein 317220..317336 Escherichia coli O157:H7 str. EC4115 6969165 YP_002268888.1 CDS ECH74115_0312 NC_011353.1 318581 319147 D hypothetical protein 318581..319147 Escherichia coli O157:H7 str. EC4115 6971541 YP_002268889.1 CDS ECH74115_0313 NC_011353.1 319557 319679 R Ogr family transcription activator complement(319557..319679) Escherichia coli O157:H7 str. EC4115 6969691 YP_002268890.1 CDS ECH74115_0314 NC_011353.1 319835 320386 R identified by match to protein family HMM PF07455; polarity suppression protein complement(319835..320386) Escherichia coli O157:H7 str. EC4115 6970286 YP_002268891.1 CDS ECH74115_0315 NC_011353.1 320383 321135 R head size determination protein complement(320383..321135) Escherichia coli O157:H7 str. EC4115 6970951 YP_002268892.1 CDS ECH74115_0316 NC_011353.1 322069 322329 D identified by match to protein family HMM PF05930; phage DNA binding protein 322069..322329 Escherichia coli O157:H7 str. EC4115 6970166 YP_002268893.1 CDS ECH74115_0317 NC_011353.1 322551 322883 D protein ash 322551..322883 Escherichia coli O157:H7 str. EC4115 6969775 YP_002268894.1 CDS ECH74115_0318 NC_011353.1 322880 323101 D hypothetical protein 322880..323101 Escherichia coli O157:H7 str. EC4115 6969294 YP_002268895.1 CDS ECH74115_0319 NC_011353.1 323101 323424 D hypothetical protein 323101..323424 Escherichia coli O157:H7 str. EC4115 6968900 YP_002268896.1 CDS ECH74115_0320 NC_011353.1 323438 325771 D identified by match to protein family HMM PF03288; match to protein family HMM PF08273; match to protein family HMM PF08706; match to protein family HMM TIGR01613; nucleoside triphosphatase, D5 family 323438..325771 Escherichia coli O157:H7 str. EC4115 6967729 YP_002268897.1 CDS ECH74115_0321 NC_011353.1 325904 326860 R hypothetical protein complement(325904..326860) Escherichia coli O157:H7 str. EC4115 6967358 YP_002268898.1 CDS ECH74115_0322 NC_011353.1 327536 328435 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(327536..328435) Escherichia coli O157:H7 str. EC4115 6966871 YP_002268899.1 CDS ECH74115_0323 NC_011353.1 328519 329256 D identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; clavaldehyde dehydrogenase 328519..329256 Escherichia coli O157:H7 str. EC4115 6972190 YP_002268900.1 CDS ECH74115_0324 NC_011353.1 329423 329701 D hypothetical protein 329423..329701 Escherichia coli O157:H7 str. EC4115 6971374 YP_002268901.1 CDS ECH74115_0325 NC_011353.1 329976 330125 D hypothetical protein 329976..330125 Escherichia coli O157:H7 str. EC4115 6968075 YP_002268902.1 CDS ECH74115_0326 NC_011353.1 330404 331288 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR substrate binding domain-containing protein complement(330404..331288) Escherichia coli O157:H7 str. EC4115 6970067 YP_002268903.1 CDS ECH74115_0327 NC_011353.1 331474 332610 D hydrolase of the alpha/beta family protein 331474..332610 Escherichia coli O157:H7 str. EC4115 6970703 YP_002268904.1 CDS ECH74115_0328 NC_011353.1 332686 333879 D identified by match to protein family HMM PF07690; purine ribonucleoside efflux pump NepI 332686..333879 Escherichia coli O157:H7 str. EC4115 6967763 YP_002268905.1 CDS ECH74115_0329 NC_011353.1 334058 335014 R identified by match to protein family HMM PF02625; xanthine dehydrogenase accessory factor complement(334058..335014) Escherichia coli O157:H7 str. EC4115 6971316 YP_002268906.1 CDS ECH74115_0330 NC_011353.1 335024 337222 R identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase family protein, molybdopterin-binding subunit complement(335024..337222) Escherichia coli O157:H7 str. EC4115 6969040 YP_002268907.1 CDS ECH74115_0331 NC_011353.1 337219 338175 R identified by match to protein family HMM PF00941; FAD binding domain in molybdopterin dehydrogenase complement(337219..338175) Escherichia coli O157:H7 str. EC4115 6966845 YP_002268908.1 CDS ECH74115_0332 NC_011353.1 338172 338861 R identified by match to protein family HMM PF00111; match to protein family HMM PF01799; match to protein family HMM TIGR01409; xanthine dehydrogenase iron-sulfur-binding subunit complement(338172..338861) Escherichia coli O157:H7 str. EC4115 6969651 YP_002268909.1 CDS ECH74115_0333 NC_011353.1 339279 339893 D identified by match to protein family HMM PF07274; hypothetical protein 339279..339893 Escherichia coli O157:H7 str. EC4115 6970279 YP_002268910.1 CDS ECH74115_0334 NC_011353.1 340326 340439 R identified by glimmer; hypothetical protein complement(340326..340439) Escherichia coli O157:H7 str. EC4115 6970925 YP_002268911.1 CDS ECH74115_0335 NC_011353.1 340783 341493 R hypothetical protein complement(340783..341493) Escherichia coli O157:H7 str. EC4115 6968278 YP_002268912.1 CDS ECH74115_0336 NC_011353.1 341462 343105 R hypothetical protein complement(341462..343105) Escherichia coli O157:H7 str. EC4115 6969095 YP_002268913.1 CDS ECH74115_0337 NC_011353.1 343095 345620 R hypothetical protein complement(343095..345620) Escherichia coli O157:H7 str. EC4115 6966998 YP_002268914.1 CDS ECH74115_0338 NC_011353.1 345646 346314 R hypothetical protein complement(345646..346314) Escherichia coli O157:H7 str. EC4115 6971294 YP_002268915.1 CDS matB NC_011353.1 346372 346959 R fimbrillin MatB complement(346372..346959) Escherichia coli O157:H7 str. EC4115 6972106 YP_002268916.1 CDS matA NC_011353.1 347034 347576 R identified by match to protein family HMM PF00196; fimbrillin MatA complement(347034..347576) Escherichia coli O157:H7 str. EC4115 6970069 YP_002268917.1 CDS rpmJ NC_011353.1 348662 348802 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(348662..348802) Escherichia coli O157:H7 str. EC4115 6969428 YP_002268918.1 CDS rpmE2 NC_011353.1 348802 349065 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(348802..349065) Escherichia coli O157:H7 str. EC4115 6968035 YP_002268919.1 CDS ECH74115_0343 NC_011353.1 349706 350053 D identified by match to protein family HMM PF05717; IS66 family element, orf2 349706..350053 Escherichia coli O157:H7 str. EC4115 6969328 YP_002268920.1 CDS ECH74115_0344 NC_011353.1 350103 351641 D identified by match to protein family HMM PF03050; IS66 family element, transposase 350103..351641 Escherichia coli O157:H7 str. EC4115 6967078 YP_002268921.1 CDS ECH74115_0345 NC_011353.1 352453 353595 R identified by match to protein family HMM PF00724; FAD/FMN-binding oxidoreductase complement(352453..353595) Escherichia coli O157:H7 str. EC4115 6970167 YP_002268922.1 CDS ECH74115_0346 NC_011353.1 353830 354750 R hypothetical protein complement(353830..354750) Escherichia coli O157:H7 str. EC4115 6971990 YP_002268923.1 CDS ECH74115_0347 NC_011353.1 354907 355833 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 354907..355833 Escherichia coli O157:H7 str. EC4115 6970993 YP_002268924.1 CDS ECH74115_0348 NC_011353.1 356121 356477 R hypothetical protein complement(356121..356477) Escherichia coli O157:H7 str. EC4115 6967865 YP_002268925.1 CDS ECH74115_0349 NC_011353.1 356508 356636 D hypothetical protein 356508..356636 Escherichia coli O157:H7 str. EC4115 6967050 YP_002268926.1 CDS ECH74115_0350 NC_011353.1 356670 357245 R identified by match to protein family HMM PF00248; morphine 6-dehydrogenase complement(356670..357245) Escherichia coli O157:H7 str. EC4115 6970255 YP_002268927.1 CDS ECH74115_0351 NC_011353.1 357811 362064 D identified by match to protein family HMM PF02369; invasin 357811..362064 Escherichia coli O157:H7 str. EC4115 6969469 YP_002268928.1 CDS ECH74115_0352 NC_011353.1 362185 362826 R identified by match to protein family HMM PF06445; AraC family transcriptional regulator complement(362185..362826) Escherichia coli O157:H7 str. EC4115 6971791 YP_002268929.1 CDS ECH74115_0353 NC_011353.1 363291 364160 D identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 363291..364160 Escherichia coli O157:H7 str. EC4115 6971183 YP_002268930.1 CDS ECH74115_0354 NC_011353.1 364320 364913 R identified by match to protein family HMM PF04224; hypothetical protein complement(364320..364913) Escherichia coli O157:H7 str. EC4115 6966849 YP_002268931.1 CDS ECH74115_0355 NC_011353.1 364925 365161 R identified by match to protein family HMM PF07338; hypothetical protein complement(364925..365161) Escherichia coli O157:H7 str. EC4115 6966775 YP_002268932.1 CDS ECH74115_0356 NC_011353.1 365270 366595 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(365270..366595) Escherichia coli O157:H7 str. EC4115 6970090 YP_002268933.1 CDS ECH74115_0357 NC_011353.1 366821 367675 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 366821..367675 Escherichia coli O157:H7 str. EC4115 6970746 YP_002268934.1 CDS ECH74115_0358 NC_011353.1 367834 368004 R identified by glimmer; hypothetical protein complement(367834..368004) Escherichia coli O157:H7 str. EC4115 6969919 YP_002268935.1 CDS ECH74115_0359 NC_011353.1 368202 368921 D identified by match to protein family HMM PF02754; hypothetical protein 368202..368921 Escherichia coli O157:H7 str. EC4115 6970794 YP_002268936.1 CDS ECH74115_0360 NC_011353.1 368932 370359 D identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273; iron-sulfur cluster binding protein 368932..370359 Escherichia coli O157:H7 str. EC4115 6967945 YP_002268937.1 CDS ECH74115_0361 NC_011353.1 370352 371047 D identified by match to protein family HMM PF02589; hypothetical protein 370352..371047 Escherichia coli O157:H7 str. EC4115 6969237 YP_002268938.1 CDS ECH74115_0362 NC_011353.1 371121 371318 R identified by glimmer; hypothetical protein complement(371121..371318) Escherichia coli O157:H7 str. EC4115 6971981 YP_002268939.1 CDS ECH74115_0363 NC_011353.1 371360 371497 D identified by glimmer; hypothetical protein 371360..371497 Escherichia coli O157:H7 str. EC4115 6967163 YP_002268940.1 CDS ECH74115_0367 NC_011353.1 373442 373993 R hypothetical protein complement(373442..373993) Escherichia coli O157:H7 str. EC4115 6970593 YP_002268941.1 CDS ECH74115_0369 NC_011353.1 375033 375170 R hypothetical protein complement(375033..375170) Escherichia coli O157:H7 str. EC4115 6966848 YP_002268942.1 CDS ECH74115_0372 NC_011353.1 376308 376466 R identified by glimmer; hypothetical protein complement(376308..376466) Escherichia coli O157:H7 str. EC4115 6968777 YP_002268943.1 CDS betA NC_011353.1 377103 378791 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(377103..378791) Escherichia coli O157:H7 str. EC4115 6967972 YP_002268944.1 CDS betB NC_011353.1 378805 380277 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(378805..380277) Escherichia coli O157:H7 str. EC4115 6970465 YP_002268945.1 CDS betI NC_011353.1 380291 380878 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(380291..380878) Escherichia coli O157:H7 str. EC4115 6972249 YP_002268946.1 CDS betT NC_011353.1 381007 383040 D proton-motive-force-driven choline transporter; choline transport protein BetT 381007..383040 Escherichia coli O157:H7 str. EC4115 6967316 YP_002268947.1 CDS ECH74115_0377 NC_011353.1 383548 387597 D identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; outer membrane autotransporter 383548..387597 Escherichia coli O157:H7 str. EC4115 6966639 YP_002268948.1 CDS ECH74115_0378 NC_011353.1 387739 388827 D identified by match to protein family HMM PF00196; match to protein family HMM PF00563; LuxR-family transcriptional regulator/cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 387739..388827 Escherichia coli O157:H7 str. EC4115 6970160 YP_002268949.1 CDS ECH74115_0382 NC_011353.1 390657 391262 D identified by match to protein family HMM PF00023; ankyrin 390657..391262 Escherichia coli O157:H7 str. EC4115 6966942 YP_002268950.1 CDS ECH74115_0383 NC_011353.1 391302 392165 D hypothetical protein 391302..392165 Escherichia coli O157:H7 str. EC4115 6971819 YP_002268951.1 CDS ECH74115_0384 NC_011353.1 392155 393702 D identified by match to protein family HMM PF06263; FdrA protein 392155..393702 Escherichia coli O157:H7 str. EC4115 6968136 YP_002268952.1 CDS ECH74115_0385 NC_011353.1 393702 395120 D identified by match to protein family HMM PF06545; hypothetical protein 393702..395120 Escherichia coli O157:H7 str. EC4115 6972070 YP_002268953.1 CDS ECH74115_0386 NC_011353.1 395170 395466 D hypothetical protein 395170..395466 Escherichia coli O157:H7 str. EC4115 6970226 YP_002268954.1 CDS ECH74115_0387 NC_011353.1 395418 395603 D hypothetical protein 395418..395603 Escherichia coli O157:H7 str. EC4115 6970691 YP_002268955.1 CDS ECH74115_0388 NC_011353.1 395635 396585 D identified by match to protein family HMM PF00696; carbamate kinase 395635..396585 Escherichia coli O157:H7 str. EC4115 6968679 YP_002268956.1 CDS ECH74115_0389 NC_011353.1 396595 397977 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 396595..397977 Escherichia coli O157:H7 str. EC4115 6966850 YP_002268957.1 CDS ECH74115_0390 NC_011353.1 398246 398686 D identified by match to protein family HMM PF04266; hypothetical protein 398246..398686 Escherichia coli O157:H7 str. EC4115 6967582 YP_002268958.1 CDS ECH74115_0391 NC_011353.1 398846 398962 R identified by glimmer; hypothetical protein complement(398846..398962) Escherichia coli O157:H7 str. EC4115 6971188 YP_002268959.1 CDS ECH74115_0392 NC_011353.1 398937 399923 D sugar ABC transporter substrate-binding protein 398937..399923 Escherichia coli O157:H7 str. EC4115 6972038 YP_002268960.1 CDS ECH74115_0393 NC_011353.1 399972 401456 D identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 399972..401456 Escherichia coli O157:H7 str. EC4115 6969940 YP_002268961.1 CDS ECH74115_0394 NC_011353.1 401449 402420 D overlaps another CDS with the same product name; identified by match to protein family HMM PF02653; sugar ABC transporter permease 401449..402420 Escherichia coli O157:H7 str. EC4115 6970764 YP_002268962.1 CDS ECH74115_0395 NC_011353.1 402417 403373 D overlaps another CDS with the same product name; identified by match to protein family HMM PF02653; sugar ABC transporter permease 402417..403373 Escherichia coli O157:H7 str. EC4115 6969637 YP_002268963.1 CDS ECH74115_0396 NC_011353.1 403460 404509 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 403460..404509 Escherichia coli O157:H7 str. EC4115 6967854 YP_002268964.1 CDS ECH74115_0397 NC_011353.1 404752 405567 D hypothetical protein 404752..405567 Escherichia coli O157:H7 str. EC4115 6971298 YP_002268965.1 CDS ECH74115_0399 NC_011353.1 406245 406916 R identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/threonine efflux protein complement(406245..406916) Escherichia coli O157:H7 str. EC4115 6972334 YP_002268966.1 CDS ECH74115_0400 NC_011353.1 407063 407338 D identified by match to protein family HMM PF07338; hypothetical protein 407063..407338 Escherichia coli O157:H7 str. EC4115 6966603 YP_002268967.1 CDS ECH74115_0402 NC_011353.1 407365 407484 D identified by glimmer; hypothetical protein 407365..407484 Escherichia coli O157:H7 str. EC4115 6969848 YP_002268968.1 CDS prpR NC_011353.1 407436 409022 R identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329; propionate catabolism operon regulatory protein PrpR complement(407436..409022) Escherichia coli O157:H7 str. EC4115 6971246 YP_002268969.1 CDS prpB NC_011353.1 409261 410151 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 409261..410151 Escherichia coli O157:H7 str. EC4115 6968194 YP_002268970.1 CDS prpC NC_011353.1 410307 411476 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 410307..411476 Escherichia coli O157:H7 str. EC4115 6971924 YP_002268971.1 CDS prpD NC_011353.1 411510 412961 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 411510..412961 Escherichia coli O157:H7 str. EC4115 6966826 YP_002268972.1 CDS prpE NC_011353.1 413001 414887 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 413001..414887 Escherichia coli O157:H7 str. EC4115 6969580 YP_002268973.1 CDS ECH74115_0407 NC_011353.1 414892 415035 D mannitol-1-phosphate 5-dehydrogenase 414892..415035 Escherichia coli O157:H7 str. EC4115 6966694 YP_002268974.1 CDS ECH74115_0408 NC_011353.1 415250 415390 R hypothetical protein complement(415250..415390) Escherichia coli O157:H7 str. EC4115 6971794 YP_002268975.1 CDS codB NC_011353.1 415500 416759 D identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; cytosine permease 415500..416759 Escherichia coli O157:H7 str. EC4115 6968513 YP_002268976.1 CDS codA NC_011353.1 416749 418032 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 416749..418032 Escherichia coli O157:H7 str. EC4115 6967287 YP_002268977.1 CDS cynR NC_011353.1 418165 419064 R controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR complement(418165..419064) Escherichia coli O157:H7 str. EC4115 6970567 YP_002268978.1 CDS cynT NC_011353.1 419174 419833 D identified by match to protein family HMM PF00484; carbonic anhydrase 419174..419833 Escherichia coli O157:H7 str. EC4115 6969988 YP_002268979.1 CDS cynS NC_011353.1 419864 420334 D catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 419864..420334 Escherichia coli O157:H7 str. EC4115 6971120 YP_002268980.1 CDS cynX NC_011353.1 420367 421521 D MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; cyanate transporter 420367..421521 Escherichia coli O157:H7 str. EC4115 6971198 YP_002268981.1 CDS lacA NC_011353.1 421624 422235 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(421624..422235) Escherichia coli O157:H7 str. EC4115 6967500 YP_002268982.1 CDS lacY NC_011353.1 422301 423554 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(422301..423554) Escherichia coli O157:H7 str. EC4115 6970848 YP_002268983.1 CDS lacZ NC_011353.1 423606 426680 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(423606..426680) Escherichia coli O157:H7 str. EC4115 6971849 YP_002268984.1 CDS lacI NC_011353.1 426803 427885 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(426803..427885) Escherichia coli O157:H7 str. EC4115 6971684 YP_002268985.1 CDS ECH74115_0419 NC_011353.1 427922 428875 R identified by match to protein family HMM PF00165; match to protein family HMM PF01965; arac-family transcriptional regulator complement(427922..428875) Escherichia coli O157:H7 str. EC4115 6966674 YP_002268986.1 CDS ECH74115_0420 NC_011353.1 428895 429671 R beta-lactamase fold protein complement(428895..429671) Escherichia coli O157:H7 str. EC4115 6967668 YP_002268987.1 CDS ECH74115_0421 NC_011353.1 429786 430631 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR complement(429786..430631) Escherichia coli O157:H7 str. EC4115 6968640 YP_002268988.1 CDS mhpA NC_011353.1 430810 432474 D catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 430810..432474 Escherichia coli O157:H7 str. EC4115 6968471 YP_002268989.1 CDS mhpB NC_011353.1 432476 433420 D catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 432476..433420 Escherichia coli O157:H7 str. EC4115 6969068 YP_002268990.1 CDS mhpC NC_011353.1 433438 434304 D identified by match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 433438..434304 Escherichia coli O157:H7 str. EC4115 6970159 YP_002268991.1 CDS mhpD NC_011353.1 434314 435123 D catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 434314..435123 Escherichia coli O157:H7 str. EC4115 6971011 YP_002268992.1 CDS mhpF NC_011353.1 435120 436070 D catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 435120..436070 Escherichia coli O157:H7 str. EC4115 6970620 YP_002268993.1 CDS mhpE NC_011353.1 436067 437080 D catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 436067..437080 Escherichia coli O157:H7 str. EC4115 6971409 YP_002268994.1 CDS ECH74115_0428 NC_011353.1 437256 438467 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895; 3-hydroxyphenylpropionic transporter MhpT 437256..438467 Escherichia coli O157:H7 str. EC4115 6969930 YP_002268995.1 CDS ECH74115_0429 NC_011353.1 438569 439108 D hypothetical protein 438569..439108 Escherichia coli O157:H7 str. EC4115 6970735 YP_002268996.1 CDS fghA2 NC_011353.1 439233 440066 R identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase complement(439233..440066) Escherichia coli O157:H7 str. EC4115 6968026 YP_002268997.1 CDS adhC NC_011353.1 440159 441268 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase complement(440159..441268) Escherichia coli O157:H7 str. EC4115 6968833 YP_002268998.1 CDS ECH74115_0432 NC_011353.1 441303 441422 R hypothetical protein complement(441303..441422) Escherichia coli O157:H7 str. EC4115 6971885 YP_002268999.1 CDS fbpC NC_011353.1 441738 442784 R Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit complement(441738..442784) Escherichia coli O157:H7 str. EC4115 6971972 YP_002269000.1 CDS ECH74115_0434 NC_011353.1 442796 444874 R identified by match to protein family HMM PF00528; ABC transporter permease complement(442796..444874) Escherichia coli O157:H7 str. EC4115 6970010 YP_002269001.1 CDS ECH74115_0435 NC_011353.1 444943 445974 R identified by match to protein family HMM PF01547; family 1 extracellular solute-binding protein complement(444943..445974) Escherichia coli O157:H7 str. EC4115 6970779 YP_002269002.1 CDS ECH74115_0436 NC_011353.1 445971 447275 R identified by match to protein family HMM PF07690; regulatory protein UhpC complement(445971..447275) Escherichia coli O157:H7 str. EC4115 6971048 YP_002269003.1 CDS ECH74115_0437 NC_011353.1 447360 448901 R identified by match to protein family HMM PF02518; match to protein family HMM PF05231; match to protein family HMM PF07730; integral membrane sensor signal transduction histidine kinase complement(447360..448901) Escherichia coli O157:H7 str. EC4115 6971873 YP_002269004.1 CDS ECH74115_0438 NC_011353.1 448901 449530 R identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281; transcriptional regulatory protein UhpA complement(448901..449530) Escherichia coli O157:H7 str. EC4115 6971057 YP_002269005.1 CDS ECH74115_0439 NC_011353.1 449635 449754 D identified by glimmer; hypothetical protein 449635..449754 Escherichia coli O157:H7 str. EC4115 6971860 YP_002269006.1 CDS tauA NC_011353.1 449833 450795 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 449833..450795 Escherichia coli O157:H7 str. EC4115 6967671 YP_002269007.1 CDS tauB NC_011353.1 450808 451575 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 450808..451575 Escherichia coli O157:H7 str. EC4115 6968509 YP_002269008.1 CDS tauC NC_011353.1 451572 452399 D identified by match to protein family HMM PF00528; taurine transporter subunit 451572..452399 Escherichia coli O157:H7 str. EC4115 6968694 YP_002269009.1 CDS tauD NC_011353.1 452396 453247 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 452396..453247 Escherichia coli O157:H7 str. EC4115 6969986 YP_002269010.1 CDS hemB NC_011353.1 453354 454328 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(453354..454328) Escherichia coli O157:H7 str. EC4115 6970317 YP_002269011.1 CDS ECH74115_0447 NC_011353.1 457870 458493 D identified by glimmer; DNA-binding transcriptional regulator 457870..458493 Escherichia coli O157:H7 str. EC4115 6969883 YP_002269012.1 CDS ampH NC_011353.1 458494 459651 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(458494..459651) Escherichia coli O157:H7 str. EC4115 6968873 YP_002269013.1 CDS smbA NC_011353.1 460003 461223 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 460003..461223 Escherichia coli O157:H7 str. EC4115 6968402 YP_002269014.1 CDS ECH74115_0450 NC_011353.1 461236 462330 D identified by match to protein family HMM PF07759; lipoprotein 461236..462330 Escherichia coli O157:H7 str. EC4115 6966574 YP_002269015.1 CDS ECH74115_0451 NC_011353.1 462389 462697 R hypothetical protein complement(462389..462697) Escherichia coli O157:H7 str. EC4115 6967188 YP_002269016.1 CDS ECH74115_0452 NC_011353.1 462957 463169 D hypothetical protein 462957..463169 Escherichia coli O157:H7 str. EC4115 6971063 YP_002269017.1 CDS ddl NC_011353.1 463193 464287 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(463193..464287) Escherichia coli O157:H7 str. EC4115 6970241 YP_002269018.1 CDS ECH74115_0454 NC_011353.1 464365 464568 D identified by glimmer; hypothetical protein 464365..464568 Escherichia coli O157:H7 str. EC4115 6970862 YP_002269019.1 CDS ECH74115_0455 NC_011353.1 464582 464704 D identified by glimmer; hypothetical protein 464582..464704 Escherichia coli O157:H7 str. EC4115 6967465 YP_002269020.1 CDS ECH74115_0456 NC_011353.1 464750 465010 D hypothetical protein 464750..465010 Escherichia coli O157:H7 str. EC4115 6972140 YP_002269021.1 CDS phoA NC_011353.1 465111 466526 D identified by match to protein family HMM PF00245; alkaline phosphatase 465111..466526 Escherichia coli O157:H7 str. EC4115 6971494 YP_002269022.1 CDS psiF NC_011353.1 466645 466965 D identified by match to protein family HMM PF07769; hypothetical protein 466645..466965 Escherichia coli O157:H7 str. EC4115 6969249 YP_002269023.1 CDS adrA NC_011353.1 467067 468182 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 467067..468182 Escherichia coli O157:H7 str. EC4115 6968632 YP_002269024.1 CDS proC NC_011353.1 468199 469008 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(468199..469008) Escherichia coli O157:H7 str. EC4115 6967667 YP_002269025.1 CDS ECH74115_0461 NC_011353.1 469128 469586 D identified by match to protein family HMM PF02639; hypothetical protein 469128..469586 Escherichia coli O157:H7 str. EC4115 6967599 YP_002269026.1 CDS aroL NC_011353.1 469769 470293 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 469769..470293 Escherichia coli O157:H7 str. EC4115 6966803 YP_002269027.1 CDS ECH74115_0463 NC_011353.1 470343 470534 D hypothetical protein 470343..470534 Escherichia coli O157:H7 str. EC4115 6971701 YP_002269028.1 CDS aroM NC_011353.1 470792 471469 D identified by match to protein family HMM PF07302; hypothetical protein 470792..471469 Escherichia coli O157:H7 str. EC4115 6970847 YP_002269029.1 CDS ECH74115_0465 NC_011353.1 471541 471825 D identified by match to protein family HMM PF06865; hypothetical protein 471541..471825 Escherichia coli O157:H7 str. EC4115 6970762 YP_002269030.1 CDS ECH74115_0466 NC_011353.1 472083 474248 D identified by glimmer; hypothetical protein 472083..474248 Escherichia coli O157:H7 str. EC4115 6967156 YP_002269031.1 CDS rdgC NC_011353.1 474779 475690 R Required for efficient pilin antigenic variation; recombination associated protein complement(474779..475690) Escherichia coli O157:H7 str. EC4115 6971721 YP_002269032.1 CDS mak NC_011353.1 475815 476723 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 475815..476723 Escherichia coli O157:H7 str. EC4115 6971116 YP_002269033.1 CDS araJ NC_011353.1 476866 478134 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(476866..478134) Escherichia coli O157:H7 str. EC4115 6969012 YP_002269034.1 CDS sbcC NC_011353.1 478176 481319 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC complement(478176..481319) Escherichia coli O157:H7 str. EC4115 6968192 YP_002269035.1 CDS sbcD NC_011353.1 481316 482518 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD complement(481316..482518) Escherichia coli O157:H7 str. EC4115 6967715 YP_002269036.1 CDS ECH74115_0474 NC_011353.1 482504 482635 D identified by glimmer; hypothetical protein 482504..482635 Escherichia coli O157:H7 str. EC4115 6971128 YP_002269037.1 CDS phoB NC_011353.1 482708 483397 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 482708..483397 Escherichia coli O157:H7 str. EC4115 6970594 YP_002269038.1 CDS phoR NC_011353.1 483455 484750 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 483455..484750 Escherichia coli O157:H7 str. EC4115 6969745 YP_002269039.1 CDS ECH74115_0477 NC_011353.1 484963 485112 R hypothetical protein complement(484963..485112) Escherichia coli O157:H7 str. EC4115 6969292 YP_002269040.1 CDS brnQ NC_011353.1 485157 486476 D identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 485157..486476 Escherichia coli O157:H7 str. EC4115 6968850 YP_002269041.1 CDS proY NC_011353.1 486552 487925 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 486552..487925 Escherichia coli O157:H7 str. EC4115 6968590 YP_002269042.1 CDS malZ NC_011353.1 488084 489898 D identified by match to protein family HMM PF00128; maltodextrin glucosidase 488084..489898 Escherichia coli O157:H7 str. EC4115 6967572 YP_002269043.1 CDS ECH74115_0481 NC_011353.1 489968 490135 D identified by glimmer; hypothetical protein 489968..490135 Escherichia coli O157:H7 str. EC4115 6966785 YP_002269044.1 CDS ECH74115_0482 NC_011353.1 490196 490321 R identified by glimmer; hypothetical protein complement(490196..490321) Escherichia coli O157:H7 str. EC4115 6971967 YP_002269045.1 CDS ECH74115_0483 NC_011353.1 490422 491531 D identified by glimmer; hypothetical protein 490422..491531 Escherichia coli O157:H7 str. EC4115 6970447 YP_002269046.1 CDS acpH NC_011353.1 491552 492133 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase complement(491552..492133) Escherichia coli O157:H7 str. EC4115 6970671 YP_002269047.1 CDS queA NC_011353.1 492226 493296 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 492226..493296 Escherichia coli O157:H7 str. EC4115 6969888 YP_002269048.1 CDS tgt NC_011353.1 493351 494478 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 493351..494478 Escherichia coli O157:H7 str. EC4115 6971490 YP_002269049.1 CDS yajC NC_011353.1 494501 494833 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 494501..494833 Escherichia coli O157:H7 str. EC4115 6970596 YP_002269050.1 CDS secD NC_011353.1 494861 496708 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 494861..496708 Escherichia coli O157:H7 str. EC4115 6966680 YP_002269051.1 CDS secF NC_011353.1 496719 497690 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 496719..497690 Escherichia coli O157:H7 str. EC4115 6972132 YP_002269052.1 CDS ECH74115_0490 NC_011353.1 497842 498084 D identified by match to protein family HMM PF03693; match to protein family HMM TIGR02606; addiction module antidote protein 497842..498084 Escherichia coli O157:H7 str. EC4115 6967260 YP_002269053.1 CDS ECH74115_0491 NC_011353.1 498077 498358 D identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 498077..498358 Escherichia coli O157:H7 str. EC4115 6966650 YP_002269054.1 CDS ECH74115_0492 NC_011353.1 498446 498793 D identified by match to protein family HMM PF01844; hypothetical protein 498446..498793 Escherichia coli O157:H7 str. EC4115 6968855 YP_002269055.1 CDS tsx NC_011353.1 498970 499854 R identified by match to protein family HMM PF03502; nucleoside-specific channel-forming protein Tsx complement(498970..499854) Escherichia coli O157:H7 str. EC4115 6968149 YP_002269056.1 CDS ECH74115_0494 NC_011353.1 500153 500692 R hypothetical protein complement(500153..500692) Escherichia coli O157:H7 str. EC4115 6969618 YP_002269057.1 CDS nrdR NC_011353.1 500843 501292 D identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 500843..501292 Escherichia coli O157:H7 str. EC4115 6970412 YP_002269058.1 CDS ribD NC_011353.1 501296 502399 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 501296..502399 Escherichia coli O157:H7 str. EC4115 6967169 YP_002269059.1 CDS ribH NC_011353.1 502488 502958 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 502488..502958 Escherichia coli O157:H7 str. EC4115 6966568 YP_002269060.1 CDS nusB NC_011353.1 502978 503397 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 502978..503397 Escherichia coli O157:H7 str. EC4115 6971309 YP_002269061.1 CDS thiL NC_011353.1 503475 504452 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 503475..504452 Escherichia coli O157:H7 str. EC4115 6967794 YP_002269062.1 CDS pgpA NC_011353.1 504439 504945 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 504439..504945 Escherichia coli O157:H7 str. EC4115 6969576 YP_002269063.1 CDS ECH74115_0501 NC_011353.1 505123 506694 R identified by match to protein family HMM PF00805; hypothetical protein complement(505123..506694) Escherichia coli O157:H7 str. EC4115 6971853 YP_002269064.1 CDS ECH74115_0502 NC_011353.1 506925 507899 R identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family complement(506925..507899) Escherichia coli O157:H7 str. EC4115 6967954 YP_002269065.1 CDS dxs NC_011353.1 507954 509816 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(507954..509816) Escherichia coli O157:H7 str. EC4115 6970204 YP_002269066.1 CDS ispA NC_011353.1 509841 510740 R identified by match to protein family HMM PF00348; geranyltranstransferase complement(509841..510740) Escherichia coli O157:H7 str. EC4115 6969331 YP_002269067.1 CDS xseB NC_011353.1 510740 510982 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(510740..510982) Escherichia coli O157:H7 str. EC4115 6968705 YP_002269068.1 CDS ECH74115_0506 NC_011353.1 511088 511201 R identified by glimmer; hypothetical protein complement(511088..511201) Escherichia coli O157:H7 str. EC4115 6969177 YP_002269069.1 CDS thiI NC_011353.1 511188 512636 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 511188..512636 Escherichia coli O157:H7 str. EC4115 6967468 YP_002269070.1 CDS thiJ NC_011353.1 512690 513280 R identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; DJ-1 family protein complement(512690..513280) Escherichia coli O157:H7 str. EC4115 6967965 YP_002269071.1 CDS panE NC_011353.1 513243 514154 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(513243..514154) Escherichia coli O157:H7 str. EC4115 6968776 YP_002269072.1 CDS ECH74115_0510 NC_011353.1 514322 514813 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 514322..514813 Escherichia coli O157:H7 str. EC4115 6969923 YP_002269073.1 CDS ECH74115_0511 NC_011353.1 514941 516305 R identified by match to protein family HMM PF07690; major facilitator family transporter complement(514941..516305) Escherichia coli O157:H7 str. EC4115 6970669 YP_002269074.1 CDS cyoE NC_011353.1 516454 517389 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(516454..517389) Escherichia coli O157:H7 str. EC4115 6971469 YP_002269075.1 CDS cyoD NC_011353.1 517356 517685 R identified by match to protein family HMM PF03626; match to protein family HMM TIGR02847; cytochrome o ubiquinol oxidase subunit IV complement(517356..517685) Escherichia coli O157:H7 str. EC4115 6972031 YP_002269076.1 CDS cyoC NC_011353.1 517685 518299 R identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842; cytochrome o ubiquinol oxidase subunit III complement(517685..518299) Escherichia coli O157:H7 str. EC4115 6966760 YP_002269077.1 CDS cyoB NC_011353.1 518289 520280 R identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843; cytochrome o ubiquinol oxidase subunit I complement(518289..520280) Escherichia coli O157:H7 str. EC4115 6967583 YP_002269078.1 CDS cyoA NC_011353.1 520302 521249 R identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433; cytochrome o ubiquinol oxidase subunit II complement(520302..521249) Escherichia coli O157:H7 str. EC4115 6969417 YP_002269079.1 CDS ampG NC_011353.1 521709 523184 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(521709..523184) Escherichia coli O157:H7 str. EC4115 6969315 YP_002269080.1 CDS ECH74115_0518 NC_011353.1 523228 523806 R identified by match to protein family HMM PF03923; hypothetical protein complement(523228..523806) Escherichia coli O157:H7 str. EC4115 6971379 YP_002269081.1 CDS ECH74115_0519 NC_011353.1 523856 523987 R identified by glimmer; hypothetical protein complement(523856..523987) Escherichia coli O157:H7 str. EC4115 6970531 YP_002269082.1 CDS ECH74115_0520 NC_011353.1 524111 524428 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 524111..524428 Escherichia coli O157:H7 str. EC4115 6967563 YP_002269083.1 CDS ECH74115_0521 NC_011353.1 524437 524625 D identified by glimmer; hypothetical protein 524437..524625 Escherichia coli O157:H7 str. EC4115 6966789 YP_002269084.1 CDS tig NC_011353.1 524772 526070 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 524772..526070 Escherichia coli O157:H7 str. EC4115 6968861 YP_002269085.1 CDS clpX NC_011353.1 527064 528338 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 527064..528338 Escherichia coli O157:H7 str. EC4115 6970141 YP_002269086.1 CDS lon NC_011353.1 528481 530880 D identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763; DNA-binding ATP-dependent protease La 528481..530880 Escherichia coli O157:H7 str. EC4115 6969992 YP_002269087.1 CDS hupB NC_011353.1 531089 531361 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 531089..531361 Escherichia coli O157:H7 str. EC4115 6971132 YP_002269088.1 CDS ppiD NC_011353.1 531553 533424 D identified by match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase 531553..533424 Escherichia coli O157:H7 str. EC4115 6970335 YP_002269089.1 CDS ECH74115_0528 NC_011353.1 533575 533946 D identified by match to protein family HMM TIGR00426; competence protein ComEA 533575..533946 Escherichia coli O157:H7 str. EC4115 6966714 YP_002269090.1 CDS ECH74115_0529 NC_011353.1 534052 534450 D identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; thioesterase family protein 534052..534450 Escherichia coli O157:H7 str. EC4115 6971861 YP_002269091.1 CDS queC NC_011353.1 534502 535197 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(534502..535197) Escherichia coli O157:H7 str. EC4115 6967822 YP_002269092.1 CDS ECH74115_0531 NC_011353.1 535262 536962 R identified by match to protein family HMM PF00496; extracellular solute-binding protein complement(535262..536962) Escherichia coli O157:H7 str. EC4115 6967412 YP_002269093.1 CDS ECH74115_0532 NC_011353.1 536918 537037 D identified by glimmer; hypothetical protein 536918..537037 Escherichia coli O157:H7 str. EC4115 6969137 YP_002269094.1 CDS cof NC_011353.1 537062 537880 D identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hydrolase Cof 537062..537880 Escherichia coli O157:H7 str. EC4115 6968343 YP_002269095.1 CDS ECH74115_0533 NC_011353.1 537860 537985 R identified by glimmer; hypothetical protein complement(537860..537985) Escherichia coli O157:H7 str. EC4115 6966980 YP_002269096.1 CDS ECH74115_0535 NC_011353.1 538032 538490 D identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 538032..538490 Escherichia coli O157:H7 str. EC4115 6967682 YP_002269097.1 CDS mdlA NC_011353.1 538520 540292 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 538520..540292 Escherichia coli O157:H7 str. EC4115 6968200 YP_002269098.1 CDS mdlB NC_011353.1 540285 542066 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 540285..542066 Escherichia coli O157:H7 str. EC4115 6968344 YP_002269099.1 CDS ECH74115_0538 NC_011353.1 542080 542220 R identified by glimmer; hypothetical protein complement(542080..542220) Escherichia coli O157:H7 str. EC4115 6968253 YP_002269100.1 CDS glnK NC_011353.1 542247 542585 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 542247..542585 Escherichia coli O157:H7 str. EC4115 6969938 YP_002269101.1 CDS amt NC_011353.1 542615 543901 D identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 542615..543901 Escherichia coli O157:H7 str. EC4115 6972050 YP_002269102.1 CDS tesB NC_011353.1 543950 544810 R identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase II complement(543950..544810) Escherichia coli O157:H7 str. EC4115 6970861 YP_002269103.1 CDS ECH74115_0542 NC_011353.1 544889 545011 D identified by glimmer; hypothetical protein 544889..545011 Escherichia coli O157:H7 str. EC4115 6967445 YP_002269104.1 CDS ECH74115_0543 NC_011353.1 545043 545600 D lipoprotein 545043..545600 Escherichia coli O157:H7 str. EC4115 6967132 YP_002269105.1 CDS ECH74115_0544 NC_011353.1 545633 545944 R identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA-[protein]-cysteine S-methyltransferase complement(545633..545944) Escherichia coli O157:H7 str. EC4115 6969367 YP_002269106.1 CDS ECH74115_0546 NC_011353.1 546323 546676 D identified by match to protein family HMM PF07237; hypothetical protein 546323..546676 Escherichia coli O157:H7 str. EC4115 6972260 YP_002269107.1 CDS ECH74115_0547 NC_011353.1 546718 548268 R identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein complement(546718..548268) Escherichia coli O157:H7 str. EC4115 6970264 YP_002269108.1 CDS ECH74115_0548 NC_011353.1 548432 548902 R hypothetical protein complement(548432..548902) Escherichia coli O157:H7 str. EC4115 6971269 YP_002269109.1 CDS maa NC_011353.1 549018 549569 R identified by match to protein family HMM PF00132; maltose O-acetyltransferase complement(549018..549569) Escherichia coli O157:H7 str. EC4115 6971159 YP_002269110.1 CDS ECH74115_0550 NC_011353.1 549741 549959 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(549741..549959) Escherichia coli O157:H7 str. EC4115 6970983 YP_002269111.1 CDS ECH74115_0551 NC_011353.1 549985 550359 R hypothetical protein complement(549985..550359) Escherichia coli O157:H7 str. EC4115 6971545 YP_002269112.1 CDS acrB NC_011353.1 550905 554054 R identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; acriflavine resistance protein B complement(550905..554054) Escherichia coli O157:H7 str. EC4115 6967174 YP_002269113.1 CDS acrA NC_011353.1 554077 555306 R identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein A complement(554077..555306) Escherichia coli O157:H7 str. EC4115 6967271 YP_002269114.1 CDS acrR NC_011353.1 555412 556059 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 555412..556059 Escherichia coli O157:H7 str. EC4115 6969188 YP_002269115.1 CDS kefA NC_011353.1 556193 559549 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 556193..559549 Escherichia coli O157:H7 str. EC4115 6969959 YP_002269116.1 CDS ECH74115_0556 NC_011353.1 559588 559752 R hypothetical protein complement(559588..559752) Escherichia coli O157:H7 str. EC4115 6969665 YP_002269117.1 CDS priC NC_011353.1 559766 560293 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(559766..560293) Escherichia coli O157:H7 str. EC4115 6971574 YP_002269118.1 CDS ECH74115_0558 NC_011353.1 560363 560740 D identified by match to protein family HMM PF04304; hypothetical protein 560363..560740 Escherichia coli O157:H7 str. EC4115 6971595 YP_002269119.1 CDS apt NC_011353.1 560893 561444 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 560893..561444 Escherichia coli O157:H7 str. EC4115 6969551 YP_002269120.1 CDS dnaX NC_011353.1 561573 563504 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 561573..563504 Escherichia coli O157:H7 str. EC4115 6969946 YP_002269121.1 CDS ECH74115_0562 NC_011353.1 563557 563886 D identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 563557..563886 Escherichia coli O157:H7 str. EC4115 6970597 YP_002269122.1 CDS recR NC_011353.1 563886 564491 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 563886..564491 Escherichia coli O157:H7 str. EC4115 6969111 YP_002269123.1 CDS htpG NC_011353.1 564601 566475 D molecular chaperone; heat shock protein 90 564601..566475 Escherichia coli O157:H7 str. EC4115 6966891 YP_002269124.1 CDS ECH74115_0565 NC_011353.1 566480 566596 D identified by glimmer; hypothetical protein 566480..566596 Escherichia coli O157:H7 str. EC4115 6967438 YP_002269125.1 CDS adk NC_011353.1 566596 567300 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 566596..567300 Escherichia coli O157:H7 str. EC4115 6970903 YP_002269126.1 CDS hemH NC_011353.1 567432 568394 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 567432..568394 Escherichia coli O157:H7 str. EC4115 6968078 YP_002269127.1 CDS aes NC_011353.1 568391 569350 R identified by match to protein family HMM PF07859; acetyl esterase complement(568391..569350) Escherichia coli O157:H7 str. EC4115 6971546 YP_002269128.1 CDS gsk NC_011353.1 569502 570806 D identified by match to protein family HMM PF00294; inosine kinase 569502..570806 Escherichia coli O157:H7 str. EC4115 6969832 YP_002269129.1 CDS ECH74115_0570 NC_011353.1 570939 572615 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(570939..572615) Escherichia coli O157:H7 str. EC4115 6971043 YP_002269130.1 CDS fsr NC_011353.1 572852 574072 R identified by match to protein family HMM PF07690; fosmidomycin resistance protein complement(572852..574072) Escherichia coli O157:H7 str. EC4115 6968736 YP_002269131.1 CDS ushA NC_011353.1 574290 575942 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 574290..575942 Escherichia coli O157:H7 str. EC4115 6969359 YP_002269132.1 CDS ECH74115_0573 NC_011353.1 575979 576458 R identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011; hypothetical protein complement(575979..576458) Escherichia coli O157:H7 str. EC4115 6968563 YP_002269133.1 CDS ECH74115_0574 NC_011353.1 576662 577456 R identified by match to protein family HMM PF07446; GumN family protein complement(576662..577456) Escherichia coli O157:H7 str. EC4115 6972294 YP_002269134.1 CDS ECH74115_0576 NC_011353.1 577540 577935 D identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; HigA family addiction module antidote protein 577540..577935 Escherichia coli O157:H7 str. EC4115 6969821 YP_002269135.1 CDS copA NC_011353.1 578150 580654 R identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper exporting ATPase complement(578150..580654) Escherichia coli O157:H7 str. EC4115 6971866 YP_002269136.1 CDS glsA1 NC_011353.1 580916 581848 D catalyzes the formation of glutamate from glutamine; glutaminase 580916..581848 Escherichia coli O157:H7 str. EC4115 6971007 YP_002269137.1 CDS ECH74115_0579 NC_011353.1 581851 583143 D identified by match to protein family HMM PF00324; match to protein family HMM PF03845; amino acid permease family protein 581851..583143 Escherichia coli O157:H7 str. EC4115 6968223 YP_002269138.1 CDS ECH74115_0580 NC_011353.1 583481 584836 D identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844; outer membrane transport protein 583481..584836 Escherichia coli O157:H7 str. EC4115 6968317 YP_002269139.1 CDS ECH74115_0581 NC_011353.1 584939 589324 D PKD domain-containing protein 584939..589324 Escherichia coli O157:H7 str. EC4115 6969304 YP_002269140.1 CDS ECH74115_0584 NC_011353.1 605092 607254 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR03375; type I secretion system ATPase family protein 605092..607254 Escherichia coli O157:H7 str. EC4115 6971144 YP_002269141.1 CDS ECH74115_0585 NC_011353.1 607251 608426 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843; membrane spanning export protein 607251..608426 Escherichia coli O157:H7 str. EC4115 6971827 YP_002269142.1 CDS cueR NC_011353.1 608423 608830 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 608423..608830 Escherichia coli O157:H7 str. EC4115 6970702 YP_002269143.1 CDS ECH74115_0587 NC_011353.1 608834 609001 R identified by glimmer; hypothetical protein complement(608834..609001) Escherichia coli O157:H7 str. EC4115 6970216 YP_002269144.1 CDS ECH74115_0588 NC_011353.1 609034 609456 R lipoprotein complement(609034..609456) Escherichia coli O157:H7 str. EC4115 6968980 YP_002269145.1 CDS ECH74115_0589 NC_011353.1 609541 610557 R identified by match to protein family HMM PF03895; hypothetical protein complement(609541..610557) Escherichia coli O157:H7 str. EC4115 6971416 YP_002269146.1 CDS ECH74115_0590 NC_011353.1 610655 610777 R identified by glimmer; hypothetical protein complement(610655..610777) Escherichia coli O157:H7 str. EC4115 6969307 YP_002269147.1 CDS ECH74115_0591 NC_011353.1 610924 611286 D hypothetical protein 610924..611286 Escherichia coli O157:H7 str. EC4115 6970091 YP_002269148.1 CDS ECH74115_0592 NC_011353.1 611465 611923 R identified by match to protein family HMM PF01957; nodulation efficiency family protein complement(611465..611923) Escherichia coli O157:H7 str. EC4115 6968198 YP_002269149.1 CDS ECH74115_0593 NC_011353.1 611920 612837 R identified by match to protein family HMM PF01145; SPFH domain/band 7 family protein complement(611920..612837) Escherichia coli O157:H7 str. EC4115 6968447 YP_002269150.1 CDS ECH74115_0594 NC_011353.1 612983 613660 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 612983..613660 Escherichia coli O157:H7 str. EC4115 6966586 YP_002269151.1 CDS ECH74115_0595 NC_011353.1 613647 614426 D identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245; hypothetical protein 613647..614426 Escherichia coli O157:H7 str. EC4115 6967594 YP_002269152.1 CDS ybbN NC_011353.1 614489 615343 R identified by match to protein family HMM PF00085; protein YbbN complement(614489..615343) Escherichia coli O157:H7 str. EC4115 6971366 YP_002269153.1 CDS ECH74115_0597 NC_011353.1 615404 616213 R identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase complement(615404..616213) Escherichia coli O157:H7 str. EC4115 6971622 YP_002269154.1 CDS tesA NC_011353.1 616203 616826 R identified by match to protein family HMM PF00657; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(616203..616826) Escherichia coli O157:H7 str. EC4115 6969885 YP_002269155.1 CDS ECH74115_0599 NC_011353.1 616797 617483 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 616797..617483 Escherichia coli O157:H7 str. EC4115 6967076 YP_002269156.1 CDS ECH74115_0600 NC_011353.1 617480 619894 D identified by match to protein family HMM PF02687; efflux ABC transporter permease 617480..619894 Escherichia coli O157:H7 str. EC4115 6970152 YP_002269157.1 CDS ECH74115_0601 NC_011353.1 620324 624520 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 620324..624520 Escherichia coli O157:H7 str. EC4115 6969303 YP_002269158.1 CDS selU NC_011353.1 625992 627086 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(625992..627086) Escherichia coli O157:H7 str. EC4115 6971214 YP_002269159.1 CDS ECH74115_0605 NC_011353.1 627155 628081 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(627155..628081) Escherichia coli O157:H7 str. EC4115 6971788 YP_002269160.1 CDS allA NC_011353.1 628311 628793 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 628311..628793 Escherichia coli O157:H7 str. EC4115 6967070 YP_002269161.1 CDS allR NC_011353.1 628916 629686 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 628916..629686 Escherichia coli O157:H7 str. EC4115 6967609 YP_002269162.1 CDS gcl NC_011353.1 629776 631557 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 629776..631557 Escherichia coli O157:H7 str. EC4115 6971261 YP_002269163.1 CDS hyi NC_011353.1 631570 632346 D identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234; hydroxypyruvate isomerase 631570..632346 Escherichia coli O157:H7 str. EC4115 6971669 YP_002269164.1 CDS ECH74115_0610 NC_011353.1 632447 633325 D identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505; 2-hydroxy-3-oxopropionate reductase 632447..633325 Escherichia coli O157:H7 str. EC4115 6967993 YP_002269165.1 CDS ECH74115_0611 NC_011353.1 633494 634885 D identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; allantoin permease 633494..634885 Escherichia coli O157:H7 str. EC4115 6967576 YP_002269166.1 CDS ECH74115_0614 NC_011353.1 636340 637641 D identified by match to protein family HMM PF00860; purine permease YbbY 636340..637641 Escherichia coli O157:H7 str. EC4115 6971958 YP_002269167.1 CDS ECH74115_0615 NC_011353.1 637663 638808 D identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 637663..638808 Escherichia coli O157:H7 str. EC4115 6971387 YP_002269168.1 CDS ECH74115_0616 NC_011353.1 639036 639821 R identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214; hypothetical protein complement(639036..639821) Escherichia coli O157:H7 str. EC4115 6967350 YP_002269169.1 CDS allC NC_011353.1 639832 641067 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(639832..641067) Escherichia coli O157:H7 str. EC4115 6966679 YP_002269170.1 CDS allD NC_011353.1 641089 642138 R identified by match to protein family HMM PF02615; match to protein family HMM TIGR03175; ureidoglycolate dehydrogenase complement(641089..642138) Escherichia coli O157:H7 str. EC4115 6968967 YP_002269171.1 CDS ECH74115_0619 NC_011353.1 642455 644122 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 642455..644122 Escherichia coli O157:H7 str. EC4115 6970004 YP_002269172.1 CDS ECH74115_0620 NC_011353.1 644132 645391 D identified by match to protein family HMM PF06545; hypothetical protein 644132..645391 Escherichia coli O157:H7 str. EC4115 6967901 YP_002269173.1 CDS ECH74115_0621 NC_011353.1 645402 646217 D hypothetical protein 645402..646217 Escherichia coli O157:H7 str. EC4115 6971232 YP_002269174.1 CDS arcC NC_011353.1 646214 647107 D identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; carbamate kinase 646214..647107 Escherichia coli O157:H7 str. EC4115 6969185 YP_002269175.1 CDS purK NC_011353.1 647246 648313 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(647246..648313) Escherichia coli O157:H7 str. EC4115 6966728 YP_002269176.1 CDS purE NC_011353.1 648310 648819 R identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit complement(648310..648819) Escherichia coli O157:H7 str. EC4115 6970125 YP_002269177.1 CDS lpxH NC_011353.1 648937 649659 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(648937..649659) Escherichia coli O157:H7 str. EC4115 6968132 YP_002269178.1 CDS ppiB NC_011353.1 649662 650156 R identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase B complement(649662..650156) Escherichia coli O157:H7 str. EC4115 6970002 YP_002269179.1 CDS cysS NC_011353.1 650330 651715 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 650330..651715 Escherichia coli O157:H7 str. EC4115 6970773 YP_002269180.1 CDS ECH74115_0628 NC_011353.1 651751 652272 R identified by match to protein family HMM PF04307; hypothetical protein complement(651751..652272) Escherichia coli O157:H7 str. EC4115 6968017 YP_002269181.1 CDS ECH74115_0629 NC_011353.1 652380 652592 R hypothetical protein complement(652380..652592) Escherichia coli O157:H7 str. EC4115 6971429 YP_002269182.1 CDS folD NC_011353.1 652594 653460 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(652594..653460) Escherichia coli O157:H7 str. EC4115 6968258 YP_002269183.1 CDS ECH74115_0631 NC_011353.1 653940 654482 D identified by match to protein family HMM PF00419; type-1 fimbrial protein-like protein 653940..654482 Escherichia coli O157:H7 str. EC4115 6969773 YP_002269184.1 CDS ECH74115_0632 NC_011353.1 654702 655394 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC-like protein 654702..655394 Escherichia coli O157:H7 str. EC4115 6967406 YP_002269185.1 CDS sfmD NC_011353.1 655425 658034 D identified by match to protein family HMM PF00577; outer membrane usher protein SfmD 655425..658034 Escherichia coli O157:H7 str. EC4115 6968250 YP_002269186.1 CDS ECH74115_0634 NC_011353.1 658047 659054 D mannose binding protein FimH-like protein 658047..659054 Escherichia coli O157:H7 str. EC4115 6972244 YP_002269187.1 CDS ECH74115_0635 NC_011353.1 659383 659580 D fimbrial protein 659383..659580 Escherichia coli O157:H7 str. EC4115 6966567 YP_002269188.1 CDS fimZ NC_011353.1 659583 660215 R activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ complement(659583..660215) Escherichia coli O157:H7 str. EC4115 6971377 YP_002269189.1 CDS ECH74115_0637 NC_011353.1 660270 660425 D identified by glimmer; hypothetical protein 660270..660425 Escherichia coli O157:H7 str. EC4115 6972179 YP_002269190.1 CDS ECH74115_0639 NC_011353.1 660580 661341 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(660580..661341) Escherichia coli O157:H7 str. EC4115 6972390 YP_002269191.1 CDS ECH74115_0640 NC_011353.1 661524 662414 R hypothetical protein complement(661524..662414) Escherichia coli O157:H7 str. EC4115 6966925 YP_002269192.1 CDS ECH74115_0641 NC_011353.1 662415 665387 R identified by match to protein family HMM PF00515; match to protein family HMM PF07719; bacteriophage N4 receptor, outer membrane subunit complement(662415..665387) Escherichia coli O157:H7 str. EC4115 6970240 YP_002269193.1 CDS nfrB NC_011353.1 665374 667611 R identified by match to protein family HMM PF05157; bacteriophage N4 adsorption protein B complement(665374..667611) Escherichia coli O157:H7 str. EC4115 6968533 YP_002269194.1 CDS ECH74115_0643 NC_011353.1 667877 669013 R identified by match to protein family HMM PF01609; ISEc4, transposase complement(667877..669013) Escherichia coli O157:H7 str. EC4115 6971845 YP_002269195.1 CDS ECH74115_0644 NC_011353.1 669228 669437 R hypothetical protein complement(669228..669437) Escherichia coli O157:H7 str. EC4115 6969446 YP_002269196.1 CDS ECH74115_0645 NC_011353.1 669476 670810 R identified by match to protein family HMM PF05593; match to protein family HMM TIGR01643; Rhs core protein complement(669476..670810) Escherichia coli O157:H7 str. EC4115 6971888 YP_002269197.1 CDS ECH74115_0647 NC_011353.1 671403 676253 R identified by match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein complement(671403..676253) Escherichia coli O157:H7 str. EC4115 6967509 YP_002269198.1 CDS ECH74115_0648 NC_011353.1 676273 676734 R identified by match to protein family HMM PF08786; hypothetical protein complement(676273..676734) Escherichia coli O157:H7 str. EC4115 6967732 YP_002269199.1 CDS ECH74115_0649 NC_011353.1 676762 678663 R identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein complement(676762..678663) Escherichia coli O157:H7 str. EC4115 6968369 YP_002269200.1 CDS cusS NC_011353.1 679257 680705 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; sensor kinase CusS complement(679257..680705) Escherichia coli O157:H7 str. EC4115 6968954 YP_002269201.1 CDS cusR NC_011353.1 680695 681378 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(680695..681378) Escherichia coli O157:H7 str. EC4115 6969314 YP_002269202.1 CDS ECH74115_0652 NC_011353.1 681425 681580 D identified by glimmer; hypothetical protein 681425..681580 Escherichia coli O157:H7 str. EC4115 6969422 YP_002269203.1 CDS cusC NC_011353.1 681535 682917 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 681535..682917 Escherichia coli O157:H7 str. EC4115 6970337 YP_002269204.1 CDS cusF NC_011353.1 682941 683273 D copper-binding protein 682941..683273 Escherichia coli O157:H7 str. EC4115 6971150 YP_002269205.1 CDS cusB NC_011353.1 683289 684512 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 683289..684512 Escherichia coli O157:H7 str. EC4115 6966936 YP_002269206.1 CDS cusA NC_011353.1 684524 687661 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; cation efflux system protein cusA 684524..687661 Escherichia coli O157:H7 str. EC4115 6971531 YP_002269207.1 CDS pheP NC_011353.1 687727 689139 D identified by match to protein family HMM PF00324; phenylalanine transporter 687727..689139 Escherichia coli O157:H7 str. EC4115 6967213 YP_002269208.1 CDS ECH74115_0658 NC_011353.1 689207 690454 R identified by match to protein family HMM PF00924; transporter small conductance mechanosensitive ion channel (MscS) family complement(689207..690454) Escherichia coli O157:H7 str. EC4115 6967797 YP_002269209.1 CDS nfnB NC_011353.1 690562 691215 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(690562..691215) Escherichia coli O157:H7 str. EC4115 6970061 YP_002269210.1 CDS ECH74115_0660 NC_011353.1 691309 691677 R identified by match to protein family HMM PF04237; hypothetical protein complement(691309..691677) Escherichia coli O157:H7 str. EC4115 6972048 YP_002269211.1 CDS ECH74115_0661 NC_011353.1 691742 691990 R identified by match to protein family HMM PF06643; lipoprotein complement(691742..691990) Escherichia coli O157:H7 str. EC4115 6969487 YP_002269212.1 CDS ECH74115_0662 NC_011353.1 692056 693174 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(692056..693174) Escherichia coli O157:H7 str. EC4115 6970000 YP_002269213.1 CDS ECH74115_0664 NC_011353.1 693799 693933 D identified by glimmer; hypothetical protein 693799..693933 Escherichia coli O157:H7 str. EC4115 6971231 YP_002269214.1 CDS ECH74115_0665 NC_011353.1 694116 694268 D identified by match to protein family HMM PF01848; Hok/Gef family protein 694116..694268 Escherichia coli O157:H7 str. EC4115 6967560 YP_002269215.1 CDS entD NC_011353.1 694390 695019 R identified by match to protein family HMM PF01648; enterobactin synthase multienzyme complex phosphopantetheinyltransferase complement(694390..695019) Escherichia coli O157:H7 str. EC4115 6966748 YP_002269216.1 CDS fepA NC_011353.1 695185 697425 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(695185..697425) Escherichia coli O157:H7 str. EC4115 6968791 YP_002269217.1 CDS ECH74115_0668 NC_011353.1 697418 697549 D identified by glimmer; hypothetical protein 697418..697549 Escherichia coli O157:H7 str. EC4115 6967982 YP_002269218.1 CDS fes NC_011353.1 697668 698870 D identified by match to protein family HMM PF00756; enterobactin/ferric enterobactin esterase 697668..698870 Escherichia coli O157:H7 str. EC4115 6969924 YP_002269219.1 CDS ECH74115_0670 NC_011353.1 698873 699091 D identified by match to protein family HMM PF03621; mbtH-like protein 698873..699091 Escherichia coli O157:H7 str. EC4115 6966798 YP_002269220.1 CDS entF NC_011353.1 699088 702969 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 699088..702969 Escherichia coli O157:H7 str. EC4115 6972207 YP_002269221.1 CDS fepE NC_011353.1 703185 704318 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 703185..704318 Escherichia coli O157:H7 str. EC4115 6971522 YP_002269222.1 CDS fepC NC_011353.1 704315 705130 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(704315..705130) Escherichia coli O157:H7 str. EC4115 6969865 YP_002269223.1 CDS fepG NC_011353.1 705127 706119 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(705127..706119) Escherichia coli O157:H7 str. EC4115 6970624 YP_002269224.1 CDS fepD NC_011353.1 706116 707120 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(706116..707120) Escherichia coli O157:H7 str. EC4115 6971252 YP_002269225.1 CDS ECH74115_0676 NC_011353.1 707231 708481 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 707231..708481 Escherichia coli O157:H7 str. EC4115 6970798 YP_002269226.1 CDS fepB NC_011353.1 708485 709441 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(708485..709441) Escherichia coli O157:H7 str. EC4115 6969626 YP_002269227.1 CDS entC NC_011353.1 709630 710805 D identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase, entC 709630..710805 Escherichia coli O157:H7 str. EC4115 6969120 YP_002269228.1 CDS entE NC_011353.1 710815 712425 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 710815..712425 Escherichia coli O157:H7 str. EC4115 6968996 YP_002269229.1 CDS entB NC_011353.1 712439 713296 D identified by match to protein family HMM PF00550; match to protein family HMM PF00857; isochorismatase 712439..713296 Escherichia coli O157:H7 str. EC4115 6967091 YP_002269230.1 CDS entA NC_011353.1 713296 714042 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 713296..714042 Escherichia coli O157:H7 str. EC4115 6967556 YP_002269231.1 CDS ECH74115_0682 NC_011353.1 714045 714458 D identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 714045..714458 Escherichia coli O157:H7 str. EC4115 6968439 YP_002269232.1 CDS cstA NC_011353.1 714639 716744 D identified by match to protein family HMM PF02554; carbon starvation protein A 714639..716744 Escherichia coli O157:H7 str. EC4115 6968750 YP_002269233.1 CDS ECH74115_0684 NC_011353.1 716926 717123 D identified by match to protein family HMM PF04328; hypothetical protein 716926..717123 Escherichia coli O157:H7 str. EC4115 6969564 YP_002269234.1 CDS ECH74115_0685 NC_011353.1 717133 718221 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(717133..718221) Escherichia coli O157:H7 str. EC4115 6969114 YP_002269235.1 CDS ECH74115_0686 NC_011353.1 718330 719490 D catalyzes the transfer of an amino moiety; aminotransferase 718330..719490 Escherichia coli O157:H7 str. EC4115 6970102 YP_002269236.1 CDS ECH74115_0687 NC_011353.1 719491 720120 R identified by match to protein family HMM PF02195; IbrB protein complement(719491..720120) Escherichia coli O157:H7 str. EC4115 6970278 YP_002269237.1 CDS ECH74115_0688 NC_011353.1 720093 721313 R identified by match to protein family HMM PF01507; IbrA protein complement(720093..721313) Escherichia coli O157:H7 str. EC4115 6971266 YP_002269238.1 CDS ECH74115_0689 NC_011353.1 721460 722362 R identified by match to protein family HMM PF00126; LysR family transcriptional regulator complement(721460..722362) Escherichia coli O157:H7 str. EC4115 6971558 YP_002269239.1 CDS dsbG NC_011353.1 722572 723318 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(722572..723318) Escherichia coli O157:H7 str. EC4115 6967956 YP_002269240.1 CDS ahpC NC_011353.1 723690 724253 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 723690..724253 Escherichia coli O157:H7 str. EC4115 6970385 YP_002269241.1 CDS ahpF NC_011353.1 724352 725947 D identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140; alkyl hydroperoxide reductase subunit F 724352..725947 Escherichia coli O157:H7 str. EC4115 6969708 YP_002269242.1 CDS uspG NC_011353.1 726068 726496 R identified by match to protein family HMM PF00582; universal stress protein G complement(726068..726496) Escherichia coli O157:H7 str. EC4115 6971774 YP_002269243.1 CDS ECH74115_0695 NC_011353.1 726717 727955 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 726717..727955 Escherichia coli O157:H7 str. EC4115 6970855 YP_002269244.1 CDS ECH74115_0696 NC_011353.1 727959 728147 R identified by glimmer; hypothetical protein complement(727959..728147) Escherichia coli O157:H7 str. EC4115 6967159 YP_002269245.1 CDS rnk NC_011353.1 728186 728596 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(728186..728596) Escherichia coli O157:H7 str. EC4115 6969216 YP_002269246.1 CDS ECH74115_0698 NC_011353.1 728571 728732 R identified by glimmer; hypothetical protein complement(728571..728732) Escherichia coli O157:H7 str. EC4115 6968396 YP_002269247.1 CDS rna NC_011353.1 728826 729632 R identified by match to protein family HMM PF00445; ribonuclease I complement(728826..729632) Escherichia coli O157:H7 str. EC4115 6968422 YP_002269248.1 CDS ECH74115_0700 NC_011353.1 729746 731176 R identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; sodium:sulfate symporter family protein complement(729746..731176) Escherichia coli O157:H7 str. EC4115 6968287 YP_002269249.1 CDS citG NC_011353.1 731260 732132 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(731260..732132) Escherichia coli O157:H7 str. EC4115 6971875 YP_002269250.1 CDS citX NC_011353.1 732113 732664 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(732113..732664) Escherichia coli O157:H7 str. EC4115 6971900 YP_002269251.1 CDS citF NC_011353.1 732668 734200 R identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584; citrate lyase subunit alpha complement(732668..734200) Escherichia coli O157:H7 str. EC4115 6971306 YP_002269252.1 CDS citE NC_011353.1 734211 735119 R identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588; citrate (pro-3S)-lyase subunit beta complement(734211..735119) Escherichia coli O157:H7 str. EC4115 6967813 YP_002269253.1 CDS citD NC_011353.1 735116 735412 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(735116..735412) Escherichia coli O157:H7 str. EC4115 6969265 YP_002269254.1 CDS citC NC_011353.1 735427 736485 R identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125; citrate lyase synthetase complement(735427..736485) Escherichia coli O157:H7 str. EC4115 6968628 YP_002269255.1 CDS dpiB NC_011353.1 736865 738523 D identified by match to protein family HMM PF02518; sensor histidine kinase DpiB 736865..738523 Escherichia coli O157:H7 str. EC4115 6970222 YP_002269256.1 CDS dpiA NC_011353.1 738492 739172 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 738492..739172 Escherichia coli O157:H7 str. EC4115 6969601 YP_002269257.1 CDS dcuC NC_011353.1 739213 740598 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(739213..740598) Escherichia coli O157:H7 str. EC4115 6969642 YP_002269258.1 CDS pagP NC_011353.1 741187 741747 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 741187..741747 Escherichia coli O157:H7 str. EC4115 6971566 YP_002269259.1 CDS cspE NC_011353.1 741922 742131 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 741922..742131 Escherichia coli O157:H7 str. EC4115 6971399 YP_002269260.1 CDS crcB NC_011353.1 742185 742568 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(742185..742568) Escherichia coli O157:H7 str. EC4115 6970300 YP_002269261.1 CDS ECH74115_0714 NC_011353.1 742661 743449 D identified by match to protein family HMM PF00795; hydrolase 742661..743449 Escherichia coli O157:H7 str. EC4115 6969438 YP_002269262.1 CDS tatE NC_011353.1 743578 743781 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 743578..743781 Escherichia coli O157:H7 str. EC4115 6971805 YP_002269263.1 CDS lipA NC_011353.1 743882 744847 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(743882..744847) Escherichia coli O157:H7 str. EC4115 6971025 YP_002269264.1 CDS ECH74115_0717 NC_011353.1 745056 746009 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(745056..746009) Escherichia coli O157:H7 str. EC4115 6970271 YP_002269265.1 CDS lipB NC_011353.1 746269 746910 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(746269..746910) Escherichia coli O157:H7 str. EC4115 6969508 YP_002269266.1 CDS ECH74115_0719 NC_011353.1 747011 747274 R identified by match to protein family HMM PF04359; hypothetical protein complement(747011..747274) Escherichia coli O157:H7 str. EC4115 6969803 YP_002269267.1 CDS dacA NC_011353.1 747384 748595 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(747384..748595) Escherichia coli O157:H7 str. EC4115 6969389 YP_002269268.1 CDS ECH74115_0722 NC_011353.1 748618 748758 D hypothetical protein 748618..748758 Escherichia coli O157:H7 str. EC4115 6969577 YP_002269269.1 CDS rlpA NC_011353.1 748735 749823 R identified by match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413; rare lipoprotein A complement(748735..749823) Escherichia coli O157:H7 str. EC4115 6969382 YP_002269270.1 CDS mrdB NC_011353.1 749834 750946 R identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; cell wall shape-determining protein complement(749834..750946) Escherichia coli O157:H7 str. EC4115 6970379 YP_002269271.1 CDS mrdA NC_011353.1 750949 752850 R identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423; penicillin-binding protein 2 complement(750949..752850) Escherichia coli O157:H7 str. EC4115 6966945 YP_002269272.1 CDS ECH74115_0725 NC_011353.1 752881 753348 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(752881..753348) Escherichia coli O157:H7 str. EC4115 6971735 YP_002269273.1 CDS ECH74115_0726 NC_011353.1 753352 753669 R identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein complement(753352..753669) Escherichia coli O157:H7 str. EC4115 6969729 YP_002269274.1 CDS cobC NC_011353.1 753929 754540 R identified by match to protein family HMM PF00300; match to protein family HMM TIGR03162; alpha-ribazole phosphatase complement(753929..754540) Escherichia coli O157:H7 str. EC4115 6968362 YP_002269275.1 CDS nadD NC_011353.1 754564 755205 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(754564..755205) Escherichia coli O157:H7 str. EC4115 6968170 YP_002269276.1 CDS holA NC_011353.1 755207 756238 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(755207..756238) Escherichia coli O157:H7 str. EC4115 6969381 YP_002269277.1 CDS ECH74115_0730 NC_011353.1 756238 756819 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(756238..756819) Escherichia coli O157:H7 str. EC4115 6968233 YP_002269278.1 CDS leuS NC_011353.1 756834 759416 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(756834..759416) Escherichia coli O157:H7 str. EC4115 6967840 YP_002269279.1 CDS ECH74115_0732 NC_011353.1 759652 760134 D identified by match to protein family HMM PF07295; hypothetical protein 759652..760134 Escherichia coli O157:H7 str. EC4115 6967095 YP_002269280.1 CDS ECH74115_0735 NC_011353.1 761346 762053 D identified by match to protein family HMM PF06889; hypothetical protein 761346..762053 Escherichia coli O157:H7 str. EC4115 6971304 YP_002269281.1 CDS ECH74115_0736 NC_011353.1 762050 763477 D identified by match to protein family HMM PF00226; DnaJ domain-containing protein 762050..763477 Escherichia coli O157:H7 str. EC4115 6970630 YP_002269282.1 CDS ECH74115_0737 NC_011353.1 763487 764041 R identified by match to protein family HMM PF08238; hypothetical protein complement(763487..764041) Escherichia coli O157:H7 str. EC4115 6967178 YP_002269283.1 CDS ECH74115_0738 NC_011353.1 764143 764850 D identified by match to protein family HMM PF06889; hypothetical protein 764143..764850 Escherichia coli O157:H7 str. EC4115 6971555 YP_002269284.1 CDS ECH74115_0742 NC_011353.1 766264 766401 D identified by glimmer; hypothetical protein 766264..766401 Escherichia coli O157:H7 str. EC4115 6970523 YP_002269285.1 CDS hscC NC_011353.1 766358 768028 R identified by match to protein family HMM PF00012; DnaK family protein HscC complement(766358..768028) Escherichia coli O157:H7 str. EC4115 6972157 YP_002269286.1 CDS rihA NC_011353.1 768112 769047 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(768112..769047) Escherichia coli O157:H7 str. EC4115 6970087 YP_002269287.1 CDS gltL NC_011353.1 769165 769890 R identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter ATP-binding protein complement(769165..769890) Escherichia coli O157:H7 str. EC4115 6967328 YP_002269288.1 CDS gltK NC_011353.1 769890 770564 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltK complement(769890..770564) Escherichia coli O157:H7 str. EC4115 6966634 YP_002269289.1 CDS gltJ NC_011353.1 770564 771304 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltJ complement(770564..771304) Escherichia coli O157:H7 str. EC4115 6968956 YP_002269290.1 CDS gltI NC_011353.1 771474 772382 R identified by match to protein family HMM PF00497; glutamate and aspartate transporter subunit complement(771474..772382) Escherichia coli O157:H7 str. EC4115 6972300 YP_002269291.1 CDS ECH74115_0750 NC_011353.1 772672 772794 D identified by glimmer; hypothetical protein 772672..772794 Escherichia coli O157:H7 str. EC4115 6970572 YP_002269292.1 CDS lnt NC_011353.1 772779 774317 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(772779..774317) Escherichia coli O157:H7 str. EC4115 6969582 YP_002269293.1 CDS corC NC_011353.1 774342 775220 R identified by match to protein family HMM PF00571; match to protein family HMM PF03471; magnesium and cobalt efflux protein CorC complement(774342..775220) Escherichia coli O157:H7 str. EC4115 6969761 YP_002269294.1 CDS ECH74115_0752 NC_011353.1 775310 775777 R identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; metalloprotease complement(775310..775777) Escherichia coli O157:H7 str. EC4115 6969298 YP_002269295.1 CDS ECH74115_0753 NC_011353.1 775774 776814 R identified by match to protein family HMM PF02562; PhoH family protein complement(775774..776814) Escherichia coli O157:H7 str. EC4115 6968372 YP_002269296.1 CDS ECH74115_0754 NC_011353.1 776873 776992 R identified by glimmer; hypothetical protein complement(776873..776992) Escherichia coli O157:H7 str. EC4115 6967766 YP_002269297.1 CDS miaB NC_011353.1 776967 778391 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(776967..778391) Escherichia coli O157:H7 str. EC4115 6967378 YP_002269298.1 CDS ubiF NC_011353.1 778537 779712 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 778537..779712 Escherichia coli O157:H7 str. EC4115 6966607 YP_002269299.1 CDS asnB NC_011353.1 780951 782615 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(780951..782615) Escherichia coli O157:H7 str. EC4115 6972371 YP_002269300.1 CDS ECH74115_0765 NC_011353.1 782584 782748 D lipoprotein 782584..782748 Escherichia coli O157:H7 str. EC4115 6971030 YP_002269301.1 CDS nagD NC_011353.1 782872 783624 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460; UMP phosphatase complement(782872..783624) Escherichia coli O157:H7 str. EC4115 6970605 YP_002269302.1 CDS nagC NC_011353.1 783672 784892 R identified by match to protein family HMM PF00480; N-acetylglucosamine repressor complement(783672..784892) Escherichia coli O157:H7 str. EC4115 6969855 YP_002269303.1 CDS nagA NC_011353.1 784901 786049 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(784901..786049) Escherichia coli O157:H7 str. EC4115 6971577 YP_002269304.1 CDS nagB NC_011353.1 786109 786909 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(786109..786909) Escherichia coli O157:H7 str. EC4115 6966952 YP_002269305.1 CDS ECH74115_0770 NC_011353.1 786958 787083 R identified by glimmer; hypothetical protein complement(786958..787083) Escherichia coli O157:H7 str. EC4115 6967725 YP_002269306.1 CDS nagE NC_011353.1 787242 789188 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 787242..789188 Escherichia coli O157:H7 str. EC4115 6968098 YP_002269307.1 CDS ECH74115_0771 NC_011353.1 789158 789313 R identified by glimmer; hypothetical protein complement(789158..789313) Escherichia coli O157:H7 str. EC4115 6969035 YP_002269308.1 CDS glnS NC_011353.1 789391 791055 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 789391..791055 Escherichia coli O157:H7 str. EC4115 6968729 YP_002269309.1 CDS ECH74115_0774 NC_011353.1 791128 791322 R enterobactin synthase multienzyme complex phosphopantetheinyltransferase complement(791128..791322) Escherichia coli O157:H7 str. EC4115 6970017 YP_002269310.1 CDS ECH74115_0777 NC_011353.1 793089 793415 D lipoprotein 793089..793415 Escherichia coli O157:H7 str. EC4115 6971584 YP_002269311.1 CDS fur NC_011353.1 793499 793945 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(793499..793945) Escherichia coli O157:H7 str. EC4115 6968854 YP_002269312.1 CDS fldA NC_011353.1 794234 794764 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(794234..794764) Escherichia coli O157:H7 str. EC4115 6970295 YP_002269313.1 CDS ECH74115_0780 NC_011353.1 794904 795266 R identified by match to protein family HMM PF01402; LexA regulated protein complement(794904..795266) Escherichia coli O157:H7 str. EC4115 6971296 YP_002269314.1 CDS ybfF NC_011353.1 795337 796101 R identified by match to protein family HMM PF00561; match to protein family HMM PF07819; hypothetical protein complement(795337..796101) Escherichia coli O157:H7 str. EC4115 6971963 YP_002269315.1 CDS seqA NC_011353.1 796286 796831 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 796286..796831 Escherichia coli O157:H7 str. EC4115 6967172 YP_002269316.1 CDS pgm NC_011353.1 796857 798497 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 796857..798497 Escherichia coli O157:H7 str. EC4115 6967380 YP_002269317.1 CDS potE NC_011353.1 798554 799873 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(798554..799873) Escherichia coli O157:H7 str. EC4115 6969220 YP_002269318.1 CDS speF NC_011353.1 799870 802077 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase complement(799870..802077) Escherichia coli O157:H7 str. EC4115 6968971 YP_002269319.1 CDS ECH74115_0786 NC_011353.1 802462 802596 R identified by glimmer; hypothetical protein complement(802462..802596) Escherichia coli O157:H7 str. EC4115 6969456 YP_002269320.1 CDS kdpE NC_011353.1 802758 803435 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(802758..803435) Escherichia coli O157:H7 str. EC4115 6971259 YP_002269321.1 CDS kdpD NC_011353.1 803432 806116 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(803432..806116) Escherichia coli O157:H7 str. EC4115 6969288 YP_002269322.1 CDS kdpC NC_011353.1 806109 806681 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(806109..806681) Escherichia coli O157:H7 str. EC4115 6968537 YP_002269323.1 CDS kdpB NC_011353.1 806690 808738 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(806690..808738) Escherichia coli O157:H7 str. EC4115 6968356 YP_002269324.1 CDS kdpA NC_011353.1 808761 810434 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(808761..810434) Escherichia coli O157:H7 str. EC4115 6967883 YP_002269325.1 CDS ECH74115_0792 NC_011353.1 810836 811042 D hypothetical protein 810836..811042 Escherichia coli O157:H7 str. EC4115 6966818 YP_002269326.1 CDS ECH74115_0793 NC_011353.1 811043 811225 D identified by glimmer; hypothetical protein 811043..811225 Escherichia coli O157:H7 str. EC4115 6972068 YP_002269327.1 CDS ECH74115_0794 NC_011353.1 811282 815481 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS repeat protein 811282..815481 Escherichia coli O157:H7 str. EC4115 6970052 YP_002269328.1 CDS ECH74115_0795 NC_011353.1 815478 816047 D identified by glimmer; hypothetical protein 815478..816047 Escherichia coli O157:H7 str. EC4115 6969413 YP_002269329.1 CDS ECH74115_0796 NC_011353.1 817634 818770 D identified by match to protein family HMM PF01609; ISEc4, transposase 817634..818770 Escherichia coli O157:H7 str. EC4115 6968477 YP_002269330.1 CDS ECH74115_0797 NC_011353.1 818919 819428 D identified by match to protein family HMM PF08349; hypothetical protein 818919..819428 Escherichia coli O157:H7 str. EC4115 6967814 YP_002269331.1 CDS phrB NC_011353.1 819425 820843 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 819425..820843 Escherichia coli O157:H7 str. EC4115 6966712 YP_002269332.1 CDS ECH74115_0799 NC_011353.1 820993 822474 R identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter complement(820993..822474) Escherichia coli O157:H7 str. EC4115 6968894 YP_002269333.1 CDS ECH74115_0800 NC_011353.1 822745 823488 D identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hydrolase-oxidase 822745..823488 Escherichia coli O157:H7 str. EC4115 6969815 YP_002269334.1 CDS ECH74115_0801 NC_011353.1 823511 824167 D identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370; allophanate hydrolase, subunit 1 823511..824167 Escherichia coli O157:H7 str. EC4115 6972083 YP_002269335.1 CDS ECH74115_0802 NC_011353.1 824161 825093 D identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724; allophanate hydrolase subunit 2 824161..825093 Escherichia coli O157:H7 str. EC4115 6971462 YP_002269336.1 CDS ECH74115_0803 NC_011353.1 825083 825817 D identified by match to protein family HMM PF03746; LamB/YcsF family protein 825083..825817 Escherichia coli O157:H7 str. EC4115 6967318 YP_002269337.1 CDS abrB NC_011353.1 826640 827686 R identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082; protein AbrB complement(826640..827686) Escherichia coli O157:H7 str. EC4115 6968938 YP_002269338.1 CDS ECH74115_0806 NC_011353.1 827835 828896 R hypothetical protein complement(827835..828896) Escherichia coli O157:H7 str. EC4115 6966734 YP_002269339.1 CDS ECH74115_0807 NC_011353.1 828893 829624 R identified by match to protein family HMM PF00345; periplasmic pilus chaperone family protein complement(828893..829624) Escherichia coli O157:H7 str. EC4115 6970492 YP_002269340.1 CDS ECH74115_0808 NC_011353.1 829639 832089 R identified by match to protein family HMM PF00577; fimbrial usher protein complement(829639..832089) Escherichia coli O157:H7 str. EC4115 6969852 YP_002269341.1 CDS ECH74115_0809 NC_011353.1 832148 832714 R identified by match to protein family HMM PF00419; fimbrial protein complement(832148..832714) Escherichia coli O157:H7 str. EC4115 6970496 YP_002269342.1 CDS gltA NC_011353.1 833101 834384 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(833101..834384) Escherichia coli O157:H7 str. EC4115 6971997 YP_002269343.1 CDS sdhC NC_011353.1 835078 835482 D succinate dehydrogenase cytochrome b556 large membrane subunit 835078..835482 Escherichia coli O157:H7 str. EC4115 6966621 YP_002269344.1 CDS ECH74115_0812 NC_011353.1 835135 835272 R hypothetical protein complement(835135..835272) Escherichia coli O157:H7 str. EC4115 6968686 YP_002269345.1 CDS sdhD NC_011353.1 835476 835823 D identified by match to protein family HMM TIGR02968; succinate dehydrogenase cytochrome b556 small membrane subunit 835476..835823 Escherichia coli O157:H7 str. EC4115 6967423 YP_002269346.1 CDS sdhA NC_011353.1 835823 837589 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 835823..837589 Escherichia coli O157:H7 str. EC4115 6969620 YP_002269347.1 CDS sdhB NC_011353.1 837605 838321 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 837605..838321 Escherichia coli O157:H7 str. EC4115 6970437 YP_002269348.1 CDS ECH74115_0817 NC_011353.1 838355 838486 R hypothetical protein complement(838355..838486) Escherichia coli O157:H7 str. EC4115 6971227 YP_002269349.1 CDS sucA NC_011353.1 838622 841423 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 838622..841423 Escherichia coli O157:H7 str. EC4115 6969912 YP_002269350.1 CDS sucB NC_011353.1 841438 842655 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 841438..842655 Escherichia coli O157:H7 str. EC4115 6970520 YP_002269351.1 CDS sucC NC_011353.1 842749 843915 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 842749..843915 Escherichia coli O157:H7 str. EC4115 6968213 YP_002269352.1 CDS sucD NC_011353.1 843915 844784 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 843915..844784 Escherichia coli O157:H7 str. EC4115 6968400 YP_002269353.1 CDS ECH74115_0822 NC_011353.1 845034 845180 D hypothetical protein 845034..845180 Escherichia coli O157:H7 str. EC4115 6966622 YP_002269354.1 CDS ECH74115_0823 NC_011353.1 845451 846356 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 845451..846356 Escherichia coli O157:H7 str. EC4115 6967595 YP_002269355.1 CDS cobO NC_011353.1 846390 846992 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(846390..846992) Escherichia coli O157:H7 str. EC4115 6967331 YP_002269356.1 CDS ECH74115_0825 NC_011353.1 847002 848654 R identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; hydro-lyase, Fe-S type, tartrate/fumarate family complement(847002..848654) Escherichia coli O157:H7 str. EC4115 6970843 YP_002269357.1 CDS ECH74115_0826 NC_011353.1 848762 850042 R identified by match to protein family HMM PF00375; transporter dicarboxylate/amino acid:cation family complement(848762..850042) Escherichia coli O157:H7 str. EC4115 6972161 YP_002269358.1 CDS ECH74115_0827 NC_011353.1 850203 850520 R hypothetical protein complement(850203..850520) Escherichia coli O157:H7 str. EC4115 6969937 YP_002269359.1 CDS ECH74115_0828 NC_011353.1 850517 851887 R hypothetical protein complement(850517..851887) Escherichia coli O157:H7 str. EC4115 6969183 YP_002269360.1 CDS ECH74115_0829 NC_011353.1 851891 853132 R identified by match to protein family HMM PF05034; match to protein family HMM PF07476; match to protein family HMM TIGR01502; methylaspartate ammonia-lyase complement(851891..853132) Escherichia coli O157:H7 str. EC4115 6966788 YP_002269361.1 CDS mutE NC_011353.1 853132 854577 R identified by match to protein family HMM PF06368; match to protein family HMM TIGR01503; methylaspartate mutase subunit E complement(853132..854577) Escherichia coli O157:H7 str. EC4115 6967869 YP_002269362.1 CDS ECH74115_0831 NC_011353.1 854596 855984 R identified by match to protein family HMM TIGR01319; glutamate mutase mutL complement(854596..855984) Escherichia coli O157:H7 str. EC4115 6971187 YP_002269363.1 CDS mamA NC_011353.1 855984 856433 R converts methylaspartate to L-glutamate; methylaspartate mutase subunit S complement(855984..856433) Escherichia coli O157:H7 str. EC4115 6970894 YP_002269364.1 CDS ECH74115_0833 NC_011353.1 856981 857280 R identified by glimmer; hypothetical protein complement(856981..857280) Escherichia coli O157:H7 str. EC4115 6971705 YP_002269365.1 CDS ECH74115_0834 NC_011353.1 857485 858312 R identified by glimmer; hypothetical protein complement(857485..858312) Escherichia coli O157:H7 str. EC4115 6969479 YP_002269366.1 CDS cydA NC_011353.1 859235 860803 D identified by match to protein family HMM PF01654; cytochrome d ubiquinol oxidase, subunit I 859235..860803 Escherichia coli O157:H7 str. EC4115 6970114 YP_002269367.1 CDS cydB1 NC_011353.1 860819 861958 D identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome d ubiquinol oxidase, subunit II 860819..861958 Escherichia coli O157:H7 str. EC4115 6968350 YP_002269368.1 CDS ECH74115_0837 NC_011353.1 861973 862086 D identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106; cyd operon protein YbgT 861973..862086 Escherichia coli O157:H7 str. EC4115 6969242 YP_002269369.1 CDS ECH74115_0838 NC_011353.1 862179 862379 D identified by match to protein family HMM TIGR02112; hypothetical protein 862179..862379 Escherichia coli O157:H7 str. EC4115 6968886 YP_002269370.1 CDS ybgC NC_011353.1 862529 862933 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 862529..862933 Escherichia coli O157:H7 str. EC4115 6967998 YP_002269371.1 CDS tolQ NC_011353.1 862930 863622 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 862930..863622 Escherichia coli O157:H7 str. EC4115 6970769 YP_002269372.1 CDS tolR NC_011353.1 863626 864054 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 863626..864054 Escherichia coli O157:H7 str. EC4115 6969942 YP_002269373.1 CDS tolA NC_011353.1 864119 865393 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 864119..865393 Escherichia coli O157:H7 str. EC4115 6972034 YP_002269374.1 CDS tolB NC_011353.1 865526 866818 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 865526..866818 Escherichia coli O157:H7 str. EC4115 6971245 YP_002269375.1 CDS pal NC_011353.1 866853 867374 D identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802; peptidoglycan-associated outer membrane lipoprotein 866853..867374 Escherichia coli O157:H7 str. EC4115 6971020 YP_002269376.1 CDS ygbF NC_011353.1 867384 868175 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 867384..868175 Escherichia coli O157:H7 str. EC4115 6967330 YP_002269377.1 CDS nadA NC_011353.1 869319 870353 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 869319..870353 Escherichia coli O157:H7 str. EC4115 6972398 YP_002269378.1 CDS pnuC NC_011353.1 870391 871110 D identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter PnuC 870391..871110 Escherichia coli O157:H7 str. EC4115 6969373 YP_002269379.1 CDS zitB NC_011353.1 871107 872048 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(871107..872048) Escherichia coli O157:H7 str. EC4115 6967247 YP_002269380.1 CDS ECH74115_0855 NC_011353.1 872162 872542 R hypothetical protein complement(872162..872542) Escherichia coli O157:H7 str. EC4115 6968294 YP_002269381.1 CDS aroG NC_011353.1 872858 873910 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 872858..873910 Escherichia coli O157:H7 str. EC4115 6966646 YP_002269382.1 CDS gpmA NC_011353.1 874076 874828 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(874076..874828) Escherichia coli O157:H7 str. EC4115 6971780 YP_002269383.1 CDS ECH74115_0858 NC_011353.1 874902 875030 R identified by glimmer; hypothetical protein complement(874902..875030) Escherichia coli O157:H7 str. EC4115 6972064 YP_002269384.1 CDS galM NC_011353.1 875030 876070 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(875030..876070) Escherichia coli O157:H7 str. EC4115 6970158 YP_002269385.1 CDS galK NC_011353.1 876064 877212 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(876064..877212) Escherichia coli O157:H7 str. EC4115 6969669 YP_002269386.1 CDS galT NC_011353.1 877216 878262 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(877216..878262) Escherichia coli O157:H7 str. EC4115 6970055 YP_002269387.1 CDS galE NC_011353.1 878272 879288 R identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-galactose-4-epimerase complement(878272..879288) Escherichia coli O157:H7 str. EC4115 6968825 YP_002269388.1 CDS modF NC_011353.1 879550 881022 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(879550..881022) Escherichia coli O157:H7 str. EC4115 6968397 YP_002269389.1 CDS modE NC_011353.1 881090 881878 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(881090..881878) Escherichia coli O157:H7 str. EC4115 6966809 YP_002269390.1 CDS ECH74115_0865 NC_011353.1 882007 882156 D hypothetical protein 882007..882156 Escherichia coli O157:H7 str. EC4115 6972007 YP_002269391.1 CDS modA NC_011353.1 882323 883096 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 882323..883096 Escherichia coli O157:H7 str. EC4115 6971210 YP_002269392.1 CDS modB NC_011353.1 883096 883785 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 883096..883785 Escherichia coli O157:H7 str. EC4115 6970690 YP_002269393.1 CDS modC NC_011353.1 883788 884846 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 883788..884846 Escherichia coli O157:H7 str. EC4115 6970058 YP_002269394.1 CDS ybhA NC_011353.1 884847 885767 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(884847..885767) Escherichia coli O157:H7 str. EC4115 6969720 YP_002269395.1 CDS pgl NC_011353.1 885820 886815 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 885820..886815 Escherichia coli O157:H7 str. EC4115 6968682 YP_002269396.1 CDS ECH74115_0871 NC_011353.1 886856 887809 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(886856..887809) Escherichia coli O157:H7 str. EC4115 6968387 YP_002269397.1 CDS ECH74115_0872 NC_011353.1 887791 887907 D identified by glimmer; hypothetical protein 887791..887907 Escherichia coli O157:H7 str. EC4115 6967531 YP_002269398.1 CDS ECH74115_0873 NC_011353.1 887993 889045 D identified by match to protein family HMM PF04303; hypothetical protein 887993..889045 Escherichia coli O157:H7 str. EC4115 6967211 YP_002269399.1 CDS ECH74115_0874 NC_011353.1 889121 890554 D identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785; anion transporter 889121..890554 Escherichia coli O157:H7 str. EC4115 6972120 YP_002269400.1 CDS ECH74115_0875 NC_011353.1 890737 892998 D identified by match to protein family HMM PF00330; hypothetical protein 890737..892998 Escherichia coli O157:H7 str. EC4115 6968892 YP_002269401.1 CDS ECH74115_0876 NC_011353.1 893139 894422 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase complement(893139..894422) Escherichia coli O157:H7 str. EC4115 6970494 YP_002269402.1 CDS ECH74115_0877 NC_011353.1 894557 895627 R identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM PF09003; phage integrase family protein complement(894557..895627) Escherichia coli O157:H7 str. EC4115 6968905 YP_002269403.1 CDS ECH74115_0878 NC_011353.1 895875 896045 D identified by glimmer; hypothetical protein 895875..896045 Escherichia coli O157:H7 str. EC4115 6968291 YP_002269404.1 CDS ECH74115_0879 NC_011353.1 896332 896454 D hypothetical protein 896332..896454 Escherichia coli O157:H7 str. EC4115 6970519 YP_002269405.1 CDS ECH74115_0880 NC_011353.1 896726 896875 D hypothetical protein 896726..896875 Escherichia coli O157:H7 str. EC4115 6969914 YP_002269406.1 CDS ECH74115_0881 NC_011353.1 897406 897621 R hypothetical protein complement(897406..897621) Escherichia coli O157:H7 str. EC4115 6972159 YP_002269407.1 CDS ECH74115_0882 NC_011353.1 897698 897889 R identified by match to protein family HMM PF07131; hypothetical protein complement(897698..897889) Escherichia coli O157:H7 str. EC4115 6971536 YP_002269408.1 CDS exo NC_011353.1 898041 898721 R identified by match to protein family HMM PF09588; exonuclease complement(898041..898721) Escherichia coli O157:H7 str. EC4115 6968013 YP_002269409.1 CDS ECH74115_0884 NC_011353.1 898718 899365 R identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; recombination protein bet complement(898718..899365) Escherichia coli O157:H7 str. EC4115 6967796 YP_002269410.1 CDS ECH74115_0885 NC_011353.1 899758 900381 D identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein 899758..900381 Escherichia coli O157:H7 str. EC4115 6968588 YP_002269411.1 CDS ECH74115_0886 NC_011353.1 900378 901043 D identified by match to protein family HMM PF00149; serine/threonine-protein phosphatase 1 900378..901043 Escherichia coli O157:H7 str. EC4115 6969168 YP_002269412.1 CDS ECH74115_0887 NC_011353.1 901255 902214 R outer membrane protein complement(901255..902214) Escherichia coli O157:H7 str. EC4115 6971240 YP_002269413.1 CDS ECH74115_0888 NC_011353.1 902689 903378 D identified by match to protein family HMM PF06323; anti-termination protein 902689..903378 Escherichia coli O157:H7 str. EC4115 6972057 YP_002269414.1 CDS ECH74115_0889 NC_011353.1 903589 904305 D hypothetical protein 903589..904305 Escherichia coli O157:H7 str. EC4115 6967434 YP_002269415.1 CDS ECH74115_0890 NC_011353.1 904391 904549 D hypothetical protein 904391..904549 Escherichia coli O157:H7 str. EC4115 6970882 YP_002269416.1 CDS ECH74115_0892 NC_011353.1 905386 905883 D identified by match to protein family HMM PF00959; phage lysozyme 905386..905883 Escherichia coli O157:H7 str. EC4115 6967108 YP_002269417.1 CDS ECH74115_0893 NC_011353.1 905880 906347 D identified by match to protein family HMM PF03245; bacteriophage lysis protein 905880..906347 Escherichia coli O157:H7 str. EC4115 6970812 YP_002269418.1 CDS ECH74115_0894 NC_011353.1 906335 906487 D hypothetical protein 906335..906487 Escherichia coli O157:H7 str. EC4115 6971685 YP_002269419.1 CDS ECH74115_0895 NC_011353.1 907162 907653 D identified by match to protein family HMM PF07278; bacteriophage DNA packaging protein; terminase, small subunit 907162..907653 Escherichia coli O157:H7 str. EC4115 6971940 YP_002269420.1 CDS ECH74115_0896 NC_011353.1 907653 909755 D identified by match to protein family HMM PF05876; phage terminase large subunit 907653..909755 Escherichia coli O157:H7 str. EC4115 6970430 YP_002269421.1 CDS ECH74115_0897 NC_011353.1 909752 909964 D hypothetical protein 909752..909964 Escherichia coli O157:H7 str. EC4115 6971652 YP_002269422.1 CDS clpP NC_011353.1 911487 913445 D identified by match to protein family HMM PF00574; Clp protease domain-containing protein 911487..913445 Escherichia coli O157:H7 str. EC4115 6967957 YP_002269423.1 CDS ECH74115_0901 NC_011353.1 913532 913855 D hypothetical protein 913532..913855 Escherichia coli O157:H7 str. EC4115 6968500 YP_002269424.1 CDS ECH74115_0902 NC_011353.1 913848 914123 D hypothetical protein 913848..914123 Escherichia coli O157:H7 str. EC4115 6968721 YP_002269425.1 CDS ECH74115_0903 NC_011353.1 914135 914713 D identified by match to protein family HMM PF06763; prophage minor tail protein Z 914135..914713 Escherichia coli O157:H7 str. EC4115 6967613 YP_002269426.1 CDS ECH74115_0904 NC_011353.1 914710 915111 D identified by match to protein family HMM PF06141; phage minor tail protein U 914710..915111 Escherichia coli O157:H7 str. EC4115 6971370 YP_002269427.1 CDS ECH74115_0905 NC_011353.1 915122 915865 D identified by match to protein family HMM PF02368; gp13 915122..915865 Escherichia coli O157:H7 str. EC4115 6966840 YP_002269428.1 CDS ECH74115_0906 NC_011353.1 915926 916312 D identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 915926..916312 Escherichia coli O157:H7 str. EC4115 6966949 YP_002269429.1 CDS ECH74115_0907 NC_011353.1 916333 916650 D identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 916333..916650 Escherichia coli O157:H7 str. EC4115 6971341 YP_002269430.1 CDS ECH74115_0908 NC_011353.1 916622 919687 D identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 916622..919687 Escherichia coli O157:H7 str. EC4115 6966762 YP_002269431.1 CDS ECH74115_0909 NC_011353.1 919687 920016 D identified by match to protein family HMM PF05939; phage minor tail protein 919687..920016 Escherichia coli O157:H7 str. EC4115 6967565 YP_002269432.1 CDS ECH74115_0910 NC_011353.1 920026 920724 D identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 920026..920724 Escherichia coli O157:H7 str. EC4115 6968020 YP_002269433.1 CDS ECH74115_0911 NC_011353.1 920730 921473 D identified by match to protein family HMM PF00877; tail assembly protein 920730..921473 Escherichia coli O157:H7 str. EC4115 6968062 YP_002269434.1 CDS ECH74115_0912 NC_011353.1 921506 922018 D identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 921506..922018 Escherichia coli O157:H7 str. EC4115 6968845 YP_002269435.1 CDS ECH74115_0913 NC_011353.1 922079 925492 D identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 922079..925492 Escherichia coli O157:H7 str. EC4115 6969975 YP_002269436.1 CDS ECH74115_0914 NC_011353.1 925563 926162 D identified by match to protein family HMM PF06316; Ail/Lom family protein 925563..926162 Escherichia coli O157:H7 str. EC4115 6970656 YP_002269437.1 CDS ECH74115_0915 NC_011353.1 926222 927538 D identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 926222..927538 Escherichia coli O157:H7 str. EC4115 6966921 YP_002269438.1 CDS ECH74115_0916 NC_011353.1 927540 927809 D identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 927540..927809 Escherichia coli O157:H7 str. EC4115 6969150 YP_002269439.1 CDS ECH74115_0917 NC_011353.1 927986 928966 D non-LEE-encoded effector NleB 927986..928966 Escherichia coli O157:H7 str. EC4115 6971562 YP_002269440.1 CDS ECH74115_0918 NC_011353.1 929027 930019 D non-LEE encoded type III effector C 929027..930019 Escherichia coli O157:H7 str. EC4115 6971448 YP_002269441.1 CDS ECH74115_0919 NC_011353.1 930847 931728 D non-LEE-encoded effector NleH 930847..931728 Escherichia coli O157:H7 str. EC4115 6970644 YP_002269442.1 CDS ECH74115_0921 NC_011353.1 933164 933640 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(933164..933640) Escherichia coli O157:H7 str. EC4115 6968377 YP_002269443.1 CDS bioA NC_011353.1 933699 935099 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(933699..935099) Escherichia coli O157:H7 str. EC4115 6968230 YP_002269444.1 CDS bioB NC_011353.1 935075 936115 D identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthase 935075..936115 Escherichia coli O157:H7 str. EC4115 6967435 YP_002269445.1 CDS bioF NC_011353.1 936112 937266 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 936112..937266 Escherichia coli O157:H7 str. EC4115 6972245 YP_002269446.1 CDS bioC NC_011353.1 937253 938008 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 937253..938008 Escherichia coli O157:H7 str. EC4115 6969964 YP_002269447.1 CDS bioD NC_011353.1 938001 938678 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 938001..938678 Escherichia coli O157:H7 str. EC4115 6970801 YP_002269448.1 CDS uvrB NC_011353.1 939257 941278 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 939257..941278 Escherichia coli O157:H7 str. EC4115 6968958 YP_002269449.1 CDS ECH74115_0928 NC_011353.1 941469 942377 R identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein complement(941469..942377) Escherichia coli O157:H7 str. EC4115 6969392 YP_002269450.1 CDS moaA NC_011353.1 942774 943763 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 942774..943763 Escherichia coli O157:H7 str. EC4115 6968351 YP_002269451.1 CDS moaB NC_011353.1 943785 944297 D identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667; molybdenum cofactor biosynthesis protein B 943785..944297 Escherichia coli O157:H7 str. EC4115 6969166 YP_002269452.1 CDS moaC NC_011353.1 944300 944785 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 944300..944785 Escherichia coli O157:H7 str. EC4115 6972173 YP_002269453.1 CDS moaD NC_011353.1 944778 945023 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 944778..945023 Escherichia coli O157:H7 str. EC4115 6966893 YP_002269454.1 CDS moaE NC_011353.1 945025 945477 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 945025..945477 Escherichia coli O157:H7 str. EC4115 6970248 YP_002269455.1 CDS ECH74115_0934 NC_011353.1 945613 946317 D identified by match to protein family HMM PF01027; hypothetical protein 945613..946317 Escherichia coli O157:H7 str. EC4115 6968525 YP_002269456.1 CDS ECH74115_0935 NC_011353.1 946525 947238 D identified by match to protein family HMM PF01027; hypothetical protein 946525..947238 Escherichia coli O157:H7 str. EC4115 6971772 YP_002269457.1 CDS ECH74115_0936 NC_011353.1 947274 948230 R hypothetical protein complement(947274..948230) Escherichia coli O157:H7 str. EC4115 6969768 YP_002269458.1 CDS ECH74115_0937 NC_011353.1 948230 949471 R identified by match to protein family HMM PF00614; cardiolipin synthase 2 complement(948230..949471) Escherichia coli O157:H7 str. EC4115 6972181 YP_002269459.1 CDS ECH74115_0938 NC_011353.1 949468 950229 R identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family protein complement(949468..950229) Escherichia coli O157:H7 str. EC4115 6971612 YP_002269460.1 CDS ECH74115_0940 NC_011353.1 950362 950772 D hypothetical protein 950362..950772 Escherichia coli O157:H7 str. EC4115 6967708 YP_002269461.1 CDS ECH74115_0939 NC_011353.1 950734 951840 R identified by match to protein family HMM PF01061; ABC-2 type transporter permease complement(950734..951840) Escherichia coli O157:H7 str. EC4115 6968236 YP_002269462.1 CDS ECH74115_0941 NC_011353.1 951851 952984 R identified by match to protein family HMM PF01061; ABC-2 type transporter permease complement(951851..952984) Escherichia coli O157:H7 str. EC4115 6971365 YP_002269463.1 CDS ECH74115_0942 NC_011353.1 952977 954713 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(952977..954713) Escherichia coli O157:H7 str. EC4115 6968925 YP_002269464.1 CDS ECH74115_0943 NC_011353.1 954706 955701 R identified by match to protein family HMM PF00529; hypothetical protein complement(954706..955701) Escherichia coli O157:H7 str. EC4115 6969862 YP_002269465.1 CDS ECH74115_0944 NC_011353.1 955704 956375 R identified by match to protein family HMM PF00440; match to protein family HMM PF09209; DNA-binding transcriptional regulator complement(955704..956375) Escherichia coli O157:H7 str. EC4115 6969028 YP_002269466.1 CDS ECH74115_0945 NC_011353.1 956604 957971 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 956604..957971 Escherichia coli O157:H7 str. EC4115 6971464 YP_002269467.1 CDS ECH74115_0946 NC_011353.1 958123 958266 D identified by glimmer; hypothetical protein 958123..958266 Escherichia coli O157:H7 str. EC4115 6967261 YP_002269468.1 CDS ECH74115_0947 NC_011353.1 958579 960591 D identified by glimmer; hypothetical protein 958579..960591 Escherichia coli O157:H7 str. EC4115 6971396 YP_002269469.1 CDS dinG NC_011353.1 960737 963025 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 960737..963025 Escherichia coli O157:H7 str. EC4115 6967338 YP_002269470.1 CDS ECH74115_0949 NC_011353.1 963053 964015 D identified by match to protein family HMM PF02885; glycosyl transferase family protein 963053..964015 Escherichia coli O157:H7 str. EC4115 6969789 YP_002269471.1 CDS ECH74115_0950 NC_011353.1 964156 965241 D identified by match to protein family HMM PF02615; hypothetical protein 964156..965241 Escherichia coli O157:H7 str. EC4115 6972208 YP_002269472.1 CDS ECH74115_0951 NC_011353.1 965470 965730 R identified by match to protein family HMM PF07338; hypothetical protein complement(965470..965730) Escherichia coli O157:H7 str. EC4115 6968891 YP_002269473.1 CDS ECH74115_0952 NC_011353.1 965995 966261 R identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; hypothetical protein complement(965995..966261) Escherichia coli O157:H7 str. EC4115 6968265 YP_002269474.1 CDS ECH74115_0953 NC_011353.1 966335 967021 R identified by match to protein family HMM PF03171; hydroxylase complement(966335..967021) Escherichia coli O157:H7 str. EC4115 6967283 YP_002269475.1 CDS fiu NC_011353.1 967063 969345 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(967063..969345) Escherichia coli O157:H7 str. EC4115 6969504 YP_002269476.1 CDS ECH74115_0955 NC_011353.1 969610 969870 R identified by match to protein family HMM PF07338; hypothetical protein complement(969610..969870) Escherichia coli O157:H7 str. EC4115 6968053 YP_002269477.1 CDS ECH74115_0957 NC_011353.1 970146 971072 D identified by match to protein family HMM PF05971; SAM-dependent methyltransferase 970146..971072 Escherichia coli O157:H7 str. EC4115 6968667 YP_002269478.1 CDS ECH74115_0956 NC_011353.1 971069 973294 R identified by match to protein family HMM PF00924; hypothetical protein complement(971069..973294) Escherichia coli O157:H7 str. EC4115 6967493 YP_002269479.1 CDS glnQ NC_011353.1 973411 974133 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(973411..974133) Escherichia coli O157:H7 str. EC4115 6966830 YP_002269480.1 CDS glnP NC_011353.1 974130 974789 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(974130..974789) Escherichia coli O157:H7 str. EC4115 6970038 YP_002269481.1 CDS glnH NC_011353.1 974927 975673 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(974927..975673) Escherichia coli O157:H7 str. EC4115 6970668 YP_002269482.1 CDS dps NC_011353.1 976077 976580 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(976077..976580) Escherichia coli O157:H7 str. EC4115 6968105 YP_002269483.1 CDS rhtA NC_011353.1 976879 977778 R identified by match to protein family HMM PF00892; threonine and homoserine efflux system complement(976879..977778) Escherichia coli O157:H7 str. EC4115 6968731 YP_002269484.1 CDS ompX NC_011353.1 978119 978634 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 978119..978634 Escherichia coli O157:H7 str. EC4115 6967312 YP_002269485.1 CDS ECH74115_0964 NC_011353.1 978683 980266 R identified by match to protein family HMM PF00884; sulfatase family protein complement(978683..980266) Escherichia coli O157:H7 str. EC4115 6972162 YP_002269486.1 CDS mntR NC_011353.1 980852 981319 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 980852..981319 Escherichia coli O157:H7 str. EC4115 6970587 YP_002269487.1 CDS ECH74115_0967 NC_011353.1 981316 982434 D identified by match to protein family HMM PF03600; citrate transporter family protein 981316..982434 Escherichia coli O157:H7 str. EC4115 6970213 YP_002269488.1 CDS ybiS NC_011353.1 982492 983406 R identified by match to protein family HMM PF03734; hypothetical protein complement(982492..983406) Escherichia coli O157:H7 str. EC4115 6970856 YP_002269489.1 CDS ECH74115_0969 NC_011353.1 983631 985223 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 983631..985223 Escherichia coli O157:H7 str. EC4115 6968895 YP_002269490.1 CDS ECH74115_0970 NC_011353.1 985391 986656 R identified by match to protein family HMM PF07350; hypothetical protein complement(985391..986656) Escherichia coli O157:H7 str. EC4115 6969905 YP_002269491.1 CDS supH NC_011353.1 986808 987623 R identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; sugar phosphatase SupH complement(986808..987623) Escherichia coli O157:H7 str. EC4115 6968462 YP_002269492.1 CDS ECH74115_0974 NC_011353.1 990206 991105 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating protein complement(990206..991105) Escherichia coli O157:H7 str. EC4115 6967099 YP_002269493.1 CDS fsaA NC_011353.1 991236 991898 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 991236..991898 Escherichia coli O157:H7 str. EC4115 6971586 YP_002269494.1 CDS moeB NC_011353.1 992077 992826 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(992077..992826) Escherichia coli O157:H7 str. EC4115 6970942 YP_002269495.1 CDS moeA NC_011353.1 992826 994061 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(992826..994061) Escherichia coli O157:H7 str. EC4115 6970451 YP_002269496.1 CDS gsiA NC_011353.1 995199 997088 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 995199..997088 Escherichia coli O157:H7 str. EC4115 6967896 YP_002269497.1 CDS gsiB NC_011353.1 997108 998646 D identified by match to protein family HMM PF00496; glutathione ABC transporter periplasmic glutathione-binding protein GsiB 997108..998646 Escherichia coli O157:H7 str. EC4115 6971547 YP_002269498.1 CDS gsiC NC_011353.1 998664 999584 D identified by match to protein family HMM PF00528; glutathione ABC transporter permease GsiC 998664..999584 Escherichia coli O157:H7 str. EC4115 6970879 YP_002269499.1 CDS gsiD NC_011353.1 999587 1000498 D identified by match to protein family HMM PF00528; glutathione ABC transporter permease GsiD 999587..1000498 Escherichia coli O157:H7 str. EC4115 6971080 YP_002269500.1 CDS ECH74115_0984 NC_011353.1 1000676 1003024 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 1000676..1003024 Escherichia coli O157:H7 str. EC4115 6969842 YP_002269501.1 CDS ECH74115_0985 NC_011353.1 1003119 1004360 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1003119..1004360 Escherichia coli O157:H7 str. EC4115 6969681 YP_002269502.1 CDS ECH74115_0986 NC_011353.1 1004430 1004759 R identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein complement(1004430..1004759) Escherichia coli O157:H7 str. EC4115 6971348 YP_002269503.1 CDS ECH74115_0987 NC_011353.1 1004749 1005135 R identified by match to protein family HMM PF06296; hypothetical protein complement(1004749..1005135) Escherichia coli O157:H7 str. EC4115 6966690 YP_002269504.1 CDS rimO NC_011353.1 1005361 1006686 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; 30S ribosomal protein S12 methylthiotransferase complement(1005361..1006686) Escherichia coli O157:H7 str. EC4115 6967290 YP_002269505.1 CDS bssR NC_011353.1 1006899 1007282 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1006899..1007282 Escherichia coli O157:H7 str. EC4115 6968246 YP_002269506.1 CDS ECH74115_0991 NC_011353.1 1007393 1008508 D identified by match to protein family HMM PF07995; glucose / sorbosone dehydrogenase 1007393..1008508 Escherichia coli O157:H7 str. EC4115 6969011 YP_002269507.1 CDS ECH74115_0990 NC_011353.1 1008505 1009131 R identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase family protein complement(1008505..1009131) Escherichia coli O157:H7 str. EC4115 6970545 YP_002269508.1 CDS dacC NC_011353.1 1009368 1010579 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1009368..1010579 Escherichia coli O157:H7 str. EC4115 6969894 YP_002269509.1 CDS deoR NC_011353.1 1010626 1011384 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; DNA-binding transcriptional repressor DeoR complement(1010626..1011384) Escherichia coli O157:H7 str. EC4115 6971498 YP_002269510.1 CDS ECH74115_0994 NC_011353.1 1011442 1012038 R identified by match to protein family HMM PF01569; undecaprenyl pyrophosphate phosphatase complement(1011442..1012038) Escherichia coli O157:H7 str. EC4115 6970809 YP_002269511.1 CDS mdfA NC_011353.1 1012323 1013555 D identified by match to protein family HMM PF07690; multidrug translocase MdfA 1012323..1013555 Escherichia coli O157:H7 str. EC4115 6970133 YP_002269512.1 CDS ECH74115_0996 NC_011353.1 1013596 1013874 R hypothetical protein complement(1013596..1013874) Escherichia coli O157:H7 str. EC4115 6972150 YP_002269513.1 CDS ybjI NC_011353.1 1013966 1014781 R identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YbjI complement(1013966..1014781) Escherichia coli O157:H7 str. EC4115 6971722 YP_002269514.1 CDS ECH74115_0998 NC_011353.1 1014781 1015989 R identified by match to protein family HMM PF07690; major facilitator family transporter complement(1014781..1015989) Escherichia coli O157:H7 str. EC4115 6971092 YP_002269515.1 CDS ECH74115_0999 NC_011353.1 1016073 1016609 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1016073..1016609 Escherichia coli O157:H7 str. EC4115 6968856 YP_002269516.1 CDS ECH74115_1001 NC_011353.1 1016784 1018469 R identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein complement(1016784..1018469) Escherichia coli O157:H7 str. EC4115 6972313 YP_002269517.1 CDS ECH74115_1002 NC_011353.1 1018739 1019116 D hypothetical protein 1018739..1019116 Escherichia coli O157:H7 str. EC4115 6970477 YP_002269518.1 CDS grxA NC_011353.1 1019146 1019403 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(1019146..1019403) Escherichia coli O157:H7 str. EC4115 6969866 YP_002269519.1 CDS ECH74115_1004 NC_011353.1 1019563 1019850 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1019563..1019850 Escherichia coli O157:H7 str. EC4115 6969555 YP_002269520.1 CDS nfsA NC_011353.1 1019834 1020556 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1019834..1020556 Escherichia coli O157:H7 str. EC4115 6969264 YP_002269521.1 CDS rimK NC_011353.1 1020617 1021519 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1020617..1021519 Escherichia coli O157:H7 str. EC4115 6966910 YP_002269522.1 CDS ECH74115_1007 NC_011353.1 1021607 1022083 D hypothetical protein 1021607..1022083 Escherichia coli O157:H7 str. EC4115 6967665 YP_002269523.1 CDS ECH74115_1008 NC_011353.1 1022040 1022162 D identified by glimmer; hypothetical protein 1022040..1022162 Escherichia coli O157:H7 str. EC4115 6968839 YP_002269524.1 CDS potF NC_011353.1 1022434 1023546 D identified by match to protein family HMM PF01547; putrescine ABC transporter periplasmic-binding protein 1022434..1023546 Escherichia coli O157:H7 str. EC4115 6967830 YP_002269525.1 CDS potG NC_011353.1 1023641 1024774 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 1023641..1024774 Escherichia coli O157:H7 str. EC4115 6968452 YP_002269526.1 CDS potH NC_011353.1 1024784 1025737 D identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 1024784..1025737 Escherichia coli O157:H7 str. EC4115 6972005 YP_002269527.1 CDS potI NC_011353.1 1025734 1026579 D identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 1025734..1026579 Escherichia coli O157:H7 str. EC4115 6967781 YP_002269528.1 CDS ECH74115_1014 NC_011353.1 1026639 1027127 D hypothetical protein 1026639..1027127 Escherichia coli O157:H7 str. EC4115 6970914 YP_002269529.1 CDS rumB NC_011353.1 1027168 1028295 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1027168..1028295 Escherichia coli O157:H7 str. EC4115 6968423 YP_002269530.1 CDS ECH74115_1016 NC_011353.1 1028575 1029918 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1028575..1029918 Escherichia coli O157:H7 str. EC4115 6970325 YP_002269531.1 CDS ECH74115_1018 NC_011353.1 1030272 1031753 D identified by match to protein family HMM PF00884; sulfatase 1030272..1031753 Escherichia coli O157:H7 str. EC4115 6970024 YP_002269532.1 CDS artJ NC_011353.1 1031804 1032535 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter periplasmic substrate-binding protein ArtJ complement(1031804..1032535) Escherichia coli O157:H7 str. EC4115 6970815 YP_002269533.1 CDS ECH74115_1020 NC_011353.1 1032689 1032826 R hypothetical protein complement(1032689..1032826) Escherichia coli O157:H7 str. EC4115 6971202 YP_002269534.1 CDS artM NC_011353.1 1032826 1033494 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(1032826..1033494) Escherichia coli O157:H7 str. EC4115 6967886 YP_002269535.1 CDS artQ NC_011353.1 1033494 1034210 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(1033494..1034210) Escherichia coli O157:H7 str. EC4115 6967000 YP_002269536.1 CDS artI NC_011353.1 1034217 1034948 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter substrate-binding protein complement(1034217..1034948) Escherichia coli O157:H7 str. EC4115 6969019 YP_002269537.1 CDS artP NC_011353.1 1034966 1035694 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(1034966..1035694) Escherichia coli O157:H7 str. EC4115 6968066 YP_002269538.1 CDS ECH74115_1025 NC_011353.1 1035912 1036427 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(1035912..1036427) Escherichia coli O157:H7 str. EC4115 6970585 YP_002269539.1 CDS ECH74115_1026 NC_011353.1 1037051 1038850 D identified by glimmer; hypothetical protein 1037051..1038850 Escherichia coli O157:H7 str. EC4115 6969558 YP_002269540.1 CDS ECH74115_1027 NC_011353.1 1039061 1039384 D identified by match to protein family HMM PF01906; hypothetical protein 1039061..1039384 Escherichia coli O157:H7 str. EC4115 6968734 YP_002269541.1 CDS amiD NC_011353.1 1039381 1040211 D identified by match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase AmiD 1039381..1040211 Escherichia coli O157:H7 str. EC4115 6968965 YP_002269542.1 CDS ECH74115_1028 NC_011353.1 1040208 1041257 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase family protein complement(1040208..1041257) Escherichia coli O157:H7 str. EC4115 6967017 YP_002269543.1 CDS ECH74115_1030 NC_011353.1 1041320 1042750 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; NAD dependent epimerase/dehydratase family protein complement(1041320..1042750) Escherichia coli O157:H7 str. EC4115 6967936 YP_002269544.1 CDS ltaE NC_011353.1 1042761 1043762 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(1042761..1043762) Escherichia coli O157:H7 str. EC4115 6966822 YP_002269545.1 CDS poxB NC_011353.1 1043799 1045517 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(1043799..1045517) Escherichia coli O157:H7 str. EC4115 6972107 YP_002269546.1 CDS hcr NC_011353.1 1045650 1046618 R identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; HCP oxidoreductase complement(1045650..1046618) Escherichia coli O157:H7 str. EC4115 6971411 YP_002269547.1 CDS hcp NC_011353.1 1046630 1048282 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(1046630..1048282) Escherichia coli O157:H7 str. EC4115 6970579 YP_002269548.1 CDS ECH74115_1035 NC_011353.1 1048426 1049325 R identified by match to protein family HMM PF03956; hypothetical protein complement(1048426..1049325) Escherichia coli O157:H7 str. EC4115 6970020 YP_002269549.1 CDS aqpZ NC_011353.1 1049783 1050478 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(1049783..1050478) Escherichia coli O157:H7 str. EC4115 6970079 YP_002269550.1 CDS ECH74115_1038 NC_011353.1 1050904 1052562 D hypothetical protein 1050904..1052562 Escherichia coli O157:H7 str. EC4115 6968722 YP_002269551.1 CDS ECH74115_1037 NC_011353.1 1052559 1053551 R identified by match to protein family HMM PF04393; hypothetical protein complement(1052559..1053551) Escherichia coli O157:H7 str. EC4115 6967466 YP_002269552.1 CDS macA NC_011353.1 1053666 1054781 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1053666..1054781 Escherichia coli O157:H7 str. EC4115 6968079 YP_002269553.1 CDS macB NC_011353.1 1054778 1056724 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1054778..1056724 Escherichia coli O157:H7 str. EC4115 6966959 YP_002269554.1 CDS cspD NC_011353.1 1056797 1057021 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(1056797..1057021) Escherichia coli O157:H7 str. EC4115 6966723 YP_002269555.1 CDS clpS NC_011353.1 1057344 1057664 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1057344..1057664 Escherichia coli O157:H7 str. EC4115 6971421 YP_002269556.1 CDS clpA NC_011353.1 1057695 1059971 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1057695..1059971 Escherichia coli O157:H7 str. EC4115 6970638 YP_002269557.1 CDS infA NC_011353.1 1060658 1060876 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1060658..1060876) Escherichia coli O157:H7 str. EC4115 6972349 YP_002269558.1 CDS aat NC_011353.1 1061161 1061865 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(1061161..1061865) Escherichia coli O157:H7 str. EC4115 6968276 YP_002269559.1 CDS cydC NC_011353.1 1061907 1063628 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1061907..1063628) Escherichia coli O157:H7 str. EC4115 6970623 YP_002269560.1 CDS cydD NC_011353.1 1063629 1065395 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1063629..1065395) Escherichia coli O157:H7 str. EC4115 6969908 YP_002269561.1 CDS trxB NC_011353.1 1065518 1066483 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(1065518..1066483) Escherichia coli O157:H7 str. EC4115 6972125 YP_002269562.1 CDS lrp NC_011353.1 1067028 1067522 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1067028..1067522 Escherichia coli O157:H7 str. EC4115 6971503 YP_002269563.1 CDS ftsK NC_011353.1 1067657 1071685 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 1067657..1071685 Escherichia coli O157:H7 str. EC4115 6967288 YP_002269564.1 CDS lolA NC_011353.1 1071840 1072451 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1071840..1072451 Escherichia coli O157:H7 str. EC4115 6967789 YP_002269565.1 CDS ECH74115_1054 NC_011353.1 1072462 1073805 D identified by match to protein family HMM PF00004; recombination factor protein RarA 1072462..1073805 Escherichia coli O157:H7 str. EC4115 6968898 YP_002269566.1 CDS serS NC_011353.1 1073896 1075188 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1073896..1075188 Escherichia coli O157:H7 str. EC4115 6967991 YP_002269567.1 CDS dmsA NC_011353.1 1075427 1077871 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 1075427..1077871 Escherichia coli O157:H7 str. EC4115 6967513 YP_002269568.1 CDS dmsB_1 NC_011353.1 1077882 1078499 D identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951; anaerobic dimethylsulfoxide reductase subunit B 1077882..1078499 Escherichia coli O157:H7 str. EC4115 6971285 YP_002269569.1 CDS dmsC1 NC_011353.1 1078501 1079364 D identified by match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 1078501..1079364 Escherichia coli O157:H7 str. EC4115 6970475 YP_002269570.1 CDS ECH74115_1059 NC_011353.1 1079400 1080026 R identified by match to protein family HMM PF00857; isochorismatase family protein complement(1079400..1080026) Escherichia coli O157:H7 str. EC4115 6969973 YP_002269571.1 CDS ECH74115_1060 NC_011353.1 1080182 1080310 R identified by glimmer; hypothetical protein complement(1080182..1080310) Escherichia coli O157:H7 str. EC4115 6968822 YP_002269572.1 CDS ECH74115_1061 NC_011353.1 1080341 1081489 D identified by match to protein family HMM PF07690; MFS family transporter protein 1080341..1081489 Escherichia coli O157:H7 str. EC4115 6968758 YP_002269573.1 CDS ECH74115_1062 NC_011353.1 1081699 1083129 D identified by match to protein family HMM PF00324; amino acid permease family protein 1081699..1083129 Escherichia coli O157:H7 str. EC4115 6967990 YP_002269574.1 CDS pflA NC_011353.1 1083339 1084079 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1083339..1084079) Escherichia coli O157:H7 str. EC4115 6967501 YP_002269575.1 CDS pflB2 NC_011353.1 1084271 1086553 R identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase complement(1084271..1086553) Escherichia coli O157:H7 str. EC4115 6972072 YP_002269576.1 CDS ECH74115_1065 NC_011353.1 1086608 1087465 R identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790; formate transporter complement(1086608..1087465) Escherichia coli O157:H7 str. EC4115 6970502 YP_002269577.1 CDS ECH74115_1066 NC_011353.1 1087871 1089631 R identified by match to protein family HMM PF02624; match to protein family HMM TIGR00702; hypothetical protein complement(1087871..1089631) Escherichia coli O157:H7 str. EC4115 6967958 YP_002269578.1 CDS ECH74115_1067 NC_011353.1 1089761 1090453 D identified by match to protein family HMM PF04239; hypothetical protein 1089761..1090453 Escherichia coli O157:H7 str. EC4115 6966592 YP_002269579.1 CDS serC NC_011353.1 1090652 1091740 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1090652..1091740 Escherichia coli O157:H7 str. EC4115 6971665 YP_002269580.1 CDS aroA NC_011353.1 1091811 1093094 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1091811..1093094 Escherichia coli O157:H7 str. EC4115 6972112 YP_002269581.1 CDS ECH74115_1070 NC_011353.1 1093239 1094027 D identified by match to protein family HMM PF01435; peptidase, M48B family 1093239..1094027 Escherichia coli O157:H7 str. EC4115 6971487 YP_002269582.1 CDS cmk NC_011353.1 1094200 1094883 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1094200..1094883 Escherichia coli O157:H7 str. EC4115 6970099 YP_002269583.1 CDS rpsA NC_011353.1 1094994 1096667 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1094994..1096667 Escherichia coli O157:H7 str. EC4115 6969081 YP_002269584.1 CDS ihfB NC_011353.1 1096827 1097111 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1096827..1097111 Escherichia coli O157:H7 str. EC4115 6968443 YP_002269585.1 CDS ECH74115_1074 NC_011353.1 1097318 1099582 D identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; hypothetical protein 1097318..1099582 Escherichia coli O157:H7 str. EC4115 6967476 YP_002269586.1 CDS msbA NC_011353.1 1099619 1101367 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1099619..1101367 Escherichia coli O157:H7 str. EC4115 6971625 YP_002269587.1 CDS lpxK NC_011353.1 1101364 1102350 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1101364..1102350 Escherichia coli O157:H7 str. EC4115 6969538 YP_002269588.1 CDS ECH74115_1077 NC_011353.1 1102387 1103619 D identified by match to protein family HMM PF06224; hypothetical protein 1102387..1103619 Escherichia coli O157:H7 str. EC4115 6971131 YP_002269589.1 CDS ECH74115_1078 NC_011353.1 1103671 1103853 D identified by match to protein family HMM PF03966; hypothetical protein 1103671..1103853 Escherichia coli O157:H7 str. EC4115 6969770 YP_002269590.1 CDS kdsB NC_011353.1 1103850 1104596 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1103850..1104596 Escherichia coli O157:H7 str. EC4115 6970530 YP_002269591.1 CDS ECH74115_1081 NC_011353.1 1104750 1105643 D hypothetical protein 1104750..1105643 Escherichia coli O157:H7 str. EC4115 6970288 YP_002269592.1 CDS ECH74115_1080 NC_011353.1 1105620 1106399 R identified by match to protein family HMM PF02698; hypothetical protein complement(1105620..1106399) Escherichia coli O157:H7 str. EC4115 6969156 YP_002269593.1 CDS smtA NC_011353.1 1106535 1107320 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1106535..1107320 Escherichia coli O157:H7 str. EC4115 6968363 YP_002269594.1 CDS mukF NC_011353.1 1107317 1108639 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1107317..1108639 Escherichia coli O157:H7 str. EC4115 6967115 YP_002269595.1 CDS mukE NC_011353.1 1108593 1109324 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1108593..1109324 Escherichia coli O157:H7 str. EC4115 6967891 YP_002269596.1 CDS mukB NC_011353.1 1109324 1113784 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1109324..1113784 Escherichia coli O157:H7 str. EC4115 6971746 YP_002269597.1 CDS ECH74115_1086 NC_011353.1 1114057 1115892 D identified by match to protein family HMM PF01471; hypothetical protein 1114057..1115892 Escherichia coli O157:H7 str. EC4115 6968180 YP_002269598.1 CDS ECH74115_1087 NC_011353.1 1116073 1116621 D identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409; exported protein, Tat-dependent 1116073..1116621 Escherichia coli O157:H7 str. EC4115 6971137 YP_002269599.1 CDS ECH74115_1088 NC_011353.1 1116648 1117295 D identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 1116648..1117295 Escherichia coli O157:H7 str. EC4115 6967643 YP_002269600.1 CDS aspC NC_011353.1 1117346 1118536 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1117346..1118536) Escherichia coli O157:H7 str. EC4115 6966649 YP_002269601.1 CDS ompF NC_011353.1 1118721 1119809 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1118721..1119809) Escherichia coli O157:H7 str. EC4115 6968818 YP_002269602.1 CDS asnC NC_011353.1 1120412 1121812 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1120412..1121812) Escherichia coli O157:H7 str. EC4115 6968823 YP_002269603.1 CDS pncB NC_011353.1 1121981 1123183 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1121981..1123183) Escherichia coli O157:H7 str. EC4115 6967970 YP_002269604.1 CDS pepN NC_011353.1 1123449 1126061 D identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414; aminopeptidase N 1123449..1126061 Escherichia coli O157:H7 str. EC4115 6969524 YP_002269605.1 CDS ssuB NC_011353.1 1126104 1126871 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1126104..1126871) Escherichia coli O157:H7 str. EC4115 6967604 YP_002269606.1 CDS ssuC NC_011353.1 1126868 1127659 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease complement(1126868..1127659) Escherichia coli O157:H7 str. EC4115 6969953 YP_002269607.1 CDS ssuD NC_011353.1 1127671 1128816 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1127671..1128816) Escherichia coli O157:H7 str. EC4115 6971915 YP_002269608.1 CDS ECH74115_1098 NC_011353.1 1128813 1129772 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1128813..1129772) Escherichia coli O157:H7 str. EC4115 6969690 YP_002269609.1 CDS ECH74115_1099 NC_011353.1 1129765 1130340 R identified by match to protein family HMM PF02525; match to protein family HMM PF03358; match to protein family HMM TIGR03567; NAD(P)H-dependent FMN reductase complement(1129765..1130340) Escherichia coli O157:H7 str. EC4115 6967483 YP_002269610.1 CDS ECH74115_1100 NC_011353.1 1130696 1131235 D identified by match to protein family HMM PF00419; fimbrial protein 1130696..1131235 Escherichia coli O157:H7 str. EC4115 6970853 YP_002269611.1 CDS ECH74115_1101 NC_011353.1 1131345 1132019 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 1131345..1132019 Escherichia coli O157:H7 str. EC4115 6967162 YP_002269612.1 CDS ECH74115_1105 NC_011353.1 1135807 1136259 D identified by match to protein family HMM PF00419; fimbrial protein 1135807..1136259 Escherichia coli O157:H7 str. EC4115 6971354 YP_002269613.1 CDS ECH74115_1106 NC_011353.1 1136270 1136782 D identified by match to protein family HMM PF00419; fimbrial protein 1136270..1136782 Escherichia coli O157:H7 str. EC4115 6971645 YP_002269614.1 CDS pyrD NC_011353.1 1137595 1138605 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1137595..1138605 Escherichia coli O157:H7 str. EC4115 6966835 YP_002269615.1 CDS ECH74115_1111 NC_011353.1 1138779 1139321 D identified by match to protein family HMM PF07126; hypothetical protein 1138779..1139321 Escherichia coli O157:H7 str. EC4115 6968434 YP_002269616.1 CDS ECH74115_1110 NC_011353.1 1139318 1140427 R identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476; MOSC domain-containing protein complement(1139318..1140427) Escherichia coli O157:H7 str. EC4115 6968684 YP_002269617.1 CDS rlmL NC_011353.1 1140671 1142779 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1140671..1142779 Escherichia coli O157:H7 str. EC4115 6968044 YP_002269618.1 CDS uup NC_011353.1 1142791 1144698 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1142791..1144698 Escherichia coli O157:H7 str. EC4115 6970092 YP_002269619.1 CDS pqiA NC_011353.1 1144828 1146081 D identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155; paraquat-inducible protein A 1144828..1146081 Escherichia coli O157:H7 str. EC4115 6970711 YP_002269620.1 CDS pqiB NC_011353.1 1146086 1147726 D identified by match to protein family HMM PF02470; paraquat-inducible protein B 1146086..1147726 Escherichia coli O157:H7 str. EC4115 6966951 YP_002269621.1 CDS ECH74115_1116 NC_011353.1 1147723 1148286 D identified by match to protein family HMM PF03886; lipoprotein 1147723..1148286 Escherichia coli O157:H7 str. EC4115 6970628 YP_002269622.1 CDS fabA NC_011353.1 1148779 1149297 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1148779..1149297) Escherichia coli O157:H7 str. EC4115 6970250 YP_002269623.1 CDS ECH74115_1119 NC_011353.1 1149366 1151126 R identified by match to protein family HMM PF05362; peptidase S16 complement(1149366..1151126) Escherichia coli O157:H7 str. EC4115 6966958 YP_002269624.1 CDS ECH74115_1120 NC_011353.1 1151312 1151764 D identified by match to protein family HMM PF06303; hypothetical protein 1151312..1151764 Escherichia coli O157:H7 str. EC4115 6972080 YP_002269625.1 CDS ompA NC_011353.1 1151839 1152903 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1151839..1152903) Escherichia coli O157:H7 str. EC4115 6969157 YP_002269626.1 CDS ECH74115_1122 NC_011353.1 1153236 1153745 R identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623; SOS cell division inhibitor complement(1153236..1153745) Escherichia coli O157:H7 str. EC4115 6968358 YP_002269627.1 CDS ECH74115_1124 NC_011353.1 1153964 1154593 D identified by match to protein family HMM PF04993; match to protein family HMM PF04994; TfoX family protein 1153964..1154593 Escherichia coli O157:H7 str. EC4115 6970509 YP_002269628.1 CDS ECH74115_1123 NC_011353.1 1154556 1156718 R identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667; hypothetical protein complement(1154556..1156718) Escherichia coli O157:H7 str. EC4115 6970627 YP_002269629.1 CDS ECH74115_1125 NC_011353.1 1156728 1157174 R identified by match to protein family HMM PF03733; hypothetical protein complement(1156728..1157174) Escherichia coli O157:H7 str. EC4115 6969868 YP_002269630.1 CDS helD NC_011353.1 1157297 1159351 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1157297..1159351 Escherichia coli O157:H7 str. EC4115 6971402 YP_002269631.1 CDS mgsA NC_011353.1 1159383 1159841 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1159383..1159841) Escherichia coli O157:H7 str. EC4115 6971432 YP_002269632.1 CDS ECH74115_1128 NC_011353.1 1159937 1160599 R hypothetical protein complement(1159937..1160599) Escherichia coli O157:H7 str. EC4115 6966560 YP_002269633.1 CDS ECH74115_1129 NC_011353.1 1160639 1160797 R identified by glimmer; hypothetical protein complement(1160639..1160797) Escherichia coli O157:H7 str. EC4115 6969810 YP_002269634.1 CDS ECH74115_1130 NC_011353.1 1160772 1161185 D identified by match to protein family HMM PF02629; CoA-binding protein 1160772..1161185 Escherichia coli O157:H7 str. EC4115 6970634 YP_002269635.1 CDS ECH74115_1131 NC_011353.1 1161230 1161547 R identified by match to protein family HMM PF08755; match to protein family HMM TIGR02097; heat shock protein HspQ complement(1161230..1161547) Escherichia coli O157:H7 str. EC4115 6968184 YP_002269636.1 CDS ECH74115_1132 NC_011353.1 1161605 1162795 R identified by match to protein family HMM PF03602; hypothetical protein complement(1161605..1162795) Escherichia coli O157:H7 str. EC4115 6969020 YP_002269637.1 CDS ECH74115_1134 NC_011353.1 1162890 1163168 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1162890..1163168 Escherichia coli O157:H7 str. EC4115 6972223 YP_002269638.1 CDS tusE NC_011353.1 1163165 1163494 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1163165..1163494) Escherichia coli O157:H7 str. EC4115 6966637 YP_002269639.1 CDS ECH74115_1135 NC_011353.1 1163585 1164244 R identified by match to protein family HMM PF01027; hypothetical protein complement(1163585..1164244) Escherichia coli O157:H7 str. EC4115 6971471 YP_002269640.1 CDS ECH74115_1138 NC_011353.1 1165636 1165878 R hypothetical protein complement(1165636..1165878) Escherichia coli O157:H7 str. EC4115 6971180 YP_002269641.1 CDS ECH74115_1139 NC_011353.1 1165946 1168417 R exonuclease family protein complement(1165946..1168417) Escherichia coli O157:H7 str. EC4115 6967605 YP_002269642.1 CDS ECH74115_1140 NC_011353.1 1168511 1168702 R identified by match to protein family HMM PF07358; hypothetical protein complement(1168511..1168702) Escherichia coli O157:H7 str. EC4115 6967066 YP_002269643.1 CDS ECH74115_1141 NC_011353.1 1168699 1168887 R identified by match to protein family HMM PF05358; DicB protein complement(1168699..1168887) Escherichia coli O157:H7 str. EC4115 6969197 YP_002269644.1 CDS ECH74115_1143 NC_011353.1 1169461 1169646 D hypothetical protein 1169461..1169646 Escherichia coli O157:H7 str. EC4115 6970311 YP_002269645.1 CDS ECH74115_1144 NC_011353.1 1169833 1170222 R hypothetical protein complement(1169833..1170222) Escherichia coli O157:H7 str. EC4115 6969514 YP_002269646.1 CDS ECH74115_1145 NC_011353.1 1170234 1170362 R hypothetical protein complement(1170234..1170362) Escherichia coli O157:H7 str. EC4115 6967907 YP_002269647.1 CDS ECH74115_1147 NC_011353.1 1171084 1171275 R hypothetical protein complement(1171084..1171275) Escherichia coli O157:H7 str. EC4115 6972010 YP_002269648.1 CDS ECH74115_1148 NC_011353.1 1171303 1171551 R hypothetical protein complement(1171303..1171551) Escherichia coli O157:H7 str. EC4115 6966899 YP_002269649.1 CDS ECH74115_1149 NC_011353.1 1171957 1172085 D hypothetical protein 1171957..1172085 Escherichia coli O157:H7 str. EC4115 6970717 YP_002269650.1 CDS ECH74115_1150 NC_011353.1 1172096 1172494 D identified by match to protein family HMM PF06254; hypothetical protein 1172096..1172494 Escherichia coli O157:H7 str. EC4115 6970964 YP_002269651.1 CDS ECH74115_1151 NC_011353.1 1172460 1173017 D hypothetical protein 1172460..1173017 Escherichia coli O157:H7 str. EC4115 6968108 YP_002269652.1 CDS ECH74115_1152 NC_011353.1 1173124 1174326 D hypothetical protein 1173124..1174326 Escherichia coli O157:H7 str. EC4115 6968794 YP_002269653.1 CDS ECH74115_1153 NC_011353.1 1174333 1175079 D identified by match to protein family HMM PF01695; replication protein 1174333..1175079 Escherichia coli O157:H7 str. EC4115 6966738 YP_002269654.1 CDS ECH74115_1154 NC_011353.1 1175101 1175871 D identified by match to protein family HMM PF07789; hypothetical protein 1175101..1175871 Escherichia coli O157:H7 str. EC4115 6967491 YP_002269655.1 CDS ECH74115_1155 NC_011353.1 1175887 1176300 D identified by match to protein family HMM PF06163; hypothetical protein 1175887..1176300 Escherichia coli O157:H7 str. EC4115 6967018 YP_002269656.1 CDS ECH74115_1156 NC_011353.1 1176652 1177425 R hypothetical protein complement(1176652..1177425) Escherichia coli O157:H7 str. EC4115 6967678 YP_002269657.1 CDS ECH74115_1158 NC_011353.1 1178633 1179682 D identified by match to protein family HMM PF06914; hypothetical protein 1178633..1179682 Escherichia coli O157:H7 str. EC4115 6972156 YP_002269658.1 CDS ECH74115_1159 NC_011353.1 1179695 1180066 D identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1179695..1180066 Escherichia coli O157:H7 str. EC4115 6967065 YP_002269659.1 CDS ECH74115_1160 NC_011353.1 1180302 1180427 D phage antitermination Q type 1 family protein 1180302..1180427 Escherichia coli O157:H7 str. EC4115 6971720 YP_002269660.1 CDS ECH74115_1161 NC_011353.1 1180579 1181397 D identified by match to protein family HMM PF02517; abortive infection protein 1180579..1181397 Escherichia coli O157:H7 str. EC4115 6967756 YP_002269661.1 CDS ECH74115_1163 NC_011353.1 1181987 1182127 R identified by glimmer; hypothetical protein complement(1181987..1182127) Escherichia coli O157:H7 str. EC4115 6971123 YP_002269662.1 CDS ECH74115_1164 NC_011353.1 1182144 1182731 D identified by match to protein family HMM PF00165; envelope protein encoded within prophage CP-933N 1182144..1182731 Escherichia coli O157:H7 str. EC4115 6969511 YP_002269663.1 CDS ECH74115_1168 NC_011353.1 1183499 1185349 D identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 1183499..1185349 Escherichia coli O157:H7 str. EC4115 6972429 YP_002269664.1 CDS ECH74115_1169 NC_011353.1 1185525 1185851 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 1185525..1185851 Escherichia coli O157:H7 str. EC4115 6971113 YP_002269665.1 CDS ECH74115_1170 NC_011353.1 1185848 1186738 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1185848..1186738 Escherichia coli O157:H7 str. EC4115 6971521 YP_002269666.1 CDS ECH74115_1171 NC_011353.1 1187500 1187640 R hypothetical protein complement(1187500..1187640) Escherichia coli O157:H7 str. EC4115 6969477 YP_002269667.1 CDS ECH74115_1172 NC_011353.1 1187723 1188190 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(1187723..1188190) Escherichia coli O157:H7 str. EC4115 6969944 YP_002269668.1 CDS ECH74115_1173 NC_011353.1 1188192 1188305 R identified by glimmer; hypothetical protein complement(1188192..1188305) Escherichia coli O157:H7 str. EC4115 6968633 YP_002269669.1 CDS ECH74115_1174 NC_011353.1 1188526 1189059 R identified by match to protein family HMM PF00959; lysozyme complement(1188526..1189059) Escherichia coli O157:H7 str. EC4115 6969313 YP_002269670.1 CDS ECH74115_1175 NC_011353.1 1189177 1189491 D hypothetical protein 1189177..1189491 Escherichia coli O157:H7 str. EC4115 6966911 YP_002269671.1 CDS ECH74115_1176 NC_011353.1 1189747 1189911 R identified by match to protein family HMM PF04971; hypothetical protein complement(1189747..1189911) Escherichia coli O157:H7 str. EC4115 6967511 YP_002269672.1 CDS ECH74115_1177 NC_011353.1 1189981 1190307 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 1189981..1190307 Escherichia coli O157:H7 str. EC4115 6970169 YP_002269673.1 CDS ECH74115_1178 NC_011353.1 1190304 1191194 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1190304..1191194 Escherichia coli O157:H7 str. EC4115 6970970 YP_002269674.1 CDS ECH74115_1179 NC_011353.1 1191274 1191435 D hypothetical protein 1191274..1191435 Escherichia coli O157:H7 str. EC4115 6970635 YP_002269675.1 CDS ECH74115_1180 NC_011353.1 1192017 1192292 D hypothetical protein 1192017..1192292 Escherichia coli O157:H7 str. EC4115 6971793 YP_002269676.1 CDS ECH74115_1181 NC_011353.1 1192587 1192748 D IS66 family element, orf1 1192587..1192748 Escherichia coli O157:H7 str. EC4115 6970026 YP_002269677.1 CDS ECH74115_1182 NC_011353.1 1192745 1193092 D identified by match to protein family HMM PF05717; IS66 family element, orf2 1192745..1193092 Escherichia coli O157:H7 str. EC4115 6970679 YP_002269678.1 CDS ECH74115_1183 NC_011353.1 1193142 1194680 D identified by match to protein family HMM PF03050; IS66 family element, transposase 1193142..1194680 Escherichia coli O157:H7 str. EC4115 6967297 YP_002269679.1 CDS ECH74115_1184 NC_011353.1 1194730 1194972 D DNA packaging Nu1 1194730..1194972 Escherichia coli O157:H7 str. EC4115 6968284 YP_002269680.1 CDS ECH74115_1187 NC_011353.1 1196857 1197063 D identified by match to protein family HMM PF02831; gpW 1196857..1197063 Escherichia coli O157:H7 str. EC4115 6970606 YP_002269681.1 CDS ECH74115_1188 NC_011353.1 1197060 1198652 D identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1197060..1198652 Escherichia coli O157:H7 str. EC4115 6971384 YP_002269682.1 CDS ECH74115_1189 NC_011353.1 1198642 1200147 D identified by match to protein family HMM PF01343; head-tail preconnector protein GP5 1198642..1200147 Escherichia coli O157:H7 str. EC4115 6969939 YP_002269683.1 CDS ECH74115_1190 NC_011353.1 1200184 1200531 D identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1200184..1200531 Escherichia coli O157:H7 str. EC4115 6969488 YP_002269684.1 CDS ECH74115_1191 NC_011353.1 1200589 1200855 D major head protein 1200589..1200855 Escherichia coli O157:H7 str. EC4115 6967252 YP_002269685.1 CDS ECH74115_1192 NC_011353.1 1200915 1201577 D identified by match to protein family HMM PF02368; major tail protein V 1200915..1201577 Escherichia coli O157:H7 str. EC4115 6968272 YP_002269686.1 CDS ECH74115_1193 NC_011353.1 1201591 1202022 D identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 1201591..1202022 Escherichia coli O157:H7 str. EC4115 6966886 YP_002269687.1 CDS ECH74115_1194 NC_011353.1 1202073 1202462 D identified by match to protein family HMM TIGR01715; phage tail assembly protein T 1202073..1202462 Escherichia coli O157:H7 str. EC4115 6967684 YP_002269688.1 CDS ECH74115_1195 NC_011353.1 1202443 1205022 D identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1202443..1205022 Escherichia coli O157:H7 str. EC4115 6971225 YP_002269689.1 CDS ECH74115_1196 NC_011353.1 1205019 1205348 D identified by match to protein family HMM PF05939; phage minor tail protein 1205019..1205348 Escherichia coli O157:H7 str. EC4115 6972019 YP_002269690.1 CDS ECH74115_1197 NC_011353.1 1205348 1206046 D identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1205348..1206046 Escherichia coli O157:H7 str. EC4115 6968109 YP_002269691.1 CDS ECH74115_1198 NC_011353.1 1206165 1206800 D identified by match to protein family HMM PF00877; tail assembly protein 1206165..1206800 Escherichia coli O157:H7 str. EC4115 6969984 YP_002269692.1 CDS ECH74115_1199 NC_011353.1 1206797 1207378 D identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1206797..1207378 Escherichia coli O157:H7 str. EC4115 6968000 YP_002269693.1 CDS ECH74115_1200 NC_011353.1 1207569 1208228 R identified by match to protein family HMM PF00080; superoxide dismutase complement(1207569..1208228) Escherichia coli O157:H7 str. EC4115 6970792 YP_002269694.1 CDS ECH74115_1201 NC_011353.1 1208230 1211703 D identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 1208230..1211703 Escherichia coli O157:H7 str. EC4115 6966837 YP_002269695.1 CDS ECH74115_1202 NC_011353.1 1211771 1212370 D identified by match to protein family HMM PF06316; Ail/Lom family protein 1211771..1212370 Escherichia coli O157:H7 str. EC4115 6968812 YP_002269696.1 CDS ECH74115_1203 NC_011353.1 1212392 1213747 D identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 1212392..1213747 Escherichia coli O157:H7 str. EC4115 6970093 YP_002269697.1 CDS ECH74115_1204 NC_011353.1 1213749 1214018 D identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 1213749..1214018 Escherichia coli O157:H7 str. EC4115 6971893 YP_002269698.1 CDS hyaA NC_011353.1 1216292 1217410 D identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; nickel-dependent hydrogenase 1, small subunit 1216292..1217410 Escherichia coli O157:H7 str. EC4115 6968975 YP_002269699.1 CDS hyaB NC_011353.1 1217407 1219200 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1217407..1219200 Escherichia coli O157:H7 str. EC4115 6968164 YP_002269700.1 CDS hyaC NC_011353.1 1219219 1219926 D identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125; hydrogenase 1 b-type cytochrome subunit 1219219..1219926 Escherichia coli O157:H7 str. EC4115 6971195 YP_002269701.1 CDS hyaD NC_011353.1 1219923 1220510 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1219923..1220510 Escherichia coli O157:H7 str. EC4115 6967902 YP_002269702.1 CDS hyaE NC_011353.1 1220507 1220905 D involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1220507..1220905 Escherichia coli O157:H7 str. EC4115 6969574 YP_002269703.1 CDS hyaF NC_011353.1 1220902 1221759 D identified by match to protein family HMM PF04809; hydrogenase-1 operon protein HyaF 1220902..1221759 Escherichia coli O157:H7 str. EC4115 6972060 YP_002269704.1 CDS appC NC_011353.1 1221893 1223437 D identified by match to protein family HMM PF01654; cytochrome bd-II oxidase subunit I 1221893..1223437 Escherichia coli O157:H7 str. EC4115 6967934 YP_002269705.1 CDS appB NC_011353.1 1223449 1224585 D identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome bd-II oxidase subunit II 1223449..1224585 Escherichia coli O157:H7 str. EC4115 6970227 YP_002269706.1 CDS appA NC_011353.1 1224770 1226074 D identified by match to protein family HMM PF00328; phosphoanhydride phosphorylase 1224770..1226074 Escherichia coli O157:H7 str. EC4115 6969232 YP_002269707.1 CDS etk1 NC_011353.1 1226194 1228374 R identified by match to protein family HMM PF02706; match to protein family HMM TIGR01007; cryptic autophosphorylating protein tyrosine kinase Etk complement(1226194..1228374) Escherichia coli O157:H7 str. EC4115 6968611 YP_002269708.1 CDS etp NC_011353.1 1228394 1228840 R Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase complement(1228394..1228840) Escherichia coli O157:H7 str. EC4115 6972081 YP_002269709.1 CDS yccZ NC_011353.1 1228828 1229967 R identified by match to protein family HMM PF02563; outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide complement(1228828..1229967) Escherichia coli O157:H7 str. EC4115 6971451 YP_002269710.1 CDS ymcA NC_011353.1 1230013 1232109 R identified by match to protein family HMM PF06082; group 4 capsule (G4C) polysaccharide, lipoprotein YmcA complement(1230013..1232109) Escherichia coli O157:H7 str. EC4115 6969340 YP_002269711.1 CDS ymcB NC_011353.1 1232109 1232855 R identified by match to protein family HMM PF06251; group 4 capsule (G4C) polysaccharide, YmcB complement(1232109..1232855) Escherichia coli O157:H7 str. EC4115 6966654 YP_002269712.1 CDS ymcC NC_011353.1 1232852 1233496 R group 4 capsule (G4C) polysaccharide, lipoprotein YmcC complement(1232852..1233496) Escherichia coli O157:H7 str. EC4115 6967386 YP_002269713.1 CDS ECH74115_1223 NC_011353.1 1233603 1233908 R inner membrane protein complement(1233603..1233908) Escherichia coli O157:H7 str. EC4115 6971112 YP_002269714.1 CDS ECH74115_1224 NC_011353.1 1234350 1234562 R identified by match to protein family HMM PF00313; cold shock DNA-binding protein complement(1234350..1234562) Escherichia coli O157:H7 str. EC4115 6971756 YP_002269715.1 CDS ECH74115_1225 NC_011353.1 1234848 1235060 D identified by match to protein family HMM PF00313; cold shock protein CspG 1234848..1235060 Escherichia coli O157:H7 str. EC4115 6972014 YP_002269716.1 CDS ECH74115_1226 NC_011353.1 1235140 1235259 D identified by glimmer; hypothetical protein 1235140..1235259 Escherichia coli O157:H7 str. EC4115 6969306 YP_002269717.1 CDS ECH74115_1227 NC_011353.1 1235432 1235638 R hypothetical protein complement(1235432..1235638) Escherichia coli O157:H7 str. EC4115 6966929 YP_002269718.1 CDS ECH74115_1228 NC_011353.1 1235675 1236748 R identified by match to protein family HMM PF00037; 4Fe-4S binding protein complement(1235675..1236748) Escherichia coli O157:H7 str. EC4115 6967697 YP_002269719.1 CDS torS NC_011353.1 1236820 1239534 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1236820..1239534) Escherichia coli O157:H7 str. EC4115 6971882 YP_002269720.1 CDS torT NC_011353.1 1239647 1240675 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1239647..1240675 Escherichia coli O157:H7 str. EC4115 6967793 YP_002269721.1 CDS torR NC_011353.1 1240648 1241340 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1240648..1241340) Escherichia coli O157:H7 str. EC4115 6966717 YP_002269722.1 CDS torC NC_011353.1 1241470 1242642 D identified by match to protein family HMM PF03264; match to protein family HMM TIGR02162; cytochrome c-type protein torC 1241470..1242642 Escherichia coli O157:H7 str. EC4115 6967160 YP_002269723.1 CDS torA NC_011353.1 1242642 1245188 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164; trimethylamine-N-oxide reductase 1242642..1245188 Escherichia coli O157:H7 str. EC4115 6971656 YP_002269724.1 CDS torD NC_011353.1 1245185 1245784 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1245185..1245784 Escherichia coli O157:H7 str. EC4115 6971003 YP_002269725.1 CDS cbpM NC_011353.1 1245938 1246243 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1245938..1246243) Escherichia coli O157:H7 str. EC4115 6970543 YP_002269726.1 CDS cbpA NC_011353.1 1246243 1247163 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1246243..1247163) Escherichia coli O157:H7 str. EC4115 6969876 YP_002269727.1 CDS ECH74115_1239 NC_011353.1 1248834 1248950 D identified by glimmer; hypothetical protein 1248834..1248950 Escherichia coli O157:H7 str. EC4115 6968039 YP_002269728.1 CDS agp NC_011353.1 1248971 1250212 D identified by match to protein family HMM PF00328; glucose-1-phosphatase/inositol phosphatase 1248971..1250212 Escherichia coli O157:H7 str. EC4115 6967862 YP_002269729.1 CDS ECH74115_1241 NC_011353.1 1250250 1250477 R hypothetical protein complement(1250250..1250477) Escherichia coli O157:H7 str. EC4115 6966903 YP_002269730.1 CDS wrbA NC_011353.1 1250498 1251094 R stationary phase that binds TrpR repressor; TrpR binding protein WrbA complement(1250498..1251094) Escherichia coli O157:H7 str. EC4115 6968786 YP_002269731.1 CDS ECH74115_1243 NC_011353.1 1251656 1252984 R identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03616; purine permease ycdG complement(1251656..1252984) Escherichia coli O157:H7 str. EC4115 6968498 YP_002269732.1 CDS ECH74115_1244 NC_011353.1 1253005 1253499 R identified by match to protein family HMM PF01613; match to protein family HMM TIGR03615; flavin reductase rutF complement(1253005..1253499) Escherichia coli O157:H7 str. EC4115 6967852 YP_002269733.1 CDS ECH74115_1245 NC_011353.1 1253510 1254100 R identified by match to protein family HMM PF00881; hypothetical protein complement(1253510..1254100) Escherichia coli O157:H7 str. EC4115 6968819 YP_002269734.1 CDS ECH74115_1246 NC_011353.1 1254110 1254910 R identified by match to protein family HMM PF00561; match to protein family HMM TIGR03611; rutD protein complement(1254110..1254910) Escherichia coli O157:H7 str. EC4115 6969119 YP_002269735.1 CDS ECH74115_1248 NC_011353.1 1255269 1255964 R identified by match to protein family HMM PF00857; match to protein family HMM TIGR03614; isochorismatase family protein, rutB complement(1255269..1255964) Escherichia coli O157:H7 str. EC4115 6969502 YP_002269736.1 CDS ECH74115_1249 NC_011353.1 1255961 1257052 R identified by match to protein family HMM PF00296; match to protein family HMM TIGR03612; monooxygenase rutA complement(1255961..1257052) Escherichia coli O157:H7 str. EC4115 6972129 YP_002269737.1 CDS rutR NC_011353.1 1257340 1257978 D identified by match to protein family HMM PF00440; match to protein family HMM PF08362; match to protein family HMM TIGR03613; transcriptional regulator RutR 1257340..1257978 Escherichia coli O157:H7 str. EC4115 6969699 YP_002269738.1 CDS putA NC_011353.1 1258018 1261980 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1258018..1261980) Escherichia coli O157:H7 str. EC4115 6970285 YP_002269739.1 CDS putP NC_011353.1 1262403 1263911 D identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; sodium/proline symporter 1262403..1263911 Escherichia coli O157:H7 str. EC4115 6967057 YP_002269740.1 CDS ECH74115_1255 NC_011353.1 1265547 1265693 R identified by glimmer; hypothetical protein complement(1265547..1265693) Escherichia coli O157:H7 str. EC4115 6971508 YP_002269741.1 CDS ECH74115_1256 NC_011353.1 1265981 1266112 D hypothetical protein 1265981..1266112 Escherichia coli O157:H7 str. EC4115 6971760 YP_002269742.1 CDS ECH74115_1257 NC_011353.1 1266403 1266549 R hypothetical protein complement(1266403..1266549) Escherichia coli O157:H7 str. EC4115 6969419 YP_002269743.1 CDS ECH74115_1258 NC_011353.1 1266585 1267415 D identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145; iron permease FTR1 family protein 1266585..1267415 Escherichia coli O157:H7 str. EC4115 6968482 YP_002269744.1 CDS ECH74115_1259 NC_011353.1 1267473 1268600 D identified by match to protein family HMM PF09375; hypothetical protein 1267473..1268600 Escherichia coli O157:H7 str. EC4115 6969355 YP_002269745.1 CDS ECH74115_1260 NC_011353.1 1268606 1269877 D identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; Tat-translocated enzyme 1268606..1269877 Escherichia coli O157:H7 str. EC4115 6970515 YP_002269746.1 CDS ECH74115_1261 NC_011353.1 1269944 1270063 R identified by glimmer; hypothetical protein complement(1269944..1270063) Escherichia coli O157:H7 str. EC4115 6970082 YP_002269747.1 CDS phoH NC_011353.1 1270221 1271285 D identified by match to protein family HMM PF02562; hypothetical protein 1270221..1271285 Escherichia coli O157:H7 str. EC4115 6971065 YP_002269748.1 CDS pgaD NC_011353.1 1271335 1271748 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein complement(1271335..1271748) Escherichia coli O157:H7 str. EC4115 6971323 YP_002269749.1 CDS pgaC NC_011353.1 1271750 1272988 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1271750..1272988) Escherichia coli O157:H7 str. EC4115 6967460 YP_002269750.1 CDS pgaB NC_011353.1 1273068 1275086 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1273068..1275086) Escherichia coli O157:H7 str. EC4115 6966846 YP_002269751.1 CDS pgaA NC_011353.1 1275095 1277518 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1275095..1277518) Escherichia coli O157:H7 str. EC4115 6968718 YP_002269752.1 CDS ECH74115_1267 NC_011353.1 1278033 1279463 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1278033..1279463 Escherichia coli O157:H7 str. EC4115 6968083 YP_002269753.1 CDS ECH74115_1268 NC_011353.1 1279657 1281171 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 1279657..1281171 Escherichia coli O157:H7 str. EC4115 6971378 YP_002269754.1 CDS ECH74115_1269 NC_011353.1 1281273 1281764 R hypothetical protein complement(1281273..1281764) Escherichia coli O157:H7 str. EC4115 6970228 YP_002269755.1 CDS ECH74115_1270 NC_011353.1 1281769 1282581 R identified by match to protein family HMM PF00486; transcriptional regulator complement(1281769..1282581) Escherichia coli O157:H7 str. EC4115 6971516 YP_002269756.1 CDS ECH74115_1271 NC_011353.1 1283269 1284051 D identified by match to protein family HMM PF00106; match to protein family HMM PF01370; 2-deoxy-D-gluconate 3-dehydrogenase 1283269..1284051 Escherichia coli O157:H7 str. EC4115 6970552 YP_002269757.1 CDS ECH74115_1272 NC_011353.1 1284197 1284886 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone complement(1284197..1284886) Escherichia coli O157:H7 str. EC4115 6967279 YP_002269758.1 CDS ECH74115_1273 NC_011353.1 1284883 1286067 R outer membrane protein complement(1284883..1286067) Escherichia coli O157:H7 str. EC4115 6966656 YP_002269759.1 CDS ECH74115_1276 NC_011353.1 1288803 1289504 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone complement(1288803..1289504) Escherichia coli O157:H7 str. EC4115 6970796 YP_002269760.1 CDS ECH74115_1277 NC_011353.1 1289590 1290150 R identified by match to protein family HMM PF00419; fimbrial protein complement(1289590..1290150) Escherichia coli O157:H7 str. EC4115 6970001 YP_002269761.1 CDS ECH74115_1278 NC_011353.1 1290193 1290570 R hypothetical protein complement(1290193..1290570) Escherichia coli O157:H7 str. EC4115 6966752 YP_002269762.1 CDS ECH74115_1279 NC_011353.1 1291158 1291304 D identified by glimmer; hypothetical protein 1291158..1291304 Escherichia coli O157:H7 str. EC4115 6971279 YP_002269763.1 CDS ECH74115_1280 NC_011353.1 1291998 1292150 D identified by glimmer; hypothetical protein 1291998..1292150 Escherichia coli O157:H7 str. EC4115 6967611 YP_002269764.1 CDS ECH74115_1281 NC_011353.1 1292207 1296019 D identified by match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01731; match to protein family HMM TIGR01901; hypothetical protein 1292207..1296019 Escherichia coli O157:H7 str. EC4115 6970364 YP_002269765.1 CDS ECH74115_1282 NC_011353.1 1296108 1297727 D identified by match to protein family HMM PF03865; match to protein family HMM PF08479; hemolysin activator-like protein 1296108..1297727 Escherichia coli O157:H7 str. EC4115 6970961 YP_002269766.1 CDS acpS NC_011353.1 1297743 1298111 D identified by match to protein family HMM PF01648; match to protein family HMM TIGR00516; match to protein family HMM TIGR00556; holo-(acyl-carrier-protein) synthase 1297743..1298111 Escherichia coli O157:H7 str. EC4115 6968598 YP_002269767.1 CDS ECH74115_1284 NC_011353.1 1298131 1298886 D identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08659; short chain dehydrogenase/reductase family oxidoreductase 1298131..1298886 Escherichia coli O157:H7 str. EC4115 6969202 YP_002269768.1 CDS ECH74115_1285 NC_011353.1 1298890 1299438 D identified by match to protein family HMM PF07977; hypothetical protein 1298890..1299438 Escherichia coli O157:H7 str. EC4115 6967758 YP_002269769.1 CDS ECH74115_1286 NC_011353.1 1299469 1299741 D acyl-carrier protein 1299469..1299741 Escherichia coli O157:H7 str. EC4115 6968445 YP_002269770.1 CDS ECH74115_1287 NC_011353.1 1299777 1300937 D identified by match to protein family HMM PF01571; match to protein family HMM PF08669; aminomethyltransferase 1299777..1300937 Escherichia coli O157:H7 str. EC4115 6971925 YP_002269771.1 CDS ECH74115_1288 NC_011353.1 1301011 1303569 D identified by match to protein family HMM PF00109; match to protein family HMM PF02801; beta-ketoacyl synthase domain-containing protein 1301011..1303569 Escherichia coli O157:H7 str. EC4115 6966743 YP_002269772.1 CDS ECH74115_1289 NC_011353.1 1303574 1304797 D identified by match to protein family HMM PF00109; match to protein family HMM PF02801; beta-ketoacyl synthase domain-containing protein 1303574..1304797 Escherichia coli O157:H7 str. EC4115 6969290 YP_002269773.1 CDS ECH74115_1290 NC_011353.1 1304794 1305747 D hypothetical protein 1304794..1305747 Escherichia coli O157:H7 str. EC4115 6969198 YP_002269774.1 CDS ECH74115_1291 NC_011353.1 1305758 1306465 D identified by match to protein family HMM PF00005; lipoprotein-releasing system ATP-binding protein LolD 1305758..1306465 Escherichia coli O157:H7 str. EC4115 6970504 YP_002269775.1 CDS ECH74115_1292 NC_011353.1 1306449 1307105 D hypothetical protein 1306449..1307105 Escherichia coli O157:H7 str. EC4115 6970045 YP_002269776.1 CDS ECH74115_1293 NC_011353.1 1307106 1308416 D identified by match to protein family HMM PF02687; efflux ABC transporter permease 1307106..1308416 Escherichia coli O157:H7 str. EC4115 6972109 YP_002269777.1 CDS ECH74115_1294 NC_011353.1 1308425 1309213 D hypothetical protein 1308425..1309213 Escherichia coli O157:H7 str. EC4115 6971672 YP_002269778.1 CDS ECH74115_1295 NC_011353.1 1309210 1310598 D hypothetical protein 1309210..1310598 Escherichia coli O157:H7 str. EC4115 6967395 YP_002269779.1 CDS fabD NC_011353.1 1310609 1311553 D identified by match to protein family HMM PF00698; malonyl CoA-acyl carrier protein transacylase 1310609..1311553 Escherichia coli O157:H7 str. EC4115 6966598 YP_002269780.1 CDS ECH74115_1297 NC_011353.1 1311550 1312536 D hypothetical protein 1311550..1312536 Escherichia coli O157:H7 str. EC4115 6968998 YP_002269781.1 CDS ECH74115_1298 NC_011353.1 1312903 1314105 D identified by match to protein family HMM PF00589; integrase 1312903..1314105 Escherichia coli O157:H7 str. EC4115 6968240 YP_002269782.1 CDS ECH74115_1299 NC_011353.1 1314292 1316109 R identified by glimmer; hypothetical protein complement(1314292..1316109) Escherichia coli O157:H7 str. EC4115 6969624 YP_002269783.1 CDS ECH74115_1301 NC_011353.1 1317122 1317241 R identified by glimmer; hypothetical protein complement(1317122..1317241) Escherichia coli O157:H7 str. EC4115 6968040 YP_002269784.1 CDS ECH74115_1302 NC_011353.1 1318160 1319545 D hypothetical protein 1318160..1319545 Escherichia coli O157:H7 str. EC4115 6968636 YP_002269785.1 CDS ECH74115_1303 NC_011353.1 1320441 1321328 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(1320441..1321328) Escherichia coli O157:H7 str. EC4115 6969640 YP_002269786.1 CDS ECH74115_1304 NC_011353.1 1321328 1321654 R overlaps another CDS with the same product name; IS629, transposase orfA complement(1321328..1321654) Escherichia coli O157:H7 str. EC4115 6968829 YP_002269787.1 CDS ECH74115_1305 NC_011353.1 1321715 1322242 D hypothetical protein 1321715..1322242 Escherichia coli O157:H7 str. EC4115 6967717 YP_002269788.1 CDS ECH74115_1306 NC_011353.1 1322397 1324757 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01896; match to protein family HMM PF04851; type III restriction enzyme, res subunit family 1322397..1324757 Escherichia coli O157:H7 str. EC4115 6971410 YP_002269789.1 CDS ECH74115_1307 NC_011353.1 1324919 1325095 R hypothetical protein complement(1324919..1325095) Escherichia coli O157:H7 str. EC4115 6968944 YP_002269790.1 CDS ECH74115_1308 NC_011353.1 1325514 1327052 R identified by match to protein family HMM PF03050; IS66 family element, transposase complement(1325514..1327052) Escherichia coli O157:H7 str. EC4115 6966956 YP_002269791.1 CDS ECH74115_1309 NC_011353.1 1327102 1327449 R identified by match to protein family HMM PF05717; IS66 family element, orf2 complement(1327102..1327449) Escherichia coli O157:H7 str. EC4115 6970210 YP_002269792.1 CDS ECH74115_1310 NC_011353.1 1327446 1327607 R IS66 family element, orf1 complement(1327446..1327607) Escherichia coli O157:H7 str. EC4115 6970215 YP_002269793.1 CDS ECH74115_1311 NC_011353.1 1327902 1328213 R transposase InsI for insertion sequence element IS30B/C/D complement(1327902..1328213) Escherichia coli O157:H7 str. EC4115 6969378 YP_002269794.1 CDS ECH74115_1312 NC_011353.1 1328353 1329171 D identified by match to protein family HMM PF00665; ISSd1, transposase orfB 1328353..1329171 Escherichia coli O157:H7 str. EC4115 6969388 YP_002269795.1 CDS ECH74115_1313 NC_011353.1 1329284 1329823 D identified by match to protein family HMM PF05818; complement resistance protein 1329284..1329823 Escherichia coli O157:H7 str. EC4115 6967637 YP_002269796.1 CDS ECH74115_1316 NC_011353.1 1330905 1331075 D identified by glimmer; hypothetical protein 1330905..1331075 Escherichia coli O157:H7 str. EC4115 6971185 YP_002269797.1 CDS ECH74115_1317 NC_011353.1 1331122 1331481 D identified by match to protein family HMM PF01219; diacylglycerol kinase 1331122..1331481 Escherichia coli O157:H7 str. EC4115 6968814 YP_002269798.1 CDS ECH74115_1318 NC_011353.1 1331574 1333193 R identified by match to protein family HMM PF00884; match to protein family HMM PF08019; integral membrane protein complement(1331574..1333193) Escherichia coli O157:H7 str. EC4115 6969999 YP_002269799.1 CDS ECH74115_1319 NC_011353.1 1333907 1334026 D identified by glimmer; hypothetical protein 1333907..1334026 Escherichia coli O157:H7 str. EC4115 6968242 YP_002269800.1 CDS ureA NC_011353.1 1334863 1335165 D UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1334863..1335165 Escherichia coli O157:H7 str. EC4115 6968485 YP_002269801.1 CDS ureB NC_011353.1 1335174 1335494 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 1335174..1335494 Escherichia coli O157:H7 str. EC4115 6969336 YP_002269802.1 CDS ureC NC_011353.1 1335487 1337190 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1335487..1337190 Escherichia coli O157:H7 str. EC4115 6967007 YP_002269803.1 CDS ureE NC_011353.1 1337200 1337664 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1337200..1337664 Escherichia coli O157:H7 str. EC4115 6967740 YP_002269804.1 CDS ECH74115_1325 NC_011353.1 1337665 1338339 D identified by match to protein family HMM PF01730; UreF 1337665..1338339 Escherichia coli O157:H7 str. EC4115 6971114 YP_002269805.1 CDS ureG NC_011353.1 1338351 1338968 D identified by match to protein family HMM PF02492; match to protein family HMM TIGR00101; urease accessory protein UreG 1338351..1338968 Escherichia coli O157:H7 str. EC4115 6971608 YP_002269806.1 CDS ECH74115_1327 NC_011353.1 1339016 1339141 R serine proteAse eata complement(1339016..1339141) Escherichia coli O157:H7 str. EC4115 6969535 YP_002269807.1 CDS ECH74115_1328 NC_011353.1 1339224 1339565 R identified by match to protein family HMM PF01527; transposase family protein complement(1339224..1339565) Escherichia coli O157:H7 str. EC4115 6971426 YP_002269808.1 CDS ECH74115_1329 NC_011353.1 1339627 1339755 R TraT complement(1339627..1339755) Escherichia coli O157:H7 str. EC4115 6970540 YP_002269809.1 CDS rpmE2 NC_011353.1 1340180 1340443 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1340180..1340443 Escherichia coli O157:H7 str. EC4115 6968772 YP_002269810.1 CDS ECH74115_1331 NC_011353.1 1340745 1340885 D hypothetical protein 1340745..1340885 Escherichia coli O157:H7 str. EC4115 6970933 YP_002269811.1 CDS ECH74115_1332 NC_011353.1 1341317 1341451 R identified by glimmer; hypothetical protein complement(1341317..1341451) Escherichia coli O157:H7 str. EC4115 6971581 YP_002269812.1 CDS ECH74115_1333 NC_011353.1 1341757 1342428 R hypothetical protein complement(1341757..1342428) Escherichia coli O157:H7 str. EC4115 6969697 YP_002269813.1 CDS ECH74115_1334 NC_011353.1 1342833 1342967 D identified by glimmer; hypothetical protein 1342833..1342967 Escherichia coli O157:H7 str. EC4115 6970365 YP_002269814.1 CDS ECH74115_1335 NC_011353.1 1343448 1343621 R hypothetical protein complement(1343448..1343621) Escherichia coli O157:H7 str. EC4115 6968454 YP_002269815.1 CDS ECH74115_1336 NC_011353.1 1343961 1344578 R ISSfl3 OrfC complement(1343961..1344578) Escherichia coli O157:H7 str. EC4115 6969112 YP_002269816.1 CDS ECH74115_1337 NC_011353.1 1344829 1345191 D identified by match to protein family HMM PF01527; transposase OrfA, ISEc8 1344829..1345191 Escherichia coli O157:H7 str. EC4115 6967084 YP_002269817.1 CDS ECH74115_1338 NC_011353.1 1345188 1345538 D identified by match to protein family HMM PF05717; IS66 family element, orf2 1345188..1345538 Escherichia coli O157:H7 str. EC4115 6968041 YP_002269818.1 CDS ECH74115_1339 NC_011353.1 1345569 1347182 D identified by match to protein family HMM PF03050; IS66 family element, transposase 1345569..1347182 Escherichia coli O157:H7 str. EC4115 6969663 YP_002269819.1 CDS ECH74115_1340 NC_011353.1 1347186 1348043 R identified by match to protein family HMM PF03050; ISSfl3 OrfC complement(1347186..1348043) Escherichia coli O157:H7 str. EC4115 6966984 YP_002269820.1 CDS ECH74115_1342 NC_011353.1 1348453 1348782 R hypothetical protein complement(1348453..1348782) Escherichia coli O157:H7 str. EC4115 6971110 YP_002269821.1 CDS ECH74115_1343 NC_011353.1 1349043 1349510 R TerW protein complement(1349043..1349510) Escherichia coli O157:H7 str. EC4115 6970229 YP_002269822.1 CDS ECH74115_1344 NC_011353.1 1349528 1350736 R hypothetical protein complement(1349528..1350736) Escherichia coli O157:H7 str. EC4115 6972137 YP_002269823.1 CDS ECH74115_1345 NC_011353.1 1350747 1351703 R ATP/GTP-binding protein complement(1350747..1351703) Escherichia coli O157:H7 str. EC4115 6968576 YP_002269824.1 CDS ECH74115_1346 NC_011353.1 1351703 1352782 R hypothetical protein complement(1351703..1352782) Escherichia coli O157:H7 str. EC4115 6967939 YP_002269825.1 CDS ECH74115_1347 NC_011353.1 1352784 1353557 R hypothetical protein complement(1352784..1353557) Escherichia coli O157:H7 str. EC4115 6967346 YP_002269826.1 CDS ECH74115_1348 NC_011353.1 1353550 1354692 R hypothetical protein complement(1353550..1354692) Escherichia coli O157:H7 str. EC4115 6968959 YP_002269827.1 CDS ECH74115_1349 NC_011353.1 1354702 1355760 R identified by match to protein family HMM PF02655; ATP-grasp domain-containing protein complement(1354702..1355760) Escherichia coli O157:H7 str. EC4115 6971026 YP_002269828.1 CDS ECH74115_1350 NC_011353.1 1356083 1356664 D identified by match to protein family HMM PF02342; tellurium resistance protein TerZ 1356083..1356664 Escherichia coli O157:H7 str. EC4115 6970732 YP_002269829.1 CDS ECH74115_1351 NC_011353.1 1356664 1357821 D identified by match to protein family HMM PF02342; protein TerA 1356664..1357821 Escherichia coli O157:H7 str. EC4115 6968489 YP_002269830.1 CDS ECH74115_1352 NC_011353.1 1357844 1358299 D identified by match to protein family HMM PF05099; protein TerB 1357844..1358299 Escherichia coli O157:H7 str. EC4115 6969138 YP_002269831.1 CDS ECH74115_1353 NC_011353.1 1358322 1359362 D identified by match to protein family HMM PF03741; tellurium resistance protein TerC 1358322..1359362 Escherichia coli O157:H7 str. EC4115 6967010 YP_002269832.1 CDS ECH74115_1354 NC_011353.1 1359411 1359989 D identified by match to protein family HMM PF02342; tellurium resistance protein TerD 1359411..1359989 Escherichia coli O157:H7 str. EC4115 6968140 YP_002269833.1 CDS ECH74115_1355 NC_011353.1 1360058 1360633 D identified by match to protein family HMM PF02342; tellurite resistance 1360058..1360633 Escherichia coli O157:H7 str. EC4115 6967357 YP_002269834.1 CDS ECH74115_1356 NC_011353.1 1361055 1361441 D protein TerF 1361055..1361441 Escherichia coli O157:H7 str. EC4115 6968629 YP_002269835.1 CDS ECH74115_1357 NC_011353.1 1361955 1364045 R IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein complement(1361955..1364045) Escherichia coli O157:H7 str. EC4115 6971897 YP_002269836.1 CDS ECH74115_1358 NC_011353.1 1363984 1364166 D identified by glimmer; hypothetical protein 1363984..1364166 Escherichia coli O157:H7 str. EC4115 6967232 YP_002269837.1 CDS ECH74115_1360 NC_011353.1 1366155 1366283 R identified by glimmer; hypothetical protein complement(1366155..1366283) Escherichia coli O157:H7 str. EC4115 6967916 YP_002269838.1 CDS ECH74115_1363 NC_011353.1 1367392 1367511 D identified by glimmer; hypothetical protein 1367392..1367511 Escherichia coli O157:H7 str. EC4115 6969903 YP_002269839.1 CDS ECH74115_1362 NC_011353.1 1367465 1367659 R hypothetical protein complement(1367465..1367659) Escherichia coli O157:H7 str. EC4115 6968297 YP_002269840.1 CDS ECH74115_1364 NC_011353.1 1368138 1368251 D hypothetical protein 1368138..1368251 Escherichia coli O157:H7 str. EC4115 6970351 YP_002269841.1 CDS ECH74115_1365 NC_011353.1 1368256 1368369 R identified by glimmer; hypothetical protein complement(1368256..1368369) Escherichia coli O157:H7 str. EC4115 6968948 YP_002269842.1 CDS ECH74115_1369 NC_011353.1 1369743 1370867 D identified by match to protein family HMM PF06722; glycosyl transferase family protein 1369743..1370867 Escherichia coli O157:H7 str. EC4115 6968114 YP_002269843.1 CDS ECH74115_1370 NC_011353.1 1371009 1371155 R MchS1 protein complement(1371009..1371155) Escherichia coli O157:H7 str. EC4115 6970758 YP_002269844.1 CDS ECH74115_1371 NC_011353.1 1371286 1371789 R identified by match to protein family HMM PF03400; IS1, transposase orfB complement(1371286..1371789) Escherichia coli O157:H7 str. EC4115 6969798 YP_002269845.1 CDS ECH74115_1372 NC_011353.1 1372221 1372679 R hypothetical protein complement(1372221..1372679) Escherichia coli O157:H7 str. EC4115 6968430 YP_002269846.1 CDS ECH74115_1373 NC_011353.1 1373362 1373478 R identified by glimmer; hypothetical protein complement(1373362..1373478) Escherichia coli O157:H7 str. EC4115 6970277 YP_002269847.1 CDS ECH74115_1374 NC_011353.1 1373455 1373646 D hypothetical protein 1373455..1373646 Escherichia coli O157:H7 str. EC4115 6966588 YP_002269848.1 CDS ECH74115_1375 NC_011353.1 1373735 1374358 D hypothetical protein 1373735..1374358 Escherichia coli O157:H7 str. EC4115 6968795 YP_002269849.1 CDS ECH74115_1376 NC_011353.1 1374454 1374687 D hypothetical protein 1374454..1374687 Escherichia coli O157:H7 str. EC4115 6968914 YP_002269850.1 CDS ECH74115_1377 NC_011353.1 1374740 1374931 R hypothetical protein complement(1374740..1374931) Escherichia coli O157:H7 str. EC4115 6968104 YP_002269851.1 CDS ECH74115_1378 NC_011353.1 1375159 1375281 D identified by glimmer; hypothetical protein 1375159..1375281 Escherichia coli O157:H7 str. EC4115 6967258 YP_002269852.1 CDS ECH74115_1379 NC_011353.1 1375525 1376412 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(1375525..1376412) Escherichia coli O157:H7 str. EC4115 6967872 YP_002269853.1 CDS ECH74115_1380 NC_011353.1 1376412 1376738 R overlaps another CDS with the same product name; IS629, transposase orfA complement(1376412..1376738) Escherichia coli O157:H7 str. EC4115 6968254 YP_002269854.1 CDS ECH74115_1381 NC_011353.1 1376901 1377965 D identified by match to protein family HMM PF08479; match to protein family HMM TIGR01731; potra domain, shlb-type family 1376901..1377965 Escherichia coli O157:H7 str. EC4115 6968450 YP_002269855.1 CDS ECH74115_1384 NC_011353.1 1381031 1381159 R identified by glimmer; hypothetical protein complement(1381031..1381159) Escherichia coli O157:H7 str. EC4115 6969931 YP_002269856.1 CDS ECH74115_1385 NC_011353.1 1381387 1382619 D identified by match to protein family HMM PF01507; IbrA 1381387..1382619 Escherichia coli O157:H7 str. EC4115 6970211 YP_002269857.1 CDS ECH74115_1386 NC_011353.1 1382604 1383242 D identified by match to protein family HMM PF02195; immunoglobulin-binding regulator B-like protein 1382604..1383242 Escherichia coli O157:H7 str. EC4115 6968368 YP_002269858.1 CDS ECH74115_1387 NC_011353.1 1383321 1383590 D identified by match to protein family HMM PF06069; LdaB 1383321..1383590 Escherichia coli O157:H7 str. EC4115 6969287 YP_002269859.1 CDS ECH74115_1388 NC_011353.1 1383614 1384255 D hypothetical protein 1383614..1384255 Escherichia coli O157:H7 str. EC4115 6967472 YP_002269860.1 CDS ECH74115_1390 NC_011353.1 1384953 1385201 R transposase complement(1384953..1385201) Escherichia coli O157:H7 str. EC4115 6969997 YP_002269861.1 CDS ECH74115_1391 NC_011353.1 1385318 1385680 D identified by match to protein family HMM PF01527; IS66 family element, orf1 1385318..1385680 Escherichia coli O157:H7 str. EC4115 6970268 YP_002269862.1 CDS ECH74115_1392 NC_011353.1 1385980 1386162 R hypothetical protein complement(1385980..1386162) Escherichia coli O157:H7 str. EC4115 6967600 YP_002269863.1 CDS ECH74115_1393 NC_011353.1 1386492 1387364 D identified by match to protein family HMM PF01926; GTPase 1386492..1387364 Escherichia coli O157:H7 str. EC4115 6968585 YP_002269864.1 CDS ECH74115_1395 NC_011353.1 1387736 1390585 D identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; pertactin family protein 1387736..1390585 Escherichia coli O157:H7 str. EC4115 6967004 YP_002269865.1 CDS ECH74115_1396 NC_011353.1 1390696 1393080 D hypothetical protein 1390696..1393080 Escherichia coli O157:H7 str. EC4115 6970149 YP_002269866.1 CDS ECH74115_1397 NC_011353.1 1393077 1393982 D hypothetical protein 1393077..1393982 Escherichia coli O157:H7 str. EC4115 6971133 YP_002269867.1 CDS ECH74115_1398 NC_011353.1 1393991 1395049 D identified by match to protein family HMM PF01734; phospholipase, patatin family 1393991..1395049 Escherichia coli O157:H7 str. EC4115 6969206 YP_002269868.1 CDS ECH74115_1399 NC_011353.1 1395154 1395318 R hypothetical protein complement(1395154..1395318) Escherichia coli O157:H7 str. EC4115 6969500 YP_002269869.1 CDS ECH74115_1400 NC_011353.1 1395389 1396207 D identified by match to protein family HMM PF06067; hypothetical protein 1395389..1396207 Escherichia coli O157:H7 str. EC4115 6966905 YP_002269870.1 CDS ECH74115_1401 NC_011353.1 1396298 1396783 D identified by match to protein family HMM PF03230; antirestriction protein 1396298..1396783 Escherichia coli O157:H7 str. EC4115 6967658 YP_002269871.1 CDS ECH74115_1402 NC_011353.1 1396799 1397275 D identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; DNA repair protein, RadC family 1396799..1397275 Escherichia coli O157:H7 str. EC4115 6968619 YP_002269872.1 CDS ECH74115_1403 NC_011353.1 1397338 1397559 D identified by match to protein family HMM PF06174; hypothetical protein 1397338..1397559 Escherichia coli O157:H7 str. EC4115 6969273 YP_002269873.1 CDS ECH74115_1404 NC_011353.1 1397559 1397672 D hypothetical protein 1397559..1397672 Escherichia coli O157:H7 str. EC4115 6970263 YP_002269874.1 CDS ECH74115_1405 NC_011353.1 1397797 1398096 D identified by match to protein family HMM PF06154; antitoxin module of toxin-antitoxin system 1397797..1398096 Escherichia coli O157:H7 str. EC4115 6968224 YP_002269875.1 CDS ECH74115_1406 NC_011353.1 1398143 1398517 D identified by match to protein family HMM PF06755; hypothetical protein 1398143..1398517 Escherichia coli O157:H7 str. EC4115 6969928 YP_002269876.1 CDS ECH74115_1407 NC_011353.1 1398514 1399005 D hypothetical protein 1398514..1399005 Escherichia coli O157:H7 str. EC4115 6972067 YP_002269877.1 CDS ECH74115_1408 NC_011353.1 1399017 1399214 D identified by match to protein family HMM PF06117; hypothetical protein 1399017..1399214 Escherichia coli O157:H7 str. EC4115 6968340 YP_002269878.1 CDS ECH74115_1409 NC_011353.1 1399299 1400141 D hypothetical protein 1399299..1400141 Escherichia coli O157:H7 str. EC4115 6970320 YP_002269879.1 CDS ECH74115_1411 NC_011353.1 1400612 1401550 D identified by match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase family protein 1400612..1401550 Escherichia coli O157:H7 str. EC4115 6972412 YP_002269880.1 CDS ECH74115_1412 NC_011353.1 1401605 1402342 D identified by match to protein family HMM PF02811; hydrolase 1401605..1402342 Escherichia coli O157:H7 str. EC4115 6970921 YP_002269881.1 CDS ECH74115_1413 NC_011353.1 1402366 1402920 D identified by match to protein family HMM PF06192; chaperone, TorD family 1402366..1402920 Escherichia coli O157:H7 str. EC4115 6970305 YP_002269882.1 CDS ECH74115_1414 NC_011353.1 1402937 1403059 R identified by glimmer; hypothetical protein complement(1402937..1403059) Escherichia coli O157:H7 str. EC4115 6969653 YP_002269883.1 CDS ECH74115_1415 NC_011353.1 1403022 1403513 D identified by match to protein family HMM PF06496; hypothetical protein 1403022..1403513 Escherichia coli O157:H7 str. EC4115 6968440 YP_002269884.1 CDS csgG NC_011353.1 1403577 1404410 R identified by match to protein family HMM PF03783; curli production assembly/transport subunit CsgG complement(1403577..1404410) Escherichia coli O157:H7 str. EC4115 6970720 YP_002269885.1 CDS csgF NC_011353.1 1404437 1404853 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1404437..1404853) Escherichia coli O157:H7 str. EC4115 6967020 YP_002269886.1 CDS csgE NC_011353.1 1404878 1405267 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1404878..1405267) Escherichia coli O157:H7 str. EC4115 6969258 YP_002269887.1 CDS csgD NC_011353.1 1405272 1405922 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1405272..1405922) Escherichia coli O157:H7 str. EC4115 6970987 YP_002269888.1 CDS ECH74115_1420 NC_011353.1 1405905 1406036 D identified by glimmer; hypothetical protein 1405905..1406036 Escherichia coli O157:H7 str. EC4115 6967370 YP_002269889.1 CDS csgB NC_011353.1 1406649 1407131 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1406649..1407131 Escherichia coli O157:H7 str. EC4115 6971637 YP_002269890.1 CDS csgA NC_011353.1 1407172 1407630 D identified by match to protein family HMM PF07012; cryptic curlin major subunit 1407172..1407630 Escherichia coli O157:H7 str. EC4115 6969716 YP_002269891.1 CDS csgC NC_011353.1 1407689 1408021 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1407689..1408021 Escherichia coli O157:H7 str. EC4115 6970763 YP_002269892.1 CDS ECH74115_1424 NC_011353.1 1408142 1408453 D hypothetical protein 1408142..1408453 Escherichia coli O157:H7 str. EC4115 6967946 YP_002269893.1 CDS ECH74115_1425 NC_011353.1 1408548 1409081 D identified by match to protein family HMM PF01661; hypothetical protein 1408548..1409081 Escherichia coli O157:H7 str. EC4115 6969163 YP_002269894.1 CDS ECH74115_1426 NC_011353.1 1409083 1410504 D identified by match to protein family HMM PF00614; phopholipase D 1409083..1410504 Escherichia coli O157:H7 str. EC4115 6967143 YP_002269895.1 CDS mdoC NC_011353.1 1410512 1411669 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1410512..1411669) Escherichia coli O157:H7 str. EC4115 6971015 YP_002269896.1 CDS mdoG NC_011353.1 1412044 1413597 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1412044..1413597 Escherichia coli O157:H7 str. EC4115 6971733 YP_002269897.1 CDS mdoH NC_011353.1 1413620 1416133 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1413620..1416133 Escherichia coli O157:H7 str. EC4115 6969476 YP_002269898.1 CDS ECH74115_1430 NC_011353.1 1416306 1416533 D identified by match to protein family HMM PF07119; hypothetical protein 1416306..1416533 Escherichia coli O157:H7 str. EC4115 6970180 YP_002269899.1 CDS msyB NC_011353.1 1416534 1416908 R hypothetical protein complement(1416534..1416908) Escherichia coli O157:H7 str. EC4115 6971848 YP_002269900.1 CDS lpxL NC_011353.1 1418389 1419309 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1418389..1419309) Escherichia coli O157:H7 str. EC4115 6966943 YP_002269901.1 CDS ECH74115_1434 NC_011353.1 1419534 1420586 D identified by match to protein family HMM PF00581; hypothetical protein 1419534..1420586 Escherichia coli O157:H7 str. EC4115 6968986 YP_002269902.1 CDS yceI NC_011353.1 1420628 1421203 R identified by match to protein family HMM PF04264; hypothetical protein complement(1420628..1421203) Escherichia coli O157:H7 str. EC4115 6968507 YP_002269903.1 CDS ECH74115_1436 NC_011353.1 1421207 1421773 R identified by match to protein family HMM PF01292; nickel-dependent hydrogenase b-type cytochrome subunit complement(1421207..1421773) Escherichia coli O157:H7 str. EC4115 6970643 YP_002269904.1 CDS ECH74115_1437 NC_011353.1 1422034 1422147 R hypothetical protein complement(1422034..1422147) Escherichia coli O157:H7 str. EC4115 6969398 YP_002269905.1 CDS solA NC_011353.1 1422195 1423313 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1422195..1423313) Escherichia coli O157:H7 str. EC4115 6971653 YP_002269906.1 CDS bssS NC_011353.1 1423428 1423685 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1423428..1423685) Escherichia coli O157:H7 str. EC4115 6967836 YP_002269907.1 CDS dinI NC_011353.1 1423972 1424217 R identified by match to protein family HMM PF06183; DNA damage-inducible protein I complement(1423972..1424217) Escherichia coli O157:H7 str. EC4115 6967237 YP_002269908.1 CDS pyrC NC_011353.1 1424291 1425337 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1424291..1425337) Escherichia coli O157:H7 str. EC4115 6969193 YP_002269909.1 CDS ECH74115_1442 NC_011353.1 1425443 1426003 R identified by match to protein family HMM PF07273; hypothetical protein complement(1425443..1426003) Escherichia coli O157:H7 str. EC4115 6968911 YP_002269910.1 CDS grxB NC_011353.1 1426137 1426784 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1426137..1426784) Escherichia coli O157:H7 str. EC4115 6970366 YP_002269911.1 CDS mdtH NC_011353.1 1426848 1428056 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1426848..1428056) Escherichia coli O157:H7 str. EC4115 6969700 YP_002269912.1 CDS rimJ NC_011353.1 1428292 1428876 D identified by match to protein family HMM PF00583; ribosomal-protein-S5-alanine N-acetyltransferase 1428292..1428876 Escherichia coli O157:H7 str. EC4115 6971580 YP_002269913.1 CDS ECH74115_1446 NC_011353.1 1428887 1429534 D identified by match to protein family HMM PF04337; hypothetical protein 1428887..1429534 Escherichia coli O157:H7 str. EC4115 6970896 YP_002269914.1 CDS ECH74115_1447 NC_011353.1 1429536 1430459 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase family, NAD-binding 1429536..1430459 Escherichia coli O157:H7 str. EC4115 6967374 YP_002269915.1 CDS mviN NC_011353.1 1430569 1432104 D identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695; integral membrane protein MviN 1430569..1432104 Escherichia coli O157:H7 str. EC4115 6967207 YP_002269916.1 CDS flgN NC_011353.1 1432144 1432560 R identified by match to protein family HMM PF05130; flagella synthesis protein FlgN complement(1432144..1432560) Escherichia coli O157:H7 str. EC4115 6968963 YP_002269917.1 CDS flgM NC_011353.1 1432565 1432858 R regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1432565..1432858) Escherichia coli O157:H7 str. EC4115 6968096 YP_002269918.1 CDS flgA NC_011353.1 1432934 1433593 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1432934..1433593) Escherichia coli O157:H7 str. EC4115 6970619 YP_002269919.1 CDS flgB NC_011353.1 1433748 1434164 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1433748..1434164 Escherichia coli O157:H7 str. EC4115 6969802 YP_002269920.1 CDS flgC NC_011353.1 1434168 1434572 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1434168..1434572 Escherichia coli O157:H7 str. EC4115 6969751 YP_002269921.1 CDS flgD NC_011353.1 1434584 1435279 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1434584..1435279 Escherichia coli O157:H7 str. EC4115 6972186 YP_002269922.1 CDS flgE NC_011353.1 1435304 1436509 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1435304..1436509 Escherichia coli O157:H7 str. EC4115 6967515 YP_002269923.1 CDS flgF NC_011353.1 1436529 1437284 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1436529..1437284 Escherichia coli O157:H7 str. EC4115 6966858 YP_002269924.1 CDS flgG NC_011353.1 1437422 1438204 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1437422..1438204 Escherichia coli O157:H7 str. EC4115 6968181 YP_002269925.1 CDS flgH NC_011353.1 1438257 1438955 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1438257..1438955 Escherichia coli O157:H7 str. EC4115 6970245 YP_002269926.1 CDS flgI NC_011353.1 1438967 1440064 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1438967..1440064 Escherichia coli O157:H7 str. EC4115 6969444 YP_002269927.1 CDS flgJ NC_011353.1 1440064 1441005 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1440064..1441005 Escherichia coli O157:H7 str. EC4115 6969934 YP_002269928.1 CDS flgK NC_011353.1 1441071 1442714 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1441071..1442714 Escherichia coli O157:H7 str. EC4115 6966982 YP_002269929.1 CDS flgL NC_011353.1 1442726 1443679 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1442726..1443679 Escherichia coli O157:H7 str. EC4115 6967525 YP_002269930.1 CDS rne NC_011353.1 1443874 1447059 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1443874..1447059) Escherichia coli O157:H7 str. EC4115 6966711 YP_002269931.1 CDS rluC NC_011353.1 1447632 1448591 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1447632..1448591 Escherichia coli O157:H7 str. EC4115 6972195 YP_002269932.1 CDS maf2 NC_011353.1 1448692 1449315 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1448692..1449315) Escherichia coli O157:H7 str. EC4115 6971398 YP_002269933.1 CDS rpmF NC_011353.1 1450047 1450220 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1450047..1450220 Escherichia coli O157:H7 str. EC4115 6969254 YP_002269934.1 CDS plsX NC_011353.1 1450301 1451371 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1450301..1451371 Escherichia coli O157:H7 str. EC4115 6969004 YP_002269935.1 CDS fabH NC_011353.1 1451439 1452392 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1451439..1452392 Escherichia coli O157:H7 str. EC4115 6968215 YP_002269936.1 CDS fabD NC_011353.1 1452408 1453337 D identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 1452408..1453337 Escherichia coli O157:H7 str. EC4115 6968620 YP_002269937.1 CDS fabG NC_011353.1 1453350 1454084 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1453350..1454084 Escherichia coli O157:H7 str. EC4115 6969093 YP_002269938.1 CDS acpP NC_011353.1 1454295 1454531 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1454295..1454531 Escherichia coli O157:H7 str. EC4115 6967638 YP_002269939.1 CDS fabF NC_011353.1 1454619 1455860 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1454619..1455860 Escherichia coli O157:H7 str. EC4115 6968659 YP_002269940.1 CDS pabC NC_011353.1 1455980 1456789 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1455980..1456789 Escherichia coli O157:H7 str. EC4115 6972144 YP_002269941.1 CDS ECH74115_1476 NC_011353.1 1456792 1457814 D identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 1456792..1457814 Escherichia coli O157:H7 str. EC4115 6967404 YP_002269942.1 CDS tmk NC_011353.1 1457804 1458445 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1457804..1458445 Escherichia coli O157:H7 str. EC4115 6970272 YP_002269943.1 CDS holB NC_011353.1 1458442 1459446 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1458442..1459446 Escherichia coli O157:H7 str. EC4115 6971394 YP_002269944.1 CDS ECH74115_1479 NC_011353.1 1459457 1460254 D identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; metallodependent hydrolase 1459457..1460254 Escherichia coli O157:H7 str. EC4115 6969357 YP_002269945.1 CDS ptsG NC_011353.1 1460549 1461982 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1460549..1461982 Escherichia coli O157:H7 str. EC4115 6969847 YP_002269946.1 CDS fhuE NC_011353.1 1462042 1464231 R identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; ferric-rhodotorulic acid outer membrane transporter complement(1462042..1464231) Escherichia coli O157:H7 str. EC4115 6969233 YP_002269947.1 CDS ECH74115_1482 NC_011353.1 1464264 1464452 R hypothetical protein complement(1464264..1464452) Escherichia coli O157:H7 str. EC4115 6968366 YP_002269948.1 CDS hinT NC_011353.1 1464583 1464942 D identified by match to protein family HMM PF01230; purine nucleoside phosphoramidase 1464583..1464942 Escherichia coli O157:H7 str. EC4115 6969151 YP_002269949.1 CDS ECH74115_1484 NC_011353.1 1464945 1465322 D identified by match to protein family HMM PF07233; lipoprotein 1464945..1465322 Escherichia coli O157:H7 str. EC4115 6969607 YP_002269950.1 CDS ECH74115_1485 NC_011353.1 1465336 1465977 D identified by match to protein family HMM TIGR02722; lipoprotein 1465336..1465977 Escherichia coli O157:H7 str. EC4115 6970395 YP_002269951.1 CDS thiK NC_011353.1 1465958 1466782 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1465958..1466782 Escherichia coli O157:H7 str. EC4115 6971694 YP_002269952.1 CDS nagZ NC_011353.1 1466793 1467818 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1466793..1467818 Escherichia coli O157:H7 str. EC4115 6966682 YP_002269953.1 CDS ECH74115_1488 NC_011353.1 1467841 1468383 D identified by match to protein family HMM PF05728; hypothetical protein 1467841..1468383 Escherichia coli O157:H7 str. EC4115 6967298 YP_002269954.1 CDS ndh NC_011353.1 1468783 1470087 D identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992; NADH dehydrogenase 1468783..1470087 Escherichia coli O157:H7 str. EC4115 6967778 YP_002269955.1 CDS ECH74115_1490 NC_011353.1 1470314 1470853 D identified by match to protein family HMM PF05433; hypothetical protein 1470314..1470853 Escherichia coli O157:H7 str. EC4115 6969214 YP_002269956.1 CDS ECH74115_1491 NC_011353.1 1470915 1471547 R identified by match to protein family HMM PF00440; TetR family transcriptional regulator complement(1470915..1471547) Escherichia coli O157:H7 str. EC4115 6970022 YP_002269957.1 CDS ECH74115_1492 NC_011353.1 1471788 1472045 D identified by match to protein family HMM PF07338; hypothetical protein 1471788..1472045 Escherichia coli O157:H7 str. EC4115 6968127 YP_002269958.1 CDS ECH74115_1493 NC_011353.1 1472128 1473087 R identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM domain/ErfK/YbiS/YcfS/YnhG family protein complement(1472128..1473087) Escherichia coli O157:H7 str. EC4115 6968940 YP_002269959.1 CDS mfd NC_011353.1 1473234 1476680 R identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor complement(1473234..1476680) Escherichia coli O157:H7 str. EC4115 6969887 YP_002269960.1 CDS ECH74115_1495 NC_011353.1 1476808 1477881 R identified by match to protein family HMM PF01757; acyltransferase complement(1476808..1477881) Escherichia coli O157:H7 str. EC4115 6970516 YP_002269961.1 CDS lolC NC_011353.1 1478143 1479342 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1478143..1479342 Escherichia coli O157:H7 str. EC4115 6971455 YP_002269962.1 CDS lolD NC_011353.1 1479335 1480036 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1479335..1480036 Escherichia coli O157:H7 str. EC4115 6972111 YP_002269963.1 CDS lolE NC_011353.1 1480036 1481280 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1480036..1481280 Escherichia coli O157:H7 str. EC4115 6966867 YP_002269964.1 CDS nagK NC_011353.1 1481309 1482220 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1481309..1482220 Escherichia coli O157:H7 str. EC4115 6968342 YP_002269965.1 CDS npdA NC_011353.1 1482236 1483057 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1482236..1483057 Escherichia coli O157:H7 str. EC4115 6968115 YP_002269966.1 CDS potD NC_011353.1 1483213 1484259 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1483213..1484259) Escherichia coli O157:H7 str. EC4115 6968896 YP_002269967.1 CDS potC NC_011353.1 1484256 1485050 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1484256..1485050) Escherichia coli O157:H7 str. EC4115 6969121 YP_002269968.1 CDS ECH74115_1503 NC_011353.1 1485217 1486335 R identified by match to protein family HMM PF00589; match to protein family HMM PF09003; phage integrase family protein complement(1485217..1486335) Escherichia coli O157:H7 str. EC4115 6968325 YP_002269969.1 CDS ECH74115_1504 NC_011353.1 1486304 1486573 R excisionase complement(1486304..1486573) Escherichia coli O157:H7 str. EC4115 6969687 YP_002269970.1 CDS ECH74115_1505 NC_011353.1 1486635 1486979 R exodeoxyribonuclease VIII complement(1486635..1486979) Escherichia coli O157:H7 str. EC4115 6971766 YP_002269971.1 CDS ECH74115_1506 NC_011353.1 1487157 1487672 D hypothetical protein 1487157..1487672 Escherichia coli O157:H7 str. EC4115 6970982 YP_002269972.1 CDS ECH74115_1507 NC_011353.1 1487787 1488017 R identified by match to protein family HMM PF07151; hypothetical protein complement(1487787..1488017) Escherichia coli O157:H7 str. EC4115 6967870 YP_002269973.1 CDS ECH74115_1508 NC_011353.1 1488255 1488731 R Rac prophage repressor complement(1488255..1488731) Escherichia coli O157:H7 str. EC4115 6967072 YP_002269974.1 CDS ECH74115_1509 NC_011353.1 1489163 1489588 D identified by match to protein family HMM PF06254; hypothetical protein 1489163..1489588 Escherichia coli O157:H7 str. EC4115 6969207 YP_002269975.1 CDS ECH74115_1510 NC_011353.1 1489657 1490694 D hypothetical protein 1489657..1490694 Escherichia coli O157:H7 str. EC4115 6970427 YP_002269976.1 CDS ECH74115_1511 NC_011353.1 1490726 1491148 D hypothetical protein 1490726..1491148 Escherichia coli O157:H7 str. EC4115 6970556 YP_002269977.1 CDS ECH74115_1512 NC_011353.1 1491182 1491898 D identified by match to protein family HMM PF07789; hypothetical protein 1491182..1491898 Escherichia coli O157:H7 str. EC4115 6969295 YP_002269978.1 CDS ECH74115_1513 NC_011353.1 1491958 1492212 D hypothetical protein 1491958..1492212 Escherichia coli O157:H7 str. EC4115 6968484 YP_002269979.1 CDS ECH74115_1514 NC_011353.1 1492215 1492511 D hypothetical protein 1492215..1492511 Escherichia coli O157:H7 str. EC4115 6970546 YP_002269980.1 CDS ECH74115_1515 NC_011353.1 1492501 1492818 D hypothetical protein 1492501..1492818 Escherichia coli O157:H7 str. EC4115 6969881 YP_002269981.1 CDS ECH74115_1516 NC_011353.1 1492967 1493089 D hypothetical protein 1492967..1493089 Escherichia coli O157:H7 str. EC4115 6972119 YP_002269982.1 CDS ECH74115_1517 NC_011353.1 1493076 1493513 D hypothetical protein 1493076..1493513 Escherichia coli O157:H7 str. EC4115 6971460 YP_002269983.1 CDS ECH74115_1518 NC_011353.1 1493515 1493706 D hypothetical protein 1493515..1493706 Escherichia coli O157:H7 str. EC4115 6970822 YP_002269984.1 CDS ECH74115_1519 NC_011353.1 1493709 1494296 D identified by match to protein family HMM PF04448; hypothetical protein 1493709..1494296 Escherichia coli O157:H7 str. EC4115 6967504 YP_002269985.1 CDS ECH74115_1520 NC_011353.1 1494367 1494516 D hypothetical protein 1494367..1494516 Escherichia coli O157:H7 str. EC4115 6968341 YP_002269986.1 CDS ECH74115_1522 NC_011353.1 1495365 1496414 D identified by match to protein family HMM PF06914; hypothetical protein 1495365..1496414 Escherichia coli O157:H7 str. EC4115 6970888 YP_002269987.1 CDS ECH74115_1523 NC_011353.1 1496427 1496684 D identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1496427..1496684 Escherichia coli O157:H7 str. EC4115 6970233 YP_002269988.1 CDS ECH74115_1524 NC_011353.1 1496665 1497957 D identified by match to protein family HMM PF03629; YjhS 1496665..1497957 Escherichia coli O157:H7 str. EC4115 6972139 YP_002269989.1 CDS ECH74115_1525 NC_011353.1 1498105 1498287 D identified by match to protein family HMM PF07125; hypothetical protein 1498105..1498287 Escherichia coli O157:H7 str. EC4115 6968642 YP_002269990.1 CDS ECH74115_1526 NC_011353.1 1498325 1498594 D identified by match to protein family HMM PF05696; hypothetical protein 1498325..1498594 Escherichia coli O157:H7 str. EC4115 6970533 YP_002269991.1 CDS ECH74115_1527 NC_011353.1 1498670 1498885 D identified by match to protein family HMM PF04971; hypothetical protein 1498670..1498885 Escherichia coli O157:H7 str. EC4115 6966996 YP_002269992.1 CDS ECH74115_1528 NC_011353.1 1498890 1499234 D identified by match to protein family HMM PF07041; hypothetical protein 1498890..1499234 Escherichia coli O157:H7 str. EC4115 6968869 YP_002269993.1 CDS ECH74115_1529 NC_011353.1 1499285 1499818 D identified by match to protein family HMM PF00959; phage lysozyme 1499285..1499818 Escherichia coli O157:H7 str. EC4115 6971488 YP_002269994.1 CDS ECH74115_1530 NC_011353.1 1500089 1500658 D anti-repressor protein Ant 1500089..1500658 Escherichia coli O157:H7 str. EC4115 6967683 YP_002269995.1 CDS ECH74115_1531 NC_011353.1 1500658 1500804 D hypothetical protein 1500658..1500804 Escherichia coli O157:H7 str. EC4115 6971857 YP_002269996.1 CDS ECH74115_1532 NC_011353.1 1500812 1501279 D identified by match to protein family HMM PF03245; bacteriophage lysis protein 1500812..1501279 Escherichia coli O157:H7 str. EC4115 6968203 YP_002269997.1 CDS ECH74115_1533 NC_011353.1 1501303 1501527 D hypothetical protein 1501303..1501527 Escherichia coli O157:H7 str. EC4115 6967341 YP_002269998.1 CDS ECH74115_1534 NC_011353.1 1501675 1501797 D identified by glimmer; hypothetical protein 1501675..1501797 Escherichia coli O157:H7 str. EC4115 6966549 YP_002269999.1 CDS ECH74115_1535 NC_011353.1 1501884 1502024 D hypothetical protein 1501884..1502024 Escherichia coli O157:H7 str. EC4115 6971465 YP_002270000.1 CDS ECH74115_1536 NC_011353.1 1502154 1502279 R hypothetical protein complement(1502154..1502279) Escherichia coli O157:H7 str. EC4115 6967735 YP_002270001.1 CDS ECH74115_1537 NC_011353.1 1503036 1503599 D terminase small subunit 1503036..1503599 Escherichia coli O157:H7 str. EC4115 6969796 YP_002270002.1 CDS ECH74115_1538 NC_011353.1 1503596 1505257 D identified by match to protein family HMM PF03354; phage terminase, large subunit 1503596..1505257 Escherichia coli O157:H7 str. EC4115 6971851 YP_002270003.1 CDS ECH74115_1539 NC_011353.1 1505321 1507258 D identified by match to protein family HMM PF04586; prohead protease 1505321..1507258 Escherichia coli O157:H7 str. EC4115 6972176 YP_002270004.1 CDS ECH74115_1540 NC_011353.1 1507470 1509971 D identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 1507470..1509971 Escherichia coli O157:H7 str. EC4115 6971530 YP_002270005.1 CDS ECH74115_1542 NC_011353.1 1510051 1510377 D hypothetical protein 1510051..1510377 Escherichia coli O157:H7 str. EC4115 6967094 YP_002270006.1 CDS ECH74115_1543 NC_011353.1 1510387 1510737 D identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor 1510387..1510737 Escherichia coli O157:H7 str. EC4115 6970206 YP_002270007.1 CDS ECH74115_1544 NC_011353.1 1510734 1511180 D identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 1510734..1511180 Escherichia coli O157:H7 str. EC4115 6968094 YP_002270008.1 CDS ECH74115_1545 NC_011353.1 1511177 1511521 D identified by glimmer; hypothetical protein 1511177..1511521 Escherichia coli O157:H7 str. EC4115 6970524 YP_002270009.1 CDS ECH74115_1547 NC_011353.1 1512318 1512692 D identified by match to protein family HMM PF06222; phage tail assembly chaperone 1512318..1512692 Escherichia coli O157:H7 str. EC4115 6971650 YP_002270010.1 CDS ECH74115_1548 NC_011353.1 1512794 1512997 D identified by glimmer; hypothetical protein 1512794..1512997 Escherichia coli O157:H7 str. EC4115 6970036 YP_002270011.1 CDS ECH74115_1549 NC_011353.1 1513050 1516292 D identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein 1513050..1516292 Escherichia coli O157:H7 str. EC4115 6971405 YP_002270012.1 CDS ECH74115_1550 NC_011353.1 1516285 1516626 D identified by match to protein family HMM PF05939; phage minor tail protein 1516285..1516626 Escherichia coli O157:H7 str. EC4115 6972189 YP_002270013.1 CDS ECH74115_1551 NC_011353.1 1516626 1517324 D identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1516626..1517324 Escherichia coli O157:H7 str. EC4115 6968687 YP_002270014.1 CDS ECH74115_1552 NC_011353.1 1517341 1517481 R regulatory protein complement(1517341..1517481) Escherichia coli O157:H7 str. EC4115 6969921 YP_002270015.1 CDS ECH74115_1553 NC_011353.1 1517675 1517815 D hypothetical protein 1517675..1517815 Escherichia coli O157:H7 str. EC4115 6971995 YP_002270016.1 CDS ECH74115_1555 NC_011353.1 1518118 1518996 D identified by match to protein family HMM PF02498; antirepressor protein 1518118..1518996 Escherichia coli O157:H7 str. EC4115 6972253 YP_002270017.1 CDS ECH74115_1556 NC_011353.1 1519050 1519787 D identified by match to protein family HMM PF00877; tail assembly protein 1519050..1519787 Escherichia coli O157:H7 str. EC4115 6971489 YP_002270018.1 CDS ECH74115_1557 NC_011353.1 1519784 1519969 D bacteriophage lambda tail assembly protein I 1519784..1519969 Escherichia coli O157:H7 str. EC4115 6970534 YP_002270019.1 CDS ECH74115_1558 NC_011353.1 1520091 1522439 D identified by glimmer; hypothetical protein 1520091..1522439 Escherichia coli O157:H7 str. EC4115 6966997 YP_002270020.1 CDS ECH74115_1559 NC_011353.1 1523030 1526431 D identified by glimmer; hypothetical protein 1523030..1526431 Escherichia coli O157:H7 str. EC4115 6971742 YP_002270021.1 CDS ECH74115_1560 NC_011353.1 1526808 1526927 R hypothetical protein complement(1526808..1526927) Escherichia coli O157:H7 str. EC4115 6967368 YP_002270022.1 CDS ECH74115_1561 NC_011353.1 1526974 1527879 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(1526974..1527879) Escherichia coli O157:H7 str. EC4115 6966577 YP_002270023.1 CDS ECH74115_1564 NC_011353.1 1528384 1528512 D transposase 1528384..1528512 Escherichia coli O157:H7 str. EC4115 6969833 YP_002270024.1 CDS ECH74115_1565 NC_011353.1 1529076 1530437 R hypothetical protein complement(1529076..1530437) Escherichia coli O157:H7 str. EC4115 6966561 YP_002270025.1 CDS potB NC_011353.1 1530801 1531664 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1530801..1531664) Escherichia coli O157:H7 str. EC4115 6971408 YP_002270026.1 CDS potA NC_011353.1 1531648 1532784 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1531648..1532784) Escherichia coli O157:H7 str. EC4115 6971381 YP_002270027.1 CDS pepT NC_011353.1 1532992 1534260 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1532992..1534260 Escherichia coli O157:H7 str. EC4115 6972211 YP_002270028.1 CDS ECH74115_1569 NC_011353.1 1534309 1535430 R identified by match to protein family HMM PF08007; cupin family protein complement(1534309..1535430) Escherichia coli O157:H7 str. EC4115 6969029 YP_002270029.1 CDS ECH74115_1570 NC_011353.1 1535510 1535674 R hypothetical protein complement(1535510..1535674) Escherichia coli O157:H7 str. EC4115 6966653 YP_002270030.1 CDS ECH74115_1571 NC_011353.1 1535679 1536908 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 1535679..1536908 Escherichia coli O157:H7 str. EC4115 6968162 YP_002270031.1 CDS ECH74115_1572 NC_011353.1 1537519 1538463 D hypothetical protein 1537519..1538463 Escherichia coli O157:H7 str. EC4115 6968969 YP_002270032.1 CDS ECH74115_1573 NC_011353.1 1538456 1538668 D identified by glimmer; hypothetical protein 1538456..1538668 Escherichia coli O157:H7 str. EC4115 6970683 YP_002270033.1 CDS ECH74115_1575 NC_011353.1 1539115 1539348 D hypothetical protein 1539115..1539348 Escherichia coli O157:H7 str. EC4115 6971817 YP_002270034.1 CDS ECH74115_1576 NC_011353.1 1539354 1539653 D hypothetical protein 1539354..1539653 Escherichia coli O157:H7 str. EC4115 6969743 YP_002270035.1 CDS ECH74115_1577 NC_011353.1 1539650 1541050 D bacteriophage P4 DNA primease 1539650..1541050 Escherichia coli O157:H7 str. EC4115 6970162 YP_002270036.1 CDS ECH74115_1578 NC_011353.1 1541251 1541502 D bacteriophage protein 1541251..1541502 Escherichia coli O157:H7 str. EC4115 6970806 YP_002270037.1 CDS ECH74115_1579 NC_011353.1 1541499 1541909 D identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-strand binding protein 1541499..1541909 Escherichia coli O157:H7 str. EC4115 6971816 YP_002270038.1 CDS ECH74115_1580 NC_011353.1 1542149 1542277 D identified by glimmer; hypothetical protein 1542149..1542277 Escherichia coli O157:H7 str. EC4115 6970995 YP_002270039.1 CDS ECH74115_1582 NC_011353.1 1542795 1543001 D hypothetical protein 1542795..1543001 Escherichia coli O157:H7 str. EC4115 6966894 YP_002270040.1 CDS ECH74115_1583 NC_011353.1 1543001 1544056 D identified by match to protein family HMM PF03864; phage major capsid protein E 1543001..1544056 Escherichia coli O157:H7 str. EC4115 6967183 YP_002270041.1 CDS ECH74115_1584 NC_011353.1 1544069 1544404 D identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1544069..1544404 Escherichia coli O157:H7 str. EC4115 6967819 YP_002270042.1 CDS ECH74115_1585 NC_011353.1 1544417 1544830 D hypothetical protein 1544417..1544830 Escherichia coli O157:H7 str. EC4115 6971542 YP_002270043.1 CDS ECH74115_1587 NC_011353.1 1545051 1545578 D identified by match to protein family HMM PF07471; gp1 1545051..1545578 Escherichia coli O157:H7 str. EC4115 6966825 YP_002270044.1 CDS ECH74115_1586 NC_011353.1 1545558 1545782 R hypothetical protein complement(1545558..1545782) Escherichia coli O157:H7 str. EC4115 6971344 YP_002270045.1 CDS ECH74115_1588 NC_011353.1 1545834 1546115 D bacteriophage protein 1545834..1546115 Escherichia coli O157:H7 str. EC4115 6970314 YP_002270046.1 CDS phoQ NC_011353.1 1546716 1548176 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918; sensor protein PhoQ complement(1546716..1548176) Escherichia coli O157:H7 str. EC4115 6970070 YP_002270047.1 CDS phoP NC_011353.1 1548176 1548847 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1548176..1548847) Escherichia coli O157:H7 str. EC4115 6968523 YP_002270048.1 CDS purB NC_011353.1 1549016 1550386 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1549016..1550386) Escherichia coli O157:H7 str. EC4115 6966662 YP_002270049.1 CDS ECH74115_1593 NC_011353.1 1550390 1551031 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1550390..1551031) Escherichia coli O157:H7 str. EC4115 6970313 YP_002270050.1 CDS mnmA NC_011353.1 1551067 1552173 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1551067..1552173) Escherichia coli O157:H7 str. EC4115 6969671 YP_002270051.1 CDS ECH74115_1595 NC_011353.1 1552227 1552688 R identified by match to protein family HMM PF00293; NUDIX family hydrolase complement(1552227..1552688) Escherichia coli O157:H7 str. EC4115 6968345 YP_002270052.1 CDS rluE NC_011353.1 1552698 1553321 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1552698..1553321) Escherichia coli O157:H7 str. EC4115 6970712 YP_002270053.1 CDS ECH74115_1597 NC_011353.1 1553439 1553552 R hypothetical protein complement(1553439..1553552) Escherichia coli O157:H7 str. EC4115 6967179 YP_002270054.1 CDS icd NC_011353.1 1553523 1554773 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1553523..1554773 Escherichia coli O157:H7 str. EC4115 6968702 YP_002270055.1 CDS ECH74115_1599 NC_011353.1 1554887 1556029 R identified by match to protein family HMM PF00589; match to protein family HMM PF09003; intergrase complement(1554887..1556029) Escherichia coli O157:H7 str. EC4115 6970906 YP_002270056.1 CDS ECH74115_1600 NC_011353.1 1556359 1557183 D identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; replication protein O 1556359..1557183 Escherichia coli O157:H7 str. EC4115 6967432 YP_002270057.1 CDS ECH74115_1601 NC_011353.1 1557180 1557881 D identified by match to protein family HMM PF06992; replication protein P 1557180..1557881 Escherichia coli O157:H7 str. EC4115 6969753 YP_002270058.1 CDS ECH74115_1602 NC_011353.1 1557878 1558180 D hypothetical protein 1557878..1558180 Escherichia coli O157:H7 str. EC4115 6971090 YP_002270059.1 CDS emrE NC_011353.1 1558248 1558580 D member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 1558248..1558580 Escherichia coli O157:H7 str. EC4115 6967561 YP_002270060.1 CDS ECH74115_1606 NC_011353.1 1560849 1561304 D DLP12 prophage; hypothetical protein 1560849..1561304 Escherichia coli O157:H7 str. EC4115 6972020 YP_002270061.1 CDS ECH74115_1607 NC_011353.1 1561304 1561474 D DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 1561304..1561474 Escherichia coli O157:H7 str. EC4115 6968696 YP_002270062.1 CDS ECH74115_1608 NC_011353.1 1561467 1561757 D identified by match to protein family HMM PF07102; hypothetical protein 1561467..1561757 Escherichia coli O157:H7 str. EC4115 6970047 YP_002270063.1 CDS rusA NC_011353.1 1561754 1562116 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1561754..1562116 Escherichia coli O157:H7 str. EC4115 6967430 YP_002270064.1 CDS ECH74115_1610 NC_011353.1 1562116 1562253 D hypothetical protein 1562116..1562253 Escherichia coli O157:H7 str. EC4115 6968209 YP_002270065.1 CDS ECH74115_1611 NC_011353.1 1562250 1562939 D identified by match to protein family HMM PF06323; antitermination protein 1562250..1562939 Escherichia coli O157:H7 str. EC4115 6966804 YP_002270066.1 CDS ECH74115_1612 NC_011353.1 1563249 1563566 D gp13 1563249..1563566 Escherichia coli O157:H7 str. EC4115 6967569 YP_002270067.1 CDS ECH74115_1613 NC_011353.1 1563553 1564029 D identified by match to protein family HMM PF00959; lysozyme 1563553..1564029 Escherichia coli O157:H7 str. EC4115 6970608 YP_002270068.1 CDS ECH74115_1614 NC_011353.1 1564026 1564487 D identified by match to protein family HMM PF03245; bacteriophage lysis protein 1564026..1564487 Escherichia coli O157:H7 str. EC4115 6968330 YP_002270069.1 CDS ECH74115_1615 NC_011353.1 1564519 1564812 R identified by match to protein family HMM PF06291; Bor complement(1564519..1564812) Escherichia coli O157:H7 str. EC4115 6971565 YP_002270070.1 CDS ECH74115_1616 NC_011353.1 1565104 1565514 R identified by match to protein family HMM PF07166; hypothetical protein complement(1565104..1565514) Escherichia coli O157:H7 str. EC4115 6969955 YP_002270071.1 CDS ECH74115_1617 NC_011353.1 1565800 1566006 D hypothetical protein 1565800..1566006 Escherichia coli O157:H7 str. EC4115 6969375 YP_002270072.1 CDS ECH74115_1618 NC_011353.1 1566171 1566305 R hypothetical protein complement(1566171..1566305) Escherichia coli O157:H7 str. EC4115 6966616 YP_002270073.1 CDS ECH74115_1619 NC_011353.1 1566754 1567299 D identified by match to protein family HMM PF07471; phage DNA packaging protein Nu1 1566754..1567299 Escherichia coli O157:H7 str. EC4115 6970137 YP_002270074.1 CDS ECH74115_1620 NC_011353.1 1567274 1569199 D identified by match to protein family HMM PF05876; phage terminase large subunit 1567274..1569199 Escherichia coli O157:H7 str. EC4115 6968568 YP_002270075.1 CDS ECH74115_1621 NC_011353.1 1569196 1569402 D identified by match to protein family HMM PF02831; gpW 1569196..1569402 Escherichia coli O157:H7 str. EC4115 6969495 YP_002270076.1 CDS ECH74115_1622 NC_011353.1 1569399 1571000 D identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1569399..1571000 Escherichia coli O157:H7 str. EC4115 6970146 YP_002270077.1 CDS ECH74115_1623 NC_011353.1 1570981 1572300 D identified by match to protein family HMM PF01343; minor capsid protein C 1570981..1572300 Escherichia coli O157:H7 str. EC4115 6969781 YP_002270078.1 CDS ECH74115_1624 NC_011353.1 1572310 1572642 D identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1572310..1572642 Escherichia coli O157:H7 str. EC4115 6969153 YP_002270079.1 CDS ECH74115_1625 NC_011353.1 1572698 1573723 D identified by match to protein family HMM PF03864; phage major capsid protein E 1572698..1573723 Escherichia coli O157:H7 str. EC4115 6968519 YP_002270080.1 CDS ECH74115_1626 NC_011353.1 1573765 1574163 D DNA packaging protein FI 1573765..1574163 Escherichia coli O157:H7 str. EC4115 6967878 YP_002270081.1 CDS ECH74115_1627 NC_011353.1 1574175 1574528 D identified by match to protein family HMM PF05354; phage Head-Tail Attachment 1574175..1574528 Escherichia coli O157:H7 str. EC4115 6971578 YP_002270082.1 CDS ECH74115_1628 NC_011353.1 1574540 1575118 D identified by match to protein family HMM PF06763; prophage minor tail protein Z 1574540..1575118 Escherichia coli O157:H7 str. EC4115 6970947 YP_002270083.1 CDS ECH74115_1629 NC_011353.1 1575115 1575510 D identified by match to protein family HMM PF06141; phage minor tail protein U 1575115..1575510 Escherichia coli O157:H7 str. EC4115 6971258 YP_002270084.1 CDS ECH74115_1630 NC_011353.1 1575518 1576258 D identified by match to protein family HMM PF02368; major tail protein V 1575518..1576258 Escherichia coli O157:H7 str. EC4115 6969676 YP_002270085.1 CDS ECH74115_1631 NC_011353.1 1576274 1576696 D identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 1576274..1576696 Escherichia coli O157:H7 str. EC4115 6969010 YP_002270086.1 CDS ECH74115_1632 NC_011353.1 1576678 1577112 D identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 1576678..1577112 Escherichia coli O157:H7 str. EC4115 6968220 YP_002270087.1 CDS ECH74115_1633 NC_011353.1 1577105 1579654 D identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1577105..1579654 Escherichia coli O157:H7 str. EC4115 6969925 YP_002270088.1 CDS ECH74115_1634 NC_011353.1 1579651 1579980 D identified by match to protein family HMM PF05939; phage minor tail protein 1579651..1579980 Escherichia coli O157:H7 str. EC4115 6972240 YP_002270089.1 CDS ECH74115_1635 NC_011353.1 1579980 1580678 D identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1579980..1580678 Escherichia coli O157:H7 str. EC4115 6967294 YP_002270090.1 CDS ECH74115_1636 NC_011353.1 1580684 1581427 D identified by match to protein family HMM PF00877; tail assembly protein 1580684..1581427 Escherichia coli O157:H7 str. EC4115 6966677 YP_002270091.1 CDS ECH74115_1637 NC_011353.1 1581424 1581996 D identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1581424..1581996 Escherichia coli O157:H7 str. EC4115 6968707 YP_002270092.1 CDS ECH74115_1638 NC_011353.1 1582057 1585455 D identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 1582057..1585455 Escherichia coli O157:H7 str. EC4115 6969319 YP_002270093.1 CDS ECH74115_1639 NC_011353.1 1585522 1586121 D identified by match to protein family HMM PF06316; Ail/Lom family protein 1585522..1586121 Escherichia coli O157:H7 str. EC4115 6968514 YP_002270094.1 CDS ECH74115_1640 NC_011353.1 1586122 1586295 R hypothetical protein complement(1586122..1586295) Escherichia coli O157:H7 str. EC4115 6970598 YP_002270095.1 CDS ECH74115_1641 NC_011353.1 1586683 1587420 R hypothetical protein complement(1586683..1587420) Escherichia coli O157:H7 str. EC4115 6971939 YP_002270096.1 CDS ECH74115_1642 NC_011353.1 1587456 1587590 D identified by glimmer; hypothetical protein 1587456..1587590 Escherichia coli O157:H7 str. EC4115 6971351 YP_002270097.1 CDS ECH74115_1643 NC_011353.1 1587551 1589101 D identified by match to protein family HMM PF03335; match to protein family HMM PF03406; match to protein family HMM PF07484; prophage tail fiber domain-containing protein 1587551..1589101 Escherichia coli O157:H7 str. EC4115 6970828 YP_002270098.1 CDS ECH74115_1644 NC_011353.1 1589101 1589682 D identified by match to protein family HMM PF02413; tail fiber assembly protein 1589101..1589682 Escherichia coli O157:H7 str. EC4115 6971644 YP_002270099.1 CDS ECH74115_1645 NC_011353.1 1589802 1590692 R identified by match to protein family HMM PF05067; catalase complement(1589802..1590692) Escherichia coli O157:H7 str. EC4115 6969578 YP_002270100.1 CDS ECH74115_1646 NC_011353.1 1590711 1591217 R identified by match to protein family HMM PF05974; protein YciE complement(1590711..1591217) Escherichia coli O157:H7 str. EC4115 6970388 YP_002270101.1 CDS ECH74115_1647 NC_011353.1 1591254 1591754 R identified by match to protein family HMM PF05974; YciF protein complement(1591254..1591754) Escherichia coli O157:H7 str. EC4115 6969920 YP_002270102.1 CDS ECH74115_1648 NC_011353.1 1591833 1592015 R hypothetical protein complement(1591833..1592015) Escherichia coli O157:H7 str. EC4115 6970771 YP_002270103.1 CDS ECH74115_1649 NC_011353.1 1593238 1593486 D hypothetical protein 1593238..1593486 Escherichia coli O157:H7 str. EC4115 6971234 YP_002270104.1 CDS ECH74115_1650 NC_011353.1 1593939 1594286 D identified by match to protein family HMM PF05717; IS66 family element, orf2 1593939..1594286 Escherichia coli O157:H7 str. EC4115 6972049 YP_002270105.1 CDS ECH74115_1651 NC_011353.1 1594336 1595874 D identified by match to protein family HMM PF03050; IS66 family element, transposase 1594336..1595874 Escherichia coli O157:H7 str. EC4115 6966802 YP_002270106.1 CDS ECH74115_1652 NC_011353.1 1596177 1597661 R identified by match to protein family HMM PF00561; match to protein family HMM PF08386; hypothetical protein complement(1596177..1597661) Escherichia coli O157:H7 str. EC4115 6967251 YP_002270107.1 CDS ECH74115_1653 NC_011353.1 1597848 1598801 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(1597848..1598801) Escherichia coli O157:H7 str. EC4115 6971205 YP_002270108.1 CDS ECH74115_1654 NC_011353.1 1598936 1599064 D identified by glimmer; hypothetical protein 1598936..1599064 Escherichia coli O157:H7 str. EC4115 6972018 YP_002270109.1 CDS ECH74115_1655 NC_011353.1 1599300 1599884 D identified by match to protein family HMM PF01381; helix-turn-helix domain-containing protein 1599300..1599884 Escherichia coli O157:H7 str. EC4115 6966928 YP_002270110.1 CDS ECH74115_1656 NC_011353.1 1600058 1600384 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 1600058..1600384 Escherichia coli O157:H7 str. EC4115 6967544 YP_002270111.1 CDS ECH74115_1657 NC_011353.1 1600381 1601271 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1600381..1601271 Escherichia coli O157:H7 str. EC4115 6968534 YP_002270112.1 CDS ECH74115_1658 NC_011353.1 1601355 1602065 D identified by glimmer; hypothetical protein 1601355..1602065 Escherichia coli O157:H7 str. EC4115 6969283 YP_002270113.1 CDS minE NC_011353.1 1602437 1602703 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1602437..1602703) Escherichia coli O157:H7 str. EC4115 6970182 YP_002270114.1 CDS minD NC_011353.1 1602707 1603519 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1602707..1603519) Escherichia coli O157:H7 str. EC4115 6970981 YP_002270115.1 CDS minC NC_011353.1 1603543 1604238 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1603543..1604238) Escherichia coli O157:H7 str. EC4115 6972026 YP_002270116.1 CDS ECH74115_1662 NC_011353.1 1604758 1605126 D identified by match to protein family HMM PF05666; fels-1 Prophage Protein 1604758..1605126 Escherichia coli O157:H7 str. EC4115 6966747 YP_002270117.1 CDS ECH74115_1663 NC_011353.1 1605229 1605630 R identified by match to protein family HMM PF04151; hypothetical protein complement(1605229..1605630) Escherichia coli O157:H7 str. EC4115 6972091 YP_002270118.1 CDS ECH74115_1664 NC_011353.1 1605701 1605859 D hypothetical protein 1605701..1605859 Escherichia coli O157:H7 str. EC4115 6968915 YP_002270119.1 CDS ECH74115_1665 NC_011353.1 1605838 1606164 D hypothetical protein 1605838..1606164 Escherichia coli O157:H7 str. EC4115 6968289 YP_002270120.1 CDS ECH74115_1666 NC_011353.1 1606236 1606895 D identified by match to protein family HMM PF01557; hypothetical protein 1606236..1606895 Escherichia coli O157:H7 str. EC4115 6968759 YP_002270121.1 CDS ECH74115_1667 NC_011353.1 1606957 1607433 D identified by match to protein family HMM PF03692; hypothetical protein 1606957..1607433 Escherichia coli O157:H7 str. EC4115 6967940 YP_002270122.1 CDS hlyE NC_011353.1 1607640 1608695 R Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E complement(1607640..1608695) Escherichia coli O157:H7 str. EC4115 6970737 YP_002270123.1 CDS umuD NC_011353.1 1608924 1609343 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1608924..1609343 Escherichia coli O157:H7 str. EC4115 6972318 YP_002270124.1 CDS umuC NC_011353.1 1609343 1610611 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1609343..1610611 Escherichia coli O157:H7 str. EC4115 6972022 YP_002270125.1 CDS dsbB NC_011353.1 1610657 1611193 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1610657..1611193) Escherichia coli O157:H7 str. EC4115 6971769 YP_002270126.1 CDS nhaB NC_011353.1 1611333 1612874 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1611333..1612874) Escherichia coli O157:H7 str. EC4115 6968270 YP_002270127.1 CDS fadR NC_011353.1 1613096 1613815 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1613096..1613815 Escherichia coli O157:H7 str. EC4115 6971617 YP_002270128.1 CDS ECH74115_1675 NC_011353.1 1613867 1615399 R identified by match to protein family HMM PF04293; SpoVR family protein complement(1613867..1615399) Escherichia coli O157:H7 str. EC4115 6966897 YP_002270129.1 CDS dadA NC_011353.1 1615756 1617060 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1615756..1617060 Escherichia coli O157:H7 str. EC4115 6967855 YP_002270130.1 CDS dadX NC_011353.1 1617070 1618140 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1617070..1618140 Escherichia coli O157:H7 str. EC4115 6966615 YP_002270131.1 CDS ECH74115_1678 NC_011353.1 1618529 1620265 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1618529..1620265) Escherichia coli O157:H7 str. EC4115 6967354 YP_002270132.1 CDS ldcA NC_011353.1 1620361 1621275 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1620361..1621275) Escherichia coli O157:H7 str. EC4115 6968175 YP_002270133.1 CDS mltE NC_011353.1 1621375 1621986 D identified by match to protein family HMM PF01464; membrane-bound lytic murein transglycosylase E 1621375..1621986 Escherichia coli O157:H7 str. EC4115 6968761 YP_002270134.1 CDS ECH74115_1681 NC_011353.1 1621988 1622143 R YcgR family protein complement(1621988..1622143) Escherichia coli O157:H7 str. EC4115 6971957 YP_002270135.1 CDS ECH74115_1682 NC_011353.1 1622095 1623255 R hypothetical protein complement(1622095..1623255) Escherichia coli O157:H7 str. EC4115 6970051 YP_002270136.1 CDS ECH74115_1683 NC_011353.1 1623600 1623803 D identified by glimmer; hypothetical protein 1623600..1623803 Escherichia coli O157:H7 str. EC4115 6967512 YP_002270137.1 CDS engD NC_011353.1 1624099 1625190 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1624099..1625190) Escherichia coli O157:H7 str. EC4115 6970747 YP_002270138.1 CDS pth NC_011353.1 1625307 1625891 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1625307..1625891) Escherichia coli O157:H7 str. EC4115 6969922 YP_002270139.1 CDS ECH74115_1686 NC_011353.1 1626169 1626447 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1626169..1626447 Escherichia coli O157:H7 str. EC4115 6969634 YP_002270140.1 CDS ychM NC_011353.1 1626502 1628181 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1626502..1628181) Escherichia coli O157:H7 str. EC4115 6970448 YP_002270141.1 CDS prs NC_011353.1 1628306 1629253 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1628306..1629253) Escherichia coli O157:H7 str. EC4115 6968392 YP_002270142.1 CDS ipk NC_011353.1 1629404 1630255 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1629404..1630255) Escherichia coli O157:H7 str. EC4115 6969234 YP_002270143.1 CDS lolB NC_011353.1 1630255 1630878 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1630255..1630878) Escherichia coli O157:H7 str. EC4115 6967212 YP_002270144.1 CDS hemA NC_011353.1 1631092 1632348 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1631092..1632348 Escherichia coli O157:H7 str. EC4115 6967831 YP_002270145.1 CDS prfA NC_011353.1 1632390 1633472 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1632390..1633472 Escherichia coli O157:H7 str. EC4115 6971675 YP_002270146.1 CDS hemK NC_011353.1 1633472 1634305 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1633472..1634305 Escherichia coli O157:H7 str. EC4115 6969450 YP_002270147.1 CDS ECH74115_1694 NC_011353.1 1634302 1634694 D identified by match to protein family HMM PF04247; transcriptional regulator 1634302..1634694 Escherichia coli O157:H7 str. EC4115 6967006 YP_002270148.1 CDS sirB1 NC_011353.1 1634698 1635507 D transcriptional regulator 1634698..1635507 Escherichia coli O157:H7 str. EC4115 6969240 YP_002270149.1 CDS kdsA NC_011353.1 1635543 1636397 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1635543..1636397 Escherichia coli O157:H7 str. EC4115 6968634 YP_002270150.1 CDS ECH74115_1699 NC_011353.1 1637587 1638687 R identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846; calcium/sodium:proton antiporter complement(1637587..1638687) Escherichia coli O157:H7 str. EC4115 6968751 YP_002270151.1 CDS chaB NC_011353.1 1638957 1639187 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1638957..1639187 Escherichia coli O157:H7 str. EC4115 6968626 YP_002270152.1 CDS ECH74115_1701 NC_011353.1 1639348 1640043 D identified by match to protein family HMM PF04752; chaC protein 1639348..1640043 Escherichia coli O157:H7 str. EC4115 6970658 YP_002270153.1 CDS ECH74115_1702 NC_011353.1 1640087 1640440 R identified by match to protein family HMM PF02635; dsrE family protein complement(1640087..1640440) Escherichia coli O157:H7 str. EC4115 6971768 YP_002270154.1 CDS ECH74115_1703 NC_011353.1 1640590 1642020 D hypothetical protein 1640590..1642020 Escherichia coli O157:H7 str. EC4115 6971148 YP_002270155.1 CDS narL NC_011353.1 1642021 1642671 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1642021..1642671) Escherichia coli O157:H7 str. EC4115 6968112 YP_002270156.1 CDS narX NC_011353.1 1642664 1644460 R identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarX complement(1642664..1644460) Escherichia coli O157:H7 str. EC4115 6967517 YP_002270157.1 CDS ECH74115_1706 NC_011353.1 1644486 1644704 D identified by glimmer; hypothetical protein 1644486..1644704 Escherichia coli O157:H7 str. EC4115 6966829 YP_002270158.1 CDS narK NC_011353.1 1644799 1646190 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 1 1644799..1646190 Escherichia coli O157:H7 str. EC4115 6972216 YP_002270159.1 CDS narG NC_011353.1 1646583 1650326 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase 1 subunit alpha 1646583..1650326 Escherichia coli O157:H7 str. EC4115 6971407 YP_002270160.1 CDS narH NC_011353.1 1650323 1651861 D identified by match to protein family HMM TIGR01660; nitrate reductase 1 subunit beta 1650323..1651861 Escherichia coli O157:H7 str. EC4115 6970473 YP_002270161.1 CDS narJ NC_011353.1 1651858 1652568 D identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 1 1651858..1652568 Escherichia coli O157:H7 str. EC4115 6969688 YP_002270162.1 CDS narI NC_011353.1 1652568 1653245 D identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase 1 subunit gamma 1652568..1653245 Escherichia coli O157:H7 str. EC4115 6968901 YP_002270163.1 CDS purU NC_011353.1 1654323 1655165 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1654323..1655165) Escherichia coli O157:H7 str. EC4115 6972428 YP_002270164.1 CDS ECH74115_1718 NC_011353.1 1655215 1655694 R identified by match to protein family HMM PF02810; hypothetical protein complement(1655215..1655694) Escherichia coli O157:H7 str. EC4115 6967155 YP_002270165.1 CDS ECH74115_1719 NC_011353.1 1655747 1656691 D identified by match to protein family HMM PF01734; hypothetical protein 1655747..1656691 Escherichia coli O157:H7 str. EC4115 6968391 YP_002270166.1 CDS ECH74115_1720 NC_011353.1 1656783 1657796 D identified by match to protein family HMM PF00072; response regulator of RpoS 1656783..1657796 Escherichia coli O157:H7 str. EC4115 6969065 YP_002270167.1 CDS galU NC_011353.1 1657998 1658906 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1657998..1658906 Escherichia coli O157:H7 str. EC4115 6967088 YP_002270168.1 CDS hns NC_011353.1 1659050 1659463 R identified by match to protein family HMM PF00816; global DNA-binding transcriptional dual regulator H-NS complement(1659050..1659463) Escherichia coli O157:H7 str. EC4115 6967890 YP_002270169.1 CDS ECH74115_1723 NC_011353.1 1659555 1659683 R identified by glimmer; hypothetical protein complement(1659555..1659683) Escherichia coli O157:H7 str. EC4115 6970835 YP_002270170.1 CDS tdk NC_011353.1 1660067 1660684 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1660067..1660684 Escherichia coli O157:H7 str. EC4115 6971790 YP_002270171.1 CDS adhE NC_011353.1 1660985 1663660 R identified by match to protein family HMM PF00171; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1660985..1663660) Escherichia coli O157:H7 str. EC4115 6969701 YP_002270172.1 CDS ECH74115_1726 NC_011353.1 1664137 1664784 D identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1664137..1664784 Escherichia coli O157:H7 str. EC4115 6968331 YP_002270173.1 CDS ECH74115_1728 NC_011353.1 1664811 1664966 D identified by glimmer; hypothetical protein 1664811..1664966 Escherichia coli O157:H7 str. EC4115 6969149 YP_002270174.1 CDS oppA NC_011353.1 1665477 1667153 D identified by match to protein family HMM PF00496; oligopeptide ABC transporter substrate-binding protein 1665477..1667153 Escherichia coli O157:H7 str. EC4115 6967073 YP_002270175.1 CDS oppB NC_011353.1 1667239 1668159 D identified by match to protein family HMM PF00528; oligopeptide transporter permease 1667239..1668159 Escherichia coli O157:H7 str. EC4115 6971213 YP_002270176.1 CDS oppC NC_011353.1 1668177 1669082 D identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease OppC 1668177..1669082 Escherichia coli O157:H7 str. EC4115 6969603 YP_002270177.1 CDS oppD NC_011353.1 1669094 1670107 D identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1669094..1670107 Escherichia coli O157:H7 str. EC4115 6970793 YP_002270178.1 CDS oppF NC_011353.1 1670104 1671108 D identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein OppF 1670104..1671108 Escherichia coli O157:H7 str. EC4115 6968405 YP_002270179.1 CDS ECH74115_1734 NC_011353.1 1671161 1671490 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1671161..1671490) Escherichia coli O157:H7 str. EC4115 6968848 YP_002270180.1 CDS cls NC_011353.1 1671525 1672985 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1671525..1672985) Escherichia coli O157:H7 str. EC4115 6967126 YP_002270181.1 CDS ECH74115_1736 NC_011353.1 1673149 1673301 D hypothetical protein 1673149..1673301 Escherichia coli O157:H7 str. EC4115 6970889 YP_002270182.1 CDS kch NC_011353.1 1673356 1674564 R identified by match to protein family HMM PF02254; match to protein family HMM PF07885; voltage-gated potassium channel complement(1673356..1674564) Escherichia coli O157:H7 str. EC4115 6971668 YP_002270183.1 CDS ECH74115_1738 NC_011353.1 1674910 1675206 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1674910..1675206) Escherichia coli O157:H7 str. EC4115 6969630 YP_002270184.1 CDS tonB NC_011353.1 1675430 1676149 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1675430..1676149 Escherichia coli O157:H7 str. EC4115 6967035 YP_002270185.1 CDS yciA NC_011353.1 1676189 1676587 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1676189..1676587) Escherichia coli O157:H7 str. EC4115 6967411 YP_002270186.1 CDS ispZ NC_011353.1 1676692 1677231 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1676692..1677231) Escherichia coli O157:H7 str. EC4115 6971406 YP_002270187.1 CDS ompW NC_011353.1 1678361 1678999 D receptor for colicin S4; outer membrane protein W 1678361..1678999 Escherichia coli O157:H7 str. EC4115 6969443 YP_002270188.1 CDS ECH74115_1744 NC_011353.1 1679045 1680175 R identified by match to protein family HMM PF00589; match to protein family HMM PF09003; site-specific recombinase, phage integrase family complement(1679045..1680175) Escherichia coli O157:H7 str. EC4115 6968303 YP_002270189.1 CDS ECH74115_1745 NC_011353.1 1680466 1682937 R identified by match to protein family HMM PF00929; exonuclease family protein complement(1680466..1682937) Escherichia coli O157:H7 str. EC4115 6969126 YP_002270190.1 CDS ECH74115_1746 NC_011353.1 1683030 1683221 R identified by match to protein family HMM PF07358; hypothetical protein complement(1683030..1683221) Escherichia coli O157:H7 str. EC4115 6967097 YP_002270191.1 CDS ECH74115_1747 NC_011353.1 1683218 1683406 R identified by match to protein family HMM PF05358; DicB protein complement(1683218..1683406) Escherichia coli O157:H7 str. EC4115 6967885 YP_002270192.1 CDS ECH74115_1748 NC_011353.1 1683423 1683545 D identified by glimmer; hypothetical protein 1683423..1683545 Escherichia coli O157:H7 str. EC4115 6970890 YP_002270193.1 CDS ECH74115_1750 NC_011353.1 1683965 1684198 D hypothetical protein 1683965..1684198 Escherichia coli O157:H7 str. EC4115 6971843 YP_002270194.1 CDS ECH74115_1749 NC_011353.1 1684176 1684583 R hypothetical protein complement(1684176..1684583) Escherichia coli O157:H7 str. EC4115 6967016 YP_002270195.1 CDS ECH74115_1751 NC_011353.1 1684606 1684824 R identified by glimmer; hypothetical protein complement(1684606..1684824) Escherichia coli O157:H7 str. EC4115 6969056 YP_002270196.1 CDS ECH74115_1752 NC_011353.1 1684897 1685196 R hypothetical protein complement(1684897..1685196) Escherichia coli O157:H7 str. EC4115 6969423 YP_002270197.1 CDS ECH74115_1753 NC_011353.1 1685586 1685720 D identified by glimmer; hypothetical protein 1685586..1685720 Escherichia coli O157:H7 str. EC4115 6970223 YP_002270198.1 CDS ECH74115_1754 NC_011353.1 1685944 1686171 D DNA-binding transcriptional regulator DicC 1685944..1686171 Escherichia coli O157:H7 str. EC4115 6971086 YP_002270199.1 CDS ECH74115_1756 NC_011353.1 1686677 1687717 D hypothetical protein 1686677..1687717 Escherichia coli O157:H7 str. EC4115 6967541 YP_002270200.1 CDS ECH74115_1757 NC_011353.1 1687749 1688171 D hypothetical protein 1687749..1688171 Escherichia coli O157:H7 str. EC4115 6967631 YP_002270201.1 CDS ECH74115_1759 NC_011353.1 1688975 1689100 D hypothetical protein 1688975..1689100 Escherichia coli O157:H7 str. EC4115 6969695 YP_002270202.1 CDS ECH74115_1760 NC_011353.1 1689811 1690557 D porcine attaching-effacing associated protein 1689811..1690557 Escherichia coli O157:H7 str. EC4115 6971579 YP_002270203.1 CDS ECH74115_1761 NC_011353.1 1691269 1691526 D hypothetical protein 1691269..1691526 Escherichia coli O157:H7 str. EC4115 6970936 YP_002270204.1 CDS ECH74115_1762 NC_011353.1 1691543 1691674 R identified by glimmer; hypothetical protein complement(1691543..1691674) Escherichia coli O157:H7 str. EC4115 6966698 YP_002270205.1 CDS ECH74115_1763 NC_011353.1 1691876 1692922 D identified by match to protein family HMM PF06914; hypothetical protein 1691876..1692922 Escherichia coli O157:H7 str. EC4115 6969255 YP_002270206.1 CDS ECH74115_1764 NC_011353.1 1692935 1693294 D identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1692935..1693294 Escherichia coli O157:H7 str. EC4115 6968643 YP_002270207.1 CDS ECH74115_1765 NC_011353.1 1693303 1693833 D identified by match to protein family HMM PF06576; hypothetical protein 1693303..1693833 Escherichia coli O157:H7 str. EC4115 6970537 YP_002270208.1 CDS ECH74115_1766 NC_011353.1 1694075 1694272 D hypothetical protein 1694075..1694272 Escherichia coli O157:H7 str. EC4115 6971960 YP_002270209.1 CDS ECH74115_1767 NC_011353.1 1694423 1695481 D identified by match to protein family HMM PF01555; DNA methylase 1694423..1695481 Escherichia coli O157:H7 str. EC4115 6971334 YP_002270210.1 CDS ECH74115_1772 NC_011353.1 1697248 1697463 D identified by match to protein family HMM PF04971; hypothetical protein 1697248..1697463 Escherichia coli O157:H7 str. EC4115 6968234 YP_002270211.1 CDS ECH74115_1773 NC_011353.1 1697468 1697812 D identified by match to protein family HMM PF07041; hypothetical protein 1697468..1697812 Escherichia coli O157:H7 str. EC4115 6966551 YP_002270212.1 CDS ECH74115_1774 NC_011353.1 1697863 1698396 D identified by match to protein family HMM PF00959; phage lysozyme 1697863..1698396 Escherichia coli O157:H7 str. EC4115 6967828 YP_002270213.1 CDS ECH74115_1775 NC_011353.1 1698667 1699236 D anti-repressor protein Ant 1698667..1699236 Escherichia coli O157:H7 str. EC4115 6971362 YP_002270214.1 CDS ECH74115_1776 NC_011353.1 1699236 1699382 D hypothetical protein 1699236..1699382 Escherichia coli O157:H7 str. EC4115 6971982 YP_002270215.1 CDS ECH74115_1777 NC_011353.1 1699390 1699857 D identified by match to protein family HMM PF03245; bacteriophage lysis protein 1699390..1699857 Escherichia coli O157:H7 str. EC4115 6969776 YP_002270216.1 CDS ECH74115_1778 NC_011353.1 1699940 1700080 D hypothetical protein 1699940..1700080 Escherichia coli O157:H7 str. EC4115 6969677 YP_002270217.1 CDS ECH74115_1779 NC_011353.1 1700106 1700273 D identified by glimmer; hypothetical protein 1700106..1700273 Escherichia coli O157:H7 str. EC4115 6968797 YP_002270218.1 CDS ECH74115_1780 NC_011353.1 1700717 1700881 R hypothetical protein complement(1700717..1700881) Escherichia coli O157:H7 str. EC4115 6966733 YP_002270219.1 CDS ECH74115_1782 NC_011353.1 1701328 1701873 D identified by match to protein family HMM PF07471; terminase small subunit 1701328..1701873 Escherichia coli O157:H7 str. EC4115 6972100 YP_002270220.1 CDS ECH74115_1783 NC_011353.1 1701848 1703773 D identified by match to protein family HMM PF05876; phage terminase large subunit 1701848..1703773 Escherichia coli O157:H7 str. EC4115 6968357 YP_002270221.1 CDS ECH74115_1784 NC_011353.1 1703770 1703976 D identified by match to protein family HMM PF02831; gpW 1703770..1703976 Escherichia coli O157:H7 str. EC4115 6968871 YP_002270222.1 CDS ECH74115_1785 NC_011353.1 1703973 1705574 D identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1703973..1705574 Escherichia coli O157:H7 str. EC4115 6969667 YP_002270223.1 CDS ECH74115_1786 NC_011353.1 1705555 1706874 D identified by match to protein family HMM PF01343; minor capsid protein C 1705555..1706874 Escherichia coli O157:H7 str. EC4115 6970142 YP_002270224.1 CDS ECH74115_1787 NC_011353.1 1706884 1707216 D identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1706884..1707216 Escherichia coli O157:H7 str. EC4115 6970956 YP_002270225.1 CDS ECH74115_1788 NC_011353.1 1707272 1708297 D identified by match to protein family HMM PF03864; phage major capsid protein E 1707272..1708297 Escherichia coli O157:H7 str. EC4115 6971438 YP_002270226.1 CDS ECH74115_1789 NC_011353.1 1708339 1708737 D DNA packaging protein FI 1708339..1708737 Escherichia coli O157:H7 str. EC4115 6972175 YP_002270227.1 CDS ECH74115_1790 NC_011353.1 1708749 1709102 D identified by match to protein family HMM PF05354; phage Head-Tail Attachment 1708749..1709102 Escherichia coli O157:H7 str. EC4115 6968591 YP_002270228.1 CDS ECH74115_1791 NC_011353.1 1709117 1709650 D identified by match to protein family HMM PF06763; prophage minor tail protein Z 1709117..1709650 Escherichia coli O157:H7 str. EC4115 6967547 YP_002270229.1 CDS ECH74115_1792 NC_011353.1 1709647 1710042 D identified by match to protein family HMM PF06141; phage minor tail protein U 1709647..1710042 Escherichia coli O157:H7 str. EC4115 6967967 YP_002270230.1 CDS ECH74115_1793 NC_011353.1 1710050 1710802 D identified by match to protein family HMM PF02368; major tail protein V 1710050..1710802 Escherichia coli O157:H7 str. EC4115 6969744 YP_002270231.1 CDS ECH74115_1795 NC_011353.1 1711265 1711573 D identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 1711265..1711573 Escherichia coli O157:H7 str. EC4115 6971386 YP_002270232.1 CDS ECH74115_1796 NC_011353.1 1711617 1714262 D identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1711617..1714262 Escherichia coli O157:H7 str. EC4115 6972210 YP_002270233.1 CDS ECH74115_1797 NC_011353.1 1714259 1714588 D identified by match to protein family HMM PF05939; phage minor tail protein 1714259..1714588 Escherichia coli O157:H7 str. EC4115 6966687 YP_002270234.1 CDS ECH74115_1798 NC_011353.1 1714588 1715286 D identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1714588..1715286 Escherichia coli O157:H7 str. EC4115 6967302 YP_002270235.1 CDS ECH74115_1800 NC_011353.1 1716037 1716615 D identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1716037..1716615 Escherichia coli O157:H7 str. EC4115 6968990 YP_002270236.1 CDS ECH74115_1801 NC_011353.1 1716661 1716780 D identified by glimmer; hypothetical protein 1716661..1716780 Escherichia coli O157:H7 str. EC4115 6972065 YP_002270237.1 CDS ECH74115_1802 NC_011353.1 1716856 1719711 D identified by match to protein family HMM PF09327; hypothetical protein 1716856..1719711 Escherichia coli O157:H7 str. EC4115 6971212 YP_002270238.1 CDS ECH74115_1803 NC_011353.1 1719779 1720378 D identified by match to protein family HMM PF06316; Ail/Lom family protein 1719779..1720378 Escherichia coli O157:H7 str. EC4115 6966787 YP_002270239.1 CDS ECH74115_1804 NC_011353.1 1720530 1721834 D identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 1720530..1721834 Escherichia coli O157:H7 str. EC4115 6969034 YP_002270240.1 CDS ECH74115_1805 NC_011353.1 1721836 1722105 D identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 1721836..1722105 Escherichia coli O157:H7 str. EC4115 6968007 YP_002270241.1 CDS ECH74115_1806 NC_011353.1 1722776 1722922 R identified by glimmer; hypothetical protein complement(1722776..1722922) Escherichia coli O157:H7 str. EC4115 6970302 YP_002270242.1 CDS ECH74115_1807 NC_011353.1 1723132 1724457 R NleA11 protein complement(1723132..1724457) Escherichia coli O157:H7 str. EC4115 6971715 YP_002270243.1 CDS ECH74115_1809 NC_011353.1 1726284 1727195 D non-LEE-encoded effector NleH 1726284..1727195 Escherichia coli O157:H7 str. EC4115 6971446 YP_002270244.1 CDS ECH74115_1812 NC_011353.1 1728796 1730334 R identified by match to protein family HMM PF03050; IS66 family element, transposase complement(1728796..1730334) Escherichia coli O157:H7 str. EC4115 6969661 YP_002270245.1 CDS ECH74115_1813 NC_011353.1 1730384 1730731 R identified by match to protein family HMM PF05717; IS66 family element, orf2 complement(1730384..1730731) Escherichia coli O157:H7 str. EC4115 6971166 YP_002270246.1 CDS ECH74115_1814 NC_011353.1 1732437 1732967 R identified by match to protein family HMM PF06416; hypothetical protein complement(1732437..1732967) Escherichia coli O157:H7 str. EC4115 6967310 YP_002270247.1 CDS ECH74115_1815 NC_011353.1 1733268 1733858 D identified by match to protein family HMM PF03278; EspM3 protein 1733268..1733858 Escherichia coli O157:H7 str. EC4115 6966576 YP_002270248.1 CDS ECH74115_1820 NC_011353.1 1737154 1737270 D outer membrane protein W 1737154..1737270 Escherichia coli O157:H7 str. EC4115 6971268 YP_002270249.1 CDS ECH74115_1821 NC_011353.1 1737316 1738446 R identified by match to protein family HMM PF00589; match to protein family HMM PF09003; site-specific recombinase, phage integrase family complement(1737316..1738446) Escherichia coli O157:H7 str. EC4115 6969159 YP_002270250.1 CDS ECH74115_1822 NC_011353.1 1738865 1741180 R identified by match to protein family HMM PF06630; exonuclease family protein complement(1738865..1741180) Escherichia coli O157:H7 str. EC4115 6968323 YP_002270251.1 CDS ECH74115_1823 NC_011353.1 1741273 1741401 R identified by match to protein family HMM PF07358; hypothetical protein complement(1741273..1741401) Escherichia coli O157:H7 str. EC4115 6971716 YP_002270252.1 CDS ECH74115_1825 NC_011353.1 1742044 1742208 D hypothetical protein 1742044..1742208 Escherichia coli O157:H7 str. EC4115 6967269 YP_002270253.1 CDS ECH74115_1826 NC_011353.1 1742212 1742430 R identified by glimmer; hypothetical protein complement(1742212..1742430) Escherichia coli O157:H7 str. EC4115 6967092 YP_002270254.1 CDS ECH74115_1827 NC_011353.1 1742460 1742588 R identified by glimmer; hypothetical protein complement(1742460..1742588) Escherichia coli O157:H7 str. EC4115 6968540 YP_002270255.1 CDS ECH74115_1828 NC_011353.1 1742590 1742745 R identified by match to protein family HMM PF07151; hypothetical protein complement(1742590..1742745) Escherichia coli O157:H7 str. EC4115 6967622 YP_002270256.1 CDS ECH74115_1829 NC_011353.1 1742935 1743069 R HTH-type transcriptional regulator DicA complement(1742935..1743069) Escherichia coli O157:H7 str. EC4115 6970444 YP_002270257.1 CDS ECH74115_1830 NC_011353.1 1743108 1743314 D identified by glimmer; hypothetical protein 1743108..1743314 Escherichia coli O157:H7 str. EC4115 6969593 YP_002270258.1 CDS ECH74115_1831 NC_011353.1 1743420 1743647 D DNA-binding transcriptional regulator DicC 1743420..1743647 Escherichia coli O157:H7 str. EC4115 6971435 YP_002270259.1 CDS ECH74115_1832 NC_011353.1 1743691 1744182 D identified by match to protein family HMM PF06254; hypothetical protein 1743691..1744182 Escherichia coli O157:H7 str. EC4115 6971745 YP_002270260.1 CDS ECH74115_1833 NC_011353.1 1744154 1745194 D hypothetical protein 1744154..1745194 Escherichia coli O157:H7 str. EC4115 6971999 YP_002270261.1 CDS ECH74115_1834 NC_011353.1 1745226 1745648 D hypothetical protein 1745226..1745648 Escherichia coli O157:H7 str. EC4115 6969780 YP_002270262.1 CDS ECH74115_1835 NC_011353.1 1745683 1746453 D identified by match to protein family HMM PF07789; hypothetical protein 1745683..1746453 Escherichia coli O157:H7 str. EC4115 6967313 YP_002270263.1 CDS ECH74115_1836 NC_011353.1 1746469 1746864 D identified by match to protein family HMM PF06163; hypothetical protein 1746469..1746864 Escherichia coli O157:H7 str. EC4115 6971357 YP_002270264.1 CDS ECH74115_1837 NC_011353.1 1746921 1747277 D hypothetical protein 1746921..1747277 Escherichia coli O157:H7 str. EC4115 6966800 YP_002270265.1 CDS ECH74115_1838 NC_011353.1 1747326 1747538 D hypothetical protein 1747326..1747538 Escherichia coli O157:H7 str. EC4115 6967270 YP_002270266.1 CDS ECH74115_1839 NC_011353.1 1747574 1747945 D hypothetical protein 1747574..1747945 Escherichia coli O157:H7 str. EC4115 6970528 YP_002270267.1 CDS ECH74115_1840 NC_011353.1 1747942 1748304 D identified by match to protein family HMM PF04448; hypothetical protein 1747942..1748304 Escherichia coli O157:H7 str. EC4115 6968983 YP_002270268.1 CDS ECH74115_1841 NC_011353.1 1748375 1748524 D hypothetical protein 1748375..1748524 Escherichia coli O157:H7 str. EC4115 6971973 YP_002270269.1 CDS ECH74115_1842 NC_011353.1 1749146 1749403 D hypothetical protein 1749146..1749403 Escherichia coli O157:H7 str. EC4115 6967164 YP_002270270.1 CDS ECH74115_1844 NC_011353.1 1749753 1750802 D identified by match to protein family HMM PF06914; hypothetical protein 1749753..1750802 Escherichia coli O157:H7 str. EC4115 6966856 YP_002270271.1 CDS ECH74115_1845 NC_011353.1 1750815 1751189 D identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1750815..1751189 Escherichia coli O157:H7 str. EC4115 6970741 YP_002270272.1 CDS ECH74115_1846 NC_011353.1 1751186 1752007 D identified by match to protein family HMM PF03589; antitermination protein Q 1751186..1752007 Escherichia coli O157:H7 str. EC4115 6971385 YP_002270273.1 CDS ECH74115_1847 NC_011353.1 1752234 1752431 D hypothetical protein 1752234..1752431 Escherichia coli O157:H7 str. EC4115 6969125 YP_002270274.1 CDS ECH74115_1848 NC_011353.1 1752582 1753640 D identified by match to protein family HMM PF01555; DNA methylase 1752582..1753640 Escherichia coli O157:H7 str. EC4115 6970018 YP_002270275.1 CDS ECH74115_1849 NC_011353.1 1753687 1753806 R identified by glimmer; hypothetical protein complement(1753687..1753806) Escherichia coli O157:H7 str. EC4115 6972352 YP_002270276.1 CDS ECH74115_1851 NC_011353.1 1753848 1753994 R hypothetical protein complement(1753848..1753994) Escherichia coli O157:H7 str. EC4115 6968410 YP_002270277.1 CDS ECH74115_1852 NC_011353.1 1754235 1756181 D identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 1754235..1756181 Escherichia coli O157:H7 str. EC4115 6971286 YP_002270278.1 CDS ECH74115_1853 NC_011353.1 1756178 1756303 D hypothetical protein 1756178..1756303 Escherichia coli O157:H7 str. EC4115 6970363 YP_002270279.1 CDS ECH74115_1854 NC_011353.1 1756316 1756495 D identified by match to protein family HMM PF07125; hypothetical protein 1756316..1756495 Escherichia coli O157:H7 str. EC4115 6971069 YP_002270280.1 CDS ECH74115_1855 NC_011353.1 1756536 1756781 D identified by match to protein family HMM PF05696; hypothetical protein 1756536..1756781 Escherichia coli O157:H7 str. EC4115 6969886 YP_002270281.1 CDS ECH74115_1856 NC_011353.1 1756859 1757074 D identified by match to protein family HMM PF04971; hypothetical protein 1756859..1757074 Escherichia coli O157:H7 str. EC4115 6972206 YP_002270282.1 CDS ECH74115_1857 NC_011353.1 1757078 1757635 D hypothetical protein 1757078..1757635 Escherichia coli O157:H7 str. EC4115 6971372 YP_002270283.1 CDS ECH74115_1858 NC_011353.1 1757672 1758205 D identified by match to protein family HMM PF00959; lysozyme 1757672..1758205 Escherichia coli O157:H7 str. EC4115 6967337 YP_002270284.1 CDS ECH74115_1859 NC_011353.1 1758504 1758971 D identified by match to protein family HMM PF03245; bacteriophage lysis protein 1758504..1758971 Escherichia coli O157:H7 str. EC4115 6966554 YP_002270285.1 CDS ECH74115_1860 NC_011353.1 1759384 1759860 D identified by match to protein family HMM PF07278; bacteriophage terminase, small subunit 1759384..1759860 Escherichia coli O157:H7 str. EC4115 6968713 YP_002270286.1 CDS ECH74115_1861 NC_011353.1 1759857 1761980 D identified by match to protein family HMM PF05876; phage terminase large subunit 1759857..1761980 Escherichia coli O157:H7 str. EC4115 6968173 YP_002270287.1 CDS ECH74115_1862 NC_011353.1 1761977 1762189 D hypothetical protein 1761977..1762189 Escherichia coli O157:H7 str. EC4115 6969771 YP_002270288.1 CDS ECH74115_1863 NC_011353.1 1762189 1763691 D identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1762189..1763691 Escherichia coli O157:H7 str. EC4115 6972102 YP_002270289.1 CDS clpP NC_011353.1 1763705 1765660 D identified by match to protein family HMM PF00574; Clp protease domain-containing protein 1763705..1765660 Escherichia coli O157:H7 str. EC4115 6969826 YP_002270290.1 CDS ECH74115_1865 NC_011353.1 1765748 1766074 D membrane protein 1765748..1766074 Escherichia coli O157:H7 str. EC4115 6971147 YP_002270291.1 CDS ECH74115_1866 NC_011353.1 1766100 1766348 D hypothetical protein 1766100..1766348 Escherichia coli O157:H7 str. EC4115 6970380 YP_002270292.1 CDS ECH74115_1867 NC_011353.1 1766351 1766974 D identified by match to protein family HMM PF06763; prophage minor tail protein Z 1766351..1766974 Escherichia coli O157:H7 str. EC4115 6969412 YP_002270293.1 CDS ECH74115_1868 NC_011353.1 1766987 1767385 D identified by match to protein family HMM PF06141; phage minor tail protein U 1766987..1767385 Escherichia coli O157:H7 str. EC4115 6969343 YP_002270294.1 CDS ECH74115_1869 NC_011353.1 1767393 1768145 D identified by match to protein family HMM PF02368; major tail protein V 1767393..1768145 Escherichia coli O157:H7 str. EC4115 6968520 YP_002270295.1 CDS ECH74115_1870 NC_011353.1 1768159 1768581 D identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 1768159..1768581 Escherichia coli O157:H7 str. EC4115 6967737 YP_002270296.1 CDS ECH74115_1871 NC_011353.1 1768632 1768916 D identified by match to protein family HMM TIGR01715; phage tail assembly protein T 1768632..1768916 Escherichia coli O157:H7 str. EC4115 6966904 YP_002270297.1 CDS ECH74115_1872 NC_011353.1 1768960 1771605 D identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1768960..1771605 Escherichia coli O157:H7 str. EC4115 6967657 YP_002270298.1 CDS ECH74115_1873 NC_011353.1 1771602 1771931 D identified by match to protein family HMM PF05939; phage minor tail protein 1771602..1771931 Escherichia coli O157:H7 str. EC4115 6967040 YP_002270299.1 CDS ECH74115_1874 NC_011353.1 1771931 1772629 D identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1771931..1772629 Escherichia coli O157:H7 str. EC4115 6969057 YP_002270300.1 CDS ECH74115_1875 NC_011353.1 1772748 1773383 D identified by match to protein family HMM PF00877; tail assembly protein 1772748..1773383 Escherichia coli O157:H7 str. EC4115 6968558 YP_002270301.1 CDS ECH74115_1876 NC_011353.1 1773380 1773958 D identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1773380..1773958 Escherichia coli O157:H7 str. EC4115 6967464 YP_002270302.1 CDS ECH74115_1877 NC_011353.1 1774004 1774123 D identified by glimmer; hypothetical protein 1774004..1774123 Escherichia coli O157:H7 str. EC4115 6967019 YP_002270303.1 CDS ECH74115_1878 NC_011353.1 1774199 1777675 D identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 1774199..1777675 Escherichia coli O157:H7 str. EC4115 6971610 YP_002270304.1 CDS ECH74115_1879 NC_011353.1 1777743 1778342 D identified by match to protein family HMM PF06316; Ail/Lom family protein 1777743..1778342 Escherichia coli O157:H7 str. EC4115 6971124 YP_002270305.1 CDS ECH74115_1880 NC_011353.1 1778343 1778471 R hypothetical protein complement(1778343..1778471) Escherichia coli O157:H7 str. EC4115 6970246 YP_002270306.1 CDS ECH74115_1882 NC_011353.1 1779442 1779720 D identified by match to protein family HMM PF06820; tail fiber protein 1779442..1779720 Escherichia coli O157:H7 str. EC4115 6967362 YP_002270307.1 CDS ECH74115_1883 NC_011353.1 1779722 1779991 D prophage tail fiber C-terminus family protein 1779722..1779991 Escherichia coli O157:H7 str. EC4115 6966587 YP_002270308.1 CDS ECH74115_1884 NC_011353.1 1780445 1780948 D identified by match to protein family HMM PF03400; IS1, transposase orfB 1780445..1780948 Escherichia coli O157:H7 str. EC4115 6969053 YP_002270309.1 CDS ECH74115_1885 NC_011353.1 1781124 1781714 D OspG 1781124..1781714 Escherichia coli O157:H7 str. EC4115 6968412 YP_002270310.1 CDS ECH74115_1887 NC_011353.1 1782576 1782692 D hypothetical protein 1782576..1782692 Escherichia coli O157:H7 str. EC4115 6970360 YP_002270311.1 CDS ECH74115_1888 NC_011353.1 1782752 1783258 R identified by match to protein family HMM PF05974; hypothetical protein complement(1782752..1783258) Escherichia coli O157:H7 str. EC4115 6970097 YP_002270312.1 CDS yciF NC_011353.1 1783304 1783825 R identified by match to protein family HMM PF05974; YciF protein complement(1783304..1783825) Escherichia coli O157:H7 str. EC4115 6971616 YP_002270313.1 CDS ECH74115_1890 NC_011353.1 1783890 1784069 R hypothetical protein complement(1783890..1784069) Escherichia coli O157:H7 str. EC4115 6971292 YP_002270314.1 CDS ECH74115_1891 NC_011353.1 1784146 1784289 D identified by glimmer; hypothetical protein 1784146..1784289 Escherichia coli O157:H7 str. EC4115 6967791 YP_002270315.1 CDS trpA NC_011353.1 1784450 1785256 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1784450..1785256) Escherichia coli O157:H7 str. EC4115 6972001 YP_002270316.1 CDS trpB NC_011353.1 1785256 1786449 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1785256..1786449) Escherichia coli O157:H7 str. EC4115 6971209 YP_002270317.1 CDS trpC NC_011353.1 1786461 1787819 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1786461..1787819) Escherichia coli O157:H7 str. EC4115 6967389 YP_002270318.1 CDS trpD NC_011353.1 1787823 1789418 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1787823..1789418) Escherichia coli O157:H7 str. EC4115 6966745 YP_002270319.1 CDS trpE NC_011353.1 1789418 1790980 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1789418..1790980) Escherichia coli O157:H7 str. EC4115 6968646 YP_002270320.1 CDS ECH74115_1898 NC_011353.1 1791254 1792135 D identified by match to protein family HMM PF02811; phosphoesterase 1791254..1792135 Escherichia coli O157:H7 str. EC4115 6967974 YP_002270321.1 CDS ECH74115_1899 NC_011353.1 1792096 1792752 D identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; hypothetical protein 1792096..1792752 Escherichia coli O157:H7 str. EC4115 6969756 YP_002270322.1 CDS ECH74115_1900 NC_011353.1 1792780 1794363 D hypothetical protein 1792780..1794363 Escherichia coli O157:H7 str. EC4115 6972192 YP_002270323.1 CDS rluB NC_011353.1 1794576 1795448 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1794576..1795448 Escherichia coli O157:H7 str. EC4115 6970998 YP_002270324.1 CDS btuR NC_011353.1 1795488 1796078 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1795488..1796078) Escherichia coli O157:H7 str. EC4115 6967648 YP_002270325.1 CDS ECH74115_1903 NC_011353.1 1796075 1796833 R identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase complement(1796075..1796833) Escherichia coli O157:H7 str. EC4115 6969897 YP_002270326.1 CDS sohB NC_011353.1 1797053 1798102 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1797053..1798102 Escherichia coli O157:H7 str. EC4115 6970466 YP_002270327.1 CDS ECH74115_1905 NC_011353.1 1798138 1798389 R hypothetical protein complement(1798138..1798389) Escherichia coli O157:H7 str. EC4115 6968420 YP_002270328.1 CDS topA NC_011353.1 1798769 1801366 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1798769..1801366 Escherichia coli O157:H7 str. EC4115 6969066 YP_002270329.1 CDS cysB NC_011353.1 1801576 1802550 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1801576..1802550 Escherichia coli O157:H7 str. EC4115 6969509 YP_002270330.1 CDS ECH74115_1908 NC_011353.1 1802881 1803009 D hypothetical protein 1802881..1803009 Escherichia coli O157:H7 str. EC4115 6970298 YP_002270331.1 CDS ECH74115_1909 NC_011353.1 1803012 1803179 D hypothetical protein 1803012..1803179 Escherichia coli O157:H7 str. EC4115 6971111 YP_002270332.1 CDS acnA NC_011353.1 1803552 1806227 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1803552..1806227 Escherichia coli O157:H7 str. EC4115 6966973 YP_002270333.1 CDS ribA NC_011353.1 1806291 1806881 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1806291..1806881) Escherichia coli O157:H7 str. EC4115 6967690 YP_002270334.1 CDS pgpB NC_011353.1 1807051 1807815 D identified by match to protein family HMM PF01569; phosphatidylglycerophosphatase B 1807051..1807815 Escherichia coli O157:H7 str. EC4115 6968560 YP_002270335.1 CDS ECH74115_1913 NC_011353.1 1807964 1808272 D identified by match to protein family HMM PF06305; hypothetical protein 1807964..1808272 Escherichia coli O157:H7 str. EC4115 6969356 YP_002270336.1 CDS ECH74115_1914 NC_011353.1 1808279 1809448 D identified by match to protein family HMM PF07719; hypothetical protein 1808279..1809448 Escherichia coli O157:H7 str. EC4115 6968028 YP_002270337.1 CDS ECH74115_1915 NC_011353.1 1809482 1809622 R identified by glimmer; hypothetical protein complement(1809482..1809622) Escherichia coli O157:H7 str. EC4115 6967559 YP_002270338.1 CDS pyrF NC_011353.1 1809581 1810378 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1809581..1810378 Escherichia coli O157:H7 str. EC4115 6966727 YP_002270339.1 CDS ECH74115_1917 NC_011353.1 1810375 1810704 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1810375..1810704 Escherichia coli O157:H7 str. EC4115 6968945 YP_002270340.1 CDS ECH74115_1918 NC_011353.1 1810830 1811048 R lipoprotein complement(1810830..1811048) Escherichia coli O157:H7 str. EC4115 6968126 YP_002270341.1 CDS ECH74115_1919 NC_011353.1 1811317 1812066 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; DeoR family transcriptional regulator complement(1811317..1812066) Escherichia coli O157:H7 str. EC4115 6970816 YP_002270342.1 CDS ECH74115_1920 NC_011353.1 1812156 1812329 R hypothetical protein complement(1812156..1812329) Escherichia coli O157:H7 str. EC4115 6970778 YP_002270343.1 CDS rnb NC_011353.1 1814692 1816626 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1814692..1816626) Escherichia coli O157:H7 str. EC4115 6967607 YP_002270344.1 CDS ECH74115_1924 NC_011353.1 1816694 1817821 R hypothetical protein complement(1816694..1817821) Escherichia coli O157:H7 str. EC4115 6966873 YP_002270345.1 CDS fabI NC_011353.1 1817965 1818753 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1817965..1818753) Escherichia coli O157:H7 str. EC4115 6972122 YP_002270346.1 CDS eefR NC_011353.1 1819231 1819797 D identified by match to protein family HMM PF00440; transcriptional regulator EefR 1819231..1819797 Escherichia coli O157:H7 str. EC4115 6971318 YP_002270347.1 CDS eefA NC_011353.1 1819946 1821067 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; multidrug efflux transport protein EefA 1819946..1821067 Escherichia coli O157:H7 str. EC4115 6969458 YP_002270348.1 CDS eefC NC_011353.1 1824179 1825552 D identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845; multidrug efflux outer membrane protein EefC 1824179..1825552 Escherichia coli O157:H7 str. EC4115 6968165 YP_002270349.1 CDS eefD NC_011353.1 1825561 1826724 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710; multidrug efflux transport protein EefD 1825561..1826724 Escherichia coli O157:H7 str. EC4115 6967377 YP_002270350.1 CDS sapF NC_011353.1 1826776 1827582 R identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein SapF complement(1826776..1827582) Escherichia coli O157:H7 str. EC4115 6966979 YP_002270351.1 CDS sapD NC_011353.1 1827584 1828576 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; peptide ABC transporter ATP-binding protein SapD complement(1827584..1828576) Escherichia coli O157:H7 str. EC4115 6971887 YP_002270352.1 CDS sapC NC_011353.1 1828576 1829466 R identified by match to protein family HMM PF00528; peptide ABC transporter permease SapC complement(1828576..1829466) Escherichia coli O157:H7 str. EC4115 6971203 YP_002270353.1 CDS sapB NC_011353.1 1829453 1830418 R identified by match to protein family HMM PF00528; peptide ABC transporter permease SapB complement(1829453..1830418) Escherichia coli O157:H7 str. EC4115 6970804 YP_002270354.1 CDS sapA NC_011353.1 1830415 1832034 R identified by match to protein family HMM PF00496; peptide ABC transporter substrate-binding protein complement(1830415..1832034) Escherichia coli O157:H7 str. EC4115 6972225 YP_002270355.1 CDS ECH74115_1937 NC_011353.1 1832264 1832389 D identified by glimmer; hypothetical protein 1832264..1832389 Escherichia coli O157:H7 str. EC4115 6970905 YP_002270356.1 CDS ECH74115_1936 NC_011353.1 1832371 1832616 R hypothetical protein complement(1832371..1832616) Escherichia coli O157:H7 str. EC4115 6966558 YP_002270357.1 CDS ECH74115_1938 NC_011353.1 1832750 1834135 R identified by match to protein family HMM PF00324; amino acid permease complement(1832750..1834135) Escherichia coli O157:H7 str. EC4115 6967275 YP_002270358.1 CDS puuA NC_011353.1 1834438 1835856 R identified by match to protein family HMM PF00120; glutamate--putrescine ligase complement(1834438..1835856) Escherichia coli O157:H7 str. EC4115 6969682 YP_002270359.1 CDS puuD NC_011353.1 1836080 1836832 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1836080..1836832 Escherichia coli O157:H7 str. EC4115 6969742 YP_002270360.1 CDS puuR NC_011353.1 1836859 1837416 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1836859..1837416 Escherichia coli O157:H7 str. EC4115 6971986 YP_002270361.1 CDS puuC NC_011353.1 1837566 1839053 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1837566..1839053 Escherichia coli O157:H7 str. EC4115 6971505 YP_002270362.1 CDS puuB NC_011353.1 1839055 1840335 D identified by match to protein family HMM PF01266; gamma-glutamylputrescine oxidoreductase 1839055..1840335 Escherichia coli O157:H7 str. EC4115 6967736 YP_002270363.1 CDS gabT1 NC_011353.1 1840373 1841638 D putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1840373..1841638 Escherichia coli O157:H7 str. EC4115 6966924 YP_002270364.1 CDS pspF NC_011353.1 1841769 1842746 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1841769..1842746) Escherichia coli O157:H7 str. EC4115 6972105 YP_002270365.1 CDS pspA NC_011353.1 1842913 1843581 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1842913..1843581 Escherichia coli O157:H7 str. EC4115 6970924 YP_002270366.1 CDS pspB NC_011353.1 1843635 1843859 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1843635..1843859 Escherichia coli O157:H7 str. EC4115 6970434 YP_002270367.1 CDS pspC NC_011353.1 1843859 1844218 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1843859..1844218 Escherichia coli O157:H7 str. EC4115 6969612 YP_002270368.1 CDS pspD NC_011353.1 1844227 1844448 D identified by match to protein family HMM PF09584; match to protein family HMM TIGR02979; peripheral inner membrane phage-shock protein 1844227..1844448 Escherichia coli O157:H7 str. EC4115 6966782 YP_002270369.1 CDS pspE NC_011353.1 1844523 1844837 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1844523..1844837 Escherichia coli O157:H7 str. EC4115 6968441 YP_002270370.1 CDS ECH74115_1951 NC_011353.1 1844849 1844968 D identified by glimmer; hypothetical protein 1844849..1844968 Escherichia coli O157:H7 str. EC4115 6967920 YP_002270371.1 CDS ECH74115_1956 NC_011353.1 1848052 1848933 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; sugar ABC transporter permease 1848052..1848933 Escherichia coli O157:H7 str. EC4115 6968826 YP_002270372.1 CDS ECH74115_1957 NC_011353.1 1848920 1849762 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; sugar ABC transporter permease 1848920..1849762 Escherichia coli O157:H7 str. EC4115 6971184 YP_002270373.1 CDS ECH74115_1958 NC_011353.1 1849793 1850845 D identified by match to protein family HMM PF00107; oxidoreductase, zinc-binding dehydrogenase family 1849793..1850845 Escherichia coli O157:H7 str. EC4115 6967578 YP_002270374.1 CDS ECH74115_1959 NC_011353.1 1850863 1851651 D identified by match to protein family HMM PF01261; AP endonuclease, family 2 1850863..1851651 Escherichia coli O157:H7 str. EC4115 6969976 YP_002270375.1 CDS ECH74115_1960 NC_011353.1 1851661 1852716 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; gfo/idh/mocA family protein 1851661..1852716 Escherichia coli O157:H7 str. EC4115 6972158 YP_002270376.1 CDS ECH74115_1961 NC_011353.1 1852713 1854980 D identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; glycoside hydrolase 1852713..1854980 Escherichia coli O157:H7 str. EC4115 6968804 YP_002270377.1 CDS pgmB NC_011353.1 1854977 1855636 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009; beta-phosphoglucomutase 1854977..1855636 Escherichia coli O157:H7 str. EC4115 6968027 YP_002270378.1 CDS ECH74115_1963 NC_011353.1 1855650 1856732 D identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; sugar ABC transporter ATP-binding protein 1855650..1856732 Escherichia coli O157:H7 str. EC4115 6971689 YP_002270379.1 CDS ompG NC_011353.1 1856777 1857682 D identified by match to protein family HMM PF09381; outer membrane protein G 1856777..1857682 Escherichia coli O157:H7 str. EC4115 6970014 YP_002270380.1 CDS ECH74115_1965 NC_011353.1 1857793 1858791 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator complement(1857793..1858791) Escherichia coli O157:H7 str. EC4115 6966570 YP_002270381.1 CDS ECH74115_1966 NC_011353.1 1858946 1860343 D identified by match to protein family HMM PF04317; hypothetical protein 1858946..1860343 Escherichia coli O157:H7 str. EC4115 6967381 YP_002270382.1 CDS ECH74115_1967 NC_011353.1 1860340 1861401 D identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein 1860340..1861401 Escherichia coli O157:H7 str. EC4115 6968217 YP_002270383.1 CDS tyrR NC_011353.1 1861549 1863090 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1861549..1863090 Escherichia coli O157:H7 str. EC4115 6968942 YP_002270384.1 CDS tpx NC_011353.1 1863134 1863640 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1863134..1863640) Escherichia coli O157:H7 str. EC4115 6968661 YP_002270385.1 CDS ECH74115_1971 NC_011353.1 1863759 1864724 D identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing protein 1863759..1864724 Escherichia coli O157:H7 str. EC4115 6969100 YP_002270386.1 CDS ECH74115_1970 NC_011353.1 1864699 1865427 R identified by match to protein family HMM PF00246; murein peptide amidase A complement(1864699..1865427) Escherichia coli O157:H7 str. EC4115 6970177 YP_002270387.1 CDS ECH74115_1972 NC_011353.1 1865718 1866356 R NmrA family protein complement(1865718..1866356) Escherichia coli O157:H7 str. EC4115 6969532 YP_002270388.1 CDS ECH74115_1975 NC_011353.1 1867307 1868227 R identified by match to protein family HMM PF02129; hypothetical protein complement(1867307..1868227) Escherichia coli O157:H7 str. EC4115 6970836 YP_002270389.1 CDS ECH74115_1976 NC_011353.1 1868365 1869264 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1868365..1869264 Escherichia coli O157:H7 str. EC4115 6971235 YP_002270390.1 CDS mppA NC_011353.1 1869600 1871213 D identified by match to protein family HMM PF00496; periplasmic murein peptide-binding protein 1869600..1871213 Escherichia coli O157:H7 str. EC4115 6972121 YP_002270391.1 CDS ECH74115_1978 NC_011353.1 1871264 1872295 R identified by match to protein family HMM PF00924; transporter small conductance mechanosensitive ion channel family complement(1871264..1872295) Escherichia coli O157:H7 str. EC4115 6967536 YP_002270392.1 CDS ECH74115_1979 NC_011353.1 1872539 1872796 D hypothetical protein 1872539..1872796 Escherichia coli O157:H7 str. EC4115 6968347 YP_002270393.1 CDS uspE NC_011353.1 1872846 1873796 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1872846..1873796) Escherichia coli O157:H7 str. EC4115 6968755 YP_002270394.1 CDS fnr NC_011353.1 1873948 1874700 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1873948..1874700) Escherichia coli O157:H7 str. EC4115 6969598 YP_002270395.1 CDS ogt NC_011353.1 1874895 1875410 R identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589; O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1874895..1875410) Escherichia coli O157:H7 str. EC4115 6970729 YP_002270396.1 CDS abgT NC_011353.1 1875421 1876953 R identified by match to protein family HMM PF03806; match to protein family HMM TIGR00819; aminobenzoyl-glutamate transporter complement(1875421..1876953) Escherichia coli O157:H7 str. EC4115 6970902 YP_002270397.1 CDS abgB NC_011353.1 1876984 1878429 R identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein B complement(1876984..1878429) Escherichia coli O157:H7 str. EC4115 6970418 YP_002270398.1 CDS abgA NC_011353.1 1878429 1879739 R identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein A complement(1878429..1879739) Escherichia coli O157:H7 str. EC4115 6969625 YP_002270399.1 CDS ECH74115_1986 NC_011353.1 1879915 1880823 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 1879915..1880823 Escherichia coli O157:H7 str. EC4115 6968503 YP_002270400.1 CDS ECH74115_1988 NC_011353.1 1881153 1881716 D identified by match to protein family HMM PF01713; Smr domain-containing protein 1881153..1881716 Escherichia coli O157:H7 str. EC4115 6972291 YP_002270401.1 CDS ECH74115_1989 NC_011353.1 1881737 1883029 R identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box-containing diguanylate cyclase complement(1881737..1883029) Escherichia coli O157:H7 str. EC4115 6966559 YP_002270402.1 CDS zntB NC_011353.1 1883224 1884207 D identified by match to protein family HMM PF01544; zinc transporter 1883224..1884207 Escherichia coli O157:H7 str. EC4115 6972166 YP_002270403.1 CDS dbpA NC_011353.1 1884685 1886058 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1884685..1886058 Escherichia coli O157:H7 str. EC4115 6972288 YP_002270404.1 CDS ECH74115_1993 NC_011353.1 1886187 1887122 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1886187..1887122) Escherichia coli O157:H7 str. EC4115 6970333 YP_002270405.1 CDS uspF NC_011353.1 1887298 1887732 R identified by match to protein family HMM PF00582; universal stress protein F complement(1887298..1887732) Escherichia coli O157:H7 str. EC4115 6969704 YP_002270406.1 CDS ydbK NC_011353.1 1889352 1892876 R identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate-flavodoxin oxidoreductase complement(1889352..1892876) Escherichia coli O157:H7 str. EC4115 6972301 YP_002270407.1 CDS ECH74115_1999 NC_011353.1 1892947 1893063 R identified by glimmer; hypothetical protein complement(1892947..1893063) Escherichia coli O157:H7 str. EC4115 6972011 YP_002270408.1 CDS ECH74115_2001 NC_011353.1 1893291 1893416 D lipoprotein 1893291..1893416 Escherichia coli O157:H7 str. EC4115 6971196 YP_002270409.1 CDS hslJ NC_011353.1 1893413 1893835 R identified by match to protein family HMM PF03724; heat-inducible protein complement(1893413..1893835) Escherichia coli O157:H7 str. EC4115 6968955 YP_002270410.1 CDS idhA NC_011353.1 1893946 1894935 R identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-lactate dehydrogenase complement(1893946..1894935) Escherichia coli O157:H7 str. EC4115 6966898 YP_002270411.1 CDS ECH74115_2003 NC_011353.1 1895143 1897782 D identified by glimmer; hypothetical protein 1895143..1897782 Escherichia coli O157:H7 str. EC4115 6968152 YP_002270412.1 CDS ECH74115_2004 NC_011353.1 1897779 1897964 D lipoprotein 1897779..1897964 Escherichia coli O157:H7 str. EC4115 6970251 YP_002270413.1 CDS ECH74115_2005 NC_011353.1 1897972 1898295 D identified by match to protein family HMM PF07027; hypothetical protein 1897972..1898295 Escherichia coli O157:H7 str. EC4115 6971674 YP_002270414.1 CDS ECH74115_2008 NC_011353.1 1904643 1905503 D identified by match to protein family HMM PF00248; oxidoreductase 1904643..1905503 Escherichia coli O157:H7 str. EC4115 6969963 YP_002270415.1 CDS ECH74115_2009 NC_011353.1 1905484 1905597 D identified by glimmer; hypothetical protein 1905484..1905597 Escherichia coli O157:H7 str. EC4115 6969570 YP_002270416.1 CDS ECH74115_2010 NC_011353.1 1905567 1907873 D identified by glimmer; hypothetical protein 1905567..1907873 Escherichia coli O157:H7 str. EC4115 6970392 YP_002270417.1 CDS ECH74115_2011 NC_011353.1 1908044 1908649 D identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 1908044..1908649 Escherichia coli O157:H7 str. EC4115 6971642 YP_002270418.1 CDS cdsA2 NC_011353.1 1908649 1909545 D identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1908649..1909545 Escherichia coli O157:H7 str. EC4115 6966756 YP_002270419.1 CDS ECH74115_2013 NC_011353.1 1909561 1911318 D hypothetical protein 1909561..1911318 Escherichia coli O157:H7 str. EC4115 6967915 YP_002270420.1 CDS ECH74115_2014 NC_011353.1 1911332 1912624 D identified by match to protein family HMM PF00782; match to protein family HMM PF01569; PAP2 family protein 1911332..1912624 Escherichia coli O157:H7 str. EC4115 6967980 YP_002270421.1 CDS azoR NC_011353.1 1912675 1913280 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1912675..1913280) Escherichia coli O157:H7 str. EC4115 6969985 YP_002270422.1 CDS hrpA NC_011353.1 1913481 1917383 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1913481..1917383 Escherichia coli O157:H7 str. EC4115 6971329 YP_002270423.1 CDS ECH74115_2017 NC_011353.1 1918115 1918297 D hypothetical protein 1918115..1918297 Escherichia coli O157:H7 str. EC4115 6971942 YP_002270424.1 CDS ECH74115_2018 NC_011353.1 1918284 1918715 D hypothetical protein 1918284..1918715 Escherichia coli O157:H7 str. EC4115 6970127 YP_002270425.1 CDS ECH74115_2019 NC_011353.1 1919104 1919217 D hypothetical protein 1919104..1919217 Escherichia coli O157:H7 str. EC4115 6970754 YP_002270426.1 CDS ECH74115_2020 NC_011353.1 1919333 1920133 D identified by match to protein family HMM PF02698; hypothetical protein 1919333..1920133 Escherichia coli O157:H7 str. EC4115 6968876 YP_002270427.1 CDS aldA NC_011353.1 1920330 1921769 D NAD-linked; aldehyde dehydrogenase A 1920330..1921769 Escherichia coli O157:H7 str. EC4115 6966843 YP_002270428.1 CDS gapC NC_011353.1 1921811 1922812 R identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase complement(1921811..1922812) Escherichia coli O157:H7 str. EC4115 6967263 YP_002270429.1 CDS ECH74115_2023 NC_011353.1 1923001 1923531 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1923001..1923531 Escherichia coli O157:H7 str. EC4115 6970944 YP_002270430.1 CDS ECH74115_2025 NC_011353.1 1923776 1923949 D hypothetical protein 1923776..1923949 Escherichia coli O157:H7 str. EC4115 6972293 YP_002270431.1 CDS trg NC_011353.1 1924797 1926209 D identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein III 1924797..1926209 Escherichia coli O157:H7 str. EC4115 6970117 YP_002270432.1 CDS ECH74115_2027 NC_011353.1 1926247 1927170 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(1926247..1927170) Escherichia coli O157:H7 str. EC4115 6971539 YP_002270433.1 CDS ECH74115_2028 NC_011353.1 1927387 1928730 D identified by match to protein family HMM PF07063; hypothetical protein 1927387..1928730 Escherichia coli O157:H7 str. EC4115 6966838 YP_002270434.1 CDS mdoD NC_011353.1 1928991 1930610 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1928991..1930610 Escherichia coli O157:H7 str. EC4115 6967079 YP_002270435.1 CDS ECH74115_2030 NC_011353.1 1930750 1930974 D identified by match to protein family HMM PF04325; hypothetical protein 1930750..1930974 Escherichia coli O157:H7 str. EC4115 6967861 YP_002270436.1 CDS ECH74115_2032 NC_011353.1 1931568 1932548 R hypothetical protein complement(1931568..1932548) Escherichia coli O157:H7 str. EC4115 6971136 YP_002270437.1 CDS tehA NC_011353.1 1932672 1933664 D identified by match to protein family HMM PF03595; match to protein family HMM TIGR00816; potassium-tellurite ethidium and proflavin transporter 1932672..1933664 Escherichia coli O157:H7 str. EC4115 6970361 YP_002270438.1 CDS tehB NC_011353.1 1933661 1934254 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1933661..1934254 Escherichia coli O157:H7 str. EC4115 6966885 YP_002270439.1 CDS ECH74115_2036 NC_011353.1 1934558 1935226 D lipoprotein 1934558..1935226 Escherichia coli O157:H7 str. EC4115 6967321 YP_002270440.1 CDS ECH74115_2039 NC_011353.1 1936526 1937062 D identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 1936526..1937062 Escherichia coli O157:H7 str. EC4115 6968511 YP_002270441.1 CDS ECH74115_2040 NC_011353.1 1937093 1939096 D identified by match to protein family HMM PF01136; U32 family peptidase 1937093..1939096 Escherichia coli O157:H7 str. EC4115 6968741 YP_002270442.1 CDS ECH74115_2041 NC_011353.1 1939188 1939358 R hypothetical protein complement(1939188..1939358) Escherichia coli O157:H7 str. EC4115 6966857 YP_002270443.1 CDS ECH74115_2042 NC_011353.1 1939475 1939597 R identified by glimmer; hypothetical protein complement(1939475..1939597) Escherichia coli O157:H7 str. EC4115 6967451 YP_002270444.1 CDS ECH74115_2043 NC_011353.1 1939841 1940278 D identified by match to protein family HMM PF01381; match to protein family HMM PF03681; hypothetical protein 1939841..1940278 Escherichia coli O157:H7 str. EC4115 6971998 YP_002270445.1 CDS ECH74115_2044 NC_011353.1 1940357 1941763 D identified by match to protein family HMM PF00155; match to protein family HMM PF00392; transcriptional regulator, GntR family/aminotransferase, classes I and II 1940357..1941763 Escherichia coli O157:H7 str. EC4115 6969741 YP_002270446.1 CDS ydcS NC_011353.1 1942008 1943153 D identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 1942008..1943153 Escherichia coli O157:H7 str. EC4115 6970725 YP_002270447.1 CDS ydcT NC_011353.1 1943171 1944184 D identified by match to protein family HMM PF00005; match to protein family HMM PF08402; ABC transporter ATP-binding protein 1943171..1944184 Escherichia coli O157:H7 str. EC4115 6968166 YP_002270448.1 CDS ydcU NC_011353.1 1944185 1945126 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 1944185..1945126 Escherichia coli O157:H7 str. EC4115 6969116 YP_002270449.1 CDS ydcV NC_011353.1 1945116 1945910 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 1945116..1945910 Escherichia coli O157:H7 str. EC4115 6968332 YP_002270450.1 CDS ydcW NC_011353.1 1945932 1947356 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1945932..1947356 Escherichia coli O157:H7 str. EC4115 6967839 YP_002270451.1 CDS ECH74115_2049 NC_011353.1 1947353 1947469 R identified by glimmer; hypothetical protein complement(1947353..1947469) Escherichia coli O157:H7 str. EC4115 6970864 YP_002270452.1 CDS ECH74115_2051 NC_011353.1 1947695 1947916 D hypothetical protein 1947695..1947916 Escherichia coli O157:H7 str. EC4115 6971671 YP_002270453.1 CDS ECH74115_2052 NC_011353.1 1948002 1948235 D hypothetical protein 1948002..1948235 Escherichia coli O157:H7 str. EC4115 6970396 YP_002270454.1 CDS ECH74115_2053 NC_011353.1 1948236 1948685 R identified by match to protein family HMM PF04657; hypothetical protein complement(1948236..1948685) Escherichia coli O157:H7 str. EC4115 6969562 YP_002270455.1 CDS ECH74115_2054 NC_011353.1 1948682 1949263 R identified by match to protein family HMM PF00583; GNAT family acetyltransferase complement(1948682..1949263) Escherichia coli O157:H7 str. EC4115 6969106 YP_002270456.1 CDS ECH74115_2055 NC_011353.1 1949381 1950418 D identified by match to protein family HMM PF00107; oxidoreductase, zinc-binding dehydrogenase family 1949381..1950418 Escherichia coli O157:H7 str. EC4115 6968641 YP_002270457.1 CDS ECH74115_2056 NC_011353.1 1950616 1951281 D identified by match to protein family HMM PF00392; match to protein family HMM PF07729; DNA-binding transcriptional regulator 1950616..1951281 Escherichia coli O157:H7 str. EC4115 6967718 YP_002270458.1 CDS ECH74115_2057 NC_011353.1 1951317 1953419 R identified by match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor complement(1951317..1953419) Escherichia coli O157:H7 str. EC4115 6969337 YP_002270459.1 CDS ECH74115_2058 NC_011353.1 1953661 1954722 D hypothetical protein 1953661..1954722 Escherichia coli O157:H7 str. EC4115 6969379 YP_002270460.1 CDS ansP NC_011353.1 1954837 1956336 R identified by match to protein family HMM PF00324; L-asparagine permease complement(1954837..1956336) Escherichia coli O157:H7 str. EC4115 6970186 YP_002270461.1 CDS ECH74115_2060 NC_011353.1 1956406 1956555 D identified by glimmer; hypothetical protein 1956406..1956555 Escherichia coli O157:H7 str. EC4115 6967700 YP_002270462.1 CDS ECH74115_2061 NC_011353.1 1956603 1957220 D transferase 1956603..1957220 Escherichia coli O157:H7 str. EC4115 6968572 YP_002270463.1 CDS ECH74115_2062 NC_011353.1 1957389 1957508 D hypothetical protein 1957389..1957508 Escherichia coli O157:H7 str. EC4115 6966964 YP_002270464.1 CDS ECH74115_2063 NC_011353.1 1957921 1958067 R identified by glimmer; hypothetical protein complement(1957921..1958067) Escherichia coli O157:H7 str. EC4115 6967728 YP_002270465.1 CDS ECH74115_2064 NC_011353.1 1958329 1960437 D identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 1958329..1960437 Escherichia coli O157:H7 str. EC4115 6970938 YP_002270466.1 CDS ECH74115_2065 NC_011353.1 1960504 1964706 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsD 1960504..1964706 Escherichia coli O157:H7 str. EC4115 6971881 YP_002270467.1 CDS ECH74115_2070 NC_011353.1 1966888 1967115 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1966888..1967115 Escherichia coli O157:H7 str. EC4115 6972143 YP_002270468.1 CDS ECH74115_2074 NC_011353.1 1968801 1969694 R identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654; hypothetical protein complement(1968801..1969694) Escherichia coli O157:H7 str. EC4115 6968953 YP_002270469.1 CDS narV NC_011353.1 1969773 1970453 R identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase 2 subunit gamma complement(1969773..1970453) Escherichia coli O157:H7 str. EC4115 6968135 YP_002270470.1 CDS narW NC_011353.1 1970450 1971145 R identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 2 complement(1970450..1971145) Escherichia coli O157:H7 str. EC4115 6971798 YP_002270471.1 CDS narY NC_011353.1 1971145 1972689 R identified by match to protein family HMM TIGR01660; nitrate reductase 2 subunit beta complement(1971145..1972689) Escherichia coli O157:H7 str. EC4115 6971823 YP_002270472.1 CDS narZ NC_011353.1 1972686 1976426 R identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase 2 subunit alpha complement(1972686..1976426) Escherichia coli O157:H7 str. EC4115 6972037 YP_002270473.1 CDS narU NC_011353.1 1976508 1977896 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 2 complement(1976508..1977896) Escherichia coli O157:H7 str. EC4115 6969977 YP_002270474.1 CDS ECH74115_2080 NC_011353.1 1978202 1979461 R leucine-rich repeat protein complement(1978202..1979461) Escherichia coli O157:H7 str. EC4115 6970802 YP_002270475.1 CDS ECH74115_2083 NC_011353.1 1980951 1982051 R identified by match to protein family HMM PF00267; gram-negative porin family protein complement(1980951..1982051) Escherichia coli O157:H7 str. EC4115 6966731 YP_002270476.1 CDS ECH74115_2084 NC_011353.1 1982310 1983191 R identified by match to protein family HMM PF00892; hypothetical protein complement(1982310..1983191) Escherichia coli O157:H7 str. EC4115 6967334 YP_002270477.1 CDS fdnH NC_011353.1 1986489 1987367 D identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 1986489..1987367 Escherichia coli O157:H7 str. EC4115 6969342 YP_002270478.1 CDS fdnI NC_011353.1 1987360 1988013 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1987360..1988013 Escherichia coli O157:H7 str. EC4115 6969158 YP_002270479.1 CDS ECH74115_2089 NC_011353.1 1988241 1988525 R identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; HigA family addiction module antidote protein complement(1988241..1988525) Escherichia coli O157:H7 str. EC4115 6969762 YP_002270480.1 CDS ECH74115_2090 NC_011353.1 1988671 1989681 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1988671..1989681) Escherichia coli O157:H7 str. EC4115 6970393 YP_002270481.1 CDS sfcA NC_011353.1 1989815 1991512 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1989815..1991512) Escherichia coli O157:H7 str. EC4115 6966887 YP_002270482.1 CDS rpsV NC_011353.1 1991669 1991806 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1991669..1991806) Escherichia coli O157:H7 str. EC4115 6967452 YP_002270483.1 CDS ECH74115_2093 NC_011353.1 1991908 1992123 R biofilm-dependent modulation protein complement(1991908..1992123) Escherichia coli O157:H7 str. EC4115 6968080 YP_002270484.1 CDS osmC NC_011353.1 1992468 1992899 D identified by match to protein family HMM PF02566; match to protein family HMM TIGR03562; peroxiredoxin OsmC 1992468..1992899 Escherichia coli O157:H7 str. EC4115 6968700 YP_002270485.1 CDS ECH74115_2095 NC_011353.1 1992955 1993881 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein complement(1992955..1993881) Escherichia coli O157:H7 str. EC4115 6969459 YP_002270486.1 CDS ECH74115_2096 NC_011353.1 1993874 1994860 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein complement(1993874..1994860) Escherichia coli O157:H7 str. EC4115 6968880 YP_002270487.1 CDS yddQ NC_011353.1 1994857 1995753 R identified by match to protein family HMM PF00528; ATP-dependent peptide transporter membrane subunit complement(1994857..1995753) Escherichia coli O157:H7 str. EC4115 6967173 YP_002270488.1 CDS yddR NC_011353.1 1995750 1996772 R identified by match to protein family HMM PF00528; inner membrane ABC transporter permease yddR complement(1995750..1996772) Escherichia coli O157:H7 str. EC4115 6969046 YP_002270489.1 CDS ECH74115_2099 NC_011353.1 1996774 1998324 R identified by match to protein family HMM PF00496; ABC transporter periplasmic-binding protein yddS precursor complement(1996774..1998324) Escherichia coli O157:H7 str. EC4115 6970214 YP_002270490.1 CDS ddpX NC_011353.1 1998338 1998919 R catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase complement(1998338..1998919) Escherichia coli O157:H7 str. EC4115 6969414 YP_002270491.1 CDS ECH74115_2103 NC_011353.1 2001591 2002973 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(2001591..2002973) Escherichia coli O157:H7 str. EC4115 6967635 YP_002270492.1 CDS ECH74115_2104 NC_011353.1 2003350 2004564 R identified by match to protein family HMM PF02638; lipoprotein complement(2003350..2004564) Escherichia coli O157:H7 str. EC4115 6967012 YP_002270493.1 CDS gadC NC_011353.1 2004800 2006335 R identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910; glutamate:gamma aminobutyrate antiporter complement(2004800..2006335) Escherichia coli O157:H7 str. EC4115 6967603 YP_002270494.1 CDS gadA NC_011353.1 2006491 2007891 R identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase complement(2006491..2007891) Escherichia coli O157:H7 str. EC4115 6966988 YP_002270495.1 CDS pqqL NC_011353.1 2008252 2011035 R identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16B family complement(2008252..2011035) Escherichia coli O157:H7 str. EC4115 6970514 YP_002270496.1 CDS ECH74115_2108 NC_011353.1 2011092 2013464 R identified by match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor complement(2011092..2013464) Escherichia coli O157:H7 str. EC4115 6969872 YP_002270497.1 CDS ECH74115_2109 NC_011353.1 2013502 2015187 R identified by match to protein family HMM PF00005; match to protein family HMM PF05992; match to protein family HMM PF06472; inner membrane ABC transporter ATP-binding protein complement(2013502..2015187) Escherichia coli O157:H7 str. EC4115 6968145 YP_002270498.1 CDS ECH74115_2110 NC_011353.1 2015478 2016635 R identified by match to protein family HMM PF04055; radical SAM domain-containing protein complement(2015478..2016635) Escherichia coli O157:H7 str. EC4115 6970389 YP_002270499.1 CDS ECH74115_2112 NC_011353.1 2018773 2019534 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(2018773..2019534) Escherichia coli O157:H7 str. EC4115 6967641 YP_002270500.1 CDS ECH74115_2113 NC_011353.1 2019608 2019790 R hypothetical protein complement(2019608..2019790) Escherichia coli O157:H7 str. EC4115 6967039 YP_002270501.1 CDS ECH74115_2114 NC_011353.1 2020053 2022332 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase complement(2020053..2022332) Escherichia coli O157:H7 str. EC4115 6971824 YP_002270502.1 CDS ECH74115_2115 NC_011353.1 2022666 2023580 R identified by match to protein family HMM PF00419; match to protein family HMM PF09160; FimH-like protein complement(2022666..2023580) Escherichia coli O157:H7 str. EC4115 6971913 YP_002270503.1 CDS ECH74115_2116 NC_011353.1 2023640 2023930 R FimG-like protein complement(2023640..2023930) Escherichia coli O157:H7 str. EC4115 6967053 YP_002270504.1 CDS ECH74115_2117 NC_011353.1 2024156 2024686 R identified by match to protein family HMM PF00419; FimF-like protein complement(2024156..2024686) Escherichia coli O157:H7 str. EC4115 6971980 YP_002270505.1 CDS ECH74115_2118 NC_011353.1 2024700 2026922 R identified by match to protein family HMM PF00577; fimbrial usher family protein complement(2024700..2026922) Escherichia coli O157:H7 str. EC4115 6968645 YP_002270506.1 CDS ECH74115_2119 NC_011353.1 2027393 2028103 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein complement(2027393..2028103) Escherichia coli O157:H7 str. EC4115 6967349 YP_002270507.1 CDS ECH74115_2120 NC_011353.1 2028464 2029027 R identified by match to protein family HMM PF00419; fimbrial protein complement(2028464..2029027) Escherichia coli O157:H7 str. EC4115 6970203 YP_002270508.1 CDS ECH74115_2121 NC_011353.1 2030001 2031056 R identified by match to protein family HMM PF07804; match to protein family HMM PF07805; protein HipA complement(2030001..2031056) Escherichia coli O157:H7 str. EC4115 6969395 YP_002270509.1 CDS ECH74115_2123 NC_011353.1 2032578 2036471 R identified by glimmer; lipoprotein complement(2032578..2036471) Escherichia coli O157:H7 str. EC4115 6971060 YP_002270510.1 CDS lsrK NC_011353.1 2037140 2038732 R identified by match to protein family HMM PF00370; match to protein family HMM PF02782; autoinducer-2 (AI-2) kinase complement(2037140..2038732) Escherichia coli O157:H7 str. EC4115 6972230 YP_002270511.1 CDS lsrR NC_011353.1 2038811 2039764 R identified by match to protein family HMM PF04198; transcriptional repressor LsrR complement(2038811..2039764) Escherichia coli O157:H7 str. EC4115 6971400 YP_002270512.1 CDS lsrA NC_011353.1 2040013 2041548 D identified by match to protein family HMM PF00005; autoinducer-2 ABC transporter ATP-binding protein LsrA 2040013..2041548 Escherichia coli O157:H7 str. EC4115 6968979 YP_002270513.1 CDS lsrC NC_011353.1 2041542 2042570 D identified by match to protein family HMM PF02653; autoinducer-2 ABC transporter permease LsrC 2041542..2042570 Escherichia coli O157:H7 str. EC4115 6966590 YP_002270514.1 CDS lsrD NC_011353.1 2042570 2043562 D identified by match to protein family HMM PF02653; autoinducer-2 ABC transporter permease LsrD 2042570..2043562 Escherichia coli O157:H7 str. EC4115 6969980 YP_002270515.1 CDS lsrB NC_011353.1 2043574 2044596 D autoinducer-2 ABC transporter periplasmic autoinducer-2-binding protein LsrB 2043574..2044596 Escherichia coli O157:H7 str. EC4115 6970787 YP_002270516.1 CDS lsrF NC_011353.1 2044623 2045498 D identified by match to protein family HMM PF01791; aldolase 2044623..2045498 Escherichia coli O157:H7 str. EC4115 6972193 YP_002270517.1 CDS lsrG NC_011353.1 2045522 2045812 D identified by match to protein family HMM PF03992; autoinducer-2 (AI-2) modifying protein LsrG 2045522..2045812 Escherichia coli O157:H7 str. EC4115 6969764 YP_002270518.1 CDS tam NC_011353.1 2045869 2046627 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 2045869..2046627 Escherichia coli O157:H7 str. EC4115 6967738 YP_002270519.1 CDS ECH74115_2133 NC_011353.1 2046631 2047545 R identified by match to protein family HMM PF05249; hypothetical protein complement(2046631..2047545) Escherichia coli O157:H7 str. EC4115 6971004 YP_002270520.1 CDS uxaB NC_011353.1 2047742 2049193 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(2047742..2049193) Escherichia coli O157:H7 str. EC4115 6966726 YP_002270521.1 CDS ECH74115_2135 NC_011353.1 2049420 2050838 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(2049420..2050838) Escherichia coli O157:H7 str. EC4115 6967530 YP_002270522.1 CDS ECH74115_2136 NC_011353.1 2050977 2051336 R hypothetical protein complement(2050977..2051336) Escherichia coli O157:H7 str. EC4115 6967539 YP_002270523.1 CDS glsA2 NC_011353.1 2051336 2052262 R catalyzes the formation of glutamate from glutamine; glutaminase complement(2051336..2052262) Escherichia coli O157:H7 str. EC4115 6966735 YP_002270524.1 CDS ECH74115_2138 NC_011353.1 2052326 2053714 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(2052326..2053714) Escherichia coli O157:H7 str. EC4115 6968805 YP_002270525.1 CDS ECH74115_2139 NC_011353.1 2053815 2054696 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2053815..2054696 Escherichia coli O157:H7 str. EC4115 6968012 YP_002270526.1 CDS sotB NC_011353.1 2056040 2057230 D identified by match to protein family HMM PF07690; sugar efflux transporter 2056040..2057230 Escherichia coli O157:H7 str. EC4115 6971914 YP_002270527.1 CDS marC NC_011353.1 2057255 2057920 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(2057255..2057920) Escherichia coli O157:H7 str. EC4115 6971507 YP_002270528.1 CDS marR NC_011353.1 2058132 2058566 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 2058132..2058566 Escherichia coli O157:H7 str. EC4115 6967059 YP_002270529.1 CDS marA NC_011353.1 2058586 2058969 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 2058586..2058969 Escherichia coli O157:H7 str. EC4115 6971943 YP_002270530.1 CDS marB NC_011353.1 2059001 2059219 D hypothetical protein 2059001..2059219 Escherichia coli O157:H7 str. EC4115 6967771 YP_002270531.1 CDS eamA NC_011353.1 2059250 2060149 R identified by match to protein family HMM PF00892; match to protein family HMM PF03151; O-acetylserine/cysteine export protein complement(2059250..2060149) Escherichia coli O157:H7 str. EC4115 6967176 YP_002270532.1 CDS ECH74115_2148 NC_011353.1 2060344 2061531 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 2060344..2061531 Escherichia coli O157:H7 str. EC4115 6971139 YP_002270533.1 CDS ECH74115_2149 NC_011353.1 2061572 2061967 R rhodanese domain-containing protein complement(2061572..2061967) Escherichia coli O157:H7 str. EC4115 6970021 YP_002270534.1 CDS ftrA NC_011353.1 2062041 2063033 D upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrA 2062041..2063033 Escherichia coli O157:H7 str. EC4115 6971711 YP_002270535.1 CDS ECH74115_2151 NC_011353.1 2063455 2064345 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein complement(2063455..2064345) Escherichia coli O157:H7 str. EC4115 6968539 YP_002270536.1 CDS ECH74115_2152 NC_011353.1 2064600 2064992 R identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein complement(2064600..2064992) Escherichia coli O157:H7 str. EC4115 6970480 YP_002270537.1 CDS ECH74115_2153 NC_011353.1 2065268 2065786 D identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A 2065268..2065786 Escherichia coli O157:H7 str. EC4115 6968719 YP_002270538.1 CDS dcp NC_011353.1 2065831 2067876 R identified by match to protein family HMM PF01432; dipeptidyl carboxypeptidase II complement(2065831..2067876) Escherichia coli O157:H7 str. EC4115 6968120 YP_002270539.1 CDS ECH74115_2155 NC_011353.1 2068013 2068759 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 2068013..2068759 Escherichia coli O157:H7 str. EC4115 6967919 YP_002270540.1 CDS ECH74115_2156 NC_011353.1 2068848 2069534 D identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 2068848..2069534 Escherichia coli O157:H7 str. EC4115 6967146 YP_002270541.1 CDS ECH74115_2157 NC_011353.1 2069711 2069914 D identified by match to protein family HMM TIGR03318; hypothetical protein 2069711..2069914 Escherichia coli O157:H7 str. EC4115 6969162 YP_002270542.1 CDS ECH74115_2158 NC_011353.1 2069950 2071410 R identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase family protein complement(2069950..2071410) Escherichia coli O157:H7 str. EC4115 6968327 YP_002270543.1 CDS ydfJ NC_011353.1 2071499 2072782 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; inner membrane metabolite transport protein ydfJ complement(2071499..2072782) Escherichia coli O157:H7 str. EC4115 6971089 YP_002270544.1 CDS ECH74115_2160 NC_011353.1 2072950 2073156 D identified by match to protein family HMM PF06183; hypothetical protein 2072950..2073156 Escherichia coli O157:H7 str. EC4115 6970201 YP_002270545.1 CDS ECH74115_2161 NC_011353.1 2073318 2073959 R identified by match to protein family HMM PF06416; hypothetical protein complement(2073318..2073959) Escherichia coli O157:H7 str. EC4115 6966591 YP_002270546.1 CDS ECH74115_2162 NC_011353.1 2074041 2074442 R identified by match to protein family HMM PF06416; hypothetical protein complement(2074041..2074442) Escherichia coli O157:H7 str. EC4115 6972196 YP_002270547.1 CDS ECH74115_2163 NC_011353.1 2074743 2075078 R identified by match to protein family HMM PF06416; non-LEE-encoded effector NleG complement(2074743..2075078) Escherichia coli O157:H7 str. EC4115 6968091 YP_002270548.1 CDS ECH74115_2164 NC_011353.1 2075432 2075701 R identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein complement(2075432..2075701) Escherichia coli O157:H7 str. EC4115 6967502 YP_002270549.1 CDS ECH74115_2165 NC_011353.1 2075703 2077016 R identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein complement(2075703..2077016) Escherichia coli O157:H7 str. EC4115 6970659 YP_002270550.1 CDS ECH74115_2166 NC_011353.1 2077081 2077680 R identified by match to protein family HMM PF06316; Ail/Lom family protein complement(2077081..2077680) Escherichia coli O157:H7 str. EC4115 6969956 YP_002270551.1 CDS ECH74115_2167 NC_011353.1 2077748 2080261 R identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein complement(2077748..2080261) Escherichia coli O157:H7 str. EC4115 6967986 YP_002270552.1 CDS ECH74115_2168 NC_011353.1 2080258 2081826 R host specificity protein complement(2080258..2081826) Escherichia coli O157:H7 str. EC4115 6970387 YP_002270553.1 CDS ECH74115_2169 NC_011353.1 2082168 2082749 R identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I complement(2082168..2082749) Escherichia coli O157:H7 str. EC4115 6966768 YP_002270554.1 CDS ECH74115_2170 NC_011353.1 2082746 2083489 R identified by match to protein family HMM PF00877; tail assembly protein complement(2082746..2083489) Escherichia coli O157:H7 str. EC4115 6969136 YP_002270555.1 CDS ECH74115_2171 NC_011353.1 2083500 2084198 R identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L complement(2083500..2084198) Escherichia coli O157:H7 str. EC4115 6971325 YP_002270556.1 CDS ECH74115_2172 NC_011353.1 2084198 2084539 R identified by match to protein family HMM PF05939; phage minor tail protein complement(2084198..2084539) Escherichia coli O157:H7 str. EC4115 6967801 YP_002270557.1 CDS ECH74115_2173 NC_011353.1 2084532 2087774 R identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein complement(2084532..2087774) Escherichia coli O157:H7 str. EC4115 6970006 YP_002270558.1 CDS ECH74115_2174 NC_011353.1 2087826 2088029 R identified by glimmer; hypothetical protein complement(2087826..2088029) Escherichia coli O157:H7 str. EC4115 6968156 YP_002270559.1 CDS ECH74115_2175 NC_011353.1 2088131 2088505 R identified by match to protein family HMM PF06222; phage tail assembly chaperone complement(2088131..2088505) Escherichia coli O157:H7 str. EC4115 6969321 YP_002270560.1 CDS ECH74115_2176 NC_011353.1 2088511 2089227 R identified by match to protein family HMM PF07679; major tail protein complement(2088511..2089227) Escherichia coli O157:H7 str. EC4115 6968536 YP_002270561.1 CDS ECH74115_2177 NC_011353.1 2089286 2089630 R identified by glimmer; hypothetical protein complement(2089286..2089630) Escherichia coli O157:H7 str. EC4115 6966692 YP_002270562.1 CDS ECH74115_2178 NC_011353.1 2089627 2090073 R identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family complement(2089627..2090073) Escherichia coli O157:H7 str. EC4115 6971785 YP_002270563.1 CDS ECH74115_2179 NC_011353.1 2090070 2090420 R identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor complement(2090070..2090420) Escherichia coli O157:H7 str. EC4115 6970306 YP_002270564.1 CDS ECH74115_2180 NC_011353.1 2090430 2090756 R hypothetical protein complement(2090430..2090756) Escherichia coli O157:H7 str. EC4115 6969686 YP_002270565.1 CDS ECH74115_2183 NC_011353.1 2092797 2093018 R hypothetical protein complement(2092797..2093018) Escherichia coli O157:H7 str. EC4115 6967807 YP_002270566.1 CDS ECH74115_2184 NC_011353.1 2093063 2093596 R peptidase U35, phage prohead HK97 complement(2093063..2093596) Escherichia coli O157:H7 str. EC4115 6967192 YP_002270567.1 CDS ECH74115_2185 NC_011353.1 2093562 2093969 R identified by match to protein family HMM PF07041; hypothetical protein complement(2093562..2093969) Escherichia coli O157:H7 str. EC4115 6968292 YP_002270568.1 CDS ECH74115_2186 NC_011353.1 2093974 2094180 R identified by match to protein family HMM PF04971; hypothetical protein complement(2093974..2094180) Escherichia coli O157:H7 str. EC4115 6967574 YP_002270569.1 CDS ECH74115_2187 NC_011353.1 2094188 2094349 D hypothetical protein 2094188..2094349 Escherichia coli O157:H7 str. EC4115 6972124 YP_002270570.1 CDS ECH74115_2188 NC_011353.1 2094628 2096478 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(2094628..2096478) Escherichia coli O157:H7 str. EC4115 6971236 YP_002270571.1 CDS ECH74115_2190 NC_011353.1 2096792 2096959 R hypothetical protein complement(2096792..2096959) Escherichia coli O157:H7 str. EC4115 6969967 YP_002270572.1 CDS ECH74115_2191 NC_011353.1 2096956 2097387 R protein TerB complement(2096956..2097387) Escherichia coli O157:H7 str. EC4115 6968770 YP_002270573.1 CDS ECH74115_2194 NC_011353.1 2097838 2098425 R identified by match to protein family HMM PF00165; transcriptional regulator complement(2097838..2098425) Escherichia coli O157:H7 str. EC4115 6972386 YP_002270574.1 CDS ECH74115_2195 NC_011353.1 2098442 2098582 D identified by glimmer; hypothetical protein 2098442..2098582 Escherichia coli O157:H7 str. EC4115 6967535 YP_002270575.1 CDS ECH74115_2196 NC_011353.1 2098687 2099007 R hypothetical protein complement(2098687..2099007) Escherichia coli O157:H7 str. EC4115 6966813 YP_002270576.1 CDS ECH74115_2197 NC_011353.1 2099109 2099663 R identified by match to protein family HMM PF06576; anti-terminator protein complement(2099109..2099663) Escherichia coli O157:H7 str. EC4115 6966880 YP_002270577.1 CDS ECH74115_2199 NC_011353.1 2100044 2101093 R identified by match to protein family HMM PF06914; hypothetical protein complement(2100044..2101093) Escherichia coli O157:H7 str. EC4115 6968130 YP_002270578.1 CDS ECH74115_2200 NC_011353.1 2101095 2101367 R hypothetical protein complement(2101095..2101367) Escherichia coli O157:H7 str. EC4115 6968689 YP_002270579.1 CDS ECH74115_2201 NC_011353.1 2101489 2101833 R identified by match to protein family HMM PF01336; match to protein family HMM PF04076; protein YgiW complement(2101489..2101833) Escherichia coli O157:H7 str. EC4115 6970103 YP_002270580.1 CDS ECH74115_2202 NC_011353.1 2102399 2102956 R identified by match to protein family HMM PF04448; hypothetical protein complement(2102399..2102956) Escherichia coli O157:H7 str. EC4115 6970518 YP_002270581.1 CDS ECH74115_2203 NC_011353.1 2102958 2103176 R hypothetical protein complement(2102958..2103176) Escherichia coli O157:H7 str. EC4115 6971624 YP_002270582.1 CDS ECH74115_2204 NC_011353.1 2103304 2103615 R hypothetical protein complement(2103304..2103615) Escherichia coli O157:H7 str. EC4115 6972086 YP_002270583.1 CDS ECH74115_2205 NC_011353.1 2103608 2103835 R hypothetical protein complement(2103608..2103835) Escherichia coli O157:H7 str. EC4115 6967443 YP_002270584.1 CDS ECH74115_2206 NC_011353.1 2103832 2104086 R hypothetical protein complement(2103832..2104086) Escherichia coli O157:H7 str. EC4115 6968014 YP_002270585.1 CDS ECH74115_2207 NC_011353.1 2104146 2104862 R identified by match to protein family HMM PF07789; hypothetical protein complement(2104146..2104862) Escherichia coli O157:H7 str. EC4115 6966572 YP_002270586.1 CDS ECH74115_2208 NC_011353.1 2104896 2105357 R hypothetical protein complement(2104896..2105357) Escherichia coli O157:H7 str. EC4115 6967340 YP_002270587.1 CDS ECH74115_2209 NC_011353.1 2105350 2106393 R hypothetical protein complement(2105350..2106393) Escherichia coli O157:H7 str. EC4115 6969174 YP_002270588.1 CDS ECH74115_2210 NC_011353.1 2106462 2106860 R identified by match to protein family HMM PF06254; hypothetical protein complement(2106462..2106860) Escherichia coli O157:H7 str. EC4115 6969909 YP_002270589.1 CDS ECH74115_2211 NC_011353.1 2107205 2107843 D identified by match to protein family HMM PF00717; repressor protein encoded within prophage CP-933O 2107205..2107843 Escherichia coli O157:H7 str. EC4115 6970538 YP_002270590.1 CDS ECH74115_2212 NC_011353.1 2108055 2108288 D identified by match to protein family HMM PF07151; hypothetical protein 2108055..2108288 Escherichia coli O157:H7 str. EC4115 6971456 YP_002270591.1 CDS ECH74115_2213 NC_011353.1 2108300 2108938 D identified by glimmer; hypothetical protein 2108300..2108938 Escherichia coli O157:H7 str. EC4115 6972152 YP_002270592.1 CDS ECH74115_2214 NC_011353.1 2108939 2109148 R identified by glimmer; hypothetical protein complement(2108939..2109148) Escherichia coli O157:H7 str. EC4115 6966564 YP_002270593.1 CDS ECH74115_2215 NC_011353.1 2109447 2109602 R identified by glimmer; hypothetical protein complement(2109447..2109602) Escherichia coli O157:H7 str. EC4115 6967558 YP_002270594.1 CDS ECH74115_2217 NC_011353.1 2109713 2109901 D hypothetical protein 2109713..2109901 Escherichia coli O157:H7 str. EC4115 6970867 YP_002270595.1 CDS ECH74115_2218 NC_011353.1 2109898 2110086 D identified by match to protein family HMM PF07358; hypothetical protein 2109898..2110086 Escherichia coli O157:H7 str. EC4115 6967196 YP_002270596.1 CDS ECH74115_2221 NC_011353.1 2112165 2112371 D identified by match to protein family HMM PF06183; hypothetical protein 2112165..2112371 Escherichia coli O157:H7 str. EC4115 6968987 YP_002270597.1 CDS ECH74115_2222 NC_011353.1 2112421 2113290 R identified by match to protein family HMM PF00872; mutator family transposase complement(2112421..2113290) Escherichia coli O157:H7 str. EC4115 6969621 YP_002270598.1 CDS ECH74115_2223 NC_011353.1 2113711 2114058 D identified by match to protein family HMM PF05717; IS66 family element, orf2 2113711..2114058 Escherichia coli O157:H7 str. EC4115 6970345 YP_002270599.1 CDS ECH74115_2224 NC_011353.1 2114108 2115646 D identified by match to protein family HMM PF03050; IS66 family element, transposase 2114108..2115646 Escherichia coli O157:H7 str. EC4115 6970911 YP_002270600.1 CDS ECH74115_2225 NC_011353.1 2115657 2116079 R transposase complement(2115657..2116079) Escherichia coli O157:H7 str. EC4115 6971529 YP_002270601.1 CDS ECH74115_2226 NC_011353.1 2116229 2116879 R identified by match to protein family HMM PF06416; hypothetical protein complement(2116229..2116879) Escherichia coli O157:H7 str. EC4115 6967882 YP_002270602.1 CDS ECH74115_2227 NC_011353.1 2117153 2117299 R hypothetical protein complement(2117153..2117299) Escherichia coli O157:H7 str. EC4115 6970377 YP_002270603.1 CDS ECH74115_2228 NC_011353.1 2117590 2118165 R identified by match to protein family HMM PF06416; non-LEE-encoded effector NleG complement(2117590..2118165) Escherichia coli O157:H7 str. EC4115 6968313 YP_002270604.1 CDS ECH74115_2229 NC_011353.1 2118279 2118548 R identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein complement(2118279..2118548) Escherichia coli O157:H7 str. EC4115 6969199 YP_002270605.1 CDS ECH74115_2230 NC_011353.1 2118550 2119773 R identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein complement(2118550..2119773) Escherichia coli O157:H7 str. EC4115 6967152 YP_002270606.1 CDS ECH74115_2231 NC_011353.1 2119838 2120437 R identified by match to protein family HMM PF06316; Ail/Lom family protein complement(2119838..2120437) Escherichia coli O157:H7 str. EC4115 6970849 YP_002270607.1 CDS ECH74115_2234 NC_011353.1 2124050 2124193 R identified by glimmer; hypothetical protein complement(2124050..2124193) Escherichia coli O157:H7 str. EC4115 6970322 YP_002270608.1 CDS ECH74115_2235 NC_011353.1 2124171 2124608 R identified by match to protein family HMM TIGR01600; minor tail protein complement(2124171..2124608) Escherichia coli O157:H7 str. EC4115 6968280 YP_002270609.1 CDS ECH74115_2236 NC_011353.1 2124608 2124949 R identified by match to protein family HMM PF05939; phage minor tail protein complement(2124608..2124949) Escherichia coli O157:H7 str. EC4115 6969160 YP_002270610.1 CDS ECH74115_2237 NC_011353.1 2124942 2128184 R identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein complement(2124942..2128184) Escherichia coli O157:H7 str. EC4115 6969074 YP_002270611.1 CDS ECH74115_2238 NC_011353.1 2128232 2128435 R identified by glimmer; hypothetical protein complement(2128232..2128435) Escherichia coli O157:H7 str. EC4115 6968473 YP_002270612.1 CDS ECH74115_2239 NC_011353.1 2128537 2128911 R identified by match to protein family HMM PF06222; phage tail assembly chaperone complement(2128537..2128911) Escherichia coli O157:H7 str. EC4115 6969496 YP_002270613.1 CDS ECH74115_2241 NC_011353.1 2129708 2130052 R identified by glimmer; hypothetical protein complement(2129708..2130052) Escherichia coli O157:H7 str. EC4115 6971452 YP_002270614.1 CDS ECH74115_2242 NC_011353.1 2130049 2130495 R identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family complement(2130049..2130495) Escherichia coli O157:H7 str. EC4115 6967245 YP_002270615.1 CDS ECH74115_2243 NC_011353.1 2130492 2130842 R identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor complement(2130492..2130842) Escherichia coli O157:H7 str. EC4115 6967037 YP_002270616.1 CDS ECH74115_2244 NC_011353.1 2130852 2131178 R hypothetical protein complement(2130852..2131178) Escherichia coli O157:H7 str. EC4115 6969251 YP_002270617.1 CDS ECH74115_2245 NC_011353.1 2131181 2133760 R identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family complement(2131181..2133760) Escherichia coli O157:H7 str. EC4115 6970353 YP_002270618.1 CDS ECH74115_2246 NC_011353.1 2133972 2135909 R identified by match to protein family HMM PF04586; prohead protease complement(2133972..2135909) Escherichia coli O157:H7 str. EC4115 6970471 YP_002270619.1 CDS ECH74115_2247 NC_011353.1 2135973 2137634 R identified by match to protein family HMM PF03354; phage terminase, large subunit complement(2135973..2137634) Escherichia coli O157:H7 str. EC4115 6968541 YP_002270620.1 CDS ECH74115_2248 NC_011353.1 2137631 2138194 R terminase small subunit complement(2137631..2138194) Escherichia coli O157:H7 str. EC4115 6969374 YP_002270621.1 CDS ECH74115_2249 NC_011353.1 2138486 2138851 R identified by match to protein family HMM PF01844; HNH endonuclease complement(2138486..2138851) Escherichia coli O157:H7 str. EC4115 6969543 YP_002270622.1 CDS ECH74115_2250 NC_011353.1 2138953 2139120 D hypothetical protein 2138953..2139120 Escherichia coli O157:H7 str. EC4115 6971444 YP_002270623.1 CDS ECH74115_2251 NC_011353.1 2139483 2139950 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(2139483..2139950) Escherichia coli O157:H7 str. EC4115 6971101 YP_002270624.1 CDS ECH74115_2252 NC_011353.1 2139988 2140104 R hypothetical protein complement(2139988..2140104) Escherichia coli O157:H7 str. EC4115 6971598 YP_002270625.1 CDS ECH74115_2253 NC_011353.1 2140104 2140673 R anti-repressor protein Ant complement(2140104..2140673) Escherichia coli O157:H7 str. EC4115 6967397 YP_002270626.1 CDS ECH74115_2254 NC_011353.1 2140944 2141477 R identified by match to protein family HMM PF00959; phage lysozyme complement(2140944..2141477) Escherichia coli O157:H7 str. EC4115 6968111 YP_002270627.1 CDS ECH74115_2255 NC_011353.1 2141528 2141872 R identified by match to protein family HMM PF07041; hypothetical protein complement(2141528..2141872) Escherichia coli O157:H7 str. EC4115 6969109 YP_002270628.1 CDS ECH74115_2256 NC_011353.1 2141877 2142083 R identified by match to protein family HMM PF04971; hypothetical protein complement(2141877..2142083) Escherichia coli O157:H7 str. EC4115 6970077 YP_002270629.1 CDS ECH74115_2258 NC_011353.1 2142532 2144382 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(2142532..2144382) Escherichia coli O157:H7 str. EC4115 6967239 YP_002270630.1 CDS ECH74115_2260 NC_011353.1 2144697 2144864 R hypothetical protein complement(2144697..2144864) Escherichia coli O157:H7 str. EC4115 6971570 YP_002270631.1 CDS ECH74115_2265 NC_011353.1 2145774 2145896 R identified by glimmer; hypothetical protein complement(2145774..2145896) Escherichia coli O157:H7 str. EC4115 6972427 YP_002270632.1 CDS ECH74115_2266 NC_011353.1 2145927 2146616 R identified by match to protein family HMM PF06323; antitermination protein Q complement(2145927..2146616) Escherichia coli O157:H7 str. EC4115 6967538 YP_002270633.1 CDS ECH74115_2267 NC_011353.1 2146613 2146972 R identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease complement(2146613..2146972) Escherichia coli O157:H7 str. EC4115 6968312 YP_002270634.1 CDS ECH74115_2268 NC_011353.1 2146985 2148034 R identified by match to protein family HMM PF06914; hypothetical protein complement(2146985..2148034) Escherichia coli O157:H7 str. EC4115 6971247 YP_002270635.1 CDS ECH74115_2270 NC_011353.1 2148883 2149032 R hypothetical protein complement(2148883..2149032) Escherichia coli O157:H7 str. EC4115 6969520 YP_002270636.1 CDS ECH74115_2271 NC_011353.1 2149103 2149687 R identified by match to protein family HMM PF04448; hypothetical protein complement(2149103..2149687) Escherichia coli O157:H7 str. EC4115 6970761 YP_002270637.1 CDS ECH74115_2272 NC_011353.1 2149744 2150139 R identified by match to protein family HMM PF06163; hypothetical protein complement(2149744..2150139) Escherichia coli O157:H7 str. EC4115 6967696 YP_002270638.1 CDS ECH74115_2275 NC_011353.1 2150950 2151690 R identified by match to protein family HMM PF01695; replication protein complement(2150950..2151690) Escherichia coli O157:H7 str. EC4115 6971717 YP_002270639.1 CDS ECH74115_2276 NC_011353.1 2151697 2152584 R phage O protein complement(2151697..2152584) Escherichia coli O157:H7 str. EC4115 6970342 YP_002270640.1 CDS ECH74115_2277 NC_011353.1 2152682 2153107 R identified by match to protein family HMM PF06254; hypothetical protein complement(2152682..2153107) Escherichia coli O157:H7 str. EC4115 6970958 YP_002270641.1 CDS ECH74115_2278 NC_011353.1 2153657 2153875 D hypothetical protein 2153657..2153875 Escherichia coli O157:H7 str. EC4115 6968715 YP_002270642.1 CDS ECH74115_2279 NC_011353.1 2153860 2154087 D hypothetical protein 2153860..2154087 Escherichia coli O157:H7 str. EC4115 6969452 YP_002270643.1 CDS ECH74115_2280 NC_011353.1 2155091 2155309 D identified by glimmer; hypothetical protein 2155091..2155309 Escherichia coli O157:H7 str. EC4115 6969728 YP_002270644.1 CDS ECH74115_2281 NC_011353.1 2155679 2155849 R hypothetical protein complement(2155679..2155849) Escherichia coli O157:H7 str. EC4115 6969823 YP_002270645.1 CDS dicB NC_011353.1 2155878 2156066 D identified by match to protein family HMM PF05358; division inhibition protein DicB 2155878..2156066 Escherichia coli O157:H7 str. EC4115 6968977 YP_002270646.1 CDS ECH74115_2283 NC_011353.1 2156063 2156254 D identified by match to protein family HMM PF07358; hypothetical protein 2156063..2156254 Escherichia coli O157:H7 str. EC4115 6968172 YP_002270647.1 CDS ECH74115_2284 NC_011353.1 2156347 2157477 D exonuclease family protein 2156347..2157477 Escherichia coli O157:H7 str. EC4115 6967424 YP_002270648.1 CDS ECH74115_2285 NC_011353.1 2157483 2157809 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2157483..2157809 Escherichia coli O157:H7 str. EC4115 6966632 YP_002270649.1 CDS ECH74115_2286 NC_011353.1 2157806 2158696 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2157806..2158696 Escherichia coli O157:H7 str. EC4115 6971430 YP_002270650.1 CDS ECH74115_2287 NC_011353.1 2158749 2160131 D identified by match to protein family HMM PF00929; exonuclease family protein 2158749..2160131 Escherichia coli O157:H7 str. EC4115 6970575 YP_002270651.1 CDS ECH74115_2288 NC_011353.1 2160219 2160455 D identified by match to protein family HMM PF06806; phage excisionase 2160219..2160455 Escherichia coli O157:H7 str. EC4115 6968991 YP_002270652.1 CDS ECH74115_2290 NC_011353.1 2160975 2161181 D transposase 2160975..2161181 Escherichia coli O157:H7 str. EC4115 6971066 YP_002270653.1 CDS ECH74115_2291 NC_011353.1 2161444 2161770 R identified by match to protein family HMM PF02694; hypothetical protein complement(2161444..2161770) Escherichia coli O157:H7 str. EC4115 6971821 YP_002270654.1 CDS ECH74115_2292 NC_011353.1 2161905 2162246 D identified by match to protein family HMM PF06932; hypothetical protein 2161905..2162246 Escherichia coli O157:H7 str. EC4115 6968199 YP_002270655.1 CDS speG NC_011353.1 2162281 2162841 D identified by match to protein family HMM PF00583; diamine N-acetyltransferase 2162281..2162841 Escherichia coli O157:H7 str. EC4115 6969030 YP_002270656.1 CDS ECH74115_2294 NC_011353.1 2162844 2163590 R identified by match to protein family HMM PF06788; hypothetical protein complement(2162844..2163590) Escherichia coli O157:H7 str. EC4115 6969969 YP_002270657.1 CDS ECH74115_2295 NC_011353.1 2163662 2163967 D identified by match to protein family HMM PF06649; hypothetical protein 2163662..2163967 Escherichia coli O157:H7 str. EC4115 6970631 YP_002270658.1 CDS ynfE NC_011353.1 2164166 2166592 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase, A subunit YnfE 2164166..2166592 Escherichia coli O157:H7 str. EC4115 6971676 YP_002270659.1 CDS ECH74115_2297 NC_011353.1 2166680 2169076 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 2166680..2169076 Escherichia coli O157:H7 str. EC4115 6972219 YP_002270660.1 CDS dmsB_2 NC_011353.1 2169087 2169704 D identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951; anaerobic dimethylsulfoxide reductase subunit B 2169087..2169704 Escherichia coli O157:H7 str. EC4115 6967519 YP_002270661.1 CDS dmsC2 NC_011353.1 2169706 2170560 D identified by match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 2169706..2170560 Escherichia coli O157:H7 str. EC4115 6970973 YP_002270662.1 CDS dmsD NC_011353.1 2170603 2171217 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 2170603..2171217 Escherichia coli O157:H7 str. EC4115 6972141 YP_002270663.1 CDS ECH74115_2301 NC_011353.1 2171231 2171344 D identified by glimmer; hypothetical protein 2171231..2171344 Escherichia coli O157:H7 str. EC4115 6971679 YP_002270664.1 CDS ECH74115_2303 NC_011353.1 2171411 2172667 D identified by match to protein family HMM PF00654; voltage-gated ClC-type chloride channel ClcB 2171411..2172667 Escherichia coli O157:H7 str. EC4115 6967335 YP_002270665.1 CDS bioD2 NC_011353.1 2172620 2173315 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(2172620..2173315) Escherichia coli O157:H7 str. EC4115 6968921 YP_002270666.1 CDS mic NC_011353.1 2173440 2174660 R identified by match to protein family HMM PF00480; transcriptional regulator Mic complement(2173440..2174660) Escherichia coli O157:H7 str. EC4115 6966550 YP_002270667.1 CDS ECH74115_2305 NC_011353.1 2174795 2175688 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2174795..2175688) Escherichia coli O157:H7 str. EC4115 6968465 YP_002270668.1 CDS ynfM NC_011353.1 2175795 2177048 D identified by match to protein family HMM PF07690; major facilitator family transporter 2175795..2177048 Escherichia coli O157:H7 str. EC4115 6971513 YP_002270669.1 CDS ECH74115_2307 NC_011353.1 2177445 2177780 D required for growth and survival under moderately acid conditions; acid shock protein 2177445..2177780 Escherichia coli O157:H7 str. EC4115 6970728 YP_002270670.1 CDS ECH74115_2308 NC_011353.1 2178056 2178877 D identified by match to protein family HMM PF00089; peptidase, S1A (chymotrypsin) family 2178056..2178877 Escherichia coli O157:H7 str. EC4115 6967098 YP_002270671.1 CDS mdtI NC_011353.1 2178916 2179245 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(2178916..2179245) Escherichia coli O157:H7 str. EC4115 6966660 YP_002270672.1 CDS mdtJ NC_011353.1 2179232 2179597 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(2179232..2179597) Escherichia coli O157:H7 str. EC4115 6971670 YP_002270673.1 CDS tqsA NC_011353.1 2180009 2181043 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 2180009..2181043 Escherichia coli O157:H7 str. EC4115 6969981 YP_002270674.1 CDS pntB NC_011353.1 2181068 2182456 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(2181068..2182456) Escherichia coli O157:H7 str. EC4115 6967127 YP_002270675.1 CDS pntA NC_011353.1 2182467 2184053 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(2182467..2184053) Escherichia coli O157:H7 str. EC4115 6967874 YP_002270676.1 CDS ydgH NC_011353.1 2184523 2185467 D identified by match to protein family HMM PF07338; YdgH protein 2184523..2185467 Escherichia coli O157:H7 str. EC4115 6968370 YP_002270677.1 CDS arcD NC_011353.1 2185653 2187035 D identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905; arginine/ornithine antiporter 2185653..2187035 Escherichia coli O157:H7 str. EC4115 6966765 YP_002270678.1 CDS ECH74115_2317 NC_011353.1 2187072 2187794 D identified by match to protein family HMM PF00106; short chain dehydrogenase 2187072..2187794 Escherichia coli O157:H7 str. EC4115 6969678 YP_002270679.1 CDS ECH74115_2316 NC_011353.1 2187791 2188126 R identified by match to protein family HMM PF06942; hypothetical protein complement(2187791..2188126) Escherichia coli O157:H7 str. EC4115 6970939 YP_002270680.1 CDS rstA NC_011353.1 2188255 2188974 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 2188255..2188974 Escherichia coli O157:H7 str. EC4115 6970153 YP_002270681.1 CDS rstB NC_011353.1 2188978 2190279 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein RstB 2188978..2190279 Escherichia coli O157:H7 str. EC4115 6972113 YP_002270682.1 CDS tus NC_011353.1 2190343 2191284 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 2190343..2191284 Escherichia coli O157:H7 str. EC4115 6968038 YP_002270683.1 CDS fumC NC_011353.1 2191281 2192684 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(2191281..2192684) Escherichia coli O157:H7 str. EC4115 6970722 YP_002270684.1 CDS fumA NC_011353.1 2192827 2194473 R identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase complement(2192827..2194473) Escherichia coli O157:H7 str. EC4115 6967568 YP_002270685.1 CDS manA NC_011353.1 2194672 2195847 D identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 2194672..2195847 Escherichia coli O157:H7 str. EC4115 6968834 YP_002270686.1 CDS ECH74115_2324 NC_011353.1 2195948 2197456 D identified by match to protein family HMM PF06097; hypothetical protein 2195948..2197456 Escherichia coli O157:H7 str. EC4115 6971978 YP_002270687.1 CDS uidB NC_011353.1 2198804 2200177 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792; glucuronide transporter complement(2198804..2200177) Escherichia coli O157:H7 str. EC4115 6971317 YP_002270688.1 CDS uidR NC_011353.1 2202378 2202965 R identified by match to protein family HMM PF00440; transcriptional regulator UidR complement(2202378..2202965) Escherichia coli O157:H7 str. EC4115 6967575 YP_002270689.1 CDS ECH74115_2331 NC_011353.1 2203197 2203964 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(2203197..2203964) Escherichia coli O157:H7 str. EC4115 6966614 YP_002270690.1 CDS malI NC_011353.1 2204076 2205104 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(2204076..2205104) Escherichia coli O157:H7 str. EC4115 6970553 YP_002270691.1 CDS malX NC_011353.1 2205279 2206871 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; PTS system maltose and glucose-specific transporter subunits IICB 2205279..2206871 Escherichia coli O157:H7 str. EC4115 6968923 YP_002270692.1 CDS malY NC_011353.1 2206881 2208053 D identified by match to protein family HMM PF00155; MalY protein 2206881..2208053 Escherichia coli O157:H7 str. EC4115 6972202 YP_002270693.1 CDS add NC_011353.1 2208157 2209158 D catalyzes the formation of inosine from adenosine; adenosine deaminase 2208157..2209158 Escherichia coli O157:H7 str. EC4115 6971220 YP_002270694.1 CDS ECH74115_2336 NC_011353.1 2209194 2210234 R identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase complement(2209194..2210234) Escherichia coli O157:H7 str. EC4115 6966707 YP_002270695.1 CDS ECH74115_2337 NC_011353.1 2210875 2211090 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 2210875..2211090 Escherichia coli O157:H7 str. EC4115 6972149 YP_002270696.1 CDS ECH74115_2338 NC_011353.1 2211176 2211616 D hypothetical protein 2211176..2211616 Escherichia coli O157:H7 str. EC4115 6968226 YP_002270697.1 CDS rnfA NC_011353.1 2211693 2212274 D identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943; Na(+)-translocating NADH-quinone reductase subunit E 2211693..2212274 Escherichia coli O157:H7 str. EC4115 6967249 YP_002270698.1 CDS rnfB NC_011353.1 2212274 2212852 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 2212274..2212852 Escherichia coli O157:H7 str. EC4115 6968670 YP_002270699.1 CDS ECH74115_2341 NC_011353.1 2212845 2215163 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 2212845..2215163 Escherichia coli O157:H7 str. EC4115 6968567 YP_002270700.1 CDS rnfD NC_011353.1 2215164 2216222 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 2215164..2216222 Escherichia coli O157:H7 str. EC4115 6970782 YP_002270701.1 CDS rnfG NC_011353.1 2216226 2216846 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 2216226..2216846 Escherichia coli O157:H7 str. EC4115 6969830 YP_002270702.1 CDS rnfE NC_011353.1 2216850 2217545 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 2216850..2217545 Escherichia coli O157:H7 str. EC4115 6972053 YP_002270703.1 CDS nth NC_011353.1 2217545 2218180 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 2217545..2218180 Escherichia coli O157:H7 str. EC4115 6967516 YP_002270704.1 CDS tppB NC_011353.1 2218791 2220293 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 2218791..2220293 Escherichia coli O157:H7 str. EC4115 6966884 YP_002270705.1 CDS gst NC_011353.1 2220399 2221004 D identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathionine S-transferase 2220399..2221004 Escherichia coli O157:H7 str. EC4115 6968674 YP_002270706.1 CDS pdxY NC_011353.1 2221048 2221908 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(2221048..2221908) Escherichia coli O157:H7 str. EC4115 6968121 YP_002270707.1 CDS tyrS NC_011353.1 2221970 2223244 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(2221970..2223244) Escherichia coli O157:H7 str. EC4115 6970718 YP_002270708.1 CDS pdxH NC_011353.1 2223373 2224029 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(2223373..2224029) Escherichia coli O157:H7 str. EC4115 6970050 YP_002270709.1 CDS ECH74115_2351 NC_011353.1 2224088 2224411 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(2224088..2224411) Escherichia coli O157:H7 str. EC4115 6969075 YP_002270710.1 CDS anmK NC_011353.1 2224515 2225624 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(2224515..2225624) Escherichia coli O157:H7 str. EC4115 6968418 YP_002270711.1 CDS slyB NC_011353.1 2225897 2226364 D identified by match to protein family HMM PF05433; outer membrane lipoprotein SlyB 2225897..2226364 Escherichia coli O157:H7 str. EC4115 6968282 YP_002270712.1 CDS ECH74115_2354 NC_011353.1 2226411 2226845 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(2226411..2226845) Escherichia coli O157:H7 str. EC4115 6967309 YP_002270713.1 CDS ECH74115_2355 NC_011353.1 2227046 2227282 D identified by match to protein family HMM PF07869; hypothetical protein 2227046..2227282 Escherichia coli O157:H7 str. EC4115 6966666 YP_002270714.1 CDS ECH74115_2356 NC_011353.1 2227285 2228142 D identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family 2227285..2228142 Escherichia coli O157:H7 str. EC4115 6972126 YP_002270715.1 CDS ECH74115_2357 NC_011353.1 2228163 2230154 D identified by match to protein family HMM PF04632; fusaric acid resistance domain-containing protein 2228163..2230154 Escherichia coli O157:H7 str. EC4115 6971504 YP_002270716.1 CDS sodC NC_011353.1 2230155 2230676 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(2230155..2230676) Escherichia coli O157:H7 str. EC4115 6970487 YP_002270717.1 CDS ECH74115_2360 NC_011353.1 2231713 2231832 D identified by glimmer; hypothetical protein 2231713..2231832 Escherichia coli O157:H7 str. EC4115 6970681 YP_002270718.1 CDS ECH74115_2361 NC_011353.1 2232044 2232643 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2232044..2232643 Escherichia coli O157:H7 str. EC4115 6970019 YP_002270719.1 CDS nemA NC_011353.1 2232680 2233777 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 2232680..2233777 Escherichia coli O157:H7 str. EC4115 6966696 YP_002270720.1 CDS gloA NC_011353.1 2233858 2234265 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 2233858..2234265 Escherichia coli O157:H7 str. EC4115 6969246 YP_002270721.1 CDS rnt NC_011353.1 2234368 2235015 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2234368..2235015 Escherichia coli O157:H7 str. EC4115 6970999 YP_002270722.1 CDS lhr NC_011353.1 2235108 2239724 D similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; ATP-dependent helicase Lhr 2235108..2239724 Escherichia coli O157:H7 str. EC4115 6967289 YP_002270723.1 CDS ECH74115_2366 NC_011353.1 2239775 2240122 R identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; hypothetical protein complement(2239775..2240122) Escherichia coli O157:H7 str. EC4115 6969902 YP_002270724.1 CDS ECH74115_2367 NC_011353.1 2240457 2241272 D identified by match to protein family HMM PF00877; NlpC/P60 family protein 2240457..2241272 Escherichia coli O157:H7 str. EC4115 6969647 YP_002270725.1 CDS sodB NC_011353.1 2241400 2241981 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 2241400..2241981 Escherichia coli O157:H7 str. EC4115 6968613 YP_002270726.1 CDS ECH74115_2369 NC_011353.1 2242127 2243296 R identified by match to protein family HMM PF07690; major facilitator family transporter complement(2242127..2243296) Escherichia coli O157:H7 str. EC4115 6970544 YP_002270727.1 CDS ECH74115_2370 NC_011353.1 2243462 2243581 R identified by glimmer; membrane protein complement(2243462..2243581) Escherichia coli O157:H7 str. EC4115 6967968 YP_002270728.1 CDS purR NC_011353.1 2243850 2244875 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 2243850..2244875 Escherichia coli O157:H7 str. EC4115 6970030 YP_002270729.1 CDS ECH74115_2371 NC_011353.1 2244872 2245804 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(2244872..2245804) Escherichia coli O157:H7 str. EC4115 6971291 YP_002270730.1 CDS ECH74115_2373 NC_011353.1 2245917 2247128 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2245917..2247128 Escherichia coli O157:H7 str. EC4115 6970686 YP_002270731.1 CDS cfa NC_011353.1 2247419 2248567 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 2247419..2248567 Escherichia coli O157:H7 str. EC4115 6971935 YP_002270732.1 CDS ribE NC_011353.1 2248607 2249248 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(2248607..2249248) Escherichia coli O157:H7 str. EC4115 6966866 YP_002270733.1 CDS ECH74115_2376 NC_011353.1 2249463 2250836 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 2249463..2250836 Escherichia coli O157:H7 str. EC4115 6967543 YP_002270734.1 CDS ECH74115_2377 NC_011353.1 2250877 2252133 R hypothetical protein complement(2250877..2252133) Escherichia coli O157:H7 str. EC4115 6968002 YP_002270735.1 CDS ydhR NC_011353.1 2252706 2253011 D identified by match to protein family HMM PF08803; hypothetical protein 2252706..2253011 Escherichia coli O157:H7 str. EC4115 6972367 YP_002270736.1 CDS ECH74115_2381 NC_011353.1 2253137 2254741 D hypothetical protein 2253137..2254741 Escherichia coli O157:H7 str. EC4115 6970786 YP_002270737.1 CDS ECH74115_2382 NC_011353.1 2254753 2255565 R hypothetical protein complement(2254753..2255565) Escherichia coli O157:H7 str. EC4115 6971708 YP_002270738.1 CDS ECH74115_2383 NC_011353.1 2255569 2256354 R identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit complement(2255569..2256354) Escherichia coli O157:H7 str. EC4115 6970664 YP_002270739.1 CDS ECH74115_2384 NC_011353.1 2256351 2257070 R identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein complement(2256351..2257070) Escherichia coli O157:H7 str. EC4115 6970113 YP_002270740.1 CDS ECH74115_2385 NC_011353.1 2257083 2257721 R hypothetical protein complement(2257083..2257721) Escherichia coli O157:H7 str. EC4115 6967529 YP_002270741.1 CDS ECH74115_2386 NC_011353.1 2257734 2259836 R identified by match to protein family HMM PF01314; match to protein family HMM PF02730; oxidoreductase complement(2257734..2259836) Escherichia coli O157:H7 str. EC4115 6966552 YP_002270742.1 CDS ECH74115_2387 NC_011353.1 2259857 2260483 R identified by match to protein family HMM PF00037; hypothetical protein complement(2259857..2260483) Escherichia coli O157:H7 str. EC4115 6971948 YP_002270743.1 CDS ECH74115_2388 NC_011353.1 2260511 2260648 D identified by glimmer; hypothetical protein 2260511..2260648 Escherichia coli O157:H7 str. EC4115 6971342 YP_002270744.1 CDS ECH74115_2389 NC_011353.1 2260939 2261109 R hypothetical protein complement(2260939..2261109) Escherichia coli O157:H7 str. EC4115 6970043 YP_002270745.1 CDS pykF NC_011353.1 2261705 2263117 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2261705..2263117 Escherichia coli O157:H7 str. EC4115 6971952 YP_002270746.1 CDS lpp NC_011353.1 2263428 2263664 D identified by match to protein family HMM PF04728; major outer membrane lipoprotein 2263428..2263664 Escherichia coli O157:H7 str. EC4115 6968748 YP_002270747.1 CDS ECH74115_2392 NC_011353.1 2263727 2264731 R identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM domain/ErfK/YbiS/YcfS/YnhG family protein complement(2263727..2264731) Escherichia coli O157:H7 str. EC4115 6966759 YP_002270748.1 CDS sufE NC_011353.1 2264880 2265296 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(2264880..2265296) Escherichia coli O157:H7 str. EC4115 6970100 YP_002270749.1 CDS sufS NC_011353.1 2265309 2266529 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(2265309..2266529) Escherichia coli O157:H7 str. EC4115 6971908 YP_002270750.1 CDS sufD NC_011353.1 2266526 2267797 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(2266526..2267797) Escherichia coli O157:H7 str. EC4115 6969229 YP_002270751.1 CDS sufC NC_011353.1 2267772 2268518 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(2267772..2268518) Escherichia coli O157:H7 str. EC4115 6968056 YP_002270752.1 CDS sufB NC_011353.1 2268528 2270015 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(2268528..2270015) Escherichia coli O157:H7 str. EC4115 6967257 YP_002270753.1 CDS sufA NC_011353.1 2270024 2270392 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(2270024..2270392) Escherichia coli O157:H7 str. EC4115 6966772 YP_002270754.1 CDS ECH74115_2400 NC_011353.1 2270941 2271129 R hypothetical protein complement(2270941..2271129) Escherichia coli O157:H7 str. EC4115 6972289 YP_002270755.1 CDS ydiL NC_011353.1 2271229 2271639 R identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein complement(2271229..2271639) Escherichia coli O157:H7 str. EC4115 6971299 YP_002270756.1 CDS ECH74115_2402 NC_011353.1 2271636 2274692 R identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding complement(2271636..2274692) Escherichia coli O157:H7 str. EC4115 6970490 YP_002270757.1 CDS ydiK NC_011353.1 2275081 2276193 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 2275081..2276193 Escherichia coli O157:H7 str. EC4115 6967730 YP_002270758.1 CDS ECH74115_2405 NC_011353.1 2276622 2276978 D identified by match to protein family HMM PF08965; hypothetical protein 2276622..2276978 Escherichia coli O157:H7 str. EC4115 6972307 YP_002270759.1 CDS ydiM NC_011353.1 2277138 2278292 D identified by match to protein family HMM PF07690; major facilitator family transporter 2277138..2278292 Escherichia coli O157:H7 str. EC4115 6969218 YP_002270760.1 CDS ECH74115_2407 NC_011353.1 2278519 2279784 D identified by match to protein family HMM PF07690; major facilitator family transporter 2278519..2279784 Escherichia coli O157:H7 str. EC4115 6971454 YP_002270761.1 CDS ECH74115_2408 NC_011353.1 2279796 2280662 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2279796..2280662 Escherichia coli O157:H7 str. EC4115 6972147 YP_002270762.1 CDS aroD NC_011353.1 2280693 2281451 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2280693..2281451 Escherichia coli O157:H7 str. EC4115 6967416 YP_002270763.1 CDS pct NC_011353.1 2281596 2283191 D identified by match to protein family HMM PF01144; propionate CoA-transferase 2281596..2283191 Escherichia coli O157:H7 str. EC4115 6970858 YP_002270764.1 CDS ECH74115_2411 NC_011353.1 2283205 2284356 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 2283205..2284356 Escherichia coli O157:H7 str. EC4115 6968910 YP_002270765.1 CDS ECH74115_2412 NC_011353.1 2284399 2285310 R identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883; AraC family transcriptional regulator complement(2284399..2285310) Escherichia coli O157:H7 str. EC4115 6967068 YP_002270766.1 CDS ECH74115_2413 NC_011353.1 2285413 2285589 R identified by glimmer; hypothetical protein complement(2285413..2285589) Escherichia coli O157:H7 str. EC4115 6970472 YP_002270767.1 CDS ECH74115_2414 NC_011353.1 2285626 2286390 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 2285626..2286390 Escherichia coli O157:H7 str. EC4115 6972199 YP_002270768.1 CDS ECH74115_2415 NC_011353.1 2286410 2287348 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2286410..2287348 Escherichia coli O157:H7 str. EC4115 6969752 YP_002270769.1 CDS ECH74115_2416 NC_011353.1 2287404 2288693 D identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; hypothetical protein 2287404..2288693 Escherichia coli O157:H7 str. EC4115 6970586 YP_002270770.1 CDS ECH74115_2417 NC_011353.1 2288690 2288983 D iron-sulfur cluster-binding protein 2288690..2288983 Escherichia coli O157:H7 str. EC4115 6966908 YP_002270771.1 CDS ppsA NC_011353.1 2290742 2293120 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(2290742..2293120) Escherichia coli O157:H7 str. EC4115 6971859 YP_002270772.1 CDS ECH74115_2420 NC_011353.1 2293174 2293341 R identified by glimmer; hypothetical protein complement(2293174..2293341) Escherichia coli O157:H7 str. EC4115 6966828 YP_002270773.1 CDS ECH74115_2421 NC_011353.1 2293453 2294286 D identified by match to protein family HMM PF03618; hypothetical protein 2293453..2294286 Escherichia coli O157:H7 str. EC4115 6970235 YP_002270774.1 CDS aroH NC_011353.1 2294443 2295489 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2294443..2295489 Escherichia coli O157:H7 str. EC4115 6971417 YP_002270775.1 CDS ECH74115_2423 NC_011353.1 2295594 2295812 D hypothetical protein 2295594..2295812 Escherichia coli O157:H7 str. EC4115 6969349 YP_002270776.1 CDS ECH74115_2424 NC_011353.1 2295816 2297252 R identified by match to protein family HMM PF02696; hypothetical protein complement(2295816..2297252) Escherichia coli O157:H7 str. EC4115 6971799 YP_002270777.1 CDS ECH74115_2425 NC_011353.1 2297315 2298028 R hypothetical protein complement(2297315..2298028) Escherichia coli O157:H7 str. EC4115 6969396 YP_002270778.1 CDS ECH74115_2426 NC_011353.1 2298275 2298739 R identified by match to protein family HMM PF00877; lipoprotein, NlpC/P60 family complement(2298275..2298739) Escherichia coli O157:H7 str. EC4115 6968565 YP_002270779.1 CDS btuD NC_011353.1 2298817 2299566 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(2298817..2299566) Escherichia coli O157:H7 str. EC4115 6966934 YP_002270780.1 CDS btuE NC_011353.1 2299566 2300117 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(2299566..2300117) Escherichia coli O157:H7 str. EC4115 6967752 YP_002270781.1 CDS btuC NC_011353.1 2300180 2301160 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(2300180..2301160) Escherichia coli O157:H7 str. EC4115 6971073 YP_002270782.1 CDS ihfA NC_011353.1 2301261 2301560 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(2301261..2301560) Escherichia coli O157:H7 str. EC4115 6971877 YP_002270783.1 CDS pheT NC_011353.1 2301565 2303952 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2301565..2303952) Escherichia coli O157:H7 str. EC4115 6970197 YP_002270784.1 CDS pheS NC_011353.1 2303967 2304950 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2303967..2304950) Escherichia coli O157:H7 str. EC4115 6971075 YP_002270785.1 CDS ECH74115_2433 NC_011353.1 2305139 2305273 R hypothetical protein complement(2305139..2305273) Escherichia coli O157:H7 str. EC4115 6968623 YP_002270786.1 CDS rplT NC_011353.1 2305400 2305756 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2305400..2305756) Escherichia coli O157:H7 str. EC4115 6970535 YP_002270787.1 CDS rpmI NC_011353.1 2305809 2306006 R identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 complement(2305809..2306006) Escherichia coli O157:H7 str. EC4115 6967937 YP_002270788.1 CDS infC NC_011353.1 2306103 2306537 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(2306103..2306537) Escherichia coli O157:H7 str. EC4115 6968775 YP_002270789.1 CDS thrS NC_011353.1 2306649 2308577 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(2306649..2308577) Escherichia coli O157:H7 str. EC4115 6970857 YP_002270790.1 CDS ECH74115_2438 NC_011353.1 2309100 2310998 D identified by match to protein family HMM PF07906; hypothetical protein 2309100..2310998 Escherichia coli O157:H7 str. EC4115 6971631 YP_002270791.1 CDS ECH74115_2439 NC_011353.1 2311158 2311280 D hypothetical protein 2311158..2311280 Escherichia coli O157:H7 str. EC4115 6969638 YP_002270792.1 CDS ECH74115_2440 NC_011353.1 2311333 2312091 R identified by match to protein family HMM PF04338; hypothetical protein complement(2311333..2312091) Escherichia coli O157:H7 str. EC4115 6970297 YP_002270793.1 CDS pfkB NC_011353.1 2312378 2313307 D identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 6-phosphofructokinase 2312378..2313307 Escherichia coli O157:H7 str. EC4115 6969289 YP_002270794.1 CDS ECH74115_2442 NC_011353.1 2313408 2313698 D hypothetical protein 2313408..2313698 Escherichia coli O157:H7 str. EC4115 6969767 YP_002270795.1 CDS ECH74115_2443 NC_011353.1 2313804 2314664 D identified by match to protein family HMM PF01636; match to protein family HMM PF03881; fructosamine kinase 2313804..2314664 Escherichia coli O157:H7 str. EC4115 6967408 YP_002270796.1 CDS ECH74115_2444 NC_011353.1 2314705 2315241 R hypothetical protein complement(2314705..2315241) Escherichia coli O157:H7 str. EC4115 6968399 YP_002270797.1 CDS ECH74115_2445 NC_011353.1 2315388 2316056 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2315388..2316056 Escherichia coli O157:H7 str. EC4115 6967606 YP_002270798.1 CDS ECH74115_2446 NC_011353.1 2316219 2316809 D identified by match to protein family HMM PF04307; hypothetical protein 2316219..2316809 Escherichia coli O157:H7 str. EC4115 6967161 YP_002270799.1 CDS ECH74115_2447 NC_011353.1 2316942 2318333 D identified by match to protein family HMM PF00375; transporter dicarboxylate/amino acid:cation (Na+ or H+) symporter (DAACS) family 2316942..2318333 Escherichia coli O157:H7 str. EC4115 6971413 YP_002270800.1 CDS cedA NC_011353.1 2319428 2319670 R cell division modulator complement(2319428..2319670) Escherichia coli O157:H7 str. EC4115 6969442 YP_002270801.1 CDS katE NC_011353.1 2319874 2322135 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2319874..2322135 Escherichia coli O157:H7 str. EC4115 6968966 YP_002270802.1 CDS ECH74115_2451 NC_011353.1 2322182 2322940 R identified by match to protein family HMM PF04794; hypothetical protein complement(2322182..2322940) Escherichia coli O157:H7 str. EC4115 6967329 YP_002270803.1 CDS chbF NC_011353.1 2322953 2324305 R identified by match to protein family HMM PF02056; 6-phospho-beta-glucosidase complement(2322953..2324305) Escherichia coli O157:H7 str. EC4115 6967773 YP_002270804.1 CDS chbR NC_011353.1 2324410 2325249 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(2324410..2325249) Escherichia coli O157:H7 str. EC4115 6966962 YP_002270805.1 CDS chbA NC_011353.1 2325260 2325607 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(2325260..2325607) Escherichia coli O157:H7 str. EC4115 6966994 YP_002270806.1 CDS chbC NC_011353.1 2325661 2327019 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(2325661..2327019) Escherichia coli O157:H7 str. EC4115 6969569 YP_002270807.1 CDS chbB NC_011353.1 2327104 2327424 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(2327104..2327424) Escherichia coli O157:H7 str. EC4115 6971605 YP_002270808.1 CDS osmE NC_011353.1 2327724 2328062 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(2327724..2328062) Escherichia coli O157:H7 str. EC4115 6969276 YP_002270809.1 CDS nadE NC_011353.1 2328264 2329091 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2328264..2329091 Escherichia coli O157:H7 str. EC4115 6968516 YP_002270810.1 CDS cho NC_011353.1 2329321 2330208 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2329321..2330208 Escherichia coli O157:H7 str. EC4115 6967670 YP_002270811.1 CDS ECH74115_2459 NC_011353.1 2330168 2330743 R identified by match to protein family HMM PF05962; hypothetical protein complement(2330168..2330743) Escherichia coli O157:H7 str. EC4115 6971345 YP_002270812.1 CDS spy NC_011353.1 2330946 2331431 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(2330946..2331431) Escherichia coli O157:H7 str. EC4115 6967030 YP_002270813.1 CDS astE NC_011353.1 2331761 2332729 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(2331761..2332729) Escherichia coli O157:H7 str. EC4115 6971058 YP_002270814.1 CDS astB NC_011353.1 2332722 2334065 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(2332722..2334065) Escherichia coli O157:H7 str. EC4115 6970457 YP_002270815.1 CDS astD NC_011353.1 2334062 2335540 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(2334062..2335540) Escherichia coli O157:H7 str. EC4115 6968544 YP_002270816.1 CDS astA NC_011353.1 2335537 2336571 R identified by match to protein family HMM PF04958; match to protein family HMM TIGR03243; match to protein family HMM TIGR03244; arginine succinyltransferase complement(2335537..2336571) Escherichia coli O157:H7 str. EC4115 6970231 YP_002270817.1 CDS astC NC_011353.1 2336568 2337788 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(2336568..2337788) Escherichia coli O157:H7 str. EC4115 6969746 YP_002270818.1 CDS ECH74115_2467 NC_011353.1 2338051 2338221 D identified by glimmer; hypothetical protein 2338051..2338221 Escherichia coli O157:H7 str. EC4115 6972194 YP_002270819.1 CDS xth NC_011353.1 2338234 2339040 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2338234..2339040 Escherichia coli O157:H7 str. EC4115 6967584 YP_002270820.1 CDS ECH74115_2469 NC_011353.1 2339207 2339917 D identified by match to protein family HMM PF09335; hypothetical protein 2339207..2339917 Escherichia coli O157:H7 str. EC4115 6966801 YP_002270821.1 CDS ECH74115_2470 NC_011353.1 2339922 2340599 D hypothetical protein 2339922..2340599 Escherichia coli O157:H7 str. EC4115 6968712 YP_002270822.1 CDS ECH74115_2471 NC_011353.1 2340614 2341321 D identified by match to protein family HMM PF09335; hypothetical protein 2340614..2341321 Escherichia coli O157:H7 str. EC4115 6968085 YP_002270823.1 CDS ECH74115_2472 NC_011353.1 2341321 2341869 D identified by match to protein family HMM PF02627; carboxymuconolactone decarboxylase family protein 2341321..2341869 Escherichia coli O157:H7 str. EC4115 6970731 YP_002270824.1 CDS ECH74115_2473 NC_011353.1 2341879 2343045 D identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 2341879..2343045 Escherichia coli O157:H7 str. EC4115 6969544 YP_002270825.1 CDS ynjC NC_011353.1 2343018 2344553 D ABC transporter permease 2343018..2344553 Escherichia coli O157:H7 str. EC4115 6970873 YP_002270826.1 CDS ECH74115_2475 NC_011353.1 2344553 2345206 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2344553..2345206 Escherichia coli O157:H7 str. EC4115 6970662 YP_002270827.1 CDS ECH74115_2476 NC_011353.1 2345273 2346580 D identified by match to protein family HMM PF00581; rhodanese-like domain-containing protein 2345273..2346580 Escherichia coli O157:H7 str. EC4115 6968988 YP_002270828.1 CDS ECH74115_2477 NC_011353.1 2346589 2347209 R identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase complement(2346589..2347209) Escherichia coli O157:H7 str. EC4115 6968069 YP_002270829.1 CDS nudG NC_011353.1 2347296 2347703 D identified by match to protein family HMM PF00293; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2347296..2347703 Escherichia coli O157:H7 str. EC4115 6968472 YP_002270830.1 CDS ECH74115_2478 NC_011353.1 2347669 2347941 R identified by match to protein family HMM PF07383; hypothetical protein complement(2347669..2347941) Escherichia coli O157:H7 str. EC4115 6971983 YP_002270831.1 CDS ECH74115_2480 NC_011353.1 2348026 2348139 R identified by glimmer; hypothetical protein complement(2348026..2348139) Escherichia coli O157:H7 str. EC4115 6966783 YP_002270832.1 CDS gdhA NC_011353.1 2348177 2349520 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2348177..2349520 Escherichia coli O157:H7 str. EC4115 6971333 YP_002270833.1 CDS ECH74115_2482 NC_011353.1 2349637 2350677 R hypothetical protein complement(2349637..2350677) Escherichia coli O157:H7 str. EC4115 6970650 YP_002270834.1 CDS topB NC_011353.1 2350805 2352766 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(2350805..2352766) Escherichia coli O157:H7 str. EC4115 6970094 YP_002270835.1 CDS selD NC_011353.1 2352771 2353814 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(2352771..2353814) Escherichia coli O157:H7 str. EC4115 6969610 YP_002270836.1 CDS ECH74115_2485 NC_011353.1 2353931 2354482 R identified by match to protein family HMM PF00881; hypothetical protein complement(2353931..2354482) Escherichia coli O157:H7 str. EC4115 6967581 YP_002270837.1 CDS sppA NC_011353.1 2354643 2356499 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2354643..2356499 Escherichia coli O157:H7 str. EC4115 6966725 YP_002270838.1 CDS ECH74115_2487 NC_011353.1 2356615 2357325 D identified by match to protein family HMM PF04402; hypothetical protein 2356615..2357325 Escherichia coli O157:H7 str. EC4115 6972076 YP_002270839.1 CDS ansA NC_011353.1 2357457 2358473 D converts asparagine to aspartate and ammonia; asparaginase 2357457..2358473 Escherichia coli O157:H7 str. EC4115 6971199 YP_002270840.1 CDS pncA NC_011353.1 2358484 2359125 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2358484..2359125 Escherichia coli O157:H7 str. EC4115 6970785 YP_002270841.1 CDS ECH74115_2490 NC_011353.1 2359218 2360468 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; inner membrane metabolite transport protein YdjE complement(2359218..2360468) Escherichia coli O157:H7 str. EC4115 6969915 YP_002270842.1 CDS ECH74115_2491 NC_011353.1 2360531 2360857 D overlaps another CDS with the same product name; IS629, transposase orfA 2360531..2360857 Escherichia coli O157:H7 str. EC4115 6968097 YP_002270843.1 CDS ECH74115_2492 NC_011353.1 2360857 2361744 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2360857..2361744 Escherichia coli O157:H7 str. EC4115 6970257 YP_002270844.1 CDS ECH74115_2493 NC_011353.1 2361862 2362005 D identified by glimmer; hypothetical protein 2361862..2362005 Escherichia coli O157:H7 str. EC4115 6970988 YP_002270845.1 CDS ECH74115_2494 NC_011353.1 2362007 2362765 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; DeoR family transcriptional regulator complement(2362007..2362765) Escherichia coli O157:H7 str. EC4115 6969425 YP_002270846.1 CDS ECH74115_2495 NC_011353.1 2362902 2363882 R identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family complement(2362902..2363882) Escherichia coli O157:H7 str. EC4115 6971802 YP_002270847.1 CDS ECH74115_2496 NC_011353.1 2363892 2364824 R identified by match to protein family HMM PF00294; kinase, pfkB family complement(2363892..2364824) Escherichia coli O157:H7 str. EC4115 6971036 YP_002270848.1 CDS ECH74115_2497 NC_011353.1 2364829 2365665 R identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; fructose-bisphosphate aldolase, class II family complement(2364829..2365665) Escherichia coli O157:H7 str. EC4115 6967724 YP_002270849.1 CDS gutB NC_011353.1 2365686 2366729 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; sorbitol dehydrogenase complement(2365686..2366729) Escherichia coli O157:H7 str. EC4115 6966950 YP_002270850.1 CDS ydjK NC_011353.1 2366746 2368125 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter complement(2366746..2368125) Escherichia coli O157:H7 str. EC4115 6969219 YP_002270851.1 CDS ECH74115_2500 NC_011353.1 2368152 2369228 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family complement(2368152..2369228) Escherichia coli O157:H7 str. EC4115 6968470 YP_002270852.1 CDS ECH74115_2501 NC_011353.1 2369598 2369870 R identified by match to protein family HMM PF07023; hypothetical protein complement(2369598..2369870) Escherichia coli O157:H7 str. EC4115 6970184 YP_002270853.1 CDS msrB NC_011353.1 2369912 2370325 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(2369912..2370325) Escherichia coli O157:H7 str. EC4115 6969537 YP_002270854.1 CDS gapA NC_011353.1 2370667 2371662 D identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; gIyceraldehyde-3-phosphate dehydrogenase 2370667..2371662 Escherichia coli O157:H7 str. EC4115 6967021 YP_002270855.1 CDS ECH74115_2504 NC_011353.1 2371746 2372630 D identified by match to protein family HMM PF01263; aldose 1-epimerase family protein 2371746..2372630 Escherichia coli O157:H7 str. EC4115 6969263 YP_002270856.1 CDS ECH74115_2505 NC_011353.1 2372681 2373535 R identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family complement(2372681..2373535) Escherichia coli O157:H7 str. EC4115 6967846 YP_002270857.1 CDS mipA NC_011353.1 2373625 2374371 R identified by match to protein family HMM PF06629; MltA-interacting protein MipA complement(2373625..2374371) Escherichia coli O157:H7 str. EC4115 6971226 YP_002270858.1 CDS ECH74115_2507 NC_011353.1 2374807 2376741 D identified by match to protein family HMM PF06798; match to protein family HMM PF08298; serine kinase family protein 2374807..2376741 Escherichia coli O157:H7 str. EC4115 6971836 YP_002270859.1 CDS ECH74115_2508 NC_011353.1 2376854 2378137 D identified by match to protein family HMM PF04285; hypothetical protein 2376854..2378137 Escherichia coli O157:H7 str. EC4115 6969594 YP_002270860.1 CDS ECH74115_2509 NC_011353.1 2378425 2379759 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2378425..2379759 Escherichia coli O157:H7 str. EC4115 6968207 YP_002270861.1 CDS ECH74115_2510 NC_011353.1 2379940 2381430 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2379940..2381430 Escherichia coli O157:H7 str. EC4115 6968875 YP_002270862.1 CDS ECH74115_2511 NC_011353.1 2381473 2381976 D identified by match to protein family HMM PF04073; YbaK/prolyl-tRNA synthetase-associated domain-containing protein 2381473..2381976 Escherichia coli O157:H7 str. EC4115 6966655 YP_002270863.1 CDS ECH74115_2512 NC_011353.1 2381977 2382129 R hypothetical protein complement(2381977..2382129) Escherichia coli O157:H7 str. EC4115 6967202 YP_002270864.1 CDS ECH74115_2514 NC_011353.1 2382251 2382697 D identified by match to protein family HMM PF04284; hypothetical protein 2382251..2382697 Escherichia coli O157:H7 str. EC4115 6971486 YP_002270865.1 CDS ECH74115_2513 NC_011353.1 2382654 2383463 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(2382654..2383463) Escherichia coli O157:H7 str. EC4115 6971140 YP_002270866.1 CDS yeaN NC_011353.1 2383572 2384753 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00896; inner membrane transport protein yeaN 2383572..2384753 Escherichia coli O157:H7 str. EC4115 6970189 YP_002270867.1 CDS ECH74115_2516 NC_011353.1 2384808 2385155 D identified by match to protein family HMM PF04343; hypothetical protein 2384808..2385155 Escherichia coli O157:H7 str. EC4115 6971754 YP_002270868.1 CDS ECH74115_2517 NC_011353.1 2385177 2385431 R identified by match to protein family HMM PF03891; lipoprotein complement(2385177..2385431) Escherichia coli O157:H7 str. EC4115 6968578 YP_002270869.1 CDS ECH74115_2518 NC_011353.1 2385485 2386639 D identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; GAF domain/diguanylate cyclase (GGDEF) domain-containing protein 2385485..2386639 Escherichia coli O157:H7 str. EC4115 6969205 YP_002270870.1 CDS ECH74115_2519 NC_011353.1 2386731 2386847 D hypothetical protein 2386731..2386847 Escherichia coli O157:H7 str. EC4115 6969539 YP_002270871.1 CDS ECH74115_2520 NC_011353.1 2386906 2387154 R identified by match to protein family HMM PF04226; hypothetical protein complement(2386906..2387154) Escherichia coli O157:H7 str. EC4115 6970143 YP_002270872.1 CDS ECH74115_2521 NC_011353.1 2387301 2387483 R identified by match to protein family HMM PF08956; hypothetical protein complement(2387301..2387483) Escherichia coli O157:H7 str. EC4115 6970128 YP_002270873.1 CDS ECH74115_2522 NC_011353.1 2387487 2387846 R identified by match to protein family HMM PF09313; hypothetical protein complement(2387487..2387846) Escherichia coli O157:H7 str. EC4115 6971100 YP_002270874.1 CDS ECH74115_2523 NC_011353.1 2387817 2387951 D identified by glimmer; hypothetical protein 2387817..2387951 Escherichia coli O157:H7 str. EC4115 6967033 YP_002270875.1 CDS ECH74115_2524 NC_011353.1 2388019 2388657 R identified by match to protein family HMM PF01810; leucine export protein LeuE complement(2388019..2388657) Escherichia coli O157:H7 str. EC4115 6968765 YP_002270876.1 CDS ECH74115_2525 NC_011353.1 2388784 2389707 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2388784..2389707) Escherichia coli O157:H7 str. EC4115 6971218 YP_002270877.1 CDS ttuC NC_011353.1 2389810 2390895 D identified by match to protein family HMM PF00180; match to protein family HMM TIGR02089; tartrate dehydrogenase/decarboxylase 2389810..2390895 Escherichia coli O157:H7 str. EC4115 6966852 YP_002270878.1 CDS ECH74115_2527 NC_011353.1 2391146 2392756 D member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2391146..2392756 Escherichia coli O157:H7 str. EC4115 6970101 YP_002270879.1 CDS ECH74115_2528 NC_011353.1 2392788 2393912 D identified by match to protein family HMM PF00355; Rieske 2Fe-2S domain-containing protein 2392788..2393912 Escherichia coli O157:H7 str. EC4115 6970695 YP_002270880.1 CDS ECH74115_2529 NC_011353.1 2393968 2394933 D identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein 2393968..2394933 Escherichia coli O157:H7 str. EC4115 6968666 YP_002270881.1 CDS rnd NC_011353.1 2394987 2396114 R identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D complement(2394987..2396114) Escherichia coli O157:H7 str. EC4115 6969465 YP_002270882.1 CDS fadD NC_011353.1 2396184 2397869 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2396184..2397869) Escherichia coli O157:H7 str. EC4115 6972304 YP_002270883.1 CDS slp NC_011353.1 2398074 2398655 R identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752; outer membrane protein Slp complement(2398074..2398655) Escherichia coli O157:H7 str. EC4115 6968049 YP_002270884.1 CDS ECH74115_2534 NC_011353.1 2398695 2399390 R identified by match to protein family HMM PF00814; glycoprotease family protein complement(2398695..2399390) Escherichia coli O157:H7 str. EC4115 6968262 YP_002270885.1 CDS ECH74115_2535 NC_011353.1 2399448 2401358 R hypothetical protein complement(2399448..2401358) Escherichia coli O157:H7 str. EC4115 6971732 YP_002270886.1 CDS ECH74115_2536 NC_011353.1 2401490 2401834 D identified by match to protein family HMM PF01042; endoribonuclease L-PSP family protein 2401490..2401834 Escherichia coli O157:H7 str. EC4115 6967703 YP_002270887.1 CDS ECH74115_2537 NC_011353.1 2401868 2401999 R identified by glimmer; hypothetical protein complement(2401868..2401999) Escherichia coli O157:H7 str. EC4115 6971207 YP_002270888.1 CDS ECH74115_2538 NC_011353.1 2401984 2402100 R identified by glimmer; hypothetical protein complement(2401984..2402100) Escherichia coli O157:H7 str. EC4115 6969282 YP_002270889.1 CDS ECH74115_2539 NC_011353.1 2402256 2402555 D identified by match to protein family HMM PF08986; hypothetical protein 2402256..2402555 Escherichia coli O157:H7 str. EC4115 6967082 YP_002270890.1 CDS ECH74115_2540 NC_011353.1 2402675 2402854 R identified by match to protein family HMM PF03701; hypothetical protein complement(2402675..2402854) Escherichia coli O157:H7 str. EC4115 6970343 YP_002270891.1 CDS pabB NC_011353.1 2402928 2404289 D identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553; aminodeoxychorismate synthase 2402928..2404289 Escherichia coli O157:H7 str. EC4115 6968124 YP_002270892.1 CDS ECH74115_2542 NC_011353.1 2404293 2404871 D identified by match to protein family HMM PF00293; hypothetical protein 2404293..2404871 Escherichia coli O157:H7 str. EC4115 6970768 YP_002270893.1 CDS sdaA NC_011353.1 2405055 2406419 D identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine ammonia-lyase 1 2405055..2406419 Escherichia coli O157:H7 str. EC4115 6968324 YP_002270894.1 CDS ECH74115_2544 NC_011353.1 2406550 2408148 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 2406550..2408148 Escherichia coli O157:H7 str. EC4115 6971619 YP_002270895.1 CDS ECH74115_2545 NC_011353.1 2408152 2409708 R identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein complement(2408152..2409708) Escherichia coli O157:H7 str. EC4115 6972167 YP_002270896.1 CDS manX NC_011353.1 2410171 2411142 D identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854; PTS system mannose-specific transporter subunit IIAB 2410171..2411142 Escherichia coli O157:H7 str. EC4115 6969990 YP_002270897.1 CDS manY NC_011353.1 2411205 2412005 D identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822; PTS system mannose-specific transporter subunit IIC 2411205..2412005 Escherichia coli O157:H7 str. EC4115 6970706 YP_002270898.1 CDS manZ NC_011353.1 2412018 2412869 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2412018..2412869 Escherichia coli O157:H7 str. EC4115 6968838 YP_002270899.1 CDS ECH74115_2549 NC_011353.1 2412924 2413382 D identified by match to protein family HMM PF06173; hypothetical protein 2412924..2413382 Escherichia coli O157:H7 str. EC4115 6966823 YP_002270900.1 CDS ECH74115_2551 NC_011353.1 2413693 2413815 D identified by glimmer; hypothetical protein 2413693..2413815 Escherichia coli O157:H7 str. EC4115 6967497 YP_002270901.1 CDS ECH74115_2553 NC_011353.1 2413812 2414378 D membrane protein YebN; hypothetical protein 2413812..2414378 Escherichia coli O157:H7 str. EC4115 6971350 YP_002270902.1 CDS rrmA NC_011353.1 2414375 2415184 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A complement(2414375..2415184) Escherichia coli O157:H7 str. EC4115 6970057 YP_002270903.1 CDS cspC NC_011353.1 2415350 2415559 R identified by match to protein family HMM PF00313; cold shock-like protein CspC complement(2415350..2415559) Escherichia coli O157:H7 str. EC4115 6971895 YP_002270904.1 CDS ECH74115_2555 NC_011353.1 2415572 2415715 R hypothetical protein complement(2415572..2415715) Escherichia coli O157:H7 str. EC4115 6968077 YP_002270905.1 CDS ECH74115_2556 NC_011353.1 2416384 2416671 R hypothetical protein complement(2416384..2416671) Escherichia coli O157:H7 str. EC4115 6966841 YP_002270906.1 CDS ECH74115_2557 NC_011353.1 2416746 2416889 R hypothetical protein complement(2416746..2416889) Escherichia coli O157:H7 str. EC4115 6971211 YP_002270907.1 CDS ECH74115_2558 NC_011353.1 2417049 2417288 D hypothetical protein 2417049..2417288 Escherichia coli O157:H7 str. EC4115 6970700 YP_002270908.1 CDS kdgR NC_011353.1 2417432 2418223 R identified by match to protein family HMM PF01614; match to protein family HMM PF09339; transcriptional regulator KdgR complement(2417432..2418223) Escherichia coli O157:H7 str. EC4115 6970075 YP_002270909.1 CDS ECH74115_2560 NC_011353.1 2418400 2419773 D identified by match to protein family HMM PF07690; major facilitator family transporter 2418400..2419773 Escherichia coli O157:H7 str. EC4115 6968803 YP_002270910.1 CDS ECH74115_2561 NC_011353.1 2419819 2420700 R metalloprotease; heat shock protein HtpX complement(2419819..2420700) Escherichia coli O157:H7 str. EC4115 6968006 YP_002270911.1 CDS ECH74115_2562 NC_011353.1 2420795 2420935 R identified by glimmer; hypothetical protein complement(2420795..2420935) Escherichia coli O157:H7 str. EC4115 6967593 YP_002270912.1 CDS prc NC_011353.1 2420892 2422934 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2420892..2422934) Escherichia coli O157:H7 str. EC4115 6971820 YP_002270913.1 CDS proQ NC_011353.1 2422960 2423658 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(2422960..2423658) Escherichia coli O157:H7 str. EC4115 6971021 YP_002270914.1 CDS ECH74115_2565 NC_011353.1 2423755 2424252 R identified by match to protein family HMM PF01590; GAF domain-containing protein complement(2423755..2424252) Escherichia coli O157:H7 str. EC4115 6970217 YP_002270915.1 CDS ECH74115_2566 NC_011353.1 2424382 2425665 D identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155; PqiA family integral membrane protein 2424382..2425665 Escherichia coli O157:H7 str. EC4115 6968339 YP_002270916.1 CDS ECH74115_2567 NC_011353.1 2425628 2428267 D identified by match to protein family HMM PF02470; mce-like protein 2425628..2428267 Escherichia coli O157:H7 str. EC4115 6969631 YP_002270917.1 CDS yebU NC_011353.1 2428348 2429787 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2428348..2429787 Escherichia coli O157:H7 str. EC4115 6971987 YP_002270918.1 CDS ECH74115_2569 NC_011353.1 2429905 2430141 D identified by match to protein family HMM PF07351; hypothetical protein 2429905..2430141 Escherichia coli O157:H7 str. EC4115 6970860 YP_002270919.1 CDS ECH74115_2570 NC_011353.1 2430246 2430437 D identified by match to protein family HMM PF07358; hypothetical protein 2430246..2430437 Escherichia coli O157:H7 str. EC4115 6967580 YP_002270920.1 CDS pphA NC_011353.1 2430438 2431094 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2430438..2431094) Escherichia coli O157:H7 str. EC4115 6968800 YP_002270921.1 CDS ECH74115_2574 NC_011353.1 2431490 2431831 R hypothetical protein complement(2431490..2431831) Escherichia coli O157:H7 str. EC4115 6972297 YP_002270922.1 CDS ECH74115_2575 NC_011353.1 2431844 2432716 R identified by match to protein family HMM PF05425; copper resistance protein D complement(2431844..2432716) Escherichia coli O157:H7 str. EC4115 6968354 YP_002270923.1 CDS ECH74115_2576 NC_011353.1 2432720 2433094 R identified by match to protein family HMM PF04234; hypothetical protein complement(2432720..2433094) Escherichia coli O157:H7 str. EC4115 6970767 YP_002270924.1 CDS holE NC_011353.1 2433233 2433463 D identified by match to protein family HMM PF06440; DNA polymerase III subunit theta 2433233..2433463 Escherichia coli O157:H7 str. EC4115 6971929 YP_002270925.1 CDS ECH74115_2578 NC_011353.1 2433565 2434221 D identified by match to protein family HMM PF00795; hydrolase 2433565..2434221 Escherichia coli O157:H7 str. EC4115 6971933 YP_002270926.1 CDS exoX NC_011353.1 2434245 2434907 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2434245..2434907 Escherichia coli O157:H7 str. EC4115 6970274 YP_002270927.1 CDS prtB NC_011353.1 2434904 2436964 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(2434904..2436964) Escherichia coli O157:H7 str. EC4115 6969210 YP_002270928.1 CDS ECH74115_2581 NC_011353.1 2437173 2437832 R identified by match to protein family HMM PF04391; hypothetical protein complement(2437173..2437832) Escherichia coli O157:H7 str. EC4115 6969649 YP_002270929.1 CDS ECH74115_2582 NC_011353.1 2438159 2438527 R secreted protein; unknown function; hypothetical protein complement(2438159..2438527) Escherichia coli O157:H7 str. EC4115 6968019 YP_002270930.1 CDS ECH74115_2583 NC_011353.1 2438582 2438872 R identified by match to protein family HMM PF07130; DNA damage-inducible protein YebG complement(2438582..2438872) Escherichia coli O157:H7 str. EC4115 6967864 YP_002270931.1 CDS purT NC_011353.1 2439006 2440184 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2439006..2440184 Escherichia coli O157:H7 str. EC4115 6967071 YP_002270932.1 CDS eda NC_011353.1 2440240 2440881 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2440240..2440881) Escherichia coli O157:H7 str. EC4115 6971520 YP_002270933.1 CDS edd NC_011353.1 2440918 2442729 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2440918..2442729) Escherichia coli O157:H7 str. EC4115 6971458 YP_002270934.1 CDS zwf NC_011353.1 2442964 2444439 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2442964..2444439) Escherichia coli O157:H7 str. EC4115 6970446 YP_002270935.1 CDS ECH74115_2588 NC_011353.1 2444605 2444754 R hypothetical protein complement(2444605..2444754) Escherichia coli O157:H7 str. EC4115 6967227 YP_002270936.1 CDS ECH74115_2589 NC_011353.1 2444777 2445646 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2444777..2445646 Escherichia coli O157:H7 str. EC4115 6970875 YP_002270937.1 CDS pykA NC_011353.1 2445774 2447216 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2445774..2447216 Escherichia coli O157:H7 str. EC4115 6971703 YP_002270938.1 CDS msbB NC_011353.1 2447347 2448318 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2447347..2448318) Escherichia coli O157:H7 str. EC4115 6968239 YP_002270939.1 CDS ECH74115_2592 NC_011353.1 2448438 2449760 R identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525; hypothetical protein complement(2448438..2449760) Escherichia coli O157:H7 str. EC4115 6968844 YP_002270940.1 CDS znuA NC_011353.1 2449776 2450708 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(2449776..2450708) Escherichia coli O157:H7 str. EC4115 6966995 YP_002270941.1 CDS znuC NC_011353.1 2450787 2451542 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2450787..2451542 Escherichia coli O157:H7 str. EC4115 6967598 YP_002270942.1 CDS znuB NC_011353.1 2451539 2452324 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2451539..2452324 Escherichia coli O157:H7 str. EC4115 6971467 YP_002270943.1 CDS ruvB NC_011353.1 2452570 2453580 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2452570..2453580) Escherichia coli O157:H7 str. EC4115 6972073 YP_002270944.1 CDS ruvA NC_011353.1 2453589 2454200 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2453589..2454200) Escherichia coli O157:H7 str. EC4115 6970165 YP_002270945.1 CDS ECH74115_2598 NC_011353.1 2454475 2455077 D identified by match to protein family HMM PF06520; hypothetical protein 2454475..2455077 Escherichia coli O157:H7 str. EC4115 6967118 YP_002270946.1 CDS ruvC NC_011353.1 2455079 2455600 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2455079..2455600) Escherichia coli O157:H7 str. EC4115 6969142 YP_002270947.1 CDS ECH74115_2600 NC_011353.1 2455635 2456375 R identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein complement(2455635..2456375) Escherichia coli O157:H7 str. EC4115 6968379 YP_002270948.1 CDS ntpA NC_011353.1 2456404 2456913 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2456404..2456913) Escherichia coli O157:H7 str. EC4115 6971540 YP_002270949.1 CDS aspS NC_011353.1 2456974 2458746 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2456974..2458746) Escherichia coli O157:H7 str. EC4115 6971094 YP_002270950.1 CDS ECH74115_2603 NC_011353.1 2459056 2459622 D identified by match to protein family HMM PF00857; hypothetical protein 2459056..2459622 Escherichia coli O157:H7 str. EC4115 6967914 YP_002270951.1 CDS ECH74115_2604 NC_011353.1 2459619 2460437 D identified by match to protein family HMM PF01904; hypothetical protein 2459619..2460437 Escherichia coli O157:H7 str. EC4115 6967128 YP_002270952.1 CDS ECH74115_2605 NC_011353.1 2460490 2460885 D inner membrane protein 2460490..2460885 Escherichia coli O157:H7 str. EC4115 6968320 YP_002270953.1 CDS ECH74115_2606 NC_011353.1 2460926 2461669 D overlaps another CDS with the same product name; identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740; methyltransferase 2460926..2461669 Escherichia coli O157:H7 str. EC4115 6967887 YP_002270954.1 CDS ECH74115_2607 NC_011353.1 2461666 2462637 D overlaps another CDS with the same product name; identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452; methyltransferase 2461666..2462637 Escherichia coli O157:H7 str. EC4115 6970296 YP_002270955.1 CDS torZ NC_011353.1 2462802 2465231 R identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; trimethylamine N-oxide reductase III subunit TorZ complement(2462802..2465231) Escherichia coli O157:H7 str. EC4115 6970591 YP_002270956.1 CDS torY NC_011353.1 2465256 2466356 R identified by match to protein family HMM PF03264; trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY complement(2465256..2466356) Escherichia coli O157:H7 str. EC4115 6971204 YP_002270957.1 CDS cutC NC_011353.1 2466744 2467490 R identified by match to protein family HMM PF03932; copper homeostasis protein CutC complement(2466744..2467490) Escherichia coli O157:H7 str. EC4115 6972136 YP_002270958.1 CDS ECH74115_2611 NC_011353.1 2467504 2468076 R identified by match to protein family HMM PF06185; hypothetical protein complement(2467504..2468076) Escherichia coli O157:H7 str. EC4115 6967848 YP_002270959.1 CDS ECH74115_2612 NC_011353.1 2468139 2468252 R hypothetical protein complement(2468139..2468252) Escherichia coli O157:H7 str. EC4115 6970918 YP_002270960.1 CDS argS NC_011353.1 2468286 2470019 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2468286..2470019 Escherichia coli O157:H7 str. EC4115 6968701 YP_002270961.1 CDS ECH74115_2614 NC_011353.1 2470196 2470684 D identified by match to protein family HMM PF07007; hypothetical protein 2470196..2470684 Escherichia coli O157:H7 str. EC4115 6966786 YP_002270962.1 CDS flhE NC_011353.1 2470804 2471040 R identified by match to protein family HMM PF06366; flagellar protein FlhE complement(2470804..2471040) Escherichia coli O157:H7 str. EC4115 6972246 YP_002270963.1 CDS flhA NC_011353.1 2471196 2473274 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2471196..2473274) Escherichia coli O157:H7 str. EC4115 6969794 YP_002270964.1 CDS flhB NC_011353.1 2473267 2474415 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2473267..2474415) Escherichia coli O157:H7 str. EC4115 6967627 YP_002270965.1 CDS cheZ NC_011353.1 2474617 2475261 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2474617..2475261) Escherichia coli O157:H7 str. EC4115 6968288 YP_002270966.1 CDS cheY NC_011353.1 2475272 2475661 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2475272..2475661) Escherichia coli O157:H7 str. EC4115 6970173 YP_002270967.1 CDS cheB NC_011353.1 2475676 2476725 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2475676..2476725) Escherichia coli O157:H7 str. EC4115 6967324 YP_002270968.1 CDS cheR NC_011353.1 2476728 2477588 R methylates the MCP; chemotaxis methyltransferase CheR complement(2476728..2477588) Escherichia coli O157:H7 str. EC4115 6966676 YP_002270969.1 CDS tap NC_011353.1 2477607 2479208 R mediates taxis toward dipeptides; methyl-accepting protein IV complement(2477607..2479208) Escherichia coli O157:H7 str. EC4115 6971441 YP_002270970.1 CDS tar NC_011353.1 2479254 2480915 R identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein II complement(2479254..2480915) Escherichia coli O157:H7 str. EC4115 6967904 YP_002270971.1 CDS cheW NC_011353.1 2481058 2481561 R identified by match to protein family HMM PF01584; purine-binding chemotaxis protein complement(2481058..2481561) Escherichia coli O157:H7 str. EC4115 6972306 YP_002270972.1 CDS cheA NC_011353.1 2481582 2483540 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(2481582..2483540) Escherichia coli O157:H7 str. EC4115 6969829 YP_002270973.1 CDS motB NC_011353.1 2483551 2484477 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2483551..2484477) Escherichia coli O157:H7 str. EC4115 6968859 YP_002270974.1 CDS motA NC_011353.1 2484474 2485361 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2484474..2485361) Escherichia coli O157:H7 str. EC4115 6968393 YP_002270975.1 CDS flhC NC_011353.1 2485488 2486066 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2485488..2486066) Escherichia coli O157:H7 str. EC4115 6967415 YP_002270976.1 CDS flhD NC_011353.1 2486069 2486419 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2486069..2486419) Escherichia coli O157:H7 str. EC4115 6967137 YP_002270977.1 CDS uspC NC_011353.1 2487199 2487627 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2487199..2487627 Escherichia coli O157:H7 str. EC4115 6969648 YP_002270978.1 CDS otsA NC_011353.1 2487634 2489058 R identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400; trehalose-6-phosphate synthase complement(2487634..2489058) Escherichia coli O157:H7 str. EC4115 6971571 YP_002270979.1 CDS otsB NC_011353.1 2489033 2489833 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2489033..2489833) Escherichia coli O157:H7 str. EC4115 6969072 YP_002270980.1 CDS araH NC_011353.1 2490000 2490986 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(2490000..2490986) Escherichia coli O157:H7 str. EC4115 6968475 YP_002270981.1 CDS araG NC_011353.1 2491001 2492515 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2491001..2492515) Escherichia coli O157:H7 str. EC4115 6967234 YP_002270982.1 CDS araF NC_011353.1 2492585 2493574 R identified by match to protein family HMM PF00532; L-arabinose ABC transporter substrate-binding protein complement(2492585..2493574) Escherichia coli O157:H7 str. EC4115 6969060 YP_002270983.1 CDS ECH74115_2638 NC_011353.1 2494371 2494874 D identified by match to protein family HMM PF00210; ferritin family protein 2494371..2494874 Escherichia coli O157:H7 str. EC4115 6970985 YP_002270984.1 CDS ECH74115_2639 NC_011353.1 2494954 2495205 R hypothetical protein complement(2494954..2495205) Escherichia coli O157:H7 str. EC4115 6970083 YP_002270985.1 CDS ECH74115_2640 NC_011353.1 2495317 2495463 D identified by glimmer; hypothetical protein 2495317..2495463 Escherichia coli O157:H7 str. EC4115 6968936 YP_002270986.1 CDS ECH74115_2641 NC_011353.1 2495552 2495695 R identified by glimmer; hypothetical protein complement(2495552..2495695) Escherichia coli O157:H7 str. EC4115 6968148 YP_002270987.1 CDS ECH74115_2642 NC_011353.1 2495737 2495991 D lipoprotein 2495737..2495991 Escherichia coli O157:H7 str. EC4115 6971846 YP_002270988.1 CDS ECH74115_2643 NC_011353.1 2495997 2496137 R identified by glimmer; hypothetical protein complement(2495997..2496137) Escherichia coli O157:H7 str. EC4115 6971052 YP_002270989.1 CDS ftnA NC_011353.1 2496162 2496659 D cytoplasmic iron storage protein; ferritin 2496162..2496659 Escherichia coli O157:H7 str. EC4115 6970252 YP_002270990.1 CDS ECH74115_2645 NC_011353.1 2496696 2496935 R hypothetical protein complement(2496696..2496935) Escherichia coli O157:H7 str. EC4115 6969449 YP_002270991.1 CDS ECH74115_2646 NC_011353.1 2497075 2497173 R identified by glimmer; hypothetical protein complement(2497075..2497173) Escherichia coli O157:H7 str. EC4115 6968309 YP_002270992.1 CDS tyrP NC_011353.1 2497127 2498338 D identified by match to protein family HMM PF03222; match to protein family HMM TIGR00837; tyrosine-specific transport protein 2497127..2498338 Escherichia coli O157:H7 str. EC4115 6970736 YP_002270993.1 CDS ECH74115_2648 NC_011353.1 2498400 2499065 R identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292; hypothetical protein complement(2498400..2499065) Escherichia coli O157:H7 str. EC4115 6966791 YP_002270994.1 CDS ECH74115_2649 NC_011353.1 2499422 2500423 R identified by match to protein family HMM PF00589; integrase family protein complement(2499422..2500423) Escherichia coli O157:H7 str. EC4115 6972236 YP_002270995.1 CDS ECH74115_2650 NC_011353.1 2500429 2500776 R hypothetical protein complement(2500429..2500776) Escherichia coli O157:H7 str. EC4115 6966555 YP_002270996.1 CDS ECH74115_2651 NC_011353.1 2500806 2501456 R hypothetical protein complement(2500806..2501456) Escherichia coli O157:H7 str. EC4115 6967471 YP_002270997.1 CDS ECH74115_2652 NC_011353.1 2501472 2501732 R transcriptional regulator complement(2501472..2501732) Escherichia coli O157:H7 str. EC4115 6968257 YP_002270998.1 CDS ECH74115_2653 NC_011353.1 2502175 2502378 D DNA-binding protein 2502175..2502378 Escherichia coli O157:H7 str. EC4115 6966978 YP_002270999.1 CDS ECH74115_2654 NC_011353.1 2502400 2502750 D hypothetical protein 2502400..2502750 Escherichia coli O157:H7 str. EC4115 6970625 YP_002271000.1 CDS ECH74115_2655 NC_011353.1 2502761 2503039 D hypothetical protein 2502761..2503039 Escherichia coli O157:H7 str. EC4115 6968529 YP_002271001.1 CDS ECH74115_2656 NC_011353.1 2503051 2503293 D hypothetical protein 2503051..2503293 Escherichia coli O157:H7 str. EC4115 6970115 YP_002271002.1 CDS ECH74115_2657 NC_011353.1 2503290 2503403 D identified by glimmer; hypothetical protein 2503290..2503403 Escherichia coli O157:H7 str. EC4115 6968032 YP_002271003.1 CDS ECH74115_2658 NC_011353.1 2503496 2503912 D hypothetical protein 2503496..2503912 Escherichia coli O157:H7 str. EC4115 6969907 YP_002271004.1 CDS ECH74115_2659 NC_011353.1 2503936 2504139 D hypothetical protein 2503936..2504139 Escherichia coli O157:H7 str. EC4115 6967992 YP_002271005.1 CDS ECH74115_2660 NC_011353.1 2504399 2504698 D hypothetical protein 2504399..2504698 Escherichia coli O157:H7 str. EC4115 6971502 YP_002271006.1 CDS ECH74115_2661 NC_011353.1 2505021 2505251 D hypothetical protein 2505021..2505251 Escherichia coli O157:H7 str. EC4115 6970698 YP_002271007.1 CDS ECH74115_2662 NC_011353.1 2505324 2505689 D hypothetical protein 2505324..2505689 Escherichia coli O157:H7 str. EC4115 6967032 YP_002271008.1 CDS ECH74115_2663 NC_011353.1 2505696 2508518 D identified by match to protein family HMM PF05840; bacteriophage replication gene A protein 2505696..2508518 Escherichia coli O157:H7 str. EC4115 6971822 YP_002271009.1 CDS ECH74115_2664 NC_011353.1 2508595 2509554 D identified by match to protein family HMM PF06406; plasmid segregation protein ParM 2508595..2509554 Escherichia coli O157:H7 str. EC4115 6968271 YP_002271010.1 CDS ECH74115_2665 NC_011353.1 2509893 2510582 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; transposase complement(2509893..2510582) Escherichia coli O157:H7 str. EC4115 6967372 YP_002271011.1 CDS ECH74115_2666 NC_011353.1 2510582 2510908 R overlaps another CDS with the same product name; IS629, transposase orfA complement(2510582..2510908) Escherichia coli O157:H7 str. EC4115 6968137 YP_002271012.1 CDS ECH74115_2667 NC_011353.1 2511079 2511495 D identified by match to protein family HMM PF02413; tail fiber assembly protein-like protein 2511079..2511495 Escherichia coli O157:H7 str. EC4115 6967366 YP_002271013.1 CDS ECH74115_2668 NC_011353.1 2511539 2512015 R identified by match to protein family HMM PF00132; serine acetlyltransferase of prophage CP-933T complement(2511539..2512015) Escherichia coli O157:H7 str. EC4115 6969891 YP_002271014.1 CDS ECH74115_2669 NC_011353.1 2512268 2512756 R identified by match to protein family HMM PF06995; P2 GpU family protein complement(2512268..2512756) Escherichia coli O157:H7 str. EC4115 6968103 YP_002271015.1 CDS ECH74115_2672 NC_011353.1 2515559 2515714 R identified by match to protein family HMM PF06528; phage tail protein, P2 GpE family complement(2515559..2515714) Escherichia coli O157:H7 str. EC4115 6971898 YP_002271016.1 CDS ECH74115_2673 NC_011353.1 2515723 2516088 R identified by match to protein family HMM PF06158; phage tail protein E complement(2515723..2516088) Escherichia coli O157:H7 str. EC4115 6971321 YP_002271017.1 CDS ECH74115_2674 NC_011353.1 2516143 2516655 R identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611; phage major tail tube protein complement(2516143..2516655) Escherichia coli O157:H7 str. EC4115 6971040 YP_002271018.1 CDS ECH74115_2675 NC_011353.1 2516655 2517839 R identified by match to protein family HMM PF04984; phage tail sheath protein complement(2516655..2517839) Escherichia coli O157:H7 str. EC4115 6970428 YP_002271019.1 CDS ECH74115_2676 NC_011353.1 2517819 2517950 D identified by glimmer; hypothetical protein 2517819..2517950 Escherichia coli O157:H7 str. EC4115 6970400 YP_002271020.1 CDS ECH74115_2678 NC_011353.1 2517997 2518320 D tail protein 2517997..2518320 Escherichia coli O157:H7 str. EC4115 6969169 YP_002271021.1 CDS ECH74115_2677 NC_011353.1 2518271 2519335 R identified by match to protein family HMM PF00665; transposase InsI for insertion sequence element IS30B/C/D complement(2518271..2519335) Escherichia coli O157:H7 str. EC4115 6968950 YP_002271022.1 CDS ECH74115_2679 NC_011353.1 2519297 2519623 D overlaps another CDS with the same product name; IS629, transposase orfA 2519297..2519623 Escherichia coli O157:H7 str. EC4115 6968352 YP_002271023.1 CDS ECH74115_2680 NC_011353.1 2519623 2520510 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2519623..2520510 Escherichia coli O157:H7 str. EC4115 6969834 YP_002271024.1 CDS pgsA NC_011353.1 2522150 2522698 R identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; phosphatidylglycerophosphate synthetase complement(2522150..2522698) Escherichia coli O157:H7 str. EC4115 6972357 YP_002271025.1 CDS uvrC NC_011353.1 2522755 2524587 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2522755..2524587) Escherichia coli O157:H7 str. EC4115 6971395 YP_002271026.1 CDS uvrY NC_011353.1 2524584 2525240 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2524584..2525240) Escherichia coli O157:H7 str. EC4115 6972177 YP_002271027.1 CDS ECH74115_2687 NC_011353.1 2525382 2525498 D identified by glimmer; hypothetical protein 2525382..2525498 Escherichia coli O157:H7 str. EC4115 6967281 YP_002271028.1 CDS ECH74115_2688 NC_011353.1 2525536 2525712 D identified by glimmer; hypothetical protein 2525536..2525712 Escherichia coli O157:H7 str. EC4115 6968060 YP_002271029.1 CDS ECH74115_2689 NC_011353.1 2525699 2525923 D hypothetical protein 2525699..2525923 Escherichia coli O157:H7 str. EC4115 6969026 YP_002271030.1 CDS sdiA NC_011353.1 2525991 2526713 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2525991..2526713) Escherichia coli O157:H7 str. EC4115 6969782 YP_002271031.1 CDS yecC NC_011353.1 2526943 2527695 R identified by match to protein family HMM PF00005; amino-acid ABC transporter ATP-binding protein YecC complement(2526943..2527695) Escherichia coli O157:H7 str. EC4115 6970391 YP_002271032.1 CDS ECH74115_2692 NC_011353.1 2527692 2528360 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; L-cystine ABC transporter permease complement(2527692..2528360) Escherichia coli O157:H7 str. EC4115 6968704 YP_002271033.1 CDS dcyD NC_011353.1 2528375 2529361 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2528375..2529361) Escherichia coli O157:H7 str. EC4115 6968508 YP_002271034.1 CDS fliY NC_011353.1 2529466 2530266 R identified by match to protein family HMM PF00497; cystine transporter subunit complement(2529466..2530266) Escherichia coli O157:H7 str. EC4115 6971355 YP_002271035.1 CDS ECH74115_2695 NC_011353.1 2530354 2530905 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2530354..2530905) Escherichia coli O157:H7 str. EC4115 6967674 YP_002271036.1 CDS fliA NC_011353.1 2530951 2531670 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2530951..2531670) Escherichia coli O157:H7 str. EC4115 6971865 YP_002271037.1 CDS ECH74115_2697 NC_011353.1 2531744 2531863 D identified by glimmer; hypothetical protein 2531744..2531863 Escherichia coli O157:H7 str. EC4115 6971078 YP_002271038.1 CDS ECH74115_2698 NC_011353.1 2531990 2533747 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2531990..2533747) Escherichia coli O157:H7 str. EC4115 6968196 YP_002271039.1 CDS fliD NC_011353.1 2534013 2535410 D involved in flagellin assembly; flagellar capping protein 2534013..2535410 Escherichia coli O157:H7 str. EC4115 6970253 YP_002271040.1 CDS fliS NC_011353.1 2535435 2535845 D flagellin specific chaperone; flagellar protein FliS 2535435..2535845 Escherichia coli O157:H7 str. EC4115 6966556 YP_002271041.1 CDS fliT NC_011353.1 2535845 2536210 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2535845..2536210 Escherichia coli O157:H7 str. EC4115 6967150 YP_002271042.1 CDS amyA NC_011353.1 2536288 2537775 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2536288..2537775 Escherichia coli O157:H7 str. EC4115 6970415 YP_002271043.1 CDS ECH74115_2703 NC_011353.1 2537809 2538222 R hypothetical protein complement(2537809..2538222) Escherichia coli O157:H7 str. EC4115 6969592 YP_002271044.1 CDS ECH74115_2704 NC_011353.1 2538409 2539614 D identified by match to protein family HMM PF04143; inner membrane protein 2538409..2539614 Escherichia coli O157:H7 str. EC4115 6968229 YP_002271045.1 CDS ECH74115_2705 NC_011353.1 2539611 2539844 D identified by match to protein family HMM PF01206; hypothetical protein 2539611..2539844 Escherichia coli O157:H7 str. EC4115 6970468 YP_002271046.1 CDS ECH74115_2706 NC_011353.1 2539953 2540621 D identified by match to protein family HMM PF02586; hypothetical protein 2539953..2540621 Escherichia coli O157:H7 str. EC4115 6967136 YP_002271047.1 CDS ECH74115_2707 NC_011353.1 2540732 2541211 D identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2540732..2541211 Escherichia coli O157:H7 str. EC4115 6969368 YP_002271048.1 CDS ECH74115_2708 NC_011353.1 2541349 2542488 R identified by glimmer; hypothetical protein complement(2541349..2542488) Escherichia coli O157:H7 str. EC4115 6969526 YP_002271049.1 CDS ECH74115_2710 NC_011353.1 2542870 2543169 D identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2542870..2543169 Escherichia coli O157:H7 str. EC4115 6968907 YP_002271050.1 CDS ECH74115_2709 NC_011353.1 2543143 2543259 R identified by glimmer; hypothetical protein complement(2543143..2543259) Escherichia coli O157:H7 str. EC4115 6970458 YP_002271051.1 CDS ECH74115_2711 NC_011353.1 2543307 2544446 R identified by glimmer; hypothetical protein complement(2543307..2544446) Escherichia coli O157:H7 str. EC4115 6971077 YP_002271052.1 CDS fliE NC_011353.1 2544795 2545109 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2544795..2545109) Escherichia coli O157:H7 str. EC4115 6968982 YP_002271053.1 CDS ECH74115_2713 NC_011353.1 2545154 2545303 R hypothetical protein complement(2545154..2545303) Escherichia coli O157:H7 str. EC4115 6966917 YP_002271054.1 CDS fliF NC_011353.1 2545324 2546982 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2545324..2546982 Escherichia coli O157:H7 str. EC4115 6968515 YP_002271055.1 CDS fliG NC_011353.1 2546975 2547970 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2546975..2547970 Escherichia coli O157:H7 str. EC4115 6966665 YP_002271056.1 CDS fliH NC_011353.1 2547963 2548649 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2547963..2548649 Escherichia coli O157:H7 str. EC4115 6966992 YP_002271057.1 CDS fliI NC_011353.1 2548711 2550084 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2548711..2550084 Escherichia coli O157:H7 str. EC4115 6967634 YP_002271058.1 CDS fliJ NC_011353.1 2550103 2550546 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2550103..2550546 Escherichia coli O157:H7 str. EC4115 6971178 YP_002271059.1 CDS fliK NC_011353.1 2550543 2551670 D identified by match to protein family HMM PF02120; flagellar hook-length control protein 2550543..2551670 Escherichia coli O157:H7 str. EC4115 6972077 YP_002271060.1 CDS fliL NC_011353.1 2551775 2552239 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2551775..2552239 Escherichia coli O157:H7 str. EC4115 6969497 YP_002271061.1 CDS fliM NC_011353.1 2552244 2553248 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2552244..2553248 Escherichia coli O157:H7 str. EC4115 6970424 YP_002271062.1 CDS fliN NC_011353.1 2553245 2553658 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2553245..2553658 Escherichia coli O157:H7 str. EC4115 6967259 YP_002271063.1 CDS ECH74115_2722 NC_011353.1 2553621 2553743 R identified by glimmer; hypothetical protein complement(2553621..2553743) Escherichia coli O157:H7 str. EC4115 6967903 YP_002271064.1 CDS fliO NC_011353.1 2553721 2554026 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2553721..2554026 Escherichia coli O157:H7 str. EC4115 6971472 YP_002271065.1 CDS fliP NC_011353.1 2554026 2554763 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2554026..2554763 Escherichia coli O157:H7 str. EC4115 6971442 YP_002271066.1 CDS fliQ NC_011353.1 2554773 2555042 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2554773..2555042 Escherichia coli O157:H7 str. EC4115 6971751 YP_002271067.1 CDS fliR NC_011353.1 2555050 2555835 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2555050..2555835 Escherichia coli O157:H7 str. EC4115 6969432 YP_002271068.1 CDS rcsA NC_011353.1 2556125 2556748 D identified by match to protein family HMM PF00196; colanic acid capsular biosynthesis activation protein A 2556125..2556748 Escherichia coli O157:H7 str. EC4115 6970521 YP_002271069.1 CDS ECH74115_2729 NC_011353.1 2556792 2556980 R hypothetical protein complement(2556792..2556980) Escherichia coli O157:H7 str. EC4115 6970309 YP_002271070.1 CDS ECH74115_2730 NC_011353.1 2557143 2557370 D hypothetical protein 2557143..2557370 Escherichia coli O157:H7 str. EC4115 6969274 YP_002271071.1 CDS ECH74115_2733 NC_011353.1 2557668 2558483 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2557668..2558483 Escherichia coli O157:H7 str. EC4115 6972312 YP_002271072.1 CDS ECH74115_2732 NC_011353.1 2558480 2560174 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(2558480..2560174) Escherichia coli O157:H7 str. EC4115 6968962 YP_002271073.1 CDS ECH74115_2735 NC_011353.1 2560606 2561523 R identified by match to protein family HMM PF05661; hypothetical protein complement(2560606..2561523) Escherichia coli O157:H7 str. EC4115 6966730 YP_002271074.1 CDS ECH74115_2737 NC_011353.1 2561696 2562616 D identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; hypothetical protein 2561696..2562616 Escherichia coli O157:H7 str. EC4115 6967365 YP_002271075.1 CDS vsr NC_011353.1 2562605 2563075 R identified by match to protein family HMM PF03852; match to protein family HMM TIGR00632; very short patch repair protein complement(2562605..2563075) Escherichia coli O157:H7 str. EC4115 6972084 YP_002271076.1 CDS dcm NC_011353.1 2563056 2564474 R identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; DNA cytosine methylase complement(2563056..2564474) Escherichia coli O157:H7 str. EC4115 6970819 YP_002271077.1 CDS ECH74115_2739 NC_011353.1 2564541 2565236 R identified by match to protein family HMM PF01966; hypothetical protein complement(2564541..2565236) Escherichia coli O157:H7 str. EC4115 6971380 YP_002271078.1 CDS ECH74115_2744 NC_011353.1 2567602 2567724 R identified by glimmer; hypothetical protein complement(2567602..2567724) Escherichia coli O157:H7 str. EC4115 6967124 YP_002271079.1 CDS ECH74115_2745 NC_011353.1 2567821 2567964 D identified by glimmer; hypothetical protein 2567821..2567964 Escherichia coli O157:H7 str. EC4115 6970667 YP_002271080.1 CDS hchA NC_011353.1 2567985 2568836 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2567985..2568836 Escherichia coli O157:H7 str. EC4115 6971307 YP_002271081.1 CDS ECH74115_2747 NC_011353.1 2568944 2570302 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; heavy metal sensor histidine kinase complement(2568944..2570302) Escherichia coli O157:H7 str. EC4115 6968824 YP_002271082.1 CDS ECH74115_2748 NC_011353.1 2570302 2571003 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2570302..2571003) Escherichia coli O157:H7 str. EC4115 6969579 YP_002271083.1 CDS ECH74115_2749 NC_011353.1 2571106 2571519 D identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962; transthyretin family protein 2571106..2571519 Escherichia coli O157:H7 str. EC4115 6969932 YP_002271084.1 CDS ECH74115_2750 NC_011353.1 2571627 2572631 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2571627..2572631 Escherichia coli O157:H7 str. EC4115 6969147 YP_002271085.1 CDS ECH74115_2751 NC_011353.1 2572632 2573267 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2572632..2573267 Escherichia coli O157:H7 str. EC4115 6969000 YP_002271086.1 CDS ECH74115_2752 NC_011353.1 2573524 2574174 D identified by match to protein family HMM PF09223; hypothetical protein 2573524..2574174 Escherichia coli O157:H7 str. EC4115 6968212 YP_002271087.1 CDS ECH74115_2753 NC_011353.1 2574517 2575047 D identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit 2574517..2575047 Escherichia coli O157:H7 str. EC4115 6971046 YP_002271088.1 CDS ECH74115_2754 NC_011353.1 2576184 2576837 D non-LEE-encoded effector EspJ 2576184..2576837 Escherichia coli O157:H7 str. EC4115 6971761 YP_002271089.1 CDS ECH74115_2755 NC_011353.1 2577146 2577310 R identified by glimmer; hypothetical protein complement(2577146..2577310) Escherichia coli O157:H7 str. EC4115 6967119 YP_002271090.1 CDS ECH74115_2756 NC_011353.1 2577465 2578175 D tir-cytoskeleton coupling protein 2577465..2578175 Escherichia coli O157:H7 str. EC4115 6967786 YP_002271091.1 CDS ECH74115_2757 NC_011353.1 2578301 2578570 R identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein complement(2578301..2578570) Escherichia coli O157:H7 str. EC4115 6967396 YP_002271092.1 CDS ECH74115_2758 NC_011353.1 2578572 2579891 R identified by match to protein family HMM PF01391; match to protein family HMM PF06820; tail fiber protein complement(2578572..2579891) Escherichia coli O157:H7 str. EC4115 6970895 YP_002271093.1 CDS ECH74115_2759 NC_011353.1 2579198 2579662 D hypothetical protein 2579198..2579662 Escherichia coli O157:H7 str. EC4115 6971736 YP_002271094.1 CDS ECH74115_2760 NC_011353.1 2579821 2579949 D hypothetical protein 2579821..2579949 Escherichia coli O157:H7 str. EC4115 6969616 YP_002271095.1 CDS ECH74115_2761 NC_011353.1 2579950 2580549 R identified by match to protein family HMM PF06316; Ail/Lom family protein complement(2579950..2580549) Escherichia coli O157:H7 str. EC4115 6970639 YP_002271096.1 CDS ECH74115_2762 NC_011353.1 2580617 2584096 R identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein complement(2580617..2584096) Escherichia coli O157:H7 str. EC4115 6968579 YP_002271097.1 CDS ECH74115_2763 NC_011353.1 2584172 2584291 R identified by glimmer; hypothetical protein complement(2584172..2584291) Escherichia coli O157:H7 str. EC4115 6970041 YP_002271098.1 CDS ECH74115_2764 NC_011353.1 2584337 2584915 R identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I complement(2584337..2584915) Escherichia coli O157:H7 str. EC4115 6970776 YP_002271099.1 CDS ECH74115_2765 NC_011353.1 2584912 2585547 R identified by match to protein family HMM PF00877; tail assembly protein complement(2584912..2585547) Escherichia coli O157:H7 str. EC4115 6971459 YP_002271100.1 CDS ECH74115_2766 NC_011353.1 2585666 2586364 R identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L complement(2585666..2586364) Escherichia coli O157:H7 str. EC4115 6972095 YP_002271101.1 CDS ECH74115_2767 NC_011353.1 2586364 2586693 R identified by match to protein family HMM PF05939; phage minor tail protein complement(2586364..2586693) Escherichia coli O157:H7 str. EC4115 6969878 YP_002271102.1 CDS ECH74115_2768 NC_011353.1 2586690 2589269 R identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein complement(2586690..2589269) Escherichia coli O157:H7 str. EC4115 6970513 YP_002271103.1 CDS ECH74115_2769 NC_011353.1 2589250 2589639 R identified by match to protein family HMM TIGR01715; phage tail assembly protein T complement(2589250..2589639) Escherichia coli O157:H7 str. EC4115 6968259 YP_002271104.1 CDS ECH74115_2770 NC_011353.1 2589690 2590121 R identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G complement(2589690..2590121) Escherichia coli O157:H7 str. EC4115 6968893 YP_002271105.1 CDS ECH74115_2771 NC_011353.1 2590135 2590797 R identified by match to protein family HMM PF02368; major tail protein V complement(2590135..2590797) Escherichia coli O157:H7 str. EC4115 6969224 YP_002271106.1 CDS ECH74115_2772 NC_011353.1 2590857 2591123 R major head protein complement(2590857..2591123) Escherichia coli O157:H7 str. EC4115 6967336 YP_002271107.1 CDS ECH74115_2773 NC_011353.1 2591181 2591528 R identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D complement(2591181..2591528) Escherichia coli O157:H7 str. EC4115 6967503 YP_002271108.1 CDS ECH74115_2774 NC_011353.1 2591565 2593070 R identified by match to protein family HMM PF01343; head-tail preconnector protein GP5 complement(2591565..2593070) Escherichia coli O157:H7 str. EC4115 6966746 YP_002271109.1 CDS ECH74115_2775 NC_011353.1 2593060 2594652 R identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family complement(2593060..2594652) Escherichia coli O157:H7 str. EC4115 6966563 YP_002271110.1 CDS ECH74115_2776 NC_011353.1 2594649 2594855 R identified by match to protein family HMM PF02831; gpW complement(2594649..2594855) Escherichia coli O157:H7 str. EC4115 6968964 YP_002271111.1 CDS ECH74115_2779 NC_011353.1 2596740 2597249 R terminase small subunit complement(2596740..2597249) Escherichia coli O157:H7 str. EC4115 6969837 YP_002271112.1 CDS ECH74115_2780 NC_011353.1 2597704 2597868 D hypothetical protein 2597704..2597868 Escherichia coli O157:H7 str. EC4115 6972171 YP_002271113.1 CDS ECH74115_2781 NC_011353.1 2598267 2598380 D hypothetical protein 2598267..2598380 Escherichia coli O157:H7 str. EC4115 6971009 YP_002271114.1 CDS ECH74115_2782 NC_011353.1 2598506 2598646 R hypothetical protein complement(2598506..2598646) Escherichia coli O157:H7 str. EC4115 6967630 YP_002271115.1 CDS ECH74115_2783 NC_011353.1 2598729 2599196 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(2598729..2599196) Escherichia coli O157:H7 str. EC4115 6970826 YP_002271116.1 CDS ECH74115_2784 NC_011353.1 2599348 2599494 R hypothetical protein complement(2599348..2599494) Escherichia coli O157:H7 str. EC4115 6971657 YP_002271117.1 CDS ECH74115_2785 NC_011353.1 2599686 2600219 R identified by match to protein family HMM PF00959; phage lysozyme complement(2599686..2600219) Escherichia coli O157:H7 str. EC4115 6967107 YP_002271118.1 CDS ECH74115_2786 NC_011353.1 2600270 2600614 R identified by match to protein family HMM PF07041; hypothetical protein complement(2600270..2600614) Escherichia coli O157:H7 str. EC4115 6967895 YP_002271119.1 CDS ECH74115_2787 NC_011353.1 2600619 2600825 R identified by match to protein family HMM PF04971; hypothetical protein complement(2600619..2600825) Escherichia coli O157:H7 str. EC4115 6968603 YP_002271120.1 CDS ECH74115_2788 NC_011353.1 2601145 2601471 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2601145..2601471 Escherichia coli O157:H7 str. EC4115 6969176 YP_002271121.1 CDS ECH74115_2789 NC_011353.1 2601468 2602358 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2601468..2602358 Escherichia coli O157:H7 str. EC4115 6967892 YP_002271122.1 CDS ECH74115_2790 NC_011353.1 2602440 2604290 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(2602440..2604290) Escherichia coli O157:H7 str. EC4115 6968329 YP_002271123.1 CDS ECH74115_2792 NC_011353.1 2604604 2604771 R hypothetical protein complement(2604604..2604771) Escherichia coli O157:H7 str. EC4115 6968863 YP_002271124.1 CDS ECH74115_2797 NC_011353.1 2605677 2605799 R identified by glimmer; hypothetical protein complement(2605677..2605799) Escherichia coli O157:H7 str. EC4115 6972338 YP_002271125.1 CDS ECH74115_2798 NC_011353.1 2605830 2606519 R identified by match to protein family HMM PF06323; antitermination protein Q complement(2605830..2606519) Escherichia coli O157:H7 str. EC4115 6966585 YP_002271126.1 CDS ECH74115_2799 NC_011353.1 2606516 2606875 R identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease complement(2606516..2606875) Escherichia coli O157:H7 str. EC4115 6969983 YP_002271127.1 CDS ECH74115_2800 NC_011353.1 2606888 2607937 R identified by match to protein family HMM PF06914; hypothetical protein complement(2606888..2607937) Escherichia coli O157:H7 str. EC4115 6972058 YP_002271128.1 CDS ECH74115_2801 NC_011353.1 2607939 2608298 R hypothetical protein complement(2607939..2608298) Escherichia coli O157:H7 str. EC4115 6970629 YP_002271129.1 CDS ECH74115_2802 NC_011353.1 2608784 2608933 R hypothetical protein complement(2608784..2608933) Escherichia coli O157:H7 str. EC4115 6969799 YP_002271130.1 CDS ECH74115_2803 NC_011353.1 2608998 2609561 R hypothetical protein complement(2608998..2609561) Escherichia coli O157:H7 str. EC4115 6968985 YP_002271131.1 CDS ECH74115_2804 NC_011353.1 2609688 2609999 R hypothetical protein complement(2609688..2609999) Escherichia coli O157:H7 str. EC4115 6968167 YP_002271132.1 CDS ECH74115_2805 NC_011353.1 2610181 2610537 R hypothetical protein complement(2610181..2610537) Escherichia coli O157:H7 str. EC4115 6970892 YP_002271133.1 CDS ECH74115_2806 NC_011353.1 2610780 2611478 R identified by match to protein family HMM PF07789; hypothetical protein complement(2610780..2611478) Escherichia coli O157:H7 str. EC4115 6968693 YP_002271134.1 CDS ECH74115_2807 NC_011353.1 2611513 2611935 R hypothetical protein complement(2611513..2611935) Escherichia coli O157:H7 str. EC4115 6966915 YP_002271135.1 CDS ECH74115_2808 NC_011353.1 2611967 2613004 R hypothetical protein complement(2611967..2613004) Escherichia coli O157:H7 str. EC4115 6967688 YP_002271136.1 CDS ECH74115_2809 NC_011353.1 2613073 2613498 R identified by match to protein family HMM PF06254; hypothetical protein complement(2613073..2613498) Escherichia coli O157:H7 str. EC4115 6968499 YP_002271137.1 CDS ECH74115_2810 NC_011353.1 2613805 2614464 D identified by match to protein family HMM PF00717; repressor protein 2613805..2614464 Escherichia coli O157:H7 str. EC4115 6969372 YP_002271138.1 CDS ECH74115_2811 NC_011353.1 2614739 2614891 D identified by match to protein family HMM PF07151; hypothetical protein 2614739..2614891 Escherichia coli O157:H7 str. EC4115 6971557 YP_002271139.1 CDS ECH74115_2813 NC_011353.1 2615372 2615560 D identified by match to protein family HMM PF05358; hypothetical protein 2615372..2615560 Escherichia coli O157:H7 str. EC4115 6967431 YP_002271140.1 CDS ECH74115_2814 NC_011353.1 2615557 2615745 D identified by match to protein family HMM PF07358; hypothetical protein 2615557..2615745 Escherichia coli O157:H7 str. EC4115 6971125 YP_002271141.1 CDS ECH74115_2815 NC_011353.1 2615841 2618312 D exonuclease family protein 2615841..2618312 Escherichia coli O157:H7 str. EC4115 6968054 YP_002271142.1 CDS ECH74115_2816 NC_011353.1 2618371 2618574 D hypothetical protein 2618371..2618574 Escherichia coli O157:H7 str. EC4115 6966652 YP_002271143.1 CDS ECH74115_2817 NC_011353.1 2618574 2619653 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 2618574..2619653 Escherichia coli O157:H7 str. EC4115 6970349 YP_002271144.1 CDS mtfA NC_011353.1 2619845 2620642 D identified by match to protein family HMM PF06167; Mlc titration factor MtfA 2619845..2620642 Escherichia coli O157:H7 str. EC4115 6972425 YP_002271145.1 CDS ECH74115_2821 NC_011353.1 2621252 2629114 D identified by match to protein family HMM PF02369; hypothetical protein 2621252..2629114 Escherichia coli O157:H7 str. EC4115 6972374 YP_002271146.1 CDS ECH74115_2822 NC_011353.1 2629376 2630428 R hypothetical protein complement(2629376..2630428) Escherichia coli O157:H7 str. EC4115 6969747 YP_002271147.1 CDS shiA NC_011353.1 2630742 2632058 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; shikimate transporter 2630742..2632058 Escherichia coli O157:H7 str. EC4115 6970221 YP_002271148.1 CDS amn NC_011353.1 2632160 2633614 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2632160..2633614 Escherichia coli O157:H7 str. EC4115 6971044 YP_002271149.1 CDS ECH74115_2825 NC_011353.1 2633957 2634673 D identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 2633957..2634673 Escherichia coli O157:H7 str. EC4115 6969302 YP_002271150.1 CDS ECH74115_2826 NC_011353.1 2634764 2634886 R identified by glimmer; hypothetical protein complement(2634764..2634886) Escherichia coli O157:H7 str. EC4115 6970106 YP_002271151.1 CDS ECH74115_2827 NC_011353.1 2634967 2635083 D identified by glimmer; hypothetical protein 2634967..2635083 Escherichia coli O157:H7 str. EC4115 6967662 YP_002271152.1 CDS ECH74115_2829 NC_011353.1 2635299 2636753 R identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; hypothetical protein complement(2635299..2636753) Escherichia coli O157:H7 str. EC4115 6972388 YP_002271153.1 CDS cbl NC_011353.1 2637060 2638010 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2637060..2638010) Escherichia coli O157:H7 str. EC4115 6972432 YP_002271154.1 CDS nac NC_011353.1 2638112 2639029 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2638112..2639029) Escherichia coli O157:H7 str. EC4115 6967246 YP_002271155.1 CDS ECH74115_2833 NC_011353.1 2639217 2639333 D identified by glimmer; hypothetical protein 2639217..2639333 Escherichia coli O157:H7 str. EC4115 6969654 YP_002271156.1 CDS ECH74115_2835 NC_011353.1 2639486 2640421 R identified by match to protein family HMM PF03734; hypothetical protein complement(2639486..2640421) Escherichia coli O157:H7 str. EC4115 6972402 YP_002271157.1 CDS cobT NC_011353.1 2640483 2641562 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2640483..2641562) Escherichia coli O157:H7 str. EC4115 6972074 YP_002271158.1 CDS cobS NC_011353.1 2641574 2642317 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2641574..2642317) Escherichia coli O157:H7 str. EC4115 6971414 YP_002271159.1 CDS ECH74115_2840 NC_011353.1 2643597 2643944 D identified by match to protein family HMM PF05717; IS66 family element, orf2 2643597..2643944 Escherichia coli O157:H7 str. EC4115 6968862 YP_002271160.1 CDS ECH74115_2841 NC_011353.1 2643994 2645532 D identified by match to protein family HMM PF03050; IS66 family element, transposase 2643994..2645532 Escherichia coli O157:H7 str. EC4115 6971629 YP_002271161.1 CDS ECH74115_2842 NC_011353.1 2645773 2645937 R hypothetical protein complement(2645773..2645937) Escherichia coli O157:H7 str. EC4115 6967242 YP_002271162.1 CDS ECH74115_2843 NC_011353.1 2646350 2647240 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(2646350..2647240) Escherichia coli O157:H7 str. EC4115 6968749 YP_002271163.1 CDS ECH74115_2844 NC_011353.1 2647237 2647563 R overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA complement(2647237..2647563) Escherichia coli O157:H7 str. EC4115 6970990 YP_002271164.1 CDS ECH74115_2845 NC_011353.1 2648293 2650440 D identified by match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor 2648293..2650440 Escherichia coli O157:H7 str. EC4115 6967505 YP_002271165.1 CDS ECH74115_2846 NC_011353.1 2650440 2650556 D identified by glimmer; hypothetical protein 2650440..2650556 Escherichia coli O157:H7 str. EC4115 6971930 YP_002271166.1 CDS ECH74115_2847 NC_011353.1 2650893 2651576 D hypothetical protein 2650893..2651576 Escherichia coli O157:H7 str. EC4115 6971297 YP_002271167.1 CDS ECH74115_2848 NC_011353.1 2651573 2652478 D hypothetical protein 2651573..2652478 Escherichia coli O157:H7 str. EC4115 6970651 YP_002271168.1 CDS ECH74115_2849 NC_011353.1 2652487 2653545 D identified by match to protein family HMM PF01734; phospholipase, patatin family 2652487..2653545 Escherichia coli O157:H7 str. EC4115 6970027 YP_002271169.1 CDS ECH74115_2850 NC_011353.1 2653681 2654364 D identified by glimmer; hypothetical protein 2653681..2654364 Escherichia coli O157:H7 str. EC4115 6967388 YP_002271170.1 CDS ECH74115_2852 NC_011353.1 2654380 2654790 D identified by glimmer; hypothetical protein 2654380..2654790 Escherichia coli O157:H7 str. EC4115 6970059 YP_002271171.1 CDS ECH74115_2851 NC_011353.1 2654787 2654921 R identified by glimmer; hypothetical protein complement(2654787..2654921) Escherichia coli O157:H7 str. EC4115 6966854 YP_002271172.1 CDS ECH74115_2853 NC_011353.1 2655011 2655832 D identified by match to protein family HMM PF06067; hypothetical protein 2655011..2655832 Escherichia coli O157:H7 str. EC4115 6971953 YP_002271173.1 CDS ECH74115_2854 NC_011353.1 2655914 2656393 D identified by match to protein family HMM PF03230; antirestriction protein 2655914..2656393 Escherichia coli O157:H7 str. EC4115 6970312 YP_002271174.1 CDS ECH74115_2855 NC_011353.1 2656408 2656884 D identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; DNA repair protein, RadC family 2656408..2656884 Escherichia coli O157:H7 str. EC4115 6970913 YP_002271175.1 CDS ECH74115_2856 NC_011353.1 2656947 2657168 D identified by match to protein family HMM PF06174; hypothetical protein 2656947..2657168 Escherichia coli O157:H7 str. EC4115 6968662 YP_002271176.1 CDS ECH74115_2857 NC_011353.1 2657362 2657610 D identified by match to protein family HMM PF06154; YagB/YeeU/YfjZ family protein 2657362..2657610 Escherichia coli O157:H7 str. EC4115 6969262 YP_002271177.1 CDS ECH74115_2859 NC_011353.1 2658069 2658263 D hypothetical protein 2658069..2658263 Escherichia coli O157:H7 str. EC4115 6967620 YP_002271178.1 CDS ECH74115_2861 NC_011353.1 2658941 2659060 D hypothetical protein 2658941..2659060 Escherichia coli O157:H7 str. EC4115 6968305 YP_002271179.1 CDS ECH74115_2862 NC_011353.1 2659161 2659490 R identified by match to protein family HMM PF04363; hypothetical protein complement(2659161..2659490) Escherichia coli O157:H7 str. EC4115 6967733 YP_002271180.1 CDS ECH74115_2864 NC_011353.1 2659581 2659697 D identified by glimmer; hypothetical protein 2659581..2659697 Escherichia coli O157:H7 str. EC4115 6967480 YP_002271181.1 CDS ECH74115_2863 NC_011353.1 2659662 2660720 R hypothetical protein complement(2659662..2660720) Escherichia coli O157:H7 str. EC4115 6971632 YP_002271182.1 CDS gyrI NC_011353.1 2660919 2661392 R identified by match to protein family HMM PF06445; DNA gyrase inhibitor complement(2660919..2661392) Escherichia coli O157:H7 str. EC4115 6969737 YP_002271183.1 CDS dacD NC_011353.1 2661511 2662683 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2661511..2662683) Escherichia coli O157:H7 str. EC4115 6966754 YP_002271184.1 CDS ECH74115_2867 NC_011353.1 2662604 2662762 D identified by glimmer; hypothetical protein 2662604..2662762 Escherichia coli O157:H7 str. EC4115 6968888 YP_002271185.1 CDS ECH74115_2868 NC_011353.1 2664001 2664651 D identified by match to protein family HMM PF06416; hypothetical protein 2664001..2664651 Escherichia coli O157:H7 str. EC4115 6970830 YP_002271186.1 CDS ECH74115_2869 NC_011353.1 2664875 2665750 R hypothetical protein complement(2664875..2665750) Escherichia coli O157:H7 str. EC4115 6967369 YP_002271187.1 CDS ECH74115_2870 NC_011353.1 2665891 2666160 R identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein complement(2665891..2666160) Escherichia coli O157:H7 str. EC4115 6972153 YP_002271188.1 CDS ECH74115_2871 NC_011353.1 2666162 2667475 R identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein complement(2666162..2667475) Escherichia coli O157:H7 str. EC4115 6968461 YP_002271189.1 CDS ECH74115_2872 NC_011353.1 2667540 2668139 R identified by match to protein family HMM PF06316; Ail/Lom family protein complement(2667540..2668139) Escherichia coli O157:H7 str. EC4115 6967759 YP_002271190.1 CDS ECH74115_2873 NC_011353.1 2668207 2671686 R identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein complement(2668207..2671686) Escherichia coli O157:H7 str. EC4115 6967166 YP_002271191.1 CDS ECH74115_2874 NC_011353.1 2671691 2671816 R identified by glimmer; hypothetical protein complement(2671691..2671816) Escherichia coli O157:H7 str. EC4115 6971059 YP_002271192.1 CDS ECH74115_2875 NC_011353.1 2671925 2672506 R identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I complement(2671925..2672506) Escherichia coli O157:H7 str. EC4115 6967361 YP_002271193.1 CDS ECH74115_2876 NC_011353.1 2672503 2673240 R identified by match to protein family HMM PF00877; tail assembly protein complement(2672503..2673240) Escherichia coli O157:H7 str. EC4115 6968208 YP_002271194.1 CDS ECH74115_2877 NC_011353.1 2673295 2674299 R antirepressor protein complement(2673295..2674299) Escherichia coli O157:H7 str. EC4115 6970259 YP_002271195.1 CDS ECH74115_2878 NC_011353.1 2674289 2674462 R identified by glimmer; hypothetical protein complement(2674289..2674462) Escherichia coli O157:H7 str. EC4115 6966993 YP_002271196.1 CDS ECH74115_2879 NC_011353.1 2674672 2674890 D transcriptional regulator 2674672..2674890 Escherichia coli O157:H7 str. EC4115 6969037 YP_002271197.1 CDS ECH74115_2882 NC_011353.1 2675633 2675974 R identified by match to protein family HMM PF05939; phage minor tail protein complement(2675633..2675974) Escherichia coli O157:H7 str. EC4115 6967391 YP_002271198.1 CDS ECH74115_2883 NC_011353.1 2675967 2679209 R identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein complement(2675967..2679209) Escherichia coli O157:H7 str. EC4115 6967827 YP_002271199.1 CDS ECH74115_2884 NC_011353.1 2679261 2679464 R identified by glimmer; hypothetical protein complement(2679261..2679464) Escherichia coli O157:H7 str. EC4115 6971659 YP_002271200.1 CDS ECH74115_2885 NC_011353.1 2679566 2679940 R identified by match to protein family HMM PF06222; phage tail assembly chaperone complement(2679566..2679940) Escherichia coli O157:H7 str. EC4115 6969434 YP_002271201.1 CDS ECH74115_2886 NC_011353.1 2679946 2680662 R identified by match to protein family HMM PF07679; major tail protein complement(2679946..2680662) Escherichia coli O157:H7 str. EC4115 6970390 YP_002271202.1 CDS ECH74115_2887 NC_011353.1 2680721 2681065 R identified by glimmer; hypothetical protein complement(2680721..2681065) Escherichia coli O157:H7 str. EC4115 6968174 YP_002271203.1 CDS ECH74115_2888 NC_011353.1 2681062 2681508 R identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family complement(2681062..2681508) Escherichia coli O157:H7 str. EC4115 6969277 YP_002271204.1 CDS ECH74115_2889 NC_011353.1 2681505 2681855 R identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor complement(2681505..2681855) Escherichia coli O157:H7 str. EC4115 6967069 YP_002271205.1 CDS ECH74115_2890 NC_011353.1 2681865 2682191 R hypothetical protein complement(2681865..2682191) Escherichia coli O157:H7 str. EC4115 6970962 YP_002271206.1 CDS ECH74115_2891 NC_011353.1 2682271 2684772 R identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family complement(2682271..2684772) Escherichia coli O157:H7 str. EC4115 6969614 YP_002271207.1 CDS ECH74115_2892 NC_011353.1 2684984 2686921 R identified by match to protein family HMM PF04586; prohead protease complement(2684984..2686921) Escherichia coli O157:H7 str. EC4115 6970218 YP_002271208.1 CDS ECH74115_2893 NC_011353.1 2686985 2688646 R identified by match to protein family HMM PF03354; phage terminase, large subunit complement(2686985..2688646) Escherichia coli O157:H7 str. EC4115 6969404 YP_002271209.1 CDS ECH74115_2894 NC_011353.1 2688643 2689206 R terminase small subunit complement(2688643..2689206) Escherichia coli O157:H7 str. EC4115 6971807 YP_002271210.1 CDS ECH74115_2895 NC_011353.1 2689498 2689863 R identified by match to protein family HMM PF01844; HNH endonuclease complement(2689498..2689863) Escherichia coli O157:H7 str. EC4115 6971067 YP_002271211.1 CDS ECH74115_2896 NC_011353.1 2689965 2690132 D hypothetical protein 2689965..2690132 Escherichia coli O157:H7 str. EC4115 6967699 YP_002271212.1 CDS ECH74115_2897 NC_011353.1 2690595 2690777 R bacteriophage protein complement(2690595..2690777) Escherichia coli O157:H7 str. EC4115 6967201 YP_002271213.1 CDS ECH74115_2898 NC_011353.1 2690849 2691346 R identified by match to protein family HMM PF04383; KilA-N domain-containing protein complement(2690849..2691346) Escherichia coli O157:H7 str. EC4115 6969250 YP_002271214.1 CDS ECH74115_2899 NC_011353.1 2691549 2691986 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(2691549..2691986) Escherichia coli O157:H7 str. EC4115 6968843 YP_002271215.1 CDS ECH74115_2900 NC_011353.1 2691983 2692480 R identified by match to protein family HMM PF00959; phage lysozyme complement(2691983..2692480) Escherichia coli O157:H7 str. EC4115 6967975 YP_002271216.1 CDS ECH74115_2901 NC_011353.1 2692480 2692695 R identified by match to protein family HMM PF04971; hypothetical protein complement(2692480..2692695) Escherichia coli O157:H7 str. EC4115 6969086 YP_002271217.1 CDS ECH74115_2902 NC_011353.1 2692772 2693044 R identified by match to protein family HMM PF05696; hypothetical protein complement(2692772..2693044) Escherichia coli O157:H7 str. EC4115 6967090 YP_002271218.1 CDS ECH74115_2903 NC_011353.1 2693085 2693264 R identified by match to protein family HMM PF07125; hypothetical protein complement(2693085..2693264) Escherichia coli O157:H7 str. EC4115 6971055 YP_002271219.1 CDS ECH74115_2904 NC_011353.1 2693401 2695338 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(2693401..2695338) Escherichia coli O157:H7 str. EC4115 6971326 YP_002271220.1 CDS ECH74115_2905 NC_011353.1 2696202 2696471 R identified by match to protein family HMM PF02258; shigatoxin 2, subunit B complement(2696202..2696471) Escherichia coli O157:H7 str. EC4115 6969394 YP_002271221.1 CDS ECH74115_2906 NC_011353.1 2696483 2697442 R identified by match to protein family HMM PF00161; shiga toxin subunit A complement(2696483..2697442) Escherichia coli O157:H7 str. EC4115 6970403 YP_002271222.1 CDS ECH74115_2910 NC_011353.1 2698092 2698580 R identified by match to protein family HMM PF06530; late antiterminator complement(2698092..2698580) Escherichia coli O157:H7 str. EC4115 6972413 YP_002271223.1 CDS ECH74115_2911 NC_011353.1 2698571 2699242 R identified by match to protein family HMM PF00149; serine/threonine-protein phosphatase 1 complement(2698571..2699242) Escherichia coli O157:H7 str. EC4115 6969353 YP_002271224.1 CDS ECH74115_2912 NC_011353.1 2699239 2699844 R identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein complement(2699239..2699844) Escherichia coli O157:H7 str. EC4115 6966933 YP_002271225.1 CDS ECH74115_2913 NC_011353.1 2699844 2700566 R identified by match to protein family HMM PF03374; Roi protein complement(2699844..2700566) Escherichia coli O157:H7 str. EC4115 6967706 YP_002271226.1 CDS ECH74115_2914 NC_011353.1 2700641 2701321 R open reading frame complement(2700641..2701321) Escherichia coli O157:H7 str. EC4115 6971361 YP_002271227.1 CDS ECH74115_2915 NC_011353.1 2701577 2702335 R open reading frame complement(2701577..2702335) Escherichia coli O157:H7 str. EC4115 6972172 YP_002271228.1 CDS ECH74115_2916 NC_011353.1 2702789 2703316 R identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712; phage N-6-adenine-methyltransferase complement(2702789..2703316) Escherichia coli O157:H7 str. EC4115 6968781 YP_002271229.1 CDS ECH74115_2917 NC_011353.1 2703313 2703759 R identified by match to protein family HMM PF05772; protein NinB complement(2703313..2703759) Escherichia coli O157:H7 str. EC4115 6966780 YP_002271230.1 CDS ECH74115_2918 NC_011353.1 2703716 2704078 R identified by match to protein family HMM TIGR03655; restriction alleviation protein, Lar family complement(2703716..2704078) Escherichia coli O157:H7 str. EC4115 6969818 YP_002271231.1 CDS ECH74115_2919 NC_011353.1 2704311 2704589 R hypothetical protein complement(2704311..2704589) Escherichia coli O157:H7 str. EC4115 6970616 YP_002271232.1 CDS ECH74115_2920 NC_011353.1 2704660 2706036 R identified by match to protein family HMM PF00772; match to protein family HMM PF03796; replicative DNA helicase complement(2704660..2706036) Escherichia coli O157:H7 str. EC4115 6972000 YP_002271233.1 CDS ECH74115_2921 NC_011353.1 2706033 2706854 R identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; replication of DNA complement(2706033..2706854) Escherichia coli O157:H7 str. EC4115 6969916 YP_002271234.1 CDS ECH74115_2922 NC_011353.1 2706841 2707002 R hypothetical protein complement(2706841..2707002) Escherichia coli O157:H7 str. EC4115 6967596 YP_002271235.1 CDS ECH74115_2923 NC_011353.1 2707035 2707331 R identified by match to protein family HMM PF05269; bacteriophage CII protein complement(2707035..2707331) Escherichia coli O157:H7 str. EC4115 6971049 YP_002271236.1 CDS ECH74115_2924 NC_011353.1 2707764 2708459 D identified by match to protein family HMM PF00717; match to protein family HMM PF01381; repressor protein 2707764..2708459 Escherichia coli O157:H7 str. EC4115 6970950 YP_002271237.1 CDS ECH74115_2925 NC_011353.1 2708604 2708738 D identified by glimmer; hypothetical protein 2708604..2708738 Escherichia coli O157:H7 str. EC4115 6971706 YP_002271238.1 CDS ECH74115_2926 NC_011353.1 2709102 2709482 D hypothetical protein 2709102..2709482 Escherichia coli O157:H7 str. EC4115 6967780 YP_002271239.1 CDS ECH74115_2927 NC_011353.1 2710542 2710793 D identified by glimmer; hypothetical protein 2710542..2710793 Escherichia coli O157:H7 str. EC4115 6968744 YP_002271240.1 CDS ECH74115_2928 NC_011353.1 2710976 2711344 D identified by glimmer; hypothetical protein 2710976..2711344 Escherichia coli O157:H7 str. EC4115 6969033 YP_002271241.1 CDS ECH74115_2929 NC_011353.1 2711550 2711693 D identified by match to protein family HMM PF06301; kil 2711550..2711693 Escherichia coli O157:H7 str. EC4115 6968562 YP_002271242.1 CDS gam NC_011353.1 2711768 2712064 D identified by match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 2711768..2712064 Escherichia coli O157:H7 str. EC4115 6969675 YP_002271243.1 CDS bet NC_011353.1 2712070 2712855 D identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 2712070..2712855 Escherichia coli O157:H7 str. EC4115 6971902 YP_002271244.1 CDS ECH74115_2932 NC_011353.1 2713150 2714040 R overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB complement(2713150..2714040) Escherichia coli O157:H7 str. EC4115 6970940 YP_002271245.1 CDS ECH74115_2933 NC_011353.1 2714037 2714363 R overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA complement(2714037..2714363) Escherichia coli O157:H7 str. EC4115 6967296 YP_002271246.1 CDS ECH74115_2934 NC_011353.1 2714456 2714845 D exonuclease 2714456..2714845 Escherichia coli O157:H7 str. EC4115 6968790 YP_002271247.1 CDS ECH74115_2935 NC_011353.1 2715075 2715188 D hypothetical protein 2715075..2715188 Escherichia coli O157:H7 str. EC4115 6969948 YP_002271248.1 CDS ECH74115_2936 NC_011353.1 2715265 2715480 D hypothetical protein 2715265..2715480 Escherichia coli O157:H7 str. EC4115 6968273 YP_002271249.1 CDS ECH74115_2937 NC_011353.1 2715797 2716744 D identified by match to protein family HMM PF04447; hypothetical protein 2715797..2716744 Escherichia coli O157:H7 str. EC4115 6967308 YP_002271250.1 CDS ECH74115_2940 NC_011353.1 2717609 2717959 D hypothetical protein 2717609..2717959 Escherichia coli O157:H7 str. EC4115 6970488 YP_002271251.1 CDS ECH74115_2941 NC_011353.1 2718147 2718491 D lipoprotein 2718147..2718491 Escherichia coli O157:H7 str. EC4115 6970007 YP_002271252.1 CDS ECH74115_2943 NC_011353.1 2718569 2718760 D identified by match to protein family HMM PF05930; transcriptional regulator, AlpA family 2718569..2718760 Escherichia coli O157:H7 str. EC4115 6966739 YP_002271253.1 CDS ECH74115_2942 NC_011353.1 2718741 2719919 R identified by match to protein family HMM PF00589; phage integrase family protein complement(2718741..2719919) Escherichia coli O157:H7 str. EC4115 6968413 YP_002271254.1 CDS sbcB NC_011353.1 2720101 2721525 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2720101..2721525 Escherichia coli O157:H7 str. EC4115 6971313 YP_002271255.1 CDS ECH74115_2945 NC_011353.1 2721568 2721795 R identified by match to protein family HMM PF01206; hypothetical protein complement(2721568..2721795) Escherichia coli O157:H7 str. EC4115 6969571 YP_002271256.1 CDS ECH74115_2946 NC_011353.1 2721809 2722867 R identified by match to protein family HMM PF04143; membrane protein, YeeE/YedE family complement(2721809..2722867) Escherichia coli O157:H7 str. EC4115 6971729 YP_002271257.1 CDS yeeF NC_011353.1 2723046 2724404 R identified by match to protein family HMM PF00324; amino acid permease complement(2723046..2724404) Escherichia coli O157:H7 str. EC4115 6966684 YP_002271258.1 CDS ECH74115_2949 NC_011353.1 2724671 2725600 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2724671..2725600) Escherichia coli O157:H7 str. EC4115 6970872 YP_002271259.1 CDS ECH74115_2950 NC_011353.1 2725646 2726470 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase family protein complement(2725646..2726470) Escherichia coli O157:H7 str. EC4115 6969463 YP_002271260.1 CDS hisG NC_011353.1 2727092 2727991 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2727092..2727991 Escherichia coli O157:H7 str. EC4115 6969917 YP_002271261.1 CDS hisD NC_011353.1 2727997 2729301 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2727997..2729301 Escherichia coli O157:H7 str. EC4115 6967860 YP_002271262.1 CDS hisC NC_011353.1 2729298 2730368 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2729298..2730368 Escherichia coli O157:H7 str. EC4115 6968328 YP_002271263.1 CDS hisB NC_011353.1 2730368 2731435 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2730368..2731435 Escherichia coli O157:H7 str. EC4115 6967220 YP_002271264.1 CDS hisH NC_011353.1 2731435 2732025 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2731435..2732025 Escherichia coli O157:H7 str. EC4115 6971949 YP_002271265.1 CDS hisA NC_011353.1 2732025 2732762 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2732025..2732762 Escherichia coli O157:H7 str. EC4115 6966991 YP_002271266.1 CDS hisF NC_011353.1 2732744 2733520 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2732744..2733520 Escherichia coli O157:H7 str. EC4115 6972148 YP_002271267.1 CDS hisIE NC_011353.1 2733514 2734125 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2733514..2734125 Escherichia coli O157:H7 str. EC4115 6968882 YP_002271268.1 CDS ECH74115_2960 NC_011353.1 2734222 2735199 R identified by match to protein family HMM PF02706; chain length determinant protein complement(2734222..2735199) Escherichia coli O157:H7 str. EC4115 6968047 YP_002271269.1 CDS ugd NC_011353.1 2735345 2736511 R identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase complement(2735345..2736511) Escherichia coli O157:H7 str. EC4115 6970139 YP_002271270.1 CDS gnd NC_011353.1 2736760 2738166 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2736760..2738166) Escherichia coli O157:H7 str. EC4115 6970053 YP_002271271.1 CDS ECH74115_2963 NC_011353.1 2739924 2740037 D identified by glimmer; hypothetical protein 2739924..2740037 Escherichia coli O157:H7 str. EC4115 6972103 YP_002271272.1 CDS ECH74115_2964 NC_011353.1 2740295 2741665 R identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase complement(2740295..2741665) Escherichia coli O157:H7 str. EC4115 6971241 YP_002271273.1 CDS ECH74115_2965 NC_011353.1 2741669 2743117 R identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase complement(2741669..2743117) Escherichia coli O157:H7 str. EC4115 6968492 YP_002271274.1 CDS ECH74115_2966 NC_011353.1 2743099 2743608 R identified by match to protein family HMM PF00293; GDP-mannose mannosyl hydrolase complement(2743099..2743608) Escherichia coli O157:H7 str. EC4115 6969300 YP_002271275.1 CDS ECH74115_2967 NC_011353.1 2743611 2744576 R identified by match to protein family HMM PF01370; GDP-L-fucose synthetase complement(2743611..2744576) Escherichia coli O157:H7 str. EC4115 6968505 YP_002271276.1 CDS gmd NC_011353.1 2744579 2745697 R identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase complement(2744579..2745697) Escherichia coli O157:H7 str. EC4115 6968025 YP_002271277.1 CDS ECH74115_2969 NC_011353.1 2745717 2746931 R identified by match to protein family HMM PF00534; WbdP complement(2745717..2746931) Escherichia coli O157:H7 str. EC4115 6971548 YP_002271278.1 CDS ECH74115_2970 NC_011353.1 2746956 2748050 R identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS family aminotransferase complement(2746956..2748050) Escherichia coli O157:H7 str. EC4115 6969585 YP_002271279.1 CDS ECH74115_2971 NC_011353.1 2748053 2749438 R identified by match to protein family HMM PF01943; O antigen flippase complement(2748053..2749438) Escherichia coli O157:H7 str. EC4115 6966930 YP_002271280.1 CDS ECH74115_2972 NC_011353.1 2749431 2750177 R WbdO complement(2749431..2750177) Escherichia coli O157:H7 str. EC4115 6971856 YP_002271281.1 CDS ECH74115_2973 NC_011353.1 2750146 2751330 R O antigen polymerase complement(2750146..2751330) Escherichia coli O157:H7 str. EC4115 6968169 YP_002271282.1 CDS ECH74115_2974 NC_011353.1 2751327 2752109 R identified by match to protein family HMM PF00535; WbdN complement(2751327..2752109) Escherichia coli O157:H7 str. EC4115 6967382 YP_002271283.1 CDS galF NC_011353.1 2752428 2753321 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF complement(2752428..2753321) Escherichia coli O157:H7 str. EC4115 6971770 YP_002271284.1 CDS gne NC_011353.1 2753564 2754559 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; UDP-N-acetylglucosamine 4-epimerase complement(2753564..2754559) Escherichia coli O157:H7 str. EC4115 6971182 YP_002271285.1 CDS wcaM NC_011353.1 2754717 2756111 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2754717..2756111) Escherichia coli O157:H7 str. EC4115 6969348 YP_002271286.1 CDS wcaL NC_011353.1 2756122 2757342 R identified by match to protein family HMM PF00534; colanic acid biosynthesis glycosyl transferase WcaL complement(2756122..2757342) Escherichia coli O157:H7 str. EC4115 6968361 YP_002271287.1 CDS wcaK NC_011353.1 2757339 2758619 R identified by match to protein family HMM PF04230; pyruvyl transferase complement(2757339..2758619) Escherichia coli O157:H7 str. EC4115 6970131 YP_002271288.1 CDS wzxC NC_011353.1 2758799 2760277 R identified by match to protein family HMM PF01943; colanic acid exporter complement(2758799..2760277) Escherichia coli O157:H7 str. EC4115 6969998 YP_002271289.1 CDS ECH74115_2981 NC_011353.1 2760279 2761673 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2760279..2761673) Escherichia coli O157:H7 str. EC4115 6969738 YP_002271290.1 CDS cpsG NC_011353.1 2761728 2763098 R identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase complement(2761728..2763098) Escherichia coli O157:H7 str. EC4115 6971636 YP_002271291.1 CDS ECH74115_2983 NC_011353.1 2763124 2763282 D hypothetical protein 2763124..2763282 Escherichia coli O157:H7 str. EC4115 6967629 YP_002271292.1 CDS cpsB NC_011353.1 2763291 2764727 R identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase complement(2763291..2764727) Escherichia coli O157:H7 str. EC4115 6967001 YP_002271293.1 CDS wcaI NC_011353.1 2764730 2765953 R identified by match to protein family HMM PF00534; glycosyl transferase family protein complement(2764730..2765953) Escherichia coli O157:H7 str. EC4115 6967214 YP_002271294.1 CDS nudD NC_011353.1 2765950 2766429 R identified by match to protein family HMM PF00293; GDP-mannose mannosyl hydrolase complement(2765950..2766429) Escherichia coli O157:H7 str. EC4115 6967806 YP_002271295.1 CDS fcl NC_011353.1 2766432 2767397 R identified by match to protein family HMM PF01370; GDP-L-fucose synthetase complement(2766432..2767397) Escherichia coli O157:H7 str. EC4115 6970109 YP_002271296.1 CDS gmd NC_011353.1 2767400 2768521 R identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase complement(2767400..2768521) Escherichia coli O157:H7 str. EC4115 6970756 YP_002271297.1 CDS ECH74115_2989 NC_011353.1 2768550 2769098 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2768550..2769098) Escherichia coli O157:H7 str. EC4115 6971750 YP_002271298.1 CDS wcaE NC_011353.1 2769114 2769860 R identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(2769114..2769860) Escherichia coli O157:H7 str. EC4115 6971991 YP_002271299.1 CDS wcaD NC_011353.1 2769871 2771088 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2769871..2771088) Escherichia coli O157:H7 str. EC4115 6967323 YP_002271300.1 CDS wcaC NC_011353.1 2771063 2772280 R glycosyl transferase family protein complement(2771063..2772280) Escherichia coli O157:H7 str. EC4115 6971076 YP_002271301.1 CDS ECH74115_2993 NC_011353.1 2772277 2772765 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2772277..2772765) Escherichia coli O157:H7 str. EC4115 6969238 YP_002271302.1 CDS wcaA NC_011353.1 2772768 2773607 R identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(2772768..2773607) Escherichia coli O157:H7 str. EC4115 6966594 YP_002271303.1 CDS wzc NC_011353.1 2773700 2775862 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2773700..2775862) Escherichia coli O157:H7 str. EC4115 6966601 YP_002271304.1 CDS wzb NC_011353.1 2775865 2776308 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2775865..2776308) Escherichia coli O157:H7 str. EC4115 6967385 YP_002271305.1 CDS ECH74115_2997 NC_011353.1 2776314 2777453 R identified by match to protein family HMM PF02563; polysaccharide biosynthesis/export protein complement(2776314..2777453) Escherichia coli O157:H7 str. EC4115 6971696 YP_002271306.1 CDS ECH74115_2998 NC_011353.1 2778112 2779695 D identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein 2778112..2779695 Escherichia coli O157:H7 str. EC4115 6969971 YP_002271307.1 CDS ECH74115_2999 NC_011353.1 2779770 2780108 D identified by match to protein family HMM PF05973; hypothetical protein 2779770..2780108 Escherichia coli O157:H7 str. EC4115 6970738 YP_002271308.1 CDS ECH74115_3000 NC_011353.1 2780098 2780388 D identified by match to protein family HMM PF01381; DNA-binding protein 2780098..2780388 Escherichia coli O157:H7 str. EC4115 6968311 YP_002271309.1 CDS asmA NC_011353.1 2780441 2782294 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2780441..2782294) Escherichia coli O157:H7 str. EC4115 6967064 YP_002271310.1 CDS dcd NC_011353.1 2782316 2782897 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2782316..2782897) Escherichia coli O157:H7 str. EC4115 6966814 YP_002271311.1 CDS udk NC_011353.1 2782989 2783630 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2782989..2783630) Escherichia coli O157:H7 str. EC4115 6967463 YP_002271312.1 CDS alkA NC_011353.1 2787367 2788215 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2787367..2788215) Escherichia coli O157:H7 str. EC4115 6971168 YP_002271313.1 CDS ECH74115_3007 NC_011353.1 2788349 2789701 D chaperone 2788349..2789701 Escherichia coli O157:H7 str. EC4115 6972142 YP_002271314.1 CDS ECH74115_3008 NC_011353.1 2789714 2791654 R hypothetical protein complement(2789714..2791654) Escherichia coli O157:H7 str. EC4115 6968785 YP_002271315.1 CDS ECH74115_3009 NC_011353.1 2791651 2792412 R hypothetical protein complement(2791651..2792412) Escherichia coli O157:H7 str. EC4115 6968171 YP_002271316.1 CDS ECH74115_3010 NC_011353.1 2792409 2793068 R identified by match to protein family HMM PF00092; von Willebrand factor type A domain-containing protein complement(2792409..2793068) Escherichia coli O157:H7 str. EC4115 6967168 YP_002271317.1 CDS mdtA NC_011353.1 2794284 2795531 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2794284..2795531 Escherichia coli O157:H7 str. EC4115 6972317 YP_002271318.1 CDS mdtB NC_011353.1 2795531 2798653 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2795531..2798653 Escherichia coli O157:H7 str. EC4115 6971319 YP_002271319.1 CDS mdtC NC_011353.1 2798654 2801731 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2798654..2801731 Escherichia coli O157:H7 str. EC4115 6970687 YP_002271320.1 CDS ECH74115_3017 NC_011353.1 2801732 2803147 D identified by match to protein family HMM PF07690; multidrug efflux system protein MdtE 2801732..2803147 Escherichia coli O157:H7 str. EC4115 6969696 YP_002271321.1 CDS baeS NC_011353.1 2803144 2804547 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; signal transduction histidine-protein kinase BaeS 2803144..2804547 Escherichia coli O157:H7 str. EC4115 6971062 YP_002271322.1 CDS baeR NC_011353.1 2804544 2805266 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2804544..2805266 Escherichia coli O157:H7 str. EC4115 6968999 YP_002271323.1 CDS ECH74115_3020 NC_011353.1 2805457 2805789 D identified by match to protein family HMM PF07411; hypothetical protein 2805457..2805789 Escherichia coli O157:H7 str. EC4115 6969835 YP_002271324.1 CDS ECH74115_3021 NC_011353.1 2805937 2807298 D identified by match to protein family HMM PF01136; U32 family peptidase 2805937..2807298 Escherichia coli O157:H7 str. EC4115 6972250 YP_002271325.1 CDS ECH74115_3023 NC_011353.1 2807572 2807826 R in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator complement(2807572..2807826) Escherichia coli O157:H7 str. EC4115 6972290 YP_002271326.1 CDS ECH74115_3024 NC_011353.1 2807872 2809035 R identified by match to protein family HMM PF05954; phage late control gene D protein complement(2807872..2809035) Escherichia coli O157:H7 str. EC4115 6970611 YP_002271327.1 CDS gpU NC_011353.1 2809035 2809514 R identified by match to protein family HMM PF06995; phage protein gpU complement(2809035..2809514) Escherichia coli O157:H7 str. EC4115 6969960 YP_002271328.1 CDS ECH74115_3026 NC_011353.1 2809529 2811976 R identified by match to protein family HMM TIGR01760; phage tail tape measure protein, TP901 family complement(2809529..2811976) Escherichia coli O157:H7 str. EC4115 6968919 YP_002271329.1 CDS ECH74115_3029 NC_011353.1 2812453 2812971 R identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611; phage major tail tube protein FII complement(2812453..2812971) Escherichia coli O157:H7 str. EC4115 6969575 YP_002271330.1 CDS ECH74115_3030 NC_011353.1 2812984 2814174 R identified by match to protein family HMM PF04984; phage tail sheath protein complement(2812984..2814174) Escherichia coli O157:H7 str. EC4115 6967305 YP_002271331.1 CDS ECH74115_3031 NC_011353.1 2814234 2814827 R identified by match to protein family HMM PF00239; match to protein family HMM PF02796; DNA-invertase complement(2814234..2814827) Escherichia coli O157:H7 str. EC4115 6967950 YP_002271332.1 CDS ECH74115_3032 NC_011353.1 2814858 2815388 D identified by match to protein family HMM PF07484; tail collar domain-containing protein 2814858..2815388 Escherichia coli O157:H7 str. EC4115 6970673 YP_002271333.1 CDS ECH74115_3034 NC_011353.1 2815388 2815990 D identified by match to protein family HMM PF02413; tail fiber assembly protein-like protein 2815388..2815990 Escherichia coli O157:H7 str. EC4115 6971250 YP_002271334.1 CDS ECH74115_3033 NC_011353.1 2815962 2816405 R identified by match to protein family HMM PF02413; tail fiber assembly protein complement(2815962..2816405) Escherichia coli O157:H7 str. EC4115 6968909 YP_002271335.1 CDS ECH74115_3035 NC_011353.1 2816426 2817625 R phage tail collar domain-containing protein complement(2816426..2817625) Escherichia coli O157:H7 str. EC4115 6969184 YP_002271336.1 CDS ECH74115_3036 NC_011353.1 2817622 2818233 R identified by match to protein family HMM PF09684; match to protein family HMM TIGR01634; tail protein I complement(2817622..2818233) Escherichia coli O157:H7 str. EC4115 6966821 YP_002271337.1 CDS ECH74115_3037 NC_011353.1 2818226 2819134 R identified by match to protein family HMM PF04865; baseplate assembly protein GpJ complement(2818226..2819134) Escherichia coli O157:H7 str. EC4115 6967405 YP_002271338.1 CDS ECH74115_3038 NC_011353.1 2819139 2819486 R identified by match to protein family HMM PF04965; baseplate assembly protein GpW complement(2819139..2819486) Escherichia coli O157:H7 str. EC4115 6971436 YP_002271339.1 CDS ECH74115_3039 NC_011353.1 2819483 2820118 R identified by match to protein family HMM PF04717; match to protein family HMM TIGR01644; phage baseplate assembly protein GpV complement(2819483..2820118) Escherichia coli O157:H7 str. EC4115 6967449 YP_002271340.1 CDS ECH74115_3040 NC_011353.1 2820185 2820637 R identified by match to protein family HMM PF05069; match to protein family HMM TIGR01635; phage virion morphogenesis protein GpS complement(2820185..2820637) Escherichia coli O157:H7 str. EC4115 6970770 YP_002271341.1 CDS ECH74115_3041 NC_011353.1 2820630 2821097 R identified by match to protein family HMM PF06891; phage tail completion protein GpR complement(2820630..2821097) Escherichia coli O157:H7 str. EC4115 6971337 YP_002271342.1 CDS ECH74115_3042 NC_011353.1 2821060 2821218 R phage lysis protein complement(2821060..2821218) Escherichia coli O157:H7 str. EC4115 6968018 YP_002271343.1 CDS ECH74115_3043 NC_011353.1 2821205 2821630 R identified by match to protein family HMM TIGR03495; phage lysis timing protein LysB complement(2821205..2821630) Escherichia coli O157:H7 str. EC4115 6968847 YP_002271344.1 CDS ECH74115_3044 NC_011353.1 2821618 2822043 R phage lysis protein LysA complement(2821618..2822043) Escherichia coli O157:H7 str. EC4115 6966758 YP_002271345.1 CDS ECH74115_3045 NC_011353.1 2822058 2822555 R identified by match to protein family HMM PF00959; phage lysozyme complement(2822058..2822555) Escherichia coli O157:H7 str. EC4115 6967587 YP_002271346.1 CDS ECH74115_3046 NC_011353.1 2822555 2822836 R identified by match to protein family HMM PF04550; phage holin GpY complement(2822555..2822836) Escherichia coli O157:H7 str. EC4115 6971287 YP_002271347.1 CDS ECH74115_3047 NC_011353.1 2822840 2823043 R identified by match to protein family HMM PF05489; phage tail protein GpX complement(2822840..2823043) Escherichia coli O157:H7 str. EC4115 6966807 YP_002271348.1 CDS ECH74115_3048 NC_011353.1 2823043 2823516 R identified by match to protein family HMM PF05926; phage head completion protein GPL complement(2823043..2823516) Escherichia coli O157:H7 str. EC4115 6970034 YP_002271349.1 CDS ECH74115_3049 NC_011353.1 2823652 2824395 R identified by match to protein family HMM PF05944; phage small terminase subunit GpM complement(2823652..2824395) Escherichia coli O157:H7 str. EC4115 6969531 YP_002271350.1 CDS ECH74115_3050 NC_011353.1 2824399 2825472 R identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551; phage major capsid protein GpN complement(2824399..2825472) Escherichia coli O157:H7 str. EC4115 6971965 YP_002271351.1 CDS ECH74115_3051 NC_011353.1 2825531 2826385 R identified by match to protein family HMM PF05929; phage capsid scaffolding protein GpO complement(2825531..2826385) Escherichia coli O157:H7 str. EC4115 6971191 YP_002271352.1 CDS ECH74115_3052 NC_011353.1 2826559 2828331 D identified by match to protein family HMM PF03237; match to protein family HMM PF06056; phage large terminase subunit GpP 2826559..2828331 Escherichia coli O157:H7 str. EC4115 6972087 YP_002271353.1 CDS ECH74115_3053 NC_011353.1 2828331 2829365 D identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540; phage portal protein, pbsx family 2828331..2829365 Escherichia coli O157:H7 str. EC4115 6971517 YP_002271354.1 CDS ECH74115_3054 NC_011353.1 2829404 2829565 R identified by glimmer; hypothetical protein complement(2829404..2829565) Escherichia coli O157:H7 str. EC4115 6967979 YP_002271355.1 CDS ECH74115_3055 NC_011353.1 2829683 2831650 R hypothetical protein complement(2829683..2831650) Escherichia coli O157:H7 str. EC4115 6967352 YP_002271356.1 CDS ECH74115_3056 NC_011353.1 2831650 2832102 R identified by glimmer; hypothetical protein complement(2831650..2832102) Escherichia coli O157:H7 str. EC4115 6969873 YP_002271357.1 CDS ECH74115_3057 NC_011353.1 2832149 2833372 R identified by match to protein family HMM PF05057; match to protein family HMM PF07819; hypothetical protein complement(2832149..2833372) Escherichia coli O157:H7 str. EC4115 6968913 YP_002271358.1 CDS ECH74115_3058 NC_011353.1 2833462 2835744 R identified by match to protein family HMM PF05840; bacteriophage replication gene A protein complement(2833462..2835744) Escherichia coli O157:H7 str. EC4115 6971479 YP_002271359.1 CDS ECH74115_3059 NC_011353.1 2835734 2836009 R hypothetical protein complement(2835734..2836009) Escherichia coli O157:H7 str. EC4115 6969859 YP_002271360.1 CDS ECH74115_3060 NC_011353.1 2836006 2836230 R identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; C4-type zinc finger protein, DksA/TraR family complement(2836006..2836230) Escherichia coli O157:H7 str. EC4115 6972078 YP_002271361.1 CDS ECH74115_3061 NC_011353.1 2836233 2836532 R hypothetical protein complement(2836233..2836532) Escherichia coli O157:H7 str. EC4115 6971518 YP_002271362.1 CDS ECH74115_3062 NC_011353.1 2836532 2836756 R hypothetical protein complement(2836532..2836756) Escherichia coli O157:H7 str. EC4115 6968501 YP_002271363.1 CDS ECH74115_3063 NC_011353.1 2836820 2837320 R replication gene B protein complement(2836820..2837320) Escherichia coli O157:H7 str. EC4115 6969123 YP_002271364.1 CDS ECH74115_3064 NC_011353.1 2837317 2837487 R hypothetical protein complement(2837317..2837487) Escherichia coli O157:H7 str. EC4115 6970486 YP_002271365.1 CDS ECH74115_3065 NC_011353.1 2837498 2837683 R Cox protein complement(2837498..2837683) Escherichia coli O157:H7 str. EC4115 6969863 YP_002271366.1 CDS ECH74115_3066 NC_011353.1 2838310 2839323 D identified by match to protein family HMM PF00589; integrase 2838310..2839323 Escherichia coli O157:H7 str. EC4115 6969892 YP_002271367.1 CDS ECH74115_3067 NC_011353.1 2839588 2839920 R hypothetical protein complement(2839588..2839920) Escherichia coli O157:H7 str. EC4115 6972130 YP_002271368.1 CDS ECH74115_3068 NC_011353.1 2840311 2841210 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2840311..2841210 Escherichia coli O157:H7 str. EC4115 6967255 YP_002271369.1 CDS gatR NC_011353.1 2841292 2842071 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; galactitol utilization operon repressor complement(2841292..2842071) Escherichia coli O157:H7 str. EC4115 6967653 YP_002271370.1 CDS gatD NC_011353.1 2842171 2843211 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2842171..2843211) Escherichia coli O157:H7 str. EC4115 6967577 YP_002271371.1 CDS gatC NC_011353.1 2843259 2844614 R identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827; PTS system galactitol-specific transporter subunit IIC complement(2843259..2844614) Escherichia coli O157:H7 str. EC4115 6966799 YP_002271372.1 CDS gatB NC_011353.1 2844618 2844902 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2844618..2844902) Escherichia coli O157:H7 str. EC4115 6968419 YP_002271373.1 CDS gatA NC_011353.1 2844933 2845385 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2844933..2845385) Escherichia coli O157:H7 str. EC4115 6970692 YP_002271374.1 CDS ECH74115_3074 NC_011353.1 2845395 2846657 R identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; tagatose-6-phosphate kinase complement(2845395..2846657) Escherichia coli O157:H7 str. EC4115 6969424 YP_002271375.1 CDS gatY NC_011353.1 2846686 2847540 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2846686..2847540) Escherichia coli O157:H7 str. EC4115 6972197 YP_002271376.1 CDS fbaB NC_011353.1 2847839 2848891 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2847839..2848891) Escherichia coli O157:H7 str. EC4115 6967875 YP_002271377.1 CDS yegT NC_011353.1 2849148 2850425 D identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside transporter 2849148..2850425 Escherichia coli O157:H7 str. EC4115 6967103 YP_002271378.1 CDS ECH74115_3078 NC_011353.1 2850422 2851426 D identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase family protein 2850422..2851426 Escherichia coli O157:H7 str. EC4115 6969155 YP_002271379.1 CDS ECH74115_3080 NC_011353.1 2851423 2852388 D identified by match to protein family HMM PF00294; kinase, PfkB family 2851423..2852388 Escherichia coli O157:H7 str. EC4115 6966642 YP_002271380.1 CDS ECH74115_3079 NC_011353.1 2852362 2853108 R identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator complement(2852362..2853108) Escherichia coli O157:H7 str. EC4115 6968600 YP_002271381.1 CDS ECH74115_3081 NC_011353.1 2853160 2853978 R identified by match to protein family HMM PF01183; glycosyl hydrolase family 25 complement(2853160..2853978) Escherichia coli O157:H7 str. EC4115 6970500 YP_002271382.1 CDS thiD NC_011353.1 2854043 2854843 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2854043..2854843) Escherichia coli O157:H7 str. EC4115 6967677 YP_002271383.1 CDS thiM NC_011353.1 2854840 2855628 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2854840..2855628) Escherichia coli O157:H7 str. EC4115 6971519 YP_002271384.1 CDS ECH74115_3085 NC_011353.1 2856049 2856201 D hypothetical protein 2856049..2856201 Escherichia coli O157:H7 str. EC4115 6966806 YP_002271385.1 CDS ECH74115_3086 NC_011353.1 2857423 2857599 D hypothetical protein 2857423..2857599 Escherichia coli O157:H7 str. EC4115 6966983 YP_002271386.1 CDS ECH74115_3087 NC_011353.1 2857609 2857923 D outer membrane protein 2857609..2857923 Escherichia coli O157:H7 str. EC4115 6968022 YP_002271387.1 CDS ECH74115_3088 NC_011353.1 2858033 2858305 R identified by match to protein family HMM PF02583; transcriptional repressor RcnR complement(2858033..2858305) Escherichia coli O157:H7 str. EC4115 6969018 YP_002271388.1 CDS rcnA NC_011353.1 2858425 2859282 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2858425..2859282 Escherichia coli O157:H7 str. EC4115 6969968 YP_002271389.1 CDS ECH74115_3090 NC_011353.1 2859500 2859838 D hypothetical protein 2859500..2859838 Escherichia coli O157:H7 str. EC4115 6968048 YP_002271390.1 CDS ECH74115_3091 NC_011353.1 2859920 2860954 R type-1 fimbrial protein complement(2859920..2860954) Escherichia coli O157:H7 str. EC4115 6966944 YP_002271391.1 CDS ECH74115_3092 NC_011353.1 2860965 2863445 R identified by match to protein family HMM PF00577; fimbrial usher protein complement(2860965..2863445) Escherichia coli O157:H7 str. EC4115 6967900 YP_002271392.1 CDS ECH74115_3093 NC_011353.1 2863461 2864135 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; gram-negative pilus assembly chaperone complement(2863461..2864135) Escherichia coli O157:H7 str. EC4115 6971634 YP_002271393.1 CDS ECH74115_3094 NC_011353.1 2864223 2864765 R identified by match to protein family HMM PF00419; fimbrial protein complement(2864223..2864765) Escherichia coli O157:H7 str. EC4115 6971016 YP_002271394.1 CDS ECH74115_3095 NC_011353.1 2865057 2865218 R hypothetical protein complement(2865057..2865218) Escherichia coli O157:H7 str. EC4115 6968631 YP_002271395.1 CDS ECH74115_3096 NC_011353.1 2865600 2866709 R ATPase complement(2865600..2866709) Escherichia coli O157:H7 str. EC4115 6969445 YP_002271396.1 CDS metG NC_011353.1 2866841 2868874 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2866841..2868874 Escherichia coli O157:H7 str. EC4115 6969268 YP_002271397.1 CDS ECH74115_3099 NC_011353.1 2869933 2872824 D identified by glimmer; hypothetical protein 2869933..2872824 Escherichia coli O157:H7 str. EC4115 6967527 YP_002271398.1 CDS ECH74115_3102 NC_011353.1 2875832 2879461 D molybdate metabolism regulator MolR-like protein 2875832..2879461 Escherichia coli O157:H7 str. EC4115 6971228 YP_002271399.1 CDS ECH74115_3103 NC_011353.1 2879523 2879840 D identified by glimmer; hypothetical protein 2879523..2879840 Escherichia coli O157:H7 str. EC4115 6971955 YP_002271400.1 CDS ECH74115_3104 NC_011353.1 2880265 2880417 R identified by glimmer; hypothetical protein complement(2880265..2880417) Escherichia coli O157:H7 str. EC4115 6971330 YP_002271401.1 CDS ECH74115_3105 NC_011353.1 2881081 2882169 D identified by match to protein family HMM PF07728; AAA ATPase 2881081..2882169 Escherichia coli O157:H7 str. EC4115 6970719 YP_002271402.1 CDS ECH74115_3108 NC_011353.1 2884452 2885588 D identified by match to protein family HMM PF00092; match to protein family HMM PF05762; von Willebrand factor type A domain-containing protein 2884452..2885588 Escherichia coli O157:H7 str. EC4115 6967339 YP_002271403.1 CDS ECH74115_3109 NC_011353.1 2885585 2887588 D identified by match to protein family HMM PF04434; hypothetical protein 2885585..2887588 Escherichia coli O157:H7 str. EC4115 6966889 YP_002271404.1 CDS ECH74115_3110 NC_011353.1 2887713 2888174 D identified by match to protein family HMM PF06998; lipoprotein 2887713..2888174 Escherichia coli O157:H7 str. EC4115 6968664 YP_002271405.1 CDS ECH74115_3111 NC_011353.1 2888216 2888686 R identified by match to protein family HMM PF07308; hypothetical protein complement(2888216..2888686) Escherichia coli O157:H7 str. EC4115 6967850 YP_002271406.1 CDS ECH74115_3112 NC_011353.1 2888733 2889452 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2888733..2889452) Escherichia coli O157:H7 str. EC4115 6967617 YP_002271407.1 CDS ECH74115_3113 NC_011353.1 2889449 2891134 R identified by match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase complement(2889449..2891134) Escherichia coli O157:H7 str. EC4115 6966817 YP_002271408.1 CDS ECH74115_3114 NC_011353.1 2891223 2891351 D identified by glimmer; hypothetical protein 2891223..2891351 Escherichia coli O157:H7 str. EC4115 6969522 YP_002271409.1 CDS ECH74115_3115 NC_011353.1 2891393 2891533 D identified by glimmer; hypothetical protein 2891393..2891533 Escherichia coli O157:H7 str. EC4115 6970207 YP_002271410.1 CDS ECH74115_3116 NC_011353.1 2891649 2891897 D identified by match to protein family HMM PF06183; hypothetical protein 2891649..2891897 Escherichia coli O157:H7 str. EC4115 6971126 YP_002271411.1 CDS ECH74115_3117 NC_011353.1 2892265 2892534 R identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein complement(2892265..2892534) Escherichia coli O157:H7 str. EC4115 6971773 YP_002271412.1 CDS ECH74115_3118 NC_011353.1 2892536 2893849 R identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein complement(2892536..2893849) Escherichia coli O157:H7 str. EC4115 6966927 YP_002271413.1 CDS ECH74115_3119 NC_011353.1 2893914 2894513 R identified by match to protein family HMM PF06316; Ail/Lom family protein complement(2893914..2894513) Escherichia coli O157:H7 str. EC4115 6966859 YP_002271414.1 CDS ECH74115_3120 NC_011353.1 2894581 2898054 R identified by match to protein family HMM PF09327; hypothetical protein complement(2894581..2898054) Escherichia coli O157:H7 str. EC4115 6971393 YP_002271415.1 CDS ECH74115_3121 NC_011353.1 2898130 2898249 R identified by glimmer; hypothetical protein complement(2898130..2898249) Escherichia coli O157:H7 str. EC4115 6972235 YP_002271416.1 CDS ECH74115_3122 NC_011353.1 2898295 2898873 R identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I complement(2898295..2898873) Escherichia coli O157:H7 str. EC4115 6967111 YP_002271417.1 CDS ECH74115_3123 NC_011353.1 2898870 2899505 R identified by match to protein family HMM PF00877; tail assembly protein complement(2898870..2899505) Escherichia coli O157:H7 str. EC4115 6970960 YP_002271418.1 CDS ECH74115_3124 NC_011353.1 2899624 2900322 R identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L complement(2899624..2900322) Escherichia coli O157:H7 str. EC4115 6968334 YP_002271419.1 CDS ECH74115_3125 NC_011353.1 2900322 2900651 R identified by match to protein family HMM PF05939; phage minor tail protein complement(2900322..2900651) Escherichia coli O157:H7 str. EC4115 6969089 YP_002271420.1 CDS ECH74115_3126 NC_011353.1 2900648 2903293 R identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein complement(2900648..2903293) Escherichia coli O157:H7 str. EC4115 6969619 YP_002271421.1 CDS ECH74115_3127 NC_011353.1 2903337 2903645 R identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T complement(2903337..2903645) Escherichia coli O157:H7 str. EC4115 6970432 YP_002271422.1 CDS ECH74115_3129 NC_011353.1 2904108 2904860 R identified by match to protein family HMM PF02368; major tail protein V complement(2904108..2904860) Escherichia coli O157:H7 str. EC4115 6971528 YP_002271423.1 CDS ECH74115_3130 NC_011353.1 2904868 2905266 R identified by match to protein family HMM PF06141; phage minor tail protein U complement(2904868..2905266) Escherichia coli O157:H7 str. EC4115 6971587 YP_002271424.1 CDS ECH74115_3131 NC_011353.1 2905279 2905902 R identified by match to protein family HMM PF06763; prophage minor tail protein Z complement(2905279..2905902) Escherichia coli O157:H7 str. EC4115 6970955 YP_002271425.1 CDS ECH74115_3132 NC_011353.1 2905905 2906153 R hypothetical protein complement(2905905..2906153) Escherichia coli O157:H7 str. EC4115 6970340 YP_002271426.1 CDS ECH74115_3133 NC_011353.1 2906179 2906505 R membrane protein complement(2906179..2906505) Escherichia coli O157:H7 str. EC4115 6969718 YP_002271427.1 CDS ECH74115_3134 NC_011353.1 2906593 2910063 R identified by match to protein family HMM PF00574; match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family complement(2906593..2910063) Escherichia coli O157:H7 str. EC4115 6969297 YP_002271428.1 CDS ECH74115_3135 NC_011353.1 2910063 2910275 R hypothetical protein complement(2910063..2910275) Escherichia coli O157:H7 str. EC4115 6968625 YP_002271429.1 CDS ECH74115_3136 NC_011353.1 2910272 2912395 R identified by match to protein family HMM PF05876; phage terminase large subunit complement(2910272..2912395) Escherichia coli O157:H7 str. EC4115 6967723 YP_002271430.1 CDS ECH74115_3137 NC_011353.1 2912392 2912868 R identified by match to protein family HMM PF07278; bacteriophage terminase, small subunit complement(2912392..2912868) Escherichia coli O157:H7 str. EC4115 6966954 YP_002271431.1 CDS ECH74115_3140 NC_011353.1 2913324 2913791 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(2913324..2913791) Escherichia coli O157:H7 str. EC4115 6969270 YP_002271432.1 CDS ECH74115_3141 NC_011353.1 2913799 2913945 R hypothetical protein complement(2913799..2913945) Escherichia coli O157:H7 str. EC4115 6968849 YP_002271433.1 CDS ECH74115_3142 NC_011353.1 2913945 2914514 R anti-repressor protein Ant complement(2913945..2914514) Escherichia coli O157:H7 str. EC4115 6968031 YP_002271434.1 CDS ECH74115_3143 NC_011353.1 2914785 2915318 R identified by match to protein family HMM PF00959; lysozyme complement(2914785..2915318) Escherichia coli O157:H7 str. EC4115 6970454 YP_002271435.1 CDS ECH74115_3144 NC_011353.1 2915323 2915538 R identified by match to protein family HMM PF04971; hypothetical protein complement(2915323..2915538) Escherichia coli O157:H7 str. EC4115 6968486 YP_002271436.1 CDS ECH74115_3145 NC_011353.1 2915616 2915861 R identified by match to protein family HMM PF05696; hypothetical protein complement(2915616..2915861) Escherichia coli O157:H7 str. EC4115 6970383 YP_002271437.1 CDS ECH74115_3146 NC_011353.1 2915902 2916081 R identified by match to protein family HMM PF07125; hypothetical protein complement(2915902..2916081) Escherichia coli O157:H7 str. EC4115 6969390 YP_002271438.1 CDS ECH74115_3147 NC_011353.1 2916218 2918164 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(2916218..2918164) Escherichia coli O157:H7 str. EC4115 6971654 YP_002271439.1 CDS ECH74115_3148 NC_011353.1 2918405 2918551 D hypothetical protein 2918405..2918551 Escherichia coli O157:H7 str. EC4115 6967749 YP_002271440.1 CDS ECH74115_3150 NC_011353.1 2918593 2918712 D identified by glimmer; hypothetical protein 2918593..2918712 Escherichia coli O157:H7 str. EC4115 6966955 YP_002271441.1 CDS ECH74115_3151 NC_011353.1 2918759 2919817 R identified by match to protein family HMM PF01555; DNA methylase complement(2918759..2919817) Escherichia coli O157:H7 str. EC4115 6972395 YP_002271442.1 CDS ECH74115_3152 NC_011353.1 2919968 2920165 R hypothetical protein complement(2919968..2920165) Escherichia coli O157:H7 str. EC4115 6967067 YP_002271443.1 CDS ECH74115_3153 NC_011353.1 2920392 2921213 R identified by match to protein family HMM PF03589; antitermination protein Q complement(2920392..2921213) Escherichia coli O157:H7 str. EC4115 6969215 YP_002271444.1 CDS ECH74115_3154 NC_011353.1 2921210 2921584 R identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA complement(2921210..2921584) Escherichia coli O157:H7 str. EC4115 6968651 YP_002271445.1 CDS ECH74115_3155 NC_011353.1 2921597 2922646 R identified by match to protein family HMM PF06914; hypothetical protein complement(2921597..2922646) Escherichia coli O157:H7 str. EC4115 6969352 YP_002271446.1 CDS ECH74115_3157 NC_011353.1 2922996 2923253 R hypothetical protein complement(2922996..2923253) Escherichia coli O157:H7 str. EC4115 6970243 YP_002271447.1 CDS ECH74115_3158 NC_011353.1 2923875 2924024 R hypothetical protein complement(2923875..2924024) Escherichia coli O157:H7 str. EC4115 6969426 YP_002271448.1 CDS ECH74115_3159 NC_011353.1 2924095 2924457 R identified by match to protein family HMM PF04448; hypothetical protein complement(2924095..2924457) Escherichia coli O157:H7 str. EC4115 6971737 YP_002271449.1 CDS ECH74115_3160 NC_011353.1 2924454 2924825 R hypothetical protein complement(2924454..2924825) Escherichia coli O157:H7 str. EC4115 6971109 YP_002271450.1 CDS ECH74115_3161 NC_011353.1 2924861 2925073 R hypothetical protein complement(2924861..2925073) Escherichia coli O157:H7 str. EC4115 6967226 YP_002271451.1 CDS ECH74115_3162 NC_011353.1 2925122 2925478 R hypothetical protein complement(2925122..2925478) Escherichia coli O157:H7 str. EC4115 6969261 YP_002271452.1 CDS ECH74115_3163 NC_011353.1 2925535 2925930 R identified by match to protein family HMM PF06163; hypothetical protein complement(2925535..2925930) Escherichia coli O157:H7 str. EC4115 6970198 YP_002271453.1 CDS ECH74115_3164 NC_011353.1 2925946 2926716 R identified by match to protein family HMM PF07789; hypothetical protein complement(2925946..2926716) Escherichia coli O157:H7 str. EC4115 6969407 YP_002271454.1 CDS ECH74115_3165 NC_011353.1 2926751 2927173 R hypothetical protein complement(2926751..2927173) Escherichia coli O157:H7 str. EC4115 6970171 YP_002271455.1 CDS ECH74115_3166 NC_011353.1 2927205 2928245 R hypothetical protein complement(2927205..2928245) Escherichia coli O157:H7 str. EC4115 6969540 YP_002271456.1 CDS ECH74115_3167 NC_011353.1 2928217 2928708 R identified by match to protein family HMM PF06254; hypothetical protein complement(2928217..2928708) Escherichia coli O157:H7 str. EC4115 6971786 YP_002271457.1 CDS ECH74115_3168 NC_011353.1 2928752 2928979 R DNA-binding transcriptional regulator DicC complement(2928752..2928979) Escherichia coli O157:H7 str. EC4115 6971142 YP_002271458.1 CDS ECH74115_3169 NC_011353.1 2929085 2929291 R identified by glimmer; hypothetical protein complement(2929085..2929291) Escherichia coli O157:H7 str. EC4115 6967680 YP_002271459.1 CDS ECH74115_3170 NC_011353.1 2929330 2929464 D HTH-type transcriptional regulator DicA 2929330..2929464 Escherichia coli O157:H7 str. EC4115 6966909 YP_002271460.1 CDS ECH74115_3171 NC_011353.1 2929654 2929809 D identified by match to protein family HMM PF07151; hypothetical protein 2929654..2929809 Escherichia coli O157:H7 str. EC4115 6970134 YP_002271461.1 CDS ECH74115_3172 NC_011353.1 2929811 2929939 D identified by glimmer; hypothetical protein 2929811..2929939 Escherichia coli O157:H7 str. EC4115 6969498 YP_002271462.1 CDS ECH74115_3173 NC_011353.1 2929969 2930187 D identified by glimmer; hypothetical protein 2929969..2930187 Escherichia coli O157:H7 str. EC4115 6971832 YP_002271463.1 CDS ECH74115_3174 NC_011353.1 2930191 2930355 R hypothetical protein complement(2930191..2930355) Escherichia coli O157:H7 str. EC4115 6971151 YP_002271464.1 CDS ECH74115_3176 NC_011353.1 2930998 2931126 D identified by match to protein family HMM PF07358; hypothetical protein 2930998..2931126 Escherichia coli O157:H7 str. EC4115 6972133 YP_002271465.1 CDS ECH74115_3177 NC_011353.1 2931219 2933663 D identified by match to protein family HMM PF00929; match to protein family HMM PF06630; exonuclease family protein 2931219..2933663 Escherichia coli O157:H7 str. EC4115 6967414 YP_002271466.1 CDS ECH74115_3178 NC_011353.1 2933954 2935084 D identified by match to protein family HMM PF00589; match to protein family HMM PF09003; site-specific recombinase, phage integrase family 2933954..2935084 Escherichia coli O157:H7 str. EC4115 6966627 YP_002271467.1 CDS ECH74115_3179 NC_011353.1 2935130 2935246 R hypothetical protein complement(2935130..2935246) Escherichia coli O157:H7 str. EC4115 6969560 YP_002271468.1 CDS ECH74115_3181 NC_011353.1 2936108 2936698 R OspG complement(2936108..2936698) Escherichia coli O157:H7 str. EC4115 6968052 YP_002271469.1 CDS ECH74115_3182 NC_011353.1 2936874 2937377 R identified by match to protein family HMM PF03400; IS1, transposase orfB complement(2936874..2937377) Escherichia coli O157:H7 str. EC4115 6970665 YP_002271470.1 CDS ECH74115_3183 NC_011353.1 2937831 2938100 R prophage tail fiber C-terminus family protein complement(2937831..2938100) Escherichia coli O157:H7 str. EC4115 6970025 YP_002271471.1 CDS ECH74115_3184 NC_011353.1 2938102 2938380 R identified by match to protein family HMM PF06820; tail fiber protein complement(2938102..2938380) Escherichia coli O157:H7 str. EC4115 6971892 YP_002271472.1 CDS ECH74115_3186 NC_011353.1 2939351 2939479 D hypothetical protein 2939351..2939479 Escherichia coli O157:H7 str. EC4115 6967455 YP_002271473.1 CDS ECH74115_3187 NC_011353.1 2939480 2940079 R identified by match to protein family HMM PF06316; Ail/Lom family protein complement(2939480..2940079) Escherichia coli O157:H7 str. EC4115 6966844 YP_002271474.1 CDS ECH74115_3188 NC_011353.1 2940147 2943623 R identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein complement(2940147..2943623) Escherichia coli O157:H7 str. EC4115 6968703 YP_002271475.1 CDS ECH74115_3189 NC_011353.1 2943699 2943818 R identified by glimmer; hypothetical protein complement(2943699..2943818) Escherichia coli O157:H7 str. EC4115 6968732 YP_002271476.1 CDS ECH74115_3190 NC_011353.1 2943864 2944442 R identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I complement(2943864..2944442) Escherichia coli O157:H7 str. EC4115 6968133 YP_002271477.1 CDS ECH74115_3191 NC_011353.1 2944439 2945074 R identified by match to protein family HMM PF00877; tail assembly protein complement(2944439..2945074) Escherichia coli O157:H7 str. EC4115 6971903 YP_002271478.1 CDS ECH74115_3192 NC_011353.1 2945193 2945891 R identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L complement(2945193..2945891) Escherichia coli O157:H7 str. EC4115 6969723 YP_002271479.1 CDS ECH74115_3193 NC_011353.1 2945891 2946220 R identified by match to protein family HMM PF05939; phage minor tail protein complement(2945891..2946220) Escherichia coli O157:H7 str. EC4115 6970281 YP_002271480.1 CDS ECH74115_3194 NC_011353.1 2946217 2948862 R identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein complement(2946217..2948862) Escherichia coli O157:H7 str. EC4115 6968073 YP_002271481.1 CDS ECH74115_3195 NC_011353.1 2948906 2949190 R identified by match to protein family HMM TIGR01715; phage tail assembly protein T complement(2948906..2949190) Escherichia coli O157:H7 str. EC4115 6971102 YP_002271482.1 CDS ECH74115_3196 NC_011353.1 2949241 2949663 R identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G complement(2949241..2949663) Escherichia coli O157:H7 str. EC4115 6971755 YP_002271483.1 CDS ECH74115_3197 NC_011353.1 2949677 2950429 R identified by match to protein family HMM PF02368; major tail protein V complement(2949677..2950429) Escherichia coli O157:H7 str. EC4115 6969516 YP_002271484.1 CDS ECH74115_3198 NC_011353.1 2950437 2950835 R identified by match to protein family HMM PF06141; phage minor tail protein U complement(2950437..2950835) Escherichia coli O157:H7 str. EC4115 6970076 YP_002271485.1 CDS ECH74115_3199 NC_011353.1 2950848 2951471 R identified by match to protein family HMM PF06763; prophage minor tail protein Z complement(2950848..2951471) Escherichia coli O157:H7 str. EC4115 6968647 YP_002271486.1 CDS ECH74115_3200 NC_011353.1 2951474 2951722 R hypothetical protein complement(2951474..2951722) Escherichia coli O157:H7 str. EC4115 6969285 YP_002271487.1 CDS ECH74115_3201 NC_011353.1 2951748 2952074 R membrane protein complement(2951748..2952074) Escherichia coli O157:H7 str. EC4115 6967360 YP_002271488.1 CDS clpP NC_011353.1 2952162 2954117 R identified by match to protein family HMM PF00574; Clp protease domain-containing protein complement(2952162..2954117) Escherichia coli O157:H7 str. EC4115 6971002 YP_002271489.1 CDS ECH74115_3203 NC_011353.1 2954131 2955633 R identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family complement(2954131..2955633) Escherichia coli O157:H7 str. EC4115 6972182 YP_002271490.1 CDS ECH74115_3204 NC_011353.1 2955633 2955845 R hypothetical protein complement(2955633..2955845) Escherichia coli O157:H7 str. EC4115 6969385 YP_002271491.1 CDS ECH74115_3205 NC_011353.1 2955842 2957965 R identified by match to protein family HMM PF05876; phage terminase large subunit complement(2955842..2957965) Escherichia coli O157:H7 str. EC4115 6967100 YP_002271492.1 CDS ECH74115_3206 NC_011353.1 2957962 2958438 R identified by match to protein family HMM PF07278; bacteriophage terminase, small subunit complement(2957962..2958438) Escherichia coli O157:H7 str. EC4115 6971567 YP_002271493.1 CDS ECH74115_3207 NC_011353.1 2958851 2959318 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(2958851..2959318) Escherichia coli O157:H7 str. EC4115 6971484 YP_002271494.1 CDS ECH74115_3208 NC_011353.1 2959617 2960150 R identified by match to protein family HMM PF00959; lysozyme complement(2959617..2960150) Escherichia coli O157:H7 str. EC4115 6970678 YP_002271495.1 CDS ECH74115_3209 NC_011353.1 2960187 2960744 R hypothetical protein complement(2960187..2960744) Escherichia coli O157:H7 str. EC4115 6970562 YP_002271496.1 CDS ECH74115_3210 NC_011353.1 2960748 2960963 R identified by match to protein family HMM PF04971; hypothetical protein complement(2960748..2960963) Escherichia coli O157:H7 str. EC4115 6969783 YP_002271497.1 CDS ECH74115_3211 NC_011353.1 2961041 2961286 R identified by match to protein family HMM PF05696; hypothetical protein complement(2961041..2961286) Escherichia coli O157:H7 str. EC4115 6966638 YP_002271498.1 CDS ECH74115_3212 NC_011353.1 2961327 2961506 R identified by match to protein family HMM PF07125; hypothetical protein complement(2961327..2961506) Escherichia coli O157:H7 str. EC4115 6967268 YP_002271499.1 CDS ECH74115_3213 NC_011353.1 2961519 2961644 R hypothetical protein complement(2961519..2961644) Escherichia coli O157:H7 str. EC4115 6968290 YP_002271500.1 CDS ECH74115_3214 NC_011353.1 2961641 2963587 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(2961641..2963587) Escherichia coli O157:H7 str. EC4115 6971663 YP_002271501.1 CDS ECH74115_3220 NC_011353.1 2964795 2965229 R identified by match to protein family HMM PF06530; antitermination protein Q complement(2964795..2965229) Escherichia coli O157:H7 str. EC4115 6971045 YP_002271502.1 CDS ECH74115_3221 NC_011353.1 2965315 2965452 R hypothetical protein complement(2965315..2965452) Escherichia coli O157:H7 str. EC4115 6971740 YP_002271503.1 CDS rusA NC_011353.1 2965452 2965814 R DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS complement(2965452..2965814) Escherichia coli O157:H7 str. EC4115 6966966 YP_002271504.1 CDS ECH74115_3223 NC_011353.1 2965811 2966101 R identified by match to protein family HMM PF07102; hypothetical protein complement(2965811..2966101) Escherichia coli O157:H7 str. EC4115 6967910 YP_002271505.1 CDS ECH74115_3224 NC_011353.1 2966264 2966719 R DLP12 prophage; hypothetical protein complement(2966264..2966719) Escherichia coli O157:H7 str. EC4115 6969016 YP_002271506.1 CDS ECH74115_3225 NC_011353.1 2966934 2967731 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(2966934..2967731) Escherichia coli O157:H7 str. EC4115 6969471 YP_002271507.1 CDS ECH74115_3226 NC_011353.1 2967908 2968030 D hypothetical protein 2967908..2968030 Escherichia coli O157:H7 str. EC4115 6969874 YP_002271508.1 CDS ECH74115_3227 NC_011353.1 2968757 2970283 R identified by match to protein family HMM PF00239; match to protein family HMM PF07508; recombinase family protein complement(2968757..2970283) Escherichia coli O157:H7 str. EC4115 6971042 YP_002271509.1 CDS emrE NC_011353.1 2970540 2970872 R member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein complement(2970540..2970872) Escherichia coli O157:H7 str. EC4115 6971497 YP_002271510.1 CDS ECH74115_3229 NC_011353.1 2970940 2971242 R hypothetical protein complement(2970940..2971242) Escherichia coli O157:H7 str. EC4115 6971971 YP_002271511.1 CDS ECH74115_3230 NC_011353.1 2971239 2971676 R identified by match to protein family HMM PF06992; replication protein P complement(2971239..2971676) Escherichia coli O157:H7 str. EC4115 6968051 YP_002271512.1 CDS ECH74115_3231 NC_011353.1 2971731 2972057 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2971731..2972057 Escherichia coli O157:H7 str. EC4115 6969217 YP_002271513.1 CDS ECH74115_3232 NC_011353.1 2972054 2972944 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2972054..2972944 Escherichia coli O157:H7 str. EC4115 6969679 YP_002271514.1 CDS ECH74115_3234 NC_011353.1 2973250 2974254 R identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; phage replication protein O complement(2973250..2974254) Escherichia coli O157:H7 str. EC4115 6971037 YP_002271515.1 CDS ECH74115_3235 NC_011353.1 2974266 2974805 R identified by match to protein family HMM PF06254; hypothetical protein complement(2974266..2974805) Escherichia coli O157:H7 str. EC4115 6971852 YP_002271516.1 CDS ECH74115_3236 NC_011353.1 2974875 2975105 R hypothetical protein complement(2974875..2975105) Escherichia coli O157:H7 str. EC4115 6967191 YP_002271517.1 CDS ECH74115_3237 NC_011353.1 2975285 2975899 D identified by match to protein family HMM PF00717; repressor protein 2975285..2975899 Escherichia coli O157:H7 str. EC4115 6967633 YP_002271518.1 CDS ECH74115_3238 NC_011353.1 2975980 2977041 D hypothetical protein 2975980..2977041 Escherichia coli O157:H7 str. EC4115 6966606 YP_002271519.1 CDS kiL NC_011353.1 2977877 2978083 D protein KiL 2977877..2978083 Escherichia coli O157:H7 str. EC4115 6968554 YP_002271520.1 CDS gam NC_011353.1 2978159 2978455 D identified by match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 2978159..2978455 Escherichia coli O157:H7 str. EC4115 6968283 YP_002271521.1 CDS bet NC_011353.1 2978461 2979246 D identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 2978461..2979246 Escherichia coli O157:H7 str. EC4115 6968747 YP_002271522.1 CDS exo NC_011353.1 2979243 2979920 D identified by match to protein family HMM PF09588; exonuclease 2979243..2979920 Escherichia coli O157:H7 str. EC4115 6970584 YP_002271523.1 CDS ECH74115_3243 NC_011353.1 2980153 2980266 D hypothetical protein 2980153..2980266 Escherichia coli O157:H7 str. EC4115 6971022 YP_002271524.1 CDS ECH74115_3244 NC_011353.1 2980343 2980558 D hypothetical protein 2980343..2980558 Escherichia coli O157:H7 str. EC4115 6968853 YP_002271525.1 CDS ECH74115_3245 NC_011353.1 2980875 2981822 D identified by match to protein family HMM PF04447; hypothetical protein 2980875..2981822 Escherichia coli O157:H7 str. EC4115 6969129 YP_002271526.1 CDS ECH74115_3249 NC_011353.1 2983236 2983379 D hypothetical protein 2983236..2983379 Escherichia coli O157:H7 str. EC4115 6970898 YP_002271527.1 CDS ECH74115_3250 NC_011353.1 2983650 2983790 D identified by match to protein family HMM PF06806; excisionase 2983650..2983790 Escherichia coli O157:H7 str. EC4115 6971164 YP_002271528.1 CDS ECH74115_3251 NC_011353.1 2983824 2985110 D identified by match to protein family HMM PF00589; Int protein 2983824..2985110 Escherichia coli O157:H7 str. EC4115 6967490 YP_002271529.1 CDS ECH74115_3252 NC_011353.1 2985185 2985832 D hypothetical protein 2985185..2985832 Escherichia coli O157:H7 str. EC4115 6966795 YP_002271530.1 CDS ECH74115_3253 NC_011353.1 2985980 2986711 R identified by match to protein family HMM PF00528; ABC transporter quaternary amine uptake (QAT) family, permease complement(2985980..2986711) Escherichia coli O157:H7 str. EC4115 6967063 YP_002271531.1 CDS ECH74115_3254 NC_011353.1 2986716 2987642 R identified by match to protein family HMM PF00005; ABC transporter quaternary amine uptake (QAT) family, ATP-binding protein complement(2986716..2987642) Escherichia coli O157:H7 str. EC4115 6967225 YP_002271532.1 CDS ECH74115_3255 NC_011353.1 2987635 2988792 R identified by match to protein family HMM PF00528; ABC transporter quaternary amine uptake (QAT) family, permease complement(2987635..2988792) Escherichia coli O157:H7 str. EC4115 6969045 YP_002271533.1 CDS ECH74115_3256 NC_011353.1 2988799 2989716 R identified by match to protein family HMM PF04069; ABC transporter quaternary amine uptake transporter (QAT) family, substrate-binding protein complement(2988799..2989716) Escherichia coli O157:H7 str. EC4115 6968401 YP_002271534.1 CDS bglX NC_011353.1 2989968 2992265 R identified by match to protein family HMM PF00933; match to protein family HMM PF01915; beta-glucosidase, periplasmic complement(2989968..2992265) Escherichia coli O157:H7 str. EC4115 6970310 YP_002271535.1 CDS ECH74115_3258 NC_011353.1 2992266 2992424 D identified by glimmer; hypothetical protein 2992266..2992424 Escherichia coli O157:H7 str. EC4115 6970318 YP_002271536.1 CDS dld NC_011353.1 2992461 2994176 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2992461..2994176 Escherichia coli O157:H7 str. EC4115 6969656 YP_002271537.1 CDS pbpG NC_011353.1 2994214 2995155 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2994214..2995155) Escherichia coli O157:H7 str. EC4115 6971524 YP_002271538.1 CDS ECH74115_3261 NC_011353.1 2995320 2995931 R identified by match to protein family HMM PF06930; hypothetical protein complement(2995320..2995931) Escherichia coli O157:H7 str. EC4115 6967765 YP_002271539.1 CDS ECH74115_3263 NC_011353.1 2996077 2996655 D identified by match to protein family HMM PF09335; hypothetical protein 2996077..2996655 Escherichia coli O157:H7 str. EC4115 6967922 YP_002271540.1 CDS ECH74115_3262 NC_011353.1 2996646 2996759 R hypothetical protein complement(2996646..2996759) Escherichia coli O157:H7 str. EC4115 6967784 YP_002271541.1 CDS ECH74115_3264 NC_011353.1 2996785 2997546 R identified by match to protein family HMM PF00106; acetoin dehydrogenase complement(2996785..2997546) Escherichia coli O157:H7 str. EC4115 6966975 YP_002271542.1 CDS ECH74115_3265 NC_011353.1 2997599 2999035 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2997599..2999035) Escherichia coli O157:H7 str. EC4115 6966965 YP_002271543.1 CDS ECH74115_3266 NC_011353.1 2999730 3000680 R identified by match to protein family HMM PF01207; tRNA-dihydrouridine synthase C complement(2999730..3000680) Escherichia coli O157:H7 str. EC4115 6969399 YP_002271544.1 CDS ECH74115_3267 NC_011353.1 3000839 3002032 R catalyzes the formation of catechol from salicylate; salicylate hydroxylase complement(3000839..3002032) Escherichia coli O157:H7 str. EC4115 6972154 YP_002271545.1 CDS maiA NC_011353.1 3002047 3002691 R identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262; maleylacetoacetate isomerase complement(3002047..3002691) Escherichia coli O157:H7 str. EC4115 6968260 YP_002271546.1 CDS ECH74115_3269 NC_011353.1 3002700 3003401 R identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase family protein complement(3002700..3003401) Escherichia coli O157:H7 str. EC4115 6970336 YP_002271547.1 CDS gtdA NC_011353.1 3003416 3004444 R identified by match to protein family HMM PF07883; match to protein family HMM TIGR02272; gentisate 1,2-dioxygenase complement(3003416..3004444) Escherichia coli O157:H7 str. EC4115 6971767 YP_002271548.1 CDS ECH74115_3271 NC_011353.1 3004456 3005814 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter complement(3004456..3005814) Escherichia coli O157:H7 str. EC4115 6970966 YP_002271549.1 CDS ECH74115_3272 NC_011353.1 3005941 3006849 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3005941..3006849 Escherichia coli O157:H7 str. EC4115 6969784 YP_002271550.1 CDS ECH74115_3273 NC_011353.1 3006980 3007378 D identified by match to protein family HMM PF03788; hypothetical protein 3006980..3007378 Escherichia coli O157:H7 str. EC4115 6969674 YP_002271551.1 CDS ECH74115_3274 NC_011353.1 3007375 3008070 D identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659; hypothetical protein 3007375..3008070 Escherichia coli O157:H7 str. EC4115 6970346 YP_002271552.1 CDS cdd NC_011353.1 3008200 3009084 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 3008200..3009084 Escherichia coli O157:H7 str. EC4115 6970558 YP_002271553.1 CDS sanA NC_011353.1 3009234 3009953 D identified by match to protein family HMM PF02698; hypothetical protein 3009234..3009953 Escherichia coli O157:H7 str. EC4115 6968706 YP_002271554.1 CDS ECH74115_3277 NC_011353.1 3009956 3010195 D hypothetical protein 3009956..3010195 Escherichia coli O157:H7 str. EC4115 6966778 YP_002271555.1 CDS ECH74115_3278 NC_011353.1 3010389 3011627 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 3010389..3011627 Escherichia coli O157:H7 str. EC4115 6971638 YP_002271556.1 CDS ECH74115_3279 NC_011353.1 3011621 3012856 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 3011621..3012856 Escherichia coli O157:H7 str. EC4115 6969599 YP_002271557.1 CDS ECH74115_3280 NC_011353.1 3012902 3013021 D hypothetical protein 3012902..3013021 Escherichia coli O157:H7 str. EC4115 6967236 YP_002271558.1 CDS mglC NC_011353.1 3013099 3014109 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(3013099..3014109) Escherichia coli O157:H7 str. EC4115 6970868 YP_002271559.1 CDS mglA NC_011353.1 3014125 3015645 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(3014125..3015645) Escherichia coli O157:H7 str. EC4115 6968451 YP_002271560.1 CDS mglB NC_011353.1 3015706 3016704 R identified by match to protein family HMM PF00532; galactose ABC transporter periplasmic galactose-binding protein complement(3015706..3016704) Escherichia coli O157:H7 str. EC4115 6968903 YP_002271561.1 CDS ECH74115_3284 NC_011353.1 3016776 3016934 D identified by glimmer; hypothetical protein 3016776..3016934 Escherichia coli O157:H7 str. EC4115 6972090 YP_002271562.1 CDS galS NC_011353.1 3016983 3018023 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(3016983..3018023) Escherichia coli O157:H7 str. EC4115 6970931 YP_002271563.1 CDS ECH74115_3286 NC_011353.1 3018165 3019322 R identified by match to protein family HMM PF04171; match to protein family HMM PF04235; hypothetical protein complement(3018165..3019322) Escherichia coli O157:H7 str. EC4115 6967278 YP_002271564.1 CDS folE NC_011353.1 3019339 3020007 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(3019339..3020007) Escherichia coli O157:H7 str. EC4115 6966870 YP_002271565.1 CDS fghA1 NC_011353.1 3020265 3021101 D identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase 3020265..3021101 Escherichia coli O157:H7 str. EC4115 6970595 YP_002271566.1 CDS cirA NC_011353.1 3021133 3023112 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(3021133..3023112) Escherichia coli O157:H7 str. EC4115 6971375 YP_002271567.1 CDS ECH74115_3291 NC_011353.1 3023253 3023387 D identified by glimmer; hypothetical protein 3023253..3023387 Escherichia coli O157:H7 str. EC4115 6967371 YP_002271568.1 CDS lysP NC_011353.1 3023404 3024873 R identified by match to protein family HMM PF00324; lysine transporter complement(3023404..3024873) Escherichia coli O157:H7 str. EC4115 6966618 YP_002271569.1 CDS ECH74115_3293 NC_011353.1 3025078 3025959 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(3025078..3025959) Escherichia coli O157:H7 str. EC4115 6969003 YP_002271570.1 CDS ECH74115_3294 NC_011353.1 3026058 3027107 D identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698; hypothetical protein 3026058..3027107 Escherichia coli O157:H7 str. EC4115 6970219 YP_002271571.1 CDS nfo NC_011353.1 3027181 3028038 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 3027181..3028038 Escherichia coli O157:H7 str. EC4115 6969391 YP_002271572.1 CDS ECH74115_3296 NC_011353.1 3028041 3029129 D identified by match to protein family HMM PF00294; hypothetical protein 3028041..3029129 Escherichia coli O157:H7 str. EC4115 6971839 YP_002271573.1 CDS ECH74115_3297 NC_011353.1 3029185 3030435 R identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC family complement(3029185..3030435) Escherichia coli O157:H7 str. EC4115 6972024 YP_002271574.1 CDS rihB NC_011353.1 3030535 3031476 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(3030535..3031476) Escherichia coli O157:H7 str. EC4115 6967821 YP_002271575.1 CDS nsr NC_011353.1 3031606 3032304 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 3031606..3032304 Escherichia coli O157:H7 str. EC4115 6967210 YP_002271576.1 CDS ECH74115_3300 NC_011353.1 3032375 3033625 R identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC family complement(3032375..3033625) Escherichia coli O157:H7 str. EC4115 6969084 YP_002271577.1 CDS ECH74115_3301 NC_011353.1 3033719 3034657 R identified by match to protein family HMM PF04227; indigoidine synthase A like protein complement(3033719..3034657) Escherichia coli O157:H7 str. EC4115 6968448 YP_002271578.1 CDS ECH74115_3302 NC_011353.1 3034645 3035586 R identified by match to protein family HMM PF00294; hypothetical protein complement(3034645..3035586) Escherichia coli O157:H7 str. EC4115 6970355 YP_002271579.1 CDS fruA NC_011353.1 3036010 3037701 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(3036010..3037701) Escherichia coli O157:H7 str. EC4115 6969714 YP_002271580.1 CDS fruK NC_011353.1 3037718 3038656 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(3037718..3038656) Escherichia coli O157:H7 str. EC4115 6970326 YP_002271581.1 CDS fruB NC_011353.1 3038656 3039786 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; PTS system fructose-specific transporter subunit IIA/HPr protein complement(3038656..3039786) Escherichia coli O157:H7 str. EC4115 6966875 YP_002271582.1 CDS ECH74115_3306 NC_011353.1 3039952 3040083 D hypothetical protein 3039952..3040083 Escherichia coli O157:H7 str. EC4115 6971905 YP_002271583.1 CDS setB NC_011353.1 3040154 3041335 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899; sugar efflux transporter B 3040154..3041335 Escherichia coli O157:H7 str. EC4115 6968389 YP_002271584.1 CDS ECH74115_3307 NC_011353.1 3041332 3041718 R hypothetical protein complement(3041332..3041718) Escherichia coli O157:H7 str. EC4115 6970071 YP_002271585.1 CDS ECH74115_3309 NC_011353.1 3041741 3042313 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 3041741..3042313 Escherichia coli O157:H7 str. EC4115 6967782 YP_002271586.1 CDS ECH74115_3310 NC_011353.1 3042536 3044002 D identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase family protein 3042536..3044002 Escherichia coli O157:H7 str. EC4115 6971277 YP_002271587.1 CDS ECH74115_3311 NC_011353.1 3044120 3045106 D identified by match to protein family HMM PF02492; match to protein family HMM PF07683; CobW/P47K family protein 3044120..3045106 Escherichia coli O157:H7 str. EC4115 6967608 YP_002271588.1 CDS ECH74115_3312 NC_011353.1 3045145 3045858 D identified by match to protein family HMM PF01569; PAP2 family protein 3045145..3045858 Escherichia coli O157:H7 str. EC4115 6966851 YP_002271589.1 CDS spr NC_011353.1 3046271 3046837 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 3046271..3046837 Escherichia coli O157:H7 str. EC4115 6970347 YP_002271590.1 CDS ECH74115_3314 NC_011353.1 3047081 3048574 D identified by match to protein family HMM PF00563; hypothetical protein 3047081..3048574 Escherichia coli O157:H7 str. EC4115 6969490 YP_002271591.1 CDS ECH74115_3315 NC_011353.1 3048656 3050470 D identified by match to protein family HMM PF00496; ABC transporter periplasmic solute-binding protein 3048656..3050470 Escherichia coli O157:H7 str. EC4115 6968255 YP_002271592.1 CDS ECH74115_3316 NC_011353.1 3050471 3051565 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 3050471..3051565 Escherichia coli O157:H7 str. EC4115 6970293 YP_002271593.1 CDS ECH74115_3317 NC_011353.1 3051565 3052590 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 3051565..3052590 Escherichia coli O157:H7 str. EC4115 6967116 YP_002271594.1 CDS ECH74115_3318 NC_011353.1 3052592 3054181 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3052592..3054181 Escherichia coli O157:H7 str. EC4115 6969196 YP_002271595.1 CDS ECH74115_3319 NC_011353.1 3054185 3054529 R hypothetical protein complement(3054185..3054529) Escherichia coli O157:H7 str. EC4115 6967858 YP_002271596.1 CDS bcr NC_011353.1 3054862 3056052 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(3054862..3056052) Escherichia coli O157:H7 str. EC4115 6967131 YP_002271597.1 CDS rsuA NC_011353.1 3056080 3056775 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(3056080..3056775) Escherichia coli O157:H7 str. EC4115 6969545 YP_002271598.1 CDS ECH74115_3322 NC_011353.1 3056924 3058684 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; helicase 3056924..3058684 Escherichia coli O157:H7 str. EC4115 6971764 YP_002271599.1 CDS ECH74115_3323 NC_011353.1 3058809 3059093 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3058809..3059093 Escherichia coli O157:H7 str. EC4115 6969347 YP_002271600.1 CDS ndpA NC_011353.1 3059232 3060239 R identified by match to protein family HMM PF04245; nucleoid-associated protein NdpA complement(3059232..3060239) Escherichia coli O157:H7 str. EC4115 6969828 YP_002271601.1 CDS ECH74115_3325 NC_011353.1 3060284 3060400 R identified by glimmer; hypothetical protein complement(3060284..3060400) Escherichia coli O157:H7 str. EC4115 6967642 YP_002271602.1 CDS ECH74115_3326 NC_011353.1 3060421 3060648 D identified by match to protein family HMM PF07208; hypothetical protein 3060421..3060648 Escherichia coli O157:H7 str. EC4115 6968238 YP_002271603.1 CDS ECH74115_3327 NC_011353.1 3060668 3062428 D identified by match to protein family HMM PF00884; sulfatase family protein 3060668..3062428 Escherichia coli O157:H7 str. EC4115 6971847 YP_002271604.1 CDS ECH74115_3329 NC_011353.1 3062680 3065271 R identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; autotransporter IS5K-containing complement(3062680..3065271) Escherichia coli O157:H7 str. EC4115 6972434 YP_002271605.1 CDS narP NC_011353.1 3065591 3066238 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 3065591..3066238 Escherichia coli O157:H7 str. EC4115 6970196 YP_002271606.1 CDS ECH74115_3331 NC_011353.1 3066273 3067325 R identified by match to protein family HMM PF03918; cytochrome c-type biogenesis family protein complement(3066273..3067325) Escherichia coli O157:H7 str. EC4115 6969192 YP_002271607.1 CDS dsbE NC_011353.1 3067322 3067879 R identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385; thiol:disulfide interchange protein DsbE complement(3067322..3067879) Escherichia coli O157:H7 str. EC4115 6967171 YP_002271608.1 CDS ccmF NC_011353.1 3067876 3069819 R identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF complement(3067876..3069819) Escherichia coli O157:H7 str. EC4115 6967800 YP_002271609.1 CDS ccmE NC_011353.1 3069816 3070295 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(3069816..3070295) Escherichia coli O157:H7 str. EC4115 6970386 YP_002271610.1 CDS ccmD NC_011353.1 3070292 3070501 R identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141; heme exporter protein D complement(3070292..3070501) Escherichia coli O157:H7 str. EC4115 6969633 YP_002271611.1 CDS ccmC NC_011353.1 3070498 3071235 R identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein C complement(3070498..3071235) Escherichia coli O157:H7 str. EC4115 6966912 YP_002271612.1 CDS ccmB NC_011353.1 3071277 3071939 R identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB complement(3071277..3071939) Escherichia coli O157:H7 str. EC4115 6969376 YP_002271613.1 CDS ccmA NC_011353.1 3071936 3072553 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(3071936..3072553) Escherichia coli O157:H7 str. EC4115 6971418 YP_002271614.1 CDS napC NC_011353.1 3072572 3073174 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(3072572..3073174) Escherichia coli O157:H7 str. EC4115 6967394 YP_002271615.1 CDS napB NC_011353.1 3073184 3073633 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(3073184..3073633) Escherichia coli O157:H7 str. EC4115 6969512 YP_002271616.1 CDS napH NC_011353.1 3073630 3074493 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(3073630..3074493) Escherichia coli O157:H7 str. EC4115 6971738 YP_002271617.1 CDS napG NC_011353.1 3074480 3075175 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(3074480..3075175) Escherichia coli O157:H7 str. EC4115 6968211 YP_002271618.1 CDS napA NC_011353.1 3075182 3077668 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(3075182..3077668) Escherichia coli O157:H7 str. EC4115 6968316 YP_002271619.1 CDS napD NC_011353.1 3077665 3077928 R identified by match to protein family HMM PF03927; assembly protein for periplasmic nitrate reductase complement(3077665..3077928) Escherichia coli O157:H7 str. EC4115 6970945 YP_002271620.1 CDS napF NC_011353.1 3077918 3078412 R Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein complement(3077918..3078412) Escherichia coli O157:H7 str. EC4115 6971560 YP_002271621.1 CDS ECH74115_3346 NC_011353.1 3078521 3078685 D identified by glimmer; hypothetical protein 3078521..3078685 Escherichia coli O157:H7 str. EC4115 6967112 YP_002271622.1 CDS eco NC_011353.1 3078819 3079307 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 3078819..3079307 Escherichia coli O157:H7 str. EC4115 6966710 YP_002271623.1 CDS mqo NC_011353.1 3079457 3081103 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(3079457..3081103) Escherichia coli O157:H7 str. EC4115 6968390 YP_002271624.1 CDS ECH74115_3349 NC_011353.1 3081321 3082964 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component complement(3081321..3082964) Escherichia coli O157:H7 str. EC4115 6969050 YP_002271625.1 CDS alkB NC_011353.1 3083040 3083690 R identified by match to protein family HMM PF03171; match to protein family HMM TIGR00568; alkylated DNA repair protein AlkB complement(3083040..3083690) Escherichia coli O157:H7 str. EC4115 6970378 YP_002271626.1 CDS ada NC_011353.1 3083690 3084754 R identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589; regulatory protein Ada complement(3083690..3084754) Escherichia coli O157:H7 str. EC4115 6969466 YP_002271627.1 CDS apbE NC_011353.1 3084828 3085883 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(3084828..3085883) Escherichia coli O157:H7 str. EC4115 6969875 YP_002271628.1 CDS ompC NC_011353.1 3085995 3087098 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(3085995..3087098) Escherichia coli O157:H7 str. EC4115 6970891 YP_002271629.1 CDS ECH74115_3354 NC_011353.1 3087490 3087615 R hypothetical protein complement(3087490..3087615) Escherichia coli O157:H7 str. EC4115 6972251 YP_002271630.1 CDS yojN NC_011353.1 3087837 3090509 D identified by match to protein family HMM PF01627; match to protein family HMM PF02518; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 3087837..3090509 Escherichia coli O157:H7 str. EC4115 6970967 YP_002271631.1 CDS rcsB NC_011353.1 3090526 3091176 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 3090526..3091176 Escherichia coli O157:H7 str. EC4115 6971627 YP_002271632.1 CDS rcsC NC_011353.1 3091376 3094225 R identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF09456; hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(3091376..3094225) Escherichia coli O157:H7 str. EC4115 6970850 YP_002271633.1 CDS ECH74115_3359 NC_011353.1 3094500 3095276 R hypothetical protein complement(3094500..3095276) Escherichia coli O157:H7 str. EC4115 6967175 YP_002271634.1 CDS ECH74115_3362 NC_011353.1 3096931 3101367 R identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin family protein complement(3096931..3101367) Escherichia coli O157:H7 str. EC4115 6970636 YP_002271635.1 CDS ECH74115_3363 NC_011353.1 3101469 3102092 R identified by match to protein family HMM PF06672; hypothetical protein complement(3101469..3102092) Escherichia coli O157:H7 str. EC4115 6969485 YP_002271636.1 CDS ECH74115_3364 NC_011353.1 3102089 3103687 R hypothetical protein complement(3102089..3103687) Escherichia coli O157:H7 str. EC4115 6971723 YP_002271637.1 CDS gyrA NC_011353.1 3103925 3106552 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(3103925..3106552) Escherichia coli O157:H7 str. EC4115 6967442 YP_002271638.1 CDS ubiG NC_011353.1 3106699 3107421 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 3106699..3107421 Escherichia coli O157:H7 str. EC4115 6966820 YP_002271639.1 CDS ECH74115_3367 NC_011353.1 3107562 3111266 R identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601; adhesin complement(3107562..3111266) Escherichia coli O157:H7 str. EC4115 6967999 YP_002271640.1 CDS nrdA NC_011353.1 3112010 3114295 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3112010..3114295 Escherichia coli O157:H7 str. EC4115 6967570 YP_002271641.1 CDS nrdB NC_011353.1 3114483 3115652 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 3114483..3115652 Escherichia coli O157:H7 str. EC4115 6969643 YP_002271642.1 CDS ECH74115_3370 NC_011353.1 3115652 3115906 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 3115652..3115906 Escherichia coli O157:H7 str. EC4115 6969164 YP_002271643.1 CDS ECH74115_3371 NC_011353.1 3115960 3116610 R identified by match to protein family HMM PF06293; hypothetical protein complement(3115960..3116610) Escherichia coli O157:H7 str. EC4115 6970617 YP_002271644.1 CDS ECH74115_3372 NC_011353.1 3116691 3117881 R identified by match to protein family HMM PF07690; major facilitator family transporter complement(3116691..3117881) Escherichia coli O157:H7 str. EC4115 6969819 YP_002271645.1 CDS ECH74115_3373 NC_011353.1 3118033 3118911 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; hypothetical protein 3118033..3118911 Escherichia coli O157:H7 str. EC4115 6972215 YP_002271646.1 CDS ECH74115_3374 NC_011353.1 3119065 3119196 D identified by glimmer; hypothetical protein 3119065..3119196 Escherichia coli O157:H7 str. EC4115 6971383 YP_002271647.1 CDS ECH74115_3375 NC_011353.1 3119375 3120445 D hypothetical protein 3119375..3120445 Escherichia coli O157:H7 str. EC4115 6970986 YP_002271648.1 CDS glpQ NC_011353.1 3120669 3121745 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(3120669..3121745) Escherichia coli O157:H7 str. EC4115 6970744 YP_002271649.1 CDS glpT NC_011353.1 3121750 3123108 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(3121750..3123108) Escherichia coli O157:H7 str. EC4115 6967820 YP_002271650.1 CDS glpA NC_011353.1 3123381 3125009 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 3123381..3125009 Escherichia coli O157:H7 str. EC4115 6967200 YP_002271651.1 CDS glpB NC_011353.1 3124999 3126258 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 3124999..3126258 Escherichia coli O157:H7 str. EC4115 6969063 YP_002271652.1 CDS glpC NC_011353.1 3126255 3127445 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 3126255..3127445 Escherichia coli O157:H7 str. EC4115 6968398 YP_002271653.1 CDS ECH74115_3381 NC_011353.1 3127470 3127595 D identified by glimmer; hypothetical protein 3127470..3127595 Escherichia coli O157:H7 str. EC4115 6968782 YP_002271654.1 CDS ECH74115_3382 NC_011353.1 3127638 3128564 D identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 3127638..3128564 Escherichia coli O157:H7 str. EC4115 6967971 YP_002271655.1 CDS ECH74115_3384 NC_011353.1 3129425 3130183 R major facilitator superfamily protein complement(3129425..3130183) Escherichia coli O157:H7 str. EC4115 6969996 YP_002271656.1 CDS ECH74115_3385 NC_011353.1 3130254 3130580 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 3130254..3130580 Escherichia coli O157:H7 str. EC4115 6966620 YP_002271657.1 CDS ECH74115_3386 NC_011353.1 3130577 3131467 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 3130577..3131467 Escherichia coli O157:H7 str. EC4115 6971633 YP_002271658.1 CDS ECH74115_3387 NC_011353.1 3131470 3132027 R major facilitator family transporter complement(3131470..3132027) Escherichia coli O157:H7 str. EC4115 6971336 YP_002271659.1 CDS ECH74115_3388 NC_011353.1 3132084 3133289 R identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing protein complement(3132084..3133289) Escherichia coli O157:H7 str. EC4115 6970405 YP_002271660.1 CDS ECH74115_3389 NC_011353.1 3133304 3134086 R identified by match to protein family HMM PF01614; match to protein family HMM PF09339; IclR family transcriptional regulator complement(3133304..3134086) Escherichia coli O157:H7 str. EC4115 6970073 YP_002271661.1 CDS ECH74115_3390 NC_011353.1 3134306 3135508 R identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200; competence damage-inducible protein A complement(3134306..3135508) Escherichia coli O157:H7 str. EC4115 6969115 YP_002271662.1 CDS yfaZ NC_011353.1 3135608 3136150 R identified by match to protein family HMM PF07437; YfaZ protein complement(3135608..3136150) Escherichia coli O157:H7 str. EC4115 6966600 YP_002271663.1 CDS ECH74115_3392 NC_011353.1 3136492 3136854 D identified by match to protein family HMM PF00293; NUDIX family hydrolase 3136492..3136854 Escherichia coli O157:H7 str. EC4115 6968946 YP_002271664.1 CDS ECH74115_3393 NC_011353.1 3136893 3137495 R identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein complement(3136893..3137495) Escherichia coli O157:H7 str. EC4115 6968616 YP_002271665.1 CDS arnB NC_011353.1 3137785 3138942 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 3137785..3138942 Escherichia coli O157:H7 str. EC4115 6970708 YP_002271666.1 CDS arnC NC_011353.1 3138946 3139914 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 3138946..3139914 Escherichia coli O157:H7 str. EC4115 6969009 YP_002271667.1 CDS arnA NC_011353.1 3139914 3141896 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 3139914..3141896 Escherichia coli O157:H7 str. EC4115 6969474 YP_002271668.1 CDS ECH74115_3397 NC_011353.1 3141893 3142783 D identified by match to protein family HMM PF01522; polysaccharide deacetylase domain-containing protein 3141893..3142783 Escherichia coli O157:H7 str. EC4115 6970105 YP_002271669.1 CDS arnT NC_011353.1 3142783 3144435 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 3142783..3144435 Escherichia coli O157:H7 str. EC4115 6970723 YP_002271670.1 CDS ECH74115_3399 NC_011353.1 3144432 3144767 D identified by match to protein family HMM PF00893; SMR family multidrug resistance protein 3144432..3144767 Escherichia coli O157:H7 str. EC4115 6971349 YP_002271671.1 CDS ECH74115_3401 NC_011353.1 3144767 3145153 D hypothetical protein 3144767..3145153 Escherichia coli O157:H7 str. EC4115 6971904 YP_002271672.1 CDS pmrD NC_011353.1 3145147 3145413 R polymyxin B resistance protein pmrD complement(3145147..3145413) Escherichia coli O157:H7 str. EC4115 6968481 YP_002271673.1 CDS menE NC_011353.1 3145523 3146878 R identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923; O-succinylbenzoic acid--CoA ligase complement(3145523..3146878) Escherichia coli O157:H7 str. EC4115 6966794 YP_002271674.1 CDS menC NC_011353.1 3146875 3147837 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(3146875..3147837) Escherichia coli O157:H7 str. EC4115 6968030 YP_002271675.1 CDS menB NC_011353.1 3147837 3148694 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(3147837..3148694) Escherichia coli O157:H7 str. EC4115 6969008 YP_002271676.1 CDS ECH74115_3405 NC_011353.1 3148709 3149467 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(3148709..3149467) Escherichia coli O157:H7 str. EC4115 6971029 YP_002271677.1 CDS menD NC_011353.1 3149464 3151134 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(3149464..3151134) Escherichia coli O157:H7 str. EC4115 6971835 YP_002271678.1 CDS menF NC_011353.1 3151223 3152518 R identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase, menaquinone-specific complement(3151223..3152518) Escherichia coli O157:H7 str. EC4115 6971074 YP_002271679.1 CDS ECH74115_3408 NC_011353.1 3152597 3152902 R identified by match to protein family HMM PF05957; hypothetical protein complement(3152597..3152902) Escherichia coli O157:H7 str. EC4115 6971870 YP_002271680.1 CDS ECH74115_3409 NC_011353.1 3152957 3153418 R identified by match to protein family HMM PF00583; hypothetical protein complement(3152957..3153418) Escherichia coli O157:H7 str. EC4115 6969499 YP_002271681.1 CDS rnz NC_011353.1 3153465 3154400 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 3153465..3154400 Escherichia coli O157:H7 str. EC4115 6968521 YP_002271682.1 CDS ECH74115_3411 NC_011353.1 3154468 3154587 R hypothetical protein complement(3154468..3154587) Escherichia coli O157:H7 str. EC4115 6969318 YP_002271683.1 CDS ECH74115_3412 NC_011353.1 3154591 3155811 D ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 3154591..3155811 Escherichia coli O157:H7 str. EC4115 6966932 YP_002271684.1 CDS ECH74115_3414 NC_011353.1 3156943 3157446 D identified by match to protein family HMM PF08974; hypothetical protein 3156943..3157446 Escherichia coli O157:H7 str. EC4115 6971014 YP_002271685.1 CDS nuoN NC_011353.1 3157513 3158970 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(3157513..3158970) Escherichia coli O157:H7 str. EC4115 6971170 YP_002271686.1 CDS nuoM NC_011353.1 3158977 3160506 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(3158977..3160506) Escherichia coli O157:H7 str. EC4115 6967673 YP_002271687.1 CDS nuoL NC_011353.1 3160737 3162572 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(3160737..3162572) Escherichia coli O157:H7 str. EC4115 6966999 YP_002271688.1 CDS nuoK NC_011353.1 3162575 3162877 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(3162575..3162877) Escherichia coli O157:H7 str. EC4115 6969312 YP_002271689.1 CDS nuoJ NC_011353.1 3162874 3163428 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(3162874..3163428) Escherichia coli O157:H7 str. EC4115 6968698 YP_002271690.1 CDS nuoI NC_011353.1 3163440 3163982 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(3163440..3163982) Escherichia coli O157:H7 str. EC4115 6968082 YP_002271691.1 CDS nuoH NC_011353.1 3163997 3164974 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(3163997..3164974) Escherichia coli O157:H7 str. EC4115 6970282 YP_002271692.1 CDS nuoG NC_011353.1 3164971 3167697 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(3164971..3167697) Escherichia coli O157:H7 str. EC4115 6970881 YP_002271693.1 CDS nuoF NC_011353.1 3167750 3169087 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(3167750..3169087) Escherichia coli O157:H7 str. EC4115 6967592 YP_002271694.1 CDS nuoE NC_011353.1 3169084 3169584 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(3169084..3169584) Escherichia coli O157:H7 str. EC4115 6966816 YP_002271695.1 CDS nuoC NC_011353.1 3169587 3171389 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; NADH:ubiquinone oxidoreductase subunit C/D complement(3169587..3171389) Escherichia coli O157:H7 str. EC4115 6970510 YP_002271696.1 CDS ECH74115_3426 NC_011353.1 3171483 3172145 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(3171483..3172145) Escherichia coli O157:H7 str. EC4115 6969851 YP_002271697.1 CDS nuoA NC_011353.1 3172161 3172604 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(3172161..3172604) Escherichia coli O157:H7 str. EC4115 6972104 YP_002271698.1 CDS lrhA NC_011353.1 3173235 3174173 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator LrhA complement(3173235..3174173) Escherichia coli O157:H7 str. EC4115 6971473 YP_002271699.1 CDS ECH74115_3429 NC_011353.1 3175093 3176310 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 3175093..3176310 Escherichia coli O157:H7 str. EC4115 6967894 YP_002271700.1 CDS yfbR NC_011353.1 3176394 3176993 D identified by match to protein family HMM PF01966; hypothetical protein 3176394..3176993 Escherichia coli O157:H7 str. EC4115 6966613 YP_002271701.1 CDS ECH74115_3431 NC_011353.1 3177052 3178884 R identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808; TRAP transporter DctM-like membrane protein complement(3177052..3178884) Escherichia coli O157:H7 str. EC4115 6968827 YP_002271702.1 CDS yfbT NC_011353.1 3178971 3179621 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; phosphatase complement(3178971..3179621) Escherichia coli O157:H7 str. EC4115 6969739 YP_002271703.1 CDS ECH74115_3433 NC_011353.1 3179632 3180126 R identified by match to protein family HMM PF03887; hypothetical protein complement(3179632..3180126) Escherichia coli O157:H7 str. EC4115 6971569 YP_002271704.1 CDS ECH74115_3434 NC_011353.1 3180209 3180664 R identified by match to protein family HMM PF04217; hypothetical protein complement(3180209..3180664) Escherichia coli O157:H7 str. EC4115 6970926 YP_002271705.1 CDS ackA NC_011353.1 3181002 3182204 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 3181002..3182204 Escherichia coli O157:H7 str. EC4115 6968225 YP_002271706.1 CDS pta NC_011353.1 3182279 3184423 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 3182279..3184423 Escherichia coli O157:H7 str. EC4115 6969032 YP_002271707.1 CDS ECH74115_3438 NC_011353.1 3184592 3186133 D identified by match to protein family HMM PF03606; hypothetical protein 3184592..3186133 Escherichia coli O157:H7 str. EC4115 6969510 YP_002271708.1 CDS ECH74115_3439 NC_011353.1 3186166 3186708 R identified by match to protein family HMM PF00293; NUDIX family hydrolase complement(3186166..3186708) Escherichia coli O157:H7 str. EC4115 6970316 YP_002271709.1 CDS ECH74115_3440 NC_011353.1 3186766 3187317 R identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase complement(3186766..3187317) Escherichia coli O157:H7 str. EC4115 6972180 YP_002271710.1 CDS ECH74115_3441 NC_011353.1 3187373 3188017 R identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein complement(3187373..3188017) Escherichia coli O157:H7 str. EC4115 6971698 YP_002271711.1 CDS ECH74115_3442 NC_011353.1 3188153 3188800 D identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 3188153..3188800 Escherichia coli O157:H7 str. EC4115 6968917 YP_002271712.1 CDS folX NC_011353.1 3188857 3189219 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 3188857..3189219 Escherichia coli O157:H7 str. EC4115 6969911 YP_002271713.1 CDS ECH74115_3444 NC_011353.1 3189240 3190133 D identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777; NAD dependent epimerase/dehydratase family protein 3189240..3190133 Escherichia coli O157:H7 str. EC4115 6970258 YP_002271714.1 CDS ECH74115_3445 NC_011353.1 3190181 3191071 R identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein complement(3190181..3191071) Escherichia coli O157:H7 str. EC4115 6971833 YP_002271715.1 CDS hisP NC_011353.1 3191268 3192041 R identified by match to protein family HMM PF00005; histidine/lysine/arginine/ornithine transporter subunit complement(3191268..3192041) Escherichia coli O157:H7 str. EC4115 6966896 YP_002271716.1 CDS hisM NC_011353.1 3192049 3192765 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisM complement(3192049..3192765) Escherichia coli O157:H7 str. EC4115 6967486 YP_002271717.1 CDS hisQ NC_011353.1 3192762 3193448 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisQ complement(3192762..3193448) Escherichia coli O157:H7 str. EC4115 6969358 YP_002271718.1 CDS hisJ NC_011353.1 3193538 3194320 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; histidine ABC transporter periplasmic histidine-binding protein complement(3193538..3194320) Escherichia coli O157:H7 str. EC4115 6969822 YP_002271719.1 CDS argT NC_011353.1 3194541 3195323 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; lysine-arginine-ornithine-binding periplasmic protein complement(3194541..3195323) Escherichia coli O157:H7 str. EC4115 6969556 YP_002271720.1 CDS ubiX NC_011353.1 3195589 3196158 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(3195589..3196158) Escherichia coli O157:H7 str. EC4115 6970209 YP_002271721.1 CDS purF NC_011353.1 3196253 3197770 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(3196253..3197770) Escherichia coli O157:H7 str. EC4115 6968436 YP_002271722.1 CDS cvpA NC_011353.1 3197807 3198295 R membrane protein required for colicin V production; colicin V production protein complement(3197807..3198295) Escherichia coli O157:H7 str. EC4115 6968188 YP_002271723.1 CDS ECH74115_3454 NC_011353.1 3198827 3199489 R identified by match to protein family HMM PF05036; hypothetical protein complement(3198827..3199489) Escherichia coli O157:H7 str. EC4115 6969927 YP_002271724.1 CDS folC NC_011353.1 3199479 3200747 R identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; bifunctional folylpolyglutamate synthase/dihydrofolate synthase complement(3199479..3200747) Escherichia coli O157:H7 str. EC4115 6972127 YP_002271725.1 CDS accD NC_011353.1 3200817 3201731 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(3200817..3201731) Escherichia coli O157:H7 str. EC4115 6969890 YP_002271726.1 CDS ECH74115_3457 NC_011353.1 3201887 3202546 R identified by match to protein family HMM PF09335; hypothetical protein complement(3201887..3202546) Escherichia coli O157:H7 str. EC4115 6970522 YP_002271727.1 CDS truA NC_011353.1 3202629 3203441 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(3202629..3203441) Escherichia coli O157:H7 str. EC4115 6970479 YP_002271728.1 CDS ECH74115_3459 NC_011353.1 3203441 3204454 R identified by match to protein family HMM PF01118; match to protein family HMM PF02774; semialdehyde dehydrogenase complement(3203441..3204454) Escherichia coli O157:H7 str. EC4115 6968237 YP_002271729.1 CDS ECH74115_3461 NC_011353.1 3204435 3204548 D identified by glimmer; hypothetical protein 3204435..3204548 Escherichia coli O157:H7 str. EC4115 6968860 YP_002271730.1 CDS pdxB NC_011353.1 3204520 3205656 R identified by match to protein family HMM PF00389; match to protein family HMM PF02826; erythronate-4-phosphate dehydrogenase complement(3204520..3205656) Escherichia coli O157:H7 str. EC4115 6966575 YP_002271731.1 CDS flk NC_011353.1 3205755 3206750 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 3205755..3206750 Escherichia coli O157:H7 str. EC4115 6966640 YP_002271732.1 CDS ECH74115_3462 NC_011353.1 3206747 3207925 R identified by match to protein family HMM PF07690; hypothetical protein complement(3206747..3207925) Escherichia coli O157:H7 str. EC4115 6972110 YP_002271733.1 CDS fabB NC_011353.1 3208200 3209420 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(3208200..3209420) Escherichia coli O157:H7 str. EC4115 6971480 YP_002271734.1 CDS mnmC NC_011353.1 3209579 3211585 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 3209579..3211585 Escherichia coli O157:H7 str. EC4115 6970260 YP_002271735.1 CDS ECH74115_3466 NC_011353.1 3211706 3211984 R identified by match to protein family HMM PF08891; hypothetical protein complement(3211706..3211984) Escherichia coli O157:H7 str. EC4115 6969460 YP_002271736.1 CDS ECH74115_3467 NC_011353.1 3212018 3212566 R identified by match to protein family HMM PF04315; hypothetical protein complement(3212018..3212566) Escherichia coli O157:H7 str. EC4115 6969021 YP_002271737.1 CDS ECH74115_3468 NC_011353.1 3212566 3213375 R identified by match to protein family HMM PF01925; hypothetical protein complement(3212566..3213375) Escherichia coli O157:H7 str. EC4115 6967521 YP_002271738.1 CDS mepA NC_011353.1 3213375 3214199 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(3213375..3214199) Escherichia coli O157:H7 str. EC4115 6967741 YP_002271739.1 CDS aroC NC_011353.1 3214203 3215288 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(3214203..3215288) Escherichia coli O157:H7 str. EC4115 6966953 YP_002271740.1 CDS prmB NC_011353.1 3215323 3216255 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(3215323..3216255) Escherichia coli O157:H7 str. EC4115 6972237 YP_002271741.1 CDS ECH74115_3472 NC_011353.1 3216421 3216972 D identified by match to protein family HMM PF01713; hypothetical protein 3216421..3216972 Escherichia coli O157:H7 str. EC4115 6971640 YP_002271742.1 CDS ECH74115_3473 NC_011353.1 3217143 3217985 R hypothetical protein complement(3217143..3217985) Escherichia coli O157:H7 str. EC4115 6970984 YP_002271743.1 CDS ECH74115_3474 NC_011353.1 3217987 3218508 R identified by match to protein family HMM PF00419; fimbrial protein complement(3217987..3218508) Escherichia coli O157:H7 str. EC4115 6970154 YP_002271744.1 CDS ECH74115_3475 NC_011353.1 3218741 3218914 R minor fimbrial subunit complement(3218741..3218914) Escherichia coli O157:H7 str. EC4115 6969566 YP_002271745.1 CDS ECH74115_3476 NC_011353.1 3218911 3219360 R fimbrial subunit complement(3218911..3219360) Escherichia coli O157:H7 str. EC4115 6970482 YP_002271746.1 CDS ECH74115_3477 NC_011353.1 3219378 3219644 R fimbrial protein complement(3219378..3219644) Escherichia coli O157:H7 str. EC4115 6968608 YP_002271747.1 CDS ECH74115_3478 NC_011353.1 3219712 3219867 D identified by glimmer; hypothetical protein 3219712..3219867 Escherichia coli O157:H7 str. EC4115 6969209 YP_002271748.1 CDS ECH74115_3479 NC_011353.1 3219889 3220647 R identified by match to protein family HMM PF00345; chaperone protein PapD complement(3219889..3220647) Escherichia coli O157:H7 str. EC4115 6968728 YP_002271749.1 CDS ECH74115_3480 NC_011353.1 3220670 3223252 R identified by match to protein family HMM PF00577; fimbrial usher protein complement(3220670..3223252) Escherichia coli O157:H7 str. EC4115 6966571 YP_002271750.1 CDS ECH74115_3481 NC_011353.1 3223391 3223954 R identified by match to protein family HMM PF00419; fimbrial protein complement(3223391..3223954) Escherichia coli O157:H7 str. EC4115 6967475 YP_002271751.1 CDS sixA NC_011353.1 3224600 3225085 R identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249; phosphohistidine phosphatase complement(3224600..3225085) Escherichia coli O157:H7 str. EC4115 6969731 YP_002271752.1 CDS ECH74115_3483 NC_011353.1 3225062 3225214 D identified by glimmer; hypothetical protein 3225062..3225214 Escherichia coli O157:H7 str. EC4115 6970331 YP_002271753.1 CDS fadJ NC_011353.1 3225288 3227432 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(3225288..3227432) Escherichia coli O157:H7 str. EC4115 6968359 YP_002271754.1 CDS fadI NC_011353.1 3227432 3228742 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(3227432..3228742) Escherichia coli O157:H7 str. EC4115 6972054 YP_002271755.1 CDS ECH74115_3486 NC_011353.1 3228922 3229206 R identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein complement(3228922..3229206) Escherichia coli O157:H7 str. EC4115 6971623 YP_002271756.1 CDS ECH74115_3487 NC_011353.1 3229578 3230918 D identified by match to protein family HMM PF03349; long-chain fatty acid outer membrane transporter 3229578..3230918 Escherichia coli O157:H7 str. EC4115 6966853 YP_002271757.1 CDS ECH74115_3489 NC_011353.1 3232388 3232504 D identified by glimmer; hypothetical protein 3232388..3232504 Escherichia coli O157:H7 str. EC4115 6969145 YP_002271758.1 CDS ECH74115_3490 NC_011353.1 3232709 3233464 R identified by match to protein family HMM PF04333; lipoprotein, VacJ family complement(3232709..3233464) Escherichia coli O157:H7 str. EC4115 6969549 YP_002271759.1 CDS ECH74115_3492 NC_011353.1 3233758 3234690 D hypothetical protein 3233758..3234690 Escherichia coli O157:H7 str. EC4115 6969527 YP_002271760.1 CDS ECH74115_3494 NC_011353.1 3243356 3244621 R hypothetical protein complement(3243356..3244621) Escherichia coli O157:H7 str. EC4115 6971038 YP_002271761.1 CDS ECH74115_3495 NC_011353.1 3244632 3244925 R hypothetical protein complement(3244632..3244925) Escherichia coli O157:H7 str. EC4115 6971064 YP_002271762.1 CDS ECH74115_3496 NC_011353.1 3244935 3245381 R hypothetical protein complement(3244935..3245381) Escherichia coli O157:H7 str. EC4115 6968943 YP_002271763.1 CDS ECH74115_3497 NC_011353.1 3245384 3246040 R hypothetical protein complement(3245384..3246040) Escherichia coli O157:H7 str. EC4115 6969420 YP_002271764.1 CDS ECH74115_3498 NC_011353.1 3246135 3246512 R hypothetical protein complement(3246135..3246512) Escherichia coli O157:H7 str. EC4115 6968658 YP_002271765.1 CDS ECH74115_3499 NC_011353.1 3246593 3246733 R hypothetical protein complement(3246593..3246733) Escherichia coli O157:H7 str. EC4115 6969260 YP_002271766.1 CDS ECH74115_3500 NC_011353.1 3246964 3247698 R identified by match to protein family HMM PF06316; outer membrane protein Lom complement(3246964..3247698) Escherichia coli O157:H7 str. EC4115 6967015 YP_002271767.1 CDS ECH74115_3502 NC_011353.1 3248412 3248690 R outer membrane protein complement(3248412..3248690) Escherichia coli O157:H7 str. EC4115 6971300 YP_002271768.1 CDS ECH74115_3503 NC_011353.1 3248705 3249919 R hypothetical protein complement(3248705..3249919) Escherichia coli O157:H7 str. EC4115 6971922 YP_002271769.1 CDS ECH74115_3504 NC_011353.1 3249970 3251595 R hypothetical protein complement(3249970..3251595) Escherichia coli O157:H7 str. EC4115 6971614 YP_002271770.1 CDS ECH74115_3505 NC_011353.1 3251710 3251823 R identified by glimmer; hypothetical protein complement(3251710..3251823) Escherichia coli O157:H7 str. EC4115 6971193 YP_002271771.1 CDS ECH74115_3507 NC_011353.1 3252217 3252486 R identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein complement(3252217..3252486) Escherichia coli O157:H7 str. EC4115 6969622 YP_002271772.1 CDS ECH74115_3508 NC_011353.1 3252488 3254425 R identified by match to protein family HMM PF01391; match to protein family HMM PF03406; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein complement(3252488..3254425) Escherichia coli O157:H7 str. EC4115 6967267 YP_002271773.1 CDS ECH74115_3509 NC_011353.1 3254422 3255072 R hypothetical protein complement(3254422..3255072) Escherichia coli O157:H7 str. EC4115 6970008 YP_002271774.1 CDS ECH74115_3510 NC_011353.1 3255072 3255635 R hypothetical protein complement(3255072..3255635) Escherichia coli O157:H7 str. EC4115 6968116 YP_002271775.1 CDS ECH74115_3511 NC_011353.1 3255619 3256080 R hypothetical protein complement(3255619..3256080) Escherichia coli O157:H7 str. EC4115 6968688 YP_002271776.1 CDS ECH74115_3512 NC_011353.1 3256130 3256519 R hypothetical protein complement(3256130..3256519) Escherichia coli O157:H7 str. EC4115 6966604 YP_002271777.1 CDS ECH74115_3513 NC_011353.1 3256575 3257789 R hypothetical protein complement(3256575..3257789) Escherichia coli O157:H7 str. EC4115 6967387 YP_002271778.1 CDS ECH74115_3514 NC_011353.1 3257813 3258229 R hypothetical protein complement(3257813..3258229) Escherichia coli O157:H7 str. EC4115 6971478 YP_002271779.1 CDS ECH74115_3515 NC_011353.1 3258360 3258686 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 3258360..3258686 Escherichia coli O157:H7 str. EC4115 6971724 YP_002271780.1 CDS ECH74115_3516 NC_011353.1 3258683 3259573 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 3258683..3259573 Escherichia coli O157:H7 str. EC4115 6971127 YP_002271781.1 CDS ECH74115_3517 NC_011353.1 3259576 3260133 R hypothetical protein complement(3259576..3260133) Escherichia coli O157:H7 str. EC4115 6970147 YP_002271782.1 CDS ECH74115_3518 NC_011353.1 3260291 3262435 R identified by glimmer; hypothetical protein complement(3260291..3262435) Escherichia coli O157:H7 str. EC4115 6969513 YP_002271783.1 CDS ECH74115_3519 NC_011353.1 3262435 3264141 R large subunit terminase complement(3262435..3264141) Escherichia coli O157:H7 str. EC4115 6969320 YP_002271784.1 CDS ECH74115_3520 NC_011353.1 3264122 3264928 R hypothetical protein complement(3264122..3264928) Escherichia coli O157:H7 str. EC4115 6968364 YP_002271785.1 CDS ECH74115_3521 NC_011353.1 3264984 3265097 R hypothetical protein complement(3264984..3265097) Escherichia coli O157:H7 str. EC4115 6967344 YP_002271786.1 CDS ECH74115_3522 NC_011353.1 3265337 3265630 D identified by match to protein family HMM PF06291; Bor protein 3265337..3265630 Escherichia coli O157:H7 str. EC4115 6971512 YP_002271787.1 CDS ECH74115_3523 NC_011353.1 3265662 3266126 R identified by match to protein family HMM PF03245; bacteriophage lysis protein complement(3265662..3266126) Escherichia coli O157:H7 str. EC4115 6970885 YP_002271788.1 CDS ECH74115_3524 NC_011353.1 3266134 3266268 R hypothetical protein complement(3266134..3266268) Escherichia coli O157:H7 str. EC4115 6972021 YP_002271789.1 CDS ECH74115_3525 NC_011353.1 3266283 3266852 R anti-repressor protein Ant complement(3266283..3266852) Escherichia coli O157:H7 str. EC4115 6971506 YP_002271790.1 CDS ECH74115_3526 NC_011353.1 3267126 3267659 R identified by match to protein family HMM PF00959; lysozyme complement(3267126..3267659) Escherichia coli O157:H7 str. EC4115 6970701 YP_002271791.1 CDS ECH74115_3527 NC_011353.1 3267664 3267879 R identified by match to protein family HMM PF04971; hypothetical protein complement(3267664..3267879) Escherichia coli O157:H7 str. EC4115 6968821 YP_002271792.1 CDS ECH74115_3528 NC_011353.1 3267956 3268228 R identified by match to protein family HMM PF05696; hypothetical protein complement(3267956..3268228) Escherichia coli O157:H7 str. EC4115 6967994 YP_002271793.1 CDS ECH74115_3529 NC_011353.1 3268269 3268448 R identified by match to protein family HMM PF07125; hypothetical protein complement(3268269..3268448) Escherichia coli O157:H7 str. EC4115 6967254 YP_002271794.1 CDS ECH74115_3530 NC_011353.1 3268461 3268586 R hypothetical protein complement(3268461..3268586) Escherichia coli O157:H7 str. EC4115 6966808 YP_002271795.1 CDS ECH74115_3531 NC_011353.1 3268583 3270520 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(3268583..3270520) Escherichia coli O157:H7 str. EC4115 6971709 YP_002271796.1 CDS ECH74115_3532 NC_011353.1 3271007 3271276 R identified by match to protein family HMM PF02258; shiga toxin 2 B subunit complement(3271007..3271276) Escherichia coli O157:H7 str. EC4115 6969893 YP_002271797.1 CDS ECH74115_3533 NC_011353.1 3271288 3272247 R identified by match to protein family HMM PF00161; shiga toxin subunit A complement(3271288..3272247) Escherichia coli O157:H7 str. EC4115 6968153 YP_002271798.1 CDS ECH74115_3538 NC_011353.1 3273029 3273220 R antitermination protein complement(3273029..3273220) Escherichia coli O157:H7 str. EC4115 6967616 YP_002271799.1 CDS ECH74115_3539 NC_011353.1 3273200 3273343 D identified by glimmer; hypothetical protein 3273200..3273343 Escherichia coli O157:H7 str. EC4115 6968649 YP_002271800.1 CDS ECH74115_3540 NC_011353.1 3273456 3273650 R identified by match to protein family HMM PF06322; hypothetical protein complement(3273456..3273650) Escherichia coli O157:H7 str. EC4115 6969253 YP_002271801.1 CDS ECH74115_3541 NC_011353.1 3273647 3274252 R identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein complement(3273647..3274252) Escherichia coli O157:H7 str. EC4115 6968767 YP_002271802.1 CDS ECH74115_3542 NC_011353.1 3274252 3274974 R identified by match to protein family HMM PF03374; DNA-binding protein Roi complement(3274252..3274974) Escherichia coli O157:H7 str. EC4115 6969408 YP_002271803.1 CDS ECH74115_3543 NC_011353.1 3275136 3275537 R hypothetical protein complement(3275136..3275537) Escherichia coli O157:H7 str. EC4115 6970339 YP_002271804.1 CDS ECH74115_3544 NC_011353.1 3275612 3276286 R hypothetical protein complement(3275612..3276286) Escherichia coli O157:H7 str. EC4115 6970907 YP_002271805.1 CDS ECH74115_3545 NC_011353.1 3276734 3277261 R identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712; phage N-6-adenine-methyltransferase complement(3276734..3277261) Escherichia coli O157:H7 str. EC4115 6969941 YP_002271806.1 CDS ECH74115_3546 NC_011353.1 3277287 3277406 R identified by glimmer; hypothetical protein complement(3277287..3277406) Escherichia coli O157:H7 str. EC4115 6969293 YP_002271807.1 CDS ECH74115_3547 NC_011353.1 3278135 3278248 D identified by glimmer; hypothetical protein 3278135..3278248 Escherichia coli O157:H7 str. EC4115 6967973 YP_002271808.1 CDS ECH74115_3548 NC_011353.1 3278250 3278432 R hypothetical protein complement(3278250..3278432) Escherichia coli O157:H7 str. EC4115 6968831 YP_002271809.1 CDS ECH74115_3550 NC_011353.1 3278791 3279069 R hypothetical protein complement(3278791..3279069) Escherichia coli O157:H7 str. EC4115 6970062 YP_002271810.1 CDS ECH74115_3551 NC_011353.1 3279140 3279430 R Ren protein complement(3279140..3279430) Escherichia coli O157:H7 str. EC4115 6970467 YP_002271811.1 CDS ECH74115_3552 NC_011353.1 3279427 3280128 R identified by match to protein family HMM PF06992; replication protein P complement(3279427..3280128) Escherichia coli O157:H7 str. EC4115 6971301 YP_002271812.1 CDS ECH74115_3553 NC_011353.1 3280125 3281063 R identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; replication protein O complement(3280125..3281063) Escherichia coli O157:H7 str. EC4115 6971743 YP_002271813.1 CDS ECH74115_3554 NC_011353.1 3281096 3281392 R identified by match to protein family HMM PF05269; bacteriophage CII protein complement(3281096..3281392) Escherichia coli O157:H7 str. EC4115 6966719 YP_002271814.1 CDS ECH74115_3555 NC_011353.1 3281531 3281758 R hypothetical protein complement(3281531..3281758) Escherichia coli O157:H7 str. EC4115 6968668 YP_002271815.1 CDS ECH74115_3556 NC_011353.1 3281837 3282544 D identified by match to protein family HMM PF00717; match to protein family HMM PF01381; repressor protein CI 3281837..3282544 Escherichia coli O157:H7 str. EC4115 6969627 YP_002271816.1 CDS ECH74115_3557 NC_011353.1 3282605 3282946 D hypothetical protein 3282605..3282946 Escherichia coli O157:H7 str. EC4115 6969856 YP_002271817.1 CDS ECH74115_3558 NC_011353.1 3283469 3284515 D identified by match to protein family HMM PF00069; serine/threonine kinase 3283469..3284515 Escherichia coli O157:H7 str. EC4115 6970460 YP_002271818.1 CDS ECH74115_3559 NC_011353.1 3285171 3285554 D antitermination protein N 3285171..3285554 Escherichia coli O157:H7 str. EC4115 6971434 YP_002271819.1 CDS ECH74115_3560 NC_011353.1 3285613 3286083 D identified by glimmer; hypothetical protein 3285613..3286083 Escherichia coli O157:H7 str. EC4115 6969525 YP_002271820.1 CDS ECH74115_3561 NC_011353.1 3286234 3286602 D identified by glimmer; hypothetical protein 3286234..3286602 Escherichia coli O157:H7 str. EC4115 6966701 YP_002271821.1 CDS ECH74115_3562 NC_011353.1 3286808 3286972 D lambda Kil 3286808..3286972 Escherichia coli O157:H7 str. EC4115 6967317 YP_002271822.1 CDS gam NC_011353.1 3287027 3287323 D identified by match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 3287027..3287323 Escherichia coli O157:H7 str. EC4115 6968286 YP_002271823.1 CDS bet NC_011353.1 3287329 3288114 D identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 3287329..3288114 Escherichia coli O157:H7 str. EC4115 6968868 YP_002271824.1 CDS exo NC_011353.1 3288111 3288791 D identified by match to protein family HMM PF09588; exonuclease 3288111..3288791 Escherichia coli O157:H7 str. EC4115 6970491 YP_002271825.1 CDS ECH74115_3566 NC_011353.1 3289021 3289134 D hypothetical protein 3289021..3289134 Escherichia coli O157:H7 str. EC4115 6968406 YP_002271826.1 CDS ECH74115_3567 NC_011353.1 3289211 3289426 D hypothetical protein 3289211..3289426 Escherichia coli O157:H7 str. EC4115 6970208 YP_002271827.1 CDS ECH74115_3568 NC_011353.1 3289743 3290690 D identified by match to protein family HMM PF04447; hypothetical protein 3289743..3290690 Escherichia coli O157:H7 str. EC4115 6970920 YP_002271828.1 CDS ECH74115_3569 NC_011353.1 3290692 3291198 D bacteriophage protein 3290692..3291198 Escherichia coli O157:H7 str. EC4115 6967241 YP_002271829.1 CDS ECH74115_3570 NC_011353.1 3291158 3291373 D hypothetical protein 3291158..3291373 Escherichia coli O157:H7 str. EC4115 6967842 YP_002271830.1 CDS ECH74115_3571 NC_011353.1 3291375 3291593 D hypothetical protein 3291375..3291593 Escherichia coli O157:H7 str. EC4115 6968456 YP_002271831.1 CDS ECH74115_3572 NC_011353.1 3291595 3291882 D hypothetical protein 3291595..3291882 Escherichia coli O157:H7 str. EC4115 6969061 YP_002271832.1 CDS ECH74115_3574 NC_011353.1 3293113 3293766 D identified by match to protein family HMM PF08346; phage anti-repressor protein AntB 3293113..3293766 Escherichia coli O157:H7 str. EC4115 6969896 YP_002271833.1 CDS ECH74115_3575 NC_011353.1 3293809 3293976 D hypothetical protein 3293809..3293976 Escherichia coli O157:H7 str. EC4115 6969694 YP_002271834.1 CDS ECH74115_3576 NC_011353.1 3294203 3294829 D identified by match to protein family HMM PF05063; adenine methylase 3294203..3294829 Escherichia coli O157:H7 str. EC4115 6970354 YP_002271835.1 CDS ECH74115_3577 NC_011353.1 3294789 3295001 D hypothetical protein 3294789..3295001 Escherichia coli O157:H7 str. EC4115 6972169 YP_002271836.1 CDS ECH74115_3578 NC_011353.1 3295037 3295414 D hypothetical protein 3295037..3295414 Escherichia coli O157:H7 str. EC4115 6970817 YP_002271837.1 CDS ECH74115_3580 NC_011353.1 3295493 3295675 D hypothetical protein 3295493..3295675 Escherichia coli O157:H7 str. EC4115 6970637 YP_002271838.1 CDS ECH74115_3579 NC_011353.1 3295659 3296828 R identified by match to protein family HMM PF00589; integrase complement(3295659..3296828) Escherichia coli O157:H7 str. EC4115 6968897 YP_002271839.1 CDS ECH74115_3582 NC_011353.1 3297224 3298417 D identified by match to protein family HMM PF00589; integrase 3297224..3298417 Escherichia coli O157:H7 str. EC4115 6972415 YP_002271840.1 CDS ECH74115_3583 NC_011353.1 3298592 3299728 R DNA injection protein complement(3298592..3299728) Escherichia coli O157:H7 str. EC4115 6968249 YP_002271841.1 CDS ECH74115_3584 NC_011353.1 3299738 3300364 R DNA transfer protein complement(3299738..3300364) Escherichia coli O157:H7 str. EC4115 6967282 YP_002271842.1 CDS ECH74115_3585 NC_011353.1 3300405 3300872 R hypothetical protein complement(3300405..3300872) Escherichia coli O157:H7 str. EC4115 6966695 YP_002271843.1 CDS ECH74115_3586 NC_011353.1 3300872 3301402 R hypothetical protein complement(3300872..3301402) Escherichia coli O157:H7 str. EC4115 6971443 YP_002271844.1 CDS ECH74115_3587 NC_011353.1 3301424 3302119 D replication protein 3301424..3302119 Escherichia coli O157:H7 str. EC4115 6967727 YP_002271845.1 CDS ECH74115_3588 NC_011353.1 3302789 3304201 R hypothetical protein complement(3302789..3304201) Escherichia coli O157:H7 str. EC4115 6968961 YP_002271846.1 CDS ECH74115_3589 NC_011353.1 3304388 3304564 R hypothetical protein complement(3304388..3304564) Escherichia coli O157:H7 str. EC4115 6966918 YP_002271847.1 CDS ECH74115_3590 NC_011353.1 3304867 3305493 D resolvase domain-containing protein 3304867..3305493 Escherichia coli O157:H7 str. EC4115 6970600 YP_002271848.1 CDS cscK NC_011353.1 3307410 3308324 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(3307410..3308324) Escherichia coli O157:H7 str. EC4115 6971474 YP_002271849.1 CDS ECH74115_3593 NC_011353.1 3308415 3308576 R identified by glimmer; hypothetical protein complement(3308415..3308576) Escherichia coli O157:H7 str. EC4115 6972118 YP_002271850.1 CDS ECH74115_3594 NC_011353.1 3308531 3309973 D identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 3308531..3309973 Escherichia coli O157:H7 str. EC4115 6968510 YP_002271851.1 CDS ECH74115_3595 NC_011353.1 3309981 3310976 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar binding transcriptional regulator, LacI family complement(3309981..3310976) Escherichia coli O157:H7 str. EC4115 6970845 YP_002271852.1 CDS ECH74115_3596 NC_011353.1 3311219 3311437 D identified by glimmer; hypothetical protein 3311219..3311437 Escherichia coli O157:H7 str. EC4115 6966967 YP_002271853.1 CDS dsdA NC_011353.1 3311455 3312783 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 3311455..3312783 Escherichia coli O157:H7 str. EC4115 6967579 YP_002271854.1 CDS emrY NC_011353.1 3312891 3314429 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; multidrug resistance protein Y complement(3312891..3314429) Escherichia coli O157:H7 str. EC4115 6967306 YP_002271855.1 CDS emrK NC_011353.1 3314429 3315592 R identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998; drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK complement(3314429..3315592) Escherichia coli O157:H7 str. EC4115 6972239 YP_002271856.1 CDS evgA NC_011353.1 3316008 3316622 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 3316008..3316622 Escherichia coli O157:H7 str. EC4115 6968992 YP_002271857.1 CDS evgS NC_011353.1 3316837 3320220 D identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518; hybrid sensory histidine kinase in two-component regulatory system with EvgA 3316837..3320220 Escherichia coli O157:H7 str. EC4115 6968179 YP_002271858.1 CDS ECH74115_3604 NC_011353.1 3321491 3322435 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(3321491..3322435) Escherichia coli O157:H7 str. EC4115 6971844 YP_002271859.1 CDS oxc NC_011353.1 3322505 3324199 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(3322505..3324199) Escherichia coli O157:H7 str. EC4115 6971322 YP_002271860.1 CDS frc NC_011353.1 3324253 3325503 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(3324253..3325503) Escherichia coli O157:H7 str. EC4115 6970697 YP_002271861.1 CDS ECH74115_3607 NC_011353.1 3326016 3326651 R hypothetical protein complement(3326016..3326651) Escherichia coli O157:H7 str. EC4115 6970089 YP_002271862.1 CDS ECH74115_3608 NC_011353.1 3327299 3327541 R hypothetical protein complement(3327299..3327541) Escherichia coli O157:H7 str. EC4115 6969051 YP_002271863.1 CDS ECH74115_3609 NC_011353.1 3327894 3328814 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 3327894..3328814 Escherichia coli O157:H7 str. EC4115 6968348 YP_002271864.1 CDS ECH74115_3610 NC_011353.1 3329125 3329241 D identified by glimmer; hypothetical protein 3329125..3329241 Escherichia coli O157:H7 str. EC4115 6969491 YP_002271865.1 CDS ECH74115_3611 NC_011353.1 3329306 3330544 R identified by match to protein family HMM PF00155; aminotransferase complement(3329306..3330544) Escherichia coli O157:H7 str. EC4115 6968879 YP_002271866.1 CDS ECH74115_3612 NC_011353.1 3330939 3332618 D identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 3330939..3332618 Escherichia coli O157:H7 str. EC4115 6971602 YP_002271867.1 CDS ECH74115_3613 NC_011353.1 3332633 3333367 D identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 3332633..3333367 Escherichia coli O157:H7 str. EC4115 6970833 YP_002271868.1 CDS ECH74115_3614 NC_011353.1 3333380 3334237 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3333380..3334237 Escherichia coli O157:H7 str. EC4115 6967812 YP_002271869.1 CDS fryA NC_011353.1 3334240 3336735 R identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417; multiphosphoryl transfer protein 1 complement(3334240..3336735) Escherichia coli O157:H7 str. EC4115 6967029 YP_002271870.1 CDS ECH74115_3616 NC_011353.1 3336760 3337797 R metalloprotein; exoaminopeptidase complement(3336760..3337797) Escherichia coli O157:H7 str. EC4115 6967379 YP_002271871.1 CDS ypdF NC_011353.1 3337797 3338882 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(3337797..3338882) Escherichia coli O157:H7 str. EC4115 6966630 YP_002271872.1 CDS fryC NC_011353.1 3338897 3340144 R identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system fructose-like transporter subunit IIC complement(3338897..3340144) Escherichia coli O157:H7 str. EC4115 6968089 YP_002271873.1 CDS ECH74115_3619 NC_011353.1 3340166 3340492 R identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829; PTS system fructose specific transporter subunit IIB complement(3340166..3340492) Escherichia coli O157:H7 str. EC4115 6967448 YP_002271874.1 CDS glk NC_011353.1 3340711 3341676 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(3340711..3341676) Escherichia coli O157:H7 str. EC4115 6966812 YP_002271875.1 CDS ECH74115_3621 NC_011353.1 3341880 3343136 D identified by match to protein family HMM PF00654; hypothetical protein 3341880..3343136 Escherichia coli O157:H7 str. EC4115 6968730 YP_002271876.1 CDS ECH74115_3622 NC_011353.1 3343251 3343577 D hypothetical protein 3343251..3343577 Escherichia coli O157:H7 str. EC4115 6968046 YP_002271877.1 CDS mntH NC_011353.1 3343717 3344955 R identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH complement(3343717..3344955) Escherichia coli O157:H7 str. EC4115 6970660 YP_002271878.1 CDS nupC NC_011353.1 3345291 3346493 D identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC 3345291..3346493 Escherichia coli O157:H7 str. EC4115 6970185 YP_002271879.1 CDS ECH74115_3625 NC_011353.1 3346543 3348732 R identified by match to protein family HMM PF00563; match to protein family HMM PF05231; diguanylate cyclase complement(3346543..3348732) Escherichia coli O157:H7 str. EC4115 6971926 YP_002271880.1 CDS ECH74115_3628 NC_011353.1 3349366 3349710 D identified by match to protein family HMM PF07037; hypothetical protein 3349366..3349710 Escherichia coli O157:H7 str. EC4115 6972359 YP_002271881.1 CDS ECH74115_3629 NC_011353.1 3349712 3350104 D identified by match to protein family HMM PF07037; hypothetical protein 3349712..3350104 Escherichia coli O157:H7 str. EC4115 6971135 YP_002271882.1 CDS ECH74115_3630 NC_011353.1 3350144 3351352 R identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; transposase, IS605 orfB family complement(3350144..3351352) Escherichia coli O157:H7 str. EC4115 6967253 YP_002271883.1 CDS ECH74115_3631 NC_011353.1 3351375 3351902 D identified by match to protein family HMM PF01797; transposase family protein 3351375..3351902 Escherichia coli O157:H7 str. EC4115 6971813 YP_002271884.1 CDS gltX NC_011353.1 3351903 3353318 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(3351903..3353318) Escherichia coli O157:H7 str. EC4115 6971039 YP_002271885.1 CDS ECH74115_3633 NC_011353.1 3353322 3353453 D identified by glimmer; hypothetical protein 3353322..3353453 Escherichia coli O157:H7 str. EC4115 6967025 YP_002271886.1 CDS ECH74115_3639 NC_011353.1 3354094 3354435 D identified by glimmer; hypothetical protein 3354094..3354435 Escherichia coli O157:H7 str. EC4115 6972437 YP_002271887.1 CDS ECH74115_3638 NC_011353.1 3354426 3355352 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(3354426..3355352) Escherichia coli O157:H7 str. EC4115 6967804 YP_002271888.1 CDS ECH74115_3641 NC_011353.1 3355442 3356440 D identified by match to protein family HMM PF01758; sodium:bile acid symporter family protein 3355442..3356440 Escherichia coli O157:H7 str. EC4115 6968024 YP_002271889.1 CDS ECH74115_3640 NC_011353.1 3356437 3356655 R hypothetical protein complement(3356437..3356655) Escherichia coli O157:H7 str. EC4115 6968676 YP_002271890.1 CDS ligA NC_011353.1 3356657 3358672 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(3356657..3358672) Escherichia coli O157:H7 str. EC4115 6969635 YP_002271891.1 CDS zipA NC_011353.1 3358743 3359741 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(3358743..3359741) Escherichia coli O157:H7 str. EC4115 6970557 YP_002271892.1 CDS cysZ NC_011353.1 3359971 3360732 D role in sulfur assimilation; sulfate transport protein CysZ 3359971..3360732 Escherichia coli O157:H7 str. EC4115 6971422 YP_002271893.1 CDS cysK NC_011353.1 3360917 3361888 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 3360917..3361888 Escherichia coli O157:H7 str. EC4115 6968650 YP_002271894.1 CDS ptsH NC_011353.1 3362272 3362529 D identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 3362272..3362529 Escherichia coli O157:H7 str. EC4115 6970555 YP_002271895.1 CDS ptsI NC_011353.1 3362574 3364301 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 3362574..3364301 Escherichia coli O157:H7 str. EC4115 6969889 YP_002271896.1 CDS crr NC_011353.1 3364342 3364851 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 3364342..3364851 Escherichia coli O157:H7 str. EC4115 6971744 YP_002271897.1 CDS pdxK NC_011353.1 3364894 3365745 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(3364894..3365745) Escherichia coli O157:H7 str. EC4115 6967439 YP_002271898.1 CDS cysM NC_011353.1 3366220 3367131 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(3366220..3367131) Escherichia coli O157:H7 str. EC4115 6968733 YP_002271899.1 CDS cysA NC_011353.1 3367265 3368362 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate/thiosulfate transporter subunit complement(3367265..3368362) Escherichia coli O157:H7 str. EC4115 6968118 YP_002271900.1 CDS cysW NC_011353.1 3368352 3369227 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(3368352..3369227) Escherichia coli O157:H7 str. EC4115 6969339 YP_002271901.1 CDS cysT NC_011353.1 3369227 3370060 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate/thiosulfate transporter subunit complement(3369227..3370060) Escherichia coli O157:H7 str. EC4115 6968183 YP_002271902.1 CDS cysP NC_011353.1 3370060 3371076 R identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; thiosulfate transporter subunit complement(3370060..3371076) Escherichia coli O157:H7 str. EC4115 6970512 YP_002271903.1 CDS ucpA NC_011353.1 3371234 3372025 R identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; short chain dehydrogenase complement(3371234..3372025) Escherichia coli O157:H7 str. EC4115 6970065 YP_002271904.1 CDS ECH74115_3657 NC_011353.1 3372154 3373011 R identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator complement(3372154..3373011) Escherichia coli O157:H7 str. EC4115 6968799 YP_002271905.1 CDS murQ NC_011353.1 3373175 3374071 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 3373175..3374071 Escherichia coli O157:H7 str. EC4115 6967947 YP_002271906.1 CDS murP NC_011353.1 3374075 3375499 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 3374075..3375499 Escherichia coli O157:H7 str. EC4115 6968037 YP_002271907.1 CDS ECH74115_3660 NC_011353.1 3375504 3376808 D identified by match to protein family HMM PF00144; hypothetical protein 3375504..3376808 Escherichia coli O157:H7 str. EC4115 6967564 YP_002271908.1 CDS ECH74115_3661 NC_011353.1 3376866 3377765 R identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413; dyp-type peroxidase family protein complement(3376866..3377765) Escherichia coli O157:H7 str. EC4115 6966761 YP_002271909.1 CDS ECH74115_3662 NC_011353.1 3377861 3378436 R identified by match to protein family HMM PF06572; hypothetical protein complement(3377861..3378436) Escherichia coli O157:H7 str. EC4115 6971186 YP_002271910.1 CDS ECH74115_3663 NC_011353.1 3378497 3378844 R inner membrane protein YfeZ complement(3378497..3378844) Escherichia coli O157:H7 str. EC4115 6971253 YP_002271911.1 CDS ECH74115_3664 NC_011353.1 3378933 3379358 R identified by match to protein family HMM PF00583; acetyltransferase complement(3378933..3379358) Escherichia coli O157:H7 str. EC4115 6972114 YP_002271912.1 CDS amiA NC_011353.1 3379572 3380441 D identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-l-alanine amidase I 3379572..3380441 Escherichia coli O157:H7 str. EC4115 6967987 YP_002271913.1 CDS hemF NC_011353.1 3380445 3381344 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 3380445..3381344 Escherichia coli O157:H7 str. EC4115 6968811 YP_002271914.1 CDS ECH74115_3667 NC_011353.1 3381350 3382402 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(3381350..3382402) Escherichia coli O157:H7 str. EC4115 6966742 YP_002271915.1 CDS ECH74115_3668 NC_011353.1 3382448 3382948 R identified by match to protein family HMM PF00936; ethanolamine utilization protein EutK complement(3382448..3382948) Escherichia coli O157:H7 str. EC4115 6967542 YP_002271916.1 CDS ECH74115_3669 NC_011353.1 3382961 3383620 R identified by match to protein family HMM PF00936; ethanolamine utilization protein EutL complement(3382961..3383620) Escherichia coli O157:H7 str. EC4115 6967615 YP_002271917.1 CDS eutC NC_011353.1 3383630 3384517 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(3383630..3384517) Escherichia coli O157:H7 str. EC4115 6971468 YP_002271918.1 CDS eutB NC_011353.1 3384538 3385899 R identified by match to protein family HMM PF06751; ethanolamine ammonia-lyase, large subunit complement(3384538..3385899) Escherichia coli O157:H7 str. EC4115 6971759 YP_002271919.1 CDS eutA NC_011353.1 3385911 3387314 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(3385911..3387314) Escherichia coli O157:H7 str. EC4115 6969864 YP_002271920.1 CDS eutH NC_011353.1 3387311 3388537 R identified by match to protein family HMM PF04346; ethanolamine utilization protein EutH complement(3387311..3388537) Escherichia coli O157:H7 str. EC4115 6971201 YP_002271921.1 CDS eutG NC_011353.1 3388637 3389824 R identified by match to protein family HMM PF00465; ethanolamine utilization protein EutG complement(3388637..3389824) Escherichia coli O157:H7 str. EC4115 6971371 YP_002271922.1 CDS eutJ NC_011353.1 3389814 3390650 R identified by match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ complement(3389814..3390650) Escherichia coli O157:H7 str. EC4115 6966764 YP_002271923.1 CDS eutE NC_011353.1 3390661 3392064 R identified by match to protein family HMM PF00171; ethanolamine utilization protein EutE complement(3390661..3392064) Escherichia coli O157:H7 str. EC4115 6968949 YP_002271924.1 CDS eutN NC_011353.1 3392076 3392363 R identified by match to protein family HMM PF03319; ethanolamine utilization protein complement(3392076..3392363) Escherichia coli O157:H7 str. EC4115 6970536 YP_002271925.1 CDS eutM NC_011353.1 3392470 3392763 R identified by match to protein family HMM PF00936; ethanolamine utilization protein EutM complement(3392470..3392763) Escherichia coli O157:H7 str. EC4115 6969904 YP_002271926.1 CDS eutD NC_011353.1 3392802 3393818 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(3392802..3393818) Escherichia coli O157:H7 str. EC4115 6970108 YP_002271927.1 CDS ECH74115_3680 NC_011353.1 3393815 3394546 R identified by match to protein family HMM PF01923; ethanolamine utilization cobalamin adenosyltransferase complement(3393815..3394546) Escherichia coli O157:H7 str. EC4115 6971931 YP_002271928.1 CDS eutQ NC_011353.1 3394543 3395244 R identified by match to protein family HMM PF05899; match to protein family HMM PF06249; ethanolamine utilization protein EutQ complement(3394543..3395244) Escherichia coli O157:H7 str. EC4115 6970957 YP_002271929.1 CDS eutP NC_011353.1 3395219 3395698 R identified by match to protein family HMM TIGR02528; ethanolamine utilization protein, EutP complement(3395219..3395698) Escherichia coli O157:H7 str. EC4115 6967835 YP_002271930.1 CDS ECH74115_3683 NC_011353.1 3395711 3396046 R identified by match to protein family HMM PF00936; ethanolamine utilization protein EutS complement(3395711..3396046) Escherichia coli O157:H7 str. EC4115 6971597 YP_002271931.1 CDS maeB NC_011353.1 3396339 3398618 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(3396339..3398618) Escherichia coli O157:H7 str. EC4115 6968427 YP_002271932.1 CDS tal1 NC_011353.1 3398907 3399857 D identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase A 3398907..3399857 Escherichia coli O157:H7 str. EC4115 6969083 YP_002271933.1 CDS tktB NC_011353.1 3399877 3401880 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3399877..3401880 Escherichia coli O157:H7 str. EC4115 6970304 YP_002271934.1 CDS ECH74115_3687 NC_011353.1 3401975 3403018 R identified by match to protein family HMM PF06674; hypothetical protein complement(3401975..3403018) Escherichia coli O157:H7 str. EC4115 6969680 YP_002271935.1 CDS ECH74115_3688 NC_011353.1 3403144 3403719 R identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052; NUDIX family hydrolase complement(3403144..3403719) Escherichia coli O157:H7 str. EC4115 6971554 YP_002271936.1 CDS aegA NC_011353.1 3403787 3405766 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3403787..3405766) Escherichia coli O157:H7 str. EC4115 6970900 YP_002271937.1 CDS narQ NC_011353.1 3405972 3407672 D identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarQ 3405972..3407672 Escherichia coli O157:H7 str. EC4115 6967799 YP_002271938.1 CDS acrD NC_011353.1 3407836 3410949 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; aminoglycoside/multidrug efflux system 3407836..3410949 Escherichia coli O157:H7 str. EC4115 6967154 YP_002271939.1 CDS ECH74115_3692 NC_011353.1 3411488 3411844 D identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 3411488..3411844 Escherichia coli O157:H7 str. EC4115 6969048 YP_002271940.1 CDS dapE NC_011353.1 3411848 3412975 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 3411848..3412975 Escherichia coli O157:H7 str. EC4115 6967106 YP_002271941.1 CDS ECH74115_3694 NC_011353.1 3413003 3413203 D hypothetical protein 3413003..3413203 Escherichia coli O157:H7 str. EC4115 6967393 YP_002271942.1 CDS ECH74115_3695 NC_011353.1 3413284 3413982 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH complement(3413284..3413982) Escherichia coli O157:H7 str. EC4115 6969462 YP_002271943.1 CDS ECH74115_3696 NC_011353.1 3414056 3416071 R identified by match to protein family HMM PF00583; match to protein family HMM PF05127; hypothetical protein complement(3414056..3416071) Escherichia coli O157:H7 str. EC4115 6970269 YP_002271944.1 CDS ECH74115_3697 NC_011353.1 3416086 3416949 R identified by match to protein family HMM PF04228; hypothetical protein complement(3416086..3416949) Escherichia coli O157:H7 str. EC4115 6968542 YP_002271945.1 CDS purC NC_011353.1 3417117 3417830 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase complement(3417117..3417830) Escherichia coli O157:H7 str. EC4115 6969325 YP_002271946.1 CDS ECH74115_3699 NC_011353.1 3418043 3419077 R identified by match to protein family HMM PF06804; lipoprotein complement(3418043..3419077) Escherichia coli O157:H7 str. EC4115 6966895 YP_002271947.1 CDS dapA NC_011353.1 3419094 3419972 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(3419094..3419972) Escherichia coli O157:H7 str. EC4115 6967689 YP_002271948.1 CDS gcvR NC_011353.1 3420118 3420690 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 3420118..3420690 Escherichia coli O157:H7 str. EC4115 6967591 YP_002271949.1 CDS bcp NC_011353.1 3420690 3421160 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 3420690..3421160 Escherichia coli O157:H7 str. EC4115 6970838 YP_002271950.1 CDS hyfA NC_011353.1 3421413 3422030 D identified by match to protein family HMM PF00037; hydrogenase-4 subunit A 3421413..3422030 Escherichia coli O157:H7 str. EC4115 6967694 YP_002271951.1 CDS hyfB NC_011353.1 3422030 3424048 D identified by match to protein family HMM PF00361; hydrogenase 4 subunit B 3422030..3424048 Escherichia coli O157:H7 str. EC4115 6968338 YP_002271952.1 CDS hyfC NC_011353.1 3424059 3425006 D identified by match to protein family HMM PF00146; hydrogenase-4 subunit C 3424059..3425006 Escherichia coli O157:H7 str. EC4115 6969281 YP_002271953.1 CDS ECH74115_3706 NC_011353.1 3425023 3426462 D identified by match to protein family HMM PF00361; hydrogenase 4 subunit D 3425023..3426462 Escherichia coli O157:H7 str. EC4115 6968644 YP_002271954.1 CDS hyfE NC_011353.1 3426474 3427124 D interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 3426474..3427124 Escherichia coli O157:H7 str. EC4115 6967695 YP_002271955.1 CDS ECH74115_3708 NC_011353.1 3427144 3428709 D identified by match to protein family HMM PF00361; hydrogenase 4 subunit F 3427144..3428709 Escherichia coli O157:H7 str. EC4115 6966919 YP_002271956.1 CDS ECH74115_3709 NC_011353.1 3428699 3430414 D identified by match to protein family HMM PF00329; match to protein family HMM PF00346; hydrogenase-4, G subunit 3428699..3430414 Escherichia coli O157:H7 str. EC4115 6971771 YP_002271957.1 CDS ECH74115_3710 NC_011353.1 3430424 3430969 D probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 3430424..3430969 Escherichia coli O157:H7 str. EC4115 6971152 YP_002271958.1 CDS ECH74115_3711 NC_011353.1 3430966 3431724 D identified by match to protein family HMM PF01058; hydrogenase-4, I subunit 3430966..3431724 Escherichia coli O157:H7 str. EC4115 6970156 YP_002271959.1 CDS ECH74115_3712 NC_011353.1 3431717 3432130 D identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein HycH 3431717..3432130 Escherichia coli O157:H7 str. EC4115 6969517 YP_002271960.1 CDS ECH74115_3713 NC_011353.1 3432160 3434172 D identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; formate hydrogenlyase transcriptional activator 3432160..3434172 Escherichia coli O157:H7 str. EC4115 6970178 YP_002271961.1 CDS focB NC_011353.1 3434194 3435042 D inner membrane protein presumed to act as a formate transporter; member of the hyf operon; formate transporter 3434194..3435042 Escherichia coli O157:H7 str. EC4115 6967646 YP_002271962.1 CDS ECH74115_3715 NC_011353.1 3435080 3436141 R identified by match to protein family HMM PF01594; permease, PerM family complement(3435080..3436141) Escherichia coli O157:H7 str. EC4115 6968815 YP_002271963.1 CDS ECH74115_3716 NC_011353.1 3436354 3437817 D identified by match to protein family HMM PF01435; M48 family peptidase 3436354..3437817 Escherichia coli O157:H7 str. EC4115 6966624 YP_002271964.1 CDS arsC1 NC_011353.1 3437838 3438197 D identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 3437838..3438197 Escherichia coli O157:H7 str. EC4115 6970693 YP_002271965.1 CDS hda NC_011353.1 3438335 3439081 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(3438335..3439081) Escherichia coli O157:H7 str. EC4115 6968561 YP_002271966.1 CDS uraA NC_011353.1 3439131 3440420 R identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil transporter complement(3439131..3440420) Escherichia coli O157:H7 str. EC4115 6972008 YP_002271967.1 CDS upp NC_011353.1 3440506 3441132 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(3440506..3441132) Escherichia coli O157:H7 str. EC4115 6969791 YP_002271968.1 CDS purM NC_011353.1 3441457 3442494 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 3441457..3442494 Escherichia coli O157:H7 str. EC4115 6967492 YP_002271969.1 CDS purN NC_011353.1 3442494 3443132 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3442494..3443132 Escherichia coli O157:H7 str. EC4115 6966855 YP_002271970.1 CDS ppk NC_011353.1 3443303 3445369 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3443303..3445369 Escherichia coli O157:H7 str. EC4115 6966644 YP_002271971.1 CDS ppx NC_011353.1 3445374 3446915 D identified by match to protein family HMM PF02541; exopolyphosphatase 3445374..3446915 Escherichia coli O157:H7 str. EC4115 6970225 YP_002271972.1 CDS ECH74115_3726 NC_011353.1 3446954 3449197 R identified by match to protein family HMM PF00563; match to protein family HMM PF05231; cytochrome C-type biogenesis protein complement(3446954..3449197) Escherichia coli O157:H7 str. EC4115 6969418 YP_002271973.1 CDS ECH74115_3727 NC_011353.1 3449379 3449531 R hypothetical protein complement(3449379..3449531) Escherichia coli O157:H7 str. EC4115 6971968 YP_002271974.1 CDS ECH74115_3728 NC_011353.1 3449549 3449740 D hypothetical protein 3449549..3449740 Escherichia coli O157:H7 str. EC4115 6971157 YP_002271975.1 CDS ECH74115_3729 NC_011353.1 3450054 3450569 D identified by match to protein family HMM PF05433; surface antigen family protein 3450054..3450569 Escherichia coli O157:H7 str. EC4115 6967829 YP_002271976.1 CDS ECH74115_3730 NC_011353.1 3450585 3451124 D hypothetical protein 3450585..3451124 Escherichia coli O157:H7 str. EC4115 6967046 YP_002271977.1 CDS guaA NC_011353.1 3451217 3452794 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(3451217..3452794) Escherichia coli O157:H7 str. EC4115 6966589 YP_002271978.1 CDS guaB NC_011353.1 3452863 3454374 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(3452863..3454374) Escherichia coli O157:H7 str. EC4115 6968597 YP_002271979.1 CDS xseA NC_011353.1 3454491 3455861 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3454491..3455861 Escherichia coli O157:H7 str. EC4115 6968275 YP_002271980.1 CDS ECH74115_3733 NC_011353.1 3455858 3456073 R identified by match to protein family HMM PF07191; hypothetical protein complement(3455858..3456073) Escherichia coli O157:H7 str. EC4115 6971795 YP_002271981.1 CDS engA NC_011353.1 3456142 3457614 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(3456142..3457614) Escherichia coli O157:H7 str. EC4115 6967089 YP_002271982.1 CDS ECH74115_3736 NC_011353.1 3457732 3458910 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(3457732..3458910) Escherichia coli O157:H7 str. EC4115 6970827 YP_002271983.1 CDS ECH74115_3737 NC_011353.1 3458921 3459541 R hypothetical protein complement(3458921..3459541) Escherichia coli O157:H7 str. EC4115 6969639 YP_002271984.1 CDS hisS NC_011353.1 3459559 3460833 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(3459559..3460833) Escherichia coli O157:H7 str. EC4115 6968665 YP_002271985.1 CDS ispG NC_011353.1 3460944 3462062 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(3460944..3462062) Escherichia coli O157:H7 str. EC4115 6972305 YP_002271986.1 CDS ECH74115_3741 NC_011353.1 3462089 3463102 R identified by match to protein family HMM PF01381; cytoskeletal protein RodZ complement(3462089..3463102) Escherichia coli O157:H7 str. EC4115 6968464 YP_002271987.1 CDS ECH74115_3742 NC_011353.1 3463387 3464541 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(3463387..3464541) Escherichia coli O157:H7 str. EC4115 6967193 YP_002271988.1 CDS ndk NC_011353.1 3464691 3465122 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(3464691..3465122) Escherichia coli O157:H7 str. EC4115 6971979 YP_002271989.1 CDS ECH74115_3744 NC_011353.1 3465263 3466117 R identified by match to protein family HMM PF00037; polyferredoxin complement(3465263..3466117) Escherichia coli O157:H7 str. EC4115 6970959 YP_002271990.1 CDS ECH74115_3745 NC_011353.1 3466117 3466938 R anaerobic dimethyl sulfoxide reductase subunit C complement(3466117..3466938) Escherichia coli O157:H7 str. EC4115 6969453 YP_002271991.1 CDS dmsB NC_011353.1 3466931 3467560 R identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951; dimethylsulfoxide reductase subunit B complement(3466931..3467560) Escherichia coli O157:H7 str. EC4115 6968034 YP_002271992.1 CDS ECH74115_3747 NC_011353.1 3467557 3469938 R identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A complement(3467557..3469938) Escherichia coli O157:H7 str. EC4115 6968810 YP_002271993.1 CDS pbpC NC_011353.1 3470102 3472414 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(3470102..3472414) Escherichia coli O157:H7 str. EC4115 6966771 YP_002271994.1 CDS ECH74115_3749 NC_011353.1 3472415 3477376 R identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin domain-containing protein complement(3472415..3477376) Escherichia coli O157:H7 str. EC4115 6967571 YP_002271995.1 CDS sseA NC_011353.1 3477583 3478428 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 3477583..3478428 Escherichia coli O157:H7 str. EC4115 6971871 YP_002271996.1 CDS sseB NC_011353.1 3478928 3479704 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(3478928..3479704) Escherichia coli O157:H7 str. EC4115 6972311 YP_002271997.1 CDS pepB NC_011353.1 3479847 3481130 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(3479847..3481130) Escherichia coli O157:H7 str. EC4115 6968488 YP_002271998.1 CDS iscX NC_011353.1 3481308 3481508 R identified by match to protein family HMM PF04384; match to protein family HMM TIGR03412; hypothetical protein complement(3481308..3481508) Escherichia coli O157:H7 str. EC4115 6967087 YP_002271999.1 CDS fdx NC_011353.1 3481520 3481855 R identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007; ferredoxin, 2Fe-2S type, ISC system complement(3481520..3481855) Escherichia coli O157:H7 str. EC4115 6969501 YP_002272000.1 CDS hscA NC_011353.1 3481857 3483707 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(3481857..3483707) Escherichia coli O157:H7 str. EC4115 6970168 YP_002272001.1 CDS hscB NC_011353.1 3483724 3484239 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(3483724..3484239) Escherichia coli O157:H7 str. EC4115 6968622 YP_002272002.1 CDS ECH74115_3759 NC_011353.1 3484247 3484363 R identified by glimmer; hypothetical protein complement(3484247..3484363) Escherichia coli O157:H7 str. EC4115 6966986 YP_002272003.1 CDS iscA NC_011353.1 3484335 3484664 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(3484335..3484664) Escherichia coli O157:H7 str. EC4115 6970992 YP_002272004.1 CDS iscU NC_011353.1 3484675 3485061 R identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999; scaffold protein complement(3484675..3485061) Escherichia coli O157:H7 str. EC4115 6971831 YP_002272005.1 CDS iscS NC_011353.1 3485089 3486303 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(3485089..3486303) Escherichia coli O157:H7 str. EC4115 6969440 YP_002272006.1 CDS iscR NC_011353.1 3486415 3486903 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(3486415..3486903) Escherichia coli O157:H7 str. EC4115 6969470 YP_002272007.1 CDS ECH74115_3764 NC_011353.1 3487204 3487941 R identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; TrmH family RNA methyltransferase complement(3487204..3487941) Escherichia coli O157:H7 str. EC4115 6970256 YP_002272008.1 CDS suhB NC_011353.1 3488060 3488863 D identified by match to protein family HMM PF00459; inositol monophosphatase 3488060..3488863 Escherichia coli O157:H7 str. EC4115 6968575 YP_002272009.1 CDS ECH74115_3766 NC_011353.1 3489008 3489862 D hypothetical protein 3489008..3489862 Escherichia coli O157:H7 str. EC4115 6966793 YP_002272010.1 CDS csiE NC_011353.1 3490053 3491333 D identified by match to protein family HMM PF00874; stationary phase inducible protein CsiE 3490053..3491333 Escherichia coli O157:H7 str. EC4115 6969991 YP_002272011.1 CDS hcaT NC_011353.1 3491325 3492464 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(3491325..3492464) Escherichia coli O157:H7 str. EC4115 6971295 YP_002272012.1 CDS hcaR NC_011353.1 3492624 3493514 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR complement(3492624..3493514) Escherichia coli O157:H7 str. EC4115 6970236 YP_002272013.1 CDS hcaF NC_011353.1 3495008 3495526 D identified by match to protein family HMM PF00866; 3-phenylpropionate dioxygenase subunit beta 3495008..3495526 Escherichia coli O157:H7 str. EC4115 6966724 YP_002272014.1 CDS hcaC NC_011353.1 3495526 3495846 D identified by match to protein family HMM PF00355; 3-phenylpropionate dioxygenase ferredoxin subunit 3495526..3495846 Escherichia coli O157:H7 str. EC4115 6971282 YP_002272015.1 CDS hcaB NC_011353.1 3495843 3496655 D Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 3495843..3496655 Escherichia coli O157:H7 str. EC4115 6968101 YP_002272016.1 CDS hcaD NC_011353.1 3496665 3497867 D identified by match to protein family HMM PF00070; match to protein family HMM PF07992; phenylpropionate dioxygenase ferredoxin reductase subunit 3496665..3497867 Escherichia coli O157:H7 str. EC4115 6968709 YP_002272017.1 CDS ECH74115_3775 NC_011353.1 3497964 3498386 D identified by match to protein family HMM PF07681; inner membrane protein YphA 3497964..3498386 Escherichia coli O157:H7 str. EC4115 6970321 YP_002272018.1 CDS ECH74115_3776 NC_011353.1 3498434 3499306 R identified by match to protein family HMM PF01263; aldose 1-epimerase family protein complement(3498434..3499306) Escherichia coli O157:H7 str. EC4115 6966651 YP_002272019.1 CDS ECH74115_3779 NC_011353.1 3500445 3501443 R identified by match to protein family HMM PF02653; sugar ABC transporter permease complement(3500445..3501443) Escherichia coli O157:H7 str. EC4115 6971748 YP_002272020.1 CDS ECH74115_3780 NC_011353.1 3501468 3502979 R identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein complement(3501468..3502979) Escherichia coli O157:H7 str. EC4115 6971122 YP_002272021.1 CDS ECH74115_3781 NC_011353.1 3503002 3503985 R identified by match to protein family HMM PF00532; sugar ABC transporter substrate-binding protein complement(3503002..3503985) Escherichia coli O157:H7 str. EC4115 6967636 YP_002272022.1 CDS ECH74115_3782 NC_011353.1 3504082 3507456 R identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein complement(3504082..3507456) Escherichia coli O157:H7 str. EC4115 6967023 YP_002272023.1 CDS ECH74115_3783 NC_011353.1 3507481 3508674 D identified by match to protein family HMM PF00480; ROK family protein 3507481..3508674 Escherichia coli O157:H7 str. EC4115 6968087 YP_002272024.1 CDS glyA NC_011353.1 3508737 3509990 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(3508737..3509990) Escherichia coli O157:H7 str. EC4115 6968615 YP_002272025.1 CDS ECH74115_3785 NC_011353.1 3510142 3510270 D hypothetical protein 3510142..3510270 Escherichia coli O157:H7 str. EC4115 6969673 YP_002272026.1 CDS hmp NC_011353.1 3510318 3511508 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 3510318..3511508 Escherichia coli O157:H7 str. EC4115 6969416 YP_002272027.1 CDS glnB NC_011353.1 3511553 3511891 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(3511553..3511891) Escherichia coli O157:H7 str. EC4115 6967285 YP_002272028.1 CDS ECH74115_3788 NC_011353.1 3511952 3513286 R identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728; sigma-54 dependent response regulator complement(3511952..3513286) Escherichia coli O157:H7 str. EC4115 6966578 YP_002272029.1 CDS ECH74115_3789 NC_011353.1 3513276 3513911 R hypothetical protein complement(3513276..3513911) Escherichia coli O157:H7 str. EC4115 6968899 YP_002272030.1 CDS ECH74115_3790 NC_011353.1 3514154 3515581 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase complement(3514154..3515581) Escherichia coli O157:H7 str. EC4115 6967720 YP_002272031.1 CDS purL NC_011353.1 3516157 3520044 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(3516157..3520044) Escherichia coli O157:H7 str. EC4115 6972286 YP_002272032.1 CDS ECH74115_3794 NC_011353.1 3520301 3521857 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 3520301..3521857 Escherichia coli O157:H7 str. EC4115 6969354 YP_002272033.1 CDS tadA NC_011353.1 3521854 3522357 R identified by match to protein family HMM PF00383; tRNA-specific adenosine deaminase complement(3521854..3522357) Escherichia coli O157:H7 str. EC4115 6970199 YP_002272034.1 CDS yhfB NC_011353.1 3522415 3523050 R identified by match to protein family HMM TIGR01545; hypothetical protein complement(3522415..3523050) Escherichia coli O157:H7 str. EC4115 6971358 YP_002272035.1 CDS ECH74115_3796 NC_011353.1 3523259 3524107 D identified by match to protein family HMM PF01380; match to protein family HMM PF01418; DNA-binding transcriptional regulator 3523259..3524107 Escherichia coli O157:H7 str. EC4115 6968502 YP_002272036.1 CDS ECH74115_3797 NC_011353.1 3524139 3524423 D 4Fe-4S binding protein 3524139..3524423 Escherichia coli O157:H7 str. EC4115 6969629 YP_002272037.1 CDS ECH74115_3798 NC_011353.1 3524890 3525012 D identified by glimmer; hypothetical protein 3524890..3525012 Escherichia coli O157:H7 str. EC4115 6970419 YP_002272038.1 CDS acpS NC_011353.1 3525119 3525499 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(3525119..3525499) Escherichia coli O157:H7 str. EC4115 6968015 YP_002272039.1 CDS pdxJ NC_011353.1 3525499 3526230 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(3525499..3526230) Escherichia coli O157:H7 str. EC4115 6968796 YP_002272040.1 CDS recO NC_011353.1 3526242 3526970 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(3526242..3526970) Escherichia coli O157:H7 str. EC4115 6967117 YP_002272041.1 CDS era NC_011353.1 3526982 3527887 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(3526982..3527887) Escherichia coli O157:H7 str. EC4115 6967912 YP_002272042.1 CDS rnc NC_011353.1 3527884 3528564 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(3527884..3528564) Escherichia coli O157:H7 str. EC4115 6971223 YP_002272043.1 CDS lepB NC_011353.1 3528837 3529811 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(3528837..3529811) Escherichia coli O157:H7 str. EC4115 6972013 YP_002272044.1 CDS lepA NC_011353.1 3529827 3531626 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(3529827..3531626) Escherichia coli O157:H7 str. EC4115 6971718 YP_002272045.1 CDS rseC NC_011353.1 3531824 3532303 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(3531824..3532303) Escherichia coli O157:H7 str. EC4115 6969724 YP_002272046.1 CDS rseB NC_011353.1 3532300 3533256 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(3532300..3533256) Escherichia coli O157:H7 str. EC4115 6967962 YP_002272047.1 CDS rseA NC_011353.1 3533256 3533894 R identified by match to protein family HMM PF03872; match to protein family HMM PF03873; anti-RNA polymerase sigma factor SigE complement(3533256..3533894) Escherichia coli O157:H7 str. EC4115 6967590 YP_002272048.1 CDS rpoE NC_011353.1 3533927 3534502 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(3533927..3534502) Escherichia coli O157:H7 str. EC4115 6966769 YP_002272049.1 CDS nadB NC_011353.1 3534940 3536532 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 3534940..3536532 Escherichia coli O157:H7 str. EC4115 6972035 YP_002272050.1 CDS ECH74115_3811 NC_011353.1 3536517 3537254 R identified by match to protein family HMM PF05175; methyltransferase complement(3536517..3537254) Escherichia coli O157:H7 str. EC4115 6970795 YP_002272051.1 CDS srmB NC_011353.1 3537386 3538720 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3537386..3538720 Escherichia coli O157:H7 str. EC4115 6971237 YP_002272052.1 CDS ECH74115_3814 NC_011353.1 3538753 3539679 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(3538753..3539679) Escherichia coli O157:H7 str. EC4115 6968778 YP_002272053.1 CDS ECH74115_3815 NC_011353.1 3539737 3540324 D identified by match to protein family HMM PF01810; neutral amino-acid efflux protein 3539737..3540324 Escherichia coli O157:H7 str. EC4115 6968004 YP_002272054.1 CDS grcA NC_011353.1 3540380 3540763 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(3540380..3540763) Escherichia coli O157:H7 str. EC4115 6967473 YP_002272055.1 CDS ung NC_011353.1 3541068 3541757 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3541068..3541757 Escherichia coli O157:H7 str. EC4115 6967043 YP_002272056.1 CDS ECH74115_3818 NC_011353.1 3541805 3542842 R identified by match to protein family HMM PF00588; match to protein family HMM PF08032; methyltransferase complement(3541805..3542842) Escherichia coli O157:H7 str. EC4115 6969365 YP_002272057.1 CDS ECH74115_3819 NC_011353.1 3543049 3543468 D identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2 3543049..3543468 Escherichia coli O157:H7 str. EC4115 6968251 YP_002272058.1 CDS ECH74115_3820 NC_011353.1 3543537 3544235 D identified by match to protein family HMM PF03942; DTW domain-containing protein 3543537..3544235 Escherichia coli O157:H7 str. EC4115 6967426 YP_002272059.1 CDS ECH74115_3821 NC_011353.1 3544267 3546927 D identified by match to protein family HMM PF00583; match to protein family HMM PF02629; GNAT family acetyltransferase 3544267..3546927 Escherichia coli O157:H7 str. EC4115 6972055 YP_002272060.1 CDS pssA NC_011353.1 3547041 3548396 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3547041..3548396 Escherichia coli O157:H7 str. EC4115 6971777 YP_002272061.1 CDS ECH74115_3824 NC_011353.1 3548421 3548765 D hypothetical protein 3548421..3548765 Escherichia coli O157:H7 str. EC4115 6970734 YP_002272062.1 CDS kgtP NC_011353.1 3548762 3550141 R identified by match to protein family HMM PF00083; alpha-ketoglutarate transporter complement(3548762..3550141) Escherichia coli O157:H7 str. EC4115 6968743 YP_002272063.1 CDS ECH74115_3825 NC_011353.1 3550021 3550302 D identified by glimmer; hypothetical protein 3550021..3550302 Escherichia coli O157:H7 str. EC4115 6970063 YP_002272064.1 CDS ECH74115_3832 NC_011353.1 3555653 3555787 D hypothetical protein 3555653..3555787 Escherichia coli O157:H7 str. EC4115 6972282 YP_002272065.1 CDS clpB NC_011353.1 3555828 3558401 R identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346; protein disaggregation chaperone complement(3555828..3558401) Escherichia coli O157:H7 str. EC4115 6969982 YP_002272066.1 CDS ECH74115_3834 NC_011353.1 3558531 3559262 R identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein complement(3558531..3559262) Escherichia coli O157:H7 str. EC4115 6968784 YP_002272067.1 CDS rluD NC_011353.1 3559259 3560239 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(3559259..3560239) Escherichia coli O157:H7 str. EC4115 6967818 YP_002272068.1 CDS ECH74115_3836 NC_011353.1 3560374 3561111 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3560374..3561111 Escherichia coli O157:H7 str. EC4115 6967555 YP_002272069.1 CDS ECH74115_3837 NC_011353.1 3561382 3561723 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3561382..3561723 Escherichia coli O157:H7 str. EC4115 6966562 YP_002272070.1 CDS pheA NC_011353.1 3561973 3563133 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3561973..3563133 Escherichia coli O157:H7 str. EC4115 6970980 YP_002272071.1 CDS tyrA NC_011353.1 3563176 3564297 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(3563176..3564297) Escherichia coli O157:H7 str. EC4115 6970161 YP_002272072.1 CDS aroF NC_011353.1 3564308 3565378 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3564308..3565378) Escherichia coli O157:H7 str. EC4115 6970104 YP_002272073.1 CDS ECH74115_3841 NC_011353.1 3565588 3565953 D hypothetical protein 3565588..3565953 Escherichia coli O157:H7 str. EC4115 6969271 YP_002272074.1 CDS ECH74115_3842 NC_011353.1 3566103 3566621 D hypothetical protein 3566103..3566621 Escherichia coli O157:H7 str. EC4115 6967899 YP_002272075.1 CDS ECH74115_3843 NC_011353.1 3566614 3567837 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein 3566614..3567837 Escherichia coli O157:H7 str. EC4115 6968842 YP_002272076.1 CDS ECH74115_3844 NC_011353.1 3567853 3568335 D identified by match to protein family HMM PF00691; outer membrane lipoprotein 3567853..3568335 Escherichia coli O157:H7 str. EC4115 6968378 YP_002272077.1 CDS rplS NC_011353.1 3568412 3568759 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(3568412..3568759) Escherichia coli O157:H7 str. EC4115 6970443 YP_002272078.1 CDS trmD NC_011353.1 3568801 3569568 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(3568801..3569568) Escherichia coli O157:H7 str. EC4115 6970031 YP_002272079.1 CDS rimM NC_011353.1 3569599 3570150 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(3569599..3570150) Escherichia coli O157:H7 str. EC4115 6972093 YP_002272080.1 CDS rpsP NC_011353.1 3570166 3570414 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(3570166..3570414) Escherichia coli O157:H7 str. EC4115 6967402 YP_002272081.1 CDS ffh NC_011353.1 3570551 3571912 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(3570551..3571912) Escherichia coli O157:H7 str. EC4115 6966612 YP_002272082.1 CDS ECH74115_3850 NC_011353.1 3572004 3572870 D identified by match to protein family HMM PF01578; cytochrome C assembly protein 3572004..3572870 Escherichia coli O157:H7 str. EC4115 6969014 YP_002272083.1 CDS grpE NC_011353.1 3574232 3574825 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(3574232..3574825) Escherichia coli O157:H7 str. EC4115 6967345 YP_002272084.1 CDS ppnK NC_011353.1 3574948 3575826 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3574948..3575826 Escherichia coli O157:H7 str. EC4115 6969725 YP_002272085.1 CDS recN NC_011353.1 3575912 3577573 D identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; recombination and repair protein 3575912..3577573 Escherichia coli O157:H7 str. EC4115 6970748 YP_002272086.1 CDS ECH74115_3857 NC_011353.1 3577722 3578063 D identified by match to protein family HMM PF04355; hypothetical protein 3577722..3578063 Escherichia coli O157:H7 str. EC4115 6968474 YP_002272087.1 CDS ECH74115_3858 NC_011353.1 3578125 3578415 R identified by match to protein family HMM PF03658; hypothetical protein complement(3578125..3578415) Escherichia coli O157:H7 str. EC4115 6967219 YP_002272088.1 CDS ECH74115_3859 NC_011353.1 3578405 3578881 R identified by match to protein family HMM PF03364; hypothetical protein complement(3578405..3578881) Escherichia coli O157:H7 str. EC4115 6967847 YP_002272089.1 CDS smpB NC_011353.1 3579013 3579495 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3579013..3579495 Escherichia coli O157:H7 str. EC4115 6967470 YP_002272090.1 CDS ECH74115_3864 NC_011353.1 3580341 3580589 D identified by match to protein family HMM PF06183; hypothetical protein 3580341..3580589 Escherichia coli O157:H7 str. EC4115 6972438 YP_002272091.1 CDS ECH74115_3863 NC_011353.1 3580586 3580732 R hypothetical protein complement(3580586..3580732) Escherichia coli O157:H7 str. EC4115 6967898 YP_002272092.1 CDS ECH74115_3865 NC_011353.1 3580752 3580913 D hypothetical protein 3580752..3580913 Escherichia coli O157:H7 str. EC4115 6968426 YP_002272093.1 CDS ECH74115_3866 NC_011353.1 3581091 3581507 R identified by match to protein family HMM PF03278; EspM3 protein complement(3581091..3581507) Escherichia coli O157:H7 str. EC4115 6967140 YP_002272094.1 CDS ECH74115_3867 NC_011353.1 3581791 3581958 R identified by glimmer; hypothetical protein complement(3581791..3581958) Escherichia coli O157:H7 str. EC4115 6971691 YP_002272095.1 CDS ECH74115_3868 NC_011353.1 3582450 3582563 R identified by glimmer; hypothetical protein complement(3582450..3582563) Escherichia coli O157:H7 str. EC4115 6970820 YP_002272096.1 CDS ECH74115_3869 NC_011353.1 3582593 3583651 D hypothetical protein 3582593..3583651 Escherichia coli O157:H7 str. EC4115 6970402 YP_002272097.1 CDS ECH74115_3870 NC_011353.1 3583781 3584188 R identified by match to protein family HMM PF06416; hypothetical protein complement(3583781..3584188) Escherichia coli O157:H7 str. EC4115 6969132 YP_002272098.1 CDS ECH74115_3871 NC_011353.1 3584364 3584633 R prophage tail fiber C-terminus family protein complement(3584364..3584633) Escherichia coli O157:H7 str. EC4115 6968417 YP_002272099.1 CDS ECH74115_3872 NC_011353.1 3584632 3584799 D hypothetical protein 3584632..3584799 Escherichia coli O157:H7 str. EC4115 6967602 YP_002272100.1 CDS ECH74115_3873 NC_011353.1 3584851 3585177 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 3584851..3585177 Escherichia coli O157:H7 str. EC4115 6967223 YP_002272101.1 CDS ECH74115_3874 NC_011353.1 3585174 3586064 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 3585174..3586064 Escherichia coli O157:H7 str. EC4115 6966596 YP_002272102.1 CDS ECH74115_3875 NC_011353.1 3586565 3586912 R identified by match to protein family HMM PF05717; IS66 family element, orf2 complement(3586565..3586912) Escherichia coli O157:H7 str. EC4115 6967215 YP_002272103.1 CDS ECH74115_3876 NC_011353.1 3587365 3587595 R lysozyme complement(3587365..3587595) Escherichia coli O157:H7 str. EC4115 6967841 YP_002272104.1 CDS ECH74115_3877 NC_011353.1 3587646 3587990 R identified by match to protein family HMM PF07041; hypothetical protein complement(3587646..3587990) Escherichia coli O157:H7 str. EC4115 6971353 YP_002272105.1 CDS ECH74115_3878 NC_011353.1 3587995 3588210 R identified by match to protein family HMM PF04971; hypothetical protein complement(3587995..3588210) Escherichia coli O157:H7 str. EC4115 6971954 YP_002272106.1 CDS ECH74115_3879 NC_011353.1 3588360 3590213 R identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein complement(3588360..3590213) Escherichia coli O157:H7 str. EC4115 6969705 YP_002272107.1 CDS ECH74115_3880 NC_011353.1 3590659 3590826 R hypothetical protein complement(3590659..3590826) Escherichia coli O157:H7 str. EC4115 6970373 YP_002272108.1 CDS ECH74115_3881 NC_011353.1 3590912 3591628 R hypothetical protein complement(3590912..3591628) Escherichia coli O157:H7 str. EC4115 6968102 YP_002272109.1 CDS ECH74115_3882 NC_011353.1 3591721 3591837 R identified by glimmer; hypothetical protein complement(3591721..3591837) Escherichia coli O157:H7 str. EC4115 6968725 YP_002272110.1 CDS ECH74115_3883 NC_011353.1 3591908 3592531 R identified by match to protein family HMM PF03589; antitermination protein Q complement(3591908..3592531) Escherichia coli O157:H7 str. EC4115 6969323 YP_002272111.1 CDS ECH74115_3884 NC_011353.1 3592528 3593193 R identified by match to protein family HMM PF00149; serine/threonine-protein phosphatase 1 complement(3592528..3593193) Escherichia coli O157:H7 str. EC4115 6966610 YP_002272112.1 CDS ECH74115_3885 NC_011353.1 3593190 3593801 R identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein complement(3593190..3593801) Escherichia coli O157:H7 str. EC4115 6968614 YP_002272113.1 CDS ECH74115_3886 NC_011353.1 3594672 3595427 D transposase InsI for insertion sequence element IS30B/C/D 3594672..3595427 Escherichia coli O157:H7 str. EC4115 6968788 YP_002272114.1 CDS ECH74115_3887 NC_011353.1 3595487 3595765 D hypothetical protein 3595487..3595765 Escherichia coli O157:H7 str. EC4115 6969400 YP_002272115.1 CDS ECH74115_3888 NC_011353.1 3595841 3597055 R hypothetical protein complement(3595841..3597055) Escherichia coli O157:H7 str. EC4115 6970425 YP_002272116.1 CDS ECH74115_3889 NC_011353.1 3597595 3598065 R hypothetical protein complement(3597595..3598065) Escherichia coli O157:H7 str. EC4115 6971153 YP_002272117.1 CDS ECH74115_3890 NC_011353.1 3598106 3598327 R hypothetical protein complement(3598106..3598327) Escherichia coli O157:H7 str. EC4115 6967093 YP_002272118.1 CDS ECH74115_3891 NC_011353.1 3598505 3600136 R DNA-binding protein complement(3598505..3600136) Escherichia coli O157:H7 str. EC4115 6967650 YP_002272119.1 CDS ECH74115_3892 NC_011353.1 3600133 3601446 R identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family protein complement(3600133..3601446) Escherichia coli O157:H7 str. EC4115 6967250 YP_002272120.1 CDS ECH74115_3894 NC_011353.1 3603282 3604133 R hypothetical protein complement(3603282..3604133) Escherichia coli O157:H7 str. EC4115 6966565 YP_002272121.1 CDS ECH74115_3895 NC_011353.1 3604560 3609275 R identified by glimmer; hypothetical protein complement(3604560..3609275) Escherichia coli O157:H7 str. EC4115 6967177 YP_002272122.1 CDS ECH74115_3896 NC_011353.1 3609211 3609330 R identified by glimmer; hypothetical protein complement(3609211..3609330) Escherichia coli O157:H7 str. EC4115 6971095 YP_002272123.1 CDS ECH74115_3901 NC_011353.1 3615408 3616385 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3615408..3616385 Escherichia coli O157:H7 str. EC4115 6968570 YP_002272124.1 CDS ECH74115_3902 NC_011353.1 3616405 3617673 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3616405..3617673 Escherichia coli O157:H7 str. EC4115 6967721 YP_002272125.1 CDS gabD NC_011353.1 3617696 3619144 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3617696..3619144 Escherichia coli O157:H7 str. EC4115 6971660 YP_002272126.1 CDS gabT2 NC_011353.1 3619158 3620438 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3619158..3620438 Escherichia coli O157:H7 str. EC4115 6970839 YP_002272127.1 CDS gabP NC_011353.1 3620676 3622076 D identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773; gamma-aminobutyrate transporter 3620676..3622076 Escherichia coli O157:H7 str. EC4115 6969779 YP_002272128.1 CDS csiR NC_011353.1 3622097 3622759 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3622097..3622759 Escherichia coli O157:H7 str. EC4115 6972160 YP_002272129.1 CDS ECH74115_3907 NC_011353.1 3622760 3623209 R identified by match to protein family HMM PF01476; match to protein family HMM PF04972; LysM domain/BON superfamily protein complement(3622760..3623209) Escherichia coli O157:H7 str. EC4115 6970561 YP_002272130.1 CDS ECH74115_3908 NC_011353.1 3623293 3623451 R identified by match to protein family HMM PF01679; hypothetical protein complement(3623293..3623451) Escherichia coli O157:H7 str. EC4115 6969994 YP_002272131.1 CDS ECH74115_3909 NC_011353.1 3623634 3623933 D identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 3623634..3623933 Escherichia coli O157:H7 str. EC4115 6968881 YP_002272132.1 CDS ECH74115_3910 NC_011353.1 3623943 3624461 D inner membrane protein 3623943..3624461 Escherichia coli O157:H7 str. EC4115 6968256 YP_002272133.1 CDS stpA NC_011353.1 3624514 3624918 R identified by match to protein family HMM PF00816; DNA binding protein complement(3624514..3624918) Escherichia coli O157:H7 str. EC4115 6971005 YP_002272134.1 CDS ECH74115_3912 NC_011353.1 3625586 3626035 D identified by match to protein family HMM PF06610; hypothetical protein 3625586..3626035 Escherichia coli O157:H7 str. EC4115 6971315 YP_002272135.1 CDS ECH74115_3913 NC_011353.1 3626072 3626416 R identified by match to protein family HMM PF09400; hypothetical protein complement(3626072..3626416) Escherichia coli O157:H7 str. EC4115 6970784 YP_002272136.1 CDS ECH74115_3914 NC_011353.1 3626568 3626897 D identified by match to protein family HMM PF05957; hypothetical protein 3626568..3626897 Escherichia coli O157:H7 str. EC4115 6970011 YP_002272137.1 CDS ECH74115_3915 NC_011353.1 3627047 3628381 R identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator complement(3627047..3628381) Escherichia coli O157:H7 str. EC4115 6970904 YP_002272138.1 CDS ECH74115_3916 NC_011353.1 3628469 3628900 D identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; carboxymuconolactone decarboxylase family protein 3628469..3628900 Escherichia coli O157:H7 str. EC4115 6971719 YP_002272139.1 CDS nrdH NC_011353.1 3629109 3629354 D identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194; glutaredoxin-like protein 3629109..3629354 Escherichia coli O157:H7 str. EC4115 6966960 YP_002272140.1 CDS nrdI NC_011353.1 3629351 3629761 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3629351..3629761 Escherichia coli O157:H7 str. EC4115 6967743 YP_002272141.1 CDS nrdE NC_011353.1 3629734 3631878 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3629734..3631878 Escherichia coli O157:H7 str. EC4115 6968571 YP_002272142.1 CDS nrdF NC_011353.1 3631888 3632847 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3631888..3632847 Escherichia coli O157:H7 str. EC4115 6969341 YP_002272143.1 CDS proV NC_011353.1 3633203 3634405 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3633203..3634405 Escherichia coli O157:H7 str. EC4115 6972082 YP_002272144.1 CDS proW NC_011353.1 3634398 3635462 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3634398..3635462 Escherichia coli O157:H7 str. EC4115 6969489 YP_002272145.1 CDS proX NC_011353.1 3635519 3636511 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3635519..3636511 Escherichia coli O157:H7 str. EC4115 6967264 YP_002272146.1 CDS ECH74115_3924 NC_011353.1 3636564 3636716 D identified by glimmer; hypothetical protein 3636564..3636716 Escherichia coli O157:H7 str. EC4115 6971162 YP_002272147.1 CDS ECH74115_3925 NC_011353.1 3636703 3637887 D identified by match to protein family HMM PF07690; major facilitator family transporter 3636703..3637887 Escherichia coli O157:H7 str. EC4115 6970190 YP_002272148.1 CDS ECH74115_3926 NC_011353.1 3638056 3638748 D identified by match to protein family HMM PF03591; transporter branched chain amino acid exporter (LIV-E) family 3638056..3638748 Escherichia coli O157:H7 str. EC4115 6969494 YP_002272149.1 CDS ECH74115_3927 NC_011353.1 3638738 3639073 D hypothetical protein 3638738..3639073 Escherichia coli O157:H7 str. EC4115 6970148 YP_002272150.1 CDS mprA NC_011353.1 3639164 3639694 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3639164..3639694 Escherichia coli O157:H7 str. EC4115 6969615 YP_002272151.1 CDS ECH74115_3929 NC_011353.1 3639722 3639856 R identified by glimmer; hypothetical protein complement(3639722..3639856) Escherichia coli O157:H7 str. EC4115 6972096 YP_002272152.1 CDS emrA NC_011353.1 3639809 3640993 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998; multidrug resistance protein A 3639809..3640993 Escherichia coli O157:H7 str. EC4115 6970935 YP_002272153.1 CDS emrB NC_011353.1 3641010 3642548 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; multidrug resistance protein B 3641010..3642548 Escherichia coli O157:H7 str. EC4115 6967614 YP_002272154.1 CDS luxS NC_011353.1 3642612 3643127 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(3642612..3643127) Escherichia coli O157:H7 str. EC4115 6967157 YP_002272155.1 CDS gshA NC_011353.1 3643277 3644833 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(3643277..3644833) Escherichia coli O157:H7 str. EC4115 6972324 YP_002272156.1 CDS ECH74115_3935 NC_011353.1 3644906 3645334 R hypothetical protein complement(3644906..3645334) Escherichia coli O157:H7 str. EC4115 6968884 YP_002272157.1 CDS ECH74115_3936 NC_011353.1 3645331 3645897 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(3645331..3645897) Escherichia coli O157:H7 str. EC4115 6967816 YP_002272158.1 CDS csrA NC_011353.1 3647125 3647310 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(3647125..3647310) Escherichia coli O157:H7 str. EC4115 6972396 YP_002272159.1 CDS ECH74115_3943 NC_011353.1 3647420 3647536 D identified by glimmer; hypothetical protein 3647420..3647536 Escherichia coli O157:H7 str. EC4115 6971118 YP_002272160.1 CDS alaS NC_011353.1 3647545 3650175 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(3647545..3650175) Escherichia coli O157:H7 str. EC4115 6970116 YP_002272161.1 CDS recX NC_011353.1 3650303 3650803 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(3650303..3650803) Escherichia coli O157:H7 str. EC4115 6969869 YP_002272162.1 CDS recA NC_011353.1 3650871 3651932 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(3650871..3651932) Escherichia coli O157:H7 str. EC4115 6968887 YP_002272163.1 CDS ECH74115_3947 NC_011353.1 3652012 3652509 R identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A complement(3652012..3652509) Escherichia coli O157:H7 str. EC4115 6968281 YP_002272164.1 CDS mltB NC_011353.1 3652654 3653739 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(3652654..3653739) Escherichia coli O157:H7 str. EC4115 6967514 YP_002272165.1 CDS ECH74115_3949 NC_011353.1 3653870 3654007 R identified by glimmer; hypothetical protein complement(3653870..3654007) Escherichia coli O157:H7 str. EC4115 6970661 YP_002272166.1 CDS srlB NC_011353.1 3655525 3655896 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3655525..3655896 Escherichia coli O157:H7 str. EC4115 6967170 YP_002272167.1 CDS srlD NC_011353.1 3655900 3656679 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3655900..3656679 Escherichia coli O157:H7 str. EC4115 6971782 YP_002272168.1 CDS gutM NC_011353.1 3656785 3657144 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3656785..3657144 Escherichia coli O157:H7 str. EC4115 6972056 YP_002272169.1 CDS srlR NC_011353.1 3657211 3657984 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3657211..3657984 Escherichia coli O157:H7 str. EC4115 6970150 YP_002272170.1 CDS gutQ NC_011353.1 3657977 3658942 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3657977..3658942 Escherichia coli O157:H7 str. EC4115 6969541 YP_002272171.1 CDS norR NC_011353.1 3658939 3660453 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(3658939..3660453) Escherichia coli O157:H7 str. EC4115 6967299 YP_002272172.1 CDS norV NC_011353.1 3660640 3662079 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3660640..3662079 Escherichia coli O157:H7 str. EC4115 6970859 YP_002272173.1 CDS norW NC_011353.1 3662076 3663209 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3662076..3663209 Escherichia coli O157:H7 str. EC4115 6970705 YP_002272174.1 CDS hypF NC_011353.1 3663337 3665637 R identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143; carbamoyltransferase HypF complement(3663337..3665637) Escherichia coli O157:H7 str. EC4115 6970084 YP_002272175.1 CDS ECH74115_3963 NC_011353.1 3665742 3666269 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(3665742..3666269) Escherichia coli O157:H7 str. EC4115 6968711 YP_002272176.1 CDS ECH74115_3964 NC_011353.1 3666247 3666414 R identified by glimmer; hypothetical protein complement(3666247..3666414) Escherichia coli O157:H7 str. EC4115 6968092 YP_002272177.1 CDS ascG NC_011353.1 3666418 3667470 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator AscG complement(3666418..3667470) Escherichia coli O157:H7 str. EC4115 6968059 YP_002272178.1 CDS ascF NC_011353.1 3667688 3669145 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 3667688..3669145 Escherichia coli O157:H7 str. EC4115 6967437 YP_002272179.1 CDS ascB NC_011353.1 3669154 3670578 D identified by match to protein family HMM PF00232; cryptic 6-phospho-beta-glucosidase 3669154..3670578 Escherichia coli O157:H7 str. EC4115 6966883 YP_002272180.1 CDS hycI NC_011353.1 3670702 3671172 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3670702..3671172) Escherichia coli O157:H7 str. EC4115 6971260 YP_002272181.1 CDS ECH74115_3969 NC_011353.1 3671165 3671575 R identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein complement(3671165..3671575) Escherichia coli O157:H7 str. EC4115 6971230 YP_002272182.1 CDS hycG NC_011353.1 3671572 3672339 R identified by match to protein family HMM PF01058; formate hydrogenlyase subunit G complement(3671572..3672339) Escherichia coli O157:H7 str. EC4115 6971156 YP_002272183.1 CDS hycF NC_011353.1 3672339 3672881 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3672339..3672881) Escherichia coli O157:H7 str. EC4115 6967661 YP_002272184.1 CDS hycE NC_011353.1 3672891 3674621 R identified by match to protein family HMM PF00329; match to protein family HMM PF00346; formate hydrogenlyase subunit E complement(3672891..3674621) Escherichia coli O157:H7 str. EC4115 6967056 YP_002272185.1 CDS hycD NC_011353.1 3674618 3675541 R identified by match to protein family HMM PF00146; formate hydrogenlyase subunit D complement(3674618..3675541) Escherichia coli O157:H7 str. EC4115 6971781 YP_002272186.1 CDS hycC NC_011353.1 3675544 3677370 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3675544..3677370) Escherichia coli O157:H7 str. EC4115 6971017 YP_002272187.1 CDS hycB NC_011353.1 3677367 3677978 R identified by match to protein family HMM PF00037; formate hydrogenlyase subunit B complement(3677367..3677978) Escherichia coli O157:H7 str. EC4115 6971145 YP_002272188.1 CDS hycA NC_011353.1 3678103 3678564 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3678103..3678564) Escherichia coli O157:H7 str. EC4115 6970170 YP_002272189.1 CDS ECH74115_3977 NC_011353.1 3678598 3678735 R identified by glimmer; hypothetical protein complement(3678598..3678735) Escherichia coli O157:H7 str. EC4115 6969530 YP_002272190.1 CDS hypA NC_011353.1 3678764 3679126 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3678764..3679126 Escherichia coli O157:H7 str. EC4115 6968528 YP_002272191.1 CDS hypB NC_011353.1 3679130 3680002 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3679130..3680002 Escherichia coli O157:H7 str. EC4115 6968621 YP_002272192.1 CDS hypC2 NC_011353.1 3679993 3680265 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3679993..3680265 Escherichia coli O157:H7 str. EC4115 6967985 YP_002272193.1 CDS hypD NC_011353.1 3680265 3681386 D identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075; hydrogenase expression/formation protein HypD 3680265..3681386 Escherichia coli O157:H7 str. EC4115 6969187 YP_002272194.1 CDS hypE NC_011353.1 3681383 3682393 D identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124; hydrogenase expression/formation protein HypE 3681383..3682393 Escherichia coli O157:H7 str. EC4115 6967485 YP_002272195.1 CDS fhlA NC_011353.1 3682467 3684545 D identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; formate hydrogenlyase transcriptional activator 3682467..3684545 Escherichia coli O157:H7 str. EC4115 6967917 YP_002272196.1 CDS ECH74115_3984 NC_011353.1 3684582 3684935 R hypothetical protein complement(3684582..3684935) Escherichia coli O157:H7 str. EC4115 6966961 YP_002272197.1 CDS ECH74115_3985 NC_011353.1 3685012 3685146 R identified by glimmer; hypothetical protein complement(3685012..3685146) Escherichia coli O157:H7 str. EC4115 6971681 YP_002272198.1 CDS mutS NC_011353.1 3685222 3687783 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3685222..3687783 Escherichia coli O157:H7 str. EC4115 6971425 YP_002272199.1 CDS pphB NC_011353.1 3687889 3688545 D identified by match to protein family HMM PF00149; serine/threonine-specific protein phosphatase 2 3687889..3688545 Escherichia coli O157:H7 str. EC4115 6970290 YP_002272200.1 CDS kpdD NC_011353.1 3688586 3688822 R 4-hydroxybenzoate decarboxylase subunit D complement(3688586..3688822) Escherichia coli O157:H7 str. EC4115 6969662 YP_002272201.1 CDS kpdC NC_011353.1 3688833 3690260 R identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148; 4-hydroxybenzoate decarboxylase subunit C complement(3688833..3690260) Escherichia coli O157:H7 str. EC4115 6967454 YP_002272202.1 CDS kpdB NC_011353.1 3690260 3690853 R identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421; 4-hydroxybenzoate decarboxylase subunit B complement(3690260..3690853) Escherichia coli O157:H7 str. EC4115 6966833 YP_002272203.1 CDS ECH74115_3991 NC_011353.1 3691000 3691407 D identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3691000..3691407 Escherichia coli O157:H7 str. EC4115 6968587 YP_002272204.1 CDS rpoS NC_011353.1 3691527 3692519 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(3691527..3692519) Escherichia coli O157:H7 str. EC4115 6967777 YP_002272205.1 CDS nlpD NC_011353.1 3692582 3693673 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3692582..3693673) Escherichia coli O157:H7 str. EC4115 6966757 YP_002272206.1 CDS pcm NC_011353.1 3693813 3694439 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3693813..3694439) Escherichia coli O157:H7 str. EC4115 6971699 YP_002272207.1 CDS surE NC_011353.1 3694433 3695194 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3694433..3695194) Escherichia coli O157:H7 str. EC4115 6970394 YP_002272208.1 CDS truD NC_011353.1 3695175 3696224 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3695175..3696224) Escherichia coli O157:H7 str. EC4115 6969573 YP_002272209.1 CDS ispF NC_011353.1 3696221 3696700 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase complement(3696221..3696700) Escherichia coli O157:H7 str. EC4115 6970012 YP_002272210.1 CDS ispD NC_011353.1 3696700 3697410 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3696700..3697410) Escherichia coli O157:H7 str. EC4115 6969179 YP_002272211.1 CDS ftsB NC_011353.1 3697429 3697740 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3697429..3697740) Escherichia coli O157:H7 str. EC4115 6968841 YP_002272212.1 CDS ECH74115_4001 NC_011353.1 3697934 3698257 R hypothetical protein complement(3697934..3698257) Escherichia coli O157:H7 str. EC4115 6968161 YP_002272213.1 CDS cysC NC_011353.1 3698307 3698912 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3698307..3698912) Escherichia coli O157:H7 str. EC4115 6971850 YP_002272214.1 CDS cysN NC_011353.1 3698912 3700339 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3698912..3700339) Escherichia coli O157:H7 str. EC4115 6970539 YP_002272215.1 CDS cysD NC_011353.1 3700341 3701249 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3700341..3701249) Escherichia coli O157:H7 str. EC4115 6971339 YP_002272216.1 CDS iap NC_011353.1 3701501 3702538 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 3701501..3702538 Escherichia coli O157:H7 str. EC4115 6972209 YP_002272217.1 CDS ECH74115_4006 NC_011353.1 3702775 3702891 D identified by glimmer; hypothetical protein 3702775..3702891 Escherichia coli O157:H7 str. EC4115 6966573 YP_002272218.1 CDS ECH74115_4007 NC_011353.1 3702928 3703221 R identified by match to protein family HMM PF09707; match to protein family HMM TIGR01873; hypothetical protein complement(3702928..3703221) Escherichia coli O157:H7 str. EC4115 6967400 YP_002272219.1 CDS cas1 NC_011353.1 3703218 3704141 R identified by match to protein family HMM TIGR00287; match to protein family HMM TIGR03638; CRISPR-associated protein Cas1 complement(3703218..3704141) Escherichia coli O157:H7 str. EC4115 6968155 YP_002272220.1 CDS cse3 NC_011353.1 3704138 3704788 R identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907; CRISPR-associated protein, Cse3 family complement(3704138..3704788) Escherichia coli O157:H7 str. EC4115 6968934 YP_002272221.1 CDS cas5e NC_011353.1 3704770 3705516 R identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593; CRISPR-associated protein Cas5 complement(3704770..3705516) Escherichia coli O157:H7 str. EC4115 6970641 YP_002272222.1 CDS cse4 NC_011353.1 3705527 3706582 R identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869; CRISPR-associated protein, Cse4 family complement(3705527..3706582) Escherichia coli O157:H7 str. EC4115 6967722 YP_002272223.1 CDS cse2 NC_011353.1 3706594 3707130 R identified by match to protein family HMM PF09485; match to protein family HMM TIGR02548; Cse2 family CRISPR-associated protein complement(3706594..3707130) Escherichia coli O157:H7 str. EC4115 6971068 YP_002272224.1 CDS cse1 NC_011353.1 3707127 3708689 R identified by match to protein family HMM PF09481; match to protein family HMM TIGR02547; Cse1 family CRISPR-associated protein complement(3707127..3708689) Escherichia coli O157:H7 str. EC4115 6968976 YP_002272225.1 CDS cas3 NC_011353.1 3708787 3711486 R identified by match to protein family HMM TIGR01587; CRISPR-associated helicase Cas3 complement(3708787..3711486) Escherichia coli O157:H7 str. EC4115 6966553 YP_002272226.1 CDS cysH NC_011353.1 3712094 3712828 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3712094..3712828) Escherichia coli O157:H7 str. EC4115 6972254 YP_002272227.1 CDS cysI NC_011353.1 3712902 3714614 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3712902..3714614) Escherichia coli O157:H7 str. EC4115 6970800 YP_002272228.1 CDS cysJ NC_011353.1 3714614 3716413 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3714614..3716413) Escherichia coli O157:H7 str. EC4115 6971249 YP_002272229.1 CDS ECH74115_4019 NC_011353.1 3716626 3716739 R identified by glimmer; hypothetical protein complement(3716626..3716739) Escherichia coli O157:H7 str. EC4115 6971988 YP_002272230.1 CDS queD NC_011353.1 3716732 3717094 D identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367; queuosine biosynthesis protein QueD 3716732..3717094 Escherichia coli O157:H7 str. EC4115 6966872 YP_002272231.1 CDS ECH74115_4021 NC_011353.1 3717172 3718443 D identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 3717172..3718443 Escherichia coli O157:H7 str. EC4115 6967326 YP_002272232.1 CDS ECH74115_4022 NC_011353.1 3718434 3718694 D ferredoxin 3718434..3718694 Escherichia coli O157:H7 str. EC4115 6967996 YP_002272233.1 CDS ECH74115_4023 NC_011353.1 3718711 3719286 D identified by match to protein family HMM PF04309; glycerol-3-phosphate responsive antiterminator 3718711..3719286 Escherichia coli O157:H7 str. EC4115 6969134 YP_002272234.1 CDS ECH74115_4026 NC_011353.1 3720291 3721070 R identified by match to protein family HMM PF01012; electron transfer flavoprotein complement(3720291..3721070) Escherichia coli O157:H7 str. EC4115 6967714 YP_002272235.1 CDS ECH74115_4029 NC_011353.1 3722478 3723932 R identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD binding domain-containing protein complement(3722478..3723932) Escherichia coli O157:H7 str. EC4115 6969393 YP_002272236.1 CDS ECH74115_4030 NC_011353.1 3724002 3724787 R identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase complement(3724002..3724787) Escherichia coli O157:H7 str. EC4115 6970371 YP_002272237.1 CDS ECH74115_4031 NC_011353.1 3725106 3726383 D identified by match to protein family HMM PF07690; major facilitator family transporter 3725106..3726383 Escherichia coli O157:H7 str. EC4115 6968495 YP_002272238.1 CDS ECH74115_4032 NC_011353.1 3726410 3727888 D identified by match to protein family HMM PF00370; match to protein family HMM PF02782; carbohydrate kinase, FGGY family protein 3726410..3727888 Escherichia coli O157:H7 str. EC4115 6971947 YP_002272239.1 CDS ECH74115_4033 NC_011353.1 3728952 3729623 R hypothetical protein complement(3728952..3729623) Escherichia coli O157:H7 str. EC4115 6970270 YP_002272240.1 CDS ECH74115_4034 NC_011353.1 3729904 3730398 D identified by match to protein family HMM PF04011; LemA family protein 3729904..3730398 Escherichia coli O157:H7 str. EC4115 6969561 YP_002272241.1 CDS ECH74115_4036 NC_011353.1 3731166 3731318 D hypothetical protein 3731166..3731318 Escherichia coli O157:H7 str. EC4115 6967988 YP_002272242.1 CDS ECH74115_4037 NC_011353.1 3731320 3732468 D identified by match to protein family HMM PF04536; hypothetical protein 3731320..3732468 Escherichia coli O157:H7 str. EC4115 6967660 YP_002272243.1 CDS ECH74115_4038 NC_011353.1 3732474 3733379 D identified by match to protein family HMM PF04536; hypothetical protein 3732474..3733379 Escherichia coli O157:H7 str. EC4115 6967038 YP_002272244.1 CDS eno NC_011353.1 3733439 3734737 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3733439..3734737) Escherichia coli O157:H7 str. EC4115 6970928 YP_002272245.1 CDS pyrG NC_011353.1 3734825 3736462 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3734825..3736462) Escherichia coli O157:H7 str. EC4115 6971550 YP_002272246.1 CDS mazG NC_011353.1 3736690 3737481 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase complement(3736690..3737481) Escherichia coli O157:H7 str. EC4115 6969840 YP_002272247.1 CDS chpA NC_011353.1 3737552 3737887 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3737552..3737887) Escherichia coli O157:H7 str. EC4115 6971969 YP_002272248.1 CDS chpR NC_011353.1 3737887 3738135 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(3737887..3738135) Escherichia coli O157:H7 str. EC4115 6971867 YP_002272249.1 CDS relA NC_011353.1 3738213 3740447 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3738213..3740447) Escherichia coli O157:H7 str. EC4115 6972047 YP_002272250.1 CDS rumA NC_011353.1 3740495 3741796 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3740495..3741796) Escherichia coli O157:H7 str. EC4115 6971254 YP_002272251.1 CDS barA NC_011353.1 3741853 3744609 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3741853..3744609 Escherichia coli O157:H7 str. EC4115 6970811 YP_002272252.1 CDS ECH74115_4047 NC_011353.1 3744842 3746182 R identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247; glucarate dehydratase complement(3744842..3746182) Escherichia coli O157:H7 str. EC4115 6970013 YP_002272253.1 CDS gudP NC_011353.1 3747545 3748897 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; glucarate permease complement(3747545..3748897) Escherichia coli O157:H7 str. EC4115 6967524 YP_002272254.1 CDS ECH74115_4051 NC_011353.1 3748992 3749117 R identified by glimmer; hypothetical protein complement(3748992..3749117) Escherichia coli O157:H7 str. EC4115 6971975 YP_002272255.1 CDS ECH74115_4052 NC_011353.1 3749111 3749239 D identified by glimmer; hypothetical protein 3749111..3749239 Escherichia coli O157:H7 str. EC4115 6970060 YP_002272256.1 CDS ECH74115_4053 NC_011353.1 3749332 3749781 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3749332..3749781) Escherichia coli O157:H7 str. EC4115 6969279 YP_002272257.1 CDS truC NC_011353.1 3749799 3750581 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3749799..3750581) Escherichia coli O157:H7 str. EC4115 6968832 YP_002272258.1 CDS ECH74115_4055 NC_011353.1 3750581 3750910 R identified by match to protein family HMM PF04287; hypothetical protein complement(3750581..3750910) Escherichia coli O157:H7 str. EC4115 6967959 YP_002272259.1 CDS ECH74115_4057 NC_011353.1 3751532 3752077 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3751532..3752077) Escherichia coli O157:H7 str. EC4115 6972308 YP_002272260.1 CDS queF NC_011353.1 3752145 3752993 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3752145..3752993 Escherichia coli O157:H7 str. EC4115 6971894 YP_002272261.1 CDS ECH74115_4059 NC_011353.1 3753105 3754469 D identified by match to protein family HMM PF03641; hypothetical protein 3753105..3754469 Escherichia coli O157:H7 str. EC4115 6970975 YP_002272262.1 CDS ECH74115_4060 NC_011353.1 3755026 3756315 D identified by match to protein family HMM TIGR00814; serine transporter family protein 3755026..3756315 Escherichia coli O157:H7 str. EC4115 6970301 YP_002272263.1 CDS sdaB NC_011353.1 3756373 3757740 D identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine ammonia-lyase 2 3756373..3757740 Escherichia coli O157:H7 str. EC4115 6968449 YP_002272264.1 CDS xni NC_011353.1 3757852 3758607 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3757852..3758607 Escherichia coli O157:H7 str. EC4115 6967711 YP_002272265.1 CDS fucO NC_011353.1 3758662 3759813 R identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638; L-1,2-propanediol oxidoreductase complement(3758662..3759813) Escherichia coli O157:H7 str. EC4115 6969814 YP_002272266.1 CDS fucA NC_011353.1 3759838 3760485 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3759838..3760485) Escherichia coli O157:H7 str. EC4115 6970788 YP_002272267.1 CDS fucP NC_011353.1 3761032 3762348 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885; L-fucose transporter 3761032..3762348 Escherichia coli O157:H7 str. EC4115 6969480 YP_002272268.1 CDS fucI NC_011353.1 3762381 3764156 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3762381..3764156 Escherichia coli O157:H7 str. EC4115 6970181 YP_002272269.1 CDS fucK NC_011353.1 3764235 3765683 D identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628; L-fuculokinase 3764235..3765683 Escherichia coli O157:H7 str. EC4115 6971097 YP_002272270.1 CDS fucU NC_011353.1 3765685 3766107 D identified by match to protein family HMM PF05025; fucose operon protein FucU 3765685..3766107 Escherichia coli O157:H7 str. EC4115 6971728 YP_002272271.1 CDS fucR NC_011353.1 3766165 3766896 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3766165..3766896 Escherichia coli O157:H7 str. EC4115 6967478 YP_002272272.1 CDS ECH74115_4070 NC_011353.1 3766940 3768040 R RNA 2'-O-ribose methyltransferase complement(3766940..3768040) Escherichia coli O157:H7 str. EC4115 6968433 YP_002272273.1 CDS ECH74115_4071 NC_011353.1 3768033 3768428 R identified by match to protein family HMM PF04241; hypothetical protein complement(3768033..3768428) Escherichia coli O157:H7 str. EC4115 6969380 YP_002272274.1 CDS gcvA NC_011353.1 3768447 3769364 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3768447..3769364) Escherichia coli O157:H7 str. EC4115 6969824 YP_002272275.1 CDS ECH74115_4074 NC_011353.1 3769715 3769942 R identified by match to protein family HMM PF06004; lipoprotein complement(3769715..3769942) Escherichia coli O157:H7 str. EC4115 6972259 YP_002272276.1 CDS csdA NC_011353.1 3770134 3771339 D identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392; cysteine sulfinate desulfinase 3770134..3771339 Escherichia coli O157:H7 str. EC4115 6971927 YP_002272277.1 CDS csdE NC_011353.1 3771339 3771782 D identified by match to protein family HMM PF02657; match to protein family HMM TIGR03391; cysteine desulfuration protein CsdE 3771339..3771782 Escherichia coli O157:H7 str. EC4115 6968974 YP_002272278.1 CDS ECH74115_4077 NC_011353.1 3771833 3772633 R identified by match to protein family HMM PF00899; ThiF family protein complement(3771833..3772633) Escherichia coli O157:H7 str. EC4115 6966697 YP_002272279.1 CDS mltA NC_011353.1 3772878 3773945 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3772878..3773945) Escherichia coli O157:H7 str. EC4115 6968110 YP_002272280.1 CDS amiC NC_011353.1 3774554 3775807 R identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-L-alanine amidase AmiC complement(3774554..3775807) Escherichia coli O157:H7 str. EC4115 6972414 YP_002272281.1 CDS argA NC_011353.1 3776039 3777370 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3776039..3777370 Escherichia coli O157:H7 str. EC4115 6970042 YP_002272282.1 CDS recD NC_011353.1 3777432 3779258 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3777432..3779258) Escherichia coli O157:H7 str. EC4115 6970517 YP_002272283.1 CDS recB NC_011353.1 3779258 3782800 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3779258..3782800) Escherichia coli O157:H7 str. EC4115 6968714 YP_002272284.1 CDS ptrA NC_011353.1 3782793 3785681 R identified by match to protein family HMM PF00675; match to protein family HMM PF05193; protease III complement(3782793..3785681) Escherichia coli O157:H7 str. EC4115 6969226 YP_002272285.1 CDS recC NC_011353.1 3785857 3789225 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3785857..3789225) Escherichia coli O157:H7 str. EC4115 6968678 YP_002272286.1 CDS ppdC NC_011353.1 3789238 3789561 R identified by match to protein family HMM TIGR02532; hypothetical protein complement(3789238..3789561) Escherichia coli O157:H7 str. EC4115 6967655 YP_002272287.1 CDS ECH74115_4089 NC_011353.1 3789546 3789953 R hypothetical protein complement(3789546..3789953) Escherichia coli O157:H7 str. EC4115 6967573 YP_002272288.1 CDS ppdB NC_011353.1 3789950 3790513 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein complement(3789950..3790513) Escherichia coli O157:H7 str. EC4115 6968189 YP_002272289.1 CDS ppdA NC_011353.1 3790504 3790974 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein complement(3790504..3790974) Escherichia coli O157:H7 str. EC4115 6968807 YP_002272290.1 CDS thyA NC_011353.1 3791158 3791952 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3791158..3791952) Escherichia coli O157:H7 str. EC4115 6968581 YP_002272291.1 CDS lgt NC_011353.1 3791959 3792834 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3791959..3792834) Escherichia coli O157:H7 str. EC4115 6972079 YP_002272292.1 CDS ptsP NC_011353.1 3792985 3795231 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3792985..3795231) Escherichia coli O157:H7 str. EC4115 6969849 YP_002272293.1 CDS nudH NC_011353.1 3795244 3795774 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3795244..3795774) Escherichia coli O157:H7 str. EC4115 6971327 YP_002272294.1 CDS ECH74115_4097 NC_011353.1 3796219 3796380 D identified by glimmer; hypothetical protein 3796219..3796380 Escherichia coli O157:H7 str. EC4115 6968580 YP_002272295.1 CDS mutH NC_011353.1 3796459 3797148 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3796459..3797148 Escherichia coli O157:H7 str. EC4115 6972015 YP_002272296.1 CDS ECH74115_4099 NC_011353.1 3797217 3797930 D identified by match to protein family HMM PF03741; TerC family integral membrane protein 3797217..3797930 Escherichia coli O157:H7 str. EC4115 6971840 YP_002272297.1 CDS ECH74115_4100 NC_011353.1 3798068 3798286 D identified by match to protein family HMM PF06004; lipoprotein 3798068..3798286 Escherichia coli O157:H7 str. EC4115 6971031 YP_002272298.1 CDS tas NC_011353.1 3798394 3799434 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3798394..3799434 Escherichia coli O157:H7 str. EC4115 6967342 YP_002272299.1 CDS lplT NC_011353.1 3799466 3800659 R identified by match to protein family HMM PF07690; lysophospholipid transporter LplT complement(3799466..3800659) Escherichia coli O157:H7 str. EC4115 6968771 YP_002272300.1 CDS aas NC_011353.1 3800652 3802811 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3800652..3802811) Escherichia coli O157:H7 str. EC4115 6967941 YP_002272301.1 CDS galR NC_011353.1 3803397 3804428 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3803397..3804428 Escherichia coli O157:H7 str. EC4115 6972310 YP_002272302.1 CDS lysA NC_011353.1 3804435 3805697 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3804435..3805697) Escherichia coli O157:H7 str. EC4115 6969884 YP_002272303.1 CDS lysR NC_011353.1 3805819 3806754 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 3805819..3806754 Escherichia coli O157:H7 str. EC4115 6970422 YP_002272304.1 CDS ECH74115_4108 NC_011353.1 3806741 3807433 R identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035; racemase complement(3806741..3807433) Escherichia coli O157:H7 str. EC4115 6970927 YP_002272305.1 CDS araE NC_011353.1 3807562 3808980 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; arabinose-proton symporter complement(3807562..3808980) Escherichia coli O157:H7 str. EC4115 6968556 YP_002272306.1 CDS kduD NC_011353.1 3809295 3810056 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3809295..3810056) Escherichia coli O157:H7 str. EC4115 6971538 YP_002272307.1 CDS kduI NC_011353.1 3810086 3810922 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3810086..3810922) Escherichia coli O157:H7 str. EC4115 6971923 YP_002272308.1 CDS ECH74115_4113 NC_011353.1 3811209 3812390 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3811209..3812390) Escherichia coli O157:H7 str. EC4115 6970450 YP_002272309.1 CDS ECH74115_4114 NC_011353.1 3812645 3813874 D identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814; serine transporter family protein 3812645..3813874 Escherichia coli O157:H7 str. EC4115 6968524 YP_002272310.1 CDS ECH74115_4115 NC_011353.1 3814397 3814966 D hypothetical protein 3814397..3814966 Escherichia coli O157:H7 str. EC4115 6969077 YP_002272311.1 CDS ECH74115_4116 NC_011353.1 3815300 3816109 D identified by match to protein family HMM PF00486; transcriptional regulator 3815300..3816109 Escherichia coli O157:H7 str. EC4115 6966580 YP_002272312.1 CDS ECH74115_4117 NC_011353.1 3816271 3816585 D hypothetical protein 3816271..3816585 Escherichia coli O157:H7 str. EC4115 6967810 YP_002272313.1 CDS ECH74115_4118 NC_011353.1 3816618 3816743 R identified by glimmer; hypothetical protein complement(3816618..3816743) Escherichia coli O157:H7 str. EC4115 6967537 YP_002272314.1 CDS ECH74115_4119 NC_011353.1 3817299 3817535 R identified by glimmer; hypothetical protein complement(3817299..3817535) Escherichia coli O157:H7 str. EC4115 6970615 YP_002272315.1 CDS ECH74115_4121 NC_011353.1 3818212 3818334 R identified by glimmer; hypothetical protein complement(3818212..3818334) Escherichia coli O157:H7 str. EC4115 6967205 YP_002272316.1 CDS ECH74115_4122 NC_011353.1 3818306 3818797 D identified by match to protein family HMM PF07720; hypothetical protein 3818306..3818797 Escherichia coli O157:H7 str. EC4115 6967520 YP_002272317.1 CDS ECH74115_4123 NC_011353.1 3819131 3820507 D identified by match to protein family HMM PF00486; match to protein family HMM PF07719; transcriptional regulator 3819131..3820507 Escherichia coli O157:H7 str. EC4115 6971278 YP_002272318.1 CDS ECH74115_4124 NC_011353.1 3820674 3820892 D hypothetical protein 3820674..3820892 Escherichia coli O157:H7 str. EC4115 6971573 YP_002272319.1 CDS ECH74115_4125 NC_011353.1 3820977 3821480 D identified by match to protein family HMM PF01464; lytic transglycosylase PilT 3820977..3821480 Escherichia coli O157:H7 str. EC4115 6969740 YP_002272320.1 CDS ECH74115_4126 NC_011353.1 3821499 3822131 R identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator complement(3821499..3822131) Escherichia coli O157:H7 str. EC4115 6968612 YP_002272321.1 CDS ECH74115_4127 NC_011353.1 3822110 3822277 R identified by glimmer; hypothetical protein complement(3822110..3822277) Escherichia coli O157:H7 str. EC4115 6969257 YP_002272322.1 CDS ECH74115_4128 NC_011353.1 3822354 3822785 R hypothetical protein complement(3822354..3822785) Escherichia coli O157:H7 str. EC4115 6968584 YP_002272323.1 CDS ECH74115_4130 NC_011353.1 3823004 3823159 R hypothetical protein complement(3823004..3823159) Escherichia coli O157:H7 str. EC4115 6970577 YP_002272324.1 CDS ECH74115_4131 NC_011353.1 3823601 3824335 R identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544; type III secretion apparatus lipoprotein EprK complement(3823601..3824335) Escherichia coli O157:H7 str. EC4115 6968538 YP_002272325.1 CDS eprJ NC_011353.1 3824332 3824664 R type III secretion apparatus protein EprJ complement(3824332..3824664) Escherichia coli O157:H7 str. EC4115 6969431 YP_002272326.1 CDS eprI NC_011353.1 3824684 3824923 R identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105; type III secretion apparatus needle protein complement(3824684..3824923) Escherichia coli O157:H7 str. EC4115 6970244 YP_002272327.1 CDS ECH74115_4135 NC_011353.1 3825680 3825817 R identified by glimmer; hypothetical protein complement(3825680..3825817) Escherichia coli O157:H7 str. EC4115 6971863 YP_002272328.1 CDS ECH74115_4136 NC_011353.1 3826375 3826875 D identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 3826375..3826875 Escherichia coli O157:H7 str. EC4115 6966940 YP_002272329.1 CDS ECH74115_4137 NC_011353.1 3827232 3828353 R Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; surface presentation of antigens protein SpaS complement(3827232..3828353) Escherichia coli O157:H7 str. EC4115 6967744 YP_002272330.1 CDS epaQ NC_011353.1 3829131 3829391 R identified by match to protein family HMM PF01313; match to protein family HMM TIGR01403; type III secretion apparatus protein EpaQ complement(3829131..3829391) Escherichia coli O157:H7 str. EC4115 6971290 YP_002272331.1 CDS spaP NC_011353.1 3829402 3830067 R part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP complement(3829402..3830067) Escherichia coli O157:H7 str. EC4115 6970997 YP_002272332.1 CDS ECH74115_4143 NC_011353.1 3831003 3831572 R type III secretion apparatus protein complement(3831003..3831572) Escherichia coli O157:H7 str. EC4115 6969457 YP_002272333.1 CDS ECH74115_4145 NC_011353.1 3831856 3832323 R protein EivI complement(3831856..3832323) Escherichia coli O157:H7 str. EC4115 6968604 YP_002272334.1 CDS ECH74115_4146 NC_011353.1 3832304 3833596 R Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase; ATP synthase SpaL complement(3832304..3833596) Escherichia coli O157:H7 str. EC4115 6967647 YP_002272335.1 CDS ECH74115_4147 NC_011353.1 3833628 3835688 R identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399; type III secretion protein, HrcV family complement(3833628..3835688) Escherichia coli O157:H7 str. EC4115 6967062 YP_002272336.1 CDS ECH74115_4148 NC_011353.1 3835681 3836826 R identified by match to protein family HMM PF02523; match to protein family HMM TIGR02568; protein EivE complement(3835681..3836826) Escherichia coli O157:H7 str. EC4115 6969113 YP_002272337.1 CDS ECH74115_4149 NC_011353.1 3836831 3838534 R identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516; type III secretion outer membrane pore, YscC/HrcC family complement(3836831..3838534) Escherichia coli O157:H7 str. EC4115 6972017 YP_002272338.1 CDS ECH74115_4150 NC_011353.1 3838531 3839280 R identified by match to protein family HMM PF00165; protein EivF complement(3838531..3839280) Escherichia coli O157:H7 str. EC4115 6966705 YP_002272339.1 CDS ECH74115_4151 NC_011353.1 3839626 3839805 R hypothetical protein complement(3839626..3839805) Escherichia coli O157:H7 str. EC4115 6967304 YP_002272340.1 CDS ECH74115_4155 NC_011353.1 3841863 3842618 R identified by match to protein family HMM PF01476; match to protein family HMM PF01551; peptidase, M23B family complement(3841863..3842618) Escherichia coli O157:H7 str. EC4115 6972382 YP_002272341.1 CDS xdhA NC_011353.1 3843034 3845331 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3843034..3845331 Escherichia coli O157:H7 str. EC4115 6970033 YP_002272342.1 CDS xdhB NC_011353.1 3845342 3846220 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3845342..3846220 Escherichia coli O157:H7 str. EC4115 6967881 YP_002272343.1 CDS xdhC NC_011353.1 3846217 3846696 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3846217..3846696 Escherichia coli O157:H7 str. EC4115 6968690 YP_002272344.1 CDS ECH74115_4159 NC_011353.1 3846736 3848514 R identified by match to protein family HMM PF00158; match to protein family HMM PF02954; Fis family sigma-54 dependent transcriptional regulator complement(3846736..3848514) Escherichia coli O157:H7 str. EC4115 6971683 YP_002272345.1 CDS ECH74115_4160 NC_011353.1 3848990 3850180 D identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316; aspartate/ornithine carbamoyltransferase family protein 3848990..3850180 Escherichia coli O157:H7 str. EC4115 6972241 YP_002272346.1 CDS ECH74115_4161 NC_011353.1 3850238 3851434 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3850238..3851434 Escherichia coli O157:H7 str. EC4115 6969989 YP_002272347.1 CDS ECH74115_4162 NC_011353.1 3851492 3852703 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3851492..3852703 Escherichia coli O157:H7 str. EC4115 6969559 YP_002272348.1 CDS hyuA NC_011353.1 3852744 3854141 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3852744..3854141 Escherichia coli O157:H7 str. EC4115 6966881 YP_002272349.1 CDS ECH74115_4164 NC_011353.1 3854189 3855121 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3854189..3855121 Escherichia coli O157:H7 str. EC4115 6967499 YP_002272350.1 CDS ECH74115_4165 NC_011353.1 3855162 3856787 R identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309; xanthine dehydrogenase accessory factor complement(3855162..3856787) Escherichia coli O157:H7 str. EC4115 6971302 YP_002272351.1 CDS ECH74115_4166 NC_011353.1 3856835 3857605 R identified by match to protein family HMM TIGR03172; hypothetical protein complement(3856835..3857605) Escherichia coli O157:H7 str. EC4115 6971944 YP_002272352.1 CDS ECH74115_4167 NC_011353.1 3857708 3858286 D identified by match to protein family HMM TIGR03310; hypothetical protein 3857708..3858286 Escherichia coli O157:H7 str. EC4115 6970541 YP_002272353.1 CDS ECH74115_4168 NC_011353.1 3858608 3861706 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3858608..3861706 Escherichia coli O157:H7 str. EC4115 6971463 YP_002272354.1 CDS ssnA NC_011353.1 3861709 3863037 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3861709..3863037 Escherichia coli O157:H7 str. EC4115 6969203 YP_002272355.1 CDS ECH74115_4170 NC_011353.1 3863087 3863866 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3863087..3863866 Escherichia coli O157:H7 str. EC4115 6969333 YP_002272356.1 CDS ECH74115_4171 NC_011353.1 3863863 3866733 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3863863..3866733 Escherichia coli O157:H7 str. EC4115 6968193 YP_002272357.1 CDS ECH74115_4172 NC_011353.1 3866898 3868298 D identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine/uracil permease family protein 3866898..3868298 Escherichia coli O157:H7 str. EC4115 6970237 YP_002272358.1 CDS guaD NC_011353.1 3868316 3869632 D Catalyzes the deamination of guanine; guanine deaminase 3868316..3869632 Escherichia coli O157:H7 str. EC4115 6971810 YP_002272359.1 CDS ECH74115_4174 NC_011353.1 3869668 3871035 D identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inorganic anion transporter sulfate permease (SulP) family 3869668..3871035 Escherichia coli O157:H7 str. EC4115 6969772 YP_002272360.1 CDS ECH74115_4176 NC_011353.1 3871559 3873484 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3871559..3873484) Escherichia coli O157:H7 str. EC4115 6966902 YP_002272361.1 CDS ECH74115_4177 NC_011353.1 3873785 3875362 D identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 3873785..3875362 Escherichia coli O157:H7 str. EC4115 6969345 YP_002272362.1 CDS ECH74115_4178 NC_011353.1 3875364 3875489 D identified by glimmer; hypothetical protein 3875364..3875489 Escherichia coli O157:H7 str. EC4115 6968518 YP_002272363.1 CDS idi NC_011353.1 3875612 3876160 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3875612..3876160 Escherichia coli O157:H7 str. EC4115 6968210 YP_002272364.1 CDS lysS NC_011353.1 3876203 3877720 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3876203..3877720) Escherichia coli O157:H7 str. EC4115 6968074 YP_002272365.1 CDS ECH74115_4182 NC_011353.1 3878612 3878767 D hypothetical protein 3878612..3878767 Escherichia coli O157:H7 str. EC4115 6966777 YP_002272366.1 CDS recJ NC_011353.1 3878919 3880652 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3878919..3880652) Escherichia coli O157:H7 str. EC4115 6967880 YP_002272367.1 CDS dsbC NC_011353.1 3880658 3881368 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3880658..3881368) Escherichia coli O157:H7 str. EC4115 6971244 YP_002272368.1 CDS xerD NC_011353.1 3881393 3882289 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3881393..3882289) Escherichia coli O157:H7 str. EC4115 6970965 YP_002272369.1 CDS fldB NC_011353.1 3882401 3882922 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3882401..3882922 Escherichia coli O157:H7 str. EC4115 6969993 YP_002272370.1 CDS ECH74115_4187 NC_011353.1 3882962 3883348 R identified by match to protein family HMM PF07254; hypothetical protein complement(3882962..3883348) Escherichia coli O157:H7 str. EC4115 6969666 YP_002272371.1 CDS ECH74115_4188 NC_011353.1 3883350 3883616 R identified by match to protein family HMM PF03937; hypothetical protein complement(3883350..3883616) Escherichia coli O157:H7 str. EC4115 6970438 YP_002272372.1 CDS ECH74115_4189 NC_011353.1 3883609 3883782 D identified by glimmer; hypothetical protein 3883609..3883782 Escherichia coli O157:H7 str. EC4115 6968306 YP_002272373.1 CDS ECH74115_4190 NC_011353.1 3883859 3884839 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3883859..3884839 Escherichia coli O157:H7 str. EC4115 6971019 YP_002272374.1 CDS ECH74115_4191 NC_011353.1 3884916 3885575 R identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin III family channel protein complement(3884916..3885575) Escherichia coli O157:H7 str. EC4115 6971864 YP_002272375.1 CDS ECH74115_4192 NC_011353.1 3885739 3886050 R identified by match to protein family HMM PF04266; hypothetical protein complement(3885739..3886050) Escherichia coli O157:H7 str. EC4115 6971917 YP_002272376.1 CDS bglA NC_011353.1 3886089 3887528 D identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase 3886089..3887528 Escherichia coli O157:H7 str. EC4115 6969906 YP_002272377.1 CDS gcvP NC_011353.1 3887694 3890567 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3887694..3890567) Escherichia coli O157:H7 str. EC4115 6970726 YP_002272378.1 CDS gcvH NC_011353.1 3890685 3891074 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3890685..3891074) Escherichia coli O157:H7 str. EC4115 6968606 YP_002272379.1 CDS gcvT NC_011353.1 3891098 3892192 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3891098..3892192) Escherichia coli O157:H7 str. EC4115 6968673 YP_002272380.1 CDS ECH74115_4197 NC_011353.1 3892368 3892496 R hypothetical protein complement(3892368..3892496) Escherichia coli O157:H7 str. EC4115 6966729 YP_002272381.1 CDS ECH74115_4198 NC_011353.1 3892453 3892566 D identified by glimmer; hypothetical protein 3892453..3892566 Escherichia coli O157:H7 str. EC4115 6967557 YP_002272382.1 CDS ECH74115_4199 NC_011353.1 3892640 3893842 R identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988; hypothetical protein complement(3892640..3893842) Escherichia coli O157:H7 str. EC4115 6967944 YP_002272383.1 CDS ubiH NC_011353.1 3893866 3895044 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3893866..3895044) Escherichia coli O157:H7 str. EC4115 6968429 YP_002272384.1 CDS pepP NC_011353.1 3895041 3896366 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3895041..3896366) Escherichia coli O157:H7 str. EC4115 6970341 YP_002272385.1 CDS ECH74115_4202 NC_011353.1 3896392 3896970 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3896392..3896970) Escherichia coli O157:H7 str. EC4115 6969652 YP_002272386.1 CDS ECH74115_4203 NC_011353.1 3897138 3897467 D identified by match to protein family HMM PF05164; Z-ring-associated protein 3897138..3897467 Escherichia coli O157:H7 str. EC4115 6969152 YP_002272387.1 CDS ECH74115_4205 NC_011353.1 3897713 3898315 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3897713..3898315 Escherichia coli O157:H7 str. EC4115 6972261 YP_002272388.1 CDS serA NC_011353.1 3899097 3900329 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3899097..3900329) Escherichia coli O157:H7 str. EC4115 6972309 YP_002272389.1 CDS ECH74115_4209 NC_011353.1 3900358 3900480 D identified by glimmer; hypothetical protein 3900358..3900480 Escherichia coli O157:H7 str. EC4115 6969588 YP_002272390.1 CDS rpiA NC_011353.1 3900584 3901243 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3900584..3901243) Escherichia coli O157:H7 str. EC4115 6971551 YP_002272391.1 CDS argP NC_011353.1 3901626 3902519 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3901626..3902519 Escherichia coli O157:H7 str. EC4115 6967243 YP_002272392.1 CDS scpA NC_011353.1 3902723 3904867 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3902723..3904867 Escherichia coli O157:H7 str. EC4115 6970508 YP_002272393.1 CDS ECH74115_4214 NC_011353.1 3904860 3905855 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3904860..3905855 Escherichia coli O157:H7 str. EC4115 6971390 YP_002272394.1 CDS ECH74115_4215 NC_011353.1 3905866 3906651 D catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3905866..3906651 Escherichia coli O157:H7 str. EC4115 6967709 YP_002272395.1 CDS ECH74115_4217 NC_011353.1 3906675 3908153 D identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458; acetyl-CoA hydrolase/transferase 3906675..3908153 Escherichia coli O157:H7 str. EC4115 6971568 YP_002272396.1 CDS ECH74115_4219 NC_011353.1 3909213 3909953 R identified by match to protein family HMM PF04402; hypothetical protein complement(3909213..3909953) Escherichia coli O157:H7 str. EC4115 6969481 YP_002272397.1 CDS argO NC_011353.1 3910046 3910681 R Involved in the export of arginine; arginine exporter protein complement(3910046..3910681) Escherichia coli O157:H7 str. EC4115 6969064 YP_002272398.1 CDS mscS NC_011353.1 3910820 3911680 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3910820..3911680) Escherichia coli O157:H7 str. EC4115 6968244 YP_002272399.1 CDS fbaA NC_011353.1 3912038 3913117 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3912038..3913117) Escherichia coli O157:H7 str. EC4115 6972040 YP_002272400.1 CDS pgk NC_011353.1 3913332 3914495 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3913332..3914495) Escherichia coli O157:H7 str. EC4115 6968756 YP_002272401.1 CDS epd NC_011353.1 3914545 3915564 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3914545..3915564) Escherichia coli O157:H7 str. EC4115 6967663 YP_002272402.1 CDS ECH74115_4225 NC_011353.1 3915936 3916367 D identified by match to protein family HMM PF03479; hypothetical protein 3915936..3916367 Escherichia coli O157:H7 str. EC4115 6967221 YP_002272403.1 CDS ECH74115_4226 NC_011353.1 3916390 3916968 D hypothetical protein 3916390..3916968 Escherichia coli O157:H7 str. EC4115 6971272 YP_002272404.1 CDS ECH74115_4227 NC_011353.1 3916969 3917676 D hypothetical protein 3916969..3917676 Escherichia coli O157:H7 str. EC4115 6972092 YP_002272405.1 CDS ECH74115_4228 NC_011353.1 3917664 3918341 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3917664..3918341 Escherichia coli O157:H7 str. EC4115 6968970 YP_002272406.1 CDS ECH74115_4230 NC_011353.1 3918335 3919012 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3918335..3919012 Escherichia coli O157:H7 str. EC4115 6970527 YP_002272407.1 CDS frcK NC_011353.1 3918984 3919697 R fructose transport system kinase complement(3918984..3919697) Escherichia coli O157:H7 str. EC4115 6969024 YP_002272408.1 CDS ECH74115_4231 NC_011353.1 3919694 3920203 R identified by match to protein family HMM PF05068; DNA-binding transcriptional regulator complement(3919694..3920203) Escherichia coli O157:H7 str. EC4115 6968214 YP_002272409.1 CDS glpX2 NC_011353.1 3920225 3921190 R identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330; fructose-1,6-bisphosphatase II-like protein complement(3920225..3921190) Escherichia coli O157:H7 str. EC4115 6967190 YP_002272410.1 CDS sorE NC_011353.1 3921187 3922464 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-sorbose 1-phosphate reductase complement(3921187..3922464) Escherichia coli O157:H7 str. EC4115 6967419 YP_002272411.1 CDS ECH74115_4234 NC_011353.1 3922479 3923867 R identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit cryptic EIICB complement(3922479..3923867) Escherichia coli O157:H7 str. EC4115 6968995 YP_002272412.1 CDS cmtB NC_011353.1 3923895 3924338 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3923895..3924338) Escherichia coli O157:H7 str. EC4115 6969867 YP_002272413.1 CDS ECH74115_4236 NC_011353.1 3924348 3924470 R identified by glimmer; hypothetical protein complement(3924348..3924470) Escherichia coli O157:H7 str. EC4115 6970463 YP_002272414.1 CDS tktA NC_011353.1 3924652 3926643 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3924652..3926643) Escherichia coli O157:H7 str. EC4115 6971447 YP_002272415.1 CDS ECH74115_4238 NC_011353.1 3926921 3927679 D identified by match to protein family HMM PF01435; peptidase, M48B family 3926921..3927679 Escherichia coli O157:H7 str. EC4115 6971499 YP_002272416.1 CDS speB NC_011353.1 3927885 3928805 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3927885..3928805) Escherichia coli O157:H7 str. EC4115 6972108 YP_002272417.1 CDS ECH74115_4240 NC_011353.1 3928941 3929672 R lipoprotein complement(3928941..3929672) Escherichia coli O157:H7 str. EC4115 6967291 YP_002272418.1 CDS speA NC_011353.1 3929818 3931716 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3929818..3931716) Escherichia coli O157:H7 str. EC4115 6968274 YP_002272419.1 CDS ECH74115_4242 NC_011353.1 3931803 3931934 R hypothetical protein complement(3931803..3931934) Escherichia coli O157:H7 str. EC4115 6969854 YP_002272420.1 CDS ECH74115_4243 NC_011353.1 3932269 3932394 D identified by glimmer; hypothetical protein 3932269..3932394 Escherichia coli O157:H7 str. EC4115 6968573 YP_002272421.1 CDS metK NC_011353.1 3932589 3933743 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3932589..3933743 Escherichia coli O157:H7 str. EC4115 6969377 YP_002272422.1 CDS ECH74115_4245 NC_011353.1 3933806 3934021 D identified by glimmer; hypothetical protein 3933806..3934021 Escherichia coli O157:H7 str. EC4115 6969825 YP_002272423.1 CDS galP NC_011353.1 3934180 3935574 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; galactose-proton symporter 3934180..3935574 Escherichia coli O157:H7 str. EC4115 6971256 YP_002272424.1 CDS sprT NC_011353.1 3935597 3936148 D identified by match to protein family HMM PF03926; hypothetical protein 3935597..3936148 Escherichia coli O157:H7 str. EC4115 6972042 YP_002272425.1 CDS endA NC_011353.1 3936243 3936950 D identified by match to protein family HMM PF04231; endonuclease I 3936243..3936950 Escherichia coli O157:H7 str. EC4115 6971762 YP_002272426.1 CDS rsmE NC_011353.1 3937030 3937761 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3937030..3937761 Escherichia coli O157:H7 str. EC4115 6967359 YP_002272427.1 CDS gshB NC_011353.1 3937774 3938721 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3937774..3938721 Escherichia coli O157:H7 str. EC4115 6967300 YP_002272428.1 CDS ECH74115_4251 NC_011353.1 3938833 3939396 D identified by match to protein family HMM PF02622; hypothetical protein 3938833..3939396 Escherichia coli O157:H7 str. EC4115 6968267 YP_002272429.1 CDS ECH74115_4252 NC_011353.1 3939396 3939812 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3939396..3939812 Escherichia coli O157:H7 str. EC4115 6968906 YP_002272430.1 CDS ECH74115_4253 NC_011353.1 3940003 3941028 R identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility family protein complement(3940003..3941028) Escherichia coli O157:H7 str. EC4115 6967508 YP_002272431.1 CDS ECH74115_4254 NC_011353.1 3941001 3941705 D identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044; pyridoxal phosphate enzyme, YggS family 3941001..3941705 Escherichia coli O157:H7 str. EC4115 6967532 YP_002272432.1 CDS ECH74115_4255 NC_011353.1 3941723 3942289 D identified by match to protein family HMM PF02325; hypothetical protein 3941723..3942289 Escherichia coli O157:H7 str. EC4115 6966732 YP_002272433.1 CDS ECH74115_4256 NC_011353.1 3942286 3942576 D identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; hypothetical protein 3942286..3942576 Escherichia coli O157:H7 str. EC4115 6971303 YP_002272434.1 CDS rdgB NC_011353.1 3942584 3943177 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3942584..3943177 Escherichia coli O157:H7 str. EC4115 6970498 YP_002272435.1 CDS ECH74115_4258 NC_011353.1 3943170 3944306 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3943170..3944306 Escherichia coli O157:H7 str. EC4115 6970781 YP_002272436.1 CDS ECH74115_4259 NC_011353.1 3944549 3945556 R identified by match to protein family HMM PF06717; hypothetical protein complement(3944549..3945556) Escherichia coli O157:H7 str. EC4115 6969947 YP_002272437.1 CDS ansB NC_011353.1 3945673 3946719 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3945673..3946719) Escherichia coli O157:H7 str. EC4115 6968817 YP_002272438.1 CDS ECH74115_4261 NC_011353.1 3946895 3947614 R hypothetical protein complement(3946895..3947614) Escherichia coli O157:H7 str. EC4115 6968005 YP_002272439.1 CDS ECH74115_4262 NC_011353.1 3947635 3947775 R hypothetical protein complement(3947635..3947775) Escherichia coli O157:H7 str. EC4115 6968219 YP_002272440.1 CDS ECH74115_4263 NC_011353.1 3947798 3948124 R identified by match to protein family HMM PF04320; hypothetical protein complement(3947798..3948124) Escherichia coli O157:H7 str. EC4115 6970119 YP_002272441.1 CDS trmB NC_011353.1 3948124 3948843 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3948124..3948843) Escherichia coli O157:H7 str. EC4115 6968663 YP_002272442.1 CDS mutY NC_011353.1 3949004 3950056 D identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; adenine DNA glycosylase 3949004..3950056 Escherichia coli O157:H7 str. EC4115 6969259 YP_002272443.1 CDS ECH74115_4266 NC_011353.1 3950084 3950359 D identified by match to protein family HMM PF04362; hypothetical protein 3950084..3950359 Escherichia coli O157:H7 str. EC4115 6966836 YP_002272444.1 CDS mltC NC_011353.1 3950424 3951503 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3950424..3951503 Escherichia coli O157:H7 str. EC4115 6967623 YP_002272445.1 CDS nupG NC_011353.1 3951705 3952961 D identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside permease NupG 3951705..3952961 Escherichia coli O157:H7 str. EC4115 6971932 YP_002272446.1 CDS speC NC_011353.1 3953011 3955146 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase complement(3953011..3955146) Escherichia coli O157:H7 str. EC4115 6971314 YP_002272447.1 CDS ECH74115_4270 NC_011353.1 3955544 3956251 D identified by match to protein family HMM PF04474; hypothetical protein 3955544..3956251 Escherichia coli O157:H7 str. EC4115 6970707 YP_002272448.1 CDS ECH74115_4272 NC_011353.1 3956630 3957895 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family protein 3956630..3957895 Escherichia coli O157:H7 str. EC4115 6972337 YP_002272449.1 CDS ECH74115_4273 NC_011353.1 3958012 3958632 R ISSfl4 ORF3 complement(3958012..3958632) Escherichia coli O157:H7 str. EC4115 6970064 YP_002272450.1 CDS ECH74115_4274 NC_011353.1 3958886 3959560 D identified by match to protein family HMM PF01527; ISSfl4 ORF1 3958886..3959560 Escherichia coli O157:H7 str. EC4115 6971828 YP_002272451.1 CDS ECH74115_4275 NC_011353.1 3959557 3959904 D identified by match to protein family HMM PF05717; ISSfl4 ORF2 3959557..3959904 Escherichia coli O157:H7 str. EC4115 6970140 YP_002272452.1 CDS ECH74115_4277 NC_011353.1 3961173 3962117 R DNA helicase II complement(3961173..3962117) Escherichia coli O157:H7 str. EC4115 6969371 YP_002272453.1 CDS ECH74115_4278 NC_011353.1 3962226 3962759 R identified by match to protein family HMM PF06316; outer membrane invasion protein complement(3962226..3962759) Escherichia coli O157:H7 str. EC4115 6967022 YP_002272454.1 CDS ECH74115_4279 NC_011353.1 3963347 3963523 R hypothetical protein complement(3963347..3963523) Escherichia coli O157:H7 str. EC4115 6967026 YP_002272455.1 CDS ECH74115_4282 NC_011353.1 3965355 3965474 R identified by glimmer; hypothetical protein complement(3965355..3965474) Escherichia coli O157:H7 str. EC4115 6969482 YP_002272456.1 CDS ECH74115_4284 NC_011353.1 3965754 3967403 D identified by match to protein family HMM PF07906; Ent protein 3965754..3967403 Escherichia coli O157:H7 str. EC4115 6966989 YP_002272457.1 CDS ECH74115_4285 NC_011353.1 3967476 3967622 R identified by glimmer; hypothetical protein complement(3967476..3967622) Escherichia coli O157:H7 str. EC4115 6967487 YP_002272458.1 CDS ECH74115_4286 NC_011353.1 3968011 3969000 D NleB 3968011..3969000 Escherichia coli O157:H7 str. EC4115 6966862 YP_002272459.1 CDS ECH74115_4287 NC_011353.1 3969049 3969723 D NleE 3969049..3969723 Escherichia coli O157:H7 str. EC4115 6968716 YP_002272460.1 CDS ECH74115_4291 NC_011353.1 3973861 3974208 D identified by match to protein family HMM PF05717; IS66 family element, orf2 3973861..3974208 Escherichia coli O157:H7 str. EC4115 6972123 YP_002272461.1 CDS ECH74115_4292 NC_011353.1 3974258 3975796 D identified by match to protein family HMM PF03050; IS66 family element, transposase 3974258..3975796 Escherichia coli O157:H7 str. EC4115 6971324 YP_002272462.1 CDS ECH74115_4293 NC_011353.1 3975864 3976022 D IS66 family transposase OrfA 3975864..3976022 Escherichia coli O157:H7 str. EC4115 6971328 YP_002272463.1 CDS ECH74115_4294 NC_011353.1 3976019 3976369 D identified by match to protein family HMM PF05717; IS66 family element, orf2 3976019..3976369 Escherichia coli O157:H7 str. EC4115 6968496 YP_002272464.1 CDS ECH74115_4298 NC_011353.1 3978077 3978247 D transposase InsF for insertion sequence IS3A/B/C/D/E/fA 3978077..3978247 Escherichia coli O157:H7 str. EC4115 6969327 YP_002272465.1 CDS ECH74115_4297 NC_011353.1 3978213 3978332 R identified by glimmer; hypothetical protein complement(3978213..3978332) Escherichia coli O157:H7 str. EC4115 6967747 YP_002272466.1 CDS ECH74115_4299 NC_011353.1 3978491 3979807 R identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 2 complement(3978491..3979807) Escherichia coli O157:H7 str. EC4115 6966972 YP_002272467.1 CDS gsp NC_011353.1 3980099 3981958 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3980099..3981958) Escherichia coli O157:H7 str. EC4115 6971018 YP_002272468.1 CDS ECH74115_4301 NC_011353.1 3982163 3983029 D YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 3982163..3983029 Escherichia coli O157:H7 str. EC4115 6971814 YP_002272469.1 CDS hybG NC_011353.1 3983152 3983400 R identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074; hydrogenase 2 accessory protein HypG complement(3983152..3983400) Escherichia coli O157:H7 str. EC4115 6969332 YP_002272470.1 CDS hypA1 NC_011353.1 3983413 3983754 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3983413..3983754) Escherichia coli O157:H7 str. EC4115 6970157 YP_002272471.1 CDS hybE NC_011353.1 3983747 3984235 R hydrogenase 2-specific chaperone complement(3983747..3984235) Escherichia coli O157:H7 str. EC4115 6967705 YP_002272472.1 CDS hybD NC_011353.1 3984228 3984722 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3984228..3984722) Escherichia coli O157:H7 str. EC4115 6967194 YP_002272473.1 CDS hybC NC_011353.1 3984722 3986425 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3984722..3986425) Escherichia coli O157:H7 str. EC4115 6968235 YP_002272474.1 CDS hybB NC_011353.1 3986422 3987600 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3986422..3987600) Escherichia coli O157:H7 str. EC4115 6968346 YP_002272475.1 CDS hybA NC_011353.1 3987590 3988576 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3987590..3988576) Escherichia coli O157:H7 str. EC4115 6970299 YP_002272476.1 CDS hybO NC_011353.1 3988579 3989697 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3988579..3989697) Escherichia coli O157:H7 str. EC4115 6969685 YP_002272477.1 CDS ECH74115_4310 NC_011353.1 3989681 3989809 D identified by glimmer; hypothetical protein 3989681..3989809 Escherichia coli O157:H7 str. EC4115 6971593 YP_002272478.1 CDS ECH74115_4311 NC_011353.1 3989886 3990173 R hypothetical protein complement(3989886..3990173) Escherichia coli O157:H7 str. EC4115 6970899 YP_002272479.1 CDS ECH74115_4312 NC_011353.1 3990292 3991179 R identified by match to protein family HMM PF01738; dienelactone hydrolase family protein complement(3990292..3991179) Escherichia coli O157:H7 str. EC4115 6968630 YP_002272480.1 CDS ECH74115_4313 NC_011353.1 3991336 3992376 D identified by match to protein family HMM PF00248; aldo-keto reductase 3991336..3992376 Escherichia coli O157:H7 str. EC4115 6967272 YP_002272481.1 CDS ECH74115_4314 NC_011353.1 3992416 3992910 R identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645; hypothetical protein complement(3992416..3992910) Escherichia coli O157:H7 str. EC4115 6971006 YP_002272482.1 CDS ECH74115_4315 NC_011353.1 3993101 3993985 D identified by match to protein family HMM PF00106; oxidoreductase 3993101..3993985 Escherichia coli O157:H7 str. EC4115 6970009 YP_002272483.1 CDS exbD NC_011353.1 3994257 3994682 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3994257..3994682) Escherichia coli O157:H7 str. EC4115 6970789 YP_002272484.1 CDS exbB NC_011353.1 3994689 3995423 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3994689..3995423) Escherichia coli O157:H7 str. EC4115 6970164 YP_002272485.1 CDS metC NC_011353.1 3995540 3996862 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3995540..3996862 Escherichia coli O157:H7 str. EC4115 6968159 YP_002272486.1 CDS ECH74115_4319 NC_011353.1 3997002 3997661 D identified by match to protein family HMM PF09335; hypothetical protein 3997002..3997661 Escherichia coli O157:H7 str. EC4115 6968941 YP_002272487.1 CDS ECH74115_4320 NC_011353.1 3997701 3998600 R identified by match to protein family HMM PF00165; match to protein family HMM PF06719; AraC family transcriptional regulator complement(3997701..3998600) Escherichia coli O157:H7 str. EC4115 6966968 YP_002272488.1 CDS ECH74115_4321 NC_011353.1 3998597 3998743 R identified by glimmer; hypothetical protein complement(3998597..3998743) Escherichia coli O157:H7 str. EC4115 6967754 YP_002272489.1 CDS yqhD NC_011353.1 3998794 3999957 D identified by match to protein family HMM PF00465; alcohol dehydrogenase yqhD 3998794..3999957 Escherichia coli O157:H7 str. EC4115 6971424 YP_002272490.1 CDS dkgA NC_011353.1 4000062 4000889 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 4000062..4000889 Escherichia coli O157:H7 str. EC4115 6970823 YP_002272491.1 CDS ECH74115_4326 NC_011353.1 4002060 4002317 D outer membrane lipoprotein 4002060..4002317 Escherichia coli O157:H7 str. EC4115 6966901 YP_002272492.1 CDS ECH74115_4327 NC_011353.1 4002360 4004579 R identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein complement(4002360..4004579) Escherichia coli O157:H7 str. EC4115 6967507 YP_002272493.1 CDS sufI NC_011353.1 4004690 4006102 R identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409; repressor protein for FtsI complement(4004690..4006102) Escherichia coli O157:H7 str. EC4115 6971013 YP_002272494.1 CDS plsC NC_011353.1 4006177 4006914 R identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(4006177..4006914) Escherichia coli O157:H7 str. EC4115 6971664 YP_002272495.1 CDS parC NC_011353.1 4007148 4009406 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(4007148..4009406) Escherichia coli O157:H7 str. EC4115 6969448 YP_002272496.1 CDS ECH74115_4331 NC_011353.1 4009544 4011151 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein complement(4009544..4011151) Escherichia coli O157:H7 str. EC4115 6970088 YP_002272497.1 CDS ECH74115_4332 NC_011353.1 4011260 4011742 R identified by match to protein family HMM PF06445; transcription activator effector binding domain/DNA gyrase inhibitor domain-containing protein complement(4011260..4011742) Escherichia coli O157:H7 str. EC4115 6967698 YP_002272498.1 CDS ECH74115_4333 NC_011353.1 4011795 4012187 R identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein complement(4011795..4012187) Escherichia coli O157:H7 str. EC4115 6968497 YP_002272499.1 CDS qseB NC_011353.1 4012339 4012998 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 4012339..4012998 Escherichia coli O157:H7 str. EC4115 6968878 YP_002272500.1 CDS qseC NC_011353.1 4012995 4014344 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein QseC 4012995..4014344 Escherichia coli O157:H7 str. EC4115 6969806 YP_002272501.1 CDS mdaB NC_011353.1 4014454 4015035 D identified by match to protein family HMM PF02525; modulator of drug activity B 4014454..4015035 Escherichia coli O157:H7 str. EC4115 6969726 YP_002272502.1 CDS ygiN NC_011353.1 4015066 4015380 D identified by match to protein family HMM PF03992; quinol monooxygenase YgiN 4015066..4015380 Escherichia coli O157:H7 str. EC4115 6971453 YP_002272503.1 CDS fitR NC_011353.1 4015425 4016312 R identified by match to protein family HMM PF01380; match to protein family HMM PF01418; iron transport system regulatory protein FitR complement(4015425..4016312) Escherichia coli O157:H7 str. EC4115 6972033 YP_002272504.1 CDS fitE NC_011353.1 4016309 4017256 R identified by match to protein family HMM PF01497; iron ABC transporter periplasmic iron-binding protein FitE complement(4016309..4017256) Escherichia coli O157:H7 str. EC4115 6970560 YP_002272505.1 CDS fitD NC_011353.1 4017267 4018304 R identified by match to protein family HMM PF01032; iron ABC transporter permease FitD complement(4017267..4018304) Escherichia coli O157:H7 str. EC4115 6968469 YP_002272506.1 CDS fitC NC_011353.1 4018313 4019296 R identified by match to protein family HMM PF01032; iron ABC transporter permease FitC complement(4018313..4019296) Escherichia coli O157:H7 str. EC4115 6971651 YP_002272507.1 CDS fitB NC_011353.1 4019293 4020102 R identified by match to protein family HMM PF00005; iron ABC transporter ATP binding protein FitB complement(4019293..4020102) Escherichia coli O157:H7 str. EC4115 6970098 YP_002272508.1 CDS fitA NC_011353.1 4020476 4022617 D identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; TonB-dependent outer membrane ferric coprogen receptor FitA 4020476..4022617 Escherichia coli O157:H7 str. EC4115 6966700 YP_002272509.1 CDS parE NC_011353.1 4022681 4024573 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(4022681..4024573) Escherichia coli O157:H7 str. EC4115 6970381 YP_002272510.1 CDS yqiA NC_011353.1 4024602 4025183 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(4024602..4025183) Escherichia coli O157:H7 str. EC4115 6970814 YP_002272511.1 CDS icc NC_011353.1 4025183 4026010 R identified by match to protein family HMM PF00149; match to protein family HMM PF08413; cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(4025183..4026010) Escherichia coli O157:H7 str. EC4115 6971626 YP_002272512.1 CDS ECH74115_4347 NC_011353.1 4026035 4026457 R identified by match to protein family HMM PF06853; hypothetical protein complement(4026035..4026457) Escherichia coli O157:H7 str. EC4115 6966784 YP_002272513.1 CDS nudF NC_011353.1 4026458 4027087 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF complement(4026458..4027087) Escherichia coli O157:H7 str. EC4115 6968806 YP_002272514.1 CDS tolC NC_011353.1 4027292 4028773 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 4027292..4028773 Escherichia coli O157:H7 str. EC4115 6970005 YP_002272515.1 CDS ECH74115_4350 NC_011353.1 4028921 4029592 D hypothetical protein 4028921..4029592 Escherichia coli O157:H7 str. EC4115 6972039 YP_002272516.1 CDS ECH74115_4351 NC_011353.1 4029598 4030758 D identified by match to protein family HMM PF03738; glutathionylspermidine synthase 4029598..4030758 Escherichia coli O157:H7 str. EC4115 6968773 YP_002272517.1 CDS ECH74115_4352 NC_011353.1 4030796 4031611 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(4030796..4031611) Escherichia coli O157:H7 str. EC4115 6967978 YP_002272518.1 CDS zupT NC_011353.1 4031727 4032500 D identified by match to protein family HMM PF02535; zinc transporter ZupT 4031727..4032500 Escherichia coli O157:H7 str. EC4115 6967586 YP_002272519.1 CDS ECH74115_4354 NC_011353.1 4032558 4032728 R hypothetical protein complement(4032558..4032728) Escherichia coli O157:H7 str. EC4115 6966865 YP_002272520.1 CDS ribB NC_011353.1 4032990 4033643 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(4032990..4033643) Escherichia coli O157:H7 str. EC4115 6968302 YP_002272521.1 CDS ECH74115_4357 NC_011353.1 4034017 4034316 D identified by match to protein family HMM PF04380; hypothetical protein 4034017..4034316 Escherichia coli O157:H7 str. EC4115 6968072 YP_002272522.1 CDS glgS NC_011353.1 4034351 4034551 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(4034351..4034551) Escherichia coli O157:H7 str. EC4115 6970324 YP_002272523.1 CDS ECH74115_4360 NC_011353.1 4035476 4037137 D identified by match to protein family HMM PF01145; hypothetical protein 4035476..4037137 Escherichia coli O157:H7 str. EC4115 6971415 YP_002272524.1 CDS hldE NC_011353.1 4037931 4039364 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(4037931..4039364) Escherichia coli O157:H7 str. EC4115 6972296 YP_002272525.1 CDS glnE NC_011353.1 4039412 4042252 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(4039412..4042252) Escherichia coli O157:H7 str. EC4115 6966661 YP_002272526.1 CDS ECH74115_4365 NC_011353.1 4042275 4043576 R identified by match to protein family HMM PF01928; match to protein family HMM PF05235; adenylate cyclase complement(4042275..4043576) Escherichia coli O157:H7 str. EC4115 6967367 YP_002272527.1 CDS ECH74115_4366 NC_011353.1 4043593 4043778 R identified by glimmer; hypothetical protein complement(4043593..4043778) Escherichia coli O157:H7 str. EC4115 6966664 YP_002272528.1 CDS ECH74115_4367 NC_011353.1 4043818 4044438 D signal transduction protein 4043818..4044438 Escherichia coli O157:H7 str. EC4115 6968746 YP_002272529.1 CDS cca NC_011353.1 4044502 4045740 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 4044502..4045740 Escherichia coli O157:H7 str. EC4115 6966669 YP_002272530.1 CDS bacA NC_011353.1 4045921 4046742 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(4045921..4046742) Escherichia coli O157:H7 str. EC4115 6967489 YP_002272531.1 CDS folB NC_011353.1 4046833 4047201 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(4046833..4047201) Escherichia coli O157:H7 str. EC4115 6971155 YP_002272532.1 CDS ECH74115_4371 NC_011353.1 4047307 4047924 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 4047307..4047924 Escherichia coli O157:H7 str. EC4115 6967966 YP_002272533.1 CDS ECH74115_4372 NC_011353.1 4047937 4048869 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(4047937..4048869) Escherichia coli O157:H7 str. EC4115 6968599 YP_002272534.1 CDS ddtA NC_011353.1 4049076 4049987 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 4049076..4049987 Escherichia coli O157:H7 str. EC4115 6966744 YP_002272535.1 CDS ttdB NC_011353.1 4049984 4050589 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 4049984..4050589 Escherichia coli O157:H7 str. EC4115 6967353 YP_002272536.1 CDS ECH74115_4375 NC_011353.1 4050638 4052101 D identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; anion transporter 4050638..4052101 Escherichia coli O157:H7 str. EC4115 6971238 YP_002272537.1 CDS gcp NC_011353.1 4052144 4053157 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(4052144..4053157) Escherichia coli O157:H7 str. EC4115 6972032 YP_002272538.1 CDS rpsU NC_011353.1 4053395 4053610 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 4053395..4053610 Escherichia coli O157:H7 str. EC4115 6971951 YP_002272539.1 CDS dnaG NC_011353.1 4053721 4055466 D synthesizes RNA primers at the replication forks; DNA primase 4053721..4055466 Escherichia coli O157:H7 str. EC4115 6967052 YP_002272540.1 CDS rpoD NC_011353.1 4055661 4057502 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 4055661..4057502 Escherichia coli O157:H7 str. EC4115 6967952 YP_002272541.1 CDS mug NC_011353.1 4057581 4058087 R identified by match to protein family HMM PF03167; G/U mismatch-specific DNA glycosylase complement(4057581..4058087) Escherichia coli O157:H7 str. EC4115 6970581 YP_002272542.1 CDS ECH74115_4383 NC_011353.1 4058341 4059105 R identified by match to protein family HMM PF04954; match to protein family HMM PF08021; siderophore-interacting protein complement(4058341..4059105) Escherichia coli O157:H7 str. EC4115 6972369 YP_002272543.1 CDS ECH74115_4384 NC_011353.1 4059393 4060016 D identified by match to protein family HMM PF03551; PadR family transcriptional regulator 4059393..4060016 Escherichia coli O157:H7 str. EC4115 6972204 YP_002272544.1 CDS aer NC_011353.1 4060170 4061690 R identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229; aerotaxis receptor complement(4060170..4061690) Escherichia coli O157:H7 str. EC4115 6971686 YP_002272545.1 CDS ECH74115_4386 NC_011353.1 4061881 4062009 R identified by glimmer; hypothetical protein complement(4061881..4062009) Escherichia coli O157:H7 str. EC4115 6966628 YP_002272546.1 CDS ygjG NC_011353.1 4062108 4063487 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 4062108..4063487 Escherichia coli O157:H7 str. EC4115 6967924 YP_002272547.1 CDS ECH74115_4388 NC_011353.1 4063529 4063861 R identified by match to protein family HMM PF01588; hypothetical protein complement(4063529..4063861) Escherichia coli O157:H7 str. EC4115 6968191 YP_002272548.1 CDS ebgR NC_011353.1 4064080 4065063 D identified by match to protein family HMM PF00356; match to protein family HMM PF00532; DNA-binding transcriptional repressor EbgR 4064080..4065063 Escherichia coli O157:H7 str. EC4115 6970267 YP_002272549.1 CDS ebgA NC_011353.1 4065247 4068339 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 4065247..4068339 Escherichia coli O157:H7 str. EC4115 6970808 YP_002272550.1 CDS ebgC NC_011353.1 4068336 4068785 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 4068336..4068785 Escherichia coli O157:H7 str. EC4115 6971585 YP_002272551.1 CDS ECH74115_4392 NC_011353.1 4068848 4070281 D identified by match to protein family HMM PF00324; amino acid permease family protein 4068848..4070281 Escherichia coli O157:H7 str. EC4115 6972075 YP_002272552.1 CDS ECH74115_4393 NC_011353.1 4070415 4071485 D hypothetical protein 4070415..4071485 Escherichia coli O157:H7 str. EC4115 6971423 YP_002272553.1 CDS ECH74115_4394 NC_011353.1 4071502 4073853 D glycosyl hydrolase 4071502..4073853 Escherichia coli O157:H7 str. EC4115 6967597 YP_002272554.1 CDS fadH NC_011353.1 4074379 4076397 D identified by match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992; 2,4-dienoyl-CoA reductase 4074379..4076397 Escherichia coli O157:H7 str. EC4115 6966981 YP_002272555.1 CDS ECH74115_4396 NC_011353.1 4076442 4076858 R identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein complement(4076442..4076858) Escherichia coli O157:H7 str. EC4115 6970307 YP_002272556.1 CDS ECH74115_4397 NC_011353.1 4076855 4077169 R hypothetical protein complement(4076855..4077169) Escherichia coli O157:H7 str. EC4115 6969684 YP_002272557.1 CDS ECH74115_4398 NC_011353.1 4077453 4078589 R identified by match to protein family HMM PF05175; match to protein family HMM PF08242; methyltransferase family protein complement(4077453..4078589) Escherichia coli O157:H7 str. EC4115 6968385 YP_002272558.1 CDS ECH74115_4399 NC_011353.1 4078674 4079177 D identified by match to protein family HMM PF01863; hypothetical protein 4078674..4079177 Escherichia coli O157:H7 str. EC4115 6970699 YP_002272559.1 CDS ECH74115_4400 NC_011353.1 4079254 4079946 D identified by match to protein family HMM PF02698; SanA protein 4079254..4079946 Escherichia coli O157:H7 str. EC4115 6969664 YP_002272560.1 CDS ECH74115_4401 NC_011353.1 4080025 4081011 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase, NAD binding 4080025..4081011 Escherichia coli O157:H7 str. EC4115 6971918 YP_002272561.1 CDS alx NC_011353.1 4081295 4082260 D identified by match to protein family HMM PF03741; protein Alx 4081295..4082260 Escherichia coli O157:H7 str. EC4115 6967462 YP_002272562.1 CDS sstT NC_011353.1 4082659 4083903 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 4082659..4083903 Escherichia coli O157:H7 str. EC4115 6966847 YP_002272563.1 CDS ECH74115_4405 NC_011353.1 4083908 4084459 R inner membrane protein complement(4083908..4084459) Escherichia coli O157:H7 str. EC4115 6967218 YP_002272564.1 CDS uxaA NC_011353.1 4084542 4086029 R identified by match to protein family HMM PF04295; match to protein family HMM PF08666; altronate dehydratase complement(4084542..4086029) Escherichia coli O157:H7 str. EC4115 6968023 YP_002272565.1 CDS uxaC NC_011353.1 4086044 4087456 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(4086044..4087456) Escherichia coli O157:H7 str. EC4115 6968269 YP_002272566.1 CDS exuT NC_011353.1 4087939 4089237 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; hexuronate transporter 4087939..4089237 Escherichia coli O157:H7 str. EC4115 6968820 YP_002272567.1 CDS exuR NC_011353.1 4089367 4090143 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 4089367..4090143 Escherichia coli O157:H7 str. EC4115 6968929 YP_002272568.1 CDS ECH74115_4410 NC_011353.1 4090488 4091150 D identified by match to protein family HMM PF09335; inner membrane protein 4090488..4091150 Escherichia coli O157:H7 str. EC4115 6969492 YP_002272569.1 CDS ECH74115_4411 NC_011353.1 4091169 4091537 D hypothetical protein 4091169..4091537 Escherichia coli O157:H7 str. EC4115 6969788 YP_002272570.1 CDS ECH74115_4412 NC_011353.1 4091684 4092052 D identified by match to protein family HMM PF06476; hypothetical protein 4091684..4092052 Escherichia coli O157:H7 str. EC4115 6971174 YP_002272571.1 CDS ECH74115_4413 NC_011353.1 4092090 4092395 D identified by match to protein family HMM PF05957; hypothetical protein 4092090..4092395 Escherichia coli O157:H7 str. EC4115 6970188 YP_002272572.1 CDS ECH74115_4414 NC_011353.1 4092398 4092802 D hypothetical protein 4092398..4092802 Escherichia coli O157:H7 str. EC4115 6971515 YP_002272573.1 CDS ECH74115_4415 NC_011353.1 4092792 4093091 D hypothetical protein 4092792..4093091 Escherichia coli O157:H7 str. EC4115 6972088 YP_002272574.1 CDS ECH74115_4416 NC_011353.1 4093187 4093669 D identified by match to protein family HMM PF07681; inner membrane protein YqjF 4093187..4093669 Escherichia coli O157:H7 str. EC4115 6966987 YP_002272575.1 CDS ECH74115_4417 NC_011353.1 4093739 4094725 D hypothetical protein 4093739..4094725 Escherichia coli O157:H7 str. EC4115 6968415 YP_002272576.1 CDS ECH74115_4418 NC_011353.1 4095017 4095382 D identified by match to protein family HMM PF05656; inner membrane protein YhaH 4095017..4095382 Escherichia coli O157:H7 str. EC4115 6968261 YP_002272577.1 CDS ECH74115_4419 NC_011353.1 4095623 4095979 D identified by match to protein family HMM PF05656; inner membrane protein 4095623..4095979 Escherichia coli O157:H7 str. EC4115 6970195 YP_002272578.1 CDS ECH74115_4420 NC_011353.1 4096030 4096926 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(4096030..4096926) Escherichia coli O157:H7 str. EC4115 6968168 YP_002272579.1 CDS ECH74115_4421 NC_011353.1 4097031 4097732 D identified by match to protein family HMM PF02678; pirin family protein 4097031..4097732 Escherichia coli O157:H7 str. EC4115 6969082 YP_002272580.1 CDS ECH74115_4422 NC_011353.1 4097752 4097919 D hypothetical protein 4097752..4097919 Escherichia coli O157:H7 str. EC4115 6967005 YP_002272581.1 CDS ECH74115_4423 NC_011353.1 4098053 4099363 R identified by match to protein family HMM PF06354; hypothetical protein complement(4098053..4099363) Escherichia coli O157:H7 str. EC4115 6971477 YP_002272582.1 CDS ECH74115_4424 NC_011353.1 4099391 4100722 R identified by match to protein family HMM TIGR00814; serine transporter family protein complement(4099391..4100722) Escherichia coli O157:H7 str. EC4115 6970657 YP_002272583.1 CDS tdcG NC_011353.1 4100997 4102367 R identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine ammonia-lyase TdcG complement(4100997..4102367) Escherichia coli O157:H7 str. EC4115 6968769 YP_002272584.1 CDS ECH74115_4426 NC_011353.1 4102433 4102822 R identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; hypothetical protein complement(4102433..4102822) Escherichia coli O157:H7 str. EC4115 6967995 YP_002272585.1 CDS pflB1 NC_011353.1 4102836 4105130 R identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase complement(4102836..4105130) Escherichia coli O157:H7 str. EC4115 6968016 YP_002272586.1 CDS tdcD NC_011353.1 4105164 4106372 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(4105164..4106372) Escherichia coli O157:H7 str. EC4115 6967446 YP_002272587.1 CDS tdcC NC_011353.1 4106398 4107729 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(4106398..4107729) Escherichia coli O157:H7 str. EC4115 6968553 YP_002272588.1 CDS tdcB NC_011353.1 4107751 4108740 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(4107751..4108740) Escherichia coli O157:H7 str. EC4115 6969172 YP_002272589.1 CDS tdcA NC_011353.1 4108839 4109777 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(4108839..4109777) Escherichia coli O157:H7 str. EC4115 6967011 YP_002272590.1 CDS tdcR NC_011353.1 4109966 4110310 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 4109966..4110310 Escherichia coli O157:H7 str. EC4115 6967618 YP_002272591.1 CDS ECH74115_4433 NC_011353.1 4110566 4111105 D identified by glimmer; hypothetical protein 4110566..4111105 Escherichia coli O157:H7 str. EC4115 6971141 YP_002272592.1 CDS ECH74115_4434 NC_011353.1 4111127 4112314 D hypothetical protein 4111127..4112314 Escherichia coli O157:H7 str. EC4115 6971763 YP_002272593.1 CDS garK NC_011353.1 4112943 4114088 R identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase complement(4112943..4114088) Escherichia coli O157:H7 str. EC4115 6972284 YP_002272594.1 CDS garR NC_011353.1 4114185 4115069 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(4114185..4115069) Escherichia coli O157:H7 str. EC4115 6970777 YP_002272595.1 CDS garL NC_011353.1 4115105 4115875 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(4115105..4115875) Escherichia coli O157:H7 str. EC4115 6970329 YP_002272596.1 CDS garP NC_011353.1 4115891 4117225 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; galactarate permease GarP complement(4115891..4117225) Escherichia coli O157:H7 str. EC4115 6968333 YP_002272597.1 CDS ECH74115_4440 NC_011353.1 4117246 4117371 D identified by glimmer; hypothetical protein 4117246..4117371 Escherichia coli O157:H7 str. EC4115 6972003 YP_002272598.1 CDS ECH74115_4441 NC_011353.1 4117434 4117553 D identified by glimmer; hypothetical protein 4117434..4117553 Escherichia coli O157:H7 str. EC4115 6971229 YP_002272599.1 CDS garD NC_011353.1 4117600 4119171 D identified by match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248; galactarate dehydratase 4117600..4119171 Escherichia coli O157:H7 str. EC4115 6967518 YP_002272600.1 CDS sohA NC_011353.1 4119515 4119655 D HtrA suppressor protein SohA 4119515..4119655 Escherichia coli O157:H7 str. EC4115 6966810 YP_002272601.1 CDS ECH74115_4444 NC_011353.1 4119655 4120119 D hypothetical protein 4119655..4120119 Escherichia coli O157:H7 str. EC4115 6968789 YP_002272602.1 CDS ECH74115_4445 NC_011353.1 4120174 4120983 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(4120174..4120983) Escherichia coli O157:H7 str. EC4115 6968107 YP_002272603.1 CDS ECH74115_4446 NC_011353.1 4121232 4122512 D identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; D-tagatose-bisphosphate aldolase non-catalytic subunit 4121232..4122512 Escherichia coli O157:H7 str. EC4115 6969785 YP_002272604.1 CDS agaV NC_011353.1 4122535 4123008 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4122535..4123008 Escherichia coli O157:H7 str. EC4115 6969329 YP_002272605.1 CDS agaW NC_011353.1 4123019 4123798 D identified by match to protein family HMM PF03609; PTS system N-acetylgalactosamine-specific transporter subunit IIC 4123019..4123798 Escherichia coli O157:H7 str. EC4115 6971176 YP_002272606.1 CDS agaE NC_011353.1 4123788 4124666 D identified by match to protein family HMM PF03613; PTS system N-acetylgalactosamine-specific, IID component 4123788..4124666 Escherichia coli O157:H7 str. EC4115 6970580 YP_002272607.1 CDS agaF NC_011353.1 4124684 4125118 D identified by match to protein family HMM PF03610; PTS system mannose/sorbose-specific transporter subunit IIA 4124684..4125118 Escherichia coli O157:H7 str. EC4115 6971609 YP_002272608.1 CDS nagA1 NC_011353.1 4125115 4126248 D identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 4125115..4126248 Escherichia coli O157:H7 str. EC4115 6970963 YP_002272609.1 CDS ECH74115_4452 NC_011353.1 4126366 4126500 D identified by glimmer; hypothetical protein 4126366..4126500 Escherichia coli O157:H7 str. EC4115 6970566 YP_002272610.1 CDS ECH74115_4453 NC_011353.1 4126599 4127753 D identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815; sugar isomerase 4126599..4127753 Escherichia coli O157:H7 str. EC4115 6969717 YP_002272611.1 CDS kbaY NC_011353.1 4127766 4128626 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 4127766..4128626 Escherichia coli O157:H7 str. EC4115 6971855 YP_002272612.1 CDS agaB NC_011353.1 4128793 4129269 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4128793..4129269 Escherichia coli O157:H7 str. EC4115 6971032 YP_002272613.1 CDS agaD NC_011353.1 4130101 4130892 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 4130101..4130892 Escherichia coli O157:H7 str. EC4115 6969427 YP_002272614.1 CDS ECH74115_4460 NC_011353.1 4132049 4132633 D identified by match to protein family HMM PF00419; type 1 fimbrial protein 4132049..4132633 Escherichia coli O157:H7 str. EC4115 6970464 YP_002272615.1 CDS ECH74115_4461 NC_011353.1 4132734 4133408 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; gram-negative pili assembly chaperone protein 4132734..4133408 Escherichia coli O157:H7 str. EC4115 6969689 YP_002272616.1 CDS ECH74115_4462 NC_011353.1 4133362 4135953 D identified by match to protein family HMM PF00577; fimbrial usher family protein 4133362..4135953 Escherichia coli O157:H7 str. EC4115 6972085 YP_002272617.1 CDS ECH74115_4465 NC_011353.1 4136740 4137600 R identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase family protein complement(4136740..4137600) Escherichia coli O157:H7 str. EC4115 6972221 YP_002272618.1 CDS ECH74115_4466 NC_011353.1 4137665 4139701 D identified by match to protein family HMM PF04348; lipoprotein 4137665..4139701 Escherichia coli O157:H7 str. EC4115 6969007 YP_002272619.1 CDS ECH74115_4467 NC_011353.1 4139659 4140054 D identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 4139659..4140054 Escherichia coli O157:H7 str. EC4115 6968151 YP_002272620.1 CDS diaA NC_011353.1 4140074 4140664 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 4140074..4140664 Escherichia coli O157:H7 str. EC4115 6969721 YP_002272621.1 CDS ECH74115_4469 NC_011353.1 4140674 4141249 D identified by match to protein family HMM PF04972; hypothetical protein 4140674..4141249 Escherichia coli O157:H7 str. EC4115 6969099 YP_002272622.1 CDS ECH74115_4470 NC_011353.1 4141363 4142403 R identified by match to protein family HMM PF03773; permease complement(4141363..4142403) Escherichia coli O157:H7 str. EC4115 6966609 YP_002272623.1 CDS ECH74115_4471 NC_011353.1 4142476 4143111 R identified by match to protein family HMM PF01370; NAD dependent epimerase/dehydratase family protein complement(4142476..4143111) Escherichia coli O157:H7 str. EC4115 6967401 YP_002272624.1 CDS ECH74115_4473 NC_011353.1 4143239 4143757 D identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; intracellular peptidase, PfpI family 4143239..4143757 Escherichia coli O157:H7 str. EC4115 6967762 YP_002272625.1 CDS ECH74115_4472 NC_011353.1 4143737 4144180 R hypothetical protein complement(4143737..4144180) Escherichia coli O157:H7 str. EC4115 6971891 YP_002272626.1 CDS ECH74115_4475 NC_011353.1 4144231 4144533 D identified by match to protein family HMM PF01541; GIY-YIG nuclease superfamily protein 4144231..4144533 Escherichia coli O157:H7 str. EC4115 6966643 YP_002272627.1 CDS ECH74115_4474 NC_011353.1 4144520 4145023 R identified by match to protein family HMM PF00583; GNAT family acetyltransferase complement(4144520..4145023) Escherichia coli O157:H7 str. EC4115 6969536 YP_002272628.1 CDS ECH74115_4476 NC_011353.1 4145017 4145541 R identified by match to protein family HMM PF02036; sterol-binding protein complement(4145017..4145541) Escherichia coli O157:H7 str. EC4115 6971275 YP_002272629.1 CDS ECH74115_4477 NC_011353.1 4145750 4146745 D identified by match to protein family HMM PF01136; U32 family peptidase 4145750..4146745 Escherichia coli O157:H7 str. EC4115 6969978 YP_002272630.1 CDS ECH74115_4478 NC_011353.1 4146754 4147632 D identified by match to protein family HMM PF01136; U32 family peptidase 4146754..4147632 Escherichia coli O157:H7 str. EC4115 6969291 YP_002272631.1 CDS ECH74115_4479 NC_011353.1 4147713 4148720 D identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558; hypothetical protein 4147713..4148720 Escherichia coli O157:H7 str. EC4115 6968491 YP_002272632.1 CDS mtr NC_011353.1 4148837 4150081 R tryptophan transporter of high affinity; tryptophan permease complement(4148837..4150081) Escherichia coli O157:H7 str. EC4115 6969777 YP_002272633.1 CDS deaD NC_011353.1 4150235 4152124 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(4150235..4152124) Escherichia coli O157:H7 str. EC4115 6970554 YP_002272634.1 CDS nlpI NC_011353.1 4152304 4153188 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(4152304..4153188) Escherichia coli O157:H7 str. EC4115 6971491 YP_002272635.1 CDS pnp NC_011353.1 4153297 4155432 R identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR03591; polynucleotide phosphorylase/polyadenylase complement(4153297..4155432) Escherichia coli O157:H7 str. EC4115 6970946 YP_002272636.1 CDS rpsO NC_011353.1 4155679 4155948 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(4155679..4155948) Escherichia coli O157:H7 str. EC4115 6972314 YP_002272637.1 CDS truB NC_011353.1 4156097 4157041 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(4156097..4157041) Escherichia coli O157:H7 str. EC4115 6966718 YP_002272638.1 CDS rbfA NC_011353.1 4157041 4157442 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(4157041..4157442) Escherichia coli O157:H7 str. EC4115 6970599 YP_002272639.1 CDS infB NC_011353.1 4157607 4160279 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(4157607..4160279) Escherichia coli O157:H7 str. EC4115 6968176 YP_002272640.1 CDS nusA NC_011353.1 4160304 4161791 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(4160304..4161791) Escherichia coli O157:H7 str. EC4115 6972185 YP_002272641.1 CDS ECH74115_4491 NC_011353.1 4161819 4162283 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(4161819..4162283) Escherichia coli O157:H7 str. EC4115 6969801 YP_002272642.1 CDS ECH74115_4493 NC_011353.1 4162694 4162816 D hypothetical protein 4162694..4162816 Escherichia coli O157:H7 str. EC4115 6972404 YP_002272643.1 CDS argG NC_011353.1 4162902 4164245 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 4162902..4164245 Escherichia coli O157:H7 str. EC4115 6971335 YP_002272644.1 CDS yhbX NC_011353.1 4164253 4165770 R identified by match to protein family HMM PF00884; inner membrane protein yhbX complement(4164253..4165770) Escherichia coli O157:H7 str. EC4115 6967552 YP_002272645.1 CDS secG NC_011353.1 4166438 4166770 R identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG complement(4166438..4166770) Escherichia coli O157:H7 str. EC4115 6972356 YP_002272646.1 CDS glmM NC_011353.1 4166998 4168335 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(4166998..4168335) Escherichia coli O157:H7 str. EC4115 6971993 YP_002272647.1 CDS folP NC_011353.1 4168328 4169176 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(4168328..4169176) Escherichia coli O157:H7 str. EC4115 6971255 YP_002272648.1 CDS hflB NC_011353.1 4169266 4171200 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(4169266..4171200) Escherichia coli O157:H7 str. EC4115 6968365 YP_002272649.1 CDS rrmJ NC_011353.1 4171300 4171929 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(4171300..4171929) Escherichia coli O157:H7 str. EC4115 6970612 YP_002272650.1 CDS ECH74115_4502 NC_011353.1 4172055 4172348 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 4172055..4172348 Escherichia coli O157:H7 str. EC4115 6966842 YP_002272651.1 CDS greA NC_011353.1 4172504 4172980 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(4172504..4172980) Escherichia coli O157:H7 str. EC4115 6968685 YP_002272652.1 CDS dacB NC_011353.1 4173228 4174661 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 4173228..4174661 Escherichia coli O157:H7 str. EC4115 6971630 YP_002272653.1 CDS obgE NC_011353.1 4174701 4175873 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(4174701..4175873) Escherichia coli O157:H7 str. EC4115 6970844 YP_002272654.1 CDS ECH74115_4506 NC_011353.1 4175889 4176854 R identified by match to protein family HMM PF00892; transporter complement(4175889..4176854) Escherichia coli O157:H7 str. EC4115 6970452 YP_002272655.1 CDS rpmA NC_011353.1 4176981 4177238 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(4176981..4177238) Escherichia coli O157:H7 str. EC4115 6971901 YP_002272656.1 CDS rplU NC_011353.1 4177259 4177570 R identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 complement(4177259..4177570) Escherichia coli O157:H7 str. EC4115 6968483 YP_002272657.1 CDS ispB NC_011353.1 4177829 4178800 D identified by match to protein family HMM PF00348; octaprenyl diphosphate synthase 4177829..4178800 Escherichia coli O157:H7 str. EC4115 6970655 YP_002272658.1 CDS sfsB NC_011353.1 4179029 4179307 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 4179029..4179307 Escherichia coli O157:H7 str. EC4115 6967209 YP_002272659.1 CDS murA NC_011353.1 4179355 4180614 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(4179355..4180614) Escherichia coli O157:H7 str. EC4115 6968752 YP_002272660.1 CDS ECH74115_4512 NC_011353.1 4180669 4180938 R identified by match to protein family HMM PF01722; BolA/YrbA family protein complement(4180669..4180938) Escherichia coli O157:H7 str. EC4115 6970954 YP_002272661.1 CDS yrbB NC_011353.1 4181083 4181376 R YrbB complement(4181083..4181376) Escherichia coli O157:H7 str. EC4115 6967495 YP_002272662.1 CDS ttg2D NC_011353.1 4181376 4182011 R identified by match to protein family HMM PF05494; toluene tolerance protein Ttg2D complement(4181376..4182011) Escherichia coli O157:H7 str. EC4115 6968609 YP_002272663.1 CDS ECH74115_4515 NC_011353.1 4182030 4182581 R identified by match to protein family HMM PF02470; Mce family protein complement(4182030..4182581) Escherichia coli O157:H7 str. EC4115 6967612 YP_002272664.1 CDS ECH74115_4516 NC_011353.1 4182586 4183368 R identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056; toluene ABC transporter permease complement(4182586..4183368) Escherichia coli O157:H7 str. EC4115 6970273 YP_002272665.1 CDS ECH74115_4517 NC_011353.1 4183376 4184185 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein complement(4183376..4184185) Escherichia coli O157:H7 str. EC4115 6970824 YP_002272666.1 CDS ECH74115_4518 NC_011353.1 4184395 4185372 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 4184395..4185372 Escherichia coli O157:H7 str. EC4115 6968951 YP_002272667.1 CDS kdsD NC_011353.1 4185386 4186372 D identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; D-arabinose 5-phosphate isomerase 4185386..4186372 Escherichia coli O157:H7 str. EC4115 6969409 YP_002272668.1 CDS kdsC NC_011353.1 4186393 4186959 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 4186393..4186959 Escherichia coli O157:H7 str. EC4115 6967685 YP_002272669.1 CDS ECH74115_4521 NC_011353.1 4186956 4187531 D identified by match to protein family HMM PF06835; hypothetical protein 4186956..4187531 Escherichia coli O157:H7 str. EC4115 6968150 YP_002272670.1 CDS lptA NC_011353.1 4187500 4188057 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 4187500..4188057 Escherichia coli O157:H7 str. EC4115 6972168 YP_002272671.1 CDS lptB NC_011353.1 4188064 4188789 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 4188064..4188789 Escherichia coli O157:H7 str. EC4115 6966974 YP_002272672.1 CDS rpoN NC_011353.1 4188837 4190270 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 4188837..4190270 Escherichia coli O157:H7 str. EC4115 6969117 YP_002272673.1 CDS yfiA NC_011353.1 4190293 4190580 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 4190293..4190580 Escherichia coli O157:H7 str. EC4115 6968204 YP_002272674.1 CDS ptsN NC_011353.1 4190698 4191189 D identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 4190698..4191189 Escherichia coli O157:H7 str. EC4115 6967802 YP_002272675.1 CDS ECH74115_4527 NC_011353.1 4191235 4192089 D identified by match to protein family HMM PF03668; hypothetical protein 4191235..4192089 Escherichia coli O157:H7 str. EC4115 6966947 YP_002272676.1 CDS ptsO NC_011353.1 4192086 4192358 D identified by match to protein family HMM PF00381; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr 4192086..4192358 Escherichia coli O157:H7 str. EC4115 6971628 YP_002272677.1 CDS ECH74115_4530 NC_011353.1 4192572 4193204 D hypothetical protein 4192572..4193204 Escherichia coli O157:H7 str. EC4115 6972097 YP_002272678.1 CDS mtgA NC_011353.1 4193201 4193929 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(4193201..4193929) Escherichia coli O157:H7 str. EC4115 6969455 YP_002272679.1 CDS elbB NC_011353.1 4193926 4194579 R identified by match to protein family HMM PF01965; isoprenoid biosynthesis protein complement(4193926..4194579) Escherichia coli O157:H7 str. EC4115 6970421 YP_002272680.1 CDS arcB NC_011353.1 4194809 4197145 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(4194809..4197145) Escherichia coli O157:H7 str. EC4115 6972292 YP_002272681.1 CDS ECH74115_4534 NC_011353.1 4197241 4198170 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212; radical SAM protein complement(4197241..4198170) Escherichia coli O157:H7 str. EC4115 6968926 YP_002272682.1 CDS gltB NC_011353.1 4198751 4203304 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 4198751..4203304 Escherichia coli O157:H7 str. EC4115 6967494 YP_002272683.1 CDS gltD NC_011353.1 4203317 4204735 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 4203317..4204735 Escherichia coli O157:H7 str. EC4115 6967734 YP_002272684.1 CDS ECH74115_4537 NC_011353.1 4204919 4205968 D identified by match to protein family HMM PF06250; hypothetical protein 4204919..4205968 Escherichia coli O157:H7 str. EC4115 6970840 YP_002272685.1 CDS ECH74115_4538 NC_011353.1 4206028 4206492 R identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein complement(4206028..4206492) Escherichia coli O157:H7 str. EC4115 6971596 YP_002272686.1 CDS ECH74115_4539 NC_011353.1 4206489 4207364 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(4206489..4207364) Escherichia coli O157:H7 str. EC4115 6966703 YP_002272687.1 CDS ECH74115_4540 NC_011353.1 4207361 4208050 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(4207361..4208050) Escherichia coli O157:H7 str. EC4115 6967849 YP_002272688.1 CDS nanT1 NC_011353.1 4208098 4209588 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891; sialic acid transporter complement(4208098..4209588) Escherichia coli O157:H7 str. EC4115 6967654 YP_002272689.1 CDS nanA NC_011353.1 4209697 4210590 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(4209697..4210590) Escherichia coli O157:H7 str. EC4115 6968595 YP_002272690.1 CDS nanR NC_011353.1 4210712 4211494 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(4210712..4211494) Escherichia coli O157:H7 str. EC4115 6969239 YP_002272691.1 CDS sspB NC_011353.1 4213282 4213779 R identified by match to protein family HMM PF04386; ClpXP protease specificity-enhancing factor complement(4213282..4213779) Escherichia coli O157:H7 str. EC4115 6970710 YP_002272692.1 CDS sspA NC_011353.1 4213785 4214423 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(4213785..4214423) Escherichia coli O157:H7 str. EC4115 6970048 YP_002272693.1 CDS rpsI NC_011353.1 4214818 4215210 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(4214818..4215210) Escherichia coli O157:H7 str. EC4115 6969041 YP_002272694.1 CDS rplM NC_011353.1 4215226 4215654 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(4215226..4215654) Escherichia coli O157:H7 str. EC4115 6967619 YP_002272695.1 CDS ECH74115_4549 NC_011353.1 4215873 4217000 R identified by match to protein family HMM PF03969; ATPase complement(4215873..4217000) Escherichia coli O157:H7 str. EC4115 6966767 YP_002272696.1 CDS ECH74115_4550 NC_011353.1 4217194 4217592 D identified by match to protein family HMM PF06295; cytochrome d ubiquinol oxidase subunit III 4217194..4217592 Escherichia coli O157:H7 str. EC4115 6971878 YP_002272697.1 CDS degQ NC_011353.1 4217746 4219113 D identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; serine endoprotease 4217746..4219113 Escherichia coli O157:H7 str. EC4115 6971099 YP_002272698.1 CDS degS NC_011353.1 4219203 4220270 D identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038; serine endoprotease 4219203..4220270 Escherichia coli O157:H7 str. EC4115 6970871 YP_002272699.1 CDS mdh NC_011353.1 4220334 4221272 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(4220334..4221272) Escherichia coli O157:H7 str. EC4115 6971500 YP_002272700.1 CDS argR NC_011353.1 4221707 4222177 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 4221707..4222177 Escherichia coli O157:H7 str. EC4115 6970727 YP_002272701.1 CDS ycfR NC_011353.1 4222491 4222805 D identified by match to protein family HMM PF07338; protein YcfR 4222491..4222805 Escherichia coli O157:H7 str. EC4115 6968864 YP_002272702.1 CDS ECH74115_4556 NC_011353.1 4222861 4223133 R hypothetical protein complement(4222861..4223133) Escherichia coli O157:H7 str. EC4115 6966811 YP_002272703.1 CDS aaeB NC_011353.1 4223225 4225192 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(4223225..4225192) Escherichia coli O157:H7 str. EC4115 6967422 YP_002272704.1 CDS aaeA NC_011353.1 4225198 4226127 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(4225198..4226127) Escherichia coli O157:H7 str. EC4115 6971533 YP_002272705.1 CDS aaeX NC_011353.1 4226135 4226407 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(4226135..4226407) Escherichia coli O157:H7 str. EC4115 6967139 YP_002272706.1 CDS aaeR NC_011353.1 4226521 4227450 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 4226521..4227450 Escherichia coli O157:H7 str. EC4115 6970588 YP_002272707.1 CDS tldD NC_011353.1 4227584 4229029 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(4227584..4229029) Escherichia coli O157:H7 str. EC4115 6971208 YP_002272708.1 CDS ECH74115_4562 NC_011353.1 4229185 4232985 R identified by match to protein family HMM TIGR02099; hypothetical protein complement(4229185..4232985) Escherichia coli O157:H7 str. EC4115 6969913 YP_002272709.1 CDS cafA NC_011353.1 4233053 4234522 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(4233053..4234522) Escherichia coli O157:H7 str. EC4115 6969641 YP_002272710.1 CDS maf1 NC_011353.1 4234512 4235105 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(4234512..4235105) Escherichia coli O157:H7 str. EC4115 6967533 YP_002272711.1 CDS mreD NC_011353.1 4235114 4235602 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(4235114..4235602) Escherichia coli O157:H7 str. EC4115 6971841 YP_002272712.1 CDS mreC NC_011353.1 4235602 4236705 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(4235602..4236705) Escherichia coli O157:H7 str. EC4115 6968158 YP_002272713.1 CDS mreB NC_011353.1 4236771 4237814 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(4236771..4237814) Escherichia coli O157:H7 str. EC4115 6968973 YP_002272714.1 CDS ECH74115_4568 NC_011353.1 4238119 4240059 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(4238119..4240059) Escherichia coli O157:H7 str. EC4115 6966599 YP_002272715.1 CDS ECH74115_4569 NC_011353.1 4240211 4241185 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823; quinone oxidoreductase, YhdH family 4240211..4241185 Escherichia coli O157:H7 str. EC4115 6967363 YP_002272716.1 CDS ECH74115_4570 NC_011353.1 4241222 4241386 D hypothetical protein 4241222..4241386 Escherichia coli O157:H7 str. EC4115 6972135 YP_002272717.1 CDS accB NC_011353.1 4242163 4242633 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 4242163..4242633 Escherichia coli O157:H7 str. EC4115 6970372 YP_002272718.1 CDS accC NC_011353.1 4242644 4243993 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 4242644..4243993 Escherichia coli O157:H7 str. EC4115 6971173 YP_002272719.1 CDS ECH74115_4574 NC_011353.1 4244102 4244344 D identified by match to protein family HMM PF06196; hypothetical protein 4244102..4244344 Escherichia coli O157:H7 str. EC4115 6967775 YP_002272720.1 CDS panF NC_011353.1 4244334 4245785 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 4244334..4245785 Escherichia coli O157:H7 str. EC4115 6970874 YP_002272721.1 CDS prmA NC_011353.1 4245797 4246678 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 4245797..4246678 Escherichia coli O157:H7 str. EC4115 6970122 YP_002272722.1 CDS dusB NC_011353.1 4247007 4247972 D identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 4247007..4247972 Escherichia coli O157:H7 str. EC4115 6970713 YP_002272723.1 CDS fis NC_011353.1 4247998 4248294 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 4247998..4248294 Escherichia coli O157:H7 str. EC4115 6967138 YP_002272724.1 CDS ECH74115_4579 NC_011353.1 4248379 4249263 D identified by match to protein family HMM PF01555; methyltransferase 4248379..4249263 Escherichia coli O157:H7 str. EC4115 6969346 YP_002272725.1 CDS ECH74115_4580 NC_011353.1 4249413 4249526 D hypothetical protein 4249413..4249526 Escherichia coli O157:H7 str. EC4115 6971251 YP_002272726.1 CDS ECH74115_4581 NC_011353.1 4249529 4250191 R identified by match to protein family HMM PF00440; match to protein family HMM PF08361; DNA-binding transcriptional regulator EnvR complement(4249529..4250191) Escherichia coli O157:H7 str. EC4115 6967753 YP_002272727.1 CDS acrE NC_011353.1 4250590 4251747 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein E 4250590..4251747 Escherichia coli O157:H7 str. EC4115 6969364 YP_002272728.1 CDS ECH74115_4585 NC_011353.1 4255161 4255382 D lipoprotein 4255161..4255382 Escherichia coli O157:H7 str. EC4115 6970893 YP_002272729.1 CDS ECH74115_4586 NC_011353.1 4255430 4255576 R identified by glimmer; hypothetical protein complement(4255430..4255576) Escherichia coli O157:H7 str. EC4115 6966948 YP_002272730.1 CDS ECH74115_4587 NC_011353.1 4255813 4256838 D amino acid ABC transporter periplasmic amino acid-binding protein 4255813..4256838 Escherichia coli O157:H7 str. EC4115 6967702 YP_002272731.1 CDS ECH74115_4588 NC_011353.1 4256906 4258087 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 4256906..4258087 Escherichia coli O157:H7 str. EC4115 6968512 YP_002272732.1 CDS ECH74115_4589 NC_011353.1 4258097 4259185 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; general L-amino acid transport system permease AapM 4258097..4259185 Escherichia coli O157:H7 str. EC4115 6969146 YP_002272733.1 CDS ECH74115_4590 NC_011353.1 4259211 4259537 D overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 4259211..4259537 Escherichia coli O157:H7 str. EC4115 6969447 YP_002272734.1 CDS ECH74115_4591 NC_011353.1 4259534 4260424 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 4259534..4260424 Escherichia coli O157:H7 str. EC4115 6970407 YP_002272735.1 CDS ECH74115_4592 NC_011353.1 4260521 4261279 D identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 4260521..4261279 Escherichia coli O157:H7 str. EC4115 6970570 YP_002272736.1 CDS ECH74115_4603 NC_011353.1 4267328 4267882 D hypothetical protein 4267328..4267882 Escherichia coli O157:H7 str. EC4115 6972265 YP_002272737.1 CDS ECH74115_4602 NC_011353.1 4267858 4268031 R identified by match to protein family HMM PF07369; hypothetical protein complement(4267858..4268031) Escherichia coli O157:H7 str. EC4115 6971962 YP_002272738.1 CDS aroE NC_011353.1 4268112 4268930 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(4268112..4268930) Escherichia coli O157:H7 str. EC4115 6967240 YP_002272739.1 CDS ECH74115_4605 NC_011353.1 4268935 4269507 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(4268935..4269507) Escherichia coli O157:H7 str. EC4115 6968455 YP_002272740.1 CDS ECH74115_4606 NC_011353.1 4269512 4270054 R identified by match to protein family HMM PF01396; topoisomerase DNA-binding C4 zinc finger domain-containing protein complement(4269512..4270054) Escherichia coli O157:H7 str. EC4115 6967436 YP_002272741.1 CDS smg NC_011353.1 4270083 4270556 R identified by match to protein family HMM PF04361; hypothetical protein complement(4270083..4270556) Escherichia coli O157:H7 str. EC4115 6969655 YP_002272742.1 CDS dprA NC_011353.1 4270528 4271652 R identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA complement(4270528..4271652) Escherichia coli O157:H7 str. EC4115 6968675 YP_002272743.1 CDS def NC_011353.1 4271782 4272291 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4271782..4272291 Escherichia coli O157:H7 str. EC4115 6966819 YP_002272744.1 CDS fmt NC_011353.1 4272306 4273253 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 4272306..4273253 Escherichia coli O157:H7 str. EC4115 6971559 YP_002272745.1 CDS rsmB NC_011353.1 4273299 4274588 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 4273299..4274588 Escherichia coli O157:H7 str. EC4115 6968117 YP_002272746.1 CDS trkA NC_011353.1 4274610 4275986 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 4274610..4275986 Escherichia coli O157:H7 str. EC4115 6967122 YP_002272747.1 CDS mscL NC_011353.1 4276116 4276526 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 4276116..4276526 Escherichia coli O157:H7 str. EC4115 6968550 YP_002272748.1 CDS zntR NC_011353.1 4276797 4277222 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(4276797..4277222) Escherichia coli O157:H7 str. EC4115 6969507 YP_002272749.1 CDS ECH74115_4615 NC_011353.1 4277233 4277601 R identified by match to protein family HMM PF09350; hypothetical protein complement(4277233..4277601) Escherichia coli O157:H7 str. EC4115 6971535 YP_002272750.1 CDS rplQ NC_011353.1 4277708 4278091 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(4277708..4278091) Escherichia coli O157:H7 str. EC4115 6971085 YP_002272751.1 CDS rpoA NC_011353.1 4278132 4279121 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(4278132..4279121) Escherichia coli O157:H7 str. EC4115 6971071 YP_002272752.1 CDS rpsD NC_011353.1 4279147 4279767 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(4279147..4279767) Escherichia coli O157:H7 str. EC4115 6967719 YP_002272753.1 CDS rpsK NC_011353.1 4279801 4280190 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(4279801..4280190) Escherichia coli O157:H7 str. EC4115 6967195 YP_002272754.1 CDS rpsM NC_011353.1 4280207 4280563 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(4280207..4280563) Escherichia coli O157:H7 str. EC4115 6969098 YP_002272755.1 CDS rpmJ NC_011353.1 4280710 4280826 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(4280710..4280826) Escherichia coli O157:H7 str. EC4115 6969722 YP_002272756.1 CDS secY NC_011353.1 4280858 4282189 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(4280858..4282189) Escherichia coli O157:H7 str. EC4115 6971391 YP_002272757.1 CDS rplO NC_011353.1 4282197 4282631 R late assembly protein; 50S ribosomal protein L15 complement(4282197..4282631) Escherichia coli O157:H7 str. EC4115 6972224 YP_002272758.1 CDS rpmD NC_011353.1 4282635 4282814 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(4282635..4282814) Escherichia coli O157:H7 str. EC4115 6966963 YP_002272759.1 CDS rpsE NC_011353.1 4282818 4283321 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(4282818..4283321) Escherichia coli O157:H7 str. EC4115 6968373 YP_002272760.1 CDS rplR NC_011353.1 4283336 4283689 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(4283336..4283689) Escherichia coli O157:H7 str. EC4115 6969190 YP_002272761.1 CDS rplF NC_011353.1 4283699 4284232 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(4283699..4284232) Escherichia coli O157:H7 str. EC4115 6968928 YP_002272762.1 CDS rpsH NC_011353.1 4284245 4284637 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(4284245..4284637) Escherichia coli O157:H7 str. EC4115 6969732 YP_002272763.1 CDS rpsN NC_011353.1 4284671 4284976 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(4284671..4284976) Escherichia coli O157:H7 str. EC4115 6971175 YP_002272764.1 CDS rplE NC_011353.1 4284991 4285530 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(4284991..4285530) Escherichia coli O157:H7 str. EC4115 6971796 YP_002272765.1 CDS rplX NC_011353.1 4285545 4285859 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(4285545..4285859) Escherichia coli O157:H7 str. EC4115 6967061 YP_002272766.1 CDS rplN NC_011353.1 4285870 4286241 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(4285870..4286241) Escherichia coli O157:H7 str. EC4115 6968692 YP_002272767.1 CDS rpsQ NC_011353.1 4286406 4286660 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(4286406..4286660) Escherichia coli O157:H7 str. EC4115 6968535 YP_002272768.1 CDS rpmC NC_011353.1 4286660 4286851 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(4286660..4286851) Escherichia coli O157:H7 str. EC4115 6968058 YP_002272769.1 CDS rplP NC_011353.1 4286851 4287261 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(4286851..4287261) Escherichia coli O157:H7 str. EC4115 6969805 YP_002272770.1 CDS rpsC NC_011353.1 4287274 4287975 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(4287274..4287975) Escherichia coli O157:H7 str. EC4115 6972243 YP_002272771.1 CDS rplV NC_011353.1 4287993 4288325 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(4287993..4288325) Escherichia coli O157:H7 str. EC4115 6971700 YP_002272772.1 CDS rpsS NC_011353.1 4288340 4288618 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(4288340..4288618) Escherichia coli O157:H7 str. EC4115 6971445 YP_002272773.1 CDS rplB NC_011353.1 4288635 4289456 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(4288635..4289456) Escherichia coli O157:H7 str. EC4115 6967266 YP_002272774.1 CDS rplW NC_011353.1 4289474 4289776 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(4289474..4289776) Escherichia coli O157:H7 str. EC4115 6966766 YP_002272775.1 CDS rplD NC_011353.1 4289773 4290378 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(4289773..4290378) Escherichia coli O157:H7 str. EC4115 6972004 YP_002272776.1 CDS rplC NC_011353.1 4290389 4291018 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(4290389..4291018) Escherichia coli O157:H7 str. EC4115 6969611 YP_002272777.1 CDS rpsJ NC_011353.1 4291051 4291362 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(4291051..4291362) Escherichia coli O157:H7 str. EC4115 6970081 YP_002272778.1 CDS ECH74115_4646 NC_011353.1 4291741 4292208 D peptidase, A24 (type IV prepilin peptidase) family 4291741..4292208 Escherichia coli O157:H7 str. EC4115 6970511 YP_002272779.1 CDS bfr NC_011353.1 4292205 4292681 R iron storage protein; bacterioferritin complement(4292205..4292681) Escherichia coli O157:H7 str. EC4115 6969173 YP_002272780.1 CDS bfd NC_011353.1 4292754 4292948 R identified by match to protein family HMM PF04324; bacterioferritin-associated ferredoxin complement(4292754..4292948) Escherichia coli O157:H7 str. EC4115 6968201 YP_002272781.1 CDS tuf2 NC_011353.1 4293131 4294315 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(4293131..4294315) Escherichia coli O157:H7 str. EC4115 6966737 YP_002272782.1 CDS fusA NC_011353.1 4294386 4296500 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(4294386..4296500) Escherichia coli O157:H7 str. EC4115 6967549 YP_002272783.1 CDS rpsG NC_011353.1 4296597 4297067 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(4296597..4297067) Escherichia coli O157:H7 str. EC4115 6967953 YP_002272784.1 CDS rpsL NC_011353.1 4297164 4297538 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(4297164..4297538) Escherichia coli O157:H7 str. EC4115 6968952 YP_002272785.1 CDS dsrH NC_011353.1 4297664 4297951 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(4297664..4297951) Escherichia coli O157:H7 str. EC4115 6966709 YP_002272786.1 CDS tusC NC_011353.1 4297959 4298318 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(4297959..4298318) Escherichia coli O157:H7 str. EC4115 6970979 YP_002272787.1 CDS tusD NC_011353.1 4298318 4298704 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(4298318..4298704) Escherichia coli O157:H7 str. EC4115 6971582 YP_002272788.1 CDS ECH74115_4655 NC_011353.1 4298704 4299426 R identified by match to protein family HMM PF08348; hypothetical protein complement(4298704..4299426) Escherichia coli O157:H7 str. EC4115 6966890 YP_002272789.1 CDS fkpA NC_011353.1 4299593 4300405 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(4299593..4300405) Escherichia coli O157:H7 str. EC4115 6967467 YP_002272790.1 CDS ECH74115_4657 NC_011353.1 4300626 4300844 D identified by match to protein family HMM PF04102; hypothetical protein 4300626..4300844 Escherichia coli O157:H7 str. EC4115 6968408 YP_002272791.1 CDS slyD NC_011353.1 4300893 4301483 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(4300893..4301483) Escherichia coli O157:H7 str. EC4115 6969360 YP_002272792.1 CDS ECH74115_4659 NC_011353.1 4301578 4301778 R identified by match to protein family HMM PF09526; match to protein family HMM TIGR02443; hypothetical protein complement(4301578..4301778) Escherichia coli O157:H7 str. EC4115 6969958 YP_002272793.1 CDS kefG NC_011353.1 4303593 4304147 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(4303593..4304147) Escherichia coli O157:H7 str. EC4115 6970130 YP_002272794.1 CDS ECH74115_4662 NC_011353.1 4304275 4306188 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 4304275..4306188 Escherichia coli O157:H7 str. EC4115 6968336 YP_002272795.1 CDS ECH74115_4663 NC_011353.1 4306188 4307210 D identified by match to protein family HMM PF00561; hydrolase 4306188..4307210 Escherichia coli O157:H7 str. EC4115 6969646 YP_002272796.1 CDS ECH74115_4664 NC_011353.1 4307204 4307422 D identified by match to protein family HMM PF06794; hypothetical protein 4307204..4307422 Escherichia coli O157:H7 str. EC4115 6971537 YP_002272797.1 CDS ECH74115_4665 NC_011353.1 4307476 4308345 D identified by match to protein family HMM PF00485; phosphoribulokinase/uridine kinase family protein 4307476..4308345 Escherichia coli O157:H7 str. EC4115 6970897 YP_002272798.1 CDS ECH74115_4666 NC_011353.1 4308400 4308804 R identified by match to protein family HMM PF02566; hypothetical protein complement(4308400..4308804) Escherichia coli O157:H7 str. EC4115 6967433 YP_002272799.1 CDS crp NC_011353.1 4309106 4309738 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 4309106..4309738 Escherichia coli O157:H7 str. EC4115 6967158 YP_002272800.1 CDS ECH74115_4668 NC_011353.1 4309789 4311879 D identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667; YccS/YhfK family integral membrane protein 4309789..4311879 Escherichia coli O157:H7 str. EC4115 6969052 YP_002272801.1 CDS argD NC_011353.1 4311946 4313166 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase complement(4311946..4313166) Escherichia coli O157:H7 str. EC4115 6968431 YP_002272802.1 CDS pabA NC_011353.1 4313252 4313815 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(4313252..4313815) Escherichia coli O157:H7 str. EC4115 6967742 YP_002272803.1 CDS fic NC_011353.1 4313847 4314449 R identified by match to protein family HMM PF02661; cell filamentation protein Fic complement(4313847..4314449) Escherichia coli O157:H7 str. EC4115 6966941 YP_002272804.1 CDS ECH74115_4672 NC_011353.1 4314439 4314606 R hypothetical protein complement(4314439..4314606) Escherichia coli O157:H7 str. EC4115 6969338 YP_002272805.1 CDS ppiA NC_011353.1 4314711 4315283 R identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase A complement(4314711..4315283) Escherichia coli O157:H7 str. EC4115 6968157 YP_002272806.1 CDS ECH74115_4674 NC_011353.1 4315427 4315573 R identified by glimmer; hypothetical protein complement(4315427..4315573) Escherichia coli O157:H7 str. EC4115 6971284 YP_002272807.1 CDS tsgA NC_011353.1 4315554 4316735 D identified by match to protein family HMM PF07690; hypothetical protein 4315554..4316735 Escherichia coli O157:H7 str. EC4115 6970550 YP_002272808.1 CDS nirB NC_011353.1 4316997 4319540 D identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; nitrite reductase [NAD(P)H], large subunit 4316997..4319540 Escherichia coli O157:H7 str. EC4115 6967204 YP_002272809.1 CDS nirD NC_011353.1 4319537 4319863 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 4319537..4319863 Escherichia coli O157:H7 str. EC4115 6972134 YP_002272810.1 CDS nirC NC_011353.1 4319989 4320795 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 4319989..4320795 Escherichia coli O157:H7 str. EC4115 6968296 YP_002272811.1 CDS cysG NC_011353.1 4320814 4322187 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 4320814..4322187 Escherichia coli O157:H7 str. EC4115 6967315 YP_002272812.1 CDS ECH74115_4680 NC_011353.1 4322442 4322609 D lipoprotein 4322442..4322609 Escherichia coli O157:H7 str. EC4115 6968134 YP_002272813.1 CDS ECH74115_4681 NC_011353.1 4322628 4322759 R identified by glimmer; hypothetical protein complement(4322628..4322759) Escherichia coli O157:H7 str. EC4115 6967333 YP_002272814.1 CDS frlA NC_011353.1 4322905 4324242 D inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; fructoselysine transporter 4322905..4324242 Escherichia coli O157:H7 str. EC4115 6970474 YP_002272815.1 CDS frlB NC_011353.1 4324263 4325285 D catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 4324263..4325285 Escherichia coli O157:H7 str. EC4115 6967540 YP_002272816.1 CDS ECH74115_4684 NC_011353.1 4325336 4326163 D YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 4325336..4326163 Escherichia coli O157:H7 str. EC4115 6967639 YP_002272817.1 CDS frlR NC_011353.1 4326982 4327779 D may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 4326982..4327779 Escherichia coli O157:H7 str. EC4115 6969402 YP_002272818.1 CDS trpS NC_011353.1 4327910 4328914 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(4327910..4328914) Escherichia coli O157:H7 str. EC4115 6970200 YP_002272819.1 CDS gph NC_011353.1 4328907 4329665 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(4328907..4329665) Escherichia coli O157:H7 str. EC4115 6968277 YP_002272820.1 CDS rpe NC_011353.1 4329658 4330335 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(4329658..4330335) Escherichia coli O157:H7 str. EC4115 6968857 YP_002272821.1 CDS dam NC_011353.1 4330353 4331189 R identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571; DNA adenine methylase complement(4330353..4331189) Escherichia coli O157:H7 str. EC4115 6968216 YP_002272822.1 CDS damX NC_011353.1 4331296 4332582 R identified by match to protein family HMM PF05036; hypothetical protein complement(4331296..4332582) Escherichia coli O157:H7 str. EC4115 6967244 YP_002272823.1 CDS aroB NC_011353.1 4332674 4333762 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(4332674..4333762) Escherichia coli O157:H7 str. EC4115 6970356 YP_002272824.1 CDS aroK NC_011353.1 4333819 4334496 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(4333819..4334496) Escherichia coli O157:H7 str. EC4115 6968438 YP_002272825.1 CDS hofQ NC_011353.1 4334741 4335979 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(4334741..4335979) Escherichia coli O157:H7 str. EC4115 6969088 YP_002272826.1 CDS ECH74115_4696 NC_011353.1 4335891 4336295 R hypothetical protein complement(4335891..4336295) Escherichia coli O157:H7 str. EC4115 6972028 YP_002272827.1 CDS ECH74115_4697 NC_011353.1 4336285 4336431 R hypothetical protein complement(4336285..4336431) Escherichia coli O157:H7 str. EC4115 6967114 YP_002272828.1 CDS ECH74115_4698 NC_011353.1 4336453 4336587 D identified by glimmer; hypothetical protein 4336453..4336587 Escherichia coli O157:H7 str. EC4115 6970743 YP_002272829.1 CDS ECH74115_4699 NC_011353.1 4336709 4337248 R identified by match to protein family HMM PF05137; PilN family protein complement(4336709..4337248) Escherichia coli O157:H7 str. EC4115 6971527 YP_002272830.1 CDS mrcA NC_011353.1 4338146 4340698 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 4338146..4340698 Escherichia coli O157:H7 str. EC4115 6971106 YP_002272831.1 CDS nudE NC_011353.1 4340863 4341423 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(4340863..4341423) Escherichia coli O157:H7 str. EC4115 6969195 YP_002272832.1 CDS ECH74115_4703 NC_011353.1 4341743 4343878 D identified by match to protein family HMM PF07095; hypothetical protein 4341743..4343878 Escherichia coli O157:H7 str. EC4115 6970568 YP_002272833.1 CDS ECH74115_4704 NC_011353.1 4343943 4344611 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD hydrolase, IA family 4343943..4344611 Escherichia coli O157:H7 str. EC4115 6971420 YP_002272834.1 CDS hslR NC_011353.1 4344622 4345023 D identified by match to protein family HMM PF01479; ribosome-associated heat shock protein Hsp15 4344622..4345023 Escherichia coli O157:H7 str. EC4115 6972165 YP_002272835.1 CDS hslO NC_011353.1 4345042 4345926 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 4345042..4345926 Escherichia coli O157:H7 str. EC4115 6968724 YP_002272836.1 CDS ECH74115_4707 NC_011353.1 4345989 4347713 R hypothetical protein complement(4345989..4347713) Escherichia coli O157:H7 str. EC4115 6967047 YP_002272837.1 CDS ECH74115_4708 NC_011353.1 4347719 4347847 R identified by glimmer; hypothetical protein complement(4347719..4347847) Escherichia coli O157:H7 str. EC4115 6970172 YP_002272838.1 CDS pckA NC_011353.1 4348092 4349714 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 4348092..4349714 Escherichia coli O157:H7 str. EC4115 6968247 YP_002272839.1 CDS envZ NC_011353.1 4349790 4351142 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(4349790..4351142) Escherichia coli O157:H7 str. EC4115 6970484 YP_002272840.1 CDS ompR NC_011353.1 4351139 4351858 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(4351139..4351858) Escherichia coli O157:H7 str. EC4115 6968395 YP_002272841.1 CDS greB NC_011353.1 4352086 4352562 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 4352086..4352562 Escherichia coli O157:H7 str. EC4115 6971704 YP_002272842.1 CDS ECH74115_4713 NC_011353.1 4352659 4354980 D identified by match to protein family HMM PF00575; match to protein family HMM PF09371; transcriptional accessory protein 4352659..4354980 Escherichia coli O157:H7 str. EC4115 6971666 YP_002272843.1 CDS ECH74115_4714 NC_011353.1 4355045 4355164 D hypothetical protein 4355045..4355164 Escherichia coli O157:H7 str. EC4115 6969602 YP_002272844.1 CDS feoA NC_011353.1 4355418 4355645 D identified by match to protein family HMM PF04023; ferrous iron transport protein A 4355418..4355645 Escherichia coli O157:H7 str. EC4115 6970445 YP_002272845.1 CDS feoB NC_011353.1 4355662 4357983 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 4355662..4357983 Escherichia coli O157:H7 str. EC4115 6968319 YP_002272846.1 CDS ECH74115_4717 NC_011353.1 4357983 4358219 D identified by match to protein family HMM PF09012; hypothetical protein 4357983..4358219 Escherichia coli O157:H7 str. EC4115 6968205 YP_002272847.1 CDS ECH74115_4718 NC_011353.1 4358422 4359300 D identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 4358422..4359300 Escherichia coli O157:H7 str. EC4115 6967083 YP_002272848.1 CDS ECH74115_4719 NC_011353.1 4359327 4360097 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(4359327..4360097) Escherichia coli O157:H7 str. EC4115 6967672 YP_002272849.1 CDS gntX NC_011353.1 4360072 4360818 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 4360072..4360818 Escherichia coli O157:H7 str. EC4115 6969245 YP_002272850.1 CDS gntY NC_011353.1 4360877 4361452 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 4360877..4361452 Escherichia coli O157:H7 str. EC4115 6967049 YP_002272851.1 CDS gntT NC_011353.1 4361813 4363129 D identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; high-affinity gluconate transporter 4361813..4363129 Escherichia coli O157:H7 str. EC4115 6967347 YP_002272852.1 CDS malQ NC_011353.1 4363174 4365258 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(4363174..4365258) Escherichia coli O157:H7 str. EC4115 6969071 YP_002272853.1 CDS malP NC_011353.1 4365268 4367661 R identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; maltodextrin phosphorylase complement(4365268..4367661) Escherichia coli O157:H7 str. EC4115 6968435 YP_002272854.1 CDS malT NC_011353.1 4368273 4370978 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 4368273..4370978 Escherichia coli O157:H7 str. EC4115 6968490 YP_002272855.1 CDS ECH74115_4726 NC_011353.1 4371045 4371323 D identified by match to protein family HMM PF08681; hypothetical protein 4371045..4371323 Escherichia coli O157:H7 str. EC4115 6967410 YP_002272856.1 CDS ECH74115_4727 NC_011353.1 4371314 4371799 D identified by match to protein family HMM PF00583; GNAT family acetyltransferase 4371314..4371799 Escherichia coli O157:H7 str. EC4115 6971104 YP_002272857.1 CDS rtcA NC_011353.1 4371849 4372877 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(4371849..4372877) Escherichia coli O157:H7 str. EC4115 6971165 YP_002272858.1 CDS rtcB NC_011353.1 4372881 4374107 R identified by match to protein family HMM PF01139; RtcB protein complement(4372881..4374107) Escherichia coli O157:H7 str. EC4115 6970370 YP_002272859.1 CDS rtcR NC_011353.1 4374295 4375893 D identified by match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728; sigma-54 dependent transcriptional regulator RtcR 4374295..4375893 Escherichia coli O157:H7 str. EC4115 6968754 YP_002272860.1 CDS glpR NC_011353.1 4375875 4376633 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(4375875..4376633) Escherichia coli O157:H7 str. EC4115 6970757 YP_002272861.1 CDS ECH74115_4732 NC_011353.1 4376650 4377480 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(4376650..4377480) Escherichia coli O157:H7 str. EC4115 6969951 YP_002272862.1 CDS glpE NC_011353.1 4377525 4377851 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(4377525..4377851) Escherichia coli O157:H7 str. EC4115 6968669 YP_002272863.1 CDS glpD NC_011353.1 4378041 4379546 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 4378041..4379546 Escherichia coli O157:H7 str. EC4115 6968221 YP_002272864.1 CDS ECH74115_4735 NC_011353.1 4379593 4379739 D hypothetical protein 4379593..4379739 Escherichia coli O157:H7 str. EC4115 6970289 YP_002272865.1 CDS ECH74115_4736 NC_011353.1 4379761 4380363 R hypothetical protein complement(4379761..4380363) Escherichia coli O157:H7 str. EC4115 6970571 YP_002272866.1 CDS ECH74115_4737 NC_011353.1 4380363 4381355 R hypothetical protein complement(4380363..4381355) Escherichia coli O157:H7 str. EC4115 6969749 YP_002272867.1 CDS ECH74115_4738 NC_011353.1 4381381 4382796 R hypothetical protein complement(4381381..4382796) Escherichia coli O157:H7 str. EC4115 6972170 YP_002272868.1 CDS ECH74115_4739 NC_011353.1 4382795 4382911 D identified by glimmer; hypothetical protein 4382795..4382911 Escherichia coli O157:H7 str. EC4115 6971389 YP_002272869.1 CDS glgP NC_011353.1 4383014 4385461 R identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase complement(4383014..4385461) Escherichia coli O157:H7 str. EC4115 6970672 YP_002272870.1 CDS glgA NC_011353.1 4385480 4386913 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(4385480..4386913) Escherichia coli O157:H7 str. EC4115 6970040 YP_002272871.1 CDS glgC NC_011353.1 4386913 4388208 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(4386913..4388208) Escherichia coli O157:H7 str. EC4115 6971928 YP_002272872.1 CDS glgX NC_011353.1 4388226 4390199 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(4388226..4390199) Escherichia coli O157:H7 str. EC4115 6969241 YP_002272873.1 CDS glgB NC_011353.1 4390196 4392382 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(4390196..4392382) Escherichia coli O157:H7 str. EC4115 6968699 YP_002272874.1 CDS asd NC_011353.1 4392655 4393758 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(4392655..4393758) Escherichia coli O157:H7 str. EC4115 6968050 YP_002272875.1 CDS ECH74115_4746 NC_011353.1 4393950 4394543 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4393950..4394543 Escherichia coli O157:H7 str. EC4115 6966619 YP_002272876.1 CDS ECH74115_4747 NC_011353.1 4394589 4395791 R DNA protecting protein DprA complement(4394589..4395791) Escherichia coli O157:H7 str. EC4115 6971876 YP_002272877.1 CDS gntU NC_011353.1 4398055 4399395 R identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; low affinity gluconate transporter complement(4398055..4399395) Escherichia coli O157:H7 str. EC4115 6968304 YP_002272878.1 CDS gntK NC_011353.1 4399399 4399947 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(4399399..4399947) Escherichia coli O157:H7 str. EC4115 6968106 YP_002272879.1 CDS gntR NC_011353.1 4400065 4401060 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator GntR complement(4400065..4401060) Escherichia coli O157:H7 str. EC4115 6967823 YP_002272880.1 CDS ECH74115_4756 NC_011353.1 4401138 4401287 D identified by glimmer; hypothetical protein 4401138..4401287 Escherichia coli O157:H7 str. EC4115 6966876 YP_002272881.1 CDS ECH74115_4755 NC_011353.1 4401284 4401979 R identified by match to protein family HMM PF02678; match to protein family HMM PF07883; pirin family protein complement(4401284..4401979) Escherichia coli O157:H7 str. EC4115 6971921 YP_002272882.1 CDS ECH74115_4757 NC_011353.1 4402102 4403139 R identified by match to protein family HMM PF01408; match to protein family HMM PF02894; dehydrogenase complement(4402102..4403139) Escherichia coli O157:H7 str. EC4115 6971599 YP_002272883.1 CDS ECH74115_4759 NC_011353.1 4403473 4403961 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 4403473..4403961 Escherichia coli O157:H7 str. EC4115 6972319 YP_002272884.1 CDS ECH74115_4760 NC_011353.1 4404172 4405083 D hypothetical protein 4404172..4405083 Escherichia coli O157:H7 str. EC4115 6970716 YP_002272885.1 CDS ggt NC_011353.1 4405817 4407562 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(4405817..4407562) Escherichia coli O157:H7 str. EC4115 6970078 YP_002272886.1 CDS ECH74115_4763 NC_011353.1 4407682 4408122 D hypothetical protein 4407682..4408122 Escherichia coli O157:H7 str. EC4115 6968918 YP_002272887.1 CDS ugpQ NC_011353.1 4408109 4408852 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(4408109..4408852) Escherichia coli O157:H7 str. EC4115 6968064 YP_002272888.1 CDS ugpC NC_011353.1 4408849 4409919 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(4408849..4409919) Escherichia coli O157:H7 str. EC4115 6968129 YP_002272889.1 CDS ECH74115_4765 NC_011353.1 4409921 4410766 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(4409921..4410766) Escherichia coli O157:H7 str. EC4115 6970645 YP_002272890.1 CDS ugpA NC_011353.1 4410763 4411650 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(4410763..4411650) Escherichia coli O157:H7 str. EC4115 6970135 YP_002272891.1 CDS ugpB NC_011353.1 4411748 4413064 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(4411748..4413064) Escherichia coli O157:H7 str. EC4115 6969519 YP_002272892.1 CDS ECH74115_4768 NC_011353.1 4413275 4413427 R identified by glimmer; hypothetical protein complement(4413275..4413427) Escherichia coli O157:H7 str. EC4115 6971347 YP_002272893.1 CDS ECH74115_4769 NC_011353.1 4413424 4414170 R hypothetical protein complement(4413424..4414170) Escherichia coli O157:H7 str. EC4115 6971105 YP_002272894.1 CDS ECH74115_4771 NC_011353.1 4414187 4414300 D identified by glimmer; hypothetical protein 4414187..4414300 Escherichia coli O157:H7 str. EC4115 6967921 YP_002272895.1 CDS livF NC_011353.1 4414289 4415002 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4414289..4415002) Escherichia coli O157:H7 str. EC4115 6969059 YP_002272896.1 CDS livG NC_011353.1 4415004 4415771 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4415004..4415771) Escherichia coli O157:H7 str. EC4115 6967325 YP_002272897.1 CDS livM NC_011353.1 4415768 4417045 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(4415768..4417045) Escherichia coli O157:H7 str. EC4115 6968394 YP_002272898.1 CDS livH NC_011353.1 4417042 4417968 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(4417042..4417968) Escherichia coli O157:H7 str. EC4115 6966926 YP_002272899.1 CDS livK NC_011353.1 4418016 4419125 R identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK complement(4418016..4419125) Escherichia coli O157:H7 str. EC4115 6971838 YP_002272900.1 CDS ECH74115_4776 NC_011353.1 4419277 4419414 R identified by glimmer; hypothetical protein complement(4419277..4419414) Escherichia coli O157:H7 str. EC4115 6968660 YP_002272901.1 CDS ECH74115_4778 NC_011353.1 4419549 4419932 D identified by match to protein family HMM PF00583; GNAT family acetyltransferase 4419549..4419932 Escherichia coli O157:H7 str. EC4115 6967845 YP_002272902.1 CDS ECH74115_4777 NC_011353.1 4419929 4420456 R hypothetical protein complement(4419929..4420456) Escherichia coli O157:H7 str. EC4115 6969296 YP_002272903.1 CDS ECH74115_4779 NC_011353.1 4420463 4420729 R identified by match to protein family HMM PF08681; hypothetical protein complement(4420463..4420729) Escherichia coli O157:H7 str. EC4115 6970144 YP_002272904.1 CDS livJ NC_011353.1 4420879 4421982 R identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic Leu/Ile/Val-binding protein LivJ complement(4420879..4421982) Escherichia coli O157:H7 str. EC4115 6971869 YP_002272905.1 CDS rpoH NC_011353.1 4422253 4423107 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(4422253..4423107) Escherichia coli O157:H7 str. EC4115 6970923 YP_002272906.1 CDS ftsX NC_011353.1 4423352 4424410 R ABC transporter membrane protein; cell division protein FtsX complement(4423352..4424410) Escherichia coli O157:H7 str. EC4115 6969144 YP_002272907.1 CDS ftsE NC_011353.1 4424403 4425071 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(4424403..4425071) Escherichia coli O157:H7 str. EC4115 6968308 YP_002272908.1 CDS ftsY NC_011353.1 4425074 4426570 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(4425074..4426570) Escherichia coli O157:H7 str. EC4115 6970145 YP_002272909.1 CDS rsmD NC_011353.1 4426720 4427316 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4426720..4427316 Escherichia coli O157:H7 str. EC4115 6969411 YP_002272910.1 CDS ECH74115_4786 NC_011353.1 4427306 4427575 D identified by match to protein family HMM PF06611; hypothetical protein 4427306..4427575 Escherichia coli O157:H7 str. EC4115 6969118 YP_002272911.1 CDS ECH74115_4787 NC_011353.1 4427578 4427937 R hypothetical protein complement(4427578..4427937) Escherichia coli O157:H7 str. EC4115 6968531 YP_002272912.1 CDS ECH74115_4788 NC_011353.1 4428078 4428704 D identified by match to protein family HMM PF07947; hypothetical protein 4428078..4428704 Escherichia coli O157:H7 str. EC4115 6966913 YP_002272913.1 CDS zntA NC_011353.1 4428778 4430976 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4428778..4430976 Escherichia coli O157:H7 str. EC4115 6969186 YP_002272914.1 CDS tusA NC_011353.1 4431078 4431323 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(4431078..4431323) Escherichia coli O157:H7 str. EC4115 6971757 YP_002272915.1 CDS ECH74115_4791 NC_011353.1 4431544 4432209 D identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 4431544..4432209 Escherichia coli O157:H7 str. EC4115 6971158 YP_002272916.1 CDS ECH74115_4792 NC_011353.1 4432282 4432839 D hypothetical protein 4432282..4432839 Escherichia coli O157:H7 str. EC4115 6969503 YP_002272917.1 CDS ECH74115_4793 NC_011353.1 4432843 4434093 R identified by match to protein family HMM PF07690; major facilitator superfamily transporter complement(4432843..4434093) Escherichia coli O157:H7 str. EC4115 6971648 YP_002272918.1 CDS ECH74115_4794 NC_011353.1 4434192 4435241 D identified by match to protein family HMM PF01594; inner membrane protein YhhT 4434192..4435241 Escherichia coli O157:H7 str. EC4115 6970249 YP_002272919.1 CDS ECH74115_4795 NC_011353.1 4435633 4436010 D hypothetical protein 4435633..4436010 Escherichia coli O157:H7 str. EC4115 6969430 YP_002272920.1 CDS ECH74115_4796 NC_011353.1 4436079 4437137 D identified by match to protein family HMM PF00891; match to protein family HMM PF08242; O-methyltransferase, family 2 4436079..4437137 Escherichia coli O157:H7 str. EC4115 6971615 YP_002272921.1 CDS ECH74115_4797 NC_011353.1 4437178 4437900 D beta-ketoacyl synthase domain-containing protein 4437178..4437900 Escherichia coli O157:H7 str. EC4115 6971177 YP_002272922.1 CDS ECH74115_4800 NC_011353.1 4438693 4438950 D acyl carrier protein 4438693..4438950 Escherichia coli O157:H7 str. EC4115 6969141 YP_002272923.1 CDS ECH74115_4801 NC_011353.1 4438962 4439213 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 4438962..4439213 Escherichia coli O157:H7 str. EC4115 6968517 YP_002272924.1 CDS ECH74115_4802 NC_011353.1 4439218 4439799 D DNA gyrase subunit B 4439218..4439799 Escherichia coli O157:H7 str. EC4115 6970205 YP_002272925.1 CDS ECH74115_4805 NC_011353.1 4441144 4441497 D (3R)-hydroxymyristoyl-ACP dehydratase 4441144..4441497 Escherichia coli O157:H7 str. EC4115 6970825 YP_002272926.1 CDS ECH74115_4806 NC_011353.1 4441488 4443164 D identified by match to protein family HMM PF00535; family 2 glycosyl transferase 4441488..4443164 Escherichia coli O157:H7 str. EC4115 6971643 YP_002272927.1 CDS ECH74115_4807 NC_011353.1 4443168 4443590 D identified by match to protein family HMM PF03061; thioesterase superfamily protein 4443168..4443590 Escherichia coli O157:H7 str. EC4115 6969563 YP_002272928.1 CDS ECH74115_4808 NC_011353.1 4443587 4444192 D identified by match to protein family HMM PF03548; outer membrane lipoprotein carrier protein LolA 4443587..4444192 Escherichia coli O157:H7 str. EC4115 6972041 YP_002272929.1 CDS ECH74115_4809 NC_011353.1 4444161 4446479 D hypothetical protein 4444161..4446479 Escherichia coli O157:H7 str. EC4115 6971264 YP_002272930.1 CDS ECH74115_4810 NC_011353.1 4446476 4447060 D hypothetical protein 4446476..4447060 Escherichia coli O157:H7 str. EC4115 6967567 YP_002272931.1 CDS ECH74115_4811 NC_011353.1 4447062 4448231 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 4447062..4448231 Escherichia coli O157:H7 str. EC4115 6966888 YP_002272932.1 CDS ECH74115_4812 NC_011353.1 4448228 4448692 D identified by match to protein family HMM PF07977; FabA-like domain-containing protein 4448228..4448692 Escherichia coli O157:H7 str. EC4115 6966659 YP_002272933.1 CDS fabG NC_011353.1 4448692 4449423 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4448692..4449423 Escherichia coli O157:H7 str. EC4115 6968889 YP_002272934.1 CDS ECH74115_4814 NC_011353.1 4449420 4450649 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 4449420..4450649 Escherichia coli O157:H7 str. EC4115 6968866 YP_002272935.1 CDS acpT NC_011353.1 4450651 4451238 D identified by match to protein family HMM PF01648; holo-(acyl carrier protein) synthase 2 4450651..4451238 Escherichia coli O157:H7 str. EC4115 6966706 YP_002272936.1 CDS nikA NC_011353.1 4451349 4452923 D identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294; nickel ABC transporter periplasmic nickel-binding protein NikA 4451349..4452923 Escherichia coli O157:H7 str. EC4115 6967632 YP_002272937.1 CDS nikB NC_011353.1 4452923 4453867 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4452923..4453867 Escherichia coli O157:H7 str. EC4115 6971103 YP_002272938.1 CDS nikC NC_011353.1 4453864 4454697 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4453864..4454697 Escherichia coli O157:H7 str. EC4115 6971308 YP_002272939.1 CDS nikD NC_011353.1 4454697 4455461 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4454697..4455461 Escherichia coli O157:H7 str. EC4115 6971934 YP_002272940.1 CDS nikE NC_011353.1 4455458 4456264 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4455458..4456264 Escherichia coli O157:H7 str. EC4115 6970175 YP_002272941.1 CDS nikR NC_011353.1 4456270 4456671 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4456270..4456671 Escherichia coli O157:H7 str. EC4115 6970646 YP_002272942.1 CDS ECH74115_4822 NC_011353.1 4456870 4457616 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4456870..4457616 Escherichia coli O157:H7 str. EC4115 6968808 YP_002272943.1 CDS ECH74115_4823 NC_011353.1 4457641 4458114 D identified by match to protein family HMM PF00359; PTS system sugar transporter subunit IIA 4457641..4458114 Escherichia coli O157:H7 str. EC4115 6968029 YP_002272944.1 CDS ECH74115_4824 NC_011353.1 4458111 4458392 D identified by match to protein family HMM PF02302; PTS system sugar transporter subunit IIB 4458111..4458392 Escherichia coli O157:H7 str. EC4115 6969845 YP_002272945.1 CDS ECH74115_4825 NC_011353.1 4458469 4459827 D identified by match to protein family HMM PF03611; PTS system sugar transporter subunit IIC 4458469..4459827 Escherichia coli O157:H7 str. EC4115 6970663 YP_002272946.1 CDS ECH74115_4826 NC_011353.1 4459820 4461328 D identified by match to protein family HMM PF00370; match to protein family HMM PF02782; FGGY family carbohydrate kinase 4459820..4461328 Escherichia coli O157:H7 str. EC4115 6968182 YP_002272947.1 CDS ECH74115_4827 NC_011353.1 4461318 4461587 D identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; HPr family phosphocarrier protein 4461318..4461587 Escherichia coli O157:H7 str. EC4115 6969027 YP_002272948.1 CDS gatY NC_011353.1 4461619 4462479 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 4461619..4462479 Escherichia coli O157:H7 str. EC4115 6967923 YP_002272949.1 CDS ECH74115_4829 NC_011353.1 4462529 4462888 R identified by match to protein family HMM PF05534; HicB family protein complement(4462529..4462888) Escherichia coli O157:H7 str. EC4115 6967199 YP_002272950.1 CDS ECH74115_4830 NC_011353.1 4463233 4464357 R identified by match to protein family HMM PF01061; ABC transporter ATP-binding protein complement(4463233..4464357) Escherichia coli O157:H7 str. EC4115 6970878 YP_002272951.1 CDS ECH74115_4831 NC_011353.1 4464357 4467092 R identified by match to protein family HMM PF00005; match to protein family HMM PF01061; ABC transporter ATP-binding protein complement(4464357..4467092) Escherichia coli O157:H7 str. EC4115 6967457 YP_002272952.1 CDS ECH74115_4832 NC_011353.1 4467089 4468156 R identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family complement(4467089..4468156) Escherichia coli O157:H7 str. EC4115 6969693 YP_002272953.1 CDS ECH74115_4833 NC_011353.1 4468149 4468280 R hypothetical protein complement(4468149..4468280) Escherichia coli O157:H7 str. EC4115 6971961 YP_002272954.1 CDS ECH74115_4834 NC_011353.1 4468522 4470144 R hypothetical protein complement(4468522..4470144) Escherichia coli O157:H7 str. EC4115 6969415 YP_002272955.1 CDS ECH74115_4835 NC_011353.1 4470406 4472016 R hypothetical protein complement(4470406..4472016) Escherichia coli O157:H7 str. EC4115 6970323 YP_002272956.1 CDS ECH74115_4836 NC_011353.1 4472400 4473452 D hypothetical protein 4472400..4473452 Escherichia coli O157:H7 str. EC4115 6971143 YP_002272957.1 CDS ECH74115_4838 NC_011353.1 4473770 4474972 R identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; pyridine nucleotide-disulfide oxidoreductase family protein complement(4473770..4474972) Escherichia coli O157:H7 str. EC4115 6967009 YP_002272958.1 CDS pitA NC_011353.1 4475204 4476703 D identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 1 4475204..4476703 Escherichia coli O157:H7 str. EC4115 6967768 YP_002272959.1 CDS uspB NC_011353.1 4476774 4477055 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(4476774..4477055) Escherichia coli O157:H7 str. EC4115 6968927 YP_002272960.1 CDS uspA NC_011353.1 4477500 4477934 D identified by match to protein family HMM PF00582; universal stress protein A 4477500..4477934 Escherichia coli O157:H7 str. EC4115 6969552 YP_002272961.1 CDS ECH74115_4842 NC_011353.1 4478117 4478296 R hypothetical protein complement(4478117..4478296) Escherichia coli O157:H7 str. EC4115 6969550 YP_002272962.1 CDS ECH74115_4843 NC_011353.1 4478251 4479720 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4478251..4479720 Escherichia coli O157:H7 str. EC4115 6968930 YP_002272963.1 CDS ECH74115_4844 NC_011353.1 4479769 4480521 R predicted SAM-dependent methyltransferase; methyltransferase complement(4479769..4480521) Escherichia coli O157:H7 str. EC4115 6968695 YP_002272964.1 CDS prlC NC_011353.1 4480529 4482571 R identified by match to protein family HMM PF01432; oligopeptidase A complement(4480529..4482571) Escherichia coli O157:H7 str. EC4115 6968071 YP_002272965.1 CDS yhiR NC_011353.1 4482774 4483616 D identified by match to protein family HMM PF04378; DNA utilization protein YhiR 4482774..4483616 Escherichia coli O157:H7 str. EC4115 6967562 YP_002272966.1 CDS gor NC_011353.1 4483688 4485040 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4483688..4485040 Escherichia coli O157:H7 str. EC4115 6966879 YP_002272967.1 CDS ECH74115_4848 NC_011353.1 4485094 4485210 R identified by glimmer; hypothetical protein complement(4485094..4485210) Escherichia coli O157:H7 str. EC4115 6968001 YP_002272968.1 CDS ECH74115_4849 NC_011353.1 4485205 4485378 D identified by glimmer; hypothetical protein 4485205..4485378 Escherichia coli O157:H7 str. EC4115 6967911 YP_002272969.1 CDS arsR NC_011353.1 4485921 4486274 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 4485921..4486274 Escherichia coli O157:H7 str. EC4115 6966831 YP_002272970.1 CDS arsB NC_011353.1 4486328 4487617 D identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935; arsenical pump membrane protein 4486328..4487617 Escherichia coli O157:H7 str. EC4115 6971727 YP_002272971.1 CDS arsC2 NC_011353.1 4487630 4488055 D identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 4487630..4488055 Escherichia coli O157:H7 str. EC4115 6972059 YP_002272972.1 CDS ECH74115_4854 NC_011353.1 4490151 4490717 D identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752; outer membrane lipoprotein, Slp family 4490151..4490717 Escherichia coli O157:H7 str. EC4115 6970821 YP_002272973.1 CDS dctR NC_011353.1 4490873 4491403 D identified by match to protein family HMM PF00196; transcriptional regulator DctR 4490873..4491403 Escherichia coli O157:H7 str. EC4115 6971697 YP_002272974.1 CDS hmuS NC_011353.1 4491464 4492492 R identified by match to protein family HMM PF05171; hemin transport protein HmuS complement(4491464..4492492) Escherichia coli O157:H7 str. EC4115 6967086 YP_002272975.1 CDS chuA NC_011353.1 4492541 4494523 R identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01785; match to protein family HMM TIGR01786; outer membrane heme/hemoglobin receptor ChuA complement(4492541..4494523) Escherichia coli O157:H7 str. EC4115 6967853 YP_002272976.1 CDS ECH74115_4858 NC_011353.1 4494462 4494605 D hypothetical protein 4494462..4494605 Escherichia coli O157:H7 str. EC4115 6967482 YP_002272977.1 CDS ECH74115_4860 NC_011353.1 4494799 4495005 R hypothetical protein complement(4494799..4495005) Escherichia coli O157:H7 str. EC4115 6969808 YP_002272978.1 CDS ECH74115_4861 NC_011353.1 4495266 4496120 D identified by match to protein family HMM PF01497; periplasmic-binding protein 4495266..4496120 Escherichia coli O157:H7 str. EC4115 6969730 YP_002272979.1 CDS ECH74115_4862 NC_011353.1 4496140 4497477 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4496140..4497477 Escherichia coli O157:H7 str. EC4115 6967461 YP_002272980.1 CDS ECH74115_4863 NC_011353.1 4497490 4497984 D identified by match to protein family HMM PF06228; hypothetical protein 4497490..4497984 Escherichia coli O157:H7 str. EC4115 6966827 YP_002272981.1 CDS ECH74115_4864 NC_011353.1 4497984 4498607 D hypothetical protein 4497984..4498607 Escherichia coli O157:H7 str. EC4115 6968424 YP_002272982.1 CDS ECH74115_4865 NC_011353.1 4498692 4499648 D identified by match to protein family HMM PF01032; ABC transporter iron chelate uptake transporter (FeCT) family, permease 4498692..4499648 Escherichia coli O157:H7 str. EC4115 6967686 YP_002272983.1 CDS hmuV NC_011353.1 4499645 4500415 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4499645..4500415 Escherichia coli O157:H7 str. EC4115 6966971 YP_002272984.1 CDS ECH74115_4867 NC_011353.1 4500467 4501126 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(4500467..4501126) Escherichia coli O157:H7 str. EC4115 6972212 YP_002272985.1 CDS hdeB NC_011353.1 4501178 4501516 R acid-resistance protein complement(4501178..4501516) Escherichia coli O157:H7 str. EC4115 6969143 YP_002272986.1 CDS ECH74115_4869 NC_011353.1 4501620 4501952 R inactive form; acid-resistance protein complement(4501620..4501952) Escherichia coli O157:H7 str. EC4115 6968337 YP_002272987.1 CDS ECH74115_4870 NC_011353.1 4502207 4502779 D acid-resistance membrane protein 4502207..4502779 Escherichia coli O157:H7 str. EC4115 6967876 YP_002272988.1 CDS gadE NC_011353.1 4503578 4504105 D transcriptional regulator GadE 4503578..4504105 Escherichia coli O157:H7 str. EC4115 6967403 YP_002272989.1 CDS ECH74115_4872 NC_011353.1 4504422 4504514 R identified by glimmer; hypothetical protein complement(4504422..4504514) Escherichia coli O157:H7 str. EC4115 6971714 YP_002272990.1 CDS mdtE NC_011353.1 4504444 4505601 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4504444..4505601 Escherichia coli O157:H7 str. EC4115 6971171 YP_002272991.1 CDS mdtF NC_011353.1 4505626 4508739 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; multidrug resistance protein MdtF 4505626..4508739 Escherichia coli O157:H7 str. EC4115 6969567 YP_002272992.1 CDS gadW NC_011353.1 4509102 4509830 R identified by match to protein family HMM PF00165; transcriptional regulator GadW complement(4509102..4509830) Escherichia coli O157:H7 str. EC4115 6970174 YP_002272993.1 CDS gadX NC_011353.1 4510198 4511022 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(4510198..4511022) Escherichia coli O157:H7 str. EC4115 6972303 YP_002272994.1 CDS ECH74115_4878 NC_011353.1 4511107 4511277 R identified by glimmer; hypothetical protein complement(4511107..4511277) Escherichia coli O157:H7 str. EC4115 6969130 YP_002272995.1 CDS gadB NC_011353.1 4511393 4512793 R identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase GadB complement(4511393..4512793) Escherichia coli O157:H7 str. EC4115 6967105 YP_002272996.1 CDS ECH74115_4880 NC_011353.1 4513004 4514401 R identified by match to protein family HMM PF03150; di-heme cytochrome c peroxidase family protein complement(4513004..4514401) Escherichia coli O157:H7 str. EC4115 6967893 YP_002272997.1 CDS ECH74115_4881 NC_011353.1 4514582 4514701 D identified by glimmer; hypothetical protein 4514582..4514701 Escherichia coli O157:H7 str. EC4115 6968617 YP_002272998.1 CDS treF NC_011353.1 4514806 4516455 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4514806..4516455 Escherichia coli O157:H7 str. EC4115 6969247 YP_002272999.1 CDS ECH74115_4883 NC_011353.1 4516506 4517108 R identified by match to protein family HMM PF00196; match to protein family HMM PF08281; LuxR family transcriptional regulator complement(4516506..4517108) Escherichia coli O157:H7 str. EC4115 6967109 YP_002273000.1 CDS ECH74115_4884 NC_011353.1 4517556 4518527 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4517556..4518527 Escherichia coli O157:H7 str. EC4115 6967628 YP_002273001.1 CDS ECH74115_4885 NC_011353.1 4518576 4519589 D identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766; ribonuclease 4518576..4519589 Escherichia coli O157:H7 str. EC4115 6967222 YP_002273002.1 CDS ECH74115_4886 NC_011353.1 4520001 4521323 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; MFS transporter metabolite:H+ symporter (MHS) family protein 4520001..4521323 Escherichia coli O157:H7 str. EC4115 6967783 YP_002273003.1 CDS ECH74115_4887 NC_011353.1 4521505 4523565 R identified by match to protein family HMM PF05170; AsmA family protein complement(4521505..4523565) Escherichia coli O157:H7 str. EC4115 6971693 YP_002273004.1 CDS ECH74115_4888 NC_011353.1 4523635 4524270 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(4523635..4524270) Escherichia coli O157:H7 str. EC4115 6969518 YP_002273005.1 CDS ECH74115_4889 NC_011353.1 4524402 4524629 R identified by glimmer; hypothetical protein complement(4524402..4524629) Escherichia coli O157:H7 str. EC4115 6966922 YP_002273006.1 CDS kdgK NC_011353.1 4524634 4525563 D identified by match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase 4524634..4525563 Escherichia coli O157:H7 str. EC4115 6969127 YP_002273007.1 CDS ECH74115_4891 NC_011353.1 4525659 4527155 R identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 (pitrilysin) family complement(4525659..4527155) Escherichia coli O157:H7 str. EC4115 6971749 YP_002273008.1 CDS dctA NC_011353.1 4527376 4528662 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(4527376..4528662) Escherichia coli O157:H7 str. EC4115 6971169 YP_002273009.1 CDS ECH74115_4893 NC_011353.1 4528666 4528764 D identified by glimmer; hypothetical protein 4528666..4528764 Escherichia coli O157:H7 str. EC4115 6969557 YP_002273010.1 CDS ECH74115_4894 NC_011353.1 4528845 4530833 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase complement(4528845..4530833) Escherichia coli O157:H7 str. EC4115 6971803 YP_002273011.1 CDS ECH74115_4895 NC_011353.1 4530915 4534388 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(4530915..4534388) Escherichia coli O157:H7 str. EC4115 6971649 YP_002273012.1 CDS bcsZ NC_011353.1 4534370 4535482 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(4534370..4535482) Escherichia coli O157:H7 str. EC4115 6967104 YP_002273013.1 CDS bcsB NC_011353.1 4535483 4537858 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(4535483..4537858) Escherichia coli O157:H7 str. EC4115 6967134 YP_002273014.1 CDS bcsA NC_011353.1 4537869 4540487 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(4537869..4540487) Escherichia coli O157:H7 str. EC4115 6967926 YP_002273015.1 CDS ECH74115_4901 NC_011353.1 4541248 4541436 R hypothetical protein complement(4541248..4541436) Escherichia coli O157:H7 str. EC4115 6967058 YP_002273016.1 CDS ECH74115_4902 NC_011353.1 4541721 4543280 D identified by match to protein family HMM TIGR03369; hypothetical protein 4541721..4543280 Escherichia coli O157:H7 str. EC4115 6967675 YP_002273017.1 CDS bcsF NC_011353.1 4543277 4543468 D identified by match to protein family HMM TIGR03493; cellulose biosynthesis protein BcsF 4543277..4543468 Escherichia coli O157:H7 str. EC4115 6968653 YP_002273018.1 CDS ECH74115_4904 NC_011353.1 4543465 4545144 D identified by match to protein family HMM TIGR03368; hypothetical protein 4543465..4545144 Escherichia coli O157:H7 str. EC4115 6969223 YP_002273019.1 CDS ECH74115_4905 NC_011353.1 4545231 4545398 R hypothetical protein complement(4545231..4545398) Escherichia coli O157:H7 str. EC4115 6969591 YP_002273020.1 CDS ECH74115_4906 NC_011353.1 4545503 4545664 R identified by glimmer; hypothetical protein complement(4545503..4545664) Escherichia coli O157:H7 str. EC4115 6968764 YP_002273021.1 CDS ECH74115_4907 NC_011353.1 4545814 4547085 D identified by match to protein family HMM TIGR00814; serine transporter family protein 4545814..4547085 Escherichia coli O157:H7 str. EC4115 6967938 YP_002273022.1 CDS dppF NC_011353.1 4547115 4548119 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(4547115..4548119) Escherichia coli O157:H7 str. EC4115 6968605 YP_002273023.1 CDS dppD NC_011353.1 4548116 4549099 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(4548116..4549099) Escherichia coli O157:H7 str. EC4115 6970254 YP_002273024.1 CDS dppC NC_011353.1 4549110 4550012 R identified by match to protein family HMM PF00528; dipeptide transporter complement(4549110..4550012) Escherichia coli O157:H7 str. EC4115 6969468 YP_002273025.1 CDS dppB NC_011353.1 4550022 4551167 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(4550022..4551167) Escherichia coli O157:H7 str. EC4115 6970111 YP_002273026.1 CDS ECH74115_4913 NC_011353.1 4551059 4551202 D identified by glimmer; hypothetical protein 4551059..4551202 Escherichia coli O157:H7 str. EC4115 6969133 YP_002273027.1 CDS dppA NC_011353.1 4551192 4552799 R identified by match to protein family HMM PF00496; dipeptide ABC transporter substrate-binding protein complement(4551192..4552799) Escherichia coli O157:H7 str. EC4115 6967851 YP_002273028.1 CDS ECH74115_4916 NC_011353.1 4553712 4555403 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(4553712..4555403) Escherichia coli O157:H7 str. EC4115 6972391 YP_002273029.1 CDS ECH74115_4917 NC_011353.1 4555658 4556188 R identified by match to protein family HMM PF00419; protein LpfE complement(4555658..4556188) Escherichia coli O157:H7 str. EC4115 6970440 YP_002273030.1 CDS ECH74115_4918 NC_011353.1 4556193 4557248 R identified by match to protein family HMM PF00419; protein LpfD complement(4556193..4557248) Escherichia coli O157:H7 str. EC4115 6969036 YP_002273031.1 CDS ECH74115_4921 NC_011353.1 4559865 4560554 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC complement(4559865..4560554) Escherichia coli O157:H7 str. EC4115 6967233 YP_002273032.1 CDS ECH74115_4922 NC_011353.1 4560616 4561140 R identified by match to protein family HMM PF00419; fimbrial protein complement(4560616..4561140) Escherichia coli O157:H7 str. EC4115 6969284 YP_002273033.1 CDS ECH74115_4923 NC_011353.1 4561484 4562686 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890; inner membrane protein YhjX complement(4561484..4562686) Escherichia coli O157:H7 str. EC4115 6968122 YP_002273034.1 CDS ECH74115_4924 NC_011353.1 4562915 4563613 R hypothetical protein complement(4562915..4563613) Escherichia coli O157:H7 str. EC4115 6967640 YP_002273035.1 CDS tag NC_011353.1 4563771 4564334 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 4563771..4564334 Escherichia coli O157:H7 str. EC4115 6967044 YP_002273036.1 CDS ECH74115_4927 NC_011353.1 4564331 4564771 D identified by match to protein family HMM PF00583; hypothetical protein 4564331..4564771 Escherichia coli O157:H7 str. EC4115 6966582 YP_002273037.1 CDS bisC NC_011353.1 4564740 4567073 R identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; biotin sulfoxide reductase complement(4564740..4567073) Escherichia coli O157:H7 str. EC4115 6971363 YP_002273038.1 CDS ECH74115_4928 NC_011353.1 4567226 4567885 D identified by match to protein family HMM PF00691; match to protein family HMM PF05433; outer membrane lipoprotein 4567226..4567885 Escherichia coli O157:H7 str. EC4115 6967398 YP_002273039.1 CDS tkrA NC_011353.1 4567989 4568963 D identified by match to protein family HMM PF00389; match to protein family HMM PF02826; 2-ketogluconate reductase 4567989..4568963 Escherichia coli O157:H7 str. EC4115 6972228 YP_002273040.1 CDS ECH74115_4930 NC_011353.1 4569013 4569723 R lipoprotein complement(4569013..4569723) Escherichia coli O157:H7 str. EC4115 6966623 YP_002273041.1 CDS ECH74115_4931 NC_011353.1 4570157 4570447 D transcriptional regulator 4570157..4570447 Escherichia coli O157:H7 str. EC4115 6967390 YP_002273042.1 CDS ECH74115_4932 NC_011353.1 4570728 4570940 D identified by match to protein family HMM PF00313; major cold shock protein 4570728..4570940 Escherichia coli O157:H7 str. EC4115 6971276 YP_002273043.1 CDS hokA NC_011353.1 4571128 4571280 R identified by match to protein family HMM PF01848; small toxic polypeptide complement(4571128..4571280) Escherichia coli O157:H7 str. EC4115 6971563 YP_002273044.1 CDS glyS NC_011353.1 4571603 4573672 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(4571603..4573672) Escherichia coli O157:H7 str. EC4115 6970455 YP_002273045.1 CDS glyQ NC_011353.1 4573682 4574593 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(4573682..4574593) Escherichia coli O157:H7 str. EC4115 6970869 YP_002273046.1 CDS ECH74115_4936 NC_011353.1 4574688 4574987 R hypothetical protein complement(4574688..4574987) Escherichia coli O157:H7 str. EC4115 6967274 YP_002273047.1 CDS ECH74115_4937 NC_011353.1 4575162 4576157 D acyltransferase family protein 4575162..4576157 Escherichia coli O157:H7 str. EC4115 6966648 YP_002273048.1 CDS ECH74115_4938 NC_011353.1 4576199 4576636 R identified by match to protein family HMM PF05360; hypothetical protein complement(4576199..4576636) Escherichia coli O157:H7 str. EC4115 6972094 YP_002273049.1 CDS ECH74115_4939 NC_011353.1 4576682 4577023 R identified by match to protein family HMM PF05360; hypothetical protein complement(4576682..4577023) Escherichia coli O157:H7 str. EC4115 6971476 YP_002273050.1 CDS xylB NC_011353.1 4577192 4578646 R identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase complement(4577192..4578646) Escherichia coli O157:H7 str. EC4115 6970495 YP_002273051.1 CDS xylA NC_011353.1 4578718 4580040 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(4578718..4580040) Escherichia coli O157:H7 str. EC4115 6969880 YP_002273052.1 CDS xylF NC_011353.1 4580406 4581398 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4580406..4581398 Escherichia coli O157:H7 str. EC4115 6971899 YP_002273053.1 CDS xylG NC_011353.1 4581476 4583017 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4581476..4583017 Escherichia coli O157:H7 str. EC4115 6971283 YP_002273054.1 CDS xylH NC_011353.1 4582995 4584176 D identified by match to protein family HMM PF02653; D-xylose ABC transporter permease 4582995..4584176 Escherichia coli O157:H7 str. EC4115 6970675 YP_002273055.1 CDS xylR NC_011353.1 4584254 4585432 D identified by match to protein family HMM PF00165; xylose operon regulatory protein 4584254..4585432 Escherichia coli O157:H7 str. EC4115 6970086 YP_002273056.1 CDS bax NC_011353.1 4585540 4586364 R identified by match to protein family HMM PF01832; hypothetical protein complement(4585540..4586364) Escherichia coli O157:H7 str. EC4115 6969204 YP_002273057.1 CDS malS NC_011353.1 4586684 4588714 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4586684..4588714 Escherichia coli O157:H7 str. EC4115 6968543 YP_002273058.1 CDS avtA NC_011353.1 4588892 4590145 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4588892..4590145 Escherichia coli O157:H7 str. EC4115 6970805 YP_002273059.1 CDS ECH74115_4949 NC_011353.1 4590297 4590770 R identified by match to protein family HMM PF00037; 4Fe-4S binding protein complement(4590297..4590770) Escherichia coli O157:H7 str. EC4115 6969478 YP_002273060.1 CDS ECH74115_4950 NC_011353.1 4591014 4591829 R identified by match to protein family HMM PF00165; match to protein family HMM PF02311; AraC family transcriptional regulator complement(4591014..4591829) Escherichia coli O157:H7 str. EC4115 6968840 YP_002273061.1 CDS ECH74115_4951 NC_011353.1 4592055 4593455 D identified by match to protein family HMM TIGR00792; sugar transporter glycoside-pentoside-hexuronide family 4592055..4593455 Escherichia coli O157:H7 str. EC4115 6968228 YP_002273062.1 CDS ECH74115_4952 NC_011353.1 4593466 4595436 D identified by match to protein family HMM PF07944; hypothetical protein 4593466..4595436 Escherichia coli O157:H7 str. EC4115 6971265 YP_002273063.1 CDS ECH74115_4953 NC_011353.1 4595566 4596306 R identified by match to protein family HMM PF06629; MltA-interacting protein MipA complement(4595566..4596306) Escherichia coli O157:H7 str. EC4115 6970604 YP_002273064.1 CDS ECH74115_4955 NC_011353.1 4596430 4597404 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4596430..4597404 Escherichia coli O157:H7 str. EC4115 6967129 YP_002273065.1 CDS ECH74115_4954 NC_011353.1 4597401 4598537 R identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family complement(4597401..4598537) Escherichia coli O157:H7 str. EC4115 6969898 YP_002273066.1 CDS ECH74115_4956 NC_011353.1 4598543 4598866 R hypothetical protein complement(4598543..4598866) Escherichia coli O157:H7 str. EC4115 6972214 YP_002273067.1 CDS aldB NC_011353.1 4599411 4600949 R identified by match to protein family HMM PF00171; aldehyde dehydrogenase B complement(4599411..4600949) Escherichia coli O157:H7 str. EC4115 6968293 YP_002273068.1 CDS ECH74115_4959 NC_011353.1 4601057 4602352 R identified by match to protein family HMM PF02661; Fic family protein complement(4601057..4602352) Escherichia coli O157:H7 str. EC4115 6968912 YP_002273069.1 CDS adhB NC_011353.1 4602482 4603633 R identified by match to protein family HMM PF00465; alcohol dehydrogenase complement(4602482..4603633) Escherichia coli O157:H7 str. EC4115 6966691 YP_002273070.1 CDS selB NC_011353.1 4603822 4605666 R identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475; selenocysteinyl-tRNA-specific translation factor complement(4603822..4605666) Escherichia coli O157:H7 str. EC4115 6971439 YP_002273071.1 CDS selA NC_011353.1 4605663 4607054 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4605663..4607054) Escherichia coli O157:H7 str. EC4115 6970602 YP_002273072.1 CDS ECH74115_4963 NC_011353.1 4607152 4607760 R identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase complement(4607152..4607760) Escherichia coli O157:H7 str. EC4115 6968154 YP_002273073.1 CDS ECH74115_4964 NC_011353.1 4607759 4607902 D identified by glimmer; hypothetical protein 4607759..4607902 Escherichia coli O157:H7 str. EC4115 6968720 YP_002273074.1 CDS ECH74115_4965 NC_011353.1 4607989 4612218 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; Rhs family protein 4607989..4612218 Escherichia coli O157:H7 str. EC4115 6966670 YP_002273075.1 CDS ECH74115_4966 NC_011353.1 4613566 4613835 D hypothetical protein 4613566..4613835 Escherichia coli O157:H7 str. EC4115 6967186 YP_002273076.1 CDS ECH74115_4967 NC_011353.1 4614294 4615430 R identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family complement(4614294..4615430) Escherichia coli O157:H7 str. EC4115 6971896 YP_002273077.1 CDS ECH74115_4968 NC_011353.1 4615433 4615795 R hypothetical protein complement(4615433..4615795) Escherichia coli O157:H7 str. EC4115 6970884 YP_002273078.1 CDS mtlA NC_011353.1 4616332 4618245 D identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit IIABC 4616332..4618245 Escherichia coli O157:H7 str. EC4115 6970791 YP_002273079.1 CDS mtlD NC_011353.1 4618340 4619488 D identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol-1-phosphate 5-dehydrogenase 4618340..4619488 Escherichia coli O157:H7 str. EC4115 6967731 YP_002273080.1 CDS mtlR NC_011353.1 4619488 4620075 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4619488..4620075 Escherichia coli O157:H7 str. EC4115 6966641 YP_002273081.1 CDS ECH74115_4972 NC_011353.1 4620087 4620296 R hypothetical protein complement(4620087..4620296) Escherichia coli O157:H7 str. EC4115 6971556 YP_002273082.1 CDS ECH74115_4973 NC_011353.1 4620581 4620943 D hypothetical protein 4620581..4620943 Escherichia coli O157:H7 str. EC4115 6971146 YP_002273083.1 CDS ECH74115_4974 NC_011353.1 4621588 4622169 D lipoprotein 4621588..4622169 Escherichia coli O157:H7 str. EC4115 6970303 YP_002273084.1 CDS ECH74115_4975 NC_011353.1 4622213 4626979 D identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; Hep_Hag family protein 4622213..4626979 Escherichia coli O157:H7 str. EC4115 6970910 YP_002273085.1 CDS lldP NC_011353.1 4627347 4629002 D identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 4627347..4629002 Escherichia coli O157:H7 str. EC4115 6968672 YP_002273086.1 CDS ECH74115_4977 NC_011353.1 4629002 4629778 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4629002..4629778 Escherichia coli O157:H7 str. EC4115 6969727 YP_002273087.1 CDS lldD NC_011353.1 4629775 4630965 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4629775..4630965 Escherichia coli O157:H7 str. EC4115 6966815 YP_002273088.1 CDS ECH74115_4979 NC_011353.1 4631151 4631624 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4631151..4631624 Escherichia coli O157:H7 str. EC4115 6967444 YP_002273089.1 CDS cysE NC_011353.1 4631677 4632498 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4631677..4632498) Escherichia coli O157:H7 str. EC4115 6971281 YP_002273090.1 CDS gpsA NC_011353.1 4632578 4633597 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4632578..4633597) Escherichia coli O157:H7 str. EC4115 6971912 YP_002273091.1 CDS secB NC_011353.1 4633597 4634064 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4633597..4634064) Escherichia coli O157:H7 str. EC4115 6969334 YP_002273092.1 CDS grxC NC_011353.1 4634127 4634378 R identified by match to protein family HMM PF00462; match to protein family HMM TIGR02181; glutaredoxin 3 complement(4634127..4634378) Escherichia coli O157:H7 str. EC4115 6969787 YP_002273093.1 CDS ECH74115_4984 NC_011353.1 4634520 4634951 R identified by match to protein family HMM PF00581; rhodanese domain-containing protein complement(4634520..4634951) Escherichia coli O157:H7 str. EC4115 6967748 YP_002273094.1 CDS gpmI NC_011353.1 4635196 4636740 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4635196..4636740 Escherichia coli O157:H7 str. EC4115 6969587 YP_002273095.1 CDS ECH74115_4986 NC_011353.1 4636774 4638033 D identified by match to protein family HMM PF01551; hypothetical protein 4636774..4638033 Escherichia coli O157:H7 str. EC4115 6967153 YP_002273096.1 CDS ECH74115_4987 NC_011353.1 4638037 4638996 D identified by match to protein family HMM PF04748; polysaccharide deacetylase family protein 4638037..4638996 Escherichia coli O157:H7 str. EC4115 6969058 YP_002273097.1 CDS tdh NC_011353.1 4640257 4641282 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4640257..4641282) Escherichia coli O157:H7 str. EC4115 6967787 YP_002273098.1 CDS kbl NC_011353.1 4641292 4642488 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(4641292..4642488) Escherichia coli O157:H7 str. EC4115 6971179 YP_002273099.1 CDS ECH74115_4991 NC_011353.1 4642763 4643620 R identified by match to protein family HMM PF09612; match to protein family HMM TIGR02192; hypothetical protein complement(4642763..4643620) Escherichia coli O157:H7 str. EC4115 6967626 YP_002273100.1 CDS rfaD NC_011353.1 4643924 4644856 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4643924..4644856 Escherichia coli O157:H7 str. EC4115 6969528 YP_002273101.1 CDS rfaF NC_011353.1 4644866 4645912 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4644866..4645912 Escherichia coli O157:H7 str. EC4115 6971739 YP_002273102.1 CDS rfaC NC_011353.1 4645916 4646908 D identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193; ADP-heptose--LPS heptosyltransferase 4645916..4646908 Escherichia coli O157:H7 str. EC4115 6969335 YP_002273103.1 CDS ECH74115_4995 NC_011353.1 4646905 4648113 D identified by match to protein family HMM PF04932; lipid A-core:surface polymer ligase 4646905..4648113 Escherichia coli O157:H7 str. EC4115 6971098 YP_002273104.1 CDS ECH74115_4996 NC_011353.1 4648149 4649291 R identified by match to protein family HMM PF00534; lipopolysaccharide 1,2-N-acetylglucosaminetransferase complement(4648149..4649291) Escherichia coli O157:H7 str. EC4115 6970330 YP_002273105.1 CDS ECH74115_4997 NC_011353.1 4649300 4650313 R identified by match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,2-glucosyltransferase complement(4649300..4650313) Escherichia coli O157:H7 str. EC4115 6972029 YP_002273106.1 CDS ECH74115_4998 NC_011353.1 4650338 4650844 R identified by match to protein family HMM PF06176; lipopolysaccharide core biosynthesis protein complement(4650338..4650844) Escherichia coli O157:H7 str. EC4115 6969047 YP_002273107.1 CDS ECH74115_4999 NC_011353.1 4651071 4652078 R identified by match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,3-galactosyltransferase complement(4651071..4652078) Escherichia coli O157:H7 str. EC4115 6968589 YP_002273108.1 CDS rfaP NC_011353.1 4652121 4652918 R identified by match to protein family HMM PF06293; lipopolysaccharide core biosynthesis protein RfaP complement(4652121..4652918) Escherichia coli O157:H7 str. EC4115 6967798 YP_002273109.1 CDS rfaG NC_011353.1 4652911 4654035 R identified by match to protein family HMM PF00534; lipopolysaccharide core biosynthesis protein RfaG complement(4652911..4654035) Escherichia coli O157:H7 str. EC4115 6967185 YP_002273110.1 CDS rfaQ NC_011353.1 4654032 4655090 R identified by match to protein family HMM PF01075; match to protein family HMM TIGR02201; lipopolysaccharide core biosynthesis protein complement(4654032..4655090) Escherichia coli O157:H7 str. EC4115 6971115 YP_002273111.1 CDS waaA NC_011353.1 4655503 4656780 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4655503..4656780 Escherichia coli O157:H7 str. EC4115 6967262 YP_002273112.1 CDS coaD NC_011353.1 4656788 4657267 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4656788..4657267 Escherichia coli O157:H7 str. EC4115 6971920 YP_002273113.1 CDS mutM NC_011353.1 4657306 4658115 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4657306..4658115) Escherichia coli O157:H7 str. EC4115 6966708 YP_002273114.1 CDS rpmG NC_011353.1 4658213 4658380 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4658213..4658380) Escherichia coli O157:H7 str. EC4115 6969954 YP_002273115.1 CDS rpmB NC_011353.1 4658401 4658637 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4658401..4658637) Escherichia coli O157:H7 str. EC4115 6972213 YP_002273116.1 CDS radC NC_011353.1 4658854 4659522 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4658854..4659522) Escherichia coli O157:H7 str. EC4115 6968243 YP_002273117.1 CDS coaBC NC_011353.1 4659622 4660914 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4659622..4660914 Escherichia coli O157:H7 str. EC4115 6970507 YP_002273118.1 CDS dut NC_011353.1 4660892 4661350 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4660892..4661350 Escherichia coli O157:H7 str. EC4115 6966689 YP_002273119.1 CDS slmA NC_011353.1 4661457 4662053 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4661457..4662053 Escherichia coli O157:H7 str. EC4115 6967229 YP_002273120.1 CDS pyrE NC_011353.1 4662090 4662731 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4662090..4662731) Escherichia coli O157:H7 str. EC4115 6971081 YP_002273121.1 CDS rph NC_011353.1 4662797 4663513 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4662797..4663513) Escherichia coli O157:H7 str. EC4115 6967425 YP_002273122.1 CDS ECH74115_5014 NC_011353.1 4663640 4664503 D identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255; hypothetical protein 4663640..4664503 Escherichia coli O157:H7 str. EC4115 6970423 YP_002273123.1 CDS ECH74115_5015 NC_011353.1 4664520 4664660 R identified by glimmer; hypothetical protein complement(4664520..4664660) Escherichia coli O157:H7 str. EC4115 6967203 YP_002273124.1 CDS dinD NC_011353.1 4664724 4665548 D DNA-damage-inducible protein D 4664724..4665548 Escherichia coli O157:H7 str. EC4115 6970877 YP_002273125.1 CDS ECH74115_5018 NC_011353.1 4665840 4666457 D identified by match to protein family HMM PF03458; hypothetical protein 4665840..4666457 Escherichia coli O157:H7 str. EC4115 6971677 YP_002273126.1 CDS ligB NC_011353.1 4666454 4668187 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4666454..4668187) Escherichia coli O157:H7 str. EC4115 6969435 YP_002273127.1 CDS ECH74115_5019 NC_011353.1 4667997 4668254 R hypothetical protein complement(4667997..4668254) Escherichia coli O157:H7 str. EC4115 6969002 YP_002273128.1 CDS gmk NC_011353.1 4668394 4669017 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4668394..4669017 Escherichia coli O157:H7 str. EC4115 6967610 YP_002273129.1 CDS rpoZ NC_011353.1 4669072 4669347 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4669072..4669347 Escherichia coli O157:H7 str. EC4115 6968206 YP_002273130.1 CDS spoT NC_011353.1 4669366 4671474 D identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4669366..4671474 Escherichia coli O157:H7 str. EC4115 6971216 YP_002273131.1 CDS trmH NC_011353.1 4671481 4672170 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4671481..4672170 Escherichia coli O157:H7 str. EC4115 6972201 YP_002273132.1 CDS recG NC_011353.1 4672176 4674257 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4672176..4674257 Escherichia coli O157:H7 str. EC4115 6969949 YP_002273133.1 CDS ECH74115_5024 NC_011353.1 4674242 4675108 R hypothetical protein complement(4674242..4675108) Escherichia coli O157:H7 str. EC4115 6968202 YP_002273134.1 CDS gltS NC_011353.1 4675111 4676316 R identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium/glutamate symporter complement(4675111..4676316) Escherichia coli O157:H7 str. EC4115 6970578 YP_002273135.1 CDS yicE NC_011353.1 4676596 4677987 D identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine permease 4676596..4677987 Escherichia coli O157:H7 str. EC4115 6969005 YP_002273136.1 CDS ECH74115_5028 NC_011353.1 4678108 4679817 D identified by match to protein family HMM PF05170; AsmA family protein 4678108..4679817 Escherichia coli O157:H7 str. EC4115 6966657 YP_002273137.1 CDS yicI NC_011353.1 4679870 4682188 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(4679870..4682188) Escherichia coli O157:H7 str. EC4115 6967102 YP_002273138.1 CDS ECH74115_5030 NC_011353.1 4682198 4683580 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4682198..4683580) Escherichia coli O157:H7 str. EC4115 6967930 YP_002273139.1 CDS ECH74115_5032 NC_011353.1 4684091 4685344 D identified by match to protein family HMM PF00589; integrase 4684091..4685344 Escherichia coli O157:H7 str. EC4115 6972422 YP_002273140.1 CDS ECH74115_5033 NC_011353.1 4685479 4685793 D identified by match to protein family HMM PF01527; IS911 transposase orfA 4685479..4685793 Escherichia coli O157:H7 str. EC4115 6972009 YP_002273141.1 CDS ECH74115_5034 NC_011353.1 4685913 4686659 D identified by match to protein family HMM PF00665; IS911 transposase orfB 4685913..4686659 Escherichia coli O157:H7 str. EC4115 6968425 YP_002273142.1 CDS ECH74115_5035 NC_011353.1 4686677 4686820 D Aec75 4686677..4686820 Escherichia coli O157:H7 str. EC4115 6969311 YP_002273143.1 CDS ECH74115_5036 NC_011353.1 4686910 4687284 D identified by match to protein family HMM PF06755; hypothetical protein 4686910..4687284 Escherichia coli O157:H7 str. EC4115 6970991 YP_002273144.1 CDS ECH74115_5037 NC_011353.1 4687281 4687772 D hypothetical protein 4687281..4687772 Escherichia coli O157:H7 str. EC4115 6971564 YP_002273145.1 CDS ECH74115_5041 NC_011353.1 4689403 4689564 D IS66 family element, orf1 4689403..4689564 Escherichia coli O157:H7 str. EC4115 6967048 YP_002273146.1 CDS ECH74115_5042 NC_011353.1 4689561 4689908 D identified by match to protein family HMM PF05717; IS66 family element, orf2 4689561..4689908 Escherichia coli O157:H7 str. EC4115 6967666 YP_002273147.1 CDS ECH74115_5043 NC_011353.1 4689958 4691496 D identified by match to protein family HMM PF03050; IS66 family element, transposase 4689958..4691496 Escherichia coli O157:H7 str. EC4115 6971725 YP_002273148.1 CDS ECH74115_5044 NC_011353.1 4691936 4692055 R identified by glimmer; hypothetical protein complement(4691936..4692055) Escherichia coli O157:H7 str. EC4115 6970901 YP_002273149.1 CDS ECH74115_5045 NC_011353.1 4692361 4692798 R identified by match to protein family HMM PF04806; protein EspF complement(4692361..4692798) Escherichia coli O157:H7 str. EC4115 6970416 YP_002273150.1 CDS ECH74115_5046 NC_011353.1 4692821 4692973 D identified by glimmer; hypothetical protein 4692821..4692973 Escherichia coli O157:H7 str. EC4115 6971775 YP_002273151.1 CDS eprI NC_011353.1 4693476 4693697 R identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105; type III secretion apparatus needle protein complement(4693476..4693697) Escherichia coli O157:H7 str. EC4115 6971543 YP_002273152.1 CDS ECH74115_5048 NC_011353.1 4693733 4694140 R hypothetical protein complement(4693733..4694140) Escherichia coli O157:H7 str. EC4115 6971376 YP_002273153.1 CDS ECH74115_5049 NC_011353.1 4694147 4694941 R identified by match to protein family HMM PF05802; protein EspB complement(4694147..4694941) Escherichia coli O157:H7 str. EC4115 6967428 YP_002273154.1 CDS ECH74115_5050 NC_011353.1 4695106 4696230 R identified by match to protein family HMM PF04888; protein EspD complement(4695106..4696230) Escherichia coli O157:H7 str. EC4115 6966626 YP_002273155.1 CDS ECH74115_5051 NC_011353.1 4696243 4696680 R identified by match to protein family HMM PF03433; protein EspA complement(4696243..4696680) Escherichia coli O157:H7 str. EC4115 6969069 YP_002273156.1 CDS ECH74115_5052 NC_011353.1 4696880 4697935 R identified by match to protein family HMM PF07018; match to protein family HMM TIGR02511; protein SepL complement(4696880..4697935) Escherichia coli O157:H7 str. EC4115 6968437 YP_002273157.1 CDS ECH74115_5053 NC_011353.1 4698078 4699298 D identified by match to protein family HMM TIGR02500; type III secretion apparatus protein, YscD/HrpQ family 4698078..4699298 Escherichia coli O157:H7 str. EC4115 6968057 YP_002273158.1 CDS ECH74115_5054 NC_011353.1 4699562 4702366 R identified by match to protein family HMM PF01476; match to protein family HMM PF02368; match to protein family HMM PF02369; match to protein family HMM PF07979; intimin C-type lectin domain-containing protein complement(4699562..4702366) Escherichia coli O157:H7 str. EC4115 6970294 YP_002273159.1 CDS ECH74115_5055 NC_011353.1 4702426 4702896 R identified by match to protein family HMM PF05932; Tir chaperone complement(4702426..4702896) Escherichia coli O157:H7 str. EC4115 6970029 YP_002273160.1 CDS ECH74115_5056 NC_011353.1 4703034 4704710 R identified by match to protein family HMM PF03549; match to protein family HMM PF07489; match to protein family HMM PF07490; Tir complement(4703034..4704710) Escherichia coli O157:H7 str. EC4115 6969208 YP_002273161.1 CDS ECH74115_5057 NC_011353.1 4705134 4705619 R identified by match to protein family HMM PF03278; Map protein complement(4705134..4705619) Escherichia coli O157:H7 str. EC4115 6969006 YP_002273162.1 CDS ECH74115_5058 NC_011353.1 4706011 4706394 D hypothetical protein 4706011..4706394 Escherichia coli O157:H7 str. EC4115 6968008 YP_002273163.1 CDS ECH74115_5059 NC_011353.1 4706592 4707098 R hypothetical protein complement(4706592..4707098) Escherichia coli O157:H7 str. EC4115 6970622 YP_002273164.1 CDS ECH74115_5060 NC_011353.1 4707129 4708046 R protein SepQ complement(4707129..4708046) Escherichia coli O157:H7 str. EC4115 6969820 YP_002273165.1 CDS ECH74115_5061 NC_011353.1 4708418 4708738 R ST25 protein complement(4708418..4708738) Escherichia coli O157:H7 str. EC4115 6972164 YP_002273166.1 CDS ECH74115_5062 NC_011353.1 4708798 4710138 R identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546; type III secretion apparatus H+-transporting two-sector ATPase complement(4708798..4710138) Escherichia coli O157:H7 str. EC4115 6971369 YP_002273167.1 CDS ECH74115_5063 NC_011353.1 4710122 4712149 R identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399; type III secretion protein, HrcV family complement(4710122..4712149) Escherichia coli O157:H7 str. EC4115 6967364 YP_002273168.1 CDS ECH74115_5064 NC_011353.1 4712146 4712499 R ST22 protein complement(4712146..4712499) Escherichia coli O157:H7 str. EC4115 6966864 YP_002273169.1 CDS ECH74115_5065 NC_011353.1 4712662 4712805 R identified by glimmer; hypothetical protein complement(4712662..4712805) Escherichia coli O157:H7 str. EC4115 6968924 YP_002273170.1 CDS ECH74115_5066 NC_011353.1 4713447 4714019 D identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544; type III secretion apparatus lipoprotein, YscJ/HrcJ family 4713447..4714019 Escherichia coli O157:H7 str. EC4115 6970730 YP_002273171.1 CDS ECH74115_5067 NC_011353.1 4714175 4714336 R identified by glimmer; hypothetical protein complement(4714175..4714336) Escherichia coli O157:H7 str. EC4115 6970654 YP_002273172.1 CDS ECH74115_5068 NC_011353.1 4714361 4714480 D protein SepD 4714361..4714480 Escherichia coli O157:H7 str. EC4115 6971280 YP_002273173.1 CDS ECH74115_5069 NC_011353.1 4714480 4716018 D identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516; type III secretion outer membrane pore, YscC/HrcC family 4714480..4716018 Escherichia coli O157:H7 str. EC4115 6971911 YP_002273174.1 CDS ECH74115_5070 NC_011353.1 4717339 4717710 R negative regulator GrlR complement(4717339..4717710) Escherichia coli O157:H7 str. EC4115 6966693 YP_002273175.1 CDS ECH74115_5072 NC_011353.1 4717906 4718364 D identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 4717906..4718364 Escherichia coli O157:H7 str. EC4115 6968021 YP_002273176.1 CDS ECH74115_5071 NC_011353.1 4718361 4719398 R member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli; secretion system apparatus protein SsaU complement(4718361..4719398) Escherichia coli O157:H7 str. EC4115 6969853 YP_002273177.1 CDS epaR NC_011353.1 4719391 4720167 R identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401; type III secretion apparatus protein SpaR/YscT/HrcT complement(4719391..4720167) Escherichia coli O157:H7 str. EC4115 6969015 YP_002273178.1 CDS ECH74115_5074 NC_011353.1 4720167 4720292 R EscS protein complement(4720167..4720292) Escherichia coli O157:H7 str. EC4115 6970461 YP_002273179.1 CDS epaP NC_011353.1 4720436 4721089 R part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein complement(4720436..4721089) Escherichia coli O157:H7 str. EC4115 6971938 YP_002273180.1 CDS ECH74115_5076 NC_011353.1 4721094 4721747 R hypothetical protein complement(4721094..4721747) Escherichia coli O157:H7 str. EC4115 6969131 YP_002273181.1 CDS ECH74115_5077 NC_011353.1 4721734 4721877 R hypothetical protein complement(4721734..4721877) Escherichia coli O157:H7 str. EC4115 6970280 YP_002273182.1 CDS ECH74115_5078 NC_011353.1 4722330 4722644 R hypothetical protein complement(4722330..4722644) Escherichia coli O157:H7 str. EC4115 6971088 YP_002273183.1 CDS ECH74115_5079 NC_011353.1 4722657 4722875 R identified by match to protein family HMM TIGR02501; type III secretion system protein, YseE family complement(4722657..4722875) Escherichia coli O157:H7 str. EC4115 6971526 YP_002273184.1 CDS ECH74115_5080 NC_011353.1 4722890 4723261 R identified by match to protein family HMM PF00816; hypothetical protein complement(4722890..4723261) Escherichia coli O157:H7 str. EC4115 6971692 YP_002273185.1 CDS ECH74115_5081 NC_011353.1 4724575 4725720 D identified by match to protein family HMM PF06872; protein EspG 4724575..4725720 Escherichia coli O157:H7 str. EC4115 6967145 YP_002273186.1 CDS ECH74115_5082 NC_011353.1 4725848 4726666 D identified by match to protein family HMM PF06977; sdiA-regulated domain-containing protein 4725848..4726666 Escherichia coli O157:H7 str. EC4115 6967645 YP_002273187.1 CDS ECH74115_5083 NC_011353.1 4727060 4727173 R identified by glimmer; hypothetical protein complement(4727060..4727173) Escherichia coli O157:H7 str. EC4115 6968453 YP_002273188.1 CDS ECH74115_5084 NC_011353.1 4727438 4727623 R hypothetical protein complement(4727438..4727623) Escherichia coli O157:H7 str. EC4115 6968460 YP_002273189.1 CDS ECH74115_5085 NC_011353.1 4727686 4728609 D identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; carboxylate/amino acid/amine transporter 4727686..4728609 Escherichia coli O157:H7 str. EC4115 6969628 YP_002273190.1 CDS nlpA NC_011353.1 4728613 4729431 R identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; hypothetical protein complement(4728613..4729431) Escherichia coli O157:H7 str. EC4115 6967997 YP_002273191.1 CDS ECH74115_5087 NC_011353.1 4729428 4729571 R hypothetical protein complement(4729428..4729571) Escherichia coli O157:H7 str. EC4115 6970435 YP_002273192.1 CDS ECH74115_5088 NC_011353.1 4729653 4729946 D hypothetical protein 4729653..4729946 Escherichia coli O157:H7 str. EC4115 6970696 YP_002273193.1 CDS ECH74115_5090 NC_011353.1 4731411 4731764 D identified by match to protein family HMM PF06296; hypothetical protein 4731411..4731764 Escherichia coli O157:H7 str. EC4115 6972025 YP_002273194.1 CDS ECH74115_5091 NC_011353.1 4731748 4732071 D identified by match to protein family HMM PF01381; DNA-binding protein 4731748..4732071 Escherichia coli O157:H7 str. EC4115 6971493 YP_002273195.1 CDS ECH74115_5092 NC_011353.1 4732187 4732639 R identified by match to protein family HMM PF06711; hypothetical protein complement(4732187..4732639) Escherichia coli O157:H7 str. EC4115 6969135 YP_002273196.1 CDS ade NC_011353.1 4734200 4735966 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4734200..4735966 Escherichia coli O157:H7 str. EC4115 6969467 YP_002273197.1 CDS uhpT NC_011353.1 4736012 4737403 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4736012..4737403) Escherichia coli O157:H7 str. EC4115 6971712 YP_002273198.1 CDS uhpC NC_011353.1 4737541 4738860 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4737541..4738860) Escherichia coli O157:H7 str. EC4115 6967113 YP_002273199.1 CDS uhpB NC_011353.1 4738870 4740375 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4738870..4740375) Escherichia coli O157:H7 str. EC4115 6967523 YP_002273200.1 CDS uhpA NC_011353.1 4740372 4740962 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4740372..4740962) Escherichia coli O157:H7 str. EC4115 6967960 YP_002273201.1 CDS ilvN NC_011353.1 4744381 4744671 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4744381..4744671) Escherichia coli O157:H7 str. EC4115 6971263 YP_002273202.1 CDS ilvB NC_011353.1 4744675 4746363 R identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase catalytic subunit complement(4744675..4746363) Escherichia coli O157:H7 str. EC4115 6966647 YP_002273203.1 CDS emrD NC_011353.1 4747495 4748685 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4747495..4748685 Escherichia coli O157:H7 str. EC4115 6967803 YP_002273204.1 CDS ECH74115_5106 NC_011353.1 4748693 4749190 R hypothetical protein complement(4748693..4749190) Escherichia coli O157:H7 str. EC4115 6967351 YP_002273205.1 CDS ECH74115_5107 NC_011353.1 4749187 4749549 R hypothetical protein complement(4749187..4749549) Escherichia coli O157:H7 str. EC4115 6966751 YP_002273206.1 CDS ECH74115_5108 NC_011353.1 4749539 4749886 R identified by match to protein family HMM PF02656; hypothetical protein complement(4749539..4749886) Escherichia coli O157:H7 str. EC4115 6971989 YP_002273207.1 CDS ECH74115_5109 NC_011353.1 4749995 4750444 D hypothetical protein 4749995..4750444 Escherichia coli O157:H7 str. EC4115 6971224 YP_002273208.1 CDS ECH74115_5110 NC_011353.1 4750491 4751984 R identified by match to protein family HMM PF00884; sulfatase complement(4750491..4751984) Escherichia coli O157:H7 str. EC4115 6970733 YP_002273209.1 CDS ECH74115_5111 NC_011353.1 4751981 4753696 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4751981..4753696) Escherichia coli O157:H7 str. EC4115 6970232 YP_002273210.1 CDS ECH74115_5113 NC_011353.1 4753863 4754756 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4753863..4754756 Escherichia coli O157:H7 str. EC4115 6970969 YP_002273211.1 CDS glvA NC_011353.1 4754753 4756075 R identified by match to protein family HMM PF02056; maltose-6'-phosphate glucosidase complement(4754753..4756075) Escherichia coli O157:H7 str. EC4115 6970112 YP_002273212.1 CDS ECH74115_5114 NC_011353.1 4756075 4757691 R identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005; PTS system, alpha-glucoside-specific transporter subunit IIBC complement(4756075..4757691) Escherichia coli O157:H7 str. EC4115 6967792 YP_002273213.1 CDS ECH74115_5116 NC_011353.1 4757987 4758703 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4757987..4758703 Escherichia coli O157:H7 str. EC4115 6971320 YP_002273214.1 CDS ECH74115_5115 NC_011353.1 4758700 4760385 R identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein complement(4758700..4760385) Escherichia coli O157:H7 str. EC4115 6967871 YP_002273215.1 CDS ECH74115_5117 NC_011353.1 4760403 4760552 D identified by glimmer; hypothetical protein 4760403..4760552 Escherichia coli O157:H7 str. EC4115 6967074 YP_002273216.1 CDS ibpB NC_011353.1 4760557 4760985 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4760557..4760985) Escherichia coli O157:H7 str. EC4115 6968557 YP_002273217.1 CDS ibpA NC_011353.1 4761097 4761510 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4761097..4761510) Escherichia coli O157:H7 str. EC4115 6966675 YP_002273218.1 CDS ECH74115_5120 NC_011353.1 4761770 4761928 R hypothetical protein complement(4761770..4761928) Escherichia coli O157:H7 str. EC4115 6970411 YP_002273219.1 CDS ECH74115_5121 NC_011353.1 4761888 4762148 D identified by match to protein family HMM PF07119; hypothetical protein 4761888..4762148 Escherichia coli O157:H7 str. EC4115 6968011 YP_002273220.1 CDS ECH74115_5122 NC_011353.1 4762150 4763400 R hypothetical protein complement(4762150..4763400) Escherichia coli O157:H7 str. EC4115 6971662 YP_002273221.1 CDS ECH74115_5123 NC_011353.1 4763465 4764529 D FAD/NAD(P)-binding domain; oxidoreductase 4763465..4764529 Escherichia coli O157:H7 str. EC4115 6969957 YP_002273222.1 CDS ECH74115_5124 NC_011353.1 4764775 4765431 D identified by glimmer; hypothetical protein 4764775..4765431 Escherichia coli O157:H7 str. EC4115 6969194 YP_002273223.1 CDS yidA NC_011353.1 4765477 4766289 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4765477..4766289) Escherichia coli O157:H7 str. EC4115 6966773 YP_002273224.1 CDS ECH74115_5126 NC_011353.1 4766404 4766802 R identified by match to protein family HMM PF06078; hypothetical protein complement(4766404..4766802) Escherichia coli O157:H7 str. EC4115 6970028 YP_002273225.1 CDS gyrB NC_011353.1 4767042 4769459 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4767042..4769459) Escherichia coli O157:H7 str. EC4115 6970462 YP_002273226.1 CDS recF NC_011353.1 4769485 4770558 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4769485..4770558) Escherichia coli O157:H7 str. EC4115 6967459 YP_002273227.1 CDS dnaN NC_011353.1 4770558 4771658 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4770558..4771658) Escherichia coli O157:H7 str. EC4115 6968467 YP_002273228.1 CDS dnaA NC_011353.1 4771663 4773066 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4771663..4773066) Escherichia coli O157:H7 str. EC4115 6971639 YP_002273229.1 CDS ECH74115_5131 NC_011353.1 4773360 4773560 R identified by glimmer; hypothetical protein complement(4773360..4773560) Escherichia coli O157:H7 str. EC4115 6966584 YP_002273230.1 CDS ECH74115_5132 NC_011353.1 4773580 4773720 R identified by glimmer; hypothetical protein complement(4773580..4773720) Escherichia coli O157:H7 str. EC4115 6968232 YP_002273231.1 CDS rpmH NC_011353.1 4773673 4773813 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4773673..4773813 Escherichia coli O157:H7 str. EC4115 6968738 YP_002273232.1 CDS rnpA NC_011353.1 4773830 4774189 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4773830..4774189 Escherichia coli O157:H7 str. EC4115 6967746 YP_002273233.1 CDS ECH74115_5135 NC_011353.1 4774413 4776059 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4774413..4776059 Escherichia coli O157:H7 str. EC4115 6967440 YP_002273234.1 CDS trmE NC_011353.1 4776165 4777529 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4776165..4777529 Escherichia coli O157:H7 str. EC4115 6971346 YP_002273235.1 CDS ECH74115_5138 NC_011353.1 4777860 4779848 R identified by match to protein family HMM PF07906; ShET2 enterotoxin, N- region family complement(4777860..4779848) Escherichia coli O157:H7 str. EC4115 6969763 YP_002273236.1 CDS tnaA NC_011353.1 4780534 4781949 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4780534..4781949 Escherichia coli O157:H7 str. EC4115 6972188 YP_002273237.1 CDS tnaB NC_011353.1 4782040 4783287 D tryptophan transporter of low affinity; tryptophan permease TnaB 4782040..4783287 Escherichia coli O157:H7 str. EC4115 6968487 YP_002273238.1 CDS mdtL NC_011353.1 4783419 4784594 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4783419..4784594 Escherichia coli O157:H7 str. EC4115 6970740 YP_002273239.1 CDS ECH74115_5142 NC_011353.1 4784569 4785528 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4784569..4785528 Escherichia coli O157:H7 str. EC4115 6966557 YP_002273240.1 CDS ECH74115_5143 NC_011353.1 4785685 4786434 D hypothetical protein 4785685..4786434 Escherichia coli O157:H7 str. EC4115 6968753 YP_002273241.1 CDS ECH74115_5144 NC_011353.1 4786456 4787022 D identified by match to protein family HMM PF03358; NADPH-dependent FMN reductase 4786456..4787022 Escherichia coli O157:H7 str. EC4115 6969895 YP_002273242.1 CDS ECH74115_5145 NC_011353.1 4787076 4788413 R identified by match to protein family HMM PF00860; inorganic anion transporter sulfate permease (SulP) family complement(4787076..4788413) Escherichia coli O157:H7 str. EC4115 6972151 YP_002273243.1 CDS ECH74115_5146 NC_011353.1 4788579 4789244 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4788579..4789244 Escherichia coli O157:H7 str. EC4115 6970977 YP_002273244.1 CDS ECH74115_5147 NC_011353.1 4789381 4791789 R identified by glimmer; hypothetical protein complement(4789381..4791789) Escherichia coli O157:H7 str. EC4115 6967506 YP_002273245.1 CDS ECH74115_5149 NC_011353.1 4793110 4793277 D hypothetical protein 4793110..4793277 Escherichia coli O157:H7 str. EC4115 6969692 YP_002273246.1 CDS ECH74115_5150 NC_011353.1 4793376 4793555 R hypothetical protein complement(4793376..4793555) Escherichia coli O157:H7 str. EC4115 6969073 YP_002273247.1 CDS phoU NC_011353.1 4796656 4797381 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4796656..4797381) Escherichia coli O157:H7 str. EC4115 6969366 YP_002273248.1 CDS pstB NC_011353.1 4797396 4798169 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4797396..4798169) Escherichia coli O157:H7 str. EC4115 6967548 YP_002273249.1 CDS pstA NC_011353.1 4798352 4799242 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4798352..4799242) Escherichia coli O157:H7 str. EC4115 6966699 YP_002273250.1 CDS pstC NC_011353.1 4799242 4800201 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4799242..4800201) Escherichia coli O157:H7 str. EC4115 6971806 YP_002273251.1 CDS pstS NC_011353.1 4800288 4801328 R identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter substrate-binding protein complement(4800288..4801328) Escherichia coli O157:H7 str. EC4115 6970506 YP_002273252.1 CDS ECH74115_5158 NC_011353.1 4801395 4801511 D identified by glimmer; hypothetical protein 4801395..4801511 Escherichia coli O157:H7 str. EC4115 6971431 YP_002273253.1 CDS ECH74115_5159 NC_011353.1 4801540 4802622 R identified by match to protein family HMM PF00419; fimbrial family protein complement(4801540..4802622) Escherichia coli O157:H7 str. EC4115 6972242 YP_002273254.1 CDS ECH74115_5160 NC_011353.1 4802650 4803720 R fimbrial protein complement(4802650..4803720) Escherichia coli O157:H7 str. EC4115 6969383 YP_002273255.1 CDS ECH74115_5161 NC_011353.1 4803732 4806266 R identified by match to protein family HMM PF00577; fimbrial usher protein complement(4803732..4806266) Escherichia coli O157:H7 str. EC4115 6966625 YP_002273256.1 CDS ECH74115_5164 NC_011353.1 4807077 4807679 R identified by match to protein family HMM PF00419; fimbrial protein complement(4807077..4807679) Escherichia coli O157:H7 str. EC4115 6971091 YP_002273257.1 CDS glmS NC_011353.1 4808379 4810208 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4808379..4810208) Escherichia coli O157:H7 str. EC4115 6971713 YP_002273258.1 CDS glmU NC_011353.1 4810370 4811740 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4810370..4811740) Escherichia coli O157:H7 str. EC4115 6968564 YP_002273259.1 CDS atpC NC_011353.1 4812092 4812511 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(4812092..4812511) Escherichia coli O157:H7 str. EC4115 6970187 YP_002273260.1 CDS atpD NC_011353.1 4812532 4813914 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(4812532..4813914) Escherichia coli O157:H7 str. EC4115 6970775 YP_002273261.1 CDS atpG NC_011353.1 4813941 4814804 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(4813941..4814804) Escherichia coli O157:H7 str. EC4115 6971826 YP_002273262.1 CDS atpA NC_011353.1 4814855 4816396 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(4814855..4816396) Escherichia coli O157:H7 str. EC4115 6971034 YP_002273263.1 CDS atpH NC_011353.1 4816409 4816942 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(4816409..4816942) Escherichia coli O157:H7 str. EC4115 6971830 YP_002273264.1 CDS atpF NC_011353.1 4816957 4817427 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(4816957..4817427) Escherichia coli O157:H7 str. EC4115 6967551 YP_002273265.1 CDS atpE NC_011353.1 4817489 4817728 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(4817489..4817728) Escherichia coli O157:H7 str. EC4115 6966985 YP_002273266.1 CDS atpB NC_011353.1 4817775 4818590 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(4817775..4818590) Escherichia coli O157:H7 str. EC4115 6969200 YP_002273267.1 CDS atpI NC_011353.1 4818599 4818817 R identified by match to protein family HMM PF03899; ATP synthase F0, I subunit complement(4818599..4818817) Escherichia coli O157:H7 str. EC4115 6968128 YP_002273268.1 CDS gidB NC_011353.1 4819596 4820219 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4819596..4820219) Escherichia coli O157:H7 str. EC4115 6969858 YP_002273269.1 CDS gidA NC_011353.1 4820283 4822172 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4820283..4822172) Escherichia coli O157:H7 str. EC4115 6970499 YP_002273270.1 CDS mioC NC_011353.1 4822551 4822994 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4822551..4822994) Escherichia coli O157:H7 str. EC4115 6971481 YP_002273271.1 CDS asnC NC_011353.1 4823084 4823542 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4823084..4823542) Escherichia coli O157:H7 str. EC4115 6972116 YP_002273272.1 CDS asnA NC_011353.1 4823694 4824686 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4823694..4824686 Escherichia coli O157:H7 str. EC4115 6970332 YP_002273273.1 CDS yieM NC_011353.1 4824691 4826142 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4824691..4826142) Escherichia coli O157:H7 str. EC4115 6970618 YP_002273274.1 CDS ECH74115_5182 NC_011353.1 4826136 4827632 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4826136..4827632) Escherichia coli O157:H7 str. EC4115 6968935 YP_002273275.1 CDS trkD NC_011353.1 4827855 4829723 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4827855..4829723 Escherichia coli O157:H7 str. EC4115 6969572 YP_002273276.1 CDS rbsD NC_011353.1 4829890 4830309 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4829890..4830309 Escherichia coli O157:H7 str. EC4115 6967815 YP_002273277.1 CDS rbsA NC_011353.1 4830317 4831822 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4830317..4831822 Escherichia coli O157:H7 str. EC4115 6968123 YP_002273278.1 CDS rbsC NC_011353.1 4831827 4832792 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4831827..4832792 Escherichia coli O157:H7 str. EC4115 6971397 YP_002273279.1 CDS rbsB NC_011353.1 4832817 4833707 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4832817..4833707 Escherichia coli O157:H7 str. EC4115 6967761 YP_002273280.1 CDS rbsK NC_011353.1 4833818 4834762 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4833818..4834762 Escherichia coli O157:H7 str. EC4115 6971818 YP_002273281.1 CDS rbsR NC_011353.1 4834766 4835758 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4834766..4835758 Escherichia coli O157:H7 str. EC4115 6969759 YP_002273282.1 CDS ECH74115_5189 NC_011353.1 4835724 4837151 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; drug resistance MFS transporter drug:H+ antiporter-1 (DHA2) family complement(4835724..4837151) Escherichia coli O157:H7 str. EC4115 6971367 YP_002273283.1 CDS ECH74115_5191 NC_011353.1 4837174 4837866 R identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator complement(4837174..4837866) Escherichia coli O157:H7 str. EC4115 6968178 YP_002273284.1 CDS hdfR NC_011353.1 4843669 4844508 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4843669..4844508) Escherichia coli O157:H7 str. EC4115 6972346 YP_002273285.1 CDS ECH74115_5200 NC_011353.1 4844627 4844965 D identified by match to protein family HMM PF04219; hypothetical protein 4844627..4844965 Escherichia coli O157:H7 str. EC4115 6968100 YP_002273286.1 CDS ECH74115_5201 NC_011353.1 4844989 4846509 R among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4844989..4846509) Escherichia coli O157:H7 str. EC4115 6968874 YP_002273287.1 CDS ilvG NC_011353.1 4847100 4848746 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4847100..4848746 Escherichia coli O157:H7 str. EC4115 6968555 YP_002273288.1 CDS ilvM NC_011353.1 4848743 4849006 D acetolactate synthase 2 regulatory subunit 4848743..4849006 Escherichia coli O157:H7 str. EC4115 6969351 YP_002273289.1 CDS ilvE NC_011353.1 4849026 4849955 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4849026..4849955 Escherichia coli O157:H7 str. EC4115 6966957 YP_002273290.1 CDS ilvD NC_011353.1 4850020 4851870 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4850020..4851870 Escherichia coli O157:H7 str. EC4115 6967710 YP_002273291.1 CDS ilvA NC_011353.1 4851873 4853417 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4851873..4853417 Escherichia coli O157:H7 str. EC4115 6968566 YP_002273292.1 CDS ilvY NC_011353.1 4853469 4854362 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4853469..4854362) Escherichia coli O157:H7 str. EC4115 6969301 YP_002273293.1 CDS ilvC NC_011353.1 4854512 4855987 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4854512..4855987 Escherichia coli O157:H7 str. EC4115 6970124 YP_002273294.1 CDS ppiC NC_011353.1 4856033 4856314 R identified by match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase C complement(4856033..4856314) Escherichia coli O157:H7 str. EC4115 6968070 YP_002273295.1 CDS ECH74115_5210 NC_011353.1 4856513 4856962 R hypothetical protein complement(4856513..4856962) Escherichia coli O157:H7 str. EC4115 6971809 YP_002273296.1 CDS rep NC_011353.1 4857179 4859200 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4857179..4859200 Escherichia coli O157:H7 str. EC4115 6969766 YP_002273297.1 CDS gppA NC_011353.1 4859247 4860731 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4859247..4860731) Escherichia coli O157:H7 str. EC4115 6969935 YP_002273298.1 CDS rhlB NC_011353.1 4860867 4862132 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4860867..4862132) Escherichia coli O157:H7 str. EC4115 6968780 YP_002273299.1 CDS trxA NC_011353.1 4862263 4862592 D identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 4862263..4862592 Escherichia coli O157:H7 str. EC4115 6968478 YP_002273300.1 CDS rho NC_011353.1 4862919 4864178 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4862919..4864178 Escherichia coli O157:H7 str. EC4115 6967884 YP_002273301.1 CDS ECH74115_5216 NC_011353.1 4864212 4864406 D identified by glimmer; hypothetical protein 4864212..4864406 Escherichia coli O157:H7 str. EC4115 6971874 YP_002273302.1 CDS wecA NC_011353.1 4864418 4865521 D identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 4864418..4865521 Escherichia coli O157:H7 str. EC4115 6971966 YP_002273303.1 CDS ECH74115_5218 NC_011353.1 4865533 4866579 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4865533..4866579 Escherichia coli O157:H7 str. EC4115 6971747 YP_002273304.1 CDS ECH74115_5219 NC_011353.1 4866635 4867765 D identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 4866635..4867765 Escherichia coli O157:H7 str. EC4115 6970996 YP_002273305.1 CDS wecC NC_011353.1 4867762 4869024 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4867762..4869024 Escherichia coli O157:H7 str. EC4115 6970765 YP_002273306.1 CDS rfbB2 NC_011353.1 4869024 4870091 D identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 4869024..4870091 Escherichia coli O157:H7 str. EC4115 6969387 YP_002273307.1 CDS rfbA1 NC_011353.1 4870110 4870991 D identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 4870110..4870991 Escherichia coli O157:H7 str. EC4115 6970774 YP_002273308.1 CDS wecD NC_011353.1 4870969 4871643 D identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382; TDP-fucosamine acetyltransferase 4870969..4871643 Escherichia coli O157:H7 str. EC4115 6971607 YP_002273309.1 CDS wecE NC_011353.1 4871648 4872778 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4871648..4872778 Escherichia coli O157:H7 str. EC4115 6971312 YP_002273310.1 CDS ECH74115_5225 NC_011353.1 4872780 4874030 D identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 4872780..4874030 Escherichia coli O157:H7 str. EC4115 6972101 YP_002273311.1 CDS wecF NC_011353.1 4874027 4875106 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4874027..4875106 Escherichia coli O157:H7 str. EC4115 6966797 YP_002273312.1 CDS wzyE NC_011353.1 4875103 4876455 D enterobacterial common antigen polymerase; common antigen polymerase 4875103..4876455 Escherichia coli O157:H7 str. EC4115 6967624 YP_002273313.1 CDS ECH74115_5228 NC_011353.1 4876458 4877198 D identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosaminuronic acid transferase 4876458..4877198 Escherichia coli O157:H7 str. EC4115 6968837 YP_002273314.1 CDS ECH74115_5229 NC_011353.1 4877389 4878774 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4877389..4878774 Escherichia coli O157:H7 str. EC4115 6969644 YP_002273315.1 CDS aslB NC_011353.1 4879686 4880921 D identified by match to protein family HMM PF04055; arylsulfatase-activating protein AslB 4879686..4880921 Escherichia coli O157:H7 str. EC4115 6972341 YP_002273316.1 CDS aslA NC_011353.1 4881089 4882744 R identified by match to protein family HMM PF00884; arylsulfatase complement(4881089..4882744) Escherichia coli O157:H7 str. EC4115 6970829 YP_002273317.1 CDS ECH74115_5238 NC_011353.1 4882887 4883024 R identified by glimmer; hypothetical protein complement(4882887..4883024) Escherichia coli O157:H7 str. EC4115 6970358 YP_002273318.1 CDS hemY NC_011353.1 4883423 4884619 R identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540; protoheme IX biogenesis protein complement(4883423..4884619) Escherichia coli O157:H7 str. EC4115 6972287 YP_002273319.1 CDS ECH74115_5241 NC_011353.1 4884622 4885839 R identified by match to protein family HMM PF04375; uroporphyrinogen III C-methyltransferase complement(4884622..4885839) Escherichia coli O157:H7 str. EC4115 6966834 YP_002273320.1 CDS hemD NC_011353.1 4885861 4886601 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4885861..4886601) Escherichia coli O157:H7 str. EC4115 6969038 YP_002273321.1 CDS hemC NC_011353.1 4886598 4887554 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4886598..4887554) Escherichia coli O157:H7 str. EC4115 6971305 YP_002273322.1 CDS cyaA NC_011353.1 4887926 4890472 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4887926..4890472 Escherichia coli O157:H7 str. EC4115 6967809 YP_002273323.1 CDS cyaY NC_011353.1 4890512 4890832 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4890512..4890832) Escherichia coli O157:H7 str. EC4115 6967384 YP_002273324.1 CDS ECH74115_5246 NC_011353.1 4890947 4891108 D hypothetical protein 4890947..4891108 Escherichia coli O157:H7 str. EC4115 6971117 YP_002273325.1 CDS ECH74115_5247 NC_011353.1 4891295 4891498 D lipoprotein 4891295..4891498 Escherichia coli O157:H7 str. EC4115 6971726 YP_002273326.1 CDS dapF NC_011353.1 4891535 4892359 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4891535..4892359 Escherichia coli O157:H7 str. EC4115 6969586 YP_002273327.1 CDS ECH74115_5249 NC_011353.1 4892356 4893063 D identified by match to protein family HMM PF04340; hypothetical protein 4892356..4893063 Escherichia coli O157:H7 str. EC4115 6970503 YP_002273328.1 CDS xerC NC_011353.1 4893060 4893956 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4893060..4893956 Escherichia coli O157:H7 str. EC4115 6970044 YP_002273329.1 CDS ECH74115_5251 NC_011353.1 4893956 4894672 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4893956..4894672 Escherichia coli O157:H7 str. EC4115 6968602 YP_002273330.1 CDS uvrD NC_011353.1 4894756 4896918 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4894756..4896918 Escherichia coli O157:H7 str. EC4115 6970680 YP_002273331.1 CDS ECH74115_5253 NC_011353.1 4896963 4897865 R identified by match to protein family HMM PF01887; hypothetical protein complement(4896963..4897865) Escherichia coli O157:H7 str. EC4115 6966874 YP_002273332.1 CDS ECH74115_5254 NC_011353.1 4897948 4898712 R hypothetical protein complement(4897948..4898712) Escherichia coli O157:H7 str. EC4115 6968745 YP_002273333.1 CDS ECH74115_5255 NC_011353.1 4898725 4898838 D identified by glimmer; hypothetical protein 4898725..4898838 Escherichia coli O157:H7 str. EC4115 6967314 YP_002273334.1 CDS corA NC_011353.1 4899082 4900032 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4899082..4900032 Escherichia coli O157:H7 str. EC4115 6967764 YP_002273335.1 CDS ECH74115_5257 NC_011353.1 4900074 4900496 R identified by match to protein family HMM PF06092; hypothetical protein complement(4900074..4900496) Escherichia coli O157:H7 str. EC4115 6970037 YP_002273336.1 CDS ECH74115_5258 NC_011353.1 4900562 4901410 R identified by match to protein family HMM TIGR03034; hypothetical protein complement(4900562..4901410) Escherichia coli O157:H7 str. EC4115 6971889 YP_002273337.1 CDS ECH74115_5259 NC_011353.1 4901546 4901743 D identified by glimmer; hypothetical protein 4901546..4901743 Escherichia coli O157:H7 str. EC4115 6966673 YP_002273338.1 CDS rarD NC_011353.1 4902716 4903603 R identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; RarD protein complement(4902716..4903603) Escherichia coli O157:H7 str. EC4115 6967373 YP_002273339.1 CDS ECH74115_5261 NC_011353.1 4903655 4904122 R identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein complement(4903655..4904122) Escherichia coli O157:H7 str. EC4115 6968960 YP_002273340.1 CDS pldA NC_011353.1 4904287 4905156 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4904287..4905156 Escherichia coli O157:H7 str. EC4115 6969437 YP_002273341.1 CDS recQ NC_011353.1 4905283 4907118 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4905283..4907118 Escherichia coli O157:H7 str. EC4115 6970470 YP_002273342.1 CDS rhtC NC_011353.1 4907188 4907802 D identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; threonine efflux system 4907188..4907802 Escherichia coli O157:H7 str. EC4115 6971270 YP_002273343.1 CDS rhtB NC_011353.1 4907864 4908484 R identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/homoserine lactone efflux protein complement(4907864..4908484) Escherichia coli O157:H7 str. EC4115 6967826 YP_002273344.1 CDS pldB NC_011353.1 4908595 4909617 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4908595..4909617 Escherichia coli O157:H7 str. EC4115 6968076 YP_002273345.1 CDS ECH74115_5267 NC_011353.1 4909625 4910425 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4909625..4910425 Escherichia coli O157:H7 str. EC4115 6969104 YP_002273346.1 CDS ECH74115_5268 NC_011353.1 4910507 4911262 R hypothetical protein complement(4910507..4911262) Escherichia coli O157:H7 str. EC4115 6970085 YP_002273347.1 CDS metR NC_011353.1 4911288 4912241 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator MetR complement(4911288..4912241) Escherichia coli O157:H7 str. EC4115 6970573 YP_002273348.1 CDS metE NC_011353.1 4912477 4914738 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4912477..4914738 Escherichia coli O157:H7 str. EC4115 6970563 YP_002273349.1 CDS ECH74115_5271 NC_011353.1 4914778 4915593 R identified by match to protein family HMM PF01738; dienelactone hydrolase family protein complement(4914778..4915593) Escherichia coli O157:H7 str. EC4115 6968321 YP_002273350.1 CDS udp NC_011353.1 4915855 4916616 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4915855..4916616 Escherichia coli O157:H7 str. EC4115 6969278 YP_002273351.1 CDS rmuC NC_011353.1 4916757 4918184 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4916757..4918184 Escherichia coli O157:H7 str. EC4115 6966672 YP_002273352.1 CDS ubiE NC_011353.1 4918279 4919034 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4918279..4919034 Escherichia coli O157:H7 str. EC4115 6970851 YP_002273353.1 CDS ECH74115_5275 NC_011353.1 4919048 4919653 D identified by match to protein family HMM PF02036; hypothetical protein 4919048..4919653 Escherichia coli O157:H7 str. EC4115 6971647 YP_002273354.1 CDS ubiB NC_011353.1 4919650 4921290 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4919650..4921290 Escherichia coli O157:H7 str. EC4115 6972027 YP_002273355.1 CDS tatA NC_011353.1 4921369 4921638 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4921369..4921638 Escherichia coli O157:H7 str. EC4115 6970404 YP_002273356.1 CDS tatB NC_011353.1 4921642 4922157 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4921642..4922157 Escherichia coli O157:H7 str. EC4115 6969926 YP_002273357.1 CDS tatC NC_011353.1 4922160 4922936 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4922160..4922936 Escherichia coli O157:H7 str. EC4115 6971996 YP_002273358.1 CDS tatD NC_011353.1 4922966 4923760 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4922966..4923760 Escherichia coli O157:H7 str. EC4115 6970948 YP_002273359.1 CDS rfaH NC_011353.1 4923757 4924245 R identified by match to protein family HMM PF02357; match to protein family HMM TIGR01955; transcriptional activator RfaH complement(4923757..4924245) Escherichia coli O157:H7 str. EC4115 6968671 YP_002273360.1 CDS ubiD NC_011353.1 4924412 4925905 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4924412..4925905 Escherichia coli O157:H7 str. EC4115 6967477 YP_002273361.1 CDS fre NC_011353.1 4925951 4926652 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4925951..4926652 Escherichia coli O157:H7 str. EC4115 6968043 YP_002273362.1 CDS fadA NC_011353.1 4926844 4928007 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4926844..4928007) Escherichia coli O157:H7 str. EC4115 6968549 YP_002273363.1 CDS fadB NC_011353.1 4928017 4930206 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4928017..4930206) Escherichia coli O157:H7 str. EC4115 6969439 YP_002273364.1 CDS pepQ NC_011353.1 4930396 4931727 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4930396..4931727 Escherichia coli O157:H7 str. EC4115 6970191 YP_002273365.1 CDS ECH74115_5287 NC_011353.1 4931724 4932341 D identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 4931724..4932341 Escherichia coli O157:H7 str. EC4115 6969464 YP_002273366.1 CDS trkH NC_011353.1 4932380 4933831 D identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; potassium transporter 4932380..4933831 Escherichia coli O157:H7 str. EC4115 6971834 YP_002273367.1 CDS hemG NC_011353.1 4933843 4934388 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4933843..4934388 Escherichia coli O157:H7 str. EC4115 6968783 YP_002273368.1 CDS mobB NC_011353.1 4939973 4940500 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein MobB complement(4939973..4940500) Escherichia coli O157:H7 str. EC4115 6972281 YP_002273369.1 CDS mobA NC_011353.1 4940482 4941066 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4940482..4941066) Escherichia coli O157:H7 str. EC4115 6969451 YP_002273370.1 CDS ECH74115_5298 NC_011353.1 4941136 4941405 D identified by match to protein family HMM PF06288; hypothetical protein 4941136..4941405 Escherichia coli O157:H7 str. EC4115 6971868 YP_002273371.1 CDS ECH74115_5299 NC_011353.1 4941482 4942468 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4941482..4942468 Escherichia coli O157:H7 str. EC4115 6971079 YP_002273372.1 CDS dsbA NC_011353.1 4942485 4943111 D identified by match to protein family HMM PF01323; protein disulfide isomerase I 4942485..4943111 Escherichia coli O157:H7 str. EC4115 6967123 YP_002273373.1 CDS ECH74115_5301 NC_011353.1 4943136 4943276 D identified by glimmer; hypothetical protein 4943136..4943276 Escherichia coli O157:H7 str. EC4115 6972044 YP_002273374.1 CDS ECH74115_5302 NC_011353.1 4943266 4944696 D identified by match to protein family HMM PF06097; hypothetical protein 4943266..4944696 Escherichia coli O157:H7 str. EC4115 6967942 YP_002273375.1 CDS ECH74115_5303 NC_011353.1 4944737 4945693 R identified by match to protein family HMM PF01553; acyltransferase complement(4944737..4945693) Escherichia coli O157:H7 str. EC4115 6967925 YP_002273376.1 CDS ECH74115_5304 NC_011353.1 4945581 4945733 D identified by glimmer; hypothetical protein 4945581..4945733 Escherichia coli O157:H7 str. EC4115 6968299 YP_002273377.1 CDS ECH74115_5305 NC_011353.1 4945789 4945908 R identified by glimmer; hypothetical protein complement(4945789..4945908) Escherichia coli O157:H7 str. EC4115 6968872 YP_002273378.1 CDS polA NC_011353.1 4946033 4948819 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4946033..4948819 Escherichia coli O157:H7 str. EC4115 6966611 YP_002273379.1 CDS ECH74115_5307 NC_011353.1 4949038 4949181 R identified by glimmer; hypothetical protein complement(4949038..4949181) Escherichia coli O157:H7 str. EC4115 6972316 YP_002273380.1 CDS engB NC_011353.1 4949201 4949833 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4949201..4949833) Escherichia coli O157:H7 str. EC4115 6972099 YP_002273381.1 CDS ECH74115_5311 NC_011353.1 4950415 4950921 D identified by match to protein family HMM PF04220; hypothetical protein 4950415..4950921 Escherichia coli O157:H7 str. EC4115 6972299 YP_002273382.1 CDS ECH74115_5312 NC_011353.1 4950995 4951111 R identified by glimmer; hypothetical protein complement(4950995..4951111) Escherichia coli O157:H7 str. EC4115 6970501 YP_002273383.1 CDS hemN NC_011353.1 4951110 4952483 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4951110..4952483 Escherichia coli O157:H7 str. EC4115 6968245 YP_002273384.1 CDS glnG NC_011353.1 4952895 4954313 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4952895..4954313) Escherichia coli O157:H7 str. EC4115 6967293 YP_002273385.1 CDS glnL NC_011353.1 4954316 4955365 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4954316..4955365) Escherichia coli O157:H7 str. EC4115 6971163 YP_002273386.1 CDS glnA NC_011353.1 4955539 4956948 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4955539..4956948) Escherichia coli O157:H7 str. EC4115 6971992 YP_002273387.1 CDS typA NC_011353.1 4957321 4959144 D identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein 4957321..4959144 Escherichia coli O157:H7 str. EC4115 6971248 YP_002273388.1 CDS ECH74115_5318 NC_011353.1 4959361 4960071 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4959361..4960071 Escherichia coli O157:H7 str. EC4115 6969191 YP_002273389.1 CDS ECH74115_5319 NC_011353.1 4960079 4961059 D identified by match to protein family HMM PF01261; AP endonuclease, family 2 4960079..4961059 Escherichia coli O157:H7 str. EC4115 6968382 YP_002273390.1 CDS ECH74115_5320 NC_011353.1 4961161 4962426 D identified by match to protein family HMM PF07690; major facilitator family transporter 4961161..4962426 Escherichia coli O157:H7 str. EC4115 6967929 YP_002273391.1 CDS ompL NC_011353.1 4962517 4963209 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(4962517..4963209) Escherichia coli O157:H7 str. EC4115 6967130 YP_002273392.1 CDS ECH74115_5322 NC_011353.1 4963276 4964679 R identified by match to protein family HMM TIGR00792; sugar (Glycoside-Pentoside-Hexuronide) transporter family protein complement(4963276..4964679) Escherichia coli O157:H7 str. EC4115 6971620 YP_002273393.1 CDS ECH74115_5323 NC_011353.1 4964719 4966104 R identified by match to protein family HMM TIGR00792; sugar transporter family protein complement(4964719..4966104) Escherichia coli O157:H7 str. EC4115 6970834 YP_002273394.1 CDS ECH74115_5324 NC_011353.1 4966150 4968186 R identified by match to protein family HMM PF01055; alpha-glucosidase complement(4966150..4968186) Escherichia coli O157:H7 str. EC4115 6970397 YP_002273395.1 CDS ECH74115_5325 NC_011353.1 4968294 4969169 R identified by match to protein family HMM PF01925; membrane protein complement(4968294..4969169) Escherichia coli O157:H7 str. EC4115 6969600 YP_002273396.1 CDS ECH74115_5326 NC_011353.1 4969230 4970132 R identified by match to protein family HMM PF01263; aldose-1-epimerase family protein complement(4969230..4970132) Escherichia coli O157:H7 str. EC4115 6967198 YP_002273397.1 CDS ECH74115_5327 NC_011353.1 4970199 4971440 R identified by match to protein family HMM PF07221; N-acylglucosamine 2-epimerase complement(4970199..4971440) Escherichia coli O157:H7 str. EC4115 6967844 YP_002273398.1 CDS ECH74115_5328 NC_011353.1 4971456 4972334 R identified by match to protein family HMM PF01791; deoxyribose-phosphate aldolase complement(4971456..4972334) Escherichia coli O157:H7 str. EC4115 6971765 YP_002273399.1 CDS ECH74115_5329 NC_011353.1 4972358 4973254 R identified by match to protein family HMM PF03446; 3-hydroxyisobutyrate dehydrogenase complement(4972358..4973254) Escherichia coli O157:H7 str. EC4115 6969401 YP_002273400.1 CDS ECH74115_5330 NC_011353.1 4973422 4974318 D identified by match to protein family HMM PF00294; kinase, PfkB family 4973422..4974318 Escherichia coli O157:H7 str. EC4115 6970497 YP_002273401.1 CDS ECH74115_5331 NC_011353.1 4974328 4975137 D identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; transcriptional regulator, DeoR/GntR family 4974328..4975137 Escherichia coli O157:H7 str. EC4115 6968187 YP_002273402.1 CDS yihX NC_011353.1 4975236 4975835 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; phosphatase 4975236..4975835 Escherichia coli O157:H7 str. EC4115 6969230 YP_002273403.1 CDS rbn NC_011353.1 4975829 4976701 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4975829..4976701 Escherichia coli O157:H7 str. EC4115 6966939 YP_002273404.1 CDS dtd NC_011353.1 4976698 4977135 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4976698..4977135 Escherichia coli O157:H7 str. EC4115 6969275 YP_002273405.1 CDS ECH74115_5335 NC_011353.1 4977132 4978121 D identified by match to protein family HMM PF00583; match to protein family HMM PF09500; match to protein family HMM TIGR02447; GNAT family acetyltransferase 4977132..4978121 Escherichia coli O157:H7 str. EC4115 6967045 YP_002273406.1 CDS ECH74115_5339 NC_011353.1 4981040 4981258 D identified by match to protein family HMM PF01402; ribbon-helix-helix protein, copG family 4981040..4981258 Escherichia coli O157:H7 str. EC4115 6967704 YP_002273407.1 CDS ECH74115_5340 NC_011353.1 4981475 4981717 D hypothetical protein 4981475..4981717 Escherichia coli O157:H7 str. EC4115 6967327 YP_002273408.1 CDS fdhE NC_011353.1 4982047 4982976 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4982047..4982976) Escherichia coli O157:H7 str. EC4115 6966631 YP_002273409.1 CDS fdoI NC_011353.1 4982973 4983608 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4982973..4983608) Escherichia coli O157:H7 str. EC4115 6971364 YP_002273410.1 CDS fdoH NC_011353.1 4983605 4984507 R identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase-O, iron-sulfur subunit complement(4983605..4984507) Escherichia coli O157:H7 str. EC4115 6970194 YP_002273411.1 CDS fdhD NC_011353.1 4987764 4988597 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4987764..4988597 Escherichia coli O157:H7 str. EC4115 6971880 YP_002273412.1 CDS ECH74115_5347 NC_011353.1 4988751 4989806 D lipoprotein 4988751..4989806 Escherichia coli O157:H7 str. EC4115 6969672 YP_002273413.1 CDS ECH74115_5348 NC_011353.1 4989856 4991604 R repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein complement(4989856..4991604) Escherichia coli O157:H7 str. EC4115 6970481 YP_002273414.1 CDS ECH74115_5349 NC_011353.1 4991604 4992674 R with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX complement(4991604..4992674) Escherichia coli O157:H7 str. EC4115 6968569 YP_002273415.1 CDS ECH74115_5350 NC_011353.1 4992664 4994109 R identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427; PTS system transporter subunits IIBC complement(4992664..4994109) Escherichia coli O157:H7 str. EC4115 6967149 YP_002273416.1 CDS ECH74115_5351 NC_011353.1 4994114 4994560 R with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA complement(4994114..4994560) Escherichia coli O157:H7 str. EC4115 6967928 YP_002273417.1 CDS rafY2 NC_011353.1 4995038 4996432 D glycoporin RafY 4995038..4996432 Escherichia coli O157:H7 str. EC4115 6967534 YP_002273418.1 CDS rhaU NC_011353.1 4996473 4996787 R identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625; L-rhamnose 1-epimerase complement(4996473..4996787) Escherichia coli O157:H7 str. EC4115 6970832 YP_002273419.1 CDS rhaD NC_011353.1 4996797 4997621 R identified by match to protein family HMM PF00596; match to protein family HMM TIGR02624; rhamnulose-1-phosphate aldolase complement(4996797..4997621) Escherichia coli O157:H7 str. EC4115 6971257 YP_002273420.1 CDS rhaA NC_011353.1 4997796 4999055 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4997796..4999055) Escherichia coli O157:H7 str. EC4115 6972016 YP_002273421.1 CDS rhaB NC_011353.1 4999052 5000521 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4999052..5000521) Escherichia coli O157:H7 str. EC4115 6966779 YP_002273422.1 CDS ECH74115_5357 NC_011353.1 5000600 5000749 D identified by glimmer; hypothetical protein 5000600..5000749 Escherichia coli O157:H7 str. EC4115 6966920 YP_002273423.1 CDS rhaS NC_011353.1 5000809 5001645 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 5000809..5001645 Escherichia coli O157:H7 str. EC4115 6968119 YP_002273424.1 CDS rhaR NC_011353.1 5001629 5002567 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 5001629..5002567 Escherichia coli O157:H7 str. EC4115 6968742 YP_002273425.1 CDS sodA NC_011353.1 5003883 5004503 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 5003883..5004503 Escherichia coli O157:H7 str. EC4115 6971008 YP_002273426.1 CDS ECH74115_5363 NC_011353.1 5004544 5004660 R hypothetical protein complement(5004544..5004660) Escherichia coli O157:H7 str. EC4115 6971811 YP_002273427.1 CDS kdgT NC_011353.1 5004763 5005746 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 5004763..5005746 Escherichia coli O157:H7 str. EC4115 6969523 YP_002273428.1 CDS ECH74115_5365 NC_011353.1 5005895 5006569 D identified by match to protein family HMM PF03473; match to protein family HMM PF03475; hypothetical protein 5005895..5006569 Escherichia coli O157:H7 str. EC4115 6970704 YP_002273429.1 CDS cpxA NC_011353.1 5006675 5008048 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(5006675..5008048) Escherichia coli O157:H7 str. EC4115 6972233 YP_002273430.1 CDS cpxR NC_011353.1 5008045 5008743 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(5008045..5008743) Escherichia coli O157:H7 str. EC4115 6969838 YP_002273431.1 CDS cpxP NC_011353.1 5008893 5009393 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 5008893..5009393 Escherichia coli O157:H7 str. EC4115 6967961 YP_002273432.1 CDS fieF NC_011353.1 5009542 5010444 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 5009542..5010444 Escherichia coli O157:H7 str. EC4115 6968763 YP_002273433.1 CDS pfkA NC_011353.1 5010625 5011587 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 5010625..5011587 Escherichia coli O157:H7 str. EC4115 6966774 YP_002273434.1 CDS ECH74115_5371 NC_011353.1 5011696 5011878 R hypothetical protein complement(5011696..5011878) Escherichia coli O157:H7 str. EC4115 6967546 YP_002273435.1 CDS sbp NC_011353.1 5011906 5012895 D identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate transporter subunit 5011906..5012895 Escherichia coli O157:H7 str. EC4115 6971262 YP_002273436.1 CDS cdh NC_011353.1 5013002 5013757 D identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672; CDP-diacylglycerol pyrophosphatase 5013002..5013757 Escherichia coli O157:H7 str. EC4115 6971906 YP_002273437.1 CDS tpiA NC_011353.1 5013812 5014579 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(5013812..5014579) Escherichia coli O157:H7 str. EC4115 6971243 YP_002273438.1 CDS ECH74115_5375 NC_011353.1 5014687 5015286 R identified by match to protein family HMM PF07305; hypothetical protein complement(5014687..5015286) Escherichia coli O157:H7 str. EC4115 6971909 YP_002273439.1 CDS ECH74115_5376 NC_011353.1 5015387 5015827 D identified by match to protein family HMM PF05656; hypothetical protein 5015387..5015827 Escherichia coli O157:H7 str. EC4115 6970049 YP_002273440.1 CDS ECH74115_5377 NC_011353.1 5016039 5016338 D identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein 5016039..5016338 Escherichia coli O157:H7 str. EC4115 6970505 YP_002273441.1 CDS uspD NC_011353.1 5016365 5016793 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 5016365..5016793 Escherichia coli O157:H7 str. EC4115 6967859 YP_002273442.1 CDS fpr NC_011353.1 5016798 5017544 R identified by match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP reductase complement(5016798..5017544) Escherichia coli O157:H7 str. EC4115 6971190 YP_002273443.1 CDS glpX NC_011353.1 5017641 5018651 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(5017641..5018651) Escherichia coli O157:H7 str. EC4115 6972174 YP_002273444.1 CDS glpK NC_011353.1 5018881 5020389 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(5018881..5020389) Escherichia coli O157:H7 str. EC4115 6969929 YP_002273445.1 CDS glpF NC_011353.1 5020412 5021257 R identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein complement(5020412..5021257) Escherichia coli O157:H7 str. EC4115 6967983 YP_002273446.1 CDS ECH74115_5383 NC_011353.1 5021689 5021928 D identified by match to protein family HMM PF06005; hypothetical protein 5021689..5021928 Escherichia coli O157:H7 str. EC4115 6968779 YP_002273447.1 CDS ECH74115_5384 NC_011353.1 5021967 5022374 R identified by glimmer; hypothetical protein complement(5021967..5022374) Escherichia coli O157:H7 str. EC4115 6966715 YP_002273448.1 CDS ECH74115_5385 NC_011353.1 5022716 5023390 R identified by glimmer; hypothetical protein complement(5022716..5023390) Escherichia coli O157:H7 str. EC4115 6967320 YP_002273449.1 CDS rraA NC_011353.1 5023450 5023935 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(5023450..5023935) Escherichia coli O157:H7 str. EC4115 6967413 YP_002273450.1 CDS menA NC_011353.1 5024028 5024966 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(5024028..5024966) Escherichia coli O157:H7 str. EC4115 6968067 YP_002273451.1 CDS hslU NC_011353.1 5025021 5026352 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(5025021..5026352) Escherichia coli O157:H7 str. EC4115 6971956 YP_002273452.1 CDS hslV NC_011353.1 5026362 5026892 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(5026362..5026892) Escherichia coli O157:H7 str. EC4115 6966869 YP_002273453.1 CDS ftsN NC_011353.1 5026985 5027944 R identified by match to protein family HMM PF05036; match to protein family HMM TIGR02223; cell division protein FtsN complement(5026985..5027944) Escherichia coli O157:H7 str. EC4115 6970753 YP_002273454.1 CDS cytR NC_011353.1 5028036 5029028 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(5028036..5029028) Escherichia coli O157:H7 str. EC4115 6971331 YP_002273455.1 CDS ECH74115_5392 NC_011353.1 5029027 5029143 D identified by glimmer; hypothetical protein 5029027..5029143 Escherichia coli O157:H7 str. EC4115 6968009 YP_002273456.1 CDS priA NC_011353.1 5029217 5031415 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(5029217..5031415) Escherichia coli O157:H7 str. EC4115 6970095 YP_002273457.1 CDS rpmE NC_011353.1 5031618 5031830 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 5031618..5031830 Escherichia coli O157:H7 str. EC4115 6969861 YP_002273458.1 CDS ECH74115_5395 NC_011353.1 5031990 5036174 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 5031990..5036174 Escherichia coli O157:H7 str. EC4115 6970752 YP_002273459.1 CDS ECH74115_5397 NC_011353.1 5037405 5038013 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(5037405..5038013) Escherichia coli O157:H7 str. EC4115 6967790 YP_002273460.1 CDS metJ NC_011353.1 5038073 5038390 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(5038073..5038390) Escherichia coli O157:H7 str. EC4115 6968411 YP_002273461.1 CDS metB NC_011353.1 5038667 5039827 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 5038667..5039827 Escherichia coli O157:H7 str. EC4115 6969039 YP_002273462.1 CDS metL NC_011353.1 5039830 5042262 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 5039830..5042262 Escherichia coli O157:H7 str. EC4115 6969769 YP_002273463.1 CDS ECH74115_5401 NC_011353.1 5042401 5042535 R identified by glimmer; hypothetical protein complement(5042401..5042535) Escherichia coli O157:H7 str. EC4115 6970613 YP_002273464.1 CDS metF NC_011353.1 5042611 5043501 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 5042611..5043501 Escherichia coli O157:H7 str. EC4115 6971419 YP_002273465.1 CDS katG NC_011353.1 5043830 5046010 D identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 5043830..5046010 Escherichia coli O157:H7 str. EC4115 6972248 YP_002273466.1 CDS ECH74115_5404 NC_011353.1 5046104 5047009 D identified by match to protein family HMM PF00892; transporter 5046104..5047009 Escherichia coli O157:H7 str. EC4115 6966633 YP_002273467.1 CDS ECH74115_5405 NC_011353.1 5047036 5047653 R identified by match to protein family HMM PF06940; hypothetical protein complement(5047036..5047653) Escherichia coli O157:H7 str. EC4115 6967383 YP_002273468.1 CDS gldA NC_011353.1 5047927 5049030 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(5047927..5049030) Escherichia coli O157:H7 str. EC4115 6967692 YP_002273469.1 CDS fsaB NC_011353.1 5049041 5049703 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(5049041..5049703) Escherichia coli O157:H7 str. EC4115 6967055 YP_002273470.1 CDS ptsA NC_011353.1 5049715 5052216 R identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; multi-phosphoryl transfer protein 2 complement(5049715..5052216) Escherichia coli O157:H7 str. EC4115 6971778 YP_002273471.1 CDS ECH74115_5409 NC_011353.1 5052525 5053604 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 5052525..5053604 Escherichia coli O157:H7 str. EC4115 6971033 YP_002273472.1 CDS ECH74115_5410 NC_011353.1 5053619 5053939 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit IIB 5053619..5053939 Escherichia coli O157:H7 str. EC4115 6969565 YP_002273473.1 CDS pflD NC_011353.1 5053990 5056287 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 5053990..5056287 Escherichia coli O157:H7 str. EC4115 6971655 YP_002273474.1 CDS ECH74115_5412 NC_011353.1 5056292 5057131 D identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate lyase II activase 5056292..5057131 Escherichia coli O157:H7 str. EC4115 6969363 YP_002273475.1 CDS ECH74115_5414 NC_011353.1 5057133 5057474 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 5057133..5057474 Escherichia coli O157:H7 str. EC4115 6968546 YP_002273476.1 CDS ECH74115_5413 NC_011353.1 5057461 5058312 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(5057461..5058312) Escherichia coli O157:H7 str. EC4115 6966946 YP_002273477.1 CDS ECH74115_5415 NC_011353.1 5058527 5060260 R identified by match to protein family HMM PF00884; hypothetical protein complement(5058527..5060260) Escherichia coli O157:H7 str. EC4115 6971825 YP_002273478.1 CDS ppc NC_011353.1 5060443 5063094 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(5060443..5063094) Escherichia coli O157:H7 str. EC4115 6967943 YP_002273479.1 CDS argE NC_011353.1 5063446 5064597 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(5063446..5064597) Escherichia coli O157:H7 str. EC4115 6968760 YP_002273480.1 CDS argC NC_011353.1 5064751 5065755 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 5064751..5065755 Escherichia coli O157:H7 str. EC4115 6970003 YP_002273481.1 CDS argB NC_011353.1 5065766 5066539 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 5065766..5066539 Escherichia coli O157:H7 str. EC4115 6970810 YP_002273482.1 CDS argH NC_011353.1 5066600 5067973 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 5066600..5067973 Escherichia coli O157:H7 str. EC4115 6970046 YP_002273483.1 CDS oxyR NC_011353.1 5068240 5069157 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 5068240..5069157 Escherichia coli O157:H7 str. EC4115 6972315 YP_002273484.1 CDS sthA NC_011353.1 5069140 5070540 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(5069140..5070540) Escherichia coli O157:H7 str. EC4115 6972131 YP_002273485.1 CDS ECH74115_5424 NC_011353.1 5070870 5072036 D identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; hippuricase 5070870..5072036 Escherichia coli O157:H7 str. EC4115 6971475 YP_002273486.1 CDS ECH74115_5425 NC_011353.1 5072079 5073395 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator superfamily protein 5072079..5073395 Escherichia coli O157:H7 str. EC4115 6968680 YP_002273487.1 CDS fabR NC_011353.1 5073445 5074149 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 5073445..5074149 Escherichia coli O157:H7 str. EC4115 6967165 YP_002273488.1 CDS ECH74115_5427 NC_011353.1 5074149 5074508 D identified by match to protein family HMM PF07226; hypothetical protein 5074149..5074508 Escherichia coli O157:H7 str. EC4115 6967181 YP_002273489.1 CDS trmA NC_011353.1 5074548 5075648 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(5074548..5075648) Escherichia coli O157:H7 str. EC4115 6967833 YP_002273490.1 CDS btuB NC_011353.1 5076017 5077861 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 5076017..5077861 Escherichia coli O157:H7 str. EC4115 6968480 YP_002273491.1 CDS murI NC_011353.1 5077875 5078663 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 5077875..5078663 Escherichia coli O157:H7 str. EC4115 6969079 YP_002273492.1 CDS murB NC_011353.1 5084187 5085215 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 5084187..5085215 Escherichia coli O157:H7 str. EC4115 6972277 YP_002273493.1 CDS birA NC_011353.1 5085212 5086177 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 5085212..5086177 Escherichia coli O157:H7 str. EC4115 6967399 YP_002273494.1 CDS coaA NC_011353.1 5086206 5087132 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(5086206..5087132) Escherichia coli O157:H7 str. EC4115 6971035 YP_002273495.1 CDS ECH74115_5440 NC_011353.1 5087139 5087333 D hypothetical protein 5087139..5087333 Escherichia coli O157:H7 str. EC4115 6967931 YP_002273496.1 CDS tuf1 NC_011353.1 5088074 5089258 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 5088074..5089258 Escherichia coli O157:H7 str. EC4115 6972383 YP_002273497.1 CDS secE NC_011353.1 5089488 5089871 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 5089488..5089871 Escherichia coli O157:H7 str. EC4115 6972187 YP_002273498.1 CDS nusG NC_011353.1 5089873 5090418 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 5089873..5090418 Escherichia coli O157:H7 str. EC4115 6966900 YP_002273499.1 CDS rplK NC_011353.1 5090577 5091005 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 5090577..5091005 Escherichia coli O157:H7 str. EC4115 6970603 YP_002273500.1 CDS rplA NC_011353.1 5091009 5091713 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 5091009..5091713 Escherichia coli O157:H7 str. EC4115 6971047 YP_002273501.1 CDS rplJ NC_011353.1 5092005 5092502 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 5092005..5092502 Escherichia coli O157:H7 str. EC4115 6967760 YP_002273502.1 CDS rplL NC_011353.1 5092569 5092934 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 5092569..5092934 Escherichia coli O157:H7 str. EC4115 6971461 YP_002273503.1 CDS rpoB NC_011353.1 5093254 5097282 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 5093254..5097282 Escherichia coli O157:H7 str. EC4115 6972258 YP_002273504.1 CDS rpoC NC_011353.1 5097359 5101582 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 5097359..5101582 Escherichia coli O157:H7 str. EC4115 6966776 YP_002273505.1 CDS thiH NC_011353.1 5102673 5103806 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(5102673..5103806) Escherichia coli O157:H7 str. EC4115 6972325 YP_002273506.1 CDS thiG NC_011353.1 5103803 5104618 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(5103803..5104618) Escherichia coli O157:H7 str. EC4115 6967235 YP_002273507.1 CDS thiS NC_011353.1 5104575 5104775 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(5104575..5104775) Escherichia coli O157:H7 str. EC4115 6967770 YP_002273508.1 CDS thiF NC_011353.1 5104759 5105514 R identified by match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356; thiazole biosynthesis adenylyltransferase ThiF complement(5104759..5105514) Escherichia coli O157:H7 str. EC4115 6968444 YP_002273509.1 CDS thiE NC_011353.1 5105507 5106142 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(5105507..5106142) Escherichia coli O157:H7 str. EC4115 6969054 YP_002273510.1 CDS thiC NC_011353.1 5106142 5108037 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(5106142..5108037) Escherichia coli O157:H7 str. EC4115 6969670 YP_002273511.1 CDS rsd NC_011353.1 5108270 5108746 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(5108270..5108746) Escherichia coli O157:H7 str. EC4115 6970350 YP_002273512.1 CDS nudC NC_011353.1 5108841 5109614 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 5108841..5109614 Escherichia coli O157:H7 str. EC4115 6967824 YP_002273513.1 CDS hemE NC_011353.1 5109654 5110718 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 5109654..5110718 Escherichia coli O157:H7 str. EC4115 6971373 YP_002273514.1 CDS nfi NC_011353.1 5110728 5111399 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 5110728..5111399 Escherichia coli O157:H7 str. EC4115 6969370 YP_002273515.1 CDS ECH74115_5468 NC_011353.1 5111442 5112032 D identified by match to protein family HMM PF04222; hypothetical protein 5111442..5112032 Escherichia coli O157:H7 str. EC4115 6967003 YP_002273516.1 CDS hupA NC_011353.1 5112219 5112491 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 5112219..5112491 Escherichia coli O157:H7 str. EC4115 6969092 YP_002273517.1 CDS ECH74115_5470 NC_011353.1 5112564 5113199 D identified by match to protein family HMM PF07356; hypothetical protein 5112564..5113199 Escherichia coli O157:H7 str. EC4115 6968459 YP_002273518.1 CDS zraP NC_011353.1 5113201 5113626 R zinc resistance protein complement(5113201..5113626) Escherichia coli O157:H7 str. EC4115 6967897 YP_002273519.1 CDS ECH74115_5472 NC_011353.1 5113629 5113757 R identified by glimmer; hypothetical protein complement(5113629..5113757) Escherichia coli O157:H7 str. EC4115 6966593 YP_002273520.1 CDS zraS NC_011353.1 5113864 5115240 D identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein ZraS 5113864..5115240 Escherichia coli O157:H7 str. EC4115 6969128 YP_002273521.1 CDS zraR NC_011353.1 5115237 5116562 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 5115237..5116562 Escherichia coli O157:H7 str. EC4115 6968310 YP_002273522.1 CDS purD NC_011353.1 5116559 5117848 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(5116559..5117848) Escherichia coli O157:H7 str. EC4115 6967135 YP_002273523.1 CDS purH NC_011353.1 5117860 5119449 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(5117860..5119449) Escherichia coli O157:H7 str. EC4115 6967779 YP_002273524.1 CDS ECH74115_5482 NC_011353.1 5125193 5125636 R identified by match to protein family HMM PF00583; hypothetical protein complement(5125193..5125636) Escherichia coli O157:H7 str. EC4115 6972270 YP_002273525.1 CDS metA NC_011353.1 5125793 5126722 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 5125793..5126722 Escherichia coli O157:H7 str. EC4115 6967808 YP_002273526.1 CDS aceB NC_011353.1 5126991 5128592 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 5126991..5128592 Escherichia coli O157:H7 str. EC4115 6971340 YP_002273527.1 CDS aceA NC_011353.1 5128622 5129926 D identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346; isocitrate lyase 5128622..5129926 Escherichia coli O157:H7 str. EC4115 6971658 YP_002273528.1 CDS aceK NC_011353.1 5130110 5131846 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 5130110..5131846 Escherichia coli O157:H7 str. EC4115 6969403 YP_002273529.1 CDS ECH74115_5486 NC_011353.1 5131815 5134001 R identified by match to protein family HMM PF07906; ShET2 enterotoxin, N- region family complement(5131815..5134001) Escherichia coli O157:H7 str. EC4115 6968476 YP_002273530.1 CDS iclR NC_011353.1 5134318 5135142 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(5134318..5135142) Escherichia coli O157:H7 str. EC4115 6970433 YP_002273531.1 CDS metH NC_011353.1 5135342 5139025 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 5135342..5139025 Escherichia coli O157:H7 str. EC4115 6968177 YP_002273532.1 CDS pNaS NC_011353.1 5139245 5140876 D identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013; inorganic phosphate transporter sodium-dependent 5139245..5140876 Escherichia coli O157:H7 str. EC4115 6968994 YP_002273533.1 CDS pepE NC_011353.1 5140967 5141656 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(5140967..5141656) Escherichia coli O157:H7 str. EC4115 6969811 YP_002273534.1 CDS ECH74115_5493 NC_011353.1 5141927 5142070 D identified by glimmer; hypothetical protein 5141927..5142070 Escherichia coli O157:H7 str. EC4115 6969636 YP_002273535.1 CDS ECH74115_5492 NC_011353.1 5142039 5143268 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-sorbose 1-phosphate reductase complement(5142039..5143268) Escherichia coli O157:H7 str. EC4115 6970406 YP_002273536.1 CDS ECH74115_5494 NC_011353.1 5143320 5144144 R identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system mannose/fructose/sorbose family transporter subunit IID complement(5143320..5144144) Escherichia coli O157:H7 str. EC4115 6971023 YP_002273537.1 CDS ECH74115_5495 NC_011353.1 5144155 5144952 R identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822; PTS system mannose/fructose/sorbose family transporter subunit IIC complement(5144155..5144952) Escherichia coli O157:H7 str. EC4115 6969755 YP_002273538.1 CDS ECH74115_5497 NC_011353.1 5145512 5145919 R identified by match to protein family HMM PF03610; match to protein family HMM TIGR00824; PTS system mannose/fructose/sorbose family transporter subunit IIA complement(5145512..5145919) Escherichia coli O157:H7 str. EC4115 6969122 YP_002273539.1 CDS ECH74115_5498 NC_011353.1 5145929 5146735 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(5145929..5146735) Escherichia coli O157:H7 str. EC4115 6968326 YP_002273540.1 CDS sorC NC_011353.1 5146805 5147752 R identified by match to protein family HMM PF04198; sorbitol operon regulator SorC complement(5146805..5147752) Escherichia coli O157:H7 str. EC4115 6966636 YP_002273541.1 CDS rluF NC_011353.1 5148100 5148972 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 5148100..5148972 Escherichia coli O157:H7 str. EC4115 6967228 YP_002273542.1 CDS ECH74115_5501 NC_011353.1 5148973 5149245 R hypothetical protein complement(5148973..5149245) Escherichia coli O157:H7 str. EC4115 6971591 YP_002273543.1 CDS lysC NC_011353.1 5149498 5150847 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(5149498..5150847) Escherichia coli O157:H7 str. EC4115 6970937 YP_002273544.1 CDS pgi NC_011353.1 5151372 5153021 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 5151372..5153021 Escherichia coli O157:H7 str. EC4115 6970978 YP_002273545.1 CDS ECH74115_5505 NC_011353.1 5153534 5153776 D identified by glimmer; hypothetical protein 5153534..5153776 Escherichia coli O157:H7 str. EC4115 6970338 YP_002273546.1 CDS ECH74115_5506 NC_011353.1 5153890 5154528 D hypothetical protein 5153890..5154528 Escherichia coli O157:H7 str. EC4115 6966931 YP_002273547.1 CDS ECH74115_5507 NC_011353.1 5154600 5155262 D identified by match to protein family HMM PF06251; hypothetical protein 5154600..5155262 Escherichia coli O157:H7 str. EC4115 6971970 YP_002273548.1 CDS ECH74115_5508 NC_011353.1 5155262 5157358 D identified by match to protein family HMM PF06082; lipoprotein 5155262..5157358 Escherichia coli O157:H7 str. EC4115 6968442 YP_002273549.1 CDS ECH74115_5509 NC_011353.1 5157405 5157683 R hypothetical protein complement(5157405..5157683) Escherichia coli O157:H7 str. EC4115 6967889 YP_002273550.1 CDS ECH74115_5510 NC_011353.1 5157684 5157827 D identified by glimmer; hypothetical protein 5157684..5157827 Escherichia coli O157:H7 str. EC4115 6970179 YP_002273551.1 CDS psiE NC_011353.1 5157953 5158363 D identified by match to protein family HMM PF06146; phosphate-starvation-inducible protein PsiE 5157953..5158363 Escherichia coli O157:H7 str. EC4115 6969421 YP_002273552.1 CDS xylE NC_011353.1 5158407 5159882 R xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE complement(5158407..5159882) Escherichia coli O157:H7 str. EC4115 6970176 YP_002273553.1 CDS malG NC_011353.1 5160254 5161144 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(5160254..5161144) Escherichia coli O157:H7 str. EC4115 6969529 YP_002273554.1 CDS malF NC_011353.1 5161159 5162703 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(5161159..5162703) Escherichia coli O157:H7 str. EC4115 6969860 YP_002273555.1 CDS malE NC_011353.1 5162857 5164047 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(5162857..5164047) Escherichia coli O157:H7 str. EC4115 6972030 YP_002273556.1 CDS malK NC_011353.1 5164412 5165527 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 5164412..5165527 Escherichia coli O157:H7 str. EC4115 6971239 YP_002273557.1 CDS lamB NC_011353.1 5165599 5166939 D porin involved in the transport of maltose and maltodextrins; maltoporin 5165599..5166939 Escherichia coli O157:H7 str. EC4115 6971084 YP_002273558.1 CDS malM NC_011353.1 5167090 5168010 D identified by match to protein family HMM PF07148; maltose regulon periplasmic protein 5167090..5168010 Escherichia coli O157:H7 str. EC4115 6967421 YP_002273559.1 CDS ECH74115_5519 NC_011353.1 5168239 5169819 D in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 5168239..5169819 Escherichia coli O157:H7 str. EC4115 6967208 YP_002273560.1 CDS ubiC NC_011353.1 5170042 5170539 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 5170042..5170539 Escherichia coli O157:H7 str. EC4115 6969272 YP_002273561.1 CDS ubiA NC_011353.1 5170552 5171424 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 5170552..5171424 Escherichia coli O157:H7 str. EC4115 6968466 YP_002273562.1 CDS plsB NC_011353.1 5171579 5174002 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(5171579..5174002) Escherichia coli O157:H7 str. EC4115 6970485 YP_002273563.1 CDS dgkA NC_011353.1 5174173 5174541 D identified by match to protein family HMM PF01219; diacylglycerol kinase 5174173..5174541 Escherichia coli O157:H7 str. EC4115 6970439 YP_002273564.1 CDS lexA NC_011353.1 5174651 5175259 D Represses a number of genes involved in the response to DNA damage; LexA repressor 5174651..5175259 Escherichia coli O157:H7 str. EC4115 6967481 YP_002273565.1 CDS dinF NC_011353.1 5175332 5176657 D identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible SOS response protein 5175332..5176657 Escherichia coli O157:H7 str. EC4115 6972227 YP_002273566.1 CDS ECH74115_5526 NC_011353.1 5176773 5176982 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 5176773..5176982 Escherichia coli O157:H7 str. EC4115 6971592 YP_002273567.1 CDS zur NC_011353.1 5177024 5177539 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(5177024..5177539) Escherichia coli O157:H7 str. EC4115 6969023 YP_002273568.1 CDS ECH74115_5528 NC_011353.1 5177851 5178807 D hypothetical protein 5177851..5178807 Escherichia coli O157:H7 str. EC4115 6969650 YP_002273569.1 CDS ECH74115_5529 NC_011353.1 5179169 5179291 D TIM-barrel protein, YjbN family 5179169..5179291 Escherichia coli O157:H7 str. EC4115 6970647 YP_002273570.1 CDS ECH74115_5530 NC_011353.1 5179417 5179953 D hypothetical protein 5179417..5179953 Escherichia coli O157:H7 str. EC4115 6971267 YP_002273571.1 CDS ECH74115_5531 NC_011353.1 5180150 5180323 D hypothetical protein 5180150..5180323 Escherichia coli O157:H7 str. EC4115 6967280 YP_002273572.1 CDS ECH74115_5532 NC_011353.1 5180371 5180664 R hypothetical protein complement(5180371..5180664) Escherichia coli O157:H7 str. EC4115 6966658 YP_002273573.1 CDS ECH74115_5533 NC_011353.1 5180689 5180805 R endodeoxyribonuclease complement(5180689..5180805) Escherichia coli O157:H7 str. EC4115 6967427 YP_002273574.1 CDS ECH74115_5534 NC_011353.1 5180997 5181194 R hypothetical protein complement(5180997..5181194) Escherichia coli O157:H7 str. EC4115 6967441 YP_002273575.1 CDS ECH74115_5537 NC_011353.1 5181811 5182140 R Eae protein complement(5181811..5182140) Escherichia coli O157:H7 str. EC4115 6970375 YP_002273576.1 CDS ECH74115_5538 NC_011353.1 5182152 5182688 R hypothetical protein complement(5182152..5182688) Escherichia coli O157:H7 str. EC4115 6970489 YP_002273577.1 CDS ECH74115_5539 NC_011353.1 5182816 5183202 R hypothetical protein complement(5182816..5183202) Escherichia coli O157:H7 str. EC4115 6971601 YP_002273578.1 CDS ECH74115_5540 NC_011353.1 5183289 5183942 D fibronectin type III domain-containing protein 5183289..5183942 Escherichia coli O157:H7 str. EC4115 6971000 YP_002273579.1 CDS ECH74115_5541 NC_011353.1 5184010 5184609 D identified by match to protein family HMM PF06316; Ail/Lom family protein 5184010..5184609 Escherichia coli O157:H7 str. EC4115 6967332 YP_002273580.1 CDS ECH74115_5542 NC_011353.1 5184610 5184738 R hypothetical protein complement(5184610..5184738) Escherichia coli O157:H7 str. EC4115 6966548 YP_002273581.1 CDS ECH74115_5543 NC_011353.1 5184897 5185757 R hypothetical protein complement(5184897..5185757) Escherichia coli O157:H7 str. EC4115 6969096 YP_002273582.1 CDS ECH74115_5544 NC_011353.1 5185709 5185987 D identified by match to protein family HMM PF06820; tail fiber protein 5185709..5185987 Escherichia coli O157:H7 str. EC4115 6968218 YP_002273583.1 CDS ECH74115_5545 NC_011353.1 5185989 5186258 D identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 5185989..5186258 Escherichia coli O157:H7 str. EC4115 6967417 YP_002273584.1 CDS ECH74115_5546 NC_011353.1 5186370 5186942 D identified by match to protein family HMM PF06416; non-LEE-encoded effector NleG 5186370..5186942 Escherichia coli O157:H7 str. EC4115 6967769 YP_002273585.1 CDS ECH74115_5547 NC_011353.1 5187243 5187644 D identified by match to protein family HMM PF06416; hypothetical protein 5187243..5187644 Escherichia coli O157:H7 str. EC4115 6972155 YP_002273586.1 CDS ECH74115_5548 NC_011353.1 5187726 5188367 D identified by match to protein family HMM PF06416; hypothetical protein 5187726..5188367 Escherichia coli O157:H7 str. EC4115 6970074 YP_002273587.1 CDS ECH74115_5549 NC_011353.1 5188528 5188776 R identified by match to protein family HMM PF06183; hypothetical protein complement(5188528..5188776) Escherichia coli O157:H7 str. EC4115 6970525 YP_002273588.1 CDS ECH74115_5550 NC_011353.1 5188838 5189935 R identified by match to protein family HMM PF00589; phage integrase family protein complement(5188838..5189935) Escherichia coli O157:H7 str. EC4115 6968195 YP_002273589.1 CDS dusA NC_011353.1 5190024 5191061 D identified by match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 5190024..5191061 Escherichia coli O157:H7 str. EC4115 6968138 YP_002273590.1 CDS pspG NC_011353.1 5191195 5191437 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 5191195..5191437 Escherichia coli O157:H7 str. EC4115 6969017 YP_002273591.1 CDS qor NC_011353.1 5191603 5192586 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; quinone oxidoreductase complement(5191603..5192586) Escherichia coli O157:H7 str. EC4115 6966635 YP_002273592.1 CDS dnaB NC_011353.1 5192669 5194084 D unwinds double stranded DNA; replicative DNA helicase 5192669..5194084 Escherichia coli O157:H7 str. EC4115 6970399 YP_002273593.1 CDS alr NC_011353.1 5194137 5195216 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 5194137..5195216 Escherichia coli O157:H7 str. EC4115 6969044 YP_002273594.1 CDS tyrB NC_011353.1 5195427 5196662 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 5195427..5196662 Escherichia coli O157:H7 str. EC4115 6968947 YP_002273595.1 CDS aphA NC_011353.1 5197761 5198474 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 5197761..5198474 Escherichia coli O157:H7 str. EC4115 6971641 YP_002273596.1 CDS ECH74115_5559 NC_011353.1 5198585 5199001 D identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149; hypothetical protein 5198585..5199001 Escherichia coli O157:H7 str. EC4115 6971332 YP_002273597.1 CDS ECH74115_5560 NC_011353.1 5199005 5199361 D identified by match to protein family HMM PF04237; hypothetical protein 5199005..5199361 Escherichia coli O157:H7 str. EC4115 6970709 YP_002273598.1 CDS uvrA NC_011353.1 5199396 5202218 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(5199396..5202218) Escherichia coli O157:H7 str. EC4115 6970559 YP_002273599.1 CDS ssb NC_011353.1 5202473 5203009 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 5202473..5203009 Escherichia coli O157:H7 str. EC4115 6969843 YP_002273600.1 CDS ECH74115_5563 NC_011353.1 5203108 5203389 R hypothetical protein complement(5203108..5203389) Escherichia coli O157:H7 str. EC4115 6968088 YP_002273601.1 CDS ECH74115_5564 NC_011353.1 5203818 5205404 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 5203818..5205404 Escherichia coli O157:H7 str. EC4115 6970420 YP_002273602.1 CDS soxS NC_011353.1 5205407 5205730 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(5205407..5205730) Escherichia coli O157:H7 str. EC4115 6970813 YP_002273603.1 CDS soxR NC_011353.1 5205816 5206280 D identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950; redox-sensitive transcriptional activator SoxR 5205816..5206280 Escherichia coli O157:H7 str. EC4115 6969961 YP_002273604.1 CDS ECH74115_5568 NC_011353.1 5206826 5208175 D identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inorganic anion transporter sulfate permease (SulP) family 5206826..5208175 Escherichia coli O157:H7 str. EC4115 6970265 YP_002273605.1 CDS ECH74115_5569 NC_011353.1 5208153 5208269 D identified by glimmer; hypothetical protein 5208153..5208269 Escherichia coli O157:H7 str. EC4115 6969225 YP_002273606.1 CDS ECH74115_5570 NC_011353.1 5208326 5209975 D identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831; Na+/H+ antiporter 5208326..5209975 Escherichia coli O157:H7 str. EC4115 6968596 YP_002273607.1 CDS ECH74115_5571 NC_011353.1 5210129 5211421 R identified by match to protein family HMM PF00805; hypothetical protein complement(5210129..5211421) Escherichia coli O157:H7 str. EC4115 6971233 YP_002273608.1 CDS actP NC_011353.1 5211602 5213251 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(5211602..5213251) Escherichia coli O157:H7 str. EC4115 6967805 YP_002273609.1 CDS ECH74115_5573 NC_011353.1 5213248 5213562 R identified by match to protein family HMM PF04341; hypothetical protein complement(5213248..5213562) Escherichia coli O157:H7 str. EC4115 6969613 YP_002273610.1 CDS acsA NC_011353.1 5213763 5215721 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(5213763..5215721) Escherichia coli O157:H7 str. EC4115 6968380 YP_002273611.1 CDS nrfA NC_011353.1 5216114 5217550 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 5216114..5217550 Escherichia coli O157:H7 str. EC4115 6971056 YP_002273612.1 CDS nrfB NC_011353.1 5217595 5218161 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 5217595..5218161 Escherichia coli O157:H7 str. EC4115 6970409 YP_002273613.1 CDS nrfC NC_011353.1 5218158 5218829 D identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149; cytochrome c nitrite reductase, Fe-S protein 5218158..5218829 Escherichia coli O157:H7 str. EC4115 6967843 YP_002273614.1 CDS nrfD NC_011353.1 5218826 5219782 D identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148; nrfD protein 5218826..5219782 Escherichia coli O157:H7 str. EC4115 6967148 YP_002273615.1 CDS nrfE NC_011353.1 5219841 5221520 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 5219841..5221520 Escherichia coli O157:H7 str. EC4115 6969070 YP_002273616.1 CDS nrfF NC_011353.1 5221513 5221896 D identified by match to protein family HMM PF03918; match to protein family HMM TIGR03147; formate-dependent nitrite reductase complex subunit NrfF 5221513..5221896 Escherichia coli O157:H7 str. EC4115 6968428 YP_002273617.1 CDS nrfG NC_011353.1 5221893 5222489 D identified by match to protein family HMM PF00515; match to protein family HMM PF07719; formate-dependent nitrite reductase complex subunit NrfG 5221893..5222489 Escherichia coli O157:H7 str. EC4115 6969844 YP_002273618.1 CDS ECH74115_5582 NC_011353.1 5222623 5222751 R identified by glimmer; hypothetical protein complement(5222623..5222751) Escherichia coli O157:H7 str. EC4115 6969595 YP_002273619.1 CDS gltP NC_011353.1 5222831 5224144 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 5222831..5224144 Escherichia coli O157:H7 str. EC4115 6971600 YP_002273620.1 CDS ECH74115_5584 NC_011353.1 5224322 5225011 R identified by match to protein family HMM PF08238; Sel1 repeat protein complement(5224322..5225011) Escherichia coli O157:H7 str. EC4115 6971087 YP_002273621.1 CDS ECH74115_5588 NC_011353.1 5227450 5228916 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(5227450..5228916) Escherichia coli O157:H7 str. EC4115 6970334 YP_002273622.1 CDS mdtO NC_011353.1 5228913 5230964 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(5228913..5230964) Escherichia coli O157:H7 str. EC4115 6970976 YP_002273623.1 CDS mdtN NC_011353.1 5230964 5231995 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(5230964..5231995) Escherichia coli O157:H7 str. EC4115 6970640 YP_002273624.1 CDS ECH74115_5591 NC_011353.1 5232014 5232289 R hypothetical protein complement(5232014..5232289) Escherichia coli O157:H7 str. EC4115 6971437 YP_002273625.1 CDS ECH74115_5592 NC_011353.1 5232406 5232525 R identified by glimmer; hypothetical protein complement(5232406..5232525) Escherichia coli O157:H7 str. EC4115 6972222 YP_002273626.1 CDS ECH74115_5593 NC_011353.1 5232498 5234483 R identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein complement(5232498..5234483) Escherichia coli O157:H7 str. EC4115 6968710 YP_002273627.1 CDS ECH74115_5594 NC_011353.1 5234615 5234740 R identified by glimmer; hypothetical protein complement(5234615..5234740) Escherichia coli O157:H7 str. EC4115 6971589 YP_002273628.1 CDS ECH74115_5596 NC_011353.1 5234774 5235481 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; winged helix family two component transcriptional regulator 5234774..5235481 Escherichia coli O157:H7 str. EC4115 6966605 YP_002273629.1 CDS ECH74115_5595 NC_011353.1 5235478 5236479 R identified by match to protein family HMM PF00294; PfkB domain-containing protein complement(5235478..5236479) Escherichia coli O157:H7 str. EC4115 6966608 YP_002273630.1 CDS ECH74115_5597 NC_011353.1 5236476 5237336 R identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; hypothetical protein complement(5236476..5237336) Escherichia coli O157:H7 str. EC4115 6967420 YP_002273631.1 CDS ECH74115_5598 NC_011353.1 5237351 5238034 R identified by match to protein family HMM PF07385; hypothetical protein complement(5237351..5238034) Escherichia coli O157:H7 str. EC4115 6967458 YP_002273632.1 CDS ECH74115_5599 NC_011353.1 5238089 5239012 R identified by match to protein family HMM PF00532; periplasmic binding protein/LacI transcriptional regulator complement(5238089..5239012) Escherichia coli O157:H7 str. EC4115 6968301 YP_002273633.1 CDS ECH74115_5600 NC_011353.1 5239049 5240023 R identified by match to protein family HMM PF02653; ribose transport system permease RbsC complement(5239049..5240023) Escherichia coli O157:H7 str. EC4115 6968852 YP_002273634.1 CDS ECH74115_5601 NC_011353.1 5240020 5241540 R identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA complement(5240020..5241540) Escherichia coli O157:H7 str. EC4115 6972069 YP_002273635.1 CDS ECH74115_5602 NC_011353.1 5241539 5241652 D identified by glimmer; hypothetical protein 5241539..5241652 Escherichia coli O157:H7 str. EC4115 6969807 YP_002273636.1 CDS ECH74115_5603 NC_011353.1 5241654 5243924 D identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; hypothetical protein 5241654..5243924 Escherichia coli O157:H7 str. EC4115 6967248 YP_002273637.1 CDS phnP NC_011353.1 5244398 5245156 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(5244398..5245156) Escherichia coli O157:H7 str. EC4115 6970016 YP_002273638.1 CDS phnN NC_011353.1 5245580 5246137 R identified by match to protein family HMM TIGR02322; ribose 1,5-bisphosphokinase complement(5245580..5246137) Escherichia coli O157:H7 str. EC4115 6969148 YP_002273639.1 CDS phnM NC_011353.1 5246137 5247273 R identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318; phosphonate metabolism protein PhnM complement(5246137..5247273) Escherichia coli O157:H7 str. EC4115 6968144 YP_002273640.1 CDS phnL NC_011353.1 5247270 5247950 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR02324; phosphonate C-P lyase system protein PhnL complement(5247270..5247950) Escherichia coli O157:H7 str. EC4115 6967817 YP_002273641.1 CDS phnK NC_011353.1 5248061 5248819 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323; phosphonate C-P lyase system protein PhnK complement(5248061..5248819) Escherichia coli O157:H7 str. EC4115 6966916 YP_002273642.1 CDS phnJ NC_011353.1 5248816 5249661 R identified by match to protein family HMM PF06007; phosphonate metabolism protein PhnJ complement(5248816..5249661) Escherichia coli O157:H7 str. EC4115 6971710 YP_002273643.1 CDS phnI NC_011353.1 5249654 5250718 R identified by match to protein family HMM PF05861; phosphonate metabolism protein PhnI complement(5249654..5250718) Escherichia coli O157:H7 str. EC4115 6971050 YP_002273644.1 CDS phnH NC_011353.1 5250718 5251302 R identified by match to protein family HMM PF05845; match to protein family HMM TIGR03292; carbon-phosphorus lyase complex subunit complement(5250718..5251302) Escherichia coli O157:H7 str. EC4115 6969933 YP_002273645.1 CDS phnG NC_011353.1 5251299 5251751 R identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293; phosphonate C-P lyase system protein PhnG complement(5251299..5251751) Escherichia coli O157:H7 str. EC4115 6967206 YP_002273646.1 CDS phnF NC_011353.1 5251752 5252477 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(5251752..5252477) Escherichia coli O157:H7 str. EC4115 6971974 YP_002273647.1 CDS phnE NC_011353.1 5252498 5253277 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097; phosphonate ABC transporter permease complement(5252498..5253277) Escherichia coli O157:H7 str. EC4115 6968762 YP_002273648.1 CDS ECH74115_5618 NC_011353.1 5253272 5253421 D identified by glimmer; hypothetical protein 5253272..5253421 Escherichia coli O157:H7 str. EC4115 6968637 YP_002273649.1 CDS phnD NC_011353.1 5253383 5254399 R identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431; phosphonate ABC transporter periplasmic phosphonate-binding protein complement(5253383..5254399) Escherichia coli O157:H7 str. EC4115 6969384 YP_002273650.1 CDS phnC NC_011353.1 5254424 5255212 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315; phosphonate/organophosphate ester transporter subunit complement(5254424..5255212) Escherichia coli O157:H7 str. EC4115 6970192 YP_002273651.1 CDS ECH74115_5620 NC_011353.1 5255345 5255788 R identified by match to protein family HMM PF00903; match to protein family HMM PF06983; hypothetical protein complement(5255345..5255788) Escherichia coli O157:H7 str. EC4115 6970621 YP_002273652.1 CDS phnA NC_011353.1 5256047 5256460 R identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA complement(5256047..5256460) Escherichia coli O157:H7 str. EC4115 6970382 YP_002273653.1 CDS ECH74115_5622 NC_011353.1 5256784 5259012 D hypothetical protein 5256784..5259012 Escherichia coli O157:H7 str. EC4115 6972247 YP_002273654.1 CDS ECH74115_5623 NC_011353.1 5259009 5259887 D hypothetical protein 5259009..5259887 Escherichia coli O157:H7 str. EC4115 6971428 YP_002273655.1 CDS proP NC_011353.1 5260151 5261653 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883; proline/glycine betaine transporter 5260151..5261653 Escherichia coli O157:H7 str. EC4115 6969606 YP_002273656.1 CDS basS NC_011353.1 5261830 5262930 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein BasS/PmrB complement(5261830..5262930) Escherichia coli O157:H7 str. EC4115 6972036 YP_002273657.1 CDS basR NC_011353.1 5262931 5263599 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(5262931..5263599) Escherichia coli O157:H7 str. EC4115 6969031 YP_002273658.1 CDS ECH74115_5627 NC_011353.1 5263596 5265239 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(5263596..5265239) Escherichia coli O157:H7 str. EC4115 6968577 YP_002273659.1 CDS adiC NC_011353.1 5265343 5266680 R identified by match to protein family HMM PF00324; arginine:agmatin antiporter complement(5265343..5266680) Escherichia coli O157:H7 str. EC4115 6967767 YP_002273660.1 CDS adiY NC_011353.1 5266817 5267578 R identified by match to protein family HMM PF00165; transcriptional regulator AdiY complement(5266817..5267578) Escherichia coli O157:H7 str. EC4115 6967144 YP_002273661.1 CDS ECH74115_5630 NC_011353.1 5267535 5267672 R identified by glimmer; hypothetical protein complement(5267535..5267672) Escherichia coli O157:H7 str. EC4115 6967484 YP_002273662.1 CDS adiA NC_011353.1 5267903 5270173 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; biodegradative arginine decarboxylase complement(5267903..5270173) Escherichia coli O157:H7 str. EC4115 6966860 YP_002273663.1 CDS melR NC_011353.1 5270369 5271277 R identified by match to protein family HMM PF00165; DNA-binding transcriptional regulator MelR complement(5270369..5271277) Escherichia coli O157:H7 str. EC4115 6971964 YP_002273664.1 CDS melA NC_011353.1 5271560 5272915 D identified by match to protein family HMM PF02056; alpha-galactosidase 5271560..5272915 Escherichia coli O157:H7 str. EC4115 6971343 YP_002273665.1 CDS melB NC_011353.1 5272994 5274439 D identified by match to protein family HMM TIGR00792; melibiose:sodium symporter 5272994..5274439 Escherichia coli O157:H7 str. EC4115 6971552 YP_002273666.1 CDS ECH74115_5635 NC_011353.1 5274578 5275207 R hypothetical protein complement(5274578..5275207) Escherichia coli O157:H7 str. EC4115 6967081 YP_002273667.1 CDS fumB NC_011353.1 5275330 5276976 R identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase complement(5275330..5276976) Escherichia coli O157:H7 str. EC4115 6971511 YP_002273668.1 CDS dcuB NC_011353.1 5277054 5278394 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(5277054..5278394) Escherichia coli O157:H7 str. EC4115 6971984 YP_002273669.1 CDS dcuR NC_011353.1 5278965 5279684 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(5278965..5279684) Escherichia coli O157:H7 str. EC4115 6969757 YP_002273670.1 CDS dcuS NC_011353.1 5279681 5281312 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(5279681..5281312) Escherichia coli O157:H7 str. EC4115 6969710 YP_002273671.1 CDS ECH74115_5640 NC_011353.1 5281304 5281438 D identified by glimmer; hypothetical protein 5281304..5281438 Escherichia coli O157:H7 str. EC4115 6968298 YP_002273672.1 CDS ECH74115_5641 NC_011353.1 5281493 5281723 D identified by match to protein family HMM PF06902; hypothetical protein 5281493..5281723 Escherichia coli O157:H7 str. EC4115 6968933 YP_002273673.1 CDS ECH74115_5642 NC_011353.1 5281735 5282007 D hypothetical protein 5281735..5282007 Escherichia coli O157:H7 str. EC4115 6966685 YP_002273674.1 CDS ECH74115_5643 NC_011353.1 5282324 5282530 D identified by glimmer; hypothetical protein 5282324..5282530 Escherichia coli O157:H7 str. EC4115 6967873 YP_002273675.1 CDS ECH74115_5644 NC_011353.1 5282558 5282731 D hypothetical protein 5282558..5282731 Escherichia coli O157:H7 str. EC4115 6970682 YP_002273676.1 CDS lysU NC_011353.1 5282850 5284367 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(5282850..5284367) Escherichia coli O157:H7 str. EC4115 6970994 YP_002273677.1 CDS ECH74115_5646 NC_011353.1 5284604 5286061 R identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter complement(5284604..5286061) Escherichia coli O157:H7 str. EC4115 6971862 YP_002273678.1 CDS ldcC2 NC_011353.1 5286120 5288267 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase, constitutive complement(5286120..5288267) Escherichia coli O157:H7 str. EC4115 6969386 YP_002273679.1 CDS cadB NC_011353.1 5288347 5289681 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(5288347..5289681) Escherichia coli O157:H7 str. EC4115 6970261 YP_002273680.1 CDS cadC NC_011353.1 5290047 5291585 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(5290047..5291585) Escherichia coli O157:H7 str. EC4115 6968639 YP_002273681.1 CDS ECH74115_5651 NC_011353.1 5292384 5292959 R identified by match to protein family HMM PF00440; transcriptional regulator complement(5292384..5292959) Escherichia coli O157:H7 str. EC4115 6972424 YP_002273682.1 CDS dipZ NC_011353.1 5292996 5294693 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(5292996..5294693) Escherichia coli O157:H7 str. EC4115 6967013 YP_002273683.1 CDS cutA NC_011353.1 5294669 5295007 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(5294669..5295007) Escherichia coli O157:H7 str. EC4115 6967772 YP_002273684.1 CDS dcuA NC_011353.1 5295123 5296424 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(5295123..5296424) Escherichia coli O157:H7 str. EC4115 6971959 YP_002273685.1 CDS aspA NC_011353.1 5296542 5297978 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(5296542..5297978) Escherichia coli O157:H7 str. EC4115 6968656 YP_002273686.1 CDS ECH74115_5657 NC_011353.1 5298612 5300063 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH complement(5298612..5300063) Escherichia coli O157:H7 str. EC4115 6969605 YP_002273687.1 CDS groES NC_011353.1 5300339 5300632 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 5300339..5300632 Escherichia coli O157:H7 str. EC4115 6972043 YP_002273688.1 CDS groEL NC_011353.1 5300676 5302322 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 5300676..5302322 Escherichia coli O157:H7 str. EC4115 6971053 YP_002273689.1 CDS ECH74115_5660 NC_011353.1 5302460 5302813 D lipoprotein 5302460..5302813 Escherichia coli O157:H7 str. EC4115 6969244 YP_002273690.1 CDS ECH74115_5661 NC_011353.1 5303006 5303875 R hypothetical protein complement(5303006..5303875) Escherichia coli O157:H7 str. EC4115 6968607 YP_002273691.1 CDS ECH74115_5662 NC_011353.1 5304110 5305138 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238; KamA family protein complement(5304110..5305138) Escherichia coli O157:H7 str. EC4115 6967652 YP_002273692.1 CDS efp NC_011353.1 5305180 5305746 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 5305180..5305746 Escherichia coli O157:H7 str. EC4115 6967031 YP_002273693.1 CDS ecnB2 NC_011353.1 5305798 5305923 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 5305798..5305923 Escherichia coli O157:H7 str. EC4115 6971741 YP_002273694.1 CDS ecnB1 NC_011353.1 5306034 5306180 D identified by match to protein family HMM PF08085; entericidin B membrane lipoprotein 5306034..5306180 Escherichia coli O157:H7 str. EC4115 6969454 YP_002273695.1 CDS sugE NC_011353.1 5306356 5306673 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 5306356..5306673 Escherichia coli O157:H7 str. EC4115 6971561 YP_002273696.1 CDS blc NC_011353.1 5306670 5307203 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(5306670..5307203) Escherichia coli O157:H7 str. EC4115 6967834 YP_002273697.1 CDS ampC NC_011353.1 5307291 5308424 R identified by match to protein family HMM PF00144; beta-lactamase complement(5307291..5308424) Escherichia coli O157:H7 str. EC4115 6970952 YP_002273698.1 CDS frdD NC_011353.1 5308487 5308846 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(5308487..5308846) Escherichia coli O157:H7 str. EC4115 6966702 YP_002273699.1 CDS frdC NC_011353.1 5308857 5309252 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(5308857..5309252) Escherichia coli O157:H7 str. EC4115 6969221 YP_002273700.1 CDS frdB NC_011353.1 5309263 5309997 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(5309263..5309997) Escherichia coli O157:H7 str. EC4115 6968582 YP_002273701.1 CDS frdA NC_011353.1 5309990 5311798 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(5309990..5311798) Escherichia coli O157:H7 str. EC4115 6970870 YP_002273702.1 CDS genX NC_011353.1 5312123 5313100 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 5312123..5313100 Escherichia coli O157:H7 str. EC4115 6970239 YP_002273703.1 CDS ECH74115_5674 NC_011353.1 5313277 5314821 D identified by match to protein family HMM PF00324; amino acid permease family protein 5313277..5314821 Escherichia coli O157:H7 str. EC4115 6966796 YP_002273704.1 CDS ECH74115_5675 NC_011353.1 5314972 5318295 R identified by match to protein family HMM PF00924; hypothetical protein complement(5314972..5318295) Escherichia coli O157:H7 str. EC4115 6967429 YP_002273705.1 CDS psd NC_011353.1 5318317 5319285 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(5318317..5319285) Escherichia coli O157:H7 str. EC4115 6971611 YP_002273706.1 CDS rsgA NC_011353.1 5319382 5320434 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(5319382..5320434) Escherichia coli O157:H7 str. EC4115 6970971 YP_002273707.1 CDS orn NC_011353.1 5320529 5321074 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 5320529..5321074 Escherichia coli O157:H7 str. EC4115 6970328 YP_002273708.1 CDS ECH74115_5682 NC_011353.1 5321853 5322992 R identified by match to protein family HMM PF08331; match to protein family HMM TIGR00276; iron-sulfur cluster binding protein complement(5321853..5322992) Escherichia coli O157:H7 str. EC4115 6972411 YP_002273709.1 CDS ECH74115_5683 NC_011353.1 5323006 5324538 D identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; hypothetical protein 5323006..5324538 Escherichia coli O157:H7 str. EC4115 6967054 YP_002273710.1 CDS ECH74115_5684 NC_011353.1 5324513 5324971 D possibly involved in cell wall synthesis; ATPase 5324513..5324971 Escherichia coli O157:H7 str. EC4115 6969110 YP_002273711.1 CDS amiB NC_011353.1 5324990 5326327 D identified by match to protein family HMM PF01520; N-acetylmuramoyl-l-alanine amidase II 5324990..5326327 Escherichia coli O157:H7 str. EC4115 6971360 YP_002273712.1 CDS mutL NC_011353.1 5326337 5328184 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 5326337..5328184 Escherichia coli O157:H7 str. EC4115 6967356 YP_002273713.1 CDS miaA NC_011353.1 5328177 5329127 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 5328177..5329127 Escherichia coli O157:H7 str. EC4115 6969441 YP_002273714.1 CDS hfq NC_011353.1 5329213 5329521 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 5329213..5329521 Escherichia coli O157:H7 str. EC4115 6971801 YP_002273715.1 CDS hflX NC_011353.1 5329598 5330878 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 5329598..5330878 Escherichia coli O157:H7 str. EC4115 6971907 YP_002273716.1 CDS hflK NC_011353.1 5330964 5332223 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 5330964..5332223 Escherichia coli O157:H7 str. EC4115 6967496 YP_002273717.1 CDS hflC NC_011353.1 5332226 5333230 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 5332226..5333230 Escherichia coli O157:H7 str. EC4115 6970953 YP_002273718.1 CDS ECH74115_5692 NC_011353.1 5333312 5333509 D hypothetical protein 5333312..5333509 Escherichia coli O157:H7 str. EC4115 6968727 YP_002273719.1 CDS purA NC_011353.1 5333613 5334911 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5333613..5334911 Escherichia coli O157:H7 str. EC4115 6967189 YP_002273720.1 CDS nsrR NC_011353.1 5335116 5335541 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 5335116..5335541 Escherichia coli O157:H7 str. EC4115 6970685 YP_002273721.1 CDS rnr NC_011353.1 5335580 5338021 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 5335580..5338021 Escherichia coli O157:H7 str. EC4115 6968367 YP_002273722.1 CDS ECH74115_5696 NC_011353.1 5338202 5338933 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 5338202..5338933 Escherichia coli O157:H7 str. EC4115 6969706 YP_002273723.1 CDS ECH74115_5697 NC_011353.1 5339060 5339461 D hypothetical protein 5339060..5339461 Escherichia coli O157:H7 str. EC4115 6970344 YP_002273724.1 CDS ECH74115_5698 NC_011353.1 5339480 5340178 D identified by match to protein family HMM PF04012; PspA/IM30 family protein 5339480..5340178 Escherichia coli O157:H7 str. EC4115 6968383 YP_002273725.1 CDS ECH74115_5699 NC_011353.1 5340229 5340888 D hypothetical protein 5340229..5340888 Escherichia coli O157:H7 str. EC4115 6969175 YP_002273726.1 CDS ECH74115_5700 NC_011353.1 5340906 5341304 D identified by match to protein family HMM PF03994; inner membrane protein 5340906..5341304 Escherichia coli O157:H7 str. EC4115 6969369 YP_002273727.1 CDS ECH74115_5701 NC_011353.1 5341314 5341952 D identified by match to protein family HMM PF06693; hypothetical protein 5341314..5341952 Escherichia coli O157:H7 str. EC4115 6966935 YP_002273728.1 CDS ECH74115_5702 NC_011353.1 5341955 5343118 D identified by match to protein family HMM PF03738; glutathionylspermidine synthase 5341955..5343118 Escherichia coli O157:H7 str. EC4115 6967355 YP_002273729.1 CDS ECH74115_5703 NC_011353.1 5343202 5344827 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 5343202..5344827 Escherichia coli O157:H7 str. EC4115 6971392 YP_002273730.1 CDS ECH74115_5704 NC_011353.1 5344944 5345231 R identified by match to protein family HMM PF07338; hypothetical protein complement(5344944..5345231) Escherichia coli O157:H7 str. EC4115 6970852 YP_002273731.1 CDS ECH74115_5705 NC_011353.1 5345368 5345697 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(5345368..5345697) Escherichia coli O157:H7 str. EC4115 6969846 YP_002273732.1 CDS ECH74115_5707 NC_011353.1 5345879 5346628 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 5345879..5346628 Escherichia coli O157:H7 str. EC4115 6969436 YP_002273733.1 CDS ulaR NC_011353.1 5346625 5347380 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(5346625..5347380) Escherichia coli O157:H7 str. EC4115 6969702 YP_002273734.1 CDS ECH74115_5708 NC_011353.1 5347488 5348552 R L-ascorbate 6-phosphate lactonase complement(5347488..5348552) Escherichia coli O157:H7 str. EC4115 6970414 YP_002273735.1 CDS ulaA NC_011353.1 5348907 5350304 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 5348907..5350304 Escherichia coli O157:H7 str. EC4115 6970357 YP_002273736.1 CDS ulaB NC_011353.1 5350320 5350625 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 5350320..5350625 Escherichia coli O157:H7 str. EC4115 6970362 YP_002273737.1 CDS ulaC NC_011353.1 5350635 5351099 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 5350635..5351099 Escherichia coli O157:H7 str. EC4115 6968446 YP_002273738.1 CDS ulaD NC_011353.1 5351113 5351763 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 5351113..5351763 Escherichia coli O157:H7 str. EC4115 6969091 YP_002273739.1 CDS ulaE NC_011353.1 5351773 5352627 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 5351773..5352627 Escherichia coli O157:H7 str. EC4115 6967184 YP_002273740.1 CDS sgaE NC_011353.1 5352627 5353313 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 5352627..5353313 Escherichia coli O157:H7 str. EC4115 6967180 YP_002273741.1 CDS ECH74115_5715 NC_011353.1 5353442 5353717 R identified by match to protein family HMM PF07338; hypothetical protein complement(5353442..5353717) Escherichia coli O157:H7 str. EC4115 6967785 YP_002273742.1 CDS rpsF NC_011353.1 5354044 5354439 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 5354044..5354439 Escherichia coli O157:H7 str. EC4115 6971800 YP_002273743.1 CDS rpsR NC_011353.1 5354765 5354992 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5354765..5354992 Escherichia coli O157:H7 str. EC4115 6969410 YP_002273744.1 CDS rplI NC_011353.1 5355034 5355483 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 5355034..5355483 Escherichia coli O157:H7 str. EC4115 6971734 YP_002273745.1 CDS ECH74115_5719 NC_011353.1 5355554 5356348 R hypothetical protein complement(5355554..5356348) Escherichia coli O157:H7 str. EC4115 6972046 YP_002273746.1 CDS ECH74115_5720 NC_011353.1 5356791 5357117 D hypothetical protein 5356791..5357117 Escherichia coli O157:H7 str. EC4115 6970121 YP_002273747.1 CDS ECH74115_5721 NC_011353.1 5357286 5357432 D identified by glimmer; hypothetical protein 5357286..5357432 Escherichia coli O157:H7 str. EC4115 6969712 YP_002273748.1 CDS ECH74115_5722 NC_011353.1 5357410 5358618 D identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; transposase, IS605 orfB family 5357410..5358618 Escherichia coli O157:H7 str. EC4115 6967121 YP_002273749.1 CDS ECH74115_5723 NC_011353.1 5358753 5359391 R identified by match to protein family HMM PF04225; match to protein family HMM PF08525; opacity-associated family protein complement(5358753..5359391) Escherichia coli O157:H7 str. EC4115 6968691 YP_002273750.1 CDS fklB NC_011353.1 5359609 5360229 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 5359609..5360229 Escherichia coli O157:H7 str. EC4115 6971242 YP_002273751.1 CDS cycA NC_011353.1 5360538 5361950 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 5360538..5361950 Escherichia coli O157:H7 str. EC4115 6967856 YP_002273752.1 CDS ECH74115_5726 NC_011353.1 5361995 5362657 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(5361995..5362657) Escherichia coli O157:H7 str. EC4115 6970569 YP_002273753.1 CDS ECH74115_5727 NC_011353.1 5362765 5363730 R identified by match to protein family HMM PF00892; hypothetical protein complement(5362765..5363730) Escherichia coli O157:H7 str. EC4115 6969786 YP_002273754.1 CDS ECH74115_5728 NC_011353.1 5363838 5364698 R identified by match to protein family HMM PF01073; match to protein family HMM PF02254; match to protein family HMM PF05368; NmrA family protein complement(5363838..5364698) Escherichia coli O157:H7 str. EC4115 6970929 YP_002273755.1 CDS ECH74115_5729 NC_011353.1 5364787 5365167 D identified by match to protein family HMM PF01638; transcriptional regulator 5364787..5365167 Escherichia coli O157:H7 str. EC4115 6971404 YP_002273756.1 CDS cpdB NC_011353.1 5365285 5367228 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(5365285..5367228) Escherichia coli O157:H7 str. EC4115 6969231 YP_002273757.1 CDS cysQ NC_011353.1 5367418 5368158 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 5367418..5368158 Escherichia coli O157:H7 str. EC4115 6967488 YP_002273758.1 CDS ECH74115_5732 NC_011353.1 5368370 5369308 D hypothetical protein 5368370..5369308 Escherichia coli O157:H7 str. EC4115 6968295 YP_002273759.1 CDS ECH74115_5733 NC_011353.1 5369371 5369925 R identified by match to protein family HMM PF09695; match to protein family HMM TIGR01626; hypothetical protein complement(5369371..5369925) Escherichia coli O157:H7 str. EC4115 6968922 YP_002273760.1 CDS ECH74115_5734 NC_011353.1 5370250 5370456 D identified by match to protein family HMM PF06526; hypothetical protein 5370250..5370456 Escherichia coli O157:H7 str. EC4115 6969970 YP_002273761.1 CDS ECH74115_5735 NC_011353.1 5370535 5371878 R identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; transporter complement(5370535..5371878) Escherichia coli O157:H7 str. EC4115 6970610 YP_002273762.1 CDS msrA NC_011353.1 5372201 5372839 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(5372201..5372839) Escherichia coli O157:H7 str. EC4115 6971222 YP_002273763.1 CDS ECH74115_5737 NC_011353.1 5372947 5373075 D identified by glimmer; hypothetical protein 5372947..5373075 Escherichia coli O157:H7 str. EC4115 6969660 YP_002273764.1 CDS ECH74115_5738 NC_011353.1 5373045 5374778 D identified by match to protein family HMM PF01103; match to protein family HMM PF07244; OMP85 family outer membrane protein 5373045..5374778 Escherichia coli O157:H7 str. EC4115 6969797 YP_002273765.1 CDS ECH74115_5739 NC_011353.1 5374775 5378554 D identified by match to protein family HMM PF04357; hypothetical protein 5374775..5378554 Escherichia coli O157:H7 str. EC4115 6969344 YP_002273766.1 CDS ECH74115_5740 NC_011353.1 5378557 5378898 D identified by match to protein family HMM PF06094; hypothetical protein 5378557..5378898 Escherichia coli O157:H7 str. EC4115 6970908 YP_002273767.1 CDS chpS NC_011353.1 5379104 5379361 D part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 5379104..5379361 Escherichia coli O157:H7 str. EC4115 6970266 YP_002273768.1 CDS chpB NC_011353.1 5379355 5379705 D toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 5379355..5379705 Escherichia coli O157:H7 str. EC4115 6971440 YP_002273769.1 CDS ppa NC_011353.1 5379785 5380315 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(5379785..5380315) Escherichia coli O157:H7 str. EC4115 6970972 YP_002273770.1 CDS ECH74115_5744 NC_011353.1 5380314 5380454 D identified by glimmer; hypothetical protein 5380314..5380454 Escherichia coli O157:H7 str. EC4115 6966906 YP_002273771.1 CDS ECH74115_5745 NC_011353.1 5380625 5381581 D identified by match to protein family HMM PF00532; sugar ABC transporter substrate-binding protein 5380625..5381581 Escherichia coli O157:H7 str. EC4115 6972200 YP_002273772.1 CDS ECH74115_5749 NC_011353.1 5383237 5384259 D overlaps another CDS with the same product name; identified by match to protein family HMM PF02653; sugar ABC transporter permease 5383237..5384259 Escherichia coli O157:H7 str. EC4115 6968285 YP_002273773.1 CDS ECH74115_5750 NC_011353.1 5384246 5385241 D membrane component of a sugar ABC transporter system; inner membrane ABC transporter permease YjfF 5384246..5385241 Escherichia coli O157:H7 str. EC4115 6971311 YP_002273774.1 CDS fbp NC_011353.1 5385274 5386272 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(5385274..5386272) Escherichia coli O157:H7 str. EC4115 6970220 YP_002273775.1 CDS mpl NC_011353.1 5386448 5387821 D identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 5386448..5387821 Escherichia coli O157:H7 str. EC4115 6966736 YP_002273776.1 CDS yjgA NC_011353.1 5387977 5388528 R identified by match to protein family HMM PF04751; hypothetical protein complement(5387977..5388528) Escherichia coli O157:H7 str. EC4115 6972006 YP_002273777.1 CDS pmbA NC_011353.1 5388634 5389974 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 5388634..5389974 Escherichia coli O157:H7 str. EC4115 6971730 YP_002273778.1 CDS cybC NC_011353.1 5390158 5390544 D identified by match to protein family HMM PF07361; soluble cytochrome b562 5390158..5390544 Escherichia coli O157:H7 str. EC4115 6966990 YP_002273779.1 CDS nrdG NC_011353.1 5390589 5391053 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(5390589..5391053) Escherichia coli O157:H7 str. EC4115 6967319 YP_002273780.1 CDS ECH74115_5757 NC_011353.1 5391042 5391236 D hypothetical protein 5391042..5391236 Escherichia coli O157:H7 str. EC4115 6968222 YP_002273781.1 CDS nrdD NC_011353.1 5391243 5393381 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(5391243..5393381) Escherichia coli O157:H7 str. EC4115 6967075 YP_002273782.1 CDS ECH74115_5759 NC_011353.1 5393421 5393543 D identified by glimmer; hypothetical protein 5393421..5393543 Escherichia coli O157:H7 str. EC4115 6966683 YP_002273783.1 CDS ECH74115_5760 NC_011353.1 5393627 5393803 R identified by glimmer; hypothetical protein complement(5393627..5393803) Escherichia coli O157:H7 str. EC4115 6971192 YP_002273784.1 CDS treC NC_011353.1 5393775 5395430 R identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; trehalose-6-phosphate hydrolase complement(5393775..5395430) Escherichia coli O157:H7 str. EC4115 6970542 YP_002273785.1 CDS treB NC_011353.1 5395480 5396901 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(5395480..5396901) Escherichia coli O157:H7 str. EC4115 6971206 YP_002273786.1 CDS treR NC_011353.1 5397020 5397967 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(5397020..5397967) Escherichia coli O157:H7 str. EC4115 6970790 YP_002273787.1 CDS mgtA NC_011353.1 5398346 5401042 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 5398346..5401042 Escherichia coli O157:H7 str. EC4115 6969952 YP_002273788.1 CDS ECH74115_5765 NC_011353.1 5401248 5401673 R identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP complement(5401248..5401673) Escherichia coli O157:H7 str. EC4115 6968798 YP_002273789.1 CDS pyrI NC_011353.1 5401707 5402168 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit complement(5401707..5402168) Escherichia coli O157:H7 str. EC4115 6967976 YP_002273790.1 CDS pyrB NC_011353.1 5402181 5403116 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(5402181..5403116) Escherichia coli O157:H7 str. EC4115 6967526 YP_002273791.1 CDS ECH74115_5768 NC_011353.1 5403293 5403430 R identified by glimmer; hypothetical protein complement(5403293..5403430) Escherichia coli O157:H7 str. EC4115 6969548 YP_002273792.1 CDS ECH74115_5769 NC_011353.1 5403535 5403930 R identified by match to protein family HMM PF01042; endoribonuclease L-PSP family protein complement(5403535..5403930) Escherichia coli O157:H7 str. EC4115 6968723 YP_002273793.1 CDS ECH74115_5770 NC_011353.1 5403888 5404046 D identified by glimmer; hypothetical protein 5403888..5404046 Escherichia coli O157:H7 str. EC4115 6968300 YP_002273794.1 CDS ECH74115_5771 NC_011353.1 5404061 5404774 R identified by match to protein family HMM PF00106; oxidoreductase complement(5404061..5404774) Escherichia coli O157:H7 str. EC4115 6967498 YP_002273795.1 CDS ECH74115_5772 NC_011353.1 5404845 5405438 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5404845..5405438 Escherichia coli O157:H7 str. EC4115 6972045 YP_002273796.1 CDS ECH74115_5773 NC_011353.1 5405583 5406035 D identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 5405583..5406035 Escherichia coli O157:H7 str. EC4115 6971215 YP_002273797.1 CDS ECH74115_5774 NC_011353.1 5406158 5407894 D hypothetical protein 5406158..5407894 Escherichia coli O157:H7 str. EC4115 6970759 YP_002273798.1 CDS argF NC_011353.1 5407951 5408955 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(5407951..5408955) Escherichia coli O157:H7 str. EC4115 6969936 YP_002273799.1 CDS ECH74115_5776 NC_011353.1 5409117 5409533 D identified by match to protein family HMM PF06877; hypothetical protein 5409117..5409533 Escherichia coli O157:H7 str. EC4115 6969475 YP_002273800.1 CDS ECH74115_5777 NC_011353.1 5409579 5410082 R identified by match to protein family HMM PF00583; GNAT family acetyltransferase complement(5409579..5410082) Escherichia coli O157:H7 str. EC4115 6969013 YP_002273801.1 CDS ECH74115_5778 NC_011353.1 5410248 5411471 D identified by match to protein family HMM PF05987; hypothetical protein 5410248..5411471 Escherichia coli O157:H7 str. EC4115 6967585 YP_002273802.1 CDS valS NC_011353.1 5411526 5414381 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(5411526..5414381) Escherichia coli O157:H7 str. EC4115 6970919 YP_002273803.1 CDS holC NC_011353.1 5414381 5414824 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(5414381..5414824) Escherichia coli O157:H7 str. EC4115 6971359 YP_002273804.1 CDS pepA NC_011353.1 5415178 5416689 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(5415178..5416689) Escherichia coli O157:H7 str. EC4115 6972163 YP_002273805.1 CDS ECH74115_5782 NC_011353.1 5416914 5417042 R identified by glimmer; hypothetical protein complement(5416914..5417042) Escherichia coli O157:H7 str. EC4115 6968432 YP_002273806.1 CDS ECH74115_5783 NC_011353.1 5416956 5418056 D identified by match to protein family HMM PF03739; permease 5416956..5418056 Escherichia coli O157:H7 str. EC4115 6969154 YP_002273807.1 CDS ECH74115_5784 NC_011353.1 5418056 5419138 D identified by match to protein family HMM PF03739; permease 5418056..5419138 Escherichia coli O157:H7 str. EC4115 6966713 YP_002273808.1 CDS ECH74115_5785 NC_011353.1 5419299 5420801 R identified by match to protein family HMM PF05872; hypothetical protein complement(5419299..5420801) Escherichia coli O157:H7 str. EC4115 6967857 YP_002273809.1 CDS ECH74115_5786 NC_011353.1 5420931 5421950 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family complement(5420931..5421950) Escherichia coli O157:H7 str. EC4115 6971161 YP_002273810.1 CDS ECH74115_5787 NC_011353.1 5422025 5422228 R hypothetical protein complement(5422025..5422228) Escherichia coli O157:H7 str. EC4115 6971576 YP_002273811.1 CDS ECH74115_5789 NC_011353.1 5422570 5424240 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 5422570..5424240 Escherichia coli O157:H7 str. EC4115 6972350 YP_002273812.1 CDS ECH74115_5790 NC_011353.1 5424866 5425198 R identified by match to protein family HMM PF07978; nipsnap family protein complement(5424866..5425198) Escherichia coli O157:H7 str. EC4115 6971482 YP_002273813.1 CDS ECH74115_5791 NC_011353.1 5426202 5426669 R identified by match to protein family HMM PF07799; hypothetical protein complement(5426202..5426669) Escherichia coli O157:H7 str. EC4115 6971083 YP_002273814.1 CDS ECH74115_5792 NC_011353.1 5426793 5427431 D identified by match to protein family HMM PF00239; resolvase TnpR 5426793..5427431 Escherichia coli O157:H7 str. EC4115 6969900 YP_002273815.1 CDS ECH74115_5793 NC_011353.1 5427630 5428946 R hypothetical protein complement(5427630..5428946) Escherichia coli O157:H7 str. EC4115 6969515 YP_002273816.1 CDS ECH74115_5794 NC_011353.1 5429098 5429871 R hypothetical protein complement(5429098..5429871) Escherichia coli O157:H7 str. EC4115 6970118 YP_002273817.1 CDS ECH74115_5795 NC_011353.1 5429988 5430452 D identified by match to protein family HMM PF01381; transcriptional regulator 5429988..5430452 Escherichia coli O157:H7 str. EC4115 6966781 YP_002273818.1 CDS ECH74115_5796 NC_011353.1 5430608 5430721 D identified by glimmer; hypothetical protein 5430608..5430721 Escherichia coli O157:H7 str. EC4115 6967566 YP_002273819.1 CDS ECH74115_5797 NC_011353.1 5431168 5431995 D prophage P4 integrase 5431168..5431995 Escherichia coli O157:H7 str. EC4115 6971130 YP_002273820.1 CDS ECH74115_5799 NC_011353.1 5432455 5433306 R HNH nuclease complement(5432455..5433306) Escherichia coli O157:H7 str. EC4115 6971837 YP_002273821.1 CDS ECH74115_5801 NC_011353.1 5433847 5434950 R hypothetical protein complement(5433847..5434950) Escherichia coli O157:H7 str. EC4115 6967343 YP_002273822.1 CDS ECH74115_5802 NC_011353.1 5434954 5435661 R hypothetical protein complement(5434954..5435661) Escherichia coli O157:H7 str. EC4115 6966861 YP_002273823.1 CDS ECH74115_5803 NC_011353.1 5435668 5437320 R hypothetical protein complement(5435668..5437320) Escherichia coli O157:H7 str. EC4115 6967837 YP_002273824.1 CDS ECH74115_5804 NC_011353.1 5437584 5437703 R identified by glimmer; hypothetical protein complement(5437584..5437703) Escherichia coli O157:H7 str. EC4115 6967224 YP_002273825.1 CDS ECH74115_5805 NC_011353.1 5437955 5440891 D identified by glimmer; hypothetical protein 5437955..5440891 Escherichia coli O157:H7 str. EC4115 6969043 YP_002273826.1 CDS ECH74115_5807 NC_011353.1 5440891 5447205 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369; DEAD/DEAH box helicase 5440891..5447205 Escherichia coli O157:H7 str. EC4115 6968318 YP_002273827.1 CDS ECH74115_5806 NC_011353.1 5447192 5447308 R identified by glimmer; hypothetical protein complement(5447192..5447308) Escherichia coli O157:H7 str. EC4115 6971808 YP_002273828.1 CDS ECH74115_5808 NC_011353.1 5447429 5450287 D identified by match to protein family HMM PF00176; match to protein family HMM PF00271; helicase family protein 5447429..5450287 Escherichia coli O157:H7 str. EC4115 6969836 YP_002273829.1 CDS ECH74115_5809 NC_011353.1 5450290 5455224 D identified by glimmer; hypothetical protein 5450290..5455224 Escherichia coli O157:H7 str. EC4115 6969870 YP_002273830.1 CDS ECH74115_5810 NC_011353.1 5455224 5461565 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369; DEAD/DEAH box helicase 5455224..5461565 Escherichia coli O157:H7 str. EC4115 6971382 YP_002273831.1 CDS ECH74115_5811 NC_011353.1 5461562 5463676 D identified by match to protein family HMM PF00580; ATP-dependent DNA helicase, UvrD/REP family 5461562..5463676 Escherichia coli O157:H7 str. EC4115 6970842 YP_002273832.1 CDS ECH74115_5813 NC_011353.1 5465170 5466150 R identified by match to protein family HMM PF03629; hypothetical protein complement(5465170..5466150) Escherichia coli O157:H7 str. EC4115 6966721 YP_002273833.1 CDS ECH74115_5814 NC_011353.1 5466215 5467321 R identified by match to protein family HMM PF01344; match to protein family HMM PF07646; match to protein family HMM TIGR03547; N-acetylneuraminic acid mutarotase complement(5466215..5467321) Escherichia coli O157:H7 str. EC4115 6968185 YP_002273834.1 CDS ECH74115_5815 NC_011353.1 5467341 5467889 R identified by match to protein family HMM PF06178; oligogalacturonate-specific porin protein complement(5467341..5467889) Escherichia coli O157:H7 str. EC4115 6968997 YP_002273835.1 CDS ECH74115_5816 NC_011353.1 5468295 5468423 D identified by glimmer; hypothetical protein 5468295..5468423 Escherichia coli O157:H7 str. EC4115 6969813 YP_002273836.1 CDS ECH74115_5817 NC_011353.1 5468722 5468859 R identified by glimmer; hypothetical protein complement(5468722..5468859) Escherichia coli O157:H7 str. EC4115 6970576 YP_002273837.1 CDS fimB NC_011353.1 5469513 5470115 D inversion of on/off regulator of fimA; tyrosine recombinase 5469513..5470115 Escherichia coli O157:H7 str. EC4115 6971994 YP_002273838.1 CDS fimE NC_011353.1 5470593 5471189 D inversion of on/off regulator of fimA; tyrosine recombinase 5470593..5471189 Escherichia coli O157:H7 str. EC4115 6971688 YP_002273839.1 CDS ECH74115_5820 NC_011353.1 5471654 5472202 D identified by match to protein family HMM PF00419; type-1 fimbrial protein-like protein 5471654..5472202 Escherichia coli O157:H7 str. EC4115 6969658 YP_002273840.1 CDS ECH74115_5821 NC_011353.1 5472309 5472806 D identified by match to protein family HMM PF00419; type-1 fimbrial protein-like protein 5472309..5472806 Escherichia coli O157:H7 str. EC4115 6966892 YP_002273841.1 CDS fimC NC_011353.1 5472843 5473568 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC 5472843..5473568 Escherichia coli O157:H7 str. EC4115 6967707 YP_002273842.1 CDS fimD1 NC_011353.1 5473635 5476271 D identified by match to protein family HMM PF00577; outer membrane usher protein fimD 5473635..5476271 Escherichia coli O157:H7 str. EC4115 6970739 YP_002273843.1 CDS fimF NC_011353.1 5476281 5476811 D identified by match to protein family HMM PF00419; fimbrial protein FimF 5476281..5476811 Escherichia coli O157:H7 str. EC4115 6968638 YP_002273844.1 CDS fimG NC_011353.1 5476824 5477327 D identified by match to protein family HMM PF00419; protein fimG 5476824..5477327 Escherichia coli O157:H7 str. EC4115 6971549 YP_002273845.1 CDS fimH NC_011353.1 5477347 5478249 D identified by match to protein family HMM PF00419; match to protein family HMM PF09160; protein FimH 5477347..5478249 Escherichia coli O157:H7 str. EC4115 6969617 YP_002273846.1 CDS gntP NC_011353.1 5478423 5479766 R identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; fructuronate transporter complement(5478423..5479766) Escherichia coli O157:H7 str. EC4115 6971027 YP_002273847.1 CDS uxuA NC_011353.1 5480106 5481290 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5480106..5481290 Escherichia coli O157:H7 str. EC4115 6971872 YP_002273848.1 CDS uxuB NC_011353.1 5481371 5482831 D identified by match to protein family HMM PF01232; match to protein family HMM PF08125; fructuronate reductase 5481371..5482831 Escherichia coli O157:H7 str. EC4115 6969809 YP_002273849.1 CDS ECH74115_5830 NC_011353.1 5483046 5483819 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5483046..5483819 Escherichia coli O157:H7 str. EC4115 6970609 YP_002273850.1 CDS ECH74115_5831 NC_011353.1 5483960 5484790 R hypothetical protein complement(5483960..5484790) Escherichia coli O157:H7 str. EC4115 6971368 YP_002273851.1 CDS ECH74115_5832 NC_011353.1 5485124 5485267 D identified by glimmer; hypothetical protein 5485124..5485267 Escherichia coli O157:H7 str. EC4115 6972198 YP_002273852.1 CDS ECH74115_5833 NC_011353.1 5485363 5485497 D identified by glimmer; hypothetical protein 5485363..5485497 Escherichia coli O157:H7 str. EC4115 6968635 YP_002273853.1 CDS iraD NC_011353.1 5485463 5485855 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5485463..5485855 Escherichia coli O157:H7 str. EC4115 6969090 YP_002273854.1 CDS iadA NC_011353.1 5486824 5487996 R identified by match to protein family HMM PF01979; match to protein family HMM TIGR01975; isoaspartyl dipeptidase complement(5486824..5487996) Escherichia coli O157:H7 str. EC4115 6967133 YP_002273855.1 CDS ECH74115_5837 NC_011353.1 5488009 5488470 R identified by match to protein family HMM PF07670; hypothetical protein complement(5488009..5488470) Escherichia coli O157:H7 str. EC4115 6971583 YP_002273856.1 CDS ECH74115_5838 NC_011353.1 5488467 5489150 R identified by match to protein family HMM PF07670; transporter complement(5488467..5489150) Escherichia coli O157:H7 str. EC4115 6969542 YP_002273857.1 CDS ECH74115_5839 NC_011353.1 5489180 5489371 D identified by glimmer; hypothetical protein 5489180..5489371 Escherichia coli O157:H7 str. EC4115 6971457 YP_002273858.1 CDS ECH74115_5844 NC_011353.1 5495559 5496737 R identified by match to protein family HMM PF06779; match to protein family HMM PF07690; major facilitator family transporter complement(5495559..5496737) Escherichia coli O157:H7 str. EC4115 6968143 YP_002273859.1 CDS ECH74115_5845 NC_011353.1 5496805 5497647 R identified by match to protein family HMM PF06977; SdiA-regulated protein complement(5496805..5497647) Escherichia coli O157:H7 str. EC4115 6967407 YP_002273860.1 CDS ECH74115_5846 NC_011353.1 5497913 5500096 R identified by glimmer; hypothetical protein complement(5497913..5500096) Escherichia coli O157:H7 str. EC4115 6966617 YP_002273861.1 CDS ECH74115_5847 NC_011353.1 5500408 5500674 R hypothetical protein complement(5500408..5500674) Escherichia coli O157:H7 str. EC4115 6971096 YP_002273862.1 CDS hgdC NC_011353.1 5500671 5501438 R identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; (R)-2-hydroxyglutaryl-CoA dehydratase activator complement(5500671..5501438) Escherichia coli O157:H7 str. EC4115 6971534 YP_002273863.1 CDS ECH74115_5849 NC_011353.1 5501448 5502599 R identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D complement(5501448..5502599) Escherichia coli O157:H7 str. EC4115 6969397 YP_002273864.1 CDS ECH74115_5850 NC_011353.1 5502715 5503986 R identified by match to protein family HMM PF04286; hypothetical protein complement(5502715..5503986) Escherichia coli O157:H7 str. EC4115 6969280 YP_002273865.1 CDS mdtM NC_011353.1 5504027 5505259 R identified by match to protein family HMM PF07690; multidrug resistance protein MdtM complement(5504027..5505259) Escherichia coli O157:H7 str. EC4115 6971352 YP_002273866.1 CDS ECH74115_5852 NC_011353.1 5505517 5505690 D identified by glimmer; hypothetical protein 5505517..5505690 Escherichia coli O157:H7 str. EC4115 6970526 YP_002273867.1 CDS ECH74115_5854 NC_011353.1 5506926 5508338 R identified by match to protein family HMM PF00155; match to protein family HMM PF00392; transcriptional regulator, GntR family/aminotransferase, classes I and II complement(5506926..5508338) Escherichia coli O157:H7 str. EC4115 6971890 YP_002273868.1 CDS ECH74115_5855 NC_011353.1 5508515 5508679 D identified by match to protein family HMM PF06568; hypothetical protein 5508515..5508679 Escherichia coli O157:H7 str. EC4115 6968774 YP_002273869.1 CDS ECH74115_5858 NC_011353.1 5510915 5511256 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(5510915..5511256) Escherichia coli O157:H7 str. EC4115 6968527 YP_002273870.1 CDS ECH74115_5859 NC_011353.1 5511477 5513231 R identified by match to protein family HMM PF01420; type I restriction-modification system subunit S complement(5511477..5513231) Escherichia coli O157:H7 str. EC4115 6967589 YP_002273871.1 CDS ECH74115_5860 NC_011353.1 5513231 5514712 R identified by match to protein family HMM PF01170; match to protein family HMM PF02384; type I restriction-modification system, M subunit complement(5513231..5514712) Escherichia coli O157:H7 str. EC4115 6967376 YP_002273872.1 CDS ECH74115_5861 NC_011353.1 5514767 5517199 R identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463; type III restriction enzyme domain-containing protein complement(5514767..5517199) Escherichia coli O157:H7 str. EC4115 6969406 YP_002273873.1 CDS ECH74115_5864 NC_011353.1 5519197 5520153 R identified by match to protein family HMM PF02492; match to protein family HMM PF07683; GTP-binding protein YjiA complement(5519197..5520153) Escherichia coli O157:H7 str. EC4115 6970238 YP_002273874.1 CDS ECH74115_5865 NC_011353.1 5520164 5520367 R identified by match to protein family HMM PF04328; hypothetical protein complement(5520164..5520367) Escherichia coli O157:H7 str. EC4115 6971041 YP_002273875.1 CDS ECH74115_5866 NC_011353.1 5520417 5522582 R identified by match to protein family HMM PF02554; carbon starvation family protein complement(5520417..5522582) Escherichia coli O157:H7 str. EC4115 6971842 YP_002273876.1 CDS ECH74115_5867 NC_011353.1 5522860 5523402 R hypothetical protein complement(5522860..5523402) Escherichia coli O157:H7 str. EC4115 6966969 YP_002273877.1 CDS tsr NC_011353.1 5523631 5525295 D identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein I 5523631..5525295 Escherichia coli O157:H7 str. EC4115 6966688 YP_002273878.1 CDS ECH74115_5869 NC_011353.1 5525344 5526705 R identified by match to protein family HMM PF07690; major facilitator family transporter complement(5525344..5526705) Escherichia coli O157:H7 str. EC4115 6967601 YP_002273879.1 CDS ECH74115_5870 NC_011353.1 5526920 5527834 R identified by match to protein family HMM PF07729; GntR family transcriptional regulator complement(5526920..5527834) Escherichia coli O157:H7 str. EC4115 6967042 YP_002273880.1 CDS ECH74115_5871 NC_011353.1 5527973 5528995 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 5527973..5528995 Escherichia coli O157:H7 str. EC4115 6969227 YP_002273881.1 CDS mdoB NC_011353.1 5529132 5531423 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(5529132..5531423) Escherichia coli O157:H7 str. EC4115 6968063 YP_002273882.1 CDS ECH74115_5873 NC_011353.1 5531677 5532174 R hypothetical protein complement(5531677..5532174) Escherichia coli O157:H7 str. EC4115 6969698 YP_002273883.1 CDS dnaC NC_011353.1 5532220 5532957 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(5532220..5532957) Escherichia coli O157:H7 str. EC4115 6968904 YP_002273884.1 CDS dnaT NC_011353.1 5532960 5533499 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(5532960..5533499) Escherichia coli O157:H7 str. EC4115 6970601 YP_002273885.1 CDS ECH74115_5876 NC_011353.1 5533606 5534079 R overlaps another CDS with the same product name; hypothetical protein complement(5533606..5534079) Escherichia coli O157:H7 str. EC4115 6969790 YP_002273886.1 CDS ECH74115_5877 NC_011353.1 5534070 5534894 R overlaps another CDS with the same product name; identified by match to protein family HMM PF06738; hypothetical protein complement(5534070..5534894) Escherichia coli O157:H7 str. EC4115 6966970 YP_002273887.1 CDS ECH74115_5878 NC_011353.1 5535461 5536186 D overlaps another CDS with the same product name; identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 5535461..5536186 Escherichia coli O157:H7 str. EC4115 6972229 YP_002273888.1 CDS ECH74115_5879 NC_011353.1 5536144 5536821 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5536144..5536821 Escherichia coli O157:H7 str. EC4115 6970831 YP_002273889.1 CDS fhuF NC_011353.1 5536859 5537647 R identified by match to protein family HMM PF06276; ferric hydroximate transport ferric iron reductase complement(5536859..5537647) Escherichia coli O157:H7 str. EC4115 6970376 YP_002273890.1 CDS ECH74115_5881 NC_011353.1 5537749 5538024 D identified by match to protein family HMM PF07256; hypothetical protein 5537749..5538024 Escherichia coli O157:H7 str. EC4115 6967913 YP_002273891.1 CDS rsmC NC_011353.1 5538339 5539370 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(5538339..5539370) Escherichia coli O157:H7 str. EC4115 6972339 YP_002273892.1 CDS holD NC_011353.1 5539473 5539886 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5539473..5539886 Escherichia coli O157:H7 str. EC4115 6969181 YP_002273893.1 CDS rimI NC_011353.1 5539855 5540301 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5539855..5540301 Escherichia coli O157:H7 str. EC4115 6968315 YP_002273894.1 CDS yjjG NC_011353.1 5540316 5540993 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5540316..5540993 Escherichia coli O157:H7 str. EC4115 6970398 YP_002273895.1 CDS prfC NC_011353.1 5541084 5542673 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5541084..5542673 Escherichia coli O157:H7 str. EC4115 6969765 YP_002273896.1 CDS osmY NC_011353.1 5543066 5543671 D identified by match to protein family HMM PF04972; hypothetical protein 5543066..5543671 Escherichia coli O157:H7 str. EC4115 6970163 YP_002273897.1 CDS ECH74115_5889 NC_011353.1 5543798 5543959 D identified by glimmer; hypothetical protein 5543798..5543959 Escherichia coli O157:H7 str. EC4115 6969521 YP_002273898.1 CDS ECH74115_5890 NC_011353.1 5544081 5545154 D identified by match to protein family HMM PF01734; phospholipase, patatin family 5544081..5545154 Escherichia coli O157:H7 str. EC4115 6972051 YP_002273899.1 CDS ECH74115_5891 NC_011353.1 5545151 5545933 D identified by match to protein family HMM PF01026; deoxyribonuclease YjjV 5545151..5545933 Escherichia coli O157:H7 str. EC4115 6969804 YP_002273900.1 CDS ECH74115_5892 NC_011353.1 5546147 5547010 R identified by match to protein family HMM PF04055; radical SAM domain-containing protein complement(5546147..5547010) Escherichia coli O157:H7 str. EC4115 6968231 YP_002273901.1 CDS ECH74115_5895 NC_011353.1 5548507 5548632 D hypothetical protein 5548507..5548632 Escherichia coli O157:H7 str. EC4115 6966671 YP_002273902.1 CDS deoC NC_011353.1 5548789 5549568 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5548789..5549568 Escherichia coli O157:H7 str. EC4115 6967866 YP_002273903.1 CDS deoA NC_011353.1 5549695 5551017 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5549695..5551017 Escherichia coli O157:H7 str. EC4115 6971427 YP_002273904.1 CDS deoB NC_011353.1 5551069 5552292 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5551069..5552292 Escherichia coli O157:H7 str. EC4115 6969774 YP_002273905.1 CDS deoD NC_011353.1 5552349 5553068 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5552349..5553068 Escherichia coli O157:H7 str. EC4115 6970592 YP_002273906.1 CDS ECH74115_5900 NC_011353.1 5553229 5553492 R identified by match to protein family HMM PF01381; hypothetical protein complement(5553229..5553492) Escherichia coli O157:H7 str. EC4115 6971702 YP_002273907.1 CDS ECH74115_5901 NC_011353.1 5553524 5555212 R in E. coli the lipoate ligase A catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes; creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; hypothetical protein/lipoate-protein ligase A fusion protein complement(5553524..5555212) Escherichia coli O157:H7 str. EC4115 6970887 YP_002273908.1 CDS serB NC_011353.1 5555318 5556286 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5555318..5556286 Escherichia coli O157:H7 str. EC4115 6970436 YP_002273909.1 CDS radA NC_011353.1 5556335 5557717 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5556335..5557717 Escherichia coli O157:H7 str. EC4115 6969581 YP_002273910.1 CDS nadR NC_011353.1 5557738 5558970 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5557738..5558970 Escherichia coli O157:H7 str. EC4115 6968279 YP_002273911.1 CDS ECH74115_5905 NC_011353.1 5559004 5559171 D hypothetical protein 5559004..5559171 Escherichia coli O157:H7 str. EC4115 6968885 YP_002273912.1 CDS ECH74115_5906 NC_011353.1 5559278 5560945 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(5559278..5560945) Escherichia coli O157:H7 str. EC4115 6966645 YP_002273913.1 CDS slt NC_011353.1 5561156 5563093 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5561156..5563093 Escherichia coli O157:H7 str. EC4115 6971510 YP_002273914.1 CDS trpR NC_011353.1 5563183 5563509 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5563183..5563509 Escherichia coli O157:H7 str. EC4115 6971492 YP_002273915.1 CDS ECH74115_5909 NC_011353.1 5563656 5564177 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(5563656..5564177) Escherichia coli O157:H7 str. EC4115 6972146 YP_002273916.1 CDS ECH74115_5911 NC_011353.1 5564220 5564867 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5564220..5564867 Escherichia coli O157:H7 str. EC4115 6969170 YP_002273917.1 CDS rob NC_011353.1 5564864 5565733 R identified by match to protein family HMM PF00165; match to protein family HMM PF06445; right origin-binding protein complement(5564864..5565733) Escherichia coli O157:H7 str. EC4115 6967969 YP_002273918.1 CDS ECH74115_5912 NC_011353.1 5565944 5566417 D identified by match to protein family HMM PF05981; hypothetical protein 5565944..5566417 Escherichia coli O157:H7 str. EC4115 6968360 YP_002273919.1 CDS creB NC_011353.1 5566430 5567119 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5566430..5567119 Escherichia coli O157:H7 str. EC4115 6970384 YP_002273920.1 CDS creC NC_011353.1 5567119 5568543 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5567119..5568543 Escherichia coli O157:H7 str. EC4115 6971167 YP_002273921.1 CDS ECH74115_5915 NC_011353.1 5568601 5569953 D identified by match to protein family HMM PF06123; hypothetical protein 5568601..5569953 Escherichia coli O157:H7 str. EC4115 6967322 YP_002273922.1 CDS arcA NC_011353.1 5570013 5570729 R identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two-component response regulator complement(5570013..5570729) Escherichia coli O157:H7 str. EC4115 6967034 YP_002273923.1 CDS ECH74115_5917 NC_011353.1 5571365 5572051 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5571365..5572051 Escherichia coli O157:H7 str. EC4115 6969087 ECH74115_0213 tRNA ECH74115_0213 NC_011353.1 228693 228769 D tRNA-Ile 228693..228769 Escherichia coli O157:H7 str. EC4115 6972272 ECH74115_0214 tRNA ECH74115_0214 NC_011353.1 228811 228888 D tRNA-Ala 228811..228888 Escherichia coli O157:H7 str. EC4115 6972407 ECH74115_0218 tRNA ECH74115_0218 NC_011353.1 232239 232317 D tRNA-Asp 232239..232317 Escherichia coli O157:H7 str. EC4115 6972273 ECH74115_0228 tRNA ECH74115_0228 NC_011353.1 240463 240541 D tRNA-Asp 240463..240541 Escherichia coli O157:H7 str. EC4115 6972128 ECH74115_0289 tRNA ECH74115_0289 NC_011353.1 302543 302618 D tRNA-Thr 302543..302618 Escherichia coli O157:H7 str. EC4115 6968809 ECH74115_0398 tRNA ECH74115_0398 NC_011353.1 405913 405993 D tRNA-OTHER 405913..405993 Escherichia coli O157:H7 str. EC4115 6968968 ECH74115_0638 tRNA ECH74115_0638 NC_011353.1 660457 660535 D tRNA-Arg 660457..660535 Escherichia coli O157:H7 str. EC4115 6969778 ECH74115_0757 tRNA ECH74115_0757 NC_011353.1 779865 779941 R tRNA-Gln complement(779865..779941) Escherichia coli O157:H7 str. EC4115 6971812 ECH74115_0758 tRNA ECH74115_0758 NC_011353.1 779977 780053 R tRNA-Gln complement(779977..780053) Escherichia coli O157:H7 str. EC4115 6972387 ECH74115_0759 tRNA ECH74115_0759 NC_011353.1 780100 780178 R tRNA-Met complement(780100..780178) Escherichia coli O157:H7 str. EC4115 6972355 ECH74115_0760 tRNA ECH74115_0760 NC_011353.1 780192 780268 R tRNA-Gln complement(780192..780268) Escherichia coli O157:H7 str. EC4115 6972351 ECH74115_0761 tRNA ECH74115_0761 NC_011353.1 780302 780376 R tRNA-Gln complement(780302..780376) Escherichia coli O157:H7 str. EC4115 6972401 ECH74115_0762 tRNA ECH74115_0762 NC_011353.1 780399 780485 R tRNA-Leu complement(780399..780485) Escherichia coli O157:H7 str. EC4115 6972421 ECH74115_0763 tRNA ECH74115_0763 NC_011353.1 780494 780572 R tRNA-Met complement(780494..780572) Escherichia coli O157:H7 str. EC4115 6972363 ECH74115_0846 tRNA ECH74115_0846 NC_011353.1 868339 868416 D tRNA-Lys 868339..868416 Escherichia coli O157:H7 str. EC4115 6966566 ECH74115_0847 tRNA ECH74115_0847 NC_011353.1 868451 868526 D tRNA-Val 868451..868526 Escherichia coli O157:H7 str. EC4115 6972397 ECH74115_0848 tRNA ECH74115_0848 NC_011353.1 868529 868604 D tRNA-Lys 868529..868604 Escherichia coli O157:H7 str. EC4115 6972361 ECH74115_0849 tRNA ECH74115_0849 NC_011353.1 868656 868731 D tRNA-Val 868656..868731 Escherichia coli O157:H7 str. EC4115 6972333 ECH74115_0850 tRNA ECH74115_0850 NC_011353.1 868735 868810 D tRNA-Lys 868735..868810 Escherichia coli O157:H7 str. EC4115 6972408 ECH74115_0851 tRNA ECH74115_0851 NC_011353.1 868956 869033 D tRNA-Lys 868956..869033 Escherichia coli O157:H7 str. EC4115 6972419 ECH74115_1045 tRNA ECH74115_1045 NC_011353.1 1060316 1060405 R tRNA-Ser complement(1060316..1060405) Escherichia coli O157:H7 str. EC4115 6968877 ECH74115_1165 tRNA ECH74115_1165 NC_011353.1 1182760 1182835 D tRNA-Met 1182760..1182835 Escherichia coli O157:H7 str. EC4115 6970120 ECH74115_1166 tRNA ECH74115_1166 NC_011353.1 1182842 1182920 D tRNA-Arg 1182842..1182920 Escherichia coli O157:H7 str. EC4115 6972331 ECH74115_1167 tRNA ECH74115_1167 NC_011353.1 1182932 1183010 D tRNA-Arg 1182932..1183010 Escherichia coli O157:H7 str. EC4115 6972332 ECH74115_1206 tRNA ECH74115_1206 NC_011353.1 1215778 1215867 R tRNA-Ser complement(1215778..1215867) Escherichia coli O157:H7 str. EC4115 6970724 ECH74115_1410 tRNA ECH74115_1410 NC_011353.1 1400290 1400379 R tRNA-Ser complement(1400290..1400379) Escherichia coli O157:H7 str. EC4115 6971618 ECH74115_1714 tRNA ECH74115_1714 NC_011353.1 1653784 1653870 R tRNA-Tyr complement(1653784..1653870) Escherichia coli O157:H7 str. EC4115 6972255 ECH74115_1716 tRNA ECH74115_1716 NC_011353.1 1654078 1654164 R tRNA-Tyr complement(1654078..1654164) Escherichia coli O157:H7 str. EC4115 6972257 ECH74115_1768 tRNA ECH74115_1768 NC_011353.1 1695522 1695597 D tRNA-Met 1695522..1695597 Escherichia coli O157:H7 str. EC4115 6971010 ECH74115_1769 tRNA ECH74115_1769 NC_011353.1 1695677 1695755 D tRNA-Arg 1695677..1695755 Escherichia coli O157:H7 str. EC4115 6972329 ECH74115_1850 tRNA ECH74115_1850 NC_011353.1 1753682 1753756 D tRNA-Met 1753682..1753756 Escherichia coli O157:H7 str. EC4115 6968263 ECH74115_2192 tRNA ECH74115_2192 NC_011353.1 2097556 2097634 R tRNA-Arg complement(2097556..2097634) Escherichia coli O157:H7 str. EC4115 6967963 ECH74115_2193 tRNA ECH74115_2193 NC_011353.1 2097734 2097809 R tRNA-Met complement(2097734..2097809) Escherichia coli O157:H7 str. EC4115 6972365 ECH74115_2262 tRNA ECH74115_2262 NC_011353.1 2145466 2145544 R tRNA-Arg complement(2145466..2145544) Escherichia coli O157:H7 str. EC4115 6969486 ECH74115_2263 tRNA ECH74115_2263 NC_011353.1 2145556 2145634 R tRNA-Arg complement(2145556..2145634) Escherichia coli O157:H7 str. EC4115 6972380 ECH74115_2264 tRNA ECH74115_2264 NC_011353.1 2145641 2145716 R tRNA-Met complement(2145641..2145716) Escherichia coli O157:H7 str. EC4115 6972420 ECH74115_2378 tRNA ECH74115_2378 NC_011353.1 2252440 2252518 D tRNA-Val 2252440..2252518 Escherichia coli O157:H7 str. EC4115 6969995 ECH74115_2379 tRNA ECH74115_2379 NC_011353.1 2252521 2252599 D tRNA-Val 2252521..2252599 Escherichia coli O157:H7 str. EC4115 6972405 ECH74115_2681 tRNA ECH74115_2681 NC_011353.1 2521697 2521783 R tRNA-Leu complement(2521697..2521783) Escherichia coli O157:H7 str. EC4115 6970632 ECH74115_2682 tRNA ECH74115_2682 NC_011353.1 2521796 2521869 R tRNA-Cys complement(2521796..2521869) Escherichia coli O157:H7 str. EC4115 6972403 ECH74115_2683 tRNA ECH74115_2683 NC_011353.1 2521923 2521998 R tRNA-Gly complement(2521923..2521998) Escherichia coli O157:H7 str. EC4115 6972431 ECH74115_2794 tRNA ECH74115_2794 NC_011353.1 2605369 2605447 R tRNA-Arg complement(2605369..2605447) Escherichia coli O157:H7 str. EC4115 6967292 ECH74115_2795 tRNA ECH74115_2795 NC_011353.1 2605459 2605537 R tRNA-Arg complement(2605459..2605537) Escherichia coli O157:H7 str. EC4115 6972362 ECH74115_2796 tRNA ECH74115_2796 NC_011353.1 2605544 2605619 R tRNA-Met complement(2605544..2605619) Escherichia coli O157:H7 str. EC4115 6972347 ECH74115_2818 tRNA ECH74115_2818 NC_011353.1 2619661 2619752 R tRNA-Ser complement(2619661..2619752) Escherichia coli O157:H7 str. EC4115 6971160 ECH74115_2820 tRNA ECH74115_2820 NC_011353.1 2620742 2620819 D tRNA-Asn 2620742..2620819 Escherichia coli O157:H7 str. EC4115 6969286 ECH74115_2828 tRNA ECH74115_2828 NC_011353.1 2635122 2635199 R tRNA-Asn complement(2635122..2635199) Escherichia coli O157:H7 str. EC4115 6966663 ECH74115_2830 tRNA ECH74115_2830 NC_011353.1 2636946 2637023 D tRNA-Asn 2636946..2637023 Escherichia coli O157:H7 str. EC4115 6970916 ECH74115_2834 tRNA ECH74115_2834 NC_011353.1 2639354 2639431 D tRNA-Asn 2639354..2639431 Escherichia coli O157:H7 str. EC4115 6971695 ECH74115_2907 tRNA ECH74115_2907 NC_011353.1 2697534 2697612 R tRNA-Arg complement(2697534..2697612) Escherichia coli O157:H7 str. EC4115 6968648 ECH74115_2908 tRNA ECH74115_2908 NC_011353.1 2697624 2697702 R tRNA-Arg complement(2697624..2697702) Escherichia coli O157:H7 str. EC4115 6972336 ECH74115_2909 tRNA ECH74115_2909 NC_011353.1 2697703 2697778 R tRNA-Met complement(2697703..2697778) Escherichia coli O157:H7 str. EC4115 6972433 ECH74115_3149 tRNA ECH74115_3149 NC_011353.1 2918643 2918717 R tRNA-Met complement(2918643..2918717) Escherichia coli O157:H7 str. EC4115 6967664 ECH74115_3216 tRNA ECH74115_3216 NC_011353.1 2964099 2964175 R tRNA-Arg complement(2964099..2964175) Escherichia coli O157:H7 str. EC4115 6970442 ECH74115_3217 tRNA ECH74115_3217 NC_011353.1 2964188 2964266 R tRNA-Arg complement(2964188..2964266) Escherichia coli O157:H7 str. EC4115 6972328 ECH74115_3218 tRNA ECH74115_3218 NC_011353.1 2964275 2964350 R tRNA-Met complement(2964275..2964350) Escherichia coli O157:H7 str. EC4115 6972409 ECH74115_3328 tRNA ECH74115_3328 NC_011353.1 3062502 3062580 D tRNA-Pro 3062502..3062580 Escherichia coli O157:H7 str. EC4115 6966583 ECH74115_3534 tRNA ECH74115_3534 NC_011353.1 3272337 3272415 R tRNA-Arg complement(3272337..3272415) Escherichia coli O157:H7 str. EC4115 6967024 ECH74115_3535 tRNA ECH74115_3535 NC_011353.1 3272427 3272505 R tRNA-Arg complement(3272427..3272505) Escherichia coli O157:H7 str. EC4115 6972394 ECH74115_3536 tRNA ECH74115_3536 NC_011353.1 3272512 3272587 R tRNA-Met complement(3272512..3272587) Escherichia coli O157:H7 str. EC4115 6972393 ECH74115_3581 tRNA ECH74115_3581 NC_011353.1 3297023 3297099 D tRNA-Arg 3297023..3297099 Escherichia coli O157:H7 str. EC4115 6971789 ECH74115_3626 tRNA ECH74115_3626 NC_011353.1 3348939 3349016 R tRNA-Ala complement(3348939..3349016) Escherichia coli O157:H7 str. EC4115 6971289 ECH74115_3627 tRNA ECH74115_3627 NC_011353.1 3349055 3349130 R tRNA-Ala complement(3349055..3349130) Escherichia coli O157:H7 str. EC4115 6972344 ECH74115_3634 tRNA ECH74115_3634 NC_011353.1 3353577 3353652 D tRNA-Val 3353577..3353652 Escherichia coli O157:H7 str. EC4115 6971936 ECH74115_3635 tRNA ECH74115_3635 NC_011353.1 3353696 3353773 D tRNA-Val 3353696..3353773 Escherichia coli O157:H7 str. EC4115 6972342 ECH74115_3636 tRNA ECH74115_3636 NC_011353.1 3353818 3353895 D tRNA-Val 3353818..3353895 Escherichia coli O157:H7 str. EC4115 6972327 ECH74115_3637 tRNA ECH74115_3637 NC_011353.1 3353899 3353974 D tRNA-Lys 3353899..3353974 Escherichia coli O157:H7 str. EC4115 6972348 ECH74115_3830 tRNA ECH74115_3830 NC_011353.1 3553682 3553759 R tRNA-Glu complement(3553682..3553759) Escherichia coli O157:H7 str. EC4115 6972283 ECH74115_3898 tRNA ECH74115_3898 NC_011353.1 3612183 3612258 R tRNA-Met complement(3612183..3612258) Escherichia coli O157:H7 str. EC4115 6969760 ECH74115_3937 tRNA ECH74115_3937 NC_011353.1 3646177 3646255 R tRNA-Arg complement(3646177..3646255) Escherichia coli O157:H7 str. EC4115 6967197 ECH74115_3938 tRNA ECH74115_3938 NC_011353.1 3646356 3646434 R tRNA-Arg complement(3646356..3646434) Escherichia coli O157:H7 str. EC4115 6972426 ECH74115_3939 tRNA ECH74115_3939 NC_011353.1 3646495 3646573 R tRNA-Arg complement(3646495..3646573) Escherichia coli O157:H7 str. EC4115 6972418 ECH74115_3940 tRNA ECH74115_3940 NC_011353.1 3646636 3646714 R tRNA-Arg complement(3646636..3646714) Escherichia coli O157:H7 str. EC4115 6972389 ECH74115_3941 tRNA ECH74115_3941 NC_011353.1 3646716 3646810 R tRNA-Ser complement(3646716..3646810) Escherichia coli O157:H7 str. EC4115 6972370 ECH74115_4079 tRNA ECH74115_4079 NC_011353.1 3774184 3774260 D tRNA-Met 3774184..3774260 Escherichia coli O157:H7 str. EC4115 6968683 ECH74115_4080 tRNA ECH74115_4080 NC_011353.1 3774294 3774370 D tRNA-Met 3774294..3774370 Escherichia coli O157:H7 str. EC4115 6972384 ECH74115_4081 tRNA ECH74115_4081 NC_011353.1 3774404 3774480 D tRNA-Met 3774404..3774480 Escherichia coli O157:H7 str. EC4115 6972366 ECH74115_4154 tRNA ECH74115_4154 NC_011353.1 3841710 3841785 R tRNA-Gly complement(3841710..3841785) Escherichia coli O157:H7 str. EC4115 6969189 ECH74115_4271 tRNA ECH74115_4271 NC_011353.1 3956356 3956433 D tRNA-Phe 3956356..3956433 Escherichia coli O157:H7 str. EC4115 6970080 ECH74115_4382 tRNA ECH74115_4382 NC_011353.1 4058211 4058288 D tRNA-Met 4058211..4058288 Escherichia coli O157:H7 str. EC4115 6971401 ECH74115_4492 tRNA ECH74115_4492 NC_011353.1 4162478 4162554 R tRNA-Met complement(4162478..4162554) Escherichia coli O157:H7 str. EC4115 6971941 ECH74115_4496 tRNA ECH74115_4496 NC_011353.1 4166336 4166424 R tRNA-Leu complement(4166336..4166424) Escherichia coli O157:H7 str. EC4115 6966790 ECH74115_4594 tRNA ECH74115_4594 NC_011353.1 4261664 4261741 R tRNA-Thr complement(4261664..4261741) Escherichia coli O157:H7 str. EC4115 6972280 ECH74115_4599 tRNA ECH74115_4599 NC_011353.1 4265050 4265127 R tRNA-Ala complement(4265050..4265127) Escherichia coli O157:H7 str. EC4115 6972275 ECH74115_4600 tRNA ECH74115_4600 NC_011353.1 4265169 4265245 R tRNA-Ile complement(4265169..4265245) Escherichia coli O157:H7 str. EC4115 6972364 ECH74115_4915 tRNA ECH74115_4915 NC_011353.1 4553543 4553621 R tRNA-Pro complement(4553543..4553621) Escherichia coli O157:H7 str. EC4115 6968421 ECH74115_5031 tRNA ECH74115_5031 NC_011353.1 4683873 4683967 D tRNA-Sec 4683873..4683967 Escherichia coli O157:H7 str. EC4115 6971189 ECH74115_5193 tRNA ECH74115_5193 NC_011353.1 4839973 4840050 D tRNA-Glu 4839973..4840050 Escherichia coli O157:H7 str. EC4115 6972266 ECH74115_5197 tRNA ECH74115_5197 NC_011353.1 4843412 4843490 D tRNA-Asp 4843412..4843490 Escherichia coli O157:H7 str. EC4115 6972268 ECH74115_5198 tRNA ECH74115_5198 NC_011353.1 4843497 4843574 D tRNA-Trp 4843497..4843574 Escherichia coli O157:H7 str. EC4115 6972353 ECH74115_5230 tRNA ECH74115_5230 NC_011353.1 4878877 4878953 D tRNA-Arg 4878877..4878953 Escherichia coli O157:H7 str. EC4115 6970039 ECH74115_5231 tRNA ECH74115_5231 NC_011353.1 4879011 4879088 D tRNA-His 4879011..4879088 Escherichia coli O157:H7 str. EC4115 6972406 ECH74115_5232 tRNA ECH74115_5232 NC_011353.1 4879107 4879195 D tRNA-Leu 4879107..4879195 Escherichia coli O157:H7 str. EC4115 6972381 ECH74115_5233 tRNA ECH74115_5233 NC_011353.1 4879237 4879312 D tRNA-Pro 4879237..4879312 Escherichia coli O157:H7 str. EC4115 6972410 ECH74115_5234 tRNA ECH74115_5234 NC_011353.1 4879333 4879421 D tRNA-Leu 4879333..4879421 Escherichia coli O157:H7 str. EC4115 6972385 ECH74115_5235 tRNA ECH74115_5235 NC_011353.1 4879462 4879540 D tRNA-Pro 4879462..4879540 Escherichia coli O157:H7 str. EC4115 6972436 ECH74115_5291 tRNA ECH74115_5291 NC_011353.1 4936379 4936455 D tRNA-Ile 4936379..4936455 Escherichia coli O157:H7 str. EC4115 6972267 ECH74115_5292 tRNA ECH74115_5292 NC_011353.1 4936497 4936574 D tRNA-Ala 4936497..4936574 Escherichia coli O157:H7 str. EC4115 6972373 ECH74115_5433 tRNA ECH74115_5433 NC_011353.1 5080666 5080743 D tRNA-Glu 5080666..5080743 Escherichia coli O157:H7 str. EC4115 6972271 ECH74115_5441 tRNA ECH74115_5441 NC_011353.1 5087517 5087594 D tRNA-Thr 5087517..5087594 Escherichia coli O157:H7 str. EC4115 6968787 ECH74115_5442 tRNA ECH74115_5442 NC_011353.1 5087602 5087686 D tRNA-Tyr 5087602..5087686 Escherichia coli O157:H7 str. EC4115 6972379 ECH74115_5443 tRNA ECH74115_5443 NC_011353.1 5087803 5087877 D tRNA-Gly 5087803..5087877 Escherichia coli O157:H7 str. EC4115 6972343 ECH74115_5444 tRNA ECH74115_5444 NC_011353.1 5087883 5087960 D tRNA-Thr 5087883..5087960 Escherichia coli O157:H7 str. EC4115 6972372 ECH74115_5478 tRNA ECH74115_5478 NC_011353.1 5121692 5121769 D tRNA-Glu 5121692..5121769 Escherichia coli O157:H7 str. EC4115 6972269 ECH74115_5650 tRNA ECH74115_5650 NC_011353.1 5292201 5292278 R tRNA-Phe complement(5292201..5292278) Escherichia coli O157:H7 str. EC4115 6969461 ECH74115_5679 tRNA ECH74115_5679 NC_011353.1 5321285 5321360 D tRNA-Gly 5321285..5321360 Escherichia coli O157:H7 str. EC4115 6969683 ECH74115_5680 tRNA ECH74115_5680 NC_011353.1 5321396 5321473 D tRNA-Gly 5321396..5321473 Escherichia coli O157:H7 str. EC4115 6972358 ECH74115_5681 tRNA ECH74115_5681 NC_011353.1 5321507 5321584 D tRNA-Gly 5321507..5321584 Escherichia coli O157:H7 str. EC4115 6972376 ECH74115_5788 tRNA ECH74115_5788 NC_011353.1 5422145 5422231 D tRNA-Leu 5422145..5422231 Escherichia coli O157:H7 str. EC4115 6967644 ECH74115_5882 tRNA ECH74115_5882 NC_011353.1 5538062 5538150 R tRNA-Leu complement(5538062..5538150) Escherichia coli O157:H7 str. EC4115 6967110 ECH74115_0212 rRNA rrs NC_011353.1 227083 228624 D 16S ribosomal RNA 227083..228624 Escherichia coli O157:H7 str. EC4115 6969709 ECH74115_0216 rRNA rrl NC_011353.1 229071 231975 D 23S ribosomal RNA 229071..231975 Escherichia coli O157:H7 str. EC4115 6972354 ECH74115_0217 rRNA rrf NC_011353.1 232070 232185 D 5S ribosomal RNA 232070..232185 Escherichia coli O157:H7 str. EC4115 6972263 ECH74115_3826 rRNA rrf NC_011353.1 3550383 3550498 R 5S ribosomal RNA complement(3550383..3550498) Escherichia coli O157:H7 str. EC4115 6968045 ECH74115_3827 rRNA rrl NC_011353.1 3550593 3553489 R 23S ribosomal RNA complement(3550593..3553489) Escherichia coli O157:H7 str. EC4115 6972276 ECH74115_3831 rRNA rrs NC_011353.1 3553844 3555385 R 16S ribosomal RNA complement(3553844..3555385) Escherichia coli O157:H7 str. EC4115 6972330 ECH74115_4593 rRNA rrf NC_011353.1 4261510 4261625 R 5S ribosomal RNA complement(4261510..4261625) Escherichia coli O157:H7 str. EC4115 6971758 ECH74115_4595 rRNA rrf NC_011353.1 4261755 4261870 R 5S ribosomal RNA complement(4261755..4261870) Escherichia coli O157:H7 str. EC4115 6972375 ECH74115_4596 rRNA rrl NC_011353.1 4261965 4264867 R 23S ribosomal RNA complement(4261965..4264867) Escherichia coli O157:H7 str. EC4115 6972274 ECH74115_4601 rRNA rrs NC_011353.1 4265314 4266855 R 16S ribosomal RNA complement(4265314..4266855) Escherichia coli O157:H7 str. EC4115 6972377 ECH74115_5192 rRNA rrs NC_011353.1 4838347 4839888 D 16S ribosomal RNA 4838347..4839888 Escherichia coli O157:H7 str. EC4115 6969317 ECH74115_5195 rRNA rrl NC_011353.1 4840243 4843148 D 23S ribosomal RNA 4840243..4843148 Escherichia coli O157:H7 str. EC4115 6972335 ECH74115_5196 rRNA rrf NC_011353.1 4843243 4843358 D 5S ribosomal RNA 4843243..4843358 Escherichia coli O157:H7 str. EC4115 6972264 ECH74115_5290 rRNA rrs NC_011353.1 4934769 4936310 D 16S ribosomal RNA 4934769..4936310 Escherichia coli O157:H7 str. EC4115 6968146 ECH74115_5294 rRNA rrl NC_011353.1 4936757 4939661 D 23S ribosomal RNA 4936757..4939661 Escherichia coli O157:H7 str. EC4115 6972400 ECH74115_5295 rRNA rrf NC_011353.1 4939756 4939871 D 5S ribosomal RNA 4939756..4939871 Escherichia coli O157:H7 str. EC4115 6972279 ECH74115_5432 rRNA rrs NC_011353.1 5079040 5080581 D 16S ribosomal RNA 5079040..5080581 Escherichia coli O157:H7 str. EC4115 6971976 ECH74115_5435 rRNA rrl NC_011353.1 5080936 5083840 D 23S ribosomal RNA 5080936..5083840 Escherichia coli O157:H7 str. EC4115 6972416 ECH74115_5436 rRNA rrf NC_011353.1 5083935 5084050 D 5S ribosomal RNA 5083935..5084050 Escherichia coli O157:H7 str. EC4115 6972278 ECH74115_5477 rRNA rrs NC_011353.1 5120066 5121607 D 16S ribosomal RNA 5120066..5121607 Escherichia coli O157:H7 str. EC4115 6970023 ECH74115_5480 rRNA rrl NC_011353.1 5121962 5124866 D 23S ribosomal RNA 5121962..5124866 Escherichia coli O157:H7 str. EC4115 6972399 ECH74115_5481 rRNA rrf NC_011353.1 5124961 5125076 D 5S ribosomal RNA 5124961..5125076 Escherichia coli O157:H7 str. EC4115 6972262