-- dump date 20140619_085720 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002268403.1 209395592 6966490 196..711 1 NC_011350.1 identified by match to protein family HMM PF02794; hemolysin-activating lysine-acyltransferase HlyC 711 6966490 ECH74115_B0017 Escherichia coli O157:H7 str. EC4115 hemolysin-activating lysine-acyltransferase HlyC YP_002268403.1 196 D 444450 CDS YP_002268404.1 209395598 6966441 713..3709 1 NC_011350.1 identified by match to protein family HMM PF00353; match to protein family HMM PF02382; match to protein family HMM PF08339; RTX C- domain protein 3709 6966441 ECH74115_B0018 Escherichia coli O157:H7 str. EC4115 RTX C- domain protein YP_002268404.1 713 D 444450 CDS YP_002268405.1 209395565 6966448 3759..5879 1 NC_011350.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846; type I secretion system ATPase family protein 5879 6966448 ECH74115_B0019 Escherichia coli O157:H7 str. EC4115 type I secretion system ATPase family protein YP_002268405.1 3759 D 444450 CDS YP_002268406.1 209395593 6966412 5883..7322 1 NC_011350.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843; leukotoxin secretion protein D 7322 6966412 ECH74115_B0020 Escherichia coli O157:H7 str. EC4115 leukotoxin secretion protein D YP_002268406.1 5883 D 444450 CDS YP_002268407.1 209395570 6966385 complement(7898..8095) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 8095 6966385 ECH74115_B0023 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268407.1 7898 R 444450 CDS YP_002268408.1 209395547 6966417 8417..9157 1 NC_011350.1 identified by match to protein family HMM PF00589; site-specific recombinase 9157 6966417 ECH74115_B0024 Escherichia coli O157:H7 str. EC4115 site-specific recombinase YP_002268408.1 8417 D 444450 CDS YP_002268409.1 209395567 6966393 9247..9366 1 NC_011350.1 hypothetical protein 9366 6966393 ECH74115_B0025 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268409.1 9247 D 444450 CDS YP_002268410.1 209395582 6966414 complement(9442..10419) 1 NC_011350.1 identified by match to protein family HMM PF01051; initiator RepB protein 10419 6966414 ECH74115_B0026 Escherichia coli O157:H7 str. EC4115 initiator RepB protein YP_002268410.1 9442 R 444450 CDS YP_002268411.1 209395555 6966430 complement(10412..10582) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 10582 6966430 ECH74115_B0027 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268411.1 10412 R 444450 CDS YP_002268412.1 209395557 6966401 10719..10832 1 NC_011350.1 hypothetical protein 10832 6966401 ECH74115_B0029 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268412.1 10719 D 444450 CDS YP_002268413.1 209395614 6966403 complement(10827..11027) 1 NC_011350.1 w0044 11027 6966403 ECH74115_B0028 Escherichia coli O157:H7 str. EC4115 w0044 YP_002268413.1 10827 R 444450 CDS YP_002268414.1 209395541 6966464 complement(11024..11644) 1 NC_011350.1 hypothetical protein 11644 6966464 ECH74115_B0030 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268414.1 11024 R 444450 CDS YP_002268415.1 209395535 6966384 complement(11641..12099) 1 NC_011350.1 hypothetical protein 12099 6966384 ECH74115_B0031 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268415.1 11641 R 444450 CDS YP_002268416.1 209395568 6966377 12112..12606 1 NC_011350.1 w0046 12606 6966377 ECH74115_B0032 Escherichia coli O157:H7 str. EC4115 w0046 YP_002268416.1 12112 D 444450 CDS YP_002268417.1 209395634 6966415 12783..13001 1 NC_011350.1 identified by match to protein family HMM PF07362; plasmid maintenance protein CcdA 13001 ccdA2 6966415 ccdA2 Escherichia coli O157:H7 str. EC4115 plasmid maintenance protein CcdA YP_002268417.1 12783 D 444450 CDS YP_002268418.1 209395601 6966440 complement(13055..13942) 1 NC_011350.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 13942 6966440 ECH74115_B0035 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002268418.1 13055 R 444450 CDS YP_002268419.1 209395583 6966451 complement(13942..14268) 1 NC_011350.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 14268 6966451 ECH74115_B0036 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002268419.1 13942 R 444450 CDS YP_002268420.1 209395551 6966431 14367..14621 1 NC_011350.1 controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 14621 6966431 ECH74115_B0037 Escherichia coli O157:H7 str. EC4115 plasmid maintenance protein CcdB YP_002268420.1 14367 D 444450 CDS YP_002268421.1 209395611 6966397 14622..15428 1 NC_011350.1 identified by match to protein family HMM PF00589; resolvase 15428 6966397 ECH74115_B0038 Escherichia coli O157:H7 str. EC4115 resolvase YP_002268421.1 14622 D 444450 CDS YP_002268422.1 209395589 6966461 15440..15562 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 15562 6966461 ECH74115_B0039 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268422.1 15440 D 444450 CDS YP_002268423.1 209395600 6966437 15622..15741 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 15741 6966437 ECH74115_B0040 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268423.1 15622 D 444450 CDS YP_002268424.1 209395591 6966450 complement(16151..17038) 1 NC_011350.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 17038 6966450 ECH74115_B0041 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002268424.1 16151 R 444450 CDS YP_002268425.1 209395624 6966439 complement(17038..17364) 1 NC_011350.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 17364 6966439 ECH74115_B0042 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002268425.1 17038 R 444450 CDS YP_002268426.1 209395538 6966387 complement(18675..18827) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 18827 6966387 ECH74115_B0044 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268426.1 18675 R 444450 CDS YP_002268427.1 209395633 6966381 18792..19949 1 NC_011350.1 identified by match to protein family HMM PF00376; match to protein family HMM PF01656; plasmid-partitioning protein SopA 19949 sopA 6966381 sopA Escherichia coli O157:H7 str. EC4115 plasmid-partitioning protein SopA YP_002268427.1 18792 D 444450 CDS YP_002268428.1 209395635 6966484 19949..20920 1 NC_011350.1 SopB; plasmid-partitioning protein 20920 sopB 6966484 sopB Escherichia coli O157:H7 str. EC4115 plasmid-partitioning protein YP_002268428.1 19949 D 444450 CDS YP_002268429.1 209395534 6966486 21615..22517 1 NC_011350.1 identified by match to protein family HMM PF06924; hypothetical protein 22517 6966486 ECH74115_B0048 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268429.1 21615 D 444450 CDS YP_002268430.1 209395540 6966376 complement(22468..22689) 1 NC_011350.1 hypothetical protein 22689 6966376 ECH74115_B0047 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268430.1 22468 R 444450 CDS YP_002268431.1 209395539 6966383 complement(22670..22795) 1 NC_011350.1 hypothetical protein 22795 6966383 ECH74115_B0049 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268431.1 22670 R 444450 CDS YP_002268432.1 209395564 6966382 22903..23586 1 NC_011350.1 identified by match to protein family HMM PF01555; putative methylase 23586 6966382 ECH74115_B0050 Escherichia coli O157:H7 str. EC4115 putative methylase YP_002268432.1 22903 D 444450 CDS YP_002268433.1 209395625 6966411 23587..23808 1 NC_011350.1 hypothetical protein 23808 6966411 ECH74115_B0051 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268433.1 23587 D 444450 CDS YP_002268434.1 209395554 6966476 23822..24256 1 NC_011350.1 identified by match to protein family HMM PF07128; hypothetical protein 24256 6966476 ECH74115_B0052 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268434.1 23822 D 444450 CDS YP_002268435.1 209395636 6966400 24302..25078 1 NC_011350.1 hypothetical protein 25078 6966400 ECH74115_B0053 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268435.1 24302 D 444450 CDS YP_002268436.1 209395542 6966487 complement(25208..25501) 1 NC_011350.1 hypothetical protein 25501 6966487 ECH74115_B0054 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268436.1 25208 R 444450 CDS YP_002268437.1 209395626 6966386 25496..25921 1 NC_011350.1 identified by match to protein family HMM PF03230; antirestriction protein 25921 6966386 ECH74115_B0055 Escherichia coli O157:H7 str. EC4115 antirestriction protein YP_002268437.1 25496 D 444450 CDS YP_002268438.1 209395597 6966477 25968..26390 1 NC_011350.1 hypothetical protein 26390 6966477 ECH74115_B0056 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268438.1 25968 D 444450 CDS YP_002268439.1 209395559 6966447 26387..26578 1 NC_011350.1 hypothetical protein 26578 6966447 ECH74115_B0058 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268439.1 26387 D 444450 CDS YP_002268440.1 209395630 6966443 27212..27340 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 27340 6966443 ECH74115_B0059 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268440.1 27212 D 444450 CDS YP_002268441.1 209395533 6966481 complement(27403..27552) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 27552 6966481 ECH74115_B0060 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268441.1 27403 R 444450 CDS YP_002268442.1 209395629 6966375 27574..27804 1 NC_011350.1 hypothetical protein 27804 6966375 ECH74115_B0061 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268442.1 27574 D 444450 CDS YP_002268443.1 209395615 6966480 27856..29217 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 29217 6966480 ECH74115_B0062 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268443.1 27856 D 444450 CDS YP_002268444.1 209395595 6966465 29264..29827 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 29827 6966465 ECH74115_B0063 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268444.1 29264 D 444450 CDS YP_002268445.1 209395553 6966473 30495..30656 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 30656 6966473 ECH74115_B0065 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268445.1 30495 D 444450 CDS YP_002268446.1 209395627 6966399 30682..31134 1 NC_011350.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein 31134 6966399 ECH74115_B0066 Escherichia coli O157:H7 str. EC4115 single-stranded DNA-binding protein YP_002268446.1 30682 D 444450 CDS YP_002268447.1 209395632 6966478 31191..31424 1 NC_011350.1 identified by match to protein family HMM PF06006; hypothetical protein 31424 6966478 ECH74115_B0067 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268447.1 31191 D 444450 CDS YP_002268448.1 209395612 6966483 31490..33448 1 NC_011350.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; plasmid partition protein B 33448 6966483 ECH74115_B0068 Escherichia coli O157:H7 str. EC4115 plasmid partition protein B YP_002268448.1 31490 D 444450 CDS YP_002268449.1 209395620 6966462 33503..33937 1 NC_011350.1 identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 33937 psiB 6966462 psiB Escherichia coli O157:H7 str. EC4115 plasmid SOS inhibition protein B YP_002268449.1 33503 D 444450 CDS YP_002268450.1 209395549 6966470 33934..34695 1 NC_011350.1 PsiA; plasmid SOS inhibition protein A 34695 6966470 ECH74115_B0070 Escherichia coli O157:H7 str. EC4115 plasmid SOS inhibition protein A YP_002268450.1 33934 D 444450 CDS YP_002268451.1 209395606 6966395 34927..35085 1 NC_011350.1 identified by match to protein family HMM PF01848; small toxic polypeptide 35085 hok 6966395 hok Escherichia coli O157:H7 str. EC4115 small toxic polypeptide YP_002268451.1 34927 D 444450 CDS YP_002268452.1 209395548 6966456 35267..37240 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 37240 6966456 ECH74115_B0072 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268452.1 35267 D 444450 CDS YP_002268453.1 209395603 6966405 38854..39264 1 NC_011350.1 transposase 39264 6966405 ECH74115_B0075 Escherichia coli O157:H7 str. EC4115 transposase YP_002268453.1 38854 D 444450 CDS YP_002268454.1 209395580 6966453 39533..49042 1 NC_011350.1 identified by match to protein family HMM PF04488; match to protein family HMM TIGR01586; glycosyltransferase sugar-binding region containing DXD motif family protein 49042 6966453 ECH74115_B0076 Escherichia coli O157:H7 str. EC4115 glycosyltransferase sugar-binding region containing DXD motif family protein YP_002268454.1 39533 D 444450 CDS YP_002268455.1 209395637 6966428 complement(49333..49836) 1 NC_011350.1 identified by match to protein family HMM PF01527; match to protein family HMM PF01695; putative transposase family protein 49836 6966428 ECH74115_B0077 Escherichia coli O157:H7 str. EC4115 putative transposase family protein YP_002268455.1 49333 R 444450 CDS YP_002268456.1 209395617 6966374 49983..51281 1 NC_011350.1 identified by match to protein family HMM PF07057; protein TraI 51281 6966374 ECH74115_B0079 Escherichia coli O157:H7 str. EC4115 protein TraI YP_002268456.1 49983 D 444450 CDS YP_002268457.1 209395573 6966467 51301..52047 1 NC_011350.1 identified by match to protein family HMM PF05857; match to protein family HMM TIGR02755; conjugal transfer pilus acetylation protein TraX 52047 traX 6966467 traX Escherichia coli O157:H7 str. EC4115 conjugal transfer pilus acetylation protein TraX YP_002268457.1 51301 D 444450 CDS YP_002268458.1 209395578 6966420 52106..52966 1 NC_011350.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta fold family 52966 6966420 ECH74115_B0081 Escherichia coli O157:H7 str. EC4115 hydrolase, alpha/beta fold family YP_002268458.1 52106 D 444450 CDS YP_002268459.1 209395563 6966426 52994..53629 1 NC_011350.1 identified by match to protein family HMM PF05286; conjugal transfer fertility inhibition protein FinO 53629 finO 6966426 finO Escherichia coli O157:H7 str. EC4115 conjugal transfer fertility inhibition protein FinO YP_002268459.1 52994 D 444450 CDS YP_002268460.1 209395558 6966410 53762..53974 1 NC_011350.1 hypothetical protein 53974 6966410 ECH74115_B0083 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268460.1 53762 D 444450 CDS YP_002268461.1 209395616 6966404 54219..54680 1 NC_011350.1 identified by match to protein family HMM PF00565; nuclease-like protein 54680 6966404 ECH74115_B0084 Escherichia coli O157:H7 str. EC4115 nuclease-like protein YP_002268461.1 54219 D 444450 CDS YP_002268462.1 209395610 6966466 54726..54935 1 NC_011350.1 identified by match to protein family HMM PF05321; hypothetical protein 54935 6966466 ECH74115_B0085 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268462.1 54726 D 444450 CDS YP_002268463.1 209395587 6966460 54973..55311 1 NC_011350.1 w0003 55311 6966460 ECH74115_B0086 Escherichia coli O157:H7 str. EC4115 w0003 YP_002268463.1 54973 D 444450 CDS YP_002268464.1 209395574 6966435 55551..55805 1 NC_011350.1 replication protein 55805 6966435 ECH74115_B0087 Escherichia coli O157:H7 str. EC4115 replication protein YP_002268464.1 55551 D 444450 CDS YP_002268465.1 209395532 6966489 56108..56965 1 NC_011350.1 RepA; replication protein 56965 repA 6966489 repA Escherichia coli O157:H7 str. EC4115 replication protein YP_002268465.1 56108 D 444450 CDS YP_002268466.1 209395596 6966373 complement(57040..57159) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 57159 6966373 ECH74115_B0090 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268466.1 57040 R 444450 CDS YP_002268467.1 209395552 6966446 complement(57282..57434) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 57434 6966446 ECH74115_B0091 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268467.1 57282 R 444450 CDS YP_002268468.1 209395544 6966398 57878..58162 1 NC_011350.1 identified by match to protein family HMM PF01402; CopG family protein 58162 6966398 ECH74115_B0092 Escherichia coli O157:H7 str. EC4115 CopG family protein YP_002268468.1 57878 D 444450 CDS YP_002268469.1 209395619 6966390 58162..58437 1 NC_011350.1 identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 58437 6966390 ECH74115_B0093 Escherichia coli O157:H7 str. EC4115 RelE/ParE family plasmid stabilization system protein YP_002268469.1 58162 D 444450 CDS YP_002268470.1 209395631 6966469 58532..58738 1 NC_011350.1 hypothetical protein 58738 6966469 ECH74115_B0094 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268470.1 58532 D 444450 CDS YP_002268471.1 209395560 6966482 complement(58823..59044) 1 NC_011350.1 hypothetical protein 59044 6966482 ECH74115_B0095 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268471.1 58823 R 444450 CDS YP_002268472.1 209395562 6966407 complement(59097..59831) 1 NC_011350.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; ISSd1, transposase OrfB 59831 6966407 ECH74115_B0096 Escherichia coli O157:H7 str. EC4115 ISSd1, transposase OrfB YP_002268472.1 59097 R 444450 CDS YP_002268473.1 209395530 6966409 complement(59615..60124) 1 NC_011350.1 overlaps another CDS with the same product name; transposase 60124 6966409 ECH74115_B0097 Escherichia coli O157:H7 str. EC4115 transposase YP_002268473.1 59615 R 444450 CDS YP_002268474.1 209395605 6966371 complement(60079..60264) 1 NC_011350.1 IS91, Orf2 60264 6966371 ECH74115_B0098 Escherichia coli O157:H7 str. EC4115 IS91, Orf2 YP_002268474.1 60079 R 444450 CDS YP_002268475.1 209395537 6966455 60441..62651 1 NC_011350.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 62651 katG 6966455 katG Escherichia coli O157:H7 str. EC4115 catalase/peroxidase HPI YP_002268475.1 60441 D 444450 CDS YP_002268476.1 209395604 6966380 62695..63084 1 NC_011350.1 identified by match to protein family HMM PF07361; cytochrome b562 family protein 63084 6966380 ECH74115_B0100 Escherichia coli O157:H7 str. EC4115 cytochrome b562 family protein YP_002268476.1 62695 D 444450 CDS YP_002268477.1 209395602 6966454 63090..63242 1 NC_011350.1 overlaps another CDS with the same product name; transposase OrfA 63242 6966454 ECH74115_B0101 Escherichia coli O157:H7 str. EC4115 transposase OrfA YP_002268477.1 63090 D 444450 CDS YP_002268478.1 209395561 6966452 63242..64129 1 NC_011350.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 64129 6966452 ECH74115_B0102 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002268478.1 63242 D 444450 CDS YP_002268479.1 209395607 6966408 complement(64132..64272) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 64272 6966408 ECH74115_B0103 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268479.1 64132 R 444450 CDS YP_002268480.1 209395572 6966457 64310..68212 1 NC_011350.1 identified by match to protein family HMM PF02395; match to protein family HMM PF03797; match to protein family HMM TIGR01414; immunoglobulin A1 protease domain protein 68212 6966457 ECH74115_B0104 Escherichia coli O157:H7 str. EC4115 immunoglobulin A1 protease domain protein YP_002268480.1 64310 D 444450 CDS YP_002268481.1 209395579 6966419 complement(68375..68515) 1 NC_011350.1 hypothetical protein 68515 6966419 ECH74115_B0105 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268481.1 68375 R 444450 CDS YP_002268482.1 209395577 6966427 complement(68677..68841) 1 NC_011350.1 identified by match to protein family HMM PF03811; IS1 transposase orfA 68841 6966427 ECH74115_B0106 Escherichia coli O157:H7 str. EC4115 IS1 transposase orfA YP_002268482.1 68677 R 444450 CDS YP_002268483.1 209395594 6966425 69249..69371 1 NC_011350.1 TnpA protein 69371 6966425 ECH74115_B0107 Escherichia coli O157:H7 str. EC4115 TnpA protein YP_002268483.1 69249 D 444450 CDS YP_002268484.1 209395550 6966444 complement(69544..69678) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 69678 6966444 ECH74115_B0108 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268484.1 69544 R 444450 CDS YP_002268485.1 209395536 6966379 complement(70032..70205) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 70205 6966379 ECH74115_B0110 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268485.1 70032 R 444450 CDS YP_002268486.1 209395609 6966378 70391..71212 1 NC_011350.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 71212 6966378 ECH74115_B0111 Escherichia coli O157:H7 str. EC4115 polysaccharide deacetylase family protein YP_002268486.1 70391 D 444450 CDS YP_002268487.1 209395585 6966459 71215..72318 1 NC_011350.1 identified by match to protein family HMM PF00534; UDP-sugar hydrolase 72318 6966459 ECH74115_B0112 Escherichia coli O157:H7 str. EC4115 UDP-sugar hydrolase YP_002268487.1 71215 D 444450 CDS YP_002268488.1 209395618 6966433 72408..74129 1 NC_011350.1 identified by match to protein family HMM PF00884; hypothetical protein 74129 6966433 ECH74115_B0113 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268488.1 72408 D 444450 CDS YP_002268489.1 209395556 6966468 74170..75201 1 NC_011350.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 75201 msbB 6966468 msbB Escherichia coli O157:H7 str. EC4115 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002268489.1 74170 D 444450 CDS YP_002268490.1 209395576 6966402 complement(75250..75375) 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 75375 6966402 ECH74115_B0115 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268490.1 75250 R 444450 CDS YP_002268491.1 209395622 6966424 75548..75949 1 NC_011350.1 identified by match to protein family HMM PF01527; IS66 family element, orf1 75949 6966424 ECH74115_B0116 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf1 YP_002268491.1 75548 D 444450 CDS YP_002268492.1 209395531 6966472 75946..76293 1 NC_011350.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 76293 6966472 ECH74115_B0117 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002268492.1 75946 D 444450 CDS YP_002268493.1 209395571 6966372 76343..77881 1 NC_011350.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 77881 6966372 ECH74115_B0118 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002268493.1 76343 D 444450 CDS YP_002268494.1 209395584 6966418 complement(77972..78088) 1 NC_011350.1 transposase IS3/family protein 78088 6966418 ECH74115_B0119 Escherichia coli O157:H7 str. EC4115 transposase IS3/family protein YP_002268494.1 77972 R 444450 CDS YP_002268495.1 209395569 6966432 78157..78369 1 NC_011350.1 identified by glimmer; putative; hypothetical protein 78369 6966432 ECH74115_B0120 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268495.1 78157 D 444450 CDS YP_002268496.1 209395628 6966416 78551..81247 1 NC_011350.1 hypothetical protein 81247 6966416 ECH74115_B0001 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268496.1 78551 D 444450 CDS YP_002268497.1 209395545 6966479 81334..82209 1 NC_011350.1 identified by match to protein family HMM TIGR01713; general secretion pathway protein C 82209 gspC 6966479 gspC Escherichia coli O157:H7 str. EC4115 general secretion pathway protein C YP_002268497.1 81334 D 444450 CDS YP_002268498.1 209395621 6966391 82210..84177 1 NC_011350.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517; general secretion pathway protein D 84177 gspD 6966391 gspD Escherichia coli O157:H7 str. EC4115 general secretion pathway protein D YP_002268498.1 82210 D 444450 CDS YP_002268499.1 209395608 6966471 84177..85682 1 NC_011350.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533; general secretory pathway protein E 85682 gspE 6966471 gspE Escherichia coli O157:H7 str. EC4115 general secretory pathway protein E YP_002268499.1 84177 D 444450 CDS YP_002268500.1 209395613 6966458 85684..86907 1 NC_011350.1 identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120; general secretion pathway protein F 86907 gspF 6966458 gspF Escherichia coli O157:H7 str. EC4115 general secretion pathway protein F YP_002268500.1 85684 D 444450 CDS YP_002268501.1 209395575 6966463 86938..87372 1 NC_011350.1 identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532; general secretion pathway protein G 87372 gspG 6966463 gspG Escherichia coli O157:H7 str. EC4115 general secretion pathway protein G YP_002268501.1 86938 D 444450 CDS YP_002268502.1 209395586 6966423 87369..87923 1 NC_011350.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532; general secretion pathway protein H 87923 gspH 6966423 gspH Escherichia coli O157:H7 str. EC4115 general secretion pathway protein H YP_002268502.1 87369 D 444450 CDS YP_002268503.1 209395599 6966434 87920..88285 1 NC_011350.1 identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532; general secretion pathway protein I 88285 gspI 6966434 gspI Escherichia coli O157:H7 str. EC4115 general secretion pathway protein I YP_002268503.1 87920 D 444450 CDS YP_002268504.1 209395566 6966449 88282..88881 1 NC_011350.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532; general secretion pathway protein J 88881 gspJ 6966449 gspJ Escherichia coli O157:H7 str. EC4115 general secretion pathway protein J YP_002268504.1 88282 D 444450 CDS YP_002268505.1 209395590 6966413 88878..89855 1 NC_011350.1 identified by match to protein family HMM PF03934; general secretion pathway protein K 89855 gspK 6966413 gspK Escherichia coli O157:H7 str. EC4115 general secretion pathway protein K YP_002268505.1 88878 D 444450 CDS YP_002268506.1 209395546 6966438 89927..91066 1 NC_011350.1 identified by match to protein family HMM PF05134; match to protein family HMM TIGR01709; general secretion pathway protein L 91066 gspL 6966438 gspL Escherichia coli O157:H7 str. EC4115 general secretion pathway protein L YP_002268506.1 89927 D 444450 CDS YP_002268507.1 209395623 6966392 91053..91565 1 NC_011350.1 identified by match to protein family HMM PF04612; EtpM 91565 6966392 ECH74115_B0012 Escherichia coli O157:H7 str. EC4115 EtpM YP_002268507.1 91053 D 444450 CDS YP_002268508.1 209395581 6966474 91632..92456 1 NC_011350.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; Peptidase A24 N- domain protein 92456 6966474 ECH74115_B0013 Escherichia coli O157:H7 str. EC4115 Peptidase A24 N- domain protein YP_002268508.1 91632 D 444450 CDS YP_002268509.1 209395543 6966429 92551..92949 1 NC_011350.1 identified by match to protein family HMM PF09691; match to protein family HMM TIGR01004; EptO 92949 6966429 ECH74115_B0014 Escherichia coli O157:H7 str. EC4115 EptO YP_002268509.1 92551 D 444450 CDS YP_002268510.1 209395588 6966389 93128..93433 1 NC_011350.1 identified by match to protein family HMM PF01527; IS911, transposase orfA 93433 6966389 ECH74115_B0015 Escherichia coli O157:H7 str. EC4115 IS911, transposase orfA YP_002268510.1 93128 D 444450 CDS YP_002268511.1 209395651 6966546 93..1103 1 NC_011351.1 identified by match to protein family HMM PF01051; plasmid replication protein 1103 6966546 ECH74115_A0001 Escherichia coli O157:H7 str. EC4115 plasmid replication protein YP_002268511.1 93 D 444450 CDS YP_002268512.1 209395646 6966505 1226..1495 1 NC_011351.1 hypothetical protein 1495 6966505 ECH74115_A0002 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268512.1 1226 D 444450 CDS YP_002268513.1 209395678 6966500 1624..1785 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 1785 6966500 ECH74115_A0003 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268513.1 1624 D 444450 CDS YP_002268514.1 209395682 6966532 1757..2029 1 NC_011351.1 hypothetical protein 2029 6966532 ECH74115_A0004 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268514.1 1757 D 444450 CDS YP_002268515.1 209395687 6966536 2203..2439 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 2439 6966536 ECH74115_A0005 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268515.1 2203 D 444450 CDS YP_002268516.1 209395686 6966540 2450..3451 1 NC_011351.1 identified by match to protein family HMM PF04610; conjugal transfer protein 3451 6966540 ECH74115_A0006 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein YP_002268516.1 2450 D 444450 CDS YP_002268517.1 209395663 6966539 3453..3677 1 NC_011351.1 hypothetical protein 3677 6966539 ECH74115_A0007 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268517.1 3453 D 444450 CDS YP_002268518.1 209395666 6966517 3677..4318 1 NC_011351.1 conjugal transfer protein TrbJ 4318 6966517 ECH74115_A0008 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein TrbJ YP_002268518.1 3677 D 444450 CDS YP_002268519.1 209395685 6966520 4386..4997 1 NC_011351.1 conjugal transfer protein 4997 6966520 ECH74115_A0009 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein YP_002268519.1 4386 D 444450 CDS YP_002268520.1 209395655 6966538 4990..5283 1 NC_011351.1 conjugal transfer prepropilin 5283 6966538 ECH74115_A0010 Escherichia coli O157:H7 str. EC4115 conjugal transfer prepropilin YP_002268520.1 4990 D 444450 CDS YP_002268521.1 209395642 6966509 5311..5661 1 NC_011351.1 identified by match to protein family HMM PF05101; conjugal transfer protein TraD 5661 6966509 ECH74115_A0011 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein TraD YP_002268521.1 5311 D 444450 CDS YP_002268522.1 209395648 6966496 5658..8036 1 NC_011351.1 identified by match to protein family HMM PF03135; conjugal transfer protein 8036 6966496 ECH74115_A0012 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein YP_002268522.1 5658 D 444450 CDS YP_002268523.1 209395679 6966502 8167..8904 1 NC_011351.1 identified by match to protein family HMM PF04335; conjugal transfer protein TraG 8904 6966502 ECH74115_A0013 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein TraG YP_002268523.1 8167 D 444450 CDS YP_002268524.1 209395671 6966533 8901..9680 1 NC_011351.1 identified by match to protein family HMM PF03524; conjugal transfer outer membrane protein TraH 9680 6966533 ECH74115_A0014 Escherichia coli O157:H7 str. EC4115 conjugal transfer outer membrane protein TraH YP_002268524.1 8901 D 444450 CDS YP_002268525.1 209395657 6966525 9670..10812 1 NC_011351.1 identified by match to protein family HMM PF03743; conjugal transfer protein TraI 10812 6966525 ECH74115_A0015 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein TraI YP_002268525.1 9670 D 444450 CDS YP_002268526.1 209395664 6966511 10812..11831 1 NC_011351.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02788; P-type DNA transfer ATPase VirB11 11831 virB 6966511 virB Escherichia coli O157:H7 str. EC4115 P-type DNA transfer ATPase VirB11 YP_002268526.1 10812 D 444450 CDS YP_002268527.1 209395641 6966518 11883..13850 1 NC_011351.1 identified by match to protein family HMM PF02534; conjugal transfer protein TraK 13850 6966518 ECH74115_A0017 Escherichia coli O157:H7 str. EC4115 conjugal transfer protein TraK YP_002268527.1 11883 D 444450 CDS YP_002268528.1 209395656 6966495 13866..14171 1 NC_011351.1 TrbM-domain protein 14171 6966495 ECH74115_A0018 Escherichia coli O157:H7 str. EC4115 TrbM-domain protein YP_002268528.1 13866 D 444450 CDS YP_002268529.1 209395645 6966510 14272..15894 1 NC_011351.1 repeated sequence found in lipoprotein LPP 15894 6966510 ECH74115_A0019 Escherichia coli O157:H7 str. EC4115 repeated sequence found in lipoprotein LPP YP_002268529.1 14272 D 444450 CDS YP_002268530.1 209395665 6966499 15924..16151 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 16151 6966499 ECH74115_A0020 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268530.1 15924 D 444450 CDS YP_002268531.1 209395691 6966519 16276..16863 1 NC_011351.1 hypothetical protein 16863 6966519 ECH74115_A0021 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268531.1 16276 D 444450 CDS YP_002268532.1 209395643 6966544 16875..19031 1 NC_011351.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056; DNA topoisomerase III 19031 topB 6966544 topB Escherichia coli O157:H7 str. EC4115 DNA topoisomerase III YP_002268532.1 16875 D 444450 CDS YP_002268533.1 209395688 6966497 19194..19379 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 19379 6966497 ECH74115_A0023 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268533.1 19194 D 444450 CDS YP_002268534.1 209395677 6966541 19711..20007 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 20007 6966541 ECH74115_A0024 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268534.1 19711 D 444450 CDS YP_002268535.1 209395647 6966493 21718..21933 1 NC_011351.1 putative integral membrane protein 21933 6966493 ECH74115_A0026 Escherichia coli O157:H7 str. EC4115 putative integral membrane protein YP_002268535.1 21718 D 444450 CDS YP_002268536.1 209395683 6966501 21940..22278 1 NC_011351.1 hypothetical protein 22278 6966501 ECH74115_A0028 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268536.1 21940 D 444450 CDS YP_002268537.1 209395675 6966537 complement(22258..22398) 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 22398 6966537 ECH74115_A0027 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268537.1 22258 R 444450 CDS YP_002268538.1 209395640 6966529 complement(22878..22991) 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 22991 6966529 ECH74115_A0029 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268538.1 22878 R 444450 CDS YP_002268539.1 209395653 6966494 complement(22958..23140) 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 23140 6966494 ECH74115_A0030 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268539.1 22958 R 444450 CDS YP_002268540.1 209395650 6966507 23185..24000 1 NC_011351.1 identified by match to protein family HMM PF00589; resolvase 24000 6966507 ECH74115_A0031 Escherichia coli O157:H7 str. EC4115 resolvase YP_002268540.1 23185 D 444450 CDS YP_002268541.1 209395639 6966504 24116..24775 1 NC_011351.1 putative plasmid partition protein A 24775 6966504 ECH74115_A0032 Escherichia coli O157:H7 str. EC4115 putative plasmid partition protein A YP_002268541.1 24116 D 444450 CDS YP_002268542.1 209395660 6966492 24807..25436 1 NC_011351.1 hypothetical protein 25436 6966492 ECH74115_A0033 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268542.1 24807 D 444450 CDS YP_002268543.1 209395649 6966514 25480..25782 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 25782 6966514 ECH74115_A0034 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268543.1 25480 D 444450 CDS YP_002268544.1 209395689 6966503 25818..26102 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 26102 6966503 ECH74115_A0035 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268544.1 25818 D 444450 CDS YP_002268545.1 209395692 6966542 26112..26411 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 26411 6966542 ECH74115_A0036 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268545.1 26112 D 444450 CDS YP_002268546.1 209395673 6966545 complement(26460..29657) 1 NC_011351.1 identified by match to protein family HMM PF03432; relaxase 29657 6966545 ECH74115_A0037 Escherichia coli O157:H7 str. EC4115 relaxase YP_002268546.1 26460 R 444450 CDS YP_002268547.1 209395644 6966527 complement(29654..29989) 1 NC_011351.1 identified by match to protein family HMM PF01402; relaxosome component 29989 6966527 ECH74115_A0038 Escherichia coli O157:H7 str. EC4115 relaxosome component YP_002268547.1 29654 R 444450 CDS YP_002268548.1 209395661 6966498 30335..30742 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 30742 6966498 ECH74115_A0039 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268548.1 30335 D 444450 CDS YP_002268549.1 209395690 6966515 30752..31513 1 NC_011351.1 protein TraL 31513 6966515 ECH74115_A0040 Escherichia coli O157:H7 str. EC4115 protein TraL YP_002268549.1 30752 D 444450 CDS YP_002268550.1 209395652 6966543 31510..32214 1 NC_011351.1 hypothetical protein 32214 6966543 ECH74115_A0041 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268550.1 31510 D 444450 CDS YP_002268551.1 209395659 6966506 complement(32243..32680) 1 NC_011351.1 identified by match to protein family HMM PF03681; hypothetical protein 32680 6966506 ECH74115_A0042 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268551.1 32243 R 444450 CDS YP_002268552.1 209395681 6966513 complement(32705..32887) 1 NC_011351.1 identified by match to protein family HMM PF07927; hypothetical protein 32887 6966513 ECH74115_A0043 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268552.1 32705 R 444450 CDS YP_002268553.1 209395674 6966535 complement(33110..33244) 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 33244 6966535 ECH74115_A0044 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268553.1 33110 R 444450 CDS YP_002268554.1 209395658 6966528 complement(33318..33596) 1 NC_011351.1 CcgD protein 33596 6966528 ECH74115_A0045 Escherichia coli O157:H7 str. EC4115 CcgD protein YP_002268554.1 33318 R 444450 CDS YP_002268555.1 209395654 6966512 complement(33654..33983) 1 NC_011351.1 hypothetical protein 33983 6966512 ECH74115_A0046 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268555.1 33654 R 444450 CDS YP_002268556.1 209395669 6966508 34129..34275 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 34275 6966508 ECH74115_A0047 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268556.1 34129 D 444450 CDS YP_002268557.1 209395670 6966523 complement(34421..34678) 1 NC_011351.1 YajA protein 34678 6966523 ECH74115_A0048 Escherichia coli O157:H7 str. EC4115 YajA protein YP_002268557.1 34421 R 444450 CDS YP_002268558.1 209395672 6966524 complement(34653..34919) 1 NC_011351.1 hypothetical protein 34919 6966524 ECH74115_A0049 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268558.1 34653 R 444450 CDS YP_002268559.1 209395668 6966526 complement(34970..35266) 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 35266 6966526 ECH74115_A0050 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268559.1 34970 R 444450 CDS YP_002268560.1 209395667 6966522 complement(35290..35514) 1 NC_011351.1 hypothetical protein 35514 6966522 ECH74115_A0051 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268560.1 35290 R 444450 CDS YP_002268561.1 209395676 6966521 complement(35555..35878) 1 NC_011351.1 hypothetical protein 35878 6966521 ECH74115_A0052 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268561.1 35555 R 444450 CDS YP_002268562.1 209395662 6966530 36025..36171 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 36171 6966530 ECH74115_A0053 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268562.1 36025 D 444450 CDS YP_002268563.1 209395680 6966516 36673..37026 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 37026 6966516 ECH74115_A0054 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268563.1 36673 D 444450 CDS YP_002268564.1 209395684 6966534 37252..37443 1 NC_011351.1 identified by glimmer; putative; hypothetical protein 37443 6966534 ECH74115_A0055 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268564.1 37252 D 444450 CDS YP_002268609.1 209397020 6972340 complement(133..351) 1 NC_011353.1 identified by glimmer; hypothetical protein 351 6972340 ECH74115_0001 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268609.1 133 R 444450 CDS YP_002268610.1 209398223 6967964 360..2816 1 NC_011353.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2816 thrA 6967964 thrA Escherichia coli O157:H7 str. EC4115 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002268610.1 360 D 444450 CDS YP_002268611.1 209395861 6969252 2818..3750 1 NC_011353.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3750 thrB 6969252 thrB Escherichia coli O157:H7 str. EC4115 homoserine kinase YP_002268611.1 2818 D 444450 CDS YP_002268612.1 209396634 6966720 3751..5037 1 NC_011353.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5037 thrC 6966720 thrC Escherichia coli O157:H7 str. EC4115 threonine synthase YP_002268612.1 3751 D 444450 CDS YP_002268613.1 209399918 6967554 5251..5547 1 NC_011353.1 hypothetical protein 5547 6967554 ECH74115_0006 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268613.1 5251 D 444450 CDS YP_002268614.1 209400824 6971082 complement(5700..6476) 1 NC_011353.1 identified by match to protein family HMM PF03883; hypothetical protein 6476 6971082 ECH74115_0007 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268614.1 5700 R 444450 CDS YP_002268615.1 209398740 6972052 complement(6546..7976) 1 NC_011353.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid carrier protein 7976 agcS 6972052 agcS Escherichia coli O157:H7 str. EC4115 amino acid carrier protein YP_002268615.1 6546 R 444450 CDS YP_002268616.1 209399547 6969816 8192..9208 1 NC_011353.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase B 9208 tal2 6969816 tal2 Escherichia coli O157:H7 str. EC4115 transaldolase B YP_002268616.1 8192 D 444450 CDS YP_002268617.1 209398876 6970684 9323..9910 1 NC_011353.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9910 mogA 6970684 mogA Escherichia coli O157:H7 str. EC4115 molybdenum cofactor biosynthesis protein MogA YP_002268617.1 9323 D 444450 CDS YP_002268618.1 209399611 6969962 complement(9945..10511) 1 NC_011353.1 identified by match to protein family HMM PF01184; hypothetical protein 10511 6969962 ECH74115_0011 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268618.1 9945 R 444450 CDS YP_002268619.1 209396480 6970755 complement(10660..11373) 1 NC_011353.1 identified by match to protein family HMM PF03667; hypothetical protein 11373 6970755 ECH74115_0012 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268619.1 10660 R 444450 CDS YP_002268620.1 209397112 6967392 complement(11399..11803) 1 NC_011353.1 hypothetical protein 11803 6967392 ECH74115_0013 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268620.1 11399 R 444450 CDS YP_002268621.1 209399575 6968061 12180..14096 1 NC_011353.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14096 dnaK 6968061 dnaK Escherichia coli O157:H7 str. EC4115 molecular chaperone DnaK YP_002268621.1 12180 D 444450 CDS YP_002268622.1 209399638 6970714 14185..15315 1 NC_011353.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 15315 dnaJ 6970714 dnaJ Escherichia coli O157:H7 str. EC4115 chaperone protein DnaJ YP_002268622.1 14185 D 444450 CDS YP_002268623.1 209397043 6970783 complement(15419..15571) 1 NC_011353.1 identified by match to protein family HMM PF01848; Hok/gef family protein 15571 6970783 ECH74115_0016 Escherichia coli O157:H7 str. EC4115 Hok/gef family protein YP_002268623.1 15419 R 444450 CDS YP_002268624.1 209397822 6967989 16157..17323 1 NC_011353.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 17323 nhaA 6967989 nhaA Escherichia coli O157:H7 str. EC4115 pH-dependent sodium/proton antiporter YP_002268624.1 16157 D 444450 CDS YP_002268625.1 209395876 6968813 17383..18288 1 NC_011353.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 18288 nhaR 6968813 nhaR Escherichia coli O157:H7 str. EC4115 transcriptional activator NhaR YP_002268625.1 17383 D 444450 CDS YP_002268626.1 209396625 6966740 complement(18326..18853) 1 NC_011353.1 hypothetical protein 18853 6966740 ECH74115_0019 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268626.1 18326 R 444450 CDS YP_002268627.1 209397389 6970614 complement(21762..22445) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone 22445 6970614 ECH74115_0023 Escherichia coli O157:H7 str. EC4115 pili assembly chaperone YP_002268627.1 21762 R 444450 CDS YP_002268628.1 209396234 6968355 complement(22495..23028) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 23028 6968355 ECH74115_0024 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002268628.1 22495 R 444450 CDS YP_002268629.1 209398029 6967125 complement(23330..24751) 1 NC_011353.1 identified by glimmer; hypothetical protein 24751 6967125 ECH74115_0025 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268629.1 23330 R 444450 CDS YP_002268630.1 209399727 6969042 complement(25221..25484) 1 NC_011353.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 25484 rpsT 6969042 rpsT Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S20 YP_002268630.1 25221 R 444450 CDS YP_002268631.1 209396939 6970880 25819..26760 1 NC_011353.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 26760 ribF 6970880 ribF Escherichia coli O157:H7 str. EC4115 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002268631.1 25819 D 444450 CDS YP_002268632.1 209400433 6967877 26803..29619 1 NC_011353.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 29619 ileS 6967877 ileS Escherichia coli O157:H7 str. EC4115 isoleucyl-tRNA synthetase YP_002268632.1 26803 D 444450 CDS YP_002268633.1 209399687 6971635 29619..30113 1 NC_011353.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 30113 lspA 6971635 lspA Escherichia coli O157:H7 str. EC4115 lipoprotein signal peptidase YP_002268633.1 29619 D 444450 CDS YP_002268634.1 209399254 6970837 30201..30650 1 NC_011353.1 identified by match to protein family HMM PF00254; FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase 30650 fkpB 6970837 fkpB Escherichia coli O157:H7 str. EC4115 FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase YP_002268634.1 30201 D 444450 CDS YP_002268635.1 209398644 6970368 30652..31602 1 NC_011353.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 31602 ispH 6970368 ispH Escherichia coli O157:H7 str. EC4115 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002268635.1 30652 D 444450 CDS YP_002268636.1 209400346 6969711 31668..32582 1 NC_011353.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 32582 rihC 6969711 rihC Escherichia coli O157:H7 str. EC4115 ribonucleoside hydrolase RihC YP_002268636.1 31668 D 444450 CDS YP_002268637.1 209399811 6971544 32749..33570 1 NC_011353.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 33570 dapB 6971544 dapB Escherichia coli O157:H7 str. EC4115 dihydrodipicolinate reductase YP_002268637.1 32749 D 444450 CDS YP_002268638.1 209400667 6970968 33849..33986 1 NC_011353.1 identified by glimmer; hypothetical protein 33986 6970968 ECH74115_0034 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268638.1 33849 D 444450 CDS YP_002268639.1 209399889 6971884 34026..35174 1 NC_011353.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 35174 carA 6971884 carA Escherichia coli O157:H7 str. EC4115 carbamoyl phosphate synthase small subunit YP_002268639.1 34026 D 444450 CDS YP_002268640.1 209396701 6971051 35192..38413 1 NC_011353.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 38413 carB 6971051 carB Escherichia coli O157:H7 str. EC4115 carbamoyl phosphate synthase large subunit YP_002268640.1 35192 D 444450 CDS YP_002268641.1 209396122 6967625 complement(38421..38639) 1 NC_011353.1 identified by glimmer; hypothetical protein 38639 6967625 ECH74115_0037 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268641.1 38421 R 444450 CDS YP_002268642.1 209399844 6967002 38674..39069 1 NC_011353.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 39069 caiF 6967002 caiF Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator CaiF YP_002268642.1 38674 D 444450 CDS YP_002268643.1 209396400 6971001 complement(39188..39778) 1 NC_011353.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 39778 paaY 6971001 paaY Escherichia coli O157:H7 str. EC4115 carnitine operon protein CaiE YP_002268643.1 39188 R 444450 CDS YP_002268644.1 209398425 6967307 complement(39784..40677) 1 NC_011353.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 40677 caiD 6967307 caiD Escherichia coli O157:H7 str. EC4115 carnitinyl-CoA dehydratase YP_002268644.1 39784 R 444450 CDS YP_002268645.1 209400477 6969473 complement(40678..42231) 1 NC_011353.1 identified by match to protein family HMM PF00501; crotonobetaine/carnitine-CoA ligase 42231 caiC 6969473 caiC Escherichia coli O157:H7 str. EC4115 crotonobetaine/carnitine-CoA ligase YP_002268645.1 40678 R 444450 CDS YP_002268646.1 209397439 6971682 complement(42305..43522) 1 NC_011353.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 43522 caiB 6971682 caiB Escherichia coli O157:H7 str. EC4115 crotonobetainyl-CoA:carnitine CoA-transferase YP_002268646.1 42305 R 444450 CDS YP_002268647.1 209399530 6968409 complement(43651..44793) 1 NC_011353.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 44793 caiA 6968409 caiA Escherichia coli O157:H7 str. EC4115 crotonobetainyl-CoA dehydrogenase YP_002268647.1 43651 R 444450 CDS YP_002268648.1 209399200 6970666 complement(44824..46338) 1 NC_011353.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 46338 caiT 6970666 caiT Escherichia coli O157:H7 str. EC4115 L-carnitine/gamma-butyrobetaine antiporter YP_002268648.1 44824 R 444450 CDS YP_002268649.1 209398664 6970308 46749..47582 1 NC_011353.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 47582 fixA 6970308 fixA Escherichia coli O157:H7 str. EC4115 electron transfer flavoprotein FixA YP_002268649.1 46749 D 444450 CDS YP_002268650.1 209400372 6969734 47597..48538 1 NC_011353.1 involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 48538 fixB 6969734 fixB Escherichia coli O157:H7 str. EC4115 electron transfer flavoprotein FixB YP_002268650.1 47597 D 444450 CDS YP_002268651.1 209399776 6971572 48589..49875 1 NC_011353.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 49875 fixC 6971572 fixC Escherichia coli O157:H7 str. EC4115 oxidoreductase FixC YP_002268651.1 48589 D 444450 CDS YP_002268652.1 209397556 6970932 49872..50159 1 NC_011353.1 ferredoxin-like protein FixX 50159 fixX 6970932 fixX Escherichia coli O157:H7 str. EC4115 ferredoxin-like protein FixX YP_002268652.1 49872 D 444450 CDS YP_002268653.1 209398741 6968532 50217..51548 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 51548 6968532 ECH74115_0049 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002268653.1 50217 D 444450 CDS YP_002268654.1 209400858 6969817 51656..52186 1 NC_011353.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 52186 kefF 6969817 kefF Escherichia coli O157:H7 str. EC4115 glutathione-regulated potassium-efflux system ancillary protein KefF YP_002268654.1 51656 D 444450 CDS YP_002268655.1 209399091 6972089 52179..54041 1 NC_011353.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 54041 kefC 6972089 kefC Escherichia coli O157:H7 str. EC4115 glutathione-regulated potassium-efflux system protein KefC YP_002268655.1 52179 D 444450 CDS YP_002268656.1 209395824 6970193 54122..54712 1 NC_011353.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 54712 folA 6970193 folA Escherichia coli O157:H7 str. EC4115 dihydrofolate reductase YP_002268656.1 54122 D 444450 CDS YP_002268657.1 209400574 6966681 54798..55031 1 NC_011353.1 identified by match to protein family HMM PF07362; hypothetical protein 55031 6966681 ECH74115_0053 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268657.1 54798 D 444450 CDS YP_002268658.1 209399517 6971784 55034..55348 1 NC_011353.1 identified by match to protein family HMM PF01845; CcdB protein 55348 6971784 ECH74115_0055 Escherichia coli O157:H7 str. EC4115 CcdB protein YP_002268658.1 55034 D 444450 CDS YP_002268659.1 209398997 6970653 complement(55345..56193) 1 NC_011353.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 56193 apaH 6970653 apaH Escherichia coli O157:H7 str. EC4115 diadenosine tetraphosphatase YP_002268659.1 55345 R 444450 CDS YP_002268660.1 209398324 6970096 complement(56200..56577) 1 NC_011353.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 56577 apaG 6970096 apaG Escherichia coli O157:H7 str. EC4115 ApaG protein YP_002268660.1 56200 R 444450 CDS YP_002268661.1 209397383 6969362 complement(56580..57401) 1 NC_011353.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 57401 ksgA 6969362 ksgA Escherichia coli O157:H7 str. EC4115 dimethyladenosine transferase YP_002268661.1 56580 R 444450 CDS YP_002268662.1 209399049 6968349 complement(57398..58387) 1 NC_011353.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 58387 pdxA 6968349 pdxA Escherichia coli O157:H7 str. EC4115 4-hydroxythreonine-4-phosphate dehydrogenase YP_002268662.1 57398 R 444450 CDS YP_002268663.1 209398433 6970151 complement(58387..59673) 1 NC_011353.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 59673 surA 6970151 surA Escherichia coli O157:H7 str. EC4115 peptidyl-prolyl cis-trans isomerase SurA YP_002268663.1 58387 R 444450 CDS YP_002268664.1 209398538 6969484 complement(59726..62047) 1 NC_011353.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 62047 imp 6969484 imp Escherichia coli O157:H7 str. EC4115 organic solvent tolerance protein YP_002268664.1 59726 R 444450 CDS YP_002268665.1 209400473 6969597 62335..63150 1 NC_011353.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 63150 djlA 6969597 djlA Escherichia coli O157:H7 str. EC4115 Dna-J like membrane chaperone protein YP_002268665.1 62335 D 444450 CDS YP_002268666.1 209396031 6967676 complement(64600..65259) 1 NC_011353.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 65259 6967676 ECH74115_0063 Escherichia coli O157:H7 str. EC4115 23S rRNA/tRNA pseudouridine synthase A YP_002268666.1 64600 R 444450 CDS YP_002268667.1 209397603 6966907 complement(65271..68030) 1 NC_011353.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 68030 rapA 6966907 rapA Escherichia coli O157:H7 str. EC4115 ATP-dependent helicase HepA YP_002268667.1 65271 R 444450 CDS YP_002268668.1 209398156 6968583 complement(68341..70692) 1 NC_011353.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 70692 polB 6968583 polB Escherichia coli O157:H7 str. EC4115 DNA polymerase II YP_002268668.1 68341 R 444450 CDS YP_002268669.1 209396464 6969180 complement(70767..71462) 1 NC_011353.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 71462 araD 6969180 araD Escherichia coli O157:H7 str. EC4115 L-ribulose-5-phosphate 4-epimerase YP_002268669.1 70767 R 444450 CDS YP_002268670.1 209396986 6967375 complement(71662..73164) 1 NC_011353.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 73164 araA 6967375 araA Escherichia coli O157:H7 str. EC4115 L-arabinose isomerase YP_002268670.1 71662 R 444450 CDS YP_002268671.1 209400593 6967927 complement(73175..74875) 1 NC_011353.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 74875 araB 6967927 araB Escherichia coli O157:H7 str. EC4115 ribulokinase YP_002268671.1 73175 R 444450 CDS YP_002268672.1 209395726 6971804 75163..76092 1 NC_011353.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 76092 araC 6971804 araC Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator AraC YP_002268672.1 75163 D 444450 CDS YP_002268673.1 209399499 6966581 76178..76942 1 NC_011353.1 identified by match to protein family HMM PF09335; hypothetical protein 76942 6966581 ECH74115_0070 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268673.1 76178 D 444450 CDS YP_002268674.1 209399712 6970633 complement(77029..77727) 1 NC_011353.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 77727 thiQ 6970633 thiQ Escherichia coli O157:H7 str. EC4115 thiamine transporter ATP-binding subunit YP_002268674.1 77029 R 444450 CDS YP_002268675.1 209398294 6970863 complement(77711..79321) 1 NC_011353.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 79321 thiP 6970863 thiP Escherichia coli O157:H7 str. EC4115 thiamine transporter membrane protein YP_002268675.1 77711 R 444450 CDS YP_002268676.1 209399031 6969330 complement(79297..80280) 1 NC_011353.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 80280 tbpA 6969330 tbpA Escherichia coli O157:H7 str. EC4115 thiamine transporter substrate binding subunit YP_002268676.1 79297 R 444450 CDS YP_002268677.1 209398238 6970132 80748..81221 1 NC_011353.1 hypothetical protein 81221 6970132 ECH74115_0075 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268677.1 80748 D 444450 CDS YP_002268678.1 209397844 6969269 complement(81450..83108) 1 NC_011353.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 83108 sgrR 6969269 sgrR Escherichia coli O157:H7 str. EC4115 transcriptional regulator SgrR YP_002268678.1 81450 R 444450 CDS YP_002268679.1 209397741 6972252 complement(83436..84041) 1 NC_011353.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 84041 leuD 6972252 leuD Escherichia coli O157:H7 str. EC4115 isopropylmalate isomerase small subunit YP_002268679.1 83436 R 444450 CDS YP_002268680.1 209397303 6968726 complement(84052..85452) 1 NC_011353.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 85452 leuC 6968726 leuC Escherichia coli O157:H7 str. EC4115 isopropylmalate isomerase large subunit YP_002268680.1 84052 R 444450 CDS YP_002268681.1 209399607 6968264 complement(85455..86546) 1 NC_011353.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 86546 leuB 6968264 leuB Escherichia coli O157:H7 str. EC4115 3-isopropylmalate dehydrogenase YP_002268681.1 85455 R 444450 CDS YP_002268682.1 209398496 6970749 complement(86546..88117) 1 NC_011353.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 88117 leuA 6970749 leuA Escherichia coli O157:H7 str. EC4115 2-isopropylmalate synthase YP_002268682.1 86546 R 444450 CDS YP_002268683.1 209400291 6969554 88755..88877 1 NC_011353.1 hypothetical protein 88877 6969554 ECH74115_0083 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268683.1 88755 D 444450 CDS YP_002268684.1 209396725 6971485 88954..89898 1 NC_011353.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 89898 leuO 6971485 leuO Escherichia coli O157:H7 str. EC4115 leucine transcriptional activator YP_002268684.1 88954 D 444450 CDS YP_002268685.1 209396438 6967651 complement(89934..90056) 1 NC_011353.1 identified by glimmer; hypothetical protein 90056 6967651 ECH74115_0085 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268685.1 89934 R 444450 CDS YP_002268686.1 209398207 6967348 90216..91940 1 NC_011353.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 91940 ilvI 6967348 ilvI Escherichia coli O157:H7 str. EC4115 acetolactate synthase 3 catalytic subunit YP_002268686.1 90216 D 444450 CDS YP_002268687.1 209399406 6969236 91913..92434 1 NC_011353.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 92434 ilvH 6969236 ilvH Escherichia coli O157:H7 str. EC4115 acetolactate synthase 3 regulatory subunit YP_002268687.1 91913 D 444450 CDS YP_002268688.1 209399285 6970532 92614..93618 1 NC_011353.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 93618 fruR 6970532 fruR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator FruR YP_002268688.1 92614 D 444450 CDS YP_002268689.1 209399832 6970401 94220..94678 1 NC_011353.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 94678 mraZ 6970401 mraZ Escherichia coli O157:H7 str. EC4115 cell division protein MraZ YP_002268689.1 94220 D 444450 CDS YP_002268690.1 209400403 6970989 94680..95621 1 NC_011353.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 95621 mraW 6970989 mraW Escherichia coli O157:H7 str. EC4115 S-adenosyl-methyltransferase MraW YP_002268690.1 94680 D 444450 CDS YP_002268691.1 209396379 6971604 95618..95983 1 NC_011353.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 95983 ftsL 6971604 ftsL Escherichia coli O157:H7 str. EC4115 cell division protein FtsL YP_002268691.1 95618 D 444450 CDS YP_002268692.1 209397671 6967284 95999..97765 1 NC_011353.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; peptidoglycan synthetase FtsI 97765 ftsI 6967284 ftsI Escherichia coli O157:H7 str. EC4115 peptidoglycan synthetase FtsI YP_002268692.1 95999 D 444450 CDS YP_002268693.1 209398185 6968654 97752..99239 1 NC_011353.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 99239 murE 6968654 murE Escherichia coli O157:H7 str. EC4115 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002268693.1 97752 D 444450 CDS YP_002268694.1 209398779 6969213 99236..100594 1 NC_011353.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 100594 murF 6969213 murF Escherichia coli O157:H7 str. EC4115 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002268694.1 99236 D 444450 CDS YP_002268695.1 209398077 6969857 100588..101670 1 NC_011353.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 101670 mraY 6969857 mraY Escherichia coli O157:H7 str. EC4115 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002268695.1 100588 D 444450 CDS YP_002268696.1 209398858 6969094 101673..102989 1 NC_011353.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 102989 murD 6969094 murD Escherichia coli O157:H7 str. EC4115 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002268696.1 101673 D 444450 CDS YP_002268697.1 209398089 6969943 102989..104233 1 NC_011353.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 104233 ftsW 6969943 ftsW Escherichia coli O157:H7 str. EC4115 cell division protein FtsW YP_002268697.1 102989 D 444450 CDS YP_002268698.1 209397507 6969107 104230..105297 1 NC_011353.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 105297 murG 6969107 murG Escherichia coli O157:H7 str. EC4115 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_002268698.1 104230 D 444450 CDS YP_002268699.1 209400617 6968479 105351..106826 1 NC_011353.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 106826 murC 6968479 murC Escherichia coli O157:H7 str. EC4115 UDP-N-acetylmuramate--L-alanine ligase YP_002268699.1 105351 D 444450 CDS YP_002268700.1 209399854 6971829 106819..107739 1 NC_011353.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 107739 ddl 6971829 ddl Escherichia coli O157:H7 str. EC4115 D-alanine--D-alanine ligase YP_002268700.1 106819 D 444450 CDS YP_002268701.1 209400090 6971012 107741..108571 1 NC_011353.1 involved in septum formation; cell division protein FtsQ 108571 ftsQ 6971012 ftsQ Escherichia coli O157:H7 str. EC4115 cell division protein FtsQ YP_002268701.1 107741 D 444450 CDS YP_002268702.1 209396843 6971271 108568..109830 1 NC_011353.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 109830 ftsA 6971271 ftsA Escherichia coli O157:H7 str. EC4115 cell division protein FtsA YP_002268702.1 108568 D 444450 CDS YP_002268703.1 209396274 6967776 109891..111042 1 NC_011353.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 111042 ftsZ 6967776 ftsZ Escherichia coli O157:H7 str. EC4115 cell division protein FtsZ YP_002268703.1 109891 D 444450 CDS YP_002268704.1 209397750 6967167 111143..112060 1 NC_011353.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 112060 lpxC 6967167 lpxC Escherichia coli O157:H7 str. EC4115 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002268704.1 111143 D 444450 CDS YP_002268705.1 209397161 6968737 112216..112803 1 NC_011353.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112803 secM 6968737 secM Escherichia coli O157:H7 str. EC4115 SecA regulator SecM YP_002268705.1 112216 D 444450 CDS YP_002268706.1 209399217 6968113 112865..115570 1 NC_011353.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 115570 secA 6968113 secA Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecA YP_002268706.1 112865 D 444450 CDS YP_002268707.1 209400903 6970327 115630..116028 1 NC_011353.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586; nucleoside triphosphate pyrophosphohydrolase 116028 mutT 6970327 mutT Escherichia coli O157:H7 str. EC4115 nucleoside triphosphate pyrophosphohydrolase YP_002268707.1 115630 D 444450 CDS YP_002268708.1 209400277 6972138 complement(116119..116316) 1 NC_011353.1 identified by match to protein family HMM PF03884; zinc-binding protein 116316 6972138 ECH74115_0108 Escherichia coli O157:H7 str. EC4115 zinc-binding protein YP_002268708.1 116119 R 444450 CDS YP_002268709.1 209399348 6971470 complement(116326..117069) 1 NC_011353.1 identified by match to protein family HMM PF07072; hypothetical protein 117069 6971470 ECH74115_0109 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268709.1 116326 R 444450 CDS YP_002268710.1 209398961 6970469 complement(117069..117689) 1 NC_011353.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 117689 coaE 6970469 coaE Escherichia coli O157:H7 str. EC4115 dephospho-CoA kinase YP_002268710.1 117069 R 444450 CDS YP_002268711.1 209397931 6970056 117914..118957 1 NC_011353.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 118957 guaC 6970056 guaC Escherichia coli O157:H7 str. EC4115 guanosine 5'-monophosphate oxidoreductase YP_002268711.1 117914 D 444450 CDS YP_002268712.1 209397106 6968931 complement(118992..120194) 1 NC_011353.1 identified by match to protein family HMM PF00482; type IV pilin biogenesis protein 120194 pilC 6968931 pilC Escherichia coli O157:H7 str. EC4115 type IV pilin biogenesis protein YP_002268712.1 118992 R 444450 CDS YP_002268713.1 209396061 6968055 complement(120184..121569) 1 NC_011353.1 identified by match to protein family HMM PF00437; hypothetical protein 121569 hofB 6968055 hofB Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268713.1 120184 R 444450 CDS YP_002268714.1 209396006 6966938 complement(121579..122019) 1 NC_011353.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; major pilin subunit 122019 pilA 6966938 pilA Escherichia coli O157:H7 str. EC4115 major pilin subunit YP_002268714.1 121579 R 444450 CDS YP_002268715.1 209398277 6966878 complement(122222..123115) 1 NC_011353.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 123115 nadC 6966878 nadC Escherichia coli O157:H7 str. EC4115 quinolinate phosphoribosyltransferase YP_002268715.1 122222 R 444450 CDS YP_002268716.1 209396354 6969310 123203..123754 1 NC_011353.1 identified by match to protein family HMM PF01510; N-acetyl-anhydromuranmyl-L-alanine amidase 123754 ampD 6969310 ampD Escherichia coli O157:H7 str. EC4115 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002268716.1 123203 D 444450 CDS YP_002268717.1 209399026 6967256 123751..124605 1 NC_011353.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 124605 ampE 6967256 ampE Escherichia coli O157:H7 str. EC4115 regulatory protein AmpE YP_002268717.1 123751 D 444450 CDS YP_002268718.1 209397094 6970126 complement(124648..126018) 1 NC_011353.1 identified by match to protein family HMM PF00324; aromatic amino acid transporter 126018 aroP 6970126 aroP Escherichia coli O157:H7 str. EC4115 aromatic amino acid transporter YP_002268718.1 124648 R 444450 CDS YP_002268719.1 209400019 6968042 126562..127326 1 NC_011353.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 127326 pdhR 6968042 pdhR Escherichia coli O157:H7 str. EC4115 transcriptional regulator PdhR YP_002268719.1 126562 D 444450 CDS YP_002268720.1 209399999 6971194 complement(127323..127505) 1 NC_011353.1 identified by glimmer; hypothetical protein 127505 6971194 ECH74115_0119 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268720.1 127323 R 444450 CDS YP_002268721.1 209398489 6971172 127487..130150 1 NC_011353.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 130150 aceE 6971172 aceE Escherichia coli O157:H7 str. EC4115 pyruvate dehydrogenase subunit E1 YP_002268721.1 127487 D 444450 CDS YP_002268722.1 209399253 6969546 130165..132057 1 NC_011353.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 132057 aceF 6969546 aceF Escherichia coli O157:H7 str. EC4115 dihydrolipoamide acetyltransferase YP_002268722.1 130165 D 444450 CDS YP_002268723.1 209397520 6970367 132202..133689 1 NC_011353.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 133689 lpdA 6970367 lpdA Escherichia coli O157:H7 str. EC4115 dihydrolipoamide dehydrogenase YP_002268723.1 132202 D 444450 CDS YP_002268724.1 209398273 6968493 complement(133760..135613) 1 NC_011353.1 hypothetical protein 135613 6968493 ECH74115_0124 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268724.1 133760 R 444450 CDS YP_002268725.1 209396098 6969305 135815..138565 1 NC_011353.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 138565 acnB 6969305 acnB Escherichia coli O157:H7 str. EC4115 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002268725.1 135815 D 444450 CDS YP_002268726.1 209396818 6966977 138741..139103 1 NC_011353.1 identified by match to protein family HMM PF06062; hypothetical protein 139103 6966977 ECH74115_0126 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268726.1 138741 D 444450 CDS YP_002268727.1 209397177 6967750 complement(139141..139935) 1 NC_011353.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 139935 speD 6967750 speD Escherichia coli O157:H7 str. EC4115 S-adenosylmethionine decarboxylase YP_002268727.1 139141 R 444450 CDS YP_002268728.1 209395821 6968131 complement(139951..140817) 1 NC_011353.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 140817 speE 6968131 speE Escherichia coli O157:H7 str. EC4115 spermidine synthase YP_002268728.1 139951 R 444450 CDS YP_002268729.1 209397732 6966678 complement(140923..141270) 1 NC_011353.1 hypothetical protein 141270 6966678 ECH74115_0129 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268729.1 140923 R 444450 CDS YP_002268730.1 209399964 6968717 141436..142986 1 NC_011353.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 142986 cueO 6968717 cueO Escherichia coli O157:H7 str. EC4115 multicopper oxidase YP_002268730.1 141436 D 444450 CDS YP_002268731.1 209396813 6971134 complement(143027..143164) 1 NC_011353.1 enterobactin synthetase component D 143164 6971134 ECH74115_0131 Escherichia coli O157:H7 str. EC4115 enterobactin synthetase component D YP_002268731.1 143027 R 444450 CDS YP_002268732.1 209400840 6967745 complement(143188..145578) 1 NC_011353.1 identified by match to protein family HMM PF01011; match to protein family HMM TIGR03074; quinoprotein glucose dehydrogenase 145578 gcd 6967745 gcd Escherichia coli O157:H7 str. EC4115 quinoprotein glucose dehydrogenase YP_002268732.1 143188 R 444450 CDS YP_002268733.1 209400257 6972071 145784..146320 1 NC_011353.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 146320 hpt 6972071 hpt Escherichia coli O157:H7 str. EC4115 hypoxanthine phosphoribosyltransferase YP_002268733.1 145784 D 444450 CDS YP_002268734.1 209399514 6971449 complement(146361..147023) 1 NC_011353.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 147023 can 6971449 can Escherichia coli O157:H7 str. EC4115 carbonic anhydrase YP_002268734.1 146361 R 444450 CDS YP_002268735.1 209399100 6970649 147132..148058 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 148058 6970649 ECH74115_0135 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002268735.1 147132 D 444450 CDS YP_002268736.1 209396497 6970202 148055..148825 1 NC_011353.1 identified by match to protein family HMM PF01061; ABC transporter permease 148825 6970202 ECH74115_0136 Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002268736.1 148055 D 444450 CDS YP_002268737.1 209395904 6967409 148930..149370 1 NC_011353.1 identified by match to protein family HMM PF03610; PTS system transporter subunit IIA domain-containing protein 149370 6967409 ECH74115_0137 Escherichia coli O157:H7 str. EC4115 PTS system transporter subunit IIA domain-containing protein YP_002268737.1 148930 D 444450 CDS YP_002268738.1 209396198 6966770 149434..150663 1 NC_011353.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase domain-containing protein 150663 6966770 ECH74115_0138 Escherichia coli O157:H7 str. EC4115 polysaccharide deacetylase domain-containing protein YP_002268738.1 149434 D 444450 CDS YP_002268739.1 209396925 6967085 complement(150667..151047) 1 NC_011353.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 151047 panD 6967085 panD Escherichia coli O157:H7 str. EC4115 aspartate alpha-decarboxylase YP_002268739.1 150667 R 444450 CDS YP_002268740.1 209397486 6967863 151015..151209 1 NC_011353.1 identified by glimmer; hypothetical protein 151209 6967863 ECH74115_0140 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268740.1 151015 D 444450 CDS YP_002268741.1 209398235 6968457 151321..152217 1 NC_011353.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 152217 6968457 ECH74115_0141 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268741.1 151321 D 444450 CDS YP_002268742.1 209398525 6969266 complement(152516..153367) 1 NC_011353.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 153367 panC 6969266 panC Escherichia coli O157:H7 str. EC4115 pantoate--beta-alanine ligase YP_002268742.1 152516 R 444450 CDS YP_002268743.1 209399403 6969584 complement(153379..154173) 1 NC_011353.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 154173 panB 6969584 panB Escherichia coli O157:H7 str. EC4115 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002268743.1 153379 R 444450 CDS YP_002268744.1 209396930 6970529 complement(154308..155417) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 155417 6970529 ECH74115_0144 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002268744.1 154308 R 444450 CDS YP_002268745.1 209396190 6967868 complement(155429..156019) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 156019 6967868 ECH74115_0145 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002268745.1 155429 R 444450 CDS YP_002268746.1 209395811 6967077 complement(156040..156645) 1 NC_011353.1 fimbrial protein 156645 6967077 ECH74115_0146 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002268746.1 156040 R 444450 CDS YP_002268747.1 209400978 6966667 complement(156660..157064) 1 NC_011353.1 fimbrial protein 157064 6966667 ECH74115_0147 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002268747.1 156660 R 444450 CDS YP_002268748.1 209396258 6972218 complement(157222..159822) 1 NC_011353.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 159822 6972218 ECH74115_0148 Escherichia coli O157:H7 str. EC4115 outer membrane usher protein YP_002268748.1 157222 R 444450 CDS YP_002268749.1 209396894 6967151 complement(159864..160589) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein EcpD 160589 6967151 ECH74115_0149 Escherichia coli O157:H7 str. EC4115 chaperone protein EcpD YP_002268749.1 159864 R 444450 CDS YP_002268750.1 209397435 6967832 complement(160676..161272) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 161272 6967832 ECH74115_0150 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002268750.1 160676 R 444450 CDS YP_002268751.1 209398080 6968404 complement(161553..162035) 1 NC_011353.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 162035 folK 6968404 folK Escherichia coli O157:H7 str. EC4115 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002268751.1 161553 R 444450 CDS YP_002268752.1 209398537 6969097 complement(162032..163396) 1 NC_011353.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 163396 pcnB 6969097 pcnB Escherichia coli O157:H7 str. EC4115 poly(A) polymerase I YP_002268752.1 162032 R 444450 CDS YP_002268753.1 209399179 6969596 complement(163489..164415) 1 NC_011353.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 164415 gluQ 6969596 gluQ Escherichia coli O157:H7 str. EC4115 glutamyl-Q tRNA(Asp) synthetase YP_002268753.1 163489 R 444450 CDS YP_002268754.1 209399928 6970287 complement(164452..164907) 1 NC_011353.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420; RNA polymerase-binding transcription factor 164907 dksA 6970287 dksA Escherichia coli O157:H7 str. EC4115 RNA polymerase-binding transcription factor YP_002268754.1 164452 R 444450 CDS YP_002268755.1 209400329 6971093 complement(165085..165789) 1 NC_011353.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 165789 sfsA 6971093 sfsA Escherichia coli O157:H7 str. EC4115 sugar fermentation stimulation protein A YP_002268755.1 165085 R 444450 CDS YP_002268756.1 209400335 6971525 complement(165804..166334) 1 NC_011353.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258; 2'-5' RNA ligase 166334 ligT 6971525 ligT Escherichia coli O157:H7 str. EC4115 2'-5' RNA ligase YP_002268756.1 165804 R 444450 CDS YP_002268757.1 209396555 6971532 166363..168837 1 NC_011353.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 168837 hrpB 6971532 hrpB Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase HrpB YP_002268757.1 166363 D 444450 CDS YP_002268758.1 209400125 6967469 169033..171567 1 NC_011353.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 171567 mrcB 6967469 mrcB Escherichia coli O157:H7 str. EC4115 penicillin-binding protein 1b YP_002268758.1 169033 D 444450 CDS YP_002268759.1 209398761 6971919 171787..174030 1 NC_011353.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 174030 fhuA 6971919 fhuA Escherichia coli O157:H7 str. EC4115 ferrichrome outer membrane transporter YP_002268759.1 171787 D 444450 CDS YP_002268760.1 209398510 6969839 174081..174878 1 NC_011353.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 174878 fhuC 6969839 fhuC Escherichia coli O157:H7 str. EC4115 iron-hydroxamate transporter ATP-binding subunit YP_002268760.1 174081 D 444450 CDS YP_002268761.1 209400721 6969568 174878..175768 1 NC_011353.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 175768 fhuD 6969568 fhuD Escherichia coli O157:H7 str. EC4115 iron-hydroxamate transporter substrate-binding subunit YP_002268761.1 174878 D 444450 CDS YP_002268762.1 209396292 6971945 175765..177747 1 NC_011353.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 177747 fhuB 6971945 fhuB Escherichia coli O157:H7 str. EC4115 iron-hydroxamate transporter permease subunit YP_002268762.1 175765 D 444450 CDS YP_002268763.1 209399556 6967187 complement(177782..179062) 1 NC_011353.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 179062 hemL 6967187 hemL Escherichia coli O157:H7 str. EC4115 glutamate-1-semialdehyde aminotransferase YP_002268763.1 177782 R 444450 CDS YP_002268764.1 209399766 6970694 179287..180708 1 NC_011353.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 180708 clcA 6970694 clcA Escherichia coli O157:H7 str. EC4115 chloride channel protein YP_002268764.1 179287 D 444450 CDS YP_002268765.1 209397990 6970922 180790..181134 1 NC_011353.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 181134 yadR 6970922 yadR Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster insertion protein ErpA YP_002268765.1 180790 D 444450 CDS YP_002268766.1 209399333 6969001 complement(181181..181804) 1 NC_011353.1 identified by match to protein family HMM PF03458; hypothetical protein 181804 6969001 ECH74115_0167 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268766.1 181181 R 444450 CDS YP_002268767.1 209397803 6970453 complement(181842..182642) 1 NC_011353.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 182642 btuF 6970453 btuF Escherichia coli O157:H7 str. EC4115 vitamin B12-transporter protein BtuF YP_002268767.1 181842 R 444450 CDS YP_002268768.1 209397012 6968792 complement(182635..183333) 1 NC_011353.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 183333 mtnN 6968792 mtnN Escherichia coli O157:H7 str. EC4115 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002268768.1 182635 R 444450 CDS YP_002268769.1 209396609 6967955 183417..184934 1 NC_011353.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 184934 dgt 6967955 dgt Escherichia coli O157:H7 str. EC4115 deoxyguanosinetriphosphate triphosphohydrolase YP_002268769.1 183417 D 444450 CDS YP_002268770.1 209395925 6967528 185064..186488 1 NC_011353.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 186488 degP 6967528 degP Escherichia coli O157:H7 str. EC4115 serine endoprotease YP_002268770.1 185064 D 444450 CDS YP_002268771.1 209396144 6966792 186643..187800 1 NC_011353.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 187800 cdaR 6966792 cdaR Escherichia coli O157:H7 str. EC4115 carbohydrate diacid transcriptional activator CdaR YP_002268771.1 186643 D 444450 CDS YP_002268772.1 209400953 6967027 complement(187889..188275) 1 NC_011353.1 hypothetical protein 188275 6967027 ECH74115_0173 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268772.1 187889 R 444450 CDS YP_002268773.1 209400200 6972191 complement(188590..189414) 1 NC_011353.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 189414 dapD 6972191 dapD Escherichia coli O157:H7 str. EC4115 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002268773.1 188590 R 444450 CDS YP_002268774.1 209399551 6971388 complement(189445..192117) 1 NC_011353.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 192117 glnD 6971388 glnD Escherichia coli O157:H7 str. EC4115 PII uridylyl-transferase YP_002268774.1 189445 R 444450 CDS YP_002268775.1 209398663 6970688 complement(192179..192973) 1 NC_011353.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 192973 map 6970688 map Escherichia coli O157:H7 str. EC4115 methionine aminopeptidase YP_002268775.1 192179 R 444450 CDS YP_002268776.1 209399355 6972285 193341..194066 1 NC_011353.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 194066 rpsB 6972285 rpsB Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S2 YP_002268776.1 193341 D 444450 CDS YP_002268777.1 209400468 6970476 complement(194018..194305) 1 NC_011353.1 hypothetical protein 194305 6970476 ECH74115_0178 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268777.1 194018 R 444450 CDS YP_002268778.1 209399292 6971673 194324..195175 1 NC_011353.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 195175 tsf 6971673 tsf Escherichia coli O157:H7 str. EC4115 elongation factor Ts YP_002268778.1 194324 D 444450 CDS YP_002268779.1 209397446 6970408 195322..196047 1 NC_011353.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 196047 pyrH 6970408 pyrH Escherichia coli O157:H7 str. EC4115 uridylate kinase YP_002268779.1 195322 D 444450 CDS YP_002268780.1 209398036 6968416 196197..196754 1 NC_011353.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 196754 frr 6968416 frr Escherichia coli O157:H7 str. EC4115 ribosome recycling factor YP_002268780.1 196197 D 444450 CDS YP_002268781.1 209395740 6969049 196846..198042 1 NC_011353.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 198042 dxr 6969049 dxr Escherichia coli O157:H7 str. EC4115 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002268781.1 196846 D 444450 CDS YP_002268782.1 209396854 6966595 198228..198989 1 NC_011353.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 198989 uppS 6966595 uppS Escherichia coli O157:H7 str. EC4115 undecaprenyl pyrophosphate synthase YP_002268782.1 198228 D 444450 CDS YP_002268783.1 209399460 6967788 199002..199859 1 NC_011353.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 199859 cdsA 6967788 cdsA Escherichia coli O157:H7 str. EC4115 CDP-diglyceride synthase YP_002268783.1 199002 D 444450 CDS YP_002268784.1 209399122 6970590 199871..201223 1 NC_011353.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 201223 rseP 6970590 rseP Escherichia coli O157:H7 str. EC4115 zinc metallopeptidase RseP YP_002268784.1 199871 D 444450 CDS YP_002268785.1 209400867 6970224 201253..203685 1 NC_011353.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 203685 yaeT 6970224 yaeT Escherichia coli O157:H7 str. EC4115 outer membrane protein assembly factor YaeT YP_002268785.1 201253 D 444450 CDS YP_002268786.1 209397674 6972098 203806..204291 1 NC_011353.1 identified by match to protein family HMM PF03938; periplasmic chaperone 204291 skp 6972098 skp Escherichia coli O157:H7 str. EC4115 periplasmic chaperone YP_002268786.1 203806 D 444450 CDS YP_002268787.1 209398323 6968657 204295..205320 1 NC_011353.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 205320 lpxD 6968657 lpxD Escherichia coli O157:H7 str. EC4115 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002268787.1 204295 D 444450 CDS YP_002268788.1 209396127 6969361 205425..205880 1 NC_011353.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 205880 fabZ 6969361 fabZ Escherichia coli O157:H7 str. EC4115 (3R)-hydroxymyristoyl-ACP dehydratase YP_002268788.1 205425 D 444450 CDS YP_002268789.1 209396534 6967008 205884..206672 1 NC_011353.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 206672 lpxA 6967008 lpxA Escherichia coli O157:H7 str. EC4115 UDP-N-acetylglucosamine acyltransferase YP_002268789.1 205884 D 444450 CDS YP_002268790.1 209399982 6967447 206672..207820 1 NC_011353.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 207820 lpxB 6967447 lpxB Escherichia coli O157:H7 str. EC4115 lipid-A-disaccharide synthase YP_002268790.1 206672 D 444450 CDS YP_002268791.1 209400402 6971154 207817..208413 1 NC_011353.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 208413 rnhB 6971154 rnhB Escherichia coli O157:H7 str. EC4115 ribonuclease HII YP_002268791.1 207817 D 444450 CDS YP_002268792.1 209398477 6971603 208450..211932 1 NC_011353.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 211932 dnaE 6971603 dnaE Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit alpha YP_002268792.1 208450 D 444450 CDS YP_002268793.1 209398883 6969534 211945..212904 1 NC_011353.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 212904 accA 6969534 accA Escherichia coli O157:H7 str. EC4115 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002268793.1 211945 D 444450 CDS YP_002268794.1 209400786 6969972 213003..215144 1 NC_011353.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase, constitutive 215144 ldcC1 6969972 ldcC1 Escherichia coli O157:H7 str. EC4115 lysine decarboxylase, constitutive YP_002268794.1 213003 D 444450 CDS YP_002268795.1 209396730 6972012 215201..215590 1 NC_011353.1 identified by match to protein family HMM PF00903; hypothetical protein 215590 6972012 ECH74115_0197 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268795.1 215201 D 444450 CDS YP_002268796.1 209399704 6967656 215655..216950 1 NC_011353.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 216950 tilS 6967656 tilS Escherichia coli O157:H7 str. EC4115 tRNA(Ile)-lysidine synthetase YP_002268796.1 215655 D 444450 CDS YP_002268797.1 209400475 6970854 complement(217003..217263) 1 NC_011353.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 217263 rof 6970854 rof Escherichia coli O157:H7 str. EC4115 Rho-binding antiterminator YP_002268797.1 217003 R 444450 CDS YP_002268798.1 209399141 6971680 complement(217250..217450) 1 NC_011353.1 identified by match to protein family HMM PF06786; hypothetical protein 217450 6971680 ECH74115_0200 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268798.1 217250 R 444450 CDS YP_002268799.1 209397204 6970247 217616..218161 1 NC_011353.1 identified by match to protein family HMM PF07152; hypothetical protein 218161 6970247 ECH74115_0201 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268799.1 217616 D 444450 CDS YP_002268800.1 209397979 6968160 218158..218568 1 NC_011353.1 identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein 218568 6968160 ECH74115_0202 Escherichia coli O157:H7 str. EC4115 peptidyl-tRNA hydrolase domain-containing protein YP_002268800.1 218158 D 444450 CDS YP_002268801.1 209398085 6968989 218582..219292 1 NC_011353.1 identified by match to protein family HMM PF04170; copper homeostasis and adhesion lipoprotein 219292 cutF 6968989 cutF Escherichia coli O157:H7 str. EC4115 copper homeostasis and adhesion lipoprotein YP_002268801.1 218582 D 444450 CDS YP_002268802.1 209399339 6969103 complement(219492..220316) 1 NC_011353.1 hypothetical protein 220316 6969103 ECH74115_0204 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268802.1 219492 R 444450 CDS YP_002268803.1 209398549 6970459 complement(220369..222087) 1 NC_011353.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 222087 proS 6970459 proS Escherichia coli O157:H7 str. EC4115 prolyl-tRNA synthetase YP_002268803.1 220369 R 444450 CDS YP_002268804.1 209397408 6969609 complement(222198..222905) 1 NC_011353.1 identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104; hypothetical protein 222905 6969609 ECH74115_0206 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268804.1 222198 R 444450 CDS YP_002268805.1 209397672 6968375 complement(222902..223255) 1 NC_011353.1 outer membrane lipoprotein 223255 rcsF 6968375 rcsF Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein YP_002268805.1 222902 R 444450 CDS YP_002268806.1 209400462 6968655 complement(223424..224239) 1 NC_011353.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; DL-methionine transporter substrate-binding subunit 224239 metQ 6968655 metQ Escherichia coli O157:H7 str. EC4115 DL-methionine transporter substrate-binding subunit YP_002268806.1 223424 R 444450 CDS YP_002268807.1 209399723 6971667 complement(224279..224932) 1 NC_011353.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 224932 metI 6971667 metI Escherichia coli O157:H7 str. EC4115 DL-methionine transporter permease YP_002268807.1 224279 R 444450 CDS YP_002268808.1 209399329 6970876 complement(224925..225956) 1 NC_011353.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 225956 metN 6970876 metN Escherichia coli O157:H7 str. EC4115 DL-methionine transporter ATP-binding subunit YP_002268808.1 224925 R 444450 CDS YP_002268809.1 209398642 6970449 226144..226719 1 NC_011353.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 226719 6970449 ECH74115_0211 Escherichia coli O157:H7 str. EC4115 D,D-heptose 1,7-bisphosphate phosphatase YP_002268809.1 226144 D 444450 CDS YP_002268810.1 209397612 6972360 232479..233282 1 NC_011353.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 233282 dkgB 6972360 dkgB Escherichia coli O157:H7 str. EC4115 2,5-diketo-D-gluconate reductase B YP_002268810.1 232479 D 444450 CDS YP_002268811.1 209397859 6968593 complement(233279..234193) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 234193 6968593 ECH74115_0219 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002268811.1 233279 R 444450 CDS YP_002268812.1 209396743 6968851 234434..235234 1 NC_011353.1 identified by match to protein family HMM PF03372; hypothetical protein 235234 6968851 ECH74115_0221 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268812.1 234434 D 444450 CDS YP_002268813.1 209398090 6967669 235312..236082 1 NC_011353.1 identified by match to protein family HMM PF01209; match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; UbiE/COQ5 family methyltransferase 236082 6967669 ECH74115_0222 Escherichia coli O157:H7 str. EC4115 UbiE/COQ5 family methyltransferase YP_002268813.1 235312 D 444450 CDS YP_002268814.1 209397531 6969108 complement(236130..237350) 1 NC_011353.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 237350 mltD 6969108 mltD Escherichia coli O157:H7 str. EC4115 membrane-bound lytic murein transglycosylase D YP_002268814.1 236130 R 444450 CDS YP_002268815.1 209396752 6968504 complement(237560..238315) 1 NC_011353.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 238315 gloB 6968504 gloB Escherichia coli O157:H7 str. EC4115 hydroxyacylglutathione hydrolase YP_002268815.1 237560 R 444450 CDS YP_002268816.1 209400502 6967679 238349..239071 1 NC_011353.1 identified by match to protein family HMM PF08241; methyltransferase 239071 6967679 ECH74115_0226 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002268816.1 238349 D 444450 CDS YP_002268817.1 209396174 6971707 complement(239068..239535) 1 NC_011353.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 239535 rnhA 6971707 rnhA Escherichia coli O157:H7 str. EC4115 ribonuclease H YP_002268817.1 239068 R 444450 CDS YP_002268818.1 209400894 6967060 239600..240331 1 NC_011353.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 240331 dnaQ 6967060 dnaQ Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit epsilon YP_002268818.1 239600 D 444450 CDS YP_002268819.1 209399184 6972378 240869..241669 1 NC_011353.1 hypothetical protein 241669 6972378 ECH74115_0229 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268819.1 240869 D 444450 CDS YP_002268820.1 209398597 6970292 complement(241854..242003) 1 NC_011353.1 hypothetical protein 242003 6970292 ECH74115_0230 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268820.1 241854 R 444450 CDS YP_002268821.1 209395773 6968407 complement(243962..245371) 1 NC_011353.1 identified by match to protein family HMM PF06812; ImpA domain-containing protein 245371 6968407 ECH74115_0233 Escherichia coli O157:H7 str. EC4115 ImpA domain-containing protein YP_002268821.1 243962 R 444450 CDS YP_002268822.1 209399715 6970478 complement(248953..250365) 1 NC_011353.1 identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362; ImpA domain-containing protein 250365 6970478 ECH74115_0235 Escherichia coli O157:H7 str. EC4115 ImpA domain-containing protein YP_002268822.1 248953 R 444450 CDS YP_002268823.1 209400989 6970866 complement(250370..251113) 1 NC_011353.1 identified by match to protein family HMM TIGR03360; type VI secretion-associated protein 251113 6970866 ECH74115_0236 Escherichia coli O157:H7 str. EC4115 type VI secretion-associated protein YP_002268823.1 250370 R 444450 CDS YP_002268824.1 209397886 6972231 complement(251110..253881) 1 NC_011353.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345; type VI secretion ATPase, ClpV1 family 253881 clpV 6972231 clpV Escherichia coli O157:H7 str. EC4115 type VI secretion ATPase, ClpV1 family YP_002268824.1 251110 R 444450 CDS YP_002268825.1 209395897 6968883 complement(253890..254651) 1 NC_011353.1 identified by match to protein family HMM TIGR03349; hypothetical protein 254651 6968883 ECH74115_0238 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268825.1 253890 R 444450 CDS YP_002268826.1 209398751 6966763 complement(254656..255987) 1 NC_011353.1 identified by match to protein family HMM PF05936; match to protein family HMM TIGR03353; hypothetical protein 255987 6966763 ECH74115_0239 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268826.1 254656 R 444450 CDS YP_002268827.1 209399492 6969827 complement(255990..256514) 1 NC_011353.1 identified by match to protein family HMM TIGR03352; type VI secretion lipoprotein 256514 6969827 ECH74115_0240 Escherichia coli O157:H7 str. EC4115 type VI secretion lipoprotein YP_002268827.1 255990 R 444450 CDS YP_002268828.1 209400996 6970626 complement(256511..257791) 1 NC_011353.1 identified by match to protein family HMM TIGR03354; hypothetical protein 257791 6970626 ECH74115_0241 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268828.1 256511 R 444450 CDS YP_002268829.1 209398878 6972238 complement(257816..258898) 1 NC_011353.1 identified by match to protein family HMM PF06996; match to protein family HMM TIGR03347; hypothetical protein 258898 6972238 ECH74115_0242 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268829.1 257816 R 444450 CDS YP_002268830.1 209396969 6969966 complement(258862..260712) 1 NC_011353.1 identified by match to protein family HMM PF05947; match to protein family HMM TIGR03359; hypothetical protein 260712 6969966 ECH74115_0243 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268830.1 258862 R 444450 CDS YP_002268831.1 209399977 6967909 complement(260716..261129) 1 NC_011353.1 identified by match to protein family HMM PF04965; match to protein family HMM TIGR03357; hypothetical protein 261129 6967909 ECH74115_0244 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268831.1 260716 R 444450 CDS YP_002268832.1 209395714 6971621 complement(262662..262886) 1 NC_011353.1 identified by glimmer; hypothetical protein 262886 6971621 ECH74115_0246 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268832.1 262662 R 444450 CDS YP_002268833.1 209397057 6966569 complement(262921..263421) 1 NC_011353.1 identified by match to protein family HMM PF05591; match to protein family HMM TIGR03358; hypothetical protein 263421 6966569 ECH74115_0247 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268833.1 262921 R 444450 CDS YP_002268834.1 209397620 6968003 263848..263991 1 NC_011353.1 identified by glimmer; hypothetical protein 263991 6968003 ECH74115_0248 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268834.1 263848 D 444450 CDS YP_002268835.1 209398721 6968601 264118..264636 1 NC_011353.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 264636 6968601 ECH74115_0249 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268835.1 264118 D 444450 CDS YP_002268836.1 209399507 6969793 264669..264806 1 NC_011353.1 identified by glimmer; hypothetical protein 264806 6969793 ECH74115_0250 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268836.1 264669 D 444450 CDS YP_002268837.1 209399534 6970642 264846..266987 1 NC_011353.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 266987 6970642 ECH74115_0251 Escherichia coli O157:H7 str. EC4115 ImpA family type VI secretion-associated protein YP_002268837.1 264846 D 444450 CDS YP_002268838.1 209400273 6970670 267063..271295 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 271295 6970670 ECH74115_0252 Escherichia coli O157:H7 str. EC4115 RHS Repeat family protein YP_002268838.1 267063 D 444450 CDS YP_002268839.1 209400992 6971466 271435..272151 1 NC_011353.1 identified by match to protein family HMM PF00023; ankyrin repeat-containing domain-containing protein 272151 6971466 ECH74115_0253 Escherichia coli O157:H7 str. EC4115 ankyrin repeat-containing domain-containing protein YP_002268839.1 271435 D 444450 CDS YP_002268840.1 209399453 6972234 272333..273841 1 NC_011353.1 identified by match to protein family HMM PF03527; RhsG core protein with extension 273841 6972234 ECH74115_0254 Escherichia coli O157:H7 str. EC4115 RhsG core protein with extension YP_002268840.1 272333 D 444450 CDS YP_002268841.1 209397206 6970582 273844..274467 1 NC_011353.1 hypothetical protein 274467 6970582 ECH74115_0255 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268841.1 273844 D 444450 CDS YP_002268842.1 209397982 6968163 complement(274470..274616) 1 NC_011353.1 identified by glimmer; hypothetical protein 274616 6968163 ECH74115_0256 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268842.1 274470 R 444450 CDS YP_002268843.1 209396506 6968993 275213..276349 1 NC_011353.1 identified by match to protein family HMM PF01609; ISEc3, transposase 276349 6968993 ECH74115_0257 Escherichia coli O157:H7 str. EC4115 ISEc3, transposase YP_002268843.1 275213 D 444450 CDS YP_002268844.1 209400909 6967418 276352..278112 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; RHS Repeat family protein 278112 6967418 ECH74115_0258 Escherichia coli O157:H7 str. EC4115 RHS Repeat family protein YP_002268844.1 276352 D 444450 CDS YP_002268845.1 209399210 6970548 278561..278710 1 NC_011353.1 identified by glimmer; hypothetical protein 278710 6970548 ECH74115_0261 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268845.1 278561 D 444450 CDS YP_002268846.1 209397232 6970319 278758..279930 1 NC_011353.1 identified by match to protein family HMM PF01609; transposase, IS4 family 279930 6970319 ECH74115_0262 Escherichia coli O157:H7 str. EC4115 transposase, IS4 family YP_002268846.1 278758 D 444450 CDS YP_002268847.1 209397843 6968190 complement(280048..280818) 1 NC_011353.1 identified by match to protein family HMM PF00795; hypothetical protein 280818 6968190 ECH74115_0263 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268847.1 280048 R 444450 CDS YP_002268848.1 209395742 6968835 280996..281445 1 NC_011353.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 281445 6968835 ECH74115_0264 Escherichia coli O157:H7 str. EC4115 C-lysozyme inhibitor YP_002268848.1 280996 D 444450 CDS YP_002268849.1 209397936 6966597 complement(281488..283932) 1 NC_011353.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 283932 fadE 6966597 fadE Escherichia coli O157:H7 str. EC4115 acyl-CoA dehydrogenase YP_002268849.1 281488 R 444450 CDS YP_002268850.1 209397239 6968939 284172..284750 1 NC_011353.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 284750 gmhA 6968939 gmhA Escherichia coli O157:H7 str. EC4115 phosphoheptose isomerase YP_002268850.1 284172 D 444450 CDS YP_002268851.1 209399792 6968197 284855..285622 1 NC_011353.1 identified by match to protein family HMM PF00310; glutamine amidotransferase 285622 6968197 ECH74115_0268 Escherichia coli O157:H7 str. EC4115 glutamine amidotransferase YP_002268851.1 284855 D 444450 CDS YP_002268852.1 209400375 6970949 complement(285593..286333) 1 NC_011353.1 identified by match to protein family HMM PF06104; hypothetical protein 286333 6970949 ECH74115_0267 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268852.1 285593 R 444450 CDS YP_002268853.1 209396967 6971412 complement(286768..287028) 1 NC_011353.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin component DinJ 287028 dinJ 6971412 dinJ Escherichia coli O157:H7 str. EC4115 addiction module antitoxin component DinJ YP_002268853.1 286768 R 444450 CDS YP_002268854.1 209395992 6967906 287214..287987 1 NC_011353.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 287987 6967906 ECH74115_0271 Escherichia coli O157:H7 str. EC4115 NlpC/P60 family protein YP_002268854.1 287214 D 444450 CDS YP_002268855.1 209398973 6968093 288678..288797 1 NC_011353.1 identified by glimmer; hypothetical protein 288797 6968093 ECH74115_0273 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268855.1 288678 D 444450 CDS YP_002268856.1 209397087 6970072 complement(288805..290544) 1 NC_011353.1 identified by match to protein family HMM PF00771; type III secretion protein, FHIPEP family 290544 6970072 ECH74115_0274 Escherichia coli O157:H7 str. EC4115 type III secretion protein, FHIPEP family YP_002268856.1 288805 R 444450 CDS YP_002268857.1 209397836 6968033 290504..291274 1 NC_011353.1 identified by match to protein family HMM PF00691; hypothetical protein 291274 6968033 ECH74115_0275 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268857.1 290504 D 444450 CDS YP_002268858.1 209399967 6968828 291345..292400 1 NC_011353.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 292400 dinB 6968828 dinB Escherichia coli O157:H7 str. EC4115 DNA polymerase IV YP_002268858.1 291345 D 444450 CDS YP_002268859.1 209400393 6971138 292452..292745 1 NC_011353.1 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552; antitoxin of the YafO-YafN toxin-antitoxin system 292745 6971138 ECH74115_0277 Escherichia coli O157:H7 str. EC4115 antitoxin of the YafO-YafN toxin-antitoxin system YP_002268859.1 292452 D 444450 CDS YP_002268860.1 209398666 6971594 292748..293146 1 NC_011353.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 293146 6971594 ECH74115_0278 Escherichia coli O157:H7 str. EC4115 toxin YafO YP_002268860.1 292748 D 444450 CDS YP_002268861.1 209399255 6969736 293156..293608 1 NC_011353.1 identified by match to protein family HMM PF00583; hypothetical protein 293608 6969736 ECH74115_0279 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268861.1 293156 D 444450 CDS YP_002268862.1 209397487 6970369 293927..294181 1 NC_011353.1 release factor H-coupled RctB family protein 294181 6970369 ECH74115_0280 Escherichia coli O157:H7 str. EC4115 release factor H-coupled RctB family protein YP_002268862.1 293927 D 444450 CDS YP_002268863.1 209398288 6968458 294150..294650 1 NC_011353.1 similar to release factor 1 and 2; peptide chain release factor-like protein 294650 prfH 6968458 prfH Escherichia coli O157:H7 str. EC4115 peptide chain release factor-like protein YP_002268863.1 294150 D 444450 CDS YP_002268864.1 209396193 6969322 complement(294707..296164) 1 NC_011353.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase 296164 pepD 6969322 pepD Escherichia coli O157:H7 str. EC4115 aminoacyl-histidine dipeptidase YP_002268864.1 294707 R 444450 CDS YP_002268865.1 209397752 6967080 296425..296883 1 NC_011353.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 296883 gpt 6967080 gpt Escherichia coli O157:H7 str. EC4115 xanthine-guanine phosphoribosyltransferase YP_002268865.1 296425 D 444450 CDS YP_002268866.1 209400884 6968739 296975..298219 1 NC_011353.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 298219 frsA 6968739 frsA Escherichia coli O157:H7 str. EC4115 fermentation/respiration switch protein YP_002268866.1 296975 D 444450 CDS YP_002268867.1 209400022 6972117 298277..298678 1 NC_011353.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 298678 crl 6972117 crl Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator Crl YP_002268867.1 298277 D 444450 CDS YP_002268868.1 209399294 6971197 complement(298717..299772) 1 NC_011353.1 identified by match to protein family HMM PF00267; outer membrane phosphoporin protein E 299772 phoE 6971197 phoE Escherichia coli O157:H7 str. EC4115 outer membrane phosphoporin protein E YP_002268868.1 298717 R 444450 CDS YP_002268869.1 209398531 6970410 300060..301163 1 NC_011353.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 301163 proB 6970410 proB Escherichia coli O157:H7 str. EC4115 gamma-glutamyl kinase YP_002268869.1 300060 D 444450 CDS YP_002268870.1 209397818 6969590 301175..302428 1 NC_011353.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 302428 proA 6969590 proA Escherichia coli O157:H7 str. EC4115 gamma-glutamyl phosphate reductase YP_002268870.1 301175 D 444450 CDS YP_002268871.1 209397064 6972368 complement(302633..303607) 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase 303607 6972368 ECH74115_0290 Escherichia coli O157:H7 str. EC4115 integrase YP_002268871.1 302633 R 444450 CDS YP_002268872.1 209397548 6968010 complement(304070..304960) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 304960 6968010 ECH74115_0291 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002268872.1 304070 R 444450 CDS YP_002268873.1 209396783 6968522 complement(304957..305283) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 305283 6968522 ECH74115_0292 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002268873.1 304957 R 444450 CDS YP_002268874.1 209396038 6967713 complement(305820..306533) 1 NC_011353.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381; prophage repressor 306533 6967713 ECH74115_0293 Escherichia coli O157:H7 str. EC4115 prophage repressor YP_002268874.1 305820 R 444450 CDS YP_002268875.1 209397753 6966914 306634..306834 1 NC_011353.1 identified by match to protein family HMM PF09048; hypothetical protein 306834 6966914 ECH74115_0294 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268875.1 306634 D 444450 CDS YP_002268876.1 209396320 6968740 307109..307246 1 NC_011353.1 identified by match to protein family HMM PF05269; regulatory protein CII 307246 6968740 ECH74115_0295 Escherichia coli O157:H7 str. EC4115 regulatory protein CII YP_002268876.1 307109 D 444450 CDS YP_002268877.1 209400313 6967691 308198..308509 1 NC_011353.1 replication protein P for prophage CP-933H 308509 6967691 ECH74115_0297 Escherichia coli O157:H7 str. EC4115 replication protein P for prophage CP-933H YP_002268877.1 308198 D 444450 CDS YP_002268878.1 209399869 6971509 308509..309303 1 NC_011353.1 identified by match to protein family HMM PF07484; tail fiber protein 309303 6971509 ECH74115_0298 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002268878.1 308509 D 444450 CDS YP_002268879.1 209398490 6971028 309303..309896 1 NC_011353.1 identified by match to protein family HMM PF02413; tail fiber assembly protein-like protein 309896 6971028 ECH74115_0300 Escherichia coli O157:H7 str. EC4115 tail fiber assembly protein-like protein YP_002268879.1 309303 D 444450 CDS YP_002268880.1 209398800 6969547 complement(309868..310311) 1 NC_011353.1 identified by match to protein family HMM PF02413; tail fiber assembly protein 310311 6969547 ECH74115_0299 Escherichia coli O157:H7 str. EC4115 tail fiber assembly protein YP_002268880.1 309868 R 444450 CDS YP_002268881.1 209399237 6969879 complement(310332..310742) 1 NC_011353.1 tail fiber protein 310742 6969879 ECH74115_0301 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002268881.1 310332 R 444450 CDS YP_002268882.1 209397552 6970348 310772..311326 1 NC_011353.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796; DNA-invertase 311326 6970348 ECH74115_0302 Escherichia coli O157:H7 str. EC4115 DNA-invertase YP_002268882.1 310772 D 444450 CDS YP_002268883.1 209398267 6968526 complement(311384..312157) 1 NC_011353.1 hypothetical protein 312157 6968526 ECH74115_0303 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268883.1 311384 R 444450 CDS YP_002268884.1 209399437 6969299 312981..313724 1 NC_011353.1 identified by match to protein family HMM PF00165; transcriptional regulator 313724 6969299 ECH74115_0304 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002268884.1 312981 D 444450 CDS YP_002268885.1 209397368 6970565 complement(313766..314131) 1 NC_011353.1 IS2 ORF2 314131 6970565 ECH74115_0305 Escherichia coli O157:H7 str. EC4115 IS2 ORF2 YP_002268885.1 313766 R 444450 CDS YP_002268886.1 209397533 6968335 314636..315868 1 NC_011353.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 315868 6968335 ECH74115_0306 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002268886.1 314636 D 444450 CDS YP_002268887.1 209396372 6969165 317220..317336 1 NC_011353.1 hypothetical protein 317336 6969165 ECH74115_0308 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268887.1 317220 D 444450 CDS YP_002268888.1 209398628 6971541 318581..319147 1 NC_011353.1 hypothetical protein 319147 6971541 ECH74115_0312 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268888.1 318581 D 444450 CDS YP_002268889.1 209399178 6969691 complement(319557..319679) 1 NC_011353.1 Ogr family transcription activator 319679 6969691 ECH74115_0313 Escherichia coli O157:H7 str. EC4115 Ogr family transcription activator YP_002268889.1 319557 R 444450 CDS YP_002268890.1 209399794 6970286 complement(319835..320386) 1 NC_011353.1 identified by match to protein family HMM PF07455; polarity suppression protein 320386 6970286 ECH74115_0314 Escherichia coli O157:H7 str. EC4115 polarity suppression protein YP_002268890.1 319835 R 444450 CDS YP_002268891.1 209399064 6970951 complement(320383..321135) 1 NC_011353.1 head size determination protein 321135 6970951 ECH74115_0315 Escherichia coli O157:H7 str. EC4115 head size determination protein YP_002268891.1 320383 R 444450 CDS YP_002268892.1 209398703 6970166 322069..322329 1 NC_011353.1 identified by match to protein family HMM PF05930; phage DNA binding protein 322329 6970166 ECH74115_0316 Escherichia coli O157:H7 str. EC4115 phage DNA binding protein YP_002268892.1 322069 D 444450 CDS YP_002268893.1 209398262 6969775 322551..322883 1 NC_011353.1 protein ash 322883 6969775 ECH74115_0317 Escherichia coli O157:H7 str. EC4115 protein ash YP_002268893.1 322551 D 444450 CDS YP_002268894.1 209397902 6969294 322880..323101 1 NC_011353.1 hypothetical protein 323101 6969294 ECH74115_0318 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268894.1 322880 D 444450 CDS YP_002268895.1 209396797 6968900 323101..323424 1 NC_011353.1 hypothetical protein 323424 6968900 ECH74115_0319 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268895.1 323101 D 444450 CDS YP_002268896.1 209396448 6967729 323438..325771 1 NC_011353.1 identified by match to protein family HMM PF03288; match to protein family HMM PF08273; match to protein family HMM PF08706; match to protein family HMM TIGR01613; nucleoside triphosphatase, D5 family 325771 6967729 ECH74115_0320 Escherichia coli O157:H7 str. EC4115 nucleoside triphosphatase, D5 family YP_002268896.1 323438 D 444450 CDS YP_002268897.1 209395999 6967358 complement(325904..326860) 1 NC_011353.1 hypothetical protein 326860 6967358 ECH74115_0321 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268897.1 325904 R 444450 CDS YP_002268898.1 209400952 6966871 complement(327536..328435) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 328435 6966871 ECH74115_0322 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002268898.1 327536 R 444450 CDS YP_002268899.1 209400187 6972190 328519..329256 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; clavaldehyde dehydrogenase 329256 6972190 ECH74115_0323 Escherichia coli O157:H7 str. EC4115 clavaldehyde dehydrogenase YP_002268899.1 328519 D 444450 CDS YP_002268900.1 209397126 6971374 329423..329701 1 NC_011353.1 hypothetical protein 329701 6971374 ECH74115_0324 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268900.1 329423 D 444450 CDS YP_002268901.1 209398970 6968075 329976..330125 1 NC_011353.1 hypothetical protein 330125 6968075 ECH74115_0325 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268901.1 329976 D 444450 CDS YP_002268902.1 209399565 6970067 complement(330404..331288) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR substrate binding domain-containing protein 331288 6970067 ECH74115_0326 Escherichia coli O157:H7 str. EC4115 LysR substrate binding domain-containing protein YP_002268902.1 330404 R 444450 CDS YP_002268903.1 209396830 6970703 331474..332610 1 NC_011353.1 hydrolase of the alpha/beta family protein 332610 6970703 ECH74115_0327 Escherichia coli O157:H7 str. EC4115 hydrolase of the alpha/beta family protein YP_002268903.1 331474 D 444450 CDS YP_002268904.1 209400131 6967763 332686..333879 1 NC_011353.1 identified by match to protein family HMM PF07690; purine ribonucleoside efflux pump NepI 333879 6967763 ECH74115_0328 Escherichia coli O157:H7 str. EC4115 purine ribonucleoside efflux pump NepI YP_002268904.1 332686 D 444450 CDS YP_002268905.1 209398027 6971316 complement(334058..335014) 1 NC_011353.1 identified by match to protein family HMM PF02625; xanthine dehydrogenase accessory factor 335014 6971316 ECH74115_0329 Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase accessory factor YP_002268905.1 334058 R 444450 CDS YP_002268906.1 209395976 6969040 complement(335024..337222) 1 NC_011353.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase family protein, molybdopterin-binding subunit 337222 6969040 ECH74115_0330 Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase family protein, molybdopterin-binding subunit YP_002268906.1 335024 R 444450 CDS YP_002268907.1 209398590 6966845 complement(337219..338175) 1 NC_011353.1 identified by match to protein family HMM PF00941; FAD binding domain in molybdopterin dehydrogenase 338175 6966845 ECH74115_0331 Escherichia coli O157:H7 str. EC4115 FAD binding domain in molybdopterin dehydrogenase YP_002268907.1 337219 R 444450 CDS YP_002268908.1 209399171 6969651 complement(338172..338861) 1 NC_011353.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; match to protein family HMM TIGR01409; xanthine dehydrogenase iron-sulfur-binding subunit 338861 6969651 ECH74115_0332 Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase iron-sulfur-binding subunit YP_002268908.1 338172 R 444450 CDS YP_002268909.1 209399769 6970279 339279..339893 1 NC_011353.1 identified by match to protein family HMM PF07274; hypothetical protein 339893 6970279 ECH74115_0333 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268909.1 339279 D 444450 CDS YP_002268910.1 209397316 6970925 complement(340326..340439) 1 NC_011353.1 identified by glimmer; hypothetical protein 340439 6970925 ECH74115_0334 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268910.1 340326 R 444450 CDS YP_002268911.1 209398078 6968278 complement(340783..341493) 1 NC_011353.1 hypothetical protein 341493 6968278 ECH74115_0335 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268911.1 340783 R 444450 CDS YP_002268912.1 209396118 6969095 complement(341462..343105) 1 NC_011353.1 hypothetical protein 343105 6969095 ECH74115_0336 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268912.1 341462 R 444450 CDS YP_002268913.1 209400111 6966998 complement(343095..345620) 1 NC_011353.1 hypothetical protein 345620 6966998 ECH74115_0337 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268913.1 343095 R 444450 CDS YP_002268914.1 209400874 6971294 complement(345646..346314) 1 NC_011353.1 hypothetical protein 346314 6971294 ECH74115_0338 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268914.1 345646 R 444450 CDS YP_002268915.1 209398971 6972106 complement(346372..346959) 1 NC_011353.1 fimbrillin MatB 346959 matB 6972106 matB Escherichia coli O157:H7 str. EC4115 fimbrillin MatB YP_002268915.1 346372 R 444450 CDS YP_002268916.1 209398384 6970069 complement(347034..347576) 1 NC_011353.1 identified by match to protein family HMM PF00196; fimbrillin MatA 347576 matA 6970069 matA Escherichia coli O157:H7 str. EC4115 fimbrillin MatA YP_002268916.1 347034 R 444450 CDS YP_002268917.1 209397089 6969428 complement(348662..348802) 1 NC_011353.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 348802 rpmJ 6969428 rpmJ Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L36 YP_002268917.1 348662 R 444450 CDS YP_002268918.1 209398292 6968035 complement(348802..349065) 1 NC_011353.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 349065 rpmE2 6968035 rpmE2 Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L31 YP_002268918.1 348802 R 444450 CDS YP_002268919.1 209396191 6969328 349706..350053 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 350053 6969328 ECH74115_0343 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002268919.1 349706 D 444450 CDS YP_002268920.1 209399065 6967078 350103..351641 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 351641 6967078 ECH74115_0344 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002268920.1 350103 D 444450 CDS YP_002268921.1 209400765 6970167 complement(352453..353595) 1 NC_011353.1 identified by match to protein family HMM PF00724; FAD/FMN-binding oxidoreductase 353595 6970167 ECH74115_0345 Escherichia coli O157:H7 str. EC4115 FAD/FMN-binding oxidoreductase YP_002268921.1 352453 R 444450 CDS YP_002268922.1 209399836 6971990 complement(353830..354750) 1 NC_011353.1 hypothetical protein 354750 6971990 ECH74115_0346 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268922.1 353830 R 444450 CDS YP_002268923.1 209396927 6970993 354907..355833 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 355833 6970993 ECH74115_0347 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002268923.1 354907 D 444450 CDS YP_002268924.1 209396166 6967865 complement(356121..356477) 1 NC_011353.1 hypothetical protein 356477 6967865 ECH74115_0348 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268924.1 356121 R 444450 CDS YP_002268925.1 209399148 6967050 356508..356636 1 NC_011353.1 hypothetical protein 356636 6967050 ECH74115_0349 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268925.1 356508 D 444450 CDS YP_002268926.1 209398421 6970255 complement(356670..357245) 1 NC_011353.1 identified by match to protein family HMM PF00248; morphine 6-dehydrogenase 357245 6970255 ECH74115_0350 Escherichia coli O157:H7 str. EC4115 morphine 6-dehydrogenase YP_002268926.1 356670 R 444450 CDS YP_002268927.1 209400580 6969469 357811..362064 1 NC_011353.1 identified by match to protein family HMM PF02369; invasin 362064 6969469 ECH74115_0351 Escherichia coli O157:H7 str. EC4115 invasin YP_002268927.1 357811 D 444450 CDS YP_002268928.1 209400009 6971791 complement(362185..362826) 1 NC_011353.1 identified by match to protein family HMM PF06445; AraC family transcriptional regulator 362826 6971791 ECH74115_0352 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002268928.1 362185 R 444450 CDS YP_002268929.1 209395979 6971183 363291..364160 1 NC_011353.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 364160 6971183 ECH74115_0353 Escherichia coli O157:H7 str. EC4115 oxidoreductase, aldo/keto reductase family YP_002268929.1 363291 D 444450 CDS YP_002268930.1 209395909 6966849 complement(364320..364913) 1 NC_011353.1 identified by match to protein family HMM PF04224; hypothetical protein 364913 6966849 ECH74115_0354 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268930.1 364320 R 444450 CDS YP_002268931.1 209398991 6966775 complement(364925..365161) 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 365161 6966775 ECH74115_0355 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268931.1 364925 R 444450 CDS YP_002268932.1 209399604 6970090 complement(365270..366595) 1 NC_011353.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 366595 6970090 ECH74115_0356 Escherichia coli O157:H7 str. EC4115 pyridine nucleotide-disulfide oxidoreductase YP_002268932.1 365270 R 444450 CDS YP_002268933.1 209398835 6970746 366821..367675 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 367675 6970746 ECH74115_0357 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002268933.1 366821 D 444450 CDS YP_002268934.1 209399649 6969919 complement(367834..368004) 1 NC_011353.1 identified by glimmer; hypothetical protein 368004 6969919 ECH74115_0358 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268934.1 367834 R 444450 CDS YP_002268935.1 209397003 6970794 368202..368921 1 NC_011353.1 identified by match to protein family HMM PF02754; hypothetical protein 368921 6970794 ECH74115_0359 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268935.1 368202 D 444450 CDS YP_002268936.1 209398208 6967945 368932..370359 1 NC_011353.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273; iron-sulfur cluster binding protein 370359 6967945 ECH74115_0360 Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster binding protein YP_002268936.1 368932 D 444450 CDS YP_002268937.1 209400756 6969237 370352..371047 1 NC_011353.1 identified by match to protein family HMM PF02589; hypothetical protein 371047 6969237 ECH74115_0361 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268937.1 370352 D 444450 CDS YP_002268938.1 209396270 6971981 complement(371121..371318) 1 NC_011353.1 identified by glimmer; hypothetical protein 371318 6971981 ECH74115_0362 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268938.1 371121 R 444450 CDS YP_002268939.1 209399892 6967163 371360..371497 1 NC_011353.1 identified by glimmer; hypothetical protein 371497 6967163 ECH74115_0363 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268939.1 371360 D 444450 CDS YP_002268940.1 209396540 6970593 complement(373442..373993) 1 NC_011353.1 hypothetical protein 373993 6970593 ECH74115_0367 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268940.1 373442 R 444450 CDS YP_002268941.1 209396630 6966848 complement(375033..375170) 1 NC_011353.1 hypothetical protein 375170 6966848 ECH74115_0369 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268941.1 375033 R 444450 CDS YP_002268942.1 209397028 6968777 complement(376308..376466) 1 NC_011353.1 identified by glimmer; hypothetical protein 376466 6968777 ECH74115_0372 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268942.1 376308 R 444450 CDS YP_002268943.1 209399344 6967972 complement(377103..378791) 1 NC_011353.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 378791 betA 6967972 betA Escherichia coli O157:H7 str. EC4115 choline dehydrogenase YP_002268943.1 377103 R 444450 CDS YP_002268944.1 209401007 6970465 complement(378805..380277) 1 NC_011353.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 380277 betB 6970465 betB Escherichia coli O157:H7 str. EC4115 betaine aldehyde dehydrogenase YP_002268944.1 378805 R 444450 CDS YP_002268945.1 209396409 6972249 complement(380291..380878) 1 NC_011353.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 380878 betI 6972249 betI Escherichia coli O157:H7 str. EC4115 transcriptional regulator BetI YP_002268945.1 380291 R 444450 CDS YP_002268946.1 209395783 6967316 381007..383040 1 NC_011353.1 proton-motive-force-driven choline transporter; choline transport protein BetT 383040 betT 6967316 betT Escherichia coli O157:H7 str. EC4115 choline transport protein BetT YP_002268946.1 381007 D 444450 CDS YP_002268947.1 209399058 6966639 383548..387597 1 NC_011353.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; outer membrane autotransporter 387597 6966639 ECH74115_0377 Escherichia coli O157:H7 str. EC4115 outer membrane autotransporter YP_002268947.1 383548 D 444450 CDS YP_002268948.1 209396993 6970160 387739..388827 1 NC_011353.1 identified by match to protein family HMM PF00196; match to protein family HMM PF00563; LuxR-family transcriptional regulator/cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 388827 6970160 ECH74115_0378 Escherichia coli O157:H7 str. EC4115 LuxR-family transcriptional regulator/cyclic diguanylate phosphodiesterase (EAL) domain-containing protein YP_002268948.1 387739 D 444450 CDS YP_002268949.1 209400607 6966942 390657..391262 1 NC_011353.1 identified by match to protein family HMM PF00023; ankyrin 391262 6966942 ECH74115_0382 Escherichia coli O157:H7 str. EC4115 ankyrin YP_002268949.1 390657 D 444450 CDS YP_002268950.1 209397182 6971819 391302..392165 1 NC_011353.1 hypothetical protein 392165 6971819 ECH74115_0383 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268950.1 391302 D 444450 CDS YP_002268951.1 209400839 6968136 392155..393702 1 NC_011353.1 identified by match to protein family HMM PF06263; FdrA protein 393702 6968136 ECH74115_0384 Escherichia coli O157:H7 str. EC4115 FdrA protein YP_002268951.1 392155 D 444450 CDS YP_002268952.1 209399124 6972070 393702..395120 1 NC_011353.1 identified by match to protein family HMM PF06545; hypothetical protein 395120 6972070 ECH74115_0385 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268952.1 393702 D 444450 CDS YP_002268953.1 209399553 6970226 395170..395466 1 NC_011353.1 hypothetical protein 395466 6970226 ECH74115_0386 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268953.1 395170 D 444450 CDS YP_002268954.1 209397696 6970691 395418..395603 1 NC_011353.1 hypothetical protein 395603 6970691 ECH74115_0387 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268954.1 395418 D 444450 CDS YP_002268955.1 209395980 6968679 395635..396585 1 NC_011353.1 identified by match to protein family HMM PF00696; carbamate kinase 396585 6968679 ECH74115_0388 Escherichia coli O157:H7 str. EC4115 carbamate kinase YP_002268955.1 395635 D 444450 CDS YP_002268956.1 209396661 6966850 396595..397977 1 NC_011353.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 397977 6966850 ECH74115_0389 Escherichia coli O157:H7 str. EC4115 deaminase YP_002268956.1 396595 D 444450 CDS YP_002268957.1 209400013 6967582 398246..398686 1 NC_011353.1 identified by match to protein family HMM PF04266; hypothetical protein 398686 6967582 ECH74115_0390 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268957.1 398246 D 444450 CDS YP_002268958.1 209400810 6971188 complement(398846..398962) 1 NC_011353.1 identified by glimmer; hypothetical protein 398962 6971188 ECH74115_0391 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268958.1 398846 R 444450 CDS YP_002268959.1 209398855 6972038 398937..399923 1 NC_011353.1 sugar ABC transporter substrate-binding protein 399923 6972038 ECH74115_0392 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter substrate-binding protein YP_002268959.1 398937 D 444450 CDS YP_002268960.1 209399620 6969940 399972..401456 1 NC_011353.1 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 401456 6969940 ECH74115_0393 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter ATP-binding protein YP_002268960.1 399972 D 444450 CDS YP_002268961.1 209398576 6970764 401449..402420 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF02653; sugar ABC transporter permease 402420 6970764 ECH74115_0394 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter permease YP_002268961.1 401449 D 444450 CDS YP_002268962.1 209396916 6969637 402417..403373 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF02653; sugar ABC transporter permease 403373 6969637 ECH74115_0395 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter permease YP_002268962.1 402417 D 444450 CDS YP_002268963.1 209400115 6967854 403460..404509 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 404509 6967854 ECH74115_0396 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002268963.1 403460 D 444450 CDS YP_002268964.1 209397963 6971298 404752..405567 1 NC_011353.1 hypothetical protein 405567 6971298 ECH74115_0397 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268964.1 404752 D 444450 CDS YP_002268965.1 209395748 6972334 complement(406245..406916) 1 NC_011353.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/threonine efflux protein 406916 6972334 ECH74115_0399 Escherichia coli O157:H7 str. EC4115 homoserine/threonine efflux protein YP_002268965.1 406245 R 444450 CDS YP_002268966.1 209398770 6966603 407063..407338 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 407338 6966603 ECH74115_0400 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268966.1 407063 D 444450 CDS YP_002268967.1 209400067 6969848 407365..407484 1 NC_011353.1 identified by glimmer; hypothetical protein 407484 6969848 ECH74115_0402 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268967.1 407365 D 444450 CDS YP_002268968.1 209397236 6971246 complement(407436..409022) 1 NC_011353.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329; propionate catabolism operon regulatory protein PrpR 409022 prpR 6971246 prpR Escherichia coli O157:H7 str. EC4115 propionate catabolism operon regulatory protein PrpR YP_002268968.1 407436 R 444450 CDS YP_002268969.1 209400701 6968194 409261..410151 1 NC_011353.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 410151 prpB 6968194 prpB Escherichia coli O157:H7 str. EC4115 2-methylisocitrate lyase YP_002268969.1 409261 D 444450 CDS YP_002268970.1 209395959 6971924 410307..411476 1 NC_011353.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 411476 prpC 6971924 prpC Escherichia coli O157:H7 str. EC4115 methylcitrate synthase YP_002268970.1 410307 D 444450 CDS YP_002268971.1 209398521 6966826 411510..412961 1 NC_011353.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 412961 prpD 6966826 prpD Escherichia coli O157:H7 str. EC4115 2-methylcitrate dehydratase YP_002268971.1 411510 D 444450 CDS YP_002268972.1 209395837 6969580 413001..414887 1 NC_011353.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 414887 prpE 6969580 prpE Escherichia coli O157:H7 str. EC4115 propionyl-CoA synthetase YP_002268972.1 413001 D 444450 CDS YP_002268973.1 209400583 6966694 414892..415035 1 NC_011353.1 mannitol-1-phosphate 5-dehydrogenase 415035 6966694 ECH74115_0407 Escherichia coli O157:H7 str. EC4115 mannitol-1-phosphate 5-dehydrogenase YP_002268973.1 414892 D 444450 CDS YP_002268974.1 209397539 6971794 complement(415250..415390) 1 NC_011353.1 hypothetical protein 415390 6971794 ECH74115_0408 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268974.1 415250 R 444450 CDS YP_002268975.1 209396382 6968513 415500..416759 1 NC_011353.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; cytosine permease 416759 codB 6968513 codB Escherichia coli O157:H7 str. EC4115 cytosine permease YP_002268975.1 415500 D 444450 CDS YP_002268976.1 209399439 6967287 416749..418032 1 NC_011353.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 418032 codA 6967287 codA Escherichia coli O157:H7 str. EC4115 cytosine deaminase YP_002268976.1 416749 D 444450 CDS YP_002268977.1 209398898 6970567 complement(418165..419064) 1 NC_011353.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR 419064 cynR 6970567 cynR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator CynR YP_002268977.1 418165 R 444450 CDS YP_002268978.1 209399952 6969988 419174..419833 1 NC_011353.1 identified by match to protein family HMM PF00484; carbonic anhydrase 419833 cynT 6969988 cynT Escherichia coli O157:H7 str. EC4115 carbonic anhydrase YP_002268978.1 419174 D 444450 CDS YP_002268979.1 209400023 6971120 419864..420334 1 NC_011353.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 420334 cynS 6971120 cynS Escherichia coli O157:H7 str. EC4115 cyanate hydratase YP_002268979.1 419864 D 444450 CDS YP_002268980.1 209396585 6971198 420367..421521 1 NC_011353.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; cyanate transporter 421521 cynX 6971198 cynX Escherichia coli O157:H7 str. EC4115 cyanate transporter YP_002268980.1 420367 D 444450 CDS YP_002268981.1 209399698 6967500 complement(421624..422235) 1 NC_011353.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 422235 lacA 6967500 lacA Escherichia coli O157:H7 str. EC4115 galactoside O-acetyltransferase YP_002268981.1 421624 R 444450 CDS YP_002268982.1 209400635 6970848 complement(422301..423554) 1 NC_011353.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 423554 lacY 6970848 lacY Escherichia coli O157:H7 str. EC4115 galactoside permease YP_002268982.1 422301 R 444450 CDS YP_002268983.1 209400479 6971849 complement(423606..426680) 1 NC_011353.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 426680 lacZ 6971849 lacZ Escherichia coli O157:H7 str. EC4115 beta-D-galactosidase YP_002268983.1 423606 R 444450 CDS YP_002268984.1 209395817 6971684 complement(426803..427885) 1 NC_011353.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 427885 lacI 6971684 lacI Escherichia coli O157:H7 str. EC4115 lac repressor YP_002268984.1 426803 R 444450 CDS YP_002268985.1 209396742 6966674 complement(427922..428875) 1 NC_011353.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01965; arac-family transcriptional regulator 428875 6966674 ECH74115_0419 Escherichia coli O157:H7 str. EC4115 arac-family transcriptional regulator YP_002268985.1 427922 R 444450 CDS YP_002268986.1 209397657 6967668 complement(428895..429671) 1 NC_011353.1 beta-lactamase fold protein 429671 6967668 ECH74115_0420 Escherichia coli O157:H7 str. EC4115 beta-lactamase fold protein YP_002268986.1 428895 R 444450 CDS YP_002268987.1 209397499 6968640 complement(429786..430631) 1 NC_011353.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 430631 6968640 ECH74115_0421 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator MhpR YP_002268987.1 429786 R 444450 CDS YP_002268988.1 209398053 6968471 430810..432474 1 NC_011353.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 432474 mhpA 6968471 mhpA Escherichia coli O157:H7 str. EC4115 3-(3-hydroxyphenyl)propionate hydroxylase YP_002268988.1 430810 D 444450 CDS YP_002268989.1 209399057 6969068 432476..433420 1 NC_011353.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 433420 mhpB 6969068 mhpB Escherichia coli O157:H7 str. EC4115 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_002268989.1 432476 D 444450 CDS YP_002268990.1 209399853 6970159 433438..434304 1 NC_011353.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 434304 mhpC 6970159 mhpC Escherichia coli O157:H7 str. EC4115 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_002268990.1 433438 D 444450 CDS YP_002268991.1 209399486 6971011 434314..435123 1 NC_011353.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 435123 mhpD 6971011 mhpD Escherichia coli O157:H7 str. EC4115 2-keto-4-pentenoate hydratase YP_002268991.1 434314 D 444450 CDS YP_002268992.1 209400221 6970620 435120..436070 1 NC_011353.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 436070 mhpF 6970620 mhpF Escherichia coli O157:H7 str. EC4115 acetaldehyde dehydrogenase YP_002268992.1 435120 D 444450 CDS YP_002268993.1 209398846 6971409 436067..437080 1 NC_011353.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 437080 mhpE 6971409 mhpE Escherichia coli O157:H7 str. EC4115 4-hydroxy-2-ketovalerate aldolase YP_002268993.1 436067 D 444450 CDS YP_002268994.1 209399594 6969930 437256..438467 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895; 3-hydroxyphenylpropionic transporter MhpT 438467 6969930 ECH74115_0428 Escherichia coli O157:H7 str. EC4115 3-hydroxyphenylpropionic transporter MhpT YP_002268994.1 437256 D 444450 CDS YP_002268995.1 209397080 6970735 438569..439108 1 NC_011353.1 hypothetical protein 439108 6970735 ECH74115_0429 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268995.1 438569 D 444450 CDS YP_002268996.1 209397841 6968026 complement(439233..440066) 1 NC_011353.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase 440066 fghA2 6968026 fghA2 Escherichia coli O157:H7 str. EC4115 S-formylglutathione hydrolase YP_002268996.1 439233 R 444450 CDS YP_002268997.1 209400668 6968833 complement(440159..441268) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 441268 adhC 6968833 adhC Escherichia coli O157:H7 str. EC4115 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase YP_002268997.1 440159 R 444450 CDS YP_002268998.1 209400747 6971885 complement(441303..441422) 1 NC_011353.1 hypothetical protein 441422 6971885 ECH74115_0432 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002268998.1 441303 R 444450 CDS YP_002268999.1 209398918 6971972 complement(441738..442784) 1 NC_011353.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 442784 fbpC 6971972 fbpC Escherichia coli O157:H7 str. EC4115 ferric transporter ATP-binding subunit YP_002268999.1 441738 R 444450 CDS YP_002269000.1 209399634 6970010 complement(442796..444874) 1 NC_011353.1 identified by match to protein family HMM PF00528; ABC transporter permease 444874 6970010 ECH74115_0434 Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002269000.1 442796 R 444450 CDS YP_002269001.1 209399886 6970779 complement(444943..445974) 1 NC_011353.1 identified by match to protein family HMM PF01547; family 1 extracellular solute-binding protein 445974 6970779 ECH74115_0435 Escherichia coli O157:H7 str. EC4115 family 1 extracellular solute-binding protein YP_002269001.1 444943 R 444450 CDS YP_002269002.1 209400657 6971048 complement(445971..447275) 1 NC_011353.1 identified by match to protein family HMM PF07690; regulatory protein UhpC 447275 6971048 ECH74115_0436 Escherichia coli O157:H7 str. EC4115 regulatory protein UhpC YP_002269002.1 445971 R 444450 CDS YP_002269003.1 209399895 6971873 complement(447360..448901) 1 NC_011353.1 identified by match to protein family HMM PF02518; match to protein family HMM PF05231; match to protein family HMM PF07730; integral membrane sensor signal transduction histidine kinase 448901 6971873 ECH74115_0437 Escherichia coli O157:H7 str. EC4115 integral membrane sensor signal transduction histidine kinase YP_002269003.1 447360 R 444450 CDS YP_002269004.1 209400645 6971057 complement(448901..449530) 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281; transcriptional regulatory protein UhpA 449530 6971057 ECH74115_0438 Escherichia coli O157:H7 str. EC4115 transcriptional regulatory protein UhpA YP_002269004.1 448901 R 444450 CDS YP_002269005.1 209396745 6971860 449635..449754 1 NC_011353.1 identified by glimmer; hypothetical protein 449754 6971860 ECH74115_0439 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269005.1 449635 D 444450 CDS YP_002269006.1 209397536 6967671 449833..450795 1 NC_011353.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 450795 tauA 6967671 tauA Escherichia coli O157:H7 str. EC4115 taurine transporter substrate binding subunit YP_002269006.1 449833 D 444450 CDS YP_002269007.1 209397710 6968509 450808..451575 1 NC_011353.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 451575 tauB 6968509 tauB Escherichia coli O157:H7 str. EC4115 taurine transporter ATP-binding subunit YP_002269007.1 450808 D 444450 CDS YP_002269008.1 209398897 6968694 451572..452399 1 NC_011353.1 identified by match to protein family HMM PF00528; taurine transporter subunit 452399 tauC 6968694 tauC Escherichia coli O157:H7 str. EC4115 taurine transporter subunit YP_002269008.1 451572 D 444450 CDS YP_002269009.1 209399208 6969986 452396..453247 1 NC_011353.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 453247 tauD 6969986 tauD Escherichia coli O157:H7 str. EC4115 taurine dioxygenase YP_002269009.1 452396 D 444450 CDS YP_002269010.1 209399774 6970317 complement(453354..454328) 1 NC_011353.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 454328 hemB 6970317 hemB Escherichia coli O157:H7 str. EC4115 delta-aminolevulinic acid dehydratase YP_002269010.1 453354 R 444450 CDS YP_002269011.1 209397877 6969883 457870..458493 1 NC_011353.1 identified by glimmer; DNA-binding transcriptional regulator 458493 6969883 ECH74115_0447 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002269011.1 457870 D 444450 CDS YP_002269012.1 209397433 6968873 complement(458494..459651) 1 NC_011353.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 459651 ampH 6968873 ampH Escherichia coli O157:H7 str. EC4115 beta-lactam binding protein AmpH YP_002269012.1 458494 R 444450 CDS YP_002269013.1 209395719 6968402 460003..461223 1 NC_011353.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 461223 smbA 6968402 smbA Escherichia coli O157:H7 str. EC4115 transporter YP_002269013.1 460003 D 444450 CDS YP_002269014.1 209396293 6966574 461236..462330 1 NC_011353.1 identified by match to protein family HMM PF07759; lipoprotein 462330 6966574 ECH74115_0450 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269014.1 461236 D 444450 CDS YP_002269015.1 209399900 6967188 complement(462389..462697) 1 NC_011353.1 hypothetical protein 462697 6967188 ECH74115_0451 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269015.1 462389 R 444450 CDS YP_002269016.1 209399137 6971063 462957..463169 1 NC_011353.1 hypothetical protein 463169 6971063 ECH74115_0452 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269016.1 462957 D 444450 CDS YP_002269017.1 209399711 6970241 complement(463193..464287) 1 NC_011353.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 464287 ddl 6970241 ddl Escherichia coli O157:H7 str. EC4115 D-alanyl-alanine synthetase A YP_002269017.1 463193 R 444450 CDS YP_002269018.1 209396551 6970862 464365..464568 1 NC_011353.1 identified by glimmer; hypothetical protein 464568 6970862 ECH74115_0454 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269018.1 464365 D 444450 CDS YP_002269019.1 209400905 6967465 464582..464704 1 NC_011353.1 identified by glimmer; hypothetical protein 464704 6967465 ECH74115_0455 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269019.1 464582 D 444450 CDS YP_002269020.1 209400300 6972140 464750..465010 1 NC_011353.1 hypothetical protein 465010 6972140 ECH74115_0456 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269020.1 464750 D 444450 CDS YP_002269021.1 209398220 6971494 465111..466526 1 NC_011353.1 identified by match to protein family HMM PF00245; alkaline phosphatase 466526 phoA 6971494 phoA Escherichia coli O157:H7 str. EC4115 alkaline phosphatase YP_002269021.1 465111 D 444450 CDS YP_002269022.1 209397649 6969249 466645..466965 1 NC_011353.1 identified by match to protein family HMM PF07769; hypothetical protein 466965 psiF 6969249 psiF Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269022.1 466645 D 444450 CDS YP_002269023.1 209396741 6968632 467067..468182 1 NC_011353.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 468182 adrA 6968632 adrA Escherichia coli O157:H7 str. EC4115 diguanylate cyclase AdrA YP_002269023.1 467067 D 444450 CDS YP_002269024.1 209396678 6967667 complement(468199..469008) 1 NC_011353.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 469008 proC 6967667 proC Escherichia coli O157:H7 str. EC4115 pyrroline-5-carboxylate reductase YP_002269024.1 468199 R 444450 CDS YP_002269025.1 209395936 6967599 469128..469586 1 NC_011353.1 identified by match to protein family HMM PF02639; hypothetical protein 469586 6967599 ECH74115_0461 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269025.1 469128 D 444450 CDS YP_002269026.1 209400496 6966803 469769..470293 1 NC_011353.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 470293 aroL 6966803 aroL Escherichia coli O157:H7 str. EC4115 shikimate kinase YP_002269026.1 469769 D 444450 CDS YP_002269027.1 209399697 6971701 470343..470534 1 NC_011353.1 hypothetical protein 470534 6971701 ECH74115_0463 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269027.1 470343 D 444450 CDS YP_002269028.1 209399618 6970847 470792..471469 1 NC_011353.1 identified by match to protein family HMM PF07302; hypothetical protein 471469 aroM 6970847 aroM Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269028.1 470792 D 444450 CDS YP_002269029.1 209396263 6970762 471541..471825 1 NC_011353.1 identified by match to protein family HMM PF06865; hypothetical protein 471825 6970762 ECH74115_0465 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269029.1 471541 D 444450 CDS YP_002269030.1 209400752 6967156 472083..474248 1 NC_011353.1 identified by glimmer; hypothetical protein 474248 6967156 ECH74115_0466 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269030.1 472083 D 444450 CDS YP_002269031.1 209399948 6971721 complement(474779..475690) 1 NC_011353.1 Required for efficient pilin antigenic variation; recombination associated protein 475690 rdgC 6971721 rdgC Escherichia coli O157:H7 str. EC4115 recombination associated protein YP_002269031.1 474779 R 444450 CDS YP_002269032.1 209398389 6971116 475815..476723 1 NC_011353.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 476723 mak 6971116 mak Escherichia coli O157:H7 str. EC4115 fructokinase YP_002269032.1 475815 D 444450 CDS YP_002269033.1 209397234 6969012 complement(476866..478134) 1 NC_011353.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 478134 araJ 6969012 araJ Escherichia coli O157:H7 str. EC4115 MFS transport protein AraJ YP_002269033.1 476866 R 444450 CDS YP_002269034.1 209396784 6968192 complement(478176..481319) 1 NC_011353.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 481319 sbcC 6968192 sbcC Escherichia coli O157:H7 str. EC4115 exonuclease subunit SbcC YP_002269034.1 478176 R 444450 CDS YP_002269035.1 209399959 6967715 complement(481316..482518) 1 NC_011353.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 482518 sbcD 6967715 sbcD Escherichia coli O157:H7 str. EC4115 exonuclease subunit SbcD YP_002269035.1 481316 R 444450 CDS YP_002269036.1 209399463 6971128 482504..482635 1 NC_011353.1 identified by glimmer; hypothetical protein 482635 6971128 ECH74115_0474 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269036.1 482504 D 444450 CDS YP_002269037.1 209398675 6970594 482708..483397 1 NC_011353.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 483397 phoB 6970594 phoB Escherichia coli O157:H7 str. EC4115 transcriptional regulator PhoB YP_002269037.1 482708 D 444450 CDS YP_002269038.1 209398260 6969745 483455..484750 1 NC_011353.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 484750 phoR 6969745 phoR Escherichia coli O157:H7 str. EC4115 phosphate regulon sensor protein YP_002269038.1 483455 D 444450 CDS YP_002269039.1 209397858 6969292 complement(484963..485112) 1 NC_011353.1 hypothetical protein 485112 6969292 ECH74115_0477 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269039.1 484963 R 444450 CDS YP_002269040.1 209397609 6968850 485157..486476 1 NC_011353.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 486476 brnQ 6968850 brnQ Escherichia coli O157:H7 str. EC4115 branched-chain amino acid transport system II carrier protein YP_002269040.1 485157 D 444450 CDS YP_002269041.1 209396652 6968590 486552..487925 1 NC_011353.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 487925 proY 6968590 proY Escherichia coli O157:H7 str. EC4115 proline-specific permease YP_002269041.1 486552 D 444450 CDS YP_002269042.1 209395918 6967572 488084..489898 1 NC_011353.1 identified by match to protein family HMM PF00128; maltodextrin glucosidase 489898 malZ 6967572 malZ Escherichia coli O157:H7 str. EC4115 maltodextrin glucosidase YP_002269042.1 488084 D 444450 CDS YP_002269043.1 209400742 6966785 489968..490135 1 NC_011353.1 identified by glimmer; hypothetical protein 490135 6966785 ECH74115_0481 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269043.1 489968 D 444450 CDS YP_002269044.1 209399327 6971967 complement(490196..490321) 1 NC_011353.1 identified by glimmer; hypothetical protein 490321 6971967 ECH74115_0482 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269044.1 490196 R 444450 CDS YP_002269045.1 209399535 6970447 490422..491531 1 NC_011353.1 identified by glimmer; hypothetical protein 491531 6970447 ECH74115_0483 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269045.1 490422 D 444450 CDS YP_002269046.1 209398808 6970671 complement(491552..492133) 1 NC_011353.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 492133 acpH 6970671 acpH Escherichia coli O157:H7 str. EC4115 acyl carrier protein phosphodiesterase YP_002269046.1 491552 R 444450 CDS YP_002269047.1 209400296 6969888 492226..493296 1 NC_011353.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 493296 queA 6969888 queA Escherichia coli O157:H7 str. EC4115 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002269047.1 492226 D 444450 CDS YP_002269048.1 209399464 6971490 493351..494478 1 NC_011353.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 494478 tgt 6971490 tgt Escherichia coli O157:H7 str. EC4115 queuine tRNA-ribosyltransferase YP_002269048.1 493351 D 444450 CDS YP_002269049.1 209395823 6970596 494501..494833 1 NC_011353.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 494833 yajC 6970596 yajC Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit YajC YP_002269049.1 494501 D 444450 CDS YP_002269050.1 209400898 6966680 494861..496708 1 NC_011353.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 496708 secD 6966680 secD Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecD YP_002269050.1 494861 D 444450 CDS YP_002269051.1 209396358 6972132 496719..497690 1 NC_011353.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 497690 secF 6972132 secF Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecF YP_002269051.1 496719 D 444450 CDS YP_002269052.1 209395794 6967260 497842..498084 1 NC_011353.1 identified by match to protein family HMM PF03693; match to protein family HMM TIGR02606; addiction module antidote protein 498084 6967260 ECH74115_0490 Escherichia coli O157:H7 str. EC4115 addiction module antidote protein YP_002269052.1 497842 D 444450 CDS YP_002269053.1 209397863 6966650 498077..498358 1 NC_011353.1 identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 498358 6966650 ECH74115_0491 Escherichia coli O157:H7 str. EC4115 RelE/ParE family plasmid stabilization system protein YP_002269053.1 498077 D 444450 CDS YP_002269054.1 209397193 6968855 498446..498793 1 NC_011353.1 identified by match to protein family HMM PF01844; hypothetical protein 498793 6968855 ECH74115_0492 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269054.1 498446 D 444450 CDS YP_002269055.1 209398558 6968149 complement(498970..499854) 1 NC_011353.1 identified by match to protein family HMM PF03502; nucleoside-specific channel-forming protein Tsx 499854 tsx 6968149 tsx Escherichia coli O157:H7 str. EC4115 nucleoside-specific channel-forming protein Tsx YP_002269055.1 498970 R 444450 CDS YP_002269056.1 209399296 6969618 complement(500153..500692) 1 NC_011353.1 hypothetical protein 500692 6969618 ECH74115_0494 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269056.1 500153 R 444450 CDS YP_002269057.1 209396276 6970412 500843..501292 1 NC_011353.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 501292 nrdR 6970412 nrdR Escherichia coli O157:H7 str. EC4115 transcriptional regulator NrdR YP_002269057.1 500843 D 444450 CDS YP_002269058.1 209395713 6967169 501296..502399 1 NC_011353.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 502399 ribD 6967169 ribD Escherichia coli O157:H7 str. EC4115 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_002269058.1 501296 D 444450 CDS YP_002269059.1 209400124 6966568 502488..502958 1 NC_011353.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 502958 ribH 6966568 ribH Escherichia coli O157:H7 str. EC4115 6,7-dimethyl-8-ribityllumazine synthase YP_002269059.1 502488 D 444450 CDS YP_002269060.1 209396859 6971309 502978..503397 1 NC_011353.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 503397 nusB 6971309 nusB Escherichia coli O157:H7 str. EC4115 transcription antitermination protein NusB YP_002269060.1 502978 D 444450 CDS YP_002269061.1 209398517 6967794 503475..504452 1 NC_011353.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 504452 thiL 6967794 thiL Escherichia coli O157:H7 str. EC4115 thiamine monophosphate kinase YP_002269061.1 503475 D 444450 CDS YP_002269062.1 209400639 6969576 504439..504945 1 NC_011353.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 504945 pgpA 6969576 pgpA Escherichia coli O157:H7 str. EC4115 phosphatidylglycerophosphatase A YP_002269062.1 504439 D 444450 CDS YP_002269063.1 209397011 6971853 complement(505123..506694) 1 NC_011353.1 identified by match to protein family HMM PF00805; hypothetical protein 506694 6971853 ECH74115_0501 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269063.1 505123 R 444450 CDS YP_002269064.1 209399102 6967954 complement(506925..507899) 1 NC_011353.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 507899 6967954 ECH74115_0502 Escherichia coli O157:H7 str. EC4115 oxidoreductase, aldo/keto reductase family YP_002269064.1 506925 R 444450 CDS YP_002269065.1 209398295 6970204 complement(507954..509816) 1 NC_011353.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 509816 dxs 6970204 dxs Escherichia coli O157:H7 str. EC4115 1-deoxy-D-xylulose-5-phosphate synthase YP_002269065.1 507954 R 444450 CDS YP_002269066.1 209397720 6969331 complement(509841..510740) 1 NC_011353.1 identified by match to protein family HMM PF00348; geranyltranstransferase 510740 ispA 6969331 ispA Escherichia coli O157:H7 str. EC4115 geranyltranstransferase YP_002269066.1 509841 R 444450 CDS YP_002269067.1 209398154 6968705 complement(510740..510982) 1 NC_011353.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 510982 xseB 6968705 xseB Escherichia coli O157:H7 str. EC4115 exodeoxyribonuclease VII small subunit YP_002269067.1 510740 R 444450 CDS YP_002269068.1 209396554 6969177 complement(511088..511201) 1 NC_011353.1 identified by glimmer; hypothetical protein 511201 6969177 ECH74115_0506 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269068.1 511088 R 444450 CDS YP_002269069.1 209397021 6967468 511188..512636 1 NC_011353.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 512636 thiI 6967468 thiI Escherichia coli O157:H7 str. EC4115 thiamine biosynthesis protein ThiI YP_002269069.1 511188 D 444450 CDS YP_002269070.1 209397788 6967965 complement(512690..513280) 1 NC_011353.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; DJ-1 family protein 513280 thiJ 6967965 thiJ Escherichia coli O157:H7 str. EC4115 DJ-1 family protein YP_002269070.1 512690 R 444450 CDS YP_002269071.1 209398839 6968776 complement(513243..514154) 1 NC_011353.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 514154 panE 6968776 panE Escherichia coli O157:H7 str. EC4115 2-dehydropantoate 2-reductase YP_002269071.1 513243 R 444450 CDS YP_002269072.1 209399533 6969923 514322..514813 1 NC_011353.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 514813 6969923 ECH74115_0510 Escherichia coli O157:H7 str. EC4115 nucleotide-binding protein YP_002269072.1 514322 D 444450 CDS YP_002269073.1 209400276 6970669 complement(514941..516305) 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 516305 6970669 ECH74115_0511 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002269073.1 514941 R 444450 CDS YP_002269074.1 209400803 6971469 complement(516454..517389) 1 NC_011353.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 517389 cyoE 6971469 cyoE Escherichia coli O157:H7 str. EC4115 protoheme IX farnesyltransferase YP_002269074.1 516454 R 444450 CDS YP_002269075.1 209395894 6972031 complement(517356..517685) 1 NC_011353.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02847; cytochrome o ubiquinol oxidase subunit IV 517685 cyoD 6972031 cyoD Escherichia coli O157:H7 str. EC4115 cytochrome o ubiquinol oxidase subunit IV YP_002269075.1 517356 R 444450 CDS YP_002269076.1 209396662 6966760 complement(517685..518299) 1 NC_011353.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842; cytochrome o ubiquinol oxidase subunit III 518299 cyoC 6966760 cyoC Escherichia coli O157:H7 str. EC4115 cytochrome o ubiquinol oxidase subunit III YP_002269076.1 517685 R 444450 CDS YP_002269077.1 209398374 6967583 complement(518289..520280) 1 NC_011353.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843; cytochrome o ubiquinol oxidase subunit I 520280 cyoB 6967583 cyoB Escherichia coli O157:H7 str. EC4115 cytochrome o ubiquinol oxidase subunit I YP_002269077.1 518289 R 444450 CDS YP_002269078.1 209398282 6969417 complement(520302..521249) 1 NC_011353.1 identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433; cytochrome o ubiquinol oxidase subunit II 521249 cyoA 6969417 cyoA Escherichia coli O157:H7 str. EC4115 cytochrome o ubiquinol oxidase subunit II YP_002269078.1 520302 R 444450 CDS YP_002269079.1 209400192 6969315 complement(521709..523184) 1 NC_011353.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 523184 ampG 6969315 ampG Escherichia coli O157:H7 str. EC4115 muropeptide transporter YP_002269079.1 521709 R 444450 CDS YP_002269080.1 209399405 6971379 complement(523228..523806) 1 NC_011353.1 identified by match to protein family HMM PF03923; hypothetical protein 523806 6971379 ECH74115_0518 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269080.1 523228 R 444450 CDS YP_002269081.1 209396643 6970531 complement(523856..523987) 1 NC_011353.1 identified by glimmer; hypothetical protein 523987 6970531 ECH74115_0519 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269081.1 523856 R 444450 CDS YP_002269082.1 209395922 6967563 524111..524428 1 NC_011353.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 524428 6967563 ECH74115_0520 Escherichia coli O157:H7 str. EC4115 transcriptional regulator BolA YP_002269082.1 524111 D 444450 CDS YP_002269083.1 209397869 6966789 524437..524625 1 NC_011353.1 identified by glimmer; hypothetical protein 524625 6966789 ECH74115_0521 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269083.1 524437 D 444450 CDS YP_002269084.1 209397116 6968861 524772..526070 1 NC_011353.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 526070 tig 6968861 tig Escherichia coli O157:H7 str. EC4115 trigger factor YP_002269084.1 524772 D 444450 CDS YP_002269085.1 209398902 6970141 527064..528338 1 NC_011353.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 528338 clpX 6970141 clpX Escherichia coli O157:H7 str. EC4115 ATP-dependent protease ATP-binding subunit ClpX YP_002269085.1 527064 D 444450 CDS YP_002269086.1 209399962 6969992 528481..530880 1 NC_011353.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763; DNA-binding ATP-dependent protease La 530880 lon 6969992 lon Escherichia coli O157:H7 str. EC4115 DNA-binding ATP-dependent protease La YP_002269086.1 528481 D 444450 CDS YP_002269087.1 209399224 6971132 531089..531361 1 NC_011353.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 531361 hupB 6971132 hupB Escherichia coli O157:H7 str. EC4115 transcriptional regulator HU subunit beta YP_002269087.1 531089 D 444450 CDS YP_002269088.1 209395856 6970335 531553..533424 1 NC_011353.1 identified by match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase 533424 ppiD 6970335 ppiD Escherichia coli O157:H7 str. EC4115 peptidyl-prolyl cis-trans isomerase YP_002269088.1 531553 D 444450 CDS YP_002269089.1 209400646 6966714 533575..533946 1 NC_011353.1 identified by match to protein family HMM TIGR00426; competence protein ComEA 533946 6966714 ECH74115_0528 Escherichia coli O157:H7 str. EC4115 competence protein ComEA YP_002269089.1 533575 D 444450 CDS YP_002269090.1 209396885 6971861 534052..534450 1 NC_011353.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; thioesterase family protein 534450 6971861 ECH74115_0529 Escherichia coli O157:H7 str. EC4115 thioesterase family protein YP_002269090.1 534052 D 444450 CDS YP_002269091.1 209396500 6967822 complement(534502..535197) 1 NC_011353.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 535197 queC 6967822 queC Escherichia coli O157:H7 str. EC4115 queuosine biosynthesis protein QueC YP_002269091.1 534502 R 444450 CDS YP_002269092.1 209398118 6967412 complement(535262..536962) 1 NC_011353.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein 536962 6967412 ECH74115_0531 Escherichia coli O157:H7 str. EC4115 extracellular solute-binding protein YP_002269092.1 535262 R 444450 CDS YP_002269093.1 209397377 6969137 536918..537037 1 NC_011353.1 identified by glimmer; hypothetical protein 537037 6969137 ECH74115_0532 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269093.1 536918 D 444450 CDS YP_002269094.1 209396101 6968343 537062..537880 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hydrolase Cof 537880 cof 6968343 cof Escherichia coli O157:H7 str. EC4115 hydrolase Cof YP_002269094.1 537062 D 444450 CDS YP_002269095.1 209396755 6966980 complement(537860..537985) 1 NC_011353.1 identified by glimmer; hypothetical protein 537985 6966980 ECH74115_0533 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269095.1 537860 R 444450 CDS YP_002269096.1 209397242 6967682 538032..538490 1 NC_011353.1 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 538490 6967682 ECH74115_0535 Escherichia coli O157:H7 str. EC4115 AsnC family transcriptional regulator YP_002269096.1 538032 D 444450 CDS YP_002269097.1 209397378 6968200 538520..540292 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 540292 mdlA 6968200 mdlA Escherichia coli O157:H7 str. EC4115 multidrug transporter membrane\ATP-binding components YP_002269097.1 538520 D 444450 CDS YP_002269098.1 209397292 6968344 540285..542066 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 542066 mdlB 6968344 mdlB Escherichia coli O157:H7 str. EC4115 multidrug transporter membrane\ATP-binding components YP_002269098.1 540285 D 444450 CDS YP_002269099.1 209398853 6968253 complement(542080..542220) 1 NC_011353.1 identified by glimmer; hypothetical protein 542220 6968253 ECH74115_0538 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269099.1 542080 R 444450 CDS YP_002269100.1 209400822 6969938 542247..542585 1 NC_011353.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 542585 glnK 6969938 glnK Escherichia coli O157:H7 str. EC4115 nitrogen regulatory protein P-II 2 YP_002269100.1 542247 D 444450 CDS YP_002269101.1 209399710 6972050 542615..543901 1 NC_011353.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 543901 amt 6972050 amt Escherichia coli O157:H7 str. EC4115 ammonium transporter YP_002269101.1 542615 D 444450 CDS YP_002269102.1 209396532 6970861 complement(543950..544810) 1 NC_011353.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase II 544810 tesB 6970861 tesB Escherichia coli O157:H7 str. EC4115 acyl-CoA thioesterase II YP_002269102.1 543950 R 444450 CDS YP_002269103.1 209396241 6967445 544889..545011 1 NC_011353.1 identified by glimmer; hypothetical protein 545011 6967445 ECH74115_0542 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269103.1 544889 D 444450 CDS YP_002269104.1 209398328 6967132 545043..545600 1 NC_011353.1 lipoprotein 545600 6967132 ECH74115_0543 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269104.1 545043 D 444450 CDS YP_002269105.1 209400977 6969367 complement(545633..545944) 1 NC_011353.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA-[protein]-cysteine S-methyltransferase 545944 6969367 ECH74115_0544 Escherichia coli O157:H7 str. EC4115 methylated-DNA-[protein]-cysteine S-methyltransferase YP_002269105.1 545633 R 444450 CDS YP_002269106.1 209399157 6972260 546323..546676 1 NC_011353.1 identified by match to protein family HMM PF07237; hypothetical protein 546676 6972260 ECH74115_0546 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269106.1 546323 D 444450 CDS YP_002269107.1 209400088 6970264 complement(546718..548268) 1 NC_011353.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 548268 6970264 ECH74115_0547 Escherichia coli O157:H7 str. EC4115 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein YP_002269107.1 546718 R 444450 CDS YP_002269108.1 209399987 6971269 complement(548432..548902) 1 NC_011353.1 hypothetical protein 548902 6971269 ECH74115_0548 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269108.1 548432 R 444450 CDS YP_002269109.1 209399826 6971159 complement(549018..549569) 1 NC_011353.1 identified by match to protein family HMM PF00132; maltose O-acetyltransferase 549569 maa 6971159 maa Escherichia coli O157:H7 str. EC4115 maltose O-acetyltransferase YP_002269109.1 549018 R 444450 CDS YP_002269110.1 209400347 6970983 complement(549741..549959) 1 NC_011353.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 549959 6970983 ECH74115_0550 Escherichia coli O157:H7 str. EC4115 hemolysin expression-modulating protein YP_002269110.1 549741 R 444450 CDS YP_002269111.1 209396280 6971545 complement(549985..550359) 1 NC_011353.1 hypothetical protein 550359 6971545 ECH74115_0551 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269111.1 549985 R 444450 CDS YP_002269112.1 209396368 6967174 complement(550905..554054) 1 NC_011353.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; acriflavine resistance protein B 554054 acrB 6967174 acrB Escherichia coli O157:H7 str. EC4115 acriflavine resistance protein B YP_002269112.1 550905 R 444450 CDS YP_002269113.1 209398164 6967271 complement(554077..555306) 1 NC_011353.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein A 555306 acrA 6967271 acrA Escherichia coli O157:H7 str. EC4115 acriflavine resistance protein A YP_002269113.1 554077 R 444450 CDS YP_002269114.1 209398873 6969188 555412..556059 1 NC_011353.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 556059 acrR 6969188 acrR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor AcrR YP_002269114.1 555412 D 444450 CDS YP_002269115.1 209398602 6969959 556193..559549 1 NC_011353.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 559549 kefA 6969959 kefA Escherichia coli O157:H7 str. EC4115 potassium efflux protein KefA YP_002269115.1 556193 D 444450 CDS YP_002269116.1 209400374 6969665 complement(559588..559752) 1 NC_011353.1 hypothetical protein 559752 6969665 ECH74115_0556 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269116.1 559588 R 444450 CDS YP_002269117.1 209400394 6971574 complement(559766..560293) 1 NC_011353.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 560293 priC 6971574 priC Escherichia coli O157:H7 str. EC4115 primosomal replication protein N'' YP_002269117.1 559766 R 444450 CDS YP_002269118.1 209398494 6971595 560363..560740 1 NC_011353.1 identified by match to protein family HMM PF04304; hypothetical protein 560740 6971595 ECH74115_0558 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269118.1 560363 D 444450 CDS YP_002269119.1 209398860 6969551 560893..561444 1 NC_011353.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 561444 apt 6969551 apt Escherichia coli O157:H7 str. EC4115 adenine phosphoribosyltransferase YP_002269119.1 560893 D 444450 CDS YP_002269120.1 209399465 6969946 561573..563504 1 NC_011353.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 563504 dnaX 6969946 dnaX Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunits gamma and tau YP_002269120.1 561573 D 444450 CDS YP_002269121.1 209398093 6970597 563557..563886 1 NC_011353.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 563886 6970597 ECH74115_0562 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269121.1 563557 D 444450 CDS YP_002269122.1 209396018 6969111 563886..564491 1 NC_011353.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 564491 recR 6969111 recR Escherichia coli O157:H7 str. EC4115 recombination protein RecR YP_002269122.1 563886 D 444450 CDS YP_002269123.1 209396525 6966891 564601..566475 1 NC_011353.1 molecular chaperone; heat shock protein 90 566475 htpG 6966891 htpG Escherichia coli O157:H7 str. EC4115 heat shock protein 90 YP_002269123.1 564601 D 444450 CDS YP_002269124.1 209399747 6967438 566480..566596 1 NC_011353.1 identified by glimmer; hypothetical protein 566596 6967438 ECH74115_0565 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269124.1 566480 D 444450 CDS YP_002269125.1 209397129 6970903 566596..567300 1 NC_011353.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 567300 adk 6970903 adk Escherichia coli O157:H7 str. EC4115 adenylate kinase YP_002269125.1 566596 D 444450 CDS YP_002269126.1 209400348 6968078 567432..568394 1 NC_011353.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 568394 hemH 6968078 hemH Escherichia coli O157:H7 str. EC4115 ferrochelatase YP_002269126.1 567432 D 444450 CDS YP_002269127.1 209398756 6971546 complement(568391..569350) 1 NC_011353.1 identified by match to protein family HMM PF07859; acetyl esterase 569350 aes 6971546 aes Escherichia coli O157:H7 str. EC4115 acetyl esterase YP_002269127.1 568391 R 444450 CDS YP_002269128.1 209399882 6969832 569502..570806 1 NC_011353.1 identified by match to protein family HMM PF00294; inosine kinase 570806 gsk 6969832 gsk Escherichia coli O157:H7 str. EC4115 inosine kinase YP_002269128.1 569502 D 444450 CDS YP_002269129.1 209397749 6971043 complement(570939..572615) 1 NC_011353.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 572615 6971043 ECH74115_0570 Escherichia coli O157:H7 str. EC4115 cation:proton antiport protein YP_002269129.1 570939 R 444450 CDS YP_002269130.1 209398321 6968736 complement(572852..574072) 1 NC_011353.1 identified by match to protein family HMM PF07690; fosmidomycin resistance protein 574072 fsr 6968736 fsr Escherichia coli O157:H7 str. EC4115 fosmidomycin resistance protein YP_002269130.1 572852 R 444450 CDS YP_002269131.1 209397585 6969359 574290..575942 1 NC_011353.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 575942 ushA 6969359 ushA Escherichia coli O157:H7 str. EC4115 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_002269131.1 574290 D 444450 CDS YP_002269132.1 209399446 6968563 complement(575979..576458) 1 NC_011353.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011; hypothetical protein 576458 6968563 ECH74115_0573 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269132.1 575979 R 444450 CDS YP_002269133.1 209398745 6972294 complement(576662..577456) 1 NC_011353.1 identified by match to protein family HMM PF07446; GumN family protein 577456 6972294 ECH74115_0574 Escherichia coli O157:H7 str. EC4115 GumN family protein YP_002269133.1 576662 R 444450 CDS YP_002269134.1 209400650 6969821 577540..577935 1 NC_011353.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; HigA family addiction module antidote protein 577935 6969821 ECH74115_0576 Escherichia coli O157:H7 str. EC4115 HigA family addiction module antidote protein YP_002269134.1 577540 D 444450 CDS YP_002269135.1 209399850 6971866 complement(578150..580654) 1 NC_011353.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper exporting ATPase 580654 copA 6971866 copA Escherichia coli O157:H7 str. EC4115 copper exporting ATPase YP_002269135.1 578150 R 444450 CDS YP_002269136.1 209397265 6971007 580916..581848 1 NC_011353.1 catalyzes the formation of glutamate from glutamine; glutaminase 581848 glsA1 6971007 glsA1 Escherichia coli O157:H7 str. EC4115 glutaminase YP_002269136.1 580916 D 444450 CDS YP_002269137.1 209397350 6968223 581851..583143 1 NC_011353.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845; amino acid permease family protein 583143 6968223 ECH74115_0579 Escherichia coli O157:H7 str. EC4115 amino acid permease family protein YP_002269137.1 581851 D 444450 CDS YP_002269138.1 209398272 6968317 583481..584836 1 NC_011353.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844; outer membrane transport protein 584836 6968317 ECH74115_0580 Escherichia coli O157:H7 str. EC4115 outer membrane transport protein YP_002269138.1 583481 D 444450 CDS YP_002269139.1 209395885 6969304 584939..589324 1 NC_011353.1 PKD domain-containing protein 589324 6969304 ECH74115_0581 Escherichia coli O157:H7 str. EC4115 PKD domain-containing protein YP_002269139.1 584939 D 444450 CDS YP_002269140.1 209400615 6971144 605092..607254 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR03375; type I secretion system ATPase family protein 607254 6971144 ECH74115_0584 Escherichia coli O157:H7 str. EC4115 type I secretion system ATPase family protein YP_002269140.1 605092 D 444450 CDS YP_002269141.1 209399564 6971827 607251..608426 1 NC_011353.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843; membrane spanning export protein 608426 6971827 ECH74115_0585 Escherichia coli O157:H7 str. EC4115 membrane spanning export protein YP_002269141.1 607251 D 444450 CDS YP_002269142.1 209399114 6970702 608423..608830 1 NC_011353.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 608830 cueR 6970702 cueR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator CueR YP_002269142.1 608423 D 444450 CDS YP_002269143.1 209397972 6970216 complement(608834..609001) 1 NC_011353.1 identified by glimmer; hypothetical protein 609001 6970216 ECH74115_0587 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269143.1 608834 R 444450 CDS YP_002269144.1 209400226 6968980 complement(609034..609456) 1 NC_011353.1 lipoprotein 609456 6968980 ECH74115_0588 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269144.1 609034 R 444450 CDS YP_002269145.1 209398275 6971416 complement(609541..610557) 1 NC_011353.1 identified by match to protein family HMM PF03895; hypothetical protein 610557 6971416 ECH74115_0589 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269145.1 609541 R 444450 CDS YP_002269146.1 209398992 6969307 complement(610655..610777) 1 NC_011353.1 identified by glimmer; hypothetical protein 610777 6969307 ECH74115_0590 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269146.1 610655 R 444450 CDS YP_002269147.1 209397240 6970091 610924..611286 1 NC_011353.1 hypothetical protein 611286 6970091 ECH74115_0591 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269147.1 610924 D 444450 CDS YP_002269148.1 209397476 6968198 complement(611465..611923) 1 NC_011353.1 identified by match to protein family HMM PF01957; nodulation efficiency family protein 611923 6968198 ECH74115_0592 Escherichia coli O157:H7 str. EC4115 nodulation efficiency family protein YP_002269148.1 611465 R 444450 CDS YP_002269149.1 209395731 6968447 complement(611920..612837) 1 NC_011353.1 identified by match to protein family HMM PF01145; SPFH domain/band 7 family protein 612837 6968447 ECH74115_0593 Escherichia coli O157:H7 str. EC4115 SPFH domain/band 7 family protein YP_002269149.1 611920 R 444450 CDS YP_002269150.1 209396673 6966586 612983..613660 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 613660 6966586 ECH74115_0594 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002269150.1 612983 D 444450 CDS YP_002269151.1 209400179 6967594 613647..614426 1 NC_011353.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245; hypothetical protein 614426 6967594 ECH74115_0595 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269151.1 613647 D 444450 CDS YP_002269152.1 209400420 6971366 complement(614489..615343) 1 NC_011353.1 identified by match to protein family HMM PF00085; protein YbbN 615343 ybbN 6971366 ybbN Escherichia coli O157:H7 str. EC4115 protein YbbN YP_002269152.1 614489 R 444450 CDS YP_002269153.1 209398805 6971622 complement(615404..616213) 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase 616213 6971622 ECH74115_0597 Escherichia coli O157:H7 str. EC4115 short chain dehydrogenase YP_002269153.1 615404 R 444450 CDS YP_002269154.1 209396189 6969885 complement(616203..616826) 1 NC_011353.1 identified by match to protein family HMM PF00657; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 616826 tesA 6969885 tesA Escherichia coli O157:H7 str. EC4115 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_002269154.1 616203 R 444450 CDS YP_002269155.1 209399050 6967076 616797..617483 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 617483 6967076 ECH74115_0599 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002269155.1 616797 D 444450 CDS YP_002269156.1 209398271 6970152 617480..619894 1 NC_011353.1 identified by match to protein family HMM PF02687; efflux ABC transporter permease 619894 6970152 ECH74115_0600 Escherichia coli O157:H7 str. EC4115 efflux ABC transporter permease YP_002269156.1 617480 D 444450 CDS YP_002269157.1 209400573 6969303 620324..624520 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 624520 6969303 ECH74115_0601 Escherichia coli O157:H7 str. EC4115 RHS Repeat family protein YP_002269157.1 620324 D 444450 CDS YP_002269158.1 209400577 6971214 complement(625992..627086) 1 NC_011353.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 627086 selU 6971214 selU Escherichia coli O157:H7 str. EC4115 tRNA 2-selenouridine synthase YP_002269158.1 625992 R 444450 CDS YP_002269159.1 209396184 6971788 complement(627155..628081) 1 NC_011353.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 628081 6971788 ECH74115_0605 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator AllS YP_002269159.1 627155 R 444450 CDS YP_002269160.1 209396687 6967070 628311..628793 1 NC_011353.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 628793 allA 6967070 allA Escherichia coli O157:H7 str. EC4115 ureidoglycolate hydrolase YP_002269160.1 628311 D 444450 CDS YP_002269161.1 209400082 6967609 628916..629686 1 NC_011353.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 629686 allR 6967609 allR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor AllR YP_002269161.1 628916 D 444450 CDS YP_002269162.1 209400464 6971261 629776..631557 1 NC_011353.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 631557 gcl 6971261 gcl Escherichia coli O157:H7 str. EC4115 glyoxylate carboligase YP_002269162.1 629776 D 444450 CDS YP_002269163.1 209397047 6971669 631570..632346 1 NC_011353.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234; hydroxypyruvate isomerase 632346 hyi 6971669 hyi Escherichia coli O157:H7 str. EC4115 hydroxypyruvate isomerase YP_002269163.1 631570 D 444450 CDS YP_002269164.1 209396655 6967993 632447..633325 1 NC_011353.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505; 2-hydroxy-3-oxopropionate reductase 633325 6967993 ECH74115_0610 Escherichia coli O157:H7 str. EC4115 2-hydroxy-3-oxopropionate reductase YP_002269164.1 632447 D 444450 CDS YP_002269165.1 209399459 6967576 633494..634885 1 NC_011353.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; allantoin permease 634885 6967576 ECH74115_0611 Escherichia coli O157:H7 str. EC4115 allantoin permease YP_002269165.1 633494 D 444450 CDS YP_002269166.1 209400199 6971958 636340..637641 1 NC_011353.1 identified by match to protein family HMM PF00860; purine permease YbbY 637641 6971958 ECH74115_0614 Escherichia coli O157:H7 str. EC4115 purine permease YbbY YP_002269166.1 636340 D 444450 CDS YP_002269167.1 209396440 6971387 637663..638808 1 NC_011353.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 638808 6971387 ECH74115_0615 Escherichia coli O157:H7 str. EC4115 glycerate kinase YP_002269167.1 637663 D 444450 CDS YP_002269168.1 209395822 6967350 complement(639036..639821) 1 NC_011353.1 identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214; hypothetical protein 639821 6967350 ECH74115_0616 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269168.1 639036 R 444450 CDS YP_002269169.1 209397962 6966679 complement(639832..641067) 1 NC_011353.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 641067 allC 6966679 allC Escherichia coli O157:H7 str. EC4115 allantoate amidohydrolase YP_002269169.1 639832 R 444450 CDS YP_002269170.1 209398912 6968967 complement(641089..642138) 1 NC_011353.1 identified by match to protein family HMM PF02615; match to protein family HMM TIGR03175; ureidoglycolate dehydrogenase 642138 allD 6968967 allD Escherichia coli O157:H7 str. EC4115 ureidoglycolate dehydrogenase YP_002269170.1 641089 R 444450 CDS YP_002269171.1 209396962 6970004 642455..644122 1 NC_011353.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 644122 6970004 ECH74115_0619 Escherichia coli O157:H7 str. EC4115 membrane protein FdrA YP_002269171.1 642455 D 444450 CDS YP_002269172.1 209400053 6967901 644132..645391 1 NC_011353.1 identified by match to protein family HMM PF06545; hypothetical protein 645391 6967901 ECH74115_0620 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269172.1 644132 D 444450 CDS YP_002269173.1 209398161 6971232 645402..646217 1 NC_011353.1 hypothetical protein 646217 6971232 ECH74115_0621 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269173.1 645402 D 444450 CDS YP_002269174.1 209395866 6969185 646214..647107 1 NC_011353.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; carbamate kinase 647107 arcC 6969185 arcC Escherichia coli O157:H7 str. EC4115 carbamate kinase YP_002269174.1 646214 D 444450 CDS YP_002269175.1 209399025 6966728 complement(647246..648313) 1 NC_011353.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 648313 purK 6966728 purK Escherichia coli O157:H7 str. EC4115 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002269175.1 647246 R 444450 CDS YP_002269176.1 209397178 6970125 complement(648310..648819) 1 NC_011353.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit 648819 purE 6970125 purE Escherichia coli O157:H7 str. EC4115 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_002269176.1 648310 R 444450 CDS YP_002269177.1 209398910 6968132 complement(648937..649659) 1 NC_011353.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 649659 lpxH 6968132 lpxH Escherichia coli O157:H7 str. EC4115 UDP-2,3-diacylglucosamine hydrolase YP_002269177.1 648937 R 444450 CDS YP_002269178.1 209399628 6970002 complement(649662..650156) 1 NC_011353.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase B 650156 ppiB 6970002 ppiB Escherichia coli O157:H7 str. EC4115 peptidyl-prolyl cis-trans isomerase B YP_002269178.1 649662 R 444450 CDS YP_002269179.1 209397071 6970773 650330..651715 1 NC_011353.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 651715 cysS 6970773 cysS Escherichia coli O157:H7 str. EC4115 cysteinyl-tRNA synthetase YP_002269179.1 650330 D 444450 CDS YP_002269180.1 209400239 6968017 complement(651751..652272) 1 NC_011353.1 identified by match to protein family HMM PF04307; hypothetical protein 652272 6968017 ECH74115_0628 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269180.1 651751 R 444450 CDS YP_002269181.1 209397297 6971429 complement(652380..652592) 1 NC_011353.1 hypothetical protein 652592 6971429 ECH74115_0629 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269181.1 652380 R 444450 CDS YP_002269182.1 209398701 6968258 complement(652594..653460) 1 NC_011353.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 653460 folD 6968258 folD Escherichia coli O157:H7 str. EC4115 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002269182.1 652594 R 444450 CDS YP_002269183.1 209396494 6969773 653940..654482 1 NC_011353.1 identified by match to protein family HMM PF00419; type-1 fimbrial protein-like protein 654482 6969773 ECH74115_0631 Escherichia coli O157:H7 str. EC4115 type-1 fimbrial protein-like protein YP_002269183.1 653940 D 444450 CDS YP_002269184.1 209397289 6967406 654702..655394 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC-like protein 655394 6967406 ECH74115_0632 Escherichia coli O157:H7 str. EC4115 chaperone protein FimC-like protein YP_002269184.1 654702 D 444450 CDS YP_002269185.1 209401002 6968250 655425..658034 1 NC_011353.1 identified by match to protein family HMM PF00577; outer membrane usher protein SfmD 658034 sfmD 6968250 sfmD Escherichia coli O157:H7 str. EC4115 outer membrane usher protein SfmD YP_002269185.1 655425 D 444450 CDS YP_002269186.1 209395712 6972244 658047..659054 1 NC_011353.1 mannose binding protein FimH-like protein 659054 6972244 ECH74115_0634 Escherichia coli O157:H7 str. EC4115 mannose binding protein FimH-like protein YP_002269186.1 658047 D 444450 CDS YP_002269187.1 209400190 6966567 659383..659580 1 NC_011353.1 fimbrial protein 659580 6966567 ECH74115_0635 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002269187.1 659383 D 444450 CDS YP_002269188.1 209400942 6971377 complement(659583..660215) 1 NC_011353.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 660215 fimZ 6971377 fimZ Escherichia coli O157:H7 str. EC4115 transcriptional regulator FimZ YP_002269188.1 659583 R 444450 CDS YP_002269189.1 209398706 6972179 660270..660425 1 NC_011353.1 identified by glimmer; hypothetical protein 660425 6972179 ECH74115_0637 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269189.1 660270 D 444450 CDS YP_002269190.1 209396048 6972390 complement(660580..661341) 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 661341 6972390 ECH74115_0639 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002269190.1 660580 R 444450 CDS YP_002269191.1 209399136 6966925 complement(661524..662414) 1 NC_011353.1 hypothetical protein 662414 6966925 ECH74115_0640 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269191.1 661524 R 444450 CDS YP_002269192.1 209397557 6970240 complement(662415..665387) 1 NC_011353.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; bacteriophage N4 receptor, outer membrane subunit 665387 6970240 ECH74115_0641 Escherichia coli O157:H7 str. EC4115 bacteriophage N4 receptor, outer membrane subunit YP_002269192.1 662415 R 444450 CDS YP_002269193.1 209400631 6968533 complement(665374..667611) 1 NC_011353.1 identified by match to protein family HMM PF05157; bacteriophage N4 adsorption protein B 667611 nfrB 6968533 nfrB Escherichia coli O157:H7 str. EC4115 bacteriophage N4 adsorption protein B YP_002269193.1 665374 R 444450 CDS YP_002269194.1 209398400 6971845 complement(667877..669013) 1 NC_011353.1 identified by match to protein family HMM PF01609; ISEc4, transposase 669013 6971845 ECH74115_0643 Escherichia coli O157:H7 str. EC4115 ISEc4, transposase YP_002269194.1 667877 R 444450 CDS YP_002269195.1 209400670 6969446 complement(669228..669437) 1 NC_011353.1 hypothetical protein 669437 6969446 ECH74115_0644 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269195.1 669228 R 444450 CDS YP_002269196.1 209398385 6971888 complement(669476..670810) 1 NC_011353.1 identified by match to protein family HMM PF05593; match to protein family HMM TIGR01643; Rhs core protein 670810 6971888 ECH74115_0645 Escherichia coli O157:H7 str. EC4115 Rhs core protein YP_002269196.1 669476 R 444450 CDS YP_002269197.1 209396800 6967509 complement(671403..676253) 1 NC_011353.1 identified by match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 676253 6967509 ECH74115_0647 Escherichia coli O157:H7 str. EC4115 RHS Repeat family protein YP_002269197.1 671403 R 444450 CDS YP_002269198.1 209397403 6967732 complement(676273..676734) 1 NC_011353.1 identified by match to protein family HMM PF08786; hypothetical protein 676734 6967732 ECH74115_0648 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269198.1 676273 R 444450 CDS YP_002269199.1 209397950 6968369 complement(676762..678663) 1 NC_011353.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 678663 6968369 ECH74115_0649 Escherichia coli O157:H7 str. EC4115 ImpA family type VI secretion-associated protein YP_002269199.1 676762 R 444450 CDS YP_002269200.1 209398281 6968954 complement(679257..680705) 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; sensor kinase CusS 680705 cusS 6968954 cusS Escherichia coli O157:H7 str. EC4115 sensor kinase CusS YP_002269200.1 679257 R 444450 CDS YP_002269201.1 209398379 6969314 complement(680695..681378) 1 NC_011353.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 681378 cusR 6969314 cusR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator CusR YP_002269201.1 680695 R 444450 CDS YP_002269202.1 209399226 6969422 681425..681580 1 NC_011353.1 identified by glimmer; hypothetical protein 681580 6969422 ECH74115_0652 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269202.1 681425 D 444450 CDS YP_002269203.1 209399978 6970337 681535..682917 1 NC_011353.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 682917 cusC 6970337 cusC Escherichia coli O157:H7 str. EC4115 copper/silver efflux system outer membrane protein CusC YP_002269203.1 681535 D 444450 CDS YP_002269204.1 209396059 6971150 682941..683273 1 NC_011353.1 copper-binding protein 683273 cusF 6971150 cusF Escherichia coli O157:H7 str. EC4115 copper-binding protein YP_002269204.1 682941 D 444450 CDS YP_002269205.1 209400334 6966936 683289..684512 1 NC_011353.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 684512 cusB 6966936 cusB Escherichia coli O157:H7 str. EC4115 copper/silver efflux system membrane fusion protein CusB YP_002269205.1 683289 D 444450 CDS YP_002269206.1 209396317 6971531 684524..687661 1 NC_011353.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; cation efflux system protein cusA 687661 cusA 6971531 cusA Escherichia coli O157:H7 str. EC4115 cation efflux system protein cusA YP_002269206.1 684524 D 444450 CDS YP_002269207.1 209396862 6967213 687727..689139 1 NC_011353.1 identified by match to protein family HMM PF00324; phenylalanine transporter 689139 pheP 6967213 pheP Escherichia coli O157:H7 str. EC4115 phenylalanine transporter YP_002269207.1 687727 D 444450 CDS YP_002269208.1 209398966 6967797 complement(689207..690454) 1 NC_011353.1 identified by match to protein family HMM PF00924; transporter small conductance mechanosensitive ion channel (MscS) family 690454 6967797 ECH74115_0658 Escherichia coli O157:H7 str. EC4115 transporter small conductance mechanosensitive ion channel (MscS) family YP_002269208.1 689207 R 444450 CDS YP_002269209.1 209400820 6970061 complement(690562..691215) 1 NC_011353.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 691215 nfnB 6970061 nfnB Escherichia coli O157:H7 str. EC4115 dihydropteridine reductase YP_002269209.1 690562 R 444450 CDS YP_002269210.1 209398435 6972048 complement(691309..691677) 1 NC_011353.1 identified by match to protein family HMM PF04237; hypothetical protein 691677 6972048 ECH74115_0660 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269210.1 691309 R 444450 CDS YP_002269211.1 209398908 6969487 complement(691742..691990) 1 NC_011353.1 identified by match to protein family HMM PF06643; lipoprotein 691990 6969487 ECH74115_0661 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269211.1 691742 R 444450 CDS YP_002269212.1 209400990 6970000 complement(692056..693174) 1 NC_011353.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 693174 6970000 ECH74115_0662 Escherichia coli O157:H7 str. EC4115 carboxylate-amine ligase YP_002269212.1 692056 R 444450 CDS YP_002269213.1 209396640 6971231 693799..693933 1 NC_011353.1 identified by glimmer; hypothetical protein 693933 6971231 ECH74115_0664 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269213.1 693799 D 444450 CDS YP_002269214.1 209395884 6967560 694116..694268 1 NC_011353.1 identified by match to protein family HMM PF01848; Hok/Gef family protein 694268 6967560 ECH74115_0665 Escherichia coli O157:H7 str. EC4115 Hok/Gef family protein YP_002269214.1 694116 D 444450 CDS YP_002269215.1 209397802 6966748 complement(694390..695019) 1 NC_011353.1 identified by match to protein family HMM PF01648; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 695019 entD 6966748 entD Escherichia coli O157:H7 str. EC4115 enterobactin synthase multienzyme complex phosphopantetheinyltransferase YP_002269215.1 694390 R 444450 CDS YP_002269216.1 209397038 6968791 complement(695185..697425) 1 NC_011353.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 697425 fepA 6968791 fepA Escherichia coli O157:H7 str. EC4115 outer membrane receptor FepA YP_002269216.1 695185 R 444450 CDS YP_002269217.1 209398840 6967982 697418..697549 1 NC_011353.1 identified by glimmer; hypothetical protein 697549 6967982 ECH74115_0668 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269217.1 697418 D 444450 CDS YP_002269218.1 209395931 6969924 697668..698870 1 NC_011353.1 identified by match to protein family HMM PF00756; enterobactin/ferric enterobactin esterase 698870 fes 6969924 fes Escherichia coli O157:H7 str. EC4115 enterobactin/ferric enterobactin esterase YP_002269218.1 697668 D 444450 CDS YP_002269219.1 209400967 6966798 698873..699091 1 NC_011353.1 identified by match to protein family HMM PF03621; mbtH-like protein 699091 6966798 ECH74115_0670 Escherichia coli O157:H7 str. EC4115 mbtH-like protein YP_002269219.1 698873 D 444450 CDS YP_002269220.1 209400326 6972207 699088..702969 1 NC_011353.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 702969 entF 6972207 entF Escherichia coli O157:H7 str. EC4115 enterobactin synthase subunit F YP_002269220.1 699088 D 444450 CDS YP_002269221.1 209398787 6971522 703185..704318 1 NC_011353.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 704318 fepE 6971522 fepE Escherichia coli O157:H7 str. EC4115 ferric enterobactin transport protein FepE YP_002269221.1 703185 D 444450 CDS YP_002269222.1 209399490 6969865 complement(704315..705130) 1 NC_011353.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 705130 fepC 6969865 fepC Escherichia coli O157:H7 str. EC4115 iron-enterobactin transporter ATP-binding protein YP_002269222.1 704315 R 444450 CDS YP_002269223.1 209400073 6970624 complement(705127..706119) 1 NC_011353.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 706119 fepG 6970624 fepG Escherichia coli O157:H7 str. EC4115 iron-enterobactin transporter permease YP_002269223.1 705127 R 444450 CDS YP_002269224.1 209399652 6971252 complement(706116..707120) 1 NC_011353.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 707120 fepD 6971252 fepD Escherichia coli O157:H7 str. EC4115 iron-enterobactin transporter membrane protein YP_002269224.1 706116 R 444450 CDS YP_002269225.1 209398565 6970798 707231..708481 1 NC_011353.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 708481 6970798 ECH74115_0676 Escherichia coli O157:H7 str. EC4115 enterobactin exporter EntS YP_002269225.1 707231 D 444450 CDS YP_002269226.1 209398102 6969626 complement(708485..709441) 1 NC_011353.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 709441 fepB 6969626 fepB Escherichia coli O157:H7 str. EC4115 iron-enterobactin transporter periplasmic binding protein YP_002269226.1 708485 R 444450 CDS YP_002269227.1 209397985 6969120 709630..710805 1 NC_011353.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase, entC 710805 entC 6969120 entC Escherichia coli O157:H7 str. EC4115 isochorismate synthase, entC YP_002269227.1 709630 D 444450 CDS YP_002269228.1 209396204 6968996 710815..712425 1 NC_011353.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 712425 entE 6968996 entE Escherichia coli O157:H7 str. EC4115 enterobactin synthase subunit E YP_002269228.1 710815 D 444450 CDS YP_002269229.1 209396636 6967091 712439..713296 1 NC_011353.1 identified by match to protein family HMM PF00550; match to protein family HMM PF00857; isochorismatase 713296 entB 6967091 entB Escherichia coli O157:H7 str. EC4115 isochorismatase YP_002269229.1 712439 D 444450 CDS YP_002269230.1 209397468 6967556 713296..714042 1 NC_011353.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 714042 entA 6967556 entA Escherichia coli O157:H7 str. EC4115 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_002269230.1 713296 D 444450 CDS YP_002269231.1 209397763 6968439 714045..714458 1 NC_011353.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 714458 6968439 ECH74115_0682 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269231.1 714045 D 444450 CDS YP_002269232.1 209398506 6968750 714639..716744 1 NC_011353.1 identified by match to protein family HMM PF02554; carbon starvation protein A 716744 cstA 6968750 cstA Escherichia coli O157:H7 str. EC4115 carbon starvation protein A YP_002269232.1 714639 D 444450 CDS YP_002269233.1 209398096 6969564 716926..717123 1 NC_011353.1 identified by match to protein family HMM PF04328; hypothetical protein 717123 6969564 ECH74115_0684 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269233.1 716926 D 444450 CDS YP_002269234.1 209399003 6969114 complement(717133..718221) 1 NC_011353.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 718221 6969114 ECH74115_0685 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269234.1 717133 R 444450 CDS YP_002269235.1 209399170 6970102 718330..719490 1 NC_011353.1 catalyzes the transfer of an amino moiety; aminotransferase 719490 6970102 ECH74115_0686 Escherichia coli O157:H7 str. EC4115 aminotransferase YP_002269235.1 718330 D 444450 CDS YP_002269236.1 209400086 6970278 complement(719491..720120) 1 NC_011353.1 identified by match to protein family HMM PF02195; IbrB protein 720120 6970278 ECH74115_0687 Escherichia coli O157:H7 str. EC4115 IbrB protein YP_002269236.1 719491 R 444450 CDS YP_002269237.1 209400360 6971266 complement(720093..721313) 1 NC_011353.1 identified by match to protein family HMM PF01507; IbrA protein 721313 6971266 ECH74115_0688 Escherichia coli O157:H7 str. EC4115 IbrA protein YP_002269237.1 720093 R 444450 CDS YP_002269238.1 209397013 6971558 complement(721460..722362) 1 NC_011353.1 identified by match to protein family HMM PF00126; LysR family transcriptional regulator 722362 6971558 ECH74115_0689 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002269238.1 721460 R 444450 CDS YP_002269239.1 209399269 6967956 complement(722572..723318) 1 NC_011353.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 723318 dsbG 6967956 dsbG Escherichia coli O157:H7 str. EC4115 disulfide isomerase/thiol-disulfide oxidase YP_002269239.1 722572 R 444450 CDS YP_002269240.1 209398641 6970385 723690..724253 1 NC_011353.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 724253 ahpC 6970385 ahpC Escherichia coli O157:H7 str. EC4115 alkyl hydroperoxide reductase subunit C YP_002269240.1 723690 D 444450 CDS YP_002269241.1 209400565 6969708 724352..725947 1 NC_011353.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140; alkyl hydroperoxide reductase subunit F 725947 ahpF 6969708 ahpF Escherichia coli O157:H7 str. EC4115 alkyl hydroperoxide reductase subunit F YP_002269241.1 724352 D 444450 CDS YP_002269242.1 209399786 6971774 complement(726068..726496) 1 NC_011353.1 identified by match to protein family HMM PF00582; universal stress protein G 726496 uspG 6971774 uspG Escherichia coli O157:H7 str. EC4115 universal stress protein G YP_002269242.1 726068 R 444450 CDS YP_002269243.1 209396266 6970855 726717..727955 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 727955 6970855 ECH74115_0695 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002269243.1 726717 D 444450 CDS YP_002269244.1 209398188 6967159 complement(727959..728147) 1 NC_011353.1 identified by glimmer; hypothetical protein 728147 6967159 ECH74115_0696 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269244.1 727959 R 444450 CDS YP_002269245.1 209397427 6969216 complement(728186..728596) 1 NC_011353.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 728596 rnk 6969216 rnk Escherichia coli O157:H7 str. EC4115 nucleoside diphosphate kinase regulator YP_002269245.1 728186 R 444450 CDS YP_002269246.1 209397451 6968396 complement(728571..728732) 1 NC_011353.1 identified by glimmer; hypothetical protein 728732 6968396 ECH74115_0698 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269246.1 728571 R 444450 CDS YP_002269247.1 209397324 6968422 complement(728826..729632) 1 NC_011353.1 identified by match to protein family HMM PF00445; ribonuclease I 729632 rna 6968422 rna Escherichia coli O157:H7 str. EC4115 ribonuclease I YP_002269247.1 728826 R 444450 CDS YP_002269248.1 209400659 6968287 complement(729746..731176) 1 NC_011353.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; sodium:sulfate symporter family protein 731176 6968287 ECH74115_0700 Escherichia coli O157:H7 str. EC4115 sodium:sulfate symporter family protein YP_002269248.1 729746 R 444450 CDS YP_002269249.1 209400680 6971875 complement(731260..732132) 1 NC_011353.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 732132 citG 6971875 citG Escherichia coli O157:H7 str. EC4115 triphosphoribosyl-dephospho-CoA synthase YP_002269249.1 731260 R 444450 CDS YP_002269250.1 209400121 6971900 complement(732113..732664) 1 NC_011353.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 732664 citX 6971900 citX Escherichia coli O157:H7 str. EC4115 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_002269250.1 732113 R 444450 CDS YP_002269251.1 209396876 6971306 complement(732668..734200) 1 NC_011353.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584; citrate lyase subunit alpha 734200 citF 6971306 citF Escherichia coli O157:H7 str. EC4115 citrate lyase subunit alpha YP_002269251.1 732668 R 444450 CDS YP_002269252.1 209398234 6967813 complement(734211..735119) 1 NC_011353.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588; citrate (pro-3S)-lyase subunit beta 735119 citE 6967813 citE Escherichia coli O157:H7 str. EC4115 citrate (pro-3S)-lyase subunit beta YP_002269252.1 734211 R 444450 CDS YP_002269253.1 209397645 6969265 complement(735116..735412) 1 NC_011353.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 735412 citD 6969265 citD Escherichia coli O157:H7 str. EC4115 citrate lyase subunit gamma YP_002269253.1 735116 R 444450 CDS YP_002269254.1 209399120 6968628 complement(735427..736485) 1 NC_011353.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125; citrate lyase synthetase 736485 citC 6968628 citC Escherichia coli O157:H7 str. EC4115 citrate lyase synthetase YP_002269254.1 735427 R 444450 CDS YP_002269255.1 209398542 6970222 736865..738523 1 NC_011353.1 identified by match to protein family HMM PF02518; sensor histidine kinase DpiB 738523 dpiB 6970222 dpiB Escherichia coli O157:H7 str. EC4115 sensor histidine kinase DpiB YP_002269255.1 736865 D 444450 CDS YP_002269256.1 209398581 6969601 738492..739172 1 NC_011353.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 739172 dpiA 6969601 dpiA Escherichia coli O157:H7 str. EC4115 two-component response regulator DpiA YP_002269256.1 738492 D 444450 CDS YP_002269257.1 209396097 6969642 complement(739213..740598) 1 NC_011353.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 740598 dcuC 6969642 dcuC Escherichia coli O157:H7 str. EC4115 C4-dicarboxylate transporter DcuC YP_002269257.1 739213 R 444450 CDS YP_002269258.1 209400211 6971566 741187..741747 1 NC_011353.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 741747 pagP 6971566 pagP Escherichia coli O157:H7 str. EC4115 palmitoyl transferase YP_002269258.1 741187 D 444450 CDS YP_002269259.1 209399192 6971399 741922..742131 1 NC_011353.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 742131 cspE 6971399 cspE Escherichia coli O157:H7 str. EC4115 cold shock protein CspE YP_002269259.1 741922 D 444450 CDS YP_002269260.1 209398394 6970300 complement(742185..742568) 1 NC_011353.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 742568 crcB 6970300 crcB Escherichia coli O157:H7 str. EC4115 camphor resistance protein CrcB YP_002269260.1 742185 R 444450 CDS YP_002269261.1 209400594 6969438 742661..743449 1 NC_011353.1 identified by match to protein family HMM PF00795; hydrolase 743449 6969438 ECH74115_0714 Escherichia coli O157:H7 str. EC4115 hydrolase YP_002269261.1 742661 D 444450 CDS YP_002269262.1 209399866 6971805 743578..743781 1 NC_011353.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 743781 tatE 6971805 tatE Escherichia coli O157:H7 str. EC4115 twin arginine translocase E YP_002269262.1 743578 D 444450 CDS YP_002269263.1 209399163 6971025 complement(743882..744847) 1 NC_011353.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 744847 lipA 6971025 lipA Escherichia coli O157:H7 str. EC4115 lipoyl synthase YP_002269263.1 743882 R 444450 CDS YP_002269264.1 209398455 6970271 complement(745056..746009) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 746009 6970271 ECH74115_0717 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002269264.1 745056 R 444450 CDS YP_002269265.1 209398729 6969508 complement(746269..746910) 1 NC_011353.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 746910 lipB 6969508 lipB Escherichia coli O157:H7 str. EC4115 lipoate-protein ligase B YP_002269265.1 746269 R 444450 CDS YP_002269266.1 209398349 6969803 complement(747011..747274) 1 NC_011353.1 identified by match to protein family HMM PF04359; hypothetical protein 747274 6969803 ECH74115_0719 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269266.1 747011 R 444450 CDS YP_002269267.1 209398518 6969389 complement(747384..748595) 1 NC_011353.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 748595 dacA 6969389 dacA Escherichia coli O157:H7 str. EC4115 D-alanyl-D-alanine carboxypeptidase YP_002269267.1 747384 R 444450 CDS YP_002269268.1 209398342 6969577 748618..748758 1 NC_011353.1 hypothetical protein 748758 6969577 ECH74115_0722 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269268.1 748618 D 444450 CDS YP_002269269.1 209399263 6969382 complement(748735..749823) 1 NC_011353.1 identified by match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413; rare lipoprotein A 749823 rlpA 6969382 rlpA Escherichia coli O157:H7 str. EC4115 rare lipoprotein A YP_002269269.1 748735 R 444450 CDS YP_002269270.1 209396066 6970379 complement(749834..750946) 1 NC_011353.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; cell wall shape-determining protein 750946 mrdB 6970379 mrdB Escherichia coli O157:H7 str. EC4115 cell wall shape-determining protein YP_002269270.1 749834 R 444450 CDS YP_002269271.1 209400528 6966945 complement(750949..752850) 1 NC_011353.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423; penicillin-binding protein 2 752850 mrdA 6966945 mrdA Escherichia coli O157:H7 str. EC4115 penicillin-binding protein 2 YP_002269271.1 750949 R 444450 CDS YP_002269272.1 209398659 6971735 complement(752881..753348) 1 NC_011353.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 753348 6971735 ECH74115_0725 Escherichia coli O157:H7 str. EC4115 rRNA large subunit methyltransferase YP_002269272.1 752881 R 444450 CDS YP_002269273.1 209397396 6969729 complement(753352..753669) 1 NC_011353.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein 753669 6969729 ECH74115_0726 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269273.1 753352 R 444450 CDS YP_002269274.1 209397212 6968362 complement(753929..754540) 1 NC_011353.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR03162; alpha-ribazole phosphatase 754540 cobC 6968362 cobC Escherichia coli O157:H7 str. EC4115 alpha-ribazole phosphatase YP_002269274.1 753929 R 444450 CDS YP_002269275.1 209398341 6968170 complement(754564..755205) 1 NC_011353.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 755205 nadD 6968170 nadD Escherichia coli O157:H7 str. EC4115 nicotinic acid mononucleotide adenylyltransferase YP_002269275.1 754564 R 444450 CDS YP_002269276.1 209397273 6969381 complement(755207..756238) 1 NC_011353.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 756238 holA 6969381 holA Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit delta YP_002269276.1 755207 R 444450 CDS YP_002269277.1 209396902 6968233 complement(756238..756819) 1 NC_011353.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 756819 6968233 ECH74115_0730 Escherichia coli O157:H7 str. EC4115 LPS-assembly lipoprotein RlpB YP_002269277.1 756238 R 444450 CDS YP_002269278.1 209396207 6967840 complement(756834..759416) 1 NC_011353.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 759416 leuS 6967840 leuS Escherichia coli O157:H7 str. EC4115 leucyl-tRNA synthetase YP_002269278.1 756834 R 444450 CDS YP_002269279.1 209398105 6967095 759652..760134 1 NC_011353.1 identified by match to protein family HMM PF07295; hypothetical protein 760134 6967095 ECH74115_0732 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269279.1 759652 D 444450 CDS YP_002269280.1 209399496 6971304 761346..762053 1 NC_011353.1 identified by match to protein family HMM PF06889; hypothetical protein 762053 6971304 ECH74115_0735 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269280.1 761346 D 444450 CDS YP_002269281.1 209396284 6970630 762050..763477 1 NC_011353.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 763477 6970630 ECH74115_0736 Escherichia coli O157:H7 str. EC4115 DnaJ domain-containing protein YP_002269281.1 762050 D 444450 CDS YP_002269282.1 209400357 6967178 complement(763487..764041) 1 NC_011353.1 identified by match to protein family HMM PF08238; hypothetical protein 764041 6967178 ECH74115_0737 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269282.1 763487 R 444450 CDS YP_002269283.1 209397119 6971555 764143..764850 1 NC_011353.1 identified by match to protein family HMM PF06889; hypothetical protein 764850 6971555 ECH74115_0738 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269283.1 764143 D 444450 CDS YP_002269284.1 209400920 6970523 766264..766401 1 NC_011353.1 identified by glimmer; hypothetical protein 766401 6970523 ECH74115_0742 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269284.1 766264 D 444450 CDS YP_002269285.1 209398988 6972157 complement(766358..768028) 1 NC_011353.1 identified by match to protein family HMM PF00012; DnaK family protein HscC 768028 hscC 6972157 hscC Escherichia coli O157:H7 str. EC4115 DnaK family protein HscC YP_002269285.1 766358 R 444450 CDS YP_002269286.1 209396421 6970087 complement(768112..769047) 1 NC_011353.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 769047 rihA 6970087 rihA Escherichia coli O157:H7 str. EC4115 ribonucleoside hydrolase 1 YP_002269286.1 768112 R 444450 CDS YP_002269287.1 209395778 6967328 complement(769165..769890) 1 NC_011353.1 identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter ATP-binding protein 769890 gltL 6967328 gltL Escherichia coli O157:H7 str. EC4115 glutamate/aspartate ABC transporter ATP-binding protein YP_002269287.1 769165 R 444450 CDS YP_002269288.1 209397952 6966634 complement(769890..770564) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltK 770564 gltK 6966634 gltK Escherichia coli O157:H7 str. EC4115 glutamate/aspartate ABC transporter permease GltK YP_002269288.1 769890 R 444450 CDS YP_002269289.1 209397185 6968956 complement(770564..771304) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltJ 771304 gltJ 6968956 gltJ Escherichia coli O157:H7 str. EC4115 glutamate/aspartate ABC transporter permease GltJ YP_002269289.1 770564 R 444450 CDS YP_002269290.1 209399444 6972300 complement(771474..772382) 1 NC_011353.1 identified by match to protein family HMM PF00497; glutamate and aspartate transporter subunit 772382 gltI 6972300 gltI Escherichia coli O157:H7 str. EC4115 glutamate and aspartate transporter subunit YP_002269290.1 771474 R 444450 CDS YP_002269291.1 209398523 6970572 772672..772794 1 NC_011353.1 identified by glimmer; hypothetical protein 772794 6970572 ECH74115_0750 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269291.1 772672 D 444450 CDS YP_002269292.1 209398690 6969582 complement(772779..774317) 1 NC_011353.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 774317 lnt 6969582 lnt Escherichia coli O157:H7 str. EC4115 apolipoprotein N-acyltransferase YP_002269292.1 772779 R 444450 CDS YP_002269293.1 209398266 6969761 complement(774342..775220) 1 NC_011353.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; magnesium and cobalt efflux protein CorC 775220 corC 6969761 corC Escherichia coli O157:H7 str. EC4115 magnesium and cobalt efflux protein CorC YP_002269293.1 774342 R 444450 CDS YP_002269294.1 209397406 6969298 complement(775310..775777) 1 NC_011353.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; metalloprotease 775777 6969298 ECH74115_0752 Escherichia coli O157:H7 str. EC4115 metalloprotease YP_002269294.1 775310 R 444450 CDS YP_002269295.1 209396833 6968372 complement(775774..776814) 1 NC_011353.1 identified by match to protein family HMM PF02562; PhoH family protein 776814 6968372 ECH74115_0753 Escherichia coli O157:H7 str. EC4115 PhoH family protein YP_002269295.1 775774 R 444450 CDS YP_002269296.1 209396467 6967766 complement(776873..776992) 1 NC_011353.1 identified by glimmer; hypothetical protein 776992 6967766 ECH74115_0754 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269296.1 776873 R 444450 CDS YP_002269297.1 209395752 6967378 complement(776967..778391) 1 NC_011353.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 778391 miaB 6967378 miaB Escherichia coli O157:H7 str. EC4115 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002269297.1 776967 R 444450 CDS YP_002269298.1 209400601 6966607 778537..779712 1 NC_011353.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 779712 ubiF 6966607 ubiF Escherichia coli O157:H7 str. EC4115 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002269298.1 778537 D 444450 CDS YP_002269299.1 209399871 6972371 complement(780951..782615) 1 NC_011353.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 782615 asnB 6972371 asnB Escherichia coli O157:H7 str. EC4115 asparagine synthetase B YP_002269299.1 780951 R 444450 CDS YP_002269300.1 209399473 6971030 782584..782748 1 NC_011353.1 lipoprotein 782748 6971030 ECH74115_0765 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269300.1 782584 D 444450 CDS YP_002269301.1 209398777 6970605 complement(782872..783624) 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460; UMP phosphatase 783624 nagD 6970605 nagD Escherichia coli O157:H7 str. EC4115 UMP phosphatase YP_002269301.1 782872 R 444450 CDS YP_002269302.1 209400377 6969855 complement(783672..784892) 1 NC_011353.1 identified by match to protein family HMM PF00480; N-acetylglucosamine repressor 784892 nagC 6969855 nagC Escherichia coli O157:H7 str. EC4115 N-acetylglucosamine repressor YP_002269302.1 783672 R 444450 CDS YP_002269303.1 209396073 6971577 complement(784901..786049) 1 NC_011353.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 786049 nagA 6971577 nagA Escherichia coli O157:H7 str. EC4115 N-acetylglucosamine-6-phosphate deacetylase YP_002269303.1 784901 R 444450 CDS YP_002269304.1 209396794 6966952 complement(786109..786909) 1 NC_011353.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 786909 nagB 6966952 nagB Escherichia coli O157:H7 str. EC4115 glucosamine-6-phosphate deaminase YP_002269304.1 786109 R 444450 CDS YP_002269305.1 209397146 6967725 complement(786958..787083) 1 NC_011353.1 identified by glimmer; hypothetical protein 787083 6967725 ECH74115_0770 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269305.1 786958 R 444450 CDS YP_002269306.1 209398022 6968098 787242..789188 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 789188 nagE 6968098 nagE Escherichia coli O157:H7 str. EC4115 PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_002269306.1 787242 D 444450 CDS YP_002269307.1 209397744 6969035 complement(789158..789313) 1 NC_011353.1 identified by glimmer; hypothetical protein 789313 6969035 ECH74115_0771 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269307.1 789158 R 444450 CDS YP_002269308.1 209398924 6968729 789391..791055 1 NC_011353.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 791055 glnS 6968729 glnS Escherichia coli O157:H7 str. EC4115 glutaminyl-tRNA synthetase YP_002269308.1 789391 D 444450 CDS YP_002269309.1 209399206 6970017 complement(791128..791322) 1 NC_011353.1 enterobactin synthase multienzyme complex phosphopantetheinyltransferase 791322 6970017 ECH74115_0774 Escherichia coli O157:H7 str. EC4115 enterobactin synthase multienzyme complex phosphopantetheinyltransferase YP_002269309.1 791128 R 444450 CDS YP_002269310.1 209397862 6971584 793089..793415 1 NC_011353.1 lipoprotein 793415 6971584 ECH74115_0777 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269310.1 793089 D 444450 CDS YP_002269311.1 209399187 6968854 complement(793499..793945) 1 NC_011353.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 793945 fur 6968854 fur Escherichia coli O157:H7 str. EC4115 ferric uptake regulator YP_002269311.1 793499 R 444450 CDS YP_002269312.1 209400113 6970295 complement(794234..794764) 1 NC_011353.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 794764 fldA 6970295 fldA Escherichia coli O157:H7 str. EC4115 flavodoxin FldA YP_002269312.1 794234 R 444450 CDS YP_002269313.1 209400738 6971296 complement(794904..795266) 1 NC_011353.1 identified by match to protein family HMM PF01402; LexA regulated protein 795266 6971296 ECH74115_0780 Escherichia coli O157:H7 str. EC4115 LexA regulated protein YP_002269313.1 794904 R 444450 CDS YP_002269314.1 209396278 6971963 complement(795337..796101) 1 NC_011353.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819; hypothetical protein 796101 ybfF 6971963 ybfF Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269314.1 795337 R 444450 CDS YP_002269315.1 209396469 6967172 796286..796831 1 NC_011353.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 796831 seqA 6967172 seqA Escherichia coli O157:H7 str. EC4115 replication initiation regulator SeqA YP_002269315.1 796286 D 444450 CDS YP_002269316.1 209398192 6967380 796857..798497 1 NC_011353.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 798497 pgm 6967380 pgm Escherichia coli O157:H7 str. EC4115 phosphoglucomutase YP_002269316.1 796857 D 444450 CDS YP_002269317.1 209397966 6969220 complement(798554..799873) 1 NC_011353.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 799873 potE 6969220 potE Escherichia coli O157:H7 str. EC4115 putrescine transporter YP_002269317.1 798554 R 444450 CDS YP_002269318.1 209398410 6968971 complement(799870..802077) 1 NC_011353.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase 802077 speF 6968971 speF Escherichia coli O157:H7 str. EC4115 ornithine decarboxylase YP_002269318.1 799870 R 444450 CDS YP_002269319.1 209400080 6969456 complement(802462..802596) 1 NC_011353.1 identified by glimmer; hypothetical protein 802596 6969456 ECH74115_0786 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269319.1 802462 R 444450 CDS YP_002269320.1 209398256 6971259 complement(802758..803435) 1 NC_011353.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 803435 kdpE 6971259 kdpE Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator KdpE YP_002269320.1 802758 R 444450 CDS YP_002269321.1 209397561 6969288 complement(803432..806116) 1 NC_011353.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 806116 kdpD 6969288 kdpD Escherichia coli O157:H7 str. EC4115 sensor protein KdpD YP_002269321.1 803432 R 444450 CDS YP_002269322.1 209397390 6968537 complement(806109..806681) 1 NC_011353.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 806681 kdpC 6968537 kdpC Escherichia coli O157:H7 str. EC4115 potassium-transporting ATPase subunit C YP_002269322.1 806109 R 444450 CDS YP_002269323.1 209396945 6968356 complement(806690..808738) 1 NC_011353.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 808738 kdpB 6968356 kdpB Escherichia coli O157:H7 str. EC4115 potassium-transporting ATPase subunit B YP_002269323.1 806690 R 444450 CDS YP_002269324.1 209395951 6967883 complement(808761..810434) 1 NC_011353.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 810434 kdpA 6967883 kdpA Escherichia coli O157:H7 str. EC4115 potassium-transporting ATPase subunit A YP_002269324.1 808761 R 444450 CDS YP_002269325.1 209400837 6966818 810836..811042 1 NC_011353.1 hypothetical protein 811042 6966818 ECH74115_0792 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269325.1 810836 D 444450 CDS YP_002269326.1 209398958 6972068 811043..811225 1 NC_011353.1 identified by glimmer; hypothetical protein 811225 6972068 ECH74115_0793 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269326.1 811043 D 444450 CDS YP_002269327.1 209398370 6970052 811282..815481 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS repeat protein 815481 6970052 ECH74115_0794 Escherichia coli O157:H7 str. EC4115 RHS repeat protein YP_002269327.1 811282 D 444450 CDS YP_002269328.1 209397505 6969413 815478..816047 1 NC_011353.1 identified by glimmer; hypothetical protein 816047 6969413 ECH74115_0795 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269328.1 815478 D 444450 CDS YP_002269329.1 209396877 6968477 817634..818770 1 NC_011353.1 identified by match to protein family HMM PF01609; ISEc4, transposase 818770 6968477 ECH74115_0796 Escherichia coli O157:H7 str. EC4115 ISEc4, transposase YP_002269329.1 817634 D 444450 CDS YP_002269330.1 209395854 6967814 818919..819428 1 NC_011353.1 identified by match to protein family HMM PF08349; hypothetical protein 819428 6967814 ECH74115_0797 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269330.1 818919 D 444450 CDS YP_002269331.1 209397896 6966712 819425..820843 1 NC_011353.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 820843 phrB 6966712 phrB Escherichia coli O157:H7 str. EC4115 deoxyribodipyrimidine photolyase YP_002269331.1 819425 D 444450 CDS YP_002269332.1 209398739 6968894 complement(820993..822474) 1 NC_011353.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 822474 6968894 ECH74115_0799 Escherichia coli O157:H7 str. EC4115 amino acid/peptide transporter YP_002269332.1 820993 R 444450 CDS YP_002269333.1 209400852 6969815 822745..823488 1 NC_011353.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hydrolase-oxidase 823488 6969815 ECH74115_0800 Escherichia coli O157:H7 str. EC4115 hydrolase-oxidase YP_002269333.1 822745 D 444450 CDS YP_002269334.1 209400269 6972083 823511..824167 1 NC_011353.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370; allophanate hydrolase, subunit 1 824167 6972083 ECH74115_0801 Escherichia coli O157:H7 str. EC4115 allophanate hydrolase, subunit 1 YP_002269334.1 823511 D 444450 CDS YP_002269335.1 209396411 6971462 824161..825093 1 NC_011353.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724; allophanate hydrolase subunit 2 825093 6971462 ECH74115_0802 Escherichia coli O157:H7 str. EC4115 allophanate hydrolase subunit 2 YP_002269335.1 824161 D 444450 CDS YP_002269336.1 209396404 6967318 825083..825817 1 NC_011353.1 identified by match to protein family HMM PF03746; LamB/YcsF family protein 825817 6967318 ECH74115_0803 Escherichia coli O157:H7 str. EC4115 LamB/YcsF family protein YP_002269336.1 825083 D 444450 CDS YP_002269337.1 209395870 6968938 complement(826640..827686) 1 NC_011353.1 identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082; protein AbrB 827686 abrB 6968938 abrB Escherichia coli O157:H7 str. EC4115 protein AbrB YP_002269337.1 826640 R 444450 CDS YP_002269338.1 209399368 6966734 complement(827835..828896) 1 NC_011353.1 hypothetical protein 828896 6966734 ECH74115_0806 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269338.1 827835 R 444450 CDS YP_002269339.1 209398774 6970492 complement(828893..829624) 1 NC_011353.1 identified by match to protein family HMM PF00345; periplasmic pilus chaperone family protein 829624 6970492 ECH74115_0807 Escherichia coli O157:H7 str. EC4115 periplasmic pilus chaperone family protein YP_002269339.1 828893 R 444450 CDS YP_002269340.1 209399371 6969852 complement(829639..832089) 1 NC_011353.1 identified by match to protein family HMM PF00577; fimbrial usher protein 832089 6969852 ECH74115_0808 Escherichia coli O157:H7 str. EC4115 fimbrial usher protein YP_002269340.1 829639 R 444450 CDS YP_002269341.1 209400772 6970496 complement(832148..832714) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 832714 6970496 ECH74115_0809 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002269341.1 832148 R 444450 CDS YP_002269342.1 209396333 6971997 complement(833101..834384) 1 NC_011353.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 834384 gltA 6971997 gltA Escherichia coli O157:H7 str. EC4115 type II citrate synthase YP_002269342.1 833101 R 444450 CDS YP_002269343.1 209397702 6966621 835078..835482 1 NC_011353.1 succinate dehydrogenase cytochrome b556 large membrane subunit 835482 sdhC 6966621 sdhC Escherichia coli O157:H7 str. EC4115 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002269343.1 835078 D 444450 CDS YP_002269344.1 209396511 6968686 complement(835135..835272) 1 NC_011353.1 hypothetical protein 835272 6968686 ECH74115_0812 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269344.1 835135 R 444450 CDS YP_002269345.1 209398560 6967423 835476..835823 1 NC_011353.1 identified by match to protein family HMM TIGR02968; succinate dehydrogenase cytochrome b556 small membrane subunit 835823 sdhD 6967423 sdhD Escherichia coli O157:H7 str. EC4115 succinate dehydrogenase cytochrome b556 small membrane subunit YP_002269345.1 835476 D 444450 CDS YP_002269346.1 209399318 6969620 835823..837589 1 NC_011353.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 837589 sdhA 6969620 sdhA Escherichia coli O157:H7 str. EC4115 succinate dehydrogenase flavoprotein subunit YP_002269346.1 835823 D 444450 CDS YP_002269347.1 209400050 6970437 837605..838321 1 NC_011353.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 838321 sdhB 6970437 sdhB Escherichia coli O157:H7 str. EC4115 succinate dehydrogenase iron-sulfur subunit YP_002269347.1 837605 D 444450 CDS YP_002269348.1 209398829 6971227 complement(838355..838486) 1 NC_011353.1 hypothetical protein 838486 6971227 ECH74115_0817 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269348.1 838355 R 444450 CDS YP_002269349.1 209399395 6969912 838622..841423 1 NC_011353.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 841423 sucA 6969912 sucA Escherichia coli O157:H7 str. EC4115 2-oxoglutarate dehydrogenase E1 component YP_002269349.1 838622 D 444450 CDS YP_002269350.1 209397255 6970520 841438..842655 1 NC_011353.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 842655 sucB 6970520 sucB Escherichia coli O157:H7 str. EC4115 dihydrolipoamide succinyltransferase YP_002269350.1 841438 D 444450 CDS YP_002269351.1 209397431 6968213 842749..843915 1 NC_011353.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 843915 sucC 6968213 sucC Escherichia coli O157:H7 str. EC4115 succinyl-CoA synthetase subunit beta YP_002269351.1 842749 D 444450 CDS YP_002269352.1 209395766 6968400 843915..844784 1 NC_011353.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 844784 sucD 6968400 sucD Escherichia coli O157:H7 str. EC4115 succinyl-CoA synthetase subunit alpha YP_002269352.1 843915 D 444450 CDS YP_002269353.1 209396674 6966622 845034..845180 1 NC_011353.1 hypothetical protein 845180 6966622 ECH74115_0822 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269353.1 845034 D 444450 CDS YP_002269354.1 209396424 6967595 845451..846356 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 846356 6967595 ECH74115_0823 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002269354.1 845451 D 444450 CDS YP_002269355.1 209399693 6967331 complement(846390..846992) 1 NC_011353.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 846992 cobO 6967331 cobO Escherichia coli O157:H7 str. EC4115 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002269355.1 846390 R 444450 CDS YP_002269356.1 209400924 6970843 complement(847002..848654) 1 NC_011353.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; hydro-lyase, Fe-S type, tartrate/fumarate family 848654 6970843 ECH74115_0825 Escherichia coli O157:H7 str. EC4115 hydro-lyase, Fe-S type, tartrate/fumarate family YP_002269356.1 847002 R 444450 CDS YP_002269357.1 209398852 6972161 complement(848762..850042) 1 NC_011353.1 identified by match to protein family HMM PF00375; transporter dicarboxylate/amino acid:cation family 850042 6972161 ECH74115_0826 Escherichia coli O157:H7 str. EC4115 transporter dicarboxylate/amino acid:cation family YP_002269357.1 848762 R 444450 CDS YP_002269358.1 209398159 6969937 complement(850203..850520) 1 NC_011353.1 hypothetical protein 850520 6969937 ECH74115_0827 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269358.1 850203 R 444450 CDS YP_002269359.1 209395921 6969183 complement(850517..851887) 1 NC_011353.1 hypothetical protein 851887 6969183 ECH74115_0828 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269359.1 850517 R 444450 CDS YP_002269360.1 209396931 6966788 complement(851891..853132) 1 NC_011353.1 identified by match to protein family HMM PF05034; match to protein family HMM PF07476; match to protein family HMM TIGR01502; methylaspartate ammonia-lyase 853132 6966788 ECH74115_0829 Escherichia coli O157:H7 str. EC4115 methylaspartate ammonia-lyase YP_002269360.1 851891 R 444450 CDS YP_002269361.1 209400012 6967869 complement(853132..854577) 1 NC_011353.1 identified by match to protein family HMM PF06368; match to protein family HMM TIGR01503; methylaspartate mutase subunit E 854577 mutE 6967869 mutE Escherichia coli O157:H7 str. EC4115 methylaspartate mutase subunit E YP_002269361.1 853132 R 444450 CDS YP_002269362.1 209399739 6971187 complement(854596..855984) 1 NC_011353.1 identified by match to protein family HMM TIGR01319; glutamate mutase mutL 855984 6971187 ECH74115_0831 Escherichia coli O157:H7 str. EC4115 glutamate mutase mutL YP_002269362.1 854596 R 444450 CDS YP_002269363.1 209400500 6970894 complement(855984..856433) 1 NC_011353.1 converts methylaspartate to L-glutamate; methylaspartate mutase subunit S 856433 mamA 6970894 mamA Escherichia coli O157:H7 str. EC4115 methylaspartate mutase subunit S YP_002269363.1 855984 R 444450 CDS YP_002269364.1 209398431 6971705 complement(856981..857280) 1 NC_011353.1 identified by glimmer; hypothetical protein 857280 6971705 ECH74115_0833 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269364.1 856981 R 444450 CDS YP_002269365.1 209399014 6969479 complement(857485..858312) 1 NC_011353.1 identified by glimmer; hypothetical protein 858312 6969479 ECH74115_0834 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269365.1 857485 R 444450 CDS YP_002269366.1 209397384 6970114 859235..860803 1 NC_011353.1 identified by match to protein family HMM PF01654; cytochrome d ubiquinol oxidase, subunit I 860803 cydA 6970114 cydA Escherichia coli O157:H7 str. EC4115 cytochrome d ubiquinol oxidase, subunit I YP_002269366.1 859235 D 444450 CDS YP_002269367.1 209398213 6968350 860819..861958 1 NC_011353.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome d ubiquinol oxidase, subunit II 861958 cydB1 6968350 cydB1 Escherichia coli O157:H7 str. EC4115 cytochrome d ubiquinol oxidase, subunit II YP_002269367.1 860819 D 444450 CDS YP_002269368.1 209397889 6969242 861973..862086 1 NC_011353.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106; cyd operon protein YbgT 862086 6969242 ECH74115_0837 Escherichia coli O157:H7 str. EC4115 cyd operon protein YbgT YP_002269368.1 861973 D 444450 CDS YP_002269369.1 209397052 6968886 862179..862379 1 NC_011353.1 identified by match to protein family HMM TIGR02112; hypothetical protein 862379 6968886 ECH74115_0838 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269369.1 862179 D 444450 CDS YP_002269370.1 209399625 6967998 862529..862933 1 NC_011353.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 862933 ybgC 6967998 ybgC Escherichia coli O157:H7 str. EC4115 acyl-CoA thioester hydrolase YbgC YP_002269370.1 862529 D 444450 CDS YP_002269371.1 209398857 6970769 862930..863622 1 NC_011353.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 863622 tolQ 6970769 tolQ Escherichia coli O157:H7 str. EC4115 colicin uptake protein TolQ YP_002269371.1 862930 D 444450 CDS YP_002269372.1 209400806 6969942 863626..864054 1 NC_011353.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 864054 tolR 6969942 tolR Escherichia coli O157:H7 str. EC4115 colicin uptake protein TolR YP_002269372.1 863626 D 444450 CDS YP_002269373.1 209400066 6972034 864119..865393 1 NC_011353.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 865393 tolA 6972034 tolA Escherichia coli O157:H7 str. EC4115 cell envelope integrity inner membrane protein TolA YP_002269373.1 864119 D 444450 CDS YP_002269374.1 209399861 6971245 865526..866818 1 NC_011353.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 866818 tolB 6971245 tolB Escherichia coli O157:H7 str. EC4115 translocation protein TolB YP_002269374.1 865526 D 444450 CDS YP_002269375.1 209396423 6971020 866853..867374 1 NC_011353.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802; peptidoglycan-associated outer membrane lipoprotein 867374 pal 6971020 pal Escherichia coli O157:H7 str. EC4115 peptidoglycan-associated outer membrane lipoprotein YP_002269375.1 866853 D 444450 CDS YP_002269376.1 209395711 6967330 867384..868175 1 NC_011353.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 868175 ygbF 6967330 ygbF Escherichia coli O157:H7 str. EC4115 tol-pal system protein YbgF YP_002269376.1 867384 D 444450 CDS YP_002269377.1 209398333 6972398 869319..870353 1 NC_011353.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 870353 nadA 6972398 nadA Escherichia coli O157:H7 str. EC4115 quinolinate synthetase YP_002269377.1 869319 D 444450 CDS YP_002269378.1 209396345 6969373 870391..871110 1 NC_011353.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter PnuC 871110 pnuC 6969373 pnuC Escherichia coli O157:H7 str. EC4115 nicotinamide mononucleotide transporter PnuC YP_002269378.1 870391 D 444450 CDS YP_002269379.1 209397329 6967247 complement(871107..872048) 1 NC_011353.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 872048 zitB 6967247 zitB Escherichia coli O157:H7 str. EC4115 zinc transporter ZitB YP_002269379.1 871107 R 444450 CDS YP_002269380.1 209395790 6968294 complement(872162..872542) 1 NC_011353.1 hypothetical protein 872542 6968294 ECH74115_0855 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269380.1 872162 R 444450 CDS YP_002269381.1 209400570 6966646 872858..873910 1 NC_011353.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 873910 aroG 6966646 aroG Escherichia coli O157:H7 str. EC4115 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002269381.1 872858 D 444450 CDS YP_002269382.1 209400834 6971780 complement(874076..874828) 1 NC_011353.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 874828 gpmA 6971780 gpmA Escherichia coli O157:H7 str. EC4115 phosphoglyceromutase YP_002269382.1 874076 R 444450 CDS YP_002269383.1 209399056 6972064 complement(874902..875030) 1 NC_011353.1 identified by glimmer; hypothetical protein 875030 6972064 ECH74115_0858 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269383.1 874902 R 444450 CDS YP_002269384.1 209398606 6970158 complement(875030..876070) 1 NC_011353.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 876070 galM 6970158 galM Escherichia coli O157:H7 str. EC4115 aldose 1-epimerase YP_002269384.1 875030 R 444450 CDS YP_002269385.1 209398960 6969669 complement(876064..877212) 1 NC_011353.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 877212 galK 6969669 galK Escherichia coli O157:H7 str. EC4115 galactokinase YP_002269385.1 876064 R 444450 CDS YP_002269386.1 209397834 6970055 complement(877216..878262) 1 NC_011353.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 878262 galT 6970055 galT Escherichia coli O157:H7 str. EC4115 galactose-1-phosphate uridylyltransferase YP_002269386.1 877216 R 444450 CDS YP_002269387.1 209397428 6968825 complement(878272..879288) 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-galactose-4-epimerase 879288 galE 6968825 galE Escherichia coli O157:H7 str. EC4115 UDP-galactose-4-epimerase YP_002269387.1 878272 R 444450 CDS YP_002269388.1 209395942 6968397 complement(879550..881022) 1 NC_011353.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 881022 modF 6968397 modF Escherichia coli O157:H7 str. EC4115 molybdenum transport ATP-binding protein ModF YP_002269388.1 879550 R 444450 CDS YP_002269389.1 209400782 6966809 complement(881090..881878) 1 NC_011353.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 881878 modE 6966809 modE Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator ModE YP_002269389.1 881090 R 444450 CDS YP_002269390.1 209400035 6972007 882007..882156 1 NC_011353.1 hypothetical protein 882156 6972007 ECH74115_0865 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269390.1 882007 D 444450 CDS YP_002269391.1 209399552 6971210 882323..883096 1 NC_011353.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 883096 modA 6971210 modA Escherichia coli O157:H7 str. EC4115 molybdate transporter periplasmic protein YP_002269391.1 882323 D 444450 CDS YP_002269392.1 209398963 6970690 883096..883785 1 NC_011353.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 883785 modB 6970690 modB Escherichia coli O157:H7 str. EC4115 molybdate ABC transporter permease YP_002269392.1 883096 D 444450 CDS YP_002269393.1 209398651 6970058 883788..884846 1 NC_011353.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 884846 modC 6970058 modC Escherichia coli O157:H7 str. EC4115 molybdate transporter ATP-binding protein YP_002269393.1 883788 D 444450 CDS YP_002269394.1 209397698 6969720 complement(884847..885767) 1 NC_011353.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 885767 ybhA 6969720 ybhA Escherichia coli O157:H7 str. EC4115 phosphotransferase YP_002269394.1 884847 R 444450 CDS YP_002269395.1 209397419 6968682 885820..886815 1 NC_011353.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 886815 pgl 6968682 pgl Escherichia coli O157:H7 str. EC4115 6-phosphogluconolactonase YP_002269395.1 885820 D 444450 CDS YP_002269396.1 209396612 6968387 complement(886856..887809) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 887809 6968387 ECH74115_0871 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002269396.1 886856 R 444450 CDS YP_002269397.1 209396315 6967531 887791..887907 1 NC_011353.1 identified by glimmer; hypothetical protein 887907 6967531 ECH74115_0872 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269397.1 887791 D 444450 CDS YP_002269398.1 209400887 6967211 887993..889045 1 NC_011353.1 identified by match to protein family HMM PF04303; hypothetical protein 889045 6967211 ECH74115_0873 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269398.1 887993 D 444450 CDS YP_002269399.1 209397894 6972120 889121..890554 1 NC_011353.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785; anion transporter 890554 6972120 ECH74115_0874 Escherichia coli O157:H7 str. EC4115 anion transporter YP_002269399.1 889121 D 444450 CDS YP_002269400.1 209399369 6968892 890737..892998 1 NC_011353.1 identified by match to protein family HMM PF00330; hypothetical protein 892998 6968892 ECH74115_0875 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269400.1 890737 D 444450 CDS YP_002269401.1 209397907 6970494 complement(893139..894422) 1 NC_011353.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase 894422 6970494 ECH74115_0876 Escherichia coli O157:H7 str. EC4115 pectinesterase YP_002269401.1 893139 R 444450 CDS YP_002269402.1 209397327 6968905 complement(894557..895627) 1 NC_011353.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM PF09003; phage integrase family protein 895627 6968905 ECH74115_0877 Escherichia coli O157:H7 str. EC4115 phage integrase family protein YP_002269402.1 894557 R 444450 CDS YP_002269403.1 209399394 6968291 895875..896045 1 NC_011353.1 identified by glimmer; hypothetical protein 896045 6968291 ECH74115_0878 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269403.1 895875 D 444450 CDS YP_002269404.1 209398831 6970519 896332..896454 1 NC_011353.1 hypothetical protein 896454 6970519 ECH74115_0879 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269404.1 896332 D 444450 CDS YP_002269405.1 209400922 6969914 896726..896875 1 NC_011353.1 hypothetical protein 896875 6969914 ECH74115_0880 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269405.1 896726 D 444450 CDS YP_002269406.1 209400339 6972159 complement(897406..897621) 1 NC_011353.1 hypothetical protein 897621 6972159 ECH74115_0881 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269406.1 897406 R 444450 CDS YP_002269407.1 209397067 6971536 complement(897698..897889) 1 NC_011353.1 identified by match to protein family HMM PF07131; hypothetical protein 897889 6971536 ECH74115_0882 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269407.1 897698 R 444450 CDS YP_002269408.1 209396861 6968013 complement(898041..898721) 1 NC_011353.1 identified by match to protein family HMM PF09588; exonuclease 898721 exo 6968013 exo Escherichia coli O157:H7 str. EC4115 exonuclease YP_002269408.1 898041 R 444450 CDS YP_002269409.1 209397607 6967796 complement(898718..899365) 1 NC_011353.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; recombination protein bet 899365 6967796 ECH74115_0884 Escherichia coli O157:H7 str. EC4115 recombination protein bet YP_002269409.1 898718 R 444450 CDS YP_002269410.1 209398145 6968588 899758..900381 1 NC_011353.1 identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein 900381 6968588 ECH74115_0885 Escherichia coli O157:H7 str. EC4115 bacteriophage Lambda NinG protein YP_002269410.1 899758 D 444450 CDS YP_002269411.1 209400061 6969168 900378..901043 1 NC_011353.1 identified by match to protein family HMM PF00149; serine/threonine-protein phosphatase 1 901043 6969168 ECH74115_0886 Escherichia coli O157:H7 str. EC4115 serine/threonine-protein phosphatase 1 YP_002269411.1 900378 D 444450 CDS YP_002269412.1 209400829 6971240 complement(901255..902214) 1 NC_011353.1 outer membrane protein 902214 6971240 ECH74115_0887 Escherichia coli O157:H7 str. EC4115 outer membrane protein YP_002269412.1 901255 R 444450 CDS YP_002269413.1 209396521 6972057 902689..903378 1 NC_011353.1 identified by match to protein family HMM PF06323; anti-termination protein 903378 6972057 ECH74115_0888 Escherichia coli O157:H7 str. EC4115 anti-termination protein YP_002269413.1 902689 D 444450 CDS YP_002269414.1 209399729 6967434 903589..904305 1 NC_011353.1 hypothetical protein 904305 6967434 ECH74115_0889 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269414.1 903589 D 444450 CDS YP_002269415.1 209397854 6970882 904391..904549 1 NC_011353.1 hypothetical protein 904549 6970882 ECH74115_0890 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269415.1 904391 D 444450 CDS YP_002269416.1 209399665 6967108 905386..905883 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 905883 6967108 ECH74115_0892 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002269416.1 905386 D 444450 CDS YP_002269417.1 209400480 6970812 905880..906347 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 906347 6970812 ECH74115_0893 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002269417.1 905880 D 444450 CDS YP_002269418.1 209400716 6971685 906335..906487 1 NC_011353.1 hypothetical protein 906487 6971685 ECH74115_0894 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269418.1 906335 D 444450 CDS YP_002269419.1 209399312 6971940 907162..907653 1 NC_011353.1 identified by match to protein family HMM PF07278; bacteriophage DNA packaging protein; terminase, small subunit 907653 6971940 ECH74115_0895 Escherichia coli O157:H7 str. EC4115 bacteriophage DNA packaging protein; terminase, small subunit YP_002269419.1 907162 D 444450 CDS YP_002269420.1 209400447 6970430 907653..909755 1 NC_011353.1 identified by match to protein family HMM PF05876; phage terminase large subunit 909755 6970430 ECH74115_0896 Escherichia coli O157:H7 str. EC4115 phage terminase large subunit YP_002269420.1 907653 D 444450 CDS YP_002269421.1 209398562 6971652 909752..909964 1 NC_011353.1 hypothetical protein 909964 6971652 ECH74115_0897 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269421.1 909752 D 444450 CDS YP_002269422.1 209397527 6967957 911487..913445 1 NC_011353.1 identified by match to protein family HMM PF00574; Clp protease domain-containing protein 913445 clpP 6967957 clpP Escherichia coli O157:H7 str. EC4115 Clp protease domain-containing protein YP_002269422.1 911487 D 444450 CDS YP_002269423.1 209397736 6968500 913532..913855 1 NC_011353.1 hypothetical protein 913855 6968500 ECH74115_0901 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269423.1 913532 D 444450 CDS YP_002269424.1 209396691 6968721 913848..914123 1 NC_011353.1 hypothetical protein 914123 6968721 ECH74115_0902 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269424.1 913848 D 444450 CDS YP_002269425.1 209400183 6967613 914135..914713 1 NC_011353.1 identified by match to protein family HMM PF06763; prophage minor tail protein Z 914713 6967613 ECH74115_0903 Escherichia coli O157:H7 str. EC4115 prophage minor tail protein Z YP_002269425.1 914135 D 444450 CDS YP_002269426.1 209395971 6971370 914710..915111 1 NC_011353.1 identified by match to protein family HMM PF06141; phage minor tail protein U 915111 6971370 ECH74115_0904 Escherichia coli O157:H7 str. EC4115 phage minor tail protein U YP_002269426.1 914710 D 444450 CDS YP_002269427.1 209396070 6966840 915122..915865 1 NC_011353.1 identified by match to protein family HMM PF02368; gp13 915865 6966840 ECH74115_0905 Escherichia coli O157:H7 str. EC4115 gp13 YP_002269427.1 915122 D 444450 CDS YP_002269428.1 209400155 6966949 915926..916312 1 NC_011353.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 916312 6966949 ECH74115_0906 Escherichia coli O157:H7 str. EC4115 phage minor tail protein G YP_002269428.1 915926 D 444450 CDS YP_002269429.1 209395896 6971341 916333..916650 1 NC_011353.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 916650 6971341 ECH74115_0907 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002269429.1 916333 D 444450 CDS YP_002269430.1 209396645 6966762 916622..919687 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 919687 6966762 ECH74115_0908 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002269430.1 916622 D 444450 CDS YP_002269431.1 209397074 6967565 919687..920016 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 920016 6967565 ECH74115_0909 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002269431.1 919687 D 444450 CDS YP_002269432.1 209397113 6968020 920026..920724 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 920724 6968020 ECH74115_0910 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002269432.1 920026 D 444450 CDS YP_002269433.1 209397853 6968062 920730..921473 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 921473 6968062 ECH74115_0911 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002269433.1 920730 D 444450 CDS YP_002269434.1 209398886 6968845 921506..922018 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 922018 6968845 ECH74115_0912 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002269434.1 921506 D 444450 CDS YP_002269435.1 209399520 6969975 922079..925492 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 925492 6969975 ECH74115_0913 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269435.1 922079 D 444450 CDS YP_002269436.1 209396045 6970656 925563..926162 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 926162 6970656 ECH74115_0914 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002269436.1 925563 D 444450 CDS YP_002269437.1 209398128 6966921 926222..927538 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 927538 6966921 ECH74115_0915 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002269437.1 926222 D 444450 CDS YP_002269438.1 209400364 6969150 927540..927809 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 927809 6969150 ECH74115_0916 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002269438.1 927540 D 444450 CDS YP_002269439.1 209400256 6971562 927986..928966 1 NC_011353.1 non-LEE-encoded effector NleB 928966 6971562 ECH74115_0917 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector NleB YP_002269439.1 927986 D 444450 CDS YP_002269440.1 209399509 6971448 929027..930019 1 NC_011353.1 non-LEE encoded type III effector C 930019 6971448 ECH74115_0918 Escherichia coli O157:H7 str. EC4115 non-LEE encoded type III effector C YP_002269440.1 929027 D 444450 CDS YP_002269441.1 209398763 6970644 930847..931728 1 NC_011353.1 non-LEE-encoded effector NleH 931728 6970644 ECH74115_0919 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector NleH YP_002269441.1 930847 D 444450 CDS YP_002269442.1 209397270 6968377 complement(933164..933640) 1 NC_011353.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 933640 6968377 ECH74115_0921 Escherichia coli O157:H7 str. EC4115 kinase inhibitor protein YP_002269442.1 933164 R 444450 CDS YP_002269443.1 209396522 6968230 complement(933699..935099) 1 NC_011353.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 935099 bioA 6968230 bioA Escherichia coli O157:H7 str. EC4115 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002269443.1 933699 R 444450 CDS YP_002269444.1 209401003 6967435 935075..936115 1 NC_011353.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthase 936115 bioB 6967435 bioB Escherichia coli O157:H7 str. EC4115 biotin synthase YP_002269444.1 935075 D 444450 CDS YP_002269445.1 209398877 6972245 936112..937266 1 NC_011353.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 937266 bioF 6972245 bioF Escherichia coli O157:H7 str. EC4115 8-amino-7-oxononanoate synthase YP_002269445.1 936112 D 444450 CDS YP_002269446.1 209399655 6969964 937253..938008 1 NC_011353.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 938008 bioC 6969964 bioC Escherichia coli O157:H7 str. EC4115 biotin biosynthesis protein BioC YP_002269446.1 937253 D 444450 CDS YP_002269447.1 209397953 6970801 938001..938678 1 NC_011353.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 938678 bioD 6970801 bioD Escherichia coli O157:H7 str. EC4115 dithiobiotin synthetase YP_002269447.1 938001 D 444450 CDS YP_002269448.1 209398352 6968958 939257..941278 1 NC_011353.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 941278 uvrB 6968958 uvrB Escherichia coli O157:H7 str. EC4115 excinuclease ABC subunit B YP_002269448.1 939257 D 444450 CDS YP_002269449.1 209397385 6969392 complement(941469..942377) 1 NC_011353.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein 942377 6969392 ECH74115_0928 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269449.1 941469 R 444450 CDS YP_002269450.1 209398143 6968351 942774..943763 1 NC_011353.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 943763 moaA 6968351 moaA Escherichia coli O157:H7 str. EC4115 molybdenum cofactor biosynthesis protein A YP_002269450.1 942774 D 444450 CDS YP_002269451.1 209400936 6969166 943785..944297 1 NC_011353.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667; molybdenum cofactor biosynthesis protein B 944297 moaB 6969166 moaB Escherichia coli O157:H7 str. EC4115 molybdenum cofactor biosynthesis protein B YP_002269451.1 943785 D 444450 CDS YP_002269452.1 209396020 6972173 944300..944785 1 NC_011353.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 944785 moaC 6972173 moaC Escherichia coli O157:H7 str. EC4115 molybdenum cofactor biosynthesis protein MoaC YP_002269452.1 944300 D 444450 CDS YP_002269453.1 209399142 6966893 944778..945023 1 NC_011353.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 945023 moaD 6966893 moaD Escherichia coli O157:H7 str. EC4115 molybdopterin synthase small subunit YP_002269453.1 944778 D 444450 CDS YP_002269454.1 209397551 6970248 945025..945477 1 NC_011353.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 945477 moaE 6970248 moaE Escherichia coli O157:H7 str. EC4115 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_002269454.1 945025 D 444450 CDS YP_002269455.1 209400563 6968525 945613..946317 1 NC_011353.1 identified by match to protein family HMM PF01027; hypothetical protein 946317 6968525 ECH74115_0934 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269455.1 945613 D 444450 CDS YP_002269456.1 209398696 6971772 946525..947238 1 NC_011353.1 identified by match to protein family HMM PF01027; hypothetical protein 947238 6971772 ECH74115_0935 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269456.1 946525 D 444450 CDS YP_002269457.1 209400944 6969768 complement(947274..948230) 1 NC_011353.1 hypothetical protein 948230 6969768 ECH74115_0936 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269457.1 947274 R 444450 CDS YP_002269458.1 209400411 6972181 complement(948230..949471) 1 NC_011353.1 identified by match to protein family HMM PF00614; cardiolipin synthase 2 949471 6972181 ECH74115_0937 Escherichia coli O157:H7 str. EC4115 cardiolipin synthase 2 YP_002269458.1 948230 R 444450 CDS YP_002269459.1 209396778 6971612 complement(949468..950229) 1 NC_011353.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family protein 950229 6971612 ECH74115_0938 Escherichia coli O157:H7 str. EC4115 endonuclease/exonuclease/phosphatase family protein YP_002269459.1 949468 R 444450 CDS YP_002269460.1 209397275 6967708 950362..950772 1 NC_011353.1 hypothetical protein 950772 6967708 ECH74115_0940 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269460.1 950362 D 444450 CDS YP_002269461.1 209400178 6968236 complement(950734..951840) 1 NC_011353.1 identified by match to protein family HMM PF01061; ABC-2 type transporter permease 951840 6968236 ECH74115_0939 Escherichia coli O157:H7 str. EC4115 ABC-2 type transporter permease YP_002269461.1 950734 R 444450 CDS YP_002269462.1 209397925 6971365 complement(951851..952984) 1 NC_011353.1 identified by match to protein family HMM PF01061; ABC-2 type transporter permease 952984 6971365 ECH74115_0941 Escherichia coli O157:H7 str. EC4115 ABC-2 type transporter permease YP_002269462.1 951851 R 444450 CDS YP_002269463.1 209398784 6968925 complement(952977..954713) 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 954713 6968925 ECH74115_0942 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002269463.1 952977 R 444450 CDS YP_002269464.1 209398015 6969862 complement(954706..955701) 1 NC_011353.1 identified by match to protein family HMM PF00529; hypothetical protein 955701 6969862 ECH74115_0943 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269464.1 954706 R 444450 CDS YP_002269465.1 209400271 6969028 complement(955704..956375) 1 NC_011353.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209; DNA-binding transcriptional regulator 956375 6969028 ECH74115_0944 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002269465.1 955704 R 444450 CDS YP_002269466.1 209396359 6971464 956604..957971 1 NC_011353.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 957971 6971464 ECH74115_0945 Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase RhlE YP_002269466.1 956604 D 444450 CDS YP_002269467.1 209400208 6967261 958123..958266 1 NC_011353.1 identified by glimmer; hypothetical protein 958266 6967261 ECH74115_0946 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269467.1 958123 D 444450 CDS YP_002269468.1 209396431 6971396 958579..960591 1 NC_011353.1 identified by glimmer; hypothetical protein 960591 6971396 ECH74115_0947 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269468.1 958579 D 444450 CDS YP_002269469.1 209398717 6967338 960737..963025 1 NC_011353.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 963025 dinG 6967338 dinG Escherichia coli O157:H7 str. EC4115 ATP-dependent DNA helicase DinG YP_002269469.1 960737 D 444450 CDS YP_002269470.1 209400968 6969789 963053..964015 1 NC_011353.1 identified by match to protein family HMM PF02885; glycosyl transferase family protein 964015 6969789 ECH74115_0949 Escherichia coli O157:H7 str. EC4115 glycosyl transferase family protein YP_002269470.1 963053 D 444450 CDS YP_002269471.1 209397893 6972208 964156..965241 1 NC_011353.1 identified by match to protein family HMM PF02615; hypothetical protein 965241 6972208 ECH74115_0950 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269471.1 964156 D 444450 CDS YP_002269472.1 209397304 6968891 complement(965470..965730) 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 965730 6968891 ECH74115_0951 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269472.1 965470 R 444450 CDS YP_002269473.1 209396378 6968265 complement(965995..966261) 1 NC_011353.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; hypothetical protein 966261 6968265 ECH74115_0952 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269473.1 965995 R 444450 CDS YP_002269474.1 209398451 6967283 complement(966335..967021) 1 NC_011353.1 identified by match to protein family HMM PF03171; hydroxylase 967021 6967283 ECH74115_0953 Escherichia coli O157:H7 str. EC4115 hydroxylase YP_002269474.1 966335 R 444450 CDS YP_002269475.1 209397104 6969504 complement(967063..969345) 1 NC_011353.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 969345 fiu 6969504 fiu Escherichia coli O157:H7 str. EC4115 catecholate siderophore receptor Fiu YP_002269475.1 967063 R 444450 CDS YP_002269476.1 209397684 6968053 complement(969610..969870) 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 969870 6968053 ECH74115_0955 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269476.1 969610 R 444450 CDS YP_002269477.1 209396578 6968667 970146..971072 1 NC_011353.1 identified by match to protein family HMM PF05971; SAM-dependent methyltransferase 971072 6968667 ECH74115_0957 Escherichia coli O157:H7 str. EC4115 SAM-dependent methyltransferase YP_002269477.1 970146 D 444450 CDS YP_002269478.1 209395963 6967493 complement(971069..973294) 1 NC_011353.1 identified by match to protein family HMM PF00924; hypothetical protein 973294 6967493 ECH74115_0956 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269478.1 971069 R 444450 CDS YP_002269479.1 209398944 6966830 complement(973411..974133) 1 NC_011353.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 974133 glnQ 6966830 glnQ Escherichia coli O157:H7 str. EC4115 glutamine ABC transporter ATP-binding protein YP_002269479.1 973411 R 444450 CDS YP_002269480.1 209399532 6970038 complement(974130..974789) 1 NC_011353.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 974789 glnP 6970038 glnP Escherichia coli O157:H7 str. EC4115 glutamine ABC transporter permease YP_002269480.1 974130 R 444450 CDS YP_002269481.1 209397153 6970668 complement(974927..975673) 1 NC_011353.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 975673 glnH 6970668 glnH Escherichia coli O157:H7 str. EC4115 glutamine ABC transporter periplasmic protein YP_002269481.1 974927 R 444450 CDS YP_002269482.1 209397746 6968105 complement(976077..976580) 1 NC_011353.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 976580 dps 6968105 dps Escherichia coli O157:H7 str. EC4115 DNA starvation/stationary phase protection protein Dps YP_002269482.1 976077 R 444450 CDS YP_002269483.1 209396405 6968731 complement(976879..977778) 1 NC_011353.1 identified by match to protein family HMM PF00892; threonine and homoserine efflux system 977778 rhtA 6968731 rhtA Escherichia coli O157:H7 str. EC4115 threonine and homoserine efflux system YP_002269483.1 976879 R 444450 CDS YP_002269484.1 209400925 6967312 978119..978634 1 NC_011353.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 978634 ompX 6967312 ompX Escherichia coli O157:H7 str. EC4115 outer membrane protein X YP_002269484.1 978119 D 444450 CDS YP_002269485.1 209398680 6972162 complement(978683..980266) 1 NC_011353.1 identified by match to protein family HMM PF00884; sulfatase family protein 980266 6972162 ECH74115_0964 Escherichia coli O157:H7 str. EC4115 sulfatase family protein YP_002269485.1 978683 R 444450 CDS YP_002269486.1 209399111 6970587 980852..981319 1 NC_011353.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 981319 mntR 6970587 mntR Escherichia coli O157:H7 str. EC4115 manganese transport regulator MntR YP_002269486.1 980852 D 444450 CDS YP_002269487.1 209399705 6970213 981316..982434 1 NC_011353.1 identified by match to protein family HMM PF03600; citrate transporter family protein 982434 6970213 ECH74115_0967 Escherichia coli O157:H7 str. EC4115 citrate transporter family protein YP_002269487.1 981316 D 444450 CDS YP_002269488.1 209397897 6970856 complement(982492..983406) 1 NC_011353.1 identified by match to protein family HMM PF03734; hypothetical protein 983406 ybiS 6970856 ybiS Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269488.1 982492 R 444450 CDS YP_002269489.1 209398822 6968895 983631..985223 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 985223 6968895 ECH74115_0969 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002269489.1 983631 D 444450 CDS YP_002269490.1 209397491 6969905 complement(985391..986656) 1 NC_011353.1 identified by match to protein family HMM PF07350; hypothetical protein 986656 6969905 ECH74115_0970 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269490.1 985391 R 444450 CDS YP_002269491.1 209398068 6968462 complement(986808..987623) 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; sugar phosphatase SupH 987623 supH 6968462 supH Escherichia coli O157:H7 str. EC4115 sugar phosphatase SupH YP_002269491.1 986808 R 444450 CDS YP_002269492.1 209400385 6967099 complement(990206..991105) 1 NC_011353.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating protein 991105 6967099 ECH74115_0974 Escherichia coli O157:H7 str. EC4115 glycyl-radical enzyme activating protein YP_002269492.1 990206 R 444450 CDS YP_002269493.1 209399785 6971586 991236..991898 1 NC_011353.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 991898 fsaA 6971586 fsaA Escherichia coli O157:H7 str. EC4115 fructose-6-phosphate aldolase YP_002269493.1 991236 D 444450 CDS YP_002269494.1 209399331 6970942 complement(992077..992826) 1 NC_011353.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 992826 moeB 6970942 moeB Escherichia coli O157:H7 str. EC4115 molybdopterin biosynthesis protein MoeB YP_002269494.1 992077 R 444450 CDS YP_002269495.1 209398772 6970451 complement(992826..994061) 1 NC_011353.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 994061 moeA 6970451 moeA Escherichia coli O157:H7 str. EC4115 molybdopterin biosynthesis protein MoeA YP_002269495.1 992826 R 444450 CDS YP_002269496.1 209400349 6967896 995199..997088 1 NC_011353.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 997088 gsiA 6967896 gsiA Escherichia coli O157:H7 str. EC4115 glutathione transporter ATP-binding protein YP_002269496.1 995199 D 444450 CDS YP_002269497.1 209399726 6971547 997108..998646 1 NC_011353.1 identified by match to protein family HMM PF00496; glutathione ABC transporter periplasmic glutathione-binding protein GsiB 998646 gsiB 6971547 gsiB Escherichia coli O157:H7 str. EC4115 glutathione ABC transporter periplasmic glutathione-binding protein GsiB YP_002269497.1 997108 D 444450 CDS YP_002269498.1 209399916 6970879 998664..999584 1 NC_011353.1 identified by match to protein family HMM PF00528; glutathione ABC transporter permease GsiC 999584 gsiC 6970879 gsiC Escherichia coli O157:H7 str. EC4115 glutathione ABC transporter permease GsiC YP_002269498.1 998664 D 444450 CDS YP_002269499.1 209398764 6971080 999587..1000498 1 NC_011353.1 identified by match to protein family HMM PF00528; glutathione ABC transporter permease GsiD 1000498 gsiD 6971080 gsiD Escherichia coli O157:H7 str. EC4115 glutathione ABC transporter permease GsiD YP_002269499.1 999587 D 444450 CDS YP_002269500.1 209398618 6969842 1000676..1003024 1 NC_011353.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 1003024 6969842 ECH74115_0984 Escherichia coli O157:H7 str. EC4115 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein YP_002269500.1 1000676 D 444450 CDS YP_002269501.1 209400162 6969681 1003119..1004360 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1004360 6969681 ECH74115_0985 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002269501.1 1003119 D 444450 CDS YP_002269502.1 209395833 6971348 complement(1004430..1004759) 1 NC_011353.1 identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein 1004759 6971348 ECH74115_0986 Escherichia coli O157:H7 str. EC4115 helix-turn-helix DNA-binding domain-containing protein YP_002269502.1 1004430 R 444450 CDS YP_002269503.1 209396385 6966690 complement(1004749..1005135) 1 NC_011353.1 identified by match to protein family HMM PF06296; hypothetical protein 1005135 6966690 ECH74115_0987 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269503.1 1004749 R 444450 CDS YP_002269504.1 209397285 6967290 complement(1005361..1006686) 1 NC_011353.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; 30S ribosomal protein S12 methylthiotransferase 1006686 rimO 6967290 rimO Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S12 methylthiotransferase YP_002269504.1 1005361 R 444450 CDS YP_002269505.1 209398000 6968246 1006899..1007282 1 NC_011353.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1007282 bssR 6968246 bssR Escherichia coli O157:H7 str. EC4115 biofilm formation regulatory protein BssR YP_002269505.1 1006899 D 444450 CDS YP_002269506.1 209399419 6969011 1007393..1008508 1 NC_011353.1 identified by match to protein family HMM PF07995; glucose / sorbosone dehydrogenase 1008508 6969011 ECH74115_0991 Escherichia coli O157:H7 str. EC4115 glucose / sorbosone dehydrogenase YP_002269506.1 1007393 D 444450 CDS YP_002269507.1 209398814 6970545 complement(1008505..1009131) 1 NC_011353.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase family protein 1009131 6970545 ECH74115_0990 Escherichia coli O157:H7 str. EC4115 glutathione S-transferase family protein YP_002269507.1 1008505 R 444450 CDS YP_002269508.1 209400303 6969894 1009368..1010579 1 NC_011353.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1010579 dacC 6969894 dacC Escherichia coli O157:H7 str. EC4115 D-alanyl-D-alanine carboxypeptidase YP_002269508.1 1009368 D 444450 CDS YP_002269509.1 209399662 6971498 complement(1010626..1011384) 1 NC_011353.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; DNA-binding transcriptional repressor DeoR 1011384 deoR 6971498 deoR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor DeoR YP_002269509.1 1010626 R 444450 CDS YP_002269510.1 209399032 6970809 complement(1011442..1012038) 1 NC_011353.1 identified by match to protein family HMM PF01569; undecaprenyl pyrophosphate phosphatase 1012038 6970809 ECH74115_0994 Escherichia coli O157:H7 str. EC4115 undecaprenyl pyrophosphate phosphatase YP_002269510.1 1011442 R 444450 CDS YP_002269511.1 209400914 6970133 1012323..1013555 1 NC_011353.1 identified by match to protein family HMM PF07690; multidrug translocase MdfA 1013555 mdfA 6970133 mdfA Escherichia coli O157:H7 str. EC4115 multidrug translocase MdfA YP_002269511.1 1012323 D 444450 CDS YP_002269512.1 209400515 6972150 complement(1013596..1013874) 1 NC_011353.1 hypothetical protein 1013874 6972150 ECH74115_0996 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269512.1 1013596 R 444450 CDS YP_002269513.1 209399927 6971722 complement(1013966..1014781) 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YbjI 1014781 ybjI 6971722 ybjI Escherichia coli O157:H7 str. EC4115 phosphatase YbjI YP_002269513.1 1013966 R 444450 CDS YP_002269514.1 209397864 6971092 complement(1014781..1015989) 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1015989 6971092 ECH74115_0998 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002269514.1 1014781 R 444450 CDS YP_002269515.1 209397291 6968856 1016073..1016609 1 NC_011353.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1016609 6968856 ECH74115_0999 Escherichia coli O157:H7 str. EC4115 TetR family transcriptional regulator YP_002269515.1 1016073 D 444450 CDS YP_002269516.1 209399356 6972313 complement(1016784..1018469) 1 NC_011353.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein 1018469 6972313 ECH74115_1001 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269516.1 1016784 R 444450 CDS YP_002269517.1 209398788 6970477 1018739..1019116 1 NC_011353.1 hypothetical protein 1019116 6970477 ECH74115_1002 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269517.1 1018739 D 444450 CDS YP_002269518.1 209398497 6969866 complement(1019146..1019403) 1 NC_011353.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1019403 grxA 6969866 grxA Escherichia coli O157:H7 str. EC4115 glutaredoxin YP_002269518.1 1019146 R 444450 CDS YP_002269519.1 209398233 6969555 1019563..1019850 1 NC_011353.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1019850 6969555 ECH74115_1004 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269519.1 1019563 D 444450 CDS YP_002269520.1 209396034 6969264 1019834..1020556 1 NC_011353.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1020556 nfsA 6969264 nfsA Escherichia coli O157:H7 str. EC4115 nitroreductase A YP_002269520.1 1019834 D 444450 CDS YP_002269521.1 209396739 6966910 1020617..1021519 1 NC_011353.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1021519 rimK 6966910 rimK Escherichia coli O157:H7 str. EC4115 ribosomal protein S6 modification protein YP_002269521.1 1020617 D 444450 CDS YP_002269522.1 209397847 6967665 1021607..1022083 1 NC_011353.1 hypothetical protein 1022083 6967665 ECH74115_1007 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269522.1 1021607 D 444450 CDS YP_002269523.1 209398864 6968839 1022040..1022162 1 NC_011353.1 identified by glimmer; hypothetical protein 1022162 6968839 ECH74115_1008 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269523.1 1022040 D 444450 CDS YP_002269524.1 209397481 6967830 1022434..1023546 1 NC_011353.1 identified by match to protein family HMM PF01547; putrescine ABC transporter periplasmic-binding protein 1023546 potF 6967830 potF Escherichia coli O157:H7 str. EC4115 putrescine ABC transporter periplasmic-binding protein YP_002269524.1 1022434 D 444450 CDS YP_002269525.1 209400780 6968452 1023641..1024774 1 NC_011353.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 1024774 potG 6968452 potG Escherichia coli O157:H7 str. EC4115 putrescine ABC transporter ATP-binding protein YP_002269525.1 1023641 D 444450 CDS YP_002269526.1 209396848 6972005 1024784..1025737 1 NC_011353.1 identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 1025737 potH 6972005 potH Escherichia coli O157:H7 str. EC4115 putrescine ABC transporter membrane protein YP_002269526.1 1024784 D 444450 CDS YP_002269527.1 209399758 6967781 1025734..1026579 1 NC_011353.1 identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 1026579 potI 6967781 potI Escherichia coli O157:H7 str. EC4115 putrescine ABC transporter membrane protein YP_002269527.1 1025734 D 444450 CDS YP_002269528.1 209397452 6970914 1026639..1027127 1 NC_011353.1 hypothetical protein 1027127 6970914 ECH74115_1014 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269528.1 1026639 D 444450 CDS YP_002269529.1 209399215 6968423 1027168..1028295 1 NC_011353.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1028295 rumB 6968423 rumB Escherichia coli O157:H7 str. EC4115 23S rRNA methyluridine methyltransferase YP_002269529.1 1027168 D 444450 CDS YP_002269530.1 209398665 6970325 1028575..1029918 1 NC_011353.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1029918 6970325 ECH74115_1016 Escherichia coli O157:H7 str. EC4115 PTS system ascorbate-specific transporter subunit IIC YP_002269530.1 1028575 D 444450 CDS YP_002269531.1 209399668 6970024 1030272..1031753 1 NC_011353.1 identified by match to protein family HMM PF00884; sulfatase 1031753 6970024 ECH74115_1018 Escherichia coli O157:H7 str. EC4115 sulfatase YP_002269531.1 1030272 D 444450 CDS YP_002269532.1 209400027 6970815 complement(1031804..1032535) 1 NC_011353.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter periplasmic substrate-binding protein ArtJ 1032535 artJ 6970815 artJ Escherichia coli O157:H7 str. EC4115 arginine ABC transporter periplasmic substrate-binding protein ArtJ YP_002269532.1 1031804 R 444450 CDS YP_002269533.1 209396948 6971202 complement(1032689..1032826) 1 NC_011353.1 hypothetical protein 1032826 6971202 ECH74115_1020 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269533.1 1032689 R 444450 CDS YP_002269534.1 209396120 6967886 complement(1032826..1033494) 1 NC_011353.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 1033494 artM 6967886 artM Escherichia coli O157:H7 str. EC4115 arginine transporter permease subunit ArtM YP_002269534.1 1032826 R 444450 CDS YP_002269535.1 209398007 6967000 complement(1033494..1034210) 1 NC_011353.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 1034210 artQ 6967000 artQ Escherichia coli O157:H7 str. EC4115 arginine transporter permease subunit ArtQ YP_002269535.1 1033494 R 444450 CDS YP_002269536.1 209397117 6969019 complement(1034217..1034948) 1 NC_011353.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter substrate-binding protein 1034948 artI 6969019 artI Escherichia coli O157:H7 str. EC4115 arginine ABC transporter substrate-binding protein YP_002269536.1 1034217 R 444450 CDS YP_002269537.1 209399456 6968066 complement(1034966..1035694) 1 NC_011353.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1035694 artP 6968066 artP Escherichia coli O157:H7 str. EC4115 arginine transporter ATP-binding subunit YP_002269537.1 1034966 R 444450 CDS YP_002269538.1 209398500 6970585 complement(1035912..1036427) 1 NC_011353.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 1036427 6970585 ECH74115_1025 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269538.1 1035912 R 444450 CDS YP_002269539.1 209397748 6969558 1037051..1038850 1 NC_011353.1 identified by glimmer; hypothetical protein 1038850 6969558 ECH74115_1026 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269539.1 1037051 D 444450 CDS YP_002269540.1 209397960 6968734 1039061..1039384 1 NC_011353.1 identified by match to protein family HMM PF01906; hypothetical protein 1039384 6968734 ECH74115_1027 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269540.1 1039061 D 444450 CDS YP_002269541.1 209396134 6968965 1039381..1040211 1 NC_011353.1 identified by match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase AmiD 1040211 amiD 6968965 amiD Escherichia coli O157:H7 str. EC4115 N-acetylmuramoyl-L-alanine amidase AmiD YP_002269541.1 1039381 D 444450 CDS YP_002269542.1 209396994 6967017 complement(1040208..1041257) 1 NC_011353.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase family protein 1041257 6967017 ECH74115_1028 Escherichia coli O157:H7 str. EC4115 NAD dependent epimerase/dehydratase family protein YP_002269542.1 1040208 R 444450 CDS YP_002269543.1 209395955 6967936 complement(1041320..1042750) 1 NC_011353.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; NAD dependent epimerase/dehydratase family protein 1042750 6967936 ECH74115_1030 Escherichia coli O157:H7 str. EC4115 NAD dependent epimerase/dehydratase family protein YP_002269543.1 1041320 R 444450 CDS YP_002269544.1 209400875 6966822 complement(1042761..1043762) 1 NC_011353.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 1043762 ltaE 6966822 ltaE Escherichia coli O157:H7 str. EC4115 L-threonine aldolase YP_002269544.1 1042761 R 444450 CDS YP_002269545.1 209400223 6972107 complement(1043799..1045517) 1 NC_011353.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 1045517 poxB 6972107 poxB Escherichia coli O157:H7 str. EC4115 pyruvate dehydrogenase YP_002269545.1 1043799 R 444450 CDS YP_002269546.1 209399450 6971411 complement(1045650..1046618) 1 NC_011353.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; HCP oxidoreductase 1046618 hcr 6971411 hcr Escherichia coli O157:H7 str. EC4115 HCP oxidoreductase YP_002269546.1 1045650 R 444450 CDS YP_002269547.1 209398927 6970579 complement(1046630..1048282) 1 NC_011353.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1048282 hcp 6970579 hcp Escherichia coli O157:H7 str. EC4115 hydroxylamine reductase YP_002269547.1 1046630 R 444450 CDS YP_002269548.1 209398980 6970020 complement(1048426..1049325) 1 NC_011353.1 identified by match to protein family HMM PF03956; hypothetical protein 1049325 6970020 ECH74115_1035 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269548.1 1048426 R 444450 CDS YP_002269549.1 209397737 6970079 complement(1049783..1050478) 1 NC_011353.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1050478 aqpZ 6970079 aqpZ Escherichia coli O157:H7 str. EC4115 aquaporin Z YP_002269549.1 1049783 R 444450 CDS YP_002269550.1 209396552 6968722 1050904..1052562 1 NC_011353.1 hypothetical protein 1052562 6968722 ECH74115_1038 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269550.1 1050904 D 444450 CDS YP_002269551.1 209397130 6967466 complement(1052559..1053551) 1 NC_011353.1 identified by match to protein family HMM PF04393; hypothetical protein 1053551 6967466 ECH74115_1037 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269551.1 1052559 R 444450 CDS YP_002269552.1 209396080 6968079 1053666..1054781 1 NC_011353.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1054781 macA 6968079 macA Escherichia coli O157:H7 str. EC4115 macrolide transporter subunit MacA YP_002269552.1 1053666 D 444450 CDS YP_002269553.1 209395862 6966959 1054778..1056724 1 NC_011353.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1056724 macB 6966959 macB Escherichia coli O157:H7 str. EC4115 macrolide transporter ATP-binding /permease YP_002269553.1 1054778 D 444450 CDS YP_002269554.1 209400231 6966723 complement(1056797..1057021) 1 NC_011353.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 1057021 cspD 6966723 cspD Escherichia coli O157:H7 str. EC4115 stationary phase/starvation inducible regulatory protein CspD YP_002269554.1 1056797 R 444450 CDS YP_002269555.1 209399503 6971421 1057344..1057664 1 NC_011353.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1057664 clpS 6971421 clpS Escherichia coli O157:H7 str. EC4115 ATP-dependent Clp protease adaptor protein ClpS YP_002269555.1 1057344 D 444450 CDS YP_002269556.1 209399660 6970638 1057695..1059971 1 NC_011353.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1059971 clpA 6970638 clpA Escherichia coli O157:H7 str. EC4115 ATP-dependent Clp protease ATP-binding subunit YP_002269556.1 1057695 D 444450 CDS YP_002269557.1 209397314 6972349 complement(1060658..1060876) 1 NC_011353.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1060876 infA 6972349 infA Escherichia coli O157:H7 str. EC4115 translation initiation factor IF-1 YP_002269557.1 1060658 R 444450 CDS YP_002269558.1 209399489 6968276 complement(1061161..1061865) 1 NC_011353.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1061865 aat 6968276 aat Escherichia coli O157:H7 str. EC4115 leucyl/phenylalanyl-tRNA--protein transferase YP_002269558.1 1061161 R 444450 CDS YP_002269559.1 209398825 6970623 complement(1061907..1063628) 1 NC_011353.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1063628 cydC 6970623 cydC Escherichia coli O157:H7 str. EC4115 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002269559.1 1061907 R 444450 CDS YP_002269560.1 209400891 6969908 complement(1063629..1065395) 1 NC_011353.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1065395 cydD 6969908 cydD Escherichia coli O157:H7 str. EC4115 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002269560.1 1063629 R 444450 CDS YP_002269561.1 209400308 6972125 complement(1065518..1066483) 1 NC_011353.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 1066483 trxB 6972125 trxB Escherichia coli O157:H7 str. EC4115 thioredoxin reductase YP_002269561.1 1065518 R 444450 CDS YP_002269562.1 209396383 6971503 1067028..1067522 1 NC_011353.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1067522 lrp 6971503 lrp Escherichia coli O157:H7 str. EC4115 leucine-responsive transcriptional regulator YP_002269562.1 1067028 D 444450 CDS YP_002269563.1 209396855 6967288 1067657..1071685 1 NC_011353.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 1071685 ftsK 6967288 ftsK Escherichia coli O157:H7 str. EC4115 DNA translocase FtsK YP_002269563.1 1067657 D 444450 CDS YP_002269564.1 209397900 6967789 1071840..1072451 1 NC_011353.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1072451 lolA 6967789 lolA Escherichia coli O157:H7 str. EC4115 outer-membrane lipoprotein carrier protein YP_002269564.1 1071840 D 444450 CDS YP_002269565.1 209397045 6968898 1072462..1073805 1 NC_011353.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 1073805 6968898 ECH74115_1054 Escherichia coli O157:H7 str. EC4115 recombination factor protein RarA YP_002269565.1 1072462 D 444450 CDS YP_002269566.1 209396596 6967991 1073896..1075188 1 NC_011353.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1075188 serS 6967991 serS Escherichia coli O157:H7 str. EC4115 seryl-tRNA synthetase YP_002269566.1 1073896 D 444450 CDS YP_002269567.1 209400103 6967513 1075427..1077871 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 1077871 dmsA 6967513 dmsA Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase subunit A YP_002269567.1 1075427 D 444450 CDS YP_002269568.1 209399354 6971285 1077882..1078499 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951; anaerobic dimethylsulfoxide reductase subunit B 1078499 dmsB_1 6971285 dmsB_1 Escherichia coli O157:H7 str. EC4115 anaerobic dimethylsulfoxide reductase subunit B YP_002269568.1 1077882 D 444450 CDS YP_002269569.1 209398884 6970475 1078501..1079364 1 NC_011353.1 identified by match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 1079364 dmsC1 6970475 dmsC1 Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase subunit C YP_002269569.1 1078501 D 444450 CDS YP_002269570.1 209397831 6969973 complement(1079400..1080026) 1 NC_011353.1 identified by match to protein family HMM PF00857; isochorismatase family protein 1080026 6969973 ECH74115_1059 Escherichia coli O157:H7 str. EC4115 isochorismatase family protein YP_002269570.1 1079400 R 444450 CDS YP_002269571.1 209397770 6968822 complement(1080182..1080310) 1 NC_011353.1 identified by glimmer; hypothetical protein 1080310 6968822 ECH74115_1060 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269571.1 1080182 R 444450 CDS YP_002269572.1 209397044 6968758 1080341..1081489 1 NC_011353.1 identified by match to protein family HMM PF07690; MFS family transporter protein 1081489 6968758 ECH74115_1061 Escherichia coli O157:H7 str. EC4115 MFS family transporter protein YP_002269572.1 1080341 D 444450 CDS YP_002269573.1 209396586 6967990 1081699..1083129 1 NC_011353.1 identified by match to protein family HMM PF00324; amino acid permease family protein 1083129 6967990 ECH74115_1062 Escherichia coli O157:H7 str. EC4115 amino acid permease family protein YP_002269573.1 1081699 D 444450 CDS YP_002269574.1 209400841 6967501 complement(1083339..1084079) 1 NC_011353.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1084079 pflA 6967501 pflA Escherichia coli O157:H7 str. EC4115 pyruvate formate lyase-activating enzyme 1 YP_002269574.1 1083339 R 444450 CDS YP_002269575.1 209399377 6972072 complement(1084271..1086553) 1 NC_011353.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 1086553 pflB2 6972072 pflB2 Escherichia coli O157:H7 str. EC4115 formate acetyltransferase YP_002269575.1 1084271 R 444450 CDS YP_002269576.1 209397014 6970502 complement(1086608..1087465) 1 NC_011353.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790; formate transporter 1087465 6970502 ECH74115_1065 Escherichia coli O157:H7 str. EC4115 formate transporter YP_002269576.1 1086608 R 444450 CDS YP_002269577.1 209395737 6967958 complement(1087871..1089631) 1 NC_011353.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR00702; hypothetical protein 1089631 6967958 ECH74115_1066 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269577.1 1087871 R 444450 CDS YP_002269578.1 209400460 6966592 1089761..1090453 1 NC_011353.1 identified by match to protein family HMM PF04239; hypothetical protein 1090453 6966592 ECH74115_1067 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269578.1 1089761 D 444450 CDS YP_002269579.1 209400880 6971665 1090652..1091740 1 NC_011353.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1091740 serC 6971665 serC Escherichia coli O157:H7 str. EC4115 phosphoserine aminotransferase YP_002269579.1 1090652 D 444450 CDS YP_002269580.1 209400293 6972112 1091811..1093094 1 NC_011353.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1093094 aroA 6972112 aroA Escherichia coli O157:H7 str. EC4115 3-phosphoshikimate 1-carboxyvinyltransferase YP_002269580.1 1091811 D 444450 CDS YP_002269581.1 209399000 6971487 1093239..1094027 1 NC_011353.1 identified by match to protein family HMM PF01435; peptidase, M48B family 1094027 6971487 ECH74115_1070 Escherichia coli O157:H7 str. EC4115 peptidase, M48B family YP_002269581.1 1093239 D 444450 CDS YP_002269582.1 209398064 6970099 1094200..1094883 1 NC_011353.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1094883 cmk 6970099 cmk Escherichia coli O157:H7 str. EC4115 cytidylate kinase YP_002269582.1 1094200 D 444450 CDS YP_002269583.1 209397472 6969081 1094994..1096667 1 NC_011353.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1096667 rpsA 6969081 rpsA Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S1 YP_002269583.1 1094994 D 444450 CDS YP_002269584.1 209396562 6968443 1096827..1097111 1 NC_011353.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1097111 ihfB 6968443 ihfB Escherichia coli O157:H7 str. EC4115 integration host factor subunit beta YP_002269584.1 1096827 D 444450 CDS YP_002269585.1 209400423 6967476 1097318..1099582 1 NC_011353.1 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; hypothetical protein 1099582 6967476 ECH74115_1074 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269585.1 1097318 D 444450 CDS YP_002269586.1 209398481 6971625 1099619..1101367 1 NC_011353.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1101367 msbA 6971625 msbA Escherichia coli O157:H7 str. EC4115 lipid transporter ATP-binding protein/permease YP_002269586.1 1099619 D 444450 CDS YP_002269587.1 209399961 6969538 1101364..1102350 1 NC_011353.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1102350 lpxK 6969538 lpxK Escherichia coli O157:H7 str. EC4115 tetraacyldisaccharide 4'-kinase YP_002269587.1 1101364 D 444450 CDS YP_002269588.1 209398698 6971131 1102387..1103619 1 NC_011353.1 identified by match to protein family HMM PF06224; hypothetical protein 1103619 6971131 ECH74115_1077 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269588.1 1102387 D 444450 CDS YP_002269589.1 209399404 6969770 1103671..1103853 1 NC_011353.1 identified by match to protein family HMM PF03966; hypothetical protein 1103853 6969770 ECH74115_1078 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269589.1 1103671 D 444450 CDS YP_002269590.1 209399180 6970530 1103850..1104596 1 NC_011353.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1104596 kdsB 6970530 kdsB Escherichia coli O157:H7 str. EC4115 3-deoxy-manno-octulosonate cytidylyltransferase YP_002269590.1 1103850 D 444450 CDS YP_002269591.1 209398134 6970288 1104750..1105643 1 NC_011353.1 hypothetical protein 1105643 6970288 ECH74115_1081 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269591.1 1104750 D 444450 CDS YP_002269592.1 209397397 6969156 complement(1105620..1106399) 1 NC_011353.1 identified by match to protein family HMM PF02698; hypothetical protein 1106399 6969156 ECH74115_1080 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269592.1 1105620 R 444450 CDS YP_002269593.1 209396225 6968363 1106535..1107320 1 NC_011353.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1107320 smtA 6968363 smtA Escherichia coli O157:H7 str. EC4115 metallothionein SmtA YP_002269593.1 1106535 D 444450 CDS YP_002269594.1 209396953 6967115 1107317..1108639 1 NC_011353.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1108639 mukF 6967115 mukF Escherichia coli O157:H7 str. EC4115 condesin subunit F YP_002269594.1 1107317 D 444450 CDS YP_002269595.1 209400539 6967891 1108593..1109324 1 NC_011353.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1109324 mukE 6967891 mukE Escherichia coli O157:H7 str. EC4115 condesin subunit E YP_002269595.1 1108593 D 444450 CDS YP_002269596.1 209397222 6971746 1109324..1113784 1 NC_011353.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1113784 mukB 6971746 mukB Escherichia coli O157:H7 str. EC4115 cell division protein MukB YP_002269596.1 1109324 D 444450 CDS YP_002269597.1 209399966 6968180 1114057..1115892 1 NC_011353.1 identified by match to protein family HMM PF01471; hypothetical protein 1115892 6968180 ECH74115_1086 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269597.1 1114057 D 444450 CDS YP_002269598.1 209396717 6971137 1116073..1116621 1 NC_011353.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409; exported protein, Tat-dependent 1116621 6971137 ECH74115_1087 Escherichia coli O157:H7 str. EC4115 exported protein, Tat-dependent YP_002269598.1 1116073 D 444450 CDS YP_002269599.1 209395793 6967643 1116648..1117295 1 NC_011353.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 1117295 6967643 ECH74115_1088 Escherichia coli O157:H7 str. EC4115 metallo-beta-lactamase family protein YP_002269599.1 1116648 D 444450 CDS YP_002269600.1 209397827 6966649 complement(1117346..1118536) 1 NC_011353.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1118536 aspC 6966649 aspC Escherichia coli O157:H7 str. EC4115 aromatic amino acid aminotransferase YP_002269600.1 1117346 R 444450 CDS YP_002269601.1 209397832 6968818 complement(1118721..1119809) 1 NC_011353.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1119809 ompF 6968818 ompF Escherichia coli O157:H7 str. EC4115 outer membrane protein F YP_002269601.1 1118721 R 444450 CDS YP_002269602.1 209397026 6968823 complement(1120412..1121812) 1 NC_011353.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1121812 asnC 6968823 asnC Escherichia coli O157:H7 str. EC4115 asparaginyl-tRNA synthetase YP_002269602.1 1120412 R 444450 CDS YP_002269603.1 209400389 6967970 complement(1121981..1123183) 1 NC_011353.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1123183 pncB 6967970 pncB Escherichia coli O157:H7 str. EC4115 nicotinate phosphoribosyltransferase YP_002269603.1 1121981 R 444450 CDS YP_002269604.1 209396683 6969524 1123449..1126061 1 NC_011353.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414; aminopeptidase N 1126061 pepN 6969524 pepN Escherichia coli O157:H7 str. EC4115 aminopeptidase N YP_002269604.1 1123449 D 444450 CDS YP_002269605.1 209398867 6967604 complement(1126104..1126871) 1 NC_011353.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1126871 ssuB 6967604 ssuB Escherichia coli O157:H7 str. EC4115 aliphatic sulfonates transport ATP-binding subunit YP_002269605.1 1126104 R 444450 CDS YP_002269606.1 209400693 6969953 complement(1126868..1127659) 1 NC_011353.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 1127659 ssuC 6969953 ssuC Escherichia coli O157:H7 str. EC4115 alkanesulfonate transporter permease YP_002269606.1 1126868 R 444450 CDS YP_002269607.1 209398627 6971915 complement(1127671..1128816) 1 NC_011353.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1128816 ssuD 6971915 ssuD Escherichia coli O157:H7 str. EC4115 alkanesulfonate monooxygenase YP_002269607.1 1127671 R 444450 CDS YP_002269608.1 209396569 6969690 complement(1128813..1129772) 1 NC_011353.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1129772 6969690 ECH74115_1098 Escherichia coli O157:H7 str. EC4115 alkanesulfonate transporter substrate-binding subunit YP_002269608.1 1128813 R 444450 CDS YP_002269609.1 209399703 6967483 complement(1129765..1130340) 1 NC_011353.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; match to protein family HMM TIGR03567; NAD(P)H-dependent FMN reductase 1130340 6967483 ECH74115_1099 Escherichia coli O157:H7 str. EC4115 NAD(P)H-dependent FMN reductase YP_002269609.1 1129765 R 444450 CDS YP_002269610.1 209396269 6970853 1130696..1131235 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 1131235 6970853 ECH74115_1100 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002269610.1 1130696 D 444450 CDS YP_002269611.1 209396888 6967162 1131345..1132019 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 1132019 6967162 ECH74115_1101 Escherichia coli O157:H7 str. EC4115 periplasmic pilus chaperone family protein YP_002269611.1 1131345 D 444450 CDS YP_002269612.1 209400442 6971354 1135807..1136259 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 1136259 6971354 ECH74115_1105 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002269612.1 1135807 D 444450 CDS YP_002269613.1 209400946 6971645 1136270..1136782 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 1136782 6971645 ECH74115_1106 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002269613.1 1136270 D 444450 CDS YP_002269614.1 209397463 6966835 1137595..1138605 1 NC_011353.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1138605 pyrD 6966835 pyrD Escherichia coli O157:H7 str. EC4115 dihydroorotate dehydrogenase 2 YP_002269614.1 1137595 D 444450 CDS YP_002269615.1 209397700 6968434 1138779..1139321 1 NC_011353.1 identified by match to protein family HMM PF07126; hypothetical protein 1139321 6968434 ECH74115_1111 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269615.1 1138779 D 444450 CDS YP_002269616.1 209397096 6968684 complement(1139318..1140427) 1 NC_011353.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476; MOSC domain-containing protein 1140427 6968684 ECH74115_1110 Escherichia coli O157:H7 str. EC4115 MOSC domain-containing protein YP_002269616.1 1139318 R 444450 CDS YP_002269617.1 209398993 6968044 1140671..1142779 1 NC_011353.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1142779 rlmL 6968044 rlmL Escherichia coli O157:H7 str. EC4115 23S rRNA m(2)G2445 methyltransferase YP_002269617.1 1140671 D 444450 CDS YP_002269618.1 209399572 6970092 1142791..1144698 1 NC_011353.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1144698 uup 6970092 uup Escherichia coli O157:H7 str. EC4115 ABC transporter ATPase YP_002269618.1 1142791 D 444450 CDS YP_002269619.1 209396072 6970711 1144828..1146081 1 NC_011353.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155; paraquat-inducible protein A 1146081 pqiA 6970711 pqiA Escherichia coli O157:H7 str. EC4115 paraquat-inducible protein A YP_002269619.1 1144828 D 444450 CDS YP_002269620.1 209399494 6966951 1146086..1147726 1 NC_011353.1 identified by match to protein family HMM PF02470; paraquat-inducible protein B 1147726 pqiB 6966951 pqiB Escherichia coli O157:H7 str. EC4115 paraquat-inducible protein B YP_002269620.1 1146086 D 444450 CDS YP_002269621.1 209399733 6970628 1147723..1148286 1 NC_011353.1 identified by match to protein family HMM PF03886; lipoprotein 1148286 6970628 ECH74115_1116 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269621.1 1147723 D 444450 CDS YP_002269622.1 209396079 6970250 complement(1148779..1149297) 1 NC_011353.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1149297 fabA 6970250 fabA Escherichia coli O157:H7 str. EC4115 3-hydroxydecanoyl-ACP dehydratase YP_002269622.1 1148779 R 444450 CDS YP_002269623.1 209400849 6966958 complement(1149366..1151126) 1 NC_011353.1 identified by match to protein family HMM PF05362; peptidase S16 1151126 6966958 ECH74115_1119 Escherichia coli O157:H7 str. EC4115 peptidase S16 YP_002269623.1 1149366 R 444450 CDS YP_002269624.1 209398135 6972080 1151312..1151764 1 NC_011353.1 identified by match to protein family HMM PF06303; hypothetical protein 1151764 6972080 ECH74115_1120 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269624.1 1151312 D 444450 CDS YP_002269625.1 209397392 6969157 complement(1151839..1152903) 1 NC_011353.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1152903 ompA 6969157 ompA Escherichia coli O157:H7 str. EC4115 outer membrane protein A YP_002269625.1 1151839 R 444450 CDS YP_002269626.1 209399384 6968358 complement(1153236..1153745) 1 NC_011353.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623; SOS cell division inhibitor 1153745 6968358 ECH74115_1122 Escherichia coli O157:H7 str. EC4115 SOS cell division inhibitor YP_002269626.1 1153236 R 444450 CDS YP_002269627.1 209399493 6970509 1153964..1154593 1 NC_011353.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994; TfoX family protein 1154593 6970509 ECH74115_1124 Escherichia coli O157:H7 str. EC4115 TfoX family protein YP_002269627.1 1153964 D 444450 CDS YP_002269628.1 209398790 6970627 complement(1154556..1156718) 1 NC_011353.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667; hypothetical protein 1156718 6970627 ECH74115_1123 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269628.1 1154556 R 444450 CDS YP_002269629.1 209400214 6969868 complement(1156728..1157174) 1 NC_011353.1 identified by match to protein family HMM PF03733; hypothetical protein 1157174 6969868 ECH74115_1125 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269629.1 1156728 R 444450 CDS YP_002269630.1 209400242 6971402 1157297..1159351 1 NC_011353.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1159351 helD 6971402 helD Escherichia coli O157:H7 str. EC4115 DNA helicase IV YP_002269630.1 1157297 D 444450 CDS YP_002269631.1 209395706 6971432 complement(1159383..1159841) 1 NC_011353.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1159841 mgsA 6971432 mgsA Escherichia coli O157:H7 str. EC4115 methylglyoxal synthase YP_002269631.1 1159383 R 444450 CDS YP_002269632.1 209398735 6966560 complement(1159937..1160599) 1 NC_011353.1 hypothetical protein 1160599 6966560 ECH74115_1128 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269632.1 1159937 R 444450 CDS YP_002269633.1 209399500 6969810 complement(1160639..1160797) 1 NC_011353.1 identified by glimmer; hypothetical protein 1160797 6969810 ECH74115_1129 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269633.1 1160639 R 444450 CDS YP_002269634.1 209397226 6970634 1160772..1161185 1 NC_011353.1 identified by match to protein family HMM PF02629; CoA-binding protein 1161185 6970634 ECH74115_1130 Escherichia coli O157:H7 str. EC4115 CoA-binding protein YP_002269634.1 1160772 D 444450 CDS YP_002269635.1 209398008 6968184 complement(1161230..1161547) 1 NC_011353.1 identified by match to protein family HMM PF08755; match to protein family HMM TIGR02097; heat shock protein HspQ 1161547 6968184 ECH74115_1131 Escherichia coli O157:H7 str. EC4115 heat shock protein HspQ YP_002269635.1 1161230 R 444450 CDS YP_002269636.1 209400981 6969020 complement(1161605..1162795) 1 NC_011353.1 identified by match to protein family HMM PF03602; hypothetical protein 1162795 6969020 ECH74115_1132 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269636.1 1161605 R 444450 CDS YP_002269637.1 209395781 6972223 1162890..1163168 1 NC_011353.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1163168 6972223 ECH74115_1134 Escherichia coli O157:H7 str. EC4115 acylphosphatase YP_002269637.1 1162890 D 444450 CDS YP_002269638.1 209400278 6966637 complement(1163165..1163494) 1 NC_011353.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1163494 tusE 6966637 tusE Escherichia coli O157:H7 str. EC4115 sulfur transfer protein TusE YP_002269638.1 1163165 R 444450 CDS YP_002269639.1 209397904 6971471 complement(1163585..1164244) 1 NC_011353.1 identified by match to protein family HMM PF01027; hypothetical protein 1164244 6971471 ECH74115_1135 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269639.1 1163585 R 444450 CDS YP_002269640.1 209396684 6971180 complement(1165636..1165878) 1 NC_011353.1 hypothetical protein 1165878 6971180 ECH74115_1138 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269640.1 1165636 R 444450 CDS YP_002269641.1 209396180 6967605 complement(1165946..1168417) 1 NC_011353.1 exonuclease family protein 1168417 6967605 ECH74115_1139 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002269641.1 1165946 R 444450 CDS YP_002269642.1 209398172 6967066 complement(1168511..1168702) 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 1168702 6967066 ECH74115_1140 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269642.1 1168511 R 444450 CDS YP_002269643.1 209397413 6969197 complement(1168699..1168887) 1 NC_011353.1 identified by match to protein family HMM PF05358; DicB protein 1168887 6969197 ECH74115_1141 Escherichia coli O157:H7 str. EC4115 DicB protein YP_002269643.1 1168699 R 444450 CDS YP_002269644.1 209398461 6970311 1169461..1169646 1 NC_011353.1 hypothetical protein 1169646 6970311 ECH74115_1143 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269644.1 1169461 D 444450 CDS YP_002269645.1 209396968 6969514 complement(1169833..1170222) 1 NC_011353.1 hypothetical protein 1170222 6969514 ECH74115_1144 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269645.1 1169833 R 444450 CDS YP_002269646.1 209396145 6967907 complement(1170234..1170362) 1 NC_011353.1 hypothetical protein 1170362 6967907 ECH74115_1145 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269646.1 1170234 R 444450 CDS YP_002269647.1 209396025 6972010 complement(1171084..1171275) 1 NC_011353.1 hypothetical protein 1171275 6972010 ECH74115_1147 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269647.1 1171084 R 444450 CDS YP_002269648.1 209399577 6966899 complement(1171303..1171551) 1 NC_011353.1 hypothetical protein 1171551 6966899 ECH74115_1148 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269648.1 1171303 R 444450 CDS YP_002269649.1 209399807 6970717 1171957..1172085 1 NC_011353.1 hypothetical protein 1172085 6970717 ECH74115_1149 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269649.1 1171957 D 444450 CDS YP_002269650.1 209397156 6970964 1172096..1172494 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 1172494 6970964 ECH74115_1150 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269650.1 1172096 D 444450 CDS YP_002269651.1 209397804 6968108 1172460..1173017 1 NC_011353.1 hypothetical protein 1173017 6968108 ECH74115_1151 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269651.1 1172460 D 444450 CDS YP_002269652.1 209395874 6968794 1173124..1174326 1 NC_011353.1 hypothetical protein 1174326 6968794 ECH74115_1152 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269652.1 1173124 D 444450 CDS YP_002269653.1 209396577 6966738 1174333..1175079 1 NC_011353.1 identified by match to protein family HMM PF01695; replication protein 1175079 6966738 ECH74115_1153 Escherichia coli O157:H7 str. EC4115 replication protein YP_002269653.1 1174333 D 444450 CDS YP_002269654.1 209396135 6967491 1175101..1175871 1 NC_011353.1 identified by match to protein family HMM PF07789; hypothetical protein 1175871 6967491 ECH74115_1154 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269654.1 1175101 D 444450 CDS YP_002269655.1 209396751 6967018 1175887..1176300 1 NC_011353.1 identified by match to protein family HMM PF06163; hypothetical protein 1176300 6967018 ECH74115_1155 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269655.1 1175887 D 444450 CDS YP_002269656.1 209396667 6967678 complement(1176652..1177425) 1 NC_011353.1 hypothetical protein 1177425 6967678 ECH74115_1156 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269656.1 1176652 R 444450 CDS YP_002269657.1 209396179 6972156 1178633..1179682 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 1179682 6972156 ECH74115_1158 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269657.1 1178633 D 444450 CDS YP_002269658.1 209400514 6967065 1179695..1180066 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1180066 6967065 ECH74115_1159 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease RusA YP_002269658.1 1179695 D 444450 CDS YP_002269659.1 209396823 6971720 1180302..1180427 1 NC_011353.1 phage antitermination Q type 1 family protein 1180427 6971720 ECH74115_1160 Escherichia coli O157:H7 str. EC4115 phage antitermination Q type 1 family protein YP_002269659.1 1180302 D 444450 CDS YP_002269660.1 209399037 6967756 1180579..1181397 1 NC_011353.1 identified by match to protein family HMM PF02517; abortive infection protein 1181397 6967756 ECH74115_1161 Escherichia coli O157:H7 str. EC4115 abortive infection protein YP_002269660.1 1180579 D 444450 CDS YP_002269661.1 209398458 6971123 complement(1181987..1182127) 1 NC_011353.1 identified by glimmer; hypothetical protein 1182127 6971123 ECH74115_1163 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269661.1 1181987 R 444450 CDS YP_002269662.1 209399020 6969511 1182144..1182731 1 NC_011353.1 identified by match to protein family HMM PF00165; envelope protein encoded within prophage CP-933N 1182731 6969511 ECH74115_1164 Escherichia coli O157:H7 str. EC4115 envelope protein encoded within prophage CP-933N YP_002269662.1 1182144 D 444450 CDS YP_002269663.1 209399945 6972429 1183499..1185349 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 1185349 6972429 ECH74115_1168 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269663.1 1183499 D 444450 CDS YP_002269664.1 209400325 6971113 1185525..1185851 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 1185851 6971113 ECH74115_1169 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002269664.1 1185525 D 444450 CDS YP_002269665.1 209398429 6971521 1185848..1186738 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1186738 6971521 ECH74115_1170 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002269665.1 1185848 D 444450 CDS YP_002269666.1 209398859 6969477 complement(1187500..1187640) 1 NC_011353.1 hypothetical protein 1187640 6969477 ECH74115_1171 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269666.1 1187500 R 444450 CDS YP_002269667.1 209397650 6969944 complement(1187723..1188190) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 1188190 6969944 ECH74115_1172 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002269667.1 1187723 R 444450 CDS YP_002269668.1 209398280 6968633 complement(1188192..1188305) 1 NC_011353.1 identified by glimmer; hypothetical protein 1188305 6968633 ECH74115_1173 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269668.1 1188192 R 444450 CDS YP_002269669.1 209396035 6969313 complement(1188526..1189059) 1 NC_011353.1 identified by match to protein family HMM PF00959; lysozyme 1189059 6969313 ECH74115_1174 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002269669.1 1188526 R 444450 CDS YP_002269670.1 209396594 6966911 1189177..1189491 1 NC_011353.1 hypothetical protein 1189491 6966911 ECH74115_1175 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269670.1 1189177 D 444450 CDS YP_002269671.1 209399067 6967511 complement(1189747..1189911) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 1189911 6967511 ECH74115_1176 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269671.1 1189747 R 444450 CDS YP_002269672.1 209399813 6970169 1189981..1190307 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 1190307 6970169 ECH74115_1177 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002269672.1 1189981 D 444450 CDS YP_002269673.1 209399501 6970970 1190304..1191194 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1191194 6970970 ECH74115_1178 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002269673.1 1190304 D 444450 CDS YP_002269674.1 209400582 6970635 1191274..1191435 1 NC_011353.1 hypothetical protein 1191435 6970635 ECH74115_1179 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269674.1 1191274 D 444450 CDS YP_002269675.1 209398932 6971793 1192017..1192292 1 NC_011353.1 hypothetical protein 1192292 6971793 ECH74115_1180 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269675.1 1192017 D 444450 CDS YP_002269676.1 209399543 6970026 1192587..1192748 1 NC_011353.1 IS66 family element, orf1 1192748 6970026 ECH74115_1181 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf1 YP_002269676.1 1192587 D 444450 CDS YP_002269677.1 209396391 6970679 1192745..1193092 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 1193092 6970679 ECH74115_1182 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002269677.1 1192745 D 444450 CDS YP_002269678.1 209397322 6967297 1193142..1194680 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 1194680 6967297 ECH74115_1183 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002269678.1 1193142 D 444450 CDS YP_002269679.1 209400106 6968284 1194730..1194972 1 NC_011353.1 DNA packaging Nu1 1194972 6968284 ECH74115_1184 Escherichia coli O157:H7 str. EC4115 DNA packaging Nu1 YP_002269679.1 1194730 D 444450 CDS YP_002269680.1 209400197 6970606 1196857..1197063 1 NC_011353.1 identified by match to protein family HMM PF02831; gpW 1197063 6970606 ECH74115_1187 Escherichia coli O157:H7 str. EC4115 gpW YP_002269680.1 1196857 D 444450 CDS YP_002269681.1 209398854 6971384 1197060..1198652 1 NC_011353.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1198652 6971384 ECH74115_1188 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002269681.1 1197060 D 444450 CDS YP_002269682.1 209398436 6969939 1198642..1200147 1 NC_011353.1 identified by match to protein family HMM PF01343; head-tail preconnector protein GP5 1200147 6969939 ECH74115_1189 Escherichia coli O157:H7 str. EC4115 head-tail preconnector protein GP5 YP_002269682.1 1198642 D 444450 CDS YP_002269683.1 209396350 6969488 1200184..1200531 1 NC_011353.1 identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1200531 6969488 ECH74115_1190 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda head decoration protein D YP_002269683.1 1200184 D 444450 CDS YP_002269684.1 209397310 6967252 1200589..1200855 1 NC_011353.1 major head protein 1200855 6967252 ECH74115_1191 Escherichia coli O157:H7 str. EC4115 major head protein YP_002269684.1 1200589 D 444450 CDS YP_002269685.1 209396013 6968272 1200915..1201577 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 1201577 6968272 ECH74115_1192 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002269685.1 1200915 D 444450 CDS YP_002269686.1 209396757 6966886 1201591..1202022 1 NC_011353.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 1202022 6966886 ECH74115_1193 Escherichia coli O157:H7 str. EC4115 phage minor tail protein G YP_002269686.1 1201591 D 444450 CDS YP_002269687.1 209400048 6967684 1202073..1202462 1 NC_011353.1 identified by match to protein family HMM TIGR01715; phage tail assembly protein T 1202462 6967684 ECH74115_1194 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002269687.1 1202073 D 444450 CDS YP_002269688.1 209400793 6971225 1202443..1205022 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1205022 6971225 ECH74115_1195 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002269688.1 1202443 D 444450 CDS YP_002269689.1 209397157 6972019 1205019..1205348 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 1205348 6972019 ECH74115_1196 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002269689.1 1205019 D 444450 CDS YP_002269690.1 209398895 6968109 1205348..1206046 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1206046 6968109 ECH74115_1197 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002269690.1 1205348 D 444450 CDS YP_002269691.1 209397054 6969984 1206165..1206800 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 1206800 6969984 ECH74115_1198 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002269691.1 1206165 D 444450 CDS YP_002269692.1 209399647 6968000 1206797..1207378 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1207378 6968000 ECH74115_1199 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002269692.1 1206797 D 444450 CDS YP_002269693.1 209395968 6970792 complement(1207569..1208228) 1 NC_011353.1 identified by match to protein family HMM PF00080; superoxide dismutase 1208228 6970792 ECH74115_1200 Escherichia coli O157:H7 str. EC4115 superoxide dismutase YP_002269693.1 1207569 R 444450 CDS YP_002269694.1 209397821 6966837 1208230..1211703 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 1211703 6966837 ECH74115_1201 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269694.1 1208230 D 444450 CDS YP_002269695.1 209398994 6968812 1211771..1212370 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 1212370 6968812 ECH74115_1202 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002269695.1 1211771 D 444450 CDS YP_002269696.1 209400674 6970093 1212392..1213747 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 1213747 6970093 ECH74115_1203 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002269696.1 1212392 D 444450 CDS YP_002269697.1 209397139 6971893 1213749..1214018 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 1214018 6971893 ECH74115_1204 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002269697.1 1213749 D 444450 CDS YP_002269698.1 209397207 6968975 1216292..1217410 1 NC_011353.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; nickel-dependent hydrogenase 1, small subunit 1217410 hyaA 6968975 hyaA Escherichia coli O157:H7 str. EC4115 nickel-dependent hydrogenase 1, small subunit YP_002269698.1 1216292 D 444450 CDS YP_002269699.1 209400020 6968164 1217407..1219200 1 NC_011353.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1219200 hyaB 6968164 hyaB Escherichia coli O157:H7 str. EC4115 hydrogenase 1 large subunit YP_002269699.1 1217407 D 444450 CDS YP_002269700.1 209396963 6971195 1219219..1219926 1 NC_011353.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125; hydrogenase 1 b-type cytochrome subunit 1219926 hyaC 6971195 hyaC Escherichia coli O157:H7 str. EC4115 hydrogenase 1 b-type cytochrome subunit YP_002269700.1 1219219 D 444450 CDS YP_002269701.1 209398516 6967902 1219923..1220510 1 NC_011353.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1220510 hyaD 6967902 hyaD Escherichia coli O157:H7 str. EC4115 hydrogenase 1 maturation protease YP_002269701.1 1219923 D 444450 CDS YP_002269702.1 209400832 6969574 1220507..1220905 1 NC_011353.1 involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1220905 hyaE 6969574 hyaE Escherichia coli O157:H7 str. EC4115 hydrogenase-1 operon protein HyaE YP_002269702.1 1220507 D 444450 CDS YP_002269703.1 209396992 6972060 1220902..1221759 1 NC_011353.1 identified by match to protein family HMM PF04809; hydrogenase-1 operon protein HyaF 1221759 hyaF 6972060 hyaF Escherichia coli O157:H7 str. EC4115 hydrogenase-1 operon protein HyaF YP_002269703.1 1220902 D 444450 CDS YP_002269704.1 209399125 6967934 1221893..1223437 1 NC_011353.1 identified by match to protein family HMM PF01654; cytochrome bd-II oxidase subunit I 1223437 appC 6967934 appC Escherichia coli O157:H7 str. EC4115 cytochrome bd-II oxidase subunit I YP_002269704.1 1221893 D 444450 CDS YP_002269705.1 209398204 6970227 1223449..1224585 1 NC_011353.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome bd-II oxidase subunit II 1224585 appB 6970227 appB Escherichia coli O157:H7 str. EC4115 cytochrome bd-II oxidase subunit II YP_002269705.1 1223449 D 444450 CDS YP_002269706.1 209397629 6969232 1224770..1226074 1 NC_011353.1 identified by match to protein family HMM PF00328; phosphoanhydride phosphorylase 1226074 appA 6969232 appA Escherichia coli O157:H7 str. EC4115 phosphoanhydride phosphorylase YP_002269706.1 1224770 D 444450 CDS YP_002269707.1 209400850 6968611 complement(1226194..1228374) 1 NC_011353.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01007; cryptic autophosphorylating protein tyrosine kinase Etk 1228374 etk1 6968611 etk1 Escherichia coli O157:H7 str. EC4115 cryptic autophosphorylating protein tyrosine kinase Etk YP_002269707.1 1226194 R 444450 CDS YP_002269708.1 209400259 6972081 complement(1228394..1228840) 1 NC_011353.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 1228840 etp 6972081 etp Escherichia coli O157:H7 str. EC4115 phosphotyrosine-protein phosphatase YP_002269708.1 1228394 R 444450 CDS YP_002269709.1 209398304 6971451 complement(1228828..1229967) 1 NC_011353.1 identified by match to protein family HMM PF02563; outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide 1229967 yccZ 6971451 yccZ Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide YP_002269709.1 1228828 R 444450 CDS YP_002269710.1 209395798 6969340 complement(1230013..1232109) 1 NC_011353.1 identified by match to protein family HMM PF06082; group 4 capsule (G4C) polysaccharide, lipoprotein YmcA 1232109 ymcA 6969340 ymcA Escherichia coli O157:H7 str. EC4115 group 4 capsule (G4C) polysaccharide, lipoprotein YmcA YP_002269710.1 1230013 R 444450 CDS YP_002269711.1 209396475 6966654 complement(1232109..1232855) 1 NC_011353.1 identified by match to protein family HMM PF06251; group 4 capsule (G4C) polysaccharide, YmcB 1232855 ymcB 6966654 ymcB Escherichia coli O157:H7 str. EC4115 group 4 capsule (G4C) polysaccharide, YmcB YP_002269711.1 1232109 R 444450 CDS YP_002269712.1 209399944 6967386 complement(1232852..1233496) 1 NC_011353.1 group 4 capsule (G4C) polysaccharide, lipoprotein YmcC 1233496 ymcC 6967386 ymcC Escherichia coli O157:H7 str. EC4115 group 4 capsule (G4C) polysaccharide, lipoprotein YmcC YP_002269712.1 1232852 R 444450 CDS YP_002269713.1 209400547 6971112 complement(1233603..1233908) 1 NC_011353.1 inner membrane protein 1233908 6971112 ECH74115_1223 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002269713.1 1233603 R 444450 CDS YP_002269714.1 209400788 6971756 complement(1234350..1234562) 1 NC_011353.1 identified by match to protein family HMM PF00313; cold shock DNA-binding protein 1234562 6971756 ECH74115_1224 Escherichia coli O157:H7 str. EC4115 cold shock DNA-binding protein YP_002269714.1 1234350 R 444450 CDS YP_002269715.1 209398274 6972014 1234848..1235060 1 NC_011353.1 identified by match to protein family HMM PF00313; cold shock protein CspG 1235060 6972014 ECH74115_1225 Escherichia coli O157:H7 str. EC4115 cold shock protein CspG YP_002269715.1 1234848 D 444450 CDS YP_002269716.1 209396052 6969306 1235140..1235259 1 NC_011353.1 identified by glimmer; hypothetical protein 1235259 6969306 ECH74115_1226 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269716.1 1235140 D 444450 CDS YP_002269717.1 209396768 6966929 complement(1235432..1235638) 1 NC_011353.1 hypothetical protein 1235638 6966929 ECH74115_1227 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269717.1 1235432 R 444450 CDS YP_002269718.1 209400665 6967697 complement(1235675..1236748) 1 NC_011353.1 identified by match to protein family HMM PF00037; 4Fe-4S binding protein 1236748 6967697 ECH74115_1228 Escherichia coli O157:H7 str. EC4115 4Fe-4S binding protein YP_002269718.1 1235675 R 444450 CDS YP_002269719.1 209396858 6971882 complement(1236820..1239534) 1 NC_011353.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1239534 torS 6971882 torS Escherichia coli O157:H7 str. EC4115 hybrid sensory histidine kinase TorS YP_002269719.1 1236820 R 444450 CDS YP_002269720.1 209395858 6967793 1239647..1240675 1 NC_011353.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1240675 torT 6967793 torT Escherichia coli O157:H7 str. EC4115 TMAO reductase system periplasmic protein TorT YP_002269720.1 1239647 D 444450 CDS YP_002269721.1 209396267 6966717 complement(1240648..1241340) 1 NC_011353.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1241340 torR 6966717 torR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator TorR YP_002269721.1 1240648 R 444450 CDS YP_002269722.1 209400451 6967160 1241470..1242642 1 NC_011353.1 identified by match to protein family HMM PF03264; match to protein family HMM TIGR02162; cytochrome c-type protein torC 1242642 torC 6967160 torC Escherichia coli O157:H7 str. EC4115 cytochrome c-type protein torC YP_002269722.1 1241470 D 444450 CDS YP_002269723.1 209399846 6971656 1242642..1245188 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164; trimethylamine-N-oxide reductase 1245188 torA 6971656 torA Escherichia coli O157:H7 str. EC4115 trimethylamine-N-oxide reductase YP_002269723.1 1242642 D 444450 CDS YP_002269724.1 209399417 6971003 1245185..1245784 1 NC_011353.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1245784 torD 6971003 torD Escherichia coli O157:H7 str. EC4115 chaperone protein TorD YP_002269724.1 1245185 D 444450 CDS YP_002269725.1 209398797 6970543 complement(1245938..1246243) 1 NC_011353.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1246243 cbpM 6970543 cbpM Escherichia coli O157:H7 str. EC4115 chaperone-modulator protein CbpM YP_002269725.1 1245938 R 444450 CDS YP_002269726.1 209398120 6969876 complement(1246243..1247163) 1 NC_011353.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1247163 cbpA 6969876 cbpA Escherichia coli O157:H7 str. EC4115 curved DNA-binding protein CbpA YP_002269726.1 1246243 R 444450 CDS YP_002269727.1 209396924 6968039 1248834..1248950 1 NC_011353.1 identified by glimmer; hypothetical protein 1248950 6968039 ECH74115_1239 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269727.1 1248834 D 444450 CDS YP_002269728.1 209396027 6967862 1248971..1250212 1 NC_011353.1 identified by match to protein family HMM PF00328; glucose-1-phosphatase/inositol phosphatase 1250212 agp 6967862 agp Escherichia coli O157:H7 str. EC4115 glucose-1-phosphatase/inositol phosphatase YP_002269728.1 1248971 D 444450 CDS YP_002269729.1 209397797 6966903 complement(1250250..1250477) 1 NC_011353.1 hypothetical protein 1250477 6966903 ECH74115_1241 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269729.1 1250250 R 444450 CDS YP_002269730.1 209397525 6968786 complement(1250498..1251094) 1 NC_011353.1 stationary phase that binds TrpR repressor; TrpR binding protein WrbA 1251094 wrbA 6968786 wrbA Escherichia coli O157:H7 str. EC4115 TrpR binding protein WrbA YP_002269730.1 1250498 R 444450 CDS YP_002269731.1 209396914 6968498 complement(1251656..1252984) 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03616; purine permease ycdG 1252984 6968498 ECH74115_1243 Escherichia coli O157:H7 str. EC4115 purine permease ycdG YP_002269731.1 1251656 R 444450 CDS YP_002269732.1 209397828 6967852 complement(1253005..1253499) 1 NC_011353.1 identified by match to protein family HMM PF01613; match to protein family HMM TIGR03615; flavin reductase rutF 1253499 6967852 ECH74115_1244 Escherichia coli O157:H7 str. EC4115 flavin reductase rutF YP_002269732.1 1253005 R 444450 CDS YP_002269733.1 209398101 6968819 complement(1253510..1254100) 1 NC_011353.1 identified by match to protein family HMM PF00881; hypothetical protein 1254100 6968819 ECH74115_1245 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269733.1 1253510 R 444450 CDS YP_002269734.1 209397669 6969119 complement(1254110..1254910) 1 NC_011353.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR03611; rutD protein 1254910 6969119 ECH74115_1246 Escherichia coli O157:H7 str. EC4115 rutD protein YP_002269734.1 1254110 R 444450 CDS YP_002269735.1 209400895 6969502 complement(1255269..1255964) 1 NC_011353.1 identified by match to protein family HMM PF00857; match to protein family HMM TIGR03614; isochorismatase family protein, rutB 1255964 6969502 ECH74115_1248 Escherichia coli O157:H7 str. EC4115 isochorismatase family protein, rutB YP_002269735.1 1255269 R 444450 CDS YP_002269736.1 209398634 6972129 complement(1255961..1257052) 1 NC_011353.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03612; monooxygenase rutA 1257052 6972129 ECH74115_1249 Escherichia coli O157:H7 str. EC4115 monooxygenase rutA YP_002269736.1 1255961 R 444450 CDS YP_002269737.1 209399177 6969699 1257340..1257978 1 NC_011353.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08362; match to protein family HMM TIGR03613; transcriptional regulator RutR 1257978 rutR 6969699 rutR Escherichia coli O157:H7 str. EC4115 transcriptional regulator RutR YP_002269737.1 1257340 D 444450 CDS YP_002269738.1 209398214 6970285 complement(1258018..1261980) 1 NC_011353.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1261980 putA 6970285 putA Escherichia coli O157:H7 str. EC4115 multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002269738.1 1258018 R 444450 CDS YP_002269739.1 209396363 6967057 1262403..1263911 1 NC_011353.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; sodium/proline symporter 1263911 putP 6967057 putP Escherichia coli O157:H7 str. EC4115 sodium/proline symporter YP_002269739.1 1262403 D 444450 CDS YP_002269740.1 209400551 6971508 complement(1265547..1265693) 1 NC_011353.1 identified by glimmer; hypothetical protein 1265693 6971508 ECH74115_1255 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269740.1 1265547 R 444450 CDS YP_002269741.1 209398376 6971760 1265981..1266112 1 NC_011353.1 hypothetical protein 1266112 6971760 ECH74115_1256 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269741.1 1265981 D 444450 CDS YP_002269742.1 209397510 6969419 complement(1266403..1266549) 1 NC_011353.1 hypothetical protein 1266549 6969419 ECH74115_1257 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269742.1 1266403 R 444450 CDS YP_002269743.1 209398317 6968482 1266585..1267415 1 NC_011353.1 identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145; iron permease FTR1 family protein 1267415 6968482 ECH74115_1258 Escherichia coli O157:H7 str. EC4115 iron permease FTR1 family protein YP_002269743.1 1266585 D 444450 CDS YP_002269744.1 209399390 6969355 1267473..1268600 1 NC_011353.1 identified by match to protein family HMM PF09375; hypothetical protein 1268600 6969355 ECH74115_1259 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269744.1 1267473 D 444450 CDS YP_002269745.1 209398983 6970515 1268606..1269877 1 NC_011353.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; Tat-translocated enzyme 1269877 6970515 ECH74115_1260 Escherichia coli O157:H7 str. EC4115 Tat-translocated enzyme YP_002269745.1 1268606 D 444450 CDS YP_002269746.1 209399902 6970082 complement(1269944..1270063) 1 NC_011353.1 identified by glimmer; hypothetical protein 1270063 6970082 ECH74115_1261 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269746.1 1269944 R 444450 CDS YP_002269747.1 209400137 6971065 1270221..1271285 1 NC_011353.1 identified by match to protein family HMM PF02562; hypothetical protein 1271285 phoH 6971065 phoH Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269747.1 1270221 D 444450 CDS YP_002269748.1 209396546 6971323 complement(1271335..1271748) 1 NC_011353.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1271748 pgaD 6971323 pgaD Escherichia coli O157:H7 str. EC4115 PGA biosynthesis protein YP_002269748.1 1271335 R 444450 CDS YP_002269749.1 209395977 6967460 complement(1271750..1272988) 1 NC_011353.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1272988 pgaC 6967460 pgaC Escherichia coli O157:H7 str. EC4115 N-glycosyltransferase YP_002269749.1 1271750 R 444450 CDS YP_002269750.1 209397733 6966846 complement(1273068..1275086) 1 NC_011353.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1275086 pgaB 6966846 pgaB Escherichia coli O157:H7 str. EC4115 outer membrane N-deacetylase YP_002269750.1 1273068 R 444450 CDS YP_002269751.1 209397134 6968718 complement(1275095..1277518) 1 NC_011353.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1277518 pgaA 6968718 pgaA Escherichia coli O157:H7 str. EC4115 outer membrane protein PgaA YP_002269751.1 1275095 R 444450 CDS YP_002269752.1 209400191 6968083 1278033..1279463 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1279463 6968083 ECH74115_1267 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002269752.1 1278033 D 444450 CDS YP_002269753.1 209399126 6971378 1279657..1281171 1 NC_011353.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 1281171 6971378 ECH74115_1268 Escherichia coli O157:H7 str. EC4115 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein YP_002269753.1 1279657 D 444450 CDS YP_002269754.1 209400320 6970228 complement(1281273..1281764) 1 NC_011353.1 hypothetical protein 1281764 6970228 ECH74115_1269 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269754.1 1281273 R 444450 CDS YP_002269755.1 209399424 6971516 complement(1281769..1282581) 1 NC_011353.1 identified by match to protein family HMM PF00486; transcriptional regulator 1282581 6971516 ECH74115_1270 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002269755.1 1281769 R 444450 CDS YP_002269756.1 209396374 6970552 1283269..1284051 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; 2-deoxy-D-gluconate 3-dehydrogenase 1284051 6970552 ECH74115_1271 Escherichia coli O157:H7 str. EC4115 2-deoxy-D-gluconate 3-dehydrogenase YP_002269756.1 1283269 D 444450 CDS YP_002269757.1 209395800 6967279 complement(1284197..1284886) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone 1284886 6967279 ECH74115_1272 Escherichia coli O157:H7 str. EC4115 pili assembly chaperone YP_002269757.1 1284197 R 444450 CDS YP_002269758.1 209397811 6966656 complement(1284883..1286067) 1 NC_011353.1 outer membrane protein 1286067 6966656 ECH74115_1273 Escherichia coli O157:H7 str. EC4115 outer membrane protein YP_002269758.1 1284883 R 444450 CDS YP_002269759.1 209398909 6970796 complement(1288803..1289504) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone 1289504 6970796 ECH74115_1276 Escherichia coli O157:H7 str. EC4115 pili assembly chaperone YP_002269759.1 1288803 R 444450 CDS YP_002269760.1 209395888 6970001 complement(1289590..1290150) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 1290150 6970001 ECH74115_1277 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002269760.1 1289590 R 444450 CDS YP_002269761.1 209400097 6966752 complement(1290193..1290570) 1 NC_011353.1 hypothetical protein 1290570 6966752 ECH74115_1278 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269761.1 1290193 R 444450 CDS YP_002269762.1 209396689 6971279 1291158..1291304 1 NC_011353.1 identified by glimmer; hypothetical protein 1291304 6971279 ECH74115_1279 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269762.1 1291158 D 444450 CDS YP_002269763.1 209399250 6967611 1291998..1292150 1 NC_011353.1 identified by glimmer; hypothetical protein 1292150 6967611 ECH74115_1280 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269763.1 1291998 D 444450 CDS YP_002269764.1 209399804 6970364 1292207..1296019 1 NC_011353.1 identified by match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01731; match to protein family HMM TIGR01901; hypothetical protein 1296019 6970364 ECH74115_1281 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269764.1 1292207 D 444450 CDS YP_002269765.1 209397617 6970961 1296108..1297727 1 NC_011353.1 identified by match to protein family HMM PF03865; match to protein family HMM PF08479; hemolysin activator-like protein 1297727 6970961 ECH74115_1282 Escherichia coli O157:H7 str. EC4115 hemolysin activator-like protein YP_002269765.1 1296108 D 444450 CDS YP_002269766.1 209398176 6968598 1297743..1298111 1 NC_011353.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00516; match to protein family HMM TIGR00556; holo-(acyl-carrier-protein) synthase 1298111 acpS 6968598 acpS Escherichia coli O157:H7 str. EC4115 holo-(acyl-carrier-protein) synthase YP_002269766.1 1297743 D 444450 CDS YP_002269767.1 209396825 6969202 1298131..1298886 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08659; short chain dehydrogenase/reductase family oxidoreductase 1298886 6969202 ECH74115_1284 Escherichia coli O157:H7 str. EC4115 short chain dehydrogenase/reductase family oxidoreductase YP_002269767.1 1298131 D 444450 CDS YP_002269768.1 209397474 6967758 1298890..1299438 1 NC_011353.1 identified by match to protein family HMM PF07977; hypothetical protein 1299438 6967758 ECH74115_1285 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269768.1 1298890 D 444450 CDS YP_002269769.1 209400702 6968445 1299469..1299741 1 NC_011353.1 acyl-carrier protein 1299741 6968445 ECH74115_1286 Escherichia coli O157:H7 str. EC4115 acyl-carrier protein YP_002269769.1 1299469 D 444450 CDS YP_002269770.1 209395879 6971925 1299777..1300937 1 NC_011353.1 identified by match to protein family HMM PF01571; match to protein family HMM PF08669; aminomethyltransferase 1300937 6971925 ECH74115_1287 Escherichia coli O157:H7 str. EC4115 aminomethyltransferase YP_002269770.1 1299777 D 444450 CDS YP_002269771.1 209398258 6966743 1301011..1303569 1 NC_011353.1 identified by match to protein family HMM PF00109; match to protein family HMM PF02801; beta-ketoacyl synthase domain-containing protein 1303569 6966743 ECH74115_1288 Escherichia coli O157:H7 str. EC4115 beta-ketoacyl synthase domain-containing protein YP_002269771.1 1301011 D 444450 CDS YP_002269772.1 209398173 6969290 1303574..1304797 1 NC_011353.1 identified by match to protein family HMM PF00109; match to protein family HMM PF02801; beta-ketoacyl synthase domain-containing protein 1304797 6969290 ECH74115_1289 Escherichia coli O157:H7 str. EC4115 beta-ketoacyl synthase domain-containing protein YP_002269772.1 1303574 D 444450 CDS YP_002269773.1 209399379 6969198 1304794..1305747 1 NC_011353.1 hypothetical protein 1305747 6969198 ECH74115_1290 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269773.1 1304794 D 444450 CDS YP_002269774.1 209398951 6970504 1305758..1306465 1 NC_011353.1 identified by match to protein family HMM PF00005; lipoprotein-releasing system ATP-binding protein LolD 1306465 6970504 ECH74115_1291 Escherichia coli O157:H7 str. EC4115 lipoprotein-releasing system ATP-binding protein LolD YP_002269774.1 1305758 D 444450 CDS YP_002269775.1 209400877 6970045 1306449..1307105 1 NC_011353.1 hypothetical protein 1307105 6970045 ECH74115_1292 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269775.1 1306449 D 444450 CDS YP_002269776.1 209400467 6972109 1307106..1308416 1 NC_011353.1 identified by match to protein family HMM PF02687; efflux ABC transporter permease 1308416 6972109 ECH74115_1293 Escherichia coli O157:H7 str. EC4115 efflux ABC transporter permease YP_002269776.1 1307106 D 444450 CDS YP_002269777.1 209396483 6971672 1308425..1309213 1 NC_011353.1 hypothetical protein 1309213 6971672 ECH74115_1294 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269777.1 1308425 D 444450 CDS YP_002269778.1 209395743 6967395 1309210..1310598 1 NC_011353.1 hypothetical protein 1310598 6967395 ECH74115_1295 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269778.1 1309210 D 444450 CDS YP_002269779.1 209397987 6966598 1310609..1311553 1 NC_011353.1 identified by match to protein family HMM PF00698; malonyl CoA-acyl carrier protein transacylase 1311553 fabD 6966598 fabD Escherichia coli O157:H7 str. EC4115 malonyl CoA-acyl carrier protein transacylase YP_002269779.1 1310609 D 444450 CDS YP_002269780.1 209397279 6968998 1311550..1312536 1 NC_011353.1 hypothetical protein 1312536 6968998 ECH74115_1297 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269780.1 1311550 D 444450 CDS YP_002269781.1 209398563 6968240 1312903..1314105 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase 1314105 6968240 ECH74115_1298 Escherichia coli O157:H7 str. EC4115 integrase YP_002269781.1 1312903 D 444450 CDS YP_002269782.1 209396153 6969624 complement(1314292..1316109) 1 NC_011353.1 identified by glimmer; hypothetical protein 1316109 6969624 ECH74115_1299 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269782.1 1314292 R 444450 CDS YP_002269783.1 209397653 6968040 complement(1317122..1317241) 1 NC_011353.1 identified by glimmer; hypothetical protein 1317241 6968040 ECH74115_1301 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269783.1 1317122 R 444450 CDS YP_002269784.1 209398579 6968636 1318160..1319545 1 NC_011353.1 hypothetical protein 1319545 6968636 ECH74115_1302 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269784.1 1318160 D 444450 CDS YP_002269785.1 209397837 6969640 complement(1320441..1321328) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1321328 6969640 ECH74115_1303 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002269785.1 1320441 R 444450 CDS YP_002269786.1 209396786 6968829 complement(1321328..1321654) 1 NC_011353.1 overlaps another CDS with the same product name; IS629, transposase orfA 1321654 6968829 ECH74115_1304 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002269786.1 1321328 R 444450 CDS YP_002269787.1 209400222 6967717 1321715..1322242 1 NC_011353.1 hypothetical protein 1322242 6967717 ECH74115_1305 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269787.1 1321715 D 444450 CDS YP_002269788.1 209397941 6971410 1322397..1324757 1 NC_011353.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01896; match to protein family HMM PF04851; type III restriction enzyme, res subunit family 1324757 6971410 ECH74115_1306 Escherichia coli O157:H7 str. EC4115 type III restriction enzyme, res subunit family YP_002269788.1 1322397 D 444450 CDS YP_002269789.1 209396077 6968944 complement(1324919..1325095) 1 NC_011353.1 hypothetical protein 1325095 6968944 ECH74115_1307 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269789.1 1324919 R 444450 CDS YP_002269790.1 209399108 6966956 complement(1325514..1327052) 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 1327052 6966956 ECH74115_1308 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002269790.1 1325514 R 444450 CDS YP_002269791.1 209399113 6970210 complement(1327102..1327449) 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 1327449 6970210 ECH74115_1309 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002269791.1 1327102 R 444450 CDS YP_002269792.1 209398338 6970215 complement(1327446..1327607) 1 NC_011353.1 IS66 family element, orf1 1327607 6970215 ECH74115_1310 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf1 YP_002269792.1 1327446 R 444450 CDS YP_002269793.1 209398348 6969378 complement(1327902..1328213) 1 NC_011353.1 transposase InsI for insertion sequence element IS30B/C/D 1328213 6969378 ECH74115_1311 Escherichia coli O157:H7 str. EC4115 transposase InsI for insertion sequence element IS30B/C/D YP_002269793.1 1327902 R 444450 CDS YP_002269794.1 209396712 6969388 1328353..1329171 1 NC_011353.1 identified by match to protein family HMM PF00665; ISSd1, transposase orfB 1329171 6969388 ECH74115_1312 Escherichia coli O157:H7 str. EC4115 ISSd1, transposase orfB YP_002269794.1 1328353 D 444450 CDS YP_002269795.1 209397575 6967637 1329284..1329823 1 NC_011353.1 identified by match to protein family HMM PF05818; complement resistance protein 1329823 6967637 ECH74115_1313 Escherichia coli O157:H7 str. EC4115 complement resistance protein YP_002269795.1 1329284 D 444450 CDS YP_002269796.1 209397823 6971185 1330905..1331075 1 NC_011353.1 identified by glimmer; hypothetical protein 1331075 6971185 ECH74115_1316 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269796.1 1330905 D 444450 CDS YP_002269797.1 209398907 6968814 1331122..1331481 1 NC_011353.1 identified by match to protein family HMM PF01219; diacylglycerol kinase 1331481 6968814 ECH74115_1317 Escherichia coli O157:H7 str. EC4115 diacylglycerol kinase YP_002269797.1 1331122 D 444450 CDS YP_002269798.1 209397281 6969999 complement(1331574..1333193) 1 NC_011353.1 identified by match to protein family HMM PF00884; match to protein family HMM PF08019; integral membrane protein 1333193 6969999 ECH74115_1318 Escherichia coli O157:H7 str. EC4115 integral membrane protein YP_002269798.1 1331574 R 444450 CDS YP_002269799.1 209400984 6968242 1333907..1334026 1 NC_011353.1 identified by glimmer; hypothetical protein 1334026 6968242 ECH74115_1319 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269799.1 1333907 D 444450 CDS YP_002269800.1 209398300 6968485 1334863..1335165 1 NC_011353.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1335165 ureA 6968485 ureA Escherichia coli O157:H7 str. EC4115 urease subunit gamma YP_002269800.1 1334863 D 444450 CDS YP_002269801.1 209396126 6969336 1335174..1335494 1 NC_011353.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 1335494 ureB 6969336 ureB Escherichia coli O157:H7 str. EC4115 urease subunit beta YP_002269801.1 1335174 D 444450 CDS YP_002269802.1 209396808 6967007 1335487..1337190 1 NC_011353.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1337190 ureC 6967007 ureC Escherichia coli O157:H7 str. EC4115 urease subunit alpha YP_002269802.1 1335487 D 444450 CDS YP_002269803.1 209399946 6967740 1337200..1337664 1 NC_011353.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1337664 ureE 6967740 ureE Escherichia coli O157:H7 str. EC4115 urease accessory protein UreE YP_002269803.1 1337200 D 444450 CDS YP_002269804.1 209400407 6971114 1337665..1338339 1 NC_011353.1 identified by match to protein family HMM PF01730; UreF 1338339 6971114 ECH74115_1325 Escherichia coli O157:H7 str. EC4115 UreF YP_002269804.1 1337665 D 444450 CDS YP_002269805.1 209398478 6971608 1338351..1338968 1 NC_011353.1 identified by match to protein family HMM PF02492; match to protein family HMM TIGR00101; urease accessory protein UreG 1338968 ureG 6971608 ureG Escherichia coli O157:H7 str. EC4115 urease accessory protein UreG YP_002269805.1 1338351 D 444450 CDS YP_002269806.1 209400236 6969535 complement(1339016..1339141) 1 NC_011353.1 serine proteAse eata 1339141 6969535 ECH74115_1327 Escherichia coli O157:H7 str. EC4115 serine proteAse eata YP_002269806.1 1339016 R 444450 CDS YP_002269807.1 209399414 6971426 complement(1339224..1339565) 1 NC_011353.1 identified by match to protein family HMM PF01527; transposase family protein 1339565 6971426 ECH74115_1328 Escherichia coli O157:H7 str. EC4115 transposase family protein YP_002269807.1 1339224 R 444450 CDS YP_002269808.1 209397784 6970540 complement(1339627..1339755) 1 NC_011353.1 TraT 1339755 6970540 ECH74115_1329 Escherichia coli O157:H7 str. EC4115 TraT YP_002269808.1 1339627 R 444450 CDS YP_002269809.1 209399777 6968772 1340180..1340443 1 NC_011353.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1340443 rpmE2 6968772 rpmE2 Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L31 YP_002269809.1 1340180 D 444450 CDS YP_002269810.1 209400381 6970933 1340745..1340885 1 NC_011353.1 hypothetical protein 1340885 6970933 ECH74115_1331 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269810.1 1340745 D 444450 CDS YP_002269811.1 209398632 6971581 complement(1341317..1341451) 1 NC_011353.1 identified by glimmer; hypothetical protein 1341451 6971581 ECH74115_1332 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269811.1 1341317 R 444450 CDS YP_002269812.1 209399251 6969697 complement(1341757..1342428) 1 NC_011353.1 hypothetical protein 1342428 6969697 ECH74115_1333 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269812.1 1341757 R 444450 CDS YP_002269813.1 209397483 6970365 1342833..1342967 1 NC_011353.1 identified by glimmer; hypothetical protein 1342967 6970365 ECH74115_1334 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269813.1 1342833 D 444450 CDS YP_002269814.1 209398094 6968454 complement(1343448..1343621) 1 NC_011353.1 hypothetical protein 1343621 6968454 ECH74115_1335 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269814.1 1343448 R 444450 CDS YP_002269815.1 209396197 6969112 complement(1343961..1344578) 1 NC_011353.1 ISSfl3 OrfC 1344578 6969112 ECH74115_1336 Escherichia coli O157:H7 str. EC4115 ISSfl3 OrfC YP_002269815.1 1343961 R 444450 CDS YP_002269816.1 209397093 6967084 1344829..1345191 1 NC_011353.1 identified by match to protein family HMM PF01527; transposase OrfA, ISEc8 1345191 6967084 ECH74115_1337 Escherichia coli O157:H7 str. EC4115 transposase OrfA, ISEc8 YP_002269816.1 1344829 D 444450 CDS YP_002269817.1 209398600 6968041 1345188..1345538 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 1345538 6968041 ECH74115_1338 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002269817.1 1345188 D 444450 CDS YP_002269818.1 209396105 6969663 1345569..1347182 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 1347182 6969663 ECH74115_1339 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002269818.1 1345569 D 444450 CDS YP_002269819.1 209400644 6966984 complement(1347186..1348043) 1 NC_011353.1 identified by match to protein family HMM PF03050; ISSfl3 OrfC 1348043 6966984 ECH74115_1340 Escherichia coli O157:H7 str. EC4115 ISSfl3 OrfC YP_002269819.1 1347186 R 444450 CDS YP_002269820.1 209399127 6971110 complement(1348453..1348782) 1 NC_011353.1 hypothetical protein 1348782 6971110 ECH74115_1342 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269820.1 1348453 R 444450 CDS YP_002269821.1 209400902 6970229 complement(1349043..1349510) 1 NC_011353.1 TerW protein 1349510 6970229 ECH74115_1343 Escherichia coli O157:H7 str. EC4115 TerW protein YP_002269821.1 1349043 R 444450 CDS YP_002269822.1 209397597 6972137 complement(1349528..1350736) 1 NC_011353.1 hypothetical protein 1350736 6972137 ECH74115_1344 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269822.1 1349528 R 444450 CDS YP_002269823.1 209396997 6968576 complement(1350747..1351703) 1 NC_011353.1 ATP/GTP-binding protein 1351703 6968576 ECH74115_1345 Escherichia coli O157:H7 str. EC4115 ATP/GTP-binding protein YP_002269823.1 1350747 R 444450 CDS YP_002269824.1 209396436 6967939 complement(1351703..1352782) 1 NC_011353.1 hypothetical protein 1352782 6967939 ECH74115_1346 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269824.1 1351703 R 444450 CDS YP_002269825.1 209397954 6967346 complement(1352784..1353557) 1 NC_011353.1 hypothetical protein 1353557 6967346 ECH74115_1347 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269825.1 1352784 R 444450 CDS YP_002269826.1 209399867 6968959 complement(1353550..1354692) 1 NC_011353.1 hypothetical protein 1354692 6968959 ECH74115_1348 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269826.1 1353550 R 444450 CDS YP_002269827.1 209399591 6971026 complement(1354702..1355760) 1 NC_011353.1 identified by match to protein family HMM PF02655; ATP-grasp domain-containing protein 1355760 6971026 ECH74115_1349 Escherichia coli O157:H7 str. EC4115 ATP-grasp domain-containing protein YP_002269827.1 1354702 R 444450 CDS YP_002269828.1 209397516 6970732 1356083..1356664 1 NC_011353.1 identified by match to protein family HMM PF02342; tellurium resistance protein TerZ 1356664 6970732 ECH74115_1350 Escherichia coli O157:H7 str. EC4115 tellurium resistance protein TerZ YP_002269828.1 1356083 D 444450 CDS YP_002269829.1 209398119 6968489 1356664..1357821 1 NC_011353.1 identified by match to protein family HMM PF02342; protein TerA 1357821 6968489 ECH74115_1351 Escherichia coli O157:H7 str. EC4115 protein TerA YP_002269829.1 1356664 D 444450 CDS YP_002269830.1 209396128 6969138 1357844..1358299 1 NC_011353.1 identified by match to protein family HMM PF05099; protein TerB 1358299 6969138 ECH74115_1352 Escherichia coli O157:H7 str. EC4115 protein TerB YP_002269830.1 1357844 D 444450 CDS YP_002269831.1 209397186 6967010 1358322..1359362 1 NC_011353.1 identified by match to protein family HMM PF03741; tellurium resistance protein TerC 1359362 6967010 ECH74115_1353 Escherichia coli O157:H7 str. EC4115 tellurium resistance protein TerC YP_002269831.1 1358322 D 444450 CDS YP_002269832.1 209396447 6968140 1359411..1359989 1 NC_011353.1 identified by match to protein family HMM PF02342; tellurium resistance protein TerD 1359989 6968140 ECH74115_1354 Escherichia coli O157:H7 str. EC4115 tellurium resistance protein TerD YP_002269832.1 1359411 D 444450 CDS YP_002269833.1 209397646 6967357 1360058..1360633 1 NC_011353.1 identified by match to protein family HMM PF02342; tellurite resistance 1360633 6967357 ECH74115_1355 Escherichia coli O157:H7 str. EC4115 tellurite resistance YP_002269833.1 1360058 D 444450 CDS YP_002269834.1 209400678 6968629 1361055..1361441 1 NC_011353.1 protein TerF 1361441 6968629 ECH74115_1356 Escherichia coli O157:H7 str. EC4115 protein TerF YP_002269834.1 1361055 D 444450 CDS YP_002269835.1 209396334 6971897 complement(1361955..1364045) 1 NC_011353.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein 1364045 6971897 ECH74115_1357 Escherichia coli O157:H7 str. EC4115 bifunctional enterobactin receptor/adhesin protein YP_002269835.1 1361955 R 444450 CDS YP_002269836.1 209399865 6967232 1363984..1364166 1 NC_011353.1 identified by glimmer; hypothetical protein 1364166 6967232 ECH74115_1358 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269836.1 1363984 D 444450 CDS YP_002269837.1 209400041 6967916 complement(1366155..1366283) 1 NC_011353.1 identified by glimmer; hypothetical protein 1366283 6967916 ECH74115_1360 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269837.1 1366155 R 444450 CDS YP_002269838.1 209397332 6969903 1367392..1367511 1 NC_011353.1 identified by glimmer; hypothetical protein 1367511 6969903 ECH74115_1363 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269838.1 1367392 D 444450 CDS YP_002269839.1 209399240 6968297 complement(1367465..1367659) 1 NC_011353.1 hypothetical protein 1367659 6968297 ECH74115_1362 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269839.1 1367465 R 444450 CDS YP_002269840.1 209397945 6970351 1368138..1368251 1 NC_011353.1 hypothetical protein 1368251 6970351 ECH74115_1364 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269840.1 1368138 D 444450 CDS YP_002269841.1 209399436 6968948 complement(1368256..1368369) 1 NC_011353.1 identified by glimmer; hypothetical protein 1368369 6968948 ECH74115_1365 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269841.1 1368256 R 444450 CDS YP_002269842.1 209399614 6968114 1369743..1370867 1 NC_011353.1 identified by match to protein family HMM PF06722; glycosyl transferase family protein 1370867 6968114 ECH74115_1369 Escherichia coli O157:H7 str. EC4115 glycosyl transferase family protein YP_002269842.1 1369743 D 444450 CDS YP_002269843.1 209398725 6970758 complement(1371009..1371155) 1 NC_011353.1 MchS1 protein 1371155 6970758 ECH74115_1370 Escherichia coli O157:H7 str. EC4115 MchS1 protein YP_002269843.1 1371009 R 444450 CDS YP_002269844.1 209397459 6969798 complement(1371286..1371789) 1 NC_011353.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 1371789 6969798 ECH74115_1371 Escherichia coli O157:H7 str. EC4115 IS1, transposase orfB YP_002269844.1 1371286 R 444450 CDS YP_002269845.1 209399169 6968430 complement(1372221..1372679) 1 NC_011353.1 hypothetical protein 1372679 6968430 ECH74115_1372 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269845.1 1372221 R 444450 CDS YP_002269846.1 209395733 6970277 complement(1373362..1373478) 1 NC_011353.1 identified by glimmer; hypothetical protein 1373478 6970277 ECH74115_1373 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269846.1 1373362 R 444450 CDS YP_002269847.1 209397805 6966588 1373455..1373646 1 NC_011353.1 hypothetical protein 1373646 6966588 ECH74115_1374 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269847.1 1373455 D 444450 CDS YP_002269848.1 209397915 6968795 1373735..1374358 1 NC_011353.1 hypothetical protein 1374358 6968795 ECH74115_1375 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269848.1 1373735 D 444450 CDS YP_002269849.1 209397152 6968914 1374454..1374687 1 NC_011353.1 hypothetical protein 1374687 6968914 ECH74115_1376 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269849.1 1374454 D 444450 CDS YP_002269850.1 209396356 6968104 complement(1374740..1374931) 1 NC_011353.1 hypothetical protein 1374931 6968104 ECH74115_1377 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269850.1 1374740 R 444450 CDS YP_002269851.1 209396934 6967258 1375159..1375281 1 NC_011353.1 identified by glimmer; hypothetical protein 1375281 6967258 ECH74115_1378 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269851.1 1375159 D 444450 CDS YP_002269852.1 209397293 6967872 complement(1375525..1376412) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1376412 6967872 ECH74115_1379 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002269852.1 1375525 R 444450 CDS YP_002269853.1 209397479 6968254 complement(1376412..1376738) 1 NC_011353.1 overlaps another CDS with the same product name; IS629, transposase orfA 1376738 6968254 ECH74115_1380 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002269853.1 1376412 R 444450 CDS YP_002269854.1 209399951 6968450 1376901..1377965 1 NC_011353.1 identified by match to protein family HMM PF08479; match to protein family HMM TIGR01731; potra domain, shlb-type family 1377965 6968450 ECH74115_1381 Escherichia coli O157:H7 str. EC4115 potra domain, shlb-type family YP_002269854.1 1376901 D 444450 CDS YP_002269855.1 209399109 6969931 complement(1381031..1381159) 1 NC_011353.1 identified by glimmer; hypothetical protein 1381159 6969931 ECH74115_1384 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269855.1 1381031 R 444450 CDS YP_002269856.1 209397402 6970211 1381387..1382619 1 NC_011353.1 identified by match to protein family HMM PF01507; IbrA 1382619 6970211 ECH74115_1385 Escherichia coli O157:H7 str. EC4115 IbrA YP_002269856.1 1381387 D 444450 CDS YP_002269857.1 209398255 6968368 1382604..1383242 1 NC_011353.1 identified by match to protein family HMM PF02195; immunoglobulin-binding regulator B-like protein 1383242 6968368 ECH74115_1386 Escherichia coli O157:H7 str. EC4115 immunoglobulin-binding regulator B-like protein YP_002269857.1 1382604 D 444450 CDS YP_002269858.1 209396558 6969287 1383321..1383590 1 NC_011353.1 identified by match to protein family HMM PF06069; LdaB 1383590 6969287 ECH74115_1387 Escherichia coli O157:H7 str. EC4115 LdaB YP_002269858.1 1383321 D 444450 CDS YP_002269859.1 209396785 6967472 1383614..1384255 1 NC_011353.1 hypothetical protein 1384255 6967472 ECH74115_1388 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269859.1 1383614 D 444450 CDS YP_002269860.1 209399160 6969997 complement(1384953..1385201) 1 NC_011353.1 transposase 1385201 6969997 ECH74115_1390 Escherichia coli O157:H7 str. EC4115 transposase YP_002269860.1 1384953 R 444450 CDS YP_002269861.1 209396679 6970268 1385318..1385680 1 NC_011353.1 identified by match to protein family HMM PF01527; IS66 family element, orf1 1385680 6970268 ECH74115_1391 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf1 YP_002269861.1 1385318 D 444450 CDS YP_002269862.1 209397605 6967600 complement(1385980..1386162) 1 NC_011353.1 hypothetical protein 1386162 6967600 ECH74115_1392 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269862.1 1385980 R 444450 CDS YP_002269863.1 209400007 6968585 1386492..1387364 1 NC_011353.1 identified by match to protein family HMM PF01926; GTPase 1387364 6968585 ECH74115_1393 Escherichia coli O157:H7 str. EC4115 GTPase YP_002269863.1 1386492 D 444450 CDS YP_002269864.1 209399047 6967004 1387736..1390585 1 NC_011353.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; pertactin family protein 1390585 6967004 ECH74115_1395 Escherichia coli O157:H7 str. EC4115 pertactin family protein YP_002269864.1 1387736 D 444450 CDS YP_002269865.1 209399963 6970149 1390696..1393080 1 NC_011353.1 hypothetical protein 1393080 6970149 ECH74115_1396 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269865.1 1390696 D 444450 CDS YP_002269866.1 209398180 6971133 1393077..1393982 1 NC_011353.1 hypothetical protein 1393982 6971133 ECH74115_1397 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269866.1 1393077 D 444450 CDS YP_002269867.1 209398448 6969206 1393991..1395049 1 NC_011353.1 identified by match to protein family HMM PF01734; phospholipase, patatin family 1395049 6969206 ECH74115_1398 Escherichia coli O157:H7 str. EC4115 phospholipase, patatin family YP_002269867.1 1393991 D 444450 CDS YP_002269868.1 209396029 6969500 complement(1395154..1395318) 1 NC_011353.1 hypothetical protein 1395318 6969500 ECH74115_1399 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269868.1 1395154 R 444450 CDS YP_002269869.1 209396732 6966905 1395389..1396207 1 NC_011353.1 identified by match to protein family HMM PF06067; hypothetical protein 1396207 6966905 ECH74115_1400 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269869.1 1395389 D 444450 CDS YP_002269870.1 209397636 6967658 1396298..1396783 1 NC_011353.1 identified by match to protein family HMM PF03230; antirestriction protein 1396783 6967658 ECH74115_1401 Escherichia coli O157:H7 str. EC4115 antirestriction protein YP_002269870.1 1396298 D 444450 CDS YP_002269871.1 209398241 6968619 1396799..1397275 1 NC_011353.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; DNA repair protein, RadC family 1397275 6968619 ECH74115_1402 Escherichia coli O157:H7 str. EC4115 DNA repair protein, RadC family YP_002269871.1 1396799 D 444450 CDS YP_002269872.1 209399156 6969273 1397338..1397559 1 NC_011353.1 identified by match to protein family HMM PF06174; hypothetical protein 1397559 6969273 ECH74115_1403 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269872.1 1397338 D 444450 CDS YP_002269873.1 209397266 6970263 1397559..1397672 1 NC_011353.1 hypothetical protein 1397672 6970263 ECH74115_1404 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269873.1 1397559 D 444450 CDS YP_002269874.1 209398844 6968224 1397797..1398096 1 NC_011353.1 identified by match to protein family HMM PF06154; antitoxin module of toxin-antitoxin system 1398096 6968224 ECH74115_1405 Escherichia coli O157:H7 str. EC4115 antitoxin module of toxin-antitoxin system YP_002269874.1 1397797 D 444450 CDS YP_002269875.1 209400836 6969928 1398143..1398517 1 NC_011353.1 identified by match to protein family HMM PF06755; hypothetical protein 1398517 6969928 ECH74115_1406 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269875.1 1398143 D 444450 CDS YP_002269876.1 209397374 6972067 1398514..1399005 1 NC_011353.1 hypothetical protein 1399005 6972067 ECH74115_1407 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269876.1 1398514 D 444450 CDS YP_002269877.1 209399211 6968340 1399017..1399214 1 NC_011353.1 identified by match to protein family HMM PF06117; hypothetical protein 1399214 6968340 ECH74115_1408 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269877.1 1399017 D 444450 CDS YP_002269878.1 209400417 6970320 1399299..1400141 1 NC_011353.1 hypothetical protein 1400141 6970320 ECH74115_1409 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269878.1 1399299 D 444450 CDS YP_002269879.1 209399765 6972412 1400612..1401550 1 NC_011353.1 identified by match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase family protein 1401550 6972412 ECH74115_1411 Escherichia coli O157:H7 str. EC4115 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_002269879.1 1400612 D 444450 CDS YP_002269880.1 209399197 6970921 1401605..1402342 1 NC_011353.1 identified by match to protein family HMM PF02811; hydrolase 1402342 6970921 ECH74115_1412 Escherichia coli O157:H7 str. EC4115 hydrolase YP_002269880.1 1401605 D 444450 CDS YP_002269881.1 209398592 6970305 1402366..1402920 1 NC_011353.1 identified by match to protein family HMM PF06192; chaperone, TorD family 1402920 6970305 ECH74115_1413 Escherichia coli O157:H7 str. EC4115 chaperone, TorD family YP_002269881.1 1402366 D 444450 CDS YP_002269882.1 209397469 6969653 complement(1402937..1403059) 1 NC_011353.1 identified by glimmer; hypothetical protein 1403059 6969653 ECH74115_1414 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269882.1 1402937 R 444450 CDS YP_002269883.1 209399580 6968440 1403022..1403513 1 NC_011353.1 identified by match to protein family HMM PF06496; hypothetical protein 1403513 6968440 ECH74115_1415 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269883.1 1403022 D 444450 CDS YP_002269884.1 209396137 6970720 complement(1403577..1404410) 1 NC_011353.1 identified by match to protein family HMM PF03783; curli production assembly/transport subunit CsgG 1404410 csgG 6970720 csgG Escherichia coli O157:H7 str. EC4115 curli production assembly/transport subunit CsgG YP_002269884.1 1403577 R 444450 CDS YP_002269885.1 209398227 6967020 complement(1404437..1404853) 1 NC_011353.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1404853 csgF 6967020 csgF Escherichia coli O157:H7 str. EC4115 curli assembly protein CsgF YP_002269885.1 1404437 R 444450 CDS YP_002269886.1 209399830 6969258 complement(1404878..1405267) 1 NC_011353.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1405267 csgE 6969258 csgE Escherichia coli O157:H7 str. EC4115 curli assembly protein CsgE YP_002269886.1 1404878 R 444450 CDS YP_002269887.1 209396459 6970987 complement(1405272..1405922) 1 NC_011353.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1405922 csgD 6970987 csgD Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator CsgD YP_002269887.1 1405272 R 444450 CDS YP_002269888.1 209400435 6967370 1405905..1406036 1 NC_011353.1 identified by glimmer; hypothetical protein 1406036 6967370 ECH74115_1420 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269888.1 1405905 D 444450 CDS YP_002269889.1 209398648 6971637 1406649..1407131 1 NC_011353.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1407131 csgB 6971637 csgB Escherichia coli O157:H7 str. EC4115 curlin minor subunit YP_002269889.1 1406649 D 444450 CDS YP_002269890.1 209399619 6969716 1407172..1407630 1 NC_011353.1 identified by match to protein family HMM PF07012; cryptic curlin major subunit 1407630 csgA 6969716 csgA Escherichia coli O157:H7 str. EC4115 cryptic curlin major subunit YP_002269890.1 1407172 D 444450 CDS YP_002269891.1 209397004 6970763 1407689..1408021 1 NC_011353.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1408021 csgC 6970763 csgC Escherichia coli O157:H7 str. EC4115 autoagglutination protein YP_002269891.1 1407689 D 444450 CDS YP_002269892.1 209398141 6967946 1408142..1408453 1 NC_011353.1 hypothetical protein 1408453 6967946 ECH74115_1424 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269892.1 1408142 D 444450 CDS YP_002269893.1 209396250 6969163 1408548..1409081 1 NC_011353.1 identified by match to protein family HMM PF01661; hypothetical protein 1409081 6969163 ECH74115_1425 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269893.1 1408548 D 444450 CDS YP_002269894.1 209399856 6967143 1409083..1410504 1 NC_011353.1 identified by match to protein family HMM PF00614; phopholipase D 1410504 6967143 ECH74115_1426 Escherichia coli O157:H7 str. EC4115 phopholipase D YP_002269894.1 1409083 D 444450 CDS YP_002269895.1 209400526 6971015 complement(1410512..1411669) 1 NC_011353.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1411669 mdoC 6971015 mdoC Escherichia coli O157:H7 str. EC4115 glucans biosynthesis protein YP_002269895.1 1410512 R 444450 CDS YP_002269896.1 209398428 6971733 1412044..1413597 1 NC_011353.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1413597 mdoG 6971733 mdoG Escherichia coli O157:H7 str. EC4115 glucan biosynthesis protein G YP_002269896.1 1412044 D 444450 CDS YP_002269897.1 209399078 6969476 1413620..1416133 1 NC_011353.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1416133 mdoH 6969476 mdoH Escherichia coli O157:H7 str. EC4115 glucosyltransferase MdoH YP_002269897.1 1413620 D 444450 CDS YP_002269898.1 209400634 6970180 1416306..1416533 1 NC_011353.1 identified by match to protein family HMM PF07119; hypothetical protein 1416533 6970180 ECH74115_1430 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269898.1 1416306 D 444450 CDS YP_002269899.1 209399906 6971848 complement(1416534..1416908) 1 NC_011353.1 hypothetical protein 1416908 msyB 6971848 msyB Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269899.1 1416534 R 444450 CDS YP_002269900.1 209397977 6966943 complement(1418389..1419309) 1 NC_011353.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1419309 lpxL 6966943 lpxL Escherichia coli O157:H7 str. EC4115 lipid A biosynthesis lauroyl acyltransferase YP_002269900.1 1418389 R 444450 CDS YP_002269901.1 209397534 6968986 1419534..1420586 1 NC_011353.1 identified by match to protein family HMM PF00581; hypothetical protein 1420586 6968986 ECH74115_1434 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269901.1 1419534 D 444450 CDS YP_002269902.1 209399508 6968507 complement(1420628..1421203) 1 NC_011353.1 identified by match to protein family HMM PF04264; hypothetical protein 1421203 yceI 6968507 yceI Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269902.1 1420628 R 444450 CDS YP_002269903.1 209398357 6970643 complement(1421207..1421773) 1 NC_011353.1 identified by match to protein family HMM PF01292; nickel-dependent hydrogenase b-type cytochrome subunit 1421773 6970643 ECH74115_1436 Escherichia coli O157:H7 str. EC4115 nickel-dependent hydrogenase b-type cytochrome subunit YP_002269903.1 1421207 R 444450 CDS YP_002269904.1 209400448 6969398 complement(1422034..1422147) 1 NC_011353.1 hypothetical protein 1422147 6969398 ECH74115_1437 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269904.1 1422034 R 444450 CDS YP_002269905.1 209396898 6971653 complement(1422195..1423313) 1 NC_011353.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1423313 solA 6971653 solA Escherichia coli O157:H7 str. EC4115 N-methyltryptophan oxidase YP_002269905.1 1422195 R 444450 CDS YP_002269906.1 209396338 6967836 complement(1423428..1423685) 1 NC_011353.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1423685 bssS 6967836 bssS Escherichia coli O157:H7 str. EC4115 biofilm formation regulatory protein BssS YP_002269906.1 1423428 R 444450 CDS YP_002269907.1 209398168 6967237 complement(1423972..1424217) 1 NC_011353.1 identified by match to protein family HMM PF06183; DNA damage-inducible protein I 1424217 dinI 6967237 dinI Escherichia coli O157:H7 str. EC4115 DNA damage-inducible protein I YP_002269907.1 1423972 R 444450 CDS YP_002269908.1 209397912 6969193 complement(1424291..1425337) 1 NC_011353.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1425337 pyrC 6969193 pyrC Escherichia coli O157:H7 str. EC4115 dihydroorotase YP_002269908.1 1424291 R 444450 CDS YP_002269909.1 209399252 6968911 complement(1425443..1426003) 1 NC_011353.1 identified by match to protein family HMM PF07273; hypothetical protein 1426003 6968911 ECH74115_1442 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269909.1 1425443 R 444450 CDS YP_002269910.1 209398635 6970366 complement(1426137..1426784) 1 NC_011353.1 cofactor involved in the reduction of disulfides; glutaredoxin 1426784 grxB 6970366 grxB Escherichia coli O157:H7 str. EC4115 glutaredoxin YP_002269910.1 1426137 R 444450 CDS YP_002269911.1 209400380 6969700 complement(1426848..1428056) 1 NC_011353.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1428056 mdtH 6969700 mdtH Escherichia coli O157:H7 str. EC4115 multidrug resistance protein MdtH YP_002269911.1 1426848 R 444450 CDS YP_002269912.1 209399741 6971580 1428292..1428876 1 NC_011353.1 identified by match to protein family HMM PF00583; ribosomal-protein-S5-alanine N-acetyltransferase 1428876 rimJ 6971580 rimJ Escherichia coli O157:H7 str. EC4115 ribosomal-protein-S5-alanine N-acetyltransferase YP_002269912.1 1428292 D 444450 CDS YP_002269913.1 209396463 6970896 1428887..1429534 1 NC_011353.1 identified by match to protein family HMM PF04337; hypothetical protein 1429534 6970896 ECH74115_1446 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269913.1 1428887 D 444450 CDS YP_002269914.1 209396311 6967374 1429536..1430459 1 NC_011353.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase family, NAD-binding 1430459 6967374 ECH74115_1447 Escherichia coli O157:H7 str. EC4115 oxidoreductase family, NAD-binding YP_002269914.1 1429536 D 444450 CDS YP_002269915.1 209397958 6967207 1430569..1432104 1 NC_011353.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695; integral membrane protein MviN 1432104 mviN 6967207 mviN Escherichia coli O157:H7 str. EC4115 integral membrane protein MviN YP_002269915.1 1430569 D 444450 CDS YP_002269916.1 209397144 6968963 complement(1432144..1432560) 1 NC_011353.1 identified by match to protein family HMM PF05130; flagella synthesis protein FlgN 1432560 flgN 6968963 flgN Escherichia coli O157:H7 str. EC4115 flagella synthesis protein FlgN YP_002269916.1 1432144 R 444450 CDS YP_002269917.1 209399485 6968096 complement(1432565..1432858) 1 NC_011353.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1432858 flgM 6968096 flgM Escherichia coli O157:H7 str. EC4115 anti-sigma-28 factor FlgM YP_002269917.1 1432565 R 444450 CDS YP_002269918.1 209398728 6970619 complement(1432934..1433593) 1 NC_011353.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1433593 flgA 6970619 flgA Escherichia coli O157:H7 str. EC4115 flagellar basal body P-ring biosynthesis protein FlgA YP_002269918.1 1432934 R 444450 CDS YP_002269919.1 209398681 6969802 1433748..1434164 1 NC_011353.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1434164 flgB 6969802 flgB Escherichia coli O157:H7 str. EC4115 flagellar basal body rod protein FlgB YP_002269919.1 1433748 D 444450 CDS YP_002269920.1 209400948 6969751 1434168..1434572 1 NC_011353.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1434572 flgC 6969751 flgC Escherichia coli O157:H7 str. EC4115 flagellar basal body rod protein FlgC YP_002269920.1 1434168 D 444450 CDS YP_002269921.1 209396598 6972186 1434584..1435279 1 NC_011353.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1435279 flgD 6972186 flgD Escherichia coli O157:H7 str. EC4115 flagellar basal body rod modification protein YP_002269921.1 1434584 D 444450 CDS YP_002269922.1 209395987 6967515 1435304..1436509 1 NC_011353.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1436509 flgE 6967515 flgE Escherichia coli O157:H7 str. EC4115 flagellar hook protein FlgE YP_002269922.1 1435304 D 444450 CDS YP_002269923.1 209397223 6966858 1436529..1437284 1 NC_011353.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1437284 flgF 6966858 flgF Escherichia coli O157:H7 str. EC4115 flagellar basal body rod protein FlgF YP_002269923.1 1436529 D 444450 CDS YP_002269924.1 209399139 6968181 1437422..1438204 1 NC_011353.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1438204 flgG 6968181 flgG Escherichia coli O157:H7 str. EC4115 flagellar basal body rod protein FlgG YP_002269924.1 1437422 D 444450 CDS YP_002269925.1 209398398 6970245 1438257..1438955 1 NC_011353.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1438955 flgH 6970245 flgH Escherichia coli O157:H7 str. EC4115 flagellar basal body L-ring protein YP_002269925.1 1438257 D 444450 CDS YP_002269926.1 209398849 6969444 1438967..1440064 1 NC_011353.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1440064 flgI 6969444 flgI Escherichia coli O157:H7 str. EC4115 flagellar basal body P-ring protein YP_002269926.1 1438967 D 444450 CDS YP_002269927.1 209396103 6969934 1440064..1441005 1 NC_011353.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1441005 flgJ 6969934 flgJ Escherichia coli O157:H7 str. EC4115 flagellar rod assembly protein/muramidase FlgJ YP_002269927.1 1440064 D 444450 CDS YP_002269928.1 209396607 6966982 1441071..1442714 1 NC_011353.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1442714 flgK 6966982 flgK Escherichia coli O157:H7 str. EC4115 flagellar hook-associated protein FlgK YP_002269928.1 1441071 D 444450 CDS YP_002269929.1 209395853 6967525 1442726..1443679 1 NC_011353.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1443679 flgL 6967525 flgL Escherichia coli O157:H7 str. EC4115 flagellar hook-associated protein FlgL YP_002269929.1 1442726 D 444450 CDS YP_002269930.1 209400957 6966711 complement(1443874..1447059) 1 NC_011353.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1447059 rne 6966711 rne Escherichia coli O157:H7 str. EC4115 ribonuclease E YP_002269930.1 1443874 R 444450 CDS YP_002269931.1 209400210 6972195 1447632..1448591 1 NC_011353.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1448591 rluC 6972195 rluC Escherichia coli O157:H7 str. EC4115 23S rRNA pseudouridylate synthase C YP_002269931.1 1447632 D 444450 CDS YP_002269932.1 209398827 6971398 complement(1448692..1449315) 1 NC_011353.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1449315 maf2 6971398 maf2 Escherichia coli O157:H7 str. EC4115 Maf-like protein YP_002269932.1 1448692 R 444450 CDS YP_002269933.1 209397993 6969254 1450047..1450220 1 NC_011353.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1450220 rpmF 6969254 rpmF Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L32 YP_002269933.1 1450047 D 444450 CDS YP_002269934.1 209397257 6969004 1450301..1451371 1 NC_011353.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1451371 plsX 6969004 plsX Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate acyltransferase PlsX YP_002269934.1 1450301 D 444450 CDS YP_002269935.1 209397637 6968215 1451439..1452392 1 NC_011353.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1452392 fabH 6968215 fabH Escherichia coli O157:H7 str. EC4115 3-oxoacyl-ACP synthase YP_002269935.1 1451439 D 444450 CDS YP_002269936.1 209398076 6968620 1452408..1453337 1 NC_011353.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 1453337 fabD 6968620 fabD Escherichia coli O157:H7 str. EC4115 malonyl CoA-acyl carrier protein transacylase YP_002269936.1 1452408 D 444450 CDS YP_002269937.1 209396713 6969093 1453350..1454084 1 NC_011353.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1454084 fabG 6969093 fabG Escherichia coli O157:H7 str. EC4115 3-ketoacyl-ACP reductase YP_002269937.1 1453350 D 444450 CDS YP_002269938.1 209397676 6967638 1454295..1454531 1 NC_011353.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1454531 acpP 6967638 acpP Escherichia coli O157:H7 str. EC4115 acyl carrier protein YP_002269938.1 1454295 D 444450 CDS YP_002269939.1 209400908 6968659 1454619..1455860 1 NC_011353.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1455860 fabF 6968659 fabF Escherichia coli O157:H7 str. EC4115 3-oxoacyl-(acyl carrier protein) synthase II YP_002269939.1 1454619 D 444450 CDS YP_002269940.1 209396492 6972144 1455980..1456789 1 NC_011353.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1456789 pabC 6972144 pabC Escherichia coli O157:H7 str. EC4115 4-amino-4-deoxychorismate lyase YP_002269940.1 1455980 D 444450 CDS YP_002269941.1 209399164 6967404 1456792..1457814 1 NC_011353.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 1457814 6967404 ECH74115_1476 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269941.1 1456792 D 444450 CDS YP_002269942.1 209400206 6970272 1457804..1458445 1 NC_011353.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1458445 tmk 6970272 tmk Escherichia coli O157:H7 str. EC4115 thymidylate kinase YP_002269942.1 1457804 D 444450 CDS YP_002269943.1 209398319 6971394 1458442..1459446 1 NC_011353.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1459446 holB 6971394 holB Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit delta' YP_002269943.1 1458442 D 444450 CDS YP_002269944.1 209398769 6969357 1459457..1460254 1 NC_011353.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; metallodependent hydrolase 1460254 6969357 ECH74115_1479 Escherichia coli O157:H7 str. EC4115 metallodependent hydrolase YP_002269944.1 1459457 D 444450 CDS YP_002269945.1 209398205 6969847 1460549..1461982 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1461982 ptsG 6969847 ptsG Escherichia coli O157:H7 str. EC4115 PTS system glucose-specific transporter subunit IIBC YP_002269945.1 1460549 D 444450 CDS YP_002269946.1 209397400 6969233 complement(1462042..1464231) 1 NC_011353.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; ferric-rhodotorulic acid outer membrane transporter 1464231 fhuE 6969233 fhuE Escherichia coli O157:H7 str. EC4115 ferric-rhodotorulic acid outer membrane transporter YP_002269946.1 1462042 R 444450 CDS YP_002269947.1 209398129 6968366 complement(1464264..1464452) 1 NC_011353.1 hypothetical protein 1464452 6968366 ECH74115_1482 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269947.1 1464264 R 444450 CDS YP_002269948.1 209398547 6969151 1464583..1464942 1 NC_011353.1 identified by match to protein family HMM PF01230; purine nucleoside phosphoramidase 1464942 hinT 6969151 hinT Escherichia coli O157:H7 str. EC4115 purine nucleoside phosphoramidase YP_002269948.1 1464583 D 444450 CDS YP_002269949.1 209399279 6969607 1464945..1465322 1 NC_011353.1 identified by match to protein family HMM PF07233; lipoprotein 1465322 6969607 ECH74115_1484 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269949.1 1464945 D 444450 CDS YP_002269950.1 209400489 6970395 1465336..1465977 1 NC_011353.1 identified by match to protein family HMM TIGR02722; lipoprotein 1465977 6970395 ECH74115_1485 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002269950.1 1465336 D 444450 CDS YP_002269951.1 209395825 6971694 1465958..1466782 1 NC_011353.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1466782 thiK 6971694 thiK Escherichia coli O157:H7 str. EC4115 thiamine kinase YP_002269951.1 1465958 D 444450 CDS YP_002269952.1 209396392 6966682 1466793..1467818 1 NC_011353.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1467818 nagZ 6966682 nagZ Escherichia coli O157:H7 str. EC4115 beta-hexosaminidase YP_002269952.1 1466793 D 444450 CDS YP_002269953.1 209396845 6967298 1467841..1468383 1 NC_011353.1 identified by match to protein family HMM PF05728; hypothetical protein 1468383 6967298 ECH74115_1488 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269953.1 1467841 D 444450 CDS YP_002269954.1 209398186 6967778 1468783..1470087 1 NC_011353.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992; NADH dehydrogenase 1470087 ndh 6967778 ndh Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase YP_002269954.1 1468783 D 444450 CDS YP_002269955.1 209398929 6969214 1470314..1470853 1 NC_011353.1 identified by match to protein family HMM PF05433; hypothetical protein 1470853 6969214 ECH74115_1490 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269955.1 1470314 D 444450 CDS YP_002269956.1 209397174 6970022 complement(1470915..1471547) 1 NC_011353.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1471547 6970022 ECH74115_1491 Escherichia coli O157:H7 str. EC4115 TetR family transcriptional regulator YP_002269956.1 1470915 R 444450 CDS YP_002269957.1 209397937 6968127 1471788..1472045 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 1472045 6968127 ECH74115_1492 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269957.1 1471788 D 444450 CDS YP_002269958.1 209398807 6968940 complement(1472128..1473087) 1 NC_011353.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM domain/ErfK/YbiS/YcfS/YnhG family protein 1473087 6968940 ECH74115_1493 Escherichia coli O157:H7 str. EC4115 LysM domain/ErfK/YbiS/YcfS/YnhG family protein YP_002269958.1 1472128 R 444450 CDS YP_002269959.1 209399391 6969887 complement(1473234..1476680) 1 NC_011353.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 1476680 mfd 6969887 mfd Escherichia coli O157:H7 str. EC4115 transcription-repair coupling factor YP_002269959.1 1473234 R 444450 CDS YP_002269960.1 209400262 6970516 complement(1476808..1477881) 1 NC_011353.1 identified by match to protein family HMM PF01757; acyltransferase 1477881 6970516 ECH74115_1495 Escherichia coli O157:H7 str. EC4115 acyltransferase YP_002269960.1 1476808 R 444450 CDS YP_002269961.1 209400879 6971455 1478143..1479342 1 NC_011353.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1479342 lolC 6971455 lolC Escherichia coli O157:H7 str. EC4115 outer membrane-specific lipoprotein transporter subunit LolC YP_002269961.1 1478143 D 444450 CDS YP_002269962.1 209395996 6972111 1479335..1480036 1 NC_011353.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1480036 lolD 6972111 lolD Escherichia coli O157:H7 str. EC4115 lipoprotein transporter ATP-binding subunit YP_002269962.1 1479335 D 444450 CDS YP_002269963.1 209397376 6966867 1480036..1481280 1 NC_011353.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1481280 lolE 6966867 lolE Escherichia coli O157:H7 str. EC4115 outer membrane-specific lipoprotein transporter subunit LolE YP_002269963.1 1480036 D 444450 CDS YP_002269964.1 209397162 6968342 1481309..1482220 1 NC_011353.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1482220 nagK 6968342 nagK Escherichia coli O157:H7 str. EC4115 N-acetyl-D-glucosamine kinase YP_002269964.1 1481309 D 444450 CDS YP_002269965.1 209397898 6968115 1482236..1483057 1 NC_011353.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1483057 npdA 6968115 npdA Escherichia coli O157:H7 str. EC4115 NAD-dependent deacetylase YP_002269965.1 1482236 D 444450 CDS YP_002269966.1 209398103 6968896 complement(1483213..1484259) 1 NC_011353.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1484259 potD 6968896 potD Escherichia coli O157:H7 str. EC4115 spermidine/putrescine ABC transporter substrate-binding protein YP_002269966.1 1483213 R 444450 CDS YP_002269967.1 209397358 6969121 complement(1484256..1485050) 1 NC_011353.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1485050 potC 6969121 potC Escherichia coli O157:H7 str. EC4115 spermidine/putrescine ABC transporter membrane protein YP_002269967.1 1484256 R 444450 CDS YP_002269968.1 209398624 6968325 complement(1485217..1486335) 1 NC_011353.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; phage integrase family protein 1486335 6968325 ECH74115_1503 Escherichia coli O157:H7 str. EC4115 phage integrase family protein YP_002269968.1 1485217 R 444450 CDS YP_002269969.1 209400557 6969687 complement(1486304..1486573) 1 NC_011353.1 excisionase 1486573 6969687 ECH74115_1504 Escherichia coli O157:H7 str. EC4115 excisionase YP_002269969.1 1486304 R 444450 CDS YP_002269970.1 209399825 6971766 complement(1486635..1486979) 1 NC_011353.1 exodeoxyribonuclease VIII 1486979 6971766 ECH74115_1505 Escherichia coli O157:H7 str. EC4115 exodeoxyribonuclease VIII YP_002269970.1 1486635 R 444450 CDS YP_002269971.1 209396932 6970982 1487157..1487672 1 NC_011353.1 hypothetical protein 1487672 6970982 ECH74115_1506 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269971.1 1487157 D 444450 CDS YP_002269972.1 209396186 6967870 complement(1487787..1488017) 1 NC_011353.1 identified by match to protein family HMM PF07151; hypothetical protein 1488017 6967870 ECH74115_1507 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269972.1 1487787 R 444450 CDS YP_002269973.1 209398181 6967072 complement(1488255..1488731) 1 NC_011353.1 Rac prophage repressor 1488731 6967072 ECH74115_1508 Escherichia coli O157:H7 str. EC4115 Rac prophage repressor YP_002269973.1 1488255 R 444450 CDS YP_002269974.1 209399310 6969207 1489163..1489588 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 1489588 6969207 ECH74115_1509 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269974.1 1489163 D 444450 CDS YP_002269975.1 209399428 6970427 1489657..1490694 1 NC_011353.1 hypothetical protein 1490694 6970427 ECH74115_1510 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269975.1 1489657 D 444450 CDS YP_002269976.1 209398263 6970556 1490726..1491148 1 NC_011353.1 hypothetical protein 1491148 6970556 ECH74115_1511 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269976.1 1490726 D 444450 CDS YP_002269977.1 209397512 6969295 1491182..1491898 1 NC_011353.1 identified by match to protein family HMM PF07789; hypothetical protein 1491898 6969295 ECH74115_1512 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269977.1 1491182 D 444450 CDS YP_002269978.1 209399420 6968484 1491958..1492212 1 NC_011353.1 hypothetical protein 1492212 6968484 ECH74115_1513 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269978.1 1491958 D 444450 CDS YP_002269979.1 209398802 6970546 1492215..1492511 1 NC_011353.1 hypothetical protein 1492511 6970546 ECH74115_1514 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269979.1 1492215 D 444450 CDS YP_002269980.1 209400886 6969881 1492501..1492818 1 NC_011353.1 hypothetical protein 1492818 6969881 ECH74115_1515 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269980.1 1492501 D 444450 CDS YP_002269981.1 209400267 6972119 1492967..1493089 1 NC_011353.1 hypothetical protein 1493089 6972119 ECH74115_1516 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269981.1 1492967 D 444450 CDS YP_002269982.1 209399674 6971460 1493076..1493513 1 NC_011353.1 hypothetical protein 1493513 6971460 ECH74115_1517 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269982.1 1493076 D 444450 CDS YP_002269983.1 209396589 6970822 1493515..1493706 1 NC_011353.1 hypothetical protein 1493706 6970822 ECH74115_1518 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269983.1 1493515 D 444450 CDS YP_002269984.1 209397375 6967504 1493709..1494296 1 NC_011353.1 identified by match to protein family HMM PF04448; hypothetical protein 1494296 6967504 ECH74115_1519 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269984.1 1493709 D 444450 CDS YP_002269985.1 209399322 6968341 1494367..1494516 1 NC_011353.1 hypothetical protein 1494516 6968341 ECH74115_1520 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269985.1 1494367 D 444450 CDS YP_002269986.1 209399131 6970888 1495365..1496414 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 1496414 6970888 ECH74115_1522 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269986.1 1495365 D 444450 CDS YP_002269987.1 209400904 6970233 1496427..1496684 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1496684 6970233 ECH74115_1523 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease RusA YP_002269987.1 1496427 D 444450 CDS YP_002269988.1 209397659 6972139 1496665..1497957 1 NC_011353.1 identified by match to protein family HMM PF03629; YjhS 1497957 6972139 ECH74115_1524 Escherichia coli O157:H7 str. EC4115 YjhS YP_002269988.1 1496665 D 444450 CDS YP_002269989.1 209399407 6968642 1498105..1498287 1 NC_011353.1 identified by match to protein family HMM PF07125; hypothetical protein 1498287 6968642 ECH74115_1525 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269989.1 1498105 D 444450 CDS YP_002269990.1 209396116 6970533 1498325..1498594 1 NC_011353.1 identified by match to protein family HMM PF05696; hypothetical protein 1498594 6970533 ECH74115_1526 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269990.1 1498325 D 444450 CDS YP_002269991.1 209397874 6966996 1498670..1498885 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 1498885 6966996 ECH74115_1527 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269991.1 1498670 D 444450 CDS YP_002269992.1 209400294 6968869 1498890..1499234 1 NC_011353.1 identified by match to protein family HMM PF07041; hypothetical protein 1499234 6968869 ECH74115_1528 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269992.1 1498890 D 444450 CDS YP_002269993.1 209396756 6971488 1499285..1499818 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 1499818 6971488 ECH74115_1529 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002269993.1 1499285 D 444450 CDS YP_002269994.1 209400643 6967683 1500089..1500658 1 NC_011353.1 anti-repressor protein Ant 1500658 6967683 ECH74115_1530 Escherichia coli O157:H7 str. EC4115 anti-repressor protein Ant YP_002269994.1 1500089 D 444450 CDS YP_002269995.1 209397245 6971857 1500658..1500804 1 NC_011353.1 hypothetical protein 1500804 6971857 ECH74115_1531 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269995.1 1500658 D 444450 CDS YP_002269996.1 209396433 6968203 1500812..1501279 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 1501279 6968203 ECH74115_1532 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002269996.1 1500812 D 444450 CDS YP_002269997.1 209395695 6967341 1501303..1501527 1 NC_011353.1 hypothetical protein 1501527 6967341 ECH74115_1533 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269997.1 1501303 D 444450 CDS YP_002269998.1 209400272 6966549 1501675..1501797 1 NC_011353.1 identified by glimmer; hypothetical protein 1501797 6966549 ECH74115_1534 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269998.1 1501675 D 444450 CDS YP_002269999.1 209396803 6971465 1501884..1502024 1 NC_011353.1 hypothetical protein 1502024 6971465 ECH74115_1535 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002269999.1 1501884 D 444450 CDS YP_002270000.1 209398723 6967735 complement(1502154..1502279) 1 NC_011353.1 hypothetical protein 1502279 6967735 ECH74115_1536 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270000.1 1502154 R 444450 CDS YP_002270001.1 209400637 6969796 1503036..1503599 1 NC_011353.1 terminase small subunit 1503599 6969796 ECH74115_1537 Escherichia coli O157:H7 str. EC4115 terminase small subunit YP_002270001.1 1503036 D 444450 CDS YP_002270002.1 209400939 6971851 1503596..1505257 1 NC_011353.1 identified by match to protein family HMM PF03354; phage terminase, large subunit 1505257 6971851 ECH74115_1538 Escherichia coli O157:H7 str. EC4115 phage terminase, large subunit YP_002270002.1 1503596 D 444450 CDS YP_002270003.1 209400333 6972176 1505321..1507258 1 NC_011353.1 identified by match to protein family HMM PF04586; prohead protease 1507258 6972176 ECH74115_1539 Escherichia coli O157:H7 str. EC4115 prohead protease YP_002270003.1 1505321 D 444450 CDS YP_002270004.1 209399454 6971530 1507470..1509971 1 NC_011353.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 1509971 6971530 ECH74115_1540 Escherichia coli O157:H7 str. EC4115 phage portal protein, HK97 family YP_002270004.1 1507470 D 444450 CDS YP_002270005.1 209399104 6967094 1510051..1510377 1 NC_011353.1 hypothetical protein 1510377 6967094 ECH74115_1542 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270005.1 1510051 D 444450 CDS YP_002270006.1 209397142 6970206 1510387..1510737 1 NC_011353.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor 1510737 6970206 ECH74115_1543 Escherichia coli O157:H7 str. EC4115 phage head-tail adaptor YP_002270006.1 1510387 D 444450 CDS YP_002270007.1 209399398 6968094 1510734..1511180 1 NC_011353.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 1511180 6968094 ECH74115_1544 Escherichia coli O157:H7 str. EC4115 phage protein, HK97 gp10 family YP_002270007.1 1510734 D 444450 CDS YP_002270008.1 209397611 6970524 1511177..1511521 1 NC_011353.1 identified by glimmer; hypothetical protein 1511521 6970524 ECH74115_1545 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270008.1 1511177 D 444450 CDS YP_002270009.1 209398942 6971650 1512318..1512692 1 NC_011353.1 identified by match to protein family HMM PF06222; phage tail assembly chaperone 1512692 6971650 ECH74115_1547 Escherichia coli O157:H7 str. EC4115 phage tail assembly chaperone YP_002270009.1 1512318 D 444450 CDS YP_002270010.1 209400217 6970036 1512794..1512997 1 NC_011353.1 identified by glimmer; hypothetical protein 1512997 6970036 ECH74115_1548 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270010.1 1512794 D 444450 CDS YP_002270011.1 209400951 6971405 1513050..1516292 1 NC_011353.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein 1516292 6971405 ECH74115_1549 Escherichia coli O157:H7 str. EC4115 tail length tape measure protein YP_002270011.1 1513050 D 444450 CDS YP_002270012.1 209397703 6972189 1516285..1516626 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 1516626 6972189 ECH74115_1550 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002270012.1 1516285 D 444450 CDS YP_002270013.1 209398837 6968687 1516626..1517324 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1517324 6968687 ECH74115_1551 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002270013.1 1516626 D 444450 CDS YP_002270014.1 209400770 6969921 complement(1517341..1517481) 1 NC_011353.1 regulatory protein 1517481 6969921 ECH74115_1552 Escherichia coli O157:H7 str. EC4115 regulatory protein YP_002270014.1 1517341 R 444450 CDS YP_002270015.1 209400306 6971995 1517675..1517815 1 NC_011353.1 hypothetical protein 1517815 6971995 ECH74115_1553 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270015.1 1517675 D 444450 CDS YP_002270016.1 209400295 6972253 1518118..1518996 1 NC_011353.1 identified by match to protein family HMM PF02498; antirepressor protein 1518996 6972253 ECH74115_1555 Escherichia coli O157:H7 str. EC4115 antirepressor protein YP_002270016.1 1518118 D 444450 CDS YP_002270017.1 209399408 6971489 1519050..1519787 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 1519787 6971489 ECH74115_1556 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002270017.1 1519050 D 444450 CDS YP_002270018.1 209396117 6970534 1519784..1519969 1 NC_011353.1 bacteriophage lambda tail assembly protein I 1519969 6970534 ECH74115_1557 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002270018.1 1519784 D 444450 CDS YP_002270019.1 209400535 6966997 1520091..1522439 1 NC_011353.1 identified by glimmer; hypothetical protein 1522439 6966997 ECH74115_1558 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270019.1 1520091 D 444450 CDS YP_002270020.1 209396457 6971742 1523030..1526431 1 NC_011353.1 identified by glimmer; hypothetical protein 1526431 6971742 ECH74115_1559 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270020.1 1523030 D 444450 CDS YP_002270021.1 209395722 6967368 complement(1526808..1526927) 1 NC_011353.1 hypothetical protein 1526927 6967368 ECH74115_1560 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270021.1 1526808 R 444450 CDS YP_002270022.1 209397975 6966577 complement(1526974..1527879) 1 NC_011353.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 1527879 6966577 ECH74115_1561 Escherichia coli O157:H7 str. EC4115 insertion element IS2 transposase InsD YP_002270022.1 1526974 R 444450 CDS YP_002270023.1 209395707 6969833 1528384..1528512 1 NC_011353.1 transposase 1528512 6969833 ECH74115_1564 Escherichia coli O157:H7 str. EC4115 transposase YP_002270023.1 1528384 D 444450 CDS YP_002270024.1 209400220 6966561 complement(1529076..1530437) 1 NC_011353.1 hypothetical protein 1530437 6966561 ECH74115_1565 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270024.1 1529076 R 444450 CDS YP_002270025.1 209400194 6971408 complement(1530801..1531664) 1 NC_011353.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1531664 potB 6971408 potB Escherichia coli O157:H7 str. EC4115 spermidine/putrescine ABC transporter membrane protein YP_002270025.1 1530801 R 444450 CDS YP_002270026.1 209400971 6971381 complement(1531648..1532784) 1 NC_011353.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1532784 potA 6971381 potA Escherichia coli O157:H7 str. EC4115 putrescine/spermidine ABC transporter ATPase YP_002270026.1 1531648 R 444450 CDS YP_002270027.1 209398016 6972211 1532992..1534260 1 NC_011353.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1534260 pepT 6972211 pepT Escherichia coli O157:H7 str. EC4115 peptidase T YP_002270027.1 1532992 D 444450 CDS YP_002270028.1 209395797 6969029 complement(1534309..1535430) 1 NC_011353.1 identified by match to protein family HMM PF08007; cupin family protein 1535430 6969029 ECH74115_1569 Escherichia coli O157:H7 str. EC4115 cupin family protein YP_002270028.1 1534309 R 444450 CDS YP_002270029.1 209397205 6966653 complement(1535510..1535674) 1 NC_011353.1 hypothetical protein 1535674 6966653 ECH74115_1570 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270029.1 1535510 R 444450 CDS YP_002270030.1 209397964 6968162 1535679..1536908 1 NC_011353.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 1536908 6968162 ECH74115_1571 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002270030.1 1535679 D 444450 CDS YP_002270031.1 209399546 6968969 1537519..1538463 1 NC_011353.1 hypothetical protein 1538463 6968969 ECH74115_1572 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270031.1 1537519 D 444450 CDS YP_002270032.1 209397613 6970683 1538456..1538668 1 NC_011353.1 identified by glimmer; hypothetical protein 1538668 6970683 ECH74115_1573 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270032.1 1538456 D 444450 CDS YP_002270033.1 209398673 6971817 1539115..1539348 1 NC_011353.1 hypothetical protein 1539348 6971817 ECH74115_1575 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270033.1 1539115 D 444450 CDS YP_002270034.1 209399060 6969743 1539354..1539653 1 NC_011353.1 hypothetical protein 1539653 6969743 ECH74115_1576 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270034.1 1539354 D 444450 CDS YP_002270035.1 209399659 6970162 1539650..1541050 1 NC_011353.1 bacteriophage P4 DNA primease 1541050 6970162 ECH74115_1577 Escherichia coli O157:H7 str. EC4115 bacteriophage P4 DNA primease YP_002270035.1 1539650 D 444450 CDS YP_002270036.1 209400605 6970806 1541251..1541502 1 NC_011353.1 bacteriophage protein 1541502 6970806 ECH74115_1578 Escherichia coli O157:H7 str. EC4115 bacteriophage protein YP_002270036.1 1541251 D 444450 CDS YP_002270037.1 209399838 6971816 1541499..1541909 1 NC_011353.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-strand binding protein 1541909 6971816 ECH74115_1579 Escherichia coli O157:H7 str. EC4115 single-strand binding protein YP_002270037.1 1541499 D 444450 CDS YP_002270038.1 209396824 6970995 1542149..1542277 1 NC_011353.1 identified by glimmer; hypothetical protein 1542277 6970995 ECH74115_1580 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270038.1 1542149 D 444450 CDS YP_002270039.1 209396288 6966894 1542795..1543001 1 NC_011353.1 hypothetical protein 1543001 6966894 ECH74115_1582 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270039.1 1542795 D 444450 CDS YP_002270040.1 209396882 6967183 1543001..1544056 1 NC_011353.1 identified by match to protein family HMM PF03864; phage major capsid protein E 1544056 6967183 ECH74115_1583 Escherichia coli O157:H7 str. EC4115 phage major capsid protein E YP_002270040.1 1543001 D 444450 CDS YP_002270041.1 209400344 6967819 1544069..1544404 1 NC_011353.1 identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1544404 6967819 ECH74115_1584 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda head decoration protein D YP_002270041.1 1544069 D 444450 CDS YP_002270042.1 209395958 6971542 1544417..1544830 1 NC_011353.1 hypothetical protein 1544830 6971542 ECH74115_1585 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270042.1 1544417 D 444450 CDS YP_002270043.1 209400158 6966825 1545051..1545578 1 NC_011353.1 identified by match to protein family HMM PF07471; gp1 1545578 6966825 ECH74115_1587 Escherichia coli O157:H7 str. EC4115 gp1 YP_002270043.1 1545051 D 444450 CDS YP_002270044.1 209399205 6971344 complement(1545558..1545782) 1 NC_011353.1 hypothetical protein 1545782 6971344 ECH74115_1586 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270044.1 1545558 R 444450 CDS YP_002270045.1 209398061 6970314 1545834..1546115 1 NC_011353.1 bacteriophage protein 1546115 6970314 ECH74115_1588 Escherichia coli O157:H7 str. EC4115 bacteriophage protein YP_002270045.1 1545834 D 444450 CDS YP_002270046.1 209397549 6970070 complement(1546716..1548176) 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918; sensor protein PhoQ 1548176 phoQ 6970070 phoQ Escherichia coli O157:H7 str. EC4115 sensor protein PhoQ YP_002270046.1 1546716 R 444450 CDS YP_002270047.1 209395806 6968523 complement(1548176..1548847) 1 NC_011353.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1548847 phoP 6968523 phoP Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator PhoP YP_002270047.1 1548176 R 444450 CDS YP_002270048.1 209399204 6966662 complement(1549016..1550386) 1 NC_011353.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1550386 purB 6966662 purB Escherichia coli O157:H7 str. EC4115 adenylosuccinate lyase YP_002270048.1 1549016 R 444450 CDS YP_002270049.1 209398608 6970313 complement(1550390..1551031) 1 NC_011353.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1551031 6970313 ECH74115_1593 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270049.1 1550390 R 444450 CDS YP_002270050.1 209397379 6969671 complement(1551067..1552173) 1 NC_011353.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1552173 mnmA 6969671 mnmA Escherichia coli O157:H7 str. EC4115 tRNA-specific 2-thiouridylase MnmA YP_002270050.1 1551067 R 444450 CDS YP_002270051.1 209399573 6968345 complement(1552227..1552688) 1 NC_011353.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 1552688 6968345 ECH74115_1595 Escherichia coli O157:H7 str. EC4115 NUDIX family hydrolase YP_002270051.1 1552227 R 444450 CDS YP_002270052.1 209396285 6970712 complement(1552698..1553321) 1 NC_011353.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1553321 rluE 6970712 rluE Escherichia coli O157:H7 str. EC4115 23S rRNA pseudouridine synthase E YP_002270052.1 1552698 R 444450 CDS YP_002270053.1 209397717 6967179 complement(1553439..1553552) 1 NC_011353.1 hypothetical protein 1553552 6967179 ECH74115_1597 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270053.1 1553439 R 444450 CDS YP_002270054.1 209399750 6968702 1553523..1554773 1 NC_011353.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1554773 icd 6968702 icd Escherichia coli O157:H7 str. EC4115 isocitrate dehydrogenase YP_002270054.1 1553523 D 444450 CDS YP_002270055.1 209396519 6970906 complement(1554887..1556029) 1 NC_011353.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; intergrase 1556029 6970906 ECH74115_1599 Escherichia coli O157:H7 str. EC4115 intergrase YP_002270055.1 1554887 R 444450 CDS YP_002270056.1 209398683 6967432 1556359..1557183 1 NC_011353.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; replication protein O 1557183 6967432 ECH74115_1600 Escherichia coli O157:H7 str. EC4115 replication protein O YP_002270056.1 1556359 D 444450 CDS YP_002270057.1 209399926 6969753 1557180..1557881 1 NC_011353.1 identified by match to protein family HMM PF06992; replication protein P 1557881 6969753 ECH74115_1601 Escherichia coli O157:H7 str. EC4115 replication protein P YP_002270057.1 1557180 D 444450 CDS YP_002270058.1 209396641 6971090 1557878..1558180 1 NC_011353.1 hypothetical protein 1558180 6971090 ECH74115_1602 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270058.1 1557878 D 444450 CDS YP_002270059.1 209397090 6967561 1558248..1558580 1 NC_011353.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 1558580 emrE 6967561 emrE Escherichia coli O157:H7 str. EC4115 multidrug efflux protein YP_002270059.1 1558248 D 444450 CDS YP_002270060.1 209397712 6972020 1560849..1561304 1 NC_011353.1 DLP12 prophage; hypothetical protein 1561304 6972020 ECH74115_1606 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270060.1 1560849 D 444450 CDS YP_002270061.1 209398953 6968696 1561304..1561474 1 NC_011353.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 1561474 6968696 ECH74115_1607 Escherichia coli O157:H7 str. EC4115 prophage protein NinE YP_002270061.1 1561304 D 444450 CDS YP_002270062.1 209396518 6970047 1561467..1561757 1 NC_011353.1 identified by match to protein family HMM PF07102; hypothetical protein 1561757 6970047 ECH74115_1608 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270062.1 1561467 D 444450 CDS YP_002270063.1 209397251 6967430 1561754..1562116 1 NC_011353.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1562116 rusA 6967430 rusA Escherichia coli O157:H7 str. EC4115 endodeoxyribonuclease RUS YP_002270063.1 1561754 D 444450 CDS YP_002270064.1 209395937 6968209 1562116..1562253 1 NC_011353.1 hypothetical protein 1562253 6968209 ECH74115_1610 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270064.1 1562116 D 444450 CDS YP_002270065.1 209396649 6966804 1562250..1562939 1 NC_011353.1 identified by match to protein family HMM PF06323; antitermination protein 1562939 6966804 ECH74115_1611 Escherichia coli O157:H7 str. EC4115 antitermination protein YP_002270065.1 1562250 D 444450 CDS YP_002270066.1 209399475 6967569 1563249..1563566 1 NC_011353.1 gp13 1563566 6967569 ECH74115_1612 Escherichia coli O157:H7 str. EC4115 gp13 YP_002270066.1 1563249 D 444450 CDS YP_002270067.1 209397363 6970608 1563553..1564029 1 NC_011353.1 identified by match to protein family HMM PF00959; lysozyme 1564029 6970608 ECH74115_1613 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002270067.1 1563553 D 444450 CDS YP_002270068.1 209400367 6968330 1564026..1564487 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 1564487 6968330 ECH74115_1614 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002270068.1 1564026 D 444450 CDS YP_002270069.1 209398869 6971565 complement(1564519..1564812) 1 NC_011353.1 identified by match to protein family HMM PF06291; Bor 1564812 6971565 ECH74115_1615 Escherichia coli O157:H7 str. EC4115 Bor YP_002270069.1 1564519 R 444450 CDS YP_002270070.1 209398335 6969955 complement(1565104..1565514) 1 NC_011353.1 identified by match to protein family HMM PF07166; hypothetical protein 1565514 6969955 ECH74115_1616 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270070.1 1565104 R 444450 CDS YP_002270071.1 209395761 6969375 1565800..1566006 1 NC_011353.1 hypothetical protein 1566006 6969375 ECH74115_1617 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270071.1 1565800 D 444450 CDS YP_002270072.1 209399036 6966616 complement(1566171..1566305) 1 NC_011353.1 hypothetical protein 1566305 6966616 ECH74115_1618 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270072.1 1566171 R 444450 CDS YP_002270073.1 209397590 6970137 1566754..1567299 1 NC_011353.1 identified by match to protein family HMM PF07471; phage DNA packaging protein Nu1 1567299 6970137 ECH74115_1619 Escherichia coli O157:H7 str. EC4115 phage DNA packaging protein Nu1 YP_002270073.1 1566754 D 444450 CDS YP_002270074.1 209398443 6968568 1567274..1569199 1 NC_011353.1 identified by match to protein family HMM PF05876; phage terminase large subunit 1569199 6968568 ECH74115_1620 Escherichia coli O157:H7 str. EC4115 phage terminase large subunit YP_002270074.1 1567274 D 444450 CDS YP_002270075.1 209399044 6969495 1569196..1569402 1 NC_011353.1 identified by match to protein family HMM PF02831; gpW 1569402 6969495 ECH74115_1621 Escherichia coli O157:H7 str. EC4115 gpW YP_002270075.1 1569196 D 444450 CDS YP_002270076.1 209398709 6970146 1569399..1571000 1 NC_011353.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1571000 6970146 ECH74115_1622 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002270076.1 1569399 D 444450 CDS YP_002270077.1 209398131 6969781 1570981..1572300 1 NC_011353.1 identified by match to protein family HMM PF01343; minor capsid protein C 1572300 6969781 ECH74115_1623 Escherichia coli O157:H7 str. EC4115 minor capsid protein C YP_002270077.1 1570981 D 444450 CDS YP_002270078.1 209397545 6969153 1572310..1572642 1 NC_011353.1 identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1572642 6969153 ECH74115_1624 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda head decoration protein D YP_002270078.1 1572310 D 444450 CDS YP_002270079.1 209396940 6968519 1572698..1573723 1 NC_011353.1 identified by match to protein family HMM PF03864; phage major capsid protein E 1573723 6968519 ECH74115_1625 Escherichia coli O157:H7 str. EC4115 phage major capsid protein E YP_002270079.1 1572698 D 444450 CDS YP_002270080.1 209400378 6967878 1573765..1574163 1 NC_011353.1 DNA packaging protein FI 1574163 6967878 ECH74115_1626 Escherichia coli O157:H7 str. EC4115 DNA packaging protein FI YP_002270080.1 1573765 D 444450 CDS YP_002270081.1 209399790 6971578 1574175..1574528 1 NC_011353.1 identified by match to protein family HMM PF05354; phage Head-Tail Attachment 1574528 6971578 ECH74115_1627 Escherichia coli O157:H7 str. EC4115 phage Head-Tail Attachment YP_002270081.1 1574175 D 444450 CDS YP_002270082.1 209400079 6970947 1574540..1575118 1 NC_011353.1 identified by match to protein family HMM PF06763; prophage minor tail protein Z 1575118 6970947 ECH74115_1628 Escherichia coli O157:H7 str. EC4115 prophage minor tail protein Z YP_002270082.1 1574540 D 444450 CDS YP_002270083.1 209398613 6971258 1575115..1575510 1 NC_011353.1 identified by match to protein family HMM PF06141; phage minor tail protein U 1575510 6971258 ECH74115_1629 Escherichia coli O157:H7 str. EC4115 phage minor tail protein U YP_002270083.1 1575115 D 444450 CDS YP_002270084.1 209397999 6969676 1575518..1576258 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 1576258 6969676 ECH74115_1630 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002270084.1 1575518 D 444450 CDS YP_002270085.1 209397262 6969010 1576274..1576696 1 NC_011353.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 1576696 6969010 ECH74115_1631 Escherichia coli O157:H7 str. EC4115 phage minor tail protein G YP_002270085.1 1576274 D 444450 CDS YP_002270086.1 209398841 6968220 1576678..1577112 1 NC_011353.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 1577112 6968220 ECH74115_1632 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002270086.1 1576678 D 444450 CDS YP_002270087.1 209400998 6969925 1577105..1579654 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1579654 6969925 ECH74115_1633 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002270087.1 1577105 D 444450 CDS YP_002270088.1 209396388 6972240 1579651..1579980 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 1579980 6972240 ECH74115_1634 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002270088.1 1579651 D 444450 CDS YP_002270089.1 209395820 6967294 1579980..1580678 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1580678 6967294 ECH74115_1635 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002270089.1 1579980 D 444450 CDS YP_002270090.1 209397722 6966677 1580684..1581427 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 1581427 6966677 ECH74115_1636 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002270090.1 1580684 D 444450 CDS YP_002270091.1 209398285 6968707 1581424..1581996 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1581996 6968707 ECH74115_1637 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002270091.1 1581424 D 444450 CDS YP_002270092.1 209397540 6969319 1582057..1585455 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 1585455 6969319 ECH74115_1638 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270092.1 1582057 D 444450 CDS YP_002270093.1 209399466 6968514 1585522..1586121 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 1586121 6968514 ECH74115_1639 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002270093.1 1585522 D 444450 CDS YP_002270094.1 209400715 6970598 complement(1586122..1586295) 1 NC_011353.1 hypothetical protein 1586295 6970598 ECH74115_1640 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270094.1 1586122 R 444450 CDS YP_002270095.1 209400165 6971939 complement(1586683..1587420) 1 NC_011353.1 hypothetical protein 1587420 6971939 ECH74115_1641 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270095.1 1586683 R 444450 CDS YP_002270096.1 209399679 6971351 1587456..1587590 1 NC_011353.1 identified by glimmer; hypothetical protein 1587590 6971351 ECH74115_1642 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270096.1 1587456 D 444450 CDS YP_002270097.1 209400441 6970828 1587551..1589101 1 NC_011353.1 identified by match to protein family HMM PF03335; match to protein family HMM PF03406; match to protein family HMM PF07484; prophage tail fiber domain-containing protein 1589101 6970828 ECH74115_1643 Escherichia coli O157:H7 str. EC4115 prophage tail fiber domain-containing protein YP_002270097.1 1587551 D 444450 CDS YP_002270098.1 209398519 6971644 1589101..1589682 1 NC_011353.1 identified by match to protein family HMM PF02413; tail fiber assembly protein 1589682 6971644 ECH74115_1644 Escherichia coli O157:H7 str. EC4115 tail fiber assembly protein YP_002270098.1 1589101 D 444450 CDS YP_002270099.1 209399272 6969578 complement(1589802..1590692) 1 NC_011353.1 identified by match to protein family HMM PF05067; catalase 1590692 6969578 ECH74115_1645 Escherichia coli O157:H7 str. EC4115 catalase YP_002270099.1 1589802 R 444450 CDS YP_002270100.1 209398836 6970388 complement(1590711..1591217) 1 NC_011353.1 identified by match to protein family HMM PF05974; protein YciE 1591217 6970388 ECH74115_1646 Escherichia coli O157:H7 str. EC4115 protein YciE YP_002270100.1 1590711 R 444450 CDS YP_002270101.1 209399627 6969920 complement(1591254..1591754) 1 NC_011353.1 identified by match to protein family HMM PF05974; YciF protein 1591754 6969920 ECH74115_1647 Escherichia coli O157:H7 str. EC4115 YciF protein YP_002270101.1 1591254 R 444450 CDS YP_002270102.1 209400055 6970771 complement(1591833..1592015) 1 NC_011353.1 hypothetical protein 1592015 6970771 ECH74115_1648 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270102.1 1591833 R 444450 CDS YP_002270103.1 209400821 6971234 1593238..1593486 1 NC_011353.1 hypothetical protein 1593486 6971234 ECH74115_1649 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270103.1 1593238 D 444450 CDS YP_002270104.1 209395935 6972049 1593939..1594286 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 1594286 6972049 ECH74115_1650 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002270104.1 1593939 D 444450 CDS YP_002270105.1 209396349 6966802 1594336..1595874 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 1595874 6966802 ECH74115_1651 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002270105.1 1594336 D 444450 CDS YP_002270106.1 209400030 6967251 complement(1596177..1597661) 1 NC_011353.1 identified by match to protein family HMM PF00561; match to protein family HMM PF08386; hypothetical protein 1597661 6967251 ECH74115_1652 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270106.1 1596177 R 444450 CDS YP_002270107.1 209400792 6971205 complement(1597848..1598801) 1 NC_011353.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 1598801 6971205 ECH74115_1653 Escherichia coli O157:H7 str. EC4115 outer membrane protease YP_002270107.1 1597848 R 444450 CDS YP_002270108.1 209396051 6972018 1598936..1599064 1 NC_011353.1 identified by glimmer; hypothetical protein 1599064 6972018 ECH74115_1654 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270108.1 1598936 D 444450 CDS YP_002270109.1 209396624 6966928 1599300..1599884 1 NC_011353.1 identified by match to protein family HMM PF01381; helix-turn-helix domain-containing protein 1599884 6966928 ECH74115_1655 Escherichia coli O157:H7 str. EC4115 helix-turn-helix domain-containing protein YP_002270109.1 1599300 D 444450 CDS YP_002270110.1 209397558 6967544 1600058..1600384 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 1600384 6967544 ECH74115_1656 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002270110.1 1600058 D 444450 CDS YP_002270111.1 209398251 6968534 1600381..1601271 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 1601271 6968534 ECH74115_1657 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002270111.1 1600381 D 444450 CDS YP_002270112.1 209399080 6969283 1601355..1602065 1 NC_011353.1 identified by glimmer; hypothetical protein 1602065 6969283 ECH74115_1658 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270112.1 1601355 D 444450 CDS YP_002270113.1 209399824 6970182 complement(1602437..1602703) 1 NC_011353.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1602703 minE 6970182 minE Escherichia coli O157:H7 str. EC4115 cell division topological specificity factor MinE YP_002270113.1 1602437 R 444450 CDS YP_002270114.1 209400798 6970981 complement(1602707..1603519) 1 NC_011353.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1603519 minD 6970981 minD Escherichia coli O157:H7 str. EC4115 cell division inhibitor MinD YP_002270114.1 1602707 R 444450 CDS YP_002270115.1 209395883 6972026 complement(1603543..1604238) 1 NC_011353.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1604238 minC 6972026 minC Escherichia coli O157:H7 str. EC4115 septum formation inhibitor YP_002270115.1 1603543 R 444450 CDS YP_002270116.1 209400860 6966747 1604758..1605126 1 NC_011353.1 identified by match to protein family HMM PF05666; fels-1 Prophage Protein 1605126 6966747 ECH74115_1662 Escherichia coli O157:H7 str. EC4115 fels-1 Prophage Protein YP_002270116.1 1604758 D 444450 CDS YP_002270117.1 209397916 6972091 complement(1605229..1605630) 1 NC_011353.1 identified by match to protein family HMM PF04151; hypothetical protein 1605630 6972091 ECH74115_1663 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270117.1 1605229 R 444450 CDS YP_002270118.1 209397325 6968915 1605701..1605859 1 NC_011353.1 hypothetical protein 1605859 6968915 ECH74115_1664 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270118.1 1605701 D 444450 CDS YP_002270119.1 209397771 6968289 1605838..1606164 1 NC_011353.1 hypothetical protein 1606164 6968289 ECH74115_1665 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270119.1 1605838 D 444450 CDS YP_002270120.1 209396998 6968759 1606236..1606895 1 NC_011353.1 identified by match to protein family HMM PF01557; hypothetical protein 1606895 6968759 ECH74115_1666 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270120.1 1606236 D 444450 CDS YP_002270121.1 209399596 6967940 1606957..1607433 1 NC_011353.1 identified by match to protein family HMM PF03692; hypothetical protein 1607433 6967940 ECH74115_1667 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270121.1 1606957 D 444450 CDS YP_002270122.1 209398688 6970737 complement(1607640..1608695) 1 NC_011353.1 Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E 1608695 hlyE 6970737 hlyE Escherichia coli O157:H7 str. EC4115 hemolysin E YP_002270122.1 1607640 R 444450 CDS YP_002270123.1 209400795 6972318 1608924..1609343 1 NC_011353.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1609343 umuD 6972318 umuD Escherichia coli O157:H7 str. EC4115 DNA polymerase V subunit UmuD YP_002270123.1 1608924 D 444450 CDS YP_002270124.1 209400560 6972022 1609343..1610611 1 NC_011353.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1610611 umuC 6972022 umuC Escherichia coli O157:H7 str. EC4115 DNA polymerase V subunit UmuC YP_002270124.1 1609343 D 444450 CDS YP_002270125.1 209397308 6971769 complement(1610657..1611193) 1 NC_011353.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1611193 dsbB 6971769 dsbB Escherichia coli O157:H7 str. EC4115 disulfide bond formation protein B YP_002270125.1 1610657 R 444450 CDS YP_002270126.1 209400416 6968270 complement(1611333..1612874) 1 NC_011353.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1612874 nhaB 6968270 nhaB Escherichia coli O157:H7 str. EC4115 sodium/proton antiporter YP_002270126.1 1611333 R 444450 CDS YP_002270127.1 209396023 6971617 1613096..1613815 1 NC_011353.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1613815 fadR 6971617 fadR Escherichia coli O157:H7 str. EC4115 fatty acid metabolism regulator YP_002270127.1 1613096 D 444450 CDS YP_002270128.1 209396917 6966897 complement(1613867..1615399) 1 NC_011353.1 identified by match to protein family HMM PF04293; SpoVR family protein 1615399 6966897 ECH74115_1675 Escherichia coli O157:H7 str. EC4115 SpoVR family protein YP_002270128.1 1613867 R 444450 CDS YP_002270129.1 209395760 6967855 1615756..1617060 1 NC_011353.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1617060 dadA 6967855 dadA Escherichia coli O157:H7 str. EC4115 D-amino acid dehydrogenase small subunit YP_002270129.1 1615756 D 444450 CDS YP_002270130.1 209396444 6966615 1617070..1618140 1 NC_011353.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1618140 dadX 6966615 dadX Escherichia coli O157:H7 str. EC4115 alanine racemase YP_002270130.1 1617070 D 444450 CDS YP_002270131.1 209397217 6967354 complement(1618529..1620265) 1 NC_011353.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1620265 6967354 ECH74115_1678 Escherichia coli O157:H7 str. EC4115 potassium/proton antiporter YP_002270131.1 1618529 R 444450 CDS YP_002270132.1 209397773 6968175 complement(1620361..1621275) 1 NC_011353.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1621275 ldcA 6968175 ldcA Escherichia coli O157:H7 str. EC4115 L,D-carboxypeptidase A YP_002270132.1 1620361 R 444450 CDS YP_002270133.1 209400733 6968761 1621375..1621986 1 NC_011353.1 identified by match to protein family HMM PF01464; membrane-bound lytic murein transglycosylase E 1621986 mltE 6968761 mltE Escherichia coli O157:H7 str. EC4115 membrane-bound lytic murein transglycosylase E YP_002270133.1 1621375 D 444450 CDS YP_002270134.1 209398957 6971957 complement(1621988..1622143) 1 NC_011353.1 YcgR family protein 1622143 6971957 ECH74115_1681 Escherichia coli O157:H7 str. EC4115 YcgR family protein YP_002270134.1 1621988 R 444450 CDS YP_002270135.1 209396595 6970051 complement(1622095..1623255) 1 NC_011353.1 hypothetical protein 1623255 6970051 ECH74115_1682 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270135.1 1622095 R 444450 CDS YP_002270136.1 209399605 6967512 1623600..1623803 1 NC_011353.1 identified by glimmer; hypothetical protein 1623803 6967512 ECH74115_1683 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270136.1 1623600 D 444450 CDS YP_002270137.1 209398838 6970747 complement(1624099..1625190) 1 NC_011353.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1625190 engD 6970747 engD Escherichia coli O157:H7 str. EC4115 GTP-dependent nucleic acid-binding protein EngD YP_002270137.1 1624099 R 444450 CDS YP_002270138.1 209398573 6969922 complement(1625307..1625891) 1 NC_011353.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1625891 pth 6969922 pth Escherichia coli O157:H7 str. EC4115 peptidyl-tRNA hydrolase YP_002270138.1 1625307 R 444450 CDS YP_002270139.1 209399328 6969634 1626169..1626447 1 NC_011353.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1626447 6969634 ECH74115_1686 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270139.1 1626169 D 444450 CDS YP_002270140.1 209397423 6970448 complement(1626502..1628181) 1 NC_011353.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1628181 ychM 6970448 ychM Escherichia coli O157:H7 str. EC4115 sulfate transporter YchM YP_002270140.1 1626502 R 444450 CDS YP_002270141.1 209398206 6968392 complement(1628306..1629253) 1 NC_011353.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1629253 prs 6968392 prs Escherichia coli O157:H7 str. EC4115 ribose-phosphate pyrophosphokinase YP_002270141.1 1628306 R 444450 CDS YP_002270142.1 209396316 6969234 complement(1629404..1630255) 1 NC_011353.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1630255 ipk 6969234 ipk Escherichia coli O157:H7 str. EC4115 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002270142.1 1629404 R 444450 CDS YP_002270143.1 209396893 6967212 complement(1630255..1630878) 1 NC_011353.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1630878 lolB 6967212 lolB Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein LolB YP_002270143.1 1630255 R 444450 CDS YP_002270144.1 209400470 6967831 1631092..1632348 1 NC_011353.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1632348 hemA 6967831 hemA Escherichia coli O157:H7 str. EC4115 glutamyl-tRNA reductase YP_002270144.1 1631092 D 444450 CDS YP_002270145.1 209398404 6971675 1632390..1633472 1 NC_011353.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1633472 prfA 6971675 prfA Escherichia coli O157:H7 str. EC4115 peptide chain release factor 1 YP_002270145.1 1632390 D 444450 CDS YP_002270146.1 209396125 6969450 1633472..1634305 1 NC_011353.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1634305 hemK 6969450 hemK Escherichia coli O157:H7 str. EC4115 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002270146.1 1633472 D 444450 CDS YP_002270147.1 209398211 6967006 1634302..1634694 1 NC_011353.1 identified by match to protein family HMM PF04247; transcriptional regulator 1634694 6967006 ECH74115_1694 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002270147.1 1634302 D 444450 CDS YP_002270148.1 209397651 6969240 1634698..1635507 1 NC_011353.1 transcriptional regulator 1635507 sirB1 6969240 sirB1 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002270148.1 1634698 D 444450 CDS YP_002270149.1 209396605 6968634 1635543..1636397 1 NC_011353.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1636397 kdsA 6968634 kdsA Escherichia coli O157:H7 str. EC4115 2-dehydro-3-deoxyphosphooctonate aldolase YP_002270149.1 1635543 D 444450 CDS YP_002270150.1 209397643 6968751 complement(1637587..1638687) 1 NC_011353.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846; calcium/sodium:proton antiporter 1638687 6968751 ECH74115_1699 Escherichia coli O157:H7 str. EC4115 calcium/sodium:proton antiporter YP_002270150.1 1637587 R 444450 CDS YP_002270151.1 209399522 6968626 1638957..1639187 1 NC_011353.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1639187 chaB 6968626 chaB Escherichia coli O157:H7 str. EC4115 cation transport regulator YP_002270151.1 1638957 D 444450 CDS YP_002270152.1 209400559 6970658 1639348..1640043 1 NC_011353.1 identified by match to protein family HMM PF04752; chaC protein 1640043 6970658 ECH74115_1701 Escherichia coli O157:H7 str. EC4115 chaC protein YP_002270152.1 1639348 D 444450 CDS YP_002270153.1 209399976 6971768 complement(1640087..1640440) 1 NC_011353.1 identified by match to protein family HMM PF02635; dsrE family protein 1640440 6971768 ECH74115_1702 Escherichia coli O157:H7 str. EC4115 dsrE family protein YP_002270153.1 1640087 R 444450 CDS YP_002270154.1 209397160 6971148 1640590..1642020 1 NC_011353.1 hypothetical protein 1642020 6971148 ECH74115_1703 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270154.1 1640590 D 444450 CDS YP_002270155.1 209396600 6968112 complement(1642021..1642671) 1 NC_011353.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1642671 narL 6968112 narL Escherichia coli O157:H7 str. EC4115 transcriptional regulator NarL YP_002270155.1 1642021 R 444450 CDS YP_002270156.1 209395962 6967517 complement(1642664..1644460) 1 NC_011353.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarX 1644460 narX 6967517 narX Escherichia coli O157:H7 str. EC4115 nitrate/nitrite sensor protein NarX YP_002270156.1 1642664 R 444450 CDS YP_002270157.1 209400976 6966829 1644486..1644704 1 NC_011353.1 identified by glimmer; hypothetical protein 1644704 6966829 ECH74115_1706 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270157.1 1644486 D 444450 CDS YP_002270158.1 209400219 6972216 1644799..1646190 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 1 1646190 narK 6972216 narK Escherichia coli O157:H7 str. EC4115 nitrite extrusion protein 1 YP_002270158.1 1644799 D 444450 CDS YP_002270159.1 209399352 6971407 1646583..1650326 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase 1 subunit alpha 1650326 narG 6971407 narG Escherichia coli O157:H7 str. EC4115 nitrate reductase 1 subunit alpha YP_002270159.1 1646583 D 444450 CDS YP_002270160.1 209398625 6970473 1650323..1651861 1 NC_011353.1 identified by match to protein family HMM TIGR01660; nitrate reductase 1 subunit beta 1651861 narH 6970473 narH Escherichia coli O157:H7 str. EC4115 nitrate reductase 1 subunit beta YP_002270160.1 1650323 D 444450 CDS YP_002270161.1 209397903 6969688 1651858..1652568 1 NC_011353.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 1 1652568 narJ 6969688 narJ Escherichia coli O157:H7 str. EC4115 nitrate reductase molybdenum cofactor assembly chaperone 1 YP_002270161.1 1651858 D 444450 CDS YP_002270162.1 209397147 6968901 1652568..1653245 1 NC_011353.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase 1 subunit gamma 1653245 narI 6968901 narI Escherichia coli O157:H7 str. EC4115 respiratory nitrate reductase 1 subunit gamma YP_002270162.1 1652568 D 444450 CDS YP_002270163.1 209396262 6972428 complement(1654323..1655165) 1 NC_011353.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1655165 purU 6972428 purU Escherichia coli O157:H7 str. EC4115 formyltetrahydrofolate deformylase YP_002270163.1 1654323 R 444450 CDS YP_002270164.1 209397422 6967155 complement(1655215..1655694) 1 NC_011353.1 identified by match to protein family HMM PF02810; hypothetical protein 1655694 6967155 ECH74115_1718 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270164.1 1655215 R 444450 CDS YP_002270165.1 209398050 6968391 1655747..1656691 1 NC_011353.1 identified by match to protein family HMM PF01734; hypothetical protein 1656691 6968391 ECH74115_1719 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270165.1 1655747 D 444450 CDS YP_002270166.1 209396201 6969065 1656783..1657796 1 NC_011353.1 identified by match to protein family HMM PF00072; response regulator of RpoS 1657796 6969065 ECH74115_1720 Escherichia coli O157:H7 str. EC4115 response regulator of RpoS YP_002270166.1 1656783 D 444450 CDS YP_002270167.1 209396952 6967088 1657998..1658906 1 NC_011353.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1658906 galU 6967088 galU Escherichia coli O157:H7 str. EC4115 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_002270167.1 1657998 D 444450 CDS YP_002270168.1 209399686 6967890 complement(1659050..1659463) 1 NC_011353.1 identified by match to protein family HMM PF00816; global DNA-binding transcriptional dual regulator H-NS 1659463 hns 6967890 hns Escherichia coli O157:H7 str. EC4115 global DNA-binding transcriptional dual regulator H-NS YP_002270168.1 1659050 R 444450 CDS YP_002270169.1 209400579 6970835 complement(1659555..1659683) 1 NC_011353.1 identified by glimmer; hypothetical protein 1659683 6970835 ECH74115_1723 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270169.1 1659555 R 444450 CDS YP_002270170.1 209398636 6971790 1660067..1660684 1 NC_011353.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1660684 tdk 6971790 tdk Escherichia coli O157:H7 str. EC4115 thymidine kinase YP_002270170.1 1660067 D 444450 CDS YP_002270171.1 209397364 6969701 complement(1660985..1663660) 1 NC_011353.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1663660 adhE 6969701 adhE Escherichia coli O157:H7 str. EC4115 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002270171.1 1660985 R 444450 CDS YP_002270172.1 209398127 6968331 1664137..1664784 1 NC_011353.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1664784 6968331 ECH74115_1726 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270172.1 1664137 D 444450 CDS YP_002270173.1 209399730 6969149 1664811..1664966 1 NC_011353.1 identified by glimmer; hypothetical protein 1664966 6969149 ECH74115_1728 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270173.1 1664811 D 444450 CDS YP_002270174.1 209400038 6967073 1665477..1667153 1 NC_011353.1 identified by match to protein family HMM PF00496; oligopeptide ABC transporter substrate-binding protein 1667153 oppA 6967073 oppA Escherichia coli O157:H7 str. EC4115 oligopeptide ABC transporter substrate-binding protein YP_002270174.1 1665477 D 444450 CDS YP_002270175.1 209398544 6971213 1667239..1668159 1 NC_011353.1 identified by match to protein family HMM PF00528; oligopeptide transporter permease 1668159 oppB 6971213 oppB Escherichia coli O157:H7 str. EC4115 oligopeptide transporter permease YP_002270175.1 1667239 D 444450 CDS YP_002270176.1 209399648 6969603 1668177..1669082 1 NC_011353.1 identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease OppC 1669082 oppC 6969603 oppC Escherichia coli O157:H7 str. EC4115 oligopeptide ABC transporter permease OppC YP_002270176.1 1668177 D 444450 CDS YP_002270177.1 209397436 6970793 1669094..1670107 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1670107 oppD 6970793 oppD Escherichia coli O157:H7 str. EC4115 oligopeptide ABC transporter ATP-binding protein YP_002270177.1 1669094 D 444450 CDS YP_002270178.1 209397856 6968405 1670104..1671108 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein OppF 1671108 oppF 6968405 oppF Escherichia coli O157:H7 str. EC4115 oligopeptide ABC transporter ATP-binding protein OppF YP_002270178.1 1670104 D 444450 CDS YP_002270179.1 209396235 6968848 complement(1671161..1671490) 1 NC_011353.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1671490 6968848 ECH74115_1734 Escherichia coli O157:H7 str. EC4115 dsDNA-mimic protein YP_002270179.1 1671161 R 444450 CDS YP_002270180.1 209399735 6967126 complement(1671525..1672985) 1 NC_011353.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1672985 cls 6967126 cls Escherichia coli O157:H7 str. EC4115 cardiolipin synthetase YP_002270180.1 1671525 R 444450 CDS YP_002270181.1 209400463 6970889 1673149..1673301 1 NC_011353.1 hypothetical protein 1673301 6970889 ECH74115_1736 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270181.1 1673149 D 444450 CDS YP_002270182.1 209398569 6971668 complement(1673356..1674564) 1 NC_011353.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885; voltage-gated potassium channel 1674564 kch 6971668 kch Escherichia coli O157:H7 str. EC4115 voltage-gated potassium channel YP_002270182.1 1673356 R 444450 CDS YP_002270183.1 209396152 6969630 complement(1674910..1675206) 1 NC_011353.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1675206 6969630 ECH74115_1738 Escherichia coli O157:H7 str. EC4115 YciI-like protein YP_002270183.1 1674910 R 444450 CDS YP_002270184.1 209396499 6967035 1675430..1676149 1 NC_011353.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1676149 tonB 6967035 tonB Escherichia coli O157:H7 str. EC4115 transporter YP_002270184.1 1675430 D 444450 CDS YP_002270185.1 209400218 6967411 complement(1676189..1676587) 1 NC_011353.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1676587 yciA 6967411 yciA Escherichia coli O157:H7 str. EC4115 acyl-CoA thioester hydrolase YP_002270185.1 1676189 R 444450 CDS YP_002270186.1 209400640 6971406 complement(1676692..1677231) 1 NC_011353.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1677231 ispZ 6971406 ispZ Escherichia coli O157:H7 str. EC4115 intracellular septation protein A YP_002270186.1 1676692 R 444450 CDS YP_002270187.1 209397338 6969443 1678361..1678999 1 NC_011353.1 receptor for colicin S4; outer membrane protein W 1678999 ompW 6969443 ompW Escherichia coli O157:H7 str. EC4115 outer membrane protein W YP_002270187.1 1678361 D 444450 CDS YP_002270188.1 209398107 6968303 complement(1679045..1680175) 1 NC_011353.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; site-specific recombinase, phage integrase family 1680175 6968303 ECH74115_1744 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002270188.1 1679045 R 444450 CDS YP_002270189.1 209396209 6969126 complement(1680466..1682937) 1 NC_011353.1 identified by match to protein family HMM PF00929; exonuclease family protein 1682937 6969126 ECH74115_1745 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002270189.1 1680466 R 444450 CDS YP_002270190.1 209396947 6967097 complement(1683030..1683221) 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 1683221 6967097 ECH74115_1746 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270190.1 1683030 R 444450 CDS YP_002270191.1 209399736 6967885 complement(1683218..1683406) 1 NC_011353.1 identified by match to protein family HMM PF05358; DicB protein 1683406 6967885 ECH74115_1747 Escherichia coli O157:H7 str. EC4115 DicB protein YP_002270191.1 1683218 R 444450 CDS YP_002270192.1 209400630 6970890 1683423..1683545 1 NC_011353.1 identified by glimmer; hypothetical protein 1683545 6970890 ECH74115_1748 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270192.1 1683423 D 444450 CDS YP_002270193.1 209396133 6971843 1683965..1684198 1 NC_011353.1 hypothetical protein 1684198 6971843 ECH74115_1750 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270193.1 1683965 D 444450 CDS YP_002270194.1 209398042 6967016 complement(1684176..1684583) 1 NC_011353.1 hypothetical protein 1684583 6967016 ECH74115_1749 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270194.1 1684176 R 444450 CDS YP_002270195.1 209398380 6969056 complement(1684606..1684824) 1 NC_011353.1 identified by glimmer; hypothetical protein 1684824 6969056 ECH74115_1751 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270195.1 1684606 R 444450 CDS YP_002270196.1 209399121 6969423 complement(1684897..1685196) 1 NC_011353.1 hypothetical protein 1685196 6969423 ECH74115_1752 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270196.1 1684897 R 444450 CDS YP_002270197.1 209399922 6970223 1685586..1685720 1 NC_011353.1 identified by glimmer; hypothetical protein 1685720 6970223 ECH74115_1753 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270197.1 1685586 D 444450 CDS YP_002270198.1 209400666 6971086 1685944..1686171 1 NC_011353.1 DNA-binding transcriptional regulator DicC 1686171 6971086 ECH74115_1754 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator DicC YP_002270198.1 1685944 D 444450 CDS YP_002270199.1 209396707 6967541 1686677..1687717 1 NC_011353.1 hypothetical protein 1687717 6967541 ECH74115_1756 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270199.1 1686677 D 444450 CDS YP_002270200.1 209397572 6967631 1687749..1688171 1 NC_011353.1 hypothetical protein 1688171 6967631 ECH74115_1757 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270200.1 1687749 D 444450 CDS YP_002270201.1 209400379 6969695 1688975..1689100 1 NC_011353.1 hypothetical protein 1689100 6969695 ECH74115_1759 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270201.1 1688975 D 444450 CDS YP_002270202.1 209399779 6971579 1689811..1690557 1 NC_011353.1 porcine attaching-effacing associated protein 1690557 6971579 ECH74115_1760 Escherichia coli O157:H7 str. EC4115 porcine attaching-effacing associated protein YP_002270202.1 1689811 D 444450 CDS YP_002270203.1 209395841 6970936 1691269..1691526 1 NC_011353.1 hypothetical protein 1691526 6970936 ECH74115_1761 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270203.1 1691269 D 444450 CDS YP_002270204.1 209398225 6966698 complement(1691543..1691674) 1 NC_011353.1 identified by glimmer; hypothetical protein 1691674 6966698 ECH74115_1762 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270204.1 1691543 R 444450 CDS YP_002270205.1 209397660 6969255 1691876..1692922 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 1692922 6969255 ECH74115_1763 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270205.1 1691876 D 444450 CDS YP_002270206.1 209399411 6968643 1692935..1693294 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1693294 6968643 ECH74115_1764 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease RusA YP_002270206.1 1692935 D 444450 CDS YP_002270207.1 209400735 6970537 1693303..1693833 1 NC_011353.1 identified by match to protein family HMM PF06576; hypothetical protein 1693833 6970537 ECH74115_1765 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270207.1 1693303 D 444450 CDS YP_002270208.1 209400148 6971960 1694075..1694272 1 NC_011353.1 hypothetical protein 1694272 6971960 ECH74115_1766 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270208.1 1694075 D 444450 CDS YP_002270209.1 209399852 6971334 1694423..1695481 1 NC_011353.1 identified by match to protein family HMM PF01555; DNA methylase 1695481 6971334 ECH74115_1767 Escherichia coli O157:H7 str. EC4115 DNA methylase YP_002270209.1 1694423 D 444450 CDS YP_002270210.1 209395697 6968234 1697248..1697463 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 1697463 6968234 ECH74115_1772 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270210.1 1697248 D 444450 CDS YP_002270211.1 209396891 6966551 1697468..1697812 1 NC_011353.1 identified by match to protein family HMM PF07041; hypothetical protein 1697812 6966551 ECH74115_1773 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270211.1 1697468 D 444450 CDS YP_002270212.1 209400175 6967828 1697863..1698396 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 1698396 6967828 ECH74115_1774 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002270212.1 1697863 D 444450 CDS YP_002270213.1 209400757 6971362 1698667..1699236 1 NC_011353.1 anti-repressor protein Ant 1699236 6971362 ECH74115_1775 Escherichia coli O157:H7 str. EC4115 anti-repressor protein Ant YP_002270213.1 1698667 D 444450 CDS YP_002270214.1 209398704 6971982 1699236..1699382 1 NC_011353.1 hypothetical protein 1699382 6971982 ECH74115_1776 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270214.1 1699236 D 444450 CDS YP_002270215.1 209398614 6969776 1699390..1699857 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 1699857 6969776 ECH74115_1777 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002270215.1 1699390 D 444450 CDS YP_002270216.1 209397807 6969677 1699940..1700080 1 NC_011353.1 hypothetical protein 1700080 6969677 ECH74115_1778 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270216.1 1699940 D 444450 CDS YP_002270217.1 209395869 6968797 1700106..1700273 1 NC_011353.1 identified by glimmer; hypothetical protein 1700273 6968797 ECH74115_1779 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270217.1 1700106 D 444450 CDS YP_002270218.1 209400289 6966733 complement(1700717..1700881) 1 NC_011353.1 hypothetical protein 1700881 6966733 ECH74115_1780 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270218.1 1700717 R 444450 CDS YP_002270219.1 209397391 6972100 1701328..1701873 1 NC_011353.1 identified by match to protein family HMM PF07471; terminase small subunit 1701873 6972100 ECH74115_1782 Escherichia coli O157:H7 str. EC4115 terminase small subunit YP_002270219.1 1701328 D 444450 CDS YP_002270220.1 209397875 6968357 1701848..1703773 1 NC_011353.1 identified by match to protein family HMM PF05876; phage terminase large subunit 1703773 6968357 ECH74115_1783 Escherichia coli O157:H7 str. EC4115 phage terminase large subunit YP_002270220.1 1701848 D 444450 CDS YP_002270221.1 209398604 6968871 1703770..1703976 1 NC_011353.1 identified by match to protein family HMM PF02831; gpW 1703976 6968871 ECH74115_1784 Escherichia coli O157:H7 str. EC4115 gpW YP_002270221.1 1703770 D 444450 CDS YP_002270222.1 209399040 6969667 1703973..1705574 1 NC_011353.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1705574 6969667 ECH74115_1785 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002270222.1 1703973 D 444450 CDS YP_002270223.1 209399799 6970142 1705555..1706874 1 NC_011353.1 identified by match to protein family HMM PF01343; minor capsid protein C 1706874 6970142 ECH74115_1786 Escherichia coli O157:H7 str. EC4115 minor capsid protein C YP_002270223.1 1705555 D 444450 CDS YP_002270224.1 209400247 6970956 1706884..1707216 1 NC_011353.1 identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 1707216 6970956 ECH74115_1787 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda head decoration protein D YP_002270224.1 1706884 D 444450 CDS YP_002270225.1 209400938 6971438 1707272..1708297 1 NC_011353.1 identified by match to protein family HMM PF03864; phage major capsid protein E 1708297 6971438 ECH74115_1788 Escherichia coli O157:H7 str. EC4115 phage major capsid protein E YP_002270225.1 1707272 D 444450 CDS YP_002270226.1 209397610 6972175 1708339..1708737 1 NC_011353.1 DNA packaging protein FI 1708737 6972175 ECH74115_1789 Escherichia coli O157:H7 str. EC4115 DNA packaging protein FI YP_002270226.1 1708339 D 444450 CDS YP_002270227.1 209396627 6968591 1708749..1709102 1 NC_011353.1 identified by match to protein family HMM PF05354; phage Head-Tail Attachment 1709102 6968591 ECH74115_1790 Escherichia coli O157:H7 str. EC4115 phage Head-Tail Attachment YP_002270227.1 1708749 D 444450 CDS YP_002270228.1 209397023 6967547 1709117..1709650 1 NC_011353.1 identified by match to protein family HMM PF06763; prophage minor tail protein Z 1709650 6967547 ECH74115_1791 Escherichia coli O157:H7 str. EC4115 prophage minor tail protein Z YP_002270228.1 1709117 D 444450 CDS YP_002270229.1 209398674 6967967 1709647..1710042 1 NC_011353.1 identified by match to protein family HMM PF06141; phage minor tail protein U 1710042 6967967 ECH74115_1792 Escherichia coli O157:H7 str. EC4115 phage minor tail protein U YP_002270229.1 1709647 D 444450 CDS YP_002270230.1 209398584 6969744 1710050..1710802 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 1710802 6969744 ECH74115_1793 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002270230.1 1710050 D 444450 CDS YP_002270231.1 209400970 6971386 1711265..1711573 1 NC_011353.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 1711573 6971386 ECH74115_1795 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002270231.1 1711265 D 444450 CDS YP_002270232.1 209395830 6972210 1711617..1714262 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1714262 6972210 ECH74115_1796 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002270232.1 1711617 D 444450 CDS YP_002270233.1 209396396 6966687 1714259..1714588 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 1714588 6966687 ECH74115_1797 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002270233.1 1714259 D 444450 CDS YP_002270234.1 209397287 6967302 1714588..1715286 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1715286 6967302 ECH74115_1798 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002270234.1 1714588 D 444450 CDS YP_002270235.1 209400835 6968990 1716037..1716615 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1716615 6968990 ECH74115_1800 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002270235.1 1716037 D 444450 CDS YP_002270236.1 209400037 6972065 1716661..1716780 1 NC_011353.1 identified by glimmer; hypothetical protein 1716780 6972065 ECH74115_1801 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270236.1 1716661 D 444450 CDS YP_002270237.1 209395920 6971212 1716856..1719711 1 NC_011353.1 identified by match to protein family HMM PF09327; hypothetical protein 1719711 6971212 ECH74115_1802 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270237.1 1716856 D 444450 CDS YP_002270238.1 209398021 6966787 1719779..1720378 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 1720378 6966787 ECH74115_1803 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002270238.1 1719779 D 444450 CDS YP_002270239.1 209397061 6969034 1720530..1721834 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 1721834 6969034 ECH74115_1804 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002270239.1 1720530 D 444450 CDS YP_002270240.1 209399194 6968007 1721836..1722105 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 1722105 6968007 ECH74115_1805 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002270240.1 1721836 D 444450 CDS YP_002270241.1 209400510 6970302 complement(1722776..1722922) 1 NC_011353.1 identified by glimmer; hypothetical protein 1722922 6970302 ECH74115_1806 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270241.1 1722776 R 444450 CDS YP_002270242.1 209399714 6971715 complement(1723132..1724457) 1 NC_011353.1 NleA11 protein 1724457 6971715 ECH74115_1807 Escherichia coli O157:H7 str. EC4115 NleA11 protein YP_002270242.1 1723132 R 444450 CDS YP_002270243.1 209396860 6971446 1726284..1727195 1 NC_011353.1 non-LEE-encoded effector NleH 1727195 6971446 ECH74115_1809 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector NleH YP_002270243.1 1726284 D 444450 CDS YP_002270244.1 209399994 6969661 complement(1728796..1730334) 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 1730334 6969661 ECH74115_1812 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002270244.1 1728796 R 444450 CDS YP_002270245.1 209396403 6971166 complement(1730384..1730731) 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 1730731 6971166 ECH74115_1813 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002270245.1 1730384 R 444450 CDS YP_002270246.1 209395721 6967310 complement(1732437..1732967) 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 1732967 6967310 ECH74115_1814 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270246.1 1732437 R 444450 CDS YP_002270247.1 209398219 6966576 1733268..1733858 1 NC_011353.1 identified by match to protein family HMM PF03278; EspM3 protein 1733858 6966576 ECH74115_1815 Escherichia coli O157:H7 str. EC4115 EspM3 protein YP_002270247.1 1733268 D 444450 CDS YP_002270248.1 209398137 6971268 1737154..1737270 1 NC_011353.1 outer membrane protein W 1737270 6971268 ECH74115_1820 Escherichia coli O157:H7 str. EC4115 outer membrane protein W YP_002270248.1 1737154 D 444450 CDS YP_002270249.1 209397356 6969159 complement(1737316..1738446) 1 NC_011353.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; site-specific recombinase, phage integrase family 1738446 6969159 ECH74115_1821 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002270249.1 1737316 R 444450 CDS YP_002270250.1 209400511 6968323 complement(1738865..1741180) 1 NC_011353.1 identified by match to protein family HMM PF06630; exonuclease family protein 1741180 6968323 ECH74115_1822 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002270250.1 1738865 R 444450 CDS YP_002270251.1 209399784 6971716 complement(1741273..1741401) 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 1741401 6971716 ECH74115_1823 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270251.1 1741273 R 444450 CDS YP_002270252.1 209396205 6967269 1742044..1742208 1 NC_011353.1 hypothetical protein 1742208 6967269 ECH74115_1825 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270252.1 1742044 D 444450 CDS YP_002270253.1 209397564 6967092 complement(1742212..1742430) 1 NC_011353.1 identified by glimmer; hypothetical protein 1742430 6967092 ECH74115_1826 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270253.1 1742212 R 444450 CDS YP_002270254.1 209396698 6968540 complement(1742460..1742588) 1 NC_011353.1 identified by glimmer; hypothetical protein 1742588 6968540 ECH74115_1827 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270254.1 1742460 R 444450 CDS YP_002270255.1 209399324 6967622 complement(1742590..1742745) 1 NC_011353.1 identified by match to protein family HMM PF07151; hypothetical protein 1742745 6967622 ECH74115_1828 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270255.1 1742590 R 444450 CDS YP_002270256.1 209398534 6970444 complement(1742935..1743069) 1 NC_011353.1 HTH-type transcriptional regulator DicA 1743069 6970444 ECH74115_1829 Escherichia coli O157:H7 str. EC4115 HTH-type transcriptional regulator DicA YP_002270256.1 1742935 R 444450 CDS YP_002270257.1 209400244 6969593 1743108..1743314 1 NC_011353.1 identified by glimmer; hypothetical protein 1743314 6969593 ECH74115_1830 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270257.1 1743108 D 444450 CDS YP_002270258.1 209400538 6971435 1743420..1743647 1 NC_011353.1 DNA-binding transcriptional regulator DicC 1743647 6971435 ECH74115_1831 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator DicC YP_002270258.1 1743420 D 444450 CDS YP_002270259.1 209400774 6971745 1743691..1744182 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 1744182 6971745 ECH74115_1832 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270259.1 1743691 D 444450 CDS YP_002270260.1 209398708 6971999 1744154..1745194 1 NC_011353.1 hypothetical protein 1745194 6971999 ECH74115_1833 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270260.1 1744154 D 444450 CDS YP_002270261.1 209396406 6969780 1745226..1745648 1 NC_011353.1 hypothetical protein 1745648 6969780 ECH74115_1834 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270261.1 1745226 D 444450 CDS YP_002270262.1 209400170 6967313 1745683..1746453 1 NC_011353.1 identified by match to protein family HMM PF07789; hypothetical protein 1746453 6967313 ECH74115_1835 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270262.1 1745683 D 444450 CDS YP_002270263.1 209395933 6971357 1746469..1746864 1 NC_011353.1 identified by match to protein family HMM PF06163; hypothetical protein 1746864 6971357 ECH74115_1836 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270263.1 1746469 D 444450 CDS YP_002270264.1 209396367 6966800 1746921..1747277 1 NC_011353.1 hypothetical protein 1747277 6966800 ECH74115_1837 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270264.1 1746921 D 444450 CDS YP_002270265.1 209399402 6967270 1747326..1747538 1 NC_011353.1 hypothetical protein 1747538 6967270 ECH74115_1838 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270265.1 1747326 D 444450 CDS YP_002270266.1 209397974 6970528 1747574..1747945 1 NC_011353.1 hypothetical protein 1747945 6970528 ECH74115_1839 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270266.1 1747574 D 444450 CDS YP_002270267.1 209400748 6968983 1747942..1748304 1 NC_011353.1 identified by match to protein family HMM PF04448; hypothetical protein 1748304 6968983 ECH74115_1840 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270267.1 1747942 D 444450 CDS YP_002270268.1 209396271 6971973 1748375..1748524 1 NC_011353.1 hypothetical protein 1748524 6971973 ECH74115_1841 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270268.1 1748375 D 444450 CDS YP_002270269.1 209400387 6967164 1749146..1749403 1 NC_011353.1 hypothetical protein 1749403 6967164 ECH74115_1842 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270269.1 1749146 D 444450 CDS YP_002270270.1 209399600 6966856 1749753..1750802 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 1750802 6966856 ECH74115_1844 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270270.1 1749753 D 444450 CDS YP_002270271.1 209400198 6970741 1750815..1751189 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 1751189 6970741 ECH74115_1845 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease RusA YP_002270271.1 1750815 D 444450 CDS YP_002270272.1 209398106 6971385 1751186..1752007 1 NC_011353.1 identified by match to protein family HMM PF03589; antitermination protein Q 1752007 6971385 ECH74115_1846 Escherichia coli O157:H7 str. EC4115 antitermination protein Q YP_002270272.1 1751186 D 444450 CDS YP_002270273.1 209398925 6969125 1752234..1752431 1 NC_011353.1 hypothetical protein 1752431 6969125 ECH74115_1847 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270273.1 1752234 D 444450 CDS YP_002270274.1 209397302 6970018 1752582..1753640 1 NC_011353.1 identified by match to protein family HMM PF01555; DNA methylase 1753640 6970018 ECH74115_1848 Escherichia coli O157:H7 str. EC4115 DNA methylase YP_002270274.1 1752582 D 444450 CDS YP_002270275.1 209397440 6972352 complement(1753687..1753806) 1 NC_011353.1 identified by glimmer; hypothetical protein 1753806 6972352 ECH74115_1849 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270275.1 1753687 R 444450 CDS YP_002270276.1 209400104 6968410 complement(1753848..1753994) 1 NC_011353.1 hypothetical protein 1753994 6968410 ECH74115_1851 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270276.1 1753848 R 444450 CDS YP_002270277.1 209399249 6971286 1754235..1756181 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 1756181 6971286 ECH74115_1852 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270277.1 1754235 D 444450 CDS YP_002270278.1 209399905 6970363 1756178..1756303 1 NC_011353.1 hypothetical protein 1756303 6970363 ECH74115_1853 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270278.1 1756178 D 444450 CDS YP_002270279.1 209398806 6971069 1756316..1756495 1 NC_011353.1 identified by match to protein family HMM PF07125; hypothetical protein 1756495 6971069 ECH74115_1854 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270279.1 1756316 D 444450 CDS YP_002270280.1 209400966 6969886 1756536..1756781 1 NC_011353.1 identified by match to protein family HMM PF05696; hypothetical protein 1756781 6969886 ECH74115_1855 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270280.1 1756536 D 444450 CDS YP_002270281.1 209400185 6972206 1756859..1757074 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 1757074 6972206 ECH74115_1856 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270281.1 1756859 D 444450 CDS YP_002270282.1 209396430 6971372 1757078..1757635 1 NC_011353.1 hypothetical protein 1757635 6971372 ECH74115_1857 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270282.1 1757078 D 444450 CDS YP_002270283.1 209395700 6967337 1757672..1758205 1 NC_011353.1 identified by match to protein family HMM PF00959; lysozyme 1758205 6967337 ECH74115_1858 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002270283.1 1757672 D 444450 CDS YP_002270284.1 209397728 6966554 1758504..1758971 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 1758971 6966554 ECH74115_1859 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002270284.1 1758504 D 444450 CDS YP_002270285.1 209397215 6968713 1759384..1759860 1 NC_011353.1 identified by match to protein family HMM PF07278; bacteriophage terminase, small subunit 1759860 6968713 ECH74115_1860 Escherichia coli O157:H7 str. EC4115 bacteriophage terminase, small subunit YP_002270285.1 1759384 D 444450 CDS YP_002270286.1 209398699 6968173 1759857..1761980 1 NC_011353.1 identified by match to protein family HMM PF05876; phage terminase large subunit 1761980 6968173 ECH74115_1861 Escherichia coli O157:H7 str. EC4115 phage terminase large subunit YP_002270286.1 1759857 D 444450 CDS YP_002270287.1 209400870 6969771 1761977..1762189 1 NC_011353.1 hypothetical protein 1762189 6969771 ECH74115_1862 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270287.1 1761977 D 444450 CDS YP_002270288.1 209398750 6972102 1762189..1763691 1 NC_011353.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 1763691 6972102 ECH74115_1863 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002270288.1 1762189 D 444450 CDS YP_002270289.1 209399975 6969826 1763705..1765660 1 NC_011353.1 identified by match to protein family HMM PF00574; Clp protease domain-containing protein 1765660 clpP 6969826 clpP Escherichia coli O157:H7 str. EC4115 Clp protease domain-containing protein YP_002270289.1 1763705 D 444450 CDS YP_002270290.1 209399264 6971147 1765748..1766074 1 NC_011353.1 membrane protein 1766074 6971147 ECH74115_1865 Escherichia coli O157:H7 str. EC4115 membrane protein YP_002270290.1 1765748 D 444450 CDS YP_002270291.1 209398369 6970380 1766100..1766348 1 NC_011353.1 hypothetical protein 1766348 6970380 ECH74115_1866 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270291.1 1766100 D 444450 CDS YP_002270292.1 209398306 6969412 1766351..1766974 1 NC_011353.1 identified by match to protein family HMM PF06763; prophage minor tail protein Z 1766974 6969412 ECH74115_1867 Escherichia coli O157:H7 str. EC4115 prophage minor tail protein Z YP_002270292.1 1766351 D 444450 CDS YP_002270293.1 209397546 6969343 1766987..1767385 1 NC_011353.1 identified by match to protein family HMM PF06141; phage minor tail protein U 1767385 6969343 ECH74115_1868 Escherichia coli O157:H7 str. EC4115 phage minor tail protein U YP_002270293.1 1766987 D 444450 CDS YP_002270294.1 209396805 6968520 1767393..1768145 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 1768145 6968520 ECH74115_1869 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002270294.1 1767393 D 444450 CDS YP_002270295.1 209396028 6967737 1768159..1768581 1 NC_011353.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 1768581 6967737 ECH74115_1870 Escherichia coli O157:H7 str. EC4115 phage minor tail protein G YP_002270295.1 1768159 D 444450 CDS YP_002270296.1 209396731 6966904 1768632..1768916 1 NC_011353.1 identified by match to protein family HMM TIGR01715; phage tail assembly protein T 1768916 6966904 ECH74115_1871 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002270296.1 1768632 D 444450 CDS YP_002270297.1 209396157 6967657 1768960..1771605 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 1771605 6967657 ECH74115_1872 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002270297.1 1768960 D 444450 CDS YP_002270298.1 209398043 6967040 1771602..1771931 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 1771931 6967040 ECH74115_1873 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002270298.1 1771602 D 444450 CDS YP_002270299.1 209397581 6969057 1771931..1772629 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 1772629 6969057 ECH74115_1874 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002270299.1 1771931 D 444450 CDS YP_002270300.1 209396550 6968558 1772748..1773383 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 1773383 6968558 ECH74115_1875 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002270300.1 1772748 D 444450 CDS YP_002270301.1 209396136 6967464 1773380..1773958 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 1773958 6967464 ECH74115_1876 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002270301.1 1773380 D 444450 CDS YP_002270302.1 209400409 6967019 1774004..1774123 1 NC_011353.1 identified by glimmer; hypothetical protein 1774123 6967019 ECH74115_1877 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270302.1 1774004 D 444450 CDS YP_002270303.1 209399955 6971610 1774199..1777675 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 1777675 6971610 ECH74115_1878 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270303.1 1774199 D 444450 CDS YP_002270304.1 209399140 6971124 1777743..1778342 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 1778342 6971124 ECH74115_1879 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002270304.1 1777743 D 444450 CDS YP_002270305.1 209399581 6970246 complement(1778343..1778471) 1 NC_011353.1 hypothetical protein 1778471 6970246 ECH74115_1880 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270305.1 1778343 R 444450 CDS YP_002270306.1 209395732 6967362 1779442..1779720 1 NC_011353.1 identified by match to protein family HMM PF06820; tail fiber protein 1779720 6967362 ECH74115_1882 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002270306.1 1779442 D 444450 CDS YP_002270307.1 209398040 6966587 1779722..1779991 1 NC_011353.1 prophage tail fiber C-terminus family protein 1779991 6966587 ECH74115_1883 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002270307.1 1779722 D 444450 CDS YP_002270308.1 209397442 6969053 1780445..1780948 1 NC_011353.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 1780948 6969053 ECH74115_1884 Escherichia coli O157:H7 str. EC4115 IS1, transposase orfB YP_002270308.1 1780445 D 444450 CDS YP_002270309.1 209397172 6968412 1781124..1781714 1 NC_011353.1 OspG 1781714 6968412 ECH74115_1885 Escherichia coli O157:H7 str. EC4115 OspG YP_002270309.1 1781124 D 444450 CDS YP_002270310.1 209398998 6970360 1782576..1782692 1 NC_011353.1 hypothetical protein 1782692 6970360 ECH74115_1887 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270310.1 1782576 D 444450 CDS YP_002270311.1 209400415 6970097 complement(1782752..1783258) 1 NC_011353.1 identified by match to protein family HMM PF05974; hypothetical protein 1783258 6970097 ECH74115_1888 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270311.1 1782752 R 444450 CDS YP_002270312.1 209400109 6971616 complement(1783304..1783825) 1 NC_011353.1 identified by match to protein family HMM PF05974; YciF protein 1783825 yciF 6971616 yciF Escherichia coli O157:H7 str. EC4115 YciF protein YP_002270312.1 1783304 R 444450 CDS YP_002270313.1 209396856 6971292 complement(1783890..1784069) 1 NC_011353.1 hypothetical protein 1784069 6971292 ECH74115_1890 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270313.1 1783890 R 444450 CDS YP_002270314.1 209400776 6967791 1784146..1784289 1 NC_011353.1 identified by glimmer; hypothetical protein 1784289 6967791 ECH74115_1891 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270314.1 1784146 D 444450 CDS YP_002270315.1 209400034 6972001 complement(1784450..1785256) 1 NC_011353.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1785256 trpA 6972001 trpA Escherichia coli O157:H7 str. EC4115 tryptophan synthase subunit alpha YP_002270315.1 1784450 R 444450 CDS YP_002270316.1 209396478 6971209 complement(1785256..1786449) 1 NC_011353.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1786449 trpB 6971209 trpB Escherichia coli O157:H7 str. EC4115 tryptophan synthase subunit beta YP_002270316.1 1785256 R 444450 CDS YP_002270317.1 209395881 6967389 complement(1786461..1787819) 1 NC_011353.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1787819 trpC 6967389 trpC Escherichia coli O157:H7 str. EC4115 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002270317.1 1786461 R 444450 CDS YP_002270318.1 209397663 6966745 complement(1787823..1789418) 1 NC_011353.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1789418 trpD 6966745 trpD Escherichia coli O157:H7 str. EC4115 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_002270318.1 1787823 R 444450 CDS YP_002270319.1 209397030 6968646 complement(1789418..1790980) 1 NC_011353.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1790980 trpE 6968646 trpE Escherichia coli O157:H7 str. EC4115 anthranilate synthase component I YP_002270319.1 1789418 R 444450 CDS YP_002270320.1 209398686 6967974 1791254..1792135 1 NC_011353.1 identified by match to protein family HMM PF02811; phosphoesterase 1792135 6967974 ECH74115_1898 Escherichia coli O157:H7 str. EC4115 phosphoesterase YP_002270320.1 1791254 D 444450 CDS YP_002270321.1 209400954 6969756 1792096..1792752 1 NC_011353.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; hypothetical protein 1792752 6969756 ECH74115_1899 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270321.1 1792096 D 444450 CDS YP_002270322.1 209399841 6972192 1792780..1794363 1 NC_011353.1 hypothetical protein 1794363 6972192 ECH74115_1900 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270322.1 1792780 D 444450 CDS YP_002270323.1 209396722 6970998 1794576..1795448 1 NC_011353.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1795448 rluB 6970998 rluB Escherichia coli O157:H7 str. EC4115 23S rRNA pseudouridylate synthase B YP_002270323.1 1794576 D 444450 CDS YP_002270324.1 209398816 6967648 complement(1795488..1796078) 1 NC_011353.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1796078 btuR 6967648 btuR Escherichia coli O157:H7 str. EC4115 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002270324.1 1795488 R 444450 CDS YP_002270325.1 209399345 6969897 complement(1796075..1796833) 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase 1796833 6969897 ECH74115_1903 Escherichia coli O157:H7 str. EC4115 short chain dehydrogenase YP_002270325.1 1796075 R 444450 CDS YP_002270326.1 209397450 6970466 1797053..1798102 1 NC_011353.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1798102 sohB 6970466 sohB Escherichia coli O157:H7 str. EC4115 periplasmic protease YP_002270326.1 1797053 D 444450 CDS YP_002270327.1 209398051 6968420 complement(1798138..1798389) 1 NC_011353.1 hypothetical protein 1798389 6968420 ECH74115_1905 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270327.1 1798138 R 444450 CDS YP_002270328.1 209398456 6969066 1798769..1801366 1 NC_011353.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1801366 topA 6969066 topA Escherichia coli O157:H7 str. EC4115 DNA topoisomerase I YP_002270328.1 1798769 D 444450 CDS YP_002270329.1 209399190 6969509 1801576..1802550 1 NC_011353.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1802550 cysB 6969509 cysB Escherichia coli O157:H7 str. EC4115 transcriptional regulator CysB YP_002270329.1 1801576 D 444450 CDS YP_002270330.1 209399943 6970298 1802881..1803009 1 NC_011353.1 hypothetical protein 1803009 6970298 ECH74115_1908 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270330.1 1802881 D 444450 CDS YP_002270331.1 209396094 6971111 1803012..1803179 1 NC_011353.1 hypothetical protein 1803179 6971111 ECH74115_1909 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270331.1 1803012 D 444450 CDS YP_002270332.1 209396762 6966973 1803552..1806227 1 NC_011353.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1806227 acnA 6966973 acnA Escherichia coli O157:H7 str. EC4115 aconitate hydratase YP_002270332.1 1803552 D 444450 CDS YP_002270333.1 209397582 6967690 complement(1806291..1806881) 1 NC_011353.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1806881 ribA 6967690 ribA Escherichia coli O157:H7 str. EC4115 GTP cyclohydrolase II YP_002270333.1 1806291 R 444450 CDS YP_002270334.1 209398318 6968560 1807051..1807815 1 NC_011353.1 identified by match to protein family HMM PF01569; phosphatidylglycerophosphatase B 1807815 pgpB 6968560 pgpB Escherichia coli O157:H7 str. EC4115 phosphatidylglycerophosphatase B YP_002270334.1 1807051 D 444450 CDS YP_002270335.1 209397082 6969356 1807964..1808272 1 NC_011353.1 identified by match to protein family HMM PF06305; hypothetical protein 1808272 6969356 ECH74115_1913 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270335.1 1807964 D 444450 CDS YP_002270336.1 209396639 6968028 1808279..1809448 1 NC_011353.1 identified by match to protein family HMM PF07719; hypothetical protein 1809448 6968028 ECH74115_1914 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270336.1 1808279 D 444450 CDS YP_002270337.1 209395865 6967559 complement(1809482..1809622) 1 NC_011353.1 identified by glimmer; hypothetical protein 1809622 6967559 ECH74115_1915 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270337.1 1809482 R 444450 CDS YP_002270338.1 209397942 6966727 1809581..1810378 1 NC_011353.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1810378 pyrF 6966727 pyrF Escherichia coli O157:H7 str. EC4115 orotidine 5'-phosphate decarboxylase YP_002270338.1 1809581 D 444450 CDS YP_002270339.1 209397173 6968945 1810375..1810704 1 NC_011353.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1810704 6968945 ECH74115_1917 Escherichia coli O157:H7 str. EC4115 translation initiation factor Sui1 YP_002270339.1 1810375 D 444450 CDS YP_002270340.1 209399669 6968126 complement(1810830..1811048) 1 NC_011353.1 lipoprotein 1811048 6968126 ECH74115_1918 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270340.1 1810830 R 444450 CDS YP_002270341.1 209399633 6970816 complement(1811317..1812066) 1 NC_011353.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; DeoR family transcriptional regulator 1812066 6970816 ECH74115_1919 Escherichia coli O157:H7 str. EC4115 DeoR family transcriptional regulator YP_002270341.1 1811317 R 444450 CDS YP_002270342.1 209396230 6970778 complement(1812156..1812329) 1 NC_011353.1 hypothetical protein 1812329 6970778 ECH74115_1920 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270342.1 1812156 R 444450 CDS YP_002270343.1 209396001 6967607 complement(1814692..1816626) 1 NC_011353.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1816626 rnb 6967607 rnb Escherichia coli O157:H7 str. EC4115 exoribonuclease II YP_002270343.1 1814692 R 444450 CDS YP_002270344.1 209400889 6966873 complement(1816694..1817821) 1 NC_011353.1 hypothetical protein 1817821 6966873 ECH74115_1924 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270344.1 1816694 R 444450 CDS YP_002270345.1 209400132 6972122 complement(1817965..1818753) 1 NC_011353.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1818753 fabI 6972122 fabI Escherichia coli O157:H7 str. EC4115 enoyl-ACP reductase YP_002270345.1 1817965 R 444450 CDS YP_002270346.1 209398411 6971318 1819231..1819797 1 NC_011353.1 identified by match to protein family HMM PF00440; transcriptional regulator EefR 1819797 eefR 6971318 eefR Escherichia coli O157:H7 str. EC4115 transcriptional regulator EefR YP_002270346.1 1819231 D 444450 CDS YP_002270347.1 209399008 6969458 1819946..1821067 1 NC_011353.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; multidrug efflux transport protein EefA 1821067 eefA 6969458 eefA Escherichia coli O157:H7 str. EC4115 multidrug efflux transport protein EefA YP_002270347.1 1819946 D 444450 CDS YP_002270348.1 209396466 6968165 1824179..1825552 1 NC_011353.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845; multidrug efflux outer membrane protein EefC 1825552 eefC 6968165 eefC Escherichia coli O157:H7 str. EC4115 multidrug efflux outer membrane protein EefC YP_002270348.1 1824179 D 444450 CDS YP_002270349.1 209396100 6967377 1825561..1826724 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710; multidrug efflux transport protein EefD 1826724 eefD 6967377 eefD Escherichia coli O157:H7 str. EC4115 multidrug efflux transport protein EefD YP_002270349.1 1825561 D 444450 CDS YP_002270350.1 209400669 6966979 complement(1826776..1827582) 1 NC_011353.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein SapF 1827582 sapF 6966979 sapF Escherichia coli O157:H7 str. EC4115 peptide ABC transporter ATP-binding protein SapF YP_002270350.1 1826776 R 444450 CDS YP_002270351.1 209400028 6971887 complement(1827584..1828576) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; peptide ABC transporter ATP-binding protein SapD 1828576 sapD 6971887 sapD Escherichia coli O157:H7 str. EC4115 peptide ABC transporter ATP-binding protein SapD YP_002270351.1 1827584 R 444450 CDS YP_002270352.1 209399657 6971203 complement(1828576..1829466) 1 NC_011353.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease SapC 1829466 sapC 6971203 sapC Escherichia coli O157:H7 str. EC4115 peptide ABC transporter permease SapC YP_002270352.1 1828576 R 444450 CDS YP_002270353.1 209400983 6970804 complement(1829453..1830418) 1 NC_011353.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease SapB 1830418 sapB 6970804 sapB Escherichia coli O157:H7 str. EC4115 peptide ABC transporter permease SapB YP_002270353.1 1829453 R 444450 CDS YP_002270354.1 209399749 6972225 complement(1830415..1832034) 1 NC_011353.1 identified by match to protein family HMM PF00496; peptide ABC transporter substrate-binding protein 1832034 sapA 6972225 sapA Escherichia coli O157:H7 str. EC4115 peptide ABC transporter substrate-binding protein YP_002270354.1 1830415 R 444450 CDS YP_002270355.1 209395704 6970905 1832264..1832389 1 NC_011353.1 identified by glimmer; hypothetical protein 1832389 6970905 ECH74115_1937 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270355.1 1832264 D 444450 CDS YP_002270356.1 209396371 6966558 complement(1832371..1832616) 1 NC_011353.1 hypothetical protein 1832616 6966558 ECH74115_1936 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270356.1 1832371 R 444450 CDS YP_002270357.1 209398619 6967275 complement(1832750..1834135) 1 NC_011353.1 identified by match to protein family HMM PF00324; amino acid permease 1834135 6967275 ECH74115_1938 Escherichia coli O157:H7 str. EC4115 amino acid permease YP_002270357.1 1832750 R 444450 CDS YP_002270358.1 209398672 6969682 complement(1834438..1835856) 1 NC_011353.1 identified by match to protein family HMM PF00120; glutamate--putrescine ligase 1835856 puuA 6969682 puuA Escherichia coli O157:H7 str. EC4115 glutamate--putrescine ligase YP_002270358.1 1834438 R 444450 CDS YP_002270359.1 209400761 6969742 1836080..1836832 1 NC_011353.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1836832 puuD 6969742 puuD Escherichia coli O157:H7 str. EC4115 gamma-glutamyl-gamma-aminobutyrate hydrolase YP_002270359.1 1836080 D 444450 CDS YP_002270360.1 209400310 6971986 1836859..1837416 1 NC_011353.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1837416 puuR 6971986 puuR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor PuuR YP_002270360.1 1836859 D 444450 CDS YP_002270361.1 209396804 6971505 1837566..1839053 1 NC_011353.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1839053 puuC 6971505 puuC Escherichia coli O157:H7 str. EC4115 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_002270361.1 1837566 D 444450 CDS YP_002270362.1 209396047 6967736 1839055..1840335 1 NC_011353.1 identified by match to protein family HMM PF01266; gamma-glutamylputrescine oxidoreductase 1840335 puuB 6967736 puuB Escherichia coli O157:H7 str. EC4115 gamma-glutamylputrescine oxidoreductase YP_002270362.1 1839055 D 444450 CDS YP_002270363.1 209400873 6966924 1840373..1841638 1 NC_011353.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1841638 gabT1 6966924 gabT1 Escherichia coli O157:H7 str. EC4115 4-aminobutyrate transaminase YP_002270363.1 1840373 D 444450 CDS YP_002270364.1 209399768 6972105 complement(1841769..1842746) 1 NC_011353.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1842746 pspF 6972105 pspF Escherichia coli O157:H7 str. EC4115 phage shock protein operon transcriptional activator YP_002270364.1 1841769 R 444450 CDS YP_002270365.1 209399315 6970924 1842913..1843581 1 NC_011353.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1843581 pspA 6970924 pspA Escherichia coli O157:H7 str. EC4115 phage shock protein PspA YP_002270365.1 1842913 D 444450 CDS YP_002270366.1 209398552 6970434 1843635..1843859 1 NC_011353.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1843859 pspB 6970434 pspB Escherichia coli O157:H7 str. EC4115 phage shock protein B YP_002270366.1 1843635 D 444450 CDS YP_002270367.1 209395915 6969612 1843859..1844218 1 NC_011353.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1844218 pspC 6969612 pspC Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator PspC YP_002270367.1 1843859 D 444450 CDS YP_002270368.1 209397470 6966782 1844227..1844448 1 NC_011353.1 identified by match to protein family HMM PF09584; match to protein family HMM TIGR02979; peripheral inner membrane phage-shock protein 1844448 pspD 6966782 pspD Escherichia coli O157:H7 str. EC4115 peripheral inner membrane phage-shock protein YP_002270368.1 1844227 D 444450 CDS YP_002270369.1 209396979 6968441 1844523..1844837 1 NC_011353.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1844837 pspE 6968441 pspE Escherichia coli O157:H7 str. EC4115 thiosulfate:cyanide sulfurtransferase YP_002270369.1 1844523 D 444450 CDS YP_002270370.1 209396254 6967920 1844849..1844968 1 NC_011353.1 identified by glimmer; hypothetical protein 1844968 6967920 ECH74115_1951 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270370.1 1844849 D 444450 CDS YP_002270371.1 209400010 6968826 1848052..1848933 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; sugar ABC transporter permease 1848933 6968826 ECH74115_1956 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter permease YP_002270371.1 1848052 D 444450 CDS YP_002270372.1 209396657 6971184 1848920..1849762 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; sugar ABC transporter permease 1849762 6971184 ECH74115_1957 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter permease YP_002270372.1 1848920 D 444450 CDS YP_002270373.1 209398887 6967578 1849793..1850845 1 NC_011353.1 identified by match to protein family HMM PF00107; oxidoreductase, zinc-binding dehydrogenase family 1850845 6967578 ECH74115_1958 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002270373.1 1849793 D 444450 CDS YP_002270374.1 209400921 6969976 1850863..1851651 1 NC_011353.1 identified by match to protein family HMM PF01261; AP endonuclease, family 2 1851651 6969976 ECH74115_1959 Escherichia coli O157:H7 str. EC4115 AP endonuclease, family 2 YP_002270374.1 1850863 D 444450 CDS YP_002270375.1 209397813 6972158 1851661..1852716 1 NC_011353.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; gfo/idh/mocA family protein 1852716 6972158 ECH74115_1960 Escherichia coli O157:H7 str. EC4115 gfo/idh/mocA family protein YP_002270375.1 1851661 D 444450 CDS YP_002270376.1 209397081 6968804 1852713..1854980 1 NC_011353.1 identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; glycoside hydrolase 1854980 6968804 ECH74115_1961 Escherichia coli O157:H7 str. EC4115 glycoside hydrolase YP_002270376.1 1852713 D 444450 CDS YP_002270377.1 209400484 6968027 1854977..1855636 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009; beta-phosphoglucomutase 1855636 pgmB 6968027 pgmB Escherichia coli O157:H7 str. EC4115 beta-phosphoglucomutase YP_002270377.1 1854977 D 444450 CDS YP_002270378.1 209398922 6971689 1855650..1856732 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; sugar ABC transporter ATP-binding protein 1856732 6971689 ECH74115_1963 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter ATP-binding protein YP_002270378.1 1855650 D 444450 CDS YP_002270379.1 209395715 6970014 1856777..1857682 1 NC_011353.1 identified by match to protein family HMM PF09381; outer membrane protein G 1857682 ompG 6970014 ompG Escherichia coli O157:H7 str. EC4115 outer membrane protein G YP_002270379.1 1856777 D 444450 CDS YP_002270380.1 209396470 6966570 complement(1857793..1858791) 1 NC_011353.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 1858791 6966570 ECH74115_1965 Escherichia coli O157:H7 str. EC4115 LacI family transcriptional regulator YP_002270380.1 1857793 R 444450 CDS YP_002270381.1 209397259 6967381 1858946..1860343 1 NC_011353.1 identified by match to protein family HMM PF04317; hypothetical protein 1860343 6967381 ECH74115_1966 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270381.1 1858946 D 444450 CDS YP_002270382.1 209397939 6968217 1860340..1861401 1 NC_011353.1 identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein 1861401 6968217 ECH74115_1967 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270382.1 1860340 D 444450 CDS YP_002270383.1 209397678 6968942 1861549..1863090 1 NC_011353.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1863090 tyrR 6968942 tyrR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator TyrR YP_002270383.1 1861549 D 444450 CDS YP_002270384.1 209398083 6968661 complement(1863134..1863640) 1 NC_011353.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1863640 tpx 6968661 tpx Escherichia coli O157:H7 str. EC4115 thiol peroxidase YP_002270384.1 1863134 R 444450 CDS YP_002270385.1 209399075 6969100 1863759..1864724 1 NC_011353.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing protein 1864724 6969100 ECH74115_1971 Escherichia coli O157:H7 str. EC4115 mandelate racemase/muconate lactonizing protein YP_002270385.1 1863759 D 444450 CDS YP_002270386.1 209398476 6970177 complement(1864699..1865427) 1 NC_011353.1 identified by match to protein family HMM PF00246; murein peptide amidase A 1865427 6970177 ECH74115_1970 Escherichia coli O157:H7 str. EC4115 murein peptide amidase A YP_002270386.1 1864699 R 444450 CDS YP_002270387.1 209397780 6969532 complement(1865718..1866356) 1 NC_011353.1 NmrA family protein 1866356 6969532 ECH74115_1972 Escherichia coli O157:H7 str. EC4115 NmrA family protein YP_002270387.1 1865718 R 444450 CDS YP_002270388.1 209400056 6970836 complement(1867307..1868227) 1 NC_011353.1 identified by match to protein family HMM PF02129; hypothetical protein 1868227 6970836 ECH74115_1975 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270388.1 1867307 R 444450 CDS YP_002270389.1 209400888 6971235 1868365..1869264 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1869264 6971235 ECH74115_1976 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002270389.1 1868365 D 444450 CDS YP_002270390.1 209396617 6972121 1869600..1871213 1 NC_011353.1 identified by match to protein family HMM PF00496; periplasmic murein peptide-binding protein 1871213 mppA 6972121 mppA Escherichia coli O157:H7 str. EC4115 periplasmic murein peptide-binding protein YP_002270390.1 1869600 D 444450 CDS YP_002270391.1 209397381 6967536 complement(1871264..1872295) 1 NC_011353.1 identified by match to protein family HMM PF00924; transporter small conductance mechanosensitive ion channel family 1872295 6967536 ECH74115_1978 Escherichia coli O157:H7 str. EC4115 transporter small conductance mechanosensitive ion channel family YP_002270391.1 1871264 R 444450 CDS YP_002270392.1 209397767 6968347 1872539..1872796 1 NC_011353.1 hypothetical protein 1872796 6968347 ECH74115_1979 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270392.1 1872539 D 444450 CDS YP_002270393.1 209398539 6968755 complement(1872846..1873796) 1 NC_011353.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1873796 uspE 6968755 uspE Escherichia coli O157:H7 str. EC4115 universal stress protein UspE YP_002270393.1 1872846 R 444450 CDS YP_002270394.1 209399588 6969598 complement(1873948..1874700) 1 NC_011353.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1874700 fnr 6969598 fnr Escherichia coli O157:H7 str. EC4115 fumarate/nitrate reduction transcriptional regulator YP_002270394.1 1873948 R 444450 CDS YP_002270395.1 209399746 6970729 complement(1874895..1875410) 1 NC_011353.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1875410 ogt 6970729 ogt Escherichia coli O157:H7 str. EC4115 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_002270395.1 1874895 R 444450 CDS YP_002270396.1 209399301 6970902 complement(1875421..1876953) 1 NC_011353.1 identified by match to protein family HMM PF03806; match to protein family HMM TIGR00819; aminobenzoyl-glutamate transporter 1876953 abgT 6970902 abgT Escherichia coli O157:H7 str. EC4115 aminobenzoyl-glutamate transporter YP_002270396.1 1875421 R 444450 CDS YP_002270397.1 209398564 6970418 complement(1876984..1878429) 1 NC_011353.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein B 1878429 abgB 6970418 abgB Escherichia coli O157:H7 str. EC4115 aminobenzoyl-glutamate utilization protein B YP_002270397.1 1876984 R 444450 CDS YP_002270398.1 209397530 6969625 complement(1878429..1879739) 1 NC_011353.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein A 1879739 abgA 6969625 abgA Escherichia coli O157:H7 str. EC4115 aminobenzoyl-glutamate utilization protein A YP_002270398.1 1878429 R 444450 CDS YP_002270399.1 209396807 6968503 1879915..1880823 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 1880823 6968503 ECH74115_1986 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002270399.1 1879915 D 444450 CDS YP_002270400.1 209395705 6972291 1881153..1881716 1 NC_011353.1 identified by match to protein family HMM PF01713; Smr domain-containing protein 1881716 6972291 ECH74115_1988 Escherichia coli O157:H7 str. EC4115 Smr domain-containing protein YP_002270400.1 1881153 D 444450 CDS YP_002270401.1 209400929 6966559 complement(1881737..1883029) 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box-containing diguanylate cyclase 1883029 6966559 ECH74115_1989 Escherichia coli O157:H7 str. EC4115 sensory box-containing diguanylate cyclase YP_002270401.1 1881737 R 444450 CDS YP_002270402.1 209399691 6972166 1883224..1884207 1 NC_011353.1 identified by match to protein family HMM PF01544; zinc transporter 1884207 zntB 6972166 zntB Escherichia coli O157:H7 str. EC4115 zinc transporter YP_002270402.1 1883224 D 444450 CDS YP_002270403.1 209399223 6972288 1884685..1886058 1 NC_011353.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1886058 dbpA 6972288 dbpA Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase DbpA YP_002270403.1 1884685 D 444450 CDS YP_002270404.1 209398638 6970333 complement(1886187..1887122) 1 NC_011353.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1887122 6970333 ECH74115_1993 Escherichia coli O157:H7 str. EC4115 C32 tRNA thiolase YP_002270404.1 1886187 R 444450 CDS YP_002270405.1 209399053 6969704 complement(1887298..1887732) 1 NC_011353.1 identified by match to protein family HMM PF00582; universal stress protein F 1887732 uspF 6969704 uspF Escherichia coli O157:H7 str. EC4115 universal stress protein F YP_002270405.1 1887298 R 444450 CDS YP_002270406.1 209400785 6972301 complement(1889352..1892876) 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate-flavodoxin oxidoreductase 1892876 ydbK 6972301 ydbK Escherichia coli O157:H7 str. EC4115 pyruvate-flavodoxin oxidoreductase YP_002270406.1 1889352 R 444450 CDS YP_002270407.1 209400021 6972011 complement(1892947..1893063) 1 NC_011353.1 identified by glimmer; hypothetical protein 1893063 6972011 ECH74115_1999 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270407.1 1892947 R 444450 CDS YP_002270408.1 209397951 6971196 1893291..1893416 1 NC_011353.1 lipoprotein 1893416 6971196 ECH74115_2001 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270408.1 1893291 D 444450 CDS YP_002270409.1 209396024 6968955 complement(1893413..1893835) 1 NC_011353.1 identified by match to protein family HMM PF03724; heat-inducible protein 1893835 hslJ 6968955 hslJ Escherichia coli O157:H7 str. EC4115 heat-inducible protein YP_002270409.1 1893413 R 444450 CDS YP_002270410.1 209397196 6966898 complement(1893946..1894935) 1 NC_011353.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-lactate dehydrogenase 1894935 idhA 6966898 idhA Escherichia coli O157:H7 str. EC4115 D-lactate dehydrogenase YP_002270410.1 1893946 R 444450 CDS YP_002270411.1 209399144 6968152 1895143..1897782 1 NC_011353.1 identified by glimmer; hypothetical protein 1897782 6968152 ECH74115_2003 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270411.1 1895143 D 444450 CDS YP_002270412.1 209400469 6970251 1897779..1897964 1 NC_011353.1 lipoprotein 1897964 6970251 ECH74115_2004 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270412.1 1897779 D 444450 CDS YP_002270413.1 209396950 6971674 1897972..1898295 1 NC_011353.1 identified by match to protein family HMM PF07027; hypothetical protein 1898295 6971674 ECH74115_2005 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270413.1 1897972 D 444450 CDS YP_002270414.1 209398512 6969963 1904643..1905503 1 NC_011353.1 identified by match to protein family HMM PF00248; oxidoreductase 1905503 6969963 ECH74115_2008 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002270414.1 1904643 D 444450 CDS YP_002270415.1 209399276 6969570 1905484..1905597 1 NC_011353.1 identified by glimmer; hypothetical protein 1905597 6969570 ECH74115_2009 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270415.1 1905484 D 444450 CDS YP_002270416.1 209400439 6970392 1905567..1907873 1 NC_011353.1 identified by glimmer; hypothetical protein 1907873 6970392 ECH74115_2010 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270416.1 1905567 D 444450 CDS YP_002270417.1 209395890 6971642 1908044..1908649 1 NC_011353.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 1908649 6971642 ECH74115_2011 Escherichia coli O157:H7 str. EC4115 CDP-alcohol phosphatidyltransferase YP_002270417.1 1908044 D 444450 CDS YP_002270418.1 209396975 6966756 1908649..1909545 1 NC_011353.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1909545 cdsA2 6966756 cdsA2 Escherichia coli O157:H7 str. EC4115 phosphatidate cytidylyltransferase YP_002270418.1 1908649 D 444450 CDS YP_002270419.1 209397036 6967915 1909561..1911318 1 NC_011353.1 hypothetical protein 1911318 6967915 ECH74115_2013 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270419.1 1909561 D 444450 CDS YP_002270420.1 209398896 6967980 1911332..1912624 1 NC_011353.1 identified by match to protein family HMM PF00782; match to protein family HMM PF01569; PAP2 family protein 1912624 6967980 ECH74115_2014 Escherichia coli O157:H7 str. EC4115 PAP2 family protein YP_002270420.1 1911332 D 444450 CDS YP_002270421.1 209400143 6969985 complement(1912675..1913280) 1 NC_011353.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1913280 azoR 6969985 azoR Escherichia coli O157:H7 str. EC4115 azoreductase YP_002270421.1 1912675 R 444450 CDS YP_002270422.1 209400718 6971329 1913481..1917383 1 NC_011353.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1917383 hrpA 6971329 hrpA Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase HrpA YP_002270422.1 1913481 D 444450 CDS YP_002270423.1 209399027 6971942 1918115..1918297 1 NC_011353.1 hypothetical protein 1918297 6971942 ECH74115_2017 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270423.1 1918115 D 444450 CDS YP_002270424.1 209399610 6970127 1918284..1918715 1 NC_011353.1 hypothetical protein 1918715 6970127 ECH74115_2018 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270424.1 1918284 D 444450 CDS YP_002270425.1 209397880 6970754 1919104..1919217 1 NC_011353.1 hypothetical protein 1919217 6970754 ECH74115_2019 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270425.1 1919104 D 444450 CDS YP_002270426.1 209395974 6968876 1919333..1920133 1 NC_011353.1 identified by match to protein family HMM PF02698; hypothetical protein 1920133 6968876 ECH74115_2020 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270426.1 1919333 D 444450 CDS YP_002270427.1 209396361 6966843 1920330..1921769 1 NC_011353.1 NAD-linked; aldehyde dehydrogenase A 1921769 aldA 6966843 aldA Escherichia coli O157:H7 str. EC4115 aldehyde dehydrogenase A YP_002270427.1 1920330 D 444450 CDS YP_002270428.1 209399787 6967263 complement(1921811..1922812) 1 NC_011353.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase 1922812 gapC 6967263 gapC Escherichia coli O157:H7 str. EC4115 glyceraldehyde-3-phosphate dehydrogenase YP_002270428.1 1921811 R 444450 CDS YP_002270429.1 209400941 6970944 1923001..1923531 1 NC_011353.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1923531 6970944 ECH74115_2023 Escherichia coli O157:H7 str. EC4115 cytochrome b561 YP_002270429.1 1923001 D 444450 CDS YP_002270430.1 209399017 6972293 1923776..1923949 1 NC_011353.1 hypothetical protein 1923949 6972293 ECH74115_2025 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270430.1 1923776 D 444450 CDS YP_002270431.1 209400342 6970117 1924797..1926209 1 NC_011353.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein III 1926209 trg 6970117 trg Escherichia coli O157:H7 str. EC4115 methyl-accepting chemotaxis protein III YP_002270431.1 1924797 D 444450 CDS YP_002270432.1 209395969 6971539 complement(1926247..1927170) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1927170 6971539 ECH74115_2027 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002270432.1 1926247 R 444450 CDS YP_002270433.1 209396192 6966838 1927387..1928730 1 NC_011353.1 identified by match to protein family HMM PF07063; hypothetical protein 1928730 6966838 ECH74115_2028 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270433.1 1927387 D 444450 CDS YP_002270434.1 209396923 6967079 1928991..1930610 1 NC_011353.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1930610 mdoD 6967079 mdoD Escherichia coli O157:H7 str. EC4115 glucan biosynthesis protein D YP_002270434.1 1928991 D 444450 CDS YP_002270435.1 209398084 6967861 1930750..1930974 1 NC_011353.1 identified by match to protein family HMM PF04325; hypothetical protein 1930974 6967861 ECH74115_2030 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270435.1 1930750 D 444450 CDS YP_002270436.1 209399247 6971136 complement(1931568..1932548) 1 NC_011353.1 hypothetical protein 1932548 6971136 ECH74115_2032 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270436.1 1931568 R 444450 CDS YP_002270437.1 209396012 6970361 1932672..1933664 1 NC_011353.1 identified by match to protein family HMM PF03595; match to protein family HMM TIGR00816; potassium-tellurite ethidium and proflavin transporter 1933664 tehA 6970361 tehA Escherichia coli O157:H7 str. EC4115 potassium-tellurite ethidium and proflavin transporter YP_002270437.1 1932672 D 444450 CDS YP_002270438.1 209396414 6966885 1933661..1934254 1 NC_011353.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1934254 tehB 6966885 tehB Escherichia coli O157:H7 str. EC4115 tellurite resistance protein TehB YP_002270438.1 1933661 D 444450 CDS YP_002270439.1 209398678 6967321 1934558..1935226 1 NC_011353.1 lipoprotein 1935226 6967321 ECH74115_2036 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270439.1 1934558 D 444450 CDS YP_002270440.1 209397754 6968511 1936526..1937062 1 NC_011353.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 1937062 6968511 ECH74115_2039 Escherichia coli O157:H7 str. EC4115 DNA-binding protein YP_002270440.1 1936526 D 444450 CDS YP_002270441.1 209395986 6968741 1937093..1939096 1 NC_011353.1 identified by match to protein family HMM PF01136; U32 family peptidase 1939096 6968741 ECH74115_2040 Escherichia coli O157:H7 str. EC4115 U32 family peptidase YP_002270441.1 1937093 D 444450 CDS YP_002270442.1 209396538 6966857 complement(1939188..1939358) 1 NC_011353.1 hypothetical protein 1939358 6966857 ECH74115_2041 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270442.1 1939188 R 444450 CDS YP_002270443.1 209400773 6967451 complement(1939475..1939597) 1 NC_011353.1 identified by glimmer; hypothetical protein 1939597 6967451 ECH74115_2042 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270443.1 1939475 R 444450 CDS YP_002270444.1 209398671 6971998 1939841..1940278 1 NC_011353.1 identified by match to protein family HMM PF01381; match to protein family HMM PF03681; hypothetical protein 1940278 6971998 ECH74115_2043 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270444.1 1939841 D 444450 CDS YP_002270445.1 209399584 6969741 1940357..1941763 1 NC_011353.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; transcriptional regulator, GntR family/aminotransferase, classes I and II 1941763 6969741 ECH74115_2044 Escherichia coli O157:H7 str. EC4115 transcriptional regulator, GntR family/aminotransferase, classes I and II YP_002270445.1 1940357 D 444450 CDS YP_002270446.1 209397208 6970725 1942008..1943153 1 NC_011353.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 1943153 ydcS 6970725 ydcS Escherichia coli O157:H7 str. EC4115 ABC transporter substrate-binding protein YP_002270446.1 1942008 D 444450 CDS YP_002270447.1 209398098 6968166 1943171..1944184 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; ABC transporter ATP-binding protein 1944184 ydcT 6968166 ydcT Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002270447.1 1943171 D 444450 CDS YP_002270448.1 209397365 6969116 1944185..1945126 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 1945126 ydcU 6969116 ydcU Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002270448.1 1944185 D 444450 CDS YP_002270449.1 209396901 6968332 1945116..1945910 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 1945910 ydcV 6968332 ydcV Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002270449.1 1945116 D 444450 CDS YP_002270450.1 209399713 6967839 1945932..1947356 1 NC_011353.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1947356 ydcW 6967839 ydcW Escherichia coli O157:H7 str. EC4115 gamma-aminobutyraldehyde dehydrogenase YP_002270450.1 1945932 D 444450 CDS YP_002270451.1 209400466 6970864 complement(1947353..1947469) 1 NC_011353.1 identified by glimmer; hypothetical protein 1947469 6970864 ECH74115_2049 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270451.1 1947353 R 444450 CDS YP_002270452.1 209399280 6971671 1947695..1947916 1 NC_011353.1 hypothetical protein 1947916 6971671 ECH74115_2051 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270452.1 1947695 D 444450 CDS YP_002270453.1 209398504 6970396 1948002..1948235 1 NC_011353.1 hypothetical protein 1948235 6970396 ECH74115_2052 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270453.1 1948002 D 444450 CDS YP_002270454.1 209398088 6969562 complement(1948236..1948685) 1 NC_011353.1 identified by match to protein family HMM PF04657; hypothetical protein 1948685 6969562 ECH74115_2053 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270454.1 1948236 R 444450 CDS YP_002270455.1 209397658 6969106 complement(1948682..1949263) 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1949263 6969106 ECH74115_2054 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002270455.1 1948682 R 444450 CDS YP_002270456.1 209396787 6968641 1949381..1950418 1 NC_011353.1 identified by match to protein family HMM PF00107; oxidoreductase, zinc-binding dehydrogenase family 1950418 6968641 ECH74115_2055 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002270456.1 1949381 D 444450 CDS YP_002270457.1 209398301 6967718 1950616..1951281 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; DNA-binding transcriptional regulator 1951281 6967718 ECH74115_2056 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002270457.1 1950616 D 444450 CDS YP_002270458.1 209398339 6969337 complement(1951317..1953419) 1 NC_011353.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor 1953419 6969337 ECH74115_2057 Escherichia coli O157:H7 str. EC4115 TonB-dependent receptor YP_002270458.1 1951317 R 444450 CDS YP_002270459.1 209399084 6969379 1953661..1954722 1 NC_011353.1 hypothetical protein 1954722 6969379 ECH74115_2058 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270459.1 1953661 D 444450 CDS YP_002270460.1 209396771 6970186 complement(1954837..1956336) 1 NC_011353.1 identified by match to protein family HMM PF00324; L-asparagine permease 1956336 ansP 6970186 ansP Escherichia coli O157:H7 str. EC4115 L-asparagine permease YP_002270460.1 1954837 R 444450 CDS YP_002270461.1 209397593 6967700 1956406..1956555 1 NC_011353.1 identified by glimmer; hypothetical protein 1956555 6967700 ECH74115_2060 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270461.1 1956406 D 444450 CDS YP_002270462.1 209396085 6968572 1956603..1957220 1 NC_011353.1 transferase 1957220 6968572 ECH74115_2061 Escherichia coli O157:H7 str. EC4115 transferase YP_002270462.1 1956603 D 444450 CDS YP_002270463.1 209396796 6966964 1957389..1957508 1 NC_011353.1 hypothetical protein 1957508 6966964 ECH74115_2062 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270463.1 1957389 D 444450 CDS YP_002270464.1 209399781 6967728 complement(1957921..1958067) 1 NC_011353.1 identified by glimmer; hypothetical protein 1958067 6967728 ECH74115_2063 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270464.1 1957921 R 444450 CDS YP_002270465.1 209400664 6970938 1958329..1960437 1 NC_011353.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 1960437 6970938 ECH74115_2064 Escherichia coli O157:H7 str. EC4115 ImpA family type VI secretion-associated protein YP_002270465.1 1958329 D 444450 CDS YP_002270466.1 209397644 6971881 1960504..1964706 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsD 1964706 6971881 ECH74115_2065 Escherichia coli O157:H7 str. EC4115 protein rhsD YP_002270466.1 1960504 D 444450 CDS YP_002270467.1 209400152 6972143 1966888..1967115 1 NC_011353.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1967115 6972143 ECH74115_2070 Escherichia coli O157:H7 str. EC4115 4-oxalocrotonate tautomerase YP_002270467.1 1966888 D 444450 CDS YP_002270468.1 209397181 6968953 complement(1968801..1969694) 1 NC_011353.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654; hypothetical protein 1969694 6968953 ECH74115_2074 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270468.1 1968801 R 444450 CDS YP_002270469.1 209400587 6968135 complement(1969773..1970453) 1 NC_011353.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase 2 subunit gamma 1970453 narV 6968135 narV Escherichia coli O157:H7 str. EC4115 respiratory nitrate reductase 2 subunit gamma YP_002270469.1 1969773 R 444450 CDS YP_002270470.1 209400611 6971798 complement(1970450..1971145) 1 NC_011353.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 2 1971145 narW 6971798 narW Escherichia coli O157:H7 str. EC4115 nitrate reductase molybdenum cofactor assembly chaperone 2 YP_002270470.1 1970450 R 444450 CDS YP_002270471.1 209400809 6971823 complement(1971145..1972689) 1 NC_011353.1 identified by match to protein family HMM TIGR01660; nitrate reductase 2 subunit beta 1972689 narY 6971823 narY Escherichia coli O157:H7 str. EC4115 nitrate reductase 2 subunit beta YP_002270471.1 1971145 R 444450 CDS YP_002270472.1 209398888 6972037 complement(1972686..1976426) 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase 2 subunit alpha 1976426 narZ 6972037 narZ Escherichia coli O157:H7 str. EC4115 nitrate reductase 2 subunit alpha YP_002270472.1 1972686 R 444450 CDS YP_002270473.1 209399656 6969977 complement(1976508..1977896) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 2 1977896 narU 6969977 narU Escherichia coli O157:H7 str. EC4115 nitrite extrusion protein 2 YP_002270473.1 1976508 R 444450 CDS YP_002270474.1 209397006 6970802 complement(1978202..1979461) 1 NC_011353.1 leucine-rich repeat protein 1979461 6970802 ECH74115_2080 Escherichia coli O157:H7 str. EC4115 leucine-rich repeat protein YP_002270474.1 1978202 R 444450 CDS YP_002270475.1 209396427 6966731 complement(1980951..1982051) 1 NC_011353.1 identified by match to protein family HMM PF00267; gram-negative porin family protein 1982051 6966731 ECH74115_2083 Escherichia coli O157:H7 str. EC4115 gram-negative porin family protein YP_002270475.1 1980951 R 444450 CDS YP_002270476.1 209398545 6967334 complement(1982310..1983191) 1 NC_011353.1 identified by match to protein family HMM PF00892; hypothetical protein 1983191 6967334 ECH74115_2084 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270476.1 1982310 R 444450 CDS YP_002270477.1 209398136 6969342 1986489..1987367 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 1987367 fdnH 6969342 fdnH Escherichia coli O157:H7 str. EC4115 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_002270477.1 1986489 D 444450 CDS YP_002270478.1 209398691 6969158 1987360..1988013 1 NC_011353.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1988013 fdnI 6969158 fdnI Escherichia coli O157:H7 str. EC4115 formate dehydrogenase-N subunit gamma YP_002270478.1 1987360 D 444450 CDS YP_002270479.1 209399277 6969762 complement(1988241..1988525) 1 NC_011353.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; HigA family addiction module antidote protein 1988525 6969762 ECH74115_2089 Escherichia coli O157:H7 str. EC4115 HigA family addiction module antidote protein YP_002270479.1 1988241 R 444450 CDS YP_002270480.1 209396014 6970393 complement(1988671..1989681) 1 NC_011353.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1989681 6970393 ECH74115_2090 Escherichia coli O157:H7 str. EC4115 alcohol dehydrogenase YP_002270480.1 1988671 R 444450 CDS YP_002270481.1 209396539 6966887 complement(1989815..1991512) 1 NC_011353.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1991512 sfcA 6966887 sfcA Escherichia coli O157:H7 str. EC4115 malate dehydrogenase YP_002270481.1 1989815 R 444450 CDS YP_002270482.1 209397131 6967452 complement(1991669..1991806) 1 NC_011353.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1991806 rpsV 6967452 rpsV Escherichia coli O157:H7 str. EC4115 30S ribosomal subunit S22 YP_002270482.1 1991669 R 444450 CDS YP_002270483.1 209397715 6968080 complement(1991908..1992123) 1 NC_011353.1 biofilm-dependent modulation protein 1992123 6968080 ECH74115_2093 Escherichia coli O157:H7 str. EC4115 biofilm-dependent modulation protein YP_002270483.1 1991908 R 444450 CDS YP_002270484.1 209398412 6968700 1992468..1992899 1 NC_011353.1 identified by match to protein family HMM PF02566; match to protein family HMM TIGR03562; peroxiredoxin OsmC 1992899 osmC 6968700 osmC Escherichia coli O157:H7 str. EC4115 peroxiredoxin OsmC YP_002270484.1 1992468 D 444450 CDS YP_002270485.1 209397883 6969459 complement(1992955..1993881) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1993881 6969459 ECH74115_2095 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002270485.1 1992955 R 444450 CDS YP_002270486.1 209396279 6968880 complement(1993874..1994860) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1994860 6968880 ECH74115_2096 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002270486.1 1993874 R 444450 CDS YP_002270487.1 209398033 6967173 complement(1994857..1995753) 1 NC_011353.1 identified by match to protein family HMM PF00528; ATP-dependent peptide transporter membrane subunit 1995753 yddQ 6967173 yddQ Escherichia coli O157:H7 str. EC4115 ATP-dependent peptide transporter membrane subunit YP_002270487.1 1994857 R 444450 CDS YP_002270488.1 209399112 6969046 complement(1995750..1996772) 1 NC_011353.1 identified by match to protein family HMM PF00528; inner membrane ABC transporter permease yddR 1996772 yddR 6969046 yddR Escherichia coli O157:H7 str. EC4115 inner membrane ABC transporter permease yddR YP_002270488.1 1995750 R 444450 CDS YP_002270489.1 209398371 6970214 complement(1996774..1998324) 1 NC_011353.1 identified by match to protein family HMM PF00496; ABC transporter periplasmic-binding protein yddS precursor 1998324 6970214 ECH74115_2099 Escherichia coli O157:H7 str. EC4115 ABC transporter periplasmic-binding protein yddS precursor YP_002270489.1 1996774 R 444450 CDS YP_002270490.1 209400569 6969414 complement(1998338..1998919) 1 NC_011353.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 1998919 ddpX 6969414 ddpX Escherichia coli O157:H7 str. EC4115 D-alanyl-D-alanine dipeptidase YP_002270490.1 1998338 R 444450 CDS YP_002270491.1 209396130 6967635 complement(2001591..2002973) 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2002973 6967635 ECH74115_2103 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002270491.1 2001591 R 444450 CDS YP_002270492.1 209396682 6967012 complement(2003350..2004564) 1 NC_011353.1 identified by match to protein family HMM PF02638; lipoprotein 2004564 6967012 ECH74115_2104 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270492.1 2003350 R 444450 CDS YP_002270493.1 209396109 6967603 complement(2004800..2006335) 1 NC_011353.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910; glutamate:gamma aminobutyrate antiporter 2006335 gadC 6967603 gadC Escherichia coli O157:H7 str. EC4115 glutamate:gamma aminobutyrate antiporter YP_002270493.1 2004800 R 444450 CDS YP_002270494.1 209399389 6966988 complement(2006491..2007891) 1 NC_011353.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase 2007891 gadA 6966988 gadA Escherichia coli O157:H7 str. EC4115 glutamate decarboxylase YP_002270494.1 2006491 R 444450 CDS YP_002270495.1 209398793 6970514 complement(2008252..2011035) 1 NC_011353.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16B family 2011035 pqqL 6970514 pqqL Escherichia coli O157:H7 str. EC4115 peptidase, M16B family YP_002270495.1 2008252 R 444450 CDS YP_002270496.1 209397189 6969872 complement(2011092..2013464) 1 NC_011353.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor 2013464 6969872 ECH74115_2108 Escherichia coli O157:H7 str. EC4115 TonB-dependent receptor YP_002270496.1 2011092 R 444450 CDS YP_002270497.1 209399273 6968145 complement(2013502..2015187) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF05992; match to protein family HMM PF06472; inner membrane ABC transporter ATP-binding protein 2015187 6968145 ECH74115_2109 Escherichia coli O157:H7 str. EC4115 inner membrane ABC transporter ATP-binding protein YP_002270497.1 2013502 R 444450 CDS YP_002270498.1 209397007 6970389 complement(2015478..2016635) 1 NC_011353.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 2016635 6970389 ECH74115_2110 Escherichia coli O157:H7 str. EC4115 radical SAM domain-containing protein YP_002270498.1 2015478 R 444450 CDS YP_002270499.1 209396156 6967641 complement(2018773..2019534) 1 NC_011353.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 2019534 6967641 ECH74115_2112 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YdeO YP_002270499.1 2018773 R 444450 CDS YP_002270500.1 209400612 6967039 complement(2019608..2019790) 1 NC_011353.1 hypothetical protein 2019790 6967039 ECH74115_2113 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270500.1 2019608 R 444450 CDS YP_002270501.1 209400692 6971824 complement(2020053..2022332) 1 NC_011353.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase 2022332 6971824 ECH74115_2114 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002270501.1 2020053 R 444450 CDS YP_002270502.1 209396169 6971913 complement(2022666..2023580) 1 NC_011353.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160; FimH-like protein 2023580 6971913 ECH74115_2115 Escherichia coli O157:H7 str. EC4115 FimH-like protein YP_002270502.1 2022666 R 444450 CDS YP_002270503.1 209400755 6967053 complement(2023640..2023930) 1 NC_011353.1 FimG-like protein 2023930 6967053 ECH74115_2116 Escherichia coli O157:H7 str. EC4115 FimG-like protein YP_002270503.1 2023640 R 444450 CDS YP_002270504.1 209397662 6971980 complement(2024156..2024686) 1 NC_011353.1 identified by match to protein family HMM PF00419; FimF-like protein 2024686 6971980 ECH74115_2117 Escherichia coli O157:H7 str. EC4115 FimF-like protein YP_002270504.1 2024156 R 444450 CDS YP_002270505.1 209396439 6968645 complement(2024700..2026922) 1 NC_011353.1 identified by match to protein family HMM PF00577; fimbrial usher family protein 2026922 6968645 ECH74115_2118 Escherichia coli O157:H7 str. EC4115 fimbrial usher family protein YP_002270505.1 2024700 R 444450 CDS YP_002270506.1 209399101 6967349 complement(2027393..2028103) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 2028103 6967349 ECH74115_2119 Escherichia coli O157:H7 str. EC4115 periplasmic pilus chaperone family protein YP_002270506.1 2027393 R 444450 CDS YP_002270507.1 209398354 6970203 complement(2028464..2029027) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 2029027 6970203 ECH74115_2120 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002270507.1 2028464 R 444450 CDS YP_002270508.1 209400663 6969395 complement(2030001..2031056) 1 NC_011353.1 identified by match to protein family HMM PF07804; match to protein family HMM PF07805; protein HipA 2031056 6969395 ECH74115_2121 Escherichia coli O157:H7 str. EC4115 protein HipA YP_002270508.1 2030001 R 444450 CDS YP_002270509.1 209400988 6971060 complement(2032578..2036471) 1 NC_011353.1 identified by glimmer; lipoprotein 2036471 6971060 ECH74115_2123 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270509.1 2032578 R 444450 CDS YP_002270510.1 209400212 6972230 complement(2037140..2038732) 1 NC_011353.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; autoinducer-2 (AI-2) kinase 2038732 lsrK 6972230 lsrK Escherichia coli O157:H7 str. EC4115 autoinducer-2 (AI-2) kinase YP_002270510.1 2037140 R 444450 CDS YP_002270511.1 209397971 6971400 complement(2038811..2039764) 1 NC_011353.1 identified by match to protein family HMM PF04198; transcriptional repressor LsrR 2039764 lsrR 6971400 lsrR Escherichia coli O157:H7 str. EC4115 transcriptional repressor LsrR YP_002270511.1 2038811 R 444450 CDS YP_002270512.1 209395735 6968979 2040013..2041548 1 NC_011353.1 identified by match to protein family HMM PF00005; autoinducer-2 ABC transporter ATP-binding protein LsrA 2041548 lsrA 6968979 lsrA Escherichia coli O157:H7 str. EC4115 autoinducer-2 ABC transporter ATP-binding protein LsrA YP_002270512.1 2040013 D 444450 CDS YP_002270513.1 209398891 6966590 2041542..2042570 1 NC_011353.1 identified by match to protein family HMM PF02653; autoinducer-2 ABC transporter permease LsrC 2042570 lsrC 6966590 lsrC Escherichia coli O157:H7 str. EC4115 autoinducer-2 ABC transporter permease LsrC YP_002270513.1 2041542 D 444450 CDS YP_002270514.1 209399642 6969980 2042570..2043562 1 NC_011353.1 identified by match to protein family HMM PF02653; autoinducer-2 ABC transporter permease LsrD 2043562 lsrD 6969980 lsrD Escherichia coli O157:H7 str. EC4115 autoinducer-2 ABC transporter permease LsrD YP_002270514.1 2042570 D 444450 CDS YP_002270515.1 209400955 6970787 2043574..2044596 1 NC_011353.1 autoinducer-2 ABC transporter periplasmic autoinducer-2-binding protein LsrB 2044596 lsrB 6970787 lsrB Escherichia coli O157:H7 str. EC4115 autoinducer-2 ABC transporter periplasmic autoinducer-2-binding protein LsrB YP_002270515.1 2043574 D 444450 CDS YP_002270516.1 209398692 6972193 2044623..2045498 1 NC_011353.1 identified by match to protein family HMM PF01791; aldolase 2045498 lsrF 6972193 lsrF Escherichia coli O157:H7 str. EC4115 aldolase YP_002270516.1 2044623 D 444450 CDS YP_002270517.1 209396806 6969764 2045522..2045812 1 NC_011353.1 identified by match to protein family HMM PF03992; autoinducer-2 (AI-2) modifying protein LsrG 2045812 lsrG 6969764 lsrG Escherichia coli O157:H7 str. EC4115 autoinducer-2 (AI-2) modifying protein LsrG YP_002270517.1 2045522 D 444450 CDS YP_002270518.1 209399847 6967738 2045869..2046627 1 NC_011353.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 2046627 tam 6967738 tam Escherichia coli O157:H7 str. EC4115 trans-aconitate 2-methyltransferase YP_002270518.1 2045869 D 444450 CDS YP_002270519.1 209395864 6971004 complement(2046631..2047545) 1 NC_011353.1 identified by match to protein family HMM PF05249; hypothetical protein 2047545 6971004 ECH74115_2133 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270519.1 2046631 R 444450 CDS YP_002270520.1 209396611 6966726 complement(2047742..2049193) 1 NC_011353.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 2049193 uxaB 6966726 uxaB Escherichia coli O157:H7 str. EC4115 altronate oxidoreductase YP_002270520.1 2047742 R 444450 CDS YP_002270521.1 209396620 6967530 complement(2049420..2050838) 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2050838 6967530 ECH74115_2135 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002270521.1 2049420 R 444450 CDS YP_002270522.1 209395871 6967539 complement(2050977..2051336) 1 NC_011353.1 hypothetical protein 2051336 6967539 ECH74115_2136 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270522.1 2050977 R 444450 CDS YP_002270523.1 209397814 6966735 complement(2051336..2052262) 1 NC_011353.1 catalyzes the formation of glutamate from glutamine; glutaminase 2052262 glsA2 6966735 glsA2 Escherichia coli O157:H7 str. EC4115 glutaminase YP_002270523.1 2051336 R 444450 CDS YP_002270524.1 209397066 6968805 complement(2052326..2053714) 1 NC_011353.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 2053714 6968805 ECH74115_2138 Escherichia coli O157:H7 str. EC4115 succinate semialdehyde dehydrogenase YP_002270524.1 2052326 R 444450 CDS YP_002270525.1 209399635 6968012 2053815..2054696 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2054696 6968012 ECH74115_2139 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002270525.1 2053815 D 444450 CDS YP_002270526.1 209400312 6971914 2056040..2057230 1 NC_011353.1 identified by match to protein family HMM PF07690; sugar efflux transporter 2057230 sotB 6971914 sotB Escherichia coli O157:H7 str. EC4115 sugar efflux transporter YP_002270526.1 2056040 D 444450 CDS YP_002270527.1 209396173 6971507 complement(2057255..2057920) 1 NC_011353.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 2057920 marC 6971507 marC Escherichia coli O157:H7 str. EC4115 multiple drug resistance protein MarC YP_002270527.1 2057255 R 444450 CDS YP_002270528.1 209400719 6967059 2058132..2058566 1 NC_011353.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 2058566 marR 6967059 marR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor MarR YP_002270528.1 2058132 D 444450 CDS YP_002270529.1 209396838 6971943 2058586..2058969 1 NC_011353.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 2058969 marA 6971943 marA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator MarA YP_002270529.1 2058586 D 444450 CDS YP_002270530.1 209396282 6967771 2059001..2059219 1 NC_011353.1 hypothetical protein 2059219 marB 6967771 marB Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270530.1 2059001 D 444450 CDS YP_002270531.1 209399968 6967176 complement(2059250..2060149) 1 NC_011353.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151; O-acetylserine/cysteine export protein 2060149 eamA 6967176 eamA Escherichia coli O157:H7 str. EC4115 O-acetylserine/cysteine export protein YP_002270531.1 2059250 R 444450 CDS YP_002270532.1 209398928 6971139 2060344..2061531 1 NC_011353.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 2061531 6971139 ECH74115_2148 Escherichia coli O157:H7 str. EC4115 MFS-type transporter YdeE YP_002270532.1 2060344 D 444450 CDS YP_002270533.1 209400506 6970021 complement(2061572..2061967) 1 NC_011353.1 rhodanese domain-containing protein 2061967 6970021 ECH74115_2149 Escherichia coli O157:H7 str. EC4115 rhodanese domain-containing protein YP_002270533.1 2061572 R 444450 CDS YP_002270534.1 209397563 6971711 2062041..2063033 1 NC_011353.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrA 2063033 ftrA 6971711 ftrA Escherichia coli O157:H7 str. EC4115 transcriptional activator FtrA YP_002270534.1 2062041 D 444450 CDS YP_002270535.1 209399358 6968539 complement(2063455..2064345) 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein 2064345 6968539 ECH74115_2151 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270535.1 2063455 R 444450 CDS YP_002270536.1 209397734 6970480 complement(2064600..2064992) 1 NC_011353.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein 2064992 6970480 ECH74115_2152 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270536.1 2064600 R 444450 CDS YP_002270537.1 209397167 6968719 2065268..2065786 1 NC_011353.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A 2065786 6968719 ECH74115_2153 Escherichia coli O157:H7 str. EC4115 competence damage-inducible protein A YP_002270537.1 2065268 D 444450 CDS YP_002270538.1 209396978 6968120 complement(2065831..2067876) 1 NC_011353.1 identified by match to protein family HMM PF01432; dipeptidyl carboxypeptidase II 2067876 dcp 6968120 dcp Escherichia coli O157:H7 str. EC4115 dipeptidyl carboxypeptidase II YP_002270538.1 2065831 R 444450 CDS YP_002270539.1 209396253 6967919 2068013..2068759 1 NC_011353.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 2068759 6967919 ECH74115_2155 Escherichia coli O157:H7 str. EC4115 3-hydroxy acid dehydrogenase YP_002270539.1 2068013 D 444450 CDS YP_002270540.1 209398140 6967146 2068848..2069534 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 2069534 6967146 ECH74115_2156 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002270540.1 2068848 D 444450 CDS YP_002270541.1 209397360 6969162 2069711..2069914 1 NC_011353.1 identified by match to protein family HMM TIGR03318; hypothetical protein 2069914 6969162 ECH74115_2157 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270541.1 2069711 D 444450 CDS YP_002270542.1 209399925 6968327 complement(2069950..2071410) 1 NC_011353.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase family protein 2071410 6968327 ECH74115_2158 Escherichia coli O157:H7 str. EC4115 mannitol dehydrogenase family protein YP_002270542.1 2069950 R 444450 CDS YP_002270543.1 209399099 6971089 complement(2071499..2072782) 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; inner membrane metabolite transport protein ydfJ 2072782 ydfJ 6971089 ydfJ Escherichia coli O157:H7 str. EC4115 inner membrane metabolite transport protein ydfJ YP_002270543.1 2071499 R 444450 CDS YP_002270544.1 209395736 6970201 2072950..2073156 1 NC_011353.1 identified by match to protein family HMM PF06183; hypothetical protein 2073156 6970201 ECH74115_2160 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270544.1 2072950 D 444450 CDS YP_002270545.1 209400958 6966591 complement(2073318..2073959) 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 2073959 6966591 ECH74115_2161 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270545.1 2073318 R 444450 CDS YP_002270546.1 209397140 6972196 complement(2074041..2074442) 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 2074442 6972196 ECH74115_2162 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270546.1 2074041 R 444450 CDS YP_002270547.1 209396587 6968091 complement(2074743..2075078) 1 NC_011353.1 identified by match to protein family HMM PF06416; non-LEE-encoded effector NleG 2075078 6968091 ECH74115_2163 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector NleG YP_002270547.1 2074743 R 444450 CDS YP_002270548.1 209399523 6967502 complement(2075432..2075701) 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 2075701 6967502 ECH74115_2164 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002270548.1 2075432 R 444450 CDS YP_002270549.1 209398870 6970659 complement(2075703..2077016) 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 2077016 6970659 ECH74115_2165 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002270549.1 2075703 R 444450 CDS YP_002270550.1 209397041 6969956 complement(2077081..2077680) 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 2077680 6969956 ECH74115_2166 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002270550.1 2077081 R 444450 CDS YP_002270551.1 209399271 6967986 complement(2077748..2080261) 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 2080261 6967986 ECH74115_2167 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270551.1 2077748 R 444450 CDS YP_002270552.1 209395902 6970387 complement(2080258..2081826) 1 NC_011353.1 host specificity protein 2081826 6970387 ECH74115_2168 Escherichia coli O157:H7 str. EC4115 host specificity protein YP_002270552.1 2080258 R 444450 CDS YP_002270553.1 209398117 6966768 complement(2082168..2082749) 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 2082749 6966768 ECH74115_2169 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002270553.1 2082168 R 444450 CDS YP_002270554.1 209400139 6969136 complement(2082746..2083489) 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 2083489 6969136 ECH74115_2170 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002270554.1 2082746 R 444450 CDS YP_002270555.1 209396866 6971325 complement(2083500..2084198) 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 2084198 6971325 ECH74115_2171 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002270555.1 2083500 R 444450 CDS YP_002270556.1 209398914 6967801 complement(2084198..2084539) 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 2084539 6967801 ECH74115_2172 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002270556.1 2084198 R 444450 CDS YP_002270557.1 209397200 6970006 complement(2084532..2087774) 1 NC_011353.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein 2087774 6970006 ECH74115_2173 Escherichia coli O157:H7 str. EC4115 tail length tape measure protein YP_002270557.1 2084532 R 444450 CDS YP_002270558.1 209398287 6968156 complement(2087826..2088029) 1 NC_011353.1 identified by glimmer; hypothetical protein 2088029 6968156 ECH74115_2174 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270558.1 2087826 R 444450 CDS YP_002270559.1 209397560 6969321 complement(2088131..2088505) 1 NC_011353.1 identified by match to protein family HMM PF06222; phage tail assembly chaperone 2088505 6969321 ECH74115_2175 Escherichia coli O157:H7 str. EC4115 phage tail assembly chaperone YP_002270559.1 2088131 R 444450 CDS YP_002270560.1 209395835 6968536 complement(2088511..2089227) 1 NC_011353.1 identified by match to protein family HMM PF07679; major tail protein 2089227 6968536 ECH74115_2176 Escherichia coli O157:H7 str. EC4115 major tail protein YP_002270560.1 2088511 R 444450 CDS YP_002270561.1 209400575 6966692 complement(2089286..2089630) 1 NC_011353.1 identified by glimmer; hypothetical protein 2089630 6966692 ECH74115_2177 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270561.1 2089286 R 444450 CDS YP_002270562.1 209399198 6971785 complement(2089627..2090073) 1 NC_011353.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 2090073 6971785 ECH74115_2178 Escherichia coli O157:H7 str. EC4115 phage protein, HK97 gp10 family YP_002270562.1 2089627 R 444450 CDS YP_002270563.1 209398623 6970306 complement(2090070..2090420) 1 NC_011353.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor 2090420 6970306 ECH74115_2179 Escherichia coli O157:H7 str. EC4115 phage head-tail adaptor YP_002270563.1 2090070 R 444450 CDS YP_002270564.1 209398720 6969686 complement(2090430..2090756) 1 NC_011353.1 hypothetical protein 2090756 6969686 ECH74115_2180 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270564.1 2090430 R 444450 CDS YP_002270565.1 209396297 6967807 complement(2092797..2093018) 1 NC_011353.1 hypothetical protein 2093018 6967807 ECH74115_2183 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270565.1 2092797 R 444450 CDS YP_002270566.1 209397328 6967192 complement(2093063..2093596) 1 NC_011353.1 peptidase U35, phage prohead HK97 2093596 6967192 ECH74115_2184 Escherichia coli O157:H7 str. EC4115 peptidase U35, phage prohead HK97 YP_002270566.1 2093063 R 444450 CDS YP_002270567.1 209396654 6968292 complement(2093562..2093969) 1 NC_011353.1 identified by match to protein family HMM PF07041; hypothetical protein 2093969 6968292 ECH74115_2185 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270567.1 2093562 R 444450 CDS YP_002270568.1 209400890 6967574 complement(2093974..2094180) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 2094180 6967574 ECH74115_2186 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270568.1 2093974 R 444450 CDS YP_002270569.1 209400057 6972124 2094188..2094349 1 NC_011353.1 hypothetical protein 2094349 6972124 ECH74115_2187 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270569.1 2094188 D 444450 CDS YP_002270570.1 209399696 6971236 complement(2094628..2096478) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 2096478 6971236 ECH74115_2188 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270570.1 2094628 R 444450 CDS YP_002270571.1 209397782 6969967 complement(2096792..2096959) 1 NC_011353.1 hypothetical protein 2096959 6969967 ECH74115_2190 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270571.1 2096792 R 444450 CDS YP_002270572.1 209397019 6968770 complement(2096956..2097387) 1 NC_011353.1 protein TerB 2097387 6968770 ECH74115_2191 Escherichia coli O157:H7 str. EC4115 protein TerB YP_002270572.1 2096956 R 444450 CDS YP_002270573.1 209396616 6972386 complement(2097838..2098425) 1 NC_011353.1 identified by match to protein family HMM PF00165; transcriptional regulator 2098425 6972386 ECH74115_2194 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002270573.1 2097838 R 444450 CDS YP_002270574.1 209395946 6967535 2098442..2098582 1 NC_011353.1 identified by glimmer; hypothetical protein 2098582 6967535 ECH74115_2195 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270574.1 2098442 D 444450 CDS YP_002270575.1 209396008 6966813 complement(2098687..2099007) 1 NC_011353.1 hypothetical protein 2099007 6966813 ECH74115_2196 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270575.1 2098687 R 444450 CDS YP_002270576.1 209396537 6966880 complement(2099109..2099663) 1 NC_011353.1 identified by match to protein family HMM PF06576; anti-terminator protein 2099663 6966880 ECH74115_2197 Escherichia coli O157:H7 str. EC4115 anti-terminator protein YP_002270576.1 2099109 R 444450 CDS YP_002270577.1 209397705 6968130 complement(2100044..2101093) 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 2101093 6968130 ECH74115_2199 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270577.1 2100044 R 444450 CDS YP_002270578.1 209399004 6968689 complement(2101095..2101367) 1 NC_011353.1 hypothetical protein 2101367 6968689 ECH74115_2200 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270578.1 2101095 R 444450 CDS YP_002270579.1 209399393 6970103 complement(2101489..2101833) 1 NC_011353.1 identified by match to protein family HMM PF01336; match to protein family HMM PF04076; protein YgiW 2101833 6970103 ECH74115_2201 Escherichia coli O157:H7 str. EC4115 protein YgiW YP_002270579.1 2101489 R 444450 CDS YP_002270580.1 209400422 6970518 complement(2102399..2102956) 1 NC_011353.1 identified by match to protein family HMM PF04448; hypothetical protein 2102956 6970518 ECH74115_2202 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270580.1 2102399 R 444450 CDS YP_002270581.1 209400855 6971624 complement(2102958..2103176) 1 NC_011353.1 hypothetical protein 2103176 6971624 ECH74115_2203 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270581.1 2102958 R 444450 CDS YP_002270582.1 209396530 6972086 complement(2103304..2103615) 1 NC_011353.1 hypothetical protein 2103615 6972086 ECH74115_2204 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270582.1 2103304 R 444450 CDS YP_002270583.1 209397068 6967443 complement(2103608..2103835) 1 NC_011353.1 hypothetical protein 2103835 6967443 ECH74115_2205 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270583.1 2103608 R 444450 CDS YP_002270584.1 209395717 6968014 complement(2103832..2104086) 1 NC_011353.1 hypothetical protein 2104086 6968014 ECH74115_2206 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270584.1 2103832 R 444450 CDS YP_002270585.1 209396432 6966572 complement(2104146..2104862) 1 NC_011353.1 identified by match to protein family HMM PF07789; hypothetical protein 2104862 6966572 ECH74115_2207 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270585.1 2104146 R 444450 CDS YP_002270586.1 209398151 6967340 complement(2104896..2105357) 1 NC_011353.1 hypothetical protein 2105357 6967340 ECH74115_2208 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270586.1 2104896 R 444450 CDS YP_002270587.1 209398826 6969174 complement(2105350..2106393) 1 NC_011353.1 hypothetical protein 2106393 6969174 ECH74115_2209 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270587.1 2105350 R 444450 CDS YP_002270588.1 209399412 6969909 complement(2106462..2106860) 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 2106860 6969909 ECH74115_2210 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270588.1 2106462 R 444450 CDS YP_002270589.1 209400263 6970538 2107205..2107843 1 NC_011353.1 identified by match to protein family HMM PF00717; repressor protein encoded within prophage CP-933O 2107843 6970538 ECH74115_2211 Escherichia coli O157:H7 str. EC4115 repressor protein encoded within prophage CP-933O YP_002270589.1 2107205 D 444450 CDS YP_002270590.1 209400916 6971456 2108055..2108288 1 NC_011353.1 identified by match to protein family HMM PF07151; hypothetical protein 2108288 6971456 ECH74115_2212 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270590.1 2108055 D 444450 CDS YP_002270591.1 209395710 6972152 2108300..2108938 1 NC_011353.1 identified by glimmer; hypothetical protein 2108938 6972152 ECH74115_2213 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270591.1 2108300 D 444450 CDS YP_002270592.1 209396638 6966564 complement(2108939..2109148) 1 NC_011353.1 identified by glimmer; hypothetical protein 2109148 6966564 ECH74115_2214 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270592.1 2108939 R 444450 CDS YP_002270593.1 209397191 6967558 complement(2109447..2109602) 1 NC_011353.1 identified by glimmer; hypothetical protein 2109602 6967558 ECH74115_2215 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270593.1 2109447 R 444450 CDS YP_002270594.1 209396301 6970867 2109713..2109901 1 NC_011353.1 hypothetical protein 2109901 6970867 ECH74115_2217 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270594.1 2109713 D 444450 CDS YP_002270595.1 209395829 6967196 2109898..2110086 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 2110086 6967196 ECH74115_2218 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270595.1 2109898 D 444450 CDS YP_002270596.1 209398561 6968987 2112165..2112371 1 NC_011353.1 identified by match to protein family HMM PF06183; hypothetical protein 2112371 6968987 ECH74115_2221 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270596.1 2112165 D 444450 CDS YP_002270597.1 209399234 6969621 complement(2112421..2113290) 1 NC_011353.1 identified by match to protein family HMM PF00872; mutator family transposase 2113290 6969621 ECH74115_2222 Escherichia coli O157:H7 str. EC4115 mutator family transposase YP_002270597.1 2112421 R 444450 CDS YP_002270598.1 209399755 6970345 2113711..2114058 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 2114058 6970345 ECH74115_2223 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002270598.1 2113711 D 444450 CDS YP_002270599.1 209400332 6970911 2114108..2115646 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 2115646 6970911 ECH74115_2224 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002270599.1 2114108 D 444450 CDS YP_002270600.1 209396944 6971529 complement(2115657..2116079) 1 NC_011353.1 transposase 2116079 6971529 ECH74115_2225 Escherichia coli O157:H7 str. EC4115 transposase YP_002270600.1 2115657 R 444450 CDS YP_002270601.1 209399261 6967882 complement(2116229..2116879) 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 2116879 6967882 ECH74115_2226 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270601.1 2116229 R 444450 CDS YP_002270602.1 209397346 6970377 complement(2117153..2117299) 1 NC_011353.1 hypothetical protein 2117299 6970377 ECH74115_2227 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270602.1 2117153 R 444450 CDS YP_002270603.1 209398174 6968313 complement(2117590..2118165) 1 NC_011353.1 identified by match to protein family HMM PF06416; non-LEE-encoded effector NleG 2118165 6968313 ECH74115_2228 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector NleG YP_002270603.1 2117590 R 444450 CDS YP_002270604.1 209396259 6969199 complement(2118279..2118548) 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 2118548 6969199 ECH74115_2229 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002270604.1 2118279 R 444450 CDS YP_002270605.1 209399699 6967152 complement(2118550..2119773) 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 2119773 6967152 ECH74115_2230 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002270605.1 2118550 R 444450 CDS YP_002270606.1 209400355 6970849 complement(2119838..2120437) 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 2120437 6970849 ECH74115_2231 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002270606.1 2119838 R 444450 CDS YP_002270607.1 209397318 6970322 complement(2124050..2124193) 1 NC_011353.1 identified by glimmer; hypothetical protein 2124193 6970322 ECH74115_2234 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270607.1 2124050 R 444450 CDS YP_002270608.1 209398138 6968280 complement(2124171..2124608) 1 NC_011353.1 identified by match to protein family HMM TIGR01600; minor tail protein 2124608 6968280 ECH74115_2235 Escherichia coli O157:H7 str. EC4115 minor tail protein YP_002270608.1 2124171 R 444450 CDS YP_002270609.1 209398059 6969160 complement(2124608..2124949) 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 2124949 6969160 ECH74115_2236 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002270609.1 2124608 R 444450 CDS YP_002270610.1 209397501 6969074 complement(2124942..2128184) 1 NC_011353.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein 2128184 6969074 ECH74115_2237 Escherichia coli O157:H7 str. EC4115 tail length tape measure protein YP_002270610.1 2124942 R 444450 CDS YP_002270611.1 209398444 6968473 complement(2128232..2128435) 1 NC_011353.1 identified by glimmer; hypothetical protein 2128435 6968473 ECH74115_2238 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270611.1 2128232 R 444450 CDS YP_002270612.1 209400544 6969496 complement(2128537..2128911) 1 NC_011353.1 identified by match to protein family HMM PF06222; phage tail assembly chaperone 2128911 6969496 ECH74115_2239 Escherichia coli O157:H7 str. EC4115 phage tail assembly chaperone YP_002270612.1 2128537 R 444450 CDS YP_002270613.1 209396343 6971452 complement(2129708..2130052) 1 NC_011353.1 identified by glimmer; hypothetical protein 2130052 6971452 ECH74115_2241 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270613.1 2129708 R 444450 CDS YP_002270614.1 209396154 6967245 complement(2130049..2130495) 1 NC_011353.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 2130495 6967245 ECH74115_2242 Escherichia coli O157:H7 str. EC4115 phage protein, HK97 gp10 family YP_002270614.1 2130049 R 444450 CDS YP_002270615.1 209398222 6967037 complement(2130492..2130842) 1 NC_011353.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor 2130842 6967037 ECH74115_2243 Escherichia coli O157:H7 str. EC4115 phage head-tail adaptor YP_002270615.1 2130492 R 444450 CDS YP_002270616.1 209399241 6969251 complement(2130852..2131178) 1 NC_011353.1 hypothetical protein 2131178 6969251 ECH74115_2244 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270616.1 2130852 R 444450 CDS YP_002270617.1 209399350 6970353 complement(2131181..2133760) 1 NC_011353.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 2133760 6970353 ECH74115_2245 Escherichia coli O157:H7 str. EC4115 phage portal protein, HK97 family YP_002270617.1 2131181 R 444450 CDS YP_002270618.1 209397565 6970471 complement(2133972..2135909) 1 NC_011353.1 identified by match to protein family HMM PF04586; prohead protease 2135909 6970471 ECH74115_2246 Escherichia coli O157:H7 str. EC4115 prohead protease YP_002270618.1 2133972 R 444450 CDS YP_002270619.1 209398334 6968541 complement(2135973..2137634) 1 NC_011353.1 identified by match to protein family HMM PF03354; phage terminase, large subunit 2137634 6968541 ECH74115_2247 Escherichia coli O157:H7 str. EC4115 phage terminase, large subunit YP_002270619.1 2135973 R 444450 CDS YP_002270620.1 209398486 6969374 complement(2137631..2138194) 1 NC_011353.1 terminase small subunit 2138194 6969374 ECH74115_2248 Escherichia coli O157:H7 str. EC4115 terminase small subunit YP_002270620.1 2137631 R 444450 CDS YP_002270621.1 209400253 6969543 complement(2138486..2138851) 1 NC_011353.1 identified by match to protein family HMM PF01844; HNH endonuclease 2138851 6969543 ECH74115_2249 Escherichia coli O157:H7 str. EC4115 HNH endonuclease YP_002270621.1 2138486 R 444450 CDS YP_002270622.1 209399936 6971444 2138953..2139120 1 NC_011353.1 hypothetical protein 2139120 6971444 ECH74115_2250 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270622.1 2138953 D 444450 CDS YP_002270623.1 209400397 6971101 complement(2139483..2139950) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 2139950 6971101 ECH74115_2251 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002270623.1 2139483 R 444450 CDS YP_002270624.1 209396485 6971598 complement(2139988..2140104) 1 NC_011353.1 hypothetical protein 2140104 6971598 ECH74115_2252 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270624.1 2139988 R 444450 CDS YP_002270625.1 209397159 6967397 complement(2140104..2140673) 1 NC_011353.1 anti-repressor protein Ant 2140673 6967397 ECH74115_2253 Escherichia coli O157:H7 str. EC4115 anti-repressor protein Ant YP_002270625.1 2140104 R 444450 CDS YP_002270626.1 209398091 6968111 complement(2140944..2141477) 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 2141477 6968111 ECH74115_2254 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002270626.1 2140944 R 444450 CDS YP_002270627.1 209398978 6969109 complement(2141528..2141872) 1 NC_011353.1 identified by match to protein family HMM PF07041; hypothetical protein 2141872 6969109 ECH74115_2255 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270627.1 2141528 R 444450 CDS YP_002270628.1 209400760 6970077 complement(2141877..2142083) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 2142083 6970077 ECH74115_2256 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270628.1 2141877 R 444450 CDS YP_002270629.1 209399622 6967239 complement(2142532..2144382) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 2144382 6967239 ECH74115_2258 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270629.1 2142532 R 444450 CDS YP_002270630.1 209397694 6971570 complement(2144697..2144864) 1 NC_011353.1 hypothetical protein 2144864 6971570 ECH74115_2260 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270630.1 2144697 R 444450 CDS YP_002270631.1 209396619 6972427 complement(2145774..2145896) 1 NC_011353.1 identified by glimmer; hypothetical protein 2145896 6972427 ECH74115_2265 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270631.1 2145774 R 444450 CDS YP_002270632.1 209397345 6967538 complement(2145927..2146616) 1 NC_011353.1 identified by match to protein family HMM PF06323; antitermination protein Q 2146616 6967538 ECH74115_2266 Escherichia coli O157:H7 str. EC4115 antitermination protein Q YP_002270632.1 2145927 R 444450 CDS YP_002270633.1 209400068 6968312 complement(2146613..2146972) 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease 2146972 6968312 ECH74115_2267 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease YP_002270633.1 2146613 R 444450 CDS YP_002270634.1 209400833 6971247 complement(2146985..2148034) 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 2148034 6971247 ECH74115_2268 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270634.1 2146985 R 444450 CDS YP_002270635.1 209399617 6969520 complement(2148883..2149032) 1 NC_011353.1 hypothetical protein 2149032 6969520 ECH74115_2270 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270635.1 2148883 R 444450 CDS YP_002270636.1 209396767 6970761 complement(2149103..2149687) 1 NC_011353.1 identified by match to protein family HMM PF04448; hypothetical protein 2149687 6970761 ECH74115_2271 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270636.1 2149103 R 444450 CDS YP_002270637.1 209397405 6967696 complement(2149744..2150139) 1 NC_011353.1 identified by match to protein family HMM PF06163; hypothetical protein 2150139 6967696 ECH74115_2272 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270637.1 2149744 R 444450 CDS YP_002270638.1 209399231 6971717 complement(2150950..2151690) 1 NC_011353.1 identified by match to protein family HMM PF01695; replication protein 2151690 6971717 ECH74115_2275 Escherichia coli O157:H7 str. EC4115 replication protein YP_002270638.1 2150950 R 444450 CDS YP_002270639.1 209399801 6970342 complement(2151697..2152584) 1 NC_011353.1 phage O protein 2152584 6970342 ECH74115_2276 Escherichia coli O157:H7 str. EC4115 phage O protein YP_002270639.1 2151697 R 444450 CDS YP_002270640.1 209397730 6970958 complement(2152682..2153107) 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 2153107 6970958 ECH74115_2277 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270640.1 2152682 R 444450 CDS YP_002270641.1 209398406 6968715 2153657..2153875 1 NC_011353.1 hypothetical protein 2153875 6968715 ECH74115_2278 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270641.1 2153657 D 444450 CDS YP_002270642.1 209398658 6969452 2153860..2154087 1 NC_011353.1 hypothetical protein 2154087 6969452 ECH74115_2279 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270642.1 2153860 D 444450 CDS YP_002270643.1 209398747 6969728 2155091..2155309 1 NC_011353.1 identified by glimmer; hypothetical protein 2155309 6969728 ECH74115_2280 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270643.1 2155091 D 444450 CDS YP_002270644.1 209397970 6969823 complement(2155679..2155849) 1 NC_011353.1 hypothetical protein 2155849 6969823 ECH74115_2281 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270644.1 2155679 R 444450 CDS YP_002270645.1 209397214 6968977 2155878..2156066 1 NC_011353.1 identified by match to protein family HMM PF05358; division inhibition protein DicB 2156066 dicB 6968977 dicB Escherichia coli O157:H7 str. EC4115 division inhibition protein DicB YP_002270645.1 2155878 D 444450 CDS YP_002270646.1 209396512 6968172 2156063..2156254 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 2156254 6968172 ECH74115_2283 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270646.1 2156063 D 444450 CDS YP_002270647.1 209395776 6967424 2156347..2157477 1 NC_011353.1 exonuclease family protein 2157477 6967424 ECH74115_2284 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002270647.1 2156347 D 444450 CDS YP_002270648.1 209400240 6966632 2157483..2157809 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2157809 6966632 ECH74115_2285 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002270648.1 2157483 D 444450 CDS YP_002270649.1 209399447 6971430 2157806..2158696 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2158696 6971430 ECH74115_2286 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002270649.1 2157806 D 444450 CDS YP_002270650.1 209397980 6970575 2158749..2160131 1 NC_011353.1 identified by match to protein family HMM PF00929; exonuclease family protein 2160131 6970575 ECH74115_2287 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002270650.1 2158749 D 444450 CDS YP_002270651.1 209397228 6968991 2160219..2160455 1 NC_011353.1 identified by match to protein family HMM PF06806; phage excisionase 2160455 6968991 ECH74115_2288 Escherichia coli O157:H7 str. EC4115 phage excisionase YP_002270651.1 2160219 D 444450 CDS YP_002270652.1 209400609 6971066 2160975..2161181 1 NC_011353.1 transposase 2161181 6971066 ECH74115_2290 Escherichia coli O157:H7 str. EC4115 transposase YP_002270652.1 2160975 D 444450 CDS YP_002270653.1 209397241 6971821 complement(2161444..2161770) 1 NC_011353.1 identified by match to protein family HMM PF02694; hypothetical protein 2161770 6971821 ECH74115_2291 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270653.1 2161444 R 444450 CDS YP_002270654.1 209398017 6968199 2161905..2162246 1 NC_011353.1 identified by match to protein family HMM PF06932; hypothetical protein 2162246 6968199 ECH74115_2292 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270654.1 2161905 D 444450 CDS YP_002270655.1 209398880 6969030 2162281..2162841 1 NC_011353.1 identified by match to protein family HMM PF00583; diamine N-acetyltransferase 2162841 speG 6969030 speG Escherichia coli O157:H7 str. EC4115 diamine N-acetyltransferase YP_002270655.1 2162281 D 444450 CDS YP_002270656.1 209399497 6969969 complement(2162844..2163590) 1 NC_011353.1 identified by match to protein family HMM PF06788; hypothetical protein 2163590 6969969 ECH74115_2294 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270656.1 2162844 R 444450 CDS YP_002270657.1 209400471 6970631 2163662..2163967 1 NC_011353.1 identified by match to protein family HMM PF06649; hypothetical protein 2163967 6970631 ECH74115_2295 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270657.1 2163662 D 444450 CDS YP_002270658.1 209400979 6971676 2164166..2166592 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase, A subunit YnfE 2166592 ynfE 6971676 ynfE Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase, A subunit YnfE YP_002270658.1 2164166 D 444450 CDS YP_002270659.1 209396602 6972219 2166680..2169076 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 2169076 6972219 ECH74115_2297 Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase subunit A YP_002270659.1 2166680 D 444450 CDS YP_002270660.1 209399816 6967519 2169087..2169704 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951; anaerobic dimethylsulfoxide reductase subunit B 2169704 dmsB_2 6967519 dmsB_2 Escherichia coli O157:H7 str. EC4115 anaerobic dimethylsulfoxide reductase subunit B YP_002270660.1 2169087 D 444450 CDS YP_002270661.1 209400906 6970973 2169706..2170560 1 NC_011353.1 identified by match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 2170560 dmsC2 6970973 dmsC2 Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase subunit C YP_002270661.1 2169706 D 444450 CDS YP_002270662.1 209400474 6972141 2170603..2171217 1 NC_011353.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 2171217 dmsD 6972141 dmsD Escherichia coli O157:H7 str. EC4115 twin-argninine leader-binding protein DmsD YP_002270662.1 2170603 D 444450 CDS YP_002270663.1 209396428 6971679 2171231..2171344 1 NC_011353.1 identified by glimmer; hypothetical protein 2171344 6971679 ECH74115_2301 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270663.1 2171231 D 444450 CDS YP_002270664.1 209397921 6967335 2171411..2172667 1 NC_011353.1 identified by match to protein family HMM PF00654; voltage-gated ClC-type chloride channel ClcB 2172667 6967335 ECH74115_2303 Escherichia coli O157:H7 str. EC4115 voltage-gated ClC-type chloride channel ClcB YP_002270664.1 2171411 D 444450 CDS YP_002270665.1 209395696 6968921 complement(2172620..2173315) 1 NC_011353.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 2173315 bioD2 6968921 bioD2 Escherichia coli O157:H7 str. EC4115 dithiobiotin synthetase YP_002270665.1 2172620 R 444450 CDS YP_002270666.1 209397493 6966550 complement(2173440..2174660) 1 NC_011353.1 identified by match to protein family HMM PF00480; transcriptional regulator Mic 2174660 mic 6966550 mic Escherichia coli O157:H7 str. EC4115 transcriptional regulator Mic YP_002270666.1 2173440 R 444450 CDS YP_002270667.1 209400317 6968465 complement(2174795..2175688) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2175688 6968465 ECH74115_2305 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002270667.1 2174795 R 444450 CDS YP_002270668.1 209399587 6971513 2175795..2177048 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2177048 ynfM 6971513 ynfM Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002270668.1 2175795 D 444450 CDS YP_002270669.1 209396210 6970728 2177445..2177780 1 NC_011353.1 required for growth and survival under moderately acid conditions; acid shock protein 2177780 6970728 ECH74115_2307 Escherichia coli O157:H7 str. EC4115 acid shock protein YP_002270669.1 2177445 D 444450 CDS YP_002270670.1 209395804 6967098 2178056..2178877 1 NC_011353.1 identified by match to protein family HMM PF00089; peptidase, S1A (chymotrypsin) family 2178877 6967098 ECH74115_2308 Escherichia coli O157:H7 str. EC4115 peptidase, S1A (chymotrypsin) family YP_002270670.1 2178056 D 444450 CDS YP_002270671.1 209400465 6966660 complement(2178916..2179245) 1 NC_011353.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 2179245 mdtI 6966660 mdtI Escherichia coli O157:H7 str. EC4115 multidrug efflux system protein MdtI YP_002270671.1 2178916 R 444450 CDS YP_002270672.1 209398892 6971670 complement(2179232..2179597) 1 NC_011353.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 2179597 mdtJ 6971670 mdtJ Escherichia coli O157:H7 str. EC4115 multidrug efflux system protein MdtJ YP_002270672.1 2179232 R 444450 CDS YP_002270673.1 209396236 6969981 2180009..2181043 1 NC_011353.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 2181043 tqsA 6969981 tqsA Escherichia coli O157:H7 str. EC4115 transporter YP_002270673.1 2180009 D 444450 CDS YP_002270674.1 209396936 6967127 complement(2181068..2182456) 1 NC_011353.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 2182456 pntB 6967127 pntB Escherichia coli O157:H7 str. EC4115 pyridine nucleotide transhydrogenase YP_002270674.1 2181068 R 444450 CDS YP_002270675.1 209397404 6967874 complement(2182467..2184053) 1 NC_011353.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 2184053 pntA 6967874 pntA Escherichia coli O157:H7 str. EC4115 NAD(P) transhydrogenase subunit alpha YP_002270675.1 2182467 R 444450 CDS YP_002270676.1 209395899 6968370 2184523..2185467 1 NC_011353.1 identified by match to protein family HMM PF07338; YdgH protein 2185467 ydgH 6968370 ydgH Escherichia coli O157:H7 str. EC4115 YdgH protein YP_002270676.1 2184523 D 444450 CDS YP_002270677.1 209398615 6966765 2185653..2187035 1 NC_011353.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905; arginine/ornithine antiporter 2187035 arcD 6966765 arcD Escherichia coli O157:H7 str. EC4115 arginine/ornithine antiporter YP_002270677.1 2185653 D 444450 CDS YP_002270678.1 209399782 6969678 2187072..2187794 1 NC_011353.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2187794 6969678 ECH74115_2317 Escherichia coli O157:H7 str. EC4115 short chain dehydrogenase YP_002270678.1 2187072 D 444450 CDS YP_002270679.1 209399051 6970939 complement(2187791..2188126) 1 NC_011353.1 identified by match to protein family HMM PF06942; hypothetical protein 2188126 6970939 ECH74115_2316 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270679.1 2187791 R 444450 CDS YP_002270680.1 209400881 6970153 2188255..2188974 1 NC_011353.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 2188974 rstA 6970153 rstA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator RstA YP_002270680.1 2188255 D 444450 CDS YP_002270681.1 209397092 6972113 2188978..2190279 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein RstB 2190279 rstB 6972113 rstB Escherichia coli O157:H7 str. EC4115 sensor protein RstB YP_002270681.1 2188978 D 444450 CDS YP_002270682.1 209399582 6968038 2190343..2191284 1 NC_011353.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 2191284 tus 6968038 tus Escherichia coli O157:H7 str. EC4115 DNA replication terminus site-binding protein YP_002270682.1 2190343 D 444450 CDS YP_002270683.1 209396648 6970722 complement(2191281..2192684) 1 NC_011353.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 2192684 fumC 6970722 fumC Escherichia coli O157:H7 str. EC4115 fumarate hydratase YP_002270683.1 2191281 R 444450 CDS YP_002270684.1 209397842 6967568 complement(2192827..2194473) 1 NC_011353.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase 2194473 fumA 6967568 fumA Escherichia coli O157:H7 str. EC4115 fumarate hydratase YP_002270684.1 2192827 R 444450 CDS YP_002270685.1 209400753 6968834 2194672..2195847 1 NC_011353.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 2195847 manA 6968834 manA Escherichia coli O157:H7 str. EC4115 mannose-6-phosphate isomerase YP_002270685.1 2194672 D 444450 CDS YP_002270686.1 209400318 6971978 2195948..2197456 1 NC_011353.1 identified by match to protein family HMM PF06097; hypothetical protein 2197456 6971978 ECH74115_2324 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270686.1 2195948 D 444450 CDS YP_002270687.1 209396395 6971317 complement(2198804..2200177) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792; glucuronide transporter 2200177 uidB 6971317 uidB Escherichia coli O157:H7 str. EC4115 glucuronide transporter YP_002270687.1 2198804 R 444450 CDS YP_002270688.1 209395759 6967575 complement(2202378..2202965) 1 NC_011353.1 identified by match to protein family HMM PF00440; transcriptional regulator UidR 2202965 uidR 6967575 uidR Escherichia coli O157:H7 str. EC4115 transcriptional regulator UidR YP_002270688.1 2202378 R 444450 CDS YP_002270689.1 209399425 6966614 complement(2203197..2203964) 1 NC_011353.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 2203964 6966614 ECH74115_2331 Escherichia coli O157:H7 str. EC4115 7-alpha-hydroxysteroid dehydrogenase YP_002270689.1 2203197 R 444450 CDS YP_002270690.1 209397923 6970553 complement(2204076..2205104) 1 NC_011353.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 2205104 malI 6970553 malI Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor MalI YP_002270690.1 2204076 R 444450 CDS YP_002270691.1 209400964 6968923 2205279..2206871 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; PTS system maltose and glucose-specific transporter subunits IICB 2206871 malX 6968923 malX Escherichia coli O157:H7 str. EC4115 PTS system maltose and glucose-specific transporter subunits IICB YP_002270691.1 2205279 D 444450 CDS YP_002270692.1 209400043 6972202 2206881..2208053 1 NC_011353.1 identified by match to protein family HMM PF00155; MalY protein 2208053 malY 6972202 malY Escherichia coli O157:H7 str. EC4115 MalY protein YP_002270692.1 2206881 D 444450 CDS YP_002270693.1 209395849 6971220 2208157..2209158 1 NC_011353.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 2209158 add 6971220 add Escherichia coli O157:H7 str. EC4115 adenosine deaminase YP_002270693.1 2208157 D 444450 CDS YP_002270694.1 209400913 6966707 complement(2209194..2210234) 1 NC_011353.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 2210234 6966707 ECH74115_2336 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002270694.1 2209194 R 444450 CDS YP_002270695.1 209397267 6972149 2210875..2211090 1 NC_011353.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 2211090 6972149 ECH74115_2337 Escherichia coli O157:H7 str. EC4115 oriC-binding nucleoid-associated protein YP_002270695.1 2210875 D 444450 CDS YP_002270696.1 209396347 6968226 2211176..2211616 1 NC_011353.1 hypothetical protein 2211616 6968226 ECH74115_2338 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270696.1 2211176 D 444450 CDS YP_002270697.1 209397687 6967249 2211693..2212274 1 NC_011353.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943; Na(+)-translocating NADH-quinone reductase subunit E 2212274 rnfA 6967249 rnfA Escherichia coli O157:H7 str. EC4115 Na(+)-translocating NADH-quinone reductase subunit E YP_002270697.1 2211693 D 444450 CDS YP_002270698.1 209397589 6968670 2212274..2212852 1 NC_011353.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 2212852 rnfB 6968670 rnfB Escherichia coli O157:H7 str. EC4115 electron transport complex protein RnfB YP_002270698.1 2212274 D 444450 CDS YP_002270699.1 209399637 6968567 2212845..2215163 1 NC_011353.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 2215163 6968567 ECH74115_2341 Escherichia coli O157:H7 str. EC4115 electron transport complex protein RnfC YP_002270699.1 2212845 D 444450 CDS YP_002270700.1 209398754 6970782 2215164..2216222 1 NC_011353.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 2216222 rnfD 6970782 rnfD Escherichia coli O157:H7 str. EC4115 electron transport complex protein RnfD YP_002270700.1 2215164 D 444450 CDS YP_002270701.1 209400825 6969830 2216226..2216846 1 NC_011353.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 2216846 rnfG 6969830 rnfG Escherichia coli O157:H7 str. EC4115 electron transport complex protein RnfG YP_002270701.1 2216226 D 444450 CDS YP_002270702.1 209396599 6972053 2216850..2217545 1 NC_011353.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 2217545 rnfE 6972053 rnfE Escherichia coli O157:H7 str. EC4115 electron transport complex protein RsxE YP_002270702.1 2216850 D 444450 CDS YP_002270703.1 209396011 6967516 2217545..2218180 1 NC_011353.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 2218180 nth 6967516 nth Escherichia coli O157:H7 str. EC4115 endonuclease III YP_002270703.1 2217545 D 444450 CDS YP_002270704.1 209397691 6966884 2218791..2220293 1 NC_011353.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 2220293 tppB 6966884 tppB Escherichia coli O157:H7 str. EC4115 tripeptide transporter permease YP_002270704.1 2218791 D 444450 CDS YP_002270705.1 209397168 6968674 2220399..2221004 1 NC_011353.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathionine S-transferase 2221004 gst 6968674 gst Escherichia coli O157:H7 str. EC4115 glutathionine S-transferase YP_002270705.1 2220399 D 444450 CDS YP_002270706.1 209399578 6968121 complement(2221048..2221908) 1 NC_011353.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 2221908 pdxY 6968121 pdxY Escherichia coli O157:H7 str. EC4115 pyridoxamine kinase YP_002270706.1 2221048 R 444450 CDS YP_002270707.1 209398956 6970718 complement(2221970..2223244) 1 NC_011353.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2223244 tyrS 6970718 tyrS Escherichia coli O157:H7 str. EC4115 tyrosyl-tRNA synthetase YP_002270707.1 2221970 R 444450 CDS YP_002270708.1 209398060 6970050 complement(2223373..2224029) 1 NC_011353.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2224029 pdxH 6970050 pdxH Escherichia coli O157:H7 str. EC4115 pyridoxamine 5'-phosphate oxidase YP_002270708.1 2223373 R 444450 CDS YP_002270709.1 209397448 6969075 complement(2224088..2224411) 1 NC_011353.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 2224411 6969075 ECH74115_2351 Escherichia coli O157:H7 str. EC4115 lysozyme inhibitor YP_002270709.1 2224088 R 444450 CDS YP_002270710.1 209397320 6968418 complement(2224515..2225624) 1 NC_011353.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 2225624 anmK 6968418 anmK Escherichia coli O157:H7 str. EC4115 anhydro-N-acetylmuramic acid kinase YP_002270710.1 2224515 R 444450 CDS YP_002270711.1 209396402 6968282 2225897..2226364 1 NC_011353.1 identified by match to protein family HMM PF05433; outer membrane lipoprotein SlyB 2226364 slyB 6968282 slyB Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein SlyB YP_002270711.1 2225897 D 444450 CDS YP_002270712.1 209395810 6967309 complement(2226411..2226845) 1 NC_011353.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 2226845 6967309 ECH74115_2354 Escherichia coli O157:H7 str. EC4115 transcriptional regulator SlyA YP_002270712.1 2226411 R 444450 CDS YP_002270713.1 209400892 6966666 2227046..2227282 1 NC_011353.1 identified by match to protein family HMM PF07869; hypothetical protein 2227282 6966666 ECH74115_2355 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270713.1 2227046 D 444450 CDS YP_002270714.1 209400309 6972126 2227285..2228142 1 NC_011353.1 identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family 2228142 6972126 ECH74115_2356 Escherichia coli O157:H7 str. EC4115 auxiliary transport protein, membrane fusion protein (MFP) family YP_002270714.1 2227285 D 444450 CDS YP_002270715.1 209399364 6971504 2228163..2230154 1 NC_011353.1 identified by match to protein family HMM PF04632; fusaric acid resistance domain-containing protein 2230154 6971504 ECH74115_2357 Escherichia coli O157:H7 str. EC4115 fusaric acid resistance domain-containing protein YP_002270715.1 2228163 D 444450 CDS YP_002270716.1 209396249 6970487 complement(2230155..2230676) 1 NC_011353.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 2230676 sodC 6970487 sodC Escherichia coli O157:H7 str. EC4115 superoxide dismutase YP_002270716.1 2230155 R 444450 CDS YP_002270717.1 209398926 6970681 2231713..2231832 1 NC_011353.1 identified by glimmer; hypothetical protein 2231832 6970681 ECH74115_2360 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270717.1 2231713 D 444450 CDS YP_002270718.1 209395839 6970019 2232044..2232643 1 NC_011353.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2232643 6970019 ECH74115_2361 Escherichia coli O157:H7 str. EC4115 TetR family transcriptional regulator YP_002270718.1 2232044 D 444450 CDS YP_002270719.1 209398217 6966696 2232680..2233777 1 NC_011353.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 2233777 nemA 6966696 nemA Escherichia coli O157:H7 str. EC4115 N-ethylmaleimide reductase YP_002270719.1 2232680 D 444450 CDS YP_002270720.1 209399842 6969246 2233858..2234265 1 NC_011353.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 2234265 gloA 6969246 gloA Escherichia coli O157:H7 str. EC4115 glyoxalase I YP_002270720.1 2233858 D 444450 CDS YP_002270721.1 209396384 6970999 2234368..2235015 1 NC_011353.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2235015 rnt 6970999 rnt Escherichia coli O157:H7 str. EC4115 ribonuclease T YP_002270721.1 2234368 D 444450 CDS YP_002270722.1 209398820 6967289 2235108..2239724 1 NC_011353.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; ATP-dependent helicase Lhr 2239724 lhr 6967289 lhr Escherichia coli O157:H7 str. EC4115 ATP-dependent helicase Lhr YP_002270722.1 2235108 D 444450 CDS YP_002270723.1 209398586 6969902 complement(2239775..2240122) 1 NC_011353.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; hypothetical protein 2240122 6969902 ECH74115_2366 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270723.1 2239775 R 444450 CDS YP_002270724.1 209397631 6969647 2240457..2241272 1 NC_011353.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 2241272 6969647 ECH74115_2367 Escherichia coli O157:H7 str. EC4115 NlpC/P60 family protein YP_002270724.1 2240457 D 444450 CDS YP_002270725.1 209399418 6968613 2241400..2241981 1 NC_011353.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 2241981 sodB 6968613 sodB Escherichia coli O157:H7 str. EC4115 superoxide dismutase YP_002270725.1 2241400 D 444450 CDS YP_002270726.1 209397024 6970544 complement(2242127..2243296) 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2243296 6970544 ECH74115_2369 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002270726.1 2242127 R 444450 CDS YP_002270727.1 209398936 6967968 complement(2243462..2243581) 1 NC_011353.1 identified by glimmer; membrane protein 2243581 6967968 ECH74115_2370 Escherichia coli O157:H7 str. EC4115 membrane protein YP_002270727.1 2243462 R 444450 CDS YP_002270728.1 209400108 6970030 2243850..2244875 1 NC_011353.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 2244875 purR 6970030 purR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor PurR YP_002270728.1 2243850 D 444450 CDS YP_002270729.1 209399549 6971291 complement(2244872..2245804) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 2245804 6971291 ECH74115_2371 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002270729.1 2244872 R 444450 CDS YP_002270730.1 209400712 6970686 2245917..2247128 1 NC_011353.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2247128 6970686 ECH74115_2373 Escherichia coli O157:H7 str. EC4115 inner membrane transport protein YdhC YP_002270730.1 2245917 D 444450 CDS YP_002270731.1 209395995 6971935 2247419..2248567 1 NC_011353.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 2248567 cfa 6971935 cfa Escherichia coli O157:H7 str. EC4115 cyclopropane-fatty-acyl-phospholipid synthase YP_002270731.1 2247419 D 444450 CDS YP_002270732.1 209396623 6966866 complement(2248607..2249248) 1 NC_011353.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2249248 ribE 6966866 ribE Escherichia coli O157:H7 str. EC4115 riboflavin synthase subunit alpha YP_002270732.1 2248607 R 444450 CDS YP_002270733.1 209397056 6967543 2249463..2250836 1 NC_011353.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 2250836 6967543 ECH74115_2376 Escherichia coli O157:H7 str. EC4115 multidrug efflux protein YP_002270733.1 2249463 D 444450 CDS YP_002270734.1 209398905 6968002 complement(2250877..2252133) 1 NC_011353.1 hypothetical protein 2252133 6968002 ECH74115_2377 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270734.1 2250877 R 444450 CDS YP_002270735.1 209399641 6972367 2252706..2253011 1 NC_011353.1 identified by match to protein family HMM PF08803; hypothetical protein 2253011 ydhR 6972367 ydhR Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270735.1 2252706 D 444450 CDS YP_002270736.1 209400503 6970786 2253137..2254741 1 NC_011353.1 hypothetical protein 2254741 6970786 ECH74115_2381 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270736.1 2253137 D 444450 CDS YP_002270737.1 209399528 6971708 complement(2254753..2255565) 1 NC_011353.1 hypothetical protein 2255565 6971708 ECH74115_2382 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270737.1 2254753 R 444450 CDS YP_002270738.1 209399013 6970664 complement(2255569..2256354) 1 NC_011353.1 identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit 2256354 6970664 ECH74115_2383 Escherichia coli O157:H7 str. EC4115 nickel-dependent hydrogenase, b-type cytochrome subunit YP_002270738.1 2255569 R 444450 CDS YP_002270739.1 209396610 6970113 complement(2256351..2257070) 1 NC_011353.1 identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein 2257070 6970113 ECH74115_2384 Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster-binding protein YP_002270739.1 2256351 R 444450 CDS YP_002270740.1 209395698 6967529 complement(2257083..2257721) 1 NC_011353.1 hypothetical protein 2257721 6967529 ECH74115_2385 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270740.1 2257083 R 444450 CDS YP_002270741.1 209400724 6966552 complement(2257734..2259836) 1 NC_011353.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730; oxidoreductase 2259836 6966552 ECH74115_2386 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002270741.1 2257734 R 444450 CDS YP_002270742.1 209400156 6971948 complement(2259857..2260483) 1 NC_011353.1 identified by match to protein family HMM PF00037; hypothetical protein 2260483 6971948 ECH74115_2387 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270742.1 2259857 R 444450 CDS YP_002270743.1 209398949 6971342 2260511..2260648 1 NC_011353.1 identified by glimmer; hypothetical protein 2260648 6971342 ECH74115_2388 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270743.1 2260511 D 444450 CDS YP_002270744.1 209400728 6970043 complement(2260939..2261109) 1 NC_011353.1 hypothetical protein 2261109 6970043 ECH74115_2389 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270744.1 2260939 R 444450 CDS YP_002270745.1 209397761 6971952 2261705..2263117 1 NC_011353.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2263117 pykF 6971952 pykF Escherichia coli O157:H7 str. EC4115 pyruvate kinase YP_002270745.1 2261705 D 444450 CDS YP_002270746.1 209395893 6968748 2263428..2263664 1 NC_011353.1 identified by match to protein family HMM PF04728; major outer membrane lipoprotein 2263664 lpp 6968748 lpp Escherichia coli O157:H7 str. EC4115 major outer membrane lipoprotein YP_002270746.1 2263428 D 444450 CDS YP_002270747.1 209399001 6966759 complement(2263727..2264731) 1 NC_011353.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM domain/ErfK/YbiS/YcfS/YnhG family protein 2264731 6966759 ECH74115_2392 Escherichia coli O157:H7 str. EC4115 LysM domain/ErfK/YbiS/YcfS/YnhG family protein YP_002270747.1 2263727 R 444450 CDS YP_002270748.1 209400688 6970100 complement(2264880..2265296) 1 NC_011353.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 2265296 sufE 6970100 sufE Escherichia coli O157:H7 str. EC4115 cysteine desufuration protein SufE YP_002270748.1 2264880 R 444450 CDS YP_002270749.1 209398201 6971908 complement(2265309..2266529) 1 NC_011353.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 2266529 sufS 6971908 sufS Escherichia coli O157:H7 str. EC4115 bifunctional cysteine desulfurase/selenocysteine lyase YP_002270749.1 2265309 R 444450 CDS YP_002270750.1 209397107 6969229 complement(2266526..2267797) 1 NC_011353.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 2267797 sufD 6969229 sufD Escherichia coli O157:H7 str. EC4115 cysteine desulfurase activator complex subunit SufD YP_002270750.1 2266526 R 444450 CDS YP_002270751.1 209396355 6968056 complement(2267772..2268518) 1 NC_011353.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 2268518 sufC 6968056 sufC Escherichia coli O157:H7 str. EC4115 cysteine desulfurase YP_002270751.1 2267772 R 444450 CDS YP_002270752.1 209395906 6967257 complement(2268528..2270015) 1 NC_011353.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 2270015 sufB 6967257 sufB Escherichia coli O157:H7 str. EC4115 cysteine desulfurase activator complex subunit SufB YP_002270752.1 2268528 R 444450 CDS YP_002270753.1 209399898 6966772 complement(2270024..2270392) 1 NC_011353.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 2270392 sufA 6966772 sufA Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster assembly scaffold protein YP_002270753.1 2270024 R 444450 CDS YP_002270754.1 209400116 6972289 complement(2270941..2271129) 1 NC_011353.1 hypothetical protein 2271129 6972289 ECH74115_2400 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270754.1 2270941 R 444450 CDS YP_002270755.1 209399366 6971299 complement(2271229..2271639) 1 NC_011353.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 2271639 ydiL 6971299 ydiL Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270755.1 2271229 R 444450 CDS YP_002270756.1 209396798 6970490 complement(2271636..2274692) 1 NC_011353.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding 2274692 6970490 ECH74115_2402 Escherichia coli O157:H7 str. EC4115 oxidoreductase, FAD-binding YP_002270756.1 2271636 R 444450 CDS YP_002270757.1 209397418 6967730 2275081..2276193 1 NC_011353.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 2276193 ydiK 6967730 ydiK Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002270757.1 2275081 D 444450 CDS YP_002270758.1 209398190 6972307 2276622..2276978 1 NC_011353.1 identified by match to protein family HMM PF08965; hypothetical protein 2276978 6972307 ECH74115_2405 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270758.1 2276622 D 444450 CDS YP_002270759.1 209400261 6969218 2277138..2278292 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2278292 ydiM 6969218 ydiM Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002270759.1 2277138 D 444450 CDS YP_002270760.1 209400911 6971454 2278519..2279784 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2279784 6971454 ECH74115_2407 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002270760.1 2278519 D 444450 CDS YP_002270761.1 209396504 6972147 2279796..2280662 1 NC_011353.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2280662 6972147 ECH74115_2408 Escherichia coli O157:H7 str. EC4115 quinate/shikimate dehydrogenase YP_002270761.1 2279796 D 444450 CDS YP_002270762.1 209399707 6967416 2280693..2281451 1 NC_011353.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2281451 aroD 6967416 aroD Escherichia coli O157:H7 str. EC4115 3-dehydroquinate dehydratase YP_002270762.1 2280693 D 444450 CDS YP_002270763.1 209397911 6970858 2281596..2283191 1 NC_011353.1 identified by match to protein family HMM PF01144; propionate CoA-transferase 2283191 pct 6970858 pct Escherichia coli O157:H7 str. EC4115 propionate CoA-transferase YP_002270763.1 2281596 D 444450 CDS YP_002270764.1 209396182 6968910 2283205..2284356 1 NC_011353.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 2284356 6968910 ECH74115_2411 Escherichia coli O157:H7 str. EC4115 acyl-CoA dehydrogenase YP_002270764.1 2283205 D 444450 CDS YP_002270765.1 209399351 6967068 complement(2284399..2285310) 1 NC_011353.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883; AraC family transcriptional regulator 2285310 6967068 ECH74115_2412 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002270765.1 2284399 R 444450 CDS YP_002270766.1 209400961 6970472 complement(2285413..2285589) 1 NC_011353.1 identified by glimmer; hypothetical protein 2285589 6970472 ECH74115_2413 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270766.1 2285413 R 444450 CDS YP_002270767.1 209398682 6972199 2285626..2286390 1 NC_011353.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 2286390 6972199 ECH74115_2414 Escherichia coli O157:H7 str. EC4115 electron transfer flavoprotein YdiQ YP_002270767.1 2285626 D 444450 CDS YP_002270768.1 209399457 6969752 2286410..2287348 1 NC_011353.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2287348 6969752 ECH74115_2415 Escherichia coli O157:H7 str. EC4115 electron transfer flavoprotein subunit YdiR YP_002270768.1 2286410 D 444450 CDS YP_002270769.1 209396032 6970586 2287404..2288693 1 NC_011353.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; hypothetical protein 2288693 6970586 ECH74115_2416 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270769.1 2287404 D 444450 CDS YP_002270770.1 209396754 6966908 2288690..2288983 1 NC_011353.1 iron-sulfur cluster-binding protein 2288983 6966908 ECH74115_2417 Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster-binding protein YP_002270770.1 2288690 D 444450 CDS YP_002270771.1 209395961 6971859 complement(2290742..2293120) 1 NC_011353.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 2293120 ppsA 6971859 ppsA Escherichia coli O157:H7 str. EC4115 phosphoenolpyruvate synthase YP_002270771.1 2290742 R 444450 CDS YP_002270772.1 209399132 6966828 complement(2293174..2293341) 1 NC_011353.1 identified by glimmer; hypothetical protein 2293341 6966828 ECH74115_2420 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270772.1 2293174 R 444450 CDS YP_002270773.1 209400227 6970235 2293453..2294286 1 NC_011353.1 identified by match to protein family HMM PF03618; hypothetical protein 2294286 6970235 ECH74115_2421 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270773.1 2293453 D 444450 CDS YP_002270774.1 209398312 6971417 2294443..2295489 1 NC_011353.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2295489 aroH 6971417 aroH Escherichia coli O157:H7 str. EC4115 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002270774.1 2294443 D 444450 CDS YP_002270775.1 209400588 6969349 2295594..2295812 1 NC_011353.1 hypothetical protein 2295812 6969349 ECH74115_2423 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270775.1 2295594 D 444450 CDS YP_002270776.1 209398355 6971799 complement(2295816..2297252) 1 NC_011353.1 identified by match to protein family HMM PF02696; hypothetical protein 2297252 6971799 ECH74115_2424 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270776.1 2295816 R 444450 CDS YP_002270777.1 209397587 6969396 complement(2297315..2298028) 1 NC_011353.1 hypothetical protein 2298028 6969396 ECH74115_2425 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270777.1 2297315 R 444450 CDS YP_002270778.1 209396057 6968565 complement(2298275..2298739) 1 NC_011353.1 identified by match to protein family HMM PF00877; lipoprotein, NlpC/P60 family 2298739 6968565 ECH74115_2426 Escherichia coli O157:H7 str. EC4115 lipoprotein, NlpC/P60 family YP_002270778.1 2298275 R 444450 CDS YP_002270779.1 209396820 6966934 complement(2298817..2299566) 1 NC_011353.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 2299566 btuD 6966934 btuD Escherichia coli O157:H7 str. EC4115 vitamin B12-transporter ATPase YP_002270779.1 2298817 R 444450 CDS YP_002270780.1 209399909 6967752 complement(2299566..2300117) 1 NC_011353.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 2300117 btuE 6967752 btuE Escherichia coli O157:H7 str. EC4115 glutathione peroxidase YP_002270780.1 2299566 R 444450 CDS YP_002270781.1 209400661 6971073 complement(2300180..2301160) 1 NC_011353.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 2301160 btuC 6971073 btuC Escherichia coli O157:H7 str. EC4115 vtamin B12-transporter permease YP_002270781.1 2300180 R 444450 CDS YP_002270782.1 209399095 6971877 complement(2301261..2301560) 1 NC_011353.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 2301560 ihfA 6971877 ihfA Escherichia coli O157:H7 str. EC4115 integration host factor subunit alpha YP_002270782.1 2301261 R 444450 CDS YP_002270783.1 209399911 6970197 complement(2301565..2303952) 1 NC_011353.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2303952 pheT 6970197 pheT Escherichia coli O157:H7 str. EC4115 phenylalanyl-tRNA synthetase subunit beta YP_002270783.1 2301565 R 444450 CDS YP_002270784.1 209397640 6971075 complement(2303967..2304950) 1 NC_011353.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2304950 pheS 6971075 pheS Escherichia coli O157:H7 str. EC4115 phenylalanyl-tRNA synthetase subunit alpha YP_002270784.1 2303967 R 444450 CDS YP_002270785.1 209399409 6968623 complement(2305139..2305273) 1 NC_011353.1 hypothetical protein 2305273 6968623 ECH74115_2433 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270785.1 2305139 R 444450 CDS YP_002270786.1 209396995 6970535 complement(2305400..2305756) 1 NC_011353.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2305756 rplT 6970535 rplT Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L20 YP_002270786.1 2305400 R 444450 CDS YP_002270787.1 209397787 6967937 complement(2305809..2306006) 1 NC_011353.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 2306006 rpmI 6967937 rpmI Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L35 YP_002270787.1 2305809 R 444450 CDS YP_002270788.1 209399706 6968775 complement(2306103..2306537) 1 NC_011353.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2306537 infC 6968775 infC Escherichia coli O157:H7 str. EC4115 translation initiation factor IF-3 YP_002270788.1 2306103 R 444450 CDS YP_002270789.1 209400429 6970857 complement(2306649..2308577) 1 NC_011353.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 2308577 thrS 6970857 thrS Escherichia coli O157:H7 str. EC4115 threonyl-tRNA synthetase YP_002270789.1 2306649 R 444450 CDS YP_002270790.1 209398577 6971631 2309100..2310998 1 NC_011353.1 identified by match to protein family HMM PF07906; hypothetical protein 2310998 6971631 ECH74115_2438 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270790.1 2309100 D 444450 CDS YP_002270791.1 209399189 6969638 2311158..2311280 1 NC_011353.1 hypothetical protein 2311280 6969638 ECH74115_2439 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270791.1 2311158 D 444450 CDS YP_002270792.1 209398257 6970297 complement(2311333..2312091) 1 NC_011353.1 identified by match to protein family HMM PF04338; hypothetical protein 2312091 6970297 ECH74115_2440 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270792.1 2311333 R 444450 CDS YP_002270793.1 209398695 6969289 2312378..2313307 1 NC_011353.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 6-phosphofructokinase 2313307 pfkB 6969289 pfkB Escherichia coli O157:H7 str. EC4115 6-phosphofructokinase YP_002270793.1 2312378 D 444450 CDS YP_002270794.1 209396496 6969767 2313408..2313698 1 NC_011353.1 hypothetical protein 2313698 6969767 ECH74115_2442 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270794.1 2313408 D 444450 CDS YP_002270795.1 209397430 6967408 2313804..2314664 1 NC_011353.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881; fructosamine kinase 2314664 6967408 ECH74115_2443 Escherichia coli O157:H7 str. EC4115 fructosamine kinase YP_002270795.1 2313804 D 444450 CDS YP_002270796.1 209396685 6968399 complement(2314705..2315241) 1 NC_011353.1 hypothetical protein 2315241 6968399 ECH74115_2444 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270796.1 2314705 R 444450 CDS YP_002270797.1 209396268 6967606 2315388..2316056 1 NC_011353.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2316056 6967606 ECH74115_2445 Escherichia coli O157:H7 str. EC4115 2-deoxyglucose-6-phosphatase YP_002270797.1 2315388 D 444450 CDS YP_002270798.1 209400224 6967161 2316219..2316809 1 NC_011353.1 identified by match to protein family HMM PF04307; hypothetical protein 2316809 6967161 ECH74115_2446 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270798.1 2316219 D 444450 CDS YP_002270799.1 209399128 6971413 2316942..2318333 1 NC_011353.1 identified by match to protein family HMM PF00375; transporter dicarboxylate/amino acid:cation (Na+ or H+) symporter (DAACS) family 2318333 6971413 ECH74115_2447 Escherichia coli O157:H7 str. EC4115 transporter dicarboxylate/amino acid:cation (Na+ or H+) symporter (DAACS) family YP_002270799.1 2316942 D 444450 CDS YP_002270800.1 209397961 6969442 complement(2319428..2319670) 1 NC_011353.1 cell division modulator 2319670 cedA 6969442 cedA Escherichia coli O157:H7 str. EC4115 cell division modulator YP_002270800.1 2319428 R 444450 CDS YP_002270801.1 209396422 6968966 2319874..2322135 1 NC_011353.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2322135 katE 6968966 katE Escherichia coli O157:H7 str. EC4115 hydroperoxidase II YP_002270801.1 2319874 D 444450 CDS YP_002270802.1 209396840 6967329 complement(2322182..2322940) 1 NC_011353.1 identified by match to protein family HMM PF04794; hypothetical protein 2322940 6967329 ECH74115_2451 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270802.1 2322182 R 444450 CDS YP_002270803.1 209396083 6967773 complement(2322953..2324305) 1 NC_011353.1 identified by match to protein family HMM PF02056; 6-phospho-beta-glucosidase 2324305 chbF 6967773 chbF Escherichia coli O157:H7 str. EC4115 6-phospho-beta-glucosidase YP_002270803.1 2322953 R 444450 CDS YP_002270804.1 209396114 6966962 complement(2324410..2325249) 1 NC_011353.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 2325249 chbR 6966962 chbR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator ChbR YP_002270804.1 2324410 R 444450 CDS YP_002270805.1 209398511 6966994 complement(2325260..2325607) 1 NC_011353.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2325607 chbA 6966994 chbA Escherichia coli O157:H7 str. EC4115 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_002270805.1 2325260 R 444450 CDS YP_002270806.1 209400404 6969569 complement(2325661..2327019) 1 NC_011353.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2327019 chbC 6969569 chbC Escherichia coli O157:H7 str. EC4115 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_002270806.1 2325661 R 444450 CDS YP_002270807.1 209398244 6971605 complement(2327104..2327424) 1 NC_011353.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2327424 chbB 6971605 chbB Escherichia coli O157:H7 str. EC4115 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_002270807.1 2327104 R 444450 CDS YP_002270808.1 209397542 6969276 complement(2327724..2328062) 1 NC_011353.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 2328062 osmE 6969276 osmE Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator OsmE YP_002270808.1 2327724 R 444450 CDS YP_002270809.1 209396744 6968516 2328264..2329091 1 NC_011353.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2329091 nadE 6968516 nadE Escherichia coli O157:H7 str. EC4115 NAD synthetase YP_002270809.1 2328264 D 444450 CDS YP_002270810.1 209400159 6967670 2329321..2330208 1 NC_011353.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2330208 cho 6967670 cho Escherichia coli O157:H7 str. EC4115 nucleotide excision repair endonuclease YP_002270810.1 2329321 D 444450 CDS YP_002270811.1 209396147 6971345 complement(2330168..2330743) 1 NC_011353.1 identified by match to protein family HMM PF05962; hypothetical protein 2330743 6971345 ECH74115_2459 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270811.1 2330168 R 444450 CDS YP_002270812.1 209399896 6967030 complement(2330946..2331431) 1 NC_011353.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 2331431 spy 6967030 spy Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270812.1 2330946 R 444450 CDS YP_002270813.1 209399337 6971058 complement(2331761..2332729) 1 NC_011353.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 2332729 astE 6971058 astE Escherichia coli O157:H7 str. EC4115 succinylglutamate desuccinylase YP_002270813.1 2331761 R 444450 CDS YP_002270814.1 209397568 6970457 complement(2332722..2334065) 1 NC_011353.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 2334065 astB 6970457 astB Escherichia coli O157:H7 str. EC4115 succinylarginine dihydrolase YP_002270814.1 2332722 R 444450 CDS YP_002270815.1 209399129 6968544 complement(2334062..2335540) 1 NC_011353.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2335540 astD 6968544 astD Escherichia coli O157:H7 str. EC4115 succinylglutamic semialdehyde dehydrogenase YP_002270815.1 2334062 R 444450 CDS YP_002270816.1 209398676 6970231 complement(2335537..2336571) 1 NC_011353.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03243; match to protein family HMM TIGR03244; arginine succinyltransferase 2336571 astA 6970231 astA Escherichia coli O157:H7 str. EC4115 arginine succinyltransferase YP_002270816.1 2335537 R 444450 CDS YP_002270817.1 209400956 6969746 complement(2336568..2337788) 1 NC_011353.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 2337788 astC 6969746 astC Escherichia coli O157:H7 str. EC4115 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_002270817.1 2336568 R 444450 CDS YP_002270818.1 209396663 6972194 2338051..2338221 1 NC_011353.1 identified by glimmer; hypothetical protein 2338221 6972194 ECH74115_2467 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270818.1 2338051 D 444450 CDS YP_002270819.1 209395934 6967584 2338234..2339040 1 NC_011353.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2339040 xth 6967584 xth Escherichia coli O157:H7 str. EC4115 exonuclease III YP_002270819.1 2338234 D 444450 CDS YP_002270820.1 209397727 6966801 2339207..2339917 1 NC_011353.1 identified by match to protein family HMM PF09335; hypothetical protein 2339917 6966801 ECH74115_2469 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270820.1 2339207 D 444450 CDS YP_002270821.1 209397135 6968712 2339922..2340599 1 NC_011353.1 hypothetical protein 2340599 6968712 ECH74115_2470 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270821.1 2339922 D 444450 CDS YP_002270822.1 209399590 6968085 2340614..2341321 1 NC_011353.1 identified by match to protein family HMM PF09335; hypothetical protein 2341321 6968085 ECH74115_2471 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270822.1 2340614 D 444450 CDS YP_002270823.1 209398487 6970731 2341321..2341869 1 NC_011353.1 identified by match to protein family HMM PF02627; carboxymuconolactone decarboxylase family protein 2341869 6970731 ECH74115_2472 Escherichia coli O157:H7 str. EC4115 carboxymuconolactone decarboxylase family protein YP_002270823.1 2341321 D 444450 CDS YP_002270824.1 209399720 6969544 2341879..2343045 1 NC_011353.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 2343045 6969544 ECH74115_2473 Escherichia coli O157:H7 str. EC4115 ABC transporter substrate-binding protein YP_002270824.1 2341879 D 444450 CDS YP_002270825.1 209399526 6970873 2343018..2344553 1 NC_011353.1 ABC transporter permease 2344553 ynjC 6970873 ynjC Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002270825.1 2343018 D 444450 CDS YP_002270826.1 209397978 6970662 2344553..2345206 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2345206 6970662 ECH74115_2475 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002270826.1 2344553 D 444450 CDS YP_002270827.1 209397120 6968988 2345273..2346580 1 NC_011353.1 identified by match to protein family HMM PF00581; rhodanese-like domain-containing protein 2346580 6968988 ECH74115_2476 Escherichia coli O157:H7 str. EC4115 rhodanese-like domain-containing protein YP_002270827.1 2345273 D 444450 CDS YP_002270828.1 209397500 6968069 complement(2346589..2347209) 1 NC_011353.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 2347209 6968069 ECH74115_2477 Escherichia coli O157:H7 str. EC4115 CDP-alcohol phosphatidyltransferase YP_002270828.1 2346589 R 444450 CDS YP_002270829.1 209400758 6968472 2347296..2347703 1 NC_011353.1 identified by match to protein family HMM PF00293; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2347703 nudG 6968472 nudG Escherichia coli O157:H7 str. EC4115 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_002270829.1 2347296 D 444450 CDS YP_002270830.1 209395916 6971983 complement(2347669..2347941) 1 NC_011353.1 identified by match to protein family HMM PF07383; hypothetical protein 2347941 6971983 ECH74115_2478 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270830.1 2347669 R 444450 CDS YP_002270831.1 209400147 6966783 complement(2348026..2348139) 1 NC_011353.1 identified by glimmer; hypothetical protein 2348139 6966783 ECH74115_2480 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270831.1 2348026 R 444450 CDS YP_002270832.1 209399515 6971333 2348177..2349520 1 NC_011353.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2349520 gdhA 6971333 gdhA Escherichia coli O157:H7 str. EC4115 glutamate dehydrogenase YP_002270832.1 2348177 D 444450 CDS YP_002270833.1 209398995 6970650 complement(2349637..2350677) 1 NC_011353.1 hypothetical protein 2350677 6970650 ECH74115_2482 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270833.1 2349637 R 444450 CDS YP_002270834.1 209398550 6970094 complement(2350805..2352766) 1 NC_011353.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2352766 topB 6970094 topB Escherichia coli O157:H7 str. EC4115 DNA topoisomerase III YP_002270834.1 2350805 R 444450 CDS YP_002270835.1 209396660 6969610 complement(2352771..2353814) 1 NC_011353.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2353814 selD 6969610 selD Escherichia coli O157:H7 str. EC4115 selenophosphate synthetase YP_002270835.1 2352771 R 444450 CDS YP_002270836.1 209395863 6967581 complement(2353931..2354482) 1 NC_011353.1 identified by match to protein family HMM PF00881; hypothetical protein 2354482 6967581 ECH74115_2485 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270836.1 2353931 R 444450 CDS YP_002270837.1 209400845 6966725 2354643..2356499 1 NC_011353.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2356499 sppA 6966725 sppA Escherichia coli O157:H7 str. EC4115 protease 4 YP_002270837.1 2354643 D 444450 CDS YP_002270838.1 209400024 6972076 2356615..2357325 1 NC_011353.1 identified by match to protein family HMM PF04402; hypothetical protein 2357325 6972076 ECH74115_2487 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270838.1 2356615 D 444450 CDS YP_002270839.1 209399640 6971199 2357457..2358473 1 NC_011353.1 converts asparagine to aspartate and ammonia; asparaginase 2358473 ansA 6971199 ansA Escherichia coli O157:H7 str. EC4115 asparaginase YP_002270839.1 2357457 D 444450 CDS YP_002270840.1 209398832 6970785 2358484..2359125 1 NC_011353.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2359125 pncA 6970785 pncA Escherichia coli O157:H7 str. EC4115 nicotinamidase/pyrazinamidase YP_002270840.1 2358484 D 444450 CDS YP_002270841.1 209397145 6969915 complement(2359218..2360468) 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; inner membrane metabolite transport protein YdjE 2360468 6969915 ECH74115_2490 Escherichia coli O157:H7 str. EC4115 inner membrane metabolite transport protein YdjE YP_002270841.1 2359218 R 444450 CDS YP_002270842.1 209399150 6968097 2360531..2360857 1 NC_011353.1 overlaps another CDS with the same product name; IS629, transposase orfA 2360857 6968097 ECH74115_2491 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002270842.1 2360531 D 444450 CDS YP_002270843.1 209399831 6970257 2360857..2361744 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2361744 6970257 ECH74115_2492 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002270843.1 2360857 D 444450 CDS YP_002270844.1 209398382 6970988 2361862..2362005 1 NC_011353.1 identified by glimmer; hypothetical protein 2362005 6970988 ECH74115_2493 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270844.1 2361862 D 444450 CDS YP_002270845.1 209400591 6969425 complement(2362007..2362765) 1 NC_011353.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; DeoR family transcriptional regulator 2362765 6969425 ECH74115_2494 Escherichia coli O157:H7 str. EC4115 DeoR family transcriptional regulator YP_002270845.1 2362007 R 444450 CDS YP_002270846.1 209399877 6971802 complement(2362902..2363882) 1 NC_011353.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 2363882 6971802 ECH74115_2495 Escherichia coli O157:H7 str. EC4115 oxidoreductase, aldo/keto reductase family YP_002270846.1 2362902 R 444450 CDS YP_002270847.1 209396793 6971036 complement(2363892..2364824) 1 NC_011353.1 identified by match to protein family HMM PF00294; kinase, pfkB family 2364824 6971036 ECH74115_2496 Escherichia coli O157:H7 str. EC4115 kinase, pfkB family YP_002270847.1 2363892 R 444450 CDS YP_002270848.1 209396071 6967724 complement(2364829..2365665) 1 NC_011353.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; fructose-bisphosphate aldolase, class II family 2365665 6967724 ECH74115_2497 Escherichia coli O157:H7 str. EC4115 fructose-bisphosphate aldolase, class II family YP_002270848.1 2364829 R 444450 CDS YP_002270849.1 209398191 6966950 complement(2365686..2366729) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; sorbitol dehydrogenase 2366729 gutB 6966950 gutB Escherichia coli O157:H7 str. EC4115 sorbitol dehydrogenase YP_002270849.1 2365686 R 444450 CDS YP_002270850.1 209397498 6969219 complement(2366746..2368125) 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 2368125 ydjK 6969219 ydjK Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002270850.1 2366746 R 444450 CDS YP_002270851.1 209399082 6968470 complement(2368152..2369228) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 2369228 6968470 ECH74115_2500 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002270851.1 2368152 R 444450 CDS YP_002270852.1 209398480 6970184 complement(2369598..2369870) 1 NC_011353.1 identified by match to protein family HMM PF07023; hypothetical protein 2369870 6970184 ECH74115_2501 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270852.1 2369598 R 444450 CDS YP_002270853.1 209396138 6969537 complement(2369912..2370325) 1 NC_011353.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2370325 msrB 6969537 msrB Escherichia coli O157:H7 str. EC4115 methionine sulfoxide reductase B YP_002270853.1 2369912 R 444450 CDS YP_002270854.1 209398232 6967021 2370667..2371662 1 NC_011353.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; gIyceraldehyde-3-phosphate dehydrogenase 2371662 gapA 6967021 gapA Escherichia coli O157:H7 str. EC4115 gIyceraldehyde-3-phosphate dehydrogenase YP_002270854.1 2370667 D 444450 CDS YP_002270855.1 209396908 6969263 2371746..2372630 1 NC_011353.1 identified by match to protein family HMM PF01263; aldose 1-epimerase family protein 2372630 6969263 ECH74115_2504 Escherichia coli O157:H7 str. EC4115 aldose 1-epimerase family protein YP_002270855.1 2371746 D 444450 CDS YP_002270856.1 209400049 6967846 complement(2372681..2373535) 1 NC_011353.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 2373535 6967846 ECH74115_2505 Escherichia coli O157:H7 str. EC4115 oxidoreductase, aldo/keto reductase family YP_002270856.1 2372681 R 444450 CDS YP_002270857.1 209400624 6971226 complement(2373625..2374371) 1 NC_011353.1 identified by match to protein family HMM PF06629; MltA-interacting protein MipA 2374371 mipA 6971226 mipA Escherichia coli O157:H7 str. EC4115 MltA-interacting protein MipA YP_002270857.1 2373625 R 444450 CDS YP_002270858.1 209398535 6971836 2374807..2376741 1 NC_011353.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298; serine kinase family protein 2376741 6971836 ECH74115_2507 Escherichia coli O157:H7 str. EC4115 serine kinase family protein YP_002270858.1 2374807 D 444450 CDS YP_002270859.1 209397249 6969594 2376854..2378137 1 NC_011353.1 identified by match to protein family HMM PF04285; hypothetical protein 2378137 6969594 ECH74115_2508 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270859.1 2376854 D 444450 CDS YP_002270860.1 209397879 6968207 2378425..2379759 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2379759 6968207 ECH74115_2509 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002270860.1 2378425 D 444450 CDS YP_002270861.1 209395799 6968875 2379940..2381430 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2381430 6968875 ECH74115_2510 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002270861.1 2379940 D 444450 CDS YP_002270862.1 209396307 6966655 2381473..2381976 1 NC_011353.1 identified by match to protein family HMM PF04073; YbaK/prolyl-tRNA synthetase-associated domain-containing protein 2381976 6966655 ECH74115_2511 Escherichia coli O157:H7 str. EC4115 YbaK/prolyl-tRNA synthetase-associated domain-containing protein YP_002270862.1 2381473 D 444450 CDS YP_002270863.1 209400292 6967202 complement(2381977..2382129) 1 NC_011353.1 hypothetical protein 2382129 6967202 ECH74115_2512 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270863.1 2381977 R 444450 CDS YP_002270864.1 209399969 6971486 2382251..2382697 1 NC_011353.1 identified by match to protein family HMM PF04284; hypothetical protein 2382697 6971486 ECH74115_2514 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270864.1 2382251 D 444450 CDS YP_002270865.1 209399087 6971140 complement(2382654..2383463) 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2383463 6971140 ECH74115_2513 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002270865.1 2382654 R 444450 CDS YP_002270866.1 209400545 6970189 2383572..2384753 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00896; inner membrane transport protein yeaN 2384753 yeaN 6970189 yeaN Escherichia coli O157:H7 str. EC4115 inner membrane transport protein yeaN YP_002270866.1 2383572 D 444450 CDS YP_002270867.1 209397599 6971754 2384808..2385155 1 NC_011353.1 identified by match to protein family HMM PF04343; hypothetical protein 2385155 6971754 ECH74115_2516 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270867.1 2384808 D 444450 CDS YP_002270868.1 209398179 6968578 complement(2385177..2385431) 1 NC_011353.1 identified by match to protein family HMM PF03891; lipoprotein 2385431 6968578 ECH74115_2517 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270868.1 2385177 R 444450 CDS YP_002270869.1 209398482 6969205 2385485..2386639 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; GAF domain/diguanylate cyclase (GGDEF) domain-containing protein 2386639 6969205 ECH74115_2518 Escherichia coli O157:H7 str. EC4115 GAF domain/diguanylate cyclase (GGDEF) domain-containing protein YP_002270869.1 2385485 D 444450 CDS YP_002270870.1 209399041 6969539 2386731..2386847 1 NC_011353.1 hypothetical protein 2386847 6969539 ECH74115_2519 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270870.1 2386731 D 444450 CDS YP_002270871.1 209399028 6970143 complement(2386906..2387154) 1 NC_011353.1 identified by match to protein family HMM PF04226; hypothetical protein 2387154 6970143 ECH74115_2520 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270871.1 2386906 R 444450 CDS YP_002270872.1 209399935 6970128 complement(2387301..2387483) 1 NC_011353.1 identified by match to protein family HMM PF08956; hypothetical protein 2387483 6970128 ECH74115_2521 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270872.1 2387301 R 444450 CDS YP_002270873.1 209396150 6971100 complement(2387487..2387846) 1 NC_011353.1 identified by match to protein family HMM PF09313; hypothetical protein 2387846 6971100 ECH74115_2522 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270873.1 2387487 R 444450 CDS YP_002270874.1 209397777 6967033 2387817..2387951 1 NC_011353.1 identified by glimmer; hypothetical protein 2387951 6967033 ECH74115_2523 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270874.1 2387817 D 444450 CDS YP_002270875.1 209400042 6968765 complement(2388019..2388657) 1 NC_011353.1 identified by match to protein family HMM PF01810; leucine export protein LeuE 2388657 6968765 ECH74115_2524 Escherichia coli O157:H7 str. EC4115 leucine export protein LeuE YP_002270875.1 2388019 R 444450 CDS YP_002270876.1 209395982 6971218 complement(2388784..2389707) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2389707 6971218 ECH74115_2525 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002270876.1 2388784 R 444450 CDS YP_002270877.1 209399002 6966852 2389810..2390895 1 NC_011353.1 identified by match to protein family HMM PF00180; match to protein family HMM TIGR02089; tartrate dehydrogenase/decarboxylase 2390895 ttuC 6966852 ttuC Escherichia coli O157:H7 str. EC4115 tartrate dehydrogenase/decarboxylase YP_002270877.1 2389810 D 444450 CDS YP_002270878.1 209399557 6970101 2391146..2392756 1 NC_011353.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2392756 6970101 ECH74115_2527 Escherichia coli O157:H7 str. EC4115 transporter YP_002270878.1 2391146 D 444450 CDS YP_002270879.1 209397683 6970695 2392788..2393912 1 NC_011353.1 identified by match to protein family HMM PF00355; Rieske 2Fe-2S domain-containing protein 2393912 6970695 ECH74115_2528 Escherichia coli O157:H7 str. EC4115 Rieske 2Fe-2S domain-containing protein YP_002270879.1 2392788 D 444450 CDS YP_002270880.1 209398418 6968666 2393968..2394933 1 NC_011353.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein 2394933 6968666 ECH74115_2529 Escherichia coli O157:H7 str. EC4115 oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein YP_002270880.1 2393968 D 444450 CDS YP_002270881.1 209396542 6969465 complement(2394987..2396114) 1 NC_011353.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D 2396114 rnd 6969465 rnd Escherichia coli O157:H7 str. EC4115 ribonuclease D YP_002270881.1 2394987 R 444450 CDS YP_002270882.1 209397101 6972304 complement(2396184..2397869) 1 NC_011353.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2397869 fadD 6972304 fadD Escherichia coli O157:H7 str. EC4115 long-chain-fatty-acid--CoA ligase YP_002270882.1 2396184 R 444450 CDS YP_002270883.1 209397301 6968049 complement(2398074..2398655) 1 NC_011353.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752; outer membrane protein Slp 2398655 slp 6968049 slp Escherichia coli O157:H7 str. EC4115 outer membrane protein Slp YP_002270883.1 2398074 R 444450 CDS YP_002270884.1 209400525 6968262 complement(2398695..2399390) 1 NC_011353.1 identified by match to protein family HMM PF00814; glycoprotease family protein 2399390 6968262 ECH74115_2534 Escherichia coli O157:H7 str. EC4115 glycoprotease family protein YP_002270884.1 2398695 R 444450 CDS YP_002270885.1 209396774 6971732 complement(2399448..2401358) 1 NC_011353.1 hypothetical protein 2401358 6971732 ECH74115_2535 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270885.1 2399448 R 444450 CDS YP_002270886.1 209400032 6967703 2401490..2401834 1 NC_011353.1 identified by match to protein family HMM PF01042; endoribonuclease L-PSP family protein 2401834 6967703 ECH74115_2536 Escherichia coli O157:H7 str. EC4115 endoribonuclease L-PSP family protein YP_002270886.1 2401490 D 444450 CDS YP_002270887.1 209398250 6971207 complement(2401868..2401999) 1 NC_011353.1 identified by glimmer; hypothetical protein 2401999 6971207 ECH74115_2537 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270887.1 2401868 R 444450 CDS YP_002270888.1 209396195 6969282 complement(2401984..2402100) 1 NC_011353.1 identified by glimmer; hypothetical protein 2402100 6969282 ECH74115_2538 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270888.1 2401984 R 444450 CDS YP_002270889.1 209399232 6967082 2402256..2402555 1 NC_011353.1 identified by match to protein family HMM PF08986; hypothetical protein 2402555 6967082 ECH74115_2539 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270889.1 2402256 D 444450 CDS YP_002270890.1 209397171 6970343 complement(2402675..2402854) 1 NC_011353.1 identified by match to protein family HMM PF03701; hypothetical protein 2402854 6970343 ECH74115_2540 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270890.1 2402675 R 444450 CDS YP_002270891.1 209399624 6968124 2402928..2404289 1 NC_011353.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553; aminodeoxychorismate synthase 2404289 pabB 6968124 pabB Escherichia coli O157:H7 str. EC4115 aminodeoxychorismate synthase YP_002270891.1 2402928 D 444450 CDS YP_002270892.1 209397357 6970768 2404293..2404871 1 NC_011353.1 identified by match to protein family HMM PF00293; hypothetical protein 2404871 6970768 ECH74115_2542 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270892.1 2404293 D 444450 CDS YP_002270893.1 209400418 6968324 2405055..2406419 1 NC_011353.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine ammonia-lyase 1 2406419 sdaA 6968324 sdaA Escherichia coli O157:H7 str. EC4115 L-serine ammonia-lyase 1 YP_002270893.1 2405055 D 444450 CDS YP_002270894.1 209400930 6971619 2406550..2408148 1 NC_011353.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 2408148 6971619 ECH74115_2544 Escherichia coli O157:H7 str. EC4115 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein YP_002270894.1 2406550 D 444450 CDS YP_002270895.1 209398900 6972167 complement(2408152..2409708) 1 NC_011353.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein 2409708 6972167 ECH74115_2545 Escherichia coli O157:H7 str. EC4115 TerC family/CBS/transporter associated domain-containing protein YP_002270895.1 2408152 R 444450 CDS YP_002270896.1 209399568 6969990 2410171..2411142 1 NC_011353.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854; PTS system mannose-specific transporter subunit IIAB 2411142 manX 6969990 manX Escherichia coli O157:H7 str. EC4115 PTS system mannose-specific transporter subunit IIAB YP_002270896.1 2410171 D 444450 CDS YP_002270897.1 209397846 6970706 2411205..2412005 1 NC_011353.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822; PTS system mannose-specific transporter subunit IIC 2412005 manY 6970706 manY Escherichia coli O157:H7 str. EC4115 PTS system mannose-specific transporter subunit IIC YP_002270897.1 2411205 D 444450 CDS YP_002270898.1 209395956 6968838 2412018..2412869 1 NC_011353.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2412869 manZ 6968838 manZ Escherichia coli O157:H7 str. EC4115 PTS system mannose-specific transporter subunit IID YP_002270898.1 2412018 D 444450 CDS YP_002270899.1 209396582 6966823 2412924..2413382 1 NC_011353.1 identified by match to protein family HMM PF06173; hypothetical protein 2413382 6966823 ECH74115_2549 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270899.1 2412924 D 444450 CDS YP_002270900.1 209400164 6967497 2413693..2413815 1 NC_011353.1 identified by glimmer; hypothetical protein 2413815 6967497 ECH74115_2551 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270900.1 2413693 D 444450 CDS YP_002270901.1 209398962 6971350 2413812..2414378 1 NC_011353.1 membrane protein YebN; hypothetical protein 2414378 6971350 ECH74115_2553 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270901.1 2413812 D 444450 CDS YP_002270902.1 209400676 6970057 complement(2414375..2415184) 1 NC_011353.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 2415184 rrmA 6970057 rrmA Escherichia coli O157:H7 str. EC4115 23S rRNA methyltransferase A YP_002270902.1 2414375 R 444450 CDS YP_002270903.1 209397128 6971895 complement(2415350..2415559) 1 NC_011353.1 identified by match to protein family HMM PF00313; cold shock-like protein CspC 2415559 cspC 6971895 cspC Escherichia coli O157:H7 str. EC4115 cold shock-like protein CspC YP_002270903.1 2415350 R 444450 CDS YP_002270904.1 209395972 6968077 complement(2415572..2415715) 1 NC_011353.1 hypothetical protein 2415715 6968077 ECH74115_2555 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270904.1 2415572 R 444450 CDS YP_002270905.1 209400036 6966841 complement(2416384..2416671) 1 NC_011353.1 hypothetical protein 2416671 6966841 ECH74115_2556 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270905.1 2416384 R 444450 CDS YP_002270906.1 209399562 6971211 complement(2416746..2416889) 1 NC_011353.1 hypothetical protein 2416889 6971211 ECH74115_2557 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270906.1 2416746 R 444450 CDS YP_002270907.1 209398976 6970700 2417049..2417288 1 NC_011353.1 hypothetical protein 2417288 6970700 ECH74115_2558 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270907.1 2417049 D 444450 CDS YP_002270908.1 209397812 6970075 complement(2417432..2418223) 1 NC_011353.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339; transcriptional regulator KdgR 2418223 kdgR 6970075 kdgR Escherichia coli O157:H7 str. EC4115 transcriptional regulator KdgR YP_002270908.1 2417432 R 444450 CDS YP_002270909.1 209397060 6968803 2418400..2419773 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2419773 6968803 ECH74115_2560 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002270909.1 2418400 D 444450 CDS YP_002270910.1 209396672 6968006 complement(2419819..2420700) 1 NC_011353.1 metalloprotease; heat shock protein HtpX 2420700 6968006 ECH74115_2561 Escherichia coli O157:H7 str. EC4115 heat shock protein HtpX YP_002270910.1 2419819 R 444450 CDS YP_002270911.1 209400608 6967593 complement(2420795..2420935) 1 NC_011353.1 identified by glimmer; hypothetical protein 2420935 6967593 ECH74115_2562 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270911.1 2420795 R 444450 CDS YP_002270912.1 209399862 6971820 complement(2420892..2422934) 1 NC_011353.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2422934 prc 6971820 prc Escherichia coli O157:H7 str. EC4115 carboxy-terminal protease YP_002270912.1 2420892 R 444450 CDS YP_002270913.1 209399115 6971021 complement(2422960..2423658) 1 NC_011353.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 2423658 proQ 6971021 proQ Escherichia coli O157:H7 str. EC4115 solute/DNA competence effector YP_002270913.1 2422960 R 444450 CDS YP_002270914.1 209397373 6970217 complement(2423755..2424252) 1 NC_011353.1 identified by match to protein family HMM PF01590; GAF domain-containing protein 2424252 6970217 ECH74115_2565 Escherichia coli O157:H7 str. EC4115 GAF domain-containing protein YP_002270914.1 2423755 R 444450 CDS YP_002270915.1 209398570 6968339 2424382..2425665 1 NC_011353.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155; PqiA family integral membrane protein 2425665 6968339 ECH74115_2566 Escherichia coli O157:H7 str. EC4115 PqiA family integral membrane protein YP_002270915.1 2424382 D 444450 CDS YP_002270916.1 209400762 6969631 2425628..2428267 1 NC_011353.1 identified by match to protein family HMM PF02470; mce-like protein 2428267 6969631 ECH74115_2567 Escherichia coli O157:H7 str. EC4115 mce-like protein YP_002270916.1 2425628 D 444450 CDS YP_002270917.1 209399709 6971987 2428348..2429787 1 NC_011353.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2429787 yebU 6971987 yebU Escherichia coli O157:H7 str. EC4115 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_002270917.1 2428348 D 444450 CDS YP_002270918.1 209396659 6970860 2429905..2430141 1 NC_011353.1 identified by match to protein family HMM PF07351; hypothetical protein 2430141 6970860 ECH74115_2569 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270918.1 2429905 D 444450 CDS YP_002270919.1 209397810 6967580 2430246..2430437 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 2430437 6967580 ECH74115_2570 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270919.1 2430246 D 444450 CDS YP_002270920.1 209397009 6968800 complement(2430438..2431094) 1 NC_011353.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 2431094 pphA 6968800 pphA Escherichia coli O157:H7 str. EC4115 serine/threonine protein phosphatase 1 YP_002270920.1 2430438 R 444450 CDS YP_002270921.1 209397388 6972297 complement(2431490..2431831) 1 NC_011353.1 hypothetical protein 2431831 6972297 ECH74115_2574 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270921.1 2431490 R 444450 CDS YP_002270922.1 209399623 6968354 complement(2431844..2432716) 1 NC_011353.1 identified by match to protein family HMM PF05425; copper resistance protein D 2432716 6968354 ECH74115_2575 Escherichia coli O157:H7 str. EC4115 copper resistance protein D YP_002270922.1 2431844 R 444450 CDS YP_002270923.1 209400706 6970767 complement(2432720..2433094) 1 NC_011353.1 identified by match to protein family HMM PF04234; hypothetical protein 2433094 6970767 ECH74115_2576 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270923.1 2432720 R 444450 CDS YP_002270924.1 209400710 6971929 2433233..2433463 1 NC_011353.1 identified by match to protein family HMM PF06440; DNA polymerase III subunit theta 2433463 holE 6971929 holE Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit theta YP_002270924.1 2433233 D 444450 CDS YP_002270925.1 209399166 6971933 2433565..2434221 1 NC_011353.1 identified by match to protein family HMM PF00795; hydrolase 2434221 6971933 ECH74115_2578 Escherichia coli O157:H7 str. EC4115 hydrolase YP_002270925.1 2433565 D 444450 CDS YP_002270926.1 209398184 6970274 2434245..2434907 1 NC_011353.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2434907 exoX 6970274 exoX Escherichia coli O157:H7 str. EC4115 exodeoxyribonuclease X YP_002270926.1 2434245 D 444450 CDS YP_002270927.1 209398588 6969210 complement(2434904..2436964) 1 NC_011353.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 2436964 prtB 6969210 prtB Escherichia coli O157:H7 str. EC4115 protease 2 YP_002270927.1 2434904 R 444450 CDS YP_002270928.1 209397073 6969649 complement(2437173..2437832) 1 NC_011353.1 identified by match to protein family HMM PF04391; hypothetical protein 2437832 6969649 ECH74115_2581 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270928.1 2437173 R 444450 CDS YP_002270929.1 209396926 6968019 complement(2438159..2438527) 1 NC_011353.1 secreted protein; unknown function; hypothetical protein 2438527 6968019 ECH74115_2582 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270929.1 2438159 R 444450 CDS YP_002270930.1 209396185 6967864 complement(2438582..2438872) 1 NC_011353.1 identified by match to protein family HMM PF07130; DNA damage-inducible protein YebG 2438872 6967864 ECH74115_2583 Escherichia coli O157:H7 str. EC4115 DNA damage-inducible protein YebG YP_002270930.1 2438582 R 444450 CDS YP_002270931.1 209400324 6967071 2439006..2440184 1 NC_011353.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2440184 purT 6967071 purT Escherichia coli O157:H7 str. EC4115 phosphoribosylglycinamide formyltransferase 2 YP_002270931.1 2439006 D 444450 CDS YP_002270932.1 209400265 6971520 complement(2440240..2440881) 1 NC_011353.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2440881 eda 6971520 eda Escherichia coli O157:H7 str. EC4115 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002270932.1 2440240 R 444450 CDS YP_002270933.1 209399326 6971458 complement(2440918..2442729) 1 NC_011353.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2442729 edd 6971458 edd Escherichia coli O157:H7 str. EC4115 phosphogluconate dehydratase YP_002270933.1 2440918 R 444450 CDS YP_002270934.1 209396330 6970446 complement(2442964..2444439) 1 NC_011353.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2444439 zwf 6970446 zwf Escherichia coli O157:H7 str. EC4115 glucose-6-phosphate 1-dehydrogenase YP_002270934.1 2442964 R 444450 CDS YP_002270935.1 209399722 6967227 complement(2444605..2444754) 1 NC_011353.1 hypothetical protein 2444754 6967227 ECH74115_2588 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270935.1 2444605 R 444450 CDS YP_002270936.1 209400498 6970875 2444777..2445646 1 NC_011353.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2445646 6970875 ECH74115_2589 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator HexR YP_002270936.1 2444777 D 444450 CDS YP_002270937.1 209397278 6971703 2445774..2447216 1 NC_011353.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2447216 pykA 6971703 pykA Escherichia coli O157:H7 str. EC4115 pyruvate kinase YP_002270937.1 2445774 D 444450 CDS YP_002270938.1 209397852 6968239 complement(2447347..2448318) 1 NC_011353.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2448318 msbB 6968239 msbB Escherichia coli O157:H7 str. EC4115 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002270938.1 2447347 R 444450 CDS YP_002270939.1 209396115 6968844 complement(2448438..2449760) 1 NC_011353.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525; hypothetical protein 2449760 6968844 ECH74115_2592 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270939.1 2448438 R 444450 CDS YP_002270940.1 209396677 6966995 complement(2449776..2450708) 1 NC_011353.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 2450708 znuA 6966995 znuA Escherichia coli O157:H7 str. EC4115 high-affinity zinc transporter periplasmic protein YP_002270940.1 2449776 R 444450 CDS YP_002270941.1 209400274 6967598 2450787..2451542 1 NC_011353.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2451542 znuC 6967598 znuC Escherichia coli O157:H7 str. EC4115 high-affinity zinc transporter ATPase YP_002270941.1 2450787 D 444450 CDS YP_002270942.1 209400842 6971467 2451539..2452324 1 NC_011353.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2452324 znuB 6971467 znuB Escherichia coli O157:H7 str. EC4115 high-affinity zinc transporter membrane protein YP_002270942.1 2451539 D 444450 CDS YP_002270943.1 209399063 6972073 complement(2452570..2453580) 1 NC_011353.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2453580 ruvB 6972073 ruvB Escherichia coli O157:H7 str. EC4115 Holliday junction DNA helicase RuvB YP_002270943.1 2452570 R 444450 CDS YP_002270944.1 209396228 6970165 complement(2453589..2454200) 1 NC_011353.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2454200 ruvA 6970165 ruvA Escherichia coli O157:H7 str. EC4115 Holliday junction DNA helicase RuvA YP_002270944.1 2453589 R 444450 CDS YP_002270945.1 209398122 6967118 2454475..2455077 1 NC_011353.1 identified by match to protein family HMM PF06520; hypothetical protein 2455077 6967118 ECH74115_2598 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270945.1 2454475 D 444450 CDS YP_002270946.1 209397411 6969142 complement(2455079..2455600) 1 NC_011353.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2455600 ruvC 6969142 ruvC Escherichia coli O157:H7 str. EC4115 Holliday junction resolvase YP_002270946.1 2455079 R 444450 CDS YP_002270947.1 209400343 6968379 complement(2455635..2456375) 1 NC_011353.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 2456375 6968379 ECH74115_2600 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270947.1 2455635 R 444450 CDS YP_002270948.1 209399929 6971540 complement(2456404..2456913) 1 NC_011353.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2456913 ntpA 6971540 ntpA Escherichia coli O157:H7 str. EC4115 dATP pyrophosphohydrolase YP_002270948.1 2456404 R 444450 CDS YP_002270949.1 209396974 6971094 complement(2456974..2458746) 1 NC_011353.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2458746 aspS 6971094 aspS Escherichia coli O157:H7 str. EC4115 aspartyl-tRNA synthetase YP_002270949.1 2456974 R 444450 CDS YP_002270950.1 209396237 6967914 2459056..2459622 1 NC_011353.1 identified by match to protein family HMM PF00857; hypothetical protein 2459622 6967914 ECH74115_2603 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270950.1 2459056 D 444450 CDS YP_002270951.1 209397353 6967128 2459619..2460437 1 NC_011353.1 identified by match to protein family HMM PF01904; hypothetical protein 2460437 6967128 ECH74115_2604 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270951.1 2459619 D 444450 CDS YP_002270952.1 209396949 6968320 2460490..2460885 1 NC_011353.1 inner membrane protein 2460885 6968320 ECH74115_2605 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002270952.1 2460490 D 444450 CDS YP_002270953.1 209399188 6967887 2460926..2461669 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740; methyltransferase 2461669 6967887 ECH74115_2606 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002270953.1 2460926 D 444450 CDS YP_002270954.1 209399461 6970296 2461666..2462637 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452; methyltransferase 2462637 6970296 ECH74115_2607 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002270954.1 2461666 D 444450 CDS YP_002270955.1 209400029 6970591 complement(2462802..2465231) 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; trimethylamine N-oxide reductase III subunit TorZ 2465231 torZ 6970591 torZ Escherichia coli O157:H7 str. EC4115 trimethylamine N-oxide reductase III subunit TorZ YP_002270955.1 2462802 R 444450 CDS YP_002270956.1 209400901 6971204 complement(2465256..2466356) 1 NC_011353.1 identified by match to protein family HMM PF03264; trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY 2466356 torY 6971204 torY Escherichia coli O157:H7 str. EC4115 trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY YP_002270956.1 2465256 R 444450 CDS YP_002270957.1 209396910 6972136 complement(2466744..2467490) 1 NC_011353.1 identified by match to protein family HMM PF03932; copper homeostasis protein CutC 2467490 cutC 6972136 cutC Escherichia coli O157:H7 str. EC4115 copper homeostasis protein CutC YP_002270957.1 2466744 R 444450 CDS YP_002270958.1 209399762 6967848 complement(2467504..2468076) 1 NC_011353.1 identified by match to protein family HMM PF06185; hypothetical protein 2468076 6967848 ECH74115_2611 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270958.1 2467504 R 444450 CDS YP_002270959.1 209397716 6970918 complement(2468139..2468252) 1 NC_011353.1 hypothetical protein 2468252 6970918 ECH74115_2612 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270959.1 2468139 R 444450 CDS YP_002270960.1 209395919 6968701 2468286..2470019 1 NC_011353.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2470019 argS 6968701 argS Escherichia coli O157:H7 str. EC4115 arginyl-tRNA synthetase YP_002270960.1 2468286 D 444450 CDS YP_002270961.1 209401004 6966786 2470196..2470684 1 NC_011353.1 identified by match to protein family HMM PF07007; hypothetical protein 2470684 6966786 ECH74115_2614 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270961.1 2470196 D 444450 CDS YP_002270962.1 209398722 6972246 complement(2470804..2471040) 1 NC_011353.1 identified by match to protein family HMM PF06366; flagellar protein FlhE 2471040 flhE 6972246 flhE Escherichia coli O157:H7 str. EC4115 flagellar protein FlhE YP_002270962.1 2470804 R 444450 CDS YP_002270963.1 209396703 6969794 complement(2471196..2473274) 1 NC_011353.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2473274 flhA 6969794 flhA Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FlhA YP_002270963.1 2471196 R 444450 CDS YP_002270964.1 209400586 6967627 complement(2473267..2474415) 1 NC_011353.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2474415 flhB 6967627 flhB Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FlhB YP_002270964.1 2473267 R 444450 CDS YP_002270965.1 209399071 6968288 complement(2474617..2475261) 1 NC_011353.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 2475261 cheZ 6968288 cheZ Escherichia coli O157:H7 str. EC4115 chemotaxis regulator CheZ YP_002270965.1 2474617 R 444450 CDS YP_002270966.1 209396417 6970173 complement(2475272..2475661) 1 NC_011353.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 2475661 cheY 6970173 cheY Escherichia coli O157:H7 str. EC4115 chemotaxis regulatory protein CheY YP_002270966.1 2475272 R 444450 CDS YP_002270967.1 209395819 6967324 complement(2475676..2476725) 1 NC_011353.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2476725 cheB 6967324 cheB Escherichia coli O157:H7 str. EC4115 chemotaxis-specific methylesterase YP_002270967.1 2475676 R 444450 CDS YP_002270968.1 209400250 6966676 complement(2476728..2477588) 1 NC_011353.1 methylates the MCP; chemotaxis methyltransferase CheR 2477588 cheR 6966676 cheR Escherichia coli O157:H7 str. EC4115 chemotaxis methyltransferase CheR YP_002270968.1 2476728 R 444450 CDS YP_002270969.1 209396965 6971441 complement(2477607..2479208) 1 NC_011353.1 mediates taxis toward dipeptides; methyl-accepting protein IV 2479208 tap 6971441 tap Escherichia coli O157:H7 str. EC4115 methyl-accepting protein IV YP_002270969.1 2477607 R 444450 CDS YP_002270970.1 209399651 6967904 complement(2479254..2480915) 1 NC_011353.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein II 2480915 tar 6967904 tar Escherichia coli O157:H7 str. EC4115 methyl-accepting chemotaxis protein II YP_002270970.1 2479254 R 444450 CDS YP_002270971.1 209398753 6972306 complement(2481058..2481561) 1 NC_011353.1 identified by match to protein family HMM PF01584; purine-binding chemotaxis protein 2481561 cheW 6972306 cheW Escherichia coli O157:H7 str. EC4115 purine-binding chemotaxis protein YP_002270971.1 2481058 R 444450 CDS YP_002270972.1 209397867 6969829 complement(2481582..2483540) 1 NC_011353.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 2483540 cheA 6969829 cheA Escherichia coli O157:H7 str. EC4115 chemotaxis protein CheA YP_002270972.1 2481582 R 444450 CDS YP_002270973.1 209397424 6968859 complement(2483551..2484477) 1 NC_011353.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2484477 motB 6968859 motB Escherichia coli O157:H7 str. EC4115 flagellar motor protein MotB YP_002270973.1 2483551 R 444450 CDS YP_002270974.1 209396503 6968393 complement(2484474..2485361) 1 NC_011353.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2485361 motA 6968393 motA Escherichia coli O157:H7 str. EC4115 flagellar motor protein MotA YP_002270974.1 2484474 R 444450 CDS YP_002270975.1 209396245 6967415 complement(2485488..2486066) 1 NC_011353.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 2486066 flhC 6967415 flhC Escherichia coli O157:H7 str. EC4115 transcriptional activator FlhC YP_002270975.1 2485488 R 444450 CDS YP_002270976.1 209398587 6967137 complement(2486069..2486419) 1 NC_011353.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2486419 flhD 6967137 flhD Escherichia coli O157:H7 str. EC4115 transcriptional activator FlhD YP_002270976.1 2486069 R 444450 CDS YP_002270977.1 209400371 6969648 2487199..2487627 1 NC_011353.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2487627 uspC 6969648 uspC Escherichia coli O157:H7 str. EC4115 universal stress protein UspC YP_002270977.1 2487199 D 444450 CDS YP_002270978.1 209398057 6971571 complement(2487634..2489058) 1 NC_011353.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400; trehalose-6-phosphate synthase 2489058 otsA 6971571 otsA Escherichia coli O157:H7 str. EC4115 trehalose-6-phosphate synthase YP_002270978.1 2487634 R 444450 CDS YP_002270979.1 209397503 6969072 complement(2489033..2489833) 1 NC_011353.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2489833 otsB 6969072 otsB Escherichia coli O157:H7 str. EC4115 trehalose-6-phosphate phosphatase YP_002270979.1 2489033 R 444450 CDS YP_002270980.1 209396335 6968475 complement(2490000..2490986) 1 NC_011353.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2490986 araH 6968475 araH Escherichia coli O157:H7 str. EC4115 L-arabinose transporter permease YP_002270980.1 2490000 R 444450 CDS YP_002270981.1 209398046 6967234 complement(2491001..2492515) 1 NC_011353.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2492515 araG 6967234 araG Escherichia coli O157:H7 str. EC4115 L-arabinose transporter ATP-binding protein YP_002270981.1 2491001 R 444450 CDS YP_002270982.1 209399828 6969060 complement(2492585..2493574) 1 NC_011353.1 identified by match to protein family HMM PF00532; L-arabinose ABC transporter substrate-binding protein 2493574 araF 6969060 araF Escherichia coli O157:H7 str. EC4115 L-arabinose ABC transporter substrate-binding protein YP_002270982.1 2492585 R 444450 CDS YP_002270983.1 209398984 6970985 2494371..2494874 1 NC_011353.1 identified by match to protein family HMM PF00210; ferritin family protein 2494874 6970985 ECH74115_2638 Escherichia coli O157:H7 str. EC4115 ferritin family protein YP_002270983.1 2494371 D 444450 CDS YP_002270984.1 209397935 6970083 complement(2494954..2495205) 1 NC_011353.1 hypothetical protein 2495205 6970083 ECH74115_2639 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270984.1 2494954 R 444450 CDS YP_002270985.1 209397192 6968936 2495317..2495463 1 NC_011353.1 identified by glimmer; hypothetical protein 2495463 6968936 ECH74115_2640 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270985.1 2495317 D 444450 CDS YP_002270986.1 209400632 6968148 complement(2495552..2495695) 1 NC_011353.1 identified by glimmer; hypothetical protein 2495695 6968148 ECH74115_2641 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270986.1 2495552 R 444450 CDS YP_002270987.1 209399890 6971846 2495737..2495991 1 NC_011353.1 lipoprotein 2495991 6971846 ECH74115_2642 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002270987.1 2495737 D 444450 CDS YP_002270988.1 209399145 6971052 complement(2495997..2496137) 1 NC_011353.1 identified by glimmer; hypothetical protein 2496137 6971052 ECH74115_2643 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270988.1 2495997 R 444450 CDS YP_002270989.1 209398403 6970252 2496162..2496659 1 NC_011353.1 cytoplasmic iron storage protein; ferritin 2496659 ftnA 6970252 ftnA Escherichia coli O157:H7 str. EC4115 ferritin YP_002270989.1 2496162 D 444450 CDS YP_002270990.1 209397342 6969449 complement(2496696..2496935) 1 NC_011353.1 hypothetical protein 2496935 6969449 ECH74115_2645 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270990.1 2496696 R 444450 CDS YP_002270991.1 209399595 6968309 complement(2497075..2497173) 1 NC_011353.1 identified by glimmer; hypothetical protein 2497173 6968309 ECH74115_2646 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270991.1 2497075 R 444450 CDS YP_002270992.1 209395924 6970736 2497127..2498338 1 NC_011353.1 identified by match to protein family HMM PF03222; match to protein family HMM TIGR00837; tyrosine-specific transport protein 2498338 tyrP 6970736 tyrP Escherichia coli O157:H7 str. EC4115 tyrosine-specific transport protein YP_002270992.1 2497127 D 444450 CDS YP_002270993.1 209400994 6966791 complement(2498400..2499065) 1 NC_011353.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292; hypothetical protein 2499065 6966791 ECH74115_2648 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270993.1 2498400 R 444450 CDS YP_002270994.1 209395701 6972236 complement(2499422..2500423) 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase family protein 2500423 6972236 ECH74115_2649 Escherichia coli O157:H7 str. EC4115 integrase family protein YP_002270994.1 2499422 R 444450 CDS YP_002270995.1 209396557 6966555 complement(2500429..2500776) 1 NC_011353.1 hypothetical protein 2500776 6966555 ECH74115_2650 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270995.1 2500429 R 444450 CDS YP_002270996.1 209397296 6967471 complement(2500806..2501456) 1 NC_011353.1 hypothetical protein 2501456 6967471 ECH74115_2651 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270996.1 2500806 R 444450 CDS YP_002270997.1 209396099 6968257 complement(2501472..2501732) 1 NC_011353.1 transcriptional regulator 2501732 6968257 ECH74115_2652 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002270997.1 2501472 R 444450 CDS YP_002270998.1 209399491 6966978 2502175..2502378 1 NC_011353.1 DNA-binding protein 2502378 6966978 ECH74115_2653 Escherichia coli O157:H7 str. EC4115 DNA-binding protein YP_002270998.1 2502175 D 444450 CDS YP_002270999.1 209397554 6970625 2502400..2502750 1 NC_011353.1 hypothetical protein 2502750 6970625 ECH74115_2654 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002270999.1 2502400 D 444450 CDS YP_002271000.1 209399015 6968529 2502761..2503039 1 NC_011353.1 hypothetical protein 2503039 6968529 ECH74115_2655 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271000.1 2502761 D 444450 CDS YP_002271001.1 209397086 6970115 2503051..2503293 1 NC_011353.1 hypothetical protein 2503293 6970115 ECH74115_2656 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271001.1 2503051 D 444450 CDS YP_002271002.1 209398824 6968032 2503290..2503403 1 NC_011353.1 identified by glimmer; hypothetical protein 2503403 6968032 ECH74115_2657 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271002.1 2503290 D 444450 CDS YP_002271003.1 209397046 6969907 2503496..2503912 1 NC_011353.1 hypothetical protein 2503912 6969907 ECH74115_2658 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271003.1 2503496 D 444450 CDS YP_002271004.1 209400307 6967992 2503936..2504139 1 NC_011353.1 hypothetical protein 2504139 6967992 ECH74115_2659 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271004.1 2503936 D 444450 CDS YP_002271005.1 209399560 6971502 2504399..2504698 1 NC_011353.1 hypothetical protein 2504698 6971502 ECH74115_2660 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271005.1 2504399 D 444450 CDS YP_002271006.1 209396149 6970698 2505021..2505251 1 NC_011353.1 hypothetical protein 2505251 6970698 ECH74115_2661 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271006.1 2505021 D 444450 CDS YP_002271007.1 209400610 6967032 2505324..2505689 1 NC_011353.1 hypothetical protein 2505689 6967032 ECH74115_2662 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271007.1 2505324 D 444450 CDS YP_002271008.1 209397309 6971822 2505696..2508518 1 NC_011353.1 identified by match to protein family HMM PF05840; bacteriophage replication gene A protein 2508518 6971822 ECH74115_2663 Escherichia coli O157:H7 str. EC4115 bacteriophage replication gene A protein YP_002271008.1 2505696 D 444450 CDS YP_002271009.1 209396461 6968271 2508595..2509554 1 NC_011353.1 identified by match to protein family HMM PF06406; plasmid segregation protein ParM 2509554 6968271 ECH74115_2664 Escherichia coli O157:H7 str. EC4115 plasmid segregation protein ParM YP_002271009.1 2508595 D 444450 CDS YP_002271010.1 209397183 6967372 complement(2509893..2510582) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; transposase 2510582 6967372 ECH74115_2665 Escherichia coli O157:H7 str. EC4115 transposase YP_002271010.1 2509893 R 444450 CDS YP_002271011.1 209396455 6968137 complement(2510582..2510908) 1 NC_011353.1 overlaps another CDS with the same product name; IS629, transposase orfA 2510908 6968137 ECH74115_2666 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271011.1 2510582 R 444450 CDS YP_002271012.1 209398811 6967366 2511079..2511495 1 NC_011353.1 identified by match to protein family HMM PF02413; tail fiber assembly protein-like protein 2511495 6967366 ECH74115_2667 Escherichia coli O157:H7 str. EC4115 tail fiber assembly protein-like protein YP_002271012.1 2511079 D 444450 CDS YP_002271013.1 209397151 6969891 complement(2511539..2512015) 1 NC_011353.1 identified by match to protein family HMM PF00132; serine acetlyltransferase of prophage CP-933T 2512015 6969891 ECH74115_2668 Escherichia coli O157:H7 str. EC4115 serine acetlyltransferase of prophage CP-933T YP_002271013.1 2511539 R 444450 CDS YP_002271014.1 209396900 6968103 complement(2512268..2512756) 1 NC_011353.1 identified by match to protein family HMM PF06995; P2 GpU family protein 2512756 6968103 ECH74115_2669 Escherichia coli O157:H7 str. EC4115 P2 GpU family protein YP_002271014.1 2512268 R 444450 CDS YP_002271015.1 209400135 6971898 complement(2515559..2515714) 1 NC_011353.1 identified by match to protein family HMM PF06528; phage tail protein, P2 GpE family 2515714 6971898 ECH74115_2672 Escherichia coli O157:H7 str. EC4115 phage tail protein, P2 GpE family YP_002271015.1 2515559 R 444450 CDS YP_002271016.1 209399879 6971321 complement(2515723..2516088) 1 NC_011353.1 identified by match to protein family HMM PF06158; phage tail protein E 2516088 6971321 ECH74115_2673 Escherichia coli O157:H7 str. EC4115 phage tail protein E YP_002271016.1 2515723 R 444450 CDS YP_002271017.1 209399311 6971040 complement(2516143..2516655) 1 NC_011353.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611; phage major tail tube protein 2516655 6971040 ECH74115_2674 Escherichia coli O157:H7 str. EC4115 phage major tail tube protein YP_002271017.1 2516143 R 444450 CDS YP_002271018.1 209399284 6970428 complement(2516655..2517839) 1 NC_011353.1 identified by match to protein family HMM PF04984; phage tail sheath protein 2517839 6970428 ECH74115_2675 Escherichia coli O157:H7 str. EC4115 phage tail sheath protein YP_002271018.1 2516655 R 444450 CDS YP_002271019.1 209398146 6970400 2517819..2517950 1 NC_011353.1 identified by glimmer; hypothetical protein 2517950 6970400 ECH74115_2676 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271019.1 2517819 D 444450 CDS YP_002271020.1 209397947 6969169 2517997..2518320 1 NC_011353.1 tail protein 2518320 6969169 ECH74115_2678 Escherichia coli O157:H7 str. EC4115 tail protein YP_002271020.1 2517997 D 444450 CDS YP_002271021.1 209397386 6968950 complement(2518271..2519335) 1 NC_011353.1 identified by match to protein family HMM PF00665; transposase InsI for insertion sequence element IS30B/C/D 2519335 6968950 ECH74115_2677 Escherichia coli O157:H7 str. EC4115 transposase InsI for insertion sequence element IS30B/C/D YP_002271021.1 2518271 R 444450 CDS YP_002271022.1 209398757 6968352 2519297..2519623 1 NC_011353.1 overlaps another CDS with the same product name; IS629, transposase orfA 2519623 6968352 ECH74115_2679 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271022.1 2519297 D 444450 CDS YP_002271023.1 209399498 6969834 2519623..2520510 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2520510 6969834 ECH74115_2680 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271023.1 2519623 D 444450 CDS YP_002271024.1 209400207 6972357 complement(2522150..2522698) 1 NC_011353.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; phosphatidylglycerophosphate synthetase 2522698 pgsA 6972357 pgsA Escherichia coli O157:H7 str. EC4115 phosphatidylglycerophosphate synthetase YP_002271024.1 2522150 R 444450 CDS YP_002271025.1 209400940 6971395 complement(2522755..2524587) 1 NC_011353.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2524587 uvrC 6971395 uvrC Escherichia coli O157:H7 str. EC4115 excinuclease ABC subunit C YP_002271025.1 2522755 R 444450 CDS YP_002271026.1 209396376 6972177 complement(2524584..2525240) 1 NC_011353.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2525240 uvrY 6972177 uvrY Escherichia coli O157:H7 str. EC4115 response regulator YP_002271026.1 2524584 R 444450 CDS YP_002271027.1 209397111 6967281 2525382..2525498 1 NC_011353.1 identified by glimmer; hypothetical protein 2525498 6967281 ECH74115_2687 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271027.1 2525382 D 444450 CDS YP_002271028.1 209398013 6968060 2525536..2525712 1 NC_011353.1 identified by glimmer; hypothetical protein 2525712 6968060 ECH74115_2688 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271028.1 2525536 D 444450 CDS YP_002271029.1 209398710 6969026 2525699..2525923 1 NC_011353.1 hypothetical protein 2525923 6969026 ECH74115_2689 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271029.1 2525699 D 444450 CDS YP_002271030.1 209399275 6969782 complement(2525991..2526713) 1 NC_011353.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2526713 sdiA 6969782 sdiA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator SdiA YP_002271030.1 2525991 R 444450 CDS YP_002271031.1 209397719 6970391 complement(2526943..2527695) 1 NC_011353.1 identified by match to protein family HMM PF00005; amino-acid ABC transporter ATP-binding protein YecC 2527695 yecC 6970391 yecC Escherichia coli O157:H7 str. EC4115 amino-acid ABC transporter ATP-binding protein YecC YP_002271031.1 2526943 R 444450 CDS YP_002271032.1 209397535 6968704 complement(2527692..2528360) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; L-cystine ABC transporter permease 2528360 6968704 ECH74115_2692 Escherichia coli O157:H7 str. EC4115 L-cystine ABC transporter permease YP_002271032.1 2527692 R 444450 CDS YP_002271033.1 209400168 6968508 complement(2528375..2529361) 1 NC_011353.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2529361 dcyD 6968508 dcyD Escherichia coli O157:H7 str. EC4115 D-cysteine desulfhydrase YP_002271033.1 2528375 R 444450 CDS YP_002271034.1 209396748 6971355 complement(2529466..2530266) 1 NC_011353.1 identified by match to protein family HMM PF00497; cystine transporter subunit 2530266 fliY 6971355 fliY Escherichia coli O157:H7 str. EC4115 cystine transporter subunit YP_002271034.1 2529466 R 444450 CDS YP_002271035.1 209400649 6967674 complement(2530354..2530905) 1 NC_011353.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2530905 6967674 ECH74115_2695 Escherichia coli O157:H7 str. EC4115 flagella biosynthesis protein FliZ YP_002271035.1 2530354 R 444450 CDS YP_002271036.1 209399914 6971865 complement(2530951..2531670) 1 NC_011353.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2531670 fliA 6971865 fliA Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis sigma factor YP_002271036.1 2530951 R 444450 CDS YP_002271037.1 209397238 6971078 2531744..2531863 1 NC_011353.1 identified by glimmer; hypothetical protein 2531863 6971078 ECH74115_2697 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271037.1 2531744 D 444450 CDS YP_002271038.1 209399146 6968196 complement(2531990..2533747) 1 NC_011353.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2533747 6968196 ECH74115_2698 Escherichia coli O157:H7 str. EC4115 flagellin YP_002271038.1 2531990 R 444450 CDS YP_002271039.1 209395702 6970253 2534013..2535410 1 NC_011353.1 involved in flagellin assembly; flagellar capping protein 2535410 fliD 6970253 fliD Escherichia coli O157:H7 str. EC4115 flagellar capping protein YP_002271039.1 2534013 D 444450 CDS YP_002271040.1 209396257 6966556 2535435..2535845 1 NC_011353.1 flagellin specific chaperone; flagellar protein FliS 2535845 fliS 6966556 fliS Escherichia coli O157:H7 str. EC4115 flagellar protein FliS YP_002271040.1 2535435 D 444450 CDS YP_002271041.1 209399299 6967150 2535845..2536210 1 NC_011353.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2536210 fliT 6967150 fliT Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FliT YP_002271041.1 2535845 D 444450 CDS YP_002271042.1 209398533 6970415 2536288..2537775 1 NC_011353.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2537775 amyA 6970415 amyA Escherichia coli O157:H7 str. EC4115 alpha-amylase YP_002271042.1 2536288 D 444450 CDS YP_002271043.1 209397269 6969592 complement(2537809..2538222) 1 NC_011353.1 hypothetical protein 2538222 6969592 ECH74115_2703 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271043.1 2537809 R 444450 CDS YP_002271044.1 209399347 6968229 2538409..2539614 1 NC_011353.1 identified by match to protein family HMM PF04143; inner membrane protein 2539614 6968229 ECH74115_2704 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002271044.1 2538409 D 444450 CDS YP_002271045.1 209396244 6970468 2539611..2539844 1 NC_011353.1 identified by match to protein family HMM PF01206; hypothetical protein 2539844 6970468 ECH74115_2705 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271045.1 2539611 D 444450 CDS YP_002271046.1 209398329 6967136 2539953..2540621 1 NC_011353.1 identified by match to protein family HMM PF02586; hypothetical protein 2540621 6967136 ECH74115_2706 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271046.1 2539953 D 444450 CDS YP_002271047.1 209398471 6969368 2540732..2541211 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2541211 6969368 ECH74115_2707 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002271047.1 2540732 D 444450 CDS YP_002271048.1 209397909 6969526 complement(2541349..2542488) 1 NC_011353.1 identified by glimmer; hypothetical protein 2542488 6969526 ECH74115_2708 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271048.1 2541349 R 444450 CDS YP_002271049.1 209399338 6968907 2542870..2543169 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2543169 6968907 ECH74115_2710 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002271049.1 2542870 D 444450 CDS YP_002271050.1 209399913 6970458 complement(2543143..2543259) 1 NC_011353.1 identified by glimmer; hypothetical protein 2543259 6970458 ECH74115_2709 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271050.1 2543143 R 444450 CDS YP_002271051.1 209397973 6971077 complement(2543307..2544446) 1 NC_011353.1 identified by glimmer; hypothetical protein 2544446 6971077 ECH74115_2711 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271051.1 2543307 R 444450 CDS YP_002271052.1 209396041 6968982 complement(2544795..2545109) 1 NC_011353.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2545109 fliE 6968982 fliE Escherichia coli O157:H7 str. EC4115 flagellar hook-basal body protein FliE YP_002271052.1 2544795 R 444450 CDS YP_002271053.1 209397541 6966917 complement(2545154..2545303) 1 NC_011353.1 hypothetical protein 2545303 6966917 ECH74115_2713 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271053.1 2545154 R 444450 CDS YP_002271054.1 209395809 6968515 2545324..2546982 1 NC_011353.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2546982 fliF 6968515 fliF Escherichia coli O157:H7 str. EC4115 flagellar MS-ring protein YP_002271054.1 2545324 D 444450 CDS YP_002271055.1 209396112 6966665 2546975..2547970 1 NC_011353.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2547970 fliG 6966665 fliG Escherichia coli O157:H7 str. EC4115 flagellar motor switch protein G YP_002271055.1 2546975 D 444450 CDS YP_002271056.1 209396710 6966992 2547963..2548649 1 NC_011353.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2548649 fliH 6966992 fliH Escherichia coli O157:H7 str. EC4115 flagellar assembly protein H YP_002271056.1 2547963 D 444450 CDS YP_002271057.1 209400005 6967634 2548711..2550084 1 NC_011353.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2550084 fliI 6967634 fliI Escherichia coli O157:H7 str. EC4115 flagellum-specific ATP synthase YP_002271057.1 2548711 D 444450 CDS YP_002271058.1 209400846 6971178 2550103..2550546 1 NC_011353.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2550546 fliJ 6971178 fliJ Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis chaperone YP_002271058.1 2550103 D 444450 CDS YP_002271059.1 209398445 6972077 2550543..2551670 1 NC_011353.1 identified by match to protein family HMM PF02120; flagellar hook-length control protein 2551670 fliK 6972077 fliK Escherichia coli O157:H7 str. EC4115 flagellar hook-length control protein YP_002271059.1 2550543 D 444450 CDS YP_002271060.1 209399307 6969497 2551775..2552239 1 NC_011353.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2552239 fliL 6969497 fliL Escherichia coli O157:H7 str. EC4115 flagellar basal body-associated protein FliL YP_002271060.1 2551775 D 444450 CDS YP_002271061.1 209396357 6970424 2552244..2553248 1 NC_011353.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2553248 fliM 6970424 fliM Escherichia coli O157:H7 str. EC4115 flagellar motor switch protein FliM YP_002271061.1 2552244 D 444450 CDS YP_002271062.1 209396964 6967259 2553245..2553658 1 NC_011353.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2553658 fliN 6967259 fliN Escherichia coli O157:H7 str. EC4115 flagellar motor switch protein FliN YP_002271062.1 2553245 D 444450 CDS YP_002271063.1 209400279 6967903 complement(2553621..2553743) 1 NC_011353.1 identified by glimmer; hypothetical protein 2553743 6967903 ECH74115_2722 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271063.1 2553621 R 444450 CDS YP_002271064.1 209400251 6971472 2553721..2554026 1 NC_011353.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2554026 fliO 6971472 fliO Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FliO YP_002271064.1 2553721 D 444450 CDS YP_002271065.1 209400543 6971442 2554026..2554763 1 NC_011353.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2554763 fliP 6971442 fliP Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FliP YP_002271065.1 2554026 D 444450 CDS YP_002271066.1 209398388 6971751 2554773..2555042 1 NC_011353.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2555042 fliQ 6971751 fliQ Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FliQ YP_002271066.1 2554773 D 444450 CDS YP_002271067.1 209399396 6969432 2555050..2555835 1 NC_011353.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2555835 fliR 6969432 fliR Escherichia coli O157:H7 str. EC4115 flagellar biosynthesis protein FliR YP_002271067.1 2555050 D 444450 CDS YP_002271068.1 209399201 6970521 2556125..2556748 1 NC_011353.1 identified by match to protein family HMM PF00196; colanic acid capsular biosynthesis activation protein A 2556748 rcsA 6970521 rcsA Escherichia coli O157:H7 str. EC4115 colanic acid capsular biosynthesis activation protein A YP_002271068.1 2556125 D 444450 CDS YP_002271069.1 209398242 6970309 complement(2556792..2556980) 1 NC_011353.1 hypothetical protein 2556980 6970309 ECH74115_2729 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271069.1 2556792 R 444450 CDS YP_002271070.1 209396167 6969274 2557143..2557370 1 NC_011353.1 hypothetical protein 2557370 6969274 ECH74115_2730 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271070.1 2557143 D 444450 CDS YP_002271071.1 209397957 6972312 2557668..2558483 1 NC_011353.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2558483 6972312 ECH74115_2733 Escherichia coli O157:H7 str. EC4115 mannosyl-3-phosphoglycerate phosphatase YP_002271071.1 2557668 D 444450 CDS YP_002271072.1 209398052 6968962 complement(2558480..2560174) 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2560174 6968962 ECH74115_2732 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002271072.1 2558480 R 444450 CDS YP_002271073.1 209396454 6966730 complement(2560606..2561523) 1 NC_011353.1 identified by match to protein family HMM PF05661; hypothetical protein 2561523 6966730 ECH74115_2735 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271073.1 2560606 R 444450 CDS YP_002271074.1 209400853 6967365 2561696..2562616 1 NC_011353.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; hypothetical protein 2562616 6967365 ECH74115_2737 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271074.1 2561696 D 444450 CDS YP_002271075.1 209399672 6972084 complement(2562605..2563075) 1 NC_011353.1 identified by match to protein family HMM PF03852; match to protein family HMM TIGR00632; very short patch repair protein 2563075 vsr 6972084 vsr Escherichia coli O157:H7 str. EC4115 very short patch repair protein YP_002271075.1 2562605 R 444450 CDS YP_002271076.1 209400193 6970819 complement(2563056..2564474) 1 NC_011353.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; DNA cytosine methylase 2564474 dcm 6970819 dcm Escherichia coli O157:H7 str. EC4115 DNA cytosine methylase YP_002271076.1 2563056 R 444450 CDS YP_002271077.1 209400796 6971380 complement(2564541..2565236) 1 NC_011353.1 identified by match to protein family HMM PF01966; hypothetical protein 2565236 6971380 ECH74115_2739 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271077.1 2564541 R 444450 CDS YP_002271078.1 209399531 6967124 complement(2567602..2567724) 1 NC_011353.1 identified by glimmer; hypothetical protein 2567724 6967124 ECH74115_2744 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271078.1 2567602 R 444450 CDS YP_002271079.1 209400122 6970667 2567821..2567964 1 NC_011353.1 identified by glimmer; hypothetical protein 2567964 6970667 ECH74115_2745 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271079.1 2567821 D 444450 CDS YP_002271080.1 209397833 6971307 2567985..2568836 1 NC_011353.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2568836 hchA 6971307 hchA Escherichia coli O157:H7 str. EC4115 chaperone protein HchA YP_002271080.1 2567985 D 444450 CDS YP_002271081.1 209398520 6968824 complement(2568944..2570302) 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; heavy metal sensor histidine kinase 2570302 6968824 ECH74115_2747 Escherichia coli O157:H7 str. EC4115 heavy metal sensor histidine kinase YP_002271081.1 2568944 R 444450 CDS YP_002271082.1 209398847 6969579 complement(2570302..2571003) 1 NC_011353.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2571003 6969579 ECH74115_2748 Escherichia coli O157:H7 str. EC4115 transcriptional regulatory protein YedW YP_002271082.1 2570302 R 444450 CDS YP_002271083.1 209398126 6969932 2571106..2571519 1 NC_011353.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962; transthyretin family protein 2571519 6969932 ECH74115_2749 Escherichia coli O157:H7 str. EC4115 transthyretin family protein YP_002271083.1 2571106 D 444450 CDS YP_002271084.1 209397989 6969147 2571627..2572631 1 NC_011353.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2572631 6969147 ECH74115_2750 Escherichia coli O157:H7 str. EC4115 sulfite oxidase subunit YedY YP_002271084.1 2571627 D 444450 CDS YP_002271085.1 209397254 6969000 2572632..2573267 1 NC_011353.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2573267 6969000 ECH74115_2751 Escherichia coli O157:H7 str. EC4115 sulfite oxidase subunit YedZ YP_002271085.1 2572632 D 444450 CDS YP_002271086.1 209399884 6968212 2573524..2574174 1 NC_011353.1 identified by match to protein family HMM PF09223; hypothetical protein 2574174 6968212 ECH74115_2752 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271086.1 2573524 D 444450 CDS YP_002271087.1 209400552 6971046 2574517..2575047 1 NC_011353.1 identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit 2575047 6971046 ECH74115_2753 Escherichia coli O157:H7 str. EC4115 nickel-dependent hydrogenase, b-type cytochrome subunit YP_002271087.1 2574517 D 444450 CDS YP_002271088.1 209396229 6971761 2576184..2576837 1 NC_011353.1 non-LEE-encoded effector EspJ 2576837 6971761 ECH74115_2754 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector EspJ YP_002271088.1 2576184 D 444450 CDS YP_002271089.1 209396853 6967119 complement(2577146..2577310) 1 NC_011353.1 identified by glimmer; hypothetical protein 2577310 6967119 ECH74115_2755 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271089.1 2577146 R 444450 CDS YP_002271090.1 209396484 6967786 2577465..2578175 1 NC_011353.1 tir-cytoskeleton coupling protein 2578175 6967786 ECH74115_2756 Escherichia coli O157:H7 str. EC4115 tir-cytoskeleton coupling protein YP_002271090.1 2577465 D 444450 CDS YP_002271091.1 209399740 6967396 complement(2578301..2578570) 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 2578570 6967396 ECH74115_2757 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002271091.1 2578301 R 444450 CDS YP_002271092.1 209400529 6970895 complement(2578572..2579891) 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; tail fiber protein 2579891 6970895 ECH74115_2758 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002271092.1 2578572 R 444450 CDS YP_002271093.1 209398556 6971736 2579198..2579662 1 NC_011353.1 hypothetical protein 2579662 6971736 ECH74115_2759 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271093.1 2579198 D 444450 CDS YP_002271094.1 209399504 6969616 2579821..2579949 1 NC_011353.1 hypothetical protein 2579949 6969616 ECH74115_2760 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271094.1 2579821 D 444450 CDS YP_002271095.1 209397600 6970639 complement(2579950..2580549) 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 2580549 6970639 ECH74115_2761 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002271095.1 2579950 R 444450 CDS YP_002271096.1 209398947 6968579 complement(2580617..2584096) 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 2584096 6968579 ECH74115_2762 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271096.1 2580617 R 444450 CDS YP_002271097.1 209399631 6970041 complement(2584172..2584291) 1 NC_011353.1 identified by glimmer; hypothetical protein 2584291 6970041 ECH74115_2763 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271097.1 2584172 R 444450 CDS YP_002271098.1 209400266 6970776 complement(2584337..2584915) 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 2584915 6970776 ECH74115_2764 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002271098.1 2584337 R 444450 CDS YP_002271099.1 209400864 6971459 complement(2584912..2585547) 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 2585547 6971459 ECH74115_2765 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002271099.1 2584912 R 444450 CDS YP_002271100.1 209398799 6972095 complement(2585666..2586364) 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 2586364 6972095 ECH74115_2766 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002271100.1 2585666 R 444450 CDS YP_002271101.1 209399388 6969878 complement(2586364..2586693) 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 2586693 6969878 ECH74115_2767 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002271101.1 2586364 R 444450 CDS YP_002271102.1 209397298 6970513 complement(2586690..2589269) 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 2589269 6970513 ECH74115_2768 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002271102.1 2586690 R 444450 CDS YP_002271103.1 209397895 6968259 complement(2589250..2589639) 1 NC_011353.1 identified by match to protein family HMM TIGR01715; phage tail assembly protein T 2589639 6968259 ECH74115_2769 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002271103.1 2589250 R 444450 CDS YP_002271104.1 209398196 6968893 complement(2589690..2590121) 1 NC_011353.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 2590121 6968893 ECH74115_2770 Escherichia coli O157:H7 str. EC4115 phage minor tail protein G YP_002271104.1 2589690 R 444450 CDS YP_002271105.1 209396429 6969224 complement(2590135..2590797) 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 2590797 6969224 ECH74115_2771 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002271105.1 2590135 R 444450 CDS YP_002271106.1 209396588 6967336 complement(2590857..2591123) 1 NC_011353.1 major head protein 2591123 6967336 ECH74115_2772 Escherichia coli O157:H7 str. EC4115 major head protein YP_002271106.1 2590857 R 444450 CDS YP_002271107.1 209395882 6967503 complement(2591181..2591528) 1 NC_011353.1 identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 2591528 6967503 ECH74115_2773 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda head decoration protein D YP_002271107.1 2591181 R 444450 CDS YP_002271108.1 209395709 6966746 complement(2591565..2593070) 1 NC_011353.1 identified by match to protein family HMM PF01343; head-tail preconnector protein GP5 2593070 6966746 ECH74115_2774 Escherichia coli O157:H7 str. EC4115 head-tail preconnector protein GP5 YP_002271108.1 2591565 R 444450 CDS YP_002271109.1 209397959 6966563 complement(2593060..2594652) 1 NC_011353.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 2594652 6966563 ECH74115_2775 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002271109.1 2593060 R 444450 CDS YP_002271110.1 209399513 6968964 complement(2594649..2594855) 1 NC_011353.1 identified by match to protein family HMM PF02831; gpW 2594855 6968964 ECH74115_2776 Escherichia coli O157:H7 str. EC4115 gpW YP_002271110.1 2594649 R 444450 CDS YP_002271111.1 209400934 6969837 complement(2596740..2597249) 1 NC_011353.1 terminase small subunit 2597249 6969837 ECH74115_2779 Escherichia coli O157:H7 str. EC4115 terminase small subunit YP_002271111.1 2596740 R 444450 CDS YP_002271112.1 209399851 6972171 2597704..2597868 1 NC_011353.1 hypothetical protein 2597868 6972171 ECH74115_2780 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271112.1 2597704 D 444450 CDS YP_002271113.1 209396706 6971009 2598267..2598380 1 NC_011353.1 hypothetical protein 2598380 6971009 ECH74115_2781 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271113.1 2598267 D 444450 CDS YP_002271114.1 209399677 6967630 complement(2598506..2598646) 1 NC_011353.1 hypothetical protein 2598646 6967630 ECH74115_2782 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271114.1 2598506 R 444450 CDS YP_002271115.1 209400452 6970826 complement(2598729..2599196) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 2599196 6970826 ECH74115_2783 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002271115.1 2598729 R 444450 CDS YP_002271116.1 209396218 6971657 complement(2599348..2599494) 1 NC_011353.1 hypothetical protein 2599494 6971657 ECH74115_2784 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271116.1 2599348 R 444450 CDS YP_002271117.1 209396957 6967107 complement(2599686..2600219) 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 2600219 6967107 ECH74115_2785 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002271117.1 2599686 R 444450 CDS YP_002271118.1 209397622 6967895 complement(2600270..2600614) 1 NC_011353.1 identified by match to protein family HMM PF07041; hypothetical protein 2600614 6967895 ECH74115_2786 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271118.1 2600270 R 444450 CDS YP_002271119.1 209398153 6968603 complement(2600619..2600825) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 2600825 6968603 ECH74115_2787 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271119.1 2600619 R 444450 CDS YP_002271120.1 209396954 6969176 2601145..2601471 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2601471 6969176 ECH74115_2788 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271120.1 2601145 D 444450 CDS YP_002271121.1 209397362 6967892 2601468..2602358 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2602358 6967892 ECH74115_2789 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271121.1 2601468 D 444450 CDS YP_002271122.1 209397280 6968329 complement(2602440..2604290) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 2604290 6968329 ECH74115_2790 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271122.1 2602440 R 444450 CDS YP_002271123.1 209400327 6968863 complement(2604604..2604771) 1 NC_011353.1 hypothetical protein 2604771 6968863 ECH74115_2792 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271123.1 2604604 R 444450 CDS YP_002271124.1 209395730 6972338 complement(2605677..2605799) 1 NC_011353.1 identified by glimmer; hypothetical protein 2605799 6972338 ECH74115_2797 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271124.1 2605677 R 444450 CDS YP_002271125.1 209398894 6966585 complement(2605830..2606519) 1 NC_011353.1 identified by match to protein family HMM PF06323; antitermination protein Q 2606519 6966585 ECH74115_2798 Escherichia coli O157:H7 str. EC4115 antitermination protein Q YP_002271125.1 2605830 R 444450 CDS YP_002271126.1 209400830 6969983 complement(2606516..2606875) 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease 2606875 6969983 ECH74115_2799 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease YP_002271126.1 2606516 R 444450 CDS YP_002271127.1 209399495 6972058 complement(2606888..2607937) 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 2607937 6972058 ECH74115_2800 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271127.1 2606888 R 444450 CDS YP_002271128.1 209398726 6970629 complement(2607939..2608298) 1 NC_011353.1 hypothetical protein 2608298 6970629 ECH74115_2801 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271128.1 2607939 R 444450 CDS YP_002271129.1 209397976 6969799 complement(2608784..2608933) 1 NC_011353.1 hypothetical protein 2608933 6969799 ECH74115_2802 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271129.1 2608784 R 444450 CDS YP_002271130.1 209397209 6968985 complement(2608998..2609561) 1 NC_011353.1 hypothetical protein 2609561 6968985 ECH74115_2803 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271130.1 2608998 R 444450 CDS YP_002271131.1 209399738 6968167 complement(2609688..2609999) 1 NC_011353.1 hypothetical protein 2609999 6968167 ECH74115_2804 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271131.1 2609688 R 444450 CDS YP_002271132.1 209397709 6970892 complement(2610181..2610537) 1 NC_011353.1 hypothetical protein 2610537 6970892 ECH74115_2805 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271132.1 2610181 R 444450 CDS YP_002271133.1 209396039 6968693 complement(2610780..2611478) 1 NC_011353.1 identified by match to protein family HMM PF07789; hypothetical protein 2611478 6968693 ECH74115_2806 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271133.1 2610780 R 444450 CDS YP_002271134.1 209396760 6966915 complement(2611513..2611935) 1 NC_011353.1 hypothetical protein 2611935 6966915 ECH74115_2807 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271134.1 2611513 R 444450 CDS YP_002271135.1 209397526 6967688 complement(2611967..2613004) 1 NC_011353.1 hypothetical protein 2613004 6967688 ECH74115_2808 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271135.1 2611967 R 444450 CDS YP_002271136.1 209398332 6968499 complement(2613073..2613498) 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 2613498 6968499 ECH74115_2809 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271136.1 2613073 R 444450 CDS YP_002271137.1 209400359 6969372 2613805..2614464 1 NC_011353.1 identified by match to protein family HMM PF00717; repressor protein 2614464 6969372 ECH74115_2810 Escherichia coli O157:H7 str. EC4115 repressor protein YP_002271137.1 2613805 D 444450 CDS YP_002271138.1 209398453 6971557 2614739..2614891 1 NC_011353.1 identified by match to protein family HMM PF07151; hypothetical protein 2614891 6971557 ECH74115_2811 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271138.1 2614739 D 444450 CDS YP_002271139.1 209399956 6967431 2615372..2615560 1 NC_011353.1 identified by match to protein family HMM PF05358; hypothetical protein 2615560 6967431 ECH74115_2813 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271139.1 2615372 D 444450 CDS YP_002271140.1 209397105 6971125 2615557..2615745 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 2615745 6971125 ECH74115_2814 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271140.1 2615557 D 444450 CDS YP_002271141.1 209395796 6968054 2615841..2618312 1 NC_011353.1 exonuclease family protein 2618312 6968054 ECH74115_2815 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002271141.1 2615841 D 444450 CDS YP_002271142.1 209399238 6966652 2618371..2618574 1 NC_011353.1 hypothetical protein 2618574 6966652 ECH74115_2816 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271142.1 2618371 D 444450 CDS YP_002271143.1 209399988 6970349 2618574..2619653 1 NC_011353.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 2619653 6970349 ECH74115_2817 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002271143.1 2618574 D 444450 CDS YP_002271144.1 209398254 6972425 2619845..2620642 1 NC_011353.1 identified by match to protein family HMM PF06167; Mlc titration factor MtfA 2620642 mtfA 6972425 mtfA Escherichia coli O157:H7 str. EC4115 Mlc titration factor MtfA YP_002271144.1 2619845 D 444450 CDS YP_002271145.1 209398677 6972374 2621252..2629114 1 NC_011353.1 identified by match to protein family HMM PF02369; hypothetical protein 2629114 6972374 ECH74115_2821 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271145.1 2621252 D 444450 CDS YP_002271146.1 209399119 6969747 complement(2629376..2630428) 1 NC_011353.1 hypothetical protein 2630428 6969747 ECH74115_2822 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271146.1 2629376 R 444450 CDS YP_002271147.1 209399883 6970221 2630742..2632058 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; shikimate transporter 2632058 shiA 6970221 shiA Escherichia coli O157:H7 str. EC4115 shikimate transporter YP_002271147.1 2630742 D 444450 CDS YP_002271148.1 209398270 6971044 2632160..2633614 1 NC_011353.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2633614 amn 6971044 amn Escherichia coli O157:H7 str. EC4115 AMP nucleosidase YP_002271148.1 2632160 D 444450 CDS YP_002271149.1 209399007 6969302 2633957..2634673 1 NC_011353.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 2634673 6969302 ECH74115_2825 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271149.1 2633957 D 444450 CDS YP_002271150.1 209396736 6970106 complement(2634764..2634886) 1 NC_011353.1 identified by glimmer; hypothetical protein 2634886 6970106 ECH74115_2826 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271150.1 2634764 R 444450 CDS YP_002271151.1 209395807 6967662 2634967..2635083 1 NC_011353.1 identified by glimmer; hypothetical protein 2635083 6967662 ECH74115_2827 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271151.1 2634967 D 444450 CDS YP_002271152.1 209399760 6972388 complement(2635299..2636753) 1 NC_011353.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; hypothetical protein 2636753 6972388 ECH74115_2829 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271152.1 2635299 R 444450 CDS YP_002271153.1 209396344 6972432 complement(2637060..2638010) 1 NC_011353.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2638010 cbl 6972432 cbl Escherichia coli O157:H7 str. EC4115 transcriptional regulator Cbl YP_002271153.1 2637060 R 444450 CDS YP_002271154.1 209398593 6967246 complement(2638112..2639029) 1 NC_011353.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2639029 nac 6967246 nac Escherichia coli O157:H7 str. EC4115 nitrogen assimilation transcriptional regulator YP_002271154.1 2638112 R 444450 CDS YP_002271155.1 209400490 6969654 2639217..2639333 1 NC_011353.1 identified by glimmer; hypothetical protein 2639333 6969654 ECH74115_2833 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271155.1 2639217 D 444450 CDS YP_002271156.1 209400843 6972402 complement(2639486..2640421) 1 NC_011353.1 identified by match to protein family HMM PF03734; hypothetical protein 2640421 6972402 ECH74115_2835 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271156.1 2639486 R 444450 CDS YP_002271157.1 209400225 6972074 complement(2640483..2641562) 1 NC_011353.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2641562 cobT 6972074 cobT Escherichia coli O157:H7 str. EC4115 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_002271157.1 2640483 R 444450 CDS YP_002271158.1 209397306 6971414 complement(2641574..2642317) 1 NC_011353.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2642317 cobS 6971414 cobS Escherichia coli O157:H7 str. EC4115 cobalamin synthase YP_002271158.1 2641574 R 444450 CDS YP_002271159.1 209400427 6968862 2643597..2643944 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 2643944 6968862 ECH74115_2840 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002271159.1 2643597 D 444450 CDS YP_002271160.1 209396341 6971629 2643994..2645532 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 2645532 6971629 ECH74115_2841 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002271160.1 2643994 D 444450 CDS YP_002271161.1 209397762 6967242 complement(2645773..2645937) 1 NC_011353.1 hypothetical protein 2645937 6967242 ECH74115_2842 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271161.1 2645773 R 444450 CDS YP_002271162.1 209399833 6968749 complement(2646350..2647240) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2647240 6968749 ECH74115_2843 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271162.1 2646350 R 444450 CDS YP_002271163.1 209396590 6970990 complement(2647237..2647563) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2647563 6970990 ECH74115_2844 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271163.1 2647237 R 444450 CDS YP_002271164.1 209400707 6967505 2648293..2650440 1 NC_011353.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor 2650440 6967505 ECH74115_2845 Escherichia coli O157:H7 str. EC4115 TonB-dependent receptor YP_002271164.1 2648293 D 444450 CDS YP_002271165.1 209400114 6971930 2650440..2650556 1 NC_011353.1 identified by glimmer; hypothetical protein 2650556 6971930 ECH74115_2846 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271165.1 2650440 D 444450 CDS YP_002271166.1 209399516 6971297 2650893..2651576 1 NC_011353.1 hypothetical protein 2651576 6971297 ECH74115_2847 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271166.1 2650893 D 444450 CDS YP_002271167.1 209398933 6970651 2651573..2652478 1 NC_011353.1 hypothetical protein 2652478 6970651 ECH74115_2848 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271167.1 2651573 D 444450 CDS YP_002271168.1 209396477 6970027 2652487..2653545 1 NC_011353.1 identified by match to protein family HMM PF01734; phospholipase, patatin family 2653545 6970027 ECH74115_2849 Escherichia coli O157:H7 str. EC4115 phospholipase, patatin family YP_002271168.1 2652487 D 444450 CDS YP_002271169.1 209398964 6967388 2653681..2654364 1 NC_011353.1 identified by glimmer; hypothetical protein 2654364 6967388 ECH74115_2850 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271169.1 2653681 D 444450 CDS YP_002271170.1 209395984 6970059 2654380..2654790 1 NC_011353.1 identified by glimmer; hypothetical protein 2654790 6970059 ECH74115_2852 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271170.1 2654380 D 444450 CDS YP_002271171.1 209400729 6966854 complement(2654787..2654921) 1 NC_011353.1 identified by glimmer; hypothetical protein 2654921 6966854 ECH74115_2851 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271171.1 2654787 R 444450 CDS YP_002271172.1 209399203 6971953 2655011..2655832 1 NC_011353.1 identified by match to protein family HMM PF06067; hypothetical protein 2655832 6971953 ECH74115_2853 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271172.1 2655011 D 444450 CDS YP_002271173.1 209399757 6970312 2655914..2656393 1 NC_011353.1 identified by match to protein family HMM PF03230; antirestriction protein 2656393 6970312 ECH74115_2854 Escherichia coli O157:H7 str. EC4115 antirestriction protein YP_002271173.1 2655914 D 444450 CDS YP_002271174.1 209397679 6970913 2656408..2656884 1 NC_011353.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; DNA repair protein, RadC family 2656884 6970913 ECH74115_2855 Escherichia coli O157:H7 str. EC4115 DNA repair protein, RadC family YP_002271174.1 2656408 D 444450 CDS YP_002271175.1 209398231 6968662 2656947..2657168 1 NC_011353.1 identified by match to protein family HMM PF06174; hypothetical protein 2657168 6968662 ECH74115_2856 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271175.1 2656947 D 444450 CDS YP_002271176.1 209396158 6969262 2657362..2657610 1 NC_011353.1 identified by match to protein family HMM PF06154; YagB/YeeU/YfjZ family protein 2657610 6969262 ECH74115_2857 Escherichia coli O157:H7 str. EC4115 YagB/YeeU/YfjZ family protein YP_002271176.1 2657362 D 444450 CDS YP_002271177.1 209400604 6967620 2658069..2658263 1 NC_011353.1 hypothetical protein 2658263 6967620 ECH74115_2859 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271177.1 2658069 D 444450 CDS YP_002271178.1 209396801 6968305 2658941..2659060 1 NC_011353.1 hypothetical protein 2659060 6968305 ECH74115_2861 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271178.1 2658941 D 444450 CDS YP_002271179.1 209396566 6967733 complement(2659161..2659490) 1 NC_011353.1 identified by match to protein family HMM PF04363; hypothetical protein 2659490 6967733 ECH74115_2862 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271179.1 2659161 R 444450 CDS YP_002271180.1 209400430 6967480 2659581..2659697 1 NC_011353.1 identified by glimmer; hypothetical protein 2659697 6967480 ECH74115_2864 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271180.1 2659581 D 444450 CDS YP_002271181.1 209398667 6971632 complement(2659662..2660720) 1 NC_011353.1 hypothetical protein 2660720 6971632 ECH74115_2863 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271181.1 2659662 R 444450 CDS YP_002271182.1 209395889 6969737 complement(2660919..2661392) 1 NC_011353.1 identified by match to protein family HMM PF06445; DNA gyrase inhibitor 2661392 gyrI 6969737 gyrI Escherichia coli O157:H7 str. EC4115 DNA gyrase inhibitor YP_002271182.1 2660919 R 444450 CDS YP_002271183.1 209397891 6966754 complement(2661511..2662683) 1 NC_011353.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2662683 dacD 6966754 dacD Escherichia coli O157:H7 str. EC4115 D-alanyl-D-alanine carboxypeptidase YP_002271183.1 2661511 R 444450 CDS YP_002271184.1 209399681 6968888 2662604..2662762 1 NC_011353.1 identified by glimmer; hypothetical protein 2662762 6968888 ECH74115_2867 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271184.1 2662604 D 444450 CDS YP_002271185.1 209396458 6970830 2664001..2664651 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 2664651 6970830 ECH74115_2868 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271185.1 2664001 D 444450 CDS YP_002271186.1 209400917 6967369 complement(2664875..2665750) 1 NC_011353.1 hypothetical protein 2665750 6967369 ECH74115_2869 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271186.1 2664875 R 444450 CDS YP_002271187.1 209397490 6972153 complement(2665891..2666160) 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 2666160 6972153 ECH74115_2870 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002271187.1 2665891 R 444450 CDS YP_002271188.1 209396826 6968461 complement(2666162..2667475) 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 2667475 6968461 ECH74115_2871 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002271188.1 2666162 R 444450 CDS YP_002271189.1 209396273 6967759 complement(2667540..2668139) 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 2668139 6967759 ECH74115_2872 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002271189.1 2667540 R 444450 CDS YP_002271190.1 209399897 6967166 complement(2668207..2671686) 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 2671686 6967166 ECH74115_2873 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271190.1 2668207 R 444450 CDS YP_002271191.1 209396451 6971059 complement(2671691..2671816) 1 NC_011353.1 identified by glimmer; hypothetical protein 2671816 6971059 ECH74115_2874 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271191.1 2671691 R 444450 CDS YP_002271192.1 209397250 6967361 complement(2671925..2672506) 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 2672506 6967361 ECH74115_2875 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002271192.1 2671925 R 444450 CDS YP_002271193.1 209399152 6968208 complement(2672503..2673240) 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 2673240 6968208 ECH74115_2876 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002271193.1 2672503 R 444450 CDS YP_002271194.1 209396113 6970259 complement(2673295..2674299) 1 NC_011353.1 antirepressor protein 2674299 6970259 ECH74115_2877 Escherichia coli O157:H7 str. EC4115 antirepressor protein YP_002271194.1 2673295 R 444450 CDS YP_002271195.1 209398024 6966993 complement(2674289..2674462) 1 NC_011353.1 identified by glimmer; hypothetical protein 2674462 6966993 ECH74115_2878 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271195.1 2674289 R 444450 CDS YP_002271196.1 209400258 6969037 2674672..2674890 1 NC_011353.1 transcriptional regulator 2674890 6969037 ECH74115_2879 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002271196.1 2674672 D 444450 CDS YP_002271197.1 209396890 6967391 complement(2675633..2675974) 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 2675974 6967391 ECH74115_2882 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002271197.1 2675633 R 444450 CDS YP_002271198.1 209400454 6967827 complement(2675967..2679209) 1 NC_011353.1 identified by match to protein family HMM PF06120; match to protein family HMM PF09718; match to protein family HMM TIGR01541; match to protein family HMM TIGR02675; tail length tape measure protein 2679209 6967827 ECH74115_2883 Escherichia coli O157:H7 str. EC4115 tail length tape measure protein YP_002271198.1 2675967 R 444450 CDS YP_002271199.1 209398390 6971659 complement(2679261..2679464) 1 NC_011353.1 identified by glimmer; hypothetical protein 2679464 6971659 ECH74115_2884 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271199.1 2679261 R 444450 CDS YP_002271200.1 209399274 6969434 complement(2679566..2679940) 1 NC_011353.1 identified by match to protein family HMM PF06222; phage tail assembly chaperone 2679940 6969434 ECH74115_2885 Escherichia coli O157:H7 str. EC4115 phage tail assembly chaperone YP_002271200.1 2679566 R 444450 CDS YP_002271201.1 209397216 6970390 complement(2679946..2680662) 1 NC_011353.1 identified by match to protein family HMM PF07679; major tail protein 2680662 6970390 ECH74115_2886 Escherichia coli O157:H7 str. EC4115 major tail protein YP_002271201.1 2679946 R 444450 CDS YP_002271202.1 209398245 6968174 complement(2680721..2681065) 1 NC_011353.1 identified by glimmer; hypothetical protein 2681065 6968174 ECH74115_2887 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271202.1 2680721 R 444450 CDS YP_002271203.1 209396183 6969277 complement(2681062..2681508) 1 NC_011353.1 identified by match to protein family HMM PF07772; match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 2681508 6969277 ECH74115_2888 Escherichia coli O157:H7 str. EC4115 phage protein, HK97 gp10 family YP_002271203.1 2681062 R 444450 CDS YP_002271204.1 209399805 6967069 complement(2681505..2681855) 1 NC_011353.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563; phage head-tail adaptor 2681855 6967069 ECH74115_2889 Escherichia coli O157:H7 str. EC4115 phage head-tail adaptor YP_002271204.1 2681505 R 444450 CDS YP_002271205.1 209398554 6970962 complement(2681865..2682191) 1 NC_011353.1 hypothetical protein 2682191 6970962 ECH74115_2890 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271205.1 2681865 R 444450 CDS YP_002271206.1 209399116 6969614 complement(2682271..2684772) 1 NC_011353.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 2684772 6969614 ECH74115_2891 Escherichia coli O157:H7 str. EC4115 phage portal protein, HK97 family YP_002271206.1 2682271 R 444450 CDS YP_002271207.1 209398362 6970218 complement(2684984..2686921) 1 NC_011353.1 identified by match to protein family HMM PF04586; prohead protease 2686921 6970218 ECH74115_2892 Escherichia coli O157:H7 str. EC4115 prohead protease YP_002271207.1 2684984 R 444450 CDS YP_002271208.1 209400596 6969404 complement(2686985..2688646) 1 NC_011353.1 identified by match to protein family HMM PF03354; phage terminase, large subunit 2688646 6969404 ECH74115_2893 Escherichia coli O157:H7 str. EC4115 phage terminase, large subunit YP_002271208.1 2686985 R 444450 CDS YP_002271209.1 209399903 6971807 complement(2688643..2689206) 1 NC_011353.1 terminase small subunit 2689206 6971807 ECH74115_2894 Escherichia coli O157:H7 str. EC4115 terminase small subunit YP_002271209.1 2688643 R 444450 CDS YP_002271210.1 209396770 6971067 complement(2689498..2689863) 1 NC_011353.1 identified by match to protein family HMM PF01844; HNH endonuclease 2689863 6971067 ECH74115_2895 Escherichia coli O157:H7 str. EC4115 HNH endonuclease YP_002271210.1 2689498 R 444450 CDS YP_002271211.1 209396306 6967699 2689965..2690132 1 NC_011353.1 hypothetical protein 2690132 6967699 ECH74115_2896 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271211.1 2689965 D 444450 CDS YP_002271212.1 209398221 6967201 complement(2690595..2690777) 1 NC_011353.1 bacteriophage protein 2690777 6967201 ECH74115_2897 Escherichia coli O157:H7 str. EC4115 bacteriophage protein YP_002271212.1 2690595 R 444450 CDS YP_002271213.1 209397851 6969250 complement(2690849..2691346) 1 NC_011353.1 identified by match to protein family HMM PF04383; KilA-N domain-containing protein 2691346 6969250 ECH74115_2898 Escherichia coli O157:H7 str. EC4115 KilA-N domain-containing protein YP_002271213.1 2690849 R 444450 CDS YP_002271214.1 209397031 6968843 complement(2691549..2691986) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 2691986 6968843 ECH74115_2899 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002271214.1 2691549 R 444450 CDS YP_002271215.1 209398069 6967975 complement(2691983..2692480) 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 2692480 6967975 ECH74115_2900 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002271215.1 2691983 R 444450 CDS YP_002271216.1 209396203 6969086 complement(2692480..2692695) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 2692695 6969086 ECH74115_2901 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271216.1 2692480 R 444450 CDS YP_002271217.1 209399893 6967090 complement(2692772..2693044) 1 NC_011353.1 identified by match to protein family HMM PF05696; hypothetical protein 2693044 6967090 ECH74115_2902 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271217.1 2692772 R 444450 CDS YP_002271218.1 209400140 6971055 complement(2693085..2693264) 1 NC_011353.1 identified by match to protein family HMM PF07125; hypothetical protein 2693264 6971055 ECH74115_2903 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271218.1 2693085 R 444450 CDS YP_002271219.1 209398353 6971326 complement(2693401..2695338) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 2695338 6971326 ECH74115_2904 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271219.1 2693401 R 444450 CDS YP_002271220.1 209399287 6969394 complement(2696202..2696471) 1 NC_011353.1 identified by match to protein family HMM PF02258; shigatoxin 2, subunit B 2696471 6969394 ECH74115_2905 Escherichia coli O157:H7 str. EC4115 shigatoxin 2, subunit B YP_002271220.1 2696202 R 444450 CDS YP_002271221.1 209397665 6970403 complement(2696483..2697442) 1 NC_011353.1 identified by match to protein family HMM PF00161; shiga toxin subunit A 2697442 6970403 ECH74115_2906 Escherichia coli O157:H7 str. EC4115 shiga toxin subunit A YP_002271221.1 2696483 R 444450 CDS YP_002271222.1 209398315 6972413 complement(2698092..2698580) 1 NC_011353.1 identified by match to protein family HMM PF06530; late antiterminator 2698580 6972413 ECH74115_2910 Escherichia coli O157:H7 str. EC4115 late antiterminator YP_002271222.1 2698092 R 444450 CDS YP_002271223.1 209396056 6969353 complement(2698571..2699242) 1 NC_011353.1 identified by match to protein family HMM PF00149; serine/threonine-protein phosphatase 1 2699242 6969353 ECH74115_2911 Escherichia coli O157:H7 str. EC4115 serine/threonine-protein phosphatase 1 YP_002271223.1 2698571 R 444450 CDS YP_002271224.1 209396776 6966933 complement(2699239..2699844) 1 NC_011353.1 identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein 2699844 6966933 ECH74115_2912 Escherichia coli O157:H7 str. EC4115 bacteriophage Lambda NinG protein YP_002271224.1 2699239 R 444450 CDS YP_002271225.1 209400174 6967706 complement(2699844..2700566) 1 NC_011353.1 identified by match to protein family HMM PF03374; Roi protein 2700566 6967706 ECH74115_2913 Escherichia coli O157:H7 str. EC4115 Roi protein YP_002271225.1 2699844 R 444450 CDS YP_002271226.1 209400935 6971361 complement(2700641..2701321) 1 NC_011353.1 open reading frame 2701321 6971361 ECH74115_2914 Escherichia coli O157:H7 str. EC4115 open reading frame YP_002271226.1 2700641 R 444450 CDS YP_002271227.1 209397792 6972172 complement(2701577..2702335) 1 NC_011353.1 open reading frame 2702335 6972172 ECH74115_2915 Escherichia coli O157:H7 str. EC4115 open reading frame YP_002271227.1 2701577 R 444450 CDS YP_002271228.1 209395913 6968781 complement(2702789..2703316) 1 NC_011353.1 identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712; phage N-6-adenine-methyltransferase 2703316 6968781 ECH74115_2916 Escherichia coli O157:H7 str. EC4115 phage N-6-adenine-methyltransferase YP_002271228.1 2702789 R 444450 CDS YP_002271229.1 209398742 6966780 complement(2703313..2703759) 1 NC_011353.1 identified by match to protein family HMM PF05772; protein NinB 2703759 6966780 ECH74115_2917 Escherichia coli O157:H7 str. EC4115 protein NinB YP_002271229.1 2703313 R 444450 CDS YP_002271230.1 209399482 6969818 complement(2703716..2704078) 1 NC_011353.1 identified by match to protein family HMM TIGR03655; restriction alleviation protein, Lar family 2704078 6969818 ECH74115_2918 Escherichia coli O157:H7 str. EC4115 restriction alleviation protein, Lar family YP_002271230.1 2703716 R 444450 CDS YP_002271231.1 209400775 6970616 complement(2704311..2704589) 1 NC_011353.1 hypothetical protein 2704589 6970616 ECH74115_2919 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271231.1 2704311 R 444450 CDS YP_002271232.1 209398833 6972000 complement(2704660..2706036) 1 NC_011353.1 identified by match to protein family HMM PF00772; match to protein family HMM PF03796; replicative DNA helicase 2706036 6972000 ECH74115_2920 Escherichia coli O157:H7 str. EC4115 replicative DNA helicase YP_002271232.1 2704660 R 444450 CDS YP_002271233.1 209396675 6969916 complement(2706033..2706854) 1 NC_011353.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; replication of DNA 2706854 6969916 ECH74115_2921 Escherichia coli O157:H7 str. EC4115 replication of DNA YP_002271233.1 2706033 R 444450 CDS YP_002271234.1 209399887 6967596 complement(2706841..2707002) 1 NC_011353.1 hypothetical protein 2707002 6967596 ECH74115_2922 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271234.1 2706841 R 444450 CDS YP_002271235.1 209399793 6971049 complement(2707035..2707331) 1 NC_011353.1 identified by match to protein family HMM PF05269; bacteriophage CII protein 2707331 6971049 ECH74115_2923 Escherichia coli O157:H7 str. EC4115 bacteriophage CII protein YP_002271235.1 2707035 R 444450 CDS YP_002271236.1 209400501 6970950 2707764..2708459 1 NC_011353.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381; repressor protein 2708459 6970950 ECH74115_2924 Escherichia coli O157:H7 str. EC4115 repressor protein YP_002271236.1 2707764 D 444450 CDS YP_002271237.1 209396847 6971706 2708604..2708738 1 NC_011353.1 identified by glimmer; hypothetical protein 2708738 6971706 ECH74115_2925 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271237.1 2708604 D 444450 CDS YP_002271238.1 209397757 6967780 2709102..2709482 1 NC_011353.1 hypothetical protein 2709482 6967780 ECH74115_2926 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271238.1 2709102 D 444450 CDS YP_002271239.1 209398020 6968744 2710542..2710793 1 NC_011353.1 identified by glimmer; hypothetical protein 2710793 6968744 ECH74115_2927 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271239.1 2710542 D 444450 CDS YP_002271240.1 209397584 6969033 2710976..2711344 1 NC_011353.1 identified by glimmer; hypothetical protein 2711344 6969033 ECH74115_2928 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271240.1 2710976 D 444450 CDS YP_002271241.1 209398612 6968562 2711550..2711693 1 NC_011353.1 identified by match to protein family HMM PF06301; kil 2711693 6968562 ECH74115_2929 Escherichia coli O157:H7 str. EC4115 kil YP_002271241.1 2711550 D 444450 CDS YP_002271242.1 209400682 6969675 2711768..2712064 1 NC_011353.1 identified by match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 2712064 gam 6969675 gam Escherichia coli O157:H7 str. EC4115 host-nuclease inhibitor protein Gam YP_002271242.1 2711768 D 444450 CDS YP_002271243.1 209399783 6971902 2712070..2712855 1 NC_011353.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 2712855 bet 6971902 bet Escherichia coli O157:H7 str. EC4115 phage recombination protein Bet YP_002271243.1 2712070 D 444450 CDS YP_002271244.1 209396390 6970940 complement(2713150..2714040) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2714040 6970940 ECH74115_2932 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271244.1 2713150 R 444450 CDS YP_002271245.1 209397801 6967296 complement(2714037..2714363) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2714363 6967296 ECH74115_2933 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271245.1 2714037 R 444450 CDS YP_002271246.1 209398862 6968790 2714456..2714845 1 NC_011353.1 exonuclease 2714845 6968790 ECH74115_2934 Escherichia coli O157:H7 str. EC4115 exonuclease YP_002271246.1 2714456 D 444450 CDS YP_002271247.1 209397311 6969948 2715075..2715188 1 NC_011353.1 hypothetical protein 2715188 6969948 ECH74115_2935 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271247.1 2715075 D 444450 CDS YP_002271248.1 209396401 6968273 2715265..2715480 1 NC_011353.1 hypothetical protein 2715480 6968273 ECH74115_2936 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271248.1 2715265 D 444450 CDS YP_002271249.1 209398885 6967308 2715797..2716744 1 NC_011353.1 identified by match to protein family HMM PF04447; hypothetical protein 2716744 6967308 ECH74115_2937 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271249.1 2715797 D 444450 CDS YP_002271250.1 209398915 6970488 2717609..2717959 1 NC_011353.1 hypothetical protein 2717959 6970488 ECH74115_2940 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271250.1 2717609 D 444450 CDS YP_002271251.1 209395875 6970007 2718147..2718491 1 NC_011353.1 lipoprotein 2718491 6970007 ECH74115_2941 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002271251.1 2718147 D 444450 CDS YP_002271252.1 209397443 6966739 2718569..2718760 1 NC_011353.1 identified by match to protein family HMM PF05930; transcriptional regulator, AlpA family 2718760 6966739 ECH74115_2943 Escherichia coli O157:H7 str. EC4115 transcriptional regulator, AlpA family YP_002271252.1 2718569 D 444450 CDS YP_002271253.1 209400128 6968413 complement(2718741..2719919) 1 NC_011353.1 identified by match to protein family HMM PF00589; phage integrase family protein 2719919 6968413 ECH74115_2942 Escherichia coli O157:H7 str. EC4115 phage integrase family protein YP_002271253.1 2718741 R 444450 CDS YP_002271254.1 209398513 6971313 2720101..2721525 1 NC_011353.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2721525 sbcB 6971313 sbcB Escherichia coli O157:H7 str. EC4115 exonuclease I YP_002271254.1 2720101 D 444450 CDS YP_002271255.1 209400522 6969571 complement(2721568..2721795) 1 NC_011353.1 identified by match to protein family HMM PF01206; hypothetical protein 2721795 6969571 ECH74115_2945 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271255.1 2721568 R 444450 CDS YP_002271256.1 209395827 6971729 complement(2721809..2722867) 1 NC_011353.1 identified by match to protein family HMM PF04143; membrane protein, YeeE/YedE family 2722867 6971729 ECH74115_2946 Escherichia coli O157:H7 str. EC4115 membrane protein, YeeE/YedE family YP_002271256.1 2721809 R 444450 CDS YP_002271257.1 209399297 6966684 complement(2723046..2724404) 1 NC_011353.1 identified by match to protein family HMM PF00324; amino acid permease 2724404 yeeF 6966684 yeeF Escherichia coli O157:H7 str. EC4115 amino acid permease YP_002271257.1 2723046 R 444450 CDS YP_002271258.1 209398416 6970872 complement(2724671..2725600) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2725600 6970872 ECH74115_2949 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002271258.1 2724671 R 444450 CDS YP_002271259.1 209398834 6969463 complement(2725646..2726470) 1 NC_011353.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase family protein 2726470 6969463 ECH74115_2950 Escherichia coli O157:H7 str. EC4115 NAD dependent epimerase/dehydratase family protein YP_002271259.1 2725646 R 444450 CDS YP_002271260.1 209396922 6969917 2727092..2727991 1 NC_011353.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2727991 hisG 6969917 hisG Escherichia coli O157:H7 str. EC4115 ATP phosphoribosyltransferase YP_002271260.1 2727092 D 444450 CDS YP_002271261.1 209397361 6967860 2727997..2729301 1 NC_011353.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2729301 hisD 6967860 hisD Escherichia coli O157:H7 str. EC4115 histidinol dehydrogenase YP_002271261.1 2727997 D 444450 CDS YP_002271262.1 209396323 6968328 2729298..2730368 1 NC_011353.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2730368 hisC 6968328 hisC Escherichia coli O157:H7 str. EC4115 histidinol-phosphate aminotransferase YP_002271262.1 2729298 D 444450 CDS YP_002271263.1 209400725 6967220 2730368..2731435 1 NC_011353.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2731435 hisB 6967220 hisB Escherichia coli O157:H7 str. EC4115 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002271263.1 2730368 D 444450 CDS YP_002271264.1 209396111 6971949 2731435..2732025 1 NC_011353.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2732025 hisH 6971949 hisH Escherichia coli O157:H7 str. EC4115 imidazole glycerol phosphate synthase subunit HisH YP_002271264.1 2731435 D 444450 CDS YP_002271265.1 209400912 6966991 2732025..2732762 1 NC_011353.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2732762 hisA 6966991 hisA Escherichia coli O157:H7 str. EC4115 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002271265.1 2732025 D 444450 CDS YP_002271266.1 209397885 6972148 2732744..2733520 1 NC_011353.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2733520 hisF 6972148 hisF Escherichia coli O157:H7 str. EC4115 imidazole glycerol phosphate synthase subunit HisF YP_002271266.1 2732744 D 444450 CDS YP_002271267.1 209397099 6968882 2733514..2734125 1 NC_011353.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2734125 hisIE 6968882 hisIE Escherichia coli O157:H7 str. EC4115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_002271267.1 2733514 D 444450 CDS YP_002271268.1 209399038 6968047 complement(2734222..2735199) 1 NC_011353.1 identified by match to protein family HMM PF02706; chain length determinant protein 2735199 6968047 ECH74115_2960 Escherichia coli O157:H7 str. EC4115 chain length determinant protein YP_002271268.1 2734222 R 444450 CDS YP_002271269.1 209398959 6970139 complement(2735345..2736511) 1 NC_011353.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 2736511 ugd 6970139 ugd Escherichia coli O157:H7 str. EC4115 UDP-glucose 6-dehydrogenase YP_002271269.1 2735345 R 444450 CDS YP_002271270.1 209400871 6970053 complement(2736760..2738166) 1 NC_011353.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2738166 gnd 6970053 gnd Escherichia coli O157:H7 str. EC4115 6-phosphogluconate dehydrogenase YP_002271270.1 2736760 R 444450 CDS YP_002271271.1 209400062 6972103 2739924..2740037 1 NC_011353.1 identified by glimmer; hypothetical protein 2740037 6972103 ECH74115_2963 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271271.1 2739924 D 444450 CDS YP_002271272.1 209397519 6971241 complement(2740295..2741665) 1 NC_011353.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 2741665 6971241 ECH74115_2964 Escherichia coli O157:H7 str. EC4115 phosphomannomutase YP_002271272.1 2740295 R 444450 CDS YP_002271273.1 209398268 6968492 complement(2741669..2743117) 1 NC_011353.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2743117 6968492 ECH74115_2965 Escherichia coli O157:H7 str. EC4115 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002271273.1 2741669 R 444450 CDS YP_002271274.1 209397532 6969300 complement(2743099..2743608) 1 NC_011353.1 identified by match to protein family HMM PF00293; GDP-mannose mannosyl hydrolase 2743608 6969300 ECH74115_2966 Escherichia coli O157:H7 str. EC4115 GDP-mannose mannosyl hydrolase YP_002271274.1 2743099 R 444450 CDS YP_002271275.1 209397079 6968505 complement(2743611..2744576) 1 NC_011353.1 identified by match to protein family HMM PF01370; GDP-L-fucose synthetase 2744576 6968505 ECH74115_2967 Escherichia coli O157:H7 str. EC4115 GDP-L-fucose synthetase YP_002271275.1 2743611 R 444450 CDS YP_002271276.1 209400350 6968025 complement(2744579..2745697) 1 NC_011353.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase 2745697 gmd 6968025 gmd Escherichia coli O157:H7 str. EC4115 GDP-mannose 4,6-dehydratase YP_002271276.1 2744579 R 444450 CDS YP_002271277.1 209398526 6971548 complement(2745717..2746931) 1 NC_011353.1 identified by match to protein family HMM PF00534; WbdP 2746931 6971548 ECH74115_2969 Escherichia coli O157:H7 str. EC4115 WbdP YP_002271277.1 2745717 R 444450 CDS YP_002271278.1 209396053 6969585 complement(2746956..2748050) 1 NC_011353.1 identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS family aminotransferase 2748050 6969585 ECH74115_2970 Escherichia coli O157:H7 str. EC4115 DegT/DnrJ/EryC1/StrS family aminotransferase YP_002271278.1 2746956 R 444450 CDS YP_002271279.1 209400642 6966930 complement(2748053..2749438) 1 NC_011353.1 identified by match to protein family HMM PF01943; O antigen flippase 2749438 6966930 ECH74115_2971 Escherichia coli O157:H7 str. EC4115 O antigen flippase YP_002271279.1 2748053 R 444450 CDS YP_002271280.1 209397211 6971856 complement(2749431..2750177) 1 NC_011353.1 WbdO 2750177 6971856 ECH74115_2972 Escherichia coli O157:H7 str. EC4115 WbdO YP_002271280.1 2749431 R 444450 CDS YP_002271281.1 209396471 6968169 complement(2750146..2751330) 1 NC_011353.1 O antigen polymerase 2751330 6968169 ECH74115_2973 Escherichia coli O157:H7 str. EC4115 O antigen polymerase YP_002271281.1 2750146 R 444450 CDS YP_002271282.1 209400561 6967382 complement(2751327..2752109) 1 NC_011353.1 identified by match to protein family HMM PF00535; WbdN 2752109 6967382 ECH74115_2974 Escherichia coli O157:H7 str. EC4115 WbdN YP_002271282.1 2751327 R 444450 CDS YP_002271283.1 209400008 6971770 complement(2752428..2753321) 1 NC_011353.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 2753321 galF 6971770 galF Escherichia coli O157:H7 str. EC4115 UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_002271283.1 2752428 R 444450 CDS YP_002271284.1 209398311 6971182 complement(2753564..2754559) 1 NC_011353.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; UDP-N-acetylglucosamine 4-epimerase 2754559 gne 6971182 gne Escherichia coli O157:H7 str. EC4115 UDP-N-acetylglucosamine 4-epimerase YP_002271284.1 2753564 R 444450 CDS YP_002271285.1 209397395 6969348 complement(2754717..2756111) 1 NC_011353.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2756111 wcaM 6969348 wcaM Escherichia coli O157:H7 str. EC4115 colanic acid biosynthesis protein YP_002271285.1 2754717 R 444450 CDS YP_002271286.1 209399030 6968361 complement(2756122..2757342) 1 NC_011353.1 identified by match to protein family HMM PF00534; colanic acid biosynthesis glycosyl transferase WcaL 2757342 wcaL 6968361 wcaL Escherichia coli O157:H7 str. EC4115 colanic acid biosynthesis glycosyl transferase WcaL YP_002271286.1 2756122 R 444450 CDS YP_002271287.1 209398906 6970131 complement(2757339..2758619) 1 NC_011353.1 identified by match to protein family HMM PF04230; pyruvyl transferase 2758619 wcaK 6970131 wcaK Escherichia coli O157:H7 str. EC4115 pyruvyl transferase YP_002271287.1 2757339 R 444450 CDS YP_002271288.1 209398668 6969998 complement(2758799..2760277) 1 NC_011353.1 identified by match to protein family HMM PF01943; colanic acid exporter 2760277 wzxC 6969998 wzxC Escherichia coli O157:H7 str. EC4115 colanic acid exporter YP_002271288.1 2758799 R 444450 CDS YP_002271289.1 209400434 6969738 complement(2760279..2761673) 1 NC_011353.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2761673 6969738 ECH74115_2981 Escherichia coli O157:H7 str. EC4115 UDP-glucose lipid carrier transferase YP_002271289.1 2760279 R 444450 CDS YP_002271290.1 209396705 6971636 complement(2761728..2763098) 1 NC_011353.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 2763098 cpsG 6971636 cpsG Escherichia coli O157:H7 str. EC4115 phosphomannomutase YP_002271290.1 2761728 R 444450 CDS YP_002271291.1 209396121 6967629 2763124..2763282 1 NC_011353.1 hypothetical protein 2763282 6967629 ECH74115_2983 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271291.1 2763124 D 444450 CDS YP_002271292.1 209396318 6967001 complement(2763291..2764727) 1 NC_011353.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase 2764727 cpsB 6967001 cpsB Escherichia coli O157:H7 str. EC4115 mannose-1-phosphate guanylyltransferase YP_002271292.1 2763291 R 444450 CDS YP_002271293.1 209396871 6967214 complement(2764730..2765953) 1 NC_011353.1 identified by match to protein family HMM PF00534; glycosyl transferase family protein 2765953 wcaI 6967214 wcaI Escherichia coli O157:H7 str. EC4115 glycosyl transferase family protein YP_002271293.1 2764730 R 444450 CDS YP_002271294.1 209399010 6967806 complement(2765950..2766429) 1 NC_011353.1 identified by match to protein family HMM PF00293; GDP-mannose mannosyl hydrolase 2766429 nudD 6967806 nudD Escherichia coli O157:H7 str. EC4115 GDP-mannose mannosyl hydrolase YP_002271294.1 2765950 R 444450 CDS YP_002271295.1 209399612 6970109 complement(2766432..2767397) 1 NC_011353.1 identified by match to protein family HMM PF01370; GDP-L-fucose synthetase 2767397 fcl 6970109 fcl Escherichia coli O157:H7 str. EC4115 GDP-L-fucose synthetase YP_002271295.1 2766432 R 444450 CDS YP_002271296.1 209400542 6970756 complement(2767400..2768521) 1 NC_011353.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase 2768521 gmd 6970756 gmd Escherichia coli O157:H7 str. EC4115 GDP-mannose 4,6-dehydratase YP_002271296.1 2767400 R 444450 CDS YP_002271297.1 209400766 6971750 complement(2768550..2769098) 1 NC_011353.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2769098 6971750 ECH74115_2989 Escherichia coli O157:H7 str. EC4115 colanic acid biosynthesis acetyltransferase WcaF YP_002271297.1 2768550 R 444450 CDS YP_002271298.1 209396416 6971991 complement(2769114..2769860) 1 NC_011353.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 2769860 wcaE 6971991 wcaE Escherichia coli O157:H7 str. EC4115 glycosyl transferase family protein YP_002271298.1 2769114 R 444450 CDS YP_002271299.1 209399912 6967323 complement(2769871..2771088) 1 NC_011353.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2771088 wcaD 6967323 wcaD Escherichia coli O157:H7 str. EC4115 colanic acid biosynthesis protein YP_002271299.1 2769871 R 444450 CDS YP_002271300.1 209398209 6971076 complement(2771063..2772280) 1 NC_011353.1 glycosyl transferase family protein 2772280 wcaC 6971076 wcaC Escherichia coli O157:H7 str. EC4115 glycosyl transferase family protein YP_002271300.1 2771063 R 444450 CDS YP_002271301.1 209395739 6969238 complement(2772277..2772765) 1 NC_011353.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2772765 6969238 ECH74115_2993 Escherichia coli O157:H7 str. EC4115 colanic acid biosynthesis acetyltransferase WcaB YP_002271301.1 2772277 R 444450 CDS YP_002271302.1 209395746 6966594 complement(2772768..2773607) 1 NC_011353.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 2773607 wcaA 6966594 wcaA Escherichia coli O157:H7 str. EC4115 glycosyl transferase family protein YP_002271302.1 2772768 R 444450 CDS YP_002271303.1 209396474 6966601 complement(2773700..2775862) 1 NC_011353.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2775862 wzc 6966601 wzc Escherichia coli O157:H7 str. EC4115 tyrosine kinase YP_002271303.1 2773700 R 444450 CDS YP_002271304.1 209400491 6967385 complement(2775865..2776308) 1 NC_011353.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2776308 wzb 6967385 wzb Escherichia coli O157:H7 str. EC4115 tyrosine phosphatase YP_002271304.1 2775865 R 444450 CDS YP_002271305.1 209398882 6971696 complement(2776314..2777453) 1 NC_011353.1 identified by match to protein family HMM PF02563; polysaccharide biosynthesis/export protein 2777453 6971696 ECH74115_2997 Escherichia coli O157:H7 str. EC4115 polysaccharide biosynthesis/export protein YP_002271305.1 2776314 R 444450 CDS YP_002271306.1 209399597 6969971 2778112..2779695 1 NC_011353.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein 2779695 6969971 ECH74115_2998 Escherichia coli O157:H7 str. EC4115 TerC family/CBS/transporter associated domain-containing protein YP_002271306.1 2778112 D 444450 CDS YP_002271307.1 209397344 6970738 2779770..2780108 1 NC_011353.1 identified by match to protein family HMM PF05973; hypothetical protein 2780108 6970738 ECH74115_2999 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271307.1 2779770 D 444450 CDS YP_002271308.1 209396178 6968311 2780098..2780388 1 NC_011353.1 identified by match to protein family HMM PF01381; DNA-binding protein 2780388 6968311 ECH74115_3000 Escherichia coli O157:H7 str. EC4115 DNA-binding protein YP_002271308.1 2780098 D 444450 CDS YP_002271309.1 209395947 6967064 complement(2780441..2782294) 1 NC_011353.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2782294 asmA 6967064 asmA Escherichia coli O157:H7 str. EC4115 assembly protein YP_002271309.1 2780441 R 444450 CDS YP_002271310.1 209396549 6966814 complement(2782316..2782897) 1 NC_011353.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2782897 dcd 6966814 dcd Escherichia coli O157:H7 str. EC4115 deoxycytidine triphosphate deaminase YP_002271310.1 2782316 R 444450 CDS YP_002271311.1 209399953 6967463 complement(2782989..2783630) 1 NC_011353.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2783630 udk 6967463 udk Escherichia coli O157:H7 str. EC4115 uridine kinase YP_002271311.1 2782989 R 444450 CDS YP_002271312.1 209400907 6971168 complement(2787367..2788215) 1 NC_011353.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2788215 alkA 6971168 alkA Escherichia coli O157:H7 str. EC4115 3-methyladenine DNA glycosylase YP_002271312.1 2787367 R 444450 CDS YP_002271313.1 209397796 6972142 2788349..2789701 1 NC_011353.1 chaperone 2789701 6972142 ECH74115_3007 Escherichia coli O157:H7 str. EC4115 chaperone YP_002271313.1 2788349 D 444450 CDS YP_002271314.1 209397213 6968785 complement(2789714..2791654) 1 NC_011353.1 hypothetical protein 2791654 6968785 ECH74115_3008 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271314.1 2789714 R 444450 CDS YP_002271315.1 209396275 6968171 complement(2791651..2792412) 1 NC_011353.1 hypothetical protein 2792412 6968171 ECH74115_3009 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271315.1 2791651 R 444450 CDS YP_002271316.1 209395812 6967168 complement(2792409..2793068) 1 NC_011353.1 identified by match to protein family HMM PF00092; von Willebrand factor type A domain-containing protein 2793068 6967168 ECH74115_3010 Escherichia coli O157:H7 str. EC4115 von Willebrand factor type A domain-containing protein YP_002271316.1 2792409 R 444450 CDS YP_002271317.1 209400133 6972317 2794284..2795531 1 NC_011353.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2795531 mdtA 6972317 mdtA Escherichia coli O157:H7 str. EC4115 multidrug efflux system subunit MdtA YP_002271317.1 2794284 D 444450 CDS YP_002271318.1 209399550 6971319 2795531..2798653 1 NC_011353.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2798653 mdtB 6971319 mdtB Escherichia coli O157:H7 str. EC4115 multidrug efflux system subunit MdtB YP_002271318.1 2795531 D 444450 CDS YP_002271319.1 209398631 6970687 2798654..2801731 1 NC_011353.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2801731 mdtC 6970687 mdtC Escherichia coli O157:H7 str. EC4115 multidrug efflux system subunit MdtC YP_002271319.1 2798654 D 444450 CDS YP_002271320.1 209399899 6969696 2801732..2803147 1 NC_011353.1 identified by match to protein family HMM PF07690; multidrug efflux system protein MdtE 2803147 6969696 ECH74115_3017 Escherichia coli O157:H7 str. EC4115 multidrug efflux system protein MdtE YP_002271320.1 2801732 D 444450 CDS YP_002271321.1 209397988 6971062 2803144..2804547 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; signal transduction histidine-protein kinase BaeS 2804547 baeS 6971062 baeS Escherichia coli O157:H7 str. EC4115 signal transduction histidine-protein kinase BaeS YP_002271321.1 2803144 D 444450 CDS YP_002271322.1 209398758 6968999 2804544..2805266 1 NC_011353.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2805266 baeR 6968999 baeR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator BaeR YP_002271322.1 2804544 D 444450 CDS YP_002271323.1 209401008 6969835 2805457..2805789 1 NC_011353.1 identified by match to protein family HMM PF07411; hypothetical protein 2805789 6969835 ECH74115_3020 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271323.1 2805457 D 444450 CDS YP_002271324.1 209396381 6972250 2805937..2807298 1 NC_011353.1 identified by match to protein family HMM PF01136; U32 family peptidase 2807298 6972250 ECH74115_3021 Escherichia coli O157:H7 str. EC4115 U32 family peptidase YP_002271324.1 2805937 D 444450 CDS YP_002271325.1 209399478 6972290 complement(2807572..2807826) 1 NC_011353.1 in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 2807826 6972290 ECH74115_3023 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002271325.1 2807572 R 444450 CDS YP_002271326.1 209398874 6970611 complement(2807872..2809035) 1 NC_011353.1 identified by match to protein family HMM PF05954; phage late control gene D protein 2809035 6970611 ECH74115_3024 Escherichia coli O157:H7 str. EC4115 phage late control gene D protein YP_002271326.1 2807872 R 444450 CDS YP_002271327.1 209397920 6969960 complement(2809035..2809514) 1 NC_011353.1 identified by match to protein family HMM PF06995; phage protein gpU 2809514 gpU 6969960 gpU Escherichia coli O157:H7 str. EC4115 phage protein gpU YP_002271327.1 2809035 R 444450 CDS YP_002271328.1 209397347 6968919 complement(2809529..2811976) 1 NC_011353.1 identified by match to protein family HMM TIGR01760; phage tail tape measure protein, TP901 family 2811976 6968919 ECH74115_3026 Escherichia coli O157:H7 str. EC4115 phage tail tape measure protein, TP901 family YP_002271328.1 2809529 R 444450 CDS YP_002271329.1 209396398 6969575 complement(2812453..2812971) 1 NC_011353.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611; phage major tail tube protein FII 2812971 6969575 ECH74115_3029 Escherichia coli O157:H7 str. EC4115 phage major tail tube protein FII YP_002271329.1 2812453 R 444450 CDS YP_002271330.1 209397008 6967305 complement(2812984..2814174) 1 NC_011353.1 identified by match to protein family HMM PF04984; phage tail sheath protein 2814174 6967305 ECH74115_3030 Escherichia coli O157:H7 str. EC4115 phage tail sheath protein YP_002271330.1 2812984 R 444450 CDS YP_002271331.1 209399537 6967950 complement(2814234..2814827) 1 NC_011353.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796; DNA-invertase 2814827 6967950 ECH74115_3031 Escherichia coli O157:H7 str. EC4115 DNA-invertase YP_002271331.1 2814234 R 444450 CDS YP_002271332.1 209400071 6970673 2814858..2815388 1 NC_011353.1 identified by match to protein family HMM PF07484; tail collar domain-containing protein 2815388 6970673 ECH74115_3032 Escherichia coli O157:H7 str. EC4115 tail collar domain-containing protein YP_002271332.1 2814858 D 444450 CDS YP_002271333.1 209397910 6971250 2815388..2815990 1 NC_011353.1 identified by match to protein family HMM PF02413; tail fiber assembly protein-like protein 2815990 6971250 ECH74115_3034 Escherichia coli O157:H7 str. EC4115 tail fiber assembly protein-like protein YP_002271333.1 2815388 D 444450 CDS YP_002271334.1 209398160 6968909 complement(2815962..2816405) 1 NC_011353.1 identified by match to protein family HMM PF02413; tail fiber assembly protein 2816405 6968909 ECH74115_3033 Escherichia coli O157:H7 str. EC4115 tail fiber assembly protein YP_002271334.1 2815962 R 444450 CDS YP_002271335.1 209395954 6969184 complement(2816426..2817625) 1 NC_011353.1 phage tail collar domain-containing protein 2817625 6969184 ECH74115_3035 Escherichia coli O157:H7 str. EC4115 phage tail collar domain-containing protein YP_002271335.1 2816426 R 444450 CDS YP_002271336.1 209396493 6966821 complement(2817622..2818233) 1 NC_011353.1 identified by match to protein family HMM PF09684; match to protein family HMM TIGR01634; tail protein I 2818233 6966821 ECH74115_3036 Escherichia coli O157:H7 str. EC4115 tail protein I YP_002271336.1 2817622 R 444450 CDS YP_002271337.1 209400245 6967405 complement(2818226..2819134) 1 NC_011353.1 identified by match to protein family HMM PF04865; baseplate assembly protein GpJ 2819134 6967405 ECH74115_3037 Escherichia coli O157:H7 str. EC4115 baseplate assembly protein GpJ YP_002271337.1 2818226 R 444450 CDS YP_002271338.1 209396536 6971436 complement(2819139..2819486) 1 NC_011353.1 identified by match to protein family HMM PF04965; baseplate assembly protein GpW 2819486 6971436 ECH74115_3038 Escherichia coli O157:H7 str. EC4115 baseplate assembly protein GpW YP_002271338.1 2819139 R 444450 CDS YP_002271339.1 209399626 6967449 complement(2819483..2820118) 1 NC_011353.1 identified by match to protein family HMM PF04717; match to protein family HMM TIGR01644; phage baseplate assembly protein GpV 2820118 6967449 ECH74115_3039 Escherichia coli O157:H7 str. EC4115 phage baseplate assembly protein GpV YP_002271339.1 2819483 R 444450 CDS YP_002271340.1 209400151 6970770 complement(2820185..2820637) 1 NC_011353.1 identified by match to protein family HMM PF05069; match to protein family HMM TIGR01635; phage virion morphogenesis protein GpS 2820637 6970770 ECH74115_3040 Escherichia coli O157:H7 str. EC4115 phage virion morphogenesis protein GpS YP_002271340.1 2820185 R 444450 CDS YP_002271341.1 209397072 6971337 complement(2820630..2821097) 1 NC_011353.1 identified by match to protein family HMM PF06891; phage tail completion protein GpR 2821097 6971337 ECH74115_3041 Escherichia coli O157:H7 str. EC4115 phage tail completion protein GpR YP_002271341.1 2820630 R 444450 CDS YP_002271342.1 209397855 6968018 complement(2821060..2821218) 1 NC_011353.1 phage lysis protein 2821218 6968018 ECH74115_3042 Escherichia coli O157:H7 str. EC4115 phage lysis protein YP_002271342.1 2821060 R 444450 CDS YP_002271343.1 209395892 6968847 complement(2821205..2821630) 1 NC_011353.1 identified by match to protein family HMM TIGR03495; phage lysis timing protein LysB 2821630 6968847 ECH74115_3043 Escherichia coli O157:H7 str. EC4115 phage lysis timing protein LysB YP_002271343.1 2821205 R 444450 CDS YP_002271344.1 209396666 6966758 complement(2821618..2822043) 1 NC_011353.1 phage lysis protein LysA 2822043 6966758 ECH74115_3044 Escherichia coli O157:H7 str. EC4115 phage lysis protein LysA YP_002271344.1 2821618 R 444450 CDS YP_002271345.1 209400105 6967587 complement(2822058..2822555) 1 NC_011353.1 identified by match to protein family HMM PF00959; phage lysozyme 2822555 6967587 ECH74115_3045 Escherichia coli O157:H7 str. EC4115 phage lysozyme YP_002271345.1 2822058 R 444450 CDS YP_002271346.1 209395940 6971287 complement(2822555..2822836) 1 NC_011353.1 identified by match to protein family HMM PF04550; phage holin GpY 2822836 6971287 ECH74115_3046 Escherichia coli O157:H7 str. EC4115 phage holin GpY YP_002271346.1 2822555 R 444450 CDS YP_002271347.1 209398940 6966807 complement(2822840..2823043) 1 NC_011353.1 identified by match to protein family HMM PF05489; phage tail protein GpX 2823043 6966807 ECH74115_3047 Escherichia coli O157:H7 str. EC4115 phage tail protein GpX YP_002271347.1 2822840 R 444450 CDS YP_002271348.1 209398475 6970034 complement(2823043..2823516) 1 NC_011353.1 identified by match to protein family HMM PF05926; phage head completion protein GPL 2823516 6970034 ECH74115_3048 Escherichia coli O157:H7 str. EC4115 phage head completion protein GPL YP_002271348.1 2823043 R 444450 CDS YP_002271349.1 209400740 6969531 complement(2823652..2824395) 1 NC_011353.1 identified by match to protein family HMM PF05944; phage small terminase subunit GpM 2824395 6969531 ECH74115_3049 Escherichia coli O157:H7 str. EC4115 phage small terminase subunit GpM YP_002271349.1 2823652 R 444450 CDS YP_002271350.1 209400016 6971965 complement(2824399..2825472) 1 NC_011353.1 identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551; phage major capsid protein GpN 2825472 6971965 ECH74115_3050 Escherichia coli O157:H7 str. EC4115 phage major capsid protein GpN YP_002271350.1 2824399 R 444450 CDS YP_002271351.1 209400856 6971191 complement(2825531..2826385) 1 NC_011353.1 identified by match to protein family HMM PF05929; phage capsid scaffolding protein GpO 2826385 6971191 ECH74115_3051 Escherichia coli O157:H7 str. EC4115 phage capsid scaffolding protein GpO YP_002271351.1 2825531 R 444450 CDS YP_002271352.1 209400321 6972087 2826559..2828331 1 NC_011353.1 identified by match to protein family HMM PF03237; match to protein family HMM PF06056; phage large terminase subunit GpP 2828331 6972087 ECH74115_3052 Escherichia coli O157:H7 str. EC4115 phage large terminase subunit GpP YP_002271352.1 2826559 D 444450 CDS YP_002271353.1 209397035 6971517 2828331..2829365 1 NC_011353.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540; phage portal protein, pbsx family 2829365 6971517 ECH74115_3053 Escherichia coli O157:H7 str. EC4115 phage portal protein, pbsx family YP_002271353.1 2828331 D 444450 CDS YP_002271354.1 209396442 6967979 complement(2829404..2829565) 1 NC_011353.1 identified by glimmer; hypothetical protein 2829565 6967979 ECH74115_3054 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271354.1 2829404 R 444450 CDS YP_002271355.1 209398794 6967352 complement(2829683..2831650) 1 NC_011353.1 hypothetical protein 2831650 6967352 ECH74115_3055 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271355.1 2829683 R 444450 CDS YP_002271356.1 209397914 6969873 complement(2831650..2832102) 1 NC_011353.1 identified by glimmer; hypothetical protein 2832102 6969873 ECH74115_3056 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271356.1 2831650 R 444450 CDS YP_002271357.1 209400285 6968913 complement(2832149..2833372) 1 NC_011353.1 identified by match to protein family HMM PF05057; match to protein family HMM PF07819; hypothetical protein 2833372 6968913 ECH74115_3057 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271357.1 2832149 R 444450 CDS YP_002271358.1 209398781 6971479 complement(2833462..2835744) 1 NC_011353.1 identified by match to protein family HMM PF05840; bacteriophage replication gene A protein 2835744 6971479 ECH74115_3058 Escherichia coli O157:H7 str. EC4115 bacteriophage replication gene A protein YP_002271358.1 2833462 R 444450 CDS YP_002271359.1 209400847 6969859 complement(2835734..2836009) 1 NC_011353.1 hypothetical protein 2836009 6969859 ECH74115_3059 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271359.1 2835734 R 444450 CDS YP_002271360.1 209400322 6972078 complement(2836006..2836230) 1 NC_011353.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; C4-type zinc finger protein, DksA/TraR family 2836230 6972078 ECH74115_3060 Escherichia coli O157:H7 str. EC4115 C4-type zinc finger protein, DksA/TraR family YP_002271360.1 2836006 R 444450 CDS YP_002271361.1 209397528 6971518 complement(2836233..2836532) 1 NC_011353.1 hypothetical protein 2836532 6971518 ECH74115_3061 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271361.1 2836233 R 444450 CDS YP_002271362.1 209398104 6968501 complement(2836532..2836756) 1 NC_011353.1 hypothetical protein 2836756 6968501 ECH74115_3062 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271362.1 2836532 R 444450 CDS YP_002271363.1 209399363 6969123 complement(2836820..2837320) 1 NC_011353.1 replication gene B protein 2837320 6969123 ECH74115_3063 Escherichia coli O157:H7 str. EC4115 replication gene B protein YP_002271363.1 2836820 R 444450 CDS YP_002271364.1 209398785 6970486 complement(2837317..2837487) 1 NC_011353.1 hypothetical protein 2837487 6970486 ECH74115_3064 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271364.1 2837317 R 444450 CDS YP_002271365.1 209398812 6969863 complement(2837498..2837683) 1 NC_011353.1 Cox protein 2837683 6969863 ECH74115_3065 Escherichia coli O157:H7 str. EC4115 Cox protein YP_002271365.1 2837498 R 444450 CDS YP_002271366.1 209400896 6969892 2838310..2839323 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase 2839323 6969892 ECH74115_3066 Escherichia coli O157:H7 str. EC4115 integrase YP_002271366.1 2838310 D 444450 CDS YP_002271367.1 209396353 6972130 complement(2839588..2839920) 1 NC_011353.1 hypothetical protein 2839920 6972130 ECH74115_3067 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271367.1 2839588 R 444450 CDS YP_002271368.1 209396727 6967255 2840311..2841210 1 NC_011353.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2841210 6967255 ECH74115_3068 Escherichia coli O157:H7 str. EC4115 lipid kinase YP_002271368.1 2840311 D 444450 CDS YP_002271369.1 209396656 6967653 complement(2841292..2842071) 1 NC_011353.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; galactitol utilization operon repressor 2842071 gatR 6967653 gatR Escherichia coli O157:H7 str. EC4115 galactitol utilization operon repressor YP_002271369.1 2841292 R 444450 CDS YP_002271370.1 209395932 6967577 complement(2842171..2843211) 1 NC_011353.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2843211 gatD 6967577 gatD Escherichia coli O157:H7 str. EC4115 galactitol-1-phosphate dehydrogenase YP_002271370.1 2842171 R 444450 CDS YP_002271371.1 209397449 6966799 complement(2843259..2844614) 1 NC_011353.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827; PTS system galactitol-specific transporter subunit IIC 2844614 gatC 6966799 gatC Escherichia coli O157:H7 str. EC4115 PTS system galactitol-specific transporter subunit IIC YP_002271371.1 2843259 R 444450 CDS YP_002271372.1 209399554 6968419 complement(2844618..2844902) 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2844902 gatB 6968419 gatB Escherichia coli O157:H7 str. EC4115 PTS system galactitol-specific transporter subunit IIB YP_002271372.1 2844618 R 444450 CDS YP_002271373.1 209398381 6970692 complement(2844933..2845385) 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2845385 gatA 6970692 gatA Escherichia coli O157:H7 str. EC4115 PTS system galactitol-specific transporter subunit IIA YP_002271373.1 2844933 R 444450 CDS YP_002271374.1 209400959 6969424 complement(2845395..2846657) 1 NC_011353.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; tagatose-6-phosphate kinase 2846657 6969424 ECH74115_3074 Escherichia coli O157:H7 str. EC4115 tagatose-6-phosphate kinase YP_002271374.1 2845395 R 444450 CDS YP_002271375.1 209396937 6972197 complement(2846686..2847540) 1 NC_011353.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2847540 gatY 6972197 gatY Escherichia coli O157:H7 str. EC4115 tagatose-bisphosphate aldolase YP_002271375.1 2846686 R 444450 CDS YP_002271376.1 209396214 6967875 complement(2847839..2848891) 1 NC_011353.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2848891 fbaB 6967875 fbaB Escherichia coli O157:H7 str. EC4115 fructose-bisphosphate aldolase YP_002271376.1 2847839 R 444450 CDS YP_002271377.1 209398133 6967103 2849148..2850425 1 NC_011353.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside transporter 2850425 yegT 6967103 yegT Escherichia coli O157:H7 str. EC4115 nucleoside transporter YP_002271377.1 2849148 D 444450 CDS YP_002271378.1 209395786 6969155 2850422..2851426 1 NC_011353.1 identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase family protein 2851426 6969155 ECH74115_3078 Escherichia coli O157:H7 str. EC4115 ADP-ribosylglycohydrolase family protein YP_002271378.1 2850422 D 444450 CDS YP_002271379.1 209397619 6966642 2851423..2852388 1 NC_011353.1 identified by match to protein family HMM PF00294; kinase, PfkB family 2852388 6966642 ECH74115_3080 Escherichia coli O157:H7 str. EC4115 kinase, PfkB family YP_002271379.1 2851423 D 444450 CDS YP_002271380.1 209399375 6968600 complement(2852362..2853108) 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 2853108 6968600 ECH74115_3079 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002271380.1 2852362 R 444450 CDS YP_002271381.1 209396750 6970500 complement(2853160..2853978) 1 NC_011353.1 identified by match to protein family HMM PF01183; glycosyl hydrolase family 25 2853978 6970500 ECH74115_3081 Escherichia coli O157:H7 str. EC4115 glycosyl hydrolase family 25 YP_002271381.1 2853160 R 444450 CDS YP_002271382.1 209400323 6967677 complement(2854043..2854843) 1 NC_011353.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2854843 thiD 6967677 thiD Escherichia coli O157:H7 str. EC4115 phosphomethylpyrimidine kinase YP_002271382.1 2854043 R 444450 CDS YP_002271383.1 209395939 6971519 complement(2854840..2855628) 1 NC_011353.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2855628 thiM 6971519 thiM Escherichia coli O157:H7 str. EC4115 hydroxyethylthiazole kinase YP_002271383.1 2854840 R 444450 CDS YP_002271384.1 209396104 6966806 2856049..2856201 1 NC_011353.1 hypothetical protein 2856201 6966806 ECH74115_3085 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271384.1 2856049 D 444450 CDS YP_002271385.1 209397076 6966983 2857423..2857599 1 NC_011353.1 hypothetical protein 2857599 6966983 ECH74115_3086 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271385.1 2857423 D 444450 CDS YP_002271386.1 209398006 6968022 2857609..2857923 1 NC_011353.1 outer membrane protein 2857923 6968022 ECH74115_3087 Escherichia coli O157:H7 str. EC4115 outer membrane protein YP_002271386.1 2857609 D 444450 CDS YP_002271387.1 209398879 6969018 complement(2858033..2858305) 1 NC_011353.1 identified by match to protein family HMM PF02583; transcriptional repressor RcnR 2858305 6969018 ECH74115_3088 Escherichia coli O157:H7 str. EC4115 transcriptional repressor RcnR YP_002271387.1 2858033 R 444450 CDS YP_002271388.1 209397100 6969968 2858425..2859282 1 NC_011353.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2859282 rcnA 6969968 rcnA Escherichia coli O157:H7 str. EC4115 nickel/cobalt efflux protein RcnA YP_002271388.1 2858425 D 444450 CDS YP_002271389.1 209396065 6968048 2859500..2859838 1 NC_011353.1 hypothetical protein 2859838 6968048 ECH74115_3090 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271389.1 2859500 D 444450 CDS YP_002271390.1 209396961 6966944 complement(2859920..2860954) 1 NC_011353.1 type-1 fimbrial protein 2860954 6966944 ECH74115_3091 Escherichia coli O157:H7 str. EC4115 type-1 fimbrial protein YP_002271390.1 2859920 R 444450 CDS YP_002271391.1 209400432 6967900 complement(2860965..2863445) 1 NC_011353.1 identified by match to protein family HMM PF00577; fimbrial usher protein 2863445 6967900 ECH74115_3092 Escherichia coli O157:H7 str. EC4115 fimbrial usher protein YP_002271391.1 2860965 R 444450 CDS YP_002271392.1 209399857 6971634 complement(2863461..2864135) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; gram-negative pilus assembly chaperone 2864135 6971634 ECH74115_3093 Escherichia coli O157:H7 str. EC4115 gram-negative pilus assembly chaperone YP_002271392.1 2863461 R 444450 CDS YP_002271393.1 209397648 6971016 complement(2864223..2864765) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 2864765 6971016 ECH74115_3094 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002271393.1 2864223 R 444450 CDS YP_002271394.1 209398399 6968631 complement(2865057..2865218) 1 NC_011353.1 hypothetical protein 2865218 6968631 ECH74115_3095 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271394.1 2865057 R 444450 CDS YP_002271395.1 209398237 6969445 complement(2865600..2866709) 1 NC_011353.1 ATPase 2866709 6969445 ECH74115_3096 Escherichia coli O157:H7 str. EC4115 ATPase YP_002271395.1 2865600 R 444450 CDS YP_002271396.1 209397521 6969268 2866841..2868874 1 NC_011353.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2868874 metG 6969268 metG Escherichia coli O157:H7 str. EC4115 methionyl-tRNA synthetase YP_002271396.1 2866841 D 444450 CDS YP_002271397.1 209398923 6967527 2869933..2872824 1 NC_011353.1 identified by glimmer; hypothetical protein 2872824 6967527 ECH74115_3099 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271397.1 2869933 D 444450 CDS YP_002271398.1 209400731 6971228 2875832..2879461 1 NC_011353.1 molybdate metabolism regulator MolR-like protein 2879461 6971228 ECH74115_3102 Escherichia coli O157:H7 str. EC4115 molybdate metabolism regulator MolR-like protein YP_002271398.1 2875832 D 444450 CDS YP_002271399.1 209400144 6971955 2879523..2879840 1 NC_011353.1 identified by glimmer; hypothetical protein 2879840 6971955 ECH74115_3103 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271399.1 2879523 D 444450 CDS YP_002271400.1 209399579 6971330 complement(2880265..2880417) 1 NC_011353.1 identified by glimmer; hypothetical protein 2880417 6971330 ECH74115_3104 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271400.1 2880265 R 444450 CDS YP_002271401.1 209398941 6970719 2881081..2882169 1 NC_011353.1 identified by match to protein family HMM PF07728; AAA ATPase 2882169 6970719 ECH74115_3105 Escherichia coli O157:H7 str. EC4115 AAA ATPase YP_002271401.1 2881081 D 444450 CDS YP_002271402.1 209396016 6967339 2884452..2885588 1 NC_011353.1 identified by match to protein family HMM PF00092; match to protein family HMM PF05762; von Willebrand factor type A domain-containing protein 2885588 6967339 ECH74115_3108 Escherichia coli O157:H7 str. EC4115 von Willebrand factor type A domain-containing protein YP_002271402.1 2884452 D 444450 CDS YP_002271403.1 209397681 6966889 2885585..2887588 1 NC_011353.1 identified by match to protein family HMM PF04434; hypothetical protein 2887588 6966889 ECH74115_3109 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271403.1 2885585 D 444450 CDS YP_002271404.1 209396912 6968664 2887713..2888174 1 NC_011353.1 identified by match to protein family HMM PF06998; lipoprotein 2888174 6968664 ECH74115_3110 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002271404.1 2887713 D 444450 CDS YP_002271405.1 209396694 6967850 complement(2888216..2888686) 1 NC_011353.1 identified by match to protein family HMM PF07308; hypothetical protein 2888686 6967850 ECH74115_3111 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271405.1 2888216 R 444450 CDS YP_002271406.1 209395950 6967617 complement(2888733..2889452) 1 NC_011353.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2889452 6967617 ECH74115_3112 Escherichia coli O157:H7 str. EC4115 two-component response-regulatory protein YehT YP_002271406.1 2888733 R 444450 CDS YP_002271407.1 209398468 6966817 complement(2889449..2891134) 1 NC_011353.1 identified by match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 2891134 6966817 ECH74115_3113 Escherichia coli O157:H7 str. EC4115 sensor histidine kinase YP_002271407.1 2889449 R 444450 CDS YP_002271408.1 209399105 6969522 2891223..2891351 1 NC_011353.1 identified by glimmer; hypothetical protein 2891351 6969522 ECH74115_3114 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271408.1 2891223 D 444450 CDS YP_002271409.1 209399957 6970207 2891393..2891533 1 NC_011353.1 identified by glimmer; hypothetical protein 2891533 6970207 ECH74115_3115 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271409.1 2891393 D 444450 CDS YP_002271410.1 209400564 6971126 2891649..2891897 1 NC_011353.1 identified by match to protein family HMM PF06183; hypothetical protein 2891897 6971126 ECH74115_3116 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271410.1 2891649 D 444450 CDS YP_002271411.1 209396050 6971773 complement(2892265..2892534) 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 2892534 6971773 ECH74115_3117 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002271411.1 2892265 R 444450 CDS YP_002271412.1 209395988 6966927 complement(2892536..2893849) 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 2893849 6966927 ECH74115_3118 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002271412.1 2892536 R 444450 CDS YP_002271413.1 209400205 6966859 complement(2893914..2894513) 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 2894513 6966859 ECH74115_3119 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002271413.1 2893914 R 444450 CDS YP_002271414.1 209400993 6971393 complement(2894581..2898054) 1 NC_011353.1 identified by match to protein family HMM PF09327; hypothetical protein 2898054 6971393 ECH74115_3120 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271414.1 2894581 R 444450 CDS YP_002271415.1 209396221 6972235 complement(2898130..2898249) 1 NC_011353.1 identified by glimmer; hypothetical protein 2898249 6972235 ECH74115_3121 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271415.1 2898130 R 444450 CDS YP_002271416.1 209399803 6967111 complement(2898295..2898873) 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 2898873 6967111 ECH74115_3122 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002271416.1 2898295 R 444450 CDS YP_002271417.1 209397367 6970960 complement(2898870..2899505) 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 2899505 6970960 ECH74115_3123 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002271417.1 2898870 R 444450 CDS YP_002271418.1 209398072 6968334 complement(2899624..2900322) 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 2900322 6968334 ECH74115_3124 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002271418.1 2899624 R 444450 CDS YP_002271419.1 209398559 6969089 complement(2900322..2900651) 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 2900651 6969089 ECH74115_3125 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002271419.1 2900322 R 444450 CDS YP_002271420.1 209399313 6969619 complement(2900648..2903293) 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 2903293 6969619 ECH74115_3126 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002271420.1 2900648 R 444450 CDS YP_002271421.1 209396929 6970432 complement(2903337..2903645) 1 NC_011353.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715; phage tail assembly protein T 2903645 6970432 ECH74115_3127 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002271421.1 2903337 R 444450 CDS YP_002271422.1 209400386 6971528 complement(2904108..2904860) 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 2904860 6971528 ECH74115_3129 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002271422.1 2904108 R 444450 CDS YP_002271423.1 209399798 6971587 complement(2904868..2905266) 1 NC_011353.1 identified by match to protein family HMM PF06141; phage minor tail protein U 2905266 6971587 ECH74115_3130 Escherichia coli O157:H7 str. EC4115 phage minor tail protein U YP_002271423.1 2904868 R 444450 CDS YP_002271424.1 209399229 6970955 complement(2905279..2905902) 1 NC_011353.1 identified by match to protein family HMM PF06763; prophage minor tail protein Z 2905902 6970955 ECH74115_3131 Escherichia coli O157:H7 str. EC4115 prophage minor tail protein Z YP_002271424.1 2905279 R 444450 CDS YP_002271425.1 209398650 6970340 complement(2905905..2906153) 1 NC_011353.1 hypothetical protein 2906153 6970340 ECH74115_3132 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271425.1 2905905 R 444450 CDS YP_002271426.1 209398265 6969718 complement(2906179..2906505) 1 NC_011353.1 membrane protein 2906505 6969718 ECH74115_3133 Escherichia coli O157:H7 str. EC4115 membrane protein YP_002271426.1 2906179 R 444450 CDS YP_002271427.1 209397642 6969297 complement(2906593..2910063) 1 NC_011353.1 identified by match to protein family HMM PF00574; match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 2910063 6969297 ECH74115_3134 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002271427.1 2906593 R 444450 CDS YP_002271428.1 209396792 6968625 complement(2910063..2910275) 1 NC_011353.1 hypothetical protein 2910275 6968625 ECH74115_3135 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271428.1 2910063 R 444450 CDS YP_002271429.1 209396075 6967723 complement(2910272..2912395) 1 NC_011353.1 identified by match to protein family HMM PF05876; phage terminase large subunit 2912395 6967723 ECH74115_3136 Escherichia coli O157:H7 str. EC4115 phage terminase large subunit YP_002271429.1 2910272 R 444450 CDS YP_002271430.1 209398646 6966954 complement(2912392..2912868) 1 NC_011353.1 identified by match to protein family HMM PF07278; bacteriophage terminase, small subunit 2912868 6966954 ECH74115_3137 Escherichia coli O157:H7 str. EC4115 bacteriophage terminase, small subunit YP_002271430.1 2912392 R 444450 CDS YP_002271431.1 209397857 6969270 complement(2913324..2913791) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 2913791 6969270 ECH74115_3140 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002271431.1 2913324 R 444450 CDS YP_002271432.1 209397085 6968849 complement(2913799..2913945) 1 NC_011353.1 hypothetical protein 2913945 6968849 ECH74115_3141 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271432.1 2913799 R 444450 CDS YP_002271433.1 209399334 6968031 complement(2913945..2914514) 1 NC_011353.1 anti-repressor protein Ant 2914514 6968031 ECH74115_3142 Escherichia coli O157:H7 str. EC4115 anti-repressor protein Ant YP_002271433.1 2913945 R 444450 CDS YP_002271434.1 209397513 6970454 complement(2914785..2915318) 1 NC_011353.1 identified by match to protein family HMM PF00959; lysozyme 2915318 6970454 ECH74115_3143 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002271434.1 2914785 R 444450 CDS YP_002271435.1 209399267 6968486 complement(2915323..2915538) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 2915538 6968486 ECH74115_3144 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271435.1 2915323 R 444450 CDS YP_002271436.1 209398350 6970383 complement(2915616..2915861) 1 NC_011353.1 identified by match to protein family HMM PF05696; hypothetical protein 2915861 6970383 ECH74115_3145 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271436.1 2915616 R 444450 CDS YP_002271437.1 209400449 6969390 complement(2915902..2916081) 1 NC_011353.1 identified by match to protein family HMM PF07125; hypothetical protein 2916081 6969390 ECH74115_3146 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271437.1 2915902 R 444450 CDS YP_002271438.1 209396817 6971654 complement(2916218..2918164) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 2918164 6971654 ECH74115_3147 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271438.1 2916218 R 444450 CDS YP_002271439.1 209396076 6967749 2918405..2918551 1 NC_011353.1 hypothetical protein 2918551 6967749 ECH74115_3148 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271439.1 2918405 D 444450 CDS YP_002271440.1 209396738 6966955 2918593..2918712 1 NC_011353.1 identified by glimmer; hypothetical protein 2918712 6966955 ECH74115_3150 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271440.1 2918593 D 444450 CDS YP_002271441.1 209396181 6972395 complement(2918759..2919817) 1 NC_011353.1 identified by match to protein family HMM PF01555; DNA methylase 2919817 6972395 ECH74115_3151 Escherichia coli O157:H7 str. EC4115 DNA methylase YP_002271441.1 2918759 R 444450 CDS YP_002271442.1 209398187 6967067 complement(2919968..2920165) 1 NC_011353.1 hypothetical protein 2920165 6967067 ECH74115_3152 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271442.1 2919968 R 444450 CDS YP_002271443.1 209397668 6969215 complement(2920392..2921213) 1 NC_011353.1 identified by match to protein family HMM PF03589; antitermination protein Q 2921213 6969215 ECH74115_3153 Escherichia coli O157:H7 str. EC4115 antitermination protein Q YP_002271443.1 2920392 R 444450 CDS YP_002271444.1 209398314 6968651 complement(2921210..2921584) 1 NC_011353.1 identified by match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA 2921584 6968651 ECH74115_3154 Escherichia coli O157:H7 str. EC4115 crossover junction endodeoxyribonuclease RusA YP_002271444.1 2921210 R 444450 CDS YP_002271445.1 209397571 6969352 complement(2921597..2922646) 1 NC_011353.1 identified by match to protein family HMM PF06914; hypothetical protein 2922646 6969352 ECH74115_3155 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271445.1 2921597 R 444450 CDS YP_002271446.1 209398383 6970243 complement(2922996..2923253) 1 NC_011353.1 hypothetical protein 2923253 6970243 ECH74115_3157 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271446.1 2922996 R 444450 CDS YP_002271447.1 209400530 6969426 complement(2923875..2924024) 1 NC_011353.1 hypothetical protein 2924024 6969426 ECH74115_3158 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271447.1 2923875 R 444450 CDS YP_002271448.1 209399942 6971737 complement(2924095..2924457) 1 NC_011353.1 identified by match to protein family HMM PF04448; hypothetical protein 2924457 6971737 ECH74115_3159 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271448.1 2924095 R 444450 CDS YP_002271449.1 209396329 6971109 complement(2924454..2924825) 1 NC_011353.1 hypothetical protein 2924825 6971109 ECH74115_3160 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271449.1 2924454 R 444450 CDS YP_002271450.1 209398230 6967226 complement(2924861..2925073) 1 NC_011353.1 hypothetical protein 2925073 6967226 ECH74115_3161 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271450.1 2924861 R 444450 CDS YP_002271451.1 209399096 6969261 complement(2925122..2925478) 1 NC_011353.1 hypothetical protein 2925478 6969261 ECH74115_3162 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271451.1 2925122 R 444450 CDS YP_002271452.1 209398364 6970198 complement(2925535..2925930) 1 NC_011353.1 identified by match to protein family HMM PF06163; hypothetical protein 2925930 6970198 ECH74115_3163 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271452.1 2925535 R 444450 CDS YP_002271453.1 209399069 6969407 complement(2925946..2926716) 1 NC_011353.1 identified by match to protein family HMM PF07789; hypothetical protein 2926716 6969407 ECH74115_3164 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271453.1 2925946 R 444450 CDS YP_002271454.1 209398483 6970171 complement(2926751..2927173) 1 NC_011353.1 hypothetical protein 2927173 6970171 ECH74115_3165 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271454.1 2926751 R 444450 CDS YP_002271455.1 209400576 6969540 complement(2927205..2928245) 1 NC_011353.1 hypothetical protein 2928245 6969540 ECH74115_3166 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271455.1 2927205 R 444450 CDS YP_002271456.1 209399971 6971786 complement(2928217..2928708) 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 2928708 6971786 ECH74115_3167 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271456.1 2928217 R 444450 CDS YP_002271457.1 209396753 6971142 complement(2928752..2928979) 1 NC_011353.1 DNA-binding transcriptional regulator DicC 2928979 6971142 ECH74115_3168 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator DicC YP_002271457.1 2928752 R 444450 CDS YP_002271458.1 209396033 6967680 complement(2929085..2929291) 1 NC_011353.1 identified by glimmer; hypothetical protein 2929291 6967680 ECH74115_3169 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271458.1 2929085 R 444450 CDS YP_002271459.1 209399033 6966909 2929330..2929464 1 NC_011353.1 HTH-type transcriptional regulator DicA 2929464 6966909 ECH74115_3170 Escherichia coli O157:H7 str. EC4115 HTH-type transcriptional regulator DicA YP_002271459.1 2929330 D 444450 CDS YP_002271460.1 209398446 6970134 2929654..2929809 1 NC_011353.1 identified by match to protein family HMM PF07151; hypothetical protein 2929809 6970134 ECH74115_3171 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271460.1 2929654 D 444450 CDS YP_002271461.1 209400620 6969498 2929811..2929939 1 NC_011353.1 identified by glimmer; hypothetical protein 2929939 6969498 ECH74115_3172 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271461.1 2929811 D 444450 CDS YP_002271462.1 209399979 6971832 2929969..2930187 1 NC_011353.1 identified by glimmer; hypothetical protein 2930187 6971832 ECH74115_3173 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271462.1 2929969 D 444450 CDS YP_002271463.1 209396208 6971151 complement(2930191..2930355) 1 NC_011353.1 hypothetical protein 2930355 6971151 ECH74115_3174 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271463.1 2930191 R 444450 CDS YP_002271464.1 209396502 6972133 2930998..2931126 1 NC_011353.1 identified by match to protein family HMM PF07358; hypothetical protein 2931126 6972133 ECH74115_3176 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271464.1 2930998 D 444450 CDS YP_002271465.1 209395771 6967414 2931219..2933663 1 NC_011353.1 identified by match to protein family HMM PF00929; match to protein family HMM PF06630; exonuclease family protein 2933663 6967414 ECH74115_3177 Escherichia coli O157:H7 str. EC4115 exonuclease family protein YP_002271465.1 2931219 D 444450 CDS YP_002271466.1 209398502 6966627 2933954..2935084 1 NC_011353.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; site-specific recombinase, phage integrase family 2935084 6966627 ECH74115_3178 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002271466.1 2933954 D 444450 CDS YP_002271467.1 209397769 6969560 complement(2935130..2935246) 1 NC_011353.1 hypothetical protein 2935246 6969560 ECH74115_3179 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271467.1 2935130 R 444450 CDS YP_002271468.1 209399529 6968052 complement(2936108..2936698) 1 NC_011353.1 OspG 2936698 6968052 ECH74115_3181 Escherichia coli O157:H7 str. EC4115 OspG YP_002271468.1 2936108 R 444450 CDS YP_002271469.1 209398931 6970665 complement(2936874..2937377) 1 NC_011353.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 2937377 6970665 ECH74115_3182 Escherichia coli O157:H7 str. EC4115 IS1, transposase orfB YP_002271469.1 2936874 R 444450 CDS YP_002271470.1 209400673 6970025 complement(2937831..2938100) 1 NC_011353.1 prophage tail fiber C-terminus family protein 2938100 6970025 ECH74115_3183 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002271470.1 2937831 R 444450 CDS YP_002271471.1 209400777 6971892 complement(2938102..2938380) 1 NC_011353.1 identified by match to protein family HMM PF06820; tail fiber protein 2938380 6971892 ECH74115_3184 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002271471.1 2938102 R 444450 CDS YP_002271472.1 209395975 6967455 2939351..2939479 1 NC_011353.1 hypothetical protein 2939479 6967455 ECH74115_3186 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271472.1 2939351 D 444450 CDS YP_002271473.1 209397718 6966844 complement(2939480..2940079) 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 2940079 6966844 ECH74115_3187 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002271473.1 2939480 R 444450 CDS YP_002271474.1 209397747 6968703 complement(2940147..2943623) 1 NC_011353.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327; hypothetical protein 2943623 6968703 ECH74115_3188 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271474.1 2940147 R 444450 CDS YP_002271475.1 209397179 6968732 complement(2943699..2943818) 1 NC_011353.1 identified by glimmer; hypothetical protein 2943818 6968732 ECH74115_3189 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271475.1 2943699 R 444450 CDS YP_002271476.1 209400683 6968133 complement(2943864..2944442) 1 NC_011353.1 identified by match to protein family HMM PF06805; bacteriophage lambda tail assembly protein I 2944442 6968133 ECH74115_3190 Escherichia coli O157:H7 str. EC4115 bacteriophage lambda tail assembly protein I YP_002271476.1 2943864 R 444450 CDS YP_002271477.1 209398654 6971903 complement(2944439..2945074) 1 NC_011353.1 identified by match to protein family HMM PF00877; tail assembly protein 2945074 6971903 ECH74115_3191 Escherichia coli O157:H7 str. EC4115 tail assembly protein YP_002271477.1 2944439 R 444450 CDS YP_002271478.1 209399173 6969723 complement(2945193..2945891) 1 NC_011353.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600; phage minor tail protein L 2945891 6969723 ECH74115_3192 Escherichia coli O157:H7 str. EC4115 phage minor tail protein L YP_002271478.1 2945193 R 444450 CDS YP_002271479.1 209397124 6970281 complement(2945891..2946220) 1 NC_011353.1 identified by match to protein family HMM PF05939; phage minor tail protein 2946220 6970281 ECH74115_3193 Escherichia coli O157:H7 str. EC4115 phage minor tail protein YP_002271479.1 2945891 R 444450 CDS YP_002271480.1 209399937 6968073 complement(2946217..2948862) 1 NC_011353.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541; prophage tail length tape measure protein 2948862 6968073 ECH74115_3194 Escherichia coli O157:H7 str. EC4115 prophage tail length tape measure protein YP_002271480.1 2946217 R 444450 CDS YP_002271481.1 209400546 6971102 complement(2948906..2949190) 1 NC_011353.1 identified by match to protein family HMM TIGR01715; phage tail assembly protein T 2949190 6971102 ECH74115_3195 Escherichia coli O157:H7 str. EC4115 phage tail assembly protein T YP_002271481.1 2948906 R 444450 CDS YP_002271482.1 209398463 6971755 complement(2949241..2949663) 1 NC_011353.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674; phage minor tail protein G 2949663 6971755 ECH74115_3196 Escherichia coli O157:H7 str. EC4115 phage minor tail protein G YP_002271482.1 2949241 R 444450 CDS YP_002271483.1 209398977 6969516 complement(2949677..2950429) 1 NC_011353.1 identified by match to protein family HMM PF02368; major tail protein V 2950429 6969516 ECH74115_3197 Escherichia coli O157:H7 str. EC4115 major tail protein V YP_002271483.1 2949677 R 444450 CDS YP_002271484.1 209397664 6970076 complement(2950437..2950835) 1 NC_011353.1 identified by match to protein family HMM PF06141; phage minor tail protein U 2950835 6970076 ECH74115_3198 Escherichia coli O157:H7 str. EC4115 phage minor tail protein U YP_002271484.1 2950437 R 444450 CDS YP_002271485.1 209398253 6968647 complement(2950848..2951471) 1 NC_011353.1 identified by match to protein family HMM PF06763; prophage minor tail protein Z 2951471 6968647 ECH74115_3199 Escherichia coli O157:H7 str. EC4115 prophage minor tail protein Z YP_002271485.1 2950848 R 444450 CDS YP_002271486.1 209396450 6969285 complement(2951474..2951722) 1 NC_011353.1 hypothetical protein 2951722 6969285 ECH74115_3200 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271486.1 2951474 R 444450 CDS YP_002271487.1 209399845 6967360 complement(2951748..2952074) 1 NC_011353.1 membrane protein 2952074 6967360 ECH74115_3201 Escherichia coli O157:H7 str. EC4115 membrane protein YP_002271487.1 2951748 R 444450 CDS YP_002271488.1 209400945 6971002 complement(2952162..2954117) 1 NC_011353.1 identified by match to protein family HMM PF00574; Clp protease domain-containing protein 2954117 clpP 6971002 clpP Escherichia coli O157:H7 str. EC4115 Clp protease domain-containing protein YP_002271488.1 2952162 R 444450 CDS YP_002271489.1 209398345 6972182 complement(2954131..2955633) 1 NC_011353.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539; phage portal protein, lambda family 2955633 6972182 ECH74115_3203 Escherichia coli O157:H7 str. EC4115 phage portal protein, lambda family YP_002271489.1 2954131 R 444450 CDS YP_002271490.1 209396211 6969385 complement(2955633..2955845) 1 NC_011353.1 hypothetical protein 2955845 6969385 ECH74115_3204 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271490.1 2955633 R 444450 CDS YP_002271491.1 209400368 6967100 complement(2955842..2957965) 1 NC_011353.1 identified by match to protein family HMM PF05876; phage terminase large subunit 2957965 6967100 ECH74115_3205 Escherichia coli O157:H7 str. EC4115 phage terminase large subunit YP_002271491.1 2955842 R 444450 CDS YP_002271492.1 209400290 6971567 complement(2957962..2958438) 1 NC_011353.1 identified by match to protein family HMM PF07278; bacteriophage terminase, small subunit 2958438 6971567 ECH74115_3206 Escherichia coli O157:H7 str. EC4115 bacteriophage terminase, small subunit YP_002271492.1 2957962 R 444450 CDS YP_002271493.1 209399542 6971484 complement(2958851..2959318) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 2959318 6971484 ECH74115_3207 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002271493.1 2958851 R 444450 CDS YP_002271494.1 209399434 6970678 complement(2959617..2960150) 1 NC_011353.1 identified by match to protein family HMM PF00959; lysozyme 2960150 6970678 ECH74115_3208 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002271494.1 2959617 R 444450 CDS YP_002271495.1 209398711 6970562 complement(2960187..2960744) 1 NC_011353.1 hypothetical protein 2960744 6970562 ECH74115_3209 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271495.1 2960187 R 444450 CDS YP_002271496.1 209395782 6969783 complement(2960748..2960963) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 2960963 6969783 ECH74115_3210 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271496.1 2960748 R 444450 CDS YP_002271497.1 209396366 6966638 complement(2961041..2961286) 1 NC_011353.1 identified by match to protein family HMM PF05696; hypothetical protein 2961286 6966638 ECH74115_3211 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271497.1 2961041 R 444450 CDS YP_002271498.1 209397326 6967268 complement(2961327..2961506) 1 NC_011353.1 identified by match to protein family HMM PF07125; hypothetical protein 2961506 6967268 ECH74115_3212 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271498.1 2961327 R 444450 CDS YP_002271499.1 209400458 6968290 complement(2961519..2961644) 1 NC_011353.1 hypothetical protein 2961644 6968290 ECH74115_3213 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271499.1 2961519 R 444450 CDS YP_002271500.1 209398441 6971663 complement(2961641..2963587) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 2963587 6971663 ECH74115_3214 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271500.1 2961641 R 444450 CDS YP_002271501.1 209400533 6971045 complement(2964795..2965229) 1 NC_011353.1 identified by match to protein family HMM PF06530; antitermination protein Q 2965229 6971045 ECH74115_3220 Escherichia coli O157:H7 str. EC4115 antitermination protein Q YP_002271501.1 2964795 R 444450 CDS YP_002271502.1 209396087 6971740 complement(2965315..2965452) 1 NC_011353.1 hypothetical protein 2965452 6971740 ECH74115_3221 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271502.1 2965315 R 444450 CDS YP_002271503.1 209396970 6966966 complement(2965452..2965814) 1 NC_011353.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 2965814 rusA 6966966 rusA Escherichia coli O157:H7 str. EC4115 endodeoxyribonuclease RUS YP_002271503.1 2965452 R 444450 CDS YP_002271504.1 209398004 6967910 complement(2965811..2966101) 1 NC_011353.1 identified by match to protein family HMM PF07102; hypothetical protein 2966101 6967910 ECH74115_3223 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271504.1 2965811 R 444450 CDS YP_002271505.1 209398423 6969016 complement(2966264..2966719) 1 NC_011353.1 DLP12 prophage; hypothetical protein 2966719 6969016 ECH74115_3224 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271505.1 2966264 R 444450 CDS YP_002271506.1 209398795 6969471 complement(2966934..2967731) 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2967731 6969471 ECH74115_3225 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002271506.1 2966934 R 444450 CDS YP_002271507.1 209399881 6969874 2967908..2968030 1 NC_011353.1 hypothetical protein 2968030 6969874 ECH74115_3226 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271507.1 2967908 D 444450 CDS YP_002271508.1 209400302 6971042 complement(2968757..2970283) 1 NC_011353.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; recombinase family protein 2970283 6971042 ECH74115_3227 Escherichia coli O157:H7 str. EC4115 recombinase family protein YP_002271508.1 2968757 R 444450 CDS YP_002271509.1 209400746 6971497 complement(2970540..2970872) 1 NC_011353.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 2970872 emrE 6971497 emrE Escherichia coli O157:H7 str. EC4115 multidrug efflux protein YP_002271509.1 2970540 R 444450 CDS YP_002271510.1 209397103 6971971 complement(2970940..2971242) 1 NC_011353.1 hypothetical protein 2971242 6971971 ECH74115_3229 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271510.1 2970940 R 444450 CDS YP_002271511.1 209398189 6968051 complement(2971239..2971676) 1 NC_011353.1 identified by match to protein family HMM PF06992; replication protein P 2971676 6968051 ECH74115_3230 Escherichia coli O157:H7 str. EC4115 replication protein P YP_002271511.1 2971239 R 444450 CDS YP_002271512.1 209398616 6969217 2971731..2972057 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 2972057 6969217 ECH74115_3231 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271512.1 2971731 D 444450 CDS YP_002271513.1 209399029 6969679 2972054..2972944 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 2972944 6969679 ECH74115_3232 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271513.1 2972054 D 444450 CDS YP_002271514.1 209400638 6971037 complement(2973250..2974254) 1 NC_011353.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; phage replication protein O 2974254 6971037 ECH74115_3234 Escherichia coli O157:H7 str. EC4115 phage replication protein O YP_002271514.1 2973250 R 444450 CDS YP_002271515.1 209396296 6971852 complement(2974266..2974805) 1 NC_011353.1 identified by match to protein family HMM PF06254; hypothetical protein 2974805 6971852 ECH74115_3235 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271515.1 2974266 R 444450 CDS YP_002271516.1 209396709 6967191 complement(2974875..2975105) 1 NC_011353.1 hypothetical protein 2975105 6967191 ECH74115_3236 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271516.1 2974875 R 444450 CDS YP_002271517.1 209395751 6967633 2975285..2975899 1 NC_011353.1 identified by match to protein family HMM PF00717; repressor protein 2975899 6967633 ECH74115_3237 Escherichia coli O157:H7 str. EC4115 repressor protein YP_002271517.1 2975285 D 444450 CDS YP_002271518.1 209397577 6966606 2975980..2977041 1 NC_011353.1 hypothetical protein 2977041 6966606 ECH74115_3238 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271518.1 2975980 D 444450 CDS YP_002271519.1 209397321 6968554 2977877..2978083 1 NC_011353.1 protein KiL 2978083 kiL 6968554 kiL Escherichia coli O157:H7 str. EC4115 protein KiL YP_002271519.1 2977877 D 444450 CDS YP_002271520.1 209397760 6968283 2978159..2978455 1 NC_011353.1 identified by match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 2978455 gam 6968283 gam Escherichia coli O157:H7 str. EC4115 host-nuclease inhibitor protein Gam YP_002271520.1 2978159 D 444450 CDS YP_002271521.1 209399455 6968747 2978461..2979246 1 NC_011353.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 2979246 bet 6968747 bet Escherichia coli O157:H7 str. EC4115 phage recombination protein Bet YP_002271521.1 2978461 D 444450 CDS YP_002271522.1 209399863 6970584 2979243..2979920 1 NC_011353.1 identified by match to protein family HMM PF09588; exonuclease 2979920 exo 6970584 exo Escherichia coli O157:H7 str. EC4115 exonuclease YP_002271522.1 2979243 D 444450 CDS YP_002271523.1 209397861 6971022 2980153..2980266 1 NC_011353.1 hypothetical protein 2980266 6971022 ECH74115_3243 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271523.1 2980153 D 444450 CDS YP_002271524.1 209398110 6968853 2980343..2980558 1 NC_011353.1 hypothetical protein 2980558 6968853 ECH74115_3244 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271524.1 2980343 D 444450 CDS YP_002271525.1 209399474 6969129 2980875..2981822 1 NC_011353.1 identified by match to protein family HMM PF04447; hypothetical protein 2981822 6969129 ECH74115_3245 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271525.1 2980875 D 444450 CDS YP_002271526.1 209399992 6970898 2983236..2983379 1 NC_011353.1 hypothetical protein 2983379 6970898 ECH74115_3249 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271526.1 2983236 D 444450 CDS YP_002271527.1 209396576 6971164 2983650..2983790 1 NC_011353.1 identified by match to protein family HMM PF06806; excisionase 2983790 6971164 ECH74115_3250 Escherichia coli O157:H7 str. EC4115 excisionase YP_002271527.1 2983650 D 444450 CDS YP_002271528.1 209395928 6967490 2983824..2985110 1 NC_011353.1 identified by match to protein family HMM PF00589; Int protein 2985110 6967490 ECH74115_3251 Escherichia coli O157:H7 str. EC4115 Int protein YP_002271528.1 2983824 D 444450 CDS YP_002271529.1 209396177 6966795 2985185..2985832 1 NC_011353.1 hypothetical protein 2985832 6966795 ECH74115_3252 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271529.1 2985185 D 444450 CDS YP_002271530.1 209396328 6967063 complement(2985980..2986711) 1 NC_011353.1 identified by match to protein family HMM PF00528; ABC transporter quaternary amine uptake (QAT) family, permease 2986711 6967063 ECH74115_3253 Escherichia coli O157:H7 str. EC4115 ABC transporter quaternary amine uptake (QAT) family, permease YP_002271530.1 2985980 R 444450 CDS YP_002271531.1 209398032 6967225 complement(2986716..2987642) 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter quaternary amine uptake (QAT) family, ATP-binding protein 2987642 6967225 ECH74115_3254 Escherichia coli O157:H7 str. EC4115 ABC transporter quaternary amine uptake (QAT) family, ATP-binding protein YP_002271531.1 2986716 R 444450 CDS YP_002271532.1 209397432 6969045 complement(2987635..2988792) 1 NC_011353.1 identified by match to protein family HMM PF00528; ABC transporter quaternary amine uptake (QAT) family, permease 2988792 6969045 ECH74115_3255 Escherichia coli O157:H7 str. EC4115 ABC transporter quaternary amine uptake (QAT) family, permease YP_002271532.1 2987635 R 444450 CDS YP_002271533.1 209399202 6968401 complement(2988799..2989716) 1 NC_011353.1 identified by match to protein family HMM PF04069; ABC transporter quaternary amine uptake transporter (QAT) family, substrate-binding protein 2989716 6968401 ECH74115_3256 Escherichia coli O157:H7 str. EC4115 ABC transporter quaternary amine uptake transporter (QAT) family, substrate-binding protein YP_002271533.1 2988799 R 444450 CDS YP_002271534.1 209399209 6970310 complement(2989968..2992265) 1 NC_011353.1 identified by match to protein family HMM PF00933; match to protein family HMM PF01915; beta-glucosidase, periplasmic 2992265 bglX 6970310 bglX Escherichia coli O157:H7 str. EC4115 beta-glucosidase, periplasmic YP_002271534.1 2989968 R 444450 CDS YP_002271535.1 209398595 6970318 2992266..2992424 1 NC_011353.1 identified by glimmer; hypothetical protein 2992424 6970318 ECH74115_3258 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271535.1 2992266 D 444450 CDS YP_002271536.1 209400328 6969656 2992461..2994176 1 NC_011353.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2994176 dld 6969656 dld Escherichia coli O157:H7 str. EC4115 D-lactate dehydrogenase YP_002271536.1 2992461 D 444450 CDS YP_002271537.1 209396832 6971524 complement(2994214..2995155) 1 NC_011353.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2995155 pbpG 6971524 pbpG Escherichia coli O157:H7 str. EC4115 D-alanyl-D-alanine endopeptidase YP_002271537.1 2994214 R 444450 CDS YP_002271538.1 209396981 6967765 complement(2995320..2995931) 1 NC_011353.1 identified by match to protein family HMM PF06930; hypothetical protein 2995931 6967765 ECH74115_3261 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271538.1 2995320 R 444450 CDS YP_002271539.1 209396851 6967922 2996077..2996655 1 NC_011353.1 identified by match to protein family HMM PF09335; hypothetical protein 2996655 6967922 ECH74115_3263 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271539.1 2996077 D 444450 CDS YP_002271540.1 209396096 6967784 complement(2996646..2996759) 1 NC_011353.1 hypothetical protein 2996759 6967784 ECH74115_3262 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271540.1 2996646 R 444450 CDS YP_002271541.1 209396086 6966975 complement(2996785..2997546) 1 NC_011353.1 identified by match to protein family HMM PF00106; acetoin dehydrogenase 2997546 6966975 ECH74115_3264 Escherichia coli O157:H7 str. EC4115 acetoin dehydrogenase YP_002271541.1 2996785 R 444450 CDS YP_002271542.1 209398358 6966965 complement(2997599..2999035) 1 NC_011353.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2999035 6966965 ECH74115_3265 Escherichia coli O157:H7 str. EC4115 multidrug resistance outer membrane protein MdtQ YP_002271542.1 2997599 R 444450 CDS YP_002271543.1 209400918 6969399 complement(2999730..3000680) 1 NC_011353.1 identified by match to protein family HMM PF01207; tRNA-dihydrouridine synthase C 3000680 6969399 ECH74115_3266 Escherichia coli O157:H7 str. EC4115 tRNA-dihydrouridine synthase C YP_002271543.1 2999730 R 444450 CDS YP_002271544.1 209397299 6972154 complement(3000839..3002032) 1 NC_011353.1 catalyzes the formation of catechol from salicylate; salicylate hydroxylase 3002032 6972154 ECH74115_3267 Escherichia coli O157:H7 str. EC4115 salicylate hydroxylase YP_002271544.1 3000839 R 444450 CDS YP_002271545.1 209399225 6968260 complement(3002047..3002691) 1 NC_011353.1 identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262; maleylacetoacetate isomerase 3002691 maiA 6968260 maiA Escherichia coli O157:H7 str. EC4115 maleylacetoacetate isomerase YP_002271545.1 3002047 R 444450 CDS YP_002271546.1 209400558 6970336 complement(3002700..3003401) 1 NC_011353.1 identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase family protein 3003401 6970336 ECH74115_3269 Escherichia coli O157:H7 str. EC4115 fumarylacetoacetate hydrolase family protein YP_002271546.1 3002700 R 444450 CDS YP_002271547.1 209399809 6971767 complement(3003416..3004444) 1 NC_011353.1 identified by match to protein family HMM PF07883; match to protein family HMM TIGR02272; gentisate 1,2-dioxygenase 3004444 gtdA 6971767 gtdA Escherichia coli O157:H7 str. EC4115 gentisate 1,2-dioxygenase YP_002271547.1 3003416 R 444450 CDS YP_002271548.1 209398712 6970966 complement(3004456..3005814) 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 3005814 6970966 ECH74115_3271 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002271548.1 3004456 R 444450 CDS YP_002271549.1 209398611 6969784 3005941..3006849 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3006849 6969784 ECH74115_3272 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002271549.1 3005941 D 444450 CDS YP_002271550.1 209399235 6969674 3006980..3007378 1 NC_011353.1 identified by match to protein family HMM PF03788; hypothetical protein 3007378 6969674 ECH74115_3273 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271550.1 3006980 D 444450 CDS YP_002271551.1 209399430 6970346 3007375..3008070 1 NC_011353.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659; hypothetical protein 3008070 6970346 ECH74115_3274 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271551.1 3007375 D 444450 CDS YP_002271552.1 209397721 6970558 3008200..3009084 1 NC_011353.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 3009084 cdd 6970558 cdd Escherichia coli O157:H7 str. EC4115 cytidine deaminase YP_002271552.1 3008200 D 444450 CDS YP_002271553.1 209395911 6968706 3009234..3009953 1 NC_011353.1 identified by match to protein family HMM PF02698; hypothetical protein 3009953 sanA 6968706 sanA Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271553.1 3009234 D 444450 CDS YP_002271554.1 209400436 6966778 3009956..3010195 1 NC_011353.1 hypothetical protein 3010195 6966778 ECH74115_3277 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271554.1 3009956 D 444450 CDS YP_002271555.1 209398540 6971638 3010389..3011627 1 NC_011353.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 3011627 6971638 ECH74115_3278 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002271555.1 3010389 D 444450 CDS YP_002271556.1 209396337 6969599 3011621..3012856 1 NC_011353.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 3012856 6969599 ECH74115_3279 Escherichia coli O157:H7 str. EC4115 dihydropyrimidine dehydrogenase YP_002271556.1 3011621 D 444450 CDS YP_002271557.1 209399716 6967236 3012902..3013021 1 NC_011353.1 hypothetical protein 3013021 6967236 ECH74115_3280 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271557.1 3012902 D 444450 CDS YP_002271558.1 209397480 6970868 complement(3013099..3014109) 1 NC_011353.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 3014109 mglC 6970868 mglC Escherichia coli O157:H7 str. EC4115 beta-methylgalactoside transporter inner membrane protein YP_002271558.1 3013099 R 444450 CDS YP_002271559.1 209397905 6968451 complement(3014125..3015645) 1 NC_011353.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 3015645 mglA 6968451 mglA Escherichia coli O157:H7 str. EC4115 galactose/methyl galaxtoside transporter ATP-binding protein YP_002271559.1 3014125 R 444450 CDS YP_002271560.1 209400859 6968903 complement(3015706..3016704) 1 NC_011353.1 identified by match to protein family HMM PF00532; galactose ABC transporter periplasmic galactose-binding protein 3016704 mglB 6968903 mglB Escherichia coli O157:H7 str. EC4115 galactose ABC transporter periplasmic galactose-binding protein YP_002271560.1 3015706 R 444450 CDS YP_002271561.1 209399775 6972090 3016776..3016934 1 NC_011353.1 identified by glimmer; hypothetical protein 3016934 6972090 ECH74115_3284 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271561.1 3016776 D 444450 CDS YP_002271562.1 209396373 6970931 complement(3016983..3018023) 1 NC_011353.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 3018023 galS 6970931 galS Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator GalS YP_002271562.1 3016983 R 444450 CDS YP_002271563.1 209395998 6967278 complement(3018165..3019322) 1 NC_011353.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235; hypothetical protein 3019322 6967278 ECH74115_3286 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271563.1 3018165 R 444450 CDS YP_002271564.1 209398010 6966870 complement(3019339..3020007) 1 NC_011353.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 3020007 folE 6966870 folE Escherichia coli O157:H7 str. EC4115 GTP cyclohydrolase I YP_002271564.1 3019339 R 444450 CDS YP_002271565.1 209400188 6970595 3020265..3021101 1 NC_011353.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase 3021101 fghA1 6970595 fghA1 Escherichia coli O157:H7 str. EC4115 S-formylglutathione hydrolase YP_002271565.1 3020265 D 444450 CDS YP_002271566.1 209396460 6971375 complement(3021133..3023112) 1 NC_011353.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 3023112 cirA 6971375 cirA Escherichia coli O157:H7 str. EC4115 colicin I receptor YP_002271566.1 3021133 R 444450 CDS YP_002271567.1 209395763 6967371 3023253..3023387 1 NC_011353.1 identified by glimmer; hypothetical protein 3023387 6967371 ECH74115_3291 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271567.1 3023253 D 444450 CDS YP_002271568.1 209397992 6966618 complement(3023404..3024873) 1 NC_011353.1 identified by match to protein family HMM PF00324; lysine transporter 3024873 lysP 6966618 lysP Escherichia coli O157:H7 str. EC4115 lysine transporter YP_002271568.1 3023404 R 444450 CDS YP_002271569.1 209399117 6969003 complement(3025078..3025959) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 3025959 6969003 ECH74115_3293 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002271569.1 3025078 R 444450 CDS YP_002271570.1 209398351 6970219 3026058..3027107 1 NC_011353.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698; hypothetical protein 3027107 6970219 ECH74115_3294 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271570.1 3026058 D 444450 CDS YP_002271571.1 209400626 6969391 3027181..3028038 1 NC_011353.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 3028038 nfo 6969391 nfo Escherichia coli O157:H7 str. EC4115 endonuclease IV YP_002271571.1 3027181 D 444450 CDS YP_002271572.1 209400797 6971839 3028041..3029129 1 NC_011353.1 identified by match to protein family HMM PF00294; hypothetical protein 3029129 6971839 ECH74115_3296 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271572.1 3028041 D 444450 CDS YP_002271573.1 209396884 6972024 complement(3029185..3030435) 1 NC_011353.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC family 3030435 6972024 ECH74115_3297 Escherichia coli O157:H7 str. EC4115 nucleoside transporter NupC family YP_002271573.1 3029185 R 444450 CDS YP_002271574.1 209396314 6967821 complement(3030535..3031476) 1 NC_011353.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 3031476 rihB 6967821 rihB Escherichia coli O157:H7 str. EC4115 ribonucleoside hydrolase 2 YP_002271574.1 3030535 R 444450 CDS YP_002271575.1 209398067 6967210 3031606..3032304 1 NC_011353.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 3032304 nsr 6967210 nsr Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator YeiL YP_002271575.1 3031606 D 444450 CDS YP_002271576.1 209397477 6969084 complement(3032375..3033625) 1 NC_011353.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC family 3033625 6969084 ECH74115_3300 Escherichia coli O157:H7 str. EC4115 nucleoside transporter NupC family YP_002271576.1 3032375 R 444450 CDS YP_002271577.1 209399243 6968448 complement(3033719..3034657) 1 NC_011353.1 identified by match to protein family HMM PF04227; indigoidine synthase A like protein 3034657 6968448 ECH74115_3301 Escherichia coli O157:H7 str. EC4115 indigoidine synthase A like protein YP_002271577.1 3033719 R 444450 CDS YP_002271578.1 209398647 6970355 complement(3034645..3035586) 1 NC_011353.1 identified by match to protein family HMM PF00294; hypothetical protein 3035586 6970355 ECH74115_3302 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271578.1 3034645 R 444450 CDS YP_002271579.1 209399216 6969714 complement(3036010..3037701) 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 3037701 fruA 6969714 fruA Escherichia coli O157:H7 str. EC4115 PTS system fructose-specific transporter subunit IIBC YP_002271579.1 3036010 R 444450 CDS YP_002271580.1 209396003 6970326 complement(3037718..3038656) 1 NC_011353.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 3038656 fruK 6970326 fruK Escherichia coli O157:H7 str. EC4115 1-phosphofructokinase YP_002271580.1 3037718 R 444450 CDS YP_002271581.1 209400685 6966875 complement(3038656..3039786) 1 NC_011353.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; PTS system fructose-specific transporter subunit IIA/HPr protein 3039786 fruB 6966875 fruB Escherichia coli O157:H7 str. EC4115 PTS system fructose-specific transporter subunit IIA/HPr protein YP_002271581.1 3038656 R 444450 CDS YP_002271582.1 209397420 6971905 3039952..3040083 1 NC_011353.1 hypothetical protein 3040083 6971905 ECH74115_3306 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271582.1 3039952 D 444450 CDS YP_002271583.1 209398972 6968389 3040154..3041335 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899; sugar efflux transporter B 3041335 setB 6968389 setB Escherichia coli O157:H7 str. EC4115 sugar efflux transporter B YP_002271583.1 3040154 D 444450 CDS YP_002271584.1 209396849 6970071 complement(3041332..3041718) 1 NC_011353.1 hypothetical protein 3041718 6970071 ECH74115_3307 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271584.1 3041332 R 444450 CDS YP_002271585.1 209400095 6967782 3041741..3042313 1 NC_011353.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 3042313 6967782 ECH74115_3309 Escherichia coli O157:H7 str. EC4115 elongation factor P YP_002271585.1 3041741 D 444450 CDS YP_002271586.1 209396686 6971277 3042536..3044002 1 NC_011353.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase family protein 3044002 6971277 ECH74115_3310 Escherichia coli O157:H7 str. EC4115 mannitol dehydrogenase family protein YP_002271586.1 3042536 D 444450 CDS YP_002271587.1 209395981 6967608 3044120..3045106 1 NC_011353.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683; CobW/P47K family protein 3045106 6967608 ECH74115_3311 Escherichia coli O157:H7 str. EC4115 CobW/P47K family protein YP_002271587.1 3044120 D 444450 CDS YP_002271588.1 209399236 6966851 3045145..3045858 1 NC_011353.1 identified by match to protein family HMM PF01569; PAP2 family protein 3045858 6966851 ECH74115_3312 Escherichia coli O157:H7 str. EC4115 PAP2 family protein YP_002271588.1 3045145 D 444450 CDS YP_002271589.1 209398438 6970347 3046271..3046837 1 NC_011353.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 3046837 spr 6970347 spr Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein YP_002271589.1 3046271 D 444450 CDS YP_002271590.1 209397294 6969490 3047081..3048574 1 NC_011353.1 identified by match to protein family HMM PF00563; hypothetical protein 3048574 6969490 ECH74115_3314 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271590.1 3047081 D 444450 CDS YP_002271591.1 209399185 6968255 3048656..3050470 1 NC_011353.1 identified by match to protein family HMM PF00496; ABC transporter periplasmic solute-binding protein 3050470 6968255 ECH74115_3315 Escherichia coli O157:H7 str. EC4115 ABC transporter periplasmic solute-binding protein YP_002271591.1 3048656 D 444450 CDS YP_002271592.1 209396226 6970293 3050471..3051565 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 3051565 6970293 ECH74115_3316 Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002271592.1 3050471 D 444450 CDS YP_002271593.1 209398171 6967116 3051565..3052590 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00528; ABC transporter permease 3052590 6967116 ECH74115_3317 Escherichia coli O157:H7 str. EC4115 ABC transporter permease YP_002271593.1 3051565 D 444450 CDS YP_002271594.1 209396920 6969196 3052592..3054181 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3054181 6969196 ECH74115_3318 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002271594.1 3052592 D 444450 CDS YP_002271595.1 209396240 6967858 complement(3054185..3054529) 1 NC_011353.1 hypothetical protein 3054529 6967858 ECH74115_3319 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271595.1 3054185 R 444450 CDS YP_002271596.1 209398488 6967131 complement(3054862..3056052) 1 NC_011353.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 3056052 bcr 6967131 bcr Escherichia coli O157:H7 str. EC4115 bicyclomycin/multidrug efflux system protein YP_002271596.1 3054862 R 444450 CDS YP_002271597.1 209400555 6969545 complement(3056080..3056775) 1 NC_011353.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 3056775 rsuA 6969545 rsuA Escherichia coli O157:H7 str. EC4115 16S rRNA pseudouridylate synthase A YP_002271597.1 3056080 R 444450 CDS YP_002271598.1 209398310 6971764 3056924..3058684 1 NC_011353.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; helicase 3058684 6971764 ECH74115_3322 Escherichia coli O157:H7 str. EC4115 helicase YP_002271598.1 3056924 D 444450 CDS YP_002271599.1 209398752 6969347 3058809..3059093 1 NC_011353.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3059093 6969347 ECH74115_3323 Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L25 YP_002271599.1 3058809 D 444450 CDS YP_002271600.1 209396716 6969828 complement(3059232..3060239) 1 NC_011353.1 identified by match to protein family HMM PF04245; nucleoid-associated protein NdpA 3060239 ndpA 6969828 ndpA Escherichia coli O157:H7 str. EC4115 nucleoid-associated protein NdpA YP_002271600.1 3059232 R 444450 CDS YP_002271601.1 209397277 6967642 complement(3060284..3060400) 1 NC_011353.1 identified by glimmer; hypothetical protein 3060400 6967642 ECH74115_3325 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271601.1 3060284 R 444450 CDS YP_002271602.1 209400633 6968238 3060421..3060648 1 NC_011353.1 identified by match to protein family HMM PF07208; hypothetical protein 3060648 6968238 ECH74115_3326 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271602.1 3060421 D 444450 CDS YP_002271603.1 209395728 6971847 3060668..3062428 1 NC_011353.1 identified by match to protein family HMM PF00884; sulfatase family protein 3062428 6971847 ECH74115_3327 Escherichia coli O157:H7 str. EC4115 sulfatase family protein YP_002271603.1 3060668 D 444450 CDS YP_002271604.1 209399094 6972434 complement(3062680..3065271) 1 NC_011353.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; autotransporter IS5K-containing 3065271 6972434 ECH74115_3329 Escherichia coli O157:H7 str. EC4115 autotransporter IS5K-containing YP_002271604.1 3062680 R 444450 CDS YP_002271605.1 209398167 6970196 3065591..3066238 1 NC_011353.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 3066238 narP 6970196 narP Escherichia coli O157:H7 str. EC4115 transcriptional regulator NarP YP_002271605.1 3065591 D 444450 CDS YP_002271606.1 209396277 6969192 complement(3066273..3067325) 1 NC_011353.1 identified by match to protein family HMM PF03918; cytochrome c-type biogenesis family protein 3067325 6969192 ECH74115_3331 Escherichia coli O157:H7 str. EC4115 cytochrome c-type biogenesis family protein YP_002271606.1 3066273 R 444450 CDS YP_002271607.1 209396865 6967171 complement(3067322..3067879) 1 NC_011353.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385; thiol:disulfide interchange protein DsbE 3067879 dsbE 6967171 dsbE Escherichia coli O157:H7 str. EC4115 thiol:disulfide interchange protein DsbE YP_002271607.1 3067322 R 444450 CDS YP_002271608.1 209399270 6967800 complement(3067876..3069819) 1 NC_011353.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF 3069819 ccmF 6967800 ccmF Escherichia coli O157:H7 str. EC4115 cytochrome c-type biogenesis protein CcmF YP_002271608.1 3067876 R 444450 CDS YP_002271609.1 209398572 6970386 complement(3069816..3070295) 1 NC_011353.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 3070295 ccmE 6970386 ccmE Escherichia coli O157:H7 str. EC4115 cytochrome c-type biogenesis protein CcmE YP_002271609.1 3069816 R 444450 CDS YP_002271610.1 209396036 6969633 complement(3070292..3070501) 1 NC_011353.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141; heme exporter protein D 3070501 ccmD 6969633 ccmD Escherichia coli O157:H7 str. EC4115 heme exporter protein D YP_002271610.1 3070292 R 444450 CDS YP_002271611.1 209398336 6966912 complement(3070498..3071235) 1 NC_011353.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein C 3071235 ccmC 6966912 ccmC Escherichia coli O157:H7 str. EC4115 heme exporter protein C YP_002271611.1 3070498 R 444450 CDS YP_002271612.1 209400228 6969376 complement(3071277..3071939) 1 NC_011353.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB 3071939 ccmB 6969376 ccmB Escherichia coli O157:H7 str. EC4115 heme exporter protein CcmB YP_002271612.1 3071277 R 444450 CDS YP_002271613.1 209396482 6971418 complement(3071936..3072553) 1 NC_011353.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 3072553 ccmA 6971418 ccmA Escherichia coli O157:H7 str. EC4115 cytochrome c biogenesis protein CcmA YP_002271613.1 3071936 R 444450 CDS YP_002271614.1 209398459 6967394 complement(3072572..3073174) 1 NC_011353.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 3073174 napC 6967394 napC Escherichia coli O157:H7 str. EC4115 cytochrome c-type protein NapC YP_002271614.1 3072572 R 444450 CDS YP_002271615.1 209400531 6969512 complement(3073184..3073633) 1 NC_011353.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 3073633 napB 6969512 napB Escherichia coli O157:H7 str. EC4115 citrate reductase cytochrome c-type subunit YP_002271615.1 3073184 R 444450 CDS YP_002271616.1 209397253 6971738 complement(3073630..3074493) 1 NC_011353.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 3074493 napH 6971738 napH Escherichia coli O157:H7 str. EC4115 quinol dehydrogenase membrane component YP_002271616.1 3073630 R 444450 CDS YP_002271617.1 209397349 6968211 complement(3074480..3075175) 1 NC_011353.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 3075175 napG 6968211 napG Escherichia coli O157:H7 str. EC4115 quinol dehydrogenase periplasmic component YP_002271617.1 3074480 R 444450 CDS YP_002271618.1 209399788 6968316 complement(3075182..3077668) 1 NC_011353.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 3077668 napA 6968316 napA Escherichia coli O157:H7 str. EC4115 nitrate reductase catalytic subunit YP_002271618.1 3075182 R 444450 CDS YP_002271619.1 209400362 6970945 complement(3077665..3077928) 1 NC_011353.1 identified by match to protein family HMM PF03927; assembly protein for periplasmic nitrate reductase 3077928 napD 6970945 napD Escherichia coli O157:H7 str. EC4115 assembly protein for periplasmic nitrate reductase YP_002271619.1 3077665 R 444450 CDS YP_002271620.1 209396222 6971560 complement(3077918..3078412) 1 NC_011353.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein 3078412 napF 6971560 napF Escherichia coli O157:H7 str. EC4115 ferredoxin-type protein YP_002271620.1 3077918 R 444450 CDS YP_002271621.1 209395852 6967112 3078521..3078685 1 NC_011353.1 identified by glimmer; hypothetical protein 3078685 6967112 ECH74115_3346 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271621.1 3078521 D 444450 CDS YP_002271622.1 209397421 6966710 3078819..3079307 1 NC_011353.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 3079307 eco 6966710 eco Escherichia coli O157:H7 str. EC4115 ecotin YP_002271622.1 3078819 D 444450 CDS YP_002271623.1 209398037 6968390 complement(3079457..3081103) 1 NC_011353.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 3081103 mqo 6968390 mqo Escherichia coli O157:H7 str. EC4115 malate:quinone oxidoreductase YP_002271623.1 3079457 R 444450 CDS YP_002271624.1 209399262 6969050 complement(3081321..3082964) 1 NC_011353.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component 3082964 6969050 ECH74115_3349 Escherichia coli O157:H7 str. EC4115 multidrug transporter membrane protein/ATP-binding component YP_002271624.1 3081321 R 444450 CDS YP_002271625.1 209398419 6970378 complement(3083040..3083690) 1 NC_011353.1 identified by match to protein family HMM PF03171; match to protein family HMM TIGR00568; alkylated DNA repair protein AlkB 3083690 alkB 6970378 alkB Escherichia coli O157:H7 str. EC4115 alkylated DNA repair protein AlkB YP_002271625.1 3083040 R 444450 CDS YP_002271626.1 209398796 6969466 complement(3083690..3084754) 1 NC_011353.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589; regulatory protein Ada 3084754 ada 6969466 ada Escherichia coli O157:H7 str. EC4115 regulatory protein Ada YP_002271626.1 3083690 R 444450 CDS YP_002271627.1 209399737 6969875 complement(3084828..3085883) 1 NC_011353.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 3085883 apbE 6969875 apbE Escherichia coli O157:H7 str. EC4115 thiamine biosynthesis lipoprotein ApbE YP_002271627.1 3084828 R 444450 CDS YP_002271628.1 209400412 6970891 complement(3085995..3087098) 1 NC_011353.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 3087098 ompC 6970891 ompC Escherichia coli O157:H7 str. EC4115 outer membrane porin protein C YP_002271628.1 3085995 R 444450 CDS YP_002271629.1 209399810 6972251 complement(3087490..3087615) 1 NC_011353.1 hypothetical protein 3087615 6972251 ECH74115_3354 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271629.1 3087490 R 444450 CDS YP_002271630.1 209400425 6970967 3087837..3090509 1 NC_011353.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 3090509 yojN 6970967 yojN Escherichia coli O157:H7 str. EC4115 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_002271630.1 3087837 D 444450 CDS YP_002271631.1 209399700 6971627 3090526..3091176 1 NC_011353.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 3091176 rcsB 6971627 rcsB Escherichia coli O157:H7 str. EC4115 transcriptional regulator RcsB YP_002271631.1 3090526 D 444450 CDS YP_002271632.1 209396281 6970850 complement(3091376..3094225) 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF09456; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 3094225 rcsC 6970850 rcsC Escherichia coli O157:H7 str. EC4115 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_002271632.1 3091376 R 444450 CDS YP_002271633.1 209398194 6967175 complement(3094500..3095276) 1 NC_011353.1 hypothetical protein 3095276 6967175 ECH74115_3359 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271633.1 3094500 R 444450 CDS YP_002271634.1 209398434 6970636 complement(3096931..3101367) 1 NC_011353.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin family protein 3101367 6970636 ECH74115_3362 Escherichia coli O157:H7 str. EC4115 alpha-2-macroglobulin family protein YP_002271634.1 3096931 R 444450 CDS YP_002271635.1 209400516 6969485 complement(3101469..3102092) 1 NC_011353.1 identified by match to protein family HMM PF06672; hypothetical protein 3102092 6969485 ECH74115_3363 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271635.1 3101469 R 444450 CDS YP_002271636.1 209396529 6971723 complement(3102089..3103687) 1 NC_011353.1 hypothetical protein 3103687 6971723 ECH74115_3364 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271636.1 3102089 R 444450 CDS YP_002271637.1 209395953 6967442 complement(3103925..3106552) 1 NC_011353.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 3106552 gyrA 6967442 gyrA Escherichia coli O157:H7 str. EC4115 DNA gyrase subunit A YP_002271637.1 3103925 R 444450 CDS YP_002271638.1 209397053 6966820 3106699..3107421 1 NC_011353.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 3107421 ubiG 6966820 ubiG Escherichia coli O157:H7 str. EC4115 3-demethylubiquinone-9 3-methyltransferase YP_002271638.1 3106699 D 444450 CDS YP_002271639.1 209396650 6967999 complement(3107562..3111266) 1 NC_011353.1 identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601; adhesin 3111266 6967999 ECH74115_3367 Escherichia coli O157:H7 str. EC4115 adhesin YP_002271639.1 3107562 R 444450 CDS YP_002271640.1 209398582 6967570 3112010..3114295 1 NC_011353.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3114295 nrdA 6967570 nrdA Escherichia coli O157:H7 str. EC4115 ribonucleotide-diphosphate reductase subunit alpha YP_002271640.1 3112010 D 444450 CDS YP_002271641.1 209398142 6969643 3114483..3115652 1 NC_011353.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 3115652 nrdB 6969643 nrdB Escherichia coli O157:H7 str. EC4115 ribonucleotide-diphosphate reductase subunit beta YP_002271641.1 3114483 D 444450 CDS YP_002271642.1 209399483 6969164 3115652..3115906 1 NC_011353.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 3115906 6969164 ECH74115_3370 Escherichia coli O157:H7 str. EC4115 2Fe-2S ferredoxin YP_002271642.1 3115652 D 444450 CDS YP_002271643.1 209398743 6970617 complement(3115960..3116610) 1 NC_011353.1 identified by match to protein family HMM PF06293; hypothetical protein 3116610 6970617 ECH74115_3371 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271643.1 3115960 R 444450 CDS YP_002271644.1 209400975 6969819 complement(3116691..3117881) 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 3117881 6969819 ECH74115_3372 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002271644.1 3116691 R 444450 CDS YP_002271645.1 209400196 6972215 3118033..3118911 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; hypothetical protein 3118911 6972215 ECH74115_3373 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271645.1 3118033 D 444450 CDS YP_002271646.1 209399829 6971383 3119065..3119196 1 NC_011353.1 identified by glimmer; hypothetical protein 3119196 6971383 ECH74115_3374 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271646.1 3119065 D 444450 CDS YP_002271647.1 209399603 6970986 3119375..3120445 1 NC_011353.1 hypothetical protein 3120445 6970986 ECH74115_3375 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271647.1 3119375 D 444450 CDS YP_002271648.1 209396883 6970744 complement(3120669..3121745) 1 NC_011353.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 3121745 glpQ 6970744 glpQ Escherichia coli O157:H7 str. EC4115 glycerophosphodiester phosphodiesterase YP_002271648.1 3120669 R 444450 CDS YP_002271649.1 209396305 6967820 complement(3121750..3123108) 1 NC_011353.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 3123108 glpT 6967820 glpT Escherichia coli O157:H7 str. EC4115 sn-glycerol-3-phosphate transporter YP_002271649.1 3121750 R 444450 CDS YP_002271650.1 209398048 6967200 3123381..3125009 1 NC_011353.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 3125009 glpA 6967200 glpA Escherichia coli O157:H7 str. EC4115 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002271650.1 3123381 D 444450 CDS YP_002271651.1 209397429 6969063 3124999..3126258 1 NC_011353.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 3126258 glpB 6969063 glpB Escherichia coli O157:H7 str. EC4115 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002271651.1 3124999 D 444450 CDS YP_002271652.1 209397793 6968398 3126255..3127445 1 NC_011353.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 3127445 glpC 6968398 glpC Escherichia coli O157:H7 str. EC4115 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002271652.1 3126255 D 444450 CDS YP_002271653.1 209397027 6968782 3127470..3127595 1 NC_011353.1 identified by glimmer; hypothetical protein 3127595 6968782 ECH74115_3381 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271653.1 3127470 D 444450 CDS YP_002271654.1 209399653 6967971 3127638..3128564 1 NC_011353.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 3128564 6967971 ECH74115_3382 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271654.1 3127638 D 444450 CDS YP_002271655.1 209395765 6969996 complement(3129425..3130183) 1 NC_011353.1 major facilitator superfamily protein 3130183 6969996 ECH74115_3384 Escherichia coli O157:H7 str. EC4115 major facilitator superfamily protein YP_002271655.1 3129425 R 444450 CDS YP_002271656.1 209400431 6966620 3130254..3130580 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 3130580 6966620 ECH74115_3385 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271656.1 3130254 D 444450 CDS YP_002271657.1 209400150 6971633 3130577..3131467 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 3131467 6971633 ECH74115_3386 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271657.1 3130577 D 444450 CDS YP_002271658.1 209399289 6971336 complement(3131470..3132027) 1 NC_011353.1 major facilitator family transporter 3132027 6971336 ECH74115_3387 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002271658.1 3131470 R 444450 CDS YP_002271659.1 209398974 6970405 complement(3132084..3133289) 1 NC_011353.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing protein 3133289 6970405 ECH74115_3388 Escherichia coli O157:H7 str. EC4115 mandelate racemase/muconate lactonizing protein YP_002271659.1 3132084 R 444450 CDS YP_002271660.1 209398097 6970073 complement(3133304..3134086) 1 NC_011353.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339; IclR family transcriptional regulator 3134086 6970073 ECH74115_3389 Escherichia coli O157:H7 str. EC4115 IclR family transcriptional regulator YP_002271660.1 3133304 R 444450 CDS YP_002271661.1 209395745 6969115 complement(3134306..3135508) 1 NC_011353.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200; competence damage-inducible protein A 3135508 6969115 ECH74115_3390 Escherichia coli O157:H7 str. EC4115 competence damage-inducible protein A YP_002271661.1 3134306 R 444450 CDS YP_002271662.1 209397943 6966600 complement(3135608..3136150) 1 NC_011353.1 identified by match to protein family HMM PF07437; YfaZ protein 3136150 yfaZ 6966600 yfaZ Escherichia coli O157:H7 str. EC4115 YfaZ protein YP_002271662.1 3135608 R 444450 CDS YP_002271663.1 209397634 6968946 3136492..3136854 1 NC_011353.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 3136854 6968946 ECH74115_3392 Escherichia coli O157:H7 str. EC4115 NUDIX family hydrolase YP_002271663.1 3136492 D 444450 CDS YP_002271664.1 209399570 6968616 complement(3136893..3137495) 1 NC_011353.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 3137495 6968616 ECH74115_3393 Escherichia coli O157:H7 str. EC4115 phosphoglycerate mutase family protein YP_002271664.1 3136893 R 444450 CDS YP_002271665.1 209397998 6970708 3137785..3138942 1 NC_011353.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 3138942 arnB 6970708 arnB Escherichia coli O157:H7 str. EC4115 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_002271665.1 3137785 D 444450 CDS YP_002271666.1 209398426 6969009 3138946..3139914 1 NC_011353.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 3139914 arnC 6969009 arnC Escherichia coli O157:H7 str. EC4115 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_002271666.1 3138946 D 444450 CDS YP_002271667.1 209399006 6969474 3139914..3141896 1 NC_011353.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 3141896 arnA 6969474 arnA Escherichia coli O157:H7 str. EC4115 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_002271667.1 3139914 D 444450 CDS YP_002271668.1 209399583 6970105 3141893..3142783 1 NC_011353.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase domain-containing protein 3142783 6970105 ECH74115_3397 Escherichia coli O157:H7 str. EC4115 polysaccharide deacetylase domain-containing protein YP_002271668.1 3141893 D 444450 CDS YP_002271669.1 209400163 6970723 3142783..3144435 1 NC_011353.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 3144435 arnT 6970723 arnT Escherichia coli O157:H7 str. EC4115 4-amino-4-deoxy-L-arabinose transferase YP_002271669.1 3142783 D 444450 CDS YP_002271670.1 209400684 6971349 3144432..3144767 1 NC_011353.1 identified by match to protein family HMM PF00893; SMR family multidrug resistance protein 3144767 6971349 ECH74115_3399 Escherichia coli O157:H7 str. EC4115 SMR family multidrug resistance protein YP_002271670.1 3144432 D 444450 CDS YP_002271671.1 209397509 6971904 3144767..3145153 1 NC_011353.1 hypothetical protein 3145153 6971904 ECH74115_3401 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271671.1 3144767 D 444450 CDS YP_002271672.1 209395927 6968481 complement(3145147..3145413) 1 NC_011353.1 polymyxin B resistance protein pmrD 3145413 pmrD 6968481 pmrD Escherichia coli O157:H7 str. EC4115 polymyxin B resistance protein pmrD YP_002271672.1 3145147 R 444450 CDS YP_002271673.1 209397084 6966794 complement(3145523..3146878) 1 NC_011353.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923; O-succinylbenzoic acid--CoA ligase 3146878 menE 6966794 menE Escherichia coli O157:H7 str. EC4115 O-succinylbenzoic acid--CoA ligase YP_002271673.1 3145523 R 444450 CDS YP_002271674.1 209397997 6968030 complement(3146875..3147837) 1 NC_011353.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 3147837 menC 6968030 menC Escherichia coli O157:H7 str. EC4115 O-succinylbenzoate synthase YP_002271674.1 3146875 R 444450 CDS YP_002271675.1 209399870 6969008 complement(3147837..3148694) 1 NC_011353.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 3148694 menB 6969008 menB Escherichia coli O157:H7 str. EC4115 naphthoate synthase YP_002271675.1 3147837 R 444450 CDS YP_002271676.1 209400623 6971029 complement(3148709..3149467) 1 NC_011353.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 3149467 6971029 ECH74115_3405 Escherichia coli O157:H7 str. EC4115 acyl-CoA thioester hydrolase YfbB YP_002271676.1 3148709 R 444450 CDS YP_002271677.1 209399910 6971835 complement(3149464..3151134) 1 NC_011353.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 3151134 menD 6971835 menD Escherichia coli O157:H7 str. EC4115 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002271677.1 3149464 R 444450 CDS YP_002271678.1 209400654 6971074 complement(3151223..3152518) 1 NC_011353.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase, menaquinone-specific 3152518 menF 6971074 menF Escherichia coli O157:H7 str. EC4115 isochorismate synthase, menaquinone-specific YP_002271678.1 3151223 R 444450 CDS YP_002271679.1 209398447 6971870 complement(3152597..3152902) 1 NC_011353.1 identified by match to protein family HMM PF05957; hypothetical protein 3152902 6971870 ECH74115_3408 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271679.1 3152597 R 444450 CDS YP_002271680.1 209397547 6969499 complement(3152957..3153418) 1 NC_011353.1 identified by match to protein family HMM PF00583; hypothetical protein 3153418 6969499 ECH74115_3409 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271680.1 3152957 R 444450 CDS YP_002271681.1 209398284 6968521 3153465..3154400 1 NC_011353.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 3154400 rnz 6968521 rnz Escherichia coli O157:H7 str. EC4115 ribonuclease Z YP_002271681.1 3153465 D 444450 CDS YP_002271682.1 209396055 6969318 complement(3154468..3154587) 1 NC_011353.1 hypothetical protein 3154587 6969318 ECH74115_3411 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271682.1 3154468 R 444450 CDS YP_002271683.1 209396764 6966932 3154591..3155811 1 NC_011353.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 3155811 6966932 ECH74115_3412 Escherichia coli O157:H7 str. EC4115 deubiquitinase YP_002271683.1 3154591 D 444450 CDS YP_002271684.1 209399997 6971014 3156943..3157446 1 NC_011353.1 identified by match to protein family HMM PF08974; hypothetical protein 3157446 6971014 ECH74115_3414 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271684.1 3156943 D 444450 CDS YP_002271685.1 209396747 6971170 complement(3157513..3158970) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 3158970 nuoN 6971170 nuoN Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit N YP_002271685.1 3157513 R 444450 CDS YP_002271686.1 209396119 6967673 complement(3158977..3160506) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 3160506 nuoM 6967673 nuoM Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit M YP_002271686.1 3158977 R 444450 CDS YP_002271687.1 209398279 6966999 complement(3160737..3162572) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 3162572 nuoL 6966999 nuoL Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit L YP_002271687.1 3160737 R 444450 CDS YP_002271688.1 209397713 6969312 complement(3162575..3162877) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 3162877 nuoK 6969312 nuoK Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit K YP_002271688.1 3162575 R 444450 CDS YP_002271689.1 209397133 6968698 complement(3162874..3163428) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 3163428 nuoJ 6968698 nuoJ Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit J YP_002271689.1 3162874 R 444450 CDS YP_002271690.1 209399174 6968082 complement(3163440..3163982) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 3163982 nuoI 6968082 nuoI Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit I YP_002271690.1 3163440 R 444450 CDS YP_002271691.1 209399728 6970282 complement(3163997..3164974) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 3164974 nuoH 6970282 nuoH Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit H YP_002271691.1 3163997 R 444450 CDS YP_002271692.1 209396671 6970881 complement(3164971..3167697) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 3167697 nuoG 6970881 nuoG Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit G YP_002271692.1 3164971 R 444450 CDS YP_002271693.1 209395949 6967592 complement(3167750..3169087) 1 NC_011353.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 3169087 nuoF 6967592 nuoF Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase I subunit F YP_002271693.1 3167750 R 444450 CDS YP_002271694.1 209399385 6966816 complement(3169084..3169584) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 3169584 nuoE 6966816 nuoE Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit E YP_002271694.1 3169084 R 444450 CDS YP_002271695.1 209398773 6970510 complement(3169587..3171389) 1 NC_011353.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; NADH:ubiquinone oxidoreductase subunit C/D 3171389 nuoC 6970510 nuoC Escherichia coli O157:H7 str. EC4115 NADH:ubiquinone oxidoreductase subunit C/D YP_002271695.1 3169587 R 444450 CDS YP_002271696.1 209400872 6969851 complement(3171483..3172145) 1 NC_011353.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3172145 6969851 ECH74115_3426 Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit B YP_002271696.1 3171483 R 444450 CDS YP_002271697.1 209400280 6972104 complement(3172161..3172604) 1 NC_011353.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 3172604 nuoA 6972104 nuoA Escherichia coli O157:H7 str. EC4115 NADH dehydrogenase subunit A YP_002271697.1 3172161 R 444450 CDS YP_002271698.1 209396956 6971473 complement(3173235..3174173) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator LrhA 3174173 lrhA 6971473 lrhA Escherichia coli O157:H7 str. EC4115 transcriptional regulator LrhA YP_002271698.1 3173235 R 444450 CDS YP_002271699.1 209395758 6967894 3175093..3176310 1 NC_011353.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 3176310 6967894 ECH74115_3429 Escherichia coli O157:H7 str. EC4115 aminotransferase AlaT YP_002271699.1 3175093 D 444450 CDS YP_002271700.1 209397835 6966613 3176394..3176993 1 NC_011353.1 identified by match to protein family HMM PF01966; hypothetical protein 3176993 yfbR 6966613 yfbR Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271700.1 3176394 D 444450 CDS YP_002271701.1 209398669 6968827 complement(3177052..3178884) 1 NC_011353.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808; TRAP transporter DctM-like membrane protein 3178884 6968827 ECH74115_3431 Escherichia coli O157:H7 str. EC4115 TRAP transporter DctM-like membrane protein YP_002271701.1 3177052 R 444450 CDS YP_002271702.1 209400370 6969739 complement(3178971..3179621) 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; phosphatase 3179621 yfbT 6969739 yfbT Escherichia coli O157:H7 str. EC4115 phosphatase YP_002271702.1 3178971 R 444450 CDS YP_002271703.1 209399770 6971569 complement(3179632..3180126) 1 NC_011353.1 identified by match to protein family HMM PF03887; hypothetical protein 3180126 6971569 ECH74115_3433 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271703.1 3179632 R 444450 CDS YP_002271704.1 209396966 6970926 complement(3180209..3180664) 1 NC_011353.1 identified by match to protein family HMM PF04217; hypothetical protein 3180664 6970926 ECH74115_3434 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271704.1 3180209 R 444450 CDS YP_002271705.1 209398019 6968225 3181002..3182204 1 NC_011353.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 3182204 ackA 6968225 ackA Escherichia coli O157:H7 str. EC4115 acetate kinase YP_002271705.1 3181002 D 444450 CDS YP_002271706.1 209398457 6969032 3182279..3184423 1 NC_011353.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 3184423 pta 6969032 pta Escherichia coli O157:H7 str. EC4115 phosphate acetyltransferase YP_002271706.1 3182279 D 444450 CDS YP_002271707.1 209399207 6969510 3184592..3186133 1 NC_011353.1 identified by match to protein family HMM PF03606; hypothetical protein 3186133 6969510 ECH74115_3438 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271707.1 3184592 D 444450 CDS YP_002271708.1 209400943 6970316 complement(3186166..3186708) 1 NC_011353.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 3186708 6970316 ECH74115_3439 Escherichia coli O157:H7 str. EC4115 NUDIX family hydrolase YP_002271708.1 3186166 R 444450 CDS YP_002271709.1 209400493 6972180 complement(3186766..3187317) 1 NC_011353.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase 3187317 6972180 ECH74115_3440 Escherichia coli O157:H7 str. EC4115 phosphodiesterase YP_002271709.1 3186766 R 444450 CDS YP_002271710.1 209397918 6971698 complement(3187373..3188017) 1 NC_011353.1 identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein 3188017 6971698 ECH74115_3441 Escherichia coli O157:H7 str. EC4115 glutathione S-transferase domain-containing protein YP_002271710.1 3187373 R 444450 CDS YP_002271711.1 209398828 6968917 3188153..3188800 1 NC_011353.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 3188800 6968917 ECH74115_3442 Escherichia coli O157:H7 str. EC4115 glutathione S-transferase YP_002271711.1 3188153 D 444450 CDS YP_002271712.1 209399151 6969911 3188857..3189219 1 NC_011353.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 3189219 folX 6969911 folX Escherichia coli O157:H7 str. EC4115 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_002271712.1 3188857 D 444450 CDS YP_002271713.1 209400621 6970258 3189240..3190133 1 NC_011353.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777; NAD dependent epimerase/dehydratase family protein 3190133 6970258 ECH74115_3444 Escherichia coli O157:H7 str. EC4115 NAD dependent epimerase/dehydratase family protein YP_002271713.1 3189240 D 444450 CDS YP_002271714.1 209396022 6971833 complement(3190181..3191071) 1 NC_011353.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 3191071 6971833 ECH74115_3445 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271714.1 3190181 R 444450 CDS YP_002271715.1 209396572 6966896 complement(3191268..3192041) 1 NC_011353.1 identified by match to protein family HMM PF00005; histidine/lysine/arginine/ornithine transporter subunit 3192041 hisP 6966896 hisP Escherichia coli O157:H7 str. EC4115 histidine/lysine/arginine/ornithine transporter subunit YP_002271715.1 3191268 R 444450 CDS YP_002271716.1 209398320 6967486 complement(3192049..3192765) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisM 3192765 hisM 6967486 hisM Escherichia coli O157:H7 str. EC4115 histidine ABC transporter permease HisM YP_002271716.1 3192049 R 444450 CDS YP_002271717.1 209398746 6969358 complement(3192762..3193448) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisQ 3193448 hisQ 6969358 hisQ Escherichia coli O157:H7 str. EC4115 histidine ABC transporter permease HisQ YP_002271717.1 3192762 R 444450 CDS YP_002271718.1 209398498 6969822 complement(3193538..3194320) 1 NC_011353.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; histidine ABC transporter periplasmic histidine-binding protein 3194320 hisJ 6969822 hisJ Escherichia coli O157:H7 str. EC4115 histidine ABC transporter periplasmic histidine-binding protein YP_002271718.1 3193538 R 444450 CDS YP_002271719.1 209399107 6969556 complement(3194541..3195323) 1 NC_011353.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; lysine-arginine-ornithine-binding periplasmic protein 3195323 argT 6969556 argT Escherichia coli O157:H7 str. EC4115 lysine-arginine-ornithine-binding periplasmic protein YP_002271719.1 3194541 R 444450 CDS YP_002271720.1 209397465 6970209 complement(3195589..3196158) 1 NC_011353.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3196158 ubiX 6970209 ubiX Escherichia coli O157:H7 str. EC4115 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002271720.1 3195589 R 444450 CDS YP_002271721.1 209397230 6968436 complement(3196253..3197770) 1 NC_011353.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 3197770 purF 6968436 purF Escherichia coli O157:H7 str. EC4115 amidophosphoribosyltransferase YP_002271721.1 3196253 R 444450 CDS YP_002271722.1 209398843 6968188 complement(3197807..3198295) 1 NC_011353.1 membrane protein required for colicin V production; colicin V production protein 3198295 cvpA 6968188 cvpA Escherichia coli O157:H7 str. EC4115 colicin V production protein YP_002271722.1 3197807 R 444450 CDS YP_002271723.1 209400893 6969927 complement(3198827..3199489) 1 NC_011353.1 identified by match to protein family HMM PF05036; hypothetical protein 3199489 6969927 ECH74115_3454 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271723.1 3198827 R 444450 CDS YP_002271724.1 209398810 6972127 complement(3199479..3200747) 1 NC_011353.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 3200747 folC 6972127 folC Escherichia coli O157:H7 str. EC4115 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_002271724.1 3199479 R 444450 CDS YP_002271725.1 209399397 6969890 complement(3200817..3201731) 1 NC_011353.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 3201731 accD 6969890 accD Escherichia coli O157:H7 str. EC4115 acetyl-CoA carboxylase subunit beta YP_002271725.1 3200817 R 444450 CDS YP_002271726.1 209399357 6970522 complement(3201887..3202546) 1 NC_011353.1 identified by match to protein family HMM PF09335; hypothetical protein 3202546 6970522 ECH74115_3457 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271726.1 3201887 R 444450 CDS YP_002271727.1 209397276 6970479 complement(3202629..3203441) 1 NC_011353.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 3203441 truA 6970479 truA Escherichia coli O157:H7 str. EC4115 tRNA pseudouridine synthase A YP_002271727.1 3202629 R 444450 CDS YP_002271728.1 209397868 6968237 complement(3203441..3204454) 1 NC_011353.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774; semialdehyde dehydrogenase 3204454 6968237 ECH74115_3459 Escherichia coli O157:H7 str. EC4115 semialdehyde dehydrogenase YP_002271728.1 3203441 R 444450 CDS YP_002271729.1 209395720 6968860 3204435..3204548 1 NC_011353.1 identified by glimmer; hypothetical protein 3204548 6968860 ECH74115_3461 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271729.1 3204435 D 444450 CDS YP_002271730.1 209395784 6966575 complement(3204520..3205656) 1 NC_011353.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; erythronate-4-phosphate dehydrogenase 3205656 pdxB 6966575 pdxB Escherichia coli O157:H7 str. EC4115 erythronate-4-phosphate dehydrogenase YP_002271730.1 3204520 R 444450 CDS YP_002271731.1 209400878 6966640 3205755..3206750 1 NC_011353.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 3206750 flk 6966640 flk Escherichia coli O157:H7 str. EC4115 flagella biosynthesis regulator YP_002271731.1 3205755 D 444450 CDS YP_002271732.1 209400286 6972110 complement(3206747..3207925) 1 NC_011353.1 identified by match to protein family HMM PF07690; hypothetical protein 3207925 6972110 ECH74115_3462 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271732.1 3206747 R 444450 CDS YP_002271733.1 209399153 6971480 complement(3208200..3209420) 1 NC_011353.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 3209420 fabB 6971480 fabB Escherichia coli O157:H7 str. EC4115 3-oxoacyl-ACP synthase YP_002271733.1 3208200 R 444450 CDS YP_002271734.1 209398413 6970260 3209579..3211585 1 NC_011353.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 3211585 mnmC 6970260 mnmC Escherichia coli O157:H7 str. EC4115 5-methylaminomethyl-2-thiouridine methyltransferase YP_002271734.1 3209579 D 444450 CDS YP_002271735.1 209398009 6969460 complement(3211706..3211984) 1 NC_011353.1 identified by match to protein family HMM PF08891; hypothetical protein 3211984 6969460 ECH74115_3466 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271735.1 3211706 R 444450 CDS YP_002271736.1 209396604 6969021 complement(3212018..3212566) 1 NC_011353.1 identified by match to protein family HMM PF04315; hypothetical protein 3212566 6969021 ECH74115_3467 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271736.1 3212018 R 444450 CDS YP_002271737.1 209396809 6967521 complement(3212566..3213375) 1 NC_011353.1 identified by match to protein family HMM PF01925; hypothetical protein 3213375 6967521 ECH74115_3468 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271737.1 3212566 R 444450 CDS YP_002271738.1 209396074 6967741 complement(3213375..3214199) 1 NC_011353.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 3214199 mepA 6967741 mepA Escherichia coli O157:H7 str. EC4115 penicillin-insensitive murein endopeptidase YP_002271738.1 3213375 R 444450 CDS YP_002271739.1 209400995 6966953 complement(3214203..3215288) 1 NC_011353.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3215288 aroC 6966953 aroC Escherichia coli O157:H7 str. EC4115 chorismate synthase YP_002271739.1 3214203 R 444450 CDS YP_002271740.1 209400438 6972237 complement(3215323..3216255) 1 NC_011353.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 3216255 prmB 6972237 prmB Escherichia coli O157:H7 str. EC4115 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002271740.1 3215323 R 444450 CDS YP_002271741.1 209399827 6971640 3216421..3216972 1 NC_011353.1 identified by match to protein family HMM PF01713; hypothetical protein 3216972 6971640 ECH74115_3472 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271741.1 3216421 D 444450 CDS YP_002271742.1 209399052 6970984 complement(3217143..3217985) 1 NC_011353.1 hypothetical protein 3217985 6970984 ECH74115_3473 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271742.1 3217143 R 444450 CDS YP_002271743.1 209398508 6970154 complement(3217987..3218508) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 3218508 6970154 ECH74115_3474 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002271743.1 3217987 R 444450 CDS YP_002271744.1 209399360 6969566 complement(3218741..3218914) 1 NC_011353.1 minor fimbrial subunit 3218914 6969566 ECH74115_3475 Escherichia coli O157:H7 str. EC4115 minor fimbrial subunit YP_002271744.1 3218741 R 444450 CDS YP_002271745.1 209397626 6970482 complement(3218911..3219360) 1 NC_011353.1 fimbrial subunit 3219360 6970482 ECH74115_3476 Escherichia coli O157:H7 str. EC4115 fimbrial subunit YP_002271745.1 3218911 R 444450 CDS YP_002271746.1 209398183 6968608 complement(3219378..3219644) 1 NC_011353.1 fimbrial protein 3219644 6968608 ECH74115_3477 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002271746.1 3219378 R 444450 CDS YP_002271747.1 209397743 6969209 3219712..3219867 1 NC_011353.1 identified by glimmer; hypothetical protein 3219867 6969209 ECH74115_3478 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271747.1 3219712 D 444450 CDS YP_002271748.1 209395716 6968728 complement(3219889..3220647) 1 NC_011353.1 identified by match to protein family HMM PF00345; chaperone protein PapD 3220647 6968728 ECH74115_3479 Escherichia coli O157:H7 str. EC4115 chaperone protein PapD YP_002271748.1 3219889 R 444450 CDS YP_002271749.1 209396561 6966571 complement(3220670..3223252) 1 NC_011353.1 identified by match to protein family HMM PF00577; fimbrial usher protein 3223252 6966571 ECH74115_3480 Escherichia coli O157:H7 str. EC4115 fimbrial usher protein YP_002271749.1 3220670 R 444450 CDS YP_002271750.1 209398661 6967475 complement(3223391..3223954) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 3223954 6967475 ECH74115_3481 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002271750.1 3223391 R 444450 CDS YP_002271751.1 209399221 6969731 complement(3224600..3225085) 1 NC_011353.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249; phosphohistidine phosphatase 3225085 sixA 6969731 sixA Escherichia coli O157:H7 str. EC4115 phosphohistidine phosphatase YP_002271751.1 3224600 R 444450 CDS YP_002271752.1 209397393 6970331 3225062..3225214 1 NC_011353.1 identified by glimmer; hypothetical protein 3225214 6970331 ECH74115_3483 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271752.1 3225062 D 444450 CDS YP_002271753.1 209400826 6968359 complement(3225288..3227432) 1 NC_011353.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 3227432 fadJ 6968359 fadJ Escherichia coli O157:H7 str. EC4115 multifunctional fatty acid oxidation complex subunit alpha YP_002271753.1 3225288 R 444450 CDS YP_002271754.1 209400421 6972054 complement(3227432..3228742) 1 NC_011353.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 3228742 fadI 6972054 fadI Escherichia coli O157:H7 str. EC4115 3-ketoacyl-CoA thiolase YP_002271754.1 3227432 R 444450 CDS YP_002271755.1 209395983 6971623 complement(3228922..3229206) 1 NC_011353.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein 3229206 6971623 ECH74115_3486 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271755.1 3228922 R 444450 CDS YP_002271756.1 209397641 6966853 3229578..3230918 1 NC_011353.1 identified by match to protein family HMM PF03349; long-chain fatty acid outer membrane transporter 3230918 6966853 ECH74115_3487 Escherichia coli O157:H7 str. EC4115 long-chain fatty acid outer membrane transporter YP_002271756.1 3229578 D 444450 CDS YP_002271757.1 209398492 6969145 3232388..3232504 1 NC_011353.1 identified by glimmer; hypothetical protein 3232504 6969145 ECH74115_3489 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271757.1 3232388 D 444450 CDS YP_002271758.1 209399616 6969549 complement(3232709..3233464) 1 NC_011353.1 identified by match to protein family HMM PF04333; lipoprotein, VacJ family 3233464 6969549 ECH74115_3490 Escherichia coli O157:H7 str. EC4115 lipoprotein, VacJ family YP_002271758.1 3232709 R 444450 CDS YP_002271759.1 209399081 6969527 3233758..3234690 1 NC_011353.1 hypothetical protein 3234690 6969527 ECH74115_3492 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271759.1 3233758 D 444450 CDS YP_002271760.1 209399901 6971038 complement(3243356..3244621) 1 NC_011353.1 hypothetical protein 3244621 6971038 ECH74115_3494 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271760.1 3243356 R 444450 CDS YP_002271761.1 209397940 6971064 complement(3244632..3244925) 1 NC_011353.1 hypothetical protein 3244925 6971064 ECH74115_3495 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271761.1 3244632 R 444450 CDS YP_002271762.1 209398377 6968943 complement(3244935..3245381) 1 NC_011353.1 hypothetical protein 3245381 6968943 ECH74115_3496 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271762.1 3244935 R 444450 CDS YP_002271763.1 209397675 6969420 complement(3245384..3246040) 1 NC_011353.1 hypothetical protein 3246040 6969420 ECH74115_3497 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271763.1 3245384 R 444450 CDS YP_002271764.1 209398229 6968658 complement(3246135..3246512) 1 NC_011353.1 hypothetical protein 3246512 6968658 ECH74115_3498 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271764.1 3246135 R 444450 CDS YP_002271765.1 209396132 6969260 complement(3246593..3246733) 1 NC_011353.1 hypothetical protein 3246733 6969260 ECH74115_3499 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271765.1 3246593 R 444450 CDS YP_002271766.1 209396697 6967015 complement(3246964..3247698) 1 NC_011353.1 identified by match to protein family HMM PF06316; outer membrane protein Lom 3247698 6967015 ECH74115_3500 Escherichia coli O157:H7 str. EC4115 outer membrane protein Lom YP_002271766.1 3246964 R 444450 CDS YP_002271767.1 209400699 6971300 complement(3248412..3248690) 1 NC_011353.1 outer membrane protein 3248690 6971300 ECH74115_3502 Escherichia coli O157:H7 str. EC4115 outer membrane protein YP_002271767.1 3248412 R 444450 CDS YP_002271768.1 209400413 6971922 complement(3248705..3249919) 1 NC_011353.1 hypothetical protein 3249919 6971922 ECH74115_3503 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271768.1 3248705 R 444450 CDS YP_002271769.1 209400018 6971614 complement(3249970..3251595) 1 NC_011353.1 hypothetical protein 3251595 6971614 ECH74115_3504 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271769.1 3249970 R 444450 CDS YP_002271770.1 209398158 6971193 complement(3251710..3251823) 1 NC_011353.1 identified by glimmer; hypothetical protein 3251823 6971193 ECH74115_3505 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271770.1 3251710 R 444450 CDS YP_002271771.1 209396365 6969622 complement(3252217..3252486) 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 3252486 6969622 ECH74115_3507 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002271771.1 3252217 R 444450 CDS YP_002271772.1 209398916 6967267 complement(3252488..3254425) 1 NC_011353.1 identified by match to protein family HMM PF01391; match to protein family HMM PF03406; match to protein family HMM PF06820; match to protein family HMM PF08400; tail fiber protein 3254425 6967267 ECH74115_3508 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002271772.1 3252488 R 444450 CDS YP_002271773.1 209397163 6970008 complement(3254422..3255072) 1 NC_011353.1 hypothetical protein 3255072 6970008 ECH74115_3509 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271773.1 3254422 R 444450 CDS YP_002271774.1 209397704 6968116 complement(3255072..3255635) 1 NC_011353.1 hypothetical protein 3255635 6968116 ECH74115_3510 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271774.1 3255072 R 444450 CDS YP_002271775.1 209395749 6968688 complement(3255619..3256080) 1 NC_011353.1 hypothetical protein 3256080 6968688 ECH74115_3511 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271775.1 3255619 R 444450 CDS YP_002271776.1 209396476 6966604 complement(3256130..3256519) 1 NC_011353.1 hypothetical protein 3256519 6966604 ECH74115_3512 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271776.1 3256130 R 444450 CDS YP_002271777.1 209400284 6967387 complement(3256575..3257789) 1 NC_011353.1 hypothetical protein 3257789 6967387 ECH74115_3513 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271777.1 3256575 R 444450 CDS YP_002271778.1 209400517 6971478 complement(3257813..3258229) 1 NC_011353.1 hypothetical protein 3258229 6971478 ECH74115_3514 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271778.1 3257813 R 444450 CDS YP_002271779.1 209399958 6971724 3258360..3258686 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 3258686 6971724 ECH74115_3515 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002271779.1 3258360 D 444450 CDS YP_002271780.1 209399045 6971127 3258683..3259573 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 3259573 6971127 ECH74115_3516 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002271780.1 3258683 D 444450 CDS YP_002271781.1 209398460 6970147 complement(3259576..3260133) 1 NC_011353.1 hypothetical protein 3260133 6970147 ECH74115_3517 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271781.1 3259576 R 444450 CDS YP_002271782.1 209398286 6969513 complement(3260291..3262435) 1 NC_011353.1 identified by glimmer; hypothetical protein 3262435 6969513 ECH74115_3518 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271782.1 3260291 R 444450 CDS YP_002271783.1 209397398 6969320 complement(3262435..3264141) 1 NC_011353.1 large subunit terminase 3264141 6969320 ECH74115_3519 Escherichia coli O157:H7 str. EC4115 large subunit terminase YP_002271783.1 3262435 R 444450 CDS YP_002271784.1 209396435 6968364 complement(3264122..3264928) 1 NC_011353.1 hypothetical protein 3264928 6968364 ECH74115_3520 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271784.1 3264122 R 444450 CDS YP_002271785.1 209400316 6967344 complement(3264984..3265097) 1 NC_011353.1 hypothetical protein 3265097 6967344 ECH74115_3521 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271785.1 3264984 R 444450 CDS YP_002271786.1 209399732 6971512 3265337..3265630 1 NC_011353.1 identified by match to protein family HMM PF06291; Bor protein 3265630 6971512 ECH74115_3522 Escherichia coli O157:H7 str. EC4115 Bor protein YP_002271786.1 3265337 D 444450 CDS YP_002271787.1 209400794 6970885 complement(3265662..3266126) 1 NC_011353.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 3266126 6970885 ECH74115_3523 Escherichia coli O157:H7 str. EC4115 bacteriophage lysis protein YP_002271787.1 3265662 R 444450 CDS YP_002271788.1 209400311 6972021 complement(3266134..3266268) 1 NC_011353.1 hypothetical protein 3266268 6972021 ECH74115_3524 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271788.1 3266134 R 444450 CDS YP_002271789.1 209399563 6971506 complement(3266283..3266852) 1 NC_011353.1 anti-repressor protein Ant 3266852 6971506 ECH74115_3525 Escherichia coli O157:H7 str. EC4115 anti-repressor protein Ant YP_002271789.1 3266283 R 444450 CDS YP_002271790.1 209397830 6970701 complement(3267126..3267659) 1 NC_011353.1 identified by match to protein family HMM PF00959; lysozyme 3267659 6970701 ECH74115_3526 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002271790.1 3267126 R 444450 CDS YP_002271791.1 209397048 6968821 complement(3267664..3267879) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 3267879 6968821 ECH74115_3527 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271791.1 3267664 R 444450 CDS YP_002271792.1 209396352 6967994 complement(3267956..3268228) 1 NC_011353.1 identified by match to protein family HMM PF05696; hypothetical protein 3268228 6967994 ECH74115_3528 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271792.1 3267956 R 444450 CDS YP_002271793.1 209395941 6967254 complement(3268269..3268448) 1 NC_011353.1 identified by match to protein family HMM PF07125; hypothetical protein 3268448 6967254 ECH74115_3529 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271793.1 3268269 R 444450 CDS YP_002271794.1 209400504 6966808 complement(3268461..3268586) 1 NC_011353.1 hypothetical protein 3268586 6966808 ECH74115_3530 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271794.1 3268461 R 444450 CDS YP_002271795.1 209398813 6971709 complement(3268583..3270520) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 3270520 6971709 ECH74115_3531 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271795.1 3268583 R 444450 CDS YP_002271796.1 209397197 6969893 complement(3271007..3271276) 1 NC_011353.1 identified by match to protein family HMM PF02258; shiga toxin 2 B subunit 3271276 6969893 ECH74115_3532 Escherichia coli O157:H7 str. EC4115 shiga toxin 2 B subunit YP_002271796.1 3271007 R 444450 CDS YP_002271797.1 209396141 6968153 complement(3271288..3272247) 1 NC_011353.1 identified by match to protein family HMM PF00161; shiga toxin subunit A 3272247 6968153 ECH74115_3533 Escherichia coli O157:H7 str. EC4115 shiga toxin subunit A YP_002271797.1 3271288 R 444450 CDS YP_002271798.1 209397666 6967616 complement(3273029..3273220) 1 NC_011353.1 antitermination protein 3273220 6967616 ECH74115_3538 Escherichia coli O157:H7 str. EC4115 antitermination protein YP_002271798.1 3273029 R 444450 CDS YP_002271799.1 209398224 6968649 3273200..3273343 1 NC_011353.1 identified by glimmer; hypothetical protein 3273343 6968649 ECH74115_3539 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271799.1 3273200 D 444450 CDS YP_002271800.1 209397779 6969253 complement(3273456..3273650) 1 NC_011353.1 identified by match to protein family HMM PF06322; hypothetical protein 3273650 6969253 ECH74115_3540 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271800.1 3273456 R 444450 CDS YP_002271801.1 209398365 6968767 complement(3273647..3274252) 1 NC_011353.1 identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein 3274252 6968767 ECH74115_3541 Escherichia coli O157:H7 str. EC4115 bacteriophage Lambda NinG protein YP_002271801.1 3273647 R 444450 CDS YP_002271802.1 209399228 6969408 complement(3274252..3274974) 1 NC_011353.1 identified by match to protein family HMM PF03374; DNA-binding protein Roi 3274974 6969408 ECH74115_3542 Escherichia coli O157:H7 str. EC4115 DNA-binding protein Roi YP_002271802.1 3274252 R 444450 CDS YP_002271803.1 209399751 6970339 complement(3275136..3275537) 1 NC_011353.1 hypothetical protein 3275537 6970339 ECH74115_3543 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271803.1 3275136 R 444450 CDS YP_002271804.1 209398856 6970907 complement(3275612..3276286) 1 NC_011353.1 hypothetical protein 3276286 6970907 ECH74115_3544 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271804.1 3275612 R 444450 CDS YP_002271805.1 209398261 6969941 complement(3276734..3277261) 1 NC_011353.1 identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712; phage N-6-adenine-methyltransferase 3277261 6969941 ECH74115_3545 Escherichia coli O157:H7 str. EC4115 phage N-6-adenine-methyltransferase YP_002271805.1 3276734 R 444450 CDS YP_002271806.1 209397029 6969293 complement(3277287..3277406) 1 NC_011353.1 identified by glimmer; hypothetical protein 3277406 6969293 ECH74115_3546 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271806.1 3277287 R 444450 CDS YP_002271807.1 209397839 6967973 3278135..3278248 1 NC_011353.1 identified by glimmer; hypothetical protein 3278248 6967973 ECH74115_3547 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271807.1 3278135 D 444450 CDS YP_002271808.1 209398200 6968831 complement(3278250..3278432) 1 NC_011353.1 hypothetical protein 3278432 6968831 ECH74115_3548 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271808.1 3278250 R 444450 CDS YP_002271809.1 209399346 6970062 complement(3278791..3279069) 1 NC_011353.1 hypothetical protein 3279069 6970062 ECH74115_3550 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271809.1 3278791 R 444450 CDS YP_002271810.1 209400117 6970467 complement(3279140..3279430) 1 NC_011353.1 Ren protein 3279430 6970467 ECH74115_3551 Escherichia coli O157:H7 str. EC4115 Ren protein YP_002271810.1 3279140 R 444450 CDS YP_002271811.1 209400536 6971301 complement(3279427..3280128) 1 NC_011353.1 identified by match to protein family HMM PF06992; replication protein P 3280128 6971301 ECH74115_3552 Escherichia coli O157:H7 str. EC4115 replication protein P YP_002271811.1 3279427 R 444450 CDS YP_002271812.1 209395860 6971743 complement(3280125..3281063) 1 NC_011353.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610; replication protein O 3281063 6971743 ECH74115_3553 Escherichia coli O157:H7 str. EC4115 replication protein O YP_002271812.1 3280125 R 444450 CDS YP_002271813.1 209397685 6966719 complement(3281096..3281392) 1 NC_011353.1 identified by match to protein family HMM PF05269; bacteriophage CII protein 3281392 6966719 ECH74115_3554 Escherichia coli O157:H7 str. EC4115 bacteriophage CII protein YP_002271813.1 3281096 R 444450 CDS YP_002271814.1 209398566 6968668 complement(3281531..3281758) 1 NC_011353.1 hypothetical protein 3281758 6968668 ECH74115_3555 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271814.1 3281531 R 444450 CDS YP_002271815.1 209398778 6969627 3281837..3282544 1 NC_011353.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381; repressor protein CI 3282544 6969627 ECH74115_3556 Escherichia coli O157:H7 str. EC4115 repressor protein CI YP_002271815.1 3281837 D 444450 CDS YP_002271816.1 209399340 6969856 3282605..3282946 1 NC_011353.1 hypothetical protein 3282946 6969856 ECH74115_3557 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271816.1 3282605 D 444450 CDS YP_002271817.1 209400243 6970460 3283469..3284515 1 NC_011353.1 identified by match to protein family HMM PF00069; serine/threonine kinase 3284515 6970460 ECH74115_3558 Escherichia coli O157:H7 str. EC4115 serine/threonine kinase YP_002271817.1 3283469 D 444450 CDS YP_002271818.1 209398470 6971434 3285171..3285554 1 NC_011353.1 antitermination protein N 3285554 6971434 ECH74115_3559 Escherichia coli O157:H7 str. EC4115 antitermination protein N YP_002271818.1 3285171 D 444450 CDS YP_002271819.1 209395844 6969525 3285613..3286083 1 NC_011353.1 identified by glimmer; hypothetical protein 3286083 6969525 ECH74115_3560 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271819.1 3285613 D 444450 CDS YP_002271820.1 209396410 6966701 3286234..3286602 1 NC_011353.1 identified by glimmer; hypothetical protein 3286602 6966701 ECH74115_3561 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271820.1 3286234 D 444450 CDS YP_002271821.1 209397323 6967317 3286808..3286972 1 NC_011353.1 lambda Kil 3286972 6967317 ECH74115_3562 Escherichia coli O157:H7 str. EC4115 lambda Kil YP_002271821.1 3286808 D 444450 CDS YP_002271822.1 209397873 6968286 3287027..3287323 1 NC_011353.1 identified by match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 3287323 gam 6968286 gam Escherichia coli O157:H7 str. EC4115 host-nuclease inhibitor protein Gam YP_002271822.1 3287027 D 444450 CDS YP_002271823.1 209399367 6968868 3287329..3288114 1 NC_011353.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 3288114 bet 6968868 bet Escherichia coli O157:H7 str. EC4115 phage recombination protein Bet YP_002271823.1 3287329 D 444450 CDS YP_002271824.1 209397437 6970491 3288111..3288791 1 NC_011353.1 identified by match to protein family HMM PF09588; exonuclease 3288791 exo 6970491 exo Escherichia coli O157:H7 str. EC4115 exonuclease YP_002271824.1 3288111 D 444450 CDS YP_002271825.1 209399106 6968406 3289021..3289134 1 NC_011353.1 hypothetical protein 3289134 6968406 ECH74115_3566 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271825.1 3289021 D 444450 CDS YP_002271826.1 209399764 6970208 3289211..3289426 1 NC_011353.1 hypothetical protein 3289426 6970208 ECH74115_3567 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271826.1 3289211 D 444450 CDS YP_002271827.1 209396340 6970920 3289743..3290690 1 NC_011353.1 identified by match to protein family HMM PF04447; hypothetical protein 3290690 6970920 ECH74115_3568 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271827.1 3289743 D 444450 CDS YP_002271828.1 209396904 6967241 3290692..3291198 1 NC_011353.1 bacteriophage protein 3291198 6967241 ECH74115_3569 Escherichia coli O157:H7 str. EC4115 bacteriophage protein YP_002271828.1 3290692 D 444450 CDS YP_002271829.1 209397485 6967842 3291158..3291373 1 NC_011353.1 hypothetical protein 3291373 6967842 ECH74115_3570 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271829.1 3291158 D 444450 CDS YP_002271830.1 209398047 6968456 3291375..3291593 1 NC_011353.1 hypothetical protein 3291593 6968456 ECH74115_3571 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271830.1 3291375 D 444450 CDS YP_002271831.1 209399423 6969061 3291595..3291882 1 NC_011353.1 hypothetical protein 3291882 6969061 ECH74115_3572 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271831.1 3291595 D 444450 CDS YP_002271832.1 209398630 6969896 3293113..3293766 1 NC_011353.1 identified by match to protein family HMM PF08346; phage anti-repressor protein AntB 3293766 6969896 ECH74115_3574 Escherichia coli O157:H7 str. EC4115 phage anti-repressor protein AntB YP_002271832.1 3293113 D 444450 CDS YP_002271833.1 209399242 6969694 3293809..3293976 1 NC_011353.1 hypothetical protein 3293976 6969694 ECH74115_3575 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271833.1 3293809 D 444450 CDS YP_002271834.1 209400932 6970354 3294203..3294829 1 NC_011353.1 identified by match to protein family HMM PF05063; adenine methylase 3294829 6970354 ECH74115_3576 Escherichia coli O157:H7 str. EC4115 adenine methylase YP_002271834.1 3294203 D 444450 CDS YP_002271835.1 209399670 6972169 3294789..3295001 1 NC_011353.1 hypothetical protein 3295001 6972169 ECH74115_3577 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271835.1 3294789 D 444450 CDS YP_002271836.1 209399502 6970817 3295037..3295414 1 NC_011353.1 hypothetical protein 3295414 6970817 ECH74115_3578 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271836.1 3295037 D 444450 CDS YP_002271837.1 209397899 6970637 3295493..3295675 1 NC_011353.1 hypothetical protein 3295675 6970637 ECH74115_3580 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271837.1 3295493 D 444450 CDS YP_002271838.1 209400578 6968897 complement(3295659..3296828) 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase 3296828 6968897 ECH74115_3579 Escherichia coli O157:H7 str. EC4115 integrase YP_002271838.1 3295659 R 444450 CDS YP_002271839.1 209397288 6972415 3297224..3298417 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase 3298417 6972415 ECH74115_3582 Escherichia coli O157:H7 str. EC4115 integrase YP_002271839.1 3297224 D 444450 CDS YP_002271840.1 209396377 6968249 complement(3298592..3299728) 1 NC_011353.1 DNA injection protein 3299728 6968249 ECH74115_3583 Escherichia coli O157:H7 str. EC4115 DNA injection protein YP_002271840.1 3298592 R 444450 CDS YP_002271841.1 209395838 6967282 complement(3299738..3300364) 1 NC_011353.1 DNA transfer protein 3300364 6967282 ECH74115_3584 Escherichia coli O157:H7 str. EC4115 DNA transfer protein YP_002271841.1 3299738 R 444450 CDS YP_002271842.1 209400252 6966695 complement(3300405..3300872) 1 NC_011353.1 hypothetical protein 3300872 6966695 ECH74115_3585 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271842.1 3300405 R 444450 CDS YP_002271843.1 209396795 6971443 complement(3300872..3301402) 1 NC_011353.1 hypothetical protein 3301402 6971443 ECH74115_3586 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271843.1 3300872 R 444450 CDS YP_002271844.1 209397956 6967727 3301424..3302119 1 NC_011353.1 replication protein 3302119 6967727 ECH74115_3587 Escherichia coli O157:H7 str. EC4115 replication protein YP_002271844.1 3301424 D 444450 CDS YP_002271845.1 209396042 6968961 complement(3302789..3304201) 1 NC_011353.1 hypothetical protein 3304201 6968961 ECH74115_3588 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271845.1 3302789 R 444450 CDS YP_002271846.1 209399468 6966918 complement(3304388..3304564) 1 NC_011353.1 hypothetical protein 3304564 6966918 ECH74115_3589 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271846.1 3304388 R 444450 CDS YP_002271847.1 209397434 6970600 3304867..3305493 1 NC_011353.1 resolvase domain-containing protein 3305493 6970600 ECH74115_3590 Escherichia coli O157:H7 str. EC4115 resolvase domain-containing protein YP_002271847.1 3304867 D 444450 CDS YP_002271848.1 209400885 6971474 complement(3307410..3308324) 1 NC_011353.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 3308324 cscK 6971474 cscK Escherichia coli O157:H7 str. EC4115 aminoimidazole riboside kinase YP_002271848.1 3307410 R 444450 CDS YP_002271849.1 209397537 6972118 complement(3308415..3308576) 1 NC_011353.1 identified by glimmer; hypothetical protein 3308576 6972118 ECH74115_3593 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271849.1 3308415 R 444450 CDS YP_002271850.1 209399695 6968510 3308531..3309973 1 NC_011353.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 3309973 6968510 ECH74115_3594 Escherichia coli O157:H7 str. EC4115 sucrose-6-phosphate hydrolase YP_002271850.1 3308531 D 444450 CDS YP_002271851.1 209396088 6970845 complement(3309981..3310976) 1 NC_011353.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar binding transcriptional regulator, LacI family 3310976 6970845 ECH74115_3595 Escherichia coli O157:H7 str. EC4115 sugar binding transcriptional regulator, LacI family YP_002271851.1 3309981 R 444450 CDS YP_002271852.1 209396658 6966967 3311219..3311437 1 NC_011353.1 identified by glimmer; hypothetical protein 3311437 6966967 ECH74115_3596 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271852.1 3311219 D 444450 CDS YP_002271853.1 209396399 6967579 3311455..3312783 1 NC_011353.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 3312783 dsdA 6967579 dsdA Escherichia coli O157:H7 str. EC4115 D-serine dehydratase YP_002271853.1 3311455 D 444450 CDS YP_002271854.1 209400997 6967306 complement(3312891..3314429) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; multidrug resistance protein Y 3314429 emrY 6967306 emrY Escherichia coli O157:H7 str. EC4115 multidrug resistance protein Y YP_002271854.1 3312891 R 444450 CDS YP_002271855.1 209397981 6972239 complement(3314429..3315592) 1 NC_011353.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998; drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK 3315592 emrK 6972239 emrK Escherichia coli O157:H7 str. EC4115 drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK YP_002271855.1 3314429 R 444450 CDS YP_002271856.1 209397221 6968992 3316008..3316622 1 NC_011353.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 3316622 evgA 6968992 evgA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator EvgA YP_002271856.1 3316008 D 444450 CDS YP_002271857.1 209399540 6968179 3316837..3320220 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518; hybrid sensory histidine kinase in two-component regulatory system with EvgA 3320220 evgS 6968179 evgS Escherichia coli O157:H7 str. EC4115 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_002271857.1 3316837 D 444450 CDS YP_002271858.1 209400136 6971844 complement(3321491..3322435) 1 NC_011353.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 3322435 6971844 ECH74115_3604 Escherichia coli O157:H7 str. EC4115 transporter YfdV YP_002271858.1 3321491 R 444450 CDS YP_002271859.1 209399559 6971322 complement(3322505..3324199) 1 NC_011353.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 3324199 oxc 6971322 oxc Escherichia coli O157:H7 str. EC4115 oxalyl-CoA decarboxylase YP_002271859.1 3322505 R 444450 CDS YP_002271860.1 209398990 6970697 complement(3324253..3325503) 1 NC_011353.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 3325503 frc 6970697 frc Escherichia coli O157:H7 str. EC4115 formyl-coenzyme A transferase YP_002271860.1 3324253 R 444450 CDS YP_002271861.1 209398038 6970089 complement(3326016..3326651) 1 NC_011353.1 hypothetical protein 3326651 6970089 ECH74115_3607 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271861.1 3326016 R 444450 CDS YP_002271862.1 209397382 6969051 complement(3327299..3327541) 1 NC_011353.1 hypothetical protein 3327541 6969051 ECH74115_3608 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271862.1 3327299 R 444450 CDS YP_002271863.1 209398439 6968348 3327894..3328814 1 NC_011353.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 3328814 6968348 ECH74115_3609 Escherichia coli O157:H7 str. EC4115 lipid A biosynthesis palmitoleoyl acyltransferase YP_002271863.1 3327894 D 444450 CDS YP_002271864.1 209397882 6969491 3329125..3329241 1 NC_011353.1 identified by glimmer; hypothetical protein 3329241 6969491 ECH74115_3610 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271864.1 3329125 D 444450 CDS YP_002271865.1 209400401 6968879 complement(3329306..3330544) 1 NC_011353.1 identified by match to protein family HMM PF00155; aminotransferase 3330544 6968879 ECH74115_3611 Escherichia coli O157:H7 str. EC4115 aminotransferase YP_002271865.1 3329306 R 444450 CDS YP_002271866.1 209399684 6971602 3330939..3332618 1 NC_011353.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 3332618 6971602 ECH74115_3612 Escherichia coli O157:H7 str. EC4115 sensor histidine kinase YP_002271866.1 3330939 D 444450 CDS YP_002271867.1 209396875 6970833 3332633..3333367 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 3333367 6970833 ECH74115_3613 Escherichia coli O157:H7 str. EC4115 response regulator YP_002271867.1 3332633 D 444450 CDS YP_002271868.1 209396146 6967812 3333380..3334237 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3334237 6967812 ECH74115_3614 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002271868.1 3333380 D 444450 CDS YP_002271869.1 209396468 6967029 complement(3334240..3336735) 1 NC_011353.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417; multiphosphoryl transfer protein 1 3336735 fryA 6967029 fryA Escherichia coli O157:H7 str. EC4115 multiphosphoryl transfer protein 1 YP_002271869.1 3334240 R 444450 CDS YP_002271870.1 209395774 6967379 complement(3336760..3337797) 1 NC_011353.1 metalloprotein; exoaminopeptidase 3337797 6967379 ECH74115_3616 Escherichia coli O157:H7 str. EC4115 exoaminopeptidase YP_002271870.1 3336760 R 444450 CDS YP_002271871.1 209397138 6966630 complement(3337797..3338882) 1 NC_011353.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 3338882 ypdF 6966630 ypdF Escherichia coli O157:H7 str. EC4115 aminopeptidase YP_002271871.1 3337797 R 444450 CDS YP_002271872.1 209396535 6968089 complement(3338897..3340144) 1 NC_011353.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system fructose-like transporter subunit IIC 3340144 fryC 6968089 fryC Escherichia coli O157:H7 str. EC4115 PTS system fructose-like transporter subunit IIC YP_002271872.1 3338897 R 444450 CDS YP_002271873.1 209395945 6967448 complement(3340166..3340492) 1 NC_011353.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829; PTS system fructose specific transporter subunit IIB 3340492 6967448 ECH74115_3619 Escherichia coli O157:H7 str. EC4115 PTS system fructose specific transporter subunit IIB YP_002271873.1 3340166 R 444450 CDS YP_002271874.1 209397745 6966812 complement(3340711..3341676) 1 NC_011353.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 3341676 glk 6966812 glk Escherichia coli O157:H7 str. EC4115 glucokinase YP_002271874.1 3340711 R 444450 CDS YP_002271875.1 209397098 6968730 3341880..3343136 1 NC_011353.1 identified by match to protein family HMM PF00654; hypothetical protein 3343136 6968730 ECH74115_3621 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271875.1 3341880 D 444450 CDS YP_002271876.1 209399524 6968046 3343251..3343577 1 NC_011353.1 hypothetical protein 3343577 6968046 ECH74115_3622 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271876.1 3343251 D 444450 CDS YP_002271877.1 209399083 6970660 complement(3343717..3344955) 1 NC_011353.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 3344955 mntH 6970660 mntH Escherichia coli O157:H7 str. EC4115 manganese transport protein MntH YP_002271877.1 3343717 R 444450 CDS YP_002271878.1 209400703 6970185 3345291..3346493 1 NC_011353.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC 3346493 nupC 6970185 nupC Escherichia coli O157:H7 str. EC4115 nucleoside transporter NupC YP_002271878.1 3345291 D 444450 CDS YP_002271879.1 209400107 6971926 complement(3346543..3348732) 1 NC_011353.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231; diguanylate cyclase 3348732 6971926 ECH74115_3625 Escherichia coli O157:H7 str. EC4115 diguanylate cyclase YP_002271879.1 3346543 R 444450 CDS YP_002271880.1 209399965 6972359 3349366..3349710 1 NC_011353.1 identified by match to protein family HMM PF07037; hypothetical protein 3349710 6972359 ECH74115_3628 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271880.1 3349366 D 444450 CDS YP_002271881.1 209396351 6971135 3349712..3350104 1 NC_011353.1 identified by match to protein family HMM PF07037; hypothetical protein 3350104 6971135 ECH74115_3629 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271881.1 3349712 D 444450 CDS YP_002271882.1 209400602 6967253 complement(3350144..3351352) 1 NC_011353.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; transposase, IS605 orfB family 3351352 6967253 ECH74115_3630 Escherichia coli O157:H7 str. EC4115 transposase, IS605 orfB family YP_002271882.1 3350144 R 444450 CDS YP_002271883.1 209399878 6971813 3351375..3351902 1 NC_011353.1 identified by match to protein family HMM PF01797; transposase family protein 3351902 6971813 ECH74115_3631 Escherichia coli O157:H7 str. EC4115 transposase family protein YP_002271883.1 3351375 D 444450 CDS YP_002271884.1 209396142 6971039 complement(3351903..3353318) 1 NC_011353.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 3353318 gltX 6971039 gltX Escherichia coli O157:H7 str. EC4115 glutamyl-tRNA synthetase YP_002271884.1 3351903 R 444450 CDS YP_002271885.1 209400713 6967025 3353322..3353453 1 NC_011353.1 identified by glimmer; hypothetical protein 3353453 6967025 ECH74115_3633 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271885.1 3353322 D 444450 CDS YP_002271886.1 209396869 6972437 3354094..3354435 1 NC_011353.1 identified by glimmer; hypothetical protein 3354435 6972437 ECH74115_3639 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271886.1 3354094 D 444450 CDS YP_002271887.1 209397078 6967804 complement(3354426..3355352) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3355352 6967804 ECH74115_3638 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002271887.1 3354426 R 444450 CDS YP_002271888.1 209397693 6968024 3355442..3356440 1 NC_011353.1 identified by match to protein family HMM PF01758; sodium:bile acid symporter family protein 3356440 6968024 ECH74115_3641 Escherichia coli O157:H7 str. EC4115 sodium:bile acid symporter family protein YP_002271888.1 3355442 D 444450 CDS YP_002271889.1 209398574 6968676 complement(3356437..3356655) 1 NC_011353.1 hypothetical protein 3356655 6968676 ECH74115_3640 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271889.1 3356437 R 444450 CDS YP_002271890.1 209399429 6969635 complement(3356657..3358672) 1 NC_011353.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 3358672 ligA 6969635 ligA Escherichia coli O157:H7 str. EC4115 NAD-dependent DNA ligase LigA YP_002271890.1 3356657 R 444450 CDS YP_002271891.1 209400232 6970557 complement(3358743..3359741) 1 NC_011353.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 3359741 zipA 6970557 zipA Escherichia coli O157:H7 str. EC4115 cell division protein ZipA YP_002271891.1 3358743 R 444450 CDS YP_002271892.1 209397667 6971422 3359971..3360732 1 NC_011353.1 role in sulfur assimilation; sulfate transport protein CysZ 3360732 cysZ 6971422 cysZ Escherichia coli O157:H7 str. EC4115 sulfate transport protein CysZ YP_002271892.1 3359971 D 444450 CDS YP_002271893.1 209399427 6968650 3360917..3361888 1 NC_011353.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 3361888 cysK 6968650 cysK Escherichia coli O157:H7 str. EC4115 cysteine synthase A YP_002271893.1 3360917 D 444450 CDS YP_002271894.1 209398809 6970555 3362272..3362529 1 NC_011353.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 3362529 ptsH 6970555 ptsH Escherichia coli O157:H7 str. EC4115 PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_002271894.1 3362272 D 444450 CDS YP_002271895.1 209400537 6969889 3362574..3364301 1 NC_011353.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 3364301 ptsI 6969889 ptsI Escherichia coli O157:H7 str. EC4115 phosphoenolpyruvate-protein phosphotransferase YP_002271895.1 3362574 D 444450 CDS YP_002271896.1 209396526 6971744 3364342..3364851 1 NC_011353.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 3364851 crr 6971744 crr Escherichia coli O157:H7 str. EC4115 PTS system glucose-specific transporter YP_002271896.1 3364342 D 444450 CDS YP_002271897.1 209395957 6967439 complement(3364894..3365745) 1 NC_011353.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 3365745 pdxK 6967439 pdxK Escherichia coli O157:H7 str. EC4115 pyridoxal kinase YP_002271897.1 3364894 R 444450 CDS YP_002271898.1 209397165 6968733 complement(3366220..3367131) 1 NC_011353.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 3367131 cysM 6968733 cysM Escherichia coli O157:H7 str. EC4115 cysteine synthase B YP_002271898.1 3366220 R 444450 CDS YP_002271899.1 209398303 6968118 complement(3367265..3368362) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate/thiosulfate transporter subunit 3368362 cysA 6968118 cysA Escherichia coli O157:H7 str. EC4115 sulfate/thiosulfate transporter subunit YP_002271899.1 3367265 R 444450 CDS YP_002271900.1 209397225 6969339 complement(3368352..3369227) 1 NC_011353.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 3369227 cysW 6969339 cysW Escherichia coli O157:H7 str. EC4115 sulfate/thiosulfate transporter permease subunit YP_002271900.1 3368352 R 444450 CDS YP_002271901.1 209399387 6968183 complement(3369227..3370060) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate/thiosulfate transporter subunit 3370060 cysT 6968183 cysT Escherichia coli O157:H7 str. EC4115 sulfate/thiosulfate transporter subunit YP_002271901.1 3369227 R 444450 CDS YP_002271902.1 209398969 6970512 complement(3370060..3371076) 1 NC_011353.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; thiosulfate transporter subunit 3371076 cysP 6970512 cysP Escherichia coli O157:H7 str. EC4115 thiosulfate transporter subunit YP_002271902.1 3370060 R 444450 CDS YP_002271903.1 209397809 6970065 complement(3371234..3372025) 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; short chain dehydrogenase 3372025 ucpA 6970065 ucpA Escherichia coli O157:H7 str. EC4115 short chain dehydrogenase YP_002271903.1 3371234 R 444450 CDS YP_002271904.1 209397005 6968799 complement(3372154..3373011) 1 NC_011353.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 3373011 6968799 ECH74115_3657 Escherichia coli O157:H7 str. EC4115 RpiR family transcriptional regulator YP_002271904.1 3372154 R 444450 CDS YP_002271905.1 209397091 6967947 3373175..3374071 1 NC_011353.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 3374071 murQ 6967947 murQ Escherichia coli O157:H7 str. EC4115 N-acetylmuramic acid 6-phosphate etherase YP_002271905.1 3373175 D 444450 CDS YP_002271906.1 209396644 6968037 3374075..3375499 1 NC_011353.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 3375499 murP 6968037 murP Escherichia coli O157:H7 str. EC4115 PTS system N-acetylmuramic acid transporter subunit IIBC YP_002271906.1 3374075 D 444450 CDS YP_002271907.1 209395895 6967564 3375504..3376808 1 NC_011353.1 identified by match to protein family HMM PF00144; hypothetical protein 3376808 6967564 ECH74115_3660 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271907.1 3375504 D 444450 CDS YP_002271908.1 209400011 6966761 complement(3376866..3377765) 1 NC_011353.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413; dyp-type peroxidase family protein 3377765 6966761 ECH74115_3661 Escherichia coli O157:H7 str. EC4115 dyp-type peroxidase family protein YP_002271908.1 3376866 R 444450 CDS YP_002271909.1 209400074 6971186 complement(3377861..3378436) 1 NC_011353.1 identified by match to protein family HMM PF06572; hypothetical protein 3378436 6971186 ECH74115_3662 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271909.1 3377861 R 444450 CDS YP_002271910.1 209400882 6971253 complement(3378497..3378844) 1 NC_011353.1 inner membrane protein YfeZ 3378844 6971253 ECH74115_3663 Escherichia coli O157:H7 str. EC4115 inner membrane protein YfeZ YP_002271910.1 3378497 R 444450 CDS YP_002271911.1 209397042 6972114 complement(3378933..3379358) 1 NC_011353.1 identified by match to protein family HMM PF00583; acetyltransferase 3379358 6972114 ECH74115_3664 Escherichia coli O157:H7 str. EC4115 acetyltransferase YP_002271911.1 3378933 R 444450 CDS YP_002271912.1 209397820 6967987 3379572..3380441 1 NC_011353.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-l-alanine amidase I 3380441 amiA 6967987 amiA Escherichia coli O157:H7 str. EC4115 N-acetylmuramoyl-l-alanine amidase I YP_002271912.1 3379572 D 444450 CDS YP_002271913.1 209395878 6968811 3380445..3381344 1 NC_011353.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 3381344 hemF 6968811 hemF Escherichia coli O157:H7 str. EC4115 coproporphyrinogen III oxidase YP_002271913.1 3380445 D 444450 CDS YP_002271914.1 209396622 6966742 complement(3381350..3382402) 1 NC_011353.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 3382402 6966742 ECH74115_3667 Escherichia coli O157:H7 str. EC4115 transcriptional regulator EutR YP_002271914.1 3381350 R 444450 CDS YP_002271915.1 209396693 6967542 complement(3382448..3382948) 1 NC_011353.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutK 3382948 6967542 ECH74115_3668 Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutK YP_002271915.1 3382448 R 444450 CDS YP_002271916.1 209400275 6967615 complement(3382961..3383620) 1 NC_011353.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutL 3383620 6967615 ECH74115_3669 Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutL YP_002271916.1 3382961 R 444450 CDS YP_002271917.1 209400550 6971468 complement(3383630..3384517) 1 NC_011353.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 3384517 eutC 6971468 eutC Escherichia coli O157:H7 str. EC4115 ethanolamine ammonia-lyase small subunit YP_002271917.1 3383630 R 444450 CDS YP_002271918.1 209398786 6971759 complement(3384538..3385899) 1 NC_011353.1 identified by match to protein family HMM PF06751; ethanolamine ammonia-lyase, large subunit 3385899 eutB 6971759 eutB Escherichia coli O157:H7 str. EC4115 ethanolamine ammonia-lyase, large subunit YP_002271918.1 3384538 R 444450 CDS YP_002271919.1 209400026 6969864 complement(3385911..3387314) 1 NC_011353.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 3387314 eutA 6969864 eutA Escherichia coli O157:H7 str. EC4115 reactivating factor for ethanolamine ammonia lyase YP_002271919.1 3385911 R 444450 CDS YP_002271920.1 209400184 6971201 complement(3387311..3388537) 1 NC_011353.1 identified by match to protein family HMM PF04346; ethanolamine utilization protein EutH 3388537 eutH 6971201 eutH Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutH YP_002271920.1 3387311 R 444450 CDS YP_002271921.1 209395898 6971371 complement(3388637..3389824) 1 NC_011353.1 identified by match to protein family HMM PF00465; ethanolamine utilization protein EutG 3389824 eutG 6971371 eutG Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutG YP_002271921.1 3388637 R 444450 CDS YP_002271922.1 209397946 6966764 complement(3389814..3390650) 1 NC_011353.1 identified by match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ 3390650 eutJ 6966764 eutJ Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutJ YP_002271922.1 3389814 R 444450 CDS YP_002271923.1 209399410 6968949 complement(3390661..3392064) 1 NC_011353.1 identified by match to protein family HMM PF00171; ethanolamine utilization protein EutE 3392064 eutE 6968949 eutE Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutE YP_002271923.1 3390661 R 444450 CDS YP_002271924.1 209398821 6970536 complement(3392076..3392363) 1 NC_011353.1 identified by match to protein family HMM PF03319; ethanolamine utilization protein 3392363 eutN 6970536 eutN Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein YP_002271924.1 3392076 R 444450 CDS YP_002271925.1 209399009 6969904 complement(3392470..3392763) 1 NC_011353.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutM 3392763 eutM 6969904 eutM Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutM YP_002271925.1 3392470 R 444450 CDS YP_002271926.1 209400708 6970108 complement(3392802..3393818) 1 NC_011353.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 3393818 eutD 6970108 eutD Escherichia coli O157:H7 str. EC4115 phosphotransacetylase YP_002271926.1 3392802 R 444450 CDS YP_002271927.1 209399800 6971931 complement(3393815..3394546) 1 NC_011353.1 identified by match to protein family HMM PF01923; ethanolamine utilization cobalamin adenosyltransferase 3394546 6971931 ECH74115_3680 Escherichia coli O157:H7 str. EC4115 ethanolamine utilization cobalamin adenosyltransferase YP_002271927.1 3393815 R 444450 CDS YP_002271928.1 209396897 6970957 complement(3394543..3395244) 1 NC_011353.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249; ethanolamine utilization protein EutQ 3395244 eutQ 6970957 eutQ Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutQ YP_002271928.1 3394543 R 444450 CDS YP_002271929.1 209400396 6967835 complement(3395219..3395698) 1 NC_011353.1 identified by match to protein family HMM TIGR02528; ethanolamine utilization protein, EutP 3395698 eutP 6967835 eutP Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein, EutP YP_002271929.1 3395219 R 444450 CDS YP_002271930.1 209397456 6971597 complement(3395711..3396046) 1 NC_011353.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutS 3396046 6971597 ECH74115_3683 Escherichia coli O157:H7 str. EC4115 ethanolamine utilization protein EutS YP_002271930.1 3395711 R 444450 CDS YP_002271931.1 209398066 6968427 complement(3396339..3398618) 1 NC_011353.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 3398618 maeB 6968427 maeB Escherichia coli O157:H7 str. EC4115 malic enzyme YP_002271931.1 3396339 R 444450 CDS YP_002271932.1 209399196 6969083 3398907..3399857 1 NC_011353.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase A 3399857 tal1 6969083 tal1 Escherichia coli O157:H7 str. EC4115 transaldolase A YP_002271932.1 3398907 D 444450 CDS YP_002271933.1 209398617 6970304 3399877..3401880 1 NC_011353.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3401880 tktB 6970304 tktB Escherichia coli O157:H7 str. EC4115 transketolase YP_002271933.1 3399877 D 444450 CDS YP_002271934.1 209400356 6969680 complement(3401975..3403018) 1 NC_011353.1 identified by match to protein family HMM PF06674; hypothetical protein 3403018 6969680 ECH74115_3687 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271934.1 3401975 R 444450 CDS YP_002271935.1 209399744 6971554 complement(3403144..3403719) 1 NC_011353.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052; NUDIX family hydrolase 3403719 6971554 ECH74115_3688 Escherichia coli O157:H7 str. EC4115 NUDIX family hydrolase YP_002271935.1 3403144 R 444450 CDS YP_002271936.1 209396864 6970900 complement(3403787..3405766) 1 NC_011353.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3405766 aegA 6970900 aegA Escherichia coli O157:H7 str. EC4115 oxidoreductase Fe-S binding subunit YP_002271936.1 3403787 R 444450 CDS YP_002271937.1 209396261 6967799 3405972..3407672 1 NC_011353.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarQ 3407672 narQ 6967799 narQ Escherichia coli O157:H7 str. EC4115 nitrate/nitrite sensor protein NarQ YP_002271937.1 3405972 D 444450 CDS YP_002271938.1 209398035 6967154 3407836..3410949 1 NC_011353.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; aminoglycoside/multidrug efflux system 3410949 acrD 6967154 acrD Escherichia coli O157:H7 str. EC4115 aminoglycoside/multidrug efflux system YP_002271938.1 3407836 D 444450 CDS YP_002271939.1 209396217 6969048 3411488..3411844 1 NC_011353.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 3411844 6969048 ECH74115_3692 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271939.1 3411488 D 444450 CDS YP_002271940.1 209396481 6967106 3411848..3412975 1 NC_011353.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 3412975 dapE 6967106 dapE Escherichia coli O157:H7 str. EC4115 succinyl-diaminopimelate desuccinylase YP_002271940.1 3411848 D 444450 CDS YP_002271941.1 209398415 6967393 3413003..3413203 1 NC_011353.1 hypothetical protein 3413203 6967393 ECH74115_3694 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271941.1 3413003 D 444450 CDS YP_002271942.1 209399161 6969462 complement(3413284..3413982) 1 NC_011353.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 3413982 6969462 ECH74115_3695 Escherichia coli O157:H7 str. EC4115 esterase YpfH YP_002271942.1 3413284 R 444450 CDS YP_002271943.1 209397566 6970269 complement(3414056..3416071) 1 NC_011353.1 identified by match to protein family HMM PF00583; match to protein family HMM PF05127; hypothetical protein 3416071 6970269 ECH74115_3696 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271943.1 3414056 R 444450 CDS YP_002271944.1 209398291 6968542 complement(3416086..3416949) 1 NC_011353.1 identified by match to protein family HMM PF04228; hypothetical protein 3416949 6968542 ECH74115_3697 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271944.1 3416086 R 444450 CDS YP_002271945.1 209396021 6969325 complement(3417117..3417830) 1 NC_011353.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 3417830 purC 6969325 purC Escherichia coli O157:H7 str. EC4115 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_002271945.1 3417117 R 444450 CDS YP_002271946.1 209396761 6966895 complement(3418043..3419077) 1 NC_011353.1 identified by match to protein family HMM PF06804; lipoprotein 3419077 6966895 ECH74115_3699 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002271946.1 3418043 R 444450 CDS YP_002271947.1 209396670 6967689 complement(3419094..3419972) 1 NC_011353.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3419972 dapA 6967689 dapA Escherichia coli O157:H7 str. EC4115 dihydrodipicolinate synthase YP_002271947.1 3419094 R 444450 CDS YP_002271948.1 209399688 6967591 3420118..3420690 1 NC_011353.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 3420690 gcvR 6967591 gcvR Escherichia coli O157:H7 str. EC4115 glycine cleavage system transcriptional repressor YP_002271948.1 3420118 D 444450 CDS YP_002271949.1 209396765 6970838 3420690..3421160 1 NC_011353.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 3421160 bcp 6970838 bcp Escherichia coli O157:H7 str. EC4115 thioredoxin-dependent thiol peroxidase YP_002271949.1 3420690 D 444450 CDS YP_002271950.1 209397372 6967694 3421413..3422030 1 NC_011353.1 identified by match to protein family HMM PF00037; hydrogenase-4 subunit A 3422030 hyfA 6967694 hyfA Escherichia coli O157:H7 str. EC4115 hydrogenase-4 subunit A YP_002271950.1 3421413 D 444450 CDS YP_002271951.1 209398249 6968338 3422030..3424048 1 NC_011353.1 identified by match to protein family HMM PF00361; hydrogenase 4 subunit B 3424048 hyfB 6968338 hyfB Escherichia coli O157:H7 str. EC4115 hydrogenase 4 subunit B YP_002271951.1 3422030 D 444450 CDS YP_002271952.1 209397661 6969281 3424059..3425006 1 NC_011353.1 identified by match to protein family HMM PF00146; hydrogenase-4 subunit C 3425006 hyfC 6969281 hyfC Escherichia coli O157:H7 str. EC4115 hydrogenase-4 subunit C YP_002271952.1 3424059 D 444450 CDS YP_002271953.1 209396766 6968644 3425023..3426462 1 NC_011353.1 identified by match to protein family HMM PF00361; hydrogenase 4 subunit D 3426462 6968644 ECH74115_3706 Escherichia coli O157:H7 str. EC4115 hydrogenase 4 subunit D YP_002271953.1 3425023 D 444450 CDS YP_002271954.1 209396043 6967695 3426474..3427124 1 NC_011353.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 3427124 hyfE 6967695 hyfE Escherichia coli O157:H7 str. EC4115 hydrogenase 4 membrane subunit YP_002271954.1 3426474 D 444450 CDS YP_002271955.1 209400562 6966919 3427144..3428709 1 NC_011353.1 identified by match to protein family HMM PF00361; hydrogenase 4 subunit F 3428709 6966919 ECH74115_3708 Escherichia coli O157:H7 str. EC4115 hydrogenase 4 subunit F YP_002271955.1 3427144 D 444450 CDS YP_002271956.1 209399980 6971771 3428699..3430414 1 NC_011353.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346; hydrogenase-4, G subunit 3430414 6971771 ECH74115_3709 Escherichia coli O157:H7 str. EC4115 hydrogenase-4, G subunit YP_002271956.1 3428699 D 444450 CDS YP_002271957.1 209399054 6971152 3430424..3430969 1 NC_011353.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 3430969 6971152 ECH74115_3710 Escherichia coli O157:H7 str. EC4115 hydrogenase 4 subunit H YP_002271957.1 3430424 D 444450 CDS YP_002271958.1 209398464 6970156 3430966..3431724 1 NC_011353.1 identified by match to protein family HMM PF01058; hydrogenase-4, I subunit 3431724 6970156 ECH74115_3711 Escherichia coli O157:H7 str. EC4115 hydrogenase-4, I subunit YP_002271958.1 3430966 D 444450 CDS YP_002271959.1 209399076 6969517 3431717..3432130 1 NC_011353.1 identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein HycH 3432130 6969517 ECH74115_3712 Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase maturation protein HycH YP_002271959.1 3431717 D 444450 CDS YP_002271960.1 209396720 6970178 3432160..3434172 1 NC_011353.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; formate hydrogenlyase transcriptional activator 3434172 6970178 ECH74115_3713 Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase transcriptional activator YP_002271960.1 3432160 D 444450 CDS YP_002271961.1 209397824 6967646 3434194..3435042 1 NC_011353.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; formate transporter 3435042 focB 6967646 focB Escherichia coli O157:H7 str. EC4115 formate transporter YP_002271961.1 3434194 D 444450 CDS YP_002271962.1 209395768 6968815 complement(3435080..3436141) 1 NC_011353.1 identified by match to protein family HMM PF01594; permease, PerM family 3436141 6968815 ECH74115_3715 Escherichia coli O157:H7 str. EC4115 permease, PerM family YP_002271962.1 3435080 R 444450 CDS YP_002271963.1 209399555 6966624 3436354..3437817 1 NC_011353.1 identified by match to protein family HMM PF01435; M48 family peptidase 3437817 6966624 ECH74115_3716 Escherichia coli O157:H7 str. EC4115 M48 family peptidase YP_002271963.1 3436354 D 444450 CDS YP_002271964.1 209397583 6970693 3437838..3438197 1 NC_011353.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 3438197 arsC1 6970693 arsC1 Escherichia coli O157:H7 str. EC4115 arsenate reductase YP_002271964.1 3437838 D 444450 CDS YP_002271965.1 209400783 6968561 complement(3438335..3439081) 1 NC_011353.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 3439081 hda 6968561 hda Escherichia coli O157:H7 str. EC4115 DNA replication initiation factor YP_002271965.1 3438335 R 444450 CDS YP_002271966.1 209398719 6972008 complement(3439131..3440420) 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil transporter 3440420 uraA 6972008 uraA Escherichia coli O157:H7 str. EC4115 uracil transporter YP_002271966.1 3439131 R 444450 CDS YP_002271967.1 209395970 6969791 complement(3440506..3441132) 1 NC_011353.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 3441132 upp 6969791 upp Escherichia coli O157:H7 str. EC4115 uracil phosphoribosyltransferase YP_002271967.1 3440506 R 444450 CDS YP_002271968.1 209395985 6967492 3441457..3442494 1 NC_011353.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 3442494 purM 6967492 purM Escherichia coli O157:H7 str. EC4115 phosphoribosylaminoimidazole synthetase YP_002271968.1 3441457 D 444450 CDS YP_002271969.1 209395788 6966855 3442494..3443132 1 NC_011353.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3443132 purN 6966855 purN Escherichia coli O157:H7 str. EC4115 phosphoribosylglycinamide formyltransferase YP_002271969.1 3442494 D 444450 CDS YP_002271970.1 209399123 6966644 3443303..3445369 1 NC_011353.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3445369 ppk 6966644 ppk Escherichia coli O157:H7 str. EC4115 polyphosphate kinase YP_002271970.1 3443303 D 444450 CDS YP_002271971.1 209398375 6970225 3445374..3446915 1 NC_011353.1 identified by match to protein family HMM PF02541; exopolyphosphatase 3446915 ppx 6970225 ppx Escherichia coli O157:H7 str. EC4115 exopolyphosphatase YP_002271971.1 3445374 D 444450 CDS YP_002271972.1 209400743 6969418 complement(3446954..3449197) 1 NC_011353.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231; cytochrome C-type biogenesis protein 3449197 6969418 ECH74115_3726 Escherichia coli O157:H7 str. EC4115 cytochrome C-type biogenesis protein YP_002271972.1 3446954 R 444450 CDS YP_002271973.1 209399985 6971968 complement(3449379..3449531) 1 NC_011353.1 hypothetical protein 3449531 6971968 ECH74115_3727 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271973.1 3449379 R 444450 CDS YP_002271974.1 209396892 6971157 3449549..3449740 1 NC_011353.1 hypothetical protein 3449740 6971157 ECH74115_3728 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271974.1 3449549 D 444450 CDS YP_002271975.1 209396163 6967829 3450054..3450569 1 NC_011353.1 identified by match to protein family HMM PF05433; surface antigen family protein 3450569 6967829 ECH74115_3729 Escherichia coli O157:H7 str. EC4115 surface antigen family protein YP_002271975.1 3450054 D 444450 CDS YP_002271976.1 209395734 6967046 3450585..3451124 1 NC_011353.1 hypothetical protein 3451124 6967046 ECH74115_3730 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271976.1 3450585 D 444450 CDS YP_002271977.1 209397616 6966589 complement(3451217..3452794) 1 NC_011353.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3452794 guaA 6966589 guaA Escherichia coli O157:H7 str. EC4115 GMP synthase YP_002271977.1 3451217 R 444450 CDS YP_002271978.1 209397313 6968597 complement(3452863..3454374) 1 NC_011353.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 3454374 guaB 6968597 guaB Escherichia coli O157:H7 str. EC4115 inosine 5'-monophosphate dehydrogenase YP_002271978.1 3452863 R 444450 CDS YP_002271979.1 209400584 6968275 3454491..3455861 1 NC_011353.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3455861 xseA 6968275 xseA Escherichia coli O157:H7 str. EC4115 exodeoxyribonuclease VII large subunit YP_002271979.1 3454491 D 444450 CDS YP_002271980.1 209396202 6971795 complement(3455858..3456073) 1 NC_011353.1 identified by match to protein family HMM PF07191; hypothetical protein 3456073 6971795 ECH74115_3733 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271980.1 3455858 R 444450 CDS YP_002271981.1 209399678 6967089 complement(3456142..3457614) 1 NC_011353.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 3457614 engA 6967089 engA Escherichia coli O157:H7 str. EC4115 GTP-binding protein EngA YP_002271981.1 3456142 R 444450 CDS YP_002271982.1 209398578 6970827 complement(3457732..3458910) 1 NC_011353.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 3458910 6970827 ECH74115_3736 Escherichia coli O157:H7 str. EC4115 outer membrane protein assembly complex subunit YfgL YP_002271982.1 3457732 R 444450 CDS YP_002271983.1 209397682 6969639 complement(3458921..3459541) 1 NC_011353.1 hypothetical protein 3459541 6969639 ECH74115_3737 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271983.1 3458921 R 444450 CDS YP_002271984.1 209398087 6968665 complement(3459559..3460833) 1 NC_011353.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 3460833 hisS 6968665 hisS Escherichia coli O157:H7 str. EC4115 histidyl-tRNA synthetase YP_002271984.1 3459559 R 444450 CDS YP_002271985.1 209397492 6972305 complement(3460944..3462062) 1 NC_011353.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3462062 ispG 6972305 ispG Escherichia coli O157:H7 str. EC4115 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002271985.1 3460944 R 444450 CDS YP_002271986.1 209396298 6968464 complement(3462089..3463102) 1 NC_011353.1 identified by match to protein family HMM PF01381; cytoskeletal protein RodZ 3463102 6968464 ECH74115_3741 Escherichia coli O157:H7 str. EC4115 cytoskeletal protein RodZ YP_002271986.1 3462089 R 444450 CDS YP_002271987.1 209400754 6967193 complement(3463387..3464541) 1 NC_011353.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 3464541 6967193 ECH74115_3742 Escherichia coli O157:H7 str. EC4115 ribosomal RNA large subunit methyltransferase N YP_002271987.1 3463387 R 444450 CDS YP_002271988.1 209399802 6971979 complement(3464691..3465122) 1 NC_011353.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 3465122 ndk 6971979 ndk Escherichia coli O157:H7 str. EC4115 nucleoside diphosphate kinase YP_002271988.1 3464691 R 444450 CDS YP_002271989.1 209398407 6970959 complement(3465263..3466117) 1 NC_011353.1 identified by match to protein family HMM PF00037; polyferredoxin 3466117 6970959 ECH74115_3744 Escherichia coli O157:H7 str. EC4115 polyferredoxin YP_002271989.1 3465263 R 444450 CDS YP_002271990.1 209397088 6969453 complement(3466117..3466938) 1 NC_011353.1 anaerobic dimethyl sulfoxide reductase subunit C 3466938 6969453 ECH74115_3745 Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase subunit C YP_002271990.1 3466117 R 444450 CDS YP_002271991.1 209397819 6968034 complement(3466931..3467560) 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951; dimethylsulfoxide reductase subunit B 3467560 dmsB 6968034 dmsB Escherichia coli O157:H7 str. EC4115 dimethylsulfoxide reductase subunit B YP_002271991.1 3466931 R 444450 CDS YP_002271992.1 209395905 6968810 complement(3467557..3469938) 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 3469938 6968810 ECH74115_3747 Escherichia coli O157:H7 str. EC4115 anaerobic dimethyl sulfoxide reductase subunit A YP_002271992.1 3467557 R 444450 CDS YP_002271993.1 209396651 6966771 complement(3470102..3472414) 1 NC_011353.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 3472414 pbpC 6966771 pbpC Escherichia coli O157:H7 str. EC4115 penicillin-binding protein 1C YP_002271993.1 3470102 R 444450 CDS YP_002271994.1 209400655 6967571 complement(3472415..3477376) 1 NC_011353.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin domain-containing protein 3477376 6967571 ECH74115_3749 Escherichia coli O157:H7 str. EC4115 alpha-2-macroglobulin domain-containing protein YP_002271994.1 3472415 R 444450 CDS YP_002271995.1 209398755 6971871 3477583..3478428 1 NC_011353.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 3478428 sseA 6971871 sseA Escherichia coli O157:H7 str. EC4115 3-mercaptopyruvate sulfurtransferase YP_002271995.1 3477583 D 444450 CDS YP_002271996.1 209397515 6972311 complement(3478928..3479704) 1 NC_011353.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 3479704 sseB 6972311 sseB Escherichia coli O157:H7 str. EC4115 enhanced serine sensitivity protein SseB YP_002271996.1 3478928 R 444450 CDS YP_002271997.1 209396200 6968488 complement(3479847..3481130) 1 NC_011353.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 3481130 pepB 6968488 pepB Escherichia coli O157:H7 str. EC4115 aminopeptidase B YP_002271997.1 3479847 R 444450 CDS YP_002271998.1 209398449 6967087 complement(3481308..3481508) 1 NC_011353.1 identified by match to protein family HMM PF04384; match to protein family HMM TIGR03412; hypothetical protein 3481508 iscX 6967087 iscX Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002271998.1 3481308 R 444450 CDS YP_002271999.1 209399066 6969501 complement(3481520..3481855) 1 NC_011353.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007; ferredoxin, 2Fe-2S type, ISC system 3481855 fdx 6969501 fdx Escherichia coli O157:H7 str. EC4115 ferredoxin, 2Fe-2S type, ISC system YP_002271999.1 3481520 R 444450 CDS YP_002272000.1 209397639 6970168 complement(3481857..3483707) 1 NC_011353.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 3483707 hscA 6970168 hscA Escherichia coli O157:H7 str. EC4115 chaperone protein HscA YP_002272000.1 3481857 R 444450 CDS YP_002272001.1 209396107 6968622 complement(3483724..3484239) 1 NC_011353.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 3484239 hscB 6968622 hscB Escherichia coli O157:H7 str. EC4115 co-chaperone HscB YP_002272001.1 3483724 R 444450 CDS YP_002272002.1 209399835 6966986 complement(3484247..3484363) 1 NC_011353.1 identified by glimmer; hypothetical protein 3484363 6966986 ECH74115_3759 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272002.1 3484247 R 444450 CDS YP_002272003.1 209400619 6970992 complement(3484335..3484664) 1 NC_011353.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 3484664 iscA 6970992 iscA Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster assembly protein YP_002272003.1 3484335 R 444450 CDS YP_002272004.1 209398396 6971831 complement(3484675..3485061) 1 NC_011353.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999; scaffold protein 3485061 iscU 6971831 iscU Escherichia coli O157:H7 str. EC4115 scaffold protein YP_002272004.1 3484675 R 444450 CDS YP_002272005.1 209398422 6969440 complement(3485089..3486303) 1 NC_011353.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 3486303 iscS 6969440 iscS Escherichia coli O157:H7 str. EC4115 cysteine desulfurase YP_002272005.1 3485089 R 444450 CDS YP_002272006.1 209399149 6969470 complement(3486415..3486903) 1 NC_011353.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 3486903 iscR 6969470 iscR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator IscR YP_002272006.1 3486415 R 444450 CDS YP_002272007.1 209397596 6970256 complement(3487204..3487941) 1 NC_011353.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; TrmH family RNA methyltransferase 3487941 6970256 ECH74115_3764 Escherichia coli O157:H7 str. EC4115 TrmH family RNA methyltransferase YP_002272007.1 3487204 R 444450 CDS YP_002272008.1 209395926 6968575 3488060..3488863 1 NC_011353.1 identified by match to protein family HMM PF00459; inositol monophosphatase 3488863 suhB 6968575 suhB Escherichia coli O157:H7 str. EC4115 inositol monophosphatase YP_002272008.1 3488060 D 444450 CDS YP_002272009.1 209398901 6966793 3489008..3489862 1 NC_011353.1 hypothetical protein 3489862 6966793 ECH74115_3766 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272009.1 3489008 D 444450 CDS YP_002272010.1 209400112 6969991 3490053..3491333 1 NC_011353.1 identified by match to protein family HMM PF00874; stationary phase inducible protein CsiE 3491333 csiE 6969991 csiE Escherichia coli O157:H7 str. EC4115 stationary phase inducible protein CsiE YP_002272010.1 3490053 D 444450 CDS YP_002272011.1 209399133 6971295 complement(3491325..3492464) 1 NC_011353.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 3492464 hcaT 6971295 hcaT Escherichia coli O157:H7 str. EC4115 3-phenylpropionic acid transporter YP_002272011.1 3491325 R 444450 CDS YP_002272012.1 209400694 6970236 complement(3492624..3493514) 1 NC_011353.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 3493514 hcaR 6970236 hcaR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator HcaR YP_002272012.1 3492624 R 444450 CDS YP_002272013.1 209400100 6966724 3495008..3495526 1 NC_011353.1 identified by match to protein family HMM PF00866; 3-phenylpropionate dioxygenase subunit beta 3495526 hcaF 6966724 hcaF Escherichia coli O157:H7 str. EC4115 3-phenylpropionate dioxygenase subunit beta YP_002272013.1 3495008 D 444450 CDS YP_002272014.1 209397149 6971282 3495526..3495846 1 NC_011353.1 identified by match to protein family HMM PF00355; 3-phenylpropionate dioxygenase ferredoxin subunit 3495846 hcaC 6971282 hcaC Escherichia coli O157:H7 str. EC4115 3-phenylpropionate dioxygenase ferredoxin subunit YP_002272014.1 3495526 D 444450 CDS YP_002272015.1 209397724 6968101 3495843..3496655 1 NC_011353.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 3496655 hcaB 6968101 hcaB Escherichia coli O157:H7 str. EC4115 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_002272015.1 3495843 D 444450 CDS YP_002272016.1 209399212 6968709 3496665..3497867 1 NC_011353.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; phenylpropionate dioxygenase ferredoxin reductase subunit 3497867 hcaD 6968709 hcaD Escherichia coli O157:H7 str. EC4115 phenylpropionate dioxygenase ferredoxin reductase subunit YP_002272016.1 3496665 D 444450 CDS YP_002272017.1 209395795 6970321 3497964..3498386 1 NC_011353.1 identified by match to protein family HMM PF07681; inner membrane protein YphA 3498386 6970321 ECH74115_3775 Escherichia coli O157:H7 str. EC4115 inner membrane protein YphA YP_002272017.1 3497964 D 444450 CDS YP_002272018.1 209397866 6966651 complement(3498434..3499306) 1 NC_011353.1 identified by match to protein family HMM PF01263; aldose 1-epimerase family protein 3499306 6966651 ECH74115_3776 Escherichia coli O157:H7 str. EC4115 aldose 1-epimerase family protein YP_002272018.1 3498434 R 444450 CDS YP_002272019.1 209399954 6971748 complement(3500445..3501443) 1 NC_011353.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 3501443 6971748 ECH74115_3779 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter permease YP_002272019.1 3500445 R 444450 CDS YP_002272020.1 209396711 6971122 complement(3501468..3502979) 1 NC_011353.1 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 3502979 6971122 ECH74115_3780 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter ATP-binding protein YP_002272020.1 3501468 R 444450 CDS YP_002272021.1 209396140 6967636 complement(3503002..3503985) 1 NC_011353.1 identified by match to protein family HMM PF00532; sugar ABC transporter substrate-binding protein 3503985 6967636 ECH74115_3781 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter substrate-binding protein YP_002272021.1 3503002 R 444450 CDS YP_002272022.1 209397136 6967023 complement(3504082..3507456) 1 NC_011353.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 3507456 6967023 ECH74115_3782 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272022.1 3504082 R 444450 CDS YP_002272023.1 209397633 6968087 3507481..3508674 1 NC_011353.1 identified by match to protein family HMM PF00480; ROK family protein 3508674 6968087 ECH74115_3783 Escherichia coli O157:H7 str. EC4115 ROK family protein YP_002272023.1 3507481 D 444450 CDS YP_002272024.1 209398610 6968615 complement(3508737..3509990) 1 NC_011353.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3509990 glyA 6968615 glyA Escherichia coli O157:H7 str. EC4115 serine hydroxymethyltransferase YP_002272024.1 3508737 R 444450 CDS YP_002272025.1 209398373 6969673 3510142..3510270 1 NC_011353.1 hypothetical protein 3510270 6969673 ECH74115_3785 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272025.1 3510142 D 444450 CDS YP_002272026.1 209396380 6969416 3510318..3511508 1 NC_011353.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 3511508 hmp 6969416 hmp Escherichia coli O157:H7 str. EC4115 nitric oxide dioxygenase YP_002272026.1 3510318 D 444450 CDS YP_002272027.1 209395723 6967285 complement(3511553..3511891) 1 NC_011353.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 3511891 glnB 6967285 glnB Escherichia coli O157:H7 str. EC4115 nitrogen regulatory protein P-II 1 YP_002272027.1 3511553 R 444450 CDS YP_002272028.1 209397901 6966578 complement(3511952..3513286) 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728; sigma-54 dependent response regulator 3513286 6966578 ECH74115_3788 Escherichia coli O157:H7 str. EC4115 sigma-54 dependent response regulator YP_002272028.1 3511952 R 444450 CDS YP_002272029.1 209396789 6968899 complement(3513276..3513911) 1 NC_011353.1 hypothetical protein 3513911 6968899 ECH74115_3789 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272029.1 3513276 R 444450 CDS YP_002272030.1 209398684 6967720 complement(3514154..3515581) 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 3515581 6967720 ECH74115_3790 Escherichia coli O157:H7 str. EC4115 sensor histidine kinase YP_002272030.1 3514154 R 444450 CDS YP_002272031.1 209398316 6972286 complement(3516157..3520044) 1 NC_011353.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 3520044 purL 6972286 purL Escherichia coli O157:H7 str. EC4115 phosphoribosylformylglycinamidine synthase YP_002272031.1 3516157 R 444450 CDS YP_002272032.1 209399097 6969354 3520301..3521857 1 NC_011353.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 3521857 6969354 ECH74115_3794 Escherichia coli O157:H7 str. EC4115 transglycosylase YP_002272032.1 3520301 D 444450 CDS YP_002272033.1 209400171 6970199 complement(3521854..3522357) 1 NC_011353.1 identified by match to protein family HMM PF00383; tRNA-specific adenosine deaminase 3522357 tadA 6970199 tadA Escherichia coli O157:H7 str. EC4115 tRNA-specific adenosine deaminase YP_002272033.1 3521854 R 444450 CDS YP_002272034.1 209397529 6971358 complement(3522415..3523050) 1 NC_011353.1 identified by match to protein family HMM TIGR01545; hypothetical protein 3523050 yhfB 6971358 yhfB Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272034.1 3522415 R 444450 CDS YP_002272035.1 209398568 6968502 3523259..3524107 1 NC_011353.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; DNA-binding transcriptional regulator 3524107 6968502 ECH74115_3796 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002272035.1 3523259 D 444450 CDS YP_002272036.1 209399302 6969629 3524139..3524423 1 NC_011353.1 4Fe-4S binding protein 3524423 6969629 ECH74115_3797 Escherichia coli O157:H7 str. EC4115 4Fe-4S binding protein YP_002272036.1 3524139 D 444450 CDS YP_002272037.1 209397069 6970419 3524890..3525012 1 NC_011353.1 identified by glimmer; hypothetical protein 3525012 6970419 ECH74115_3798 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272037.1 3524890 D 444450 CDS YP_002272038.1 209397806 6968015 complement(3525119..3525499) 1 NC_011353.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 3525499 acpS 6968015 acpS Escherichia coli O157:H7 str. EC4115 4'-phosphopantetheinyl transferase YP_002272038.1 3525119 R 444450 CDS YP_002272039.1 209396227 6968796 complement(3525499..3526230) 1 NC_011353.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 3526230 pdxJ 6968796 pdxJ Escherichia coli O157:H7 str. EC4115 pyridoxine 5'-phosphate synthase YP_002272039.1 3525499 R 444450 CDS YP_002272040.1 209396972 6967117 complement(3526242..3526970) 1 NC_011353.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 3526970 recO 6967117 recO Escherichia coli O157:H7 str. EC4115 DNA repair protein RecO YP_002272040.1 3526242 R 444450 CDS YP_002272041.1 209400046 6967912 complement(3526982..3527887) 1 NC_011353.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 3527887 era 6967912 era Escherichia coli O157:H7 str. EC4115 GTP-binding protein Era YP_002272041.1 3526982 R 444450 CDS YP_002272042.1 209400787 6971223 complement(3527884..3528564) 1 NC_011353.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 3528564 rnc 6971223 rnc Escherichia coli O157:H7 str. EC4115 ribonuclease III YP_002272042.1 3527884 R 444450 CDS YP_002272043.1 209400512 6972013 complement(3528837..3529811) 1 NC_011353.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 3529811 lepB 6972013 lepB Escherichia coli O157:H7 str. EC4115 signal peptidase I YP_002272043.1 3528837 R 444450 CDS YP_002272044.1 209398655 6971718 complement(3529827..3531626) 1 NC_011353.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 3531626 lepA 6971718 lepA Escherichia coli O157:H7 str. EC4115 GTP-binding protein LepA YP_002272044.1 3529827 R 444450 CDS YP_002272045.1 209397018 6969724 complement(3531824..3532303) 1 NC_011353.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 3532303 rseC 6969724 rseC Escherichia coli O157:H7 str. EC4115 SoxR reducing system protein RseC YP_002272045.1 3531824 R 444450 CDS YP_002272046.1 209396669 6967962 complement(3532300..3533256) 1 NC_011353.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 3533256 rseB 6967962 rseB Escherichia coli O157:H7 str. EC4115 periplasmic negative regulator of sigmaE YP_002272046.1 3532300 R 444450 CDS YP_002272047.1 209395903 6967590 complement(3533256..3533894) 1 NC_011353.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873; anti-RNA polymerase sigma factor SigE 3533894 rseA 6967590 rseA Escherichia coli O157:H7 str. EC4115 anti-RNA polymerase sigma factor SigE YP_002272047.1 3533256 R 444450 CDS YP_002272048.1 209400807 6966769 complement(3533927..3534502) 1 NC_011353.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 3534502 rpoE 6966769 rpoE Escherichia coli O157:H7 str. EC4115 RNA polymerase sigma factor RpoE YP_002272048.1 3533927 R 444450 CDS YP_002272049.1 209399650 6972035 3534940..3536532 1 NC_011353.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 3536532 nadB 6972035 nadB Escherichia coli O157:H7 str. EC4115 L-aspartate oxidase YP_002272049.1 3534940 D 444450 CDS YP_002272050.1 209400058 6970795 complement(3536517..3537254) 1 NC_011353.1 identified by match to protein family HMM PF05175; methyltransferase 3537254 6970795 ECH74115_3811 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002272050.1 3536517 R 444450 CDS YP_002272051.1 209397789 6971237 3537386..3538720 1 NC_011353.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3538720 srmB 6971237 srmB Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase SrmB YP_002272051.1 3537386 D 444450 CDS YP_002272052.1 209397058 6968778 complement(3538753..3539679) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3539679 6968778 ECH74115_3814 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002272052.1 3538753 R 444450 CDS YP_002272053.1 209396559 6968004 3539737..3540324 1 NC_011353.1 identified by match to protein family HMM PF01810; neutral amino-acid efflux protein 3540324 6968004 ECH74115_3815 Escherichia coli O157:H7 str. EC4115 neutral amino-acid efflux protein YP_002272053.1 3539737 D 444450 CDS YP_002272054.1 209396160 6967473 complement(3540380..3540763) 1 NC_011353.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 3540763 grcA 6967473 grcA Escherichia coli O157:H7 str. EC4115 autonomous glycyl radical cofactor GrcA YP_002272054.1 3540380 R 444450 CDS YP_002272055.1 209398327 6967043 3541068..3541757 1 NC_011353.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3541757 ung 6967043 ung Escherichia coli O157:H7 str. EC4115 uracil-DNA glycosylase YP_002272055.1 3541068 D 444450 CDS YP_002272056.1 209397290 6969365 complement(3541805..3542842) 1 NC_011353.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; methyltransferase 3542842 6969365 ECH74115_3818 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002272056.1 3541805 R 444450 CDS YP_002272057.1 209396514 6968251 3543049..3543468 1 NC_011353.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2 3543468 6968251 ECH74115_3819 Escherichia coli O157:H7 str. EC4115 thioredoxin 2 YP_002272057.1 3543049 D 444450 CDS YP_002272058.1 209400827 6967426 3543537..3544235 1 NC_011353.1 identified by match to protein family HMM PF03942; DTW domain-containing protein 3544235 6967426 ECH74115_3820 Escherichia coli O157:H7 str. EC4115 DTW domain-containing protein YP_002272058.1 3543537 D 444450 CDS YP_002272059.1 209400567 6972055 3544267..3546927 1 NC_011353.1 identified by match to protein family HMM PF00583; match to protein family HMM PF02629; GNAT family acetyltransferase 3546927 6972055 ECH74115_3821 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002272059.1 3544267 D 444450 CDS YP_002272060.1 209399593 6971777 3547041..3548396 1 NC_011353.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3548396 pssA 6971777 pssA Escherichia coli O157:H7 str. EC4115 phosphatidylserine synthase YP_002272060.1 3547041 D 444450 CDS YP_002272061.1 209397756 6970734 3548421..3548765 1 NC_011353.1 hypothetical protein 3548765 6970734 ECH74115_3824 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272061.1 3548421 D 444450 CDS YP_002272062.1 209398967 6968743 complement(3548762..3550141) 1 NC_011353.1 identified by match to protein family HMM PF00083; alpha-ketoglutarate transporter 3550141 kgtP 6968743 kgtP Escherichia coli O157:H7 str. EC4115 alpha-ketoglutarate transporter YP_002272062.1 3548762 R 444450 CDS YP_002272063.1 209397097 6970063 3550021..3550302 1 NC_011353.1 identified by glimmer; hypothetical protein 3550302 6970063 ECH74115_3825 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272063.1 3550021 D 444450 CDS YP_002272064.1 209398893 6972282 3555653..3555787 1 NC_011353.1 hypothetical protein 3555787 6972282 ECH74115_3832 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272064.1 3555653 D 444450 CDS YP_002272065.1 209397795 6969982 complement(3555828..3558401) 1 NC_011353.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346; protein disaggregation chaperone 3558401 clpB 6969982 clpB Escherichia coli O157:H7 str. EC4115 protein disaggregation chaperone YP_002272065.1 3555828 R 444450 CDS YP_002272066.1 209396881 6968784 complement(3558531..3559262) 1 NC_011353.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 3559262 6968784 ECH74115_3834 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272066.1 3558531 R 444450 CDS YP_002272067.1 209396635 6967818 complement(3559259..3560239) 1 NC_011353.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 3560239 rluD 6967818 rluD Escherichia coli O157:H7 str. EC4115 23S rRNA pseudouridine synthase D YP_002272067.1 3559259 R 444450 CDS YP_002272068.1 209395708 6967555 3560374..3561111 1 NC_011353.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3561111 6967555 ECH74115_3836 Escherichia coli O157:H7 str. EC4115 outer membrane protein assembly complex subunit YfiO YP_002272068.1 3560374 D 444450 CDS YP_002272069.1 209399823 6966562 3561382..3561723 1 NC_011353.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3561723 6966562 ECH74115_3837 Escherichia coli O157:H7 str. EC4115 translation inhibitor protein RaiA YP_002272069.1 3561382 D 444450 CDS YP_002272070.1 209399059 6970980 3561973..3563133 1 NC_011353.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3563133 pheA 6970980 pheA Escherichia coli O157:H7 str. EC4115 bifunctional chorismate mutase/prephenate dehydratase YP_002272070.1 3561973 D 444450 CDS YP_002272071.1 209399005 6970161 complement(3563176..3564297) 1 NC_011353.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 3564297 tyrA 6970161 tyrA Escherichia coli O157:H7 str. EC4115 bifunctional chorismate mutase/prephenate dehydrogenase YP_002272071.1 3563176 R 444450 CDS YP_002272072.1 209398239 6970104 complement(3564308..3565378) 1 NC_011353.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3565378 aroF 6970104 aroF Escherichia coli O157:H7 str. EC4115 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002272072.1 3564308 R 444450 CDS YP_002272073.1 209396960 6969271 3565588..3565953 1 NC_011353.1 hypothetical protein 3565953 6969271 ECH74115_3841 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272073.1 3565588 D 444450 CDS YP_002272074.1 209397850 6967899 3566103..3566621 1 NC_011353.1 hypothetical protein 3566621 6967899 ECH74115_3842 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272074.1 3566103 D 444450 CDS YP_002272075.1 209397410 6968842 3566614..3567837 1 NC_011353.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein 3567837 6968842 ECH74115_3843 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272075.1 3566614 D 444450 CDS YP_002272076.1 209399323 6968378 3567853..3568335 1 NC_011353.1 identified by match to protein family HMM PF00691; outer membrane lipoprotein 3568335 6968378 ECH74115_3844 Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein YP_002272076.1 3567853 D 444450 CDS YP_002272077.1 209398937 6970443 complement(3568412..3568759) 1 NC_011353.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3568759 rplS 6970443 rplS Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L19 YP_002272077.1 3568412 R 444450 CDS YP_002272078.1 209400862 6970031 complement(3568801..3569568) 1 NC_011353.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3569568 trmD 6970031 trmD Escherichia coli O157:H7 str. EC4115 tRNA (guanine-N(1)-)-methyltransferase YP_002272078.1 3568801 R 444450 CDS YP_002272079.1 209396490 6972093 complement(3569599..3570150) 1 NC_011353.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3570150 rimM 6972093 rimM Escherichia coli O157:H7 str. EC4115 16S rRNA-processing protein RimM YP_002272079.1 3569599 R 444450 CDS YP_002272080.1 209395757 6967402 complement(3570166..3570414) 1 NC_011353.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3570414 rpsP 6967402 rpsP Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S16 YP_002272080.1 3570166 R 444450 CDS YP_002272081.1 209398002 6966612 complement(3570551..3571912) 1 NC_011353.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 3571912 ffh 6966612 ffh Escherichia coli O157:H7 str. EC4115 signal recognition particle protein YP_002272081.1 3570551 R 444450 CDS YP_002272082.1 209397143 6969014 3572004..3572870 1 NC_011353.1 identified by match to protein family HMM PF01578; cytochrome C assembly protein 3572870 6969014 ECH74115_3850 Escherichia coli O157:H7 str. EC4115 cytochrome C assembly protein YP_002272082.1 3572004 D 444450 CDS YP_002272083.1 209400581 6967345 complement(3574232..3574825) 1 NC_011353.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 3574825 grpE 6967345 grpE Escherichia coli O157:H7 str. EC4115 heat shock protein GrpE YP_002272083.1 3574232 R 444450 CDS YP_002272084.1 209399606 6969725 3574948..3575826 1 NC_011353.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3575826 ppnK 6969725 ppnK Escherichia coli O157:H7 str. EC4115 inorganic polyphosphate/ATP-NAD kinase YP_002272084.1 3574948 D 444450 CDS YP_002272085.1 209397502 6970748 3575912..3577573 1 NC_011353.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; recombination and repair protein 3577573 recN 6970748 recN Escherichia coli O157:H7 str. EC4115 recombination and repair protein YP_002272085.1 3575912 D 444450 CDS YP_002272086.1 209396322 6968474 3577722..3578063 1 NC_011353.1 identified by match to protein family HMM PF04355; hypothetical protein 3578063 6968474 ECH74115_3857 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272086.1 3577722 D 444450 CDS YP_002272087.1 209396909 6967219 complement(3578125..3578415) 1 NC_011353.1 identified by match to protein family HMM PF03658; hypothetical protein 3578415 6967219 ECH74115_3858 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272087.1 3578125 R 444450 CDS YP_002272088.1 209396556 6967847 complement(3578405..3578881) 1 NC_011353.1 identified by match to protein family HMM PF03364; hypothetical protein 3578881 6967847 ECH74115_3859 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272088.1 3578405 R 444450 CDS YP_002272089.1 209399817 6967470 3579013..3579495 1 NC_011353.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3579495 smpB 6967470 smpB Escherichia coli O157:H7 str. EC4115 SsrA-binding protein YP_002272089.1 3579013 D 444450 CDS YP_002272090.1 209396959 6972438 3580341..3580589 1 NC_011353.1 identified by match to protein family HMM PF06183; hypothetical protein 3580589 6972438 ECH74115_3864 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272090.1 3580341 D 444450 CDS YP_002272091.1 209397455 6967898 complement(3580586..3580732) 1 NC_011353.1 hypothetical protein 3580732 6967898 ECH74115_3863 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272091.1 3580586 R 444450 CDS YP_002272092.1 209396248 6968426 3580752..3580913 1 NC_011353.1 hypothetical protein 3580913 6968426 ECH74115_3865 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272092.1 3580752 D 444450 CDS YP_002272093.1 209400486 6967140 complement(3581091..3581507) 1 NC_011353.1 identified by match to protein family HMM PF03278; EspM3 protein 3581507 6967140 ECH74115_3866 Escherichia coli O157:H7 str. EC4115 EspM3 protein YP_002272093.1 3581091 R 444450 CDS YP_002272094.1 209399673 6971691 complement(3581791..3581958) 1 NC_011353.1 identified by glimmer; hypothetical protein 3581958 6971691 ECH74115_3867 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272094.1 3581791 R 444450 CDS YP_002272095.1 209399286 6970820 complement(3582450..3582563) 1 NC_011353.1 identified by glimmer; hypothetical protein 3582563 6970820 ECH74115_3868 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272095.1 3582450 R 444450 CDS YP_002272096.1 209398113 6970402 3582593..3583651 1 NC_011353.1 hypothetical protein 3583651 6970402 ECH74115_3869 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272096.1 3582593 D 444450 CDS YP_002272097.1 209397447 6969132 complement(3583781..3584188) 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 3584188 6969132 ECH74115_3870 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272097.1 3583781 R 444450 CDS YP_002272098.1 209396681 6968417 complement(3584364..3584633) 1 NC_011353.1 prophage tail fiber C-terminus family protein 3584633 6968417 ECH74115_3871 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002272098.1 3584364 R 444450 CDS YP_002272099.1 209396326 6967602 3584632..3584799 1 NC_011353.1 hypothetical protein 3584799 6967602 ECH74115_3872 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272099.1 3584632 D 444450 CDS YP_002272100.1 209395741 6967223 3584851..3585177 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 3585177 6967223 ECH74115_3873 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002272100.1 3584851 D 444450 CDS YP_002272101.1 209396319 6966596 3585174..3586064 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 3586064 6966596 ECH74115_3874 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002272101.1 3585174 D 444450 CDS YP_002272102.1 209396903 6967215 complement(3586565..3586912) 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 3586912 6967215 ECH74115_3875 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002272102.1 3586565 R 444450 CDS YP_002272103.1 209400167 6967841 complement(3587365..3587595) 1 NC_011353.1 lysozyme 3587595 6967841 ECH74115_3876 Escherichia coli O157:H7 str. EC4115 lysozyme YP_002272103.1 3587365 R 444450 CDS YP_002272104.1 209400730 6971353 complement(3587646..3587990) 1 NC_011353.1 identified by match to protein family HMM PF07041; hypothetical protein 3587990 6971353 ECH74115_3877 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272104.1 3587646 R 444450 CDS YP_002272105.1 209398639 6971954 complement(3587995..3588210) 1 NC_011353.1 identified by match to protein family HMM PF04971; hypothetical protein 3588210 6971954 ECH74115_3878 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272105.1 3587995 R 444450 CDS YP_002272106.1 209399258 6969705 complement(3588360..3590213) 1 NC_011353.1 identified by match to protein family HMM PF03629; match to protein family HMM PF08410; hypothetical protein 3590213 6969705 ECH74115_3879 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272106.1 3588360 R 444450 CDS YP_002272107.1 209397150 6970373 complement(3590659..3590826) 1 NC_011353.1 hypothetical protein 3590826 6970373 ECH74115_3880 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272107.1 3590659 R 444450 CDS YP_002272108.1 209397740 6968102 complement(3590912..3591628) 1 NC_011353.1 hypothetical protein 3591628 6968102 ECH74115_3881 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272108.1 3590912 R 444450 CDS YP_002272109.1 209398289 6968725 complement(3591721..3591837) 1 NC_011353.1 identified by glimmer; hypothetical protein 3591837 6968725 ECH74115_3882 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272109.1 3591721 R 444450 CDS YP_002272110.1 209395755 6969323 complement(3591908..3592531) 1 NC_011353.1 identified by match to protein family HMM PF03589; antitermination protein Q 3592531 6969323 ECH74115_3883 Escherichia coli O157:H7 str. EC4115 antitermination protein Q YP_002272110.1 3591908 R 444450 CDS YP_002272111.1 209397632 6966610 complement(3592528..3593193) 1 NC_011353.1 identified by match to protein family HMM PF00149; serine/threonine-protein phosphatase 1 3593193 6966610 ECH74115_3884 Escherichia coli O157:H7 str. EC4115 serine/threonine-protein phosphatase 1 YP_002272111.1 3592528 R 444450 CDS YP_002272112.1 209397799 6968614 complement(3593190..3593801) 1 NC_011353.1 identified by match to protein family HMM PF05766; bacteriophage Lambda NinG protein 3593801 6968614 ECH74115_3885 Escherichia coli O157:H7 str. EC4115 bacteriophage Lambda NinG protein YP_002272112.1 3593190 R 444450 CDS YP_002272113.1 209398359 6968788 3594672..3595427 1 NC_011353.1 transposase InsI for insertion sequence element IS30B/C/D 3595427 6968788 ECH74115_3886 Escherichia coli O157:H7 str. EC4115 transposase InsI for insertion sequence element IS30B/C/D YP_002272113.1 3594672 D 444450 CDS YP_002272114.1 209399308 6969400 3595487..3595765 1 NC_011353.1 hypothetical protein 3595765 6969400 ECH74115_3887 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272114.1 3595487 D 444450 CDS YP_002272115.1 209399981 6970425 complement(3595841..3597055) 1 NC_011353.1 hypothetical protein 3597055 6970425 ECH74115_3888 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272115.1 3595841 R 444450 CDS YP_002272116.1 209396206 6971153 complement(3597595..3598065) 1 NC_011353.1 hypothetical protein 3598065 6971153 ECH74115_3889 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272116.1 3597595 R 444450 CDS YP_002272117.1 209396724 6967093 complement(3598106..3598327) 1 NC_011353.1 hypothetical protein 3598327 6967093 ECH74115_3890 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272117.1 3598106 R 444450 CDS YP_002272118.1 209396348 6967650 complement(3598505..3600136) 1 NC_011353.1 DNA-binding protein 3600136 6967650 ECH74115_3891 Escherichia coli O157:H7 str. EC4115 DNA-binding protein YP_002272118.1 3598505 R 444450 CDS YP_002272119.1 209398276 6967250 complement(3600133..3601446) 1 NC_011353.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family protein 3601446 6967250 ECH74115_3892 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family protein YP_002272119.1 3600133 R 444450 CDS YP_002272120.1 209396283 6966565 complement(3603282..3604133) 1 NC_011353.1 hypothetical protein 3604133 6966565 ECH74115_3894 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272120.1 3603282 R 444450 CDS YP_002272121.1 209399930 6967177 complement(3604560..3609275) 1 NC_011353.1 identified by glimmer; hypothetical protein 3609275 6967177 ECH74115_3895 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272121.1 3604560 R 444450 CDS YP_002272122.1 209399175 6971095 complement(3609211..3609330) 1 NC_011353.1 identified by glimmer; hypothetical protein 3609330 6971095 ECH74115_3896 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272122.1 3609211 R 444450 CDS YP_002272123.1 209396790 6968570 3615408..3616385 1 NC_011353.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3616385 6968570 ECH74115_3901 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272123.1 3615408 D 444450 CDS YP_002272124.1 209400455 6967721 3616405..3617673 1 NC_011353.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3617673 6967721 ECH74115_3902 Escherichia coli O157:H7 str. EC4115 hydroxyglutarate oxidase YP_002272124.1 3616405 D 444450 CDS YP_002272125.1 209399689 6971660 3617696..3619144 1 NC_011353.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3619144 gabD 6971660 gabD Escherichia coli O157:H7 str. EC4115 succinate-semialdehyde dehydrogenase I YP_002272125.1 3617696 D 444450 CDS YP_002272126.1 209398707 6970839 3619158..3620438 1 NC_011353.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3620438 gabT2 6970839 gabT2 Escherichia coli O157:H7 str. EC4115 4-aminobutyrate aminotransferase YP_002272126.1 3619158 D 444450 CDS YP_002272127.1 209400923 6969779 3620676..3622076 1 NC_011353.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773; gamma-aminobutyrate transporter 3622076 gabP 6969779 gabP Escherichia coli O157:H7 str. EC4115 gamma-aminobutyrate transporter YP_002272127.1 3620676 D 444450 CDS YP_002272128.1 209399433 6972160 3622097..3622759 1 NC_011353.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3622759 csiR 6972160 csiR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator CsiR YP_002272128.1 3622097 D 444450 CDS YP_002272129.1 209398904 6970561 complement(3622760..3623209) 1 NC_011353.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972; LysM domain/BON superfamily protein 3623209 6970561 ECH74115_3907 Escherichia coli O157:H7 str. EC4115 LysM domain/BON superfamily protein YP_002272129.1 3622760 R 444450 CDS YP_002272130.1 209397884 6969994 complement(3623293..3623451) 1 NC_011353.1 identified by match to protein family HMM PF01679; hypothetical protein 3623451 6969994 ECH74115_3908 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272130.1 3623293 R 444450 CDS YP_002272131.1 209397295 6968881 3623634..3623933 1 NC_011353.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 3623933 6968881 ECH74115_3909 Escherichia coli O157:H7 str. EC4115 ArsR family transcriptional regulator YP_002272131.1 3623634 D 444450 CDS YP_002272132.1 209399848 6968256 3623943..3624461 1 NC_011353.1 inner membrane protein 3624461 6968256 ECH74115_3910 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002272132.1 3623943 D 444450 CDS YP_002272133.1 209400130 6971005 complement(3624514..3624918) 1 NC_011353.1 identified by match to protein family HMM PF00816; DNA binding protein 3624918 stpA 6971005 stpA Escherichia coli O157:H7 str. EC4115 DNA binding protein YP_002272133.1 3624514 R 444450 CDS YP_002272134.1 209399639 6971315 3625586..3626035 1 NC_011353.1 identified by match to protein family HMM PF06610; hypothetical protein 3626035 6971315 ECH74115_3912 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272134.1 3625586 D 444450 CDS YP_002272135.1 209398919 6970784 complement(3626072..3626416) 1 NC_011353.1 identified by match to protein family HMM PF09400; hypothetical protein 3626416 6970784 ECH74115_3913 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272135.1 3626072 R 444450 CDS YP_002272136.1 209399748 6970011 3626568..3626897 1 NC_011353.1 identified by match to protein family HMM PF05957; hypothetical protein 3626897 6970011 ECH74115_3914 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272136.1 3626568 D 444450 CDS YP_002272137.1 209400513 6970904 complement(3627047..3628381) 1 NC_011353.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 3628381 6970904 ECH74115_3915 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002272137.1 3627047 R 444450 CDS YP_002272138.1 209396081 6971719 3628469..3628900 1 NC_011353.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; carboxymuconolactone decarboxylase family protein 3628900 6971719 ECH74115_3916 Escherichia coli O157:H7 str. EC4115 carboxymuconolactone decarboxylase family protein YP_002272138.1 3628469 D 444450 CDS YP_002272139.1 209396811 6966960 3629109..3629354 1 NC_011353.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194; glutaredoxin-like protein 3629354 nrdH 6966960 nrdH Escherichia coli O157:H7 str. EC4115 glutaredoxin-like protein YP_002272139.1 3629109 D 444450 CDS YP_002272140.1 209397592 6967743 3629351..3629761 1 NC_011353.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3629761 nrdI 6967743 nrdI Escherichia coli O157:H7 str. EC4115 ribonucleotide reductase stimulatory protein YP_002272140.1 3629351 D 444450 CDS YP_002272141.1 209398305 6968571 3629734..3631878 1 NC_011353.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3631878 nrdE 6968571 nrdE Escherichia coli O157:H7 str. EC4115 ribonucleotide-diphosphate reductase subunit alpha YP_002272141.1 3629734 D 444450 CDS YP_002272142.1 209400851 6969341 3631888..3632847 1 NC_011353.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3632847 nrdF 6969341 nrdF Escherichia coli O157:H7 str. EC4115 ribonucleotide-diphosphate reductase subunit beta YP_002272142.1 3631888 D 444450 CDS YP_002272143.1 209398437 6972082 3633203..3634405 1 NC_011353.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3634405 proV 6972082 proV Escherichia coli O157:H7 str. EC4115 glycine betaine transporter ATP-binding subunit YP_002272143.1 3633203 D 444450 CDS YP_002272144.1 209396362 6969489 3634398..3635462 1 NC_011353.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3635462 proW 6969489 proW Escherichia coli O157:H7 str. EC4115 glycine betaine transporter membrane protein YP_002272144.1 3634398 D 444450 CDS YP_002272145.1 209399990 6967264 3635519..3636511 1 NC_011353.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3636511 proX 6967264 proX Escherichia coli O157:H7 str. EC4115 glycine betaine transporter periplasmic subunit YP_002272145.1 3635519 D 444450 CDS YP_002272146.1 209399088 6971162 3636564..3636716 1 NC_011353.1 identified by glimmer; hypothetical protein 3636716 6971162 ECH74115_3924 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272146.1 3636564 D 444450 CDS YP_002272147.1 209398442 6970190 3636703..3637887 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 3637887 6970190 ECH74115_3925 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002272147.1 3636703 D 444450 CDS YP_002272148.1 209399046 6969494 3638056..3638748 1 NC_011353.1 identified by match to protein family HMM PF03591; transporter branched chain amino acid exporter (LIV-E) family 3638748 6969494 ECH74115_3926 Escherichia coli O157:H7 str. EC4115 transporter branched chain amino acid exporter (LIV-E) family YP_002272148.1 3638056 D 444450 CDS YP_002272149.1 209398555 6970148 3638738..3639073 1 NC_011353.1 hypothetical protein 3639073 6970148 ECH74115_3927 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272149.1 3638738 D 444450 CDS YP_002272150.1 209400865 6969615 3639164..3639694 1 NC_011353.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3639694 mprA 6969615 mprA Escherichia coli O157:H7 str. EC4115 transcriptional repressor MprA YP_002272150.1 3639164 D 444450 CDS YP_002272151.1 209399778 6972096 complement(3639722..3639856) 1 NC_011353.1 identified by glimmer; hypothetical protein 3639856 6972096 ECH74115_3929 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272151.1 3639722 R 444450 CDS YP_002272152.1 209396692 6970935 3639809..3640993 1 NC_011353.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998; multidrug resistance protein A 3640993 emrA 6970935 emrA Escherichia coli O157:H7 str. EC4115 multidrug resistance protein A YP_002272152.1 3639809 D 444450 CDS YP_002272153.1 209396264 6967614 3641010..3642548 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; multidrug resistance protein B 3642548 emrB 6967614 emrB Escherichia coli O157:H7 str. EC4115 multidrug resistance protein B YP_002272153.1 3641010 D 444450 CDS YP_002272154.1 209398571 6967157 complement(3642612..3643127) 1 NC_011353.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 3643127 luxS 6967157 luxS Escherichia coli O157:H7 str. EC4115 S-ribosylhomocysteinase YP_002272154.1 3642612 R 444450 CDS YP_002272155.1 209397887 6972324 complement(3643277..3644833) 1 NC_011353.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 3644833 gshA 6972324 gshA Escherichia coli O157:H7 str. EC4115 glutamate--cysteine ligase YP_002272155.1 3643277 R 444450 CDS YP_002272156.1 209396879 6968884 complement(3644906..3645334) 1 NC_011353.1 hypothetical protein 3645334 6968884 ECH74115_3935 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272156.1 3644906 R 444450 CDS YP_002272157.1 209396302 6967816 complement(3645331..3645897) 1 NC_011353.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 3645897 6967816 ECH74115_3936 Escherichia coli O157:H7 str. EC4115 fructose-1-phosphatase YP_002272157.1 3645331 R 444450 CDS YP_002272158.1 209399950 6972396 complement(3647125..3647310) 1 NC_011353.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 3647310 csrA 6972396 csrA Escherichia coli O157:H7 str. EC4115 carbon storage regulator YP_002272158.1 3647125 R 444450 CDS YP_002272159.1 209399016 6971118 3647420..3647536 1 NC_011353.1 identified by glimmer; hypothetical protein 3647536 6971118 ECH74115_3943 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272159.1 3647420 D 444450 CDS YP_002272160.1 209398791 6970116 complement(3647545..3650175) 1 NC_011353.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 3650175 alaS 6970116 alaS Escherichia coli O157:H7 str. EC4115 alanyl-tRNA synthetase YP_002272160.1 3647545 R 444450 CDS YP_002272161.1 209397890 6969869 complement(3650303..3650803) 1 NC_011353.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3650803 recX 6969869 recX Escherichia coli O157:H7 str. EC4115 recombination regulator RecX YP_002272161.1 3650303 R 444450 CDS YP_002272162.1 209397319 6968887 complement(3650871..3651932) 1 NC_011353.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 3651932 recA 6968887 recA Escherichia coli O157:H7 str. EC4115 recombinase A YP_002272162.1 3650871 R 444450 CDS YP_002272163.1 209396597 6968281 complement(3652012..3652509) 1 NC_011353.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A 3652509 6968281 ECH74115_3947 Escherichia coli O157:H7 str. EC4115 competence damage-inducible protein A YP_002272163.1 3652012 R 444450 CDS YP_002272164.1 209399525 6967514 complement(3652654..3653739) 1 NC_011353.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 3653739 mltB 6967514 mltB Escherichia coli O157:H7 str. EC4115 murein hydrolase B YP_002272164.1 3652654 R 444450 CDS YP_002272165.1 209399761 6970661 complement(3653870..3654007) 1 NC_011353.1 identified by glimmer; hypothetical protein 3654007 6970661 ECH74115_3949 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272165.1 3653870 R 444450 CDS YP_002272166.1 209400572 6967170 3655525..3655896 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3655896 srlB 6967170 srlB Escherichia coli O157:H7 str. EC4115 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_002272166.1 3655525 D 444450 CDS YP_002272167.1 209400828 6971782 3655900..3656679 1 NC_011353.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3656679 srlD 6971782 srlD Escherichia coli O157:H7 str. EC4115 sorbitol-6-phosphate dehydrogenase YP_002272167.1 3655900 D 444450 CDS YP_002272168.1 209399048 6972056 3656785..3657144 1 NC_011353.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3657144 gutM 6972056 gutM Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator GutM YP_002272168.1 3656785 D 444450 CDS YP_002272169.1 209398484 6970150 3657211..3657984 1 NC_011353.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3657984 srlR 6970150 srlR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor SrlR YP_002272169.1 3657211 D 444450 CDS YP_002272170.1 209396393 6969541 3657977..3658942 1 NC_011353.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3658942 gutQ 6969541 gutQ Escherichia coli O157:H7 str. EC4115 D-arabinose 5-phosphate isomerase YP_002272170.1 3657977 D 444450 CDS YP_002272171.1 209399708 6967299 complement(3658939..3660453) 1 NC_011353.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 3660453 norR 6967299 norR Escherichia coli O157:H7 str. EC4115 anaerobic nitric oxide reductase transcriptional regulator YP_002272171.1 3658939 R 444450 CDS YP_002272172.1 209399567 6970859 3660640..3662079 1 NC_011353.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3662079 norV 6970859 norV Escherichia coli O157:H7 str. EC4115 anaerobic nitric oxide reductase flavorubredoxin YP_002272172.1 3660640 D 444450 CDS YP_002272173.1 209398985 6970705 3662076..3663209 1 NC_011353.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3663209 norW 6970705 norW Escherichia coli O157:H7 str. EC4115 nitric oxide reductase YP_002272173.1 3662076 D 444450 CDS YP_002272174.1 209397726 6970084 complement(3663337..3665637) 1 NC_011353.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143; carbamoyltransferase HypF 3665637 hypF 6970084 hypF Escherichia coli O157:H7 str. EC4115 carbamoyltransferase HypF YP_002272174.1 3663337 R 444450 CDS YP_002272175.1 209397141 6968711 complement(3665742..3666269) 1 NC_011353.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 3666269 6968711 ECH74115_3963 Escherichia coli O157:H7 str. EC4115 electron transport protein HydN YP_002272175.1 3665742 R 444450 CDS YP_002272176.1 209397110 6968092 complement(3666247..3666414) 1 NC_011353.1 identified by glimmer; hypothetical protein 3666414 6968092 ECH74115_3964 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272176.1 3666247 R 444450 CDS YP_002272177.1 209396524 6968059 complement(3666418..3667470) 1 NC_011353.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator AscG 3667470 ascG 6968059 ascG Escherichia coli O157:H7 str. EC4115 transcriptional regulator AscG YP_002272177.1 3666418 R 444450 CDS YP_002272178.1 209396010 6967437 3667688..3669145 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 3669145 ascF 6967437 ascF Escherichia coli O157:H7 str. EC4115 PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_002272178.1 3667688 D 444450 CDS YP_002272179.1 209400081 6966883 3669154..3670578 1 NC_011353.1 identified by match to protein family HMM PF00232; cryptic 6-phospho-beta-glucosidase 3670578 ascB 6966883 ascB Escherichia coli O157:H7 str. EC4115 cryptic 6-phospho-beta-glucosidase YP_002272179.1 3669154 D 444450 CDS YP_002272180.1 209400052 6971260 complement(3670702..3671172) 1 NC_011353.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3671172 hycI 6971260 hycI Escherichia coli O157:H7 str. EC4115 hydrogenase 3 maturation protease YP_002272180.1 3670702 R 444450 CDS YP_002272181.1 209399984 6971230 complement(3671165..3671575) 1 NC_011353.1 identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein 3671575 6971230 ECH74115_3969 Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase maturation protein YP_002272181.1 3671165 R 444450 CDS YP_002272182.1 209396735 6971156 complement(3671572..3672339) 1 NC_011353.1 identified by match to protein family HMM PF01058; formate hydrogenlyase subunit G 3672339 hycG 6971156 hycG Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase subunit G YP_002272182.1 3671572 R 444450 CDS YP_002272183.1 209396172 6967661 complement(3672339..3672881) 1 NC_011353.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3672881 hycF 6967661 hycF Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase complex iron-sulfur subunit YP_002272183.1 3672339 R 444450 CDS YP_002272184.1 209400571 6967056 complement(3672891..3674621) 1 NC_011353.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346; formate hydrogenlyase subunit E 3674621 hycE 6967056 hycE Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase subunit E YP_002272184.1 3672891 R 444450 CDS YP_002272185.1 209399858 6971781 complement(3674618..3675541) 1 NC_011353.1 identified by match to protein family HMM PF00146; formate hydrogenlyase subunit D 3675541 hycD 6971781 hycD Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase subunit D YP_002272185.1 3674618 R 444450 CDS YP_002272186.1 209399973 6971017 complement(3675544..3677370) 1 NC_011353.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3677370 hycC 6971017 hycC Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase subunit 3 YP_002272186.1 3675544 R 444450 CDS YP_002272187.1 209399068 6971145 complement(3677367..3677978) 1 NC_011353.1 identified by match to protein family HMM PF00037; formate hydrogenlyase subunit B 3677978 hycB 6971145 hycB Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase subunit B YP_002272187.1 3677367 R 444450 CDS YP_002272188.1 209398474 6970170 complement(3678103..3678564) 1 NC_011353.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3678564 hycA 6970170 hycA Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase regulatory protein HycA YP_002272188.1 3678103 R 444450 CDS YP_002272189.1 209397553 6969530 complement(3678598..3678735) 1 NC_011353.1 identified by glimmer; hypothetical protein 3678735 6969530 ECH74115_3977 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272189.1 3678598 R 444450 CDS YP_002272190.1 209397638 6968528 3678764..3679126 1 NC_011353.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3679126 hypA 6968528 hypA Escherichia coli O157:H7 str. EC4115 hydrogenase nickel incorporation protein YP_002272190.1 3678764 D 444450 CDS YP_002272191.1 209397040 6968621 3679130..3680002 1 NC_011353.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3680002 hypB 6968621 hypB Escherichia coli O157:H7 str. EC4115 hydrogenase nickel incorporation protein HypB YP_002272191.1 3679130 D 444450 CDS YP_002272192.1 209398163 6967985 3679993..3680265 1 NC_011353.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3680265 hypC2 6967985 hypC2 Escherichia coli O157:H7 str. EC4115 hydrogenase assembly chaperone YP_002272192.1 3679993 D 444450 CDS YP_002272193.1 209396571 6969187 3680265..3681386 1 NC_011353.1 identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075; hydrogenase expression/formation protein HypD 3681386 hypD 6969187 hypD Escherichia coli O157:H7 str. EC4115 hydrogenase expression/formation protein HypD YP_002272193.1 3680265 D 444450 CDS YP_002272194.1 209396976 6967485 3681383..3682393 1 NC_011353.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124; hydrogenase expression/formation protein HypE 3682393 hypE 6967485 hypE Escherichia coli O157:H7 str. EC4115 hydrogenase expression/formation protein HypE YP_002272194.1 3681383 D 444450 CDS YP_002272195.1 209396082 6967917 3682467..3684545 1 NC_011353.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; formate hydrogenlyase transcriptional activator 3684545 fhlA 6967917 fhlA Escherichia coli O157:H7 str. EC4115 formate hydrogenlyase transcriptional activator YP_002272195.1 3682467 D 444450 CDS YP_002272196.1 209400476 6966961 complement(3684582..3684935) 1 NC_011353.1 hypothetical protein 3684935 6966961 ECH74115_3984 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272196.1 3684582 R 444450 CDS YP_002272197.1 209400235 6971681 complement(3685012..3685146) 1 NC_011353.1 identified by glimmer; hypothetical protein 3685146 6971681 ECH74115_3985 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272197.1 3685012 R 444450 CDS YP_002272198.1 209399182 6971425 3685222..3687783 1 NC_011353.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3687783 mutS 6971425 mutS Escherichia coli O157:H7 str. EC4115 DNA mismatch repair protein MutS YP_002272198.1 3685222 D 444450 CDS YP_002272199.1 209398599 6970290 3687889..3688545 1 NC_011353.1 identified by match to protein family HMM PF00149; serine/threonine-specific protein phosphatase 2 3688545 pphB 6970290 pphB Escherichia coli O157:H7 str. EC4115 serine/threonine-specific protein phosphatase 2 YP_002272199.1 3687889 D 444450 CDS YP_002272200.1 209396541 6969662 complement(3688586..3688822) 1 NC_011353.1 4-hydroxybenzoate decarboxylase subunit D 3688822 kpdD 6969662 kpdD Escherichia coli O157:H7 str. EC4115 4-hydroxybenzoate decarboxylase subunit D YP_002272200.1 3688586 R 444450 CDS YP_002272201.1 209395965 6967454 complement(3688833..3690260) 1 NC_011353.1 identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148; 4-hydroxybenzoate decarboxylase subunit C 3690260 kpdC 6967454 kpdC Escherichia coli O157:H7 str. EC4115 4-hydroxybenzoate decarboxylase subunit C YP_002272201.1 3688833 R 444450 CDS YP_002272202.1 209397606 6966833 complement(3690260..3690853) 1 NC_011353.1 identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421; 4-hydroxybenzoate decarboxylase subunit B 3690853 kpdB 6966833 kpdB Escherichia coli O157:H7 str. EC4115 4-hydroxybenzoate decarboxylase subunit B YP_002272202.1 3690260 R 444450 CDS YP_002272203.1 209396844 6968587 3691000..3691407 1 NC_011353.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3691407 6968587 ECH74115_3991 Escherichia coli O157:H7 str. EC4115 MarR family transcriptional regulator YP_002272203.1 3691000 D 444450 CDS YP_002272204.1 209395891 6967777 complement(3691527..3692519) 1 NC_011353.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3692519 rpoS 6967777 rpoS Escherichia coli O157:H7 str. EC4115 RNA polymerase sigma factor RpoS YP_002272204.1 3691527 R 444450 CDS YP_002272205.1 209400494 6966757 complement(3692582..3693673) 1 NC_011353.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3693673 nlpD 6966757 nlpD Escherichia coli O157:H7 str. EC4115 lipoprotein NlpD YP_002272205.1 3692582 R 444450 CDS YP_002272206.1 209399278 6971699 complement(3693813..3694439) 1 NC_011353.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3694439 pcm 6971699 pcm Escherichia coli O157:H7 str. EC4115 protein-L-isoaspartate O-methyltransferase YP_002272206.1 3693813 R 444450 CDS YP_002272207.1 209398515 6970394 complement(3694433..3695194) 1 NC_011353.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3695194 surE 6970394 surE Escherichia coli O157:H7 str. EC4115 stationary phase survival protein SurE YP_002272207.1 3694433 R 444450 CDS YP_002272208.1 209398920 6969573 complement(3695175..3696224) 1 NC_011353.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3696224 truD 6969573 truD Escherichia coli O157:H7 str. EC4115 tRNA pseudouridine synthase D YP_002272208.1 3695175 R 444450 CDS YP_002272209.1 209398155 6970012 complement(3696221..3696700) 1 NC_011353.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 3696700 ispF 6970012 ispF Escherichia coli O157:H7 str. EC4115 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase YP_002272209.1 3696221 R 444450 CDS YP_002272210.1 209397849 6969179 complement(3696700..3697410) 1 NC_011353.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3697410 ispD 6969179 ispD Escherichia coli O157:H7 str. EC4115 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002272210.1 3696700 R 444450 CDS YP_002272211.1 209396991 6968841 complement(3697429..3697740) 1 NC_011353.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3697740 ftsB 6968841 ftsB Escherichia coli O157:H7 str. EC4115 cell division protein FtsB YP_002272211.1 3697429 R 444450 CDS YP_002272212.1 209400636 6968161 complement(3697934..3698257) 1 NC_011353.1 hypothetical protein 3698257 6968161 ECH74115_4001 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272212.1 3697934 R 444450 CDS YP_002272213.1 209399413 6971850 complement(3698307..3698912) 1 NC_011353.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3698912 cysC 6971850 cysC Escherichia coli O157:H7 str. EC4115 adenylylsulfate kinase YP_002272213.1 3698307 R 444450 CDS YP_002272214.1 209400153 6970539 complement(3698912..3700339) 1 NC_011353.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3700339 cysN 6970539 cysN Escherichia coli O157:H7 str. EC4115 sulfate adenylyltransferase subunit 1 YP_002272214.1 3698912 R 444450 CDS YP_002272215.1 209400969 6971339 complement(3700341..3701249) 1 NC_011353.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3701249 cysD 6971339 cysD Escherichia coli O157:H7 str. EC4115 sulfate adenylyltransferase subunit 2 YP_002272215.1 3700341 R 444450 CDS YP_002272216.1 209395718 6972209 3701501..3702538 1 NC_011353.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 3702538 iap 6972209 iap Escherichia coli O157:H7 str. EC4115 alkaline phosphatase isozyme conversion aminopeptidase YP_002272216.1 3701501 D 444450 CDS YP_002272217.1 209396488 6966573 3702775..3702891 1 NC_011353.1 identified by glimmer; hypothetical protein 3702891 6966573 ECH74115_4006 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272217.1 3702775 D 444450 CDS YP_002272218.1 209397199 6967400 complement(3702928..3703221) 1 NC_011353.1 identified by match to protein family HMM PF09707; match to protein family HMM TIGR01873; hypothetical protein 3703221 6967400 ECH74115_4007 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272218.1 3702928 R 444450 CDS YP_002272219.1 209397933 6968155 complement(3703218..3704141) 1 NC_011353.1 identified by match to protein family HMM TIGR00287; match to protein family HMM TIGR03638; CRISPR-associated protein Cas1 3704141 cas1 6968155 cas1 Escherichia coli O157:H7 str. EC4115 CRISPR-associated protein Cas1 YP_002272219.1 3703218 R 444450 CDS YP_002272220.1 209399506 6968934 complement(3704138..3704788) 1 NC_011353.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907; CRISPR-associated protein, Cse3 family 3704788 cse3 6968934 cse3 Escherichia coli O157:H7 str. EC4115 CRISPR-associated protein, Cse3 family YP_002272220.1 3704138 R 444450 CDS YP_002272221.1 209396791 6970641 complement(3704770..3705516) 1 NC_011353.1 identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593; CRISPR-associated protein Cas5 3705516 cas5e 6970641 cas5e Escherichia coli O157:H7 str. EC4115 CRISPR-associated protein Cas5 YP_002272221.1 3704770 R 444450 CDS YP_002272222.1 209399904 6967722 complement(3705527..3706582) 1 NC_011353.1 identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869; CRISPR-associated protein, Cse4 family 3706582 cse4 6967722 cse4 Escherichia coli O157:H7 str. EC4115 CRISPR-associated protein, Cse4 family YP_002272222.1 3705527 R 444450 CDS YP_002272223.1 209397969 6971068 complement(3706594..3707130) 1 NC_011353.1 identified by match to protein family HMM PF09485; match to protein family HMM TIGR02548; Cse2 family CRISPR-associated protein 3707130 cse2 6971068 cse2 Escherichia coli O157:H7 str. EC4115 Cse2 family CRISPR-associated protein YP_002272223.1 3706594 R 444450 CDS YP_002272224.1 209395699 6968976 complement(3707127..3708689) 1 NC_011353.1 identified by match to protein family HMM PF09481; match to protein family HMM TIGR02547; Cse1 family CRISPR-associated protein 3708689 cse1 6968976 cse1 Escherichia coli O157:H7 str. EC4115 Cse1 family CRISPR-associated protein YP_002272224.1 3707127 R 444450 CDS YP_002272225.1 209398890 6966553 complement(3708787..3711486) 1 NC_011353.1 identified by match to protein family HMM TIGR01587; CRISPR-associated helicase Cas3 3711486 cas3 6966553 cas3 Escherichia coli O157:H7 str. EC4115 CRISPR-associated helicase Cas3 YP_002272225.1 3708787 R 444450 CDS YP_002272226.1 209399654 6972254 complement(3712094..3712828) 1 NC_011353.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3712828 cysH 6972254 cysH Escherichia coli O157:H7 str. EC4115 phosphoadenosine phosphosulfate reductase YP_002272226.1 3712094 R 444450 CDS YP_002272227.1 209400070 6970800 complement(3712902..3714614) 1 NC_011353.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3714614 cysI 6970800 cysI Escherichia coli O157:H7 str. EC4115 sulfite reductase subunit beta YP_002272227.1 3712902 R 444450 CDS YP_002272228.1 209400763 6971249 complement(3714614..3716413) 1 NC_011353.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3716413 cysJ 6971249 cysJ Escherichia coli O157:H7 str. EC4115 sulfite reductase subunit alpha YP_002272228.1 3714614 R 444450 CDS YP_002272229.1 209396000 6971988 complement(3716626..3716739) 1 NC_011353.1 identified by glimmer; hypothetical protein 3716739 6971988 ECH74115_4019 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272229.1 3716626 R 444450 CDS YP_002272230.1 209396419 6966872 3716732..3717094 1 NC_011353.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367; queuosine biosynthesis protein QueD 3717094 queD 6966872 queD Escherichia coli O157:H7 str. EC4115 queuosine biosynthesis protein QueD YP_002272230.1 3716732 D 444450 CDS YP_002272231.1 209397050 6967326 3717172..3718443 1 NC_011353.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 3718443 6967326 ECH74115_4021 Escherichia coli O157:H7 str. EC4115 pyridine nucleotide-disulfide oxidoreductase family protein YP_002272231.1 3717172 D 444450 CDS YP_002272232.1 209398115 6967996 3718434..3718694 1 NC_011353.1 ferredoxin 3718694 6967996 ECH74115_4022 Escherichia coli O157:H7 str. EC4115 ferredoxin YP_002272232.1 3718434 D 444450 CDS YP_002272233.1 209396212 6969134 3718711..3719286 1 NC_011353.1 identified by match to protein family HMM PF04309; glycerol-3-phosphate responsive antiterminator 3719286 6969134 ECH74115_4023 Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate responsive antiterminator YP_002272233.1 3718711 D 444450 CDS YP_002272234.1 209400482 6967714 complement(3720291..3721070) 1 NC_011353.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein 3721070 6967714 ECH74115_4026 Escherichia coli O157:H7 str. EC4115 electron transfer flavoprotein YP_002272234.1 3720291 R 444450 CDS YP_002272235.1 209399257 6969393 complement(3722478..3723932) 1 NC_011353.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD binding domain-containing protein 3723932 6969393 ECH74115_4029 Escherichia coli O157:H7 str. EC4115 FAD binding domain-containing protein YP_002272235.1 3722478 R 444450 CDS YP_002272236.1 209397522 6970371 complement(3724002..3724787) 1 NC_011353.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 3724787 6970371 ECH74115_4030 Escherichia coli O157:H7 str. EC4115 short chain dehydrogenase/reductase family oxidoreductase YP_002272236.1 3724002 R 444450 CDS YP_002272237.1 209400723 6968495 3725106..3726383 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 3726383 6968495 ECH74115_4031 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002272237.1 3725106 D 444450 CDS YP_002272238.1 209399162 6971947 3726410..3727888 1 NC_011353.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; carbohydrate kinase, FGGY family protein 3727888 6971947 ECH74115_4032 Escherichia coli O157:H7 str. EC4115 carbohydrate kinase, FGGY family protein YP_002272238.1 3726410 D 444450 CDS YP_002272239.1 209398503 6970270 complement(3728952..3729623) 1 NC_011353.1 hypothetical protein 3729623 6970270 ECH74115_4033 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272239.1 3728952 R 444450 CDS YP_002272240.1 209398290 6969561 3729904..3730398 1 NC_011353.1 identified by match to protein family HMM PF04011; LemA family protein 3730398 6969561 ECH74115_4034 Escherichia coli O157:H7 str. EC4115 LemA family protein YP_002272240.1 3729904 D 444450 CDS YP_002272241.1 209396734 6967988 3731166..3731318 1 NC_011353.1 hypothetical protein 3731318 6967988 ECH74115_4036 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272241.1 3731166 D 444450 CDS YP_002272242.1 209396155 6967660 3731320..3732468 1 NC_011353.1 identified by match to protein family HMM PF04536; hypothetical protein 3732468 6967660 ECH74115_4037 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272242.1 3731320 D 444450 CDS YP_002272243.1 209399772 6967038 3732474..3733379 1 NC_011353.1 identified by match to protein family HMM PF04536; hypothetical protein 3733379 6967038 ECH74115_4038 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272243.1 3732474 D 444450 CDS YP_002272244.1 209400352 6970928 complement(3733439..3734737) 1 NC_011353.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3734737 eno 6970928 eno Escherichia coli O157:H7 str. EC4115 phosphopyruvate hydratase YP_002272244.1 3733439 R 444450 CDS YP_002272245.1 209398762 6971550 complement(3734825..3736462) 1 NC_011353.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3736462 pyrG 6971550 pyrG Escherichia coli O157:H7 str. EC4115 CTP synthetase YP_002272245.1 3734825 R 444450 CDS YP_002272246.1 209400744 6969840 complement(3736690..3737481) 1 NC_011353.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 3737481 mazG 6969840 mazG Escherichia coli O157:H7 str. EC4115 nucleoside triphosphate pyrophosphohydrolase YP_002272246.1 3736690 R 444450 CDS YP_002272247.1 209400651 6971969 complement(3737552..3737887) 1 NC_011353.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 3737887 chpA 6971969 chpA Escherichia coli O157:H7 str. EC4115 toxin ChpA YP_002272247.1 3737552 R 444450 CDS YP_002272248.1 209400819 6971867 complement(3737887..3738135) 1 NC_011353.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 3738135 chpR 6971867 chpR Escherichia coli O157:H7 str. EC4115 antitoxin MazE YP_002272248.1 3737887 R 444450 CDS YP_002272249.1 209400075 6972047 complement(3738213..3740447) 1 NC_011353.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3740447 relA 6972047 relA Escherichia coli O157:H7 str. EC4115 GDP/GTP pyrophosphokinase YP_002272249.1 3738213 R 444450 CDS YP_002272250.1 209399664 6971254 complement(3740495..3741796) 1 NC_011353.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3741796 rumA 6971254 rumA Escherichia coli O157:H7 str. EC4115 23S rRNA 5-methyluridine methyltransferase YP_002272250.1 3740495 R 444450 CDS YP_002272251.1 209398921 6970811 3741853..3744609 1 NC_011353.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3744609 barA 6970811 barA Escherichia coli O157:H7 str. EC4115 hybrid sensory histidine kinase BarA YP_002272251.1 3741853 D 444450 CDS YP_002272252.1 209397778 6970013 complement(3744842..3746182) 1 NC_011353.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247; glucarate dehydratase 3746182 6970013 ECH74115_4047 Escherichia coli O157:H7 str. EC4115 glucarate dehydratase YP_002272252.1 3744842 R 444450 CDS YP_002272253.1 209400750 6967524 complement(3747545..3748897) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; glucarate permease 3748897 gudP 6967524 gudP Escherichia coli O157:H7 str. EC4115 glucarate permease YP_002272253.1 3747545 R 444450 CDS YP_002272254.1 209398965 6971975 complement(3748992..3749117) 1 NC_011353.1 identified by glimmer; hypothetical protein 3749117 6971975 ECH74115_4051 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272254.1 3748992 R 444450 CDS YP_002272255.1 209398247 6970060 3749111..3749239 1 NC_011353.1 identified by glimmer; hypothetical protein 3749239 6970060 ECH74115_4052 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272255.1 3749111 D 444450 CDS YP_002272256.1 209397840 6969279 complement(3749332..3749781) 1 NC_011353.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3749781 6969279 ECH74115_4053 Escherichia coli O157:H7 str. EC4115 flavodoxin YP_002272256.1 3749332 R 444450 CDS YP_002272257.1 209397015 6968832 complement(3749799..3750581) 1 NC_011353.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3750581 truC 6968832 truC Escherichia coli O157:H7 str. EC4115 tRNA pseudouridine synthase C YP_002272257.1 3749799 R 444450 CDS YP_002272258.1 209395886 6967959 complement(3750581..3750910) 1 NC_011353.1 identified by match to protein family HMM PF04287; hypothetical protein 3750910 6967959 ECH74115_4055 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272258.1 3750581 R 444450 CDS YP_002272259.1 209400675 6972308 complement(3751532..3752077) 1 NC_011353.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3752077 6972308 ECH74115_4057 Escherichia coli O157:H7 str. EC4115 SecY interacting protein Syd YP_002272259.1 3751532 R 444450 CDS YP_002272260.1 209399818 6971894 3752145..3752993 1 NC_011353.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3752993 queF 6971894 queF Escherichia coli O157:H7 str. EC4115 7-cyano-7-deazaguanine reductase YP_002272260.1 3752145 D 444450 CDS YP_002272261.1 209399193 6970975 3753105..3754469 1 NC_011353.1 identified by match to protein family HMM PF03641; hypothetical protein 3754469 6970975 ECH74115_4059 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272261.1 3753105 D 444450 CDS YP_002272262.1 209397478 6970301 3755026..3756315 1 NC_011353.1 identified by match to protein family HMM TIGR00814; serine transporter family protein 3756315 6970301 ECH74115_4060 Escherichia coli O157:H7 str. EC4115 serine transporter family protein YP_002272262.1 3755026 D 444450 CDS YP_002272263.1 209396781 6968449 3756373..3757740 1 NC_011353.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine ammonia-lyase 2 3757740 sdaB 6968449 sdaB Escherichia coli O157:H7 str. EC4115 L-serine ammonia-lyase 2 YP_002272263.1 3756373 D 444450 CDS YP_002272264.1 209398738 6967711 3757852..3758607 1 NC_011353.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3758607 xni 6967711 xni Escherichia coli O157:H7 str. EC4115 exonuclease IX YP_002272264.1 3757852 D 444450 CDS YP_002272265.1 209399643 6969814 complement(3758662..3759813) 1 NC_011353.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638; L-1,2-propanediol oxidoreductase 3759813 fucO 6969814 fucO Escherichia coli O157:H7 str. EC4115 L-1,2-propanediol oxidoreductase YP_002272265.1 3758662 R 444450 CDS YP_002272266.1 209398432 6970788 complement(3759838..3760485) 1 NC_011353.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3760485 fucA 6970788 fucA Escherichia coli O157:H7 str. EC4115 L-fuculose phosphate aldolase YP_002272266.1 3759838 R 444450 CDS YP_002272267.1 209399079 6969480 3761032..3762348 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885; L-fucose transporter 3762348 fucP 6969480 fucP Escherichia coli O157:H7 str. EC4115 L-fucose transporter YP_002272267.1 3761032 D 444450 CDS YP_002272268.1 209399932 6970181 3762381..3764156 1 NC_011353.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3764156 fucI 6970181 fucI Escherichia coli O157:H7 str. EC4115 L-fucose isomerase YP_002272268.1 3762381 D 444450 CDS YP_002272269.1 209400521 6971097 3764235..3765683 1 NC_011353.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628; L-fuculokinase 3765683 fucK 6971097 fucK Escherichia coli O157:H7 str. EC4115 L-fuculokinase YP_002272269.1 3764235 D 444450 CDS YP_002272270.1 209396564 6971728 3765685..3766107 1 NC_011353.1 identified by match to protein family HMM PF05025; fucose operon protein FucU 3766107 fucU 6971728 fucU Escherichia coli O157:H7 str. EC4115 fucose operon protein FucU YP_002272270.1 3765685 D 444450 CDS YP_002272271.1 209397462 6967478 3766165..3766896 1 NC_011353.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3766896 fucR 6967478 fucR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator FucR YP_002272271.1 3766165 D 444450 CDS YP_002272272.1 209398340 6968433 complement(3766940..3768040) 1 NC_011353.1 RNA 2'-O-ribose methyltransferase 3768040 6968433 ECH74115_4070 Escherichia coli O157:H7 str. EC4115 RNA 2'-O-ribose methyltransferase YP_002272272.1 3766940 R 444450 CDS YP_002272273.1 209398748 6969380 complement(3768033..3768428) 1 NC_011353.1 identified by match to protein family HMM PF04241; hypothetical protein 3768428 6969380 ECH74115_4071 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272273.1 3768033 R 444450 CDS YP_002272274.1 209400092 6969824 complement(3768447..3769364) 1 NC_011353.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3769364 gcvA 6969824 gcvA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator GcvA YP_002272274.1 3768447 R 444450 CDS YP_002272275.1 209400704 6972259 complement(3769715..3769942) 1 NC_011353.1 identified by match to protein family HMM PF06004; lipoprotein 3769942 6972259 ECH74115_4074 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002272275.1 3769715 R 444450 CDS YP_002272276.1 209397968 6971927 3770134..3771339 1 NC_011353.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392; cysteine sulfinate desulfinase 3771339 csdA 6971927 csdA Escherichia coli O157:H7 str. EC4115 cysteine sulfinate desulfinase YP_002272276.1 3770134 D 444450 CDS YP_002272277.1 209395840 6968974 3771339..3771782 1 NC_011353.1 identified by match to protein family HMM PF02657; match to protein family HMM TIGR03391; cysteine desulfuration protein CsdE 3771782 csdE 6968974 csdE Escherichia coli O157:H7 str. EC4115 cysteine desulfuration protein CsdE YP_002272277.1 3771339 D 444450 CDS YP_002272278.1 209397158 6966697 complement(3771833..3772633) 1 NC_011353.1 identified by match to protein family HMM PF00899; ThiF family protein 3772633 6966697 ECH74115_4077 Escherichia coli O157:H7 str. EC4115 ThiF family protein YP_002272278.1 3771833 R 444450 CDS YP_002272279.1 209397699 6968110 complement(3772878..3773945) 1 NC_011353.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3773945 mltA 6968110 mltA Escherichia coli O157:H7 str. EC4115 murein transglycosylase A YP_002272279.1 3772878 R 444450 CDS YP_002272280.1 209398948 6972414 complement(3774554..3775807) 1 NC_011353.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-L-alanine amidase AmiC 3775807 amiC 6972414 amiC Escherichia coli O157:H7 str. EC4115 N-acetylmuramoyl-L-alanine amidase AmiC YP_002272280.1 3774554 R 444450 CDS YP_002272281.1 209399392 6970042 3776039..3777370 1 NC_011353.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3777370 argA 6970042 argA Escherichia coli O157:H7 str. EC4115 N-acetylglutamate synthase YP_002272281.1 3776039 D 444450 CDS YP_002272282.1 209397729 6970517 complement(3777432..3779258) 1 NC_011353.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3779258 recD 6970517 recD Escherichia coli O157:H7 str. EC4115 exonuclease V subunit alpha YP_002272282.1 3777432 R 444450 CDS YP_002272283.1 209398198 6968714 complement(3779258..3782800) 1 NC_011353.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3782800 recB 6968714 recB Escherichia coli O157:H7 str. EC4115 exonuclease V subunit beta YP_002272283.1 3779258 R 444450 CDS YP_002272284.1 209397695 6969226 complement(3782793..3785681) 1 NC_011353.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; protease III 3785681 ptrA 6969226 ptrA Escherichia coli O157:H7 str. EC4115 protease III YP_002272284.1 3782793 R 444450 CDS YP_002272285.1 209396729 6968678 complement(3785857..3789225) 1 NC_011353.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3789225 recC 6968678 recC Escherichia coli O157:H7 str. EC4115 exonuclease V subunit gamma YP_002272285.1 3785857 R 444450 CDS YP_002272286.1 209396653 6967655 complement(3789238..3789561) 1 NC_011353.1 identified by match to protein family HMM TIGR02532; hypothetical protein 3789561 ppdC 6967655 ppdC Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272286.1 3789238 R 444450 CDS YP_002272287.1 209397231 6967573 complement(3789546..3789953) 1 NC_011353.1 hypothetical protein 3789953 6967573 ECH74115_4089 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272287.1 3789546 R 444450 CDS YP_002272288.1 209397816 6968189 complement(3789950..3790513) 1 NC_011353.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein 3790513 ppdB 6968189 ppdB Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272288.1 3789950 R 444450 CDS YP_002272289.1 209399023 6968807 complement(3790504..3790974) 1 NC_011353.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein 3790974 ppdA 6968807 ppdA Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272289.1 3790504 R 444450 CDS YP_002272290.1 209400848 6968581 complement(3791158..3791952) 1 NC_011353.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3791952 thyA 6968581 thyA Escherichia coli O157:H7 str. EC4115 thymidylate synthase YP_002272290.1 3791158 R 444450 CDS YP_002272291.1 209398771 6972079 complement(3791959..3792834) 1 NC_011353.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3792834 lgt 6972079 lgt Escherichia coli O157:H7 str. EC4115 prolipoprotein diacylglyceryl transferase YP_002272291.1 3791959 R 444450 CDS YP_002272292.1 209400141 6969849 complement(3792985..3795231) 1 NC_011353.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3795231 ptsP 6969849 ptsP Escherichia coli O157:H7 str. EC4115 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_002272292.1 3792985 R 444450 CDS YP_002272293.1 209397601 6971327 complement(3795244..3795774) 1 NC_011353.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3795774 nudH 6971327 nudH Escherichia coli O157:H7 str. EC4115 dinucleoside polyphosphate hydrolase YP_002272293.1 3795244 R 444450 CDS YP_002272294.1 209400789 6968580 3796219..3796380 1 NC_011353.1 identified by glimmer; hypothetical protein 3796380 6968580 ECH74115_4097 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272294.1 3796219 D 444450 CDS YP_002272295.1 209400627 6972015 3796459..3797148 1 NC_011353.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3797148 mutH 6972015 mutH Escherichia coli O157:H7 str. EC4115 DNA mismatch repair protein YP_002272295.1 3796459 D 444450 CDS YP_002272296.1 209399872 6971840 3797217..3797930 1 NC_011353.1 identified by match to protein family HMM PF03741; TerC family integral membrane protein 3797930 6971840 ECH74115_4099 Escherichia coli O157:H7 str. EC4115 TerC family integral membrane protein YP_002272296.1 3797217 D 444450 CDS YP_002272297.1 209396434 6971031 3798068..3798286 1 NC_011353.1 identified by match to protein family HMM PF06004; lipoprotein 3798286 6971031 ECH74115_4100 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002272297.1 3798068 D 444450 CDS YP_002272298.1 209397783 6967342 3798394..3799434 1 NC_011353.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3799434 tas 6967342 tas Escherichia coli O157:H7 str. EC4115 aldo-keto reductase YP_002272298.1 3798394 D 444450 CDS YP_002272299.1 209396999 6968771 complement(3799466..3800659) 1 NC_011353.1 identified by match to protein family HMM PF07690; lysophospholipid transporter LplT 3800659 lplT 6968771 lplT Escherichia coli O157:H7 str. EC4115 lysophospholipid transporter LplT YP_002272299.1 3799466 R 444450 CDS YP_002272300.1 209399601 6967941 complement(3800652..3802811) 1 NC_011353.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3802811 aas 6967941 aas Escherichia coli O157:H7 str. EC4115 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_002272300.1 3800652 R 444450 CDS YP_002272301.1 209398804 6972310 3803397..3804428 1 NC_011353.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3804428 galR 6972310 galR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator GalR YP_002272301.1 3803397 D 444450 CDS YP_002272302.1 209399305 6969884 complement(3804435..3805697) 1 NC_011353.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3805697 lysA 6969884 lysA Escherichia coli O157:H7 str. EC4115 diaminopimelate decarboxylase YP_002272302.1 3804435 R 444450 CDS YP_002272303.1 209399771 6970422 3805819..3806754 1 NC_011353.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 3806754 lysR 6970422 lysR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator LysR YP_002272303.1 3805819 D 444450 CDS YP_002272304.1 209397579 6970927 complement(3806741..3807433) 1 NC_011353.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035; racemase 3807433 6970927 ECH74115_4108 Escherichia coli O157:H7 str. EC4115 racemase YP_002272304.1 3806741 R 444450 CDS YP_002272305.1 209400341 6968556 complement(3807562..3808980) 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; arabinose-proton symporter 3808980 araE 6968556 araE Escherichia coli O157:H7 str. EC4115 arabinose-proton symporter YP_002272305.1 3807562 R 444450 CDS YP_002272306.1 209400700 6971538 complement(3809295..3810056) 1 NC_011353.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3810056 kduD 6971538 kduD Escherichia coli O157:H7 str. EC4115 2-deoxy-D-gluconate 3-dehydrogenase YP_002272306.1 3809295 R 444450 CDS YP_002272307.1 209399330 6971923 complement(3810086..3810922) 1 NC_011353.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3810922 kduI 6971923 kduI Escherichia coli O157:H7 str. EC4115 5-keto-4-deoxyuronate isomerase YP_002272307.1 3810086 R 444450 CDS YP_002272308.1 209397550 6970450 complement(3811209..3812390) 1 NC_011353.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3812390 6970450 ECH74115_4113 Escherichia coli O157:H7 str. EC4115 acetyl-CoA acetyltransferase YP_002272308.1 3811209 R 444450 CDS YP_002272309.1 209398062 6968524 3812645..3813874 1 NC_011353.1 identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814; serine transporter family protein 3813874 6968524 ECH74115_4114 Escherichia coli O157:H7 str. EC4115 serine transporter family protein YP_002272309.1 3812645 D 444450 CDS YP_002272310.1 209395725 6969077 3814397..3814966 1 NC_011353.1 hypothetical protein 3814966 6969077 ECH74115_4115 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272310.1 3814397 D 444450 CDS YP_002272311.1 209396874 6966580 3815300..3816109 1 NC_011353.1 identified by match to protein family HMM PF00486; transcriptional regulator 3816109 6966580 ECH74115_4116 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002272311.1 3815300 D 444450 CDS YP_002272312.1 209396618 6967810 3816271..3816585 1 NC_011353.1 hypothetical protein 3816585 6967810 ECH74115_4117 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272312.1 3816271 D 444450 CDS YP_002272313.1 209399481 6967537 complement(3816618..3816743) 1 NC_011353.1 identified by glimmer; hypothetical protein 3816743 6967537 ECH74115_4118 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272313.1 3816618 R 444450 CDS YP_002272314.1 209398139 6970615 complement(3817299..3817535) 1 NC_011353.1 identified by glimmer; hypothetical protein 3817535 6970615 ECH74115_4119 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272314.1 3817299 R 444450 CDS YP_002272315.1 209396603 6967205 complement(3818212..3818334) 1 NC_011353.1 identified by glimmer; hypothetical protein 3818334 6967205 ECH74115_4121 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272315.1 3818212 R 444450 CDS YP_002272316.1 209400096 6967520 3818306..3818797 1 NC_011353.1 identified by match to protein family HMM PF07720; hypothetical protein 3818797 6967520 ECH74115_4122 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272316.1 3818306 D 444450 CDS YP_002272317.1 209400373 6971278 3819131..3820507 1 NC_011353.1 identified by match to protein family HMM PF00486; match to protein family HMM PF07719; transcriptional regulator 3820507 6971278 ECH74115_4123 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002272317.1 3819131 D 444450 CDS YP_002272318.1 209398670 6971573 3820674..3820892 1 NC_011353.1 hypothetical protein 3820892 6971573 ECH74115_4124 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272318.1 3820674 D 444450 CDS YP_002272319.1 209397630 6969740 3820977..3821480 1 NC_011353.1 identified by match to protein family HMM PF01464; lytic transglycosylase PilT 3821480 6969740 ECH74115_4125 Escherichia coli O157:H7 str. EC4115 lytic transglycosylase PilT YP_002272319.1 3820977 D 444450 CDS YP_002272320.1 209398226 6968612 complement(3821499..3822131) 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 3822131 6968612 ECH74115_4126 Escherichia coli O157:H7 str. EC4115 LuxR family transcriptional regulator YP_002272320.1 3821499 R 444450 CDS YP_002272321.1 209397604 6969257 complement(3822110..3822277) 1 NC_011353.1 identified by glimmer; hypothetical protein 3822277 6969257 ECH74115_4127 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272321.1 3822110 R 444450 CDS YP_002272322.1 209396060 6968584 complement(3822354..3822785) 1 NC_011353.1 hypothetical protein 3822785 6968584 ECH74115_4128 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272322.1 3822354 R 444450 CDS YP_002272323.1 209397562 6970577 complement(3823004..3823159) 1 NC_011353.1 hypothetical protein 3823159 6970577 ECH74115_4130 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272323.1 3823004 R 444450 CDS YP_002272324.1 209398387 6968538 complement(3823601..3824335) 1 NC_011353.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544; type III secretion apparatus lipoprotein EprK 3824335 6968538 ECH74115_4131 Escherichia coli O157:H7 str. EC4115 type III secretion apparatus lipoprotein EprK YP_002272324.1 3823601 R 444450 CDS YP_002272325.1 209399138 6969431 complement(3824332..3824664) 1 NC_011353.1 type III secretion apparatus protein EprJ 3824664 eprJ 6969431 eprJ Escherichia coli O157:H7 str. EC4115 type III secretion apparatus protein EprJ YP_002272325.1 3824332 R 444450 CDS YP_002272326.1 209399756 6970244 complement(3824684..3824923) 1 NC_011353.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105; type III secretion apparatus needle protein 3824923 eprI 6970244 eprI Escherichia coli O157:H7 str. EC4115 type III secretion apparatus needle protein YP_002272326.1 3824684 R 444450 CDS YP_002272327.1 209396063 6971863 complement(3825680..3825817) 1 NC_011353.1 identified by glimmer; hypothetical protein 3825817 6971863 ECH74115_4135 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272327.1 3825680 R 444450 CDS YP_002272328.1 209396812 6966940 3826375..3826875 1 NC_011353.1 identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 3826875 6966940 ECH74115_4136 Escherichia coli O157:H7 str. EC4115 LuxR family transcriptional regulator YP_002272328.1 3826375 D 444450 CDS YP_002272329.1 209399671 6967744 complement(3827232..3828353) 1 NC_011353.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; surface presentation of antigens protein SpaS 3828353 6967744 ECH74115_4137 Escherichia coli O157:H7 str. EC4115 surface presentation of antigens protein SpaS YP_002272329.1 3827232 R 444450 CDS YP_002272330.1 209399840 6971290 complement(3829131..3829391) 1 NC_011353.1 identified by match to protein family HMM PF01313; match to protein family HMM TIGR01403; type III secretion apparatus protein EpaQ 3829391 epaQ 6971290 epaQ Escherichia coli O157:H7 str. EC4115 type III secretion apparatus protein EpaQ YP_002272330.1 3829131 R 444450 CDS YP_002272331.1 209399259 6970997 complement(3829402..3830067) 1 NC_011353.1 part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP 3830067 spaP 6970997 spaP Escherichia coli O157:H7 str. EC4115 surface presentation of antigens protein SpaP YP_002272331.1 3829402 R 444450 CDS YP_002272332.1 209397825 6969457 complement(3831003..3831572) 1 NC_011353.1 type III secretion apparatus protein 3831572 6969457 ECH74115_4143 Escherichia coli O157:H7 str. EC4115 type III secretion apparatus protein YP_002272332.1 3831003 R 444450 CDS YP_002272333.1 209396721 6968604 complement(3831856..3832323) 1 NC_011353.1 protein EivI 3832323 6968604 ECH74115_4145 Escherichia coli O157:H7 str. EC4115 protein EivI YP_002272333.1 3831856 R 444450 CDS YP_002272334.1 209396176 6967647 complement(3832304..3833596) 1 NC_011353.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase; ATP synthase SpaL 3833596 6967647 ECH74115_4146 Escherichia coli O157:H7 str. EC4115 ATP synthase SpaL YP_002272334.1 3832304 R 444450 CDS YP_002272335.1 209398095 6967062 complement(3833628..3835688) 1 NC_011353.1 identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399; type III secretion protein, HrcV family 3835688 6967062 ECH74115_4147 Escherichia coli O157:H7 str. EC4115 type III secretion protein, HrcV family YP_002272335.1 3833628 R 444450 CDS YP_002272336.1 209400791 6969113 complement(3835681..3836826) 1 NC_011353.1 identified by match to protein family HMM PF02523; match to protein family HMM TIGR02568; protein EivE 3836826 6969113 ECH74115_4148 Escherichia coli O157:H7 str. EC4115 protein EivE YP_002272336.1 3835681 R 444450 CDS YP_002272337.1 209395847 6972017 complement(3836831..3838534) 1 NC_011353.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516; type III secretion outer membrane pore, YscC/HrcC family 3838534 6972017 ECH74115_4149 Escherichia coli O157:H7 str. EC4115 type III secretion outer membrane pore, YscC/HrcC family YP_002272337.1 3836831 R 444450 CDS YP_002272338.1 209396397 6966705 complement(3838531..3839280) 1 NC_011353.1 identified by match to protein family HMM PF00165; protein EivF 3839280 6966705 ECH74115_4150 Escherichia coli O157:H7 str. EC4115 protein EivF YP_002272338.1 3838531 R 444450 CDS YP_002272339.1 209399941 6967304 complement(3839626..3839805) 1 NC_011353.1 hypothetical protein 3839805 6967304 ECH74115_4151 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272339.1 3839626 R 444450 CDS YP_002272340.1 209398939 6972382 complement(3841863..3842618) 1 NC_011353.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; peptidase, M23B family 3842618 6972382 ECH74115_4155 Escherichia coli O157:H7 str. EC4115 peptidase, M23B family YP_002272340.1 3841863 R 444450 CDS YP_002272341.1 209396943 6970033 3843034..3845331 1 NC_011353.1 molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3845331 xdhA 6970033 xdhA Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase subunit XdhA YP_002272341.1 3843034 D 444450 CDS YP_002272342.1 209397706 6967881 3845342..3846220 1 NC_011353.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3846220 xdhB 6967881 xdhB Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase subunit XdhB YP_002272342.1 3845342 D 444450 CDS YP_002272343.1 209400478 6968690 3846217..3846696 1 NC_011353.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3846696 xdhC 6968690 xdhC Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase subunit XdhC YP_002272343.1 3846217 D 444450 CDS YP_002272344.1 209400999 6971683 complement(3846736..3848514) 1 NC_011353.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; Fis family sigma-54 dependent transcriptional regulator 3848514 6971683 ECH74115_4159 Escherichia coli O157:H7 str. EC4115 Fis family sigma-54 dependent transcriptional regulator YP_002272344.1 3846736 R 444450 CDS YP_002272345.1 209398899 6972241 3848990..3850180 1 NC_011353.1 identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316; aspartate/ornithine carbamoyltransferase family protein 3850180 6972241 ECH74115_4160 Escherichia coli O157:H7 str. EC4115 aspartate/ornithine carbamoyltransferase family protein YP_002272345.1 3848990 D 444450 CDS YP_002272346.1 209398501 6969989 3850238..3851434 1 NC_011353.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3851434 6969989 ECH74115_4161 Escherichia coli O157:H7 str. EC4115 diaminopropionate ammonia-lyase YP_002272346.1 3850238 D 444450 CDS YP_002272347.1 209396009 6969559 3851492..3852703 1 NC_011353.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3852703 6969559 ECH74115_4162 Escherichia coli O157:H7 str. EC4115 peptidase YP_002272347.1 3851492 D 444450 CDS YP_002272348.1 209396584 6966881 3852744..3854141 1 NC_011353.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3854141 hyuA 6966881 hyuA Escherichia coli O157:H7 str. EC4115 phenylhydantoinase YP_002272348.1 3852744 D 444450 CDS YP_002272349.1 209400118 6967499 3854189..3855121 1 NC_011353.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3855121 6967499 ECH74115_4164 Escherichia coli O157:H7 str. EC4115 carbamate kinase YP_002272349.1 3854189 D 444450 CDS YP_002272350.1 209400720 6971302 complement(3855162..3856787) 1 NC_011353.1 identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309; xanthine dehydrogenase accessory factor 3856787 6971302 ECH74115_4165 Escherichia coli O157:H7 str. EC4115 xanthine dehydrogenase accessory factor YP_002272350.1 3855162 R 444450 CDS YP_002272351.1 209399415 6971944 complement(3856835..3857605) 1 NC_011353.1 identified by match to protein family HMM TIGR03172; hypothetical protein 3857605 6971944 ECH74115_4166 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272351.1 3856835 R 444450 CDS YP_002272352.1 209400270 6970541 3857708..3858286 1 NC_011353.1 identified by match to protein family HMM TIGR03310; hypothetical protein 3858286 6970541 ECH74115_4167 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272352.1 3857708 D 444450 CDS YP_002272353.1 209398177 6971463 3858608..3861706 1 NC_011353.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3861706 6971463 ECH74115_4168 Escherichia coli O157:H7 str. EC4115 selenate reductase subunit YgfK YP_002272353.1 3858608 D 444450 CDS YP_002272354.1 209398297 6969203 3861709..3863037 1 NC_011353.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3863037 ssnA 6969203 ssnA Escherichia coli O157:H7 str. EC4115 chlorohydrolase/aminohydrolase YP_002272354.1 3861709 D 444450 CDS YP_002272355.1 209397235 6969333 3863087..3863866 1 NC_011353.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3863866 6969333 ECH74115_4170 Escherichia coli O157:H7 str. EC4115 selenate reductase subunit YgfM YP_002272355.1 3863087 D 444450 CDS YP_002272356.1 209399134 6968193 3863863..3866733 1 NC_011353.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3866733 6968193 ECH74115_4171 Escherichia coli O157:H7 str. EC4115 selenate reductase subunit YgfN YP_002272356.1 3863863 D 444450 CDS YP_002272357.1 209400599 6970237 3866898..3868298 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine/uracil permease family protein 3868298 6970237 ECH74115_4172 Escherichia coli O157:H7 str. EC4115 xanthine/uracil permease family protein YP_002272357.1 3866898 D 444450 CDS YP_002272358.1 209398700 6971810 3868316..3869632 1 NC_011353.1 Catalyzes the deamination of guanine; guanine deaminase 3869632 guaD 6971810 guaD Escherichia coli O157:H7 str. EC4115 guanine deaminase YP_002272358.1 3868316 D 444450 CDS YP_002272359.1 209396772 6969772 3869668..3871035 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inorganic anion transporter sulfate permease (SulP) family 3871035 6969772 ECH74115_4174 Escherichia coli O157:H7 str. EC4115 inorganic anion transporter sulfate permease (SulP) family YP_002272359.1 3869668 D 444450 CDS YP_002272360.1 209398308 6966902 complement(3871559..3873484) 1 NC_011353.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3873484 6966902 ECH74115_4176 Escherichia coli O157:H7 str. EC4115 oxidoreductase Fe-S binding subunit YP_002272360.1 3871559 R 444450 CDS YP_002272361.1 209397544 6969345 3873785..3875362 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 3875362 6969345 ECH74115_4177 Escherichia coli O157:H7 str. EC4115 xanthine permease YP_002272361.1 3873785 D 444450 CDS YP_002272362.1 209397252 6968518 3875364..3875489 1 NC_011353.1 identified by glimmer; hypothetical protein 3875489 6968518 ECH74115_4178 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272362.1 3875364 D 444450 CDS YP_002272363.1 209397125 6968210 3875612..3876160 1 NC_011353.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3876160 idi 6968210 idi Escherichia coli O157:H7 str. EC4115 isopentenyl-diphosphate delta-isomerase YP_002272363.1 3875612 D 444450 CDS YP_002272364.1 209398148 6968074 complement(3876203..3877720) 1 NC_011353.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3877720 lysS 6968074 lysS Escherichia coli O157:H7 str. EC4115 lysyl-tRNA synthetase YP_002272364.1 3876203 R 444450 CDS YP_002272365.1 209396942 6966777 3878612..3878767 1 NC_011353.1 hypothetical protein 3878767 6966777 ECH74115_4182 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272365.1 3878612 D 444450 CDS YP_002272366.1 209400065 6967880 complement(3878919..3880652) 1 NC_011353.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3880652 recJ 6967880 recJ Escherichia coli O157:H7 str. EC4115 ssDNA exonuclease RecJ YP_002272366.1 3878919 R 444450 CDS YP_002272367.1 209399808 6971244 complement(3880658..3881368) 1 NC_011353.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3881368 dsbC 6971244 dsbC Escherichia coli O157:H7 str. EC4115 thiol:disulfide interchange protein DsbC YP_002272367.1 3880658 R 444450 CDS YP_002272368.1 209398903 6970965 complement(3881393..3882289) 1 NC_011353.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3882289 xerD 6970965 xerD Escherichia coli O157:H7 str. EC4115 site-specific tyrosine recombinase XerD YP_002272368.1 3881393 R 444450 CDS YP_002272369.1 209398603 6969993 3882401..3882922 1 NC_011353.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3882922 fldB 6969993 fldB Escherichia coli O157:H7 str. EC4115 flavodoxin FldB YP_002272369.1 3882401 D 444450 CDS YP_002272370.1 209399319 6969666 complement(3882962..3883348) 1 NC_011353.1 identified by match to protein family HMM PF07254; hypothetical protein 3883348 6969666 ECH74115_4187 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272370.1 3882962 R 444450 CDS YP_002272371.1 209397339 6970438 complement(3883350..3883616) 1 NC_011353.1 identified by match to protein family HMM PF03937; hypothetical protein 3883616 6970438 ECH74115_4188 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272371.1 3883350 R 444450 CDS YP_002272372.1 209399860 6968306 3883609..3883782 1 NC_011353.1 identified by glimmer; hypothetical protein 3883782 6968306 ECH74115_4189 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272372.1 3883609 D 444450 CDS YP_002272373.1 209400648 6971019 3883859..3884839 1 NC_011353.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3884839 6971019 ECH74115_4190 Escherichia coli O157:H7 str. EC4115 global regulator YP_002272373.1 3883859 D 444450 CDS YP_002272374.1 209400695 6971864 complement(3884916..3885575) 1 NC_011353.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin III family channel protein 3885575 6971864 ECH74115_4191 Escherichia coli O157:H7 str. EC4115 hemolysin III family channel protein YP_002272374.1 3884916 R 444450 CDS YP_002272375.1 209398823 6971917 complement(3885739..3886050) 1 NC_011353.1 identified by match to protein family HMM PF04266; hypothetical protein 3886050 6971917 ECH74115_4192 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272375.1 3885739 R 444450 CDS YP_002272376.1 209399585 6969906 3886089..3887528 1 NC_011353.1 identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase 3887528 bglA 6969906 bglA Escherichia coli O157:H7 str. EC4115 6-phospho-beta-glucosidase YP_002272376.1 3886089 D 444450 CDS YP_002272377.1 209397624 6970726 complement(3887694..3890567) 1 NC_011353.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3890567 gcvP 6970726 gcvP Escherichia coli O157:H7 str. EC4115 glycine dehydrogenase YP_002272377.1 3887694 R 444450 CDS YP_002272378.1 209397690 6968606 complement(3890685..3891074) 1 NC_011353.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3891074 gcvH 6968606 gcvH Escherichia coli O157:H7 str. EC4115 glycine cleavage system protein H YP_002272378.1 3890685 R 444450 CDS YP_002272379.1 209395867 6968673 complement(3891098..3892192) 1 NC_011353.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3892192 gcvT 6968673 gcvT Escherichia coli O157:H7 str. EC4115 glycine cleavage system aminomethyltransferase T YP_002272379.1 3891098 R 444450 CDS YP_002272380.1 209396637 6966729 complement(3892368..3892496) 1 NC_011353.1 hypothetical protein 3892496 6966729 ECH74115_4197 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272380.1 3892368 R 444450 CDS YP_002272381.1 209397002 6967557 3892453..3892566 1 NC_011353.1 identified by glimmer; hypothetical protein 3892566 6967557 ECH74115_4198 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272381.1 3892453 D 444450 CDS YP_002272382.1 209397458 6967944 complement(3892640..3893842) 1 NC_011353.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988; hypothetical protein 3893842 6967944 ECH74115_4199 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272382.1 3892640 R 444450 CDS YP_002272383.1 209399230 6968429 complement(3893866..3895044) 1 NC_011353.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3895044 ubiH 6968429 ubiH Escherichia coli O157:H7 str. EC4115 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002272383.1 3893866 R 444450 CDS YP_002272384.1 209398591 6970341 complement(3895041..3896366) 1 NC_011353.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3896366 pepP 6970341 pepP Escherichia coli O157:H7 str. EC4115 proline aminopeptidase P II YP_002272384.1 3895041 R 444450 CDS YP_002272385.1 209398130 6969652 complement(3896392..3896970) 1 NC_011353.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3896970 6969652 ECH74115_4202 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272385.1 3896392 R 444450 CDS YP_002272386.1 209397387 6969152 3897138..3897467 1 NC_011353.1 identified by match to protein family HMM PF05164; Z-ring-associated protein 3897467 6969152 ECH74115_4203 Escherichia coli O157:H7 str. EC4115 Z-ring-associated protein YP_002272386.1 3897138 D 444450 CDS YP_002272387.1 209399336 6972261 3897713..3898315 1 NC_011353.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3898315 6972261 ECH74115_4205 Escherichia coli O157:H7 str. EC4115 ligase YP_002272387.1 3897713 D 444450 CDS YP_002272388.1 209398529 6972309 complement(3899097..3900329) 1 NC_011353.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3900329 serA 6972309 serA Escherichia coli O157:H7 str. EC4115 D-3-phosphoglycerate dehydrogenase YP_002272388.1 3899097 R 444450 CDS YP_002272389.1 209400353 6969588 3900358..3900480 1 NC_011353.1 identified by glimmer; hypothetical protein 3900480 6969588 ECH74115_4209 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272389.1 3900358 D 444450 CDS YP_002272390.1 209399759 6971551 complement(3900584..3901243) 1 NC_011353.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3901243 rpiA 6971551 rpiA Escherichia coli O157:H7 str. EC4115 ribose-5-phosphate isomerase A YP_002272390.1 3900584 R 444450 CDS YP_002272391.1 209399383 6967243 3901626..3902519 1 NC_011353.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3902519 argP 6967243 argP Escherichia coli O157:H7 str. EC4115 chromosome replication initiation inhibitor protein YP_002272391.1 3901626 D 444450 CDS YP_002272392.1 209400202 6970508 3902723..3904867 1 NC_011353.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3904867 scpA 6970508 scpA Escherichia coli O157:H7 str. EC4115 methylmalonyl-CoA mutase YP_002272392.1 3902723 D 444450 CDS YP_002272393.1 209396779 6971390 3904860..3905855 1 NC_011353.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3905855 6971390 ECH74115_4214 Escherichia coli O157:H7 str. EC4115 arginine/ornithine transport system ATPase YP_002272393.1 3904860 D 444450 CDS YP_002272394.1 209400369 6967709 3905866..3906651 1 NC_011353.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3906651 6967709 ECH74115_4215 Escherichia coli O157:H7 str. EC4115 methylmalonyl-CoA decarboxylase YP_002272394.1 3905866 D 444450 CDS YP_002272395.1 209399176 6971568 3906675..3908153 1 NC_011353.1 identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458; acetyl-CoA hydrolase/transferase 3908153 6971568 ECH74115_4217 Escherichia coli O157:H7 str. EC4115 acetyl-CoA hydrolase/transferase YP_002272395.1 3906675 D 444450 CDS YP_002272396.1 209398049 6969481 complement(3909213..3909953) 1 NC_011353.1 identified by match to protein family HMM PF04402; hypothetical protein 3909953 6969481 ECH74115_4219 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272396.1 3909213 R 444450 CDS YP_002272397.1 209397283 6969064 complement(3910046..3910681) 1 NC_011353.1 Involved in the export of arginine; arginine exporter protein 3910681 argO 6969064 argO Escherichia coli O157:H7 str. EC4115 arginine exporter protein YP_002272397.1 3910046 R 444450 CDS YP_002272398.1 209400812 6968244 complement(3910820..3911680) 1 NC_011353.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3911680 mscS 6968244 mscS Escherichia coli O157:H7 str. EC4115 mechanosensitive channel MscS YP_002272398.1 3910820 R 444450 CDS YP_002272399.1 209397768 6972040 complement(3912038..3913117) 1 NC_011353.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3913117 fbaA 6972040 fbaA Escherichia coli O157:H7 str. EC4115 fructose-bisphosphate aldolase YP_002272399.1 3912038 R 444450 CDS YP_002272400.1 209396737 6968756 complement(3913332..3914495) 1 NC_011353.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3914495 pgk 6968756 pgk Escherichia coli O157:H7 str. EC4115 phosphoglycerate kinase YP_002272400.1 3913332 R 444450 CDS YP_002272401.1 209396324 6967663 complement(3914545..3915564) 1 NC_011353.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3915564 epd 6967663 epd Escherichia coli O157:H7 str. EC4115 erythrose 4-phosphate dehydrogenase YP_002272401.1 3914545 R 444450 CDS YP_002272402.1 209400091 6967221 3915936..3916367 1 NC_011353.1 identified by match to protein family HMM PF03479; hypothetical protein 3916367 6967221 ECH74115_4225 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272402.1 3915936 D 444450 CDS YP_002272403.1 209400861 6971272 3916390..3916968 1 NC_011353.1 hypothetical protein 3916968 6971272 ECH74115_4226 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272403.1 3916390 D 444450 CDS YP_002272404.1 209397965 6972092 3916969..3917676 1 NC_011353.1 hypothetical protein 3917676 6972092 ECH74115_4227 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272404.1 3916969 D 444450 CDS YP_002272405.1 209399401 6968970 3917664..3918341 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3918341 6968970 ECH74115_4228 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272405.1 3917664 D 444450 CDS YP_002272406.1 209398012 6970527 3918335..3919012 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3919012 6970527 ECH74115_4230 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272406.1 3918335 D 444450 CDS YP_002272407.1 209397256 6969024 complement(3918984..3919697) 1 NC_011353.1 fructose transport system kinase 3919697 frcK 6969024 frcK Escherichia coli O157:H7 str. EC4115 fructose transport system kinase YP_002272407.1 3918984 R 444450 CDS YP_002272408.1 209396295 6968214 complement(3919694..3920203) 1 NC_011353.1 identified by match to protein family HMM PF05068; DNA-binding transcriptional regulator 3920203 6968214 ECH74115_4231 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002272408.1 3919694 R 444450 CDS YP_002272409.1 209396507 6967190 complement(3920225..3921190) 1 NC_011353.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330; fructose-1,6-bisphosphatase II-like protein 3921190 glpX2 6967190 glpX2 Escherichia coli O157:H7 str. EC4115 fructose-1,6-bisphosphatase II-like protein YP_002272409.1 3920225 R 444450 CDS YP_002272410.1 209397984 6967419 complement(3921187..3922464) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-sorbose 1-phosphate reductase 3922464 sorE 6967419 sorE Escherichia coli O157:H7 str. EC4115 L-sorbose 1-phosphate reductase YP_002272410.1 3921187 R 444450 CDS YP_002272411.1 209398789 6968995 complement(3922479..3923867) 1 NC_011353.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit cryptic EIICB 3923867 6968995 ECH74115_4234 Escherichia coli O157:H7 str. EC4115 PTS system mannitol-specific transporter subunit cryptic EIICB YP_002272411.1 3922479 R 444450 CDS YP_002272412.1 209399343 6969867 complement(3923895..3924338) 1 NC_011353.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3924338 cmtB 6969867 cmtB Escherichia coli O157:H7 str. EC4115 mannitol phosphotransferase subunit EIIA YP_002272412.1 3923895 R 444450 CDS YP_002272413.1 209400255 6970463 complement(3924348..3924470) 1 NC_011353.1 identified by glimmer; hypothetical protein 3924470 6970463 ECH74115_4236 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272413.1 3924348 R 444450 CDS YP_002272414.1 209400304 6971447 complement(3924652..3926643) 1 NC_011353.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3926643 tktA 6971447 tktA Escherichia coli O157:H7 str. EC4115 transketolase YP_002272414.1 3924652 R 444450 CDS YP_002272415.1 209400876 6971499 3926921..3927679 1 NC_011353.1 identified by match to protein family HMM PF01435; peptidase, M48B family 3927679 6971499 ECH74115_4238 Escherichia coli O157:H7 str. EC4115 peptidase, M48B family YP_002272415.1 3926921 D 444450 CDS YP_002272416.1 209396386 6972108 complement(3927885..3928805) 1 NC_011353.1 catalyzes the formation of putrescine from agmatine; agmatinase 3928805 speB 6972108 speB Escherichia coli O157:H7 str. EC4115 agmatinase YP_002272416.1 3927885 R 444450 CDS YP_002272417.1 209397312 6967291 complement(3928941..3929672) 1 NC_011353.1 lipoprotein 3929672 6967291 ECH74115_4240 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002272417.1 3928941 R 444450 CDS YP_002272418.1 209398776 6968274 complement(3929818..3931716) 1 NC_011353.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3931716 speA 6968274 speA Escherichia coli O157:H7 str. EC4115 arginine decarboxylase YP_002272418.1 3929818 R 444450 CDS YP_002272419.1 209397594 6969854 complement(3931803..3931934) 1 NC_011353.1 hypothetical protein 3931934 6969854 ECH74115_4242 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272419.1 3931803 R 444450 CDS YP_002272420.1 209398337 6968573 3932269..3932394 1 NC_011353.1 identified by glimmer; hypothetical protein 3932394 6968573 ECH74115_4243 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272420.1 3932269 D 444450 CDS YP_002272421.1 209398749 6969377 3932589..3933743 1 NC_011353.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3933743 metK 6969377 metK Escherichia coli O157:H7 str. EC4115 S-adenosylmethionine synthetase YP_002272421.1 3932589 D 444450 CDS YP_002272422.1 209400077 6969825 3933806..3934021 1 NC_011353.1 identified by glimmer; hypothetical protein 3934021 6969825 ECH74115_4245 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272422.1 3933806 D 444450 CDS YP_002272423.1 209400814 6971256 3934180..3935574 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; galactose-proton symporter 3935574 galP 6971256 galP Escherichia coli O157:H7 str. EC4115 galactose-proton symporter YP_002272423.1 3934180 D 444450 CDS YP_002272424.1 209400553 6972042 3935597..3936148 1 NC_011353.1 identified by match to protein family HMM PF03926; hypothetical protein 3936148 sprT 6972042 sprT Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272424.1 3935597 D 444450 CDS YP_002272425.1 209396449 6971762 3936243..3936950 1 NC_011353.1 identified by match to protein family HMM PF04231; endonuclease I 3936950 endA 6971762 endA Escherichia coli O157:H7 str. EC4115 endonuclease I YP_002272425.1 3936243 D 444450 CDS YP_002272426.1 209396394 6967359 3937030..3937761 1 NC_011353.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3937761 rsmE 6967359 rsmE Escherichia coli O157:H7 str. EC4115 16S ribosomal RNA methyltransferase RsmE YP_002272426.1 3937030 D 444450 CDS YP_002272427.1 209397305 6967300 3937774..3938721 1 NC_011353.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3938721 gshB 6967300 gshB Escherichia coli O157:H7 str. EC4115 glutathione synthetase YP_002272427.1 3937774 D 444450 CDS YP_002272428.1 209397908 6968267 3938833..3939396 1 NC_011353.1 identified by match to protein family HMM PF02622; hypothetical protein 3939396 6968267 ECH74115_4251 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272428.1 3938833 D 444450 CDS YP_002272429.1 209396593 6968906 3939396..3939812 1 NC_011353.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3939812 6968906 ECH74115_4252 Escherichia coli O157:H7 str. EC4115 Holliday junction resolvase-like protein YP_002272429.1 3939396 D 444450 CDS YP_002272430.1 209396613 6967508 complement(3940003..3941028) 1 NC_011353.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility family protein 3941028 6967508 ECH74115_4253 Escherichia coli O157:H7 str. EC4115 twitching motility family protein YP_002272430.1 3940003 R 444450 CDS YP_002272431.1 209395868 6967532 3941001..3941705 1 NC_011353.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044; pyridoxal phosphate enzyme, YggS family 3941705 6967532 ECH74115_4254 Escherichia coli O157:H7 str. EC4115 pyridoxal phosphate enzyme, YggS family YP_002272431.1 3941001 D 444450 CDS YP_002272432.1 209400119 6966732 3941723..3942289 1 NC_011353.1 identified by match to protein family HMM PF02325; hypothetical protein 3942289 6966732 ECH74115_4255 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272432.1 3941723 D 444450 CDS YP_002272433.1 209399373 6971303 3942286..3942576 1 NC_011353.1 identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; hypothetical protein 3942576 6971303 ECH74115_4256 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272433.1 3942286 D 444450 CDS YP_002272434.1 209399636 6970498 3942584..3943177 1 NC_011353.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3943177 rdgB 6970498 rdgB Escherichia coli O157:H7 str. EC4115 deoxyribonucleotide triphosphate pyrophosphatase YP_002272434.1 3942584 D 444450 CDS YP_002272435.1 209398861 6970781 3943170..3944306 1 NC_011353.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3944306 6970781 ECH74115_4258 Escherichia coli O157:H7 str. EC4115 coproporphyrinogen III oxidase YP_002272435.1 3943170 D 444450 CDS YP_002272436.1 209397826 6969947 complement(3944549..3945556) 1 NC_011353.1 identified by match to protein family HMM PF06717; hypothetical protein 3945556 6969947 ECH74115_4259 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272436.1 3944549 R 444450 CDS YP_002272437.1 209397059 6968817 complement(3945673..3946719) 1 NC_011353.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3946719 ansB 6968817 ansB Escherichia coli O157:H7 str. EC4115 L-asparaginase II YP_002272437.1 3945673 R 444450 CDS YP_002272438.1 209397261 6968005 complement(3946895..3947614) 1 NC_011353.1 hypothetical protein 3947614 6968005 ECH74115_4261 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272438.1 3946895 R 444450 CDS YP_002272439.1 209399019 6968219 complement(3947635..3947775) 1 NC_011353.1 hypothetical protein 3947775 6968219 ECH74115_4262 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272439.1 3947635 R 444450 CDS YP_002272440.1 209397680 6970119 complement(3947798..3948124) 1 NC_011353.1 identified by match to protein family HMM PF04320; hypothetical protein 3948124 6970119 ECH74115_4263 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272440.1 3947798 R 444450 CDS YP_002272441.1 209398228 6968663 complement(3948124..3948843) 1 NC_011353.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3948843 trmB 6968663 trmB Escherichia coli O157:H7 str. EC4115 tRNA (guanine-N(7)-)-methyltransferase YP_002272441.1 3948124 R 444450 CDS YP_002272442.1 209395967 6969259 3949004..3950056 1 NC_011353.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; adenine DNA glycosylase 3950056 mutY 6969259 mutY Escherichia coli O157:H7 str. EC4115 adenine DNA glycosylase YP_002272442.1 3949004 D 444450 CDS YP_002272443.1 209396699 6966836 3950084..3950359 1 NC_011353.1 identified by match to protein family HMM PF04362; hypothetical protein 3950359 6966836 ECH74115_4266 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272443.1 3950084 D 444450 CDS YP_002272444.1 209400709 6967623 3950424..3951503 1 NC_011353.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3951503 mltC 6967623 mltC Escherichia coli O157:H7 str. EC4115 murein transglycosylase C YP_002272444.1 3950424 D 444450 CDS YP_002272445.1 209400129 6971932 3951705..3952961 1 NC_011353.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside permease NupG 3952961 nupG 6971932 nupG Escherichia coli O157:H7 str. EC4115 nucleoside permease NupG YP_002272445.1 3951705 D 444450 CDS YP_002272446.1 209399569 6971314 complement(3953011..3955146) 1 NC_011353.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase 3955146 speC 6971314 speC Escherichia coli O157:H7 str. EC4115 ornithine decarboxylase YP_002272446.1 3953011 R 444450 CDS YP_002272447.1 209398981 6970707 3955544..3956251 1 NC_011353.1 identified by match to protein family HMM PF04474; hypothetical protein 3956251 6970707 ECH74115_4270 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272447.1 3955544 D 444450 CDS YP_002272448.1 209398968 6972337 3956630..3957895 1 NC_011353.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family protein 3957895 6972337 ECH74115_4272 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family protein YP_002272448.1 3956630 D 444450 CDS YP_002272449.1 209400616 6970064 complement(3958012..3958632) 1 NC_011353.1 ISSfl4 ORF3 3958632 6970064 ECH74115_4273 Escherichia coli O157:H7 str. EC4115 ISSfl4 ORF3 YP_002272449.1 3958012 R 444450 CDS YP_002272450.1 209399039 6971828 3958886..3959560 1 NC_011353.1 identified by match to protein family HMM PF01527; ISSfl4 ORF1 3959560 6971828 ECH74115_4274 Escherichia coli O157:H7 str. EC4115 ISSfl4 ORF1 YP_002272450.1 3958886 D 444450 CDS YP_002272451.1 209397595 6970140 3959557..3959904 1 NC_011353.1 identified by match to protein family HMM PF05717; ISSfl4 ORF2 3959904 6970140 ECH74115_4275 Escherichia coli O157:H7 str. EC4115 ISSfl4 ORF2 YP_002272451.1 3959557 D 444450 CDS YP_002272452.1 209396139 6969371 complement(3961173..3962117) 1 NC_011353.1 DNA helicase II 3962117 6969371 ECH74115_4277 Escherichia coli O157:H7 str. EC4115 DNA helicase II YP_002272452.1 3961173 R 444450 CDS YP_002272453.1 209396143 6967022 complement(3962226..3962759) 1 NC_011353.1 identified by match to protein family HMM PF06316; outer membrane invasion protein 3962759 6967022 ECH74115_4278 Escherichia coli O157:H7 str. EC4115 outer membrane invasion protein YP_002272453.1 3962226 R 444450 CDS YP_002272454.1 209396733 6967026 complement(3963347..3963523) 1 NC_011353.1 hypothetical protein 3963523 6967026 ECH74115_4279 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272454.1 3963347 R 444450 CDS YP_002272455.1 209397628 6969482 complement(3965355..3965474) 1 NC_011353.1 identified by glimmer; hypothetical protein 3965474 6969482 ECH74115_4282 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272455.1 3965355 R 444450 CDS YP_002272456.1 209396573 6966989 3965754..3967403 1 NC_011353.1 identified by match to protein family HMM PF07906; Ent protein 3967403 6966989 ECH74115_4284 Escherichia coli O157:H7 str. EC4115 Ent protein YP_002272456.1 3965754 D 444450 CDS YP_002272457.1 209395991 6967487 complement(3967476..3967622) 1 NC_011353.1 identified by glimmer; hypothetical protein 3967622 6967487 ECH74115_4285 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272457.1 3967476 R 444450 CDS YP_002272458.1 209397731 6966862 3968011..3969000 1 NC_011353.1 NleB 3969000 6966862 ECH74115_4286 Escherichia coli O157:H7 str. EC4115 NleB YP_002272458.1 3968011 D 444450 CDS YP_002272459.1 209397037 6968716 3969049..3969723 1 NC_011353.1 NleE 3969723 6968716 ECH74115_4287 Escherichia coli O157:H7 str. EC4115 NleE YP_002272459.1 3969049 D 444450 CDS YP_002272460.1 209400138 6972123 3973861..3974208 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 3974208 6972123 ECH74115_4291 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002272460.1 3973861 D 444450 CDS YP_002272461.1 209400142 6971324 3974258..3975796 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 3975796 6971324 ECH74115_4292 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002272461.1 3974258 D 444450 CDS YP_002272462.1 209397523 6971328 3975864..3976022 1 NC_011353.1 IS66 family transposase OrfA 3976022 6971328 ECH74115_4293 Escherichia coli O157:H7 str. EC4115 IS66 family transposase OrfA YP_002272462.1 3975864 D 444450 CDS YP_002272463.1 209396819 6968496 3976019..3976369 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 3976369 6968496 ECH74115_4294 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002272463.1 3976019 D 444450 CDS YP_002272464.1 209396815 6969327 3978077..3978247 1 NC_011353.1 transposase InsF for insertion sequence IS3A/B/C/D/E/fA 3978247 6969327 ECH74115_4298 Escherichia coli O157:H7 str. EC4115 transposase InsF for insertion sequence IS3A/B/C/D/E/fA YP_002272464.1 3978077 D 444450 CDS YP_002272465.1 209396093 6967747 complement(3978213..3978332) 1 NC_011353.1 identified by glimmer; hypothetical protein 3978332 6967747 ECH74115_4297 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272465.1 3978213 R 444450 CDS YP_002272466.1 209399859 6966972 complement(3978491..3979807) 1 NC_011353.1 identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 2 3979807 6966972 ECH74115_4299 Escherichia coli O157:H7 str. EC4115 low-affinity inorganic phosphate transporter 2 YP_002272466.1 3978491 R 444450 CDS YP_002272467.1 209400603 6971018 complement(3980099..3981958) 1 NC_011353.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3981958 gsp 6971018 gsp Escherichia coli O157:H7 str. EC4115 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_002272467.1 3980099 R 444450 CDS YP_002272468.1 209398296 6971814 3982163..3983029 1 NC_011353.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 3983029 6971814 ECH74115_4301 Escherichia coli O157:H7 str. EC4115 glutathione S-transferase YP_002272468.1 3982163 D 444450 CDS YP_002272469.1 209399055 6969332 complement(3983152..3983400) 1 NC_011353.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074; hydrogenase 2 accessory protein HypG 3983400 hybG 6969332 hybG Escherichia coli O157:H7 str. EC4115 hydrogenase 2 accessory protein HypG YP_002272469.1 3983152 R 444450 CDS YP_002272470.1 209396775 6970157 complement(3983413..3983754) 1 NC_011353.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3983754 hypA1 6970157 hypA1 Escherichia coli O157:H7 str. EC4115 hydrogenase nickel incorporation protein HybF YP_002272470.1 3983413 R 444450 CDS YP_002272471.1 209396299 6967705 complement(3983747..3984235) 1 NC_011353.1 hydrogenase 2-specific chaperone 3984235 hybE 6967705 hybE Escherichia coli O157:H7 str. EC4115 hydrogenase 2-specific chaperone YP_002272471.1 3983747 R 444450 CDS YP_002272472.1 209397274 6967194 complement(3984228..3984722) 1 NC_011353.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3984722 hybD 6967194 hybD Escherichia coli O157:H7 str. EC4115 hydrogenase 2 maturation endopeptidase YP_002272472.1 3984228 R 444450 CDS YP_002272473.1 209397380 6968235 complement(3984722..3986425) 1 NC_011353.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3986425 hybC 6968235 hybC Escherichia coli O157:H7 str. EC4115 hydrogenase 2 large subunit YP_002272473.1 3984722 R 444450 CDS YP_002272474.1 209399191 6968346 complement(3986422..3987600) 1 NC_011353.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3987600 hybB 6968346 hybB Escherichia coli O157:H7 str. EC4115 hydrogenase 2 b cytochrome subunit YP_002272474.1 3986422 R 444450 CDS YP_002272475.1 209398622 6970299 complement(3987590..3988576) 1 NC_011353.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3988576 hybA 6970299 hybA Escherichia coli O157:H7 str. EC4115 hydrogenase 2 protein HybA YP_002272475.1 3987590 R 444450 CDS YP_002272476.1 209400392 6969685 complement(3988579..3989697) 1 NC_011353.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3989697 hybO 6969685 hybO Escherichia coli O157:H7 str. EC4115 hydrogenase 2 small subunit YP_002272476.1 3988579 R 444450 CDS YP_002272477.1 209399743 6971593 3989681..3989809 1 NC_011353.1 identified by glimmer; hypothetical protein 3989809 6971593 ECH74115_4310 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272477.1 3989681 D 444450 CDS YP_002272478.1 209397647 6970899 complement(3989886..3990173) 1 NC_011353.1 hypothetical protein 3990173 6970899 ECH74115_4311 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272478.1 3989886 R 444450 CDS YP_002272479.1 209396369 6968630 complement(3990292..3991179) 1 NC_011353.1 identified by match to protein family HMM PF01738; dienelactone hydrolase family protein 3991179 6968630 ECH74115_4312 Escherichia coli O157:H7 str. EC4115 dienelactone hydrolase family protein YP_002272479.1 3990292 R 444450 CDS YP_002272480.1 209399849 6967272 3991336..3992376 1 NC_011353.1 identified by match to protein family HMM PF00248; aldo-keto reductase 3992376 6967272 ECH74115_4313 Escherichia coli O157:H7 str. EC4115 aldo-keto reductase YP_002272480.1 3991336 D 444450 CDS YP_002272481.1 209398917 6971006 complement(3992416..3992910) 1 NC_011353.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645; hypothetical protein 3992910 6971006 ECH74115_4314 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272481.1 3992416 R 444450 CDS YP_002272482.1 209399644 6970009 3993101..3993985 1 NC_011353.1 identified by match to protein family HMM PF00106; oxidoreductase 3993985 6970009 ECH74115_4315 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002272482.1 3993101 D 444450 CDS YP_002272483.1 209399062 6970789 complement(3994257..3994682) 1 NC_011353.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3994682 exbD 6970789 exbD Escherichia coli O157:H7 str. EC4115 biopolymer transport protein ExbD YP_002272483.1 3994257 R 444450 CDS YP_002272484.1 209397203 6970164 complement(3994689..3995423) 1 NC_011353.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3995423 exbB 6970164 exbB Escherichia coli O157:H7 str. EC4115 biopolymer transport protein ExbB YP_002272484.1 3994689 R 444450 CDS YP_002272485.1 209397938 6968159 3995540..3996862 1 NC_011353.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3996862 metC 6968159 metC Escherichia coli O157:H7 str. EC4115 cystathionine beta-lyase YP_002272485.1 3995540 D 444450 CDS YP_002272486.1 209396089 6968941 3997002..3997661 1 NC_011353.1 identified by match to protein family HMM PF09335; hypothetical protein 3997661 6968941 ECH74115_4319 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272486.1 3997002 D 444450 CDS YP_002272487.1 209396822 6966968 complement(3997701..3998600) 1 NC_011353.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06719; AraC family transcriptional regulator 3998600 6966968 ECH74115_4320 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002272487.1 3997701 R 444450 CDS YP_002272488.1 209400234 6967754 complement(3998597..3998743) 1 NC_011353.1 identified by glimmer; hypothetical protein 3998743 6967754 ECH74115_4321 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272488.1 3998597 R 444450 CDS YP_002272489.1 209399675 6971424 3998794..3999957 1 NC_011353.1 identified by match to protein family HMM PF00465; alcohol dehydrogenase yqhD 3999957 yqhD 6971424 yqhD Escherichia coli O157:H7 str. EC4115 alcohol dehydrogenase yqhD YP_002272489.1 3998794 D 444450 CDS YP_002272490.1 209397569 6970823 4000062..4000889 1 NC_011353.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 4000889 dkgA 6970823 dkgA Escherichia coli O157:H7 str. EC4115 2,5-diketo-D-gluconate reductase A YP_002272490.1 4000062 D 444450 CDS YP_002272491.1 209396592 6966901 4002060..4002317 1 NC_011353.1 outer membrane lipoprotein 4002317 6966901 ECH74115_4326 Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein YP_002272491.1 4002060 D 444450 CDS YP_002272492.1 209399855 6967507 complement(4002360..4004579) 1 NC_011353.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein 4004579 6967507 ECH74115_4327 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272492.1 4002360 R 444450 CDS YP_002272493.1 209400459 6971013 complement(4004690..4006102) 1 NC_011353.1 identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409; repressor protein for FtsI 4006102 sufI 6971013 sufI Escherichia coli O157:H7 str. EC4115 repressor protein for FtsI YP_002272493.1 4004690 R 444450 CDS YP_002272494.1 209398402 6971664 complement(4006177..4006914) 1 NC_011353.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase 4006914 plsC 6971664 plsC Escherichia coli O157:H7 str. EC4115 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002272494.1 4006177 R 444450 CDS YP_002272495.1 209398989 6969448 complement(4007148..4009406) 1 NC_011353.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 4009406 parC 6969448 parC Escherichia coli O157:H7 str. EC4115 DNA topoisomerase IV subunit A YP_002272495.1 4007148 R 444450 CDS YP_002272496.1 209396769 6970088 complement(4009544..4011151) 1 NC_011353.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein 4011151 6970088 ECH74115_4331 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272496.1 4009544 R 444450 CDS YP_002272497.1 209397524 6967698 complement(4011260..4011742) 1 NC_011353.1 identified by match to protein family HMM PF06445; transcription activator effector binding domain/DNA gyrase inhibitor domain-containing protein 4011742 6967698 ECH74115_4332 Escherichia coli O157:H7 str. EC4115 transcription activator effector binding domain/DNA gyrase inhibitor domain-containing protein YP_002272497.1 4011260 R 444450 CDS YP_002272498.1 209397881 6968497 complement(4011795..4012187) 1 NC_011353.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein 4012187 6968497 ECH74115_4333 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272498.1 4011795 R 444450 CDS YP_002272499.1 209398732 6968878 4012339..4012998 1 NC_011353.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 4012998 qseB 6968878 qseB Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator QseB YP_002272499.1 4012339 D 444450 CDS YP_002272500.1 209398656 6969806 4012995..4014344 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein QseC 4014344 qseC 6969806 qseC Escherichia coli O157:H7 str. EC4115 sensor protein QseC YP_002272500.1 4012995 D 444450 CDS YP_002272501.1 209400260 6969726 4014454..4015035 1 NC_011353.1 identified by match to protein family HMM PF02525; modulator of drug activity B 4015035 mdaB 6969726 mdaB Escherichia coli O157:H7 str. EC4115 modulator of drug activity B YP_002272501.1 4014454 D 444450 CDS YP_002272502.1 209400805 6971453 4015066..4015380 1 NC_011353.1 identified by match to protein family HMM PF03992; quinol monooxygenase YgiN 4015380 ygiN 6971453 ygiN Escherichia coli O157:H7 str. EC4115 quinol monooxygenase YgiN YP_002272502.1 4015066 D 444450 CDS YP_002272503.1 209399432 6972033 complement(4015425..4016312) 1 NC_011353.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; iron transport system regulatory protein FitR 4016312 fitR 6972033 fitR Escherichia coli O157:H7 str. EC4115 iron transport system regulatory protein FitR YP_002272503.1 4015425 R 444450 CDS YP_002272504.1 209397497 6970560 complement(4016309..4017256) 1 NC_011353.1 identified by match to protein family HMM PF01497; iron ABC transporter periplasmic iron-binding protein FitE 4017256 fitE 6970560 fitE Escherichia coli O157:H7 str. EC4115 iron ABC transporter periplasmic iron-binding protein FitE YP_002272504.1 4016309 R 444450 CDS YP_002272505.1 209400446 6968469 complement(4017267..4018304) 1 NC_011353.1 identified by match to protein family HMM PF01032; iron ABC transporter permease FitD 4018304 fitD 6968469 fitD Escherichia coli O157:H7 str. EC4115 iron ABC transporter permease FitD YP_002272505.1 4017267 R 444450 CDS YP_002272506.1 209398999 6971651 complement(4018313..4019296) 1 NC_011353.1 identified by match to protein family HMM PF01032; iron ABC transporter permease FitC 4019296 fitC 6971651 fitC Escherichia coli O157:H7 str. EC4115 iron ABC transporter permease FitC YP_002272506.1 4018313 R 444450 CDS YP_002272507.1 209395843 6970098 complement(4019293..4020102) 1 NC_011353.1 identified by match to protein family HMM PF00005; iron ABC transporter ATP binding protein FitB 4020102 fitB 6970098 fitB Escherichia coli O157:H7 str. EC4115 iron ABC transporter ATP binding protein FitB YP_002272507.1 4019293 R 444450 CDS YP_002272508.1 209399265 6966700 4020476..4022617 1 NC_011353.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; TonB-dependent outer membrane ferric coprogen receptor FitA 4022617 fitA 6966700 fitA Escherichia coli O157:H7 str. EC4115 TonB-dependent outer membrane ferric coprogen receptor FitA YP_002272508.1 4020476 D 444450 CDS YP_002272509.1 209399667 6970381 complement(4022681..4024573) 1 NC_011353.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 4024573 parE 6970381 parE Escherichia coli O157:H7 str. EC4115 DNA topoisomerase IV subunit B YP_002272509.1 4022681 R 444450 CDS YP_002272510.1 209400424 6970814 complement(4024602..4025183) 1 NC_011353.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 4025183 yqiA 6970814 yqiA Escherichia coli O157:H7 str. EC4115 esterase YqiA YP_002272510.1 4024602 R 444450 CDS YP_002272511.1 209395917 6971626 complement(4025183..4026010) 1 NC_011353.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413; cyclic 3',5'-adenosine monophosphate phosphodiesterase 4026010 icc 6971626 icc Escherichia coli O157:H7 str. EC4115 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002272511.1 4025183 R 444450 CDS YP_002272512.1 209397815 6966784 complement(4026035..4026457) 1 NC_011353.1 identified by match to protein family HMM PF06853; hypothetical protein 4026457 6966784 ECH74115_4347 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272512.1 4026035 R 444450 CDS YP_002272513.1 209398913 6968806 complement(4026458..4027087) 1 NC_011353.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 4027087 nudF 6968806 nudF Escherichia coli O157:H7 str. EC4115 ADP-ribose pyrophosphatase NudF YP_002272513.1 4026458 R 444450 CDS YP_002272514.1 209400811 6970005 4027292..4028773 1 NC_011353.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 4028773 tolC 6970005 tolC Escherichia coli O157:H7 str. EC4115 outer membrane channel protein YP_002272514.1 4027292 D 444450 CDS YP_002272515.1 209397785 6972039 4028921..4029592 1 NC_011353.1 hypothetical protein 4029592 6972039 ECH74115_4350 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272515.1 4028921 D 444450 CDS YP_002272516.1 209397034 6968773 4029598..4030758 1 NC_011353.1 identified by match to protein family HMM PF03738; glutathionylspermidine synthase 4030758 6968773 ECH74115_4351 Escherichia coli O157:H7 str. EC4115 glutathionylspermidine synthase YP_002272516.1 4029598 D 444450 CDS YP_002272517.1 209396665 6967978 complement(4030796..4031611) 1 NC_011353.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 4031611 6967978 ECH74115_4352 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272517.1 4030796 R 444450 CDS YP_002272518.1 209395994 6967586 4031727..4032500 1 NC_011353.1 identified by match to protein family HMM PF02535; zinc transporter ZupT 4032500 zupT 6967586 zupT Escherichia coli O157:H7 str. EC4115 zinc transporter ZupT YP_002272518.1 4031727 D 444450 CDS YP_002272519.1 209397337 6966865 complement(4032558..4032728) 1 NC_011353.1 hypothetical protein 4032728 6966865 ECH74115_4354 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272519.1 4032558 R 444450 CDS YP_002272520.1 209397123 6968302 complement(4032990..4033643) 1 NC_011353.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 4033643 ribB 6968302 ribB Escherichia coli O157:H7 str. EC4115 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002272520.1 4032990 R 444450 CDS YP_002272521.1 209399214 6968072 4034017..4034316 1 NC_011353.1 identified by match to protein family HMM PF04380; hypothetical protein 4034316 6968072 ECH74115_4357 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272521.1 4034017 D 444450 CDS YP_002272522.1 209400405 6970324 complement(4034351..4034551) 1 NC_011353.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 4034551 glgS 6970324 glgS Escherichia coli O157:H7 str. EC4115 glycogen synthesis protein GlgS YP_002272522.1 4034351 R 444450 CDS YP_002272523.1 209396389 6971415 4035476..4037137 1 NC_011353.1 identified by match to protein family HMM PF01145; hypothetical protein 4037137 6971415 ECH74115_4360 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272523.1 4035476 D 444450 CDS YP_002272524.1 209395805 6972296 complement(4037931..4039364) 1 NC_011353.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 4039364 hldE 6972296 hldE Escherichia coli O157:H7 str. EC4115 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002272524.1 4037931 R 444450 CDS YP_002272525.1 209396456 6966661 complement(4039412..4042252) 1 NC_011353.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 4042252 glnE 6966661 glnE Escherichia coli O157:H7 str. EC4115 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002272525.1 4039412 R 444450 CDS YP_002272526.1 209395808 6967367 complement(4042275..4043576) 1 NC_011353.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235; adenylate cyclase 4043576 6967367 ECH74115_4365 Escherichia coli O157:H7 str. EC4115 adenylate cyclase YP_002272526.1 4042275 R 444450 CDS YP_002272527.1 209397759 6966664 complement(4043593..4043778) 1 NC_011353.1 identified by glimmer; hypothetical protein 4043778 6966664 ECH74115_4366 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272527.1 4043593 R 444450 CDS YP_002272528.1 209395813 6968746 4043818..4044438 1 NC_011353.1 signal transduction protein 4044438 6968746 ECH74115_4367 Escherichia coli O157:H7 str. EC4115 signal transduction protein YP_002272528.1 4043818 D 444450 CDS YP_002272529.1 209396575 6966669 4044502..4045740 1 NC_011353.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 4045740 cca 6966669 cca Escherichia coli O157:H7 str. EC4115 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002272529.1 4044502 D 444450 CDS YP_002272530.1 209399983 6967489 complement(4045921..4046742) 1 NC_011353.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 4046742 bacA 6967489 bacA Escherichia coli O157:H7 str. EC4115 undecaprenyl pyrophosphate phosphatase YP_002272530.1 4045921 R 444450 CDS YP_002272531.1 209397022 6971155 complement(4046833..4047201) 1 NC_011353.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 4047201 folB 6971155 folB Escherichia coli O157:H7 str. EC4115 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_002272531.1 4046833 R 444450 CDS YP_002272532.1 209397618 6967966 4047307..4047924 1 NC_011353.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 4047924 6967966 ECH74115_4371 Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate acyltransferase PlsY YP_002272532.1 4047307 D 444450 CDS YP_002272533.1 209395880 6968599 complement(4047937..4048869) 1 NC_011353.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 4048869 6968599 ECH74115_4372 Escherichia coli O157:H7 str. EC4115 transcriptional activator TtdR YP_002272533.1 4047937 R 444450 CDS YP_002272534.1 209396443 6966744 4049076..4049987 1 NC_011353.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 4049987 ddtA 6966744 ddtA Escherichia coli O157:H7 str. EC4115 tartrate dehydratase subunit alpha YP_002272534.1 4049076 D 444450 CDS YP_002272535.1 209400059 6967353 4049984..4050589 1 NC_011353.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 4050589 ttdB 6967353 ttdB Escherichia coli O157:H7 str. EC4115 L(+)-tartrate dehydratase subunit beta YP_002272535.1 4049984 D 444450 CDS YP_002272536.1 209400804 6971238 4050638..4052101 1 NC_011353.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; anion transporter 4052101 6971238 ECH74115_4375 Escherichia coli O157:H7 str. EC4115 anion transporter YP_002272536.1 4050638 D 444450 CDS YP_002272537.1 209400727 6972032 complement(4052144..4053157) 1 NC_011353.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 4053157 gcp 6972032 gcp Escherichia coli O157:H7 str. EC4115 DNA-binding/iron metalloprotein/AP endonuclease YP_002272537.1 4052144 R 444450 CDS YP_002272538.1 209396168 6971951 4053395..4053610 1 NC_011353.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 4053610 rpsU 6971951 rpsU Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S21 YP_002272538.1 4053395 D 444450 CDS YP_002272539.1 209396560 6967052 4053721..4055466 1 NC_011353.1 synthesizes RNA primers at the replication forks; DNA primase 4055466 dnaG 6967052 dnaG Escherichia coli O157:H7 str. EC4115 DNA primase YP_002272539.1 4053721 D 444450 CDS YP_002272540.1 209399452 6967952 4055661..4057502 1 NC_011353.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 4057502 rpoD 6967952 rpoD Escherichia coli O157:H7 str. EC4115 RNA polymerase sigma factor RpoD YP_002272540.1 4055661 D 444450 CDS YP_002272541.1 209400213 6970581 complement(4057581..4058087) 1 NC_011353.1 identified by match to protein family HMM PF03167; G/U mismatch-specific DNA glycosylase 4058087 mug 6970581 mug Escherichia coli O157:H7 str. EC4115 G/U mismatch-specific DNA glycosylase YP_002272541.1 4057581 R 444450 CDS YP_002272542.1 209400965 6972369 complement(4058341..4059105) 1 NC_011353.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021; siderophore-interacting protein 4059105 6972369 ECH74115_4383 Escherichia coli O157:H7 str. EC4115 siderophore-interacting protein YP_002272542.1 4058341 R 444450 CDS YP_002272543.1 209400481 6972204 4059393..4060016 1 NC_011353.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 4060016 6972204 ECH74115_4384 Escherichia coli O157:H7 str. EC4115 PadR family transcriptional regulator YP_002272543.1 4059393 D 444450 CDS YP_002272544.1 209395772 6971686 complement(4060170..4061690) 1 NC_011353.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229; aerotaxis receptor 4061690 aer 6971686 aer Escherichia coli O157:H7 str. EC4115 aerotaxis receptor YP_002272544.1 4060170 R 444450 CDS YP_002272545.1 209396983 6966628 complement(4061881..4062009) 1 NC_011353.1 identified by glimmer; hypothetical protein 4062009 6966628 ECH74115_4386 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272545.1 4061881 R 444450 CDS YP_002272546.1 209397233 6967924 4062108..4063487 1 NC_011353.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 4063487 ygjG 6967924 ygjG Escherichia coli O157:H7 str. EC4115 putrescine--2-oxoglutarate aminotransferase YP_002272546.1 4062108 D 444450 CDS YP_002272547.1 209399159 6968191 complement(4063529..4063861) 1 NC_011353.1 identified by match to protein family HMM PF01588; hypothetical protein 4063861 6968191 ECH74115_4388 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272547.1 4063529 R 444450 CDS YP_002272548.1 209399661 6970267 4064080..4065063 1 NC_011353.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; DNA-binding transcriptional repressor EbgR 4065063 ebgR 6970267 ebgR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor EbgR YP_002272548.1 4064080 D 444450 CDS YP_002272549.1 209400384 6970808 4065247..4068339 1 NC_011353.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 4068339 ebgA 6970808 ebgA Escherichia coli O157:H7 str. EC4115 cryptic beta-D-galactosidase subunit alpha YP_002272549.1 4065247 D 444450 CDS YP_002272550.1 209400844 6971585 4068336..4068785 1 NC_011353.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 4068785 ebgC 6971585 ebgC Escherichia coli O157:H7 str. EC4115 cryptic beta-D-galactosidase subunit beta YP_002272550.1 4068336 D 444450 CDS YP_002272551.1 209400233 6972075 4068848..4070281 1 NC_011353.1 identified by match to protein family HMM PF00324; amino acid permease family protein 4070281 6972075 ECH74115_4392 Escherichia coli O157:H7 str. EC4115 amino acid permease family protein YP_002272551.1 4068848 D 444450 CDS YP_002272552.1 209396676 6971423 4070415..4071485 1 NC_011353.1 hypothetical protein 4071485 6971423 ECH74115_4393 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272552.1 4070415 D 444450 CDS YP_002272553.1 209396102 6967597 4071502..4073853 1 NC_011353.1 glycosyl hydrolase 4073853 6967597 ECH74115_4394 Escherichia coli O157:H7 str. EC4115 glycosyl hydrolase YP_002272553.1 4071502 D 444450 CDS YP_002272554.1 209399199 6966981 4074379..4076397 1 NC_011353.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992; 2,4-dienoyl-CoA reductase 4076397 fadH 6966981 fadH Escherichia coli O157:H7 str. EC4115 2,4-dienoyl-CoA reductase YP_002272554.1 4074379 D 444450 CDS YP_002272555.1 209398621 6970307 complement(4076442..4076858) 1 NC_011353.1 identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein 4076858 6970307 ECH74115_4396 Escherichia coli O157:H7 str. EC4115 helix-turn-helix DNA-binding domain-containing protein YP_002272555.1 4076442 R 444450 CDS YP_002272556.1 209397417 6969684 complement(4076855..4077169) 1 NC_011353.1 hypothetical protein 4077169 6969684 ECH74115_4397 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272556.1 4076855 R 444450 CDS YP_002272557.1 209399561 6968385 complement(4077453..4078589) 1 NC_011353.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242; methyltransferase family protein 4078589 6968385 ECH74115_4398 Escherichia coli O157:H7 str. EC4115 methyltransferase family protein YP_002272557.1 4077453 R 444450 CDS YP_002272558.1 209398601 6970699 4078674..4079177 1 NC_011353.1 identified by match to protein family HMM PF01863; hypothetical protein 4079177 6970699 ECH74115_4399 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272558.1 4078674 D 444450 CDS YP_002272559.1 209400696 6969664 4079254..4079946 1 NC_011353.1 identified by match to protein family HMM PF02698; SanA protein 4079946 6969664 ECH74115_4400 Escherichia coli O157:H7 str. EC4115 SanA protein YP_002272559.1 4079254 D 444450 CDS YP_002272560.1 209396548 6971918 4080025..4081011 1 NC_011353.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase, NAD binding 4081011 6971918 ECH74115_4401 Escherichia coli O157:H7 str. EC4115 oxidoreductase, NAD binding YP_002272560.1 4080025 D 444450 CDS YP_002272561.1 209395978 6967462 4081295..4082260 1 NC_011353.1 identified by match to protein family HMM PF03741; protein Alx 4082260 alx 6967462 alx Escherichia coli O157:H7 str. EC4115 protein Alx YP_002272561.1 4081295 D 444450 CDS YP_002272562.1 209396321 6966847 4082659..4083903 1 NC_011353.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 4083903 sstT 6966847 sstT Escherichia coli O157:H7 str. EC4115 serine/threonine transporter SstT YP_002272562.1 4082659 D 444450 CDS YP_002272563.1 209397077 6967218 complement(4083908..4084459) 1 NC_011353.1 inner membrane protein 4084459 6967218 ECH74115_4405 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002272563.1 4083908 R 444450 CDS YP_002272564.1 209397307 6968023 complement(4084542..4086029) 1 NC_011353.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666; altronate dehydratase 4086029 uxaA 6968023 uxaA Escherichia coli O157:H7 str. EC4115 altronate dehydratase YP_002272564.1 4084542 R 444450 CDS YP_002272565.1 209397829 6968269 complement(4086044..4087456) 1 NC_011353.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 4087456 uxaC 6968269 uxaC Escherichia coli O157:H7 str. EC4115 glucuronate isomerase YP_002272565.1 4086044 R 444450 CDS YP_002272566.1 209397929 6968820 4087939..4089237 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; hexuronate transporter 4089237 exuT 6968820 exuT Escherichia coli O157:H7 str. EC4115 hexuronate transporter YP_002272566.1 4087939 D 444450 CDS YP_002272567.1 209398440 6968929 4089367..4090143 1 NC_011353.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 4090143 exuR 6968929 exuR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor ExuR YP_002272567.1 4089367 D 444450 CDS YP_002272568.1 209398716 6969492 4090488..4091150 1 NC_011353.1 identified by match to protein family HMM PF09335; inner membrane protein 4091150 6969492 ECH74115_4410 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002272568.1 4090488 D 444450 CDS YP_002272569.1 209400001 6969788 4091169..4091537 1 NC_011353.1 hypothetical protein 4091537 6969788 ECH74115_4411 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272569.1 4091169 D 444450 CDS YP_002272570.1 209399086 6971174 4091684..4092052 1 NC_011353.1 identified by match to protein family HMM PF06476; hypothetical protein 4092052 6971174 ECH74115_4412 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272570.1 4091684 D 444450 CDS YP_002272571.1 209400319 6970188 4092090..4092395 1 NC_011353.1 identified by match to protein family HMM PF05957; hypothetical protein 4092395 6970188 ECH74115_4413 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272571.1 4092090 D 444450 CDS YP_002272572.1 209400857 6971515 4092398..4092802 1 NC_011353.1 hypothetical protein 4092802 6971515 ECH74115_4414 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272572.1 4092398 D 444450 CDS YP_002272573.1 209396108 6972088 4092792..4093091 1 NC_011353.1 hypothetical protein 4093091 6972088 ECH74115_4415 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272573.1 4092792 D 444450 CDS YP_002272574.1 209397445 6966987 4093187..4093669 1 NC_011353.1 identified by match to protein family HMM PF07681; inner membrane protein YqjF 4093669 6966987 ECH74115_4416 Escherichia coli O157:H7 str. EC4115 inner membrane protein YqjF YP_002272574.1 4093187 D 444450 CDS YP_002272575.1 209397300 6968415 4093739..4094725 1 NC_011353.1 hypothetical protein 4094725 6968415 ECH74115_4417 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272575.1 4093739 D 444450 CDS YP_002272576.1 209399093 6968261 4095017..4095382 1 NC_011353.1 identified by match to protein family HMM PF05656; inner membrane protein YhaH 4095382 6968261 ECH74115_4418 Escherichia coli O157:H7 str. EC4115 inner membrane protein YhaH YP_002272576.1 4095017 D 444450 CDS YP_002272577.1 209397210 6970195 4095623..4095979 1 NC_011353.1 identified by match to protein family HMM PF05656; inner membrane protein 4095979 6970195 ECH74115_4419 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002272577.1 4095623 D 444450 CDS YP_002272578.1 209398065 6968168 complement(4096030..4096926) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4096926 6968168 ECH74115_4420 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002272578.1 4096030 R 444450 CDS YP_002272579.1 209396124 6969082 4097031..4097732 1 NC_011353.1 identified by match to protein family HMM PF02678; pirin family protein 4097732 6969082 ECH74115_4421 Escherichia coli O157:H7 str. EC4115 pirin family protein YP_002272579.1 4097031 D 444450 CDS YP_002272580.1 209400283 6967005 4097752..4097919 1 NC_011353.1 hypothetical protein 4097919 6967005 ECH74115_4422 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272580.1 4097752 D 444450 CDS YP_002272581.1 209399521 6971477 complement(4098053..4099363) 1 NC_011353.1 identified by match to protein family HMM PF06354; hypothetical protein 4099363 6971477 ECH74115_4423 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272581.1 4098053 R 444450 CDS YP_002272582.1 209397781 6970657 complement(4099391..4100722) 1 NC_011353.1 identified by match to protein family HMM TIGR00814; serine transporter family protein 4100722 6970657 ECH74115_4424 Escherichia coli O157:H7 str. EC4115 serine transporter family protein YP_002272582.1 4099391 R 444450 CDS YP_002272583.1 209397049 6968769 complement(4100997..4102367) 1 NC_011353.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine ammonia-lyase TdcG 4102367 tdcG 6968769 tdcG Escherichia coli O157:H7 str. EC4115 L-serine ammonia-lyase TdcG YP_002272583.1 4100997 R 444450 CDS YP_002272584.1 209397070 6967995 complement(4102433..4102822) 1 NC_011353.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; hypothetical protein 4102822 6967995 ECH74115_4426 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272584.1 4102433 R 444450 CDS YP_002272585.1 209396533 6968016 complement(4102836..4105130) 1 NC_011353.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 4105130 pflB1 6968016 pflB1 Escherichia coli O157:H7 str. EC4115 formate acetyltransferase YP_002272585.1 4102836 R 444450 CDS YP_002272586.1 209397576 6967446 complement(4105164..4106372) 1 NC_011353.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 4106372 tdcD 6967446 tdcD Escherichia coli O157:H7 str. EC4115 propionate/acetate kinase YP_002272586.1 4105164 R 444450 CDS YP_002272587.1 209398149 6968553 complement(4106398..4107729) 1 NC_011353.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 4107729 tdcC 6968553 tdcC Escherichia coli O157:H7 str. EC4115 threonine/serine transporter TdcC YP_002272587.1 4106398 R 444450 CDS YP_002272588.1 209396129 6969172 complement(4107751..4108740) 1 NC_011353.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 4108740 tdcB 6969172 tdcB Escherichia coli O157:H7 str. EC4115 threonine dehydratase YP_002272588.1 4107751 R 444450 CDS YP_002272589.1 209396695 6967011 complement(4108839..4109777) 1 NC_011353.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 4109777 tdcA 6967011 tdcA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator TdcA YP_002272589.1 4108839 R 444450 CDS YP_002272590.1 209399970 6967618 4109966..4110310 1 NC_011353.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 4110310 tdcR 6967618 tdcR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator TdcR YP_002272590.1 4109966 D 444450 CDS YP_002272591.1 209400554 6971141 4110566..4111105 1 NC_011353.1 identified by glimmer; hypothetical protein 4111105 6971141 ECH74115_4433 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272591.1 4110566 D 444450 CDS YP_002272592.1 209398424 6971763 4111127..4112314 1 NC_011353.1 hypothetical protein 4112314 6971763 ECH74115_4434 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272592.1 4111127 D 444450 CDS YP_002272593.1 209399632 6972284 complement(4112943..4114088) 1 NC_011353.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 4114088 garK 6972284 garK Escherichia coli O157:H7 str. EC4115 glycerate kinase YP_002272593.1 4112943 R 444450 CDS YP_002272594.1 209399219 6970777 complement(4114185..4115069) 1 NC_011353.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 4115069 garR 6970777 garR Escherichia coli O157:H7 str. EC4115 tartronate semialdehyde reductase YP_002272594.1 4114185 R 444450 CDS YP_002272595.1 209397366 6970329 complement(4115105..4115875) 1 NC_011353.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 4115875 garL 6970329 garL Escherichia coli O157:H7 str. EC4115 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_002272595.1 4115105 R 444450 CDS YP_002272596.1 209400778 6968333 complement(4115891..4117225) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; galactarate permease GarP 4117225 garP 6968333 garP Escherichia coli O157:H7 str. EC4115 galactarate permease GarP YP_002272596.1 4115891 R 444450 CDS YP_002272597.1 209400051 6972003 4117246..4117371 1 NC_011353.1 identified by glimmer; hypothetical protein 4117371 6972003 ECH74115_4440 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272597.1 4117246 D 444450 CDS YP_002272598.1 209396601 6971229 4117434..4117553 1 NC_011353.1 identified by glimmer; hypothetical protein 4117553 6971229 ECH74115_4441 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272598.1 4117434 D 444450 CDS YP_002272599.1 209395943 6967518 4117600..4119171 1 NC_011353.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248; galactarate dehydratase 4119171 garD 6967518 garD Escherichia coli O157:H7 str. EC4115 galactarate dehydratase YP_002272599.1 4117600 D 444450 CDS YP_002272600.1 209397800 6966810 4119515..4119655 1 NC_011353.1 HtrA suppressor protein SohA 4119655 sohA 6966810 sohA Escherichia coli O157:H7 str. EC4115 HtrA suppressor protein SohA YP_002272600.1 4119515 D 444450 CDS YP_002272601.1 209397155 6968789 4119655..4120119 1 NC_011353.1 hypothetical protein 4120119 6968789 ECH74115_4444 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272601.1 4119655 D 444450 CDS YP_002272602.1 209398713 6968107 complement(4120174..4120983) 1 NC_011353.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 4120983 6968107 ECH74115_4445 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator AgaR YP_002272602.1 4120174 R 444450 CDS YP_002272603.1 209398293 6969785 4121232..4122512 1 NC_011353.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; D-tagatose-bisphosphate aldolase non-catalytic subunit 4122512 6969785 ECH74115_4446 Escherichia coli O157:H7 str. EC4115 D-tagatose-bisphosphate aldolase non-catalytic subunit YP_002272603.1 4121232 D 444450 CDS YP_002272604.1 209400003 6969329 4122535..4123008 1 NC_011353.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4123008 agaV 6969329 agaV Escherichia coli O157:H7 str. EC4115 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002272604.1 4122535 D 444450 CDS YP_002272605.1 209399451 6971176 4123019..4123798 1 NC_011353.1 identified by match to protein family HMM PF03609; PTS system N-acetylgalactosamine-specific transporter subunit IIC 4123798 agaW 6971176 agaW Escherichia coli O157:H7 str. EC4115 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_002272605.1 4123019 D 444450 CDS YP_002272606.1 209400408 6970580 4123788..4124666 1 NC_011353.1 identified by match to protein family HMM PF03613; PTS system N-acetylgalactosamine-specific, IID component 4124666 agaE 6970580 agaE Escherichia coli O157:H7 str. EC4115 PTS system N-acetylgalactosamine-specific, IID component YP_002272606.1 4123788 D 444450 CDS YP_002272607.1 209399806 6971609 4124684..4125118 1 NC_011353.1 identified by match to protein family HMM PF03610; PTS system mannose/sorbose-specific transporter subunit IIA 4125118 agaF 6971609 agaF Escherichia coli O157:H7 str. EC4115 PTS system mannose/sorbose-specific transporter subunit IIA YP_002272607.1 4124684 D 444450 CDS YP_002272608.1 209399438 6970963 4125115..4126248 1 NC_011353.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 4126248 nagA1 6970963 nagA1 Escherichia coli O157:H7 str. EC4115 N-acetylglucosamine-6-phosphate deacetylase YP_002272608.1 4125115 D 444450 CDS YP_002272609.1 209398649 6970566 4126366..4126500 1 NC_011353.1 identified by glimmer; hypothetical protein 4126500 6970566 ECH74115_4452 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272609.1 4126366 D 444450 CDS YP_002272610.1 209400641 6969717 4126599..4127753 1 NC_011353.1 identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815; sugar isomerase 4127753 6969717 ECH74115_4453 Escherichia coli O157:H7 str. EC4115 sugar isomerase YP_002272610.1 4126599 D 444450 CDS YP_002272611.1 209399873 6971855 4127766..4128626 1 NC_011353.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 4128626 kbaY 6971855 kbaY Escherichia coli O157:H7 str. EC4115 tagatose-bisphosphate aldolase YP_002272611.1 4127766 D 444450 CDS YP_002272612.1 209399155 6971032 4128793..4129269 1 NC_011353.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4129269 agaB 6971032 agaB Escherichia coli O157:H7 str. EC4115 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002272612.1 4128793 D 444450 CDS YP_002272613.1 209398798 6969427 4130101..4130892 1 NC_011353.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 4130892 agaD 6969427 agaD Escherichia coli O157:H7 str. EC4115 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_002272613.1 4130101 D 444450 CDS YP_002272614.1 209398626 6970464 4132049..4132633 1 NC_011353.1 identified by match to protein family HMM PF00419; type 1 fimbrial protein 4132633 6970464 ECH74115_4460 Escherichia coli O157:H7 str. EC4115 type 1 fimbrial protein YP_002272614.1 4132049 D 444450 CDS YP_002272615.1 209400854 6969689 4132734..4133408 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; gram-negative pili assembly chaperone protein 4133408 6969689 ECH74115_4461 Escherichia coli O157:H7 str. EC4115 gram-negative pili assembly chaperone protein YP_002272615.1 4132734 D 444450 CDS YP_002272616.1 209400215 6972085 4133362..4135953 1 NC_011353.1 identified by match to protein family HMM PF00577; fimbrial usher family protein 4135953 6972085 ECH74115_4462 Escherichia coli O157:H7 str. EC4115 fimbrial usher family protein YP_002272616.1 4133362 D 444450 CDS YP_002272617.1 209397996 6972221 complement(4136740..4137600) 1 NC_011353.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase family protein 4137600 6972221 ECH74115_4465 Escherichia coli O157:H7 str. EC4115 tetrapyrrole methylase family protein YP_002272617.1 4136740 R 444450 CDS YP_002272618.1 209397195 6969007 4137665..4139701 1 NC_011353.1 identified by match to protein family HMM PF04348; lipoprotein 4139701 6969007 ECH74115_4466 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002272618.1 4137665 D 444450 CDS YP_002272619.1 209398652 6968151 4139659..4140054 1 NC_011353.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 4140054 6968151 ECH74115_4467 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272619.1 4139659 D 444450 CDS YP_002272620.1 209398082 6969721 4140074..4140664 1 NC_011353.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 4140664 diaA 6969721 diaA Escherichia coli O157:H7 str. EC4115 DnaA initiator-associating protein DiaA YP_002272620.1 4140074 D 444450 CDS YP_002272621.1 209395754 6969099 4140674..4141249 1 NC_011353.1 identified by match to protein family HMM PF04972; hypothetical protein 4141249 6969099 ECH74115_4469 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272621.1 4140674 D 444450 CDS YP_002272622.1 209396489 6966609 complement(4141363..4142403) 1 NC_011353.1 identified by match to protein family HMM PF03773; permease 4142403 6966609 ECH74115_4470 Escherichia coli O157:H7 str. EC4115 permease YP_002272622.1 4141363 R 444450 CDS YP_002272623.1 209396829 6967401 complement(4142476..4143111) 1 NC_011353.1 identified by match to protein family HMM PF01370; NAD dependent epimerase/dehydratase family protein 4143111 6967401 ECH74115_4471 Escherichia coli O157:H7 str. EC4115 NAD dependent epimerase/dehydratase family protein YP_002272623.1 4142476 R 444450 CDS YP_002272624.1 209400672 6967762 4143239..4143757 1 NC_011353.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; intracellular peptidase, PfpI family 4143757 6967762 ECH74115_4473 Escherichia coli O157:H7 str. EC4115 intracellular peptidase, PfpI family YP_002272624.1 4143239 D 444450 CDS YP_002272625.1 209395787 6971891 complement(4143737..4144180) 1 NC_011353.1 hypothetical protein 4144180 6971891 ECH74115_4472 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272625.1 4143737 R 444450 CDS YP_002272626.1 209398479 6966643 4144231..4144533 1 NC_011353.1 identified by match to protein family HMM PF01541; GIY-YIG nuclease superfamily protein 4144533 6966643 ECH74115_4475 Escherichia coli O157:H7 str. EC4115 GIY-YIG nuclease superfamily protein YP_002272626.1 4144231 D 444450 CDS YP_002272627.1 209400093 6969536 complement(4144520..4145023) 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 4145023 6969536 ECH74115_4474 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002272627.1 4144520 R 444450 CDS YP_002272628.1 209398889 6971275 complement(4145017..4145541) 1 NC_011353.1 identified by match to protein family HMM PF02036; sterol-binding protein 4145541 6971275 ECH74115_4476 Escherichia coli O157:H7 str. EC4115 sterol-binding protein YP_002272628.1 4145017 R 444450 CDS YP_002272629.1 209398259 6969978 4145750..4146745 1 NC_011353.1 identified by match to protein family HMM PF01136; U32 family peptidase 4146745 6969978 ECH74115_4477 Escherichia coli O157:H7 str. EC4115 U32 family peptidase YP_002272629.1 4145750 D 444450 CDS YP_002272630.1 209397518 6969291 4146754..4147632 1 NC_011353.1 identified by match to protein family HMM PF01136; U32 family peptidase 4147632 6969291 ECH74115_4478 Escherichia coli O157:H7 str. EC4115 U32 family peptidase YP_002272630.1 4146754 D 444450 CDS YP_002272631.1 209398705 6968491 4147713..4148720 1 NC_011353.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558; hypothetical protein 4148720 6968491 ECH74115_4479 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272631.1 4147713 D 444450 CDS YP_002272632.1 209399426 6969777 complement(4148837..4150081) 1 NC_011353.1 tryptophan transporter of high affinity; tryptophan permease 4150081 mtr 6969777 mtr Escherichia coli O157:H7 str. EC4115 tryptophan permease YP_002272632.1 4148837 R 444450 CDS YP_002272633.1 209400297 6970554 complement(4150235..4152124) 1 NC_011353.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 4152124 deaD 6970554 deaD Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase DeaD YP_002272633.1 4150235 R 444450 CDS YP_002272634.1 209399789 6971491 complement(4152304..4153188) 1 NC_011353.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 4153188 nlpI 6971491 nlpI Escherichia coli O157:H7 str. EC4115 lipoprotein NlpI YP_002272634.1 4152304 R 444450 CDS YP_002272635.1 209397723 6970946 complement(4153297..4155432) 1 NC_011353.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR03591; polynucleotide phosphorylase/polyadenylase 4155432 pnp 6970946 pnp Escherichia coli O157:H7 str. EC4115 polynucleotide phosphorylase/polyadenylase YP_002272635.1 4153297 R 444450 CDS YP_002272636.1 209395859 6972314 complement(4155679..4155948) 1 NC_011353.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 4155948 rpsO 6972314 rpsO Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S15 YP_002272636.1 4155679 R 444450 CDS YP_002272637.1 209399467 6966718 complement(4156097..4157041) 1 NC_011353.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 4157041 truB 6966718 truB Escherichia coli O157:H7 str. EC4115 tRNA pseudouridine synthase B YP_002272637.1 4156097 R 444450 CDS YP_002272638.1 209397218 6970599 complement(4157041..4157442) 1 NC_011353.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 4157442 rbfA 6970599 rbfA Escherichia coli O157:H7 str. EC4115 ribosome-binding factor A YP_002272638.1 4157041 R 444450 CDS YP_002272639.1 209400947 6968176 complement(4157607..4160279) 1 NC_011353.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 4160279 infB 6968176 infB Escherichia coli O157:H7 str. EC4115 translation initiation factor IF-2 YP_002272639.1 4157607 R 444450 CDS YP_002272640.1 209398727 6972185 complement(4160304..4161791) 1 NC_011353.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 4161791 nusA 6972185 nusA Escherichia coli O157:H7 str. EC4115 transcription elongation factor NusA YP_002272640.1 4160304 R 444450 CDS YP_002272641.1 209400717 6969801 complement(4161819..4162283) 1 NC_011353.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 4162283 6969801 ECH74115_4491 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272641.1 4161819 R 444450 CDS YP_002272642.1 209400149 6972404 4162694..4162816 1 NC_011353.1 hypothetical protein 4162816 6972404 ECH74115_4493 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272642.1 4162694 D 444450 CDS YP_002272643.1 209396632 6971335 4162902..4164245 1 NC_011353.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 4164245 argG 6971335 argG Escherichia coli O157:H7 str. EC4115 argininosuccinate synthase YP_002272643.1 4162902 D 444450 CDS YP_002272644.1 209395923 6967552 complement(4164253..4165770) 1 NC_011353.1 identified by match to protein family HMM PF00884; inner membrane protein yhbX 4165770 yhbX 6967552 yhbX Escherichia coli O157:H7 str. EC4115 inner membrane protein yhbX YP_002272644.1 4164253 R 444450 CDS YP_002272645.1 209400768 6972356 complement(4166438..4166770) 1 NC_011353.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 4166770 secG 6972356 secG Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecG YP_002272645.1 4166438 R 444450 CDS YP_002272646.1 209400076 6971993 complement(4166998..4168335) 1 NC_011353.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 4168335 glmM 6971993 glmM Escherichia coli O157:H7 str. EC4115 phosphoglucosamine mutase YP_002272646.1 4166998 R 444450 CDS YP_002272647.1 209397399 6971255 complement(4168328..4169176) 1 NC_011353.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 4169176 folP 6971255 folP Escherichia coli O157:H7 str. EC4115 dihydropteroate synthase YP_002272647.1 4168328 R 444450 CDS YP_002272648.1 209399479 6968365 complement(4169266..4171200) 1 NC_011353.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 4171200 hflB 6968365 hflB Escherichia coli O157:H7 str. EC4115 ATP-dependent metalloprotease YP_002272648.1 4169266 R 444450 CDS YP_002272649.1 209395973 6970612 complement(4171300..4171929) 1 NC_011353.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 4171929 rrmJ 6970612 rrmJ Escherichia coli O157:H7 str. EC4115 23S rRNA methyltransferase J YP_002272649.1 4171300 R 444450 CDS YP_002272650.1 209397701 6966842 4172055..4172348 1 NC_011353.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 4172348 6966842 ECH74115_4502 Escherichia coli O157:H7 str. EC4115 RNA-binding protein YhbY YP_002272650.1 4172055 D 444450 CDS YP_002272651.1 209400428 6968685 complement(4172504..4172980) 1 NC_011353.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 4172980 greA 6968685 greA Escherichia coli O157:H7 str. EC4115 transcription elongation factor GreA YP_002272651.1 4172504 R 444450 CDS YP_002272652.1 209399694 6971630 4173228..4174661 1 NC_011353.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 4174661 dacB 6971630 dacB Escherichia coli O157:H7 str. EC4115 D-alanyl-D-alanine carboxypeptidase YP_002272652.1 4173228 D 444450 CDS YP_002272653.1 209399332 6970844 complement(4174701..4175873) 1 NC_011353.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 4175873 obgE 6970844 obgE Escherichia coli O157:H7 str. EC4115 GTPase ObgE YP_002272653.1 4174701 R 444450 CDS YP_002272654.1 209400681 6970452 complement(4175889..4176854) 1 NC_011353.1 identified by match to protein family HMM PF00892; transporter 4176854 6970452 ECH74115_4506 Escherichia coli O157:H7 str. EC4115 transporter YP_002272654.1 4175889 R 444450 CDS YP_002272655.1 209397511 6971901 complement(4176981..4177238) 1 NC_011353.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 4177238 rpmA 6971901 rpmA Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L27 YP_002272655.1 4176981 R 444450 CDS YP_002272656.1 209399519 6968483 complement(4177259..4177570) 1 NC_011353.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 4177570 rplU 6968483 rplU Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L21 YP_002272656.1 4177259 R 444450 CDS YP_002272657.1 209396313 6970655 4177829..4178800 1 NC_011353.1 identified by match to protein family HMM PF00348; octaprenyl diphosphate synthase 4178800 ispB 6970655 ispB Escherichia coli O157:H7 str. EC4115 octaprenyl diphosphate synthase YP_002272657.1 4177829 D 444450 CDS YP_002272658.1 209397764 6967209 4179029..4179307 1 NC_011353.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 4179307 sfsB 6967209 sfsB Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator Nlp YP_002272658.1 4179029 D 444450 CDS YP_002272659.1 209399797 6968752 complement(4179355..4180614) 1 NC_011353.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4180614 murA 6968752 murA Escherichia coli O157:H7 str. EC4115 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002272659.1 4179355 R 444450 CDS YP_002272660.1 209396580 6970954 complement(4180669..4180938) 1 NC_011353.1 identified by match to protein family HMM PF01722; BolA/YrbA family protein 4180938 6970954 ECH74115_4512 Escherichia coli O157:H7 str. EC4115 BolA/YrbA family protein YP_002272660.1 4180669 R 444450 CDS YP_002272661.1 209397627 6967495 complement(4181083..4181376) 1 NC_011353.1 YrbB 4181376 yrbB 6967495 yrbB Escherichia coli O157:H7 str. EC4115 YrbB YP_002272661.1 4181083 R 444450 CDS YP_002272662.1 209396690 6968609 complement(4181376..4182011) 1 NC_011353.1 identified by match to protein family HMM PF05494; toluene tolerance protein Ttg2D 4182011 ttg2D 6968609 ttg2D Escherichia coli O157:H7 str. EC4115 toluene tolerance protein Ttg2D YP_002272662.1 4181376 R 444450 CDS YP_002272663.1 209399165 6967612 complement(4182030..4182581) 1 NC_011353.1 identified by match to protein family HMM PF02470; Mce family protein 4182581 6967612 ECH74115_4515 Escherichia coli O157:H7 str. EC4115 Mce family protein YP_002272663.1 4182030 R 444450 CDS YP_002272664.1 209399676 6970273 complement(4182586..4183368) 1 NC_011353.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056; toluene ABC transporter permease 4183368 6970273 ECH74115_4516 Escherichia coli O157:H7 str. EC4115 toluene ABC transporter permease YP_002272664.1 4182586 R 444450 CDS YP_002272665.1 209397948 6970824 complement(4183376..4184185) 1 NC_011353.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein 4184185 6970824 ECH74115_4517 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272665.1 4183376 R 444450 CDS YP_002272666.1 209398366 6968951 4184395..4185372 1 NC_011353.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 4185372 6968951 ECH74115_4518 Escherichia coli O157:H7 str. EC4115 calcium/sodium:proton antiporter YP_002272666.1 4184395 D 444450 CDS YP_002272667.1 209396758 6969409 4185386..4186372 1 NC_011353.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; D-arabinose 5-phosphate isomerase 4186372 kdsD 6969409 kdsD Escherichia coli O157:H7 str. EC4115 D-arabinose 5-phosphate isomerase YP_002272667.1 4185386 D 444450 CDS YP_002272668.1 209397194 6967685 4186393..4186959 1 NC_011353.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 4186959 kdsC 6967685 kdsC Escherichia coli O157:H7 str. EC4115 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002272668.1 4186393 D 444450 CDS YP_002272669.1 209400931 6968150 4186956..4187531 1 NC_011353.1 identified by match to protein family HMM PF06835; hypothetical protein 4187531 6968150 ECH74115_4521 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272669.1 4186956 D 444450 CDS YP_002272670.1 209396095 6972168 4187500..4188057 1 NC_011353.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 4188057 lptA 6972168 lptA Escherichia coli O157:H7 str. EC4115 lipopolysaccharide transport periplasmic protein LptA YP_002272670.1 4187500 D 444450 CDS YP_002272671.1 209398099 6966974 4188064..4188789 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 4188789 lptB 6966974 lptB Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272671.1 4188064 D 444450 CDS YP_002272672.1 209397246 6969117 4188837..4190270 1 NC_011353.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 4190270 rpoN 6969117 rpoN Escherichia coli O157:H7 str. EC4115 RNA polymerase factor sigma-54 YP_002272672.1 4188837 D 444450 CDS YP_002272673.1 209396867 6968204 4190293..4190580 1 NC_011353.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 4190580 yfiA 6968204 yfiA Escherichia coli O157:H7 str. EC4115 sigma(54) modulation protein YP_002272673.1 4190293 D 444450 CDS YP_002272674.1 209396068 6967802 4190698..4191189 1 NC_011353.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 4191189 ptsN 6967802 ptsN Escherichia coli O157:H7 str. EC4115 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_002272674.1 4190698 D 444450 CDS YP_002272675.1 209400426 6966947 4191235..4192089 1 NC_011353.1 identified by match to protein family HMM PF03668; hypothetical protein 4192089 6966947 ECH74115_4527 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272675.1 4191235 D 444450 CDS YP_002272676.1 209400866 6971628 4192086..4192358 1 NC_011353.1 identified by match to protein family HMM PF00381; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr 4192358 ptsO 6971628 ptsO Escherichia coli O157:H7 str. EC4115 PTS system phosphohistidinoprotein-hexose phosphotransferase Npr YP_002272676.1 4192086 D 444450 CDS YP_002272677.1 209398409 6972097 4192572..4193204 1 NC_011353.1 hypothetical protein 4193204 6972097 ECH74115_4530 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272677.1 4192572 D 444450 CDS YP_002272678.1 209399304 6969455 complement(4193201..4193929) 1 NC_011353.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 4193929 mtgA 6969455 mtgA Escherichia coli O157:H7 str. EC4115 monofunctional biosynthetic peptidoglycan transglycosylase YP_002272678.1 4193201 R 444450 CDS YP_002272679.1 209398524 6970421 complement(4193926..4194579) 1 NC_011353.1 identified by match to protein family HMM PF01965; isoprenoid biosynthesis protein 4194579 elbB 6970421 elbB Escherichia coli O157:H7 str. EC4115 isoprenoid biosynthesis protein YP_002272679.1 4193926 R 444450 CDS YP_002272680.1 209397926 6972292 complement(4194809..4197145) 1 NC_011353.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 4197145 arcB 6972292 arcB Escherichia coli O157:H7 str. EC4115 aerobic respiration control sensor protein ArcB YP_002272680.1 4194809 R 444450 CDS YP_002272681.1 209396579 6968926 complement(4197241..4198170) 1 NC_011353.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212; radical SAM protein 4198170 6968926 ECH74115_4534 Escherichia coli O157:H7 str. EC4115 radical SAM protein YP_002272681.1 4197241 R 444450 CDS YP_002272682.1 209396802 6967494 4198751..4203304 1 NC_011353.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 4203304 gltB 6967494 gltB Escherichia coli O157:H7 str. EC4115 glutamate synthase subunit alpha YP_002272682.1 4198751 D 444450 CDS YP_002272683.1 209399690 6967734 4203317..4204735 1 NC_011353.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 4204735 gltD 6967734 gltD Escherichia coli O157:H7 str. EC4115 glutamate synthase subunit beta YP_002272683.1 4203317 D 444450 CDS YP_002272684.1 209400395 6970840 4204919..4205968 1 NC_011353.1 identified by match to protein family HMM PF06250; hypothetical protein 4205968 6970840 ECH74115_4537 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272684.1 4204919 D 444450 CDS YP_002272685.1 209395846 6971596 complement(4206028..4206492) 1 NC_011353.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 4206492 6971596 ECH74115_4538 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272685.1 4206028 R 444450 CDS YP_002272686.1 209396911 6966703 complement(4206489..4207364) 1 NC_011353.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 4207364 6966703 ECH74115_4539 Escherichia coli O157:H7 str. EC4115 N-acetylmannosamine kinase YP_002272686.1 4206489 R 444450 CDS YP_002272687.1 209396728 6967849 complement(4207361..4208050) 1 NC_011353.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 4208050 6967849 ECH74115_4540 Escherichia coli O157:H7 str. EC4115 N-acetylmannosamine-6-phosphate 2-epimerase YP_002272687.1 4207361 R 444450 CDS YP_002272688.1 209397614 6967654 complement(4208098..4209588) 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891; sialic acid transporter 4209588 nanT1 6967654 nanT1 Escherichia coli O157:H7 str. EC4115 sialic acid transporter YP_002272688.1 4208098 R 444450 CDS YP_002272689.1 209398210 6968595 complement(4209697..4210590) 1 NC_011353.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 4210590 nanA 6968595 nanA Escherichia coli O157:H7 str. EC4115 N-acetylneuraminate lyase YP_002272689.1 4209697 R 444450 CDS YP_002272690.1 209399110 6969239 complement(4210712..4211494) 1 NC_011353.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 4211494 nanR 6969239 nanR Escherichia coli O157:H7 str. EC4115 transcriptional regulator NanR YP_002272690.1 4210712 R 444450 CDS YP_002272691.1 209398954 6970710 complement(4213282..4213779) 1 NC_011353.1 identified by match to protein family HMM PF04386; ClpXP protease specificity-enhancing factor 4213779 sspB 6970710 sspB Escherichia coli O157:H7 str. EC4115 ClpXP protease specificity-enhancing factor YP_002272691.1 4213282 R 444450 CDS YP_002272692.1 209398028 6970048 complement(4213785..4214423) 1 NC_011353.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 4214423 sspA 6970048 sspA Escherichia coli O157:H7 str. EC4115 stringent starvation protein A YP_002272692.1 4213785 R 444450 CDS YP_002272693.1 209396696 6969041 complement(4214818..4215210) 1 NC_011353.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 4215210 rpsI 6969041 rpsI Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S9 YP_002272693.1 4214818 R 444450 CDS YP_002272694.1 209395901 6967619 complement(4215226..4215654) 1 NC_011353.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 4215654 rplM 6967619 rplM Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L13 YP_002272694.1 4215226 R 444450 CDS YP_002272695.1 209400662 6966767 complement(4215873..4217000) 1 NC_011353.1 identified by match to protein family HMM PF03969; ATPase 4217000 6966767 ECH74115_4549 Escherichia coli O157:H7 str. EC4115 ATPase YP_002272695.1 4215873 R 444450 CDS YP_002272696.1 209399934 6971878 4217194..4217592 1 NC_011353.1 identified by match to protein family HMM PF06295; cytochrome d ubiquinol oxidase subunit III 4217592 6971878 ECH74115_4550 Escherichia coli O157:H7 str. EC4115 cytochrome d ubiquinol oxidase subunit III YP_002272696.1 4217194 D 444450 CDS YP_002272697.1 209399719 6971099 4217746..4219113 1 NC_011353.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; serine endoprotease 4219113 degQ 6971099 degQ Escherichia coli O157:H7 str. EC4115 serine endoprotease YP_002272697.1 4217746 D 444450 CDS YP_002272698.1 209400305 6970871 4219203..4220270 1 NC_011353.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038; serine endoprotease 4220270 degS 6970871 degS Escherichia coli O157:H7 str. EC4115 serine endoprotease YP_002272698.1 4219203 D 444450 CDS YP_002272699.1 209399586 6971500 complement(4220334..4221272) 1 NC_011353.1 oxidizes malate to oxaloacetate; malate dehydrogenase 4221272 mdh 6971500 mdh Escherichia coli O157:H7 str. EC4115 malate dehydrogenase YP_002272699.1 4220334 R 444450 CDS YP_002272700.1 209397870 6970727 4221707..4222177 1 NC_011353.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 4222177 argR 6970727 argR Escherichia coli O157:H7 str. EC4115 arginine repressor YP_002272700.1 4221707 D 444450 CDS YP_002272701.1 209395944 6968864 4222491..4222805 1 NC_011353.1 identified by match to protein family HMM PF07338; protein YcfR 4222805 ycfR 6968864 ycfR Escherichia coli O157:H7 str. EC4115 protein YcfR YP_002272701.1 4222491 D 444450 CDS YP_002272702.1 209396510 6966811 complement(4222861..4223133) 1 NC_011353.1 hypothetical protein 4223133 6966811 ECH74115_4556 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272702.1 4222861 R 444450 CDS YP_002272703.1 209400336 6967422 complement(4223225..4225192) 1 NC_011353.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 4225192 aaeB 6967422 aaeB Escherichia coli O157:H7 str. EC4115 p-hydroxybenzoic acid efflux subunit AaeB YP_002272703.1 4223225 R 444450 CDS YP_002272704.1 209396247 6971533 complement(4225198..4226127) 1 NC_011353.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 4226127 aaeA 6971533 aaeA Escherichia coli O157:H7 str. EC4115 p-hydroxybenzoic acid efflux subunit AaeA YP_002272704.1 4225198 R 444450 CDS YP_002272705.1 209399458 6967139 complement(4226135..4226407) 1 NC_011353.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 4226407 aaeX 6967139 aaeX Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272705.1 4226135 R 444450 CDS YP_002272706.1 209400033 6970588 4226521..4227450 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 4227450 aaeR 6970588 aaeR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YP_002272706.1 4226521 D 444450 CDS YP_002272707.1 209398830 6971208 complement(4227584..4229029) 1 NC_011353.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 4229029 tldD 6971208 tldD Escherichia coli O157:H7 str. EC4115 protease TldD YP_002272707.1 4227584 R 444450 CDS YP_002272708.1 209398580 6969913 complement(4229185..4232985) 1 NC_011353.1 identified by match to protein family HMM TIGR02099; hypothetical protein 4232985 6969913 ECH74115_4562 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272708.1 4229185 R 444450 CDS YP_002272709.1 209396614 6969641 complement(4233053..4234522) 1 NC_011353.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 4234522 cafA 6969641 cafA Escherichia coli O157:H7 str. EC4115 ribonuclease G YP_002272709.1 4233053 R 444450 CDS YP_002272710.1 209400628 6967533 complement(4234512..4235105) 1 NC_011353.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 4235105 maf1 6967533 maf1 Escherichia coli O157:H7 str. EC4115 Maf-like protein YP_002272710.1 4234512 R 444450 CDS YP_002272711.1 209397202 6971841 complement(4235114..4235602) 1 NC_011353.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 4235602 mreD 6971841 mreD Escherichia coli O157:H7 str. EC4115 rod shape-determining protein MreD YP_002272711.1 4235114 R 444450 CDS YP_002272712.1 209397967 6968158 complement(4235602..4236705) 1 NC_011353.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 4236705 mreC 6968158 mreC Escherichia coli O157:H7 str. EC4115 rod shape-determining protein MreC YP_002272712.1 4235602 R 444450 CDS YP_002272713.1 209395744 6968973 complement(4236771..4237814) 1 NC_011353.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 4237814 mreB 6968973 mreB Escherichia coli O157:H7 str. EC4115 rod shape-determining protein MreB YP_002272713.1 4236771 R 444450 CDS YP_002272714.1 209396452 6966599 complement(4238119..4240059) 1 NC_011353.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 4240059 6966599 ECH74115_4568 Escherichia coli O157:H7 str. EC4115 regulatory protein CsrD YP_002272714.1 4238119 R 444450 CDS YP_002272715.1 209400900 6967363 4240211..4241185 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823; quinone oxidoreductase, YhdH family 4241185 6967363 ECH74115_4569 Escherichia coli O157:H7 str. EC4115 quinone oxidoreductase, YhdH family YP_002272715.1 4240211 D 444450 CDS YP_002272716.1 209396841 6972135 4241222..4241386 1 NC_011353.1 hypothetical protein 4241386 6972135 ECH74115_4570 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272716.1 4241222 D 444450 CDS YP_002272717.1 209400000 6970372 4242163..4242633 1 NC_011353.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 4242633 accB 6970372 accB Escherichia coli O157:H7 str. EC4115 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002272717.1 4242163 D 444450 CDS YP_002272718.1 209396842 6971173 4242644..4243993 1 NC_011353.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 4243993 accC 6971173 accC Escherichia coli O157:H7 str. EC4115 acetyl-CoA carboxylase biotin carboxylase subunit YP_002272718.1 4242644 D 444450 CDS YP_002272719.1 209399721 6967775 4244102..4244344 1 NC_011353.1 identified by match to protein family HMM PF06196; hypothetical protein 4244344 6967775 ECH74115_4574 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272719.1 4244102 D 444450 CDS YP_002272720.1 209399022 6970874 4244334..4245785 1 NC_011353.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 4245785 panF 6970874 panF Escherichia coli O157:H7 str. EC4115 sodium/panthothenate symporter YP_002272720.1 4244334 D 444450 CDS YP_002272721.1 209399574 6970122 4245797..4246678 1 NC_011353.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 4246678 prmA 6970122 prmA Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L11 methyltransferase YP_002272721.1 4245797 D 444450 CDS YP_002272722.1 209396246 6970713 4247007..4247972 1 NC_011353.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 4247972 dusB 6970713 dusB Escherichia coli O157:H7 str. EC4115 tRNA-dihydrouridine synthase B YP_002272722.1 4247007 D 444450 CDS YP_002272723.1 209398309 6967138 4247998..4248294 1 NC_011353.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 4248294 fis 6967138 fis Escherichia coli O157:H7 str. EC4115 DNA-binding protein Fis YP_002272723.1 4247998 D 444450 CDS YP_002272724.1 209400072 6969346 4248379..4249263 1 NC_011353.1 identified by match to protein family HMM PF01555; methyltransferase 4249263 6969346 ECH74115_4579 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002272724.1 4248379 D 444450 CDS YP_002272725.1 209396821 6971251 4249413..4249526 1 NC_011353.1 hypothetical protein 4249526 6971251 ECH74115_4580 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272725.1 4249413 D 444450 CDS YP_002272726.1 209398326 6967753 complement(4249529..4250191) 1 NC_011353.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08361; DNA-binding transcriptional regulator EnvR 4250191 6967753 ECH74115_4581 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator EnvR YP_002272726.1 4249529 R 444450 CDS YP_002272727.1 209399035 6969364 4250590..4251747 1 NC_011353.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein E 4251747 acrE 6969364 acrE Escherichia coli O157:H7 str. EC4115 acriflavine resistance protein E YP_002272727.1 4250590 D 444450 CDS YP_002272728.1 209396069 6970893 4255161..4255382 1 NC_011353.1 lipoprotein 4255382 6970893 ECH74115_4585 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002272728.1 4255161 D 444450 CDS YP_002272729.1 209396773 6966948 complement(4255430..4255576) 1 NC_011353.1 identified by glimmer; hypothetical protein 4255576 6966948 ECH74115_4586 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272729.1 4255430 R 444450 CDS YP_002272730.1 209397538 6967702 4255813..4256838 1 NC_011353.1 amino acid ABC transporter periplasmic amino acid-binding protein 4256838 6967702 ECH74115_4587 Escherichia coli O157:H7 str. EC4115 amino acid ABC transporter periplasmic amino acid-binding protein YP_002272730.1 4255813 D 444450 CDS YP_002272731.1 209398125 6968512 4256906..4258087 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 4258087 6968512 ECH74115_4588 Escherichia coli O157:H7 str. EC4115 amino acid ABC transporter permease YP_002272731.1 4256906 D 444450 CDS YP_002272732.1 209398401 6969146 4258097..4259185 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; general L-amino acid transport system permease AapM 4259185 6969146 ECH74115_4589 Escherichia coli O157:H7 str. EC4115 general L-amino acid transport system permease AapM YP_002272732.1 4258097 D 444450 CDS YP_002272733.1 209399291 6969447 4259211..4259537 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF01527; IS629, transposase orfA 4259537 6969447 ECH74115_4590 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfA YP_002272733.1 4259211 D 444450 CDS YP_002272734.1 209399442 6970407 4259534..4260424 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00665; IS629, transposase orfB 4260424 6970407 ECH74115_4591 Escherichia coli O157:H7 str. EC4115 IS629, transposase orfB YP_002272734.1 4259534 D 444450 CDS YP_002272735.1 209400549 6970570 4260521..4261279 1 NC_011353.1 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 4261279 6970570 ECH74115_4592 Escherichia coli O157:H7 str. EC4115 amino acid ABC transporter ATP-binding protein YP_002272735.1 4260521 D 444450 CDS YP_002272736.1 209400737 6972265 4267328..4267882 1 NC_011353.1 hypothetical protein 4267882 6972265 ECH74115_4603 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272736.1 4267328 D 444450 CDS YP_002272737.1 209396339 6971962 complement(4267858..4268031) 1 NC_011353.1 identified by match to protein family HMM PF07369; hypothetical protein 4268031 6971962 ECH74115_4602 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272737.1 4267858 R 444450 CDS YP_002272738.1 209397484 6967240 complement(4268112..4268930) 1 NC_011353.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 4268930 aroE 6967240 aroE Escherichia coli O157:H7 str. EC4115 shikimate 5-dehydrogenase YP_002272738.1 4268112 R 444450 CDS YP_002272739.1 209396523 6968455 complement(4268935..4269507) 1 NC_011353.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 4269507 6968455 ECH74115_4605 Escherichia coli O157:H7 str. EC4115 ribosome maturation factor YP_002272739.1 4268935 R 444450 CDS YP_002272740.1 209398594 6967436 complement(4269512..4270054) 1 NC_011353.1 identified by match to protein family HMM PF01396; topoisomerase DNA-binding C4 zinc finger domain-containing protein 4270054 6967436 ECH74115_4606 Escherichia coli O157:H7 str. EC4115 topoisomerase DNA-binding C4 zinc finger domain-containing protein YP_002272740.1 4269512 R 444450 CDS YP_002272741.1 209397692 6969655 complement(4270083..4270556) 1 NC_011353.1 identified by match to protein family HMM PF04361; hypothetical protein 4270556 smg 6969655 smg Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272741.1 4270083 R 444450 CDS YP_002272742.1 209395952 6968675 complement(4270528..4271652) 1 NC_011353.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 4271652 dprA 6968675 dprA Escherichia coli O157:H7 str. EC4115 DNA protecting protein DprA YP_002272742.1 4270528 R 444450 CDS YP_002272743.1 209400361 6966819 4271782..4272291 1 NC_011353.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4272291 def 6966819 def Escherichia coli O157:H7 str. EC4115 peptide deformylase YP_002272743.1 4271782 D 444450 CDS YP_002272744.1 209397164 6971559 4272306..4273253 1 NC_011353.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 4273253 fmt 6971559 fmt Escherichia coli O157:H7 str. EC4115 methionyl-tRNA formyltransferase YP_002272744.1 4272306 D 444450 CDS YP_002272745.1 209396232 6968117 4273299..4274588 1 NC_011353.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 4274588 rsmB 6968117 rsmB Escherichia coli O157:H7 str. EC4115 16S rRNA methyltransferase B YP_002272745.1 4273299 D 444450 CDS YP_002272746.1 209397574 6967122 4274610..4275986 1 NC_011353.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 4275986 trkA 6967122 trkA Escherichia coli O157:H7 str. EC4115 potassium transporter peripheral membrane protein YP_002272746.1 4274610 D 444450 CDS YP_002272747.1 209398454 6968550 4276116..4276526 1 NC_011353.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 4276526 mscL 6968550 mscL Escherichia coli O157:H7 str. EC4115 large-conductance mechanosensitive channel YP_002272747.1 4276116 D 444450 CDS YP_002272748.1 209400338 6969507 complement(4276797..4277222) 1 NC_011353.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 4277222 zntR 6969507 zntR Escherichia coli O157:H7 str. EC4115 zinc-responsive transcriptional regulator YP_002272748.1 4276797 R 444450 CDS YP_002272749.1 209399921 6971535 complement(4277233..4277601) 1 NC_011353.1 identified by match to protein family HMM PF09350; hypothetical protein 4277601 6971535 ECH74115_4615 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272749.1 4277233 R 444450 CDS YP_002272750.1 209399907 6971085 complement(4277708..4278091) 1 NC_011353.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 4278091 rplQ 6971085 rplQ Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L17 YP_002272750.1 4277708 R 444450 CDS YP_002272751.1 209396788 6971071 complement(4278132..4279121) 1 NC_011353.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 4279121 rpoA 6971071 rpoA Escherichia coli O157:H7 str. EC4115 DNA-directed RNA polymerase subunit alpha YP_002272751.1 4278132 R 444450 CDS YP_002272752.1 209396300 6967719 complement(4279147..4279767) 1 NC_011353.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 4279767 rpsD 6967719 rpsD Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S4 YP_002272752.1 4279147 R 444450 CDS YP_002272753.1 209398081 6967195 complement(4279801..4280190) 1 NC_011353.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 4280190 rpsK 6967195 rpsK Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S11 YP_002272753.1 4279801 R 444450 CDS YP_002272754.1 209398653 6969098 complement(4280207..4280563) 1 NC_011353.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 4280563 rpsM 6969098 rpsM Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S13 YP_002272754.1 4280207 R 444450 CDS YP_002272755.1 209400203 6969722 complement(4280710..4280826) 1 NC_011353.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 4280826 rpmJ 6969722 rpmJ Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L36 YP_002272755.1 4280710 R 444450 CDS YP_002272756.1 209400982 6971391 complement(4280858..4282189) 1 NC_011353.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 4282189 secY 6971391 secY Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecY YP_002272756.1 4280858 R 444450 CDS YP_002272757.1 209396084 6972224 complement(4282197..4282631) 1 NC_011353.1 late assembly protein; 50S ribosomal protein L15 4282631 rplO 6972224 rplO Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L15 YP_002272757.1 4282197 R 444450 CDS YP_002272758.1 209397407 6966963 complement(4282635..4282814) 1 NC_011353.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 4282814 rpmD 6966963 rpmD Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L30 YP_002272758.1 4282635 R 444450 CDS YP_002272759.1 209398165 6968373 complement(4282818..4283321) 1 NC_011353.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 4283321 rpsE 6968373 rpsE Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S5 YP_002272759.1 4282818 R 444450 CDS YP_002272760.1 209397928 6969190 complement(4283336..4283689) 1 NC_011353.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 4283689 rplR 6969190 rplR Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L18 YP_002272760.1 4283336 R 444450 CDS YP_002272761.1 209398662 6968928 complement(4283699..4284232) 1 NC_011353.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 4284232 rplF 6968928 rplF Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L6 YP_002272761.1 4283699 R 444450 CDS YP_002272762.1 209400002 6969732 complement(4284245..4284637) 1 NC_011353.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 4284637 rpsH 6969732 rpsH Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S8 YP_002272762.1 4284245 R 444450 CDS YP_002272763.1 209400585 6971175 complement(4284671..4284976) 1 NC_011353.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 4284976 rpsN 6971175 rpsN Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S14 YP_002272763.1 4284671 R 444450 CDS YP_002272764.1 209396175 6971796 complement(4284991..4285530) 1 NC_011353.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 4285530 rplE 6971796 rplE Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L5 YP_002272764.1 4284991 R 444450 CDS YP_002272765.1 209397708 6967061 complement(4285545..4285859) 1 NC_011353.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 4285859 rplX 6967061 rplX Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L24 YP_002272765.1 4285545 R 444450 CDS YP_002272766.1 209397559 6968692 complement(4285870..4286241) 1 NC_011353.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 4286241 rplN 6968692 rplN Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L14 YP_002272766.1 4285870 R 444450 CDS YP_002272767.1 209397109 6968535 complement(4286406..4286660) 1 NC_011353.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 4286660 rpsQ 6968535 rpsQ Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S17 YP_002272767.1 4286406 R 444450 CDS YP_002272768.1 209398731 6968058 complement(4286660..4286851) 1 NC_011353.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 4286851 rpmC 6968058 rpmC Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L29 YP_002272768.1 4286660 R 444450 CDS YP_002272769.1 209401001 6969805 complement(4286851..4287261) 1 NC_011353.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 4287261 rplP 6969805 rplP Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L16 YP_002272769.1 4286851 R 444450 CDS YP_002272770.1 209400495 6972243 complement(4287274..4287975) 1 NC_011353.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 4287975 rpsC 6972243 rpsC Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S3 YP_002272770.1 4287274 R 444450 CDS YP_002272771.1 209400254 6971700 complement(4287993..4288325) 1 NC_011353.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 4288325 rplV 6971700 rplV Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L22 YP_002272771.1 4287993 R 444450 CDS YP_002272772.1 209396364 6971445 complement(4288340..4288618) 1 NC_011353.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 4288618 rpsS 6971445 rpsS Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S19 YP_002272772.1 4288340 R 444450 CDS YP_002272773.1 209395900 6967266 complement(4288635..4289456) 1 NC_011353.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 4289456 rplB 6967266 rplB Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L2 YP_002272773.1 4288635 R 444450 CDS YP_002272774.1 209400779 6966766 complement(4289474..4289776) 1 NC_011353.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 4289776 rplW 6966766 rplW Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L23 YP_002272774.1 4289474 R 444450 CDS YP_002272775.1 209398551 6972004 complement(4289773..4290378) 1 NC_011353.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 4290378 rplD 6972004 rplD Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L4 YP_002272775.1 4289773 R 444450 CDS YP_002272776.1 209398982 6969611 complement(4290389..4291018) 1 NC_011353.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 4291018 rplC 6969611 rplC Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L3 YP_002272776.1 4290389 R 444450 CDS YP_002272777.1 209399386 6970081 complement(4291051..4291362) 1 NC_011353.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 4291362 rpsJ 6970081 rpsJ Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S10 YP_002272777.1 4291051 R 444450 CDS YP_002272778.1 209398150 6970511 4291741..4292208 1 NC_011353.1 peptidase, A24 (type IV prepilin peptidase) family 4292208 6970511 ECH74115_4646 Escherichia coli O157:H7 str. EC4115 peptidase, A24 (type IV prepilin peptidase) family YP_002272778.1 4291741 D 444450 CDS YP_002272779.1 209397243 6969173 complement(4292205..4292681) 1 NC_011353.1 iron storage protein; bacterioferritin 4292681 bfr 6969173 bfr Escherichia coli O157:H7 str. EC4115 bacterioferritin YP_002272779.1 4292205 R 444450 CDS YP_002272780.1 209395873 6968201 complement(4292754..4292948) 1 NC_011353.1 identified by match to protein family HMM PF04324; bacterioferritin-associated ferredoxin 4292948 bfd 6968201 bfd Escherichia coli O157:H7 str. EC4115 bacterioferritin-associated ferredoxin YP_002272780.1 4292754 R 444450 CDS YP_002272781.1 209396629 6966737 complement(4293131..4294315) 1 NC_011353.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4294315 tuf2 6966737 tuf2 Escherichia coli O157:H7 str. EC4115 elongation factor Tu YP_002272781.1 4293131 R 444450 CDS YP_002272782.1 209397010 6967549 complement(4294386..4296500) 1 NC_011353.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 4296500 fusA 6967549 fusA Escherichia coli O157:H7 str. EC4115 elongation factor G YP_002272782.1 4294386 R 444450 CDS YP_002272783.1 209397949 6967953 complement(4296597..4297067) 1 NC_011353.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 4297067 rpsG 6967953 rpsG Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S7 YP_002272783.1 4296597 R 444450 CDS YP_002272784.1 209395851 6968952 complement(4297164..4297538) 1 NC_011353.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 4297538 rpsL 6968952 rpsL Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S12 YP_002272784.1 4297164 R 444450 CDS YP_002272785.1 209399822 6966709 complement(4297664..4297951) 1 NC_011353.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 4297951 dsrH 6966709 dsrH Escherichia coli O157:H7 str. EC4115 sulfur transfer complex subunit TusB YP_002272785.1 4297664 R 444450 CDS YP_002272786.1 209400382 6970979 complement(4297959..4298318) 1 NC_011353.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 4298318 tusC 6970979 tusC Escherichia coli O157:H7 str. EC4115 sulfur relay protein TusC YP_002272786.1 4297959 R 444450 CDS YP_002272787.1 209396017 6971582 complement(4298318..4298704) 1 NC_011353.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 4298704 tusD 6971582 tusD Escherichia coli O157:H7 str. EC4115 sulfur transfer complex subunit TusD YP_002272787.1 4298318 R 444450 CDS YP_002272788.1 209396553 6966890 complement(4298704..4299426) 1 NC_011353.1 identified by match to protein family HMM PF08348; hypothetical protein 4299426 6966890 ECH74115_4655 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272788.1 4298704 R 444450 CDS YP_002272789.1 209397438 6967467 complement(4299593..4300405) 1 NC_011353.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 4300405 fkpA 6967467 fkpA Escherichia coli O157:H7 str. EC4115 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002272789.1 4299593 R 444450 CDS YP_002272790.1 209398322 6968408 4300626..4300844 1 NC_011353.1 identified by match to protein family HMM PF04102; hypothetical protein 4300844 6968408 ECH74115_4657 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272790.1 4300626 D 444450 CDS YP_002272791.1 209398872 6969360 complement(4300893..4301483) 1 NC_011353.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 4301483 slyD 6969360 slyD Escherichia coli O157:H7 str. EC4115 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002272791.1 4300893 R 444450 CDS YP_002272792.1 209398452 6969958 complement(4301578..4301778) 1 NC_011353.1 identified by match to protein family HMM PF09526; match to protein family HMM TIGR02443; hypothetical protein 4301778 6969958 ECH74115_4659 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272792.1 4301578 R 444450 CDS YP_002272793.1 209397369 6970130 complement(4303593..4304147) 1 NC_011353.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 4304147 kefG 6970130 kefG Escherichia coli O157:H7 str. EC4115 glutathione-regulated potassium-efflux system ancillary protein KefG YP_002272793.1 4303593 R 444450 CDS YP_002272794.1 209398585 6968336 4304275..4306188 1 NC_011353.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 4306188 6968336 ECH74115_4662 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272794.1 4304275 D 444450 CDS YP_002272795.1 209400340 6969646 4306188..4307210 1 NC_011353.1 identified by match to protein family HMM PF00561; hydrolase 4307210 6969646 ECH74115_4663 Escherichia coli O157:H7 str. EC4115 hydrolase YP_002272795.1 4306188 D 444450 CDS YP_002272796.1 209399742 6971537 4307204..4307422 1 NC_011353.1 identified by match to protein family HMM PF06794; hypothetical protein 4307422 6971537 ECH74115_4664 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272796.1 4307204 D 444450 CDS YP_002272797.1 209396520 6970897 4307476..4308345 1 NC_011353.1 identified by match to protein family HMM PF00485; phosphoribulokinase/uridine kinase family protein 4308345 6970897 ECH74115_4665 Escherichia coli O157:H7 str. EC4115 phosphoribulokinase/uridine kinase family protein YP_002272797.1 4307476 D 444450 CDS YP_002272798.1 209396265 6967433 complement(4308400..4308804) 1 NC_011353.1 identified by match to protein family HMM PF02566; hypothetical protein 4308804 6967433 ECH74115_4666 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272798.1 4308400 R 444450 CDS YP_002272799.1 209398039 6967158 4309106..4309738 1 NC_011353.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 4309738 crp 6967158 crp Escherichia coli O157:H7 str. EC4115 cAMP-regulatory protein YP_002272799.1 4309106 D 444450 CDS YP_002272800.1 209397460 6969052 4309789..4311879 1 NC_011353.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667; YccS/YhfK family integral membrane protein 4311879 6969052 ECH74115_4668 Escherichia coli O157:H7 str. EC4115 YccS/YhfK family integral membrane protein YP_002272800.1 4309789 D 444450 CDS YP_002272801.1 209396810 6968431 complement(4311946..4313166) 1 NC_011353.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 4313166 argD 6968431 argD Escherichia coli O157:H7 str. EC4115 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase YP_002272801.1 4311946 R 444450 CDS YP_002272802.1 209396064 6967742 complement(4313252..4313815) 1 NC_011353.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 4313815 pabA 6967742 pabA Escherichia coli O157:H7 str. EC4115 para-aminobenzoate synthase component II YP_002272802.1 4313252 R 444450 CDS YP_002272803.1 209398302 6966941 complement(4313847..4314449) 1 NC_011353.1 identified by match to protein family HMM PF02661; cell filamentation protein Fic 4314449 fic 6966941 fic Escherichia coli O157:H7 str. EC4115 cell filamentation protein Fic YP_002272803.1 4313847 R 444450 CDS YP_002272804.1 209397201 6969338 complement(4314439..4314606) 1 NC_011353.1 hypothetical protein 4314606 6969338 ECH74115_4672 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272804.1 4314439 R 444450 CDS YP_002272805.1 209400102 6968157 complement(4314711..4315283) 1 NC_011353.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase A 4315283 ppiA 6968157 ppiA Escherichia coli O157:H7 str. EC4115 peptidyl-prolyl cis-trans isomerase A YP_002272805.1 4314711 R 444450 CDS YP_002272806.1 209399422 6971284 complement(4315427..4315573) 1 NC_011353.1 identified by glimmer; hypothetical protein 4315573 6971284 ECH74115_4674 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272806.1 4315427 R 444450 CDS YP_002272807.1 209396309 6970550 4315554..4316735 1 NC_011353.1 identified by match to protein family HMM PF07690; hypothetical protein 4316735 tsgA 6970550 tsgA Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272807.1 4315554 D 444450 CDS YP_002272808.1 209400899 6967204 4316997..4319540 1 NC_011353.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; nitrite reductase [NAD(P)H], large subunit 4319540 nirB 6967204 nirB Escherichia coli O157:H7 str. EC4115 nitrite reductase [NAD(P)H], large subunit YP_002272808.1 4316997 D 444450 CDS YP_002272809.1 209397331 6972134 4319537..4319863 1 NC_011353.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 4319863 nirD 6972134 nirD Escherichia coli O157:H7 str. EC4115 nitrite reductase small subunit YP_002272809.1 4319537 D 444450 CDS YP_002272810.1 209396408 6968296 4319989..4320795 1 NC_011353.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 4320795 nirC 6968296 nirC Escherichia coli O157:H7 str. EC4115 nitrite transporter NirC YP_002272810.1 4319989 D 444450 CDS YP_002272811.1 209397180 6967315 4320814..4322187 1 NC_011353.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 4322187 cysG 6967315 cysG Escherichia coli O157:H7 str. EC4115 siroheme synthase YP_002272811.1 4320814 D 444450 CDS YP_002272812.1 209396426 6968134 4322442..4322609 1 NC_011353.1 lipoprotein 4322609 6968134 ECH74115_4680 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002272812.1 4322442 D 444450 CDS YP_002272813.1 209399353 6967333 complement(4322628..4322759) 1 NC_011353.1 identified by glimmer; hypothetical protein 4322759 6967333 ECH74115_4681 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272813.1 4322628 R 444450 CDS YP_002272814.1 209396621 6970474 4322905..4324242 1 NC_011353.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; fructoselysine transporter 4324242 frlA 6970474 frlA Escherichia coli O157:H7 str. EC4115 fructoselysine transporter YP_002272814.1 4322905 D 444450 CDS YP_002272815.1 209396714 6967540 4324263..4325285 1 NC_011353.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 4325285 frlB 6967540 frlB Escherichia coli O157:H7 str. EC4115 fructoselysine-6-P-deglycase YP_002272815.1 4324263 D 444450 CDS YP_002272816.1 209400169 6967639 4325336..4326163 1 NC_011353.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 4326163 6967639 ECH74115_4684 Escherichia coli O157:H7 str. EC4115 fructoselysine 3-epimerase YP_002272816.1 4325336 D 444450 CDS YP_002272817.1 209399098 6969402 4326982..4327779 1 NC_011353.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 4327779 frlR 6969402 frlR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator FrlR YP_002272817.1 4326982 D 444450 CDS YP_002272818.1 209397315 6970200 complement(4327910..4328914) 1 NC_011353.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 4328914 trpS 6970200 trpS Escherichia coli O157:H7 str. EC4115 tryptophanyl-tRNA synthetase YP_002272818.1 4327910 R 444450 CDS YP_002272819.1 209397865 6968277 complement(4328907..4329665) 1 NC_011353.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 4329665 gph 6968277 gph Escherichia coli O157:H7 str. EC4115 phosphoglycolate phosphatase YP_002272819.1 4328907 R 444450 CDS YP_002272820.1 209397258 6968857 complement(4329658..4330335) 1 NC_011353.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 4330335 rpe 6968857 rpe Escherichia coli O157:H7 str. EC4115 ribulose-phosphate 3-epimerase YP_002272820.1 4329658 R 444450 CDS YP_002272821.1 209396342 6968216 complement(4330353..4331189) 1 NC_011353.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571; DNA adenine methylase 4331189 dam 6968216 dam Escherichia coli O157:H7 str. EC4115 DNA adenine methylase YP_002272821.1 4330353 R 444450 CDS YP_002272822.1 209399244 6967244 complement(4331296..4332582) 1 NC_011353.1 identified by match to protein family HMM PF05036; hypothetical protein 4332582 damX 6967244 damX Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272822.1 4331296 R 444450 CDS YP_002272823.1 209397467 6970356 complement(4332674..4333762) 1 NC_011353.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 4333762 aroB 6970356 aroB Escherichia coli O157:H7 str. EC4115 3-dehydroquinate synthase YP_002272823.1 4332674 R 444450 CDS YP_002272824.1 209398071 6968438 complement(4333819..4334496) 1 NC_011353.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 4334496 aroK 6968438 aroK Escherichia coli O157:H7 str. EC4115 shikimate kinase I YP_002272824.1 4333819 R 444450 CDS YP_002272825.1 209400800 6969088 complement(4334741..4335979) 1 NC_011353.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 4335979 hofQ 6969088 hofQ Escherichia coli O157:H7 str. EC4115 outer membrane porin HofQ YP_002272825.1 4334741 R 444450 CDS YP_002272826.1 209396224 6972028 complement(4335891..4336295) 1 NC_011353.1 hypothetical protein 4336295 6972028 ECH74115_4696 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272826.1 4335891 R 444450 CDS YP_002272827.1 209399602 6967114 complement(4336285..4336431) 1 NC_011353.1 hypothetical protein 4336431 6967114 ECH74115_4697 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272827.1 4336285 R 444450 CDS YP_002272828.1 209400331 6970743 4336453..4336587 1 NC_011353.1 identified by glimmer; hypothetical protein 4336587 6970743 ECH74115_4698 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272828.1 4336453 D 444450 CDS YP_002272829.1 209399183 6971527 complement(4336709..4337248) 1 NC_011353.1 identified by match to protein family HMM PF05137; PilN family protein 4337248 6971527 ECH74115_4699 Escherichia coli O157:H7 str. EC4115 PilN family protein YP_002272829.1 4336709 R 444450 CDS YP_002272830.1 209398170 6971106 4338146..4340698 1 NC_011353.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 4340698 mrcA 6971106 mrcA Escherichia coli O157:H7 str. EC4115 peptidoglycan synthetase YP_002272830.1 4338146 D 444450 CDS YP_002272831.1 209399440 6969195 complement(4340863..4341423) 1 NC_011353.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 4341423 nudE 6969195 nudE Escherichia coli O157:H7 str. EC4115 ADP-ribose diphosphatase NudE YP_002272831.1 4340863 R 444450 CDS YP_002272832.1 209400230 6970568 4341743..4343878 1 NC_011353.1 identified by match to protein family HMM PF07095; hypothetical protein 4343878 6970568 ECH74115_4703 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272832.1 4341743 D 444450 CDS YP_002272833.1 209400928 6971420 4343943..4344611 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD hydrolase, IA family 4344611 6971420 ECH74115_4704 Escherichia coli O157:H7 str. EC4115 HAD hydrolase, IA family YP_002272833.1 4343943 D 444450 CDS YP_002272834.1 209397739 6972165 4344622..4345023 1 NC_011353.1 identified by match to protein family HMM PF01479; ribosome-associated heat shock protein Hsp15 4345023 hslR 6972165 hslR Escherichia coli O157:H7 str. EC4115 ribosome-associated heat shock protein Hsp15 YP_002272834.1 4344622 D 444450 CDS YP_002272835.1 209396164 6968724 4345042..4345926 1 NC_011353.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 4345926 hslO 6968724 hslO Escherichia coli O157:H7 str. EC4115 Hsp33-like chaperonin YP_002272835.1 4345042 D 444450 CDS YP_002272836.1 209399070 6967047 complement(4345989..4347713) 1 NC_011353.1 hypothetical protein 4347713 6967047 ECH74115_4707 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272836.1 4345989 R 444450 CDS YP_002272837.1 209397286 6970172 complement(4347719..4347847) 1 NC_011353.1 identified by glimmer; hypothetical protein 4347847 6970172 ECH74115_4708 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272837.1 4347719 R 444450 CDS YP_002272838.1 209399361 6968247 4348092..4349714 1 NC_011353.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 4349714 pckA 6968247 pckA Escherichia coli O157:H7 str. EC4115 phosphoenolpyruvate carboxykinase YP_002272838.1 4348092 D 444450 CDS YP_002272839.1 209397426 6970484 complement(4349790..4351142) 1 NC_011353.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 4351142 envZ 6970484 envZ Escherichia coli O157:H7 str. EC4115 osmolarity sensor protein YP_002272839.1 4349790 R 444450 CDS YP_002272840.1 209400499 6968395 complement(4351139..4351858) 1 NC_011353.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 4351858 ompR 6968395 ompR Escherichia coli O157:H7 str. EC4115 osmolarity response regulator YP_002272840.1 4351139 R 444450 CDS YP_002272841.1 209400461 6971704 4352086..4352562 1 NC_011353.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 4352562 greB 6971704 greB Escherichia coli O157:H7 str. EC4115 transcription elongation factor GreB YP_002272841.1 4352086 D 444450 CDS YP_002272842.1 209398543 6971666 4352659..4354980 1 NC_011353.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371; transcriptional accessory protein 4354980 6971666 ECH74115_4713 Escherichia coli O157:H7 str. EC4115 transcriptional accessory protein YP_002272842.1 4352659 D 444450 CDS YP_002272843.1 209399325 6969602 4355045..4355164 1 NC_011353.1 hypothetical protein 4355164 6969602 ECH74115_4714 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272843.1 4355045 D 444450 CDS YP_002272844.1 209397352 6970445 4355418..4355645 1 NC_011353.1 identified by match to protein family HMM PF04023; ferrous iron transport protein A 4355645 feoA 6970445 feoA Escherichia coli O157:H7 str. EC4115 ferrous iron transport protein A YP_002272844.1 4355418 D 444450 CDS YP_002272845.1 209397247 6968319 4355662..4357983 1 NC_011353.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 4357983 feoB 6968319 feoB Escherichia coli O157:H7 str. EC4115 ferrous iron transport protein B YP_002272845.1 4355662 D 444450 CDS YP_002272846.1 209396196 6968205 4357983..4358219 1 NC_011353.1 identified by match to protein family HMM PF09012; hypothetical protein 4358219 6968205 ECH74115_4717 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272846.1 4357983 D 444450 CDS YP_002272847.1 209396746 6967083 4358422..4359300 1 NC_011353.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 4359300 6967083 ECH74115_4718 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272847.1 4358422 D 444450 CDS YP_002272848.1 209398216 6967672 complement(4359327..4360097) 1 NC_011353.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 4360097 6967672 ECH74115_4719 Escherichia coli O157:H7 str. EC4115 carboxylesterase BioH YP_002272848.1 4359327 R 444450 CDS YP_002272849.1 209396165 6969245 4360072..4360818 1 NC_011353.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 4360818 gntX 6969245 gntX Escherichia coli O157:H7 str. EC4115 gluconate periplasmic binding protein YP_002272849.1 4360072 D 444450 CDS YP_002272850.1 209396437 6967049 4360877..4361452 1 NC_011353.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 4361452 gntY 6967049 gntY Escherichia coli O157:H7 str. EC4115 DNA uptake protein YP_002272850.1 4360877 D 444450 CDS YP_002272851.1 209398056 6967347 4361813..4363129 1 NC_011353.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; high-affinity gluconate transporter 4363129 gntT 6967347 gntT Escherichia coli O157:H7 str. EC4115 high-affinity gluconate transporter YP_002272851.1 4361813 D 444450 CDS YP_002272852.1 209397464 6969071 complement(4363174..4365258) 1 NC_011353.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 4365258 malQ 6969071 malQ Escherichia coli O157:H7 str. EC4115 4-alpha-glucanotransferase YP_002272852.1 4363174 R 444450 CDS YP_002272853.1 209397517 6968435 complement(4365268..4367661) 1 NC_011353.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; maltodextrin phosphorylase 4367661 malP 6968435 malP Escherichia coli O157:H7 str. EC4115 maltodextrin phosphorylase YP_002272853.1 4365268 R 444450 CDS YP_002272854.1 209396498 6968490 4368273..4370978 1 NC_011353.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 4370978 malT 6968490 malT Escherichia coli O157:H7 str. EC4115 transcriptional regulator MalT YP_002272854.1 4368273 D 444450 CDS YP_002272855.1 209399939 6967410 4371045..4371323 1 NC_011353.1 identified by match to protein family HMM PF08681; hypothetical protein 4371323 6967410 ECH74115_4726 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272855.1 4371045 D 444450 CDS YP_002272856.1 209399993 6971104 4371314..4371799 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 4371799 6971104 ECH74115_4727 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002272856.1 4371314 D 444450 CDS YP_002272857.1 209399256 6971165 complement(4371849..4372877) 1 NC_011353.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 4372877 rtcA 6971165 rtcA Escherichia coli O157:H7 str. EC4115 RNA 3'-terminal-phosphate cyclase YP_002272857.1 4371849 R 444450 CDS YP_002272858.1 209397766 6970370 complement(4372881..4374107) 1 NC_011353.1 identified by match to protein family HMM PF01139; RtcB protein 4374107 rtcB 6970370 rtcB Escherichia coli O157:H7 str. EC4115 RtcB protein YP_002272858.1 4372881 R 444450 CDS YP_002272859.1 209399613 6968754 4374295..4375893 1 NC_011353.1 identified by match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728; sigma-54 dependent transcriptional regulator RtcR 4375893 rtcR 6968754 rtcR Escherichia coli O157:H7 str. EC4115 sigma-54 dependent transcriptional regulator RtcR YP_002272859.1 4374295 D 444450 CDS YP_002272860.1 209398865 6970757 complement(4375875..4376633) 1 NC_011353.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 4376633 glpR 6970757 glpR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor GlpR YP_002272860.1 4375875 R 444450 CDS YP_002272861.1 209397686 6969951 complement(4376650..4377480) 1 NC_011353.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 4377480 6969951 ECH74115_4732 Escherichia coli O157:H7 str. EC4115 intramembrane serine protease GlpG YP_002272861.1 4376650 R 444450 CDS YP_002272862.1 209397263 6968669 complement(4377525..4377851) 1 NC_011353.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 4377851 glpE 6968669 glpE Escherichia coli O157:H7 str. EC4115 thiosulfate sulfurtransferase YP_002272862.1 4377525 R 444450 CDS YP_002272863.1 209399181 6968221 4378041..4379546 1 NC_011353.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 4379546 glpD 6968221 glpD Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate dehydrogenase YP_002272863.1 4378041 D 444450 CDS YP_002272864.1 209399443 6970289 4379593..4379739 1 NC_011353.1 hypothetical protein 4379739 6970289 ECH74115_4735 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272864.1 4379593 D 444450 CDS YP_002272865.1 209398679 6970571 complement(4379761..4380363) 1 NC_011353.1 hypothetical protein 4380363 6970571 ECH74115_4736 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272865.1 4379761 R 444450 CDS YP_002272866.1 209400933 6969749 complement(4380363..4381355) 1 NC_011353.1 hypothetical protein 4381355 6969749 ECH74115_4737 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272866.1 4380363 R 444450 CDS YP_002272867.1 209400201 6972170 complement(4381381..4382796) 1 NC_011353.1 hypothetical protein 4382796 6972170 ECH74115_4738 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272867.1 4381381 R 444450 CDS YP_002272868.1 209399536 6971389 4382795..4382911 1 NC_011353.1 identified by glimmer; hypothetical protein 4382911 6971389 ECH74115_4739 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272868.1 4382795 D 444450 CDS YP_002272869.1 209398946 6970672 complement(4383014..4385461) 1 NC_011353.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase 4385461 glgP 6970672 glgP Escherichia coli O157:H7 str. EC4115 glycogen phosphorylase YP_002272869.1 4383014 R 444450 CDS YP_002272870.1 209400705 6970040 complement(4385480..4386913) 1 NC_011353.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 4386913 glgA 6970040 glgA Escherichia coli O157:H7 str. EC4115 glycogen synthase YP_002272870.1 4385480 R 444450 CDS YP_002272871.1 209398212 6971928 complement(4386913..4388208) 1 NC_011353.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 4388208 glgC 6971928 glgC Escherichia coli O157:H7 str. EC4115 glucose-1-phosphate adenylyltransferase YP_002272871.1 4386913 R 444450 CDS YP_002272872.1 209397714 6969241 complement(4388226..4390199) 1 NC_011353.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 4390199 glgX 6969241 glgX Escherichia coli O157:H7 str. EC4115 glycogen debranching protein YP_002272872.1 4388226 R 444450 CDS YP_002272873.1 209397102 6968699 complement(4390196..4392382) 1 NC_011353.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 4392382 glgB 6968699 glgB Escherichia coli O157:H7 str. EC4115 glycogen branching protein YP_002272873.1 4390196 R 444450 CDS YP_002272874.1 209395764 6968050 complement(4392655..4393758) 1 NC_011353.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4393758 asd 6968050 asd Escherichia coli O157:H7 str. EC4115 aspartate-semialdehyde dehydrogenase YP_002272874.1 4392655 R 444450 CDS YP_002272875.1 209400660 6966619 4393950..4394543 1 NC_011353.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4394543 6966619 ECH74115_4746 Escherichia coli O157:H7 str. EC4115 dITP- and XTP- hydrolase YP_002272875.1 4393950 D 444450 CDS YP_002272876.1 209399908 6971876 complement(4394589..4395791) 1 NC_011353.1 DNA protecting protein DprA 4395791 6971876 ECH74115_4747 Escherichia coli O157:H7 str. EC4115 DNA protecting protein DprA YP_002272876.1 4394589 R 444450 CDS YP_002272877.1 209397154 6968304 complement(4398055..4399395) 1 NC_011353.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; low affinity gluconate transporter 4399395 gntU 6968304 gntU Escherichia coli O157:H7 str. EC4115 low affinity gluconate transporter YP_002272877.1 4398055 R 444450 CDS YP_002272878.1 209396886 6968106 complement(4399399..4399947) 1 NC_011353.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 4399947 gntK 6968106 gntK Escherichia coli O157:H7 str. EC4115 gluconate kinase YP_002272878.1 4399399 R 444450 CDS YP_002272879.1 209396004 6967823 complement(4400065..4401060) 1 NC_011353.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator GntR 4401060 gntR 6967823 gntR Escherichia coli O157:H7 str. EC4115 transcriptional regulator GntR YP_002272879.1 4400065 R 444450 CDS YP_002272880.1 209400698 6966876 4401138..4401287 1 NC_011353.1 identified by glimmer; hypothetical protein 4401287 6966876 ECH74115_4756 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272880.1 4401138 D 444450 CDS YP_002272881.1 209400398 6971921 complement(4401284..4401979) 1 NC_011353.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883; pirin family protein 4401979 6971921 ECH74115_4755 Escherichia coli O157:H7 str. EC4115 pirin family protein YP_002272881.1 4401284 R 444450 CDS YP_002272882.1 209400110 6971599 complement(4402102..4403139) 1 NC_011353.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; dehydrogenase 4403139 6971599 ECH74115_4757 Escherichia coli O157:H7 str. EC4115 dehydrogenase YP_002272882.1 4402102 R 444450 CDS YP_002272883.1 209399576 6972319 4403473..4403961 1 NC_011353.1 YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 4403961 6972319 ECH74115_4759 Escherichia coli O157:H7 str. EC4115 acetyltransferase YhhY YP_002272883.1 4403473 D 444450 CDS YP_002272884.1 209398979 6970716 4404172..4405083 1 NC_011353.1 hypothetical protein 4405083 6970716 ECH74115_4760 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272884.1 4404172 D 444450 CDS YP_002272885.1 209397919 6970078 complement(4405817..4407562) 1 NC_011353.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 4407562 ggt 6970078 ggt Escherichia coli O157:H7 str. EC4115 gamma-glutamyltranspeptidase YP_002272885.1 4405817 R 444450 CDS YP_002272886.1 209397115 6968918 4407682..4408122 1 NC_011353.1 hypothetical protein 4408122 6968918 ECH74115_4763 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272886.1 4407682 D 444450 CDS YP_002272887.1 209397176 6968064 complement(4408109..4408852) 1 NC_011353.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 4408852 ugpQ 6968064 ugpQ Escherichia coli O157:H7 str. EC4115 glycerophosphodiester phosphodiesterase YP_002272887.1 4408109 R 444450 CDS YP_002272888.1 209399510 6968129 complement(4408849..4409919) 1 NC_011353.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 4409919 ugpC 6968129 ugpC Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate transporter ATP-binding subunit YP_002272888.1 4408849 R 444450 CDS YP_002272889.1 209399034 6970645 complement(4409921..4410766) 1 NC_011353.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 4410766 6970645 ECH74115_4765 Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate transporter membrane protein YP_002272889.1 4409921 R 444450 CDS YP_002272890.1 209398466 6970135 complement(4410763..4411650) 1 NC_011353.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 4411650 ugpA 6970135 ugpA Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate transporter permease YP_002272890.1 4410763 R 444450 CDS YP_002272891.1 209400161 6969519 complement(4411748..4413064) 1 NC_011353.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 4413064 ugpB 6969519 ugpB Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate transporter periplasmic binding protein YP_002272891.1 4411748 R 444450 CDS YP_002272892.1 209399940 6971347 complement(4413275..4413427) 1 NC_011353.1 identified by glimmer; hypothetical protein 4413427 6971347 ECH74115_4768 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272892.1 4413275 R 444450 CDS YP_002272893.1 209396980 6971105 complement(4413424..4414170) 1 NC_011353.1 hypothetical protein 4414170 6971105 ECH74115_4769 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272893.1 4413424 R 444450 CDS YP_002272894.1 209398045 6967921 4414187..4414300 1 NC_011353.1 identified by glimmer; hypothetical protein 4414300 6967921 ECH74115_4771 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272894.1 4414187 D 444450 CDS YP_002272895.1 209396418 6969059 complement(4414289..4415002) 1 NC_011353.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4415002 livF 6969059 livF Escherichia coli O157:H7 str. EC4115 leucine/isoleucine/valine transporter ATP-binding subunit YP_002272895.1 4414289 R 444450 CDS YP_002272896.1 209397425 6967325 complement(4415004..4415771) 1 NC_011353.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4415771 livG 6967325 livG Escherichia coli O157:H7 str. EC4115 leucine/isoleucine/valine transporter ATP-binding subunit YP_002272896.1 4415004 R 444450 CDS YP_002272897.1 209396049 6968394 complement(4415768..4417045) 1 NC_011353.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 4417045 livM 6968394 livM Escherichia coli O157:H7 str. EC4115 leucine/isoleucine/valine transporter permease subunit YP_002272897.1 4415768 R 444450 CDS YP_002272898.1 209400625 6966926 complement(4417042..4417968) 1 NC_011353.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 4417968 livH 6966926 livH Escherichia coli O157:H7 str. EC4115 branched-chain amino acid transporter permease subunit LivH YP_002272898.1 4417042 R 444450 CDS YP_002272899.1 209397677 6971838 complement(4418016..4419125) 1 NC_011353.1 identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK 4419125 livK 6971838 livK Escherichia coli O157:H7 str. EC4115 high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK YP_002272899.1 4418016 R 444450 CDS YP_002272900.1 209396907 6968660 complement(4419277..4419414) 1 NC_011353.1 identified by glimmer; hypothetical protein 4419414 6968660 ECH74115_4776 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272900.1 4419277 R 444450 CDS YP_002272901.1 209398264 6967845 4419549..4419932 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 4419932 6967845 ECH74115_4778 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002272901.1 4419549 D 444450 CDS YP_002272902.1 209399042 6969296 complement(4419929..4420456) 1 NC_011353.1 hypothetical protein 4420456 6969296 ECH74115_4777 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272902.1 4419929 R 444450 CDS YP_002272903.1 209400653 6970144 complement(4420463..4420729) 1 NC_011353.1 identified by match to protein family HMM PF08681; hypothetical protein 4420729 6970144 ECH74115_4779 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272903.1 4420463 R 444450 CDS YP_002272904.1 209399767 6971869 complement(4420879..4421982) 1 NC_011353.1 identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic Leu/Ile/Val-binding protein LivJ 4421982 livJ 6971869 livJ Escherichia coli O157:H7 str. EC4115 high-affinity branched-chain amino acid ABC transporter periplasmic Leu/Ile/Val-binding protein LivJ YP_002272904.1 4420879 R 444450 CDS YP_002272905.1 209398124 6970923 complement(4422253..4423107) 1 NC_011353.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 4423107 rpoH 6970923 rpoH Escherichia coli O157:H7 str. EC4115 RNA polymerase factor sigma-32 YP_002272905.1 4422253 R 444450 CDS YP_002272906.1 209397341 6969144 complement(4423352..4424410) 1 NC_011353.1 ABC transporter membrane protein; cell division protein FtsX 4424410 ftsX 6969144 ftsX Escherichia coli O157:H7 str. EC4115 cell division protein FtsX YP_002272906.1 4423352 R 444450 CDS YP_002272907.1 209399043 6968308 complement(4424403..4425071) 1 NC_011353.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 4425071 ftsE 6968308 ftsE Escherichia coli O157:H7 str. EC4115 cell division protein FtsE YP_002272907.1 4424403 R 444450 CDS YP_002272908.1 209398368 6970145 complement(4425074..4426570) 1 NC_011353.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 4426570 ftsY 6970145 ftsY Escherichia coli O157:H7 str. EC4115 cell division protein FtsY YP_002272908.1 4425074 R 444450 CDS YP_002272909.1 209398100 6969411 4426720..4427316 1 NC_011353.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4427316 rsmD 6969411 rsmD Escherichia coli O157:H7 str. EC4115 16S rRNA m(2)G966-methyltransferase YP_002272909.1 4426720 D 444450 CDS YP_002272910.1 209397555 6969118 4427306..4427575 1 NC_011353.1 identified by match to protein family HMM PF06611; hypothetical protein 4427575 6969118 ECH74115_4786 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272910.1 4427306 D 444450 CDS YP_002272911.1 209396037 6968531 complement(4427578..4427937) 1 NC_011353.1 hypothetical protein 4427937 6968531 ECH74115_4787 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272911.1 4427578 R 444450 CDS YP_002272912.1 209398162 6966913 4428078..4428704 1 NC_011353.1 identified by match to protein family HMM PF07947; hypothetical protein 4428704 6966913 ECH74115_4788 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272912.1 4428078 D 444450 CDS YP_002272913.1 209400548 6969186 4428778..4430976 1 NC_011353.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4430976 zntA 6969186 zntA Escherichia coli O157:H7 str. EC4115 zinc/cadmium/mercury/lead-transporting ATPase YP_002272913.1 4428778 D 444450 CDS YP_002272914.1 209399986 6971757 complement(4431078..4431323) 1 NC_011353.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 4431323 tusA 6971757 tusA Escherichia coli O157:H7 str. EC4115 sulfur transfer protein SirA YP_002272914.1 4431078 R 444450 CDS YP_002272915.1 209398450 6971158 4431544..4432209 1 NC_011353.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 4432209 6971158 ECH74115_4791 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272915.1 4431544 D 444450 CDS YP_002272916.1 209400444 6969503 4432282..4432839 1 NC_011353.1 hypothetical protein 4432839 6969503 ECH74115_4792 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272916.1 4432282 D 444450 CDS YP_002272917.1 209399143 6971648 complement(4432843..4434093) 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator superfamily transporter 4434093 6971648 ECH74115_4793 Escherichia coli O157:H7 str. EC4115 major facilitator superfamily transporter YP_002272917.1 4432843 R 444450 CDS YP_002272918.1 209398386 6970249 4434192..4435241 1 NC_011353.1 identified by match to protein family HMM PF01594; inner membrane protein YhhT 4435241 6970249 ECH74115_4794 Escherichia coli O157:H7 str. EC4115 inner membrane protein YhhT YP_002272918.1 4434192 D 444450 CDS YP_002272919.1 209400414 6969430 4435633..4436010 1 NC_011353.1 hypothetical protein 4436010 6969430 ECH74115_4795 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272919.1 4435633 D 444450 CDS YP_002272920.1 209400004 6971615 4436079..4437137 1 NC_011353.1 identified by match to protein family HMM PF00891; match to protein family HMM PF08242; O-methyltransferase, family 2 4437137 6971615 ECH74115_4796 Escherichia coli O157:H7 str. EC4115 O-methyltransferase, family 2 YP_002272920.1 4436079 D 444450 CDS YP_002272921.1 209395877 6971177 4437178..4437900 1 NC_011353.1 beta-ketoacyl synthase domain-containing protein 4437900 6971177 ECH74115_4797 Escherichia coli O157:H7 str. EC4115 beta-ketoacyl synthase domain-containing protein YP_002272921.1 4437178 D 444450 CDS YP_002272922.1 209397543 6969141 4438693..4438950 1 NC_011353.1 acyl carrier protein 4438950 6969141 ECH74115_4800 Escherichia coli O157:H7 str. EC4115 acyl carrier protein YP_002272922.1 4438693 D 444450 CDS YP_002272923.1 209399103 6968517 4438962..4439213 1 NC_011353.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 4439213 6968517 ECH74115_4801 Escherichia coli O157:H7 str. EC4115 acyl carrier protein YP_002272923.1 4438962 D 444450 CDS YP_002272924.1 209398530 6970205 4439218..4439799 1 NC_011353.1 DNA gyrase subunit B 4439799 6970205 ECH74115_4802 Escherichia coli O157:H7 str. EC4115 DNA gyrase subunit B YP_002272924.1 4439218 D 444450 CDS YP_002272925.1 209400440 6970825 4441144..4441497 1 NC_011353.1 (3R)-hydroxymyristoyl-ACP dehydratase 4441497 6970825 ECH74115_4805 Escherichia coli O157:H7 str. EC4115 (3R)-hydroxymyristoyl-ACP dehydratase YP_002272925.1 4441144 D 444450 CDS YP_002272926.1 209398505 6971643 4441488..4443164 1 NC_011353.1 identified by match to protein family HMM PF00535; family 2 glycosyl transferase 4443164 6971643 ECH74115_4806 Escherichia coli O157:H7 str. EC4115 family 2 glycosyl transferase YP_002272926.1 4441488 D 444450 CDS YP_002272927.1 209400813 6969563 4443168..4443590 1 NC_011353.1 identified by match to protein family HMM PF03061; thioesterase superfamily protein 4443590 6969563 ECH74115_4807 Escherichia coli O157:H7 str. EC4115 thioesterase superfamily protein YP_002272927.1 4443168 D 444450 CDS YP_002272928.1 209400084 6972041 4443587..4444192 1 NC_011353.1 identified by match to protein family HMM PF03548; outer membrane lipoprotein carrier protein LolA 4444192 6972041 ECH74115_4808 Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein carrier protein LolA YP_002272928.1 4443587 D 444450 CDS YP_002272929.1 209396647 6971264 4444161..4446479 1 NC_011353.1 hypothetical protein 4446479 6971264 ECH74115_4809 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272929.1 4444161 D 444450 CDS YP_002272930.1 209396015 6967567 4446476..4447060 1 NC_011353.1 hypothetical protein 4447060 6967567 ECH74115_4810 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272930.1 4446476 D 444450 CDS YP_002272931.1 209395803 6966888 4447062..4448231 1 NC_011353.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 4448231 6966888 ECH74115_4811 Escherichia coli O157:H7 str. EC4115 3-oxoacyl-ACP synthase YP_002272931.1 4447062 D 444450 CDS YP_002272932.1 209397892 6966659 4448228..4448692 1 NC_011353.1 identified by match to protein family HMM PF07977; FabA-like domain-containing protein 4448692 6966659 ECH74115_4812 Escherichia coli O157:H7 str. EC4115 FabA-like domain-containing protein YP_002272932.1 4448228 D 444450 CDS YP_002272933.1 209397871 6968889 4448692..4449423 1 NC_011353.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4449423 fabG 6968889 fabG Escherichia coli O157:H7 str. EC4115 3-ketoacyl-ACP reductase YP_002272933.1 4448692 D 444450 CDS YP_002272934.1 209395848 6968866 4449420..4450649 1 NC_011353.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 4450649 6968866 ECH74115_4814 Escherichia coli O157:H7 str. EC4115 3-oxoacyl-(acyl carrier protein) synthase II YP_002272934.1 4449420 D 444450 CDS YP_002272935.1 209396708 6966706 4450651..4451238 1 NC_011353.1 identified by match to protein family HMM PF01648; holo-(acyl carrier protein) synthase 2 4451238 acpT 6966706 acpT Escherichia coli O157:H7 str. EC4115 holo-(acyl carrier protein) synthase 2 YP_002272935.1 4450651 D 444450 CDS YP_002272936.1 209399938 6967632 4451349..4452923 1 NC_011353.1 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294; nickel ABC transporter periplasmic nickel-binding protein NikA 4452923 nikA 6967632 nikA Escherichia coli O157:H7 str. EC4115 nickel ABC transporter periplasmic nickel-binding protein NikA YP_002272936.1 4451349 D 444450 CDS YP_002272937.1 209400123 6971103 4452923..4453867 1 NC_011353.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4453867 nikB 6971103 nikB Escherichia coli O157:H7 str. EC4115 nickel transporter permease NikB YP_002272937.1 4452923 D 444450 CDS YP_002272938.1 209400711 6971308 4453864..4454697 1 NC_011353.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4454697 nikC 6971308 nikC Escherichia coli O157:H7 str. EC4115 nickel transporter permease NikC YP_002272938.1 4453864 D 444450 CDS YP_002272939.1 209399073 6971934 4454697..4455461 1 NC_011353.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4455461 nikD 6971934 nikD Escherichia coli O157:H7 str. EC4115 nickel transporter ATP-binding protein NikD YP_002272939.1 4454697 D 444450 CDS YP_002272940.1 209399511 6970175 4455458..4456264 1 NC_011353.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4456264 nikE 6970175 nikE Escherichia coli O157:H7 str. EC4115 nickel transporter ATP-binding protein NikE YP_002272940.1 4455458 D 444450 CDS YP_002272941.1 209397817 6970646 4456270..4456671 1 NC_011353.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4456671 nikR 6970646 nikR Escherichia coli O157:H7 str. EC4115 nickel responsive regulator YP_002272941.1 4456270 D 444450 CDS YP_002272942.1 209397083 6968808 4456870..4457616 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4457616 6968808 ECH74115_4822 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002272942.1 4456870 D 444450 CDS YP_002272943.1 209398767 6968029 4457641..4458114 1 NC_011353.1 identified by match to protein family HMM PF00359; PTS system sugar transporter subunit IIA 4458114 6968029 ECH74115_4823 Escherichia coli O157:H7 str. EC4115 PTS system sugar transporter subunit IIA YP_002272943.1 4457641 D 444450 CDS YP_002272944.1 209399527 6969845 4458111..4458392 1 NC_011353.1 identified by match to protein family HMM PF02302; PTS system sugar transporter subunit IIB 4458392 6969845 ECH74115_4824 Escherichia coli O157:H7 str. EC4115 PTS system sugar transporter subunit IIB YP_002272944.1 4458111 D 444450 CDS YP_002272945.1 209397224 6970663 4458469..4459827 1 NC_011353.1 identified by match to protein family HMM PF03611; PTS system sugar transporter subunit IIC 4459827 6970663 ECH74115_4825 Escherichia coli O157:H7 str. EC4115 PTS system sugar transporter subunit IIC YP_002272945.1 4458469 D 444450 CDS YP_002272946.1 209398014 6968182 4459820..4461328 1 NC_011353.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; FGGY family carbohydrate kinase 4461328 6968182 ECH74115_4826 Escherichia coli O157:H7 str. EC4115 FGGY family carbohydrate kinase YP_002272946.1 4459820 D 444450 CDS YP_002272947.1 209396982 6969027 4461318..4461587 1 NC_011353.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; HPr family phosphocarrier protein 4461587 6969027 ECH74115_4827 Escherichia coli O157:H7 str. EC4115 HPr family phosphocarrier protein YP_002272947.1 4461318 D 444450 CDS YP_002272948.1 209396304 6967923 4461619..4462479 1 NC_011353.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 4462479 gatY 6967923 gatY Escherichia coli O157:H7 str. EC4115 fructose-1,6-bisphosphate aldolase YP_002272948.1 4461619 D 444450 CDS YP_002272949.1 209399725 6967199 complement(4462529..4462888) 1 NC_011353.1 identified by match to protein family HMM PF05534; HicB family protein 4462888 6967199 ECH74115_4829 Escherichia coli O157:H7 str. EC4115 HicB family protein YP_002272949.1 4462529 R 444450 CDS YP_002272950.1 209396543 6970878 complement(4463233..4464357) 1 NC_011353.1 identified by match to protein family HMM PF01061; ABC transporter ATP-binding protein 4464357 6970878 ECH74115_4830 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272950.1 4463233 R 444450 CDS YP_002272951.1 209398629 6967457 complement(4464357..4467092) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061; ABC transporter ATP-binding protein 4467092 6967457 ECH74115_4831 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002272951.1 4464357 R 444450 CDS YP_002272952.1 209400736 6969693 complement(4467089..4468156) 1 NC_011353.1 identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family 4468156 6969693 ECH74115_4832 Escherichia coli O157:H7 str. EC4115 auxiliary transport protein, membrane fusion protein (MFP) family YP_002272952.1 4467089 R 444450 CDS YP_002272953.1 209398372 6971961 complement(4468149..4468280) 1 NC_011353.1 hypothetical protein 4468280 6971961 ECH74115_4833 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272953.1 4468149 R 444450 CDS YP_002272954.1 209399213 6969415 complement(4468522..4470144) 1 NC_011353.1 hypothetical protein 4470144 6969415 ECH74115_4834 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272954.1 4468522 R 444450 CDS YP_002272955.1 209399972 6970323 complement(4470406..4472016) 1 NC_011353.1 hypothetical protein 4472016 6970323 ECH74115_4835 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272955.1 4470406 R 444450 CDS YP_002272956.1 209400722 6971143 4472400..4473452 1 NC_011353.1 hypothetical protein 4473452 6971143 ECH74115_4836 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272956.1 4472400 D 444450 CDS YP_002272957.1 209396835 6967009 complement(4473770..4474972) 1 NC_011353.1 identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; pyridine nucleotide-disulfide oxidoreductase family protein 4474972 6967009 ECH74115_4838 Escherichia coli O157:H7 str. EC4115 pyridine nucleotide-disulfide oxidoreductase family protein YP_002272957.1 4473770 R 444450 CDS YP_002272958.1 209397927 6967768 4475204..4476703 1 NC_011353.1 identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 1 4476703 pitA 6967768 pitA Escherichia coli O157:H7 str. EC4115 low-affinity inorganic phosphate transporter 1 YP_002272958.1 4475204 D 444450 CDS YP_002272959.1 209398495 6968927 complement(4476774..4477055) 1 NC_011353.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 4477055 uspB 6968927 uspB Escherichia coli O157:H7 str. EC4115 universal stress protein UspB YP_002272959.1 4476774 R 444450 CDS YP_002272960.1 209398493 6969552 4477500..4477934 1 NC_011353.1 identified by match to protein family HMM PF00582; universal stress protein A 4477934 uspA 6969552 uspA Escherichia coli O157:H7 str. EC4115 universal stress protein A YP_002272960.1 4477500 D 444450 CDS YP_002272961.1 209397930 6969550 complement(4478117..4478296) 1 NC_011353.1 hypothetical protein 4478296 6969550 ECH74115_4842 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272961.1 4478117 R 444450 CDS YP_002272962.1 209397711 6968930 4478251..4479720 1 NC_011353.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4479720 6968930 ECH74115_4843 Escherichia coli O157:H7 str. EC4115 inner membrane transporter YhiP YP_002272962.1 4478251 D 444450 CDS YP_002272963.1 209397122 6968695 complement(4479769..4480521) 1 NC_011353.1 predicted SAM-dependent methyltransferase; methyltransferase 4480521 6968695 ECH74115_4844 Escherichia coli O157:H7 str. EC4115 methyltransferase YP_002272963.1 4479769 R 444450 CDS YP_002272964.1 209396642 6968071 complement(4480529..4482571) 1 NC_011353.1 identified by match to protein family HMM PF01432; oligopeptidase A 4482571 prlC 6968071 prlC Escherichia coli O157:H7 str. EC4115 oligopeptidase A YP_002272964.1 4480529 R 444450 CDS YP_002272965.1 209396007 6967562 4482774..4483616 1 NC_011353.1 identified by match to protein family HMM PF04378; DNA utilization protein YhiR 4483616 yhiR 6967562 yhiR Escherichia coli O157:H7 str. EC4115 DNA utilization protein YhiR YP_002272965.1 4482774 D 444450 CDS YP_002272966.1 209397055 6966879 4483688..4485040 1 NC_011353.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4485040 gor 6966879 gor Escherichia coli O157:H7 str. EC4115 glutathione reductase YP_002272966.1 4483688 D 444450 CDS YP_002272967.1 209396971 6968001 complement(4485094..4485210) 1 NC_011353.1 identified by glimmer; hypothetical protein 4485210 6968001 ECH74115_4848 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272967.1 4485094 R 444450 CDS YP_002272968.1 209395964 6967911 4485205..4485378 1 NC_011353.1 identified by glimmer; hypothetical protein 4485378 6967911 ECH74115_4849 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272968.1 4485205 D 444450 CDS YP_002272969.1 209400520 6966831 4485921..4486274 1 NC_011353.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 4486274 arsR 6966831 arsR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor ArsR YP_002272969.1 4485921 D 444450 CDS YP_002272970.1 209400831 6971727 4486328..4487617 1 NC_011353.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935; arsenical pump membrane protein 4487617 arsB 6971727 arsB Escherichia coli O157:H7 str. EC4115 arsenical pump membrane protein YP_002272970.1 4486328 D 444450 CDS YP_002272971.1 209400025 6972059 4487630..4488055 1 NC_011353.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 4488055 arsC2 6972059 arsC2 Escherichia coli O157:H7 str. EC4115 arsenate reductase YP_002272971.1 4487630 D 444450 CDS YP_002272972.1 209400492 6970821 4490151..4490717 1 NC_011353.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752; outer membrane lipoprotein, Slp family 4490717 6970821 ECH74115_4854 Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein, Slp family YP_002272972.1 4490151 D 444450 CDS YP_002272973.1 209396199 6971697 4490873..4491403 1 NC_011353.1 identified by match to protein family HMM PF00196; transcriptional regulator DctR 4491403 dctR 6971697 dctR Escherichia coli O157:H7 str. EC4115 transcriptional regulator DctR YP_002272973.1 4490873 D 444450 CDS YP_002272974.1 209396915 6967086 complement(4491464..4492492) 1 NC_011353.1 identified by match to protein family HMM PF05171; hemin transport protein HmuS 4492492 hmuS 6967086 hmuS Escherichia coli O157:H7 str. EC4115 hemin transport protein HmuS YP_002272974.1 4491464 R 444450 CDS YP_002272975.1 209396568 6967853 complement(4492541..4494523) 1 NC_011353.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01785; match to protein family HMM TIGR01786; outer membrane heme/hemoglobin receptor ChuA 4494523 chuA 6967853 chuA Escherichia coli O157:H7 str. EC4115 outer membrane heme/hemoglobin receptor ChuA YP_002272975.1 4492541 R 444450 CDS YP_002272976.1 209397132 6967482 4494462..4494605 1 NC_011353.1 hypothetical protein 4494605 6967482 ECH74115_4858 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272976.1 4494462 D 444450 CDS YP_002272977.1 209398660 6969808 complement(4494799..4495005) 1 NC_011353.1 hypothetical protein 4495005 6969808 ECH74115_4860 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272977.1 4494799 R 444450 CDS YP_002272978.1 209396547 6969730 4495266..4496120 1 NC_011353.1 identified by match to protein family HMM PF01497; periplasmic-binding protein 4496120 6969730 ECH74115_4861 Escherichia coli O157:H7 str. EC4115 periplasmic-binding protein YP_002272978.1 4495266 D 444450 CDS YP_002272979.1 209395960 6967461 4496140..4497477 1 NC_011353.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4497477 6967461 ECH74115_4862 Escherichia coli O157:H7 str. EC4115 coproporphyrinogen III oxidase YP_002272979.1 4496140 D 444450 CDS YP_002272980.1 209397453 6966827 4497490..4497984 1 NC_011353.1 identified by match to protein family HMM PF06228; hypothetical protein 4497984 6966827 ECH74115_4863 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272980.1 4497490 D 444450 CDS YP_002272981.1 209396759 6968424 4497984..4498607 1 NC_011353.1 hypothetical protein 4498607 6968424 ECH74115_4864 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272981.1 4497984 D 444450 CDS YP_002272982.1 209396092 6967686 4498692..4499648 1 NC_011353.1 identified by match to protein family HMM PF01032; ABC transporter iron chelate uptake transporter (FeCT) family, permease 4499648 6967686 ECH74115_4865 Escherichia coli O157:H7 str. EC4115 ABC transporter iron chelate uptake transporter (FeCT) family, permease YP_002272982.1 4498692 D 444450 CDS YP_002272983.1 209400972 6966971 4499645..4500415 1 NC_011353.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4500415 hmuV 6966971 hmuV Escherichia coli O157:H7 str. EC4115 hemin importer ATP-binding subunit YP_002272983.1 4499645 D 444450 CDS YP_002272984.1 209398123 6972212 complement(4500467..4501126) 1 NC_011353.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 4501126 6972212 ECH74115_4867 Escherichia coli O157:H7 str. EC4115 Mg(2+) transport ATPase YP_002272984.1 4500467 R 444450 CDS YP_002272985.1 209397371 6969143 complement(4501178..4501516) 1 NC_011353.1 acid-resistance protein 4501516 hdeB 6969143 hdeB Escherichia coli O157:H7 str. EC4115 acid-resistance protein YP_002272985.1 4501178 R 444450 CDS YP_002272986.1 209396938 6968337 complement(4501620..4501952) 1 NC_011353.1 inactive form; acid-resistance protein 4501952 6968337 ECH74115_4869 Escherichia coli O157:H7 str. EC4115 acid-resistance protein YP_002272986.1 4501620 R 444450 CDS YP_002272987.1 209396491 6967876 4502207..4502779 1 NC_011353.1 acid-resistance membrane protein 4502779 6967876 ECH74115_4870 Escherichia coli O157:H7 str. EC4115 acid-resistance membrane protein YP_002272987.1 4502207 D 444450 CDS YP_002272988.1 209400509 6967403 4503578..4504105 1 NC_011353.1 transcriptional regulator GadE 4504105 gadE 6967403 gadE Escherichia coli O157:H7 str. EC4115 transcriptional regulator GadE YP_002272988.1 4503578 D 444450 CDS YP_002272989.1 209399998 6971714 complement(4504422..4504514) 1 NC_011353.1 identified by glimmer; hypothetical protein 4504514 6971714 ECH74115_4872 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272989.1 4504422 R 444450 CDS YP_002272990.1 209398509 6971171 4504444..4505601 1 NC_011353.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4505601 mdtE 6971171 mdtE Escherichia coli O157:H7 str. EC4115 multidrug efflux system protein MdtE YP_002272990.1 4504444 D 444450 CDS YP_002272991.1 209399072 6969567 4505626..4508739 1 NC_011353.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; multidrug resistance protein MdtF 4508739 mdtF 6969567 mdtF Escherichia coli O157:H7 str. EC4115 multidrug resistance protein MdtF YP_002272991.1 4505626 D 444450 CDS YP_002272992.1 209397355 6970174 complement(4509102..4509830) 1 NC_011353.1 identified by match to protein family HMM PF00165; transcriptional regulator GadW 4509830 gadW 6970174 gadW Escherichia coli O157:H7 str. EC4115 transcriptional regulator GadW YP_002272992.1 4509102 R 444450 CDS YP_002272993.1 209398111 6972303 complement(4510198..4511022) 1 NC_011353.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 4511022 gadX 6972303 gadX Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator GadX YP_002272993.1 4510198 R 444450 CDS YP_002272994.1 209396216 6969130 complement(4511107..4511277) 1 NC_011353.1 identified by glimmer; hypothetical protein 4511277 6969130 ECH74115_4878 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272994.1 4511107 R 444450 CDS YP_002272995.1 209396955 6967105 complement(4511393..4512793) 1 NC_011353.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase GadB 4512793 gadB 6967105 gadB Escherichia coli O157:H7 str. EC4115 glutamate decarboxylase GadB YP_002272995.1 4511393 R 444450 CDS YP_002272996.1 209397635 6967893 complement(4513004..4514401) 1 NC_011353.1 identified by match to protein family HMM PF03150; di-heme cytochrome c peroxidase family protein 4514401 6967893 ECH74115_4880 Escherichia coli O157:H7 str. EC4115 di-heme cytochrome c peroxidase family protein YP_002272996.1 4513004 R 444450 CDS YP_002272997.1 209398218 6968617 4514582..4514701 1 NC_011353.1 identified by glimmer; hypothetical protein 4514701 6968617 ECH74115_4881 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002272997.1 4514582 D 444450 CDS YP_002272998.1 209396219 6969247 4514806..4516455 1 NC_011353.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4516455 treF 6969247 treF Escherichia coli O157:H7 str. EC4115 trehalase YP_002272998.1 4514806 D 444450 CDS YP_002272999.1 209396704 6967109 complement(4516506..4517108) 1 NC_011353.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281; LuxR family transcriptional regulator 4517108 6967109 ECH74115_4883 Escherichia coli O157:H7 str. EC4115 LuxR family transcriptional regulator YP_002272999.1 4516506 R 444450 CDS YP_002273000.1 209396325 6967628 4517556..4518527 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4518527 6967628 ECH74115_4884 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002273000.1 4517556 D 444450 CDS YP_002273001.1 209396850 6967222 4518576..4519589 1 NC_011353.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766; ribonuclease 4519589 6967222 ECH74115_4885 Escherichia coli O157:H7 str. EC4115 ribonuclease YP_002273001.1 4518576 D 444450 CDS YP_002273002.1 209400488 6967783 4520001..4521323 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; MFS transporter metabolite:H+ symporter (MHS) family protein 4521323 6967783 ECH74115_4886 Escherichia coli O157:H7 str. EC4115 MFS transporter metabolite:H+ symporter (MHS) family protein YP_002273002.1 4520001 D 444450 CDS YP_002273003.1 209398465 6971693 complement(4521505..4523565) 1 NC_011353.1 identified by match to protein family HMM PF05170; AsmA family protein 4523565 6971693 ECH74115_4887 Escherichia coli O157:H7 str. EC4115 AsmA family protein YP_002273003.1 4521505 R 444450 CDS YP_002273004.1 209396046 6969518 complement(4523635..4524270) 1 NC_011353.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 4524270 6969518 ECH74115_4888 Escherichia coli O157:H7 str. EC4115 EAL domain-containing protein YP_002273004.1 4523635 R 444450 CDS YP_002273005.1 209398108 6966922 complement(4524402..4524629) 1 NC_011353.1 identified by glimmer; hypothetical protein 4524629 6966922 ECH74115_4889 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273005.1 4524402 R 444450 CDS YP_002273006.1 209400541 6969127 4524634..4525563 1 NC_011353.1 identified by match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase 4525563 kdgK 6969127 kdgK Escherichia coli O157:H7 str. EC4115 2-dehydro-3-deoxygluconokinase YP_002273006.1 4524634 D 444450 CDS YP_002273007.1 209399996 6971749 complement(4525659..4527155) 1 NC_011353.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 (pitrilysin) family 4527155 6971749 ECH74115_4891 Escherichia coli O157:H7 str. EC4115 peptidase, M16 (pitrilysin) family YP_002273007.1 4525659 R 444450 CDS YP_002273008.1 209398499 6971169 complement(4527376..4528662) 1 NC_011353.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4528662 dctA 6971169 dctA Escherichia coli O157:H7 str. EC4115 C4-dicarboxylate transporter DctA YP_002273008.1 4527376 R 444450 CDS YP_002273009.1 209400592 6969557 4528666..4528764 1 NC_011353.1 identified by glimmer; hypothetical protein 4528764 6969557 ECH74115_4893 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273009.1 4528666 D 444450 CDS YP_002273010.1 209400445 6971803 complement(4528845..4530833) 1 NC_011353.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase 4530833 6971803 ECH74115_4894 Escherichia coli O157:H7 str. EC4115 phosphodiesterase YP_002273010.1 4528845 R 444450 CDS YP_002273011.1 209396215 6971649 complement(4530915..4534388) 1 NC_011353.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 4534388 6971649 ECH74115_4895 Escherichia coli O157:H7 str. EC4115 cellulose synthase subunit BcsC YP_002273011.1 4530915 R 444450 CDS YP_002273012.1 209396242 6967104 complement(4534370..4535482) 1 NC_011353.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 4535482 bcsZ 6967104 bcsZ Escherichia coli O157:H7 str. EC4115 endo-1,4-D-glucanase YP_002273012.1 4534370 R 444450 CDS YP_002273013.1 209396985 6967134 complement(4535483..4537858) 1 NC_011353.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 4537858 bcsB 6967134 bcsB Escherichia coli O157:H7 str. EC4115 cellulose synthase regulator protein YP_002273013.1 4535483 R 444450 CDS YP_002273014.1 209397409 6967926 complement(4537869..4540487) 1 NC_011353.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 4540487 bcsA 6967926 bcsA Escherichia coli O157:H7 str. EC4115 cellulose synthase catalytic subunit YP_002273014.1 4537869 R 444450 CDS YP_002273015.1 209396749 6967058 complement(4541248..4541436) 1 NC_011353.1 hypothetical protein 4541436 6967058 ECH74115_4901 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273015.1 4541248 R 444450 CDS YP_002273016.1 209397670 6967675 4541721..4543280 1 NC_011353.1 identified by match to protein family HMM TIGR03369; hypothetical protein 4543280 6967675 ECH74115_4902 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273016.1 4541721 D 444450 CDS YP_002273017.1 209398195 6968653 4543277..4543468 1 NC_011353.1 identified by match to protein family HMM TIGR03493; cellulose biosynthesis protein BcsF 4543468 bcsF 6968653 bcsF Escherichia coli O157:H7 str. EC4115 cellulose biosynthesis protein BcsF YP_002273017.1 4543277 D 444450 CDS YP_002273018.1 209398532 6969223 4543465..4545144 1 NC_011353.1 identified by match to protein family HMM TIGR03368; hypothetical protein 4545144 6969223 ECH74115_4904 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273018.1 4543465 D 444450 CDS YP_002273019.1 209397776 6969591 complement(4545231..4545398) 1 NC_011353.1 hypothetical protein 4545398 6969591 ECH74115_4905 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273019.1 4545231 R 444450 CDS YP_002273020.1 209396996 6968764 complement(4545503..4545664) 1 NC_011353.1 identified by glimmer; hypothetical protein 4545664 6968764 ECH74115_4906 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273020.1 4545503 R 444450 CDS YP_002273021.1 209397623 6967938 4545814..4547085 1 NC_011353.1 identified by match to protein family HMM TIGR00814; serine transporter family protein 4547085 6967938 ECH74115_4907 Escherichia coli O157:H7 str. EC4115 serine transporter family protein YP_002273021.1 4545814 D 444450 CDS YP_002273022.1 209399147 6968605 complement(4547115..4548119) 1 NC_011353.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4548119 dppF 6968605 dppF Escherichia coli O157:H7 str. EC4115 dipeptide transporter ATP-binding subunit YP_002273022.1 4547115 R 444450 CDS YP_002273023.1 209398420 6970254 complement(4548116..4549099) 1 NC_011353.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4549099 dppD 6970254 dppD Escherichia coli O157:H7 str. EC4115 dipeptide transporter ATP-binding subunit YP_002273023.1 4548116 R 444450 CDS YP_002273024.1 209399011 6969468 complement(4549110..4550012) 1 NC_011353.1 identified by match to protein family HMM PF00528; dipeptide transporter 4550012 dppC 6969468 dppC Escherichia coli O157:H7 str. EC4115 dipeptide transporter YP_002273024.1 4549110 R 444450 CDS YP_002273025.1 209398114 6970111 complement(4550022..4551167) 1 NC_011353.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4551167 dppB 6970111 dppB Escherichia coli O157:H7 str. EC4115 dipeptide transporter permease DppB YP_002273025.1 4550022 R 444450 CDS YP_002273026.1 209396913 6969133 4551059..4551202 1 NC_011353.1 identified by glimmer; hypothetical protein 4551202 6969133 ECH74115_4913 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273026.1 4551059 D 444450 CDS YP_002273027.1 209396782 6967851 complement(4551192..4552799) 1 NC_011353.1 identified by match to protein family HMM PF00496; dipeptide ABC transporter substrate-binding protein 4552799 dppA 6967851 dppA Escherichia coli O157:H7 str. EC4115 dipeptide ABC transporter substrate-binding protein YP_002273027.1 4551192 R 444450 CDS YP_002273028.1 209399321 6972391 complement(4553712..4555403) 1 NC_011353.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4555403 6972391 ECH74115_4916 Escherichia coli O157:H7 str. EC4115 phosphoethanolamine transferase YP_002273028.1 4553712 R 444450 CDS YP_002273029.1 209398023 6970440 complement(4555658..4556188) 1 NC_011353.1 identified by match to protein family HMM PF00419; protein LpfE 4556188 6970440 ECH74115_4917 Escherichia coli O157:H7 str. EC4115 protein LpfE YP_002273029.1 4555658 R 444450 CDS YP_002273030.1 209397444 6969036 complement(4556193..4557248) 1 NC_011353.1 identified by match to protein family HMM PF00419; protein LpfD 4557248 6969036 ECH74115_4918 Escherichia coli O157:H7 str. EC4115 protein LpfD YP_002273030.1 4556193 R 444450 CDS YP_002273031.1 209398252 6967233 complement(4559865..4560554) 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC 4560554 6967233 ECH74115_4921 Escherichia coli O157:H7 str. EC4115 chaperone protein FimC YP_002273031.1 4559865 R 444450 CDS YP_002273032.1 209397169 6969284 complement(4560616..4561140) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 4561140 6969284 ECH74115_4922 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002273032.1 4560616 R 444450 CDS YP_002273033.1 209396715 6968122 complement(4561484..4562686) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890; inner membrane protein YhjX 4562686 6968122 ECH74115_4923 Escherichia coli O157:H7 str. EC4115 inner membrane protein YhjX YP_002273033.1 4561484 R 444450 CDS YP_002273034.1 209396161 6967640 complement(4562915..4563613) 1 NC_011353.1 hypothetical protein 4563613 6967640 ECH74115_4924 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273034.1 4562915 R 444450 CDS YP_002273035.1 209395727 6967044 4563771..4564334 1 NC_011353.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 4564334 tag 6967044 tag Escherichia coli O157:H7 str. EC4115 3-methyladenine DNA glycosylase YP_002273035.1 4563771 D 444450 CDS YP_002273036.1 209400176 6966582 4564331..4564771 1 NC_011353.1 identified by match to protein family HMM PF00583; hypothetical protein 4564771 6966582 ECH74115_4927 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273036.1 4564331 D 444450 CDS YP_002273037.1 209396486 6971363 complement(4564740..4567073) 1 NC_011353.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; biotin sulfoxide reductase 4567073 bisC 6971363 bisC Escherichia coli O157:H7 str. EC4115 biotin sulfoxide reductase YP_002273037.1 4564740 R 444450 CDS YP_002273038.1 209400986 6967398 4567226..4567885 1 NC_011353.1 identified by match to protein family HMM PF00691; match to protein family HMM PF05433; outer membrane lipoprotein 4567885 6967398 ECH74115_4928 Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein YP_002273038.1 4567226 D 444450 CDS YP_002273039.1 209395767 6972228 4567989..4568963 1 NC_011353.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; 2-ketogluconate reductase 4568963 tkrA 6972228 tkrA Escherichia coli O157:H7 str. EC4115 2-ketogluconate reductase YP_002273039.1 4567989 D 444450 CDS YP_002273040.1 209396479 6966623 complement(4569013..4569723) 1 NC_011353.1 lipoprotein 4569723 6966623 ECH74115_4930 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002273040.1 4569013 R 444450 CDS YP_002273041.1 209400094 6967390 4570157..4570447 1 NC_011353.1 transcriptional regulator 4570447 6967390 ECH74115_4931 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002273041.1 4570157 D 444450 CDS YP_002273042.1 209400365 6971276 4570728..4570940 1 NC_011353.1 identified by match to protein family HMM PF00313; major cold shock protein 4570940 6971276 ECH74115_4932 Escherichia coli O157:H7 str. EC4115 major cold shock protein YP_002273042.1 4570728 D 444450 CDS YP_002273043.1 209399335 6971563 complement(4571128..4571280) 1 NC_011353.1 identified by match to protein family HMM PF01848; small toxic polypeptide 4571280 hokA 6971563 hokA Escherichia coli O157:H7 str. EC4115 small toxic polypeptide YP_002273043.1 4571128 R 444450 CDS YP_002273044.1 209399717 6970455 complement(4571603..4573672) 1 NC_011353.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4573672 glyS 6970455 glyS Escherichia coli O157:H7 str. EC4115 glycyl-tRNA synthetase subunit beta YP_002273044.1 4571603 R 444450 CDS YP_002273045.1 209396370 6970869 complement(4573682..4574593) 1 NC_011353.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4574593 glyQ 6970869 glyQ Escherichia coli O157:H7 str. EC4115 glycyl-tRNA synthetase subunit alpha YP_002273045.1 4573682 R 444450 CDS YP_002273046.1 209395792 6967274 complement(4574688..4574987) 1 NC_011353.1 hypothetical protein 4574987 6967274 ECH74115_4936 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273046.1 4574688 R 444450 CDS YP_002273047.1 209400863 6966648 4575162..4576157 1 NC_011353.1 acyltransferase family protein 4576157 6966648 ECH74115_4937 Escherichia coli O157:H7 str. EC4115 acyltransferase family protein YP_002273047.1 4575162 D 444450 CDS YP_002273048.1 209400282 6972094 complement(4576199..4576636) 1 NC_011353.1 identified by match to protein family HMM PF05360; hypothetical protein 4576636 6972094 ECH74115_4938 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273048.1 4576199 R 444450 CDS YP_002273049.1 209399370 6971476 complement(4576682..4577023) 1 NC_011353.1 identified by match to protein family HMM PF05360; hypothetical protein 4577023 6971476 ECH74115_4939 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273049.1 4576682 R 444450 CDS YP_002273050.1 209398801 6970495 complement(4577192..4578646) 1 NC_011353.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase 4578646 xylB 6970495 xylB Escherichia coli O157:H7 str. EC4115 xylulokinase YP_002273050.1 4577192 R 444450 CDS YP_002273051.1 209400679 6969880 complement(4578718..4580040) 1 NC_011353.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4580040 xylA 6969880 xylA Escherichia coli O157:H7 str. EC4115 xylose isomerase YP_002273051.1 4578718 R 444450 CDS YP_002273052.1 209400101 6971899 4580406..4581398 1 NC_011353.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4581398 xylF 6971899 xylF Escherichia coli O157:H7 str. EC4115 D-xylose transporter subunit XylF YP_002273052.1 4580406 D 444450 CDS YP_002273053.1 209399539 6971283 4581476..4583017 1 NC_011353.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4583017 xylG 6971283 xylG Escherichia coli O157:H7 str. EC4115 xylose transporter ATP-binding subunit YP_002273053.1 4581476 D 444450 CDS YP_002273054.1 209398987 6970675 4582995..4584176 1 NC_011353.1 identified by match to protein family HMM PF02653; D-xylose ABC transporter permease 4584176 xylH 6970675 xylH Escherichia coli O157:H7 str. EC4115 D-xylose ABC transporter permease YP_002273054.1 4582995 D 444450 CDS YP_002273055.1 209398178 6970086 4584254..4585432 1 NC_011353.1 identified by match to protein family HMM PF00165; xylose operon regulatory protein 4585432 xylR 6970086 xylR Escherichia coli O157:H7 str. EC4115 xylose operon regulatory protein YP_002273055.1 4584254 D 444450 CDS YP_002273056.1 209397567 6969204 complement(4585540..4586364) 1 NC_011353.1 identified by match to protein family HMM PF01832; hypothetical protein 4586364 bax 6969204 bax Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273056.1 4585540 R 444450 CDS YP_002273057.1 209399658 6968543 4586684..4588714 1 NC_011353.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4588714 malS 6968543 malS Escherichia coli O157:H7 str. EC4115 periplasmic alpha-amylase YP_002273057.1 4586684 D 444450 CDS YP_002273058.1 209398430 6970805 4588892..4590145 1 NC_011353.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4590145 avtA 6970805 avtA Escherichia coli O157:H7 str. EC4115 valine--pyruvate transaminase YP_002273058.1 4588892 D 444450 CDS YP_002273059.1 209397848 6969478 complement(4590297..4590770) 1 NC_011353.1 identified by match to protein family HMM PF00037; 4Fe-4S binding protein 4590770 6969478 ECH74115_4949 Escherichia coli O157:H7 str. EC4115 4Fe-4S binding protein YP_002273059.1 4590297 R 444450 CDS YP_002273060.1 209397268 6968840 complement(4591014..4591829) 1 NC_011353.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; AraC family transcriptional regulator 4591829 6968840 ECH74115_4950 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002273060.1 4591014 R 444450 CDS YP_002273061.1 209400085 6968228 4592055..4593455 1 NC_011353.1 identified by match to protein family HMM TIGR00792; sugar transporter glycoside-pentoside-hexuronide family 4593455 6968228 ECH74115_4951 Escherichia coli O157:H7 str. EC4115 sugar transporter glycoside-pentoside-hexuronide family YP_002273061.1 4592055 D 444450 CDS YP_002273062.1 209399472 6971265 4593466..4595436 1 NC_011353.1 identified by match to protein family HMM PF07944; hypothetical protein 4595436 6971265 ECH74115_4952 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273062.1 4593466 D 444450 CDS YP_002273063.1 209396238 6970604 complement(4595566..4596306) 1 NC_011353.1 identified by match to protein family HMM PF06629; MltA-interacting protein MipA 4596306 6970604 ECH74115_4953 Escherichia coli O157:H7 str. EC4115 MltA-interacting protein MipA YP_002273063.1 4595566 R 444450 CDS YP_002273064.1 209398817 6967129 4596430..4597404 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4597404 6967129 ECH74115_4955 Escherichia coli O157:H7 str. EC4115 LysR family transcriptional regulator YP_002273064.1 4596430 D 444450 CDS YP_002273065.1 209400974 6969898 complement(4597401..4598537) 1 NC_011353.1 identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family 4598537 6969898 ECH74115_4954 Escherichia coli O157:H7 str. EC4115 auxiliary transport protein, membrane fusion protein (MFP) family YP_002273065.1 4597401 R 444450 CDS YP_002273066.1 209399421 6972214 complement(4598543..4598866) 1 NC_011353.1 hypothetical protein 4598866 6972214 ECH74115_4956 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273066.1 4598543 R 444450 CDS YP_002273067.1 209397913 6968293 complement(4599411..4600949) 1 NC_011353.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase B 4600949 aldB 6968293 aldB Escherichia coli O157:H7 str. EC4115 aldehyde dehydrogenase B YP_002273067.1 4599411 R 444450 CDS YP_002273068.1 209395834 6968912 complement(4601057..4602352) 1 NC_011353.1 identified by match to protein family HMM PF02661; Fic family protein 4602352 6968912 ECH74115_4959 Escherichia coli O157:H7 str. EC4115 Fic family protein YP_002273068.1 4601057 R 444450 CDS YP_002273069.1 209400248 6966691 complement(4602482..4603633) 1 NC_011353.1 identified by match to protein family HMM PF00465; alcohol dehydrogenase 4603633 adhB 6966691 adhB Escherichia coli O157:H7 str. EC4115 alcohol dehydrogenase YP_002273069.1 4602482 R 444450 CDS YP_002273070.1 209399470 6971439 complement(4603822..4605666) 1 NC_011353.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475; selenocysteinyl-tRNA-specific translation factor 4605666 selB 6971439 selB Escherichia coli O157:H7 str. EC4115 selenocysteinyl-tRNA-specific translation factor YP_002273070.1 4603822 R 444450 CDS YP_002273071.1 209397198 6970602 complement(4605663..4607054) 1 NC_011353.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4607054 selA 6970602 selA Escherichia coli O157:H7 str. EC4115 selenocysteine synthase YP_002273071.1 4605663 R 444450 CDS YP_002273072.1 209397735 6968154 complement(4607152..4607760) 1 NC_011353.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 4607760 6968154 ECH74115_4963 Escherichia coli O157:H7 str. EC4115 glutathione S-transferase YP_002273072.1 4607152 R 444450 CDS YP_002273073.1 209395814 6968720 4607759..4607902 1 NC_011353.1 identified by glimmer; hypothetical protein 4607902 6968720 ECH74115_4964 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273073.1 4607759 D 444450 CDS YP_002273074.1 209396291 6966670 4607989..4612218 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; Rhs family protein 4612218 6966670 ECH74115_4965 Escherichia coli O157:H7 str. EC4115 Rhs family protein YP_002273074.1 4607989 D 444450 CDS YP_002273075.1 209400677 6967186 4613566..4613835 1 NC_011353.1 hypothetical protein 4613835 6967186 ECH74115_4966 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273075.1 4613566 D 444450 CDS YP_002273076.1 209399731 6971896 complement(4614294..4615430) 1 NC_011353.1 identified by match to protein family HMM PF00529; auxiliary transport protein, membrane fusion protein (MFP) family 4615430 6971896 ECH74115_4967 Escherichia coli O157:H7 str. EC4115 auxiliary transport protein, membrane fusion protein (MFP) family YP_002273076.1 4614294 R 444450 CDS YP_002273077.1 209399646 6970884 complement(4615433..4615795) 1 NC_011353.1 hypothetical protein 4615795 6970884 ECH74115_4968 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273077.1 4615433 R 444450 CDS YP_002273078.1 209396799 6970791 4616332..4618245 1 NC_011353.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit IIABC 4618245 mtlA 6970791 mtlA Escherichia coli O157:H7 str. EC4115 PTS system mannitol-specific transporter subunit IIABC YP_002273078.1 4616332 D 444450 CDS YP_002273079.1 209395785 6967731 4618340..4619488 1 NC_011353.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol-1-phosphate 5-dehydrogenase 4619488 mtlD 6967731 mtlD Escherichia coli O157:H7 str. EC4115 mannitol-1-phosphate 5-dehydrogenase YP_002273079.1 4618340 D 444450 CDS YP_002273080.1 209400358 6966641 4619488..4620075 1 NC_011353.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4620075 mtlR 6966641 mtlR Escherichia coli O157:H7 str. EC4115 mannitol repressor protein YP_002273080.1 4619488 D 444450 CDS YP_002273081.1 209399974 6971556 complement(4620087..4620296) 1 NC_011353.1 hypothetical protein 4620296 6971556 ECH74115_4972 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273081.1 4620087 R 444450 CDS YP_002273082.1 209399195 6971146 4620581..4620943 1 NC_011353.1 hypothetical protein 4620943 6971146 ECH74115_4973 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273082.1 4620581 D 444450 CDS YP_002273083.1 209399754 6970303 4621588..4622169 1 NC_011353.1 lipoprotein 4622169 6970303 ECH74115_4974 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002273083.1 4621588 D 444450 CDS YP_002273084.1 209397689 6970910 4622213..4626979 1 NC_011353.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; Hep_Hag family protein 4626979 6970910 ECH74115_4975 Escherichia coli O157:H7 str. EC4115 Hep_Hag family protein YP_002273084.1 4622213 D 444450 CDS YP_002273085.1 209398657 6968672 4627347..4629002 1 NC_011353.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 4629002 lldP 6968672 lldP Escherichia coli O157:H7 str. EC4115 L-lactate permease YP_002273085.1 4627347 D 444450 CDS YP_002273086.1 209395948 6969727 4629002..4629778 1 NC_011353.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4629778 6969727 ECH74115_4977 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor LldR YP_002273086.1 4629002 D 444450 CDS YP_002273087.1 209396531 6966815 4629775..4630965 1 NC_011353.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4630965 lldD 6966815 lldD Escherichia coli O157:H7 str. EC4115 L-lactate dehydrogenase YP_002273087.1 4629775 D 444450 CDS YP_002273088.1 209400099 6967444 4631151..4631624 1 NC_011353.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4631624 6967444 ECH74115_4979 Escherichia coli O157:H7 str. EC4115 tRNA/rRNA methyltransferase YibK YP_002273088.1 4631151 D 444450 CDS YP_002273089.1 209400691 6971281 complement(4631677..4632498) 1 NC_011353.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4632498 cysE 6971281 cysE Escherichia coli O157:H7 str. EC4115 serine acetyltransferase YP_002273089.1 4631677 R 444450 CDS YP_002273090.1 209398298 6971912 complement(4632578..4633597) 1 NC_011353.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4633597 gpsA 6971912 gpsA Escherichia coli O157:H7 str. EC4115 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002273090.1 4632578 R 444450 CDS YP_002273091.1 209398715 6969334 complement(4633597..4634064) 1 NC_011353.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4634064 secB 6969334 secB Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecB YP_002273091.1 4633597 R 444450 CDS YP_002273092.1 209396816 6969787 complement(4634127..4634378) 1 NC_011353.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02181; glutaredoxin 3 4634378 grxC 6969787 grxC Escherichia coli O157:H7 str. EC4115 glutaredoxin 3 YP_002273092.1 4634127 R 444450 CDS YP_002273093.1 209398528 6967748 complement(4634520..4634951) 1 NC_011353.1 identified by match to protein family HMM PF00581; rhodanese domain-containing protein 4634951 6967748 ECH74115_4984 Escherichia coli O157:H7 str. EC4115 rhodanese domain-containing protein YP_002273093.1 4634520 R 444450 CDS YP_002273094.1 209396260 6969587 4635196..4636740 1 NC_011353.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4636740 gpmI 6969587 gpmI Escherichia coli O157:H7 str. EC4115 phosphoglyceromutase YP_002273094.1 4635196 D 444450 CDS YP_002273095.1 209398044 6967153 4636774..4638033 1 NC_011353.1 identified by match to protein family HMM PF01551; hypothetical protein 4638033 6967153 ECH74115_4986 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273095.1 4636774 D 444450 CDS YP_002273096.1 209399753 6969058 4638037..4638996 1 NC_011353.1 identified by match to protein family HMM PF04748; polysaccharide deacetylase family protein 4638996 6969058 ECH74115_4987 Escherichia coli O157:H7 str. EC4115 polysaccharide deacetylase family protein YP_002273096.1 4638037 D 444450 CDS YP_002273097.1 209400006 6967787 complement(4640257..4641282) 1 NC_011353.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4641282 tdh 6967787 tdh Escherichia coli O157:H7 str. EC4115 L-threonine 3-dehydrogenase YP_002273097.1 4640257 R 444450 CDS YP_002273098.1 209396702 6971179 complement(4641292..4642488) 1 NC_011353.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 4642488 kbl 6971179 kbl Escherichia coli O157:H7 str. EC4115 2-amino-3-ketobutyrate coenzyme A ligase YP_002273098.1 4641292 R 444450 CDS YP_002273099.1 209398472 6967626 complement(4642763..4643620) 1 NC_011353.1 identified by match to protein family HMM PF09612; match to protein family HMM TIGR02192; hypothetical protein 4643620 6967626 ECH74115_4991 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273099.1 4642763 R 444450 CDS YP_002273100.1 209400532 6969528 4643924..4644856 1 NC_011353.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4644856 rfaD 6969528 rfaD Escherichia coli O157:H7 str. EC4115 ADP-L-glycero-D-manno-heptose-6-epimerase YP_002273100.1 4643924 D 444450 CDS YP_002273101.1 209398299 6971739 4644866..4645912 1 NC_011353.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4645912 rfaF 6971739 rfaF Escherichia coli O157:H7 str. EC4115 ADP-heptose--LPS heptosyltransferase YP_002273101.1 4644866 D 444450 CDS YP_002273102.1 209399933 6969335 4645916..4646908 1 NC_011353.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193; ADP-heptose--LPS heptosyltransferase 4646908 rfaC 6969335 rfaC Escherichia coli O157:H7 str. EC4115 ADP-heptose--LPS heptosyltransferase YP_002273102.1 4645916 D 444450 CDS YP_002273103.1 209399220 6971098 4646905..4648113 1 NC_011353.1 identified by match to protein family HMM PF04932; lipid A-core:surface polymer ligase 4648113 6971098 ECH74115_4995 Escherichia coli O157:H7 str. EC4115 lipid A-core:surface polymer ligase YP_002273103.1 4646905 D 444450 CDS YP_002273104.1 209400801 6970330 complement(4648149..4649291) 1 NC_011353.1 identified by match to protein family HMM PF00534; lipopolysaccharide 1,2-N-acetylglucosaminetransferase 4649291 6970330 ECH74115_4996 Escherichia coli O157:H7 str. EC4115 lipopolysaccharide 1,2-N-acetylglucosaminetransferase YP_002273104.1 4648149 R 444450 CDS YP_002273105.1 209398034 6972029 complement(4649300..4650313) 1 NC_011353.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,2-glucosyltransferase 4650313 6972029 ECH74115_4997 Escherichia coli O157:H7 str. EC4115 lipopolysaccharide 1,2-glucosyltransferase YP_002273105.1 4649300 R 444450 CDS YP_002273106.1 209397608 6969047 complement(4650338..4650844) 1 NC_011353.1 identified by match to protein family HMM PF06176; lipopolysaccharide core biosynthesis protein 4650844 6969047 ECH74115_4998 Escherichia coli O157:H7 str. EC4115 lipopolysaccharide core biosynthesis protein YP_002273106.1 4650338 R 444450 CDS YP_002273107.1 209396863 6968589 complement(4651071..4652078) 1 NC_011353.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,3-galactosyltransferase 4652078 6968589 ECH74115_4999 Escherichia coli O157:H7 str. EC4115 lipopolysaccharide 1,3-galactosyltransferase YP_002273107.1 4651071 R 444450 CDS YP_002273108.1 209396290 6967798 complement(4652121..4652918) 1 NC_011353.1 identified by match to protein family HMM PF06293; lipopolysaccharide core biosynthesis protein RfaP 4652918 rfaP 6967798 rfaP Escherichia coli O157:H7 str. EC4115 lipopolysaccharide core biosynthesis protein RfaP YP_002273108.1 4652121 R 444450 CDS YP_002273109.1 209399947 6967185 complement(4652911..4654035) 1 NC_011353.1 identified by match to protein family HMM PF00534; lipopolysaccharide core biosynthesis protein RfaG 4654035 rfaG 6967185 rfaG Escherichia coli O157:H7 str. EC4115 lipopolysaccharide core biosynthesis protein RfaG YP_002273109.1 4652911 R 444450 CDS YP_002273110.1 209396360 6971115 complement(4654032..4655090) 1 NC_011353.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02201; lipopolysaccharide core biosynthesis protein 4655090 rfaQ 6971115 rfaQ Escherichia coli O157:H7 str. EC4115 lipopolysaccharide core biosynthesis protein YP_002273110.1 4654032 R 444450 CDS YP_002273111.1 209400697 6967262 4655503..4656780 1 NC_011353.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4656780 waaA 6967262 waaA Escherichia coli O157:H7 str. EC4115 3-deoxy-D-manno-octulosonic-acid transferase YP_002273111.1 4655503 D 444450 CDS YP_002273112.1 209395850 6971920 4656788..4657267 1 NC_011353.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4657267 coaD 6971920 coaD Escherichia coli O157:H7 str. EC4115 phosphopantetheine adenylyltransferase YP_002273112.1 4656788 D 444450 CDS YP_002273113.1 209398868 6966708 complement(4657306..4658115) 1 NC_011353.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4658115 mutM 6966708 mutM Escherichia coli O157:H7 str. EC4115 formamidopyrimidine-DNA glycosylase YP_002273113.1 4657306 R 444450 CDS YP_002273114.1 209400973 6969954 complement(4658213..4658380) 1 NC_011353.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4658380 rpmG 6969954 rpmG Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L33 YP_002273114.1 4658213 R 444450 CDS YP_002273115.1 209397282 6972213 complement(4658401..4658637) 1 NC_011353.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4658637 rpmB 6972213 rpmB Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L28 YP_002273115.1 4658401 R 444450 CDS YP_002273116.1 209399382 6968243 complement(4658854..4659522) 1 NC_011353.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4659522 radC 6968243 radC Escherichia coli O157:H7 str. EC4115 DNA repair protein RadC YP_002273116.1 4658854 R 444450 CDS YP_002273117.1 209395832 6970507 4659622..4660914 1 NC_011353.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4660914 coaBC 6970507 coaBC Escherichia coli O157:H7 str. EC4115 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002273117.1 4659622 D 444450 CDS YP_002273118.1 209396332 6966689 4660892..4661350 1 NC_011353.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4661350 dut 6966689 dut Escherichia coli O157:H7 str. EC4115 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002273118.1 4660892 D 444450 CDS YP_002273119.1 209399917 6967229 4661457..4662053 1 NC_011353.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4662053 slmA 6967229 slmA Escherichia coli O157:H7 str. EC4115 nucleoid occlusion protein YP_002273119.1 4661457 D 444450 CDS YP_002273120.1 209396513 6971081 complement(4662090..4662731) 1 NC_011353.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4662731 pyrE 6971081 pyrE Escherichia coli O157:H7 str. EC4115 orotate phosphoribosyltransferase YP_002273120.1 4662090 R 444450 CDS YP_002273121.1 209399306 6967425 complement(4662797..4663513) 1 NC_011353.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4663513 rph 6967425 rph Escherichia coli O157:H7 str. EC4115 ribonuclease PH YP_002273121.1 4662797 R 444450 CDS YP_002273122.1 209396308 6970423 4663640..4664503 1 NC_011353.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255; hypothetical protein 4664503 6970423 ECH74115_5014 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273122.1 4663640 D 444450 CDS YP_002273123.1 209399724 6967203 complement(4664520..4664660) 1 NC_011353.1 identified by glimmer; hypothetical protein 4664660 6967203 ECH74115_5015 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273123.1 4664520 R 444450 CDS YP_002273124.1 209400472 6970877 4664724..4665548 1 NC_011353.1 DNA-damage-inducible protein D 4665548 dinD 6970877 dinD Escherichia coli O157:H7 str. EC4115 DNA-damage-inducible protein D YP_002273124.1 4664724 D 444450 CDS YP_002273125.1 209398391 6971677 4665840..4666457 1 NC_011353.1 identified by match to protein family HMM PF03458; hypothetical protein 4666457 6971677 ECH74115_5018 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273125.1 4665840 D 444450 CDS YP_002273126.1 209397991 6969435 complement(4666454..4668187) 1 NC_011353.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4668187 ligB 6969435 ligB Escherichia coli O157:H7 str. EC4115 NAD-dependent DNA ligase LigB YP_002273126.1 4666454 R 444450 CDS YP_002273127.1 209396688 6969002 complement(4667997..4668254) 1 NC_011353.1 hypothetical protein 4668254 6969002 ECH74115_5019 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273127.1 4667997 R 444450 CDS YP_002273128.1 209397248 6967610 4668394..4669017 1 NC_011353.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4669017 gmk 6967610 gmk Escherichia coli O157:H7 str. EC4115 guanylate kinase YP_002273128.1 4668394 D 444450 CDS YP_002273129.1 209400040 6968206 4669072..4669347 1 NC_011353.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4669347 rpoZ 6968206 rpoZ Escherichia coli O157:H7 str. EC4115 DNA-directed RNA polymerase subunit omega YP_002273129.1 4669072 D 444450 CDS YP_002273130.1 209400963 6971216 4669366..4671474 1 NC_011353.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4671474 spoT 6971216 spoT Escherichia coli O157:H7 str. EC4115 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_002273130.1 4669366 D 444450 CDS YP_002273131.1 209398863 6972201 4671481..4672170 1 NC_011353.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4672170 trmH 6972201 trmH Escherichia coli O157:H7 str. EC4115 tRNA guanosine-2'-O-methyltransferase YP_002273131.1 4671481 D 444450 CDS YP_002273132.1 209397244 6969949 4672176..4674257 1 NC_011353.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4674257 recG 6969949 recG Escherichia coli O157:H7 str. EC4115 ATP-dependent DNA helicase RecG YP_002273132.1 4672176 D 444450 CDS YP_002273133.1 209399449 6968202 complement(4674242..4675108) 1 NC_011353.1 hypothetical protein 4675108 6968202 ECH74115_5024 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273133.1 4674242 R 444450 CDS YP_002273134.1 209397994 6970578 complement(4675111..4676316) 1 NC_011353.1 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium/glutamate symporter 4676316 gltS 6970578 gltS Escherichia coli O157:H7 str. EC4115 sodium/glutamate symporter YP_002273134.1 4675111 R 444450 CDS YP_002273135.1 209395801 6969005 4676596..4677987 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine permease 4677987 yicE 6969005 yicE Escherichia coli O157:H7 str. EC4115 xanthine permease YP_002273135.1 4676596 D 444450 CDS YP_002273136.1 209396213 6966657 4678108..4679817 1 NC_011353.1 identified by match to protein family HMM PF05170; AsmA family protein 4679817 6966657 ECH74115_5028 Escherichia coli O157:H7 str. EC4115 AsmA family protein YP_002273136.1 4678108 D 444450 CDS YP_002273137.1 209396989 6967102 complement(4679870..4682188) 1 NC_011353.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 4682188 yicI 6967102 yicI Escherichia coli O157:H7 str. EC4115 alpha-xylosidase YP_002273137.1 4679870 R 444450 CDS YP_002273138.1 209400014 6967930 complement(4682198..4683580) 1 NC_011353.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4683580 6967930 ECH74115_5030 Escherichia coli O157:H7 str. EC4115 transporter YP_002273138.1 4682198 R 444450 CDS YP_002273139.1 209400784 6972422 4684091..4685344 1 NC_011353.1 identified by match to protein family HMM PF00589; integrase 4685344 6972422 ECH74115_5032 Escherichia coli O157:H7 str. EC4115 integrase YP_002273139.1 4684091 D 444450 CDS YP_002273140.1 209397454 6972009 4685479..4685793 1 NC_011353.1 identified by match to protein family HMM PF01527; IS911 transposase orfA 4685793 6972009 ECH74115_5033 Escherichia coli O157:H7 str. EC4115 IS911 transposase orfA YP_002273140.1 4685479 D 444450 CDS YP_002273141.1 209398278 6968425 4685913..4686659 1 NC_011353.1 identified by match to protein family HMM PF00665; IS911 transposase orfB 4686659 6968425 ECH74115_5034 Escherichia coli O157:H7 str. EC4115 IS911 transposase orfB YP_002273141.1 4685913 D 444450 CDS YP_002273142.1 209399834 6969311 4686677..4686820 1 NC_011353.1 Aec75 4686820 6969311 ECH74115_5035 Escherichia coli O157:H7 str. EC4115 Aec75 YP_002273142.1 4686677 D 444450 CDS YP_002273143.1 209400366 6970991 4686910..4687284 1 NC_011353.1 identified by match to protein family HMM PF06755; hypothetical protein 4687284 6970991 ECH74115_5036 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273143.1 4686910 D 444450 CDS YP_002273144.1 209398605 6971564 4687281..4687772 1 NC_011353.1 hypothetical protein 4687772 6971564 ECH74115_5037 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273144.1 4687281 D 444450 CDS YP_002273145.1 209396740 6967048 4689403..4689564 1 NC_011353.1 IS66 family element, orf1 4689564 6967048 ECH74115_5041 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf1 YP_002273145.1 4689403 D 444450 CDS YP_002273146.1 209400518 6967666 4689561..4689908 1 NC_011353.1 identified by match to protein family HMM PF05717; IS66 family element, orf2 4689908 6967666 ECH74115_5042 Escherichia coli O157:H7 str. EC4115 IS66 family element, orf2 YP_002273146.1 4689561 D 444450 CDS YP_002273147.1 209399745 6971725 4689958..4691496 1 NC_011353.1 identified by match to protein family HMM PF03050; IS66 family element, transposase 4691496 6971725 ECH74115_5043 Escherichia coli O157:H7 str. EC4115 IS66 family element, transposase YP_002273147.1 4689958 D 444450 CDS YP_002273148.1 209399300 6970901 complement(4691936..4692055) 1 NC_011353.1 identified by glimmer; hypothetical protein 4692055 6970901 ECH74115_5044 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273148.1 4691936 R 444450 CDS YP_002273149.1 209400566 6970416 complement(4692361..4692798) 1 NC_011353.1 identified by match to protein family HMM PF04806; protein EspF 4692798 6970416 ECH74115_5045 Escherichia coli O157:H7 str. EC4115 protein EspF YP_002273149.1 4692361 R 444450 CDS YP_002273150.1 209400345 6971775 4692821..4692973 1 NC_011353.1 identified by glimmer; hypothetical protein 4692973 6971775 ECH74115_5046 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273150.1 4692821 D 444450 CDS YP_002273151.1 209400189 6971543 complement(4693476..4693697) 1 NC_011353.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105; type III secretion apparatus needle protein 4693697 eprI 6971543 eprI Escherichia coli O157:H7 str. EC4115 type III secretion apparatus needle protein YP_002273151.1 4693476 R 444450 CDS YP_002273152.1 209396516 6971376 complement(4693733..4694140) 1 NC_011353.1 hypothetical protein 4694140 6971376 ECH74115_5048 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273152.1 4693733 R 444450 CDS YP_002273153.1 209395770 6967428 complement(4694147..4694941) 1 NC_011353.1 identified by match to protein family HMM PF05802; protein EspB 4694941 6967428 ECH74115_5049 Escherichia coli O157:H7 str. EC4115 protein EspB YP_002273153.1 4694147 R 444450 CDS YP_002273154.1 209398054 6966626 complement(4695106..4696230) 1 NC_011353.1 identified by match to protein family HMM PF04888; protein EspD 4696230 6966626 ECH74115_5050 Escherichia coli O157:H7 str. EC4115 protein EspD YP_002273154.1 4695106 R 444450 CDS YP_002273155.1 209397466 6969069 complement(4696243..4696680) 1 NC_011353.1 identified by match to protein family HMM PF03433; protein EspA 4696680 6969069 ECH74115_5051 Escherichia coli O157:H7 str. EC4115 protein EspA YP_002273155.1 4696243 R 444450 CDS YP_002273156.1 209397108 6968437 complement(4696880..4697935) 1 NC_011353.1 identified by match to protein family HMM PF07018; match to protein family HMM TIGR02511; protein SepL 4697935 6968437 ECH74115_5052 Escherichia coli O157:H7 str. EC4115 protein SepL YP_002273156.1 4696880 R 444450 CDS YP_002273157.1 209399186 6968057 4698078..4699298 1 NC_011353.1 identified by match to protein family HMM TIGR02500; type III secretion apparatus protein, YscD/HrpQ family 4699298 6968057 ECH74115_5053 Escherichia coli O157:H7 str. EC4115 type III secretion apparatus protein, YscD/HrpQ family YP_002273157.1 4698078 D 444450 CDS YP_002273158.1 209398935 6970294 complement(4699562..4702366) 1 NC_011353.1 identified by match to protein family HMM PF01476; match to protein family HMM PF02368; match to protein family HMM PF02369; match to protein family HMM PF07979; intimin C-type lectin domain-containing protein 4702366 6970294 ECH74115_5054 Escherichia coli O157:H7 str. EC4115 intimin C-type lectin domain-containing protein YP_002273158.1 4699562 R 444450 CDS YP_002273159.1 209398182 6970029 complement(4702426..4702896) 1 NC_011353.1 identified by match to protein family HMM PF05932; Tir chaperone 4702896 6970029 ECH74115_5055 Escherichia coli O157:H7 str. EC4115 Tir chaperone YP_002273159.1 4702426 R 444450 CDS YP_002273160.1 209397995 6969208 complement(4703034..4704710) 1 NC_011353.1 identified by match to protein family HMM PF03549; match to protein family HMM PF07489; match to protein family HMM PF07490; Tir 4704710 6969208 ECH74115_5056 Escherichia coli O157:H7 str. EC4115 Tir YP_002273160.1 4703034 R 444450 CDS YP_002273161.1 209397062 6969006 complement(4705134..4705619) 1 NC_011353.1 identified by match to protein family HMM PF03278; Map protein 4705619 6969006 ECH74115_5057 Escherichia coli O157:H7 str. EC4115 Map protein YP_002273161.1 4705134 R 444450 CDS YP_002273162.1 209399488 6968008 4706011..4706394 1 NC_011353.1 hypothetical protein 4706394 6968008 ECH74115_5058 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273162.1 4706011 D 444450 CDS YP_002273163.1 209398744 6970622 complement(4706592..4707098) 1 NC_011353.1 hypothetical protein 4707098 6970622 ECH74115_5059 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273163.1 4706592 R 444450 CDS YP_002273164.1 209400927 6969820 complement(4707129..4708046) 1 NC_011353.1 protein SepQ 4708046 6969820 ECH74115_5060 Escherichia coli O157:H7 str. EC4115 protein SepQ YP_002273164.1 4707129 R 444450 CDS YP_002273165.1 209400182 6972164 complement(4708418..4708738) 1 NC_011353.1 ST25 protein 4708738 6972164 ECH74115_5061 Escherichia coli O157:H7 str. EC4115 ST25 protein YP_002273165.1 4708418 R 444450 CDS YP_002273166.1 209396453 6971369 complement(4708798..4710138) 1 NC_011353.1 identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546; type III secretion apparatus H+-transporting two-sector ATPase 4710138 6971369 ECH74115_5062 Escherichia coli O157:H7 str. EC4115 type III secretion apparatus H+-transporting two-sector ATPase YP_002273166.1 4708798 R 444450 CDS YP_002273167.1 209395993 6967364 complement(4710122..4712149) 1 NC_011353.1 identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399; type III secretion protein, HrcV family 4712149 6967364 ECH74115_5063 Escherichia coli O157:H7 str. EC4115 type III secretion protein, HrcV family YP_002273167.1 4710122 R 444450 CDS YP_002273168.1 209397924 6966864 complement(4712146..4712499) 1 NC_011353.1 ST22 protein 4712499 6966864 ECH74115_5064 Escherichia coli O157:H7 str. EC4115 ST22 protein YP_002273168.1 4712146 R 444450 CDS YP_002273169.1 209399589 6968924 complement(4712662..4712805) 1 NC_011353.1 identified by glimmer; hypothetical protein 4712805 6968924 ECH74115_5065 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273169.1 4712662 R 444450 CDS YP_002273170.1 209399518 6970730 4713447..4714019 1 NC_011353.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544; type III secretion apparatus lipoprotein, YscJ/HrcJ family 4714019 6970730 ECH74115_5066 Escherichia coli O157:H7 str. EC4115 type III secretion apparatus lipoprotein, YscJ/HrcJ family YP_002273170.1 4713447 D 444450 CDS YP_002273171.1 209400098 6970654 complement(4714175..4714336) 1 NC_011353.1 identified by glimmer; hypothetical protein 4714336 6970654 ECH74115_5067 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273171.1 4714175 R 444450 CDS YP_002273172.1 209400690 6971280 4714361..4714480 1 NC_011353.1 protein SepD 4714480 6971280 ECH74115_5068 Escherichia coli O157:H7 str. EC4115 protein SepD YP_002273172.1 4714361 D 444450 CDS YP_002273173.1 209395836 6971911 4714480..4716018 1 NC_011353.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516; type III secretion outer membrane pore, YscC/HrcC family 4716018 6971911 ECH74115_5069 Escherichia coli O157:H7 str. EC4115 type III secretion outer membrane pore, YscC/HrcC family YP_002273173.1 4714480 D 444450 CDS YP_002273174.1 209397075 6966693 complement(4717339..4717710) 1 NC_011353.1 negative regulator GrlR 4717710 6966693 ECH74115_5070 Escherichia coli O157:H7 str. EC4115 negative regulator GrlR YP_002273174.1 4717339 R 444450 CDS YP_002273175.1 209398775 6968021 4717906..4718364 1 NC_011353.1 identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 4718364 6968021 ECH74115_5072 Escherichia coli O157:H7 str. EC4115 transglycosylase SLT domain-containing protein YP_002273175.1 4717906 D 444450 CDS YP_002273176.1 209398003 6969853 complement(4718361..4719398) 1 NC_011353.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli; secretion system apparatus protein SsaU 4719398 6969853 ECH74115_5071 Escherichia coli O157:H7 str. EC4115 secretion system apparatus protein SsaU YP_002273176.1 4718361 R 444450 CDS YP_002273177.1 209399341 6969015 complement(4719391..4720167) 1 NC_011353.1 identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401; type III secretion apparatus protein SpaR/YscT/HrcT 4720167 epaR 6969015 epaR Escherichia coli O157:H7 str. EC4115 type III secretion apparatus protein SpaR/YscT/HrcT YP_002273177.1 4719391 R 444450 CDS YP_002273178.1 209400714 6970461 complement(4720167..4720292) 1 NC_011353.1 EscS protein 4720292 6970461 ECH74115_5074 Escherichia coli O157:H7 str. EC4115 EscS protein YP_002273178.1 4720167 R 444450 CDS YP_002273179.1 209398112 6971938 complement(4720436..4721089) 1 NC_011353.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein 4721089 epaP 6971938 epaP Escherichia coli O157:H7 str. EC4115 type III secretion system protein YP_002273179.1 4720436 R 444450 CDS YP_002273180.1 209399172 6969131 complement(4721094..4721747) 1 NC_011353.1 hypothetical protein 4721747 6969131 ECH74115_5076 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273180.1 4721094 R 444450 CDS YP_002273181.1 209399924 6970280 complement(4721734..4721877) 1 NC_011353.1 hypothetical protein 4721877 6970280 ECH74115_5077 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273181.1 4721734 R 444450 CDS YP_002273182.1 209400330 6971088 complement(4722330..4722644) 1 NC_011353.1 hypothetical protein 4722644 6971088 ECH74115_5078 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273182.1 4722330 R 444450 CDS YP_002273183.1 209400487 6971526 complement(4722657..4722875) 1 NC_011353.1 identified by match to protein family HMM TIGR02501; type III secretion system protein, YseE family 4722875 6971526 ECH74115_5079 Escherichia coli O157:H7 str. EC4115 type III secretion system protein, YseE family YP_002273183.1 4722657 R 444450 CDS YP_002273184.1 209396252 6971692 complement(4722890..4723261) 1 NC_011353.1 identified by match to protein family HMM PF00816; hypothetical protein 4723261 6971692 ECH74115_5080 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273184.1 4722890 R 444450 CDS YP_002273185.1 209396719 6967145 4724575..4725720 1 NC_011353.1 identified by match to protein family HMM PF06872; protein EspG 4725720 6967145 ECH74115_5081 Escherichia coli O157:H7 str. EC4115 protein EspG YP_002273185.1 4724575 D 444450 CDS YP_002273186.1 209397482 6967645 4725848..4726666 1 NC_011353.1 identified by match to protein family HMM PF06977; sdiA-regulated domain-containing protein 4726666 6967645 ECH74115_5082 Escherichia coli O157:H7 str. EC4115 sdiA-regulated domain-containing protein YP_002273186.1 4725848 D 444450 CDS YP_002273187.1 209397489 6968453 complement(4727060..4727173) 1 NC_011353.1 identified by glimmer; hypothetical protein 4727173 6968453 ECH74115_5083 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273187.1 4727060 R 444450 CDS YP_002273188.1 209398567 6968460 complement(4727438..4727623) 1 NC_011353.1 hypothetical protein 4727623 6968460 ECH74115_5084 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273188.1 4727438 R 444450 CDS YP_002273189.1 209397051 6969628 4727686..4728609 1 NC_011353.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; carboxylate/amino acid/amine transporter 4728609 6969628 ECH74115_5085 Escherichia coli O157:H7 str. EC4115 carboxylate/amino acid/amine transporter YP_002273189.1 4727686 D 444450 CDS YP_002273190.1 209399316 6967997 complement(4728613..4729431) 1 NC_011353.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; hypothetical protein 4729431 nlpA 6967997 nlpA Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273190.1 4728613 R 444450 CDS YP_002273191.1 209399558 6970435 complement(4729428..4729571) 1 NC_011353.1 hypothetical protein 4729571 6970435 ECH74115_5087 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273191.1 4729428 R 444450 CDS YP_002273192.1 209400485 6970696 4729653..4729946 1 NC_011353.1 hypothetical protein 4729946 6970696 ECH74115_5088 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273192.1 4729653 D 444450 CDS YP_002273193.1 209400299 6972025 4731411..4731764 1 NC_011353.1 identified by match to protein family HMM PF06296; hypothetical protein 4731764 6972025 ECH74115_5090 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273193.1 4731411 D 444450 CDS YP_002273194.1 209398116 6971493 4731748..4732071 1 NC_011353.1 identified by match to protein family HMM PF01381; DNA-binding protein 4732071 6971493 ECH74115_5091 Escherichia coli O157:H7 str. EC4115 DNA-binding protein YP_002273194.1 4731748 D 444450 CDS YP_002273195.1 209397416 6969135 complement(4732187..4732639) 1 NC_011353.1 identified by match to protein family HMM PF06711; hypothetical protein 4732639 6969135 ECH74115_5092 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273195.1 4732187 R 444450 CDS YP_002273196.1 209400507 6969467 4734200..4735966 1 NC_011353.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4735966 ade 6969467 ade Escherichia coli O157:H7 str. EC4115 cryptic adenine deaminase YP_002273196.1 4734200 D 444450 CDS YP_002273197.1 209396223 6971712 complement(4736012..4737403) 1 NC_011353.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4737403 uhpT 6971712 uhpT Escherichia coli O157:H7 str. EC4115 sugar phosphate antiporter YP_002273197.1 4736012 R 444450 CDS YP_002273198.1 209396606 6967113 complement(4737541..4738860) 1 NC_011353.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4738860 uhpC 6967113 uhpC Escherichia coli O157:H7 str. EC4115 regulatory protein UhpC YP_002273198.1 4737541 R 444450 CDS YP_002273199.1 209397016 6967523 complement(4738870..4740375) 1 NC_011353.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4740375 uhpB 6967523 uhpB Escherichia coli O157:H7 str. EC4115 sensory histidine kinase UhpB YP_002273199.1 4738870 R 444450 CDS YP_002273200.1 209398144 6967960 complement(4740372..4740962) 1 NC_011353.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4740962 uhpA 6967960 uhpA Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator UhpA YP_002273200.1 4740372 R 444450 CDS YP_002273201.1 209395791 6971263 complement(4744381..4744671) 1 NC_011353.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4744671 ilvN 6971263 ilvN Escherichia coli O157:H7 str. EC4115 acetolactate synthase 1 regulatory subunit YP_002273201.1 4744381 R 444450 CDS YP_002273202.1 209396868 6966647 complement(4744675..4746363) 1 NC_011353.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase catalytic subunit 4746363 ilvB 6966647 ilvB Escherichia coli O157:H7 str. EC4115 acetolactate synthase catalytic subunit YP_002273202.1 4744675 R 444450 CDS YP_002273203.1 209396441 6967803 4747495..4748685 1 NC_011353.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4748685 emrD 6967803 emrD Escherichia coli O157:H7 str. EC4115 multidrug resistance protein D YP_002273203.1 4747495 D 444450 CDS YP_002273204.1 209395887 6967351 complement(4748693..4749190) 1 NC_011353.1 hypothetical protein 4749190 6967351 ECH74115_5106 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273204.1 4748693 R 444450 CDS YP_002273205.1 209400764 6966751 complement(4749187..4749549) 1 NC_011353.1 hypothetical protein 4749549 6966751 ECH74115_5107 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273205.1 4749187 R 444450 CDS YP_002273206.1 209400047 6971989 complement(4749539..4749886) 1 NC_011353.1 identified by match to protein family HMM PF02656; hypothetical protein 4749886 6971989 ECH74115_5108 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273206.1 4749539 R 444450 CDS YP_002273207.1 209399592 6971224 4749995..4750444 1 NC_011353.1 hypothetical protein 4750444 6971224 ECH74115_5109 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273207.1 4749995 D 444450 CDS YP_002273208.1 209399130 6970733 complement(4750491..4751984) 1 NC_011353.1 identified by match to protein family HMM PF00884; sulfatase 4751984 6970733 ECH74115_5110 Escherichia coli O157:H7 str. EC4115 sulfatase YP_002273208.1 4750491 R 444450 CDS YP_002273209.1 209399812 6970232 complement(4751981..4753696) 1 NC_011353.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4753696 6970232 ECH74115_5111 Escherichia coli O157:H7 str. EC4115 symporter YidK YP_002273209.1 4751981 R 444450 CDS YP_002273210.1 209399012 6970969 4753863..4754756 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4754756 6970969 ECH74115_5113 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002273210.1 4753863 D 444450 CDS YP_002273211.1 209396857 6970112 complement(4754753..4756075) 1 NC_011353.1 identified by match to protein family HMM PF02056; maltose-6'-phosphate glucosidase 4756075 glvA 6970112 glvA Escherichia coli O157:H7 str. EC4115 maltose-6'-phosphate glucosidase YP_002273211.1 4754753 R 444450 CDS YP_002273212.1 209400134 6967792 complement(4756075..4757691) 1 NC_011353.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005; PTS system, alpha-glucoside-specific transporter subunit IIBC 4757691 6967792 ECH74115_5114 Escherichia coli O157:H7 str. EC4115 PTS system, alpha-glucoside-specific transporter subunit IIBC YP_002273212.1 4756075 R 444450 CDS YP_002273213.1 209396933 6971320 4757987..4758703 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4758703 6971320 ECH74115_5116 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002273213.1 4757987 D 444450 CDS YP_002273214.1 209396187 6967871 complement(4758700..4760385) 1 NC_011353.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein 4760385 6967871 ECH74115_5115 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273214.1 4758700 R 444450 CDS YP_002273215.1 209397580 6967074 4760403..4760552 1 NC_011353.1 identified by glimmer; hypothetical protein 4760552 6967074 ECH74115_5117 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273215.1 4760403 D 444450 CDS YP_002273216.1 209395818 6968557 complement(4760557..4760985) 1 NC_011353.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4760985 ibpB 6968557 ibpB Escherichia coli O157:H7 str. EC4115 heat shock chaperone IbpB YP_002273216.1 4760557 R 444450 CDS YP_002273217.1 209399295 6966675 complement(4761097..4761510) 1 NC_011353.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4761510 ibpA 6966675 ibpA Escherichia coli O157:H7 str. EC4115 heat shock protein IbpA YP_002273217.1 4761097 R 444450 CDS YP_002273218.1 209397065 6970411 complement(4761770..4761928) 1 NC_011353.1 hypothetical protein 4761928 6970411 ECH74115_5120 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273218.1 4761770 R 444450 CDS YP_002273219.1 209400457 6968011 4761888..4762148 1 NC_011353.1 identified by match to protein family HMM PF07119; hypothetical protein 4762148 6968011 ECH74115_5121 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273219.1 4761888 D 444450 CDS YP_002273220.1 209398871 6971662 complement(4762150..4763400) 1 NC_011353.1 hypothetical protein 4763400 6971662 ECH74115_5122 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273220.1 4762150 R 444450 CDS YP_002273221.1 209398169 6969957 4763465..4764529 1 NC_011353.1 FAD/NAD(P)-binding domain; oxidoreductase 4764529 6969957 ECH74115_5123 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002273221.1 4763465 D 444450 CDS YP_002273222.1 209395907 6969194 4764775..4765431 1 NC_011353.1 identified by glimmer; hypothetical protein 4765431 6969194 ECH74115_5124 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273222.1 4764775 D 444450 CDS YP_002273223.1 209398934 6966773 complement(4765477..4766289) 1 NC_011353.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4766289 yidA 6966773 yidA Escherichia coli O157:H7 str. EC4115 sugar phosphatase YP_002273223.1 4765477 R 444450 CDS YP_002273224.1 209399342 6970028 complement(4766404..4766802) 1 NC_011353.1 identified by match to protein family HMM PF06078; hypothetical protein 4766802 6970028 ECH74115_5126 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273224.1 4766404 R 444450 CDS YP_002273225.1 209396545 6970462 complement(4767042..4769459) 1 NC_011353.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4769459 gyrB 6970462 gyrB Escherichia coli O157:H7 str. EC4115 DNA gyrase subunit B YP_002273225.1 4767042 R 444450 CDS YP_002273226.1 209397495 6967459 complement(4769485..4770558) 1 NC_011353.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4770558 recF 6967459 recF Escherichia coli O157:H7 str. EC4115 recombination protein F YP_002273226.1 4769485 R 444450 CDS YP_002273227.1 209400437 6968467 complement(4770558..4771658) 1 NC_011353.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4771658 dnaN 6968467 dnaN Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit beta YP_002273227.1 4770558 R 444450 CDS YP_002273228.1 209395729 6971639 complement(4771663..4773066) 1 NC_011353.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 4773066 dnaA 6971639 dnaA Escherichia coli O157:H7 str. EC4115 chromosomal replication initiation protein YP_002273228.1 4771663 R 444450 CDS YP_002273229.1 209397272 6966584 complement(4773360..4773560) 1 NC_011353.1 identified by glimmer; hypothetical protein 4773560 6966584 ECH74115_5131 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273229.1 4773360 R 444450 CDS YP_002273230.1 209397751 6968232 complement(4773580..4773720) 1 NC_011353.1 identified by glimmer; hypothetical protein 4773720 6968232 ECH74115_5132 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273230.1 4773580 R 444450 CDS YP_002273231.1 209396814 6968738 4773673..4773813 1 NC_011353.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4773813 rpmH 6968738 rpmH Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L34 YP_002273231.1 4773673 D 444450 CDS YP_002273232.1 209396527 6967746 4773830..4774189 1 NC_011353.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4774189 rnpA 6967746 rnpA Escherichia coli O157:H7 str. EC4115 ribonuclease P YP_002273232.1 4773830 D 444450 CDS YP_002273233.1 209400160 6967440 4774413..4776059 1 NC_011353.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4776059 6967440 ECH74115_5135 Escherichia coli O157:H7 str. EC4115 inner membrane protein translocase component YidC YP_002273233.1 4774413 D 444450 CDS YP_002273234.1 209395938 6971346 4776165..4777529 1 NC_011353.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4777529 trmE 6971346 trmE Escherichia coli O157:H7 str. EC4115 tRNA modification GTPase TrmE YP_002273234.1 4776165 D 444450 CDS YP_002273235.1 209400950 6969763 complement(4777860..4779848) 1 NC_011353.1 identified by match to protein family HMM PF07906; ShET2 enterotoxin, N- region family 4779848 6969763 ECH74115_5138 Escherichia coli O157:H7 str. EC4115 ShET2 enterotoxin, N- region family YP_002273235.1 4777860 R 444450 CDS YP_002273236.1 209397514 6972188 4780534..4781949 1 NC_011353.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4781949 tnaA 6972188 tnaA Escherichia coli O157:H7 str. EC4115 tryptophanase YP_002273236.1 4780534 D 444450 CDS YP_002273237.1 209399599 6968487 4782040..4783287 1 NC_011353.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4783287 tnaB 6968487 tnaB Escherichia coli O157:H7 str. EC4115 tryptophan permease TnaB YP_002273237.1 4782040 D 444450 CDS YP_002273238.1 209395703 6970740 4783419..4784594 1 NC_011353.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4784594 mdtL 6970740 mdtL Escherichia coli O157:H7 str. EC4115 multidrug efflux system protein MdtL YP_002273238.1 4783419 D 444450 CDS YP_002273239.1 209397765 6966557 4784569..4785528 1 NC_011353.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4785528 6966557 ECH74115_5142 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator YidZ YP_002273239.1 4784569 D 444450 CDS YP_002273240.1 209398815 6968753 4785685..4786434 1 NC_011353.1 hypothetical protein 4786434 6968753 ECH74115_5143 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273240.1 4785685 D 444450 CDS YP_002273241.1 209400915 6969895 4786456..4787022 1 NC_011353.1 identified by match to protein family HMM PF03358; NADPH-dependent FMN reductase 4787022 6969895 ECH74115_5144 Escherichia coli O157:H7 str. EC4115 NADPH-dependent FMN reductase YP_002273241.1 4786456 D 444450 CDS YP_002273242.1 209399820 6972151 complement(4787076..4788413) 1 NC_011353.1 identified by match to protein family HMM PF00860; inorganic anion transporter sulfate permease (SulP) family 4788413 6972151 ECH74115_5145 Escherichia coli O157:H7 str. EC4115 inorganic anion transporter sulfate permease (SulP) family YP_002273242.1 4787076 R 444450 CDS YP_002273243.1 209396591 6970977 4788579..4789244 1 NC_011353.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4789244 6970977 ECH74115_5146 Escherichia coli O157:H7 str. EC4115 6-phosphogluconate phosphatase YP_002273243.1 4788579 D 444450 CDS YP_002273244.1 209399167 6967506 complement(4789381..4791789) 1 NC_011353.1 identified by glimmer; hypothetical protein 4791789 6967506 ECH74115_5147 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273244.1 4789381 R 444450 CDS YP_002273245.1 209398058 6969692 4793110..4793277 1 NC_011353.1 hypothetical protein 4793277 6969692 ECH74115_5149 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273245.1 4793110 D 444450 CDS YP_002273246.1 209397340 6969073 complement(4793376..4793555) 1 NC_011353.1 hypothetical protein 4793555 6969073 ECH74115_5150 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273246.1 4793376 R 444450 CDS YP_002273247.1 209396628 6969366 complement(4796656..4797381) 1 NC_011353.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4797381 phoU 6969366 phoU Escherichia coli O157:H7 str. EC4115 transcriptional regulator PhoU YP_002273247.1 4796656 R 444450 CDS YP_002273248.1 209395842 6967548 complement(4797396..4798169) 1 NC_011353.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4798169 pstB 6967548 pstB Escherichia coli O157:H7 str. EC4115 phosphate transporter ATP-binding protein YP_002273248.1 4797396 R 444450 CDS YP_002273249.1 209400595 6966699 complement(4798352..4799242) 1 NC_011353.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4799242 pstA 6966699 pstA Escherichia coli O157:H7 str. EC4115 phosphate transporter permease subunit PtsA YP_002273249.1 4798352 R 444450 CDS YP_002273250.1 209399381 6971806 complement(4799242..4800201) 1 NC_011353.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4800201 pstC 6971806 pstC Escherichia coli O157:H7 str. EC4115 phosphate transporter permease subunit PstC YP_002273250.1 4799242 R 444450 CDS YP_002273251.1 209400241 6970506 complement(4800288..4801328) 1 NC_011353.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter substrate-binding protein 4801328 pstS 6970506 pstS Escherichia coli O157:H7 str. EC4115 phosphate ABC transporter substrate-binding protein YP_002273251.1 4800288 R 444450 CDS YP_002273252.1 209401000 6971431 4801395..4801511 1 NC_011353.1 identified by glimmer; hypothetical protein 4801511 6971431 ECH74115_5158 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273252.1 4801395 D 444450 CDS YP_002273253.1 209398343 6972242 complement(4801540..4802622) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial family protein 4802622 6972242 ECH74115_5159 Escherichia coli O157:H7 str. EC4115 fimbrial family protein YP_002273253.1 4801540 R 444450 CDS YP_002273254.1 209395769 6969383 complement(4802650..4803720) 1 NC_011353.1 fimbrial protein 4803720 6969383 ECH74115_5160 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002273254.1 4802650 R 444450 CDS YP_002273255.1 209397496 6966625 complement(4803732..4806266) 1 NC_011353.1 identified by match to protein family HMM PF00577; fimbrial usher protein 4806266 6966625 ECH74115_5161 Escherichia coli O157:H7 str. EC4115 fimbrial usher protein YP_002273255.1 4803732 R 444450 CDS YP_002273256.1 209400508 6971091 complement(4807077..4807679) 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein 4807679 6971091 ECH74115_5164 Escherichia coli O157:H7 str. EC4115 fimbrial protein YP_002273256.1 4807077 R 444450 CDS YP_002273257.1 209397586 6971713 complement(4808379..4810208) 1 NC_011353.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4810208 glmS 6971713 glmS Escherichia coli O157:H7 str. EC4115 glucosamine--fructose-6-phosphate aminotransferase YP_002273257.1 4808379 R 444450 CDS YP_002273258.1 209399085 6968564 complement(4810370..4811740) 1 NC_011353.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4811740 glmU 6968564 glmU Escherichia coli O157:H7 str. EC4115 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002273258.1 4810370 R 444450 CDS YP_002273259.1 209399630 6970187 complement(4812092..4812511) 1 NC_011353.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 4812511 atpC 6970187 atpC Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit epsilon YP_002273259.1 4812092 R 444450 CDS YP_002273260.1 209400614 6970775 complement(4812532..4813914) 1 NC_011353.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4813914 atpD 6970775 atpD Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit beta YP_002273260.1 4812532 R 444450 CDS YP_002273261.1 209399875 6971826 complement(4813941..4814804) 1 NC_011353.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4814804 atpG 6971826 atpG Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit gamma YP_002273261.1 4813941 R 444450 CDS YP_002273262.1 209400618 6971034 complement(4814855..4816396) 1 NC_011353.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 4816396 atpA 6971034 atpA Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit alpha YP_002273262.1 4814855 R 444450 CDS YP_002273263.1 209396631 6971830 complement(4816409..4816942) 1 NC_011353.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4816942 atpH 6971830 atpH Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit delta YP_002273263.1 4816409 R 444450 CDS YP_002273264.1 209396106 6967551 complement(4816957..4817427) 1 NC_011353.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 4817427 atpF 6967551 atpF Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit B YP_002273264.1 4816957 R 444450 CDS YP_002273265.1 209398175 6966985 complement(4817489..4817728) 1 NC_011353.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 4817728 atpE 6966985 atpE Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit C YP_002273265.1 4817489 R 444450 CDS YP_002273266.1 209397175 6969200 complement(4817775..4818590) 1 NC_011353.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4818590 atpB 6969200 atpB Escherichia coli O157:H7 str. EC4115 F0F1 ATP synthase subunit A YP_002273266.1 4817775 R 444450 CDS YP_002273267.1 209398780 6968128 complement(4818599..4818817) 1 NC_011353.1 identified by match to protein family HMM PF03899; ATP synthase F0, I subunit 4818817 atpI 6968128 atpI Escherichia coli O157:H7 str. EC4115 ATP synthase F0, I subunit YP_002273267.1 4818599 R 444450 CDS YP_002273268.1 209399374 6969858 complement(4819596..4820219) 1 NC_011353.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4820219 gidB 6969858 gidB Escherichia coli O157:H7 str. EC4115 16S rRNA methyltransferase GidB YP_002273268.1 4819596 R 444450 CDS YP_002273269.1 209400287 6970499 complement(4820283..4822172) 1 NC_011353.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4822172 gidA 6970499 gidA Escherichia coli O157:H7 str. EC4115 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002273269.1 4820283 R 444450 CDS YP_002273270.1 209400883 6971481 complement(4822551..4822994) 1 NC_011353.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4822994 mioC 6971481 mioC Escherichia coli O157:H7 str. EC4115 flavodoxin YP_002273270.1 4822551 R 444450 CDS YP_002273271.1 209399222 6972116 complement(4823084..4823542) 1 NC_011353.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4823542 asnC 6972116 asnC Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator AsnC YP_002273271.1 4823084 R 444450 CDS YP_002273272.1 209399484 6970332 4823694..4824686 1 NC_011353.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4824686 asnA 6970332 asnA Escherichia coli O157:H7 str. EC4115 asparagine synthetase AsnA YP_002273272.1 4823694 D 444450 CDS YP_002273273.1 209397934 6970618 complement(4824691..4826142) 1 NC_011353.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4826142 yieM 6970618 yieM Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273273.1 4824691 R 444450 CDS YP_002273274.1 209398514 6968935 complement(4826136..4827632) 1 NC_011353.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4827632 6968935 ECH74115_5182 Escherichia coli O157:H7 str. EC4115 regulatory ATPase RavA YP_002273274.1 4826136 R 444450 CDS YP_002273275.1 209396878 6969572 4827855..4829723 1 NC_011353.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4829723 trkD 6969572 trkD Escherichia coli O157:H7 str. EC4115 potassium transport protein Kup YP_002273275.1 4827855 D 444450 CDS YP_002273276.1 209397170 6967815 4829890..4830309 1 NC_011353.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4830309 rbsD 6967815 rbsD Escherichia coli O157:H7 str. EC4115 D-ribose pyranase YP_002273276.1 4829890 D 444450 CDS YP_002273277.1 209400209 6968123 4830317..4831822 1 NC_011353.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4831822 rbsA 6968123 rbsA Escherichia coli O157:H7 str. EC4115 D-ribose transporter ATP-binding protein YP_002273277.1 4830317 D 444450 CDS YP_002273278.1 209396828 6971397 4831827..4832792 1 NC_011353.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4832792 rbsC 6971397 rbsC Escherichia coli O157:H7 str. EC4115 ribose ABC transporter permease YP_002273278.1 4831827 D 444450 CDS YP_002273279.1 209400606 6967761 4832817..4833707 1 NC_011353.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4833707 rbsB 6967761 rbsB Escherichia coli O157:H7 str. EC4115 D-ribose transporter subunit RbsB YP_002273279.1 4832817 D 444450 CDS YP_002273280.1 209398689 6971818 4833818..4834762 1 NC_011353.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4834762 rbsK 6971818 rbsK Escherichia coli O157:H7 str. EC4115 ribokinase YP_002273280.1 4833818 D 444450 CDS YP_002273281.1 209400180 6969759 4834766..4835758 1 NC_011353.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4835758 rbsR 6969759 rbsR Escherichia coli O157:H7 str. EC4115 transcriptional repressor RbsR YP_002273281.1 4834766 D 444450 CDS YP_002273282.1 209397220 6971367 complement(4835724..4837151) 1 NC_011353.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; drug resistance MFS transporter drug:H+ antiporter-1 (DHA2) family 4837151 6971367 ECH74115_5189 Escherichia coli O157:H7 str. EC4115 drug resistance MFS transporter drug:H+ antiporter-1 (DHA2) family YP_002273282.1 4835724 R 444450 CDS YP_002273283.1 209398283 6968178 complement(4837174..4837866) 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 4837866 6968178 ECH74115_5191 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002273283.1 4837174 R 444450 CDS YP_002273284.1 209397148 6972346 complement(4843669..4844508) 1 NC_011353.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4844508 hdfR 6972346 hdfR Escherichia coli O157:H7 str. EC4115 transcriptional regulator HdfR YP_002273284.1 4843669 R 444450 CDS YP_002273285.1 209397878 6968100 4844627..4844965 1 NC_011353.1 identified by match to protein family HMM PF04219; hypothetical protein 4844965 6968100 ECH74115_5200 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273285.1 4844627 D 444450 CDS YP_002273286.1 209397578 6968874 complement(4844989..4846509) 1 NC_011353.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 4846509 6968874 ECH74115_5201 Escherichia coli O157:H7 str. EC4115 ATP-dependent protease YP_002273286.1 4844989 R 444450 CDS YP_002273287.1 209398313 6968555 4847100..4848746 1 NC_011353.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4848746 ilvG 6968555 ilvG Escherichia coli O157:H7 str. EC4115 acetolactate synthase 2 catalytic subunit YP_002273287.1 4847100 D 444450 CDS YP_002273288.1 209396078 6969351 4848743..4849006 1 NC_011353.1 acetolactate synthase 2 regulatory subunit 4849006 ilvM 6969351 ilvM Escherichia coli O157:H7 str. EC4115 acetolactate synthase 2 regulatory subunit YP_002273288.1 4848743 D 444450 CDS YP_002273289.1 209396780 6966957 4849026..4849955 1 NC_011353.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4849955 ilvE 6966957 ilvE Escherichia coli O157:H7 str. EC4115 branched-chain amino acid aminotransferase YP_002273289.1 4849026 D 444450 CDS YP_002273290.1 209397588 6967710 4850020..4851870 1 NC_011353.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4851870 ilvD 6967710 ilvD Escherichia coli O157:H7 str. EC4115 dihydroxy-acid dehydratase YP_002273290.1 4850020 D 444450 CDS YP_002273291.1 209398269 6968566 4851873..4853417 1 NC_011353.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4853417 ilvA 6968566 ilvA Escherichia coli O157:H7 str. EC4115 threonine dehydratase YP_002273291.1 4851873 D 444450 CDS YP_002273292.1 209399024 6969301 complement(4853469..4854362) 1 NC_011353.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4854362 ilvY 6969301 ilvY Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator IlvY YP_002273292.1 4853469 R 444450 CDS YP_002273293.1 209397121 6970124 4854512..4855987 1 NC_011353.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4855987 ilvC 6970124 ilvC Escherichia coli O157:H7 str. EC4115 ketol-acid reductoisomerase YP_002273293.1 4854512 D 444450 CDS YP_002273294.1 209400598 6968070 complement(4856033..4856314) 1 NC_011353.1 identified by match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase C 4856314 ppiC 6968070 ppiC Escherichia coli O157:H7 str. EC4115 peptidyl-prolyl cis-trans isomerase C YP_002273294.1 4856033 R 444450 CDS YP_002273295.1 209398694 6971809 complement(4856513..4856962) 1 NC_011353.1 hypothetical protein 4856962 6971809 ECH74115_5210 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273295.1 4856513 R 444450 CDS YP_002273296.1 209398850 6969766 4857179..4859200 1 NC_011353.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4859200 rep 6969766 rep Escherichia coli O157:H7 str. EC4115 ATP-dependent DNA helicase Rep YP_002273296.1 4857179 D 444450 CDS YP_002273297.1 209397791 6969935 complement(4859247..4860731) 1 NC_011353.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4860731 gppA 6969935 gppA Escherichia coli O157:H7 str. EC4115 guanosine pentaphosphate phosphohydrolase YP_002273297.1 4859247 R 444450 CDS YP_002273298.1 209397506 6968780 complement(4860867..4862132) 1 NC_011353.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4862132 rhlB 6968780 rhlB Escherichia coli O157:H7 str. EC4115 ATP-dependent RNA helicase RhlB YP_002273298.1 4860867 R 444450 CDS YP_002273299.1 209396946 6968478 4862263..4862592 1 NC_011353.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 4862592 trxA 6968478 trxA Escherichia coli O157:H7 str. EC4115 thioredoxin YP_002273299.1 4862263 D 444450 CDS YP_002273300.1 209400658 6967884 4862919..4864178 1 NC_011353.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4864178 rho 6967884 rho Escherichia coli O157:H7 str. EC4115 transcription termination factor Rho YP_002273300.1 4862919 D 444450 CDS YP_002273301.1 209400741 6971874 4864212..4864406 1 NC_011353.1 identified by glimmer; hypothetical protein 4864406 6971874 ECH74115_5216 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273301.1 4864212 D 444450 CDS YP_002273302.1 209400540 6971966 4864418..4865521 1 NC_011353.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 4865521 wecA 6971966 wecA Escherichia coli O157:H7 str. EC4115 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_002273302.1 4864418 D 444450 CDS YP_002273303.1 209399839 6971747 4865533..4866579 1 NC_011353.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4866579 6971747 ECH74115_5218 Escherichia coli O157:H7 str. EC4115 lipopolysaccharide biosynthesis protein WzzE YP_002273303.1 4865533 D 444450 CDS YP_002273304.1 209399621 6970996 4866635..4867765 1 NC_011353.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 4867765 6970996 ECH74115_5219 Escherichia coli O157:H7 str. EC4115 UDP-N-acetylglucosamine 2-epimerase YP_002273304.1 4866635 D 444450 CDS YP_002273305.1 209398347 6970765 4867762..4869024 1 NC_011353.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4869024 wecC 6970765 wecC Escherichia coli O157:H7 str. EC4115 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002273305.1 4867762 D 444450 CDS YP_002273306.1 209399629 6969387 4869024..4870091 1 NC_011353.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 4870091 rfbB2 6969387 rfbB2 Escherichia coli O157:H7 str. EC4115 dTDP-glucose 4,6-dehydratase YP_002273306.1 4869024 D 444450 CDS YP_002273307.1 209400406 6970774 4870110..4870991 1 NC_011353.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 4870991 rfbA1 6970774 rfbA1 Escherichia coli O157:H7 str. EC4115 glucose-1-phosphate thymidylyltransferase YP_002273307.1 4870110 D 444450 CDS YP_002273308.1 209400127 6971607 4870969..4871643 1 NC_011353.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382; TDP-fucosamine acetyltransferase 4871643 wecD 6971607 wecD Escherichia coli O157:H7 str. EC4115 TDP-fucosamine acetyltransferase YP_002273308.1 4870969 D 444450 CDS YP_002273309.1 209400869 6971312 4871648..4872778 1 NC_011353.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4872778 wecE 6971312 wecE Escherichia coli O157:H7 str. EC4115 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002273309.1 4871648 D 444450 CDS YP_002273310.1 209395930 6972101 4872780..4874030 1 NC_011353.1 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 4874030 6972101 ECH74115_5225 Escherichia coli O157:H7 str. EC4115 polysaccharide biosynthesis protein YP_002273310.1 4872780 D 444450 CDS YP_002273311.1 209396700 6966797 4874027..4875106 1 NC_011353.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4875106 wecF 6966797 wecF Escherichia coli O157:H7 str. EC4115 4-alpha-L-fucosyltransferase YP_002273311.1 4874027 D 444450 CDS YP_002273312.1 209397845 6967624 4875103..4876455 1 NC_011353.1 enterobacterial common antigen polymerase; common antigen polymerase 4876455 wzyE 6967624 wzyE Escherichia coli O157:H7 str. EC4115 common antigen polymerase YP_002273312.1 4875103 D 444450 CDS YP_002273313.1 209398583 6968837 4876458..4877198 1 NC_011353.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosaminuronic acid transferase 4877198 6968837 ECH74115_5228 Escherichia coli O157:H7 str. EC4115 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002273313.1 4876458 D 444450 CDS YP_002273314.1 209398945 6969644 4877389..4878774 1 NC_011353.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4878774 6969644 ECH74115_5229 Escherichia coli O157:H7 str. EC4115 transporter YP_002273314.1 4877389 D 444450 CDS YP_002273315.1 209399680 6972341 4879686..4880921 1 NC_011353.1 identified by match to protein family HMM PF04055; arylsulfatase-activating protein AslB 4880921 aslB 6972341 aslB Escherichia coli O157:H7 str. EC4115 arylsulfatase-activating protein AslB YP_002273315.1 4879686 D 444450 CDS YP_002273316.1 209399246 6970829 complement(4881089..4882744) 1 NC_011353.1 identified by match to protein family HMM PF00884; arylsulfatase 4882744 aslA 6970829 aslA Escherichia coli O157:H7 str. EC4115 arylsulfatase YP_002273316.1 4881089 R 444450 CDS YP_002273317.1 209398548 6970358 complement(4882887..4883024) 1 NC_011353.1 identified by glimmer; hypothetical protein 4883024 6970358 ECH74115_5238 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273317.1 4882887 R 444450 CDS YP_002273318.1 209395966 6972287 complement(4883423..4884619) 1 NC_011353.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540; protoheme IX biogenesis protein 4884619 hemY 6972287 hemY Escherichia coli O157:H7 str. EC4115 protoheme IX biogenesis protein YP_002273318.1 4883423 R 444450 CDS YP_002273319.1 209398025 6966834 complement(4884622..4885839) 1 NC_011353.1 identified by match to protein family HMM PF04375; uroporphyrinogen III C-methyltransferase 4885839 6966834 ECH74115_5241 Escherichia coli O157:H7 str. EC4115 uroporphyrinogen III C-methyltransferase YP_002273319.1 4884622 R 444450 CDS YP_002273320.1 209400120 6969038 complement(4885861..4886601) 1 NC_011353.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4886601 hemD 6969038 hemD Escherichia coli O157:H7 str. EC4115 uroporphyrinogen-III synthase YP_002273320.1 4885861 R 444450 CDS YP_002273321.1 209396873 6971305 complement(4886598..4887554) 1 NC_011353.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4887554 hemC 6971305 hemC Escherichia coli O157:H7 str. EC4115 porphobilinogen deaminase YP_002273321.1 4886598 R 444450 CDS YP_002273322.1 209396473 6967809 4887926..4890472 1 NC_011353.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4890472 cyaA 6967809 cyaA Escherichia coli O157:H7 str. EC4115 adenylate cyclase YP_002273322.1 4887926 D 444450 CDS YP_002273323.1 209399949 6967384 complement(4890512..4890832) 1 NC_011353.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4890832 cyaY 6967384 cyaY Escherichia coli O157:H7 str. EC4115 frataxin-like protein YP_002273323.1 4890512 R 444450 CDS YP_002273324.1 209400519 6971117 4890947..4891108 1 NC_011353.1 hypothetical protein 4891108 6971117 ECH74115_5246 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273324.1 4890947 D 444450 CDS YP_002273325.1 209398527 6971726 4891295..4891498 1 NC_011353.1 lipoprotein 4891498 6971726 ECH74115_5247 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002273325.1 4891295 D 444450 CDS YP_002273326.1 209399378 6969586 4891535..4892359 1 NC_011353.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4892359 dapF 6969586 dapF Escherichia coli O157:H7 str. EC4115 diaminopimelate epimerase YP_002273326.1 4891535 D 444450 CDS YP_002273327.1 209398950 6970503 4892356..4893063 1 NC_011353.1 identified by match to protein family HMM PF04340; hypothetical protein 4893063 6970503 ECH74115_5249 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273327.1 4892356 D 444450 CDS YP_002273328.1 209397621 6970044 4893060..4893956 1 NC_011353.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4893956 xerC 6970044 xerC Escherichia coli O157:H7 str. EC4115 site-specific tyrosine recombinase XerC YP_002273328.1 4893060 D 444450 CDS YP_002273329.1 209399544 6968602 4893956..4894672 1 NC_011353.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4894672 6968602 ECH74115_5251 Escherichia coli O157:H7 str. EC4115 flavin mononucleotide phosphatase YP_002273329.1 4893956 D 444450 CDS YP_002273330.1 209396002 6970680 4894756..4896918 1 NC_011353.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4896918 uvrD 6970680 uvrD Escherichia coli O157:H7 str. EC4115 DNA-dependent helicase II YP_002273330.1 4894756 D 444450 CDS YP_002273331.1 209397758 6966874 complement(4896963..4897865) 1 NC_011353.1 identified by match to protein family HMM PF01887; hypothetical protein 4897865 6966874 ECH74115_5253 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273331.1 4896963 R 444450 CDS YP_002273332.1 209396407 6968745 complement(4897948..4898712) 1 NC_011353.1 hypothetical protein 4898712 6968745 ECH74115_5254 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273332.1 4897948 R 444450 CDS YP_002273333.1 209396831 6967314 4898725..4898838 1 NC_011353.1 identified by glimmer; hypothetical protein 4898838 6967314 ECH74115_5255 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273333.1 4898725 D 444450 CDS YP_002273334.1 209398943 6967764 4899082..4900032 1 NC_011353.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4900032 corA 6967764 corA Escherichia coli O157:H7 str. EC4115 magnesium/nickel/cobalt transporter CorA YP_002273334.1 4899082 D 444450 CDS YP_002273335.1 209400671 6970037 complement(4900074..4900496) 1 NC_011353.1 identified by match to protein family HMM PF06092; hypothetical protein 4900496 6970037 ECH74115_5257 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273335.1 4900074 R 444450 CDS YP_002273336.1 209395816 6971889 complement(4900562..4901410) 1 NC_011353.1 identified by match to protein family HMM TIGR03034; hypothetical protein 4901410 6971889 ECH74115_5258 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273336.1 4900562 R 444450 CDS YP_002273337.1 209396462 6966673 4901546..4901743 1 NC_011353.1 identified by glimmer; hypothetical protein 4901743 6966673 ECH74115_5259 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273337.1 4901546 D 444450 CDS YP_002273338.1 209397955 6967373 complement(4902716..4903603) 1 NC_011353.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; RarD protein 4903603 rarD 6967373 rarD Escherichia coli O157:H7 str. EC4115 RarD protein YP_002273338.1 4902716 R 444450 CDS YP_002273339.1 209398393 6968960 complement(4903655..4904122) 1 NC_011353.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 4904122 6968960 ECH74115_5261 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273339.1 4903655 R 444450 CDS YP_002273340.1 209399349 6969437 4904287..4905156 1 NC_011353.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4905156 pldA 6969437 pldA Escherichia coli O157:H7 str. EC4115 phospholipase A YP_002273340.1 4904287 D 444450 CDS YP_002273341.1 209400089 6970470 4905283..4907118 1 NC_011353.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4907118 recQ 6970470 recQ Escherichia coli O157:H7 str. EC4115 ATP-dependent DNA helicase RecQ YP_002273341.1 4905283 D 444450 CDS YP_002273342.1 209396889 6971270 4907188..4907802 1 NC_011353.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; threonine efflux system 4907802 rhtC 6971270 rhtC Escherichia coli O157:H7 str. EC4115 threonine efflux system YP_002273342.1 4907188 D 444450 CDS YP_002273343.1 209397127 6967826 complement(4907864..4908484) 1 NC_011353.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/homoserine lactone efflux protein 4908484 rhtB 6967826 rhtB Escherichia coli O157:H7 str. EC4115 homoserine/homoserine lactone efflux protein YP_002273343.1 4907864 R 444450 CDS YP_002273344.1 209398086 6968076 4908595..4909617 1 NC_011353.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4909617 pldB 6968076 pldB Escherichia coli O157:H7 str. EC4115 lysophospholipase L2 YP_002273344.1 4908595 D 444450 CDS YP_002273345.1 209398986 6969104 4909625..4910425 1 NC_011353.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4910425 6969104 ECH74115_5267 Escherichia coli O157:H7 str. EC4115 sugar phosphatase YP_002273345.1 4909625 D 444450 CDS YP_002273346.1 209399445 6970085 complement(4910507..4911262) 1 NC_011353.1 hypothetical protein 4911262 6970085 ECH74115_5268 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273346.1 4910507 R 444450 CDS YP_002273347.1 209399435 6970573 complement(4911288..4912241) 1 NC_011353.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator MetR 4912241 metR 6970573 metR Escherichia coli O157:H7 str. EC4115 transcriptional regulator MetR YP_002273347.1 4911288 R 444450 CDS YP_002273348.1 209397354 6970563 4912477..4914738 1 NC_011353.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4914738 metE 6970563 metE Escherichia coli O157:H7 str. EC4115 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_002273348.1 4912477 D 444450 CDS YP_002273349.1 209398246 6968321 complement(4914778..4915593) 1 NC_011353.1 identified by match to protein family HMM PF01738; dienelactone hydrolase family protein 4915593 6968321 ECH74115_5271 Escherichia coli O157:H7 str. EC4115 dienelactone hydrolase family protein YP_002273349.1 4914778 R 444450 CDS YP_002273350.1 209395815 6969278 4915855..4916616 1 NC_011353.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4916616 udp 6969278 udp Escherichia coli O157:H7 str. EC4115 uridine phosphorylase YP_002273350.1 4915855 D 444450 CDS YP_002273351.1 209399701 6966672 4916757..4918184 1 NC_011353.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4918184 rmuC 6966672 rmuC Escherichia coli O157:H7 str. EC4115 DNA recombination protein RmuC YP_002273351.1 4916757 D 444450 CDS YP_002273352.1 209400443 6970851 4918279..4919034 1 NC_011353.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4919034 ubiE 6970851 ubiE Escherichia coli O157:H7 str. EC4115 ubiquinone/menaquinone biosynthesis methyltransferase YP_002273352.1 4918279 D 444450 CDS YP_002273353.1 209400799 6971647 4919048..4919653 1 NC_011353.1 identified by match to protein family HMM PF02036; hypothetical protein 4919653 6971647 ECH74115_5275 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273353.1 4919048 D 444450 CDS YP_002273354.1 209399288 6972027 4919650..4921290 1 NC_011353.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4921290 ubiB 6972027 ubiB Escherichia coli O157:H7 str. EC4115 ubiquinone biosynthesis protein UbiB YP_002273354.1 4919650 D 444450 CDS YP_002273355.1 209398842 6970404 4921369..4921638 1 NC_011353.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4921638 tatA 6970404 tatA Escherichia coli O157:H7 str. EC4115 twin arginine translocase A YP_002273355.1 4921369 D 444450 CDS YP_002273356.1 209400771 6969926 4921642..4922157 1 NC_011353.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4922157 tatB 6969926 tatB Escherichia coli O157:H7 str. EC4115 sec-independent translocase YP_002273356.1 4921642 D 444450 CDS YP_002273357.1 209399791 6971996 4922160..4922936 1 NC_011353.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4922936 tatC 6971996 tatC Escherichia coli O157:H7 str. EC4115 twin-arginine protein translocation system subunit TatC YP_002273357.1 4922160 D 444450 CDS YP_002273358.1 209397688 6970948 4922966..4923760 1 NC_011353.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4923760 tatD 6970948 tatD Escherichia coli O157:H7 str. EC4115 DNase TatD YP_002273358.1 4922966 D 444450 CDS YP_002273359.1 209396563 6968671 complement(4923757..4924245) 1 NC_011353.1 identified by match to protein family HMM PF02357; match to protein family HMM TIGR01955; transcriptional activator RfaH 4924245 rfaH 6968671 rfaH Escherichia coli O157:H7 str. EC4115 transcriptional activator RfaH YP_002273359.1 4923757 R 444450 CDS YP_002273360.1 209397095 6967477 4924412..4925905 1 NC_011353.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4925905 ubiD 6967477 ubiD Escherichia coli O157:H7 str. EC4115 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002273360.1 4924412 D 444450 CDS YP_002273361.1 209397573 6968043 4925951..4926652 1 NC_011353.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4926652 fre 6968043 fre Escherichia coli O157:H7 str. EC4115 FMN reductase YP_002273361.1 4925951 D 444450 CDS YP_002273362.1 209398395 6968549 complement(4926844..4928007) 1 NC_011353.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4928007 fadA 6968549 fadA Escherichia coli O157:H7 str. EC4115 3-ketoacyl-CoA thiolase YP_002273362.1 4926844 R 444450 CDS YP_002273363.1 209399089 6969439 complement(4928017..4930206) 1 NC_011353.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4930206 fadB 6969439 fadB Escherichia coli O157:H7 str. EC4115 multifunctional fatty acid oxidation complex subunit alpha YP_002273363.1 4928017 R 444450 CDS YP_002273364.1 209398417 6970191 4930396..4931727 1 NC_011353.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4931727 pepQ 6970191 pepQ Escherichia coli O157:H7 str. EC4115 proline dipeptidase YP_002273364.1 4930396 D 444450 CDS YP_002273365.1 209400622 6969464 4931724..4932341 1 NC_011353.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 4932341 6969464 ECH74115_5287 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273365.1 4931724 D 444450 CDS YP_002273366.1 209397794 6971834 4932380..4933831 1 NC_011353.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; potassium transporter 4933831 trkH 6971834 trkH Escherichia coli O157:H7 str. EC4115 potassium transporter YP_002273366.1 4932380 D 444450 CDS YP_002273367.1 209397190 6968783 4933843..4934388 1 NC_011353.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4934388 hemG 6968783 hemG Escherichia coli O157:H7 str. EC4115 protoporphyrinogen oxidase YP_002273367.1 4933843 D 444450 CDS YP_002273368.1 209398405 6972281 complement(4939973..4940500) 1 NC_011353.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein MobB 4940500 mobB 6972281 mobB Escherichia coli O157:H7 str. EC4115 molybdopterin-guanine dinucleotide biosynthesis protein MobB YP_002273368.1 4939973 R 444450 CDS YP_002273369.1 209400652 6969451 complement(4940482..4941066) 1 NC_011353.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4941066 mobA 6969451 mobA Escherichia coli O157:H7 str. EC4115 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_002273369.1 4940482 R 444450 CDS YP_002273370.1 209399915 6971868 4941136..4941405 1 NC_011353.1 identified by match to protein family HMM PF06288; hypothetical protein 4941405 6971868 ECH74115_5298 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273370.1 4941136 D 444450 CDS YP_002273371.1 209396233 6971079 4941482..4942468 1 NC_011353.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4942468 6971079 ECH74115_5299 Escherichia coli O157:H7 str. EC4115 serine/threonine protein kinase YP_002273371.1 4941482 D 444450 CDS YP_002273372.1 209400816 6967123 4942485..4943111 1 NC_011353.1 identified by match to protein family HMM PF01323; protein disulfide isomerase I 4943111 dsbA 6967123 dsbA Escherichia coli O157:H7 str. EC4115 protein disulfide isomerase I YP_002273372.1 4942485 D 444450 CDS YP_002273373.1 209397000 6972044 4943136..4943276 1 NC_011353.1 identified by glimmer; hypothetical protein 4943276 6972044 ECH74115_5301 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273373.1 4943136 D 444450 CDS YP_002273374.1 209396984 6967942 4943266..4944696 1 NC_011353.1 identified by match to protein family HMM PF06097; hypothetical protein 4944696 6967942 ECH74115_5302 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273374.1 4943266 D 444450 CDS YP_002273375.1 209397334 6967925 complement(4944737..4945693) 1 NC_011353.1 identified by match to protein family HMM PF01553; acyltransferase 4945693 6967925 ECH74115_5303 Escherichia coli O157:H7 str. EC4115 acyltransferase YP_002273375.1 4944737 R 444450 CDS YP_002273376.1 209397876 6968299 4945581..4945733 1 NC_011353.1 identified by glimmer; hypothetical protein 4945733 6968299 ECH74115_5304 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273376.1 4945581 D 444450 CDS YP_002273377.1 209395756 6968872 complement(4945789..4945908) 1 NC_011353.1 identified by glimmer; hypothetical protein 4945908 6968872 ECH74115_5305 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273377.1 4945789 R 444450 CDS YP_002273378.1 209400301 6966611 4946033..4948819 1 NC_011353.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4948819 polA 6966611 polA Escherichia coli O157:H7 str. EC4115 DNA polymerase I YP_002273378.1 4946033 D 444450 CDS YP_002273379.1 209400868 6972316 complement(4949038..4949181) 1 NC_011353.1 identified by glimmer; hypothetical protein 4949181 6972316 ECH74115_5307 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273379.1 4949038 R 444450 CDS YP_002273380.1 209398819 6972099 complement(4949201..4949833) 1 NC_011353.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4949833 engB 6972099 engB Escherichia coli O157:H7 str. EC4115 ribosome biogenesis GTP-binding protein YsxC YP_002273380.1 4949201 R 444450 CDS YP_002273381.1 209399376 6972299 4950415..4950921 1 NC_011353.1 identified by match to protein family HMM PF04220; hypothetical protein 4950921 6972299 ECH74115_5311 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273381.1 4950415 D 444450 CDS YP_002273382.1 209397284 6970501 complement(4950995..4951111) 1 NC_011353.1 identified by glimmer; hypothetical protein 4951111 6970501 ECH74115_5312 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273382.1 4950995 R 444450 CDS YP_002273383.1 209396387 6968245 4951110..4952483 1 NC_011353.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4952483 hemN 6968245 hemN Escherichia coli O157:H7 str. EC4115 coproporphyrinogen III oxidase YP_002273383.1 4951110 D 444450 CDS YP_002273384.1 209399991 6967293 complement(4952895..4954313) 1 NC_011353.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4954313 glnG 6967293 glnG Escherichia coli O157:H7 str. EC4115 nitrogen regulation protein NR(I) YP_002273384.1 4952895 R 444450 CDS YP_002273385.1 209400767 6971163 complement(4954316..4955365) 1 NC_011353.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4955365 glnL 6971163 glnL Escherichia coli O157:H7 str. EC4115 nitrogen regulation protein NR(II) YP_002273385.1 4954316 R 444450 CDS YP_002273386.1 209400069 6971992 complement(4955539..4956948) 1 NC_011353.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4956948 glnA 6971992 glnA Escherichia coli O157:H7 str. EC4115 glutamine synthetase YP_002273386.1 4955539 R 444450 CDS YP_002273387.1 209398166 6971248 4957321..4959144 1 NC_011353.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein 4959144 typA 6971248 typA Escherichia coli O157:H7 str. EC4115 GTP-binding protein YP_002273387.1 4957321 D 444450 CDS YP_002273388.1 209397414 6969191 4959361..4960071 1 NC_011353.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4960071 6969191 ECH74115_5318 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002273388.1 4959361 D 444450 CDS YP_002273389.1 209396988 6968382 4960079..4961059 1 NC_011353.1 identified by match to protein family HMM PF01261; AP endonuclease, family 2 4961059 6968382 ECH74115_5319 Escherichia coli O157:H7 str. EC4115 AP endonuclease, family 2 YP_002273389.1 4960079 D 444450 CDS YP_002273390.1 209396239 6967929 4961161..4962426 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 4962426 6967929 ECH74115_5320 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002273390.1 4961161 D 444450 CDS YP_002273391.1 209400419 6967130 complement(4962517..4963209) 1 NC_011353.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L 4963209 ompL 6967130 ompL Escherichia coli O157:H7 str. EC4115 outer membrane porin L YP_002273391.1 4962517 R 444450 CDS YP_002273392.1 209399685 6971620 complement(4963276..4964679) 1 NC_011353.1 identified by match to protein family HMM TIGR00792; sugar (Glycoside-Pentoside-Hexuronide) transporter family protein 4964679 6971620 ECH74115_5322 Escherichia coli O157:H7 str. EC4115 sugar (Glycoside-Pentoside-Hexuronide) transporter family protein YP_002273392.1 4963276 R 444450 CDS YP_002273393.1 209399281 6970834 complement(4964719..4966104) 1 NC_011353.1 identified by match to protein family HMM TIGR00792; sugar transporter family protein 4966104 6970834 ECH74115_5323 Escherichia coli O157:H7 str. EC4115 sugar transporter family protein YP_002273393.1 4964719 R 444450 CDS YP_002273394.1 209398541 6970397 complement(4966150..4968186) 1 NC_011353.1 identified by match to protein family HMM PF01055; alpha-glucosidase 4968186 6970397 ECH74115_5324 Escherichia coli O157:H7 str. EC4115 alpha-glucosidase YP_002273394.1 4966150 R 444450 CDS YP_002273395.1 209396303 6969600 complement(4968294..4969169) 1 NC_011353.1 identified by match to protein family HMM PF01925; membrane protein 4969169 6969600 ECH74115_5325 Escherichia coli O157:H7 str. EC4115 membrane protein YP_002273395.1 4968294 R 444450 CDS YP_002273396.1 209396906 6967198 complement(4969230..4970132) 1 NC_011353.1 identified by match to protein family HMM PF01263; aldose-1-epimerase family protein 4970132 6967198 ECH74115_5326 Escherichia coli O157:H7 str. EC4115 aldose-1-epimerase family protein YP_002273396.1 4969230 R 444450 CDS YP_002273397.1 209400556 6967844 complement(4970199..4971440) 1 NC_011353.1 identified by match to protein family HMM PF07221; N-acylglucosamine 2-epimerase 4971440 6967844 ECH74115_5327 Escherichia coli O157:H7 str. EC4115 N-acylglucosamine 2-epimerase YP_002273397.1 4970199 R 444450 CDS YP_002273398.1 209398360 6971765 complement(4971456..4972334) 1 NC_011353.1 identified by match to protein family HMM PF01791; deoxyribose-phosphate aldolase 4972334 6971765 ECH74115_5328 Escherichia coli O157:H7 str. EC4115 deoxyribose-phosphate aldolase YP_002273398.1 4971456 R 444450 CDS YP_002273399.1 209399372 6969401 complement(4972358..4973254) 1 NC_011353.1 identified by match to protein family HMM PF03446; 3-hydroxyisobutyrate dehydrogenase 4973254 6969401 ECH74115_5329 Escherichia coli O157:H7 str. EC4115 3-hydroxyisobutyrate dehydrogenase YP_002273399.1 4972358 R 444450 CDS YP_002273400.1 209397229 6970497 4973422..4974318 1 NC_011353.1 identified by match to protein family HMM PF00294; kinase, PfkB family 4974318 6970497 ECH74115_5330 Escherichia coli O157:H7 str. EC4115 kinase, PfkB family YP_002273400.1 4973422 D 444450 CDS YP_002273401.1 209398202 6968187 4974328..4975137 1 NC_011353.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; transcriptional regulator, DeoR/GntR family 4975137 6968187 ECH74115_5331 Escherichia coli O157:H7 str. EC4115 transcriptional regulator, DeoR/GntR family YP_002273401.1 4974328 D 444450 CDS YP_002273402.1 209396062 6969230 4975236..4975835 1 NC_011353.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; phosphatase 4975835 yihX 6969230 yihX Escherichia coli O157:H7 str. EC4115 phosphatase YP_002273402.1 4975236 D 444450 CDS YP_002273403.1 209398243 6966939 4975829..4976701 1 NC_011353.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4976701 rbn 6966939 rbn Escherichia coli O157:H7 str. EC4115 ribonuclease BN YP_002273403.1 4975829 D 444450 CDS YP_002273404.1 209396162 6969275 4976698..4977135 1 NC_011353.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4977135 dtd 6969275 dtd Escherichia coli O157:H7 str. EC4115 D-tyrosyl-tRNA(Tyr) deacylase YP_002273404.1 4976698 D 444450 CDS YP_002273405.1 209398236 6967045 4977132..4978121 1 NC_011353.1 identified by match to protein family HMM PF00583; match to protein family HMM PF09500; match to protein family HMM TIGR02447; GNAT family acetyltransferase 4978121 6967045 ECH74115_5335 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002273405.1 4977132 D 444450 CDS YP_002273406.1 209396420 6967704 4981040..4981258 1 NC_011353.1 identified by match to protein family HMM PF01402; ribbon-helix-helix protein, copG family 4981258 6967704 ECH74115_5339 Escherichia coli O157:H7 str. EC4115 ribbon-helix-helix protein, copG family YP_002273406.1 4981040 D 444450 CDS YP_002273407.1 209395775 6967327 4981475..4981717 1 NC_011353.1 hypothetical protein 4981717 6967327 ECH74115_5340 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273407.1 4981475 D 444450 CDS YP_002273408.1 209400177 6966631 complement(4982047..4982976) 1 NC_011353.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4982976 fdhE 6966631 fdhE Escherichia coli O157:H7 str. EC4115 formate dehydrogenase accessory protein FdhE YP_002273408.1 4982047 R 444450 CDS YP_002273409.1 209399092 6971364 complement(4982973..4983608) 1 NC_011353.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4983608 fdoI 6971364 fdoI Escherichia coli O157:H7 str. EC4115 formate dehydrogenase-O subunit gamma YP_002273409.1 4982973 R 444450 CDS YP_002273410.1 209398803 6970194 complement(4983605..4984507) 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase-O, iron-sulfur subunit 4984507 fdoH 6970194 fdoH Escherichia coli O157:H7 str. EC4115 formate dehydrogenase-O, iron-sulfur subunit YP_002273410.1 4983605 R 444450 CDS YP_002273411.1 209398609 6971880 4987764..4988597 1 NC_011353.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4988597 fdhD 6971880 fdhD Escherichia coli O157:H7 str. EC4115 formate dehydrogenase accessory protein YP_002273411.1 4987764 D 444450 CDS YP_002273412.1 209399359 6969672 4988751..4989806 1 NC_011353.1 lipoprotein 4989806 6969672 ECH74115_5347 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002273412.1 4988751 D 444450 CDS YP_002273413.1 209397591 6970481 complement(4989856..4991604) 1 NC_011353.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein 4991604 6970481 ECH74115_5348 Escherichia coli O157:H7 str. EC4115 frv operon regulatory protein YP_002273413.1 4989856 R 444450 CDS YP_002273414.1 209396256 6968569 complement(4991604..4992674) 1 NC_011353.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX 4992674 6968569 ECH74115_5349 Escherichia coli O157:H7 str. EC4115 fructose-specific phosphotransferase system protein FrvX YP_002273414.1 4991604 R 444450 CDS YP_002273415.1 209396987 6967149 complement(4992664..4994109) 1 NC_011353.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427; PTS system transporter subunits IIBC 4994109 6967149 ECH74115_5350 Escherichia coli O157:H7 str. EC4115 PTS system transporter subunits IIBC YP_002273415.1 4992664 R 444450 CDS YP_002273416.1 209396615 6967928 complement(4994114..4994560) 1 NC_011353.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA 4994560 6967928 ECH74115_5351 Escherichia coli O157:H7 str. EC4115 fructose-like phosphotransferase system subunit EIIA YP_002273416.1 4994114 R 444450 CDS YP_002273417.1 209399683 6967534 4995038..4996432 1 NC_011353.1 glycoporin RafY 4996432 rafY2 6967534 rafY2 Escherichia coli O157:H7 str. EC4115 glycoporin RafY YP_002273417.1 4995038 D 444450 CDS YP_002273418.1 209400078 6970832 complement(4996473..4996787) 1 NC_011353.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625; L-rhamnose 1-epimerase 4996787 rhaU 6970832 rhaU Escherichia coli O157:H7 str. EC4115 L-rhamnose 1-epimerase YP_002273418.1 4996473 R 444450 CDS YP_002273419.1 209400790 6971257 complement(4996797..4997621) 1 NC_011353.1 identified by match to protein family HMM PF00596; match to protein family HMM TIGR02624; rhamnulose-1-phosphate aldolase 4997621 rhaD 6971257 rhaD Escherichia coli O157:H7 str. EC4115 rhamnulose-1-phosphate aldolase YP_002273419.1 4996797 R 444450 CDS YP_002273420.1 209395912 6972016 complement(4997796..4999055) 1 NC_011353.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4999055 rhaA 6972016 rhaA Escherichia coli O157:H7 str. EC4115 L-rhamnose isomerase YP_002273420.1 4997796 R 444450 CDS YP_002273421.1 209396044 6966779 complement(4999052..5000521) 1 NC_011353.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 5000521 rhaB 6966779 rhaB Escherichia coli O157:H7 str. EC4115 rhamnulokinase YP_002273421.1 4999052 R 444450 CDS YP_002273422.1 209397166 6966920 5000600..5000749 1 NC_011353.1 identified by glimmer; hypothetical protein 5000749 6966920 ECH74115_5357 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273422.1 5000600 D 444450 CDS YP_002273423.1 209397755 6968119 5000809..5001645 1 NC_011353.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 5001645 rhaS 6968119 rhaS Escherichia coli O157:H7 str. EC4115 transcriptional activator RhaS YP_002273423.1 5000809 D 444450 CDS YP_002273424.1 209396565 6968742 5001629..5002567 1 NC_011353.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 5002567 rhaR 6968742 rhaR Escherichia coli O157:H7 str. EC4115 transcriptional activator RhaR YP_002273424.1 5001629 D 444450 CDS YP_002273425.1 209400600 6971008 5003883..5004503 1 NC_011353.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 5004503 sodA 6971008 sodA Escherichia coli O157:H7 str. EC4115 superoxide dismutase YP_002273425.1 5003883 D 444450 CDS YP_002273426.1 209398469 6971811 complement(5004544..5004660) 1 NC_011353.1 hypothetical protein 5004660 6971811 ECH74115_5363 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273426.1 5004544 R 444450 CDS YP_002273427.1 209399566 6969523 5004763..5005746 1 NC_011353.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 5005746 kdgT 6969523 kdgT Escherichia coli O157:H7 str. EC4115 2-keto-3-deoxygluconate permease YP_002273427.1 5004763 D 444450 CDS YP_002273428.1 209400991 6970704 5005895..5006569 1 NC_011353.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475; hypothetical protein 5006569 6970704 ECH74115_5365 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273428.1 5005895 D 444450 CDS YP_002273429.1 209398760 6972233 complement(5006675..5008048) 1 NC_011353.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 5008048 cpxA 6972233 cpxA Escherichia coli O157:H7 str. EC4115 two-component sensor protein YP_002273429.1 5006675 R 444450 CDS YP_002273430.1 209397017 6969838 complement(5008045..5008743) 1 NC_011353.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 5008743 cpxR 6969838 cpxR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator CpxR YP_002273430.1 5008045 R 444450 CDS YP_002273431.1 209397775 6967961 5008893..5009393 1 NC_011353.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 5009393 cpxP 6967961 cpxP Escherichia coli O157:H7 str. EC4115 repressor CpxP YP_002273431.1 5008893 D 444450 CDS YP_002273432.1 209395908 6968763 5009542..5010444 1 NC_011353.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 5010444 fieF 6968763 fieF Escherichia coli O157:H7 str. EC4115 ferrous iron efflux protein F YP_002273432.1 5009542 D 444450 CDS YP_002273433.1 209396626 6966774 5010625..5011587 1 NC_011353.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 5011587 pfkA 6966774 pfkA Escherichia coli O157:H7 str. EC4115 6-phosphofructokinase YP_002273433.1 5010625 D 444450 CDS YP_002273434.1 209400083 6967546 complement(5011696..5011878) 1 NC_011353.1 hypothetical protein 5011878 6967546 ECH74115_5371 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273434.1 5011696 R 444450 CDS YP_002273435.1 209400686 6971262 5011906..5012895 1 NC_011353.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate transporter subunit 5012895 sbp 6971262 sbp Escherichia coli O157:H7 str. EC4115 sulfate transporter subunit YP_002273435.1 5011906 D 444450 CDS YP_002273436.1 209400064 6971906 5013002..5013757 1 NC_011353.1 identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672; CDP-diacylglycerol pyrophosphatase 5013757 cdh 6971906 cdh Escherichia coli O157:H7 str. EC4115 CDP-diacylglycerol pyrophosphatase YP_002273436.1 5013002 D 444450 CDS YP_002273437.1 209400689 6971243 complement(5013812..5014579) 1 NC_011353.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 5014579 tpiA 6971243 tpiA Escherichia coli O157:H7 str. EC4115 triosephosphate isomerase YP_002273437.1 5013812 R 444450 CDS YP_002273438.1 209398955 6971909 complement(5014687..5015286) 1 NC_011353.1 identified by match to protein family HMM PF07305; hypothetical protein 5015286 6971909 ECH74115_5375 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273438.1 5014687 R 444450 CDS YP_002273439.1 209399380 6970049 5015387..5015827 1 NC_011353.1 identified by match to protein family HMM PF05656; hypothetical protein 5015827 6970049 ECH74115_5376 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273439.1 5015387 D 444450 CDS YP_002273440.1 209396921 6970505 5016039..5016338 1 NC_011353.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein 5016338 6970505 ECH74115_5377 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273440.1 5016039 D 444450 CDS YP_002273441.1 209400015 6967859 5016365..5016793 1 NC_011353.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 5016793 uspD 6967859 uspD Escherichia coli O157:H7 str. EC4115 universal stress protein UspD YP_002273441.1 5016365 D 444450 CDS YP_002273442.1 209400937 6971190 complement(5016798..5017544) 1 NC_011353.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP reductase 5017544 fpr 6971190 fpr Escherichia coli O157:H7 str. EC4115 ferredoxin-NADP reductase YP_002273442.1 5016798 R 444450 CDS YP_002273443.1 209398845 6972174 complement(5017641..5018651) 1 NC_011353.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 5018651 glpX 6972174 glpX Escherichia coli O157:H7 str. EC4115 fructose 1,6-bisphosphatase II YP_002273443.1 5017641 R 444450 CDS YP_002273444.1 209397039 6969929 complement(5018881..5020389) 1 NC_011353.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 5020389 glpK 6969929 glpK Escherichia coli O157:H7 str. EC4115 glycerol kinase YP_002273444.1 5018881 R 444450 CDS YP_002273445.1 209397790 6967983 complement(5020412..5021257) 1 NC_011353.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 5021257 glpF 6967983 glpF Escherichia coli O157:H7 str. EC4115 glycerol uptake facilitator protein YP_002273445.1 5020412 R 444450 CDS YP_002273446.1 209395857 6968779 5021689..5021928 1 NC_011353.1 identified by match to protein family HMM PF06005; hypothetical protein 5021928 6968779 ECH74115_5383 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273446.1 5021689 D 444450 CDS YP_002273447.1 209396413 6966715 complement(5021967..5022374) 1 NC_011353.1 identified by glimmer; hypothetical protein 5022374 6966715 ECH74115_5384 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273447.1 5021967 R 444450 CDS YP_002273448.1 209396501 6967320 complement(5022716..5023390) 1 NC_011353.1 identified by glimmer; hypothetical protein 5023390 6967320 ECH74115_5385 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273448.1 5022716 R 444450 CDS YP_002273449.1 209397118 6967413 complement(5023450..5023935) 1 NC_011353.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 5023935 rraA 6967413 rraA Escherichia coli O157:H7 str. EC4115 ribonuclease activity regulator protein RraA YP_002273449.1 5023450 R 444450 CDS YP_002273450.1 209400732 6968067 complement(5024028..5024966) 1 NC_011353.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 5024966 menA 6968067 menA Escherichia coli O157:H7 str. EC4115 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002273450.1 5024028 R 444450 CDS YP_002273451.1 209395997 6971956 complement(5025021..5026352) 1 NC_011353.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 5026352 hslU 6971956 hslU Escherichia coli O157:H7 str. EC4115 ATP-dependent protease ATP-binding subunit HslU YP_002273451.1 5025021 R 444450 CDS YP_002273452.1 209399609 6966869 complement(5026362..5026892) 1 NC_011353.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 5026892 hslV 6966869 hslV Escherichia coli O157:H7 str. EC4115 ATP-dependent protease peptidase subunit YP_002273452.1 5026362 R 444450 CDS YP_002273453.1 209400145 6970753 complement(5026985..5027944) 1 NC_011353.1 identified by match to protein family HMM PF05036; match to protein family HMM TIGR02223; cell division protein FtsN 5027944 ftsN 6970753 ftsN Escherichia coli O157:H7 str. EC4115 cell division protein FtsN YP_002273453.1 5026985 R 444450 CDS YP_002273454.1 209397063 6971331 complement(5028036..5029028) 1 NC_011353.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 5029028 cytR 6971331 cytR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator CytR YP_002273454.1 5028036 R 444450 CDS YP_002273455.1 209398996 6968009 5029027..5029143 1 NC_011353.1 identified by glimmer; hypothetical protein 5029143 6968009 ECH74115_5392 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273455.1 5029027 D 444450 CDS YP_002273456.1 209398783 6970095 complement(5029217..5031415) 1 NC_011353.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 5031415 priA 6970095 priA Escherichia coli O157:H7 str. EC4115 primosome assembly protein PriA YP_002273456.1 5029217 R 444450 CDS YP_002273457.1 209399608 6969861 5031618..5031830 1 NC_011353.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 5031830 rpmE 6969861 rpmE Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L31 YP_002273457.1 5031618 D 444450 CDS YP_002273458.1 209395747 6970752 5031990..5036174 1 NC_011353.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RHS Repeat family protein 5036174 6970752 ECH74115_5395 Escherichia coli O157:H7 str. EC4115 RHS Repeat family protein YP_002273458.1 5031990 D 444450 CDS YP_002273459.1 209397441 6967790 complement(5037405..5038013) 1 NC_011353.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 5038013 6967790 ECH74115_5397 Escherichia coli O157:H7 str. EC4115 peptidoglycan peptidase YP_002273459.1 5037405 R 444450 CDS YP_002273460.1 209398026 6968411 complement(5038073..5038390) 1 NC_011353.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 5038390 metJ 6968411 metJ Escherichia coli O157:H7 str. EC4115 transcriptional repressor protein MetJ YP_002273460.1 5038073 R 444450 CDS YP_002273461.1 209398697 6969039 5038667..5039827 1 NC_011353.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 5039827 metB 6969039 metB Escherichia coli O157:H7 str. EC4115 cystathionine gamma-synthase YP_002273461.1 5038667 D 444450 CDS YP_002273462.1 209399480 6969769 5039830..5042262 1 NC_011353.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 5042262 metL 6969769 metL Escherichia coli O157:H7 str. EC4115 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_002273462.1 5039830 D 444450 CDS YP_002273463.1 209400229 6970613 complement(5042401..5042535) 1 NC_011353.1 identified by glimmer; hypothetical protein 5042535 6970613 ECH74115_5401 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273463.1 5042401 R 444450 CDS YP_002273464.1 209401006 6971419 5042611..5043501 1 NC_011353.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 5043501 metF 6971419 metF Escherichia coli O157:H7 str. EC4115 5,10-methylenetetrahydrofolate reductase YP_002273464.1 5042611 D 444450 CDS YP_002273465.1 209395777 6972248 5043830..5046010 1 NC_011353.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 5046010 katG 6972248 katG Escherichia coli O157:H7 str. EC4115 catalase/peroxidase HPI YP_002273465.1 5043830 D 444450 CDS YP_002273466.1 209396472 6966633 5046104..5047009 1 NC_011353.1 identified by match to protein family HMM PF00892; transporter 5047009 6966633 ECH74115_5404 Escherichia coli O157:H7 str. EC4115 transporter YP_002273466.1 5046104 D 444450 CDS YP_002273467.1 209396763 6967383 complement(5047036..5047653) 1 NC_011353.1 identified by match to protein family HMM PF06940; hypothetical protein 5047653 6967383 ECH74115_5405 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273467.1 5047036 R 444450 CDS YP_002273468.1 209396171 6967692 complement(5047927..5049030) 1 NC_011353.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 5049030 gldA 6967692 gldA Escherichia coli O157:H7 str. EC4115 glycerol dehydrogenase YP_002273468.1 5047927 R 444450 CDS YP_002273469.1 209400568 6967055 complement(5049041..5049703) 1 NC_011353.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 5049703 fsaB 6967055 fsaB Escherichia coli O157:H7 str. EC4115 fructose-6-phosphate aldolase YP_002273469.1 5049041 R 444450 CDS YP_002273470.1 209399874 6971778 complement(5049715..5052216) 1 NC_011353.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; multi-phosphoryl transfer protein 2 5052216 ptsA 6971778 ptsA Escherichia coli O157:H7 str. EC4115 multi-phosphoryl transfer protein 2 YP_002273470.1 5049715 R 444450 CDS YP_002273471.1 209398507 6971033 5052525..5053604 1 NC_011353.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 5053604 6971033 ECH74115_5409 Escherichia coli O157:H7 str. EC4115 fructose-like permease EIIC subunit 2 YP_002273471.1 5052525 D 444450 CDS YP_002273472.1 209400450 6969565 5053619..5053939 1 NC_011353.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit IIB 5053939 6969565 ECH74115_5410 Escherichia coli O157:H7 str. EC4115 PTS system fructose-like transporter subunit IIB YP_002273472.1 5053619 D 444450 CDS YP_002273473.1 209398325 6971655 5053990..5056287 1 NC_011353.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 5056287 pflD 6971655 pflD Escherichia coli O157:H7 str. EC4115 formate acetyltransferase 2 YP_002273473.1 5053990 D 444450 CDS YP_002273474.1 209397570 6969363 5056292..5057131 1 NC_011353.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate lyase II activase 5057131 6969363 ECH74115_5412 Escherichia coli O157:H7 str. EC4115 pyruvate formate lyase II activase YP_002273474.1 5056292 D 444450 CDS YP_002273475.1 209396067 6968546 5057133..5057474 1 NC_011353.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 5057474 6968546 ECH74115_5414 Escherichia coli O157:H7 str. EC4115 fructose-like phosphotransferase EIIB subunit 3 YP_002273475.1 5057133 D 444450 CDS YP_002273476.1 209400613 6966946 complement(5057461..5058312) 1 NC_011353.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 5058312 6966946 ECH74115_5413 Escherichia coli O157:H7 str. EC4115 AraC family transcriptional regulator YP_002273476.1 5057461 R 444450 CDS YP_002273477.1 209397001 6971825 complement(5058527..5060260) 1 NC_011353.1 identified by match to protein family HMM PF00884; hypothetical protein 5060260 6971825 ECH74115_5415 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273477.1 5058527 R 444450 CDS YP_002273478.1 209397772 6967943 complement(5060443..5063094) 1 NC_011353.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 5063094 ppc 6967943 ppc Escherichia coli O157:H7 str. EC4115 phosphoenolpyruvate carboxylase YP_002273478.1 5060443 R 444450 CDS YP_002273479.1 209398911 6968760 complement(5063446..5064597) 1 NC_011353.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 5064597 argE 6968760 argE Escherichia coli O157:H7 str. EC4115 acetylornithine deacetylase YP_002273479.1 5063446 R 444450 CDS YP_002273480.1 209399663 6970003 5064751..5065755 1 NC_011353.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 5065755 argC 6970003 argC Escherichia coli O157:H7 str. EC4115 N-acetyl-gamma-glutamyl-phosphate reductase YP_002273480.1 5064751 D 444450 CDS YP_002273481.1 209398952 6970810 5065766..5066539 1 NC_011353.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 5066539 argB 6970810 argB Escherichia coli O157:H7 str. EC4115 acetylglutamate kinase YP_002273481.1 5065766 D 444450 CDS YP_002273482.1 209399541 6970046 5066600..5067973 1 NC_011353.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 5067973 argH 6970046 argH Escherichia coli O157:H7 str. EC4115 argininosuccinate lyase YP_002273482.1 5066600 D 444450 CDS YP_002273483.1 209400897 6972315 5068240..5069157 1 NC_011353.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 5069157 oxyR 6972315 oxyR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator OxyR YP_002273483.1 5068240 D 444450 CDS YP_002273484.1 209400281 6972131 complement(5069140..5070540) 1 NC_011353.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 5070540 sthA 6972131 sthA Escherichia coli O157:H7 str. EC4115 soluble pyridine nucleotide transhydrogenase YP_002273484.1 5069140 R 444450 CDS YP_002273485.1 209397697 6971475 5070870..5072036 1 NC_011353.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; hippuricase 5072036 6971475 ECH74115_5424 Escherichia coli O157:H7 str. EC4115 hippuricase YP_002273485.1 5070870 D 444450 CDS YP_002273486.1 209396272 6968680 5072079..5073395 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator superfamily protein 5073395 6968680 ECH74115_5425 Escherichia coli O157:H7 str. EC4115 major facilitator superfamily protein YP_002273486.1 5072079 D 444450 CDS YP_002273487.1 209396287 6967165 5073445..5074149 1 NC_011353.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 5074149 fabR 6967165 fabR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor FabR YP_002273487.1 5073445 D 444450 CDS YP_002273488.1 209396895 6967181 5074149..5074508 1 NC_011353.1 identified by match to protein family HMM PF07226; hypothetical protein 5074508 6967181 ECH74115_5427 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273488.1 5074149 D 444450 CDS YP_002273489.1 209397508 6967833 complement(5074548..5075648) 1 NC_011353.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 5075648 trmA 6967833 trmA Escherichia coli O157:H7 str. EC4115 tRNA (uracil-5-)-methyltransferase YP_002273489.1 5074548 R 444450 CDS YP_002273490.1 209398063 6968480 5076017..5077861 1 NC_011353.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 5077861 btuB 6968480 btuB Escherichia coli O157:H7 str. EC4115 vitamin B12/cobalamin outer membrane transporter YP_002273490.1 5076017 D 444450 CDS YP_002273491.1 209400751 6969079 5077875..5078663 1 NC_011353.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 5078663 murI 6969079 murI Escherichia coli O157:H7 str. EC4115 glutamate racemase YP_002273491.1 5077875 D 444450 CDS YP_002273492.1 209396487 6972277 5084187..5085215 1 NC_011353.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 5085215 murB 6972277 murB Escherichia coli O157:H7 str. EC4115 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002273492.1 5084187 D 444450 CDS YP_002273493.1 209399876 6967399 5085212..5086177 1 NC_011353.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 5086177 birA 6967399 birA Escherichia coli O157:H7 str. EC4115 biotin--protein ligase YP_002273493.1 5085212 D 444450 CDS YP_002273494.1 209396990 6971035 complement(5086206..5087132) 1 NC_011353.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 5087132 coaA 6971035 coaA Escherichia coli O157:H7 str. EC4115 pantothenate kinase YP_002273494.1 5086206 R 444450 CDS YP_002273495.1 209397798 6967931 5087139..5087333 1 NC_011353.1 hypothetical protein 5087333 6967931 ECH74115_5440 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273495.1 5087139 D 444450 CDS YP_002273496.1 209400949 6972383 5088074..5089258 1 NC_011353.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 5089258 tuf1 6972383 tuf1 Escherichia coli O157:H7 str. EC4115 elongation factor Tu YP_002273496.1 5088074 D 444450 CDS YP_002273497.1 209396026 6972187 5089488..5089871 1 NC_011353.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 5089871 secE 6972187 secE Escherichia coli O157:H7 str. EC4115 preprotein translocase subunit SecE YP_002273497.1 5089488 D 444450 CDS YP_002273498.1 209399471 6966900 5089873..5090418 1 NC_011353.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 5090418 nusG 6966900 nusG Escherichia coli O157:H7 str. EC4115 transcription antitermination protein NusG YP_002273498.1 5089873 D 444450 CDS YP_002273499.1 209399885 6970603 5090577..5091005 1 NC_011353.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 5091005 rplK 6970603 rplK Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L11 YP_002273499.1 5090577 D 444450 CDS YP_002273500.1 209396827 6971047 5091009..5091713 1 NC_011353.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 5091713 rplA 6971047 rplA Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L1 YP_002273500.1 5091009 D 444450 CDS YP_002273501.1 209400268 6967760 5092005..5092502 1 NC_011353.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 5092502 rplJ 6967760 rplJ Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L10 YP_002273501.1 5092005 D 444450 CDS YP_002273502.1 209397838 6971461 5092569..5092934 1 NC_011353.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 5092934 rplL 6971461 rplL Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L7/L12 YP_002273502.1 5092569 D 444450 CDS YP_002273503.1 209395910 6972258 5093254..5097282 1 NC_011353.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 5097282 rpoB 6972258 rpoB Escherichia coli O157:H7 str. EC4115 DNA-directed RNA polymerase subunit beta YP_002273503.1 5093254 D 444450 CDS YP_002273504.1 209399168 6966776 5097359..5101582 1 NC_011353.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 5101582 rpoC 6966776 rpoC Escherichia coli O157:H7 str. EC4115 DNA-directed RNA polymerase subunit beta' YP_002273504.1 5097359 D 444450 CDS YP_002273505.1 209396336 6972325 complement(5102673..5103806) 1 NC_011353.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 5103806 thiH 6972325 thiH Escherichia coli O157:H7 str. EC4115 thiamine biosynthesis protein ThiH YP_002273505.1 5102673 R 444450 CDS YP_002273506.1 209396837 6967235 complement(5103803..5104618) 1 NC_011353.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 5104618 thiG 6967235 thiG Escherichia coli O157:H7 str. EC4115 thiazole synthase YP_002273506.1 5103803 R 444450 CDS YP_002273507.1 209397473 6967770 complement(5104575..5104775) 1 NC_011353.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 5104775 thiS 6967770 thiS Escherichia coli O157:H7 str. EC4115 sulfur carrier protein ThiS YP_002273507.1 5104575 R 444450 CDS YP_002273508.1 209398041 6968444 complement(5104759..5105514) 1 NC_011353.1 identified by match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356; thiazole biosynthesis adenylyltransferase ThiF 5105514 thiF 6968444 thiF Escherichia coli O157:H7 str. EC4115 thiazole biosynthesis adenylyltransferase ThiF YP_002273508.1 5104759 R 444450 CDS YP_002273509.1 209398607 6969054 complement(5105507..5106142) 1 NC_011353.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 5106142 thiE 6969054 thiE Escherichia coli O157:H7 str. EC4115 thiamine-phosphate pyrophosphorylase YP_002273509.1 5105507 R 444450 CDS YP_002273510.1 209399239 6969670 complement(5106142..5108037) 1 NC_011353.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 5108037 thiC 6969670 thiC Escherichia coli O157:H7 str. EC4115 thiamine biosynthesis protein ThiC YP_002273510.1 5106142 R 444450 CDS YP_002273511.1 209396887 6970350 complement(5108270..5108746) 1 NC_011353.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 5108746 rsd 6970350 rsd Escherichia coli O157:H7 str. EC4115 anti-RNA polymerase sigma 70 factor YP_002273511.1 5108270 R 444450 CDS YP_002273512.1 209400186 6967824 5108841..5109614 1 NC_011353.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 5109614 nudC 6967824 nudC Escherichia coli O157:H7 str. EC4115 NADH pyrophosphatase YP_002273512.1 5108841 D 444450 CDS YP_002273513.1 209398331 6971373 5109654..5110718 1 NC_011353.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 5110718 hemE 6971373 hemE Escherichia coli O157:H7 str. EC4115 uroporphyrinogen decarboxylase YP_002273513.1 5109654 D 444450 CDS YP_002273514.1 209396123 6969370 5110728..5111399 1 NC_011353.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 5111399 nfi 6969370 nfi Escherichia coli O157:H7 str. EC4115 endonuclease V YP_002273514.1 5110728 D 444450 CDS YP_002273515.1 209398075 6967003 5111442..5112032 1 NC_011353.1 identified by match to protein family HMM PF04222; hypothetical protein 5112032 6967003 ECH74115_5468 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273515.1 5111442 D 444450 CDS YP_002273516.1 209397488 6969092 5112219..5112491 1 NC_011353.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 5112491 hupA 6969092 hupA Escherichia coli O157:H7 str. EC4115 transcriptional regulator HU subunit alpha YP_002273516.1 5112219 D 444450 CDS YP_002273517.1 209396958 6968459 5112564..5113199 1 NC_011353.1 identified by match to protein family HMM PF07356; hypothetical protein 5113199 6968459 ECH74115_5470 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273517.1 5112564 D 444450 CDS YP_002273518.1 209395738 6967897 complement(5113201..5113626) 1 NC_011353.1 zinc resistance protein 5113626 zraP 6967897 zraP Escherichia coli O157:H7 str. EC4115 zinc resistance protein YP_002273518.1 5113201 R 444450 CDS YP_002273519.1 209398109 6966593 complement(5113629..5113757) 1 NC_011353.1 identified by glimmer; hypothetical protein 5113757 6966593 ECH74115_5472 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273519.1 5113629 R 444450 CDS YP_002273520.1 209397343 6969128 5113864..5115240 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein ZraS 5115240 zraS 6969128 zraS Escherichia coli O157:H7 str. EC4115 sensor protein ZraS YP_002273520.1 5113864 D 444450 CDS YP_002273521.1 209396243 6968310 5115237..5116562 1 NC_011353.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 5116562 zraR 6968310 zraR Escherichia coli O157:H7 str. EC4115 transcriptional regulatory protein ZraR YP_002273521.1 5115237 D 444450 CDS YP_002273522.1 209396846 6967135 complement(5116559..5117848) 1 NC_011353.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 5117848 purD 6967135 purD Escherichia coli O157:H7 str. EC4115 phosphoribosylamine--glycine ligase YP_002273522.1 5116559 R 444450 CDS YP_002273523.1 209398930 6967779 complement(5117860..5119449) 1 NC_011353.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5119449 purH 6967779 purH Escherichia coli O157:H7 str. EC4115 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002273523.1 5117860 R 444450 CDS YP_002273524.1 209396872 6972270 complement(5125193..5125636) 1 NC_011353.1 identified by match to protein family HMM PF00583; hypothetical protein 5125636 6972270 ECH74115_5482 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273524.1 5125193 R 444450 CDS YP_002273525.1 209400154 6967808 5125793..5126722 1 NC_011353.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 5126722 metA 6967808 metA Escherichia coli O157:H7 str. EC4115 homoserine O-succinyltransferase YP_002273525.1 5125793 D 444450 CDS YP_002273526.1 209400453 6971340 5126991..5128592 1 NC_011353.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 5128592 aceB 6971340 aceB Escherichia coli O157:H7 str. EC4115 malate synthase YP_002273526.1 5126991 D 444450 CDS YP_002273527.1 209398361 6971658 5128622..5129926 1 NC_011353.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346; isocitrate lyase 5129926 aceA 6971658 aceA Escherichia coli O157:H7 str. EC4115 isocitrate lyase YP_002273527.1 5128622 D 444450 CDS YP_002273528.1 209397504 6969403 5130110..5131846 1 NC_011353.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 5131846 aceK 6969403 aceK Escherichia coli O157:H7 str. EC4115 bifunctional isocitrate dehydrogenase kinase/phosphatase YP_002273528.1 5130110 D 444450 CDS YP_002273529.1 209399314 6968476 complement(5131815..5134001) 1 NC_011353.1 identified by match to protein family HMM PF07906; ShET2 enterotoxin, N- region family 5134001 6968476 ECH74115_5486 Escherichia coli O157:H7 str. EC4115 ShET2 enterotoxin, N- region family YP_002273529.1 5131815 R 444450 CDS YP_002273530.1 209397219 6970433 complement(5134318..5135142) 1 NC_011353.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 5135142 iclR 6970433 iclR Escherichia coli O157:H7 str. EC4115 IclR family transcriptional regulator YP_002273530.1 5134318 R 444450 CDS YP_002273531.1 209397983 6968177 5135342..5139025 1 NC_011353.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 5139025 metH 6968177 metH Escherichia coli O157:H7 str. EC4115 B12-dependent methionine synthase YP_002273531.1 5135342 D 444450 CDS YP_002273532.1 209398736 6968994 5139245..5140876 1 NC_011353.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013; inorganic phosphate transporter sodium-dependent 5140876 pNaS 6968994 pNaS Escherichia coli O157:H7 str. EC4115 inorganic phosphate transporter sodium-dependent YP_002273532.1 5139245 D 444450 CDS YP_002273533.1 209398575 6969811 complement(5140967..5141656) 1 NC_011353.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 5141656 pepE 6969811 pepE Escherichia coli O157:H7 str. EC4115 peptidase E YP_002273533.1 5140967 R 444450 CDS YP_002273534.1 209399290 6969636 5141927..5142070 1 NC_011353.1 identified by glimmer; hypothetical protein 5142070 6969636 ECH74115_5493 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273534.1 5141927 D 444450 CDS YP_002273535.1 209399864 6970406 complement(5142039..5143268) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-sorbose 1-phosphate reductase 5143268 6970406 ECH74115_5492 Escherichia coli O157:H7 str. EC4115 L-sorbose 1-phosphate reductase YP_002273535.1 5142039 R 444450 CDS YP_002273536.1 209398685 6971023 complement(5143320..5144144) 1 NC_011353.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system mannose/fructose/sorbose family transporter subunit IID 5144144 6971023 ECH74115_5494 Escherichia coli O157:H7 str. EC4115 PTS system mannose/fructose/sorbose family transporter subunit IID YP_002273536.1 5143320 R 444450 CDS YP_002273537.1 209398121 6969755 complement(5144155..5144952) 1 NC_011353.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822; PTS system mannose/fructose/sorbose family transporter subunit IIC 5144952 6969755 ECH74115_5495 Escherichia coli O157:H7 str. EC4115 PTS system mannose/fructose/sorbose family transporter subunit IIC YP_002273537.1 5144155 R 444450 CDS YP_002273538.1 209397359 6969122 complement(5145512..5145919) 1 NC_011353.1 identified by match to protein family HMM PF03610; match to protein family HMM TIGR00824; PTS system mannose/fructose/sorbose family transporter subunit IIA 5145919 6969122 ECH74115_5497 Escherichia coli O157:H7 str. EC4115 PTS system mannose/fructose/sorbose family transporter subunit IIA YP_002273538.1 5145512 R 444450 CDS YP_002273539.1 209395780 6968326 complement(5145929..5146735) 1 NC_011353.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 5146735 6968326 ECH74115_5498 Escherichia coli O157:H7 str. EC4115 sorbitol-6-phosphate 2-dehydrogenase YP_002273539.1 5145929 R 444450 CDS YP_002273540.1 209396331 6966636 complement(5146805..5147752) 1 NC_011353.1 identified by match to protein family HMM PF04198; sorbitol operon regulator SorC 5147752 sorC 6966636 sorC Escherichia coli O157:H7 str. EC4115 sorbitol operon regulator SorC YP_002273540.1 5146805 R 444450 CDS YP_002273541.1 209400390 6967228 5148100..5148972 1 NC_011353.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 5148972 rluF 6967228 rluF Escherichia coli O157:H7 str. EC4115 23S rRNA pseudouridine synthase F YP_002273541.1 5148100 D 444450 CDS YP_002273542.1 209399780 6971591 complement(5148973..5149245) 1 NC_011353.1 hypothetical protein 5149245 6971591 ECH74115_5501 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273542.1 5148973 R 444450 CDS YP_002273543.1 209399821 6970937 complement(5149498..5150847) 1 NC_011353.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 5150847 lysC 6970937 lysC Escherichia coli O157:H7 str. EC4115 aspartate kinase III YP_002273543.1 5149498 R 444450 CDS YP_002273544.1 209399227 6970978 5151372..5153021 1 NC_011353.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 5153021 pgi 6970978 pgi Escherichia coli O157:H7 str. EC4115 glucose-6-phosphate isomerase YP_002273544.1 5151372 D 444450 CDS YP_002273545.1 209396054 6970338 5153534..5153776 1 NC_011353.1 identified by glimmer; hypothetical protein 5153776 6970338 ECH74115_5505 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273545.1 5153534 D 444450 CDS YP_002273546.1 209400745 6966931 5153890..5154528 1 NC_011353.1 hypothetical protein 5154528 6966931 ECH74115_5506 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273546.1 5153890 D 444450 CDS YP_002273547.1 209397471 6971970 5154600..5155262 1 NC_011353.1 identified by match to protein family HMM PF06251; hypothetical protein 5155262 6971970 ECH74115_5507 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273547.1 5154600 D 444450 CDS YP_002273548.1 209396951 6968442 5155262..5157358 1 NC_011353.1 identified by match to protein family HMM PF06082; lipoprotein 5157358 6968442 ECH74115_5508 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002273548.1 5155262 D 444450 CDS YP_002273549.1 209399077 6967889 complement(5157405..5157683) 1 NC_011353.1 hypothetical protein 5157683 6967889 ECH74115_5509 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273549.1 5157405 R 444450 CDS YP_002273550.1 209398378 6970179 5157684..5157827 1 NC_011353.1 identified by glimmer; hypothetical protein 5157827 6970179 ECH74115_5510 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273550.1 5157684 D 444450 CDS YP_002273551.1 209399074 6969421 5157953..5158363 1 NC_011353.1 identified by match to protein family HMM PF06146; phosphate-starvation-inducible protein PsiE 5158363 psiE 6969421 psiE Escherichia coli O157:H7 str. EC4115 phosphate-starvation-inducible protein PsiE YP_002273551.1 5157953 D 444450 CDS YP_002273552.1 209398473 6970176 complement(5158407..5159882) 1 NC_011353.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 5159882 xylE 6970176 xylE Escherichia coli O157:H7 str. EC4115 D-xylose transporter XylE YP_002273552.1 5158407 R 444450 CDS YP_002273553.1 209398782 6969529 complement(5160254..5161144) 1 NC_011353.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 5161144 malG 6969529 malG Escherichia coli O157:H7 str. EC4115 maltose transporter permease YP_002273553.1 5160254 R 444450 CDS YP_002273554.1 209400802 6969860 complement(5161159..5162703) 1 NC_011353.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 5162703 malF 6969860 malF Escherichia coli O157:H7 str. EC4115 maltose transporter membrane protein YP_002273554.1 5161159 R 444450 CDS YP_002273555.1 209400060 6972030 complement(5162857..5164047) 1 NC_011353.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 5164047 malE 6972030 malE Escherichia coli O157:H7 str. EC4115 maltose ABC transporter periplasmic protein YP_002273555.1 5162857 R 444450 CDS YP_002273556.1 209399920 6971239 5164412..5165527 1 NC_011353.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 5165527 malK 6971239 malK Escherichia coli O157:H7 str. EC4115 maltose/maltodextrin transporter ATP-binding protein YP_002273556.1 5164412 D 444450 CDS YP_002273557.1 209396509 6971084 5165599..5166939 1 NC_011353.1 porin involved in the transport of maltose and maltodextrins; maltoporin 5166939 lamB 6971084 lamB Escherichia coli O157:H7 str. EC4115 maltoporin YP_002273557.1 5165599 D 444450 CDS YP_002273558.1 209396312 6967421 5167090..5168010 1 NC_011353.1 identified by match to protein family HMM PF07148; maltose regulon periplasmic protein 5168010 malM 6967421 malM Escherichia coli O157:H7 str. EC4115 maltose regulon periplasmic protein YP_002273558.1 5167090 D 444450 CDS YP_002273559.1 209398240 6967208 5168239..5169819 1 NC_011353.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 5169819 6967208 ECH74115_5519 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273559.1 5168239 D 444450 CDS YP_002273560.1 209397494 6969272 5170042..5170539 1 NC_011353.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 5170539 ubiC 6969272 ubiC Escherichia coli O157:H7 str. EC4115 chorismate pyruvate lyase YP_002273560.1 5170042 D 444450 CDS YP_002273561.1 209399362 6968466 5170552..5171424 1 NC_011353.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 5171424 ubiA 6968466 ubiA Escherichia coli O157:H7 str. EC4115 4-hydroxybenzoate octaprenyltransferase YP_002273561.1 5170552 D 444450 CDS YP_002273562.1 209399320 6970485 complement(5171579..5174002) 1 NC_011353.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 5174002 plsB 6970485 plsB Escherichia coli O157:H7 str. EC4115 glycerol-3-phosphate acyltransferase YP_002273562.1 5171579 R 444450 CDS YP_002273563.1 209396567 6970439 5174173..5174541 1 NC_011353.1 identified by match to protein family HMM PF01219; diacylglycerol kinase 5174541 dgkA 6970439 dgkA Escherichia coli O157:H7 str. EC4115 diacylglycerol kinase YP_002273563.1 5174173 D 444450 CDS YP_002273564.1 209400985 6967481 5174651..5175259 1 NC_011353.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 5175259 lexA 6967481 lexA Escherichia coli O157:H7 str. EC4115 LexA repressor YP_002273564.1 5174651 D 444450 CDS YP_002273565.1 209400391 6972227 5175332..5176657 1 NC_011353.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible SOS response protein 5176657 dinF 6972227 dinF Escherichia coli O157:H7 str. EC4115 DNA-damage-inducible SOS response protein YP_002273565.1 5175332 D 444450 CDS YP_002273566.1 209398011 6971592 5176773..5176982 1 NC_011353.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 5176982 6971592 ECH74115_5526 Escherichia coli O157:H7 str. EC4115 stress-response protein YP_002273566.1 5176773 D 444450 CDS YP_002273567.1 209398589 6969023 complement(5177024..5177539) 1 NC_011353.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 5177539 zur 6969023 zur Escherichia coli O157:H7 str. EC4115 zinc uptake transcriptional repressor YP_002273567.1 5177024 R 444450 CDS YP_002273568.1 209399512 6969650 5177851..5178807 1 NC_011353.1 hypothetical protein 5178807 6969650 ECH74115_5528 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273568.1 5177851 D 444450 CDS YP_002273569.1 209400087 6970647 5179169..5179291 1 NC_011353.1 TIM-barrel protein, YjbN family 5179291 6970647 ECH74115_5529 Escherichia coli O157:H7 str. EC4115 TIM-barrel protein, YjbN family YP_002273569.1 5179169 D 444450 CDS YP_002273570.1 209396375 6971267 5179417..5179953 1 NC_011353.1 hypothetical protein 5179953 6971267 ECH74115_5530 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273570.1 5179417 D 444450 CDS YP_002273571.1 209395802 6967280 5180150..5180323 1 NC_011353.1 hypothetical protein 5180323 6967280 ECH74115_5531 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273571.1 5180150 D 444450 CDS YP_002273572.1 209396515 6966658 complement(5180371..5180664) 1 NC_011353.1 hypothetical protein 5180664 6966658 ECH74115_5532 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273572.1 5180371 R 444450 CDS YP_002273573.1 209396528 6967427 complement(5180689..5180805) 1 NC_011353.1 endodeoxyribonuclease 5180805 6967427 ECH74115_5533 Escherichia coli O157:H7 str. EC4115 endodeoxyribonuclease YP_002273573.1 5180689 R 444450 CDS YP_002273574.1 209396941 6967441 complement(5180997..5181194) 1 NC_011353.1 hypothetical protein 5181194 6967441 ECH74115_5534 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273574.1 5180997 R 444450 CDS YP_002273575.1 209399365 6970375 complement(5181811..5182140) 1 NC_011353.1 Eae protein 5182140 6970375 ECH74115_5537 Escherichia coli O157:H7 str. EC4115 Eae protein YP_002273575.1 5181811 R 444450 CDS YP_002273576.1 209400400 6970489 complement(5182152..5182688) 1 NC_011353.1 hypothetical protein 5182688 6970489 ECH74115_5538 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273576.1 5182152 R 444450 CDS YP_002273577.1 209399843 6971601 complement(5182816..5183202) 1 NC_011353.1 hypothetical protein 5183202 6971601 ECH74115_5539 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273577.1 5182816 R 444450 CDS YP_002273578.1 209396425 6971000 5183289..5183942 1 NC_011353.1 fibronectin type III domain-containing protein 5183942 6971000 ECH74115_5540 Escherichia coli O157:H7 str. EC4115 fibronectin type III domain-containing protein YP_002273578.1 5183289 D 444450 CDS YP_002273579.1 209395694 6967332 5184010..5184609 1 NC_011353.1 identified by match to protein family HMM PF06316; Ail/Lom family protein 5184609 6967332 ECH74115_5541 Escherichia coli O157:H7 str. EC4115 Ail/Lom family protein YP_002273579.1 5184010 D 444450 CDS YP_002273580.1 209398079 6966548 complement(5184610..5184738) 1 NC_011353.1 hypothetical protein 5184738 6966548 ECH74115_5542 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273580.1 5184610 R 444450 CDS YP_002273581.1 209397260 6969096 complement(5184897..5185757) 1 NC_011353.1 hypothetical protein 5185757 6969096 ECH74115_5543 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273581.1 5184897 R 444450 CDS YP_002273582.1 209396505 6968218 5185709..5185987 1 NC_011353.1 identified by match to protein family HMM PF06820; tail fiber protein 5185987 6968218 ECH74115_5544 Escherichia coli O157:H7 str. EC4115 tail fiber protein YP_002273582.1 5185709 D 444450 CDS YP_002273583.1 209396836 6967417 5185989..5186258 1 NC_011353.1 identified by match to protein family HMM PF06820; prophage tail fiber C-terminus family protein 5186258 6967417 ECH74115_5545 Escherichia coli O157:H7 str. EC4115 prophage tail fiber C-terminus family protein YP_002273583.1 5185989 D 444450 CDS YP_002273584.1 209400919 6967769 5186370..5186942 1 NC_011353.1 identified by match to protein family HMM PF06416; non-LEE-encoded effector NleG 5186942 6967769 ECH74115_5546 Escherichia coli O157:H7 str. EC4115 non-LEE-encoded effector NleG YP_002273584.1 5186370 D 444450 CDS YP_002273585.1 209398975 6972155 5187243..5187644 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 5187644 6972155 ECH74115_5547 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273585.1 5187243 D 444450 CDS YP_002273586.1 209399399 6970074 5187726..5188367 1 NC_011353.1 identified by match to protein family HMM PF06416; hypothetical protein 5188367 6970074 ECH74115_5548 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273586.1 5187726 D 444450 CDS YP_002273587.1 209397237 6970525 complement(5188528..5188776) 1 NC_011353.1 identified by match to protein family HMM PF06183; hypothetical protein 5188776 6970525 ECH74115_5549 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273587.1 5188528 R 444450 CDS YP_002273588.1 209397184 6968195 complement(5188838..5189935) 1 NC_011353.1 identified by match to protein family HMM PF00589; phage integrase family protein 5189935 6968195 ECH74115_5550 Escherichia coli O157:H7 str. EC4115 phage integrase family protein YP_002273588.1 5188838 R 444450 CDS YP_002273589.1 209398005 6968138 5190024..5191061 1 NC_011353.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 5191061 dusA 6968138 dusA Escherichia coli O157:H7 str. EC4115 tRNA-dihydrouridine synthase A YP_002273589.1 5190024 D 444450 CDS YP_002273590.1 209395779 6969017 5191195..5191437 1 NC_011353.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 5191437 pspG 6969017 pspG Escherichia coli O157:H7 str. EC4115 phage shock protein G YP_002273590.1 5191195 D 444450 CDS YP_002273591.1 209399283 6966635 complement(5191603..5192586) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; quinone oxidoreductase 5192586 qor 6966635 qor Escherichia coli O157:H7 str. EC4115 quinone oxidoreductase YP_002273591.1 5191603 R 444450 CDS YP_002273592.1 209398031 6970399 5192669..5194084 1 NC_011353.1 unwinds double stranded DNA; replicative DNA helicase 5194084 dnaB 6970399 dnaB Escherichia coli O157:H7 str. EC4115 replicative DNA helicase YP_002273592.1 5192669 D 444450 CDS YP_002273593.1 209397944 6969044 5194137..5195216 1 NC_011353.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 5195216 alr 6969044 alr Escherichia coli O157:H7 str. EC4115 alanine racemase YP_002273593.1 5194137 D 444450 CDS YP_002273594.1 209395724 6968947 5195427..5196662 1 NC_011353.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 5196662 tyrB 6968947 tyrB Escherichia coli O157:H7 str. EC4115 aromatic amino acid aminotransferase YP_002273594.1 5195427 D 444450 CDS YP_002273595.1 209400146 6971641 5197761..5198474 1 NC_011353.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 5198474 aphA 6971641 aphA Escherichia coli O157:H7 str. EC4115 acid phosphatase/phosphotransferase YP_002273595.1 5197761 D 444450 CDS YP_002273596.1 209399571 6971332 5198585..5199001 1 NC_011353.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149; hypothetical protein 5199001 6971332 ECH74115_5559 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273596.1 5198585 D 444450 CDS YP_002273597.1 209399431 6970709 5199005..5199361 1 NC_011353.1 identified by match to protein family HMM PF04237; hypothetical protein 5199361 6970709 ECH74115_5560 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273597.1 5199005 D 444450 CDS YP_002273598.1 209398765 6970559 complement(5199396..5202218) 1 NC_011353.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 5202218 uvrA 6970559 uvrA Escherichia coli O157:H7 str. EC4115 excinuclease ABC subunit A YP_002273598.1 5199396 R 444450 CDS YP_002273599.1 209397137 6969843 5202473..5203009 1 NC_011353.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 5203009 ssb 6969843 ssb Escherichia coli O157:H7 str. EC4115 single-stranded DNA-binding protein YP_002273599.1 5202473 D 444450 CDS YP_002273600.1 209399303 6968088 complement(5203108..5203389) 1 NC_011353.1 hypothetical protein 5203389 6968088 ECH74115_5563 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273600.1 5203108 R 444450 CDS YP_002273601.1 209399666 6970420 5203818..5205404 1 NC_011353.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 5205404 6970420 ECH74115_5564 Escherichia coli O157:H7 str. EC4115 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein YP_002273601.1 5203818 D 444450 CDS YP_002273602.1 209398875 6970813 complement(5205407..5205730) 1 NC_011353.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 5205730 soxS 6970813 soxS Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator SoxS YP_002273602.1 5205407 R 444450 CDS YP_002273603.1 209397033 6969961 5205816..5206280 1 NC_011353.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950; redox-sensitive transcriptional activator SoxR 5206280 soxR 6969961 soxR Escherichia coli O157:H7 str. EC4115 redox-sensitive transcriptional activator SoxR YP_002273603.1 5205816 D 444450 CDS YP_002273604.1 209398197 6970265 5206826..5208175 1 NC_011353.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inorganic anion transporter sulfate permease (SulP) family 5208175 6970265 ECH74115_5568 Escherichia coli O157:H7 str. EC4115 inorganic anion transporter sulfate permease (SulP) family YP_002273604.1 5206826 D 444450 CDS YP_002273605.1 209397615 6969225 5208153..5208269 1 NC_011353.1 identified by glimmer; hypothetical protein 5208269 6969225 ECH74115_5569 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273605.1 5208153 D 444450 CDS YP_002273606.1 209400054 6968596 5208326..5209975 1 NC_011353.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831; Na+/H+ antiporter 5209975 6968596 ECH74115_5570 Escherichia coli O157:H7 str. EC4115 Na+/H+ antiporter YP_002273606.1 5208326 D 444450 CDS YP_002273607.1 209396870 6971233 complement(5210129..5211421) 1 NC_011353.1 identified by match to protein family HMM PF00805; hypothetical protein 5211421 6971233 ECH74115_5571 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273607.1 5210129 R 444450 CDS YP_002273608.1 209398553 6967805 complement(5211602..5213251) 1 NC_011353.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 5213251 actP 6967805 actP Escherichia coli O157:H7 str. EC4115 acetate permease YP_002273608.1 5211602 R 444450 CDS YP_002273609.1 209397412 6969613 complement(5213248..5213562) 1 NC_011353.1 identified by match to protein family HMM PF04341; hypothetical protein 5213562 6969613 ECH74115_5573 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273609.1 5213248 R 444450 CDS YP_002273610.1 209399894 6968380 complement(5213763..5215721) 1 NC_011353.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 5215721 acsA 6968380 acsA Escherichia coli O157:H7 str. EC4115 acetyl-CoA synthetase YP_002273610.1 5213763 R 444450 CDS YP_002273611.1 209399293 6971056 5216114..5217550 1 NC_011353.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 5217550 nrfA 6971056 nrfA Escherichia coli O157:H7 str. EC4115 cytochrome c552 YP_002273611.1 5216114 D 444450 CDS YP_002273612.1 209396905 6970409 5217595..5218161 1 NC_011353.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 5218161 nrfB 6970409 nrfB Escherichia coli O157:H7 str. EC4115 cytochrome c nitrite reductase pentaheme subunit YP_002273612.1 5217595 D 444450 CDS YP_002273613.1 209396255 6967843 5218158..5218829 1 NC_011353.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149; cytochrome c nitrite reductase, Fe-S protein 5218829 nrfC 6967843 nrfC Escherichia coli O157:H7 str. EC4115 cytochrome c nitrite reductase, Fe-S protein YP_002273613.1 5218158 D 444450 CDS YP_002273614.1 209398055 6967148 5218826..5219782 1 NC_011353.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148; nrfD protein 5219782 nrfD 6967148 nrfD Escherichia coli O157:H7 str. EC4115 nrfD protein YP_002273614.1 5218826 D 444450 CDS YP_002273615.1 209397457 6969070 5219841..5221520 1 NC_011353.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 5221520 nrfE 6969070 nrfE Escherichia coli O157:H7 str. EC4115 heme lyase subunit NrfE YP_002273615.1 5219841 D 444450 CDS YP_002273616.1 209398766 6968428 5221513..5221896 1 NC_011353.1 identified by match to protein family HMM PF03918; match to protein family HMM TIGR03147; formate-dependent nitrite reductase complex subunit NrfF 5221896 nrfF 6968428 nrfF Escherichia coli O157:H7 str. EC4115 formate-dependent nitrite reductase complex subunit NrfF YP_002273616.1 5221513 D 444450 CDS YP_002273617.1 209398536 6969844 5221893..5222489 1 NC_011353.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; formate-dependent nitrite reductase complex subunit NrfG 5222489 nrfG 6969844 nrfG Escherichia coli O157:H7 str. EC4115 formate-dependent nitrite reductase complex subunit NrfG YP_002273617.1 5221893 D 444450 CDS YP_002273618.1 209400399 6969595 complement(5222623..5222751) 1 NC_011353.1 identified by glimmer; hypothetical protein 5222751 6969595 ECH74115_5582 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273618.1 5222623 R 444450 CDS YP_002273619.1 209399923 6971600 5222831..5224144 1 NC_011353.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 5224144 gltP 6971600 gltP Escherichia coli O157:H7 str. EC4115 glutamate/aspartate:proton symporter YP_002273619.1 5222831 D 444450 CDS YP_002273620.1 209396005 6971087 complement(5224322..5225011) 1 NC_011353.1 identified by match to protein family HMM PF08238; Sel1 repeat protein 5225011 6971087 ECH74115_5584 Escherichia coli O157:H7 str. EC4115 Sel1 repeat protein YP_002273620.1 5224322 R 444450 CDS YP_002273621.1 209399819 6970334 complement(5227450..5228916) 1 NC_011353.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 5228916 6970334 ECH74115_5588 Escherichia coli O157:H7 str. EC4115 outer membrane efflux protein MdtP YP_002273621.1 5227450 R 444450 CDS YP_002273622.1 209399505 6970976 complement(5228913..5230964) 1 NC_011353.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 5230964 mdtO 6970976 mdtO Escherichia coli O157:H7 str. EC4115 multidrug efflux system protein MdtO YP_002273622.1 5228913 R 444450 CDS YP_002273623.1 209400246 6970640 complement(5230964..5231995) 1 NC_011353.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 5231995 mdtN 6970640 mdtN Escherichia coli O157:H7 str. EC4115 multidrug resistance protein MdtN YP_002273623.1 5230964 R 444450 CDS YP_002273624.1 209400980 6971437 complement(5232014..5232289) 1 NC_011353.1 hypothetical protein 5232289 6971437 ECH74115_5591 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273624.1 5232014 R 444450 CDS YP_002273625.1 209397725 6972222 complement(5232406..5232525) 1 NC_011353.1 identified by glimmer; hypothetical protein 5232525 6972222 ECH74115_5592 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273625.1 5232406 R 444450 CDS YP_002273626.1 209400388 6968710 complement(5232498..5234483) 1 NC_011353.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 5234483 6968710 ECH74115_5593 Escherichia coli O157:H7 str. EC4115 metallo-beta-lactamase family protein YP_002273626.1 5232498 R 444450 CDS YP_002273627.1 209395750 6971589 complement(5234615..5234740) 1 NC_011353.1 identified by glimmer; hypothetical protein 5234740 6971589 ECH74115_5594 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273627.1 5234615 R 444450 CDS YP_002273628.1 209395753 6966605 5234774..5235481 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; winged helix family two component transcriptional regulator 5235481 6966605 ECH74115_5596 Escherichia coli O157:H7 str. EC4115 winged helix family two component transcriptional regulator YP_002273628.1 5234774 D 444450 CDS YP_002273629.1 209396508 6966608 complement(5235478..5236479) 1 NC_011353.1 identified by match to protein family HMM PF00294; PfkB domain-containing protein 5236479 6966608 ECH74115_5595 Escherichia coli O157:H7 str. EC4115 PfkB domain-containing protein YP_002273629.1 5235478 R 444450 CDS YP_002273630.1 209396544 6967420 complement(5236476..5237336) 1 NC_011353.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; hypothetical protein 5237336 6967420 ECH74115_5597 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273630.1 5236476 R 444450 CDS YP_002273631.1 209397336 6967458 complement(5237351..5238034) 1 NC_011353.1 identified by match to protein family HMM PF07385; hypothetical protein 5238034 6967458 ECH74115_5598 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273631.1 5237351 R 444450 CDS YP_002273632.1 209397860 6968301 complement(5238089..5239012) 1 NC_011353.1 identified by match to protein family HMM PF00532; periplasmic binding protein/LacI transcriptional regulator 5239012 6968301 ECH74115_5599 Escherichia coli O157:H7 str. EC4115 periplasmic binding protein/LacI transcriptional regulator YP_002273632.1 5238089 R 444450 CDS YP_002273633.1 209400838 6968852 complement(5239049..5240023) 1 NC_011353.1 identified by match to protein family HMM PF02653; ribose transport system permease RbsC 5240023 6968852 ECH74115_5600 Escherichia coli O157:H7 str. EC4115 ribose transport system permease RbsC YP_002273633.1 5239049 R 444450 CDS YP_002273634.1 209398733 6972069 complement(5240020..5241540) 1 NC_011353.1 identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA 5241540 6972069 ECH74115_5601 Escherichia coli O157:H7 str. EC4115 ribose import ATP-binding protein RbsA YP_002273634.1 5240020 R 444450 CDS YP_002273635.1 209396346 6969807 5241539..5241652 1 NC_011353.1 identified by glimmer; hypothetical protein 5241652 6969807 ECH74115_5602 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273635.1 5241539 D 444450 CDS YP_002273636.1 209400726 6967248 5241654..5243924 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; hypothetical protein 5243924 6967248 ECH74115_5603 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273636.1 5241654 D 444450 CDS YP_002273637.1 209399538 6970016 complement(5244398..5245156) 1 NC_011353.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 5245156 phnP 6970016 phnP Escherichia coli O157:H7 str. EC4115 carbon-phosphorus lyase complex accessory protein YP_002273637.1 5244398 R 444450 CDS YP_002273638.1 209397188 6969148 complement(5245580..5246137) 1 NC_011353.1 identified by match to protein family HMM TIGR02322; ribose 1,5-bisphosphokinase 5246137 phnN 6969148 phnN Escherichia coli O157:H7 str. EC4115 ribose 1,5-bisphosphokinase YP_002273638.1 5245580 R 444450 CDS YP_002273639.1 209396880 6968144 complement(5246137..5247273) 1 NC_011353.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318; phosphonate metabolism protein PhnM 5247273 phnM 6968144 phnM Escherichia coli O157:H7 str. EC4115 phosphonate metabolism protein PhnM YP_002273639.1 5246137 R 444450 CDS YP_002273640.1 209396040 6967817 complement(5247270..5247950) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02324; phosphonate C-P lyase system protein PhnL 5247950 phnL 6967817 phnL Escherichia coli O157:H7 str. EC4115 phosphonate C-P lyase system protein PhnL YP_002273640.1 5247270 R 444450 CDS YP_002273641.1 209400505 6966916 complement(5248061..5248819) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323; phosphonate C-P lyase system protein PhnK 5248819 phnK 6966916 phnK Escherichia coli O157:H7 str. EC4115 phosphonate C-P lyase system protein PhnK YP_002273641.1 5248061 R 444450 CDS YP_002273642.1 209399888 6971710 complement(5248816..5249661) 1 NC_011353.1 identified by match to protein family HMM PF06007; phosphonate metabolism protein PhnJ 5249661 phnJ 6971710 phnJ Escherichia coli O157:H7 str. EC4115 phosphonate metabolism protein PhnJ YP_002273642.1 5248816 R 444450 CDS YP_002273643.1 209398848 6971050 complement(5249654..5250718) 1 NC_011353.1 identified by match to protein family HMM PF05861; phosphonate metabolism protein PhnI 5250718 phnI 6971050 phnI Escherichia coli O157:H7 str. EC4115 phosphonate metabolism protein PhnI YP_002273643.1 5249654 R 444450 CDS YP_002273644.1 209396310 6969933 complement(5250718..5251302) 1 NC_011353.1 identified by match to protein family HMM PF05845; match to protein family HMM TIGR03292; carbon-phosphorus lyase complex subunit 5251302 phnH 6969933 phnH Escherichia coli O157:H7 str. EC4115 carbon-phosphorus lyase complex subunit YP_002273644.1 5250718 R 444450 CDS YP_002273645.1 209400749 6967206 complement(5251299..5251751) 1 NC_011353.1 identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293; phosphonate C-P lyase system protein PhnG 5251751 phnG 6967206 phnG Escherichia coli O157:H7 str. EC4115 phosphonate C-P lyase system protein PhnG YP_002273645.1 5251299 R 444450 CDS YP_002273646.1 209397774 6971974 complement(5251752..5252477) 1 NC_011353.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 5252477 phnF 6971974 phnF Escherichia coli O157:H7 str. EC4115 phosphonate metabolism transcriptional regulator PhnF YP_002273646.1 5251752 R 444450 CDS YP_002273647.1 209397654 6968762 complement(5252498..5253277) 1 NC_011353.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097; phosphonate ABC transporter permease 5253277 phnE 6968762 phnE Escherichia coli O157:H7 str. EC4115 phosphonate ABC transporter permease YP_002273647.1 5252498 R 444450 CDS YP_002273648.1 209398344 6968637 5253272..5253421 1 NC_011353.1 identified by glimmer; hypothetical protein 5253421 6968637 ECH74115_5618 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273648.1 5253272 D 444450 CDS YP_002273649.1 209399090 6969384 complement(5253383..5254399) 1 NC_011353.1 identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431; phosphonate ABC transporter periplasmic phosphonate-binding protein 5254399 phnD 6969384 phnD Escherichia coli O157:H7 str. EC4115 phosphonate ABC transporter periplasmic phosphonate-binding protein YP_002273649.1 5253383 R 444450 CDS YP_002273650.1 209399487 6970192 complement(5254424..5255212) 1 NC_011353.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315; phosphonate/organophosphate ester transporter subunit 5255212 phnC 6970192 phnC Escherichia coli O157:H7 str. EC4115 phosphonate/organophosphate ester transporter subunit YP_002273650.1 5254424 R 444450 CDS YP_002273651.1 209399266 6970621 complement(5255345..5255788) 1 NC_011353.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983; hypothetical protein 5255788 6970621 ECH74115_5620 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273651.1 5255345 R 444450 CDS YP_002273652.1 209401005 6970382 complement(5256047..5256460) 1 NC_011353.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA 5256460 phnA 6970382 phnA Escherichia coli O157:H7 str. EC4115 alkylphosphonate utilization operon protein PhnA YP_002273652.1 5256047 R 444450 CDS YP_002273653.1 209400238 6972247 5256784..5259012 1 NC_011353.1 hypothetical protein 5259012 6972247 ECH74115_5622 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273653.1 5256784 D 444450 CDS YP_002273654.1 209398546 6971428 5259009..5259887 1 NC_011353.1 hypothetical protein 5259887 6971428 ECH74115_5623 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273654.1 5259009 D 444450 CDS YP_002273655.1 209400808 6969606 5260151..5261653 1 NC_011353.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883; proline/glycine betaine transporter 5261653 proP 6969606 proP Escherichia coli O157:H7 str. EC4115 proline/glycine betaine transporter YP_002273655.1 5260151 D 444450 CDS YP_002273656.1 209398018 6972036 complement(5261830..5262930) 1 NC_011353.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein BasS/PmrB 5262930 basS 6972036 basS Escherichia coli O157:H7 str. EC4115 sensor protein BasS/PmrB YP_002273656.1 5261830 R 444450 CDS YP_002273657.1 209397598 6969031 complement(5262931..5263599) 1 NC_011353.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 5263599 basR 6969031 basR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator BasR YP_002273657.1 5262931 R 444450 CDS YP_002273658.1 209396834 6968577 complement(5263596..5265239) 1 NC_011353.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 5265239 6968577 ECH74115_5627 Escherichia coli O157:H7 str. EC4115 cell division protein YP_002273658.1 5263596 R 444450 CDS YP_002273659.1 209396251 6967767 complement(5265343..5266680) 1 NC_011353.1 identified by match to protein family HMM PF00324; arginine:agmatin antiporter 5266680 adiC 6967767 adiC Escherichia coli O157:H7 str. EC4115 arginine:agmatin antiporter YP_002273659.1 5265343 R 444450 CDS YP_002273660.1 209396570 6967144 complement(5266817..5267578) 1 NC_011353.1 identified by match to protein family HMM PF00165; transcriptional regulator AdiY 5267578 adiY 6967144 adiY Escherichia coli O157:H7 str. EC4115 transcriptional regulator AdiY YP_002273660.1 5266817 R 444450 CDS YP_002273661.1 209395989 6967484 complement(5267535..5267672) 1 NC_011353.1 identified by glimmer; hypothetical protein 5267672 6967484 ECH74115_5630 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273661.1 5267535 R 444450 CDS YP_002273662.1 209400739 6966860 complement(5267903..5270173) 1 NC_011353.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; biodegradative arginine decarboxylase 5270173 adiA 6966860 adiA Escherichia coli O157:H7 str. EC4115 biodegradative arginine decarboxylase YP_002273662.1 5267903 R 444450 CDS YP_002273663.1 209400157 6971964 complement(5270369..5271277) 1 NC_011353.1 identified by match to protein family HMM PF00165; DNA-binding transcriptional regulator MelR 5271277 melR 6971964 melR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional regulator MelR YP_002273663.1 5270369 R 444450 CDS YP_002273664.1 209400354 6971343 5271560..5272915 1 NC_011353.1 identified by match to protein family HMM PF02056; alpha-galactosidase 5272915 melA 6971343 melA Escherichia coli O157:H7 str. EC4115 alpha-galactosidase YP_002273664.1 5271560 D 444450 CDS YP_002273665.1 209396194 6971552 5272994..5274439 1 NC_011353.1 identified by match to protein family HMM TIGR00792; melibiose:sodium symporter 5274439 melB 6971552 melB Escherichia coli O157:H7 str. EC4115 melibiose:sodium symporter YP_002273665.1 5272994 D 444450 CDS YP_002273666.1 209400315 6967081 complement(5274578..5275207) 1 NC_011353.1 hypothetical protein 5275207 6967081 ECH74115_5635 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273666.1 5274578 R 444450 CDS YP_002273667.1 209400759 6971511 complement(5275330..5276976) 1 NC_011353.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase 5276976 fumB 6971511 fumB Escherichia coli O157:H7 str. EC4115 fumarate hydratase YP_002273667.1 5275330 R 444450 CDS YP_002273668.1 209398687 6971984 complement(5277054..5278394) 1 NC_011353.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 5278394 dcuB 6971984 dcuB Escherichia coli O157:H7 str. EC4115 anaerobic C4-dicarboxylate transporter YP_002273668.1 5277054 R 444450 CDS YP_002273669.1 209398643 6969757 complement(5278965..5279684) 1 NC_011353.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 5279684 dcuR 6969757 dcuR Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator DcuR YP_002273669.1 5278965 R 444450 CDS YP_002273670.1 209397333 6969710 complement(5279681..5281312) 1 NC_011353.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 5281312 dcuS 6969710 dcuS Escherichia coli O157:H7 str. EC4115 sensory histidine kinase DcuS YP_002273670.1 5279681 R 444450 CDS YP_002273671.1 209397932 6968298 5281304..5281438 1 NC_011353.1 identified by glimmer; hypothetical protein 5281438 6968298 ECH74115_5640 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273671.1 5281304 D 444450 CDS YP_002273672.1 209395828 6968933 5281493..5281723 1 NC_011353.1 identified by match to protein family HMM PF06902; hypothetical protein 5281723 6968933 ECH74115_5641 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273672.1 5281493 D 444450 CDS YP_002273673.1 209396935 6966685 5281735..5282007 1 NC_011353.1 hypothetical protein 5282007 6966685 ECH74115_5642 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273673.1 5281735 D 444450 CDS YP_002273674.1 209399545 6967873 5282324..5282530 1 NC_011353.1 identified by glimmer; hypothetical protein 5282530 6967873 ECH74115_5643 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273674.1 5282324 D 444450 CDS YP_002273675.1 209399837 6970682 5282558..5282731 1 NC_011353.1 hypothetical protein 5282731 6970682 ECH74115_5644 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273675.1 5282558 D 444450 CDS YP_002273676.1 209400647 6970994 complement(5282850..5284367) 1 NC_011353.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 5284367 lysU 6970994 lysU Escherichia coli O157:H7 str. EC4115 lysyl-tRNA synthetase YP_002273676.1 5282850 R 444450 CDS YP_002273677.1 209398346 6971862 complement(5284604..5286061) 1 NC_011353.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 5286061 6971862 ECH74115_5646 Escherichia coli O157:H7 str. EC4115 amino acid/peptide transporter YP_002273677.1 5284604 R 444450 CDS YP_002273678.1 209399154 6969386 complement(5286120..5288267) 1 NC_011353.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase, constitutive 5288267 ldcC2 6969386 ldcC2 Escherichia coli O157:H7 str. EC4115 lysine decarboxylase, constitutive YP_002273678.1 5286120 R 444450 CDS YP_002273679.1 209397656 6970261 complement(5288347..5289681) 1 NC_011353.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 5289681 cadB 6970261 cadB Escherichia coli O157:H7 str. EC4115 lysine/cadaverine antiporter YP_002273679.1 5288347 R 444450 CDS YP_002273680.1 209398414 6968639 complement(5290047..5291585) 1 NC_011353.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 5291585 cadC 6968639 cadC Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator CadC YP_002273680.1 5290047 R 444450 CDS YP_002273681.1 209396131 6972424 complement(5292384..5292959) 1 NC_011353.1 identified by match to protein family HMM PF00440; transcriptional regulator 5292959 6972424 ECH74115_5651 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002273681.1 5292384 R 444450 CDS YP_002273682.1 209396839 6967013 complement(5292996..5294693) 1 NC_011353.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 5294693 dipZ 6967013 dipZ Escherichia coli O157:H7 str. EC4115 thiol:disulfide interchange protein YP_002273682.1 5292996 R 444450 CDS YP_002273683.1 209400734 6967772 complement(5294669..5295007) 1 NC_011353.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 5295007 cutA 6967772 cutA Escherichia coli O157:H7 str. EC4115 divalent-cation tolerance protein CutA YP_002273683.1 5294669 R 444450 CDS YP_002273684.1 209397673 6971959 complement(5295123..5296424) 1 NC_011353.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 5296424 dcuA 6971959 dcuA Escherichia coli O157:H7 str. EC4115 anaerobic C4-dicarboxylate transporter YP_002273684.1 5295123 R 444450 CDS YP_002273685.1 209399309 6968656 complement(5296542..5297978) 1 NC_011353.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 5297978 aspA 6968656 aspA Escherichia coli O157:H7 str. EC4115 aspartate ammonia-lyase YP_002273685.1 5296542 R 444450 CDS YP_002273686.1 209400815 6969605 complement(5298612..5300063) 1 NC_011353.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 5300063 6969605 ECH74115_5657 Escherichia coli O157:H7 str. EC4115 inner membrane protein YjeH YP_002273686.1 5298612 R 444450 CDS YP_002273687.1 209399891 6972043 5300339..5300632 1 NC_011353.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 5300632 groES 6972043 groES Escherichia coli O157:H7 str. EC4115 co-chaperonin GroES YP_002273687.1 5300339 D 444450 CDS YP_002273688.1 209398215 6971053 5300676..5302322 1 NC_011353.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 5302322 groEL 6971053 groEL Escherichia coli O157:H7 str. EC4115 chaperonin GroEL YP_002273688.1 5300676 D 444450 CDS YP_002273689.1 209397625 6969244 5302460..5302813 1 NC_011353.1 lipoprotein 5302813 6969244 ECH74115_5660 Escherichia coli O157:H7 str. EC4115 lipoprotein YP_002273689.1 5302460 D 444450 CDS YP_002273690.1 209396726 6968607 complement(5303006..5303875) 1 NC_011353.1 hypothetical protein 5303875 6968607 ECH74115_5661 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273690.1 5303006 R 444450 CDS YP_002273691.1 209396148 6967652 complement(5304110..5305138) 1 NC_011353.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238; KamA family protein 5305138 6967652 ECH74115_5662 Escherichia coli O157:H7 str. EC4115 KamA family protein YP_002273691.1 5304110 R 444450 CDS YP_002273692.1 209400534 6967031 5305180..5305746 1 NC_011353.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 5305746 efp 6967031 efp Escherichia coli O157:H7 str. EC4115 elongation factor P YP_002273692.1 5305180 D 444450 CDS YP_002273693.1 209398408 6971741 5305798..5305923 1 NC_011353.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 5305923 ecnB2 6971741 ecnB2 Escherichia coli O157:H7 str. EC4115 entericidin A YP_002273693.1 5305798 D 444450 CDS YP_002273694.1 209400363 6969454 5306034..5306180 1 NC_011353.1 identified by match to protein family HMM PF08085; entericidin B membrane lipoprotein 5306180 ecnB1 6969454 ecnB1 Escherichia coli O157:H7 str. EC4115 entericidin B membrane lipoprotein YP_002273694.1 5306034 D 444450 CDS YP_002273695.1 209396896 6971561 5306356..5306673 1 NC_011353.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 5306673 sugE 6971561 sugE Escherichia coli O157:H7 str. EC4115 quaternary ammonium compound-resistance protein SugE YP_002273695.1 5306356 D 444450 CDS YP_002273696.1 209399795 6967834 complement(5306670..5307203) 1 NC_011353.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 5307203 blc 6967834 blc Escherichia coli O157:H7 str. EC4115 outer membrane lipoprotein Blc YP_002273696.1 5306670 R 444450 CDS YP_002273697.1 209395845 6970952 complement(5307291..5308424) 1 NC_011353.1 identified by match to protein family HMM PF00144; beta-lactamase 5308424 ampC 6970952 ampC Escherichia coli O157:H7 str. EC4115 beta-lactamase YP_002273697.1 5307291 R 444450 CDS YP_002273698.1 209398193 6966702 complement(5308487..5308846) 1 NC_011353.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 5308846 frdD 6966702 frdD Escherichia coli O157:H7 str. EC4115 fumarate reductase subunit D YP_002273698.1 5308487 R 444450 CDS YP_002273699.1 209397602 6969221 complement(5308857..5309252) 1 NC_011353.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 5309252 frdC 6969221 frdC Escherichia coli O157:H7 str. EC4115 fumarate reductase subunit C YP_002273699.1 5308857 R 444450 CDS YP_002273700.1 209399718 6968582 complement(5309263..5309997) 1 NC_011353.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 5309997 frdB 6968582 frdB Escherichia coli O157:H7 str. EC4115 fumarate reductase iron-sulfur subunit YP_002273700.1 5309263 R 444450 CDS YP_002273701.1 209399135 6970870 complement(5309990..5311798) 1 NC_011353.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 5311798 frdA 6970870 frdA Escherichia coli O157:H7 str. EC4115 fumarate reductase flavoprotein subunit YP_002273701.1 5309990 R 444450 CDS YP_002273702.1 209395929 6970239 5312123..5313100 1 NC_011353.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 5313100 genX 6970239 genX Escherichia coli O157:H7 str. EC4115 lysyl-tRNA synthetase YP_002273702.1 5312123 D 444450 CDS YP_002273703.1 209396517 6966796 5313277..5314821 1 NC_011353.1 identified by match to protein family HMM PF00324; amino acid permease family protein 5314821 6966796 ECH74115_5674 Escherichia coli O157:H7 str. EC4115 amino acid permease family protein YP_002273703.1 5313277 D 444450 CDS YP_002273704.1 209400410 6967429 complement(5314972..5318295) 1 NC_011353.1 identified by match to protein family HMM PF00924; hypothetical protein 5318295 6967429 ECH74115_5675 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273704.1 5314972 R 444450 CDS YP_002273705.1 209399814 6971611 complement(5318317..5319285) 1 NC_011353.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 5319285 psd 6971611 psd Escherichia coli O157:H7 str. EC4115 phosphatidylserine decarboxylase YP_002273705.1 5318317 R 444450 CDS YP_002273706.1 209399218 6970971 complement(5319382..5320434) 1 NC_011353.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 5320434 rsgA 6970971 rsgA Escherichia coli O157:H7 str. EC4115 ribosome-associated GTPase YP_002273706.1 5319382 R 444450 CDS YP_002273707.1 209398620 6970328 5320529..5321074 1 NC_011353.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 5321074 orn 6970328 orn Escherichia coli O157:H7 str. EC4115 oligoribonuclease YP_002273707.1 5320529 D 444450 CDS YP_002273708.1 209396170 6972411 complement(5321853..5322992) 1 NC_011353.1 identified by match to protein family HMM PF08331; match to protein family HMM TIGR00276; iron-sulfur cluster binding protein 5322992 6972411 ECH74115_5682 Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster binding protein YP_002273708.1 5321853 R 444450 CDS YP_002273709.1 209398092 6967054 5323006..5324538 1 NC_011353.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; hypothetical protein 5324538 6967054 ECH74115_5683 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273709.1 5323006 D 444450 CDS YP_002273710.1 209400173 6969110 5324513..5324971 1 NC_011353.1 possibly involved in cell wall synthesis; ATPase 5324971 6969110 ECH74115_5684 Escherichia coli O157:H7 str. EC4115 ATPase YP_002273710.1 5324513 D 444450 CDS YP_002273711.1 209396446 6971360 5324990..5326327 1 NC_011353.1 identified by match to protein family HMM PF01520; N-acetylmuramoyl-l-alanine amidase II 5326327 amiB 6971360 amiB Escherichia coli O157:H7 str. EC4115 N-acetylmuramoyl-l-alanine amidase II YP_002273711.1 5324990 D 444450 CDS YP_002273712.1 209398397 6967356 5326337..5328184 1 NC_011353.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 5328184 mutL 6967356 mutL Escherichia coli O157:H7 str. EC4115 DNA mismatch repair protein YP_002273712.1 5326337 D 444450 CDS YP_002273713.1 209400590 6969441 5328177..5329127 1 NC_011353.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 5329127 miaA 6969441 miaA Escherichia coli O157:H7 str. EC4115 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002273713.1 5328177 D 444450 CDS YP_002273714.1 209400687 6971801 5329213..5329521 1 NC_011353.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 5329521 hfq 6971801 hfq Escherichia coli O157:H7 str. EC4115 RNA-binding protein Hfq YP_002273714.1 5329213 D 444450 CDS YP_002273715.1 209396581 6971907 5329598..5330878 1 NC_011353.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 5330878 hflX 6971907 hflX Escherichia coli O157:H7 str. EC4115 GTPase HflX YP_002273715.1 5329598 D 444450 CDS YP_002273716.1 209399796 6967496 5330964..5332223 1 NC_011353.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 5332223 hflK 6967496 hflK Escherichia coli O157:H7 str. EC4115 FtsH protease regulator HflK YP_002273716.1 5330964 D 444450 CDS YP_002273717.1 209397742 6970953 5332226..5333230 1 NC_011353.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 5333230 hflC 6970953 hflC Escherichia coli O157:H7 str. EC4115 FtsH protease regulator HflC YP_002273717.1 5332226 D 444450 CDS YP_002273718.1 209396294 6968727 5333312..5333509 1 NC_011353.1 hypothetical protein 5333509 6968727 ECH74115_5692 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273718.1 5333312 D 444450 CDS YP_002273719.1 209399548 6967189 5333613..5334911 1 NC_011353.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5334911 purA 6967189 purA Escherichia coli O157:H7 str. EC4115 adenylosuccinate synthetase YP_002273719.1 5333613 D 444450 CDS YP_002273720.1 209397401 6970685 5335116..5335541 1 NC_011353.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 5335541 nsrR 6970685 nsrR Escherichia coli O157:H7 str. EC4115 transcriptional repressor NsrR YP_002273720.1 5335116 D 444450 CDS YP_002273721.1 209398640 6968367 5335580..5338021 1 NC_011353.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 5338021 rnr 6968367 rnr Escherichia coli O157:H7 str. EC4115 exoribonuclease R YP_002273721.1 5335580 D 444450 CDS YP_002273722.1 209399233 6969706 5338202..5338933 1 NC_011353.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 5338933 6969706 ECH74115_5696 Escherichia coli O157:H7 str. EC4115 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002273722.1 5338202 D 444450 CDS YP_002273723.1 209397415 6970344 5339060..5339461 1 NC_011353.1 hypothetical protein 5339461 6970344 ECH74115_5697 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273723.1 5339060 D 444450 CDS YP_002273724.1 209398152 6968383 5339480..5340178 1 NC_011353.1 identified by match to protein family HMM PF04012; PspA/IM30 family protein 5340178 6968383 ECH74115_5698 Escherichia coli O157:H7 str. EC4115 PspA/IM30 family protein YP_002273724.1 5339480 D 444450 CDS YP_002273725.1 209398330 6969175 5340229..5340888 1 NC_011353.1 hypothetical protein 5340888 6969175 ECH74115_5699 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273725.1 5340229 D 444450 CDS YP_002273726.1 209396058 6969369 5340906..5341304 1 NC_011353.1 identified by match to protein family HMM PF03994; inner membrane protein 5341304 6969369 ECH74115_5700 Escherichia coli O157:H7 str. EC4115 inner membrane protein YP_002273726.1 5340906 D 444450 CDS YP_002273727.1 209396445 6966935 5341314..5341952 1 NC_011353.1 identified by match to protein family HMM PF06693; hypothetical protein 5341952 6966935 ECH74115_5701 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273727.1 5341314 D 444450 CDS YP_002273728.1 209400204 6967355 5341955..5343118 1 NC_011353.1 identified by match to protein family HMM PF03738; glutathionylspermidine synthase 5343118 6967355 ECH74115_5702 Escherichia coli O157:H7 str. EC4115 glutathionylspermidine synthase YP_002273728.1 5341955 D 444450 CDS YP_002273729.1 209399702 6971392 5343202..5344827 1 NC_011353.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 5344827 6971392 ECH74115_5703 Escherichia coli O157:H7 str. EC4115 isovaleryl CoA dehydrogenase YP_002273729.1 5343202 D 444450 CDS YP_002273730.1 209398768 6970852 complement(5344944..5345231) 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 5345231 6970852 ECH74115_5704 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273730.1 5344944 R 444450 CDS YP_002273731.1 209398392 6969846 complement(5345368..5345697) 1 NC_011353.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 5345697 6969846 ECH74115_5705 Escherichia coli O157:H7 str. EC4115 biofilm stress and motility protein A YP_002273731.1 5345368 R 444450 CDS YP_002273732.1 209398637 6969436 5345879..5346628 1 NC_011353.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 5346628 6969436 ECH74115_5707 Escherichia coli O157:H7 str. EC4115 esterase YP_002273732.1 5345879 D 444450 CDS YP_002273733.1 209399298 6969702 complement(5346625..5347380) 1 NC_011353.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 5347380 ulaR 6969702 ulaR Escherichia coli O157:H7 str. EC4115 transcriptional repressor UlaR YP_002273733.1 5346625 R 444450 CDS YP_002273734.1 209399245 6970414 complement(5347488..5348552) 1 NC_011353.1 L-ascorbate 6-phosphate lactonase 5348552 6970414 ECH74115_5708 Escherichia coli O157:H7 str. EC4115 L-ascorbate 6-phosphate lactonase YP_002273734.1 5347488 R 444450 CDS YP_002273735.1 209399248 6970357 5348907..5350304 1 NC_011353.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 5350304 ulaA 6970357 ulaA Escherichia coli O157:H7 str. EC4115 PTS system ascorbate-specific transporter subunit IIC YP_002273735.1 5348907 D 444450 CDS YP_002273736.1 209397475 6970362 5350320..5350625 1 NC_011353.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 5350625 ulaB 6970362 ulaB Escherichia coli O157:H7 str. EC4115 PTS system L-ascorbate-specific transporter subunit IIB YP_002273736.1 5350320 D 444450 CDS YP_002273737.1 209398074 6968446 5350635..5351099 1 NC_011353.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 5351099 ulaC 6968446 ulaC Escherichia coli O157:H7 str. EC4115 PTS system L-ascorbate-specific transporter subunit IIA YP_002273737.1 5350635 D 444450 CDS YP_002273738.1 209396289 6969091 5351113..5351763 1 NC_011353.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 5351763 ulaD 6969091 ulaD Escherichia coli O157:H7 str. EC4115 3-keto-L-gulonate-6-phosphate decarboxylase YP_002273738.1 5351113 D 444450 CDS YP_002273739.1 209396286 6967184 5351773..5352627 1 NC_011353.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 5352627 ulaE 6967184 ulaE Escherichia coli O157:H7 str. EC4115 L-xylulose 5-phosphate 3-epimerase YP_002273739.1 5351773 D 444450 CDS YP_002273740.1 209396852 6967180 5352627..5353313 1 NC_011353.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 5353313 sgaE 6967180 sgaE Escherichia coli O157:H7 str. EC4115 L-ribulose-5-phosphate 4-epimerase YP_002273740.1 5352627 D 444450 CDS YP_002273741.1 209400589 6967785 complement(5353442..5353717) 1 NC_011353.1 identified by match to protein family HMM PF07338; hypothetical protein 5353717 6967785 ECH74115_5715 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273741.1 5353442 R 444450 CDS YP_002273742.1 209398367 6971800 5354044..5354439 1 NC_011353.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 5354439 rpsF 6971800 rpsF Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S6 YP_002273742.1 5354044 D 444450 CDS YP_002273743.1 209400527 6969410 5354765..5354992 1 NC_011353.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5354992 rpsR 6969410 rpsR Escherichia coli O157:H7 str. EC4115 30S ribosomal protein S18 YP_002273743.1 5354765 D 444450 CDS YP_002273744.1 209400818 6971734 5355034..5355483 1 NC_011353.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 5355483 rplI 6971734 rplI Escherichia coli O157:H7 str. EC4115 50S ribosomal protein L9 YP_002273744.1 5355034 D 444450 CDS YP_002273745.1 209399021 6972046 complement(5355554..5356348) 1 NC_011353.1 hypothetical protein 5356348 6972046 ECH74115_5719 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273745.1 5355554 R 444450 CDS YP_002273746.1 209398645 6970121 5356791..5357117 1 NC_011353.1 hypothetical protein 5357117 6970121 ECH74115_5720 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273746.1 5356791 D 444450 CDS YP_002273747.1 209396231 6969712 5357286..5357432 1 NC_011353.1 identified by glimmer; hypothetical protein 5357432 6969712 ECH74115_5721 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273747.1 5357286 D 444450 CDS YP_002273748.1 209397707 6967121 5357410..5358618 1 NC_011353.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; transposase, IS605 orfB family 5358618 6967121 ECH74115_5722 Escherichia coli O157:H7 str. EC4115 transposase, IS605 orfB family YP_002273748.1 5357410 D 444450 CDS YP_002273749.1 209400063 6968691 complement(5358753..5359391) 1 NC_011353.1 identified by match to protein family HMM PF04225; match to protein family HMM PF08525; opacity-associated family protein 5359391 6968691 ECH74115_5723 Escherichia coli O157:H7 str. EC4115 opacity-associated family protein YP_002273749.1 5358753 R 444450 CDS YP_002273750.1 209396918 6971242 5359609..5360229 1 NC_011353.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 5360229 fklB 6971242 fklB Escherichia coli O157:H7 str. EC4115 peptidyl-prolyl cis-trans isomerase YP_002273750.1 5359609 D 444450 CDS YP_002273751.1 209399441 6967856 5360538..5361950 1 NC_011353.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 5361950 cycA 6967856 cycA Escherichia coli O157:H7 str. EC4115 D-alanine/D-serine/glycine permease YP_002273751.1 5360538 D 444450 CDS YP_002273752.1 209398714 6970569 complement(5361995..5362657) 1 NC_011353.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 5362657 6970569 ECH74115_5726 Escherichia coli O157:H7 str. EC4115 iron-sulfur cluster repair di-iron protein YP_002273752.1 5361995 R 444450 CDS YP_002273753.1 209399773 6969786 complement(5362765..5363730) 1 NC_011353.1 identified by match to protein family HMM PF00892; hypothetical protein 5363730 6969786 ECH74115_5727 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273753.1 5362765 R 444450 CDS YP_002273754.1 209400216 6970929 complement(5363838..5364698) 1 NC_011353.1 identified by match to protein family HMM PF01073; match to protein family HMM PF02254; match to protein family HMM PF05368; NmrA family protein 5364698 6970929 ECH74115_5728 Escherichia coli O157:H7 str. EC4115 NmrA family protein YP_002273754.1 5363838 R 444450 CDS YP_002273755.1 209398203 6971404 5364787..5365167 1 NC_011353.1 identified by match to protein family HMM PF01638; transcriptional regulator 5365167 6971404 ECH74115_5729 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002273755.1 5364787 D 444450 CDS YP_002273756.1 209396574 6969231 complement(5365285..5367228) 1 NC_011353.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 5367228 cpdB 6969231 cpdB Escherichia coli O157:H7 str. EC4115 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_002273756.1 5365285 R 444450 CDS YP_002273757.1 209397330 6967488 5367418..5368158 1 NC_011353.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 5368158 cysQ 6967488 cysQ Escherichia coli O157:H7 str. EC4115 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_002273757.1 5367418 D 444450 CDS YP_002273758.1 209397922 6968295 5368370..5369308 1 NC_011353.1 hypothetical protein 5369308 6968295 ECH74115_5732 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273758.1 5368370 D 444450 CDS YP_002273759.1 209398881 6968922 complement(5369371..5369925) 1 NC_011353.1 identified by match to protein family HMM PF09695; match to protein family HMM TIGR01626; hypothetical protein 5369925 6968922 ECH74115_5733 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273759.1 5369371 R 444450 CDS YP_002273760.1 209399477 6969970 5370250..5370456 1 NC_011353.1 identified by match to protein family HMM PF06526; hypothetical protein 5370456 6969970 ECH74115_5734 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273760.1 5370250 D 444450 CDS YP_002273761.1 209400045 6970610 complement(5370535..5371878) 1 NC_011353.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; transporter 5371878 6970610 ECH74115_5735 Escherichia coli O157:H7 str. EC4115 transporter YP_002273761.1 5370535 R 444450 CDS YP_002273762.1 209398598 6971222 complement(5372201..5372839) 1 NC_011353.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 5372839 msrA 6971222 msrA Escherichia coli O157:H7 str. EC4115 methionine sulfoxide reductase A YP_002273762.1 5372201 R 444450 CDS YP_002273763.1 209398724 6969660 5372947..5373075 1 NC_011353.1 identified by glimmer; hypothetical protein 5373075 6969660 ECH74115_5737 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273763.1 5372947 D 444450 CDS YP_002273764.1 209398307 6969797 5373045..5374778 1 NC_011353.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244; OMP85 family outer membrane protein 5374778 6969797 ECH74115_5738 Escherichia coli O157:H7 str. EC4115 OMP85 family outer membrane protein YP_002273764.1 5373045 D 444450 CDS YP_002273765.1 209399752 6969344 5374775..5378554 1 NC_011353.1 identified by match to protein family HMM PF04357; hypothetical protein 5378554 6969344 ECH74115_5739 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273765.1 5374775 D 444450 CDS YP_002273766.1 209399158 6970908 5378557..5378898 1 NC_011353.1 identified by match to protein family HMM PF06094; hypothetical protein 5378898 6970908 ECH74115_5740 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273766.1 5378557 D 444450 CDS YP_002273767.1 209400249 6970266 5379104..5379361 1 NC_011353.1 part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 5379361 chpS 6970266 chpS Escherichia coli O157:H7 str. EC4115 antitoxin ChpS YP_002273767.1 5379104 D 444450 CDS YP_002273768.1 209399815 6971440 5379355..5379705 1 NC_011353.1 toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 5379705 chpB 6971440 chpB Escherichia coli O157:H7 str. EC4115 toxin ChpB YP_002273768.1 5379355 D 444450 CDS YP_002273769.1 209396030 6970972 complement(5379785..5380315) 1 NC_011353.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 5380315 ppa 6970972 ppa Escherichia coli O157:H7 str. EC4115 inorganic pyrophosphatase YP_002273769.1 5379785 R 444450 CDS YP_002273770.1 209400962 6966906 5380314..5380454 1 NC_011353.1 identified by glimmer; hypothetical protein 5380454 6966906 ECH74115_5744 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273770.1 5380314 D 444450 CDS YP_002273771.1 209397917 6972200 5380625..5381581 1 NC_011353.1 identified by match to protein family HMM PF00532; sugar ABC transporter substrate-binding protein 5381581 6972200 ECH74115_5745 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter substrate-binding protein YP_002273771.1 5380625 D 444450 CDS YP_002273772.1 209400126 6968285 5383237..5384259 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF02653; sugar ABC transporter permease 5384259 6968285 ECH74115_5749 Escherichia coli O157:H7 str. EC4115 sugar ABC transporter permease YP_002273772.1 5383237 D 444450 CDS YP_002273773.1 209399118 6971311 5384246..5385241 1 NC_011353.1 membrane component of a sugar ABC transporter system; inner membrane ABC transporter permease YjfF 5385241 6971311 ECH74115_5750 Escherichia coli O157:H7 str. EC4115 inner membrane ABC transporter permease YjfF YP_002273773.1 5384246 D 444450 CDS YP_002273774.1 209395872 6970220 complement(5385274..5386272) 1 NC_011353.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 5386272 fbp 6970220 fbp Escherichia coli O157:H7 str. EC4115 fructose-1,6-bisphosphatase YP_002273774.1 5385274 R 444450 CDS YP_002273775.1 209400781 6966736 5386448..5387821 1 NC_011353.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 5387821 mpl 6966736 mpl Escherichia coli O157:H7 str. EC4115 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002273775.1 5386448 D 444450 CDS YP_002273776.1 209400523 6972006 complement(5387977..5388528) 1 NC_011353.1 identified by match to protein family HMM PF04751; hypothetical protein 5388528 yjgA 6972006 yjgA Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273776.1 5387977 R 444450 CDS YP_002273777.1 209396110 6971730 5388634..5389974 1 NC_011353.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 5389974 pmbA 6971730 pmbA Escherichia coli O157:H7 str. EC4115 peptidase PmbA YP_002273777.1 5388634 D 444450 CDS YP_002273778.1 209396412 6966990 5390158..5390544 1 NC_011353.1 identified by match to protein family HMM PF07361; soluble cytochrome b562 5390544 cybC 6966990 cybC Escherichia coli O157:H7 str. EC4115 soluble cytochrome b562 YP_002273778.1 5390158 D 444450 CDS YP_002273779.1 209397264 6967319 complement(5390589..5391053) 1 NC_011353.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 5391053 nrdG 6967319 nrdG Escherichia coli O157:H7 str. EC4115 anaerobic ribonucleotide reductase-activating protein YP_002273779.1 5390589 R 444450 CDS YP_002273780.1 209396188 6968222 5391042..5391236 1 NC_011353.1 hypothetical protein 5391236 6968222 ECH74115_5757 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273780.1 5391042 D 444450 CDS YP_002273781.1 209395826 6967075 complement(5391243..5393381) 1 NC_011353.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 5393381 nrdD 6967075 nrdD Escherichia coli O157:H7 str. EC4115 anaerobic ribonucleoside triphosphate reductase YP_002273781.1 5391243 R 444450 CDS YP_002273782.1 209400017 6966683 5393421..5393543 1 NC_011353.1 identified by glimmer; hypothetical protein 5393543 6966683 ECH74115_5759 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273782.1 5393421 D 444450 CDS YP_002273783.1 209399416 6971192 complement(5393627..5393803) 1 NC_011353.1 identified by glimmer; hypothetical protein 5393803 6971192 ECH74115_5760 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273783.1 5393627 R 444450 CDS YP_002273784.1 209400031 6970542 complement(5393775..5395430) 1 NC_011353.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; trehalose-6-phosphate hydrolase 5395430 treC 6970542 treC Escherichia coli O157:H7 str. EC4115 trehalose-6-phosphate hydrolase YP_002273784.1 5393775 R 444450 CDS YP_002273785.1 209399645 6971206 complement(5395480..5396901) 1 NC_011353.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 5396901 treB 6971206 treB Escherichia coli O157:H7 str. EC4115 PTS system trehalose(maltose)-specific transporter subunit IIBC YP_002273785.1 5395480 R 444450 CDS YP_002273786.1 209398866 6970790 complement(5397020..5397967) 1 NC_011353.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 5397967 treR 6970790 treR Escherichia coli O157:H7 str. EC4115 trehalose repressor YP_002273786.1 5397020 R 444450 CDS YP_002273787.1 209397808 6969952 5398346..5401042 1 NC_011353.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 5401042 mgtA 6969952 mgtA Escherichia coli O157:H7 str. EC4115 magnesium-transporting ATPase MgtA YP_002273787.1 5398346 D 444450 CDS YP_002273788.1 209397032 6968798 complement(5401248..5401673) 1 NC_011353.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP 5401673 6968798 ECH74115_5765 Escherichia coli O157:H7 str. EC4115 endoribonuclease L-PSP YP_002273788.1 5401248 R 444450 CDS YP_002273789.1 209396608 6967976 complement(5401707..5402168) 1 NC_011353.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 5402168 pyrI 6967976 pyrI Escherichia coli O157:H7 str. EC4115 aspartate carbamoyltransferase regulatory subunit YP_002273789.1 5401707 R 444450 CDS YP_002273790.1 209398491 6967526 complement(5402181..5403116) 1 NC_011353.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 5403116 pyrB 6967526 pyrB Escherichia coli O157:H7 str. EC4115 aspartate carbamoyltransferase catalytic subunit YP_002273790.1 5402181 R 444450 CDS YP_002273791.1 209397738 6969548 complement(5403293..5403430) 1 NC_011353.1 identified by glimmer; hypothetical protein 5403430 6969548 ECH74115_5768 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273791.1 5403293 R 444450 CDS YP_002273792.1 209397335 6968723 complement(5403535..5403930) 1 NC_011353.1 identified by match to protein family HMM PF01042; endoribonuclease L-PSP family protein 5403930 6968723 ECH74115_5769 Escherichia coli O157:H7 str. EC4115 endoribonuclease L-PSP family protein YP_002273792.1 5403535 R 444450 CDS YP_002273793.1 209396583 6968300 5403888..5404046 1 NC_011353.1 identified by glimmer; hypothetical protein 5404046 6968300 ECH74115_5770 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273793.1 5403888 D 444450 CDS YP_002273794.1 209400817 6967498 complement(5404061..5404774) 1 NC_011353.1 identified by match to protein family HMM PF00106; oxidoreductase 5404774 6967498 ECH74115_5771 Escherichia coli O157:H7 str. EC4115 oxidoreductase YP_002273794.1 5404061 R 444450 CDS YP_002273795.1 209400039 6972045 5404845..5405438 1 NC_011353.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5405438 6972045 ECH74115_5772 Escherichia coli O157:H7 str. EC4115 TetR family transcriptional regulator YP_002273795.1 5404845 D 444450 CDS YP_002273796.1 209399615 6971215 5405583..5406035 1 NC_011353.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 5406035 6971215 ECH74115_5773 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273796.1 5405583 D 444450 CDS YP_002273797.1 209398851 6970759 5406158..5407894 1 NC_011353.1 hypothetical protein 5407894 6970759 ECH74115_5774 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273797.1 5406158 D 444450 CDS YP_002273798.1 209398427 6969936 complement(5407951..5408955) 1 NC_011353.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 5408955 argF 6969936 argF Escherichia coli O157:H7 str. EC4115 ornithine carbamoyltransferase subunit I YP_002273798.1 5407951 R 444450 CDS YP_002273799.1 209398001 6969475 5409117..5409533 1 NC_011353.1 identified by match to protein family HMM PF06877; hypothetical protein 5409533 6969475 ECH74115_5776 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273799.1 5409117 D 444450 CDS YP_002273800.1 209396664 6969013 complement(5409579..5410082) 1 NC_011353.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 5410082 6969013 ECH74115_5777 Escherichia coli O157:H7 str. EC4115 GNAT family acetyltransferase YP_002273800.1 5409579 R 444450 CDS YP_002273801.1 209399763 6967585 5410248..5411471 1 NC_011353.1 identified by match to protein family HMM PF05987; hypothetical protein 5411471 6967585 ECH74115_5778 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273801.1 5410248 D 444450 CDS YP_002273802.1 209400172 6970919 complement(5411526..5414381) 1 NC_011353.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 5414381 valS 6970919 valS Escherichia coli O157:H7 str. EC4115 valyl-tRNA synthetase YP_002273802.1 5411526 R 444450 CDS YP_002273803.1 209400926 6971359 complement(5414381..5414824) 1 NC_011353.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 5414824 holC 6971359 holC Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit chi YP_002273803.1 5414381 R 444450 CDS YP_002273804.1 209397461 6972163 complement(5415178..5416689) 1 NC_011353.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 5416689 pepA 6972163 pepA Escherichia coli O157:H7 str. EC4115 leucyl aminopeptidase YP_002273804.1 5415178 R 444450 CDS YP_002273805.1 209398132 6968432 complement(5416914..5417042) 1 NC_011353.1 identified by glimmer; hypothetical protein 5417042 6968432 ECH74115_5782 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273805.1 5416914 R 444450 CDS YP_002273806.1 209395855 6969154 5416956..5418056 1 NC_011353.1 identified by match to protein family HMM PF03739; permease 5418056 6969154 ECH74115_5783 Escherichia coli O157:H7 str. EC4115 permease YP_002273806.1 5416956 D 444450 CDS YP_002273807.1 209396919 6966713 5418056..5419138 1 NC_011353.1 identified by match to protein family HMM PF03739; permease 5419138 6966713 ECH74115_5784 Escherichia coli O157:H7 str. EC4115 permease YP_002273807.1 5418056 D 444450 CDS YP_002273808.1 209399989 6967857 complement(5419299..5420801) 1 NC_011353.1 identified by match to protein family HMM PF05872; hypothetical protein 5420801 6967857 ECH74115_5785 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273808.1 5419299 R 444450 CDS YP_002273809.1 209400376 6971161 complement(5420931..5421950) 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 5421950 6971161 ECH74115_5786 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002273809.1 5420931 R 444450 CDS YP_002273810.1 209396718 6971576 complement(5422025..5422228) 1 NC_011353.1 hypothetical protein 5422228 6971576 ECH74115_5787 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273810.1 5422025 R 444450 CDS YP_002273811.1 209400288 6972350 5422570..5424240 1 NC_011353.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase family 5424240 6972350 ECH74115_5789 Escherichia coli O157:H7 str. EC4115 site-specific recombinase, phage integrase family YP_002273811.1 5422570 D 444450 CDS YP_002273812.1 209399919 6971482 complement(5424866..5425198) 1 NC_011353.1 identified by match to protein family HMM PF07978; nipsnap family protein 5425198 6971482 ECH74115_5790 Escherichia coli O157:H7 str. EC4115 nipsnap family protein YP_002273812.1 5424866 R 444450 CDS YP_002273813.1 209398818 6971083 complement(5426202..5426669) 1 NC_011353.1 identified by match to protein family HMM PF07799; hypothetical protein 5426669 6971083 ECH74115_5791 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273813.1 5426202 R 444450 CDS YP_002273814.1 209398462 6969900 5426793..5427431 1 NC_011353.1 identified by match to protein family HMM PF00239; resolvase TnpR 5427431 6969900 ECH74115_5792 Escherichia coli O157:H7 str. EC4115 resolvase TnpR YP_002273814.1 5426793 D 444450 CDS YP_002273815.1 209399018 6969515 complement(5427630..5428946) 1 NC_011353.1 hypothetical protein 5428946 6969515 ECH74115_5793 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273815.1 5427630 R 444450 CDS YP_002273816.1 209395914 6970118 complement(5429098..5429871) 1 NC_011353.1 hypothetical protein 5429871 6970118 ECH74115_5794 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273816.1 5429098 R 444450 CDS YP_002273817.1 209396646 6966781 5429988..5430452 1 NC_011353.1 identified by match to protein family HMM PF01381; transcriptional regulator 5430452 6966781 ECH74115_5795 Escherichia coli O157:H7 str. EC4115 transcriptional regulator YP_002273817.1 5429988 D 444450 CDS YP_002273818.1 209399960 6967566 5430608..5430721 1 NC_011353.1 identified by glimmer; hypothetical protein 5430721 6967566 ECH74115_5796 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273818.1 5430608 D 444450 CDS YP_002273819.1 209400524 6971130 5431168..5431995 1 NC_011353.1 prophage P4 integrase 5431995 6971130 ECH74115_5797 Escherichia coli O157:H7 str. EC4115 prophage P4 integrase YP_002273819.1 5431168 D 444450 CDS YP_002273820.1 209400044 6971837 complement(5432455..5433306) 1 NC_011353.1 HNH nuclease 5433306 6971837 ECH74115_5799 Escherichia coli O157:H7 str. EC4115 HNH nuclease YP_002273820.1 5432455 R 444450 CDS YP_002273821.1 209395990 6967343 complement(5433847..5434950) 1 NC_011353.1 hypothetical protein 5434950 6967343 ECH74115_5801 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273821.1 5433847 R 444450 CDS YP_002273822.1 209396899 6966861 complement(5434954..5435661) 1 NC_011353.1 hypothetical protein 5435661 6966861 ECH74115_5802 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273822.1 5434954 R 444450 CDS YP_002273823.1 209396327 6967837 complement(5435668..5437320) 1 NC_011353.1 hypothetical protein 5437320 6967837 ECH74115_5803 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273823.1 5435668 R 444450 CDS YP_002273824.1 209398030 6967224 complement(5437584..5437703) 1 NC_011353.1 identified by glimmer; hypothetical protein 5437703 6967224 ECH74115_5804 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273824.1 5437584 R 444450 CDS YP_002273825.1 209397351 6969043 5437955..5440891 1 NC_011353.1 identified by glimmer; hypothetical protein 5440891 6969043 ECH74115_5805 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273825.1 5437955 D 444450 CDS YP_002273826.1 209400597 6968318 5440891..5447205 1 NC_011353.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369; DEAD/DEAH box helicase 5447205 6968318 ECH74115_5807 Escherichia coli O157:H7 str. EC4115 DEAD/DEAH box helicase YP_002273826.1 5440891 D 444450 CDS YP_002273827.1 209398759 6971808 complement(5447192..5447308) 1 NC_011353.1 identified by glimmer; hypothetical protein 5447308 6971808 ECH74115_5806 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273827.1 5447192 R 444450 CDS YP_002273828.1 209398792 6969836 5447429..5450287 1 NC_011353.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; helicase family protein 5450287 6969836 ECH74115_5808 Escherichia coli O157:H7 str. EC4115 helicase family protein YP_002273828.1 5447429 D 444450 CDS YP_002273829.1 209400195 6969870 5450290..5455224 1 NC_011353.1 identified by glimmer; hypothetical protein 5455224 6969870 ECH74115_5809 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273829.1 5450290 D 444450 CDS YP_002273830.1 209399692 6971382 5455224..5461565 1 NC_011353.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369; DEAD/DEAH box helicase 5461565 6971382 ECH74115_5810 Escherichia coli O157:H7 str. EC4115 DEAD/DEAH box helicase YP_002273830.1 5455224 D 444450 CDS YP_002273831.1 209400456 6970842 5461562..5463676 1 NC_011353.1 identified by match to protein family HMM PF00580; ATP-dependent DNA helicase, UvrD/REP family 5463676 6970842 ECH74115_5811 Escherichia coli O157:H7 str. EC4115 ATP-dependent DNA helicase, UvrD/REP family YP_002273831.1 5461562 D 444450 CDS YP_002273832.1 209397227 6966721 complement(5465170..5466150) 1 NC_011353.1 identified by match to protein family HMM PF03629; hypothetical protein 5466150 6966721 ECH74115_5813 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273832.1 5465170 R 444450 CDS YP_002273833.1 209397986 6968185 complement(5466215..5467321) 1 NC_011353.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646; match to protein family HMM TIGR03547; N-acetylneuraminic acid mutarotase 5467321 6968185 ECH74115_5814 Escherichia coli O157:H7 str. EC4115 N-acetylneuraminic acid mutarotase YP_002273833.1 5466215 R 444450 CDS YP_002273834.1 209398737 6968997 complement(5467341..5467889) 1 NC_011353.1 identified by match to protein family HMM PF06178; oligogalacturonate-specific porin protein 5467889 6968997 ECH74115_5815 Escherichia coli O157:H7 str. EC4115 oligogalacturonate-specific porin protein YP_002273834.1 5467341 R 444450 CDS YP_002273835.1 209399448 6969813 5468295..5468423 1 NC_011353.1 identified by glimmer; hypothetical protein 5468423 6969813 ECH74115_5816 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273835.1 5468295 D 444450 CDS YP_002273836.1 209400769 6970576 complement(5468722..5468859) 1 NC_011353.1 identified by glimmer; hypothetical protein 5468859 6970576 ECH74115_5817 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273836.1 5468722 R 444450 CDS YP_002273837.1 209400483 6971994 5469513..5470115 1 NC_011353.1 inversion of on/off regulator of fimA; tyrosine recombinase 5470115 fimB 6971994 fimB Escherichia coli O157:H7 str. EC4115 tyrosine recombinase YP_002273837.1 5469513 D 444450 CDS YP_002273838.1 209398596 6971688 5470593..5471189 1 NC_011353.1 inversion of on/off regulator of fimA; tyrosine recombinase 5471189 fimE 6971688 fimE Escherichia coli O157:H7 str. EC4115 tyrosine recombinase YP_002273838.1 5470593 D 444450 CDS YP_002273839.1 209396019 6969658 5471654..5472202 1 NC_011353.1 identified by match to protein family HMM PF00419; type-1 fimbrial protein-like protein 5472202 6969658 ECH74115_5820 Escherichia coli O157:H7 str. EC4115 type-1 fimbrial protein-like protein YP_002273839.1 5471654 D 444450 CDS YP_002273840.1 209396777 6966892 5472309..5472806 1 NC_011353.1 identified by match to protein family HMM PF00419; type-1 fimbrial protein-like protein 5472806 6966892 ECH74115_5821 Escherichia coli O157:H7 str. EC4115 type-1 fimbrial protein-like protein YP_002273840.1 5472309 D 444450 CDS YP_002273841.1 209399598 6967707 5472843..5473568 1 NC_011353.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC 5473568 fimC 6967707 fimC Escherichia coli O157:H7 str. EC4115 chaperone protein FimC YP_002273841.1 5472843 D 444450 CDS YP_002273842.1 209397655 6970739 5473635..5476271 1 NC_011353.1 identified by match to protein family HMM PF00577; outer membrane usher protein fimD 5476271 fimD1 6970739 fimD1 Escherichia coli O157:H7 str. EC4115 outer membrane usher protein fimD YP_002273842.1 5473635 D 444450 CDS YP_002273843.1 209400351 6968638 5476281..5476811 1 NC_011353.1 identified by match to protein family HMM PF00419; fimbrial protein FimF 5476811 fimF 6968638 fimF Escherichia coli O157:H7 str. EC4115 fimbrial protein FimF YP_002273843.1 5476281 D 444450 CDS YP_002273844.1 209398557 6971549 5476824..5477327 1 NC_011353.1 identified by match to protein family HMM PF00419; protein fimG 5477327 fimG 6971549 fimG Escherichia coli O157:H7 str. EC4115 protein fimG YP_002273844.1 5476824 D 444450 CDS YP_002273845.1 209399868 6969617 5477347..5478249 1 NC_011353.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160; protein FimH 5478249 fimH 6969617 fimH Escherichia coli O157:H7 str. EC4115 protein FimH YP_002273845.1 5477347 D 444450 CDS YP_002273846.1 209400656 6971027 complement(5478423..5479766) 1 NC_011353.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; fructuronate transporter 5479766 gntP 6971027 gntP Escherichia coli O157:H7 str. EC4115 fructuronate transporter YP_002273846.1 5478423 R 444450 CDS YP_002273847.1 209398734 6971872 5480106..5481290 1 NC_011353.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5481290 uxuA 6971872 uxuA Escherichia coli O157:H7 str. EC4115 mannonate dehydratase YP_002273847.1 5480106 D 444450 CDS YP_002273848.1 209399476 6969809 5481371..5482831 1 NC_011353.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; fructuronate reductase 5482831 uxuB 6969809 uxuB Escherichia coli O157:H7 str. EC4115 fructuronate reductase YP_002273848.1 5481371 D 444450 CDS YP_002273849.1 209400181 6970609 5483046..5483819 1 NC_011353.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5483819 6970609 ECH74115_5830 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional repressor UxuR YP_002273849.1 5483046 D 444450 CDS YP_002273850.1 209400960 6971368 complement(5483960..5484790) 1 NC_011353.1 hypothetical protein 5484790 6971368 ECH74115_5831 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273850.1 5483960 R 444450 CDS YP_002273851.1 209397652 6972198 5485124..5485267 1 NC_011353.1 identified by glimmer; hypothetical protein 5485267 6972198 ECH74115_5832 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273851.1 5485124 D 444450 CDS YP_002273852.1 209398073 6968635 5485363..5485497 1 NC_011353.1 identified by glimmer; hypothetical protein 5485497 6968635 ECH74115_5833 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273852.1 5485363 D 444450 CDS YP_002273853.1 209396977 6969090 5485463..5485855 1 NC_011353.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5485855 iraD 6969090 iraD Escherichia coli O157:H7 str. EC4115 DNA replication/recombination/repair protein YP_002273853.1 5485463 D 444450 CDS YP_002273854.1 209400383 6967133 complement(5486824..5487996) 1 NC_011353.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR01975; isoaspartyl dipeptidase 5487996 iadA 6967133 iadA Escherichia coli O157:H7 str. EC4115 isoaspartyl dipeptidase YP_002273854.1 5486824 R 444450 CDS YP_002273855.1 209398485 6971583 complement(5488009..5488470) 1 NC_011353.1 identified by match to protein family HMM PF07670; hypothetical protein 5488470 6971583 ECH74115_5837 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273855.1 5488009 R 444450 CDS YP_002273856.1 209400264 6969542 complement(5488467..5489150) 1 NC_011353.1 identified by match to protein family HMM PF07670; transporter 5489150 6969542 ECH74115_5838 Escherichia coli O157:H7 str. EC4115 transporter YP_002273856.1 5488467 R 444450 CDS YP_002273857.1 209396723 6971457 5489180..5489371 1 NC_011353.1 identified by glimmer; hypothetical protein 5489371 6971457 ECH74115_5839 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273857.1 5489180 D 444450 CDS YP_002273858.1 209396495 6968143 complement(5495559..5496737) 1 NC_011353.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690; major facilitator family transporter 5496737 6968143 ECH74115_5844 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002273858.1 5495559 R 444450 CDS YP_002273859.1 209395762 6967407 complement(5496805..5497647) 1 NC_011353.1 identified by match to protein family HMM PF06977; SdiA-regulated protein 5497647 6967407 ECH74115_5845 Escherichia coli O157:H7 str. EC4115 SdiA-regulated protein YP_002273859.1 5496805 R 444450 CDS YP_002273860.1 209399931 6966617 complement(5497913..5500096) 1 NC_011353.1 identified by glimmer; hypothetical protein 5500096 6966617 ECH74115_5846 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273860.1 5497913 R 444450 CDS YP_002273861.1 209400337 6971096 complement(5500408..5500674) 1 NC_011353.1 hypothetical protein 5500674 6971096 ECH74115_5847 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273861.1 5500408 R 444450 CDS YP_002273862.1 209398356 6971534 complement(5500671..5501438) 1 NC_011353.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; (R)-2-hydroxyglutaryl-CoA dehydratase activator 5501438 hgdC 6971534 hgdC Escherichia coli O157:H7 str. EC4115 (R)-2-hydroxyglutaryl-CoA dehydratase activator YP_002273862.1 5500671 R 444450 CDS YP_002273863.1 209398248 6969397 complement(5501448..5502599) 1 NC_011353.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 5502599 6969397 ECH74115_5849 Escherichia coli O157:H7 str. EC4115 2-hydroxyglutaryl-CoA dehydratase subunit D YP_002273863.1 5501448 R 444450 CDS YP_002273864.1 209400166 6969280 complement(5502715..5503986) 1 NC_011353.1 identified by match to protein family HMM PF04286; hypothetical protein 5503986 6969280 ECH74115_5850 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273864.1 5502715 R 444450 CDS YP_002273865.1 209399400 6971352 complement(5504027..5505259) 1 NC_011353.1 identified by match to protein family HMM PF07690; multidrug resistance protein MdtM 5505259 mdtM 6971352 mdtM Escherichia coli O157:H7 str. EC4115 multidrug resistance protein MdtM YP_002273865.1 5504027 R 444450 CDS YP_002273866.1 209396633 6970526 5505517..5505690 1 NC_011353.1 identified by glimmer; hypothetical protein 5505690 6970526 ECH74115_5852 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273866.1 5505517 D 444450 CDS YP_002273867.1 209397786 6971890 complement(5506926..5508338) 1 NC_011353.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; transcriptional regulator, GntR family/aminotransferase, classes I and II 5508338 6971890 ECH74115_5854 Escherichia coli O157:H7 str. EC4115 transcriptional regulator, GntR family/aminotransferase, classes I and II YP_002273867.1 5506926 R 444450 CDS YP_002273868.1 209397187 6968774 5508515..5508679 1 NC_011353.1 identified by match to protein family HMM PF06568; hypothetical protein 5508679 6968774 ECH74115_5855 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273868.1 5508515 D 444450 CDS YP_002273869.1 209396668 6968527 complement(5510915..5511256) 1 NC_011353.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 5511256 6968527 ECH74115_5858 Escherichia coli O157:H7 str. EC4115 endoribonuclease SymE YP_002273869.1 5510915 R 444450 CDS YP_002273870.1 209396465 6967589 complement(5511477..5513231) 1 NC_011353.1 identified by match to protein family HMM PF01420; type I restriction-modification system subunit S 5513231 6967589 ECH74115_5859 Escherichia coli O157:H7 str. EC4115 type I restriction-modification system subunit S YP_002273870.1 5511477 R 444450 CDS YP_002273871.1 209398363 6967376 complement(5513231..5514712) 1 NC_011353.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02384; type I restriction-modification system, M subunit 5514712 6967376 ECH74115_5860 Escherichia coli O157:H7 str. EC4115 type I restriction-modification system, M subunit YP_002273871.1 5513231 R 444450 CDS YP_002273872.1 209398938 6969406 complement(5514767..5517199) 1 NC_011353.1 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463; type III restriction enzyme domain-containing protein 5517199 6969406 ECH74115_5861 Escherichia coli O157:H7 str. EC4115 type III restriction enzyme domain-containing protein YP_002273872.1 5514767 R 444450 CDS YP_002273873.1 209399880 6970238 complement(5519197..5520153) 1 NC_011353.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683; GTP-binding protein YjiA 5520153 6970238 ECH74115_5864 Escherichia coli O157:H7 str. EC4115 GTP-binding protein YjiA YP_002273873.1 5519197 R 444450 CDS YP_002273874.1 209400629 6971041 complement(5520164..5520367) 1 NC_011353.1 identified by match to protein family HMM PF04328; hypothetical protein 5520367 6971041 ECH74115_5865 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273874.1 5520164 R 444450 CDS YP_002273875.1 209396090 6971842 complement(5520417..5522582) 1 NC_011353.1 identified by match to protein family HMM PF02554; carbon starvation family protein 5522582 6971842 ECH74115_5866 Escherichia coli O157:H7 str. EC4115 carbon starvation family protein YP_002273875.1 5520417 R 444450 CDS YP_002273876.1 209395831 6966969 complement(5522860..5523402) 1 NC_011353.1 hypothetical protein 5523402 6966969 ECH74115_5867 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273876.1 5522860 R 444450 CDS YP_002273877.1 209396680 6966688 5523631..5525295 1 NC_011353.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein I 5525295 tsr 6966688 tsr Escherichia coli O157:H7 str. EC4115 methyl-accepting chemotaxis protein I YP_002273877.1 5523631 D 444450 CDS YP_002273878.1 209396159 6967601 complement(5525344..5526705) 1 NC_011353.1 identified by match to protein family HMM PF07690; major facilitator family transporter 5526705 6967601 ECH74115_5869 Escherichia coli O157:H7 str. EC4115 major facilitator family transporter YP_002273878.1 5525344 R 444450 CDS YP_002273879.1 209398199 6967042 complement(5526920..5527834) 1 NC_011353.1 identified by match to protein family HMM PF07729; GntR family transcriptional regulator 5527834 6967042 ECH74115_5870 Escherichia coli O157:H7 str. EC4115 GntR family transcriptional regulator YP_002273879.1 5526920 R 444450 CDS YP_002273880.1 209397114 6969227 5527973..5528995 1 NC_011353.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; oxidoreductase, zinc-binding dehydrogenase family 5528995 6969227 ECH74115_5871 Escherichia coli O157:H7 str. EC4115 oxidoreductase, zinc-binding dehydrogenase family YP_002273880.1 5527973 D 444450 CDS YP_002273881.1 209398633 6968063 complement(5529132..5531423) 1 NC_011353.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 5531423 mdoB 6968063 mdoB Escherichia coli O157:H7 str. EC4115 phosphoglycerol transferase I YP_002273881.1 5529132 R 444450 CDS YP_002273882.1 209397906 6969698 complement(5531677..5532174) 1 NC_011353.1 hypothetical protein 5532174 6969698 ECH74115_5873 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273882.1 5531677 R 444450 CDS YP_002273883.1 209399469 6968904 complement(5532220..5532957) 1 NC_011353.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 5532957 dnaC 6968904 dnaC Escherichia coli O157:H7 str. EC4115 DNA replication protein DnaC YP_002273883.1 5532220 R 444450 CDS YP_002273884.1 209398718 6970601 complement(5532960..5533499) 1 NC_011353.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 5533499 dnaT 6970601 dnaT Escherichia coli O157:H7 str. EC4115 primosomal protein DnaI YP_002273884.1 5532960 R 444450 CDS YP_002273885.1 209396091 6969790 complement(5533606..5534079) 1 NC_011353.1 overlaps another CDS with the same product name; hypothetical protein 5534079 6969790 ECH74115_5876 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273885.1 5533606 R 444450 CDS YP_002273886.1 209400987 6966970 complement(5534070..5534894) 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF06738; hypothetical protein 5534894 6966970 ECH74115_5877 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273886.1 5534070 R 444450 CDS YP_002273887.1 209399682 6972229 5535461..5536186 1 NC_011353.1 overlaps another CDS with the same product name; identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 5536186 6972229 ECH74115_5878 Escherichia coli O157:H7 str. EC4115 LuxR family transcriptional regulator YP_002273887.1 5535461 D 444450 CDS YP_002273888.1 209399260 6970831 5536144..5536821 1 NC_011353.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5536821 6970831 ECH74115_5879 Escherichia coli O157:H7 str. EC4115 DNA-binding transcriptional activator BglJ YP_002273888.1 5536144 D 444450 CDS YP_002273889.1 209396973 6970376 complement(5536859..5537647) 1 NC_011353.1 identified by match to protein family HMM PF06276; ferric hydroximate transport ferric iron reductase 5537647 fhuF 6970376 fhuF Escherichia coli O157:H7 str. EC4115 ferric hydroximate transport ferric iron reductase YP_002273889.1 5536859 R 444450 CDS YP_002273890.1 209396220 6967913 5537749..5538024 1 NC_011353.1 identified by match to protein family HMM PF07256; hypothetical protein 5538024 6967913 ECH74115_5881 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273890.1 5537749 D 444450 CDS YP_002273891.1 209398157 6972339 complement(5538339..5539370) 1 NC_011353.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 5539370 rsmC 6972339 rsmC Escherichia coli O157:H7 str. EC4115 16S ribosomal RNA m2G1207 methyltransferase YP_002273891.1 5538339 R 444450 CDS YP_002273892.1 209397348 6969181 5539473..5539886 1 NC_011353.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5539886 holD 6969181 holD Escherichia coli O157:H7 str. EC4115 DNA polymerase III subunit psi YP_002273892.1 5539473 D 444450 CDS YP_002273893.1 209399282 6968315 5539855..5540301 1 NC_011353.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5540301 rimI 6968315 rimI Escherichia coli O157:H7 str. EC4115 ribosomal-protein-alanine N-acetyltransferase YP_002273893.1 5539855 D 444450 CDS YP_002273894.1 209398693 6970398 5540316..5540993 1 NC_011353.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5540993 yjjG 6970398 yjjG Escherichia coli O157:H7 str. EC4115 nucleotidase YP_002273894.1 5540316 D 444450 CDS YP_002273895.1 209399061 6969765 5541084..5542673 1 NC_011353.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5542673 prfC 6969765 prfC Escherichia coli O157:H7 str. EC4115 peptide chain release factor 3 YP_002273895.1 5541084 D 444450 CDS YP_002273896.1 209398467 6970163 5543066..5543671 1 NC_011353.1 identified by match to protein family HMM PF04972; hypothetical protein 5543671 osmY 6970163 osmY Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273896.1 5543066 D 444450 CDS YP_002273897.1 209400823 6969521 5543798..5543959 1 NC_011353.1 identified by glimmer; hypothetical protein 5543959 6969521 ECH74115_5889 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273897.1 5543798 D 444450 CDS YP_002273898.1 209398730 6972051 5544081..5545154 1 NC_011353.1 identified by match to protein family HMM PF01734; phospholipase, patatin family 5545154 6972051 ECH74115_5890 Escherichia coli O157:H7 str. EC4115 phospholipase, patatin family YP_002273898.1 5544081 D 444450 CDS YP_002273899.1 209397271 6969804 5545151..5545933 1 NC_011353.1 identified by match to protein family HMM PF01026; deoxyribonuclease YjjV 5545933 6969804 ECH74115_5891 Escherichia coli O157:H7 str. EC4115 deoxyribonuclease YjjV YP_002273899.1 5545151 D 444450 CDS YP_002273900.1 209397872 6968231 complement(5546147..5547010) 1 NC_011353.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 5547010 6968231 ECH74115_5892 Escherichia coli O157:H7 str. EC4115 radical SAM domain-containing protein YP_002273900.1 5546147 R 444450 CDS YP_002273901.1 209396928 6966671 5548507..5548632 1 NC_011353.1 hypothetical protein 5548632 6966671 ECH74115_5895 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273901.1 5548507 D 444450 CDS YP_002273902.1 209400237 6967866 5548789..5549568 1 NC_011353.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5549568 deoC 6967866 deoC Escherichia coli O157:H7 str. EC4115 deoxyribose-phosphate aldolase YP_002273902.1 5548789 D 444450 CDS YP_002273903.1 209398702 6971427 5549695..5551017 1 NC_011353.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5551017 deoA 6971427 deoA Escherichia coli O157:H7 str. EC4115 thymidine phosphorylase YP_002273903.1 5549695 D 444450 CDS YP_002273904.1 209399462 6969774 5551069..5552292 1 NC_011353.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5552292 deoB 6969774 deoB Escherichia coli O157:H7 str. EC4115 phosphopentomutase YP_002273904.1 5551069 D 444450 CDS YP_002273905.1 209400497 6970592 5552349..5553068 1 NC_011353.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5553068 deoD 6970592 deoD Escherichia coli O157:H7 str. EC4115 purine nucleoside phosphorylase YP_002273905.1 5552349 D 444450 CDS YP_002273906.1 209399734 6971702 complement(5553229..5553492) 1 NC_011353.1 identified by match to protein family HMM PF01381; hypothetical protein 5553492 6971702 ECH74115_5900 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273906.1 5553229 R 444450 CDS YP_002273907.1 209399317 6970887 complement(5553524..5555212) 1 NC_011353.1 in E. coli the lipoate ligase A catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes; creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; hypothetical protein/lipoate-protein ligase A fusion protein 5555212 6970887 ECH74115_5901 Escherichia coli O157:H7 str. EC4115 hypothetical protein/lipoate-protein ligase A fusion protein YP_002273907.1 5553524 R 444450 CDS YP_002273908.1 209398522 6970436 5555318..5556286 1 NC_011353.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5556286 serB 6970436 serB Escherichia coli O157:H7 str. EC4115 phosphoserine phosphatase YP_002273908.1 5555318 D 444450 CDS YP_002273909.1 209397317 6969581 5556335..5557717 1 NC_011353.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5557717 radA 6969581 radA Escherichia coli O157:H7 str. EC4115 DNA repair protein RadA YP_002273909.1 5556335 D 444450 CDS YP_002273910.1 209397888 6968279 5557738..5558970 1 NC_011353.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5558970 nadR 6968279 nadR Escherichia coli O157:H7 str. EC4115 nicotinamide-nucleotide adenylyltransferase YP_002273910.1 5557738 D 444450 CDS YP_002273911.1 209395789 6968885 5559004..5559171 1 NC_011353.1 hypothetical protein 5559171 6968885 ECH74115_5905 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273911.1 5559004 D 444450 CDS YP_002273912.1 209400314 6966645 complement(5559278..5560945) 1 NC_011353.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 5560945 6966645 ECH74115_5906 Escherichia coli O157:H7 str. EC4115 ABC transporter ATP-binding protein YP_002273912.1 5559278 R 444450 CDS YP_002273913.1 209400298 6971510 5561156..5563093 1 NC_011353.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5563093 slt 6971510 slt Escherichia coli O157:H7 str. EC4115 lytic murein transglycosylase YP_002273913.1 5561156 D 444450 CDS YP_002273914.1 209400910 6971492 5563183..5563509 1 NC_011353.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5563509 trpR 6971492 trpR Escherichia coli O157:H7 str. EC4115 Trp operon repressor YP_002273914.1 5563183 D 444450 CDS YP_002273915.1 209398147 6972146 complement(5563656..5564177) 1 NC_011353.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 5564177 6972146 ECH74115_5909 Escherichia coli O157:H7 str. EC4115 NTPase YP_002273915.1 5563656 R 444450 CDS YP_002273916.1 209397025 6969170 5564220..5564867 1 NC_011353.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5564867 6969170 ECH74115_5911 Escherichia coli O157:H7 str. EC4115 phosphoglycerate mutase YP_002273916.1 5564220 D 444450 CDS YP_002273917.1 209397394 6967969 complement(5564864..5565733) 1 NC_011353.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; right origin-binding protein 5565733 rob 6967969 rob Escherichia coli O157:H7 str. EC4115 right origin-binding protein YP_002273917.1 5564864 R 444450 CDS YP_002273918.1 209399268 6968360 5565944..5566417 1 NC_011353.1 identified by match to protein family HMM PF05981; hypothetical protein 5566417 6968360 ECH74115_5912 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273918.1 5565944 D 444450 CDS YP_002273919.1 209399995 6970384 5566430..5567119 1 NC_011353.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5567119 creB 6970384 creB Escherichia coli O157:H7 str. EC4115 DNA-binding response regulator CreB YP_002273919.1 5566430 D 444450 CDS YP_002273920.1 209396415 6971167 5567119..5568543 1 NC_011353.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5568543 creC 6971167 creC Escherichia coli O157:H7 str. EC4115 sensory histidine kinase CreC YP_002273920.1 5567119 D 444450 CDS YP_002273921.1 209396151 6967322 5568601..5569953 1 NC_011353.1 identified by match to protein family HMM PF06123; hypothetical protein 5569953 6967322 ECH74115_5915 Escherichia coli O157:H7 str. EC4115 hypothetical protein YP_002273921.1 5568601 D 444450 CDS YP_002273922.1 209398070 6967034 complement(5570013..5570729) 1 NC_011353.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two-component response regulator 5570729 arcA 6967034 arcA Escherichia coli O157:H7 str. EC4115 two-component response regulator YP_002273922.1 5570013 R 444450 CDS YP_002273923.1 209397370 6969087 5571365..5572051 1 NC_011353.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5572051 6969087 ECH74115_5917 Escherichia coli O157:H7 str. EC4115 RNA methyltransferase YP_002273923.1 5571365 D 444450 CDS